http://identifiers.org/biomodels.db/MODEL1109130000#_394875f2_e9e8_4531_bdc7_43323e6cbc91
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a325fa0a_25ae_4462_8113_22106d799ff7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_331fc42e_c3bb_4a96_ad16_15274c00a6d8
value: -1000.0
type: LocalParameter

metaM dcyt e
is: SBO:0000247
is: CHEBI:15698
is: C00881
has only substance units: false
boundary condition: false
initial amount: NaN
initial concentration: 1.0
is: HMDB00014
name: Deoxycytidine
notes: FORMULA: C9H13N3O4 CHARGE: 0 HEPATONET_1.0_ABBREVIATION: HC00574 EHMN_ABBREVIATION: C00881 INCHI: InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
type: Species
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_72ff1989_ed58_4a75_849c_1e959e04975d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2a31b80e_a2a9_4c04_82ff_f579370641ff
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_481bcad6_1834_4f8a_ab9f_d5a41e070342
units: dimensionless
value: 0.0
type: LocalParameter

metaR SELADT
fast: false
is version of: ECO:0000212
is: SBO:0000176
is described by: http://identifiers.org/pubmed/10679223
reversible: false
type: Reaction
notes: GENE_ASSOCIATION: (9061.1) or (9060.1) SUBSYSTEM: Selenoamino acid metabolism EC Number: 2.7.7.4 Confidence Level: 1 AUTHORS: PMID:10679223 NOTES: SAB
is version of: http://identifiers.org/ec-code/2.7.7.4
product: MODEL1109130000#
name: selenate adenylyltransferase
reactant: MODEL1109130000#
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#d7a9590d_aeaa_4cc4_9721_39b3bfb3afba
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_41ccec6a_d572_4da4_84d1_9577c4a003d5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2d2e59c0_8b32_4cf7_a5bc_961d9acae29d
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2251bc5f_a50f_4e23_a53e_272bc745e509
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_458d886f_7fc6_4207_9d7d_d74775d3f7a5
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_10f6a477_7e75_4470_bde0_041833017991
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f66cb593_b25a_469e_a0b4_89ac7dbe1792
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4e16397a_50c7_428c_ab6a_7fb7427890a1
boundary condition: true
initial amount: NaN
type: Species
constant: false
is encoded by: hsa:28231
initial concentration: NaN
name: SLCO4A1
is: Q96BD0
has only substance units: false
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_076fda77_b957_4762_a06a_3c09f7411c89
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d54e09fc_fdf2_44c6_8098_41f72f8a6357
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_93144aed_38a2_4c57_983a_f09ca99c3b62
value: 0.0
type: LocalParameter

metaM CE2953 c
initial concentration: 1.0
notes: FORMULA: C20H27O3 CHARGE: -1 INCHI: InChI=1/C20H28O3/c1-15(8-6-9-16(2)14-17(21)22)10-13-20-18(3,4)11-7-12-19(20,5)23-20/h6,8-10,13-14H,7,11-12H2,1-5H3,(H,21,22)/p-1/b9-6+,13-10+,15-8+,16-14+ EHMN_ABBREVIATION: CE2953
boundary condition: false
type: Species
constant: false
is: SBO:0000247
has only substance units: false
name: rac-5,6-epoxy-retinoate
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_72d52163_ed32_484f_9732_cc08ed1f9735
value: -1000.0
type: LocalParameter

metaM core6 g
boundary condition: false
name: Core 6
constant: false
has only substance units: false
type: Species
is: SBO:0000247
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C16H27N2O10X CHARGE: 0 INCHI:

metaR RE2151R
is version of: http://identifiers.org/ec-code/2.4.1.17
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: false
name: RE2151
is described by: http://identifiers.org/pubmed/8295481
type: Reaction
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Vitamin A metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:8295481 NOTES:
is: SBO:0000176
modifier: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6639cabc_de8a_4e38_bea0_f0a30b253574
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3e727eae_cc03_4e44_83a4_9baed07e487d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_112b84b0_06f0_428b_b5fb_388f0329a504
value: -1000.0
type: LocalParameter

metaR EX dpcoa LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for dpcoa
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_9b64393c_ffd5_45e2_979b_b621be0df8ec
value: 1000.0
type: LocalParameter

metaM htaxol e
boundary condition: false
constant: false
type: Species
is: SBO:0000247
name: 6 alpha hydroxy taxol/ 6 alpha hydroxy paclitaxel
initial amount: NaN
initial concentration: 1.0
has only substance units: false
notes: FORMULA: C47H31NO15 CHARGE: 0 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#e2af4b6f_a01e_481e_a8e2_091140b4e131
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7029be81_bd6e_43fd_a16d_69e2405d3c56
value: 1000.0
type: LocalParameter

metaR r0741
is described by: http://identifiers.org/pubmed/271969
product: MODEL1109130000#
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Bile acid synthesis EC Number: 1.14.13.15 Confidence Level: 0 AUTHORS: PMID:1591235,PMID:271969,PMID:4026854,PMID:7077149 NOTES: IT - HepatoNet mapping of HC01455 to dhochoylcoa was wrong, xoltetrol is correct mapping. Therefore, r0742 is identical to P45027A11m and r0741 is cytosol version of P45027A11m
is described by: http://identifiers.org/pubmed/4026854
is described by: http://identifiers.org/pubmed/1591235
is described by: http://identifiers.org/pubmed/7077149
type: Reaction
reactant: MODEL1109130000#
name: 5beta-Cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating) Bile acid biosynthesis EC:1.14.13.15
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.14.13.15
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#f0c3c3d2_a640_475d_b38c_3b0ca1a863c4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d68b6cf9_3091_4381_8343_1e1a7db02abc
name: NOS3
is encoded by: hsa:4846
constant: false
initial concentration: NaN
is: SBO:0000252
has only substance units: false
boundary condition: true
is: A0S0A7
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_6de08014_859d_4416_8c5f_2d7b69b3bd8b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74cf16c2_098b_48a1_a601_df577231689e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7db171cd_ac58_417e_9b3c_72c832d1be22
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC00229 e
type: Species
is: CHEBI:28189
notes: FORMULA: C12H22O11 CHARGE: 0 INCHI: InChI=1S/C12H22O11/c13-1-4(15)7(17)8(18)5(16)3-22-12-11(21)10(20)9(19)6(2-14)23-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9+,10-,11+,12-/m0/s1 EHMN_ABBREVIATION: C00252
is: SBO:0000247
constant: false
name: Isomaltose
has only substance units: false
initial concentration: 1.0
initial amount: NaN
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#b3e449f0_20d1_460f_9165_c0cf4ea09c34
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b61cc59d_1635_430d_a5e5_c5a49de0bc92
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9d51d438_2e4e_4095_ad67_66b4044fbbe1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ce288332_1c5c_423f_bae3_0e2414da02af
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed9a0761_314f_4f23_8358_76aff4a32cfa
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE2632C
notes: GENE_ASSOCIATION: SUBSYSTEM: Bile acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:9660774 NOTES:
fast: false
is: SBO:0000176
reversible: false
reactant: MODEL1109130000#
product: MODEL1109130000#
type: Reaction
name: RE2632
is described by: http://identifiers.org/pubmed/9660774

metaM tdchola x
notes: FORMULA: C26H45NO6S CHARGE: 0 INCHI: InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22-,24+,25+,26-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC01471 EHMN_ABBREVIATION: C05465
constant: false
is: HMDB00951
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247
is: CHEBI:9407
name: taurochenodeoxycholate
boundary condition: false
has only substance units: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_59427aa2_14c1_4edb_b1a5_167dc52ee79c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d513eb68_ad8f_40b6_b392_90b6e458f4df
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d42a33a0_ae60_4b33_9275_61bbb38a153b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0d8b85ec_adaa_4160_972c_8cb888c74e74
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_966055d1_d55a_493f_803f_b721c7f7e7c6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fc3c7520_6689_47bb_ac7e_ebc944bf2867
value: 0.0
type: LocalParameter

metaR r0743
name: hydroxysteroid (17-beta) dehydrogenase 4 Bile acid biosynthesis EC:1.1.1.35
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/11330072
reversible: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Bile acid synthesis EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:11330072 NOTES:
is version of: http://identifiers.org/ec-code/1.1.1.35
type: Reaction
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_0754bd93_af74_4da9_8b33_291db04765eb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b042141_ed68_4f14_a357_709234aada97
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0155dcff_6aa3_48d6_b39b_d3285e2264e3
value: 0.0
type: LocalParameter

metaM pyr m
notes: FORMULA: C3H3O3 CHARGE: -1 HEPATONET_1.0_ABBREVIATION: HC00032 EHMN_ABBREVIATION: C00022 INCHI: InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/p-1
constant: false
is: HMDB00243
has only substance units: false
name: pyruvate
type: Species
initial amount: NaN
is: http://identifiers.org/pubchem.substance/3324
boundary condition: false
is: C00022
initial concentration: 1.0
is: SBO:0000247
is: CHEBI:15361

http://identifiers.org/biomodels.db/MODEL1109130000#_7b740358_f942_4178_9cba_e1764693d8c8
value: 1000.0
type: LocalParameter

metaM ipdp r
notes: FORMULA: C5H9O7P2 CHARGE: -3 INCHI: InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8)/p-3 HEPATONET_1.0_ABBREVIATION: HC00127 EHMN_ABBREVIATION: C00129
constant: false
name: isopentenyl diphosphate(3-)
initial amount: NaN
is: HMDB01347
has only substance units: false
is: SBO:0000247
initial concentration: 1.0
is: CHEBI:128769
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_0f4b30af_935f_46de_a6d8_285b737de63a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d8fc44e8_040f_493f_bc19_3b5b60a653bb
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5121 x
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247
constant: false
name: trans-3-decenoyl-CoA
boundary condition: false
type: Species
notes: FORMULA: C31H48N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5121
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_28f00c90_068a_4e19_979b_915135a0bef2
value: 0.0
type: LocalParameter

metaR r0744
is version of: http://identifiers.org/ec-code/4.2.1.107
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Bile acid synthesis EC Number: 4.2.1.107 Confidence Level: 0 AUTHORS: PMID:11330072 NOTES:
fast: false
reactant: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/11330072
name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl- CoA hydro-lyase Bile acid biosynthesis EC:4.2.1.107
product: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_5e612000_deb8_4bb9_af78_c5697fb2909f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3be9e8b5_f133_44a9_b54c_4a6a47f8ffb4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e6c1cc5c_cf1f_4265_a200_9fe53e3ea3a0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bec2cacc_0529_452c_825c_61020388ab78
value: 1000.0
type: LocalParameter

metaM dcyt c
is: SBO:0000247
constant: false
boundary condition: false
type: Species
initial concentration: 1.0
has only substance units: false
is: CHEBI:15698
is: C00881
name: Deoxycytidine
initial amount: NaN
is: HMDB00014
notes: FORMULA: C9H13N3O4 CHARGE: 0 HEPATONET_1.0_ABBREVIATION: HC00574 EHMN_ABBREVIATION: C00881 INCHI: InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1

http://identifiers.org/biomodels.db/MODEL1109130000#_312716ab_c373_4da6_80fe_55c066341fb8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7d1a8045_a516_4aa3_b219_de1753d17b7d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4be47b32_35f3_4d9c_9211_dc3d9608e555
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_49ef6440_58e2_4b7d_aa89_4ec19907c9f7
units: dimensionless
value: 0.0
type: LocalParameter

metaM nmn c
is: C00455
name: NMN
is: CHEBI:14649
initial amount: NaN
constant: false
type: Species
boundary condition: false
is: SBO:0000247
notes: FORMULA: C11H14N2O8P CHARGE: -1 HEPATONET_1.0_ABBREVIATION: HC00366 EHMN_ABBREVIATION: C00455 INCHI: InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/p-1/t7-,8-,9-,11-/m1/s1
is: HMDB00229
initial concentration: 1.0
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_69b25fc2_7222_4bf5_a607_8bc69b4f2bd6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1848c468_51ea_43a5_8c77_67e156b17b64
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eb68dfa8_501e_4e16_a77a_98bd3c7fb44e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a39f3828_91a4_4996_a074_750aec921321
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ac85e23c_9f7a_4afb_a21d_1dc65ca6176c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b16ce725_0648_4ea8_8be9_5c4ce8c83805
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7e6a4dc8_796a_438a_bffb_76025446ae13
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b9a11723_0531_422d_adda_50e27c110ef2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_966b3bbf_b8cf_4278_88cb_db245964c773
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0385041b_6106_4a82_9fec_3c960a07b504
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a0f482d_e529_4e31_9bc4_909d003a57a4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b188e659_505e_464c_b3f8_4ed5bf915190
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3bf29c6a_6dbc_47aa_a415_af2581f0ed04
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17c26d05_527a_4258_a089_ba739bc889cd
value: 0.0
type: LocalParameter

metaR EX gam LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for D-Glucosamine
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_10bd16db_a9c6_418e_841d_d6eab730b745
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b2955de_55ed_4d87_a533_73f17a778f5c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bc2124b2_6c30_4b12_a92c_64ec1259f77f
value: 0.0
type: LocalParameter

metaR r0747
is described by: http://identifiers.org/pubmed/1554355
is described by: http://identifiers.org/pubmed/1591235
is version of: http://identifiers.org/ec-code/1.1.1.50
reversible: true
product: MODEL1109130000#
type: Reaction
name: 3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50
reactant: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Bile acid synthesis EC Number: 1.1.1.50 Confidence Level: 0 AUTHORS: PMID:1554355,PMID:1591235,PMID:3459552 NOTES:
is described by: http://identifiers.org/pubmed/3459552
is: SBO:0000176
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#e381fd9b_929a_4adf_8574_e73c70597bf5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8952c335_0856_45e9_b680_bbec2160e2e9
units: dimensionless
value: 0.0
type: LocalParameter

metaR MACOXO
reversible: false
is version of: ECO:0000269
product: MODEL1109130000#
fast: false
is: SBO:0000176
notes: GENE_ASSOCIATION: (218.1) or (221.1) or (4129.1) or (222.1) or (220.1) SUBSYSTEM: Histidine metabolism EC Number: 1.2.1.5 Confidence Level: 4 AUTHORS: PMID:10344773 NOTES: SAB added 2 h to balance--not certain
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10344773
name: 3-Methylimidazole acetaldehyde:NAD+ oxidoreductase
type: Reaction
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.2.1.5

http://identifiers.org/biomodels.db/MODEL1109130000#_8c43686c_131c_44c5_82e7_6123fdd67327
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5d671b5b_95ed_418c_aa6e_357f47c066b2
is: P36537
name: UGT2B10
type: Species
initial concentration: NaN
initial amount: NaN
is: SBO:0000252
constant: true
has only substance units: false
is encoded by: hsa:7365
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_32c0c63a_df11_4793_a7ee_870c97e89c0e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e5cdd634_f529_483e_8edc_a09f0aa997b8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_129568ac_6947_46ed_b3f3_9bc9799839ba
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_42be9dd2_88fa_4fe1_832b_429a57792ecb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2707733b_1935_454e_8104_6ff099860402
name: MSMO1
type: Species
has only substance units: false
initial concentration: NaN
is encoded by: hsa:6307
is: A8MYF6
is: SBO:0000252
constant: false
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_7618fd60_1819_4725_82c2_2c38a6eba982
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d49cfbc5_1022_4d4f_8a4c_19ad97ce46e5
has only substance units: false
is: SBO:0000252
initial concentration: NaN
is: Q9UL12
constant: true
boundary condition: true
type: Species
initial amount: NaN
is encoded by: hsa:1757
name: SARDH

metaM m5masnB2 g
type: Species
notes: FORMULA: C52H87N2O40X CHARGE: 0 INCHI:
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
has only substance units: false
constant: false
initial concentration: 1.0
is: SBO:0000247
initial amount: NaN
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#d36c06ff_da20_4a23_859a_252fb647d056
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7a3c985a_1ab9_473e_95ee_806a7c7c860d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_320bd097_40c2_4d08_8257_0d0b71705ee8
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6dbe8844_57ca_41db_b711_c75ba5f9b9e5
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4d7aaa89_80f3_4c75_a8f9_85d2d9cc3439
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_52194010_f6c2_407b_abec_84797b6cd083
value: 1000.0
type: LocalParameter

metaR EX perillyl LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Perillyl alcohol exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#c8ad00a0_463a_40eb_85e6_bbc87db66b6a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_682109cd_6db5_49e0_8bb7_7803cbd52f0c
value: 0.0
type: LocalParameter

metaR C3STDH1Pr
is described by: http://identifiers.org/pubmed/10710235
fast: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 50814.1 SUBSYSTEM: Cholesterol metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:10710235,PMID:14506130 NOTES: NCD ER version NJ
product: MODEL1109130000#
type: Reaction
is: SBO:0000176
name: C-3 sterol dehydrogenase (4-methylzymosterol)
reactant: MODEL1109130000#
is version of: ECO:0000134
reversible: false
is described by: http://identifiers.org/pubmed/14506130

http://identifiers.org/biomodels.db/MODEL1109130000#dc449736_19ff_4671_9ae0_3f04869fe1d8
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#efca4cd4_d13a_402b_818a_a5e5a0baff90
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4db76e3d_aa89_4465_a75e_a7a767e75185
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5c1621c2_a618_4f65_ab73_e30d1e57a8a9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2d5689ec_ba4f_475c_b754_ff8bbda1b932
value: -1000.0
type: LocalParameter

metaM ksii core4 pre8 g
notes: FORMULA: C83H134N7O61SX CHARGE: -2 INCHI:
is: SBO:0000247
has only substance units: false
name: keratan sulfate II biosynthesis, precursor 8
boundary condition: false
initial concentration: 1.0
type: Species
initial amount: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_512ddca1_789f_4184_8115_bb11d0ff7606
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_27c43761_8535_44c6_b5b5_61b35a19a3eb
initial amount: NaN
is: SBO:0000252
is: P00367
boundary condition: true
has only substance units: false
constant: true
name: GLUD1
initial concentration: NaN
is encoded by: hsa:2746
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_42e5b59d_d2b5_43fb_87b3_c8dc59cef1e8
value: 0.0
type: LocalParameter

metaM ipdp x
initial concentration: 1.0
is: HMDB01347
name: isopentenyl diphosphate(3-)
is: CHEBI:128769
boundary condition: false
is: SBO:0000247
initial amount: NaN
type: Species
constant: false
has only substance units: false
notes: FORMULA: C5H9O7P2 CHARGE: -3 INCHI: InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8)/p-3 HEPATONET_1.0_ABBREVIATION: HC00127 EHMN_ABBREVIATION: C00129

metaR sink dd2coa LPAREN c RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: DD2COASINK
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_21bcf4f7_e26f_4e6d_8286_0314896ad9ba
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_10e83074_3571_43d9_91cc_094c3a50d023
value: 1000.0
type: LocalParameter

metaR HDCACBP
product: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 3 AUTHORS: PMID: 20511713, PMID: 11859412, PMID: 16908521, PMID: 8001684 EC Number: NOTES: acyl coA binding protein is localized in cytosol, nucelus, golgi, E.R., mitochondrial inter memebrane space. In mitochondria its released when the integrity of the organelle is compromised. It has wide role in lipid metabolism, also acts as a coA transporter between different cellular compartments. can transport accumulated acyl coAs from cutosol into mitochondria for beta oxidation or into cytosol for either transport into other compartemnts or for elliciting signalling cascades. GENE_ASSOCIATION: 1622.1
type: Reaction
is described by: http://identifiers.org/pubmed/16908521
name: transport of (S)-3-Hydroxydecanoyl-CoA from mitochondria into the cytosol
fast: false
is described by: http://identifiers.org/pubmed/11859412
modifier: MODEL1109130000#
reactant: MODEL1109130000#
reversible: true
is: SBO:0000185
is described by: http://identifiers.org/pubmed/8001684
is described by: http://identifiers.org/pubmed/20511713

http://identifiers.org/biomodels.db/MODEL1109130000#_d88a5fec_db5c_44c0_9517_442057cd6fbd
is encoded by: hsa:219
is: SBO:0000252
boundary condition: true
is: P30837
initial amount: NaN
type: Species
constant: false
name: ALDH1B1
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_44e661f5_b641_4180_9473_ab920d3f53b3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_39179a45_9c4d_4794_94cb_b9020f3204ab
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_284dcf48_8503_4641_b1d3_633ea6438b87
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8a4530fa_9c1d_4048_811e_64d8cb80b883
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c8424655_a44b_4e02_b02a_5f16fe917c64
value: 1000.0
type: LocalParameter

metaR SPMS
is described by: http://identifiers.org/pubmed/2069720
notes: GENE_ASSOCIATION: 6723.1 SUBSYSTEM: Urea cycle EC Number: 2.5.1.16 Confidence Level: 4 AUTHORS: PMID:2069720,PMID:8343131 NOTES:
reactant: MODEL1109130000#
is version of: ECO:0000269
type: Reaction
name: spermidine synthase
modifier: MODEL1109130000#
is: SBO:0000176
product: MODEL1109130000#
reversible: false
fast: false
is version of: http://identifiers.org/ec-code/2.5.1.16
is described by: http://identifiers.org/pubmed/8343131

http://identifiers.org/biomodels.db/MODEL1109130000#e2391208_630f_4368_a246_3eef34df685e
units: dimensionless
value: 0.0
type: LocalParameter

metaM pyr e
has only substance units: false
constant: false
type: Species
notes: FORMULA: C3H3O3 CHARGE: -1 INCHI: InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/p-1 HEPATONET_1.0_ABBREVIATION: HC00032 EHMN_ABBREVIATION: C00022
is: CHEBI:15361
initial concentration: 1.0
is: HMDB00243
boundary condition: false
initial amount: NaN
name: pyruvate
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_56fd2291_2931_4dca_8673_daa8ed164f61
initial amount: NaN
is: SBO:0000252
name: PLA2G6
has only substance units: false
boundary condition: true
constant: true
type: Species
initial concentration: NaN
is encoded by: hsa:8398
is: O60733

metaR OIVD1m
is version of: http://identifiers.org/ec-code/1.8.1.4
product: MODEL1109130000#
fast: false
reactant: MODEL1109130000#
is version of: ECO:0000269
is: SBO:0000176
notes: GENE_ASSOCIATION: (1629.1) and (594.1 and 593.1) and (1738.1) or (1629.1) and (1738.1) and (594.2 and 593.1) SUBSYSTEM: Valine, leucine, and isoleucine metabolism EC Number: 1.8.1.4 Confidence Level: 4 AUTHORS: PMID:1429740,PMID:2914958 NOTES:
is described by: http://identifiers.org/pubmed/1429740
type: Reaction
name: 2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial
reversible: false
is described by: http://identifiers.org/pubmed/2914958
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#f4735351_f4b9_4348_8e7d_e0ae95ee6f1d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8603f319_3efb_4c9b_af36_25c2657297de
initial amount: NaN
name: null
constant: true
is: SBO:0000252
initial concentration: NaN
boundary condition: true
type: Species
is encoded by: hsa:HG2846HT2983
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#bbd702ff_5dc7_466a_bf9f_2d440f638f6c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4c29ff3c_8d7b_407b_b5b9_af4fbc5b98e9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a446b6e_702d_4d56_9002_555fefa6f4e2
initial concentration: NaN
has only substance units: false
type: Species
initial amount: NaN
boundary condition: true
is: SBO:0000252
is: O95622
name: ADCY5
constant: false
is encoded by: hsa:111

http://identifiers.org/biomodels.db/MODEL1109130000#ec37850d_5100_4299_8b07_ddcac8de6a4d
units: dimensionless
value: 0.0
type: LocalParameter

metaM htaxol c
constant: false
name: 6 alpha hydroxy taxol/ 6 alpha hydroxy paclitaxel
has only substance units: false
is: SBO:0000247
initial concentration: 1.0
initial amount: NaN
boundary condition: false
type: Species
notes: FORMULA: C47H31NO15 CHARGE: 0 INCHI:

metaR DM n5m2masn g
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 0 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: false
name: DM n5m2masn(g)
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#c13addc8_fa2b_4843_a061_eab9764d93a4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_36b2e976_8205_4715_9556_2ed33a395f49
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ca90dbdc_3e45_4c93_8d0d_5f7398557390
is: SBO:0000252
is: O14684
boundary condition: true
initial concentration: NaN
initial amount: NaN
type: Species
has only substance units: false
is encoded by: hsa:9536
constant: true
name: PTGES

http://identifiers.org/biomodels.db/MODEL1109130000#_2f4ad090_a91b_4f20_ad06_f40558624d55
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b5cb6c65_cba5_4fbe_8d00_6da452819d1b
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: NDUFA11:NDUFS7:ND1:ND2:ND3:ND4:ND4L:ND5:ND6:NDUFA1:NDUFA2:NDUFA3:NDUFA4:NDUFA5:NDUFA6:NDUFA7:NDUFA8:NDUFA9:NDUFA10:NDUFAB1:NDUFB1:NDUFB2:NDUFB3:NDUFB4:NDUFB5:NDUFB6:NDUFB7:NDUFB8:NDUFB9:NDUFB10:NDUFC1:NDUFC2:NDUFS1:NDUFS2:NDUFS3:NDUFV1:NDUFS4:NDUFS5:NDUFS6:NDUFS8:NDUFV2:NDUFV3:NDUFA13:NDUFA12:TUSC3
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_28bd3b39_df07_4701_96db_aa0cfe46cc71
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17df2ab4_d665_4d9f_b12c_a395e2f6db14
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE3103R
notes: GENE_ASSOCIATION: 64834.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
fast: false
reactant: MODEL1109130000#
is: SBO:0000176
name: RE3103
product: MODEL1109130000#
type: Reaction
reversible: false
is described by: http://identifiers.org/pubmed/10970790
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_3a49c0ab_8c28_4c97_900d_f2df3a618680
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9dc715c7_2f07_46a5_ac92_52a9775c2bfe
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c019c563_abfd_4b8e_8dbd_50a724309e8d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a6a3fd40_31d2_4643_b0a7_c2e97f8110da
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5a14080a_f6aa_4a56_bbd1_bcfe089ad101
value: 0.0
type: LocalParameter

metaR ANTHte
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000185
fast: false
reversible: true
name: Transport of anthranilate
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_8ca3b269_4609_407d_91d9_b813c368f649
has only substance units: false
constant: false
initial amount: NaN
is: Q9P0L2
is encoded by: hsa:4139
is: SBO:0000252
boundary condition: true
type: Species
initial concentration: NaN
name: MARK1

http://identifiers.org/biomodels.db/MODEL1109130000#_f0f3d244_fab8_4c9c_9dd1_559449b4d398
is: Q13423
initial amount: NaN
is: SBO:0000252
name: NNT
constant: false
is encoded by: hsa:23530
boundary condition: true
type: Species
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_7ab5be9a_7e86_43e7_a4d8_e2b601bd16dd
has only substance units: false
type: Species
name: MLL3
is: SBO:0000252
constant: false
is encoded by: hsa:58508
boundary condition: true
initial amount: NaN
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_35fbede4_e5ea_46ea_bc58_feb152e42e55
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_91e7caee_e9e0_46af_9052_ed659c618852
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aca6fd52_d344_4940_9fda_fef4c651a24a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b27251f4_c769_4c2e_b034_12a95ecee34c
value: -1000.0
type: LocalParameter

metaR THRSERNaEx
reactant: MODEL1109130000#
name: L-serine/L-threonine Na-dependent exchange (Thr-L in)
fast: false
is version of: ECO:0000269
is: SBO:0000185
type: Reaction
is described by: http://identifiers.org/pubmed/14530974
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (6509.1) or (6510.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:14530974 NOTES: SAB see Kanai and Hediger 2004 (2003), PMID 14530974
reversible: false
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_4b8ba9ff_6ce2_4755_b92d_d170d4e7fa53
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#daff56c4_7335_4e3b_99d5_c9863995efa4
value: 1000.0
type: LocalParameter

metaR GLCtg
fast: false
notes: GENE_ASSOCIATION: 6513.1 SUBSYSTEM: Transport, golgi apparatus EC Number: Confidence Level: 4 AUTHORS: PMID:15384581 NOTES: NCD
product: MODEL1109130000#
modifier: MODEL1109130000#
name: glucose transport, Golgi apparatus
type: Reaction
is described by: http://identifiers.org/pubmed/15384581
is version of: ECO:0000269
is: SBO:0000185
reversible: true
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_61771866_122a_49a4_8320_faf25651abc5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_46d64cd7_ad9e_41c6_8211_693a84e14747
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e460ac62_f6bb_48ab_bc13_c7ffec0bf0a0
units: dimensionless
value: 0.0
type: LocalParameter

metaM hs deg5 l
boundary condition: false
initial concentration: 1.0
initial amount: NaN
constant: false
has only substance units: false
notes: FORMULA: C67H97N4O86S10 CHARGE: -11 INCHI:
name: heparan sulfate, degradation product 5
is: SBO:0000247
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_3ee5ad76_4592_43f1_867f_14ccc7be4ece
constant: true
boundary condition: true
name: DUT
is encoded by: hsa:1854
type: Species
is: P33316
initial concentration: NaN
initial amount: NaN
is: SBO:0000252
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_08275420_8c95_474a_9b0d_1ac485efc25a
initial concentration: NaN
boundary condition: true
has only substance units: false
constant: true
initial amount: NaN
is encoded by: hsa:8528
type: Species
is: Q99489
is: SBO:0000252
name: DDO

http://identifiers.org/biomodels.db/MODEL1109130000#_83621c7c_789a_44fd_9d80_244e9364fc60
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0f58db45_8aa9_4991_95f2_3f06011aa4c0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4caeef62_e991_4715_b70d_1a029b945db5
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74369b63_a51a_4f31_88a7_31804c430af1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7ef603a1_64fd_4a53_8a9c_3e30875cf096
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bfbbaf7f_4873_4a32_930d_4705e8a88792
value: -1000.0
type: LocalParameter

metaM CE1272 c
is: SBO:0000247
initial amount: NaN
name: 5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol
initial concentration: 1.0
has only substance units: false
notes: FORMULA: C27H48O4 CHARGE: 0 INCHI: InChI=1/C27H48O4/c1-16(7-6-11-25(2,3)31)19-8-9-20-24-21(15-23(30)27(19,20)5)26(4)12-10-18(28)13-17(26)14-22(24)29/h16-24,28-31H,6-15H2,1-5H3/t16-,17?,18?,19-,20+,21+,22+,23?,24+,26+,27-/m1/s1 EHMN_ABBREVIATION: CE1272
is: HMDB00655
type: Species
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_118e5738_49c5_46c8_adc5_8d220d2565f9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c6db41d7_7f7c_47ea_9e4c_de1f27c1a069
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d2a2ad3f_efe2_4cae_bb30_4265a4c26f64
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4cac69de_b885_4cd6_9058_6d4356dbfd25
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33a3b643_1c35_4299_9cc3_7419a0de466a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a2de19a4_6df2_4dd2_abd3_9edcc79b7093
units: dimensionless
value: 0.0
type: LocalParameter

metaM na1 r
name: sodium(1+)
constant: false
has only substance units: false
is: HMDB00588
initial concentration: 1.0
initial amount: NaN
boundary condition: false
notes: FORMULA: Na CHARGE: 1 INCHI: InChI=1S/Na/q+1 HEPATONET_1.0_ABBREVIATION: HC00763 EHMN_ABBREVIATION: C01330
is: CHEBI:29101
type: Species
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_91b4ac7b_34ad_41a9_94bb_8cddbcd4f8fd
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_43adda38_0694_4a46_8f73_93076bc59e70
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e7ac675f_0cc8_4af1_b6ee_7f67cca14ef1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_61065522_0434_42c9_9a2a_b1bf93b0f294
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_89b17c92_1c5d_4a58_b14f_1e6b0ecb768d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cb596453_5c64_4d6f_8ee2_74eb0436d93c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ee7d4927_8bf7_4305_b28a_1eb246617bbf
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ef6bef2b_7442_4c42_95f2_7de91acea008
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a9944ab9_4eb9_45ea_8bc6_aac2d308ec0d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7eae1ca7_3e4c_4a66_8185_a38beecfc60d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8d1defb4_762f_4dce_addb_a394b2993719
value: 0.0
type: LocalParameter

metaR GCHOLAtx
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 2 AUTHORS: NOTES: unknown mechanism, however bile acids need to be secreted out of the cell NJ
product: MODEL1109130000#
is version of: ECO:0000000
is: SBO:0000185
type: Reaction
fast: false
reactant: MODEL1109130000#
name: bile acid intracellular transport

http://identifiers.org/biomodels.db/MODEL1109130000#_94f935d9_0b70_41ac_b0c1_c452a8fb0356
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE1102 x
initial concentration: 1.0
is: SBO:0000247
name: cis-(3S)-hydroxytetradec-7-enoyl-CoA
type: Species
initial amount: NaN
notes: FORMULA: C35H56N7O18P3S CHARGE: -4 INCHI: HEPATONET_1.0_ABBREVIATION: HC11102 EHMN_ABBREVIATION: CE1102
constant: false
has only substance units: false
boundary condition: false

metaM CE4855 c
initial concentration: 1.0
type: Species
constant: false
is: SBO:0000247
notes: FORMULA: C45H70N7O17P3S CHARGE: -4 INCHI: InChI=1/C45H74N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-36(54)73-29-28-47-35(53)26-27-48-43(57)40(56)45(2,3)31-66-72(63,64)69-71(61,62)65-30-34-39(68-70(58,59)60)38(55)44(67-34)52-33-51-37-41(46)49-32-50-42(37)52/h5-6,8-9,11-12,14-15,32-34,38-40,44,55-56H,4,7,10,13,16-31H2,1-3H3,(H,47,53)(H,48,57)(H,61,62)(H,63,64)(H2,46,49,50)(H2,58,59,60)/p-4/b6-5-,9-8-,12-11-,15-14-/t34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4855
name: all-cis-12,15,18,21-tetracosatetraenoyl-CoA
has only substance units: false
initial amount: NaN
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_631ccc38_b794_40f8_a1c4_0ea7bb047874
name: CPA2
initial concentration: NaN
is: P48052
initial amount: NaN
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
is encoded by: hsa:1358
type: Species

metaR SUCRe
reversible: false
name: sucrose hydrolyzing enxyme, extracellular
fast: false
notes: GENE_ASSOCIATION: (6476.1) or (8972.1) SUBSYSTEM: Galactose metabolism EC Number: 3.2.1.26 Confidence Level: 4 AUTHORS: PMID:1560017,PMID:3143729 NOTES: NCD
is described by: http://identifiers.org/pubmed/3143729
is: SBO:0000176
is described by: http://identifiers.org/pubmed/1560017
is version of: http://identifiers.org/ec-code/3.2.1.26
is version of: ECO:0000269
reactant: MODEL1109130000#
product: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#f5769c00_428c_4844_9869_27455b2b159f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9cfc86ac_2593_4b49_aec7_336840df84fc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#af10d7c3_6abd_4c6b_856e_48ea653cb4af
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0240c219_99c4_425e_a04b_71dea0058074
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a476ecc8_3404_4a70_b5ad_7bd138b3334c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d759fdf1_321e_4765_84e2_eb0f0c4a620c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_36a4198c_a63a_4c4c_b459_bc2b683eefeb
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_6b21031d_ea74_4405_810a_2c6a2698787e
name: SLC15A1
is: SBO:0000252
is: B2CQT6
type: Species
initial amount: NaN
is encoded by: hsa:6564
boundary condition: true
constant: true
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_654d754a_175f_4f37_b803_8adb48a36b64
value: 0.0
type: LocalParameter

metaR DOLPMT L
notes: GENE_ASSOCIATION: (54344.2 and 8818.1 and 8813.1) or (8818.2 and 54344.1 and 8813.1) or (8818.1 and 54344.1 and 8813.1) or (54344.2 and 8818.2 and 8813.1) SUBSYSTEM: N-glycan synthesis EC Number: 2.4.1.83 Confidence Level: 0 AUTHORS: PMID:11420690 NOTES: NCD
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is version of: ECO:0000000
name: Dolichyl-phosphate D-mannosyltransferase (liver)
is described by: http://identifiers.org/pubmed/11420690
fast: false
reversible: false
type: Reaction
is: SBO:0000176
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.83

metaM CE2953 r
constant: false
notes: FORMULA: C20H27O3 CHARGE: -1 INCHI: InChI=1/C20H28O3/c1-15(8-6-9-16(2)14-17(21)22)10-13-20-18(3,4)11-7-12-19(20,5)23-20/h6,8-10,13-14H,7,11-12H2,1-5H3,(H,21,22)/p-1/b9-6+,13-10+,15-8+,16-14+ EHMN_ABBREVIATION: CE2953
is: SBO:0000247
has only substance units: false
name: rac-5,6-epoxy-retinoate
type: Species
boundary condition: false
initial amount: NaN
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_5f5b6bfe_02c1_4561_a268_3021d18f3cb9
has only substance units: false
type: Species
name: DBT
initial concentration: NaN
is encoded by: hsa:1629
is: P11182
initial amount: NaN
constant: true
boundary condition: true
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#a2f6973f_53b6_4bb1_b9b5_10d117f3fe0f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5bf1d108_406d_4880_b2a1_0c7db55c9574
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d0a44a65_0e6c_4672_8fee_f83f9069f224
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_27cd37e8_3874_41fd_8e91_6b3ac4c017b2
is encoded by: hsa:55191
initial amount: NaN
is: Q6IA69
has only substance units: false
type: Species
initial concentration: NaN
boundary condition: true
name: NADSYN1
constant: false
is: SBO:0000252
notes: DRUGBANK_SUBSTRATE: DB00130 DRUGBANK_UNKNOWN: DB00142

http://identifiers.org/biomodels.db/MODEL1109130000#_706246b0_8d0b_45d4_9095_0036730b8f20
value: 0.0
type: LocalParameter

metaR EX biocyt LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Biocytin exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#b6e12090_53db_4ae7_b8eb_46a9e0396789
units: dimensionless
value: 0.0
type: LocalParameter

metaR OIVD2m
reversible: false
type: Reaction
is described by: http://identifiers.org/pubmed/1429740
is described by: http://identifiers.org/pubmed/2914958
notes: GENE_ASSOCIATION: (1629.1) and (594.1 and 593.1) and (1738.1) or (1629.1) and (1738.1) and (594.2 and 593.1) SUBSYSTEM: Valine, leucine, and isoleucine metabolism EC Number: 1.8.1.4 Confidence Level: 4 AUTHORS: PMID:1429740,PMID:2914958 NOTES:
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.8.1.4
reactant: MODEL1109130000#
is version of: ECO:0000269
fast: false
product: MODEL1109130000#
is: SBO:0000176
name: 2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate), mitochondrial

http://identifiers.org/biomodels.db/MODEL1109130000#_88c0812e_28d2_4b3c_bfb0_02f0200e90a4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b7af4cb_a582_4b05_9d2c_6a13ebd0115d
value: 0.0
type: LocalParameter

metaM CE5244 c
boundary condition: false
constant: false
name: 4-hydroxyestrone-2-S-glutathione
is: SBO:0000247
initial amount: NaN
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: InChI=1/C28H37N3O9S/c1-28-9-8-13-14(17(28)4-6-21(28)32)2-3-15-16(13)10-20(25(37)24(15)36)41-12-19(26(38)30-11-23(34)35)31-22(33)7-5-18(29)27(39)40/h10,13-14,17-19,36-37H,2-9,11-12,29H2,1H3,(H,30,38)(H,31,33)(H,34,35)(H,39,40)/p-1/t13-,14+,17-,18+,19+,28+/m0/s1 EHMN_ABBREVIATION: CE5244
type: Species
initial concentration: 1.0
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3f1c7cfe_abfe_4b3d_8d60_04ef44a01885
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9e11ff23_34d6_411c_9985_22d1a7949ebd
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18dec381_c1c6_409a_8ce5_5223be44fc34
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d8cebb75_4799_4691_bcff_c4fd94b0a2f3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8eddb67c_f501_4dd8_8261_8fcbc92f1608
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bef215a9_959c_4f70_af39_22f44cdc9c08
value: 1000.0
type: LocalParameter

metaM na1 x
is: CHEBI:29101
is: HMDB00588
notes: FORMULA: Na CHARGE: 1 INCHI: InChI=1S/Na/q+1 HEPATONET_1.0_ABBREVIATION: HC00763 EHMN_ABBREVIATION: C01330
boundary condition: false
type: Species
initial concentration: 1.0
constant: false
has only substance units: false
is: SBO:0000247
name: sodium(1+)
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_6ea417d2_f023_4e82_af99_71d5719e22aa
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3ab92244_e2a1_4a65_872b_7ffdadd28e55
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC02195 c
initial concentration: 1.0
has only substance units: false
is: SBO:0000247
boundary condition: false
constant: false
name: tauroursodeoxycholate
initial amount: NaN
notes: FORMULA: CHARGE: 0 INCHI:
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#df73559a_64a8_4d49_868f_c863680d5d4b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_07170f25_aa2f_489a_ad97_cb0f1b81b16f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0bd14ff2_313b_484c_bbdc_f985f11f136a
initial concentration: NaN
is encoded by: hsa:27068
initial amount: NaN
boundary condition: true
constant: true
is: SBO:0000252
has only substance units: false
name: PPA2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_71ef5c92_0ce9_4bf5_9b8e_d038f174da57
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_93ec93e0_f5c2_4c53_a435_1621fb185057
value: 0.0
type: LocalParameter

metaR MGCHrm
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#
is version of: ECO:0000269
reversible: true
modifier: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/12434311
name: methylglutaconyl-CoA hydratase (reversible), mitochondrial
is version of: http://identifiers.org/ec-code/4.2.1.18
notes: GENE_ASSOCIATION: 549.1 SUBSYSTEM: Valine, leucine, and isoleucine metabolism EC Number: 4.2.1.18 Confidence Level: 4 AUTHORS: PMID:12434311,PMID:3082934 NOTES: MM
is: SBO:0000176
is described by: http://identifiers.org/pubmed/3082934

metaM CE5945 r
is: SBO:0000247
type: Species
notes: FORMULA: C20H33O6 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5945
name: 10,11-dihydro-20-dihydroxy-LTB4
initial amount: NaN
has only substance units: false
initial concentration: 1.0
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#a9cf9cc9_9684_4495_b779_84abc2ad5ff3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7aafc1ca_7cf9_4388_961b_740381580a30
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_759dfde5_12fa_49e5_81c5_afdcd8472952
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_25898334_c3a2_4712_9d42_4a5d06f67205
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a2b8ac9c_90ba_4525_8b93_8ca51412b212
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_01261638_ce24_49e6_a73c_99fb5b6e48f8
value: 0.0
type: LocalParameter

metaM 2mop c
is: SBO:0000247
initial concentration: 1.0
notes: FORMULA: C4H5O3 CHARGE: -1 INCHI: InChI=1S/C4H6O3/c1-3(2-5)4(6)7/h2-3H,1H3,(H,6,7)/p-1 HEPATONET_1.0_ABBREVIATION: HC00296 EHMN_ABBREVIATION: C00349
boundary condition: false
has only substance units: false
name: 2-methyl-3-oxopropanoate
is: HMDB01172
is: CHEBI:57700
constant: false
type: Species
initial amount: NaN

metaR ACOAD1fm
is: SBO:0000176
type: Reaction
name: acyl-CoA dehydrogenase (butanoyl-CoA), mitochondrial
notes: GENE_ASSOCIATION: (80724.1) or (36.1) or (35.1) or (34.1) or (84129.1) or (27034.1) or (28976.1) SUBSYSTEM: Butanoate metabolism EC Number: 1.3.99.2 Confidence Level: 4 AUTHORS: PMID:2565344 NOTES: Assume NAD/NADH as acceptors Lumped long-chain acyl-CoA dehydrogenase (EC 1.3.99.13) This reaction is therefore equilivalent to trans-2-enoyl-CoA reductase (NAD) (EC 1.3.1.44)
reversible: false
product: MODEL1109130000#
modifier: MODEL1109130000#
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/2565344
is version of: http://identifiers.org/ec-code/1.3.99.2
fast: false
reactant: MODEL1109130000#

metaR HBZOPT10m
is described by: http://identifiers.org/pubmed/1965190
is: SBO:0000176
notes: GENE_ASSOCIATION: 27235.1 SUBSYSTEM: Ubiquinone synthesis EC Number: Confidence Level: 4 AUTHORS: PMID:15153069,PMID:1965190,PMID:7380842 NOTES: Used to make Ubiquinone-10 EC 2.5.1.- IT
is described by: http://identifiers.org/pubmed/7380842
is version of: ECO:0000269
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15153069
reversible: false
name: Hydroxybenzoate Decaprenyltransferase
fast: false
product: MODEL1109130000#
type: Reaction

metaM tdchola c
name: taurochenodeoxycholate
has only substance units: false
boundary condition: false
type: Species
is: HMDB00951
is: SBO:0000247
initial amount: NaN
constant: false
is: CHEBI:9407
notes: FORMULA: C26H45NO6S CHARGE: 0 INCHI: InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22-,24+,25+,26-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC01471 EHMN_ABBREVIATION: C05465
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#ed1b1a81_1295_4d8f_a358_c596323b5be4
units: dimensionless
value: 0.0
type: LocalParameter

metaM tdchola e
notes: FORMULA: C26H45NO6S CHARGE: 0 INCHI: InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22-,24+,25+,26-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC01471 EHMN_ABBREVIATION: C05465
type: Species
has only substance units: false
constant: false
is: SBO:0000247
initial amount: NaN
initial concentration: 1.0
boundary condition: false
name: taurochenodeoxycholate
is: HMDB00951
is: CHEBI:9407

http://identifiers.org/biomodels.db/MODEL1109130000#_8d2cefa4_80e1_4a13_8ddd_72d1ffe2770e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_241a5cbc_1b86_4470_9ac6_159644a3687f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c32c3def_3e55_42a5_a32e_3790211cd5a9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a4054a45_fdda_4a28_a49b_4feaa17c292a
value: 0.0
type: LocalParameter

metaR RE2152C
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:9647871 NOTES:
product: MODEL1109130000#
is: SBO:0000176
reversible: true
fast: false
type: Reaction
reactant: MODEL1109130000#
name: RE2152
is described by: http://identifiers.org/pubmed/9647871

http://identifiers.org/biomodels.db/MODEL1109130000#_8fa69be7_2087_402e_a3c5_928acb4391c2
value: 0.0
type: LocalParameter

metaR DPGase
reversible: false
is: SBO:0000176
product: MODEL1109130000#
type: Reaction
name: Diphosphoglycerate phosphatase
is described by: http://identifiers.org/pubmed/17052986
is version of: ECO:0000134
is described by: http://identifiers.org/pubmed/15949708
notes: GENE_ASSOCIATION: (669.2) or (5223.1) or (5224.2) or (5224.1) or (669.1) SUBSYSTEM: Glycolysis/gluconeogenesis EC Number: 5.4.2.4 Confidence Level: 0 AUTHORS: PMID:15949708,PMID:17052986 NOTES: added EC num; also EC 5.4.2.4 -- NCD
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/5.4.2.4
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_56316626_456f_438e_b770_658e889c57ef
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cfeb4468_0a50_44d0_8b7e_bf1262dc7ad5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ecdf2b89_0dfd_40f9_bd2e_9f1d17938a43
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_59f4ecfb_50d2_4c95_925c_ba5c3af69a78
units: dimensionless
value: 0.0
type: LocalParameter

metaM 2mop m
initial concentration: 1.0
notes: FORMULA: C4H5O3 CHARGE: -1 INCHI: InChI=1S/C4H6O3/c1-3(2-5)4(6)7/h2-3H,1H3,(H,6,7)/p-1 HEPATONET_1.0_ABBREVIATION: HC00296 EHMN_ABBREVIATION: C00349
name: 2-methyl-3-oxopropanoate
is: HMDB01172
initial amount: NaN
boundary condition: false
type: Species
is: CHEBI:57700
is: SBO:0000247
has only substance units: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_09d8a7ae_5873_4295_90c4_447f465dc3a0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dc7d9fde_5ce0_43f9_aeed_bc736033a641
value: -1000.0
type: LocalParameter

metaM dcyt l
initial amount: NaN
is: SBO:0000247
initial concentration: 1.0
notes: FORMULA: C9H13N3O4 CHARGE: 0 INCHI: InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00574 EHMN_ABBREVIATION: C00881
is: CHEBI:15698
type: Species
constant: false
has only substance units: false
is: HMDB00014
boundary condition: false
name: 2-deoxycytidine

http://identifiers.org/biomodels.db/MODEL1109130000#_97227007_50c1_4660_b678_5c2ba92304c7
type: Species
has only substance units: false
initial concentration: NaN
name: AK2
initial amount: NaN
is encoded by: hsa:204
constant: true
boundary condition: true
is: SBO:0000252
is: P54819

http://identifiers.org/biomodels.db/MODEL1109130000#_2b3520a1_a493_47b9_aa9c_6d5b435352ec
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_590c67d8_3b4f_4517_88e8_59e222d2e3d8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_95c24f0a_eb11_47cb_aab1_4e5c62b9c4b3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d9266dd3_fdf0_4e1a_bc04_523865015d26
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8cd108d7_1639_42ce_84f7_0f1cb2c3e60e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e38a4ee3_2951_45dc_975f_6c15ea69adc4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_839739a5_fd8e_486a_8184_231f52849fc4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0e67d378_004b_423a_9dde_0334c23129bf
units: dimensionless
value: 0.0
type: LocalParameter

metaM dcyt m
is: CHEBI:15698
has only substance units: false
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C9H13N3O4 CHARGE: 0 INCHI: InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00574 EHMN_ABBREVIATION: C00881
is: SBO:0000247
is: HMDB00014
type: Species
boundary condition: false
name: 2-deoxycytidine
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_417b74d2_87fd_425f_8747_5b4bb8468312
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9708d2f4_cd7d_43d3_b20a_5f5b64c1b701
initial concentration: NaN
has only substance units: false
is encoded by: hsa:205
initial amount: NaN
is: SBO:0000252
name: AK4
type: Species
boundary condition: true
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#c74a3851_1ac9_4347_ba3e_602937171323
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1G3:ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V1C1:ATP6V1E1:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_74825de9_d540_4935_b0d0_4ec6cafbf36c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cf0fda24_0635_45ca_8c40_6c4aa46ca26c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d5b37374_4bff_4ec8_9852_a1d2b6d78bab
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0fd7aed0_3f87_4cb3_a143_afd849f769ef
units: dimensionless
value: 0.0
type: LocalParameter

metaR PI45P3Kn
is version of: ECO:0000000
fast: false
is described by: http://identifiers.org/pubmed/12728269
is: SBO:0000176
reversible: false
name: phosphatidylinositol 4,5-bisphosphate 3-kinase, nuclear
is version of: http://identifiers.org/ec-code/2.7.1.153
type: Reaction
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol phosphate metabolism EC Number: 2.7.1.153 Confidence Level: 2 AUTHORS: PMID:12728269 NOTES: NCD
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#f798550b_2987_4c3b_af48_15afa78658cf
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3af95987_a48a_4c91_975c_fd1f4d25bc51
is: SBO:0000252
is encoded by: hsa:11282
initial concentration: NaN
name: MGAT4B
constant: false
initial amount: NaN
boundary condition: true
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#aea1e281_b710_4975_945e_27523329ded3
value: 0.0
type: LocalParameter

metaM dcyt n
initial concentration: 1.0
is: CHEBI:15698
type: Species
notes: FORMULA: C9H13N3O4 CHARGE: 0 INCHI: InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00574 EHMN_ABBREVIATION: C00881
constant: false
is: HMDB00014
boundary condition: false
name: 2-deoxycytidine
initial amount: NaN
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_2ba81da8_86fa_4728_b7a9_f88e53b04650
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a572b9db_52c2_4155_a98a_453a96abe861
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b1f5c0b_0af1_4a52_9b6c_b3a8818c253b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6e14ce18_ff94_4a03_866d_43bbcfd2e2ae
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_79ddc972_e4cd_4b2e_b185_1c2f4e393acf
value: 0.0
type: LocalParameter

metaM hs pre5 g
is: SBO:0000247
constant: false
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C59H89N3O47X CHARGE: -3 INCHI:
has only substance units: false
type: Species
name: (GlcNAc-GlcA)2-GlcNAc-GlcA-Gal-Gal-Xyl-L-Ser (protein)
boundary condition: false

metaR DOLPMT U
notes: GENE_ASSOCIATION: (54344.2 and 8818.1 and 8813.1) or (8818.2 and 54344.1 and 8813.1) or (8818.1 and 54344.1 and 8813.1) or (54344.2 and 8818.2 and 8813.1) SUBSYSTEM: N-glycan synthesis EC Number: 2.4.1.83 Confidence Level: 0 AUTHORS: PMID:11420690 NOTES: NCD
type: Reaction
modifier: MODEL1109130000#
is: SBO:0000176
name: Dolichyl-phosphate D-mannosyltransferase (uterus)
reversible: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11420690
fast: false
is version of: ECO:0000000
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.83

http://identifiers.org/biomodels.db/MODEL1109130000#_71cbec5d_f1c4_40f8_9393_1854f34d579d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4c7c52f5_fbe1_41e6_8049_7e8066de8544
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8177e495_3bae_41ee_8723_c58bd1527302
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f980c19f_9810_42d7_9967_c2444fe82013
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c5ba6531_0096_411b_9248_a41779db8bb1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0c522811_7e21_4784_beae_334a41207ffe
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC02195 e
constant: false
is: SBO:0000247
type: Species
name: tauroursodeoxycholate
initial amount: NaN
has only substance units: false
boundary condition: false
initial concentration: 1.0
notes: FORMULA: CHARGE: 0 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#e8d1f631_9f2e_439d_a2f8_a1ac24c03445
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a10fe6ce_19eb_473e_97f9_b2f11ff35e26
name: B4GALT7
initial amount: NaN
has only substance units: false
boundary condition: true
constant: true
type: Species
is: Q9UBV7
is encoded by: hsa:11285
initial concentration: NaN
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_9ae68cfe_4fbd_4c72_9d40_307a0674f7af
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#acad52ca_52b4_4fcc_a797_d0bbd5cbbac7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e336dd6c_940c_4acd_90a7_0b9da6b4a7ee
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69ea6840_5240_4f38_803a_3c8ddd73a3c1
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_12359857_fbbd_479f_8b3c_c86da5b46521
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0aa8828b_e7cd_42a7_a860_ce31f51c2c65
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6181b14d_e812_4990_96c5_94a4fa9f601f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_99f9af3b_4748_46bc_a3d1_84c76cf272e1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18b48af4_6c4e_46c7_a3ac_440878f62e3d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_718327f7_fad6_4b0b_9340_2b6ddc32769c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cc92d699_b3db_457e_9d7e_6f62b95d0191
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a4ab7f73_7807_48bb_b683_57f450d0df14
type: Species
constant: true
is: Q96KP4
initial concentration: NaN
boundary condition: true
initial amount: NaN
name: CNDP2
is encoded by: hsa:55748
is: SBO:0000252
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#b4fbb844_cb77_4837_8cd1_7aede6f7931a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8453a673_169d_4197_8c66_f979254b1120
type: Species
initial concentration: NaN
is encoded by: hsa:84532
boundary condition: true
initial amount: NaN
is: Q9NUB1
has only substance units: false
is: SBO:0000252
constant: false
name: ACSS1

metaR VITEtl
is: SBO:0000185
reactant: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/15213020
name: efflux of alpha-Tocopherol into the lyphatics in chylomicrons
fast: false
reversible: false
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 15213020, PMID: 17320165 EC Number: NOTES: ATP binding cassete required for efflux of the vitamin E into the lymph form the enterocytes. GENE_ASSOCIATION: 19.1
is described by: http://identifiers.org/pubmed/17320165
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_5472d718_8b87_49da_b5ab_8cad514a815a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_19fc1889_2dff_4628_9d17_4a6a85431d42
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1e727ff5_95ab_42ee_9314_c77fb7aa88d5
value: -1000.0
type: LocalParameter

metaR RE3103C
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
is described by: http://identifiers.org/pubmed/10970790
fast: false
product: MODEL1109130000#
is: SBO:0000176
name: RE3103
reversible: false

metaM 44mctr c
name: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
has only substance units: false
is: CHEBI:17813
notes: FORMULA: C29H46O CHARGE: 0 INCHI: InChI=1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC01808 EHMN_ABBREVIATION: C11455
boundary condition: false
initial concentration: 1.0
is: HMDB01023
is: SBO:0000247
constant: false
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#f40acb32_1e4b_4f6d_af74_3aeca5703474
value: 0.0
type: LocalParameter

metaR GLNTHRNaEx
fast: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 6510.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:14530974 NOTES: SAB see Kanai and Hediger 2004 (2003), PMID 14530974
type: Reaction
is described by: http://identifiers.org/pubmed/14530974
is version of: ECO:0000269
reactant: MODEL1109130000#
reversible: false
name: L-threonine/L-glutamine Na-dependent exchange (Gln-L in)
product: MODEL1109130000#
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#b0bc79b5_a6fd_44e9_a3fb_15a68c45677d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_56464caa_5aba_4460_aab6_17c60f51ea48
boundary condition: true
name: SOD1
has only substance units: false
is encoded by: hsa:6647
constant: false
initial concentration: NaN
initial amount: NaN
type: Species
is: P00441
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_3ae1b36d_1f8a_4499_b46e_3730789f6552
units: dimensionless
value: 0.0
type: LocalParameter

metaR FAOXC162C162OHm
is: SBO:0000176
fast: false
product: MODEL1109130000#
modifier: MODEL1109130000#
name: fatty acid beta oxidation(C16:2-->C16:2OH)m
reversible: false
reactant: MODEL1109130000#
type: Reaction
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 2 AUTHORS: PMID: 21281499 EC Number: NOTES: GENE_ASSOCIATION: (37.1 and 3030.1)
is described by: http://identifiers.org/pubmed/21281499

http://identifiers.org/biomodels.db/MODEL1109130000#ee8a1f22_47bf_4794_8383_8022ef83f0e1
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fc2daf58_866c_4f0e_bda8_720bab3b00b3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3a538083_fc74_4371_8f94_e34871b929d0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3ce35693_c43e_46c1_8fac_9c6cd1875b63
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c8363b8f_a7b6_4404_ba79_a6dbfdc91e81
value: 0.0
type: LocalParameter

metaR r0750
is: SBO:0000176
is described by: http://identifiers.org/pubmed/1591235
reversible: true
product: MODEL1109130000#
name: 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50
fast: false
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.1.1.50
reactant: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/3459552
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Bile acid synthesis EC Number: 1.1.1.50 Confidence Level: 0 AUTHORS: PMID:1591235,PMID:3459552 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#c9430bea_5a44_4986_b81a_6ae150afd47e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_36bc5a54_90d2_4f73_829a_c8d592d5a73b
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_942e06eb_f3b2_4f60_8b18_9a54dd90bef1
value: 1000.0
type: LocalParameter

metaM CE5244 m
initial amount: NaN
type: Species
name: 4-hydroxyestrone-2-S-glutathione
initial concentration: 1.0
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: InChI=1/C28H37N3O9S/c1-28-9-8-13-14(17(28)4-6-21(28)32)2-3-15-16(13)10-20(25(37)24(15)36)41-12-19(26(38)30-11-23(34)35)31-22(33)7-5-18(29)27(39)40/h10,13-14,17-19,36-37H,2-9,11-12,29H2,1H3,(H,30,38)(H,31,33)(H,34,35)(H,39,40)/p-1/t13-,14+,17-,18+,19+,28+/m0/s1 EHMN_ABBREVIATION: CE5244
is: SBO:0000247
boundary condition: false
has only substance units: false
constant: false

metaR EX xolest hs LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: cholesterol ester exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#dc8e90d8_d83b_40c9_b8a2_c247978383cf
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_faf346eb_1fe0_4f07_86f2_e0e4965d830e
type: Species
name: IDH3A:IDH3B:IDH3G
is: SBO:0000297
has only substance units: false
initial concentration: NaN
initial amount: NaN
has part: P50213
is encoded by: hsa:3419
has part: P51553
boundary condition: true
is encoded by: hsa:3420
constant: true
is encoded by: hsa:3421

http://identifiers.org/biomodels.db/MODEL1109130000#_3b8cf3d3_9f62_46af_bb81_2d5368e3d371
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17322db2_973e_431f_8729_7d50fe76fbfb
value: 0.0
type: LocalParameter

metaM CE0782 x
name: 3-oxomyrist-7-enoyl-CoA
has only substance units: false
type: Species
constant: false
initial amount: NaN
initial concentration: 1.0
boundary condition: false
is: SBO:0000247
notes: FORMULA: C35H54N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE0782

http://identifiers.org/biomodels.db/MODEL1109130000#_14b2f5c9_33e6_4c2c_ac2f_78a799bde726
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_36adfb44_8343_49fe_b8a5_87edd1425a70
boundary condition: true
has only substance units: false
type: Species
initial concentration: NaN
constant: true
is: SBO:0000252
initial amount: NaN
name: IP6K2
is encoded by: hsa:51447

http://identifiers.org/biomodels.db/MODEL1109130000#_929fb866_cb6f_42fc_b4d0_16c3b73bb107
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a1d6b7ab_4e4a_4c74_8737_7f98e6ad02dd
value: 0.0
type: LocalParameter

metaM pcreat m
notes: FORMULA: C4H9N3O5P CHARGE: -1 INCHI: InChI=1S/C4H10N3O5P/c1-7(2-3(8)9)4(5)6-13(10,11)12/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12)/p-2 EHMN_ABBREVIATION: C02305
is: CHEBI:58092
initial concentration: 1.0
has only substance units: false
initial amount: NaN
name: N-phosphocreatinate(2-)
is: SBO:0000247
constant: false
is: HMDB01511
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_6231a7ec_f189_416e_b0ba_371ab5173d84
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3f66f927_a5bc_40a4_9ebc_6b31e41eae7f
value: 0.0
type: LocalParameter

metaM pyr x
has only substance units: false
is: C00022
initial amount: NaN
is: SBO:0000247
is: CHEBI:15361
initial concentration: 1.0
is: HMDB00243
is: http://identifiers.org/pubchem.substance/3324
boundary condition: false
constant: false
name: pyruvate
type: Species
notes: FORMULA: C3H3O3 CHARGE: -1 HEPATONET_1.0_ABBREVIATION: HC00032 EHMN_ABBREVIATION: C00022 INCHI: InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/p-1

http://identifiers.org/biomodels.db/MODEL1109130000#_8512c63f_1e75_4c1c_a7ea_9e8d3d391e16
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b06691ca_fd07_425b_b7d3_9740bdfa40dc
type: Species
is: O75795
constant: true
initial amount: NaN
initial concentration: NaN
is encoded by: hsa:7367
is: SBO:0000252
boundary condition: true
has only substance units: false
name: UGT2B17

http://identifiers.org/biomodels.db/MODEL1109130000#e0aabaf8_e07c_4c9a_89fd_c329743b6a3b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_383b157e_4862_4208_bba8_e20f92a36c6c
value: 1000.0
type: LocalParameter

metaM glutcoa m
is: HMDB01339
has only substance units: false
is: SBO:0000247
name: glutaryl-CoA(5-)
boundary condition: false
type: Species
initial concentration: 1.0
is: CHEBI:57378
initial amount: NaN
notes: FORMULA: C26H37N7O19P3S CHARGE: -5 INCHI: InChI=1S/C26H42N7O19P3S/c1-26(2,21(39)24(40)29-7-6-15(34)28-8-9-56-17(37)5-3-4-16(35)36)11-49-55(46,47)52-54(44,45)48-10-14-20(51-53(41,42)43)19(38)25(50-14)33-13-32-18-22(27)30-12-31-23(18)33/h12-14,19-21,25,38-39H,3-11H2,1-2H3,(H,28,34)(H,29,40)(H,35,36)(H,44,45)(H,46,47)(H2,27,30,31)(H2,41,42,43)/p-5/t14-,19-,20-,21+,25-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00411 EHMN_ABBREVIATION: C00527
constant: false

metaR SERATB0tc
fast: false
is described by: http://identifiers.org/pubmed/18195088
modifier: MODEL1109130000#
type: Reaction
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID:18195088 EC Number: NOTES: ATB0 is both sodium and chloride coupled, with reaction stoichiometry 2Na+:1cl:1amino acid. The transporter is localted in the intestine, has a broad substrate specificity (both neutral and cationic amino acids), but is not involved in the transport of aspartate, glutamate and proline (PMID:18195088). GENE_ASSOCIATION: 11254.1
is: SBO:0000185
name: transport of L-Serine into the intestinal cells by ATB0 transporter
reversible: false
product: MODEL1109130000#
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_83c09948_96e5_4517_abd9_a62274b8d6e8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f8c02192_7202_4fb4_9258_33f72370aa55
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d440e669_7c0c_4111_9cdb_80bb1fe5604c
value: 1000.0
type: LocalParameter

metaR GCHOLAte
reactant: MODEL1109130000#
fast: false
type: Reaction
product: MODEL1109130000#
is: SBO:0000185
is version of: ECO:0000000
name: bile acid intracellular transport
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES: unknown mechanism, however bile acids need to be secreted out of the cell NJ

http://identifiers.org/biomodels.db/MODEL1109130000#e388e9d4_6758_42bc_9190_95068eeff036
value: -1000.0
type: LocalParameter

metaR TRIODTHYSULT
fast: false
type: Reaction
is version of: ECO:0000269
reversible: false
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15293241
notes: GENE_ASSOCIATION: (6817.4) or (6817.1) or (6817.3) or (6817.2) or (6817.5) SUBSYSTEM: Tyrosine metabolism EC Number: 2.8.2.1 Confidence Level: 4 AUTHORS: PMID:11535246,PMID:15293241 NOTES: RS/TV (6/14/05)
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.8.2.1
is described by: http://identifiers.org/pubmed/11535246
name: Triiodothyronine Sulfotransferase
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_508f3fd9_d9e3_4f26_9187_b24360b957de
initial concentration: NaN
notes: DRUGBANK_UNKNOWN: DB00157, DB01907, DB02483, DB02701, DB03940
is encoded by: hsa:3939
has only substance units: false
is: SBO:0000252
type: Species
constant: false
name: LDHA
is: P00338
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_609f592d_7323_48c0_b269_117a515b91a5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#afab4a5b_46cc_4b61_ae07_e0f70284a4ba
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b03217d_81d1_45eb_87dc_a0d28ccbbb99
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_27f6f3f4_7b63_43ff_80b2_d018abbc46f3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_51052253_24ba_4f8f_9c07_5189436b057d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_02a9eca1_77ea_4478_870e_049650efe827
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f82ca842_e135_4724_8565_80a60e5d7cc1
value: 0.0
type: LocalParameter

metaR r0730
is described by: http://identifiers.org/pubmed/8188243
type: Reaction
is described by: http://identifiers.org/pubmed/10329704
fast: false
is described by: http://identifiers.org/pubmed/7150615
is version of: http://identifiers.org/ec-code/1.1.1.211
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1651711
modifier: MODEL1109130000#
is: SBO:0000176
reversible: false
is described by: http://identifiers.org/pubmed/10231530
is described by: http://identifiers.org/pubmed/8687463
name: (S)-Hydroxyoctanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211
is described by: http://identifiers.org/pubmed/1550553
notes: GENE_ASSOCIATION: 34.1 SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.211 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9553139

http://identifiers.org/biomodels.db/MODEL1109130000#_243378c2_32ed_426b_bce7_4b09d0087715
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_28823af6_1b8d_46e3_8cb4_bfe92631db09
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d6e74112_8757_4f1a_b39d_6a6a2ecc0343
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2725671_15bb_4a29_81a2_ecde5292ba0a
units: dimensionless
value: 0.0
type: LocalParameter

metaM xoltri25 e
is: SBO:0000247
type: Species
initial amount: NaN
boundary condition: false
initial concentration: 1.0
name: 7alpha,25-dihydroxycholesterol
is: CHEBI:37623
notes: FORMULA: C27H46O3 CHARGE: 0 INCHI: InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23-,24+,26+,27-/m1/s1
has only substance units: false
is: HMDB06280
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_289e4a4e_8736_4747_8a50_a98aa6d1ff78
value: 1000.0
type: LocalParameter

metaR 1a 24 25VITD2Hm
is: SBO:0000176
fast: false
type: Reaction
is version of: ECO:0000134
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/6974773
name: 1-alpha-Vitamin D-24,25-hydroxylase (D2)
reactant: MODEL1109130000#
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin D metabolism EC Number: Confidence Level: 2 AUTHORS: PMID:6974773 NOTES:

metaR RE3220L
is version of: http://identifiers.org/ec-code/3.1.6.2
name: RE3220
type: Reaction
is described by: http://identifiers.org/pubmed/2969800
product: MODEL1109130000#
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is: SBO:0000176
fast: false
notes: GENE_ASSOCIATION: 412.1 SUBSYSTEM: Androgen and estrogen synthesis and metabolism EC Number: 3.1.6.2 Confidence Level: 0 AUTHORS: PMID:2969800 NOTES: IT - fixed proton
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_5177dd8b_2e4e_493f_bb98_54d73e447bb9
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4098b97a_39af_49b7_9761_25605517acea
value: 1000.0
type: LocalParameter

metaM HC00001 l
initial concentration: 1.0
boundary condition: false
type: Species
initial amount: NaN
notes: FORMULA: CHARGE: 0
name: Albumin
constant: false
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_6ed0317b_6415_43e6_9ed1_b93db788577d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3adbf583_40ca_4fb7_8a2d_3c53255fdaea
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7bc1f3fc_bc16_4a0f_a964_3d243fb65cd5
is: P36551
is: SBO:0000252
constant: false
initial amount: NaN
name: CPOX
type: Species
boundary condition: true
initial concentration: NaN
is encoded by: hsa:1371
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6bf977fe_4fde_43a4_a406_a2e3259038a5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_58ea47ce_3c51_4734_9f7a_2e16f057099b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_590fb262_9f2c_4554_9874_80fb3b5b03af
value: -1000.0
type: LocalParameter

metaR RE3220R
is version of: http://identifiers.org/ec-code/3.1.6.2
is described by: http://identifiers.org/pubmed/2969800
notes: GENE_ASSOCIATION: 412.1 SUBSYSTEM: Androgen and estrogen synthesis and metabolism EC Number: 3.1.6.2 Confidence Level: 0 AUTHORS: PMID:2969800 NOTES: IT - fixed proton
fast: false
name: RE3220
reversible: true
modifier: MODEL1109130000#
is: SBO:0000176
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_1115306b_01b5_44de_bfdd_5d72ca6e6c37
value: 0.0
type: LocalParameter

metaR HESTRATRIOLtr
name: hydroxylated estrogen derivative transport
is version of: ECO:0000000
is: SBO:0000185
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 0 AUTHORS: NOTES: unknown mechanism, hydroxylated (inactivated) estrogen derivative needs to be transported out of the cell NJ
reversible: true
reactant: MODEL1109130000#
type: Reaction
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#deea87eb_d606_442a_a2f5_8ad987c1dc2f
value: 0.0
type: LocalParameter

metaR EX HC01104 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Exchange of 4-nitrophenyl phosphate(2-)
type: Reaction

metaR r0733
notes: GENE_ASSOCIATION: 8659.1 SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
is described by: http://identifiers.org/pubmed/9553139
name: (S)-Hydroxyhexanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
is described by: http://identifiers.org/pubmed/10231530
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/1651711
fast: false
is described by: http://identifiers.org/pubmed/8687463
modifier: MODEL1109130000#
is: SBO:0000176
reversible: false
is described by: http://identifiers.org/pubmed/8188243
is described by: http://identifiers.org/pubmed/1550553
is described by: http://identifiers.org/pubmed/10329704
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7150615
is version of: http://identifiers.org/ec-code/1.1.1.35

http://identifiers.org/biomodels.db/MODEL1109130000#_91b5d28a_7ff3_4a34_a2a5_a855edcf425e
initial amount: NaN
boundary condition: true
is encoded by: hsa:59272
type: Species
name: ACE2
is: C7ECU1
is: SBO:0000252
has only substance units: false
constant: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_1c813cca_af9d_4635_969f_01c8b2cef515
value: 0.0
type: LocalParameter

metaM CE5547 c
constant: false
name: 5-S-glutathionyl-noradrenochrome hydroquinone
type: Species
initial concentration: 1.0
has only substance units: false
initial amount: NaN
is: SBO:0000247
boundary condition: false
notes: FORMULA: C18H23N4O9S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5547

http://identifiers.org/biomodels.db/MODEL1109130000#_610f89e3_aa2a_4f30_8dd6_63a740cc6790
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_703f075e_e8cf_4649_abe4_d35ab6876b96
name: HMGCS2
is: SBO:0000252
initial concentration: NaN
is encoded by: hsa:3158
has only substance units: false
is: P54868
boundary condition: true
initial amount: NaN
constant: false
type: Species

metaR r0734
reversible: false
product: MODEL1109130000#
type: Reaction
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
name: (S)-Hydroxyhexanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
is described by: http://identifiers.org/pubmed/8188243
is version of: http://identifiers.org/ec-code/4.2.1.17
is described by: http://identifiers.org/pubmed/8012501
reactant: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_987e3b5c_da35_4d0c_8fab_606a12b796bc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17c42913_769a_4d79_a82d_29845a5d1a42
value: -1000.0
type: LocalParameter

metaM CE5158 c
initial amount: NaN
notes: FORMULA: C45H74N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5158
type: Species
constant: false
name: trans,cis-2,15-tetracosadienoyl-CoA
boundary condition: false
has only substance units: false
initial concentration: 1.0
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_622ac13d_e31d_4eeb_99b8_d014d94f2b5a
units: dimensionless
value: 0.0
type: LocalParameter

metaR ACALDt
is: SBO:0000185
fast: false
product: MODEL1109130000#
name: acetaldehyde reversible transport
reversible: true
type: Reaction
is version of: ECO:0000000
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES: NCD

http://identifiers.org/biomodels.db/MODEL1109130000#_820f9d08_a26d_4cfc_b26a_9c3586d7be7e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ecd6416c_eef7_48ea_befe_b75b7f1acc8a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f02f4c54_2851_47e5_9d39_7e4bb547eafe
value: 1000.0
type: LocalParameter

metaM CE1102 c
constant: false
is: SBO:0000247
has only substance units: false
initial amount: NaN
boundary condition: false
initial concentration: 1.0
name: cis-(3S)-hydroxytetradec-7-enoyl-CoA
notes: FORMULA: C35H56N7O18P3S CHARGE: -4 INCHI: HEPATONET_1.0_ABBREVIATION: HC11102 EHMN_ABBREVIATION: CE1102
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_40ab2249_4b86_43ae_a93c_ff91de409f41
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_04bd035a_4f8c_47bd_b92b_314eb6fba41e
units: dimensionless
value: 0.0
type: LocalParameter

metaR GAMYe
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.2.1.3
is version of: ECO:0000000
notes: GENE_ASSOCIATION: 8972.1 SUBSYSTEM: Starch and sucrose metabolism EC Number: 3.2.1.3 Confidence Level: 4 AUTHORS: PMID:3143729 NOTES: NCD
reversible: false
is: SBO:0000176
is described by: http://identifiers.org/pubmed/3143729
fast: false
type: Reaction
product: MODEL1109130000#
name: glucoamylase, extracellular (glygn5 -> malt)

http://identifiers.org/biomodels.db/MODEL1109130000#_2788a8f7_f227_4d4b_9faf_08a7470f71bd
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0731
is described by: http://identifiers.org/pubmed/8012501
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
reversible: false
type: Reaction
is version of: http://identifiers.org/ec-code/4.2.1.17
is: SBO:0000176
name: (S)-Hydroxyoctanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
is described by: http://identifiers.org/pubmed/8188243

http://identifiers.org/biomodels.db/MODEL1109130000#ea236d0d_8b26_4179_9d91_266681cc2fa6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_06d08153_4140_43fc_afce_a8182d5b3caf
value: 1000.0
type: LocalParameter

metaM pcreat c
has only substance units: false
is: HMDB01511
notes: FORMULA: C4H9N3O5P CHARGE: -1 INCHI: InChI=1S/C4H10N3O5P/c1-7(2-3(8)9)4(5)6-13(10,11)12/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12)/p-2 EHMN_ABBREVIATION: C02305
boundary condition: false
is: SBO:0000247
initial concentration: 1.0
is: CHEBI:58092
constant: false
name: N-phosphocreatinate(2-)
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_2ab6cd86_2c1e_4be9_aaa3_80c1088661ff
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17bb2516_bb8f_4d71_94e1_d64ec31790b6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b68ecc03_59d2_49f6_8497_1a676bf3e96f
value: 0.0
type: LocalParameter

metaM 4ppcys c
initial concentration: 1.0
initial amount: NaN
constant: false
has only substance units: false
type: Species
is: C04352
is: CHEBI:59458
name: N-((R)-4-Phosphopantothenoyl)-L-cysteine
boundary condition: false
is: HMDB01117
is: SBO:0000247
notes: FORMULA: C12H20N2O9PS CHARGE: -3 HEPATONET_1.0_ABBREVIATION: HC01276 EHMN_ABBREVIATION: C04352 INCHI: InChI=1S/C12H23N2O9PS/c1-12(2,6-23-24(20,21)22)9(16)10(17)13-4-3-8(15)14-7(5-25)11(18)19/h7,9,16,25H,3-6H2,1-2H3,(H,13,17)(H,14,15)(H,18,19)(H2,20,21,22)/p-3/t7-,9-/m0/s1

metaM xoltri25 c
initial concentration: 1.0
has only substance units: false
type: Species
name: 7alpha,25-dihydroxycholesterol
is: HMDB06280
notes: FORMULA: C27H46O3 CHARGE: 0 INCHI: InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23-,24+,26+,27-/m1/s1
initial amount: NaN
is: CHEBI:37623
constant: false
is: SBO:0000247
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_2a138638_0cd3_4460_b1e5_efb760f79c55
value: 1000.0
type: LocalParameter

metaR C2tcx
reversible: true
modifier: MODEL1109130000#
fast: false
type: Reaction
is: SBO:0000185
reactant: MODEL1109130000#
product: MODEL1109130000#
name: transport of acetylcarnitine from peroxisomes to cytosol
notes: SUBSYSTEM: Transport, peroxisomal Confidence Level: 4 AUTHORS: biochemical and biophysical research communications 263,213-218(1999),biochimica et biophysica acta 1546(2001)21-43 EC Number: NOTES: GENE_ASSOCIATION: 788.1

metaM CE1279 c
constant: false
initial amount: NaN
initial concentration: 1.0
is: HMDB00556
boundary condition: false
has only substance units: false
notes: FORMULA: C27H48O5 CHARGE: 0 INCHI: InChI=1/C27H48O5/c1-15(6-9-22(30)25(2,3)32)18-7-8-19-24-20(14-23(31)27(18,19)5)26(4)11-10-17(28)12-16(26)13-21(24)29/h15-24,28-32H,6-14H2,1-5H3/t15-,16?,17-,18-,19+,20+,21-,22?,23+,24+,26+,27-/m1/s1 EHMN_ABBREVIATION: CE1279
type: Species
is: SBO:0000247
name: 5beta-cholestane-3alpha,7alpha,12alpha,24R,25-pentol

http://identifiers.org/biomodels.db/MODEL1109130000#_211f4bb9_da23_44f3_95b9_3fccd5a4043e
value: 1000.0
type: LocalParameter

metaR r0732
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.16 Confidence Level: 0 AUTHORS: PMID:1121274,PMID:1679347,PMID:3194209,PMID:6378901,PMID:8241273 NOTES:
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.16
is described by: http://identifiers.org/pubmed/1121274
is described by: http://identifiers.org/pubmed/1679347
is described by: http://identifiers.org/pubmed/3194209
type: Reaction
is: SBO:0000176
is described by: http://identifiers.org/pubmed/6378901
is described by: http://identifiers.org/pubmed/8241273
name: Hexanoyl-CoA:acetyl-CoA C-acyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
reactant: MODEL1109130000#
fast: false
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_7f4e23d1_f4ba_4dab_b808_e725c01e327f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ab91dc44_2cf6_43e3_a5cd_10bd3b55bfc8
value: 1000.0
type: LocalParameter

metaR EX adrn LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: adrenic acid exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_7f570696_62b9_40bd_a268_ccf15dcdfd99
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_07eeca6e_2bd4_456d_8346_b28083024fbf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_97f5d3a4_52e8_416e_980a_c5ef4a839b11
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#df710d74_5f49_4cbf_a9ca_1bb3692fb02b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_84e6b76d_9416_4bb1_97b7_25f313a8b601
value: 1000.0
type: LocalParameter

metaR r0737
is described by: http://identifiers.org/pubmed/3109378
name: 3-Ketolactose galactohydrolase Galactose metabolism EC:3.2.1.23
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Unassigned EC Number: 3.2.1.23 Confidence Level: 0 AUTHORS: PMID:3109378 NOTES:
type: Reaction
reversible: true
product: MODEL1109130000#
reactant: MODEL1109130000#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/3.2.1.23
fast: false
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_39523ad6_abc4_4536_9f17_f55c9380ae6f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2edaefe5_b86f_4ede_a143_6e94f5f9674d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_566a1729_bdd7_4f49_a122_450cd5e6f0f6
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_30146f6f_a0ed_4730_a656_75a5e1a85f50
value: 0.0
type: LocalParameter

metaM HC00001 c
constant: false
initial concentration: 1.0
name: Albumin
has only substance units: false
boundary condition: false
type: Species
notes: FORMULA: CHARGE: 0
is: SBO:0000247
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_8097e504_c580_4689_9742_b5c9af40320d
value: 1000.0
type: LocalParameter

metaM CE1279 r
type: Species
name: 5beta-cholestane-3alpha,7alpha,12alpha,24R,25-pentol
has only substance units: false
initial amount: NaN
notes: FORMULA: C27H48O5 CHARGE: 0 INCHI: InChI=1/C27H48O5/c1-15(6-9-22(30)25(2,3)32)18-7-8-19-24-20(14-23(31)27(18,19)5)26(4)11-10-17(28)12-16(26)13-21(24)29/h15-24,28-32H,6-14H2,1-5H3/t15-,16?,17-,18-,19+,20+,21-,22?,23+,24+,26+,27-/m1/s1 EHMN_ABBREVIATION: CE1279
constant: false
initial concentration: 1.0
boundary condition: false
is: HMDB00556
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_c97125cc_3b69_4d25_afcd_70b1818580c5
is: P35575
type: Species
initial concentration: NaN
boundary condition: true
has only substance units: false
initial amount: NaN
constant: true
is: SBO:0000252
is encoded by: hsa:2538
name: G6PC

http://identifiers.org/biomodels.db/MODEL1109130000#_8c30a31f_1b82_460a_9ae6_e5ed4ef9d632
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1269b2c1_026c_42b3_8ec4_f7a1a48049e7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4b98e4c7_806a_4962_b9ce_195ac93ccae1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_41e466af_2759_4e05_b0e6_42c29ad1a773
boundary condition: true
is: SBO:0000252
initial amount: NaN
is encoded by: hsa:80025
has only substance units: false
initial concentration: NaN
name: PANK2
constant: true
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#cd13de6a_65c2_4447_acf3_542c7ebc93d0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6e3a38e2_71ed_40f2_83f1_51d427cb0aef
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9120e0a2_9a5c_46bb_ac65_a000bad0878b
value: 1000.0
type: LocalParameter

metaR IMACTD m
is described by: http://identifiers.org/pubmed/2071588
is version of: ECO:0000134
fast: false
type: Reaction
name: Imidazole acetaldeyde dehydrogenase (mito)
notes: GENE_ASSOCIATION: (219.1) or (8659.1) or (217.1) or (8659.2) SUBSYSTEM: Histidine metabolism EC Number: 1.5.1.12 Confidence Level: 2 AUTHORS: PMID:2071588 NOTES: SAB 2 H's on RHS are there to balance--not certain. enzymatic assay shows substrate used by aldehyde dehydrogenase in human liver
reversible: false
modifier: MODEL1109130000#
is: SBO:0000176
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.5.1.12
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_7f053044_f179_4ab5_8136_87131eb98fe5
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fd2f1560_ece9_461e_af47_64292009f27f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0305be45_946d_4d84_a5e7_21ec0922749f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_55067442_ccbf_4316_85d5_f747cc97e0bc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_77f5ef20_65f5_4542_9e8e_57d26492cc84
value: -1000.0
type: LocalParameter

metaR r0735
notes: GENE_ASSOCIATION: (AA081045.1) or (AI620219.1) or (219.1) or (217.1) or (224.1) or (501.1) or (223.1) or (AU149534.1) or (T83654.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.3.1.38 Confidence Level: 0 AUTHORS: PMID:12654921 NOTES:
reversible: true
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/12654921
reactant: MODEL1109130000#
is: SBO:0000176
modifier: MODEL1109130000#
fast: false
name: trans-Dec-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38
is version of: http://identifiers.org/ec-code/1.3.1.38

http://identifiers.org/biomodels.db/MODEL1109130000#e7fc8505_2f10_4641_bb3f_e0b83a3a2e25
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bd0b55ce_27ea_4ce3_abe4_d4d13cc0d46d
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC00001 e
notes: FORMULA: CHARGE: 0
is: SBO:0000247
boundary condition: false
initial concentration: 1.0
constant: false
initial amount: NaN
name: Albumin
has only substance units: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_ae795e82_2daa_45c6_b001_d7bc582a8d95
initial concentration: NaN
is: P35557
initial amount: NaN
is: SBO:0000252
type: Species
boundary condition: true
is encoded by: hsa:2645
name: GCK
constant: false
has only substance units: false

metaM glutcoa c
notes: FORMULA: C26H37N7O19P3S CHARGE: -5 INCHI: InChI=1S/C26H42N7O19P3S/c1-26(2,21(39)24(40)29-7-6-15(34)28-8-9-56-17(37)5-3-4-16(35)36)11-49-55(46,47)52-54(44,45)48-10-14-20(51-53(41,42)43)19(38)25(50-14)33-13-32-18-22(27)30-12-31-23(18)33/h12-14,19-21,25,38-39H,3-11H2,1-2H3,(H,28,34)(H,29,40)(H,35,36)(H,44,45)(H,46,47)(H2,27,30,31)(H2,41,42,43)/p-5/t14-,19-,20-,21+,25-/m1/s1
constant: false
is: SBO:0000247
has only substance units: false
initial amount: NaN
initial concentration: 1.0
type: Species
is: HMDB01339
name: glutaryl-CoA(5-)
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#b26a006c_0242_4e94_9ea7_3f665ff910f4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b9c1bc78_0f66_4991_96a8_cfd3120b7446
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_05658432_b53d_412c_92ea_d614953ce60a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b3b32738_9e80_47d7_ba4e_c4f9b7254a48
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_be51dd44_7a7e_49dd_9f7c_3a0f28274909
has part: P38606
is encoded by: hsa:245973
name: TCIRG1:ATP6V1C2:ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V0C:ATP6V1E1:ATP6V0B:ATP6V0E1:ATP6V0D1:ATP6V1F:ATP6V1G1
has part: Q8NEY4
initial concentration: NaN
is: SBO:0000297
is encoded by: hsa:529
has only substance units: false
has part: Q9Y5K8
has part: Q16864
is encoded by: hsa:526
is encoded by: hsa:9296
constant: false
is encoded by: hsa:523
has part: Q6IB33
is encoded by: hsa:51606
boundary condition: true
initial amount: NaN
type: Species
is encoded by: hsa:51382
has part: Q53Y06
has part: P21281
has part: B3KUZ7
is encoded by: hsa:9550

http://identifiers.org/biomodels.db/MODEL1109130000#_418fb61c_6742_40f1_9ba0_e0ccdbba1310
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cfd6cb73_fa08_4992_a68d_65f02c4b8865
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaM CE5121 c
constant: false
notes: FORMULA: C31H48N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5121
name: trans-3-decenoyl-CoA
boundary condition: false
initial amount: NaN
has only substance units: false
type: Species
initial concentration: 1.0
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_5be6a271_99b3_41e0_b27f_cf79914eb495
constant: true
initial concentration: NaN
initial amount: NaN
type: Species
name: CYP17A1
is: P05093
is: SBO:0000252
boundary condition: true
is encoded by: hsa:1586
has only substance units: false

metaM 4ppcys m
has only substance units: false
is: CHEBI:59458
boundary condition: false
notes: FORMULA: C12H20N2O9PS CHARGE: -3 INCHI: InChI=1S/C12H23N2O9PS/c1-12(2,6-23-24(20,21)22)9(16)10(17)13-4-3-8(15)14-7(5-25)11(18)19/h7,9,16,25H,3-6H2,1-2H3,(H,13,17)(H,14,15)(H,18,19)(H2,20,21,22)/p-3/t7-,9-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC01276 EHMN_ABBREVIATION: C04352
initial concentration: 1.0
is: HMDB01117
constant: false
initial amount: NaN
type: Species
is: SBO:0000247
name: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate(3-)

http://identifiers.org/biomodels.db/MODEL1109130000#_022aebb8_ac14_4a1f_a313_8cb4811d555b
units: dimensionless
value: 0.0
type: LocalParameter

metaR RTOTALCRNCPT1
is: SBO:0000176
type: Reaction
is version of: http://identifiers.org/ec-code/2.3.1.21
is described by: http://identifiers.org/pubmed/1988962
name: carnitine fatty-acyl transferase
modifier: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (1375.1) or (1375.4) or (1375.3) or (1374.1) or (126129.1) or (1375.2) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: PMID:1988962 NOTES: NJ
reversible: false
reactant: MODEL1109130000#
fast: false
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_74a38711_a229_48a7_bc71_3f250673f412
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_915a013d_b3f5_4836_b841_123efbde59b3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_45184606_c4a3_4e77_832e_b286cb1d5464
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE4855 r
initial amount: NaN
is: SBO:0000247
boundary condition: false
notes: FORMULA: C45H70N7O17P3S CHARGE: -4 INCHI: InChI=1/C45H74N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-36(54)73-29-28-47-35(53)26-27-48-43(57)40(56)45(2,3)31-66-72(63,64)69-71(61,62)65-30-34-39(68-70(58,59)60)38(55)44(67-34)52-33-51-37-41(46)49-32-50-42(37)52/h5-6,8-9,11-12,14-15,32-34,38-40,44,55-56H,4,7,10,13,16-31H2,1-3H3,(H,47,53)(H,48,57)(H,61,62)(H,63,64)(H2,46,49,50)(H2,58,59,60)/p-4/b6-5-,9-8-,12-11-,15-14-/t34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4855
type: Species
initial concentration: 1.0
constant: false
name: all-cis-12,15,18,21-tetracosatetraenoyl-CoA
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3dda2656_446d_430a_9b22_ca3a9a67d1b6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8482ecc_42c8_40ef_9eed_91ae5882f1c5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_06e0b8aa_f941_44e5_907e_bb9b85d851cc
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0abd137e_30ee_4584_8a4e_c3a81e3196bb
value: 1000.0
type: LocalParameter

metaR GLNALANaEx
reactant: MODEL1109130000#
is: SBO:0000185
product: MODEL1109130000#
is version of: ECO:0000269
type: Reaction
fast: false
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14530974
name: L-alanine/L-glutamine Na-dependent exchange (Gln-L in)
notes: GENE_ASSOCIATION: 6510.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:14530974 NOTES: SAB see Kanai and Hediger 2004 (2003), PMID 14530974
reversible: false

metaR RE3104R
name: RE3104
fast: false
type: Reaction
product: MODEL1109130000#
reversible: true
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 64834.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
is described by: http://identifiers.org/pubmed/10970790
reactant: MODEL1109130000#
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_1b55b54d_a120_49dd_8444_71091df9e1d9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0fd4b5be_4f4c_4be3_8862_f55e665ca8a3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_51dbe480_30d1_45e2_9c17_4096321db7b0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6ca21960_a6ac_47f9_be7c_dda9d718e2c6
is: Q13232
is: SBO:0000252
is encoded by: hsa:4832
has only substance units: false
initial amount: NaN
constant: false
name: NME3
initial concentration: NaN
boundary condition: true
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_39e60664_2c03_4f42_a960_ebf4ff3d4cb2
value: 0.0
type: LocalParameter

metaM ksii core2 deg4 l
has only substance units: false
boundary condition: false
name: keratan sulfate II (core 2-linked), degradation product 4
initial concentration: 1.0
type: Species
is: SBO:0000247
constant: false
initial amount: NaN
notes: FORMULA: C58H95N5O43SX CHARGE: -1 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#_366e4885_4ba7_4d0b_9b70_00345e6e4f5f
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE0713 x
notes: FORMULA: C39H60N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE0713
boundary condition: false
initial amount: NaN
has only substance units: false
name: 3-oxolinoleoyl-CoA
type: Species
constant: false
is: SBO:0000247
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#b9e6ae48_6f36_48ea_b5dd_54ae70aab6df
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_748c83c5_bd50_44d7_a313_64cd331bfb48
has only substance units: false
name: AK2
initial amount: NaN
initial concentration: NaN
type: Species
constant: false
boundary condition: true
is encoded by: hsa:204
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#ae20a043_f38c_47c7_89ce_443d925f1202
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_434b7dec_46d4_4ca0_bd7a_1d546722aafd
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_06d95f7e_b144_4f90_848e_1feaf664cccb
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5247c282_0d51_46b0_9cd4_038d465bfda2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_75e66e71_1548_4239_9a4a_74cc00ef9650
value: 1000.0
type: LocalParameter

metaR r0739
is described by: http://identifiers.org/pubmed/6338006
type: Reaction
modifier: MODEL1109130000#
product: MODEL1109130000#
fast: false
is version of: http://identifiers.org/ec-code/1.1.1.1
is: SBO:0000176
name: alcohol dehydrogenase Bile acid biosynthesis EC:1.1.1.1
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Bile acid synthesis EC Number: 1.1.1.1 Confidence Level: 0 AUTHORS: PMID:5487878,PMID:6338006,PMID:6379302 NOTES:
is described by: http://identifiers.org/pubmed/6379302
reversible: true
is described by: http://identifiers.org/pubmed/5487878
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_681e09ce_a668_433f_b30b_885ccf8b06cc
is: P30038
constant: true
type: Species
is: SBO:0000252
is encoded by: hsa:8659
name: ALDH4A1
boundary condition: true
initial concentration: NaN
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6383a604_ea06_4e93_a8be_de2365d66422
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c3661123_4e23_490b_8ce5_9977ec8bc925
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_56db5632_82d5_4673_8e2a_c97d550fea07
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

metaM CE1102 m
initial amount: NaN
boundary condition: false
has only substance units: false
type: Species
name: cis-(3S)-hydroxytetradec-7-enoyl-CoA
notes: FORMULA: C35H56N7O18P3S CHARGE: -4 INCHI: HEPATONET_1.0_ABBREVIATION: HC11102 EHMN_ABBREVIATION: CE1102
is: SBO:0000247
constant: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#c5529f56_de8e_4404_94a6_9c00f90b9d84
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_88aefe41_6a8f_4d27_be89_369e182e1041
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4bb7b143_8e77_4313_8ac4_ba40938b52ab
value: 0.0
type: LocalParameter

metaR RTOTALCRNCPT2
reversible: false
name: R group transport into the mitochondria
is version of: ECO:0000000
fast: false
is described by: http://identifiers.org/pubmed/1528846
is described by: http://identifiers.org/pubmed/1988962
is described by: http://identifiers.org/pubmed/11274214
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: PMID:11274214,PMID:1528846,PMID:1988962 NOTES: NJ
reactant: MODEL1109130000#
is: SBO:0000176
modifier: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_7a3cb6b7_e37d_4e48_9920_96c8b8d6d8c9
is: P36021
boundary condition: true
initial concentration: NaN
name: SLC16A2
initial amount: NaN
has only substance units: false
type: Species
constant: false
is encoded by: hsa:6567
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#a013a1f5_58ab_4255_9772_5967f49f32a0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e6e2f4d6_df6e_4ba2_9350_e1ced3a40c8c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a3f41ee7_7a79_4882_986f_31425f92d4c6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d34f7eb1_c9c0_4721_8da0_51bbcd1623df
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4ad4255d_b2cc_4308_9a59_c442bacd1e94
units: dimensionless
value: 0.0
type: LocalParameter

metaR C160CPT1
product: MODEL1109130000#
type: Reaction
modifier: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: (126129.1) or (1375.3) or (1374.1) or (1375.2) or (1375.1) or (1375.4) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: PMID:1988962 NOTES:
is: SBO:0000176
reversible: false
is version of: http://identifiers.org/ec-code/2.3.1.21
name: production of Palmitoylcarnitine
is version of: ECO:0000269
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1988962

http://identifiers.org/biomodels.db/MODEL1109130000#_0bb7b58c_ce20_42a9_893a_c5fd8a806ac8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24428770_6bc7_4b54_973e_4345e8265582
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c216fad7_4f6c_43ef_af60_af5cab0d8e5d
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_14f3e30e_43e2_4c2f_92f2_6e41355820a4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69fb9e17_7c7e_4e7d_88f8_643649e82a47
name: DNMT3A
initial concentration: NaN
boundary condition: true
has only substance units: false
type: Species
is encoded by: hsa:1788
constant: false
initial amount: NaN
is: SBO:0000252

metaM dag hs c
is: CHEBI:18035
initial amount: NaN
has only substance units: false
constant: false
notes: FORMULA: C3H6OFULLRCO2FULLR2CO2 CHARGE: 0 INCHI:
name: diglyceride
initial concentration: 1.0
type: Species
is: SBO:0000247
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_9a326443_3995_44a8_892d_5b8c07c7fbc2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_804c0f08_771e_4784_8943_6e765a7213b4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_fb07d36d_b064_475e_9e10_e614baadd2db
name: DGKG
type: Species
constant: false
is: SBO:0000252
boundary condition: true
has only substance units: false
is encoded by: hsa:1608
initial amount: NaN
is: P49619
notes: DRUGBANK_UNKNOWN: DB00144
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_018f4afa_4d50_49cf_a522_066629fe05eb
constant: true
is encoded by: hsa:54575
is: Q9HAW8
is: SBO:0000252
has only substance units: false
initial concentration: NaN
initial amount: NaN
boundary condition: true
type: Species
name: UGT1A10

http://identifiers.org/biomodels.db/MODEL1109130000#babcea82_67c0_4b6e_9a2b_be1da11a7842
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ea6550d3_663b_4916_a7a5_5ad22cd9fdb1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b43924e0_8e1c_4283_8834_8561a4e0aaf3
is encoded by: hsa:9107
boundary condition: true
initial concentration: NaN
is: Q9Y217
constant: false
name: MTMR6
has only substance units: false
is: SBO:0000252
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_2f9efe93_54f7_403d_b35b_e06936929784
units: dimensionless
value: 0.0
type: LocalParameter

metaR C160CPT2
is described by: http://identifiers.org/pubmed/1988962
fast: false
name: C160 transport into the mitochondria
is version of: http://identifiers.org/ec-code/2.3.1.21
is described by: http://identifiers.org/pubmed/1528846
is version of: ECO:0000269
reactant: MODEL1109130000#
type: Reaction
is: SBO:0000176
modifier: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: PMID:1528846,PMID:1988962 NOTES: TV
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_87ee78da_a9bb_4223_9ade_eaaa6ed4ff79
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_53cd3682_fc7a_480b_8d1b_defc8ca28341
value: 1000.0
type: LocalParameter

metaR EX 34hpp
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: Exchange of 3-(4-hydroxyphenyl)pyruvate
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_17f39d64_54b5_4bb9_81e9_88754bb607de
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3f187f6b_7e86_478d_80cf_4da904e6c802
value: 0.0
type: LocalParameter

metaR HESTRATRIOLte
is: SBO:0000185
reactant: MODEL1109130000#
reversible: true
is version of: ECO:0000000
type: Reaction
name: hydroxylated estrogen derivative transport
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 1 AUTHORS: NOTES: unknown mechanism, hydroxylated (inactivated) estrogen derivative needs to be exported NJ

metaM CE6182 m
name: 20-CoA-20-oxo-leukotriene B4
notes: FORMULA: C41H59N7O21P3S CHARGE: -5 INCHI: InChI=1/C41H64N7O21P3S/c1-41(2,24-66-72(63,64)69-71(61,62)65-23-29-35(68-70(58,59)60)34(55)40(67-29)48-26-47-33-37(42)45-25-46-38(33)48)36(56)39(57)44-20-19-30(51)43-21-22-73-32(54)18-11-5-3-4-8-13-27(49)14-9-6-7-10-15-28(50)16-12-17-31(52)53/h4,6-10,14-15,25-29,34-36,40,49-50,55-56H,3,5,11-13,16-24H2,1-2H3,(H,43,51)(H,44,57)(H,52,53)(H,61,62)(H,63,64)(H2,42,45,46)(H2,58,59,60)/p-5/b7-6+,8-4-,14-9+,15-10-/t27-,28-,29-,34+,35+,36u,40-/m0/s1 EHMN_ABBREVIATION: CE6182
initial concentration: 1.0
constant: false
type: Species
initial amount: NaN
has only substance units: false
boundary condition: false
is: SBO:0000247

metaR CORE7GTg
name: Core 7 alpha-GalNAc-transferase, Golgi apparatus
reactant: MODEL1109130000#
reversible: false
fast: false
is version of: ECO:0000000
is: SBO:0000176
type: Reaction
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: O-glycan synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: EC 2.4.1.- NCD

http://identifiers.org/biomodels.db/MODEL1109130000#_2b499d58_6e6c_41b4_88f5_0e9e9cf39b9a
name: MGST1
initial amount: NaN
has only substance units: false
initial concentration: NaN
type: Species
is encoded by: hsa:4257
boundary condition: true
is: SBO:0000252
is: P10620
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_8f86b4ed_93e1_471f_958b_c813eaff3d63
units: dimensionless
value: 0.0
type: LocalParameter

metaM l2xser g
boundary condition: false
initial amount: NaN
initial concentration: 1.0
is: http://identifiers.org/pubchem.substance/7386
constant: false
is: C04825
name: (Gal)2-Xyl-L-Ser (protein)
notes: FORMULA: C17H29O14X CHARGE: 0 EHMN_ABBREVIATION: C04825
type: Species
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_daa5b549_7310_48fa_8699_73870211406d
boundary condition: true
type: Species
constant: true
is: Q7LGA3
has only substance units: false
initial amount: NaN
is encoded by: hsa:9653
is: SBO:0000252
initial concentration: NaN
name: HS2ST1

http://identifiers.org/biomodels.db/MODEL1109130000#b6f66b33_a11c_4c43_8f5a_792e787721ec
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a21af519_0c98_415e_ad58_401ba63f1e75
has only substance units: false
is: A8K8F9
type: Species
boundary condition: true
is: SBO:0000252
name: PLCD1
initial amount: NaN
constant: true
initial concentration: NaN
is encoded by: hsa:5333

metaR TTDCAtr
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:10811962,PMID:11161786 NOTES:
fast: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11161786
name: tetradecanoate (transport)
reactant: MODEL1109130000#
is: SBO:0000185
reversible: true
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/10811962
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_7d0b8daa_3675_4e26_9f34_d11ab0ae2e4b
type: Species
has only substance units: false
is: P21397
is encoded by: hsa:4128
is: SBO:0000252
name: MAOA
boundary condition: true
initial amount: NaN
initial concentration: NaN
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#d214f371_5381_43ad_88d1_d697a4318d4f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_05cc758f_7f62_4d3c_b832_12952522cdf4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_329713af_9464_4c4f_9133_d76e8313077a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_22f5f97b_5a91_47f2_b3e0_5f1cb6f1d1c3
name: _100128062_1_m
is encoded by: hsa:100128062
initial amount: NaN
has only substance units: false
constant: false
boundary condition: true
type: Species
initial concentration: NaN
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_524c387b_1a13_4f73_b14e_c90e2657e45d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_132d2102_a11d_4a5d_b73a_aead36532ea7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e6be6dbb_4bd7_460e_a336_5fb15fa5a130
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3d739bd7_abf0_41fb_8115_2adcc0191793
has only substance units: false
initial amount: NaN
boundary condition: true
is encoded by: hsa:83549
constant: false
name: UCK1
initial concentration: NaN
type: Species
is: Q5JT09
is: SBO:0000252

metaR OIVD3m
modifier: MODEL1109130000#
reactant: MODEL1109130000#
reversible: false
is version of: ECO:0000269
name: 2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxopentanoate), mitochondrial
is version of: http://identifiers.org/ec-code/1.8.1.4
is described by: http://identifiers.org/pubmed/1429740
type: Reaction
notes: GENE_ASSOCIATION: (1629.1) and (594.1 and 593.1) and (1738.1) or (1629.1) and (1738.1) and (594.2 and 593.1) SUBSYSTEM: Valine, leucine, and isoleucine metabolism EC Number: 1.8.1.4 Confidence Level: 4 AUTHORS: PMID:1429740,PMID:2914958 NOTES:
is described by: http://identifiers.org/pubmed/2914958
product: MODEL1109130000#
is: SBO:0000176
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_5c3f8ba6_5790_48b1_89b8_43b983781031
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9646c942_6e06_4b98_8804_0e1e5a69b1f6
value: 0.0
type: LocalParameter

metaR TXASr
type: Reaction
is version of: ECO:0000134
is version of: http://identifiers.org/ec-code/5.3.99.5
name: Thromboxane-A synthase
reversible: false
notes: GENE_ASSOCIATION: 6916.1 SUBSYSTEM: Eicosanoid metabolism EC Number: 5.3.99.5 Confidence Level: 0 AUTHORS: PMID:10903770,PMID:2491846,PMID:7811713 NOTES: NJ
is: SBO:0000176
is described by: http://identifiers.org/pubmed/2491846
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10903770
fast: false
is described by: http://identifiers.org/pubmed/7811713
product: MODEL1109130000#
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_8d4b4808_5817_4040_89b8_fe7a5924d8ee
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_518890ab_d7a9_4859_92b6_e554ede500eb
value: 1000.0
type: LocalParameter

metaR EX ura LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Uracil exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_14093753_533d_46aa_b509_aaf71c4d6304
is: B2RCP4
is: SBO:0000252
is encoded by: hsa:51447
has only substance units: false
name: IP6K2
initial amount: NaN
type: Species
initial concentration: NaN
boundary condition: true
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_1ddd7c8e_f7ef_4fc6_bcee_e40100ab906b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a5afe7d_c0da_4620_9c9a_9424178c6b8c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0bb18915_2ca6_4a50_a9e3_1ce00c86b43d
value: 0.0
type: LocalParameter

metaR ASPTA
is described by: http://identifiers.org/pubmed/2225456
notes: GENE_ASSOCIATION: 2805.1 SUBSYSTEM: Alanine and aspartate metabolism EC Number: 2.6.1.1 Confidence Level: 4 AUTHORS: PMID:2225456,PMID:6930651 NOTES:
fast: false
reversible: true
is version of: ECO:0000269
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/6930651
is version of: http://identifiers.org/ec-code/2.6.1.1
type: Reaction
product: MODEL1109130000#
name: aspartate transaminase
modifier: MODEL1109130000#

metaR RE3220C
is: SBO:0000176
is described by: http://identifiers.org/pubmed/2969800
name: RE3220
is version of: http://identifiers.org/ec-code/3.1.6.2
type: Reaction
modifier: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 412.1 SUBSYSTEM: Androgen and estrogen synthesis and metabolism EC Number: 3.1.6.2 Confidence Level: 0 AUTHORS: PMID:2969800 NOTES: IT - fixed proton
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_62e79a6a_5382_4e32_954b_3a65b8b07de4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b7e2ded_321d_4ffd_aa48_03770a1c80ff
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2ff915cb_ffc4_4e26_99b2_4d72fc056fc8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#edb9cf33_cb9e_4dcc_96a7_d4c2092123ca
units: dimensionless
value: 0.0
type: LocalParameter

metaM crtsl c
constant: false
is: SBO:0000247
is: HMDB00063
is: CHEBI:17650
name: cortisol
notes: FORMULA: C21H30O5 CHARGE: 0 INCHI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 EHMN_ABBREVIATION: C00735
initial concentration: 1.0
boundary condition: false
has only substance units: false
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_82f29feb_2781_494c_9764_19dcd15347ab
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_70c6c11d_f6fe_40ce_8c27_5dbde746164b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8c73fe58_282a_4d2c_900c_4328bbbd9e35
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7a83ebc9_e056_4342_9c01_14dfa979351c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_10c4fc31_7fc7_4cbc_aa92_7c11e7b4b40c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b7e0a35c_1b12_44e1_af6a_6355a8e58d81
value: 1000.0
type: LocalParameter

metaR S6TASE11ly
is described by: http://identifiers.org/pubmed/3196333
is version of: http://identifiers.org/ec-code/3.1.6.14
reversible: true
name: N-acetylglucosamine-6-sulfatase, lysosomal
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/3689315
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3689314
fast: false
is: SBO:0000176
is version of: ECO:0000000
notes: GENE_ASSOCIATION: 2799.1 SUBSYSTEM: Keratan sulfate degradation EC Number: 3.1.6.14 Confidence Level: 4 AUTHORS: PMID:3196333,PMID:3689314,PMID:3689315 NOTES: NCD

http://identifiers.org/biomodels.db/MODEL1109130000#_fdecfb83_5cbf_4cc3_85d6_e8268dd61979
is encoded by: hsa:1384
constant: true
boundary condition: true
is: SBO:0000252
name: CRAT
type: Species
initial concentration: NaN
initial amount: NaN
has only substance units: false

metaM dag hs e
type: Species
is: CHEBI:18035
is: SBO:0000247
constant: false
boundary condition: false
initial amount: NaN
notes: FORMULA: C3H6OFULLRCO2FULLR2CO2 CHARGE: 0 INCHI:
has only substance units: false
name: diglyceride
initial concentration: 1.0

metaR FORtrn
type: Reaction
product: MODEL1109130000#
is version of: ECO:0000000
name: Formate transport, nuclear
reversible: true
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, nuclear EC Number: Confidence Level: 2 AUTHORS: NOTES: IT
fast: false
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_59e170e3_2961_4344_8480_11fd3e78a9e4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1f0fa0e9_334b_4f5f_9644_b3728e537490
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_2b831594_7037_4521_9dd6_f02ab8b36fba
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24e6df52_017c_4756_af95_5c8351e03cf8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_92493822_330c_409a_a067_413555167b25
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_99463658_37ba_4e6b_a46d_36d694cf8416
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d937bc7d_69f0_473e_a45d_1b91250dedcf
units: dimensionless
value: 0.0
type: LocalParameter

metaM crtsl e
boundary condition: false
constant: false
type: Species
has only substance units: false
is: SBO:0000247
is: HMDB00063
name: cortisol
is: CHEBI:17650
initial amount: NaN
notes: FORMULA: C21H30O5 CHARGE: 0 INCHI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 EHMN_ABBREVIATION: C00735
initial concentration: 1.0

metaR NACHEX18ly
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) or (3074.1) SUBSYSTEM: Keratan sulfate degradation EC Number: 3.2.1.52 Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: NCD
fast: false
is: SBO:0000176
is described by: http://identifiers.org/pubmed/12706724
is version of: http://identifiers.org/ec-code/3.2.1.52
is version of: ECO:0000000
type: Reaction
name: beta-N-acetylhexosaminidase, lysosomal
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10336991
reversible: false
is described by: http://identifiers.org/pubmed/8993162
is described by: http://identifiers.org/pubmed/11707436
reactant: MODEL1109130000#

metaM xoltri25 r
boundary condition: false
name: 7alpha,25-dihydroxycholesterol
initial amount: NaN
constant: false
is: SBO:0000247
initial concentration: 1.0
is: HMDB06280
is: CHEBI:37623
has only substance units: false
notes: FORMULA: C27H46O3 CHARGE: 0 INCHI: InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23-,24+,26+,27-/m1/s1
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_0617baf1_ae68_4df5_94d1_bc3c733efc59
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_925adef0_f048_4376_8977_0f8b011adf48
constant: false
is encoded by: hsa:80168
type: Species
initial concentration: NaN
boundary condition: true
is: Q3SYC2
name: MOGAT2
initial amount: NaN
is: SBO:0000252
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#cddd3f5d_0282_43c9_b5a2_a42ca75d53c9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3f750ea2_d47e_4837_8e91_5b2b464e0708
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a353104b_8d06_44df_a8b6_b1fc4b62896e
value: 0.0
type: LocalParameter

metaM CE6182 c
initial concentration: 1.0
notes: FORMULA: C41H59N7O21P3S CHARGE: -5 INCHI: InChI=1/C41H64N7O21P3S/c1-41(2,24-66-72(63,64)69-71(61,62)65-23-29-35(68-70(58,59)60)34(55)40(67-29)48-26-47-33-37(42)45-25-46-38(33)48)36(56)39(57)44-20-19-30(51)43-21-22-73-32(54)18-11-5-3-4-8-13-27(49)14-9-6-7-10-15-28(50)16-12-17-31(52)53/h4,6-10,14-15,25-29,34-36,40,49-50,55-56H,3,5,11-13,16-24H2,1-2H3,(H,43,51)(H,44,57)(H,52,53)(H,61,62)(H,63,64)(H2,42,45,46)(H2,58,59,60)/p-5/b7-6+,8-4-,14-9+,15-10-/t27-,28-,29-,34+,35+,36u,40-/m0/s1 EHMN_ABBREVIATION: CE6182
name: 20-CoA-20-oxo-leukotriene B4
initial amount: NaN
type: Species
boundary condition: false
has only substance units: false
is: SBO:0000247
constant: false

metaM CE2020 m
type: Species
is: CHEBI:59002
is: SBO:0000247
constant: false
initial concentration: 1.0
initial amount: NaN
name: N-arachidonoylglycinate
boundary condition: false
notes: FORMULA: C22H34NO3 CHARGE: -1 INCHI: InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/p-1/b7-6-,10-9-,13-12-,16-15- EHMN_ABBREVIATION: CE2020
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_9001f5fd_172e_4050_bde2_f2966d64f67c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6f00301a_0e72_4866_b410_e09a58771438
value: 1000.0
type: LocalParameter

metaR S6TASE24ly
notes: GENE_ASSOCIATION: 2799.1 SUBSYSTEM: Keratan sulfate degradation EC Number: 3.1.6.14 Confidence Level: 4 AUTHORS: PMID:3196333,PMID:3689314,PMID:3689315 NOTES: NCD
is version of: http://identifiers.org/ec-code/3.1.6.14
is described by: http://identifiers.org/pubmed/3689315
type: Reaction
reactant: MODEL1109130000#
is version of: ECO:0000000
fast: false
name: N-acetylglucosamine-6-sulfatase, lysosomal
reversible: true
is: SBO:0000176
is described by: http://identifiers.org/pubmed/3196333
product: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3689314

http://identifiers.org/biomodels.db/MODEL1109130000#_482c6d5e_2078_45c7_9599_1e1e29edff12
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_44c3e270_5b3f_4abe_b039_9b526e57cc12
value: 1000.0
type: LocalParameter

metaR RE3552X
type: Reaction
name: RE3552
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: 1.2.1.3 Confidence Level: 0 AUTHORS: PMID:12054595 NOTES:
product: MODEL1109130000#
fast: false
is version of: http://identifiers.org/ec-code/1.2.1.3
reversible: true
is described by: http://identifiers.org/pubmed/12054595
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#a9eae52d_1c97_4588_8d0e_d14880e669d2
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3c048f0e_8e44_4f2a_904a_d5b2435990fe
has only substance units: false
type: Species
is encoded by: hsa:25841
initial concentration: NaN
is: SBO:0000252
initial amount: NaN
name: ABTB2
boundary condition: true
is: Q8N961
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#e0cbb5e0_136e_4175_847d_2dcf3ab367ae
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a94c7217_336a_40aa_bc4b_f5a6e0408cde
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_969e31dc_4655_4bac_a697_38b12bcce44e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_589bc7cf_a8ce_47f5_9dbb_aaba9f6ffd22
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31f454d1_ed22_43e4_a9e7_504489625857
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_968ae948_c4f3_4210_838a_eacd9e6d325d
value: 0.0
type: LocalParameter

metaM CE6448 c
is: SBO:0000247
name: 14-hydroperoxy-H4-neuroprostane
type: Species
notes: FORMULA: C22H31O6 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE6448
constant: false
initial concentration: 1.0
has only substance units: false
boundary condition: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_93f5d47b_8424_4c37_80aa_cb65fe39c0e3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4f197a74_86f6_40e3_bdbf_c53e7d23fffe
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0d53e70e_146d_4bc1_84bd_39fdbf3c2d2b
initial concentration: NaN
is encoded by: hsa:84444
boundary condition: true
type: Species
is: SBO:0000252
name: DOT1L
has only substance units: false
constant: false
initial amount: NaN
is: Q8TEK3

http://identifiers.org/biomodels.db/MODEL1109130000#fc227eba_6f9b_4440_a69d_755b042fb1ac
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d65b494f_4105_49b7_809c_575c33ea30c6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_41098e7e_506b_4ef9_9a11_835d50a94dd5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5510f192_3cfe_4d56_80c0_d46c905e2ce0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f99e80ec_b22b_4f0c_be99_4b43bc4815b7
value: 0.0
type: LocalParameter

metaR CYSALANaEx
is: SBO:0000185
reversible: false
fast: false
is version of: ECO:0000269
modifier: MODEL1109130000#
product: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: (6509.1) or (6510.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:14530974 NOTES: SAB see Kanai and Hediger 2004 (2003), PMID 14530974
is described by: http://identifiers.org/pubmed/14530974
name: L-alanine/L-cysteine Na-dependent exchange (Cys-L in)
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_1f674e97_d058_4a96_8d8f_291d4a649ff1
name: DGKQ
is: SBO:0000252
initial amount: NaN
constant: true
type: Species
initial concentration: NaN
has only substance units: false
boundary condition: true
is encoded by: hsa:1609
is: Q59FF7

http://identifiers.org/biomodels.db/MODEL1109130000#_589ba25d_292c_473c_a598_f6ceab0b6c59
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_153c379a_3dd7_42d3_8be1_9ddbcdf4f0e3
is encoded by: hsa:AD000092
name: _AD000092_1_c
constant: false
initial concentration: NaN
boundary condition: true
has only substance units: false
initial amount: NaN
is: SBO:0000252
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_44ae77ba_c889_4341_846e_a258e5c9dac0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bbe975db_6caa_404d_b480_0b91f427e992
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_330a60d6_f881_4832_a8f8_7b256e9591b9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5eb2504a_b073_44a5_83ce_6d0095d9a489
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b528158_2185_414c_aa13_e779739173d4
value: 0.0
type: LocalParameter

metaR EX bglc LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: Exchange reaction for beta glucans
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_925e91cb_c633_4284_9574_5dca60c3600f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_861f53e2_9b77_405d_a852_5c598c441e58
type: Species
has only substance units: false
constant: true
is: SBO:0000252
name: CYP39A1
initial concentration: NaN
boundary condition: true
initial amount: NaN
is: Q9NYL5
is encoded by: hsa:51302

http://identifiers.org/biomodels.db/MODEL1109130000#_0a3e650b_b541_4422_a06e_cd160dd26313
type: Species
is: Q9UBM7
is: SBO:0000252
has only substance units: false
constant: false
initial concentration: NaN
is encoded by: hsa:1717
boundary condition: true
initial amount: NaN
name: DHCR7

http://identifiers.org/biomodels.db/MODEL1109130000#_0a721b4a_0f69_4e6f_9dc9_3e380d07d397
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a907dec3_624e_4008_86de_b3469ba3a080
initial concentration: NaN
is encoded by: hsa:2224
name: FDPS
is: SBO:0000252
boundary condition: true
type: Species
initial amount: NaN
has only substance units: false
is: E9PCI9
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#afd10bd3_3c2f_4599_9860_50d369431ea3
value: 0.0
type: LocalParameter

metaR GLCt4
reversible: true
fast: false
modifier: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction
is: SBO:0000185
is described by: http://identifiers.org/pubmed/1372904
notes: GENE_ASSOCIATION: (200010.1) or (159963.1) or (6526.1) or (125206.1) or (6524.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:11133510,PMID:12436245,PMID:12748858,PMID:1372904,PMID:1415574,PMID:15546855,PMID:7537337,PMID:7789985,PMID:8282810 NOTES: NCD
is described by: http://identifiers.org/pubmed/11133510
is described by: http://identifiers.org/pubmed/12748858
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7537337
is described by: http://identifiers.org/pubmed/1415574
name: glucose transport via sodium symport
is described by: http://identifiers.org/pubmed/8282810
is described by: http://identifiers.org/pubmed/15546855
is described by: http://identifiers.org/pubmed/12436245
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/7789985

metaM CE5121 m
name: trans-3-decenoyl-CoA
is: SBO:0000247
initial amount: NaN
constant: false
has only substance units: false
initial concentration: 1.0
notes: FORMULA: C31H48N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5121
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#a8f2666d_202f_44fb_a98a_bcde1ae52b24
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7bbebe5a_993b_492d_8ef2_5358719caf47
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b5b03bc8_ec2e_4e62_a336_3286eb2f7e26
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f32cdeb8_31cd_450f_940a_27c375de4856
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4a5aa78c_6757_43ed_83e1_b41fbccab50b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ffe72a57_6fa3_4cc5_8385_966334ab5cd3
value: 1000.0
type: LocalParameter

metaR PROD2m
is described by: http://identifiers.org/pubmed/10192398
name: Proline dehydrogenase (m)
reversible: false
is version of: http://identifiers.org/ec-code/1.5.99.8
is version of: ECO:0000254
fast: false
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 5625.1 SUBSYSTEM: Arginine and Proline Metabolism EC Number: 1.5.99.8 Confidence Level: 2 AUTHORS: PMID:10192398 NOTES: JLR SAB m
modifier: MODEL1109130000#
type: Reaction
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#ef4ad7c9_1b11_481d_b0c9_e6318e5b310a
value: -1000.0
type: LocalParameter

metaR EX HC02217 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: prostaglandin-g2 exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_ff8c0f5b_06af_4e2b_848b_87c5c901c432
initial amount: NaN
is: SBO:0000252
is: O00767
boundary condition: true
initial concentration: NaN
constant: false
has only substance units: false
is encoded by: hsa:6319
type: Species
name: SCD

http://identifiers.org/biomodels.db/MODEL1109130000#_957203c2_c63d_4f48_a68a_af116b4cb126
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_555ef25e_a927_427d_8234_e6a5dec15daa
constant: true
initial concentration: NaN
has part: Q7Z5W8
is encoded by: hsa:31
notes: DRUGBANK_UNKNOWN: DB00121, DB00173, DB02859, DB03781, DB07870
has part: O00763
boundary condition: true
type: Species
is encoded by: hsa:32
is: SBO:0000297
name: ACACA:ACACB
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_68cf1ed2_4086_469f_b9e1_84fee6fac31a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_04e1fdda_0deb_41e5_a504_2ba09099e5b6
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_e9fa4ba9_7426_4118_ab6d_9bcb0c0dd262
has only substance units: false
constant: true
is: SBO:0000252
boundary condition: true
is: Q969S0
initial amount: NaN
type: Species
is encoded by: hsa:84912
name: SLC35B4
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#ebcca4cc_14b5_4f05_8d60_d77cb1152162
units: dimensionless
value: 0.0
type: LocalParameter

metaM dag hs n
boundary condition: false
initial amount: NaN
constant: false
notes: FORMULA: C3H6OFULLRCO2FULLR2CO2 CHARGE: 0 HEPATONET_1.0_ABBREVIATION: HC02055 INCHI:
initial concentration: 1.0
name: diglyceride
is: CHEBI:18035
has only substance units: false
is: SBO:0000247
type: Species

metaR RE3104C
type: Reaction
reversible: true
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10970790
name: RE3104
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
reactant: MODEL1109130000#
is: SBO:0000176

metaM nmn m
boundary condition: false
is: HMDB00229
initial concentration: 1.0
is: SBO:0000247
is: CHEBI:14649
notes: FORMULA: C11H14N2O8P CHARGE: -1 INCHI: InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/p-1/t7-,8-,9-,11-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00366 EHMN_ABBREVIATION: C00455
has only substance units: false
type: Species
constant: false
initial amount: NaN
name: NMN(-)

http://identifiers.org/biomodels.db/MODEL1109130000#_7eae151f_df4f_4032_b44b_23a7b2acd700
constant: false
has only substance units: false
is encoded by: hsa:4707
is: SBO:0000252
initial amount: NaN
is: O75438
name: NDUFB1
initial concentration: NaN
boundary condition: true
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#b389d319_2bd4_46d1_b5b9_5511176e6a1e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_99af9ee4_e5d1_4985_ae92_c9edc21803b5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_701f2c47_cc37_4e44_aba2_032c76f3d17f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_34f5ae74_9b49_4575_8408_0a0dc200974f
units: dimensionless
value: 0.0
type: LocalParameter

metaM nmn n
type: Species
constant: false
initial amount: NaN
has only substance units: false
initial concentration: 1.0
is: HMDB00229
name: NMN(-)
is: SBO:0000247
notes: FORMULA: C11H14N2O8P CHARGE: -1 INCHI: InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/p-1/t7-,8-,9-,11-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00366 EHMN_ABBREVIATION: C00455
is: CHEBI:14649
boundary condition: false

metaR EX hdcea LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for Hexadecenoate (n-C16:1)
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_4527a05d_bc89_4663_ac07_6f493514c5e4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cd8cc07f_b190_40d3_8403_6431615ebcc2
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_944c4d5d_7572_476f_8d97_9638cb2238a5
value: -1000.0
type: LocalParameter

metaR r0767
reversible: true
fast: false
is: SBO:0000176
name: Decanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
is version of: http://identifiers.org/ec-code/2.3.1.85
type: Reaction
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (1962.1) or (3033.1) or (3030.1) or (3028.1) or (3295.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
reactant: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7567999

http://identifiers.org/biomodels.db/MODEL1109130000#_48018290_cdfd_4267_a4de_e143350dc502
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ad5795da_e89c_4f7b_b9ef_5502b56ce0a5
value: 0.0
type: LocalParameter

metaM HC02200 c
is: SBO:0000247
boundary condition: false
has only substance units: false
initial concentration: 1.0
initial amount: NaN
type: Species
name: S-glutathionyl-2-4-dinitrobenzene
constant: false
notes: FORMULA: CHARGE: 0 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#de6a7076_a272_4c23_ac96_59d3e6e7edf6
value: 1000.0
type: LocalParameter

metaR EX CE4724 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: apelin (1-12) exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#ce7be013_831d_4680_98a3_26f77005b863
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33e741a1_b94a_44ce_8f71_3c2f18b49f1c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7615b6ba_c013_44cb_a64c_c37d814ed4ba
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e7aac729_25ca_4934_aa2e_91b96f09fc19
units: dimensionless
value: 0.0
type: LocalParameter

metaR OAADC
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Unassigned Confidence Level: 4 AUTHORS: EC Number: NOTES: GENE_ASSOCIATION:
is: SBO:0000176
fast: false
reversible: false
name: oxaloacetate decarboxylase
type: Reaction

metaR r0768
name: Decanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false
notes: GENE_ASSOCIATION: (1962.1) or (3033.1) or (3030.1) or (3028.1) or (3295.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7567999
is described by: http://identifiers.org/pubmed/7834997
type: Reaction
is described by: http://identifiers.org/pubmed/11750882
is described by: http://identifiers.org/pubmed/6137188
is described by: http://identifiers.org/pubmed/8962082
is described by: http://identifiers.org/pubmed/4452359
reversible: true
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_95cbf00a_eda0_4551_bf29_04561818abf2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9d0de0c1_0a72_4b9b_873a_f7443fa52210
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_258ef671_7b9b_460c_bc94_64bde2398f94
value: 0.0
type: LocalParameter

metaR XYLTt
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 1 AUTHORS: PMID:6821187 NOTES: NCD
name: Xylitol transport via passive diffusion
reactant: MODEL1109130000#
reversible: true
fast: false
is: SBO:0000185
is described by: http://identifiers.org/pubmed/6821187
product: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#a0b76995_45e8_4643_a4f8_1f81d66faf8a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4cd982a1_3344_4952_bf9c_80a6b732761b
units: dimensionless
value: 0.0
type: LocalParameter

metaR NMNS
type: Reaction
reversible: false
fast: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: NAD metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:19513556 NOTES:
name: NMN synthetase
product: MODEL1109130000#
is version of: ECO:0000134
is: SBO:0000176
is described by: http://identifiers.org/pubmed/19513556

metaR RE3550X
reversible: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12054595
is version of: http://identifiers.org/ec-code/1.14.13.34
fast: false
type: Reaction
is: SBO:0000176
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: 1.14.13.34 Confidence Level: 0 AUTHORS: PMID:12054595 NOTES:
name: RE3550

metaR r0769
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7567999
type: Reaction
is described by: http://identifiers.org/pubmed/11750882
is described by: http://identifiers.org/pubmed/4452359
notes: GENE_ASSOCIATION: (1892.1) or (1962.1) or (3030.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
is described by: http://identifiers.org/pubmed/8962082
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7834997
is described by: http://identifiers.org/pubmed/6137188
name: (3R)-3-Hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
reversible: true
reactant: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_457991b5_8d0f_449d_8ce8_9aee429016ea
value: 0.0
type: LocalParameter

metaM HC02200 e
initial amount: NaN
initial concentration: 1.0
boundary condition: false
has only substance units: false
type: Species
constant: false
name: S-glutathionyl-2-4-dinitrobenzene
is: SBO:0000247
notes: FORMULA: CHARGE: 0 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#_2c6c46d1_209a_413a_b2cd_8ab869e18c57
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b5ce7b11_b30f_4dc7_9b70_66fb5b70195b
is encoded by: hsa:593
is: SBO:0000252
constant: true
initial concentration: NaN
is: P12694
type: Species
initial amount: NaN
has only substance units: false
boundary condition: true
name: BCKDHA

http://identifiers.org/biomodels.db/MODEL1109130000#_1ee0f9e4_0ba0_4fa8_a2d5_278e648cb5aa
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_312be0f6_ed08_4929_a27a_0da10f077748
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f642afd_7a2e_4720_99e6_0c352be13dfd
constant: true
type: Species
is encoded by: hsa:51447
boundary condition: true
has only substance units: false
initial concentration: NaN
name: IP6K2
is: SBO:0000252
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_8f8153c9_7fea_498f_bb53_0839a7056529
is: F5H066
initial concentration: NaN
boundary condition: true
name: SLC12A4
is: SBO:0000252
is encoded by: hsa:6560
constant: false
type: Species
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_90c831d8_1eca_4e80_b236_cdb9927e0b3e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a4f1f47a_ac0e_466f_bddc_509c2e88b0e6
units: dimensionless
value: 0.0
type: LocalParameter

metaR XYLUR
is described by: http://identifiers.org/pubmed/11882650
notes: GENE_ASSOCIATION: 51181.1 SUBSYSTEM: Pentose phosphate pathway EC Number: 1.1.1.10 Confidence Level: 4 AUTHORS: PMID:11882650,PMID:6821187 NOTES:
reactant: MODEL1109130000#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.1.1.10
product: MODEL1109130000#
fast: false
name: xylulose reductase
is described by: http://identifiers.org/pubmed/6821187
reversible: true
is version of: ECO:0000269
type: Reaction
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_15d381f9_fcd8_4a90_98e9_815e6017fd1e
value: 1000.0
type: LocalParameter

metaR DALAxt
fast: false
product: MODEL1109130000#
reversible: false
is: SBO:0000185
type: Reaction
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: D-alanine metabolism EC Number: Confidence Level: 1 AUTHORS: NOTES: SAB
name: D-Alanine transport to perixosome
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#fd97ab38_361a_413e_b3f0_a31188c9297b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a1d8e834_6681_4453_91a1_699855c7854b
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE6182 x
constant: false
initial concentration: 1.0
is: SBO:0000247
name: 20-CoA-20-oxo-leukotriene B4
type: Species
initial amount: NaN
boundary condition: false
notes: FORMULA: C41H59N7O21P3S CHARGE: -5 INCHI: InChI=1/C41H64N7O21P3S/c1-41(2,24-66-72(63,64)69-71(61,62)65-23-29-35(68-70(58,59)60)34(55)40(67-29)48-26-47-33-37(42)45-25-46-38(33)48)36(56)39(57)44-20-19-30(51)43-21-22-73-32(54)18-11-5-3-4-8-13-27(49)14-9-6-7-10-15-28(50)16-12-17-31(52)53/h4,6-10,14-15,25-29,34-36,40,49-50,55-56H,3,5,11-13,16-24H2,1-2H3,(H,43,51)(H,44,57)(H,52,53)(H,61,62)(H,63,64)(H2,42,45,46)(H2,58,59,60)/p-5/b7-6+,8-4-,14-9+,15-10-/t27-,28-,29-,34+,35+,36u,40-/m0/s1 EHMN_ABBREVIATION: CE6182
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_2fb268c8_9fff_461e_b6c3_a714364c649c
value: -1000.0
type: LocalParameter

metaR EX 5dhf LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: pentaglutamyl folate (DHF) exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_8312d799_2026_4e81_9d89_33898204adc9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6329990d_f030_4a2b_9723_ea547bda6b9d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_383d93a4_c22a_4a9c_aa43_bce395456fda
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24d81ca6_0046_4125_bd7a_ad524a4db680
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_398d86e9_95fc_443c_bc33_55b631e4706a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_23f65cb7_9b3f_40bd_b252_e43293a7e22e
value: 0.0
type: LocalParameter

metaR r0763
reactant: MODEL1109130000#
is: SBO:0000176
reversible: true
type: Reaction
fast: false
product: MODEL1109130000#
name: Hexanoyl-[acyl-carrier protein]:oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
is described by: http://identifiers.org/pubmed/7567999
is version of: http://identifiers.org/ec-code/2.3.1.85
notes: GENE_ASSOCIATION: (1962.1) or (3033.1) or (3030.1) or (3028.1) or (3295.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_20433d1e_084b_489d_ab77_f3a6ac821706
value: -1000.0
type: LocalParameter

metaM h2 c
type: Species
boundary condition: false
name: Hydrogen
is: SBO:0000247
is: CHEBI:18276
has only substance units: false
constant: false
notes: FORMULA: H2 CHARGE: 0 INCHI: InChI=1S/H2/h1H EHMN_ABBREVIATION: C00282
is: HMDB01362
initial concentration: 1.0
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_81042278_4a81_4433_a592_aba7abee07e6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8f9b89cc_0a8a_49ef_9b84_eb72b91686ee
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74571e1f_8ca8_4381_a730_34bb1ec06932
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_15ea93f5_2b84_41c7_a28c_55bf230e76bb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fd5ce5a7_5879_4645_95cc_e1506a3fe06b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_051eca3b_ba52_4520_aa95_75e787c08a79
value: 0.0
type: LocalParameter

metaM dag hs r
is: SBO:0000247
is: CHEBI:18035
name: diglyceride
boundary condition: false
initial concentration: 1.0
initial amount: NaN
has only substance units: false
type: Species
constant: false
notes: FORMULA: C3H6OFULLRCO2FULLR2CO2 CHARGE: 0 HEPATONET_1.0_ABBREVIATION: HC02055 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#e16c69b5_606d_49ed_b2d9_2b697de153d8
value: 0.0
type: LocalParameter

metaR r0764
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/6137188
reversible: true
name: hexanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
is described by: http://identifiers.org/pubmed/7567999
is described by: http://identifiers.org/pubmed/11750882
is: SBO:0000176
is described by: http://identifiers.org/pubmed/4452359
is described by: http://identifiers.org/pubmed/7834997
type: Reaction
notes: GENE_ASSOCIATION: (1962.1) or (3033.1) or (3030.1) or (3028.1) or (3295.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
is described by: http://identifiers.org/pubmed/8962082
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false
reactant: MODEL1109130000#
modifier: MODEL1109130000#

metaM crtsl r
constant: false
is: HMDB00063
is: CHEBI:17650
notes: FORMULA: C21H30O5 CHARGE: 0 INCHI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 EHMN_ABBREVIATION: C00735
initial amount: NaN
type: Species
is: SBO:0000247
name: cortisol
initial concentration: 1.0
has only substance units: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_1aa8c070_7659_4710_bb11_e8cefa674bd3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3db3126c_6d3c_4fdc_9672_e41fad9215c4
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_54e74a3c_4efe_491d_a513_f7dc6c79c1a8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_45160acf_5d38_47e7_82ff_d001cd0a958d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#db1c21fa_1bd6_42c3_a65f_45eb0e2bf75a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_50b78a4f_3e14_473f_996d_84095c296bf1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8c23391_f076_402e_bc3e_a4c640e76286
value: 0.0
type: LocalParameter

metaR NACUP
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES: JLR
is version of: ECO:0000000
is: SBO:0000185
name: Nicotinic acid uptake
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_9b2e08ca_388a_4953_9832_9fcae114568c
type: Species
has only substance units: false
is: Q7KZA3
initial concentration: NaN
initial amount: NaN
name: FECH
constant: true
is encoded by: hsa:2235
boundary condition: true
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#b6a2c9db_ddf2_4b97_ac5b_08f7b34b8bed
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_162fcc90_4728_42c1_84be_e1c54c30473f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_32dbf35d_7fc4_4615_a091_97c7d3c4ced8
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_daab0f5f_3335_4ed0_bafb_27f9378605cf
initial concentration: NaN
constant: true
has only substance units: false
boundary condition: true
initial amount: NaN
is: P13995
is encoded by: hsa:10797
name: MTHFD2
is: SBO:0000252
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_10484c5b_7a87_4edf_ad65_c0309229cabf
value: 0.0
type: LocalParameter

metaR r0765
is described by: http://identifiers.org/pubmed/7567999
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false
modifier: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (1892.1) or (1962.1) or (3030.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
name: Octanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_562dc6fd_2447_4424_a908_c1db30eecace
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f1b82fd0_df93_4858_bc10_20a0f1beb272
value: 1000.0
type: LocalParameter

metaR P5CDm
is described by: http://identifiers.org/pubmed/9700195
name: 1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
notes: GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Glutamate metabolism EC Number: 1.5.1.12 Confidence Level: 4 AUTHORS: PMID:8621661,PMID:9700195 NOTES: NCD
modifier: MODEL1109130000#
reversible: false
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/8621661
is version of: ECO:0000269
is version of: http://identifiers.org/ec-code/1.5.1.12
is: SBO:0000176
reactant: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_8545c16d_d5cd_4bd1_869b_4ba0d6249d91
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33b3cb94_b39a_4a90_90ec_900358db7168
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7c734c04_d96a_4828_883e_4264e5ccb951
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2cf0447_3524_420d_bf3e_04ce062fbff5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8862acdb_eb8f_48f8_a94f_9269671f4f19
initial concentration: NaN
boundary condition: true
initial amount: NaN
constant: false
is: Q59EA4
is: SBO:0000252
name: PLD1
type: Species
has only substance units: false
is encoded by: hsa:5337

http://identifiers.org/biomodels.db/MODEL1109130000#_8ed224bf_4fb4_412d_9b28_4231010eb54d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b1abe208_d25c_4aa4_a1f3_3f2ee81e7d96
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_54d20d0f_7ad6_4246_9df4_497489e1fd09
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3208bc92_51e2_491b_9eae_f65ec339b745
value: -1000.0
type: LocalParameter

metaR NACHEXA11ly
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12706724
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8993162
is: SBO:0000176
notes: GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Keratan sulfate degradation EC Number: Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: Note that this reaction is specific to beta-N-acetylhexosaminidase A and cannot be catalyzed by beta-N-acetylhexosaminidase B (or presumably beta-N-acetylhexosaminidase S). This is also a lumped reaction, representing the cleavage of GalNAc4S or GalNAc6S and N-acetylgalactosamine 4-sulfatase or 6-sulfatase. NCD
reversible: false
name: beta-N-acetylhexosaminidase A, lysosomal
is described by: http://identifiers.org/pubmed/11707436
product: MODEL1109130000#
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/10336991
fast: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#c896ae33_fffc_4018_ab21_4148892e4d18
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0766
notes: GENE_ASSOCIATION: (1892.1) or (1962.1) or (3030.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
modifier: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7567999
is described by: http://identifiers.org/pubmed/11750882
is: SBO:0000176
is described by: http://identifiers.org/pubmed/4452359
reversible: true
is described by: http://identifiers.org/pubmed/7834997
type: Reaction
is described by: http://identifiers.org/pubmed/8962082
name: Octanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/6137188
is version of: http://identifiers.org/ec-code/2.3.1.85

http://identifiers.org/biomodels.db/MODEL1109130000#_71db5954_a9e5_4a0e_b2c0_2cd60f1dc093
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1eeca637_94e7_401f_8712_dd49158298de
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0810dbd8_99c8_4f94_afdb_e6211603eeb9
value: 1000.0
type: LocalParameter

metaR EX cspg b LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S) proteoglycan exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_4c6f3001_87f9_47e8_aa46_145129e5a3aa
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1c30ad31_e320_4dc9_8379_956d709f63f5
value: 1000.0
type: LocalParameter

metaM 2c23dh56dhoxin c
name: 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
constant: false
is: SBO:0000247
is: http://identifiers.org/pubchem.substance/7927
initial concentration: 1.0
is: HMDB04067
notes: FORMULA: C9H8NO4 CHARGE: -1 INCHI: InChI=1/C9H9NO4/c11-7-2-4-1-6(9(13)14)10-5(4)3-8(7)12/h2-3,6,10-12H,1H2,(H,13,14)/t6-/m0/s1 EHMN_ABBREVIATION: C05604
has only substance units: false
is: C05604
boundary condition: false
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_d71b1ede_bbd5_484f_9b1a_a0c8de275f48
has part: P09110
type: Species
is encoded by: hsa:51
initial amount: NaN
is encoded by: hsa:1962
boundary condition: true
constant: true
is encoded by: hsa:30
is: SBO:0000297
name: EHHADH:ACAA1:ACOX1
initial concentration: NaN
has only substance units: false
has part: Q9NY65

http://identifiers.org/biomodels.db/MODEL1109130000#d1f167b4_1c12_4a35_8171_c13362892efb
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_02c53144_c5c1_4472_b43f_36ab599e8734
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b38e6f9e_ab4b_4f33_af16_6cee3b3ff4c9
has only substance units: false
initial amount: NaN
is encoded by: hsa:80864
is: Q99944
constant: true
boundary condition: true
initial concentration: NaN
is: SBO:0000252
type: Species
name: EGFL8

http://identifiers.org/biomodels.db/MODEL1109130000#_795269ce_2233_418e_ae9b_850ea470b99f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a3ee1f1_a7a8_43b1_87d2_fe9682ce68ee
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fa7b73b4_53de_47f9_9d96_b02a04a8f9f9
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3eb7e1db_71ba_4b44_bdaa_1ae167f4b700
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PFKL:PFKP
type: Species

metaR BZtr
fast: false
type: Reaction
name: Benzene transporter, endoplasmic reticulum
is: SBO:0000185
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 1 AUTHORS: NOTES: diffusion NJ
reversible: true
is version of: ECO:0000000

metaM CE6182 r
constant: false
notes: FORMULA: C41H59N7O21P3S CHARGE: -5 INCHI: InChI=1/C41H64N7O21P3S/c1-41(2,24-66-72(63,64)69-71(61,62)65-23-29-35(68-70(58,59)60)34(55)40(67-29)48-26-47-33-37(42)45-25-46-38(33)48)36(56)39(57)44-20-19-30(51)43-21-22-73-32(54)18-11-5-3-4-8-13-27(49)14-9-6-7-10-15-28(50)16-12-17-31(52)53/h4,6-10,14-15,25-29,34-36,40,49-50,55-56H,3,5,11-13,16-24H2,1-2H3,(H,43,51)(H,44,57)(H,52,53)(H,61,62)(H,63,64)(H2,42,45,46)(H2,58,59,60)/p-5/b7-6+,8-4-,14-9+,15-10-/t27-,28-,29-,34+,35+,36u,40-/m0/s1 EHMN_ABBREVIATION: CE6182
name: 20-CoA-20-oxo-leukotriene B4
boundary condition: false
has only substance units: false
is: SBO:0000247
initial amount: NaN
type: Species
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_486c06ab_b896_4cb7_b25b_7bbb0add2e1f
units: dimensionless
value: 0.0
type: LocalParameter

metaR DAG HSter
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 1 AUTHORS: NOTES:
product: MODEL1109130000#
reversible: false
fast: false
is: SBO:0000185
reactant: MODEL1109130000#
type: Reaction
name: diacylglycerol ER export

http://identifiers.org/biomodels.db/MODEL1109130000#_1a5cee4f_f2d2_413a_8f7e_ce6a79e48415
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_313168fe_e4b2_4eab_988e_5ccd7776826c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_878d3e8d_9e92_4c3a_b918_61633bac5f4e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4738b165_965c_469a_a965_c5e6a1587197
is: SBO:0000252
name: PFKFB4
boundary condition: true
initial concentration: NaN
is: Q16877
has only substance units: false
constant: false
is encoded by: hsa:5210
initial amount: NaN
type: Species

metaM gly e
type: Species
constant: false
notes: FORMULA: C2H5NO2 CHARGE: 0 INCHI:
boundary condition: false
name: Glycine
is: http://identifiers.org/pubchem.substance/3339
initial amount: NaN
is: C00037
has only substance units: false
is: HMDB00123
initial concentration: 1.0
is: SBO:0000247

metaM crtsl m
boundary condition: false
has only substance units: false
type: Species
is: CHEBI:17650
notes: FORMULA: C21H30O5 CHARGE: 0 INCHI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 EHMN_ABBREVIATION: C00735
is: HMDB00063
name: cortisol
initial amount: NaN
constant: false
is: SBO:0000247
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#f42626b9_7fbd_405a_94da_e951399ad45a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f62f07a5_e8a1_43ea_95de_98b937ae08c2
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a5bdbff5_2863_4db5_a441_1d872f1735e0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9876fc53_2eae_4f85_9df8_a3ff006f9fc7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18b79f1d_33a7_4468_a042_6e9cd47c6c7c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1b493e33_acab_4080_8f32_aa09f38841e6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d78a70a6_d462_45ff_bd8c_e499c5b1ea8e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d580eaa4_3a12_4bd6_8f7e_628f1800e91e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a5804ed4_650e_4b50_84b3_01ce10da1615
value: 1000.0
type: LocalParameter

metaM 3bcrn c
boundary condition: false
constant: false
has only substance units: false
type: Species
notes: FORMULA: C11H21NO5 CHARGE: 0
name: 3-hydroxy butyryl carnitine
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247

metaR EX 3mob LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: Exchange of 3-methyl-2-oxobutanoate
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_84eef74d_5981_4cd8_95e4_f4b250303376
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d9ff1a45_e2ad_495d_9dfe_bbf9f15a901b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b1f000d_bce8_4120_b0c9_c788fe97dafb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_721453df_620f_4fe8_996d_64070e81db6f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8a6397d_a636_4baa_b800_b5f859b3550b
value: -1000.0
type: LocalParameter

metaR ALAGLNNaEx
fast: false
name: L-alanine/L-glutamine Na-dependent exchange (Ala-L in)
type: Reaction
modifier: MODEL1109130000#
product: MODEL1109130000#
is version of: ECO:0000269
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 6510.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:14530974 NOTES: SAB see Kanai and Hediger 2004 (2003), PMID 14530974
is described by: http://identifiers.org/pubmed/14530974
is: SBO:0000185
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6eb8cf30_54c5_41c1_ad48_0a5c97d3603b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4bcc08a5_80a3_4602_91f4_018c35b1edeb
value: 0.0
type: LocalParameter

metaM 3hmp m
is: HMDB00023
has only substance units: false
initial amount: NaN
boundary condition: false
initial concentration: 1.0
constant: false
is: CHEBI:11805
notes: FORMULA: C4H7O3 CHARGE: -1 INCHI: InChI=1S/C4H8O3/c1-3(2-5)4(6)7/h3,5H,2H2,1H3,(H,6,7)/p-1 HEPATONET_1.0_ABBREVIATION: HC00705 EHMN_ABBREVIATION: C01188
is: SBO:0000247
name: 3-hydroxy-2-methylpropanoate
type: Species

metaR NACHEXA20ly
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Keratan sulfate degradation EC Number: Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: Note that this reaction is specific to beta-N-acetylhexosaminidase A and cannot be catalyzed by beta-N-acetylhexosaminidase B (or presumably beta-N-acetylhexosaminidase S). This is also a lumped reaction, representing the cleavage of GalNAc4S or GalNAc6S and N-acetylgalactosamine 4-sulfatase or 6-sulfatase. NCD
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11707436
is described by: http://identifiers.org/pubmed/10336991
type: Reaction
is described by: http://identifiers.org/pubmed/8993162
fast: false
is: SBO:0000176
is described by: http://identifiers.org/pubmed/12706724
is version of: ECO:0000000
reactant: MODEL1109130000#
name: beta-N-acetylhexosaminidase A, lysosomal
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#ba4e4575_0a22_4a73_a2e6_493f0824cd52
units: dimensionless
value: 0.0
type: LocalParameter

metaR FAOXC163GC142m
is described by: http://identifiers.org/pubmed/20195903
product: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/20490924
fast: false
name: fatty acid beta oxidation(C16:3-->C14:2)gm
reversible: false
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID:20195903, PMID:20490924, international journal of molecular medicine 19: 81-87, 2007. EC Number: NOTES: GENE_ASSOCIATION: (3030.1 and 3032.1)
modifier: MODEL1109130000#
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_6c2199e2_ef63_4dae_8f09_e14294397847
value: -1000.0
type: LocalParameter

metaR FAOXC121C101m
reversible: false
is: SBO:0000176
reactant: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID:20195903, PMID:20490924, international journal of molecular medicine 19: 81-87, 2007. EC Number: NOTES: mitochondrial beta oxidation GENE_ASSOCIATION: (34.1 and 1892.1 and 3033.1 and 10449.1)
modifier: MODEL1109130000#
fast: false
name: fatty acid beta oxidation(C12:1-->C10:1)m
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/20490924
is described by: http://identifiers.org/pubmed/20195903
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#f3d8add8_b622_456b_9d03_0ced8ae4867f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d5385326_ee26_4b54_9942_3728fb703991
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_75a22945_3191_411b_a7b9_4bb6d67a2d73
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2b61f2fa_777b_467e_9649_39cf69c435c1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b0b5b2fb_9622_49ab_add3_b05c1b8e6947
value: -1000.0
type: LocalParameter

metaM decdicrn e
name: decadienoyl carnitine
initial amount: NaN
type: Species
is: HMDB13325
initial concentration: 1.0
is: SBO:0000247
constant: false
has only substance units: false
notes: FORMULA: C17H29NO4 CHARGE: 0
boundary condition: false

metaM 3bcrn e
name: 3-hydroxy butyryl carnitine
initial concentration: 1.0
type: Species
boundary condition: false
has only substance units: false
initial amount: NaN
notes: FORMULA: C11H21NO5 CHARGE: 0
constant: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_536479ef_3313_4d10_b21c_484c8c0e5b3b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2dc08223_c252_4413_ac12_829bec5d0157
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1b6f6d64_a3fb_4802_979a_08e39785ac54
boundary condition: true
constant: false
initial concentration: NaN
is: SBO:0000252
is encoded by: hsa:1636
type: Species
has only substance units: false
is: B4DKH4
initial amount: NaN
name: ACE

http://identifiers.org/biomodels.db/MODEL1109130000#db6647b5_c8a6_459d_a761_37714392925d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d098f406_4c32_4142_bb42_63eb5855817d
value: 0.0
type: LocalParameter

metaM thyox L r
initial concentration: 1.0
constant: false
is: SBO:0000247
notes: FORMULA: C15H11I4NO4 CHARGE: 0 INCHI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00849
is: HMDB00248
boundary condition: false
initial amount: NaN
name: L-thyroxine
type: Species
has only substance units: false
is: CHEBI:18332

http://identifiers.org/biomodels.db/MODEL1109130000#e308fd1a_06d4_4fde_b243_c5f486f4b4e3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_41f0d89d_6f73_4114_b8bb_ea17fe27acf7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bffb44e7_6efd_4b4d_b9b4_bd576ece361f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_37cc5559_7f7d_4a3b_8db5_b78318ff5504
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8345d1ab_6616_4227_b3d4_20c8f38cb0a6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#edec82e8_3b74_46e9_b1c5_7404fe368aab
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3ec90f00_adf5_4301_a52b_f2c02d2438b0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b9068305_fae9_49a1_b511_f3a37df2fea1
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#d8603ee9_67e1_4e67_8ce8_2931682f1beb
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

metaM HC00007 c
name: ApoC2
type: Species
initial concentration: 1.0
constant: false
is: SBO:0000247
boundary condition: false
has only substance units: false
notes: FORMULA: CHARGE: 0 INCHI:
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_24b2d18f_7618_46c5_bd46_9f3dec108899
units: dimensionless
value: 0.0
type: LocalParameter

metaM decdicrn c
initial concentration: 1.0
initial amount: NaN
has only substance units: false
name: decadienoyl carnitine
is: SBO:0000247
notes: FORMULA: C17H29NO4 CHARGE: 0
boundary condition: false
constant: false
is: HMDB13325
type: Species

metaM gly c
boundary condition: false
name: Glycine
notes: FORMULA: C2H5NO2 CHARGE: 0 INCHI:
constant: false
type: Species
has only substance units: false
is: http://identifiers.org/pubchem.substance/3339
initial amount: NaN
initial concentration: 1.0
is: C00037
is: HMDB00123
is: SBO:0000247

metaR RE2154C
is version of: http://identifiers.org/ec-code/1.1.1.50
name: RE2154
is described by: http://identifiers.org/pubmed/12416991
fast: false
is: SBO:0000176
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Miscellaneous EC Number: 1.1.1.50 Confidence Level: 0 AUTHORS: PMID:12416991 NOTES:
type: Reaction
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_0edca2b8_5319_4fe6_9b42_58afe635293c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f73f61cb_0931_48ef_b59b_21e73b445a6a
value: -1000.0
type: LocalParameter

metaM m6masnA g
notes: FORMULA: C58H97N2O45X CHARGE: 0 INCHI:
type: Species
is: SBO:0000247
initial amount: NaN
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
boundary condition: false
has only substance units: false
constant: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_175238c3_cb33_4dcd_bee3_655bf7ae7342
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9bee5187_99ee_4540_81fd_c2508adb036b
value: -1000.0
type: LocalParameter

metaM CE5547 x
is: SBO:0000247
has only substance units: false
notes: FORMULA: C18H23N4O9S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5547
initial concentration: 1.0
boundary condition: false
type: Species
name: 5-S-glutathionyl-noradrenochrome hydroquinone
constant: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#c7a34a37_ed2a_460f_8489_11a311672b81
value: 0.0
type: LocalParameter

metaR SUCCtp
name: succinate transporter, peroxisome
type: Reaction
reversible: true
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 0 AUTHORS: NOTES: unknown mechanism NJ
reactant: MODEL1109130000#
is version of: ECO:0000000
fast: false
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_00707db4_2512_4e09_aaf2_a73bf1ac5791
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e3a58df4_7434_47a9_9d9d_630de768a117
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0c2bfc49_d1cc_44bc_9e66_85d500878d11
value: 1000.0
type: LocalParameter

metaM xtsn c
constant: false
initial concentration: 1.0
type: Species
boundary condition: false
notes: FORMULA: C10H12N4O6 CHARGE: 0 INCHI: InChI=1S/C10H12N4O6/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19)/t3-,5-,6-,9-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00838 EHMN_ABBREVIATION: C01762
initial amount: NaN
is: CHEBI:18107
has only substance units: false
is: HMDB00299
is: SBO:0000247
name: xanthosine

http://identifiers.org/biomodels.db/MODEL1109130000#_8916e3b8_b956_48aa_bc90_6ecaa7b4f2f7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_metaM_acgalfucgalacgalfucgalacglcgal14acglcgalgluside_hs_e
initial amount: NaN
is: SBO:0000247
name: Type IIIAb
notes: FORMULA: C92H158N5O55FULLRCO CHARGE: 0 INCHI:
boundary condition: false
has only substance units: false
constant: false
initial concentration: 1.0
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_31ecf403_a4e9_4874_b353_54262a4eeb09
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2a13e621_2d5c_4a1a_b5b2_7e78e7513bfd
is: Q06136
type: Species
name: KDSR
initial concentration: NaN
is: SBO:0000252
is encoded by: hsa:2531
has only substance units: false
boundary condition: true
constant: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#ea2006e0_af4d_4770_8bea_d85eaf9e512c
value: -1000.0
type: LocalParameter

metaR GCHOLAt3
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/9806540
type: Reaction
name: ABC bile acid transporter
modifier: MODEL1109130000#
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9738950
is: SBO:0000185
notes: GENE_ASSOCIATION: (8714.3) or (8647.1) or (8714.2) or (8714.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:9738950,PMID:9806540,PMID:9813153 NOTES: for bile acid secretion into bile NJ
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9813153
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_283c45d0_93fa_4ea8_bf0d_2304cae14a58
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d7307456_c755_418e_99c7_5e485b56e1b9
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3128fc9f_e37c_466e_88e1_fcfbae3b5d36
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ff802499_9b80_4e14_bddd_1684b9e94c4e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_807d254a_9503_422a_87ae_9e1800329e2e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c3b9d8dc_3f60_4291_816f_d63ec4de9314
units: dimensionless
value: 0.0
type: LocalParameter

metaR GCHOLAt2
is described by: http://identifiers.org/pubmed/8132774
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7592981
is described by: http://identifiers.org/pubmed/9109432
notes: GENE_ASSOCIATION: (6554.1) or (6555.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:12851823,PMID:7592981,PMID:8132774,PMID:9109432 NOTES: electrogenic uptake NJ
type: Reaction
fast: false
name: glycocholate transport via sodium cotransport
product: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12851823
is version of: ECO:0000269
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_54eedeae_2156_45b4_8073_0a8014ff63d1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8e796ca1_735b_4542_afaf_55d7ee340a79
value: 0.0
type: LocalParameter

metaM C02528 m
type: Species
notes: FORMULA: C24H39O4 CHARGE: -1 INCHI: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00958 EHMN_ABBREVIATION: C02528
name: chenodeoxycholate
boundary condition: false
initial concentration: 1.0
is: HMDB00518
is: CHEBI:36234
is: SBO:0000247
constant: false
initial amount: NaN
has only substance units: false

metaR RE0512X
reactant: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7846063
notes: GENE_ASSOCIATION: (3295.1) or (1962.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:7846063 NOTES:
is: SBO:0000176
fast: false
is version of: http://identifiers.org/ec-code/1.1.1.35
reversible: true
name: RE0512
modifier: MODEL1109130000#

metaM h r
has only substance units: false
initial amount: NaN
type: Species
initial concentration: 1.0
name: proton
is: http://identifiers.org/pubchem.substance/3380
is: C00080
notes: FORMULA: H CHARGE: 1 HEPATONET_1.0_ABBREVIATION: HC00083 EHMN_ABBREVIATION: C00080 INCHI: InChI=1S/p+1/i/hH
is: SBO:0000247
boundary condition: false
constant: false
is: CHEBI:24636

http://identifiers.org/biomodels.db/MODEL1109130000#_4093153b_5d85_4f2a_9014_a4d89da55de3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6e6bfa44_9f3e_490d_b391_f3b4e97ade6d
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_32c93ee7_9e44_4d83_8edc_158dc917097f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1087e65d_25e8_4293_8c06_037a87261b9e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6d134f90_c20a_4d5d_adff_ee499578c190
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d8801f5d_e132_419c_9fe0_f6d06184514b
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX HC02207 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: prostaglandin-c2 exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_metaM_acgalfucgalacgalfucgalacglcgal14acglcgalgluside_hs_g
boundary condition: false
constant: false
is: SBO:0000247
type: Species
notes: FORMULA: C92H158N5O55FULLRCO CHARGE: 0 INCHI:
has only substance units: false
initial amount: NaN
name: Type IIIAb
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_3b729627_db9a_4f04_a994_aa6e7616fc0e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0ae63ab7_8cf1_4a42_a04a_96a8d559ea57
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#af10a077_6383_48ba_81b8_908baa13d7e0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_34d0e48f_bdf6_42ee_a0ca_0d09cb85f036
units: dimensionless
value: 0.0
type: LocalParameter

metaR LIMNENte
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES: unknown mechanism, xenobiotic transport (original and metabolized) NJ
reversible: true
product: MODEL1109130000#
fast: false
is: SBO:0000185
name: xenobiotic transport
is version of: ECO:0000000
reactant: MODEL1109130000#
type: Reaction

metaM 3hbcoa R m
initial amount: NaN
name: (R)-3-hydroxybutanoyl-CoA(4-)
has only substance units: false
initial concentration: 1.0
type: Species
constant: false
boundary condition: false
is: SBO:0000247
is: CHEBI:57315
notes: FORMULA: C25H38N7O18P3S CHARGE: -4 INCHI: InChI=1S/C25H42N7O18P3S/c1-13(33)8-16(35)54-7-6-27-15(34)4-5-28-23(38)20(37)25(2,3)10-47-53(44,45)50-52(42,43)46-9-14-19(49-51(39,40)41)18(36)24(48-14)32-12-31-17-21(26)29-11-30-22(17)32/h11-14,18-20,24,33,36-37H,4-10H2,1-3H3,(H,27,34)(H,28,38)(H,42,43)(H,44,45)(H2,26,29,30)(H2,39,40,41)/p-4/t13-,14-,18-,19-,20+,24-/m1/s1
is: HMDB01166

http://identifiers.org/biomodels.db/MODEL1109130000#_4626edf4_cb4d_4ece_b99e_83cebf62641f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5f9c1dfa_8c21_497e_b164_0a2b59c924c0
value: 0.0
type: LocalParameter

metaR DOLASNT Ler
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: (6185.1 and 1650.1 and 6184.1 and 1603.1) SUBSYSTEM: N-glycan synthesis EC Number: 2.4.1.119 Confidence Level: 0 AUTHORS: NOTES: NCD
reversible: false
name: Dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase (liver)
is version of: ECO:0000000
modifier: MODEL1109130000#
is: SBO:0000176
type: Reaction
is version of: http://identifiers.org/ec-code/2.4.1.119

http://identifiers.org/biomodels.db/MODEL1109130000#_778f8224_1691_4c59_8c59_6b845b1623ad
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_70ca23bc_e6d2_4156_a347_cbcd32a6aa4e
value: 1000.0
type: LocalParameter

metaR CSPG At
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES:
reactant: MODEL1109130000#
type: Reaction
is: SBO:0000185
fast: false
reversible: false
is version of: ECO:0000000
name: chondroitin sulfate A transport, golgi to extracellular

http://identifiers.org/biomodels.db/MODEL1109130000#_f7733362_f4e5_4b6d_b0e2_8c30d3ed9007
initial amount: NaN
name: ST6GALNAC3
is: Q8NDV1
is: SBO:0000252
initial concentration: NaN
constant: false
type: Species
has only substance units: false
is encoded by: hsa:256435
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#f8682d30_c497_41a1_80ab_cd802e5b2923
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_26e68f0a_f877_4258_9f83_72f57d796e2b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_91b446c7_487c_4e7a_a223_a1296d2581ad
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a572c8c3_6f3a_450f_a8b3_a02c5289f142
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_06dacaef_6b1f_4c29_9167_5b3fd7046507
value: 1000.0
type: LocalParameter

metaR RE2335C
is described by: http://identifiers.org/pubmed/10047787
is described by: http://identifiers.org/pubmed/7040832
notes: GENE_ASSOCIATION: SUBSYSTEM: Urea cycle EC Number: Confidence Level: 0 AUTHORS: PMID:10047787,PMID:7040832 NOTES:
is: SBO:0000176
fast: false
reversible: true
name: RE2335
product: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#b9b534fd_ef74_4b8b_9da9_2cd92fb892b8
value: -1000.0
type: LocalParameter

metaR FAOXC18480m
is: SBO:0000176
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (34.1) or (35.1) SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.74 Confidence Level: 4 AUTHORS: NOTES: _5 rounds of beta ox, 4 degrees loss of saturation -> only 1 fad oxidized to fadh2 peroxisomal (very long chain FA) c18:4,n-6 -> c8:0, 4 step FAO lumped for 2 rounds also includes EC 1.1.1.35, 1.1.1.211, 1.3.3.6, 4.2.1.17, 4.2.1.74 NJ
name: Beta oxidation of fatty acid
type: Reaction
reversible: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/4.2.1.74
reactant: MODEL1109130000#
fast: false
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_82422112_bb8c_41a0_9a7e_ce066a69b21d
is: SBO:0000252
constant: false
boundary condition: true
has only substance units: false
initial amount: NaN
initial concentration: NaN
type: Species
name: MDH1B
is: Q5I0G3
is encoded by: hsa:130752

http://identifiers.org/biomodels.db/MODEL1109130000#ceacab00_79ef_404e_986c_4291389c06cb
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_729a3ed4_fa5c_45d3_9be6_94ab9b2fec7a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7a384677_8f4f_489b_af9a_d7f13af4bfbb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ce856c0e_9412_49e7_9ed2_8081845ff4bb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_473182e3_7505_4065_9c04_f1109a7d201a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ba3756e9_87b5_4b0d_ba91_78ef4442d640
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ff4e2c32_b920_4e33_adec_1d4a30704e51
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f1fc3c2d_f03b_41f3_85ee_72fd79a43efe
value: 1000.0
type: LocalParameter

metaM CE5343 c
notes: FORMULA: C20H31O4 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5343
has only substance units: false
is: SBO:0000247
initial concentration: 1.0
boundary condition: false
initial amount: NaN
type: Species
name: 6,7-dihydro-5-oxo-12-epi-leukotriene B
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_55d85561_1df5_46a3_9ab5_5b0fde064bbe
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6ed9e1b4_f0a3_40b6_bfa1_2e1b482f69dc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_eedaf16d_29f7_4c31_9dca_0cbe728602de
boundary condition: true
is encoded by: hsa:3948
has only substance units: false
initial amount: NaN
is: SBO:0000252
constant: false
name: LDHC
type: Species
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_6c53b67c_96fd_4a80_a818_b3daa4ae731a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6b220c3c_d059_4693_be04_00391aab4e58
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE4818 c
has only substance units: false
type: Species
initial amount: NaN
constant: false
boundary condition: false
is: SBO:0000247
name: 3(S)-hydroxy-tetracosa-9,12,15,18,21-all-cis-pentaenoyl-CoA
initial concentration: 1.0
notes: FORMULA: C45H68N7O18P3S CHARGE: -4 INCHI: InChI=1/C45H72N7O18P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-33(53)28-36(55)74-27-26-47-35(54)24-25-48-43(58)40(57)45(2,3)30-67-73(64,65)70-72(62,63)66-29-34-39(69-71(59,60)61)38(56)44(68-34)52-32-51-37-41(46)49-31-50-42(37)52/h5-6,8-9,11-12,14-15,17-18,31-34,38-40,44,53,56-57H,4,7,10,13,16,19-30H2,1-3H3,(H,47,54)(H,48,58)(H,62,63)(H,64,65)(H2,46,49,50)(H2,59,60,61)/p-4/b6-5-,9-8-,12-11-,15-14-,18-17-/t33-,34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4818

http://identifiers.org/biomodels.db/MODEL1109130000#cda0d4e8_c6c5_4c88_bfa9_2304c6098d5d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4de5b38b_dbda_4aed_89bc_8193c11297e9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ce743bb0_25dd_4fea_b0c7_71b2e39987cf
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a33dca0_019a_4a93_adb1_10de046d3e26
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_metaM_acgalfucgalacgalfucgalacglcgal14acglcgalgluside_hs_c
constant: false
boundary condition: false
notes: FORMULA: C92H158N5O55FULLRCO CHARGE: 0 INCHI:
initial amount: NaN
type: Species
name: Type IIIAb
initial concentration: 1.0
has only substance units: false
is: SBO:0000247

metaM adprib m
is: CHEBI:57967
constant: false
initial concentration: 1.0
initial amount: NaN
is: HMDB01178
boundary condition: false
has only substance units: false
is: SBO:0000247
notes: FORMULA: C15H21N5O14P2 CHARGE: -2 INCHI: InChI=1S/C15H23N5O14P2/c16-12-7-13(18-3-17-12)20(4-19-7)14-10(23)8(21)5(32-14)1-30-35(26,27)34-36(28,29)31-2-6-9(22)11(24)15(25)33-6/h3-6,8-11,14-15,21-25H,1-2H2,(H,26,27)(H,28,29)(H2,16,17,18)/p-2/t5-,6-,8-,9-,10-,11-,14-,15?/m1/s1 EHMN_ABBREVIATION: C00301
type: Species
name: D-ribofuranos-5-yl-ADP(2-)

http://identifiers.org/biomodels.db/MODEL1109130000#_33ba99e0_19bf_4ad2_8908_9b5b12a11a99
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3ca2ed10_718b_4d06_bd65_15c6a9fd6ce8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4d57beb5_c58a_474b_bd6a_110416b3915b
value: 0.0
type: LocalParameter

metaM C02528 r
initial amount: NaN
has only substance units: false
boundary condition: false
is: CHEBI:36234
is: SBO:0000247
constant: false
notes: FORMULA: C24H39O4 CHARGE: -1 INCHI: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00958 EHMN_ABBREVIATION: C02528
name: chenodeoxycholate
is: HMDB00518
type: Species
initial concentration: 1.0

metaR EX gumtchol LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for guar gum-taurocholic acid complex
type: Reaction

metaR B3GALT44g
fast: false
reversible: false
reactant: MODEL1109130000#
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 8705.1 SUBSYSTEM: Sphingolipid metabolism EC Number: 2.4.1.62 Confidence Level: 4 AUTHORS: NOTES: NJ
name: Beta-1,3-galactosyltransferase 4
is: SBO:0000176
is version of: ECO:0000269
is version of: http://identifiers.org/ec-code/2.4.1.62
product: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_4a92f9a6_0ae0_4241_9bfd_c040cb10230e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f52781be_1909_4327_a120_0f5250812ac4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a363d0ac_9655_4804_8685_ccff44600578
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ae40e216_f575_4ba7_b911_a3e6ac8db028
name: SLC27A2
boundary condition: true
is: SBO:0000252
initial concentration: NaN
constant: false
type: Species
initial amount: NaN
has only substance units: false
is: O14975
is encoded by: hsa:11001

http://identifiers.org/biomodels.db/MODEL1109130000#df827140_eb0a_487b_ad7e_aff44d68d527
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_48f5547d_a32a_4d56_89ed_de76bb32eb3e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_81af2a4f_88a6_470b_bad7_f7ad8c2fa135
value: 1000.0
type: LocalParameter

metaR EX strch2 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]})
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#eea629df_9c81_4e8d_83bf_c41bf4a2765b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_bb5aca61_894d_4ff8_86c4_aaf96e0307e4
is: GO:0005634
is: SBO:0000290
constant: false
size: 1.0
spatial dimensions: 3.0
name: nucleus
type: Compartment

http://identifiers.org/biomodels.db/MODEL1109130000#_3bca16d7_df31_4d97_adc5_b5b4050f706b
value: -1000.0
type: LocalParameter

metaM CE0713 c
is: SBO:0000247
boundary condition: false
type: Species
notes: FORMULA: C39H60N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE0713
initial amount: NaN
name: 3-oxolinoleoyl-CoA
initial concentration: 1.0
has only substance units: false
constant: false

metaM h x
is: SBO:0000247
boundary condition: false
constant: false
is: CHEBI:24636
initial amount: NaN
has only substance units: false
initial concentration: 1.0
type: Species
notes: FORMULA: H CHARGE: 1 HEPATONET_1.0_ABBREVIATION: HC00083 EHMN_ABBREVIATION: C00080 INCHI: InChI=1S/p+1/i/hH
is: http://identifiers.org/pubchem.substance/3380
name: proton
is: C00080

http://identifiers.org/biomodels.db/MODEL1109130000#_4b488140_467c_4d3b_a151_af56dd398483
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f9cafa22_a35e_449d_a506_495c71f1eb03
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31f9785f_d191_429e_80cb_52dcdb2d4de1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2ae838c9_a0ba_47c7_87b0_053773f8cdd4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b16295f8_de60_4999_b8ba_5518d175d97f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0ebbc86e_b3ea_433e_a357_a7407fda71c6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_52eda23f_d5ae_47ad_b9dd_2e2d815e9f98
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7524721e_83a9_4f47_8cfd_36b3be15f00e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5dd2936b_97e7_4b94_87a9_ebf53a5b8fc8
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0772
is described by: http://identifiers.org/pubmed/7834997
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11750882
is described by: http://identifiers.org/pubmed/7567999
notes: GENE_ASSOCIATION: (1962.1) or (3033.1) or (3030.1) or (3028.1) or (3295.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false
modifier: MODEL1109130000#
name: Tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
is: SBO:0000176
type: Reaction
reversible: true
is described by: http://identifiers.org/pubmed/8962082
is described by: http://identifiers.org/pubmed/4452359
is described by: http://identifiers.org/pubmed/6137188
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_493b0299_6e07_44e7_9fee_bf2c830cde2a
type: Species
is: SBO:0000252
initial amount: NaN
is encoded by: hsa:27068
has only substance units: false
initial concentration: NaN
name: PPA2
constant: true
boundary condition: true
is: Q9H2U2

metaM orot5p c
is: HMDB00218
is: CHEBI:57538
initial concentration: 1.0
type: Species
boundary condition: false
has only substance units: false
is: SBO:0000247
notes: FORMULA: C10H10N2O11P CHARGE: -3 HEPATONET_1.0_ABBREVIATION: HC00669 EHMN_ABBREVIATION: C01103 INCHI: InChI=1S/C10H13N2O11P/c13-5-1-3(9(16)17)12(10(18)11-5)8-7(15)6(14)4(23-8)2-22-24(19,20)21/h1,4,6-8,14-15H,2H2,(H,16,17)(H,11,13,18)(H2,19,20,21)/p-3/t4-,6-,7-,8-/m1/s1
is: C01103
initial amount: NaN
constant: false
name: Orotidine 5-phosphate

http://identifiers.org/biomodels.db/MODEL1109130000#_54062262_c186_4930_b872_8458f136b070
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2b40a396_127c_41eb_bca3_2b0878625a1b
value: -1000.0
type: LocalParameter

metaM adprib c
boundary condition: false
is: CHEBI:57967
is: HMDB01178
initial concentration: 1.0
is: SBO:0000247
is: C00301
name: ADPribose
type: Species
constant: false
notes: FORMULA: C15H21N5O14P2 CHARGE: -2 EHMN_ABBREVIATION: C00301 INCHI: InChI=1S/C15H23N5O14P2/c16-12-7-13(18-3-17-12)20(4-19-7)14-10(23)8(21)5(32-14)1-30-35(26,27)34-36(28,29)31-2-6-9(22)11(24)15(25)33-6/h3-6,8-11,14-15,21-25H,1-2H2,(H,26,27)(H,28,29)(H2,16,17,18)/p-2/t5-,6-,8-,9-,10-,11-,14-,15?/m1/s1
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_0b79a43f_f910_44bc_8d22_17eb587169b7
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ac9f29ea_2538_46a5_bbd9_63fdb3d7b25c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ef6fa892_2beb_4809_9404_7eaa3d509a26
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2e2ce777_d546_4e1a_868b_e7872b1cc1db
value: 0.0
type: LocalParameter

metaR CARhPTtc
is described by: http://identifiers.org/pubmed/17681807
is described by: http://identifiers.org/pubmed/16289537
fast: false
is: SBO:0000185
type: Reaction
name: Transport of L-Carnosine by hPT3 or hPT4 peptide transporter.
reversible: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12905028
modifier: MODEL1109130000#
notes: SUBSYSTEM: Transport, lysosomal Confidence Level: 4 AUTHORS: PMID: 16289537, PMID: 12905028, PMID: 17681807 EC Number: NOTES: hPT3 (human peptide transporter 3) transports histidine and di-peptides from the lysosomes into the cytosol. Co-transports proton, expressed in lung, thymus, spleen and faintly in brain, placenta, liver, adrenal gland and heart (PMID: 12905028). hPT4 expressed in brain, placenta and retina. Transports carnosine and histidine in a proton symport mechanism. (PMID: 12905028). GENE_ASSOCIATION: (51296.1 or 121260.1)
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_1e3bbdc3_5800_4ac7_a45d_1a3f0c0002bf
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_21590c5c_029b_4c15_bfec_626b9dfbed00
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_05c45e30_7c2a_4b25_ad01_ebf8a53e2b5b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a87bada2_2302_4103_9314_f7e0b577f7f5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_756df8aa_7e3b_446c_935d_68e5ddfdfdce
value: 0.0
type: LocalParameter

metaM CE5797 c
initial amount: NaN
boundary condition: false
constant: false
is: SBO:0000247
name: neuromedin N
initial concentration: 1.0
notes: FORMULA: C32H51N5O7 CHARGE: 0 INCHI: EHMN_ABBREVIATION: CE5797
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4a391ed2_0bea_4393_99f8_ae7d293f86b1
value: 0.0
type: LocalParameter

metaR r0771
fast: false
is version of: http://identifiers.org/ec-code/2.3.1.85
product: MODEL1109130000#
modifier: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (1962.1) or (3033.1) or (3030.1) or (3028.1) or (3295.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
name: Tetradecanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
is described by: http://identifiers.org/pubmed/7567999
is: SBO:0000176
type: Reaction
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#f584905f_338e_4d78_ad5c_a1e4bd68b179
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_109987b8_881a_4d32_ae1c_22e2610177a8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7436fc4d_fbdf_47de_a43b_23e3c77c8849
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c0f935eb_c6cf_4764_9f00_27d6c662dbf3
value: 1000.0
type: LocalParameter

metaR TYRPHELAT2tc
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/200
name: transport of L-Tyrosine into the cell and efflux of L-Phenylalanine out of the cell by LAT2 on the basolateral surfaces of kidney and intestine.
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10574970
is described by: http://identifiers.org/pubmed/18195088
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: Pflugers Arch-Eur J Physiol (2000) 440:503-512 DOI 10.1007/s00420000274, PMID: 10574970, J Am Soc Nephrol 14: 837?847, 200, Pflugers Arch-Eur J Physiol (2003) 445:529-533 DOI 10.1007/s00424-002-0973-z, PMID: 18195088, Am J Physiol (2001) 281:C1077-C1093. EC Number: NOTES: higer affinity for small neutral amino acids that LAT1, functions as exchanger (antiport system), at the basolateral surface of memebranes in transporting epithelia. Localized in the proximal tubule of kidney, small intestine. Lesser expression in ivary, placenta and brain. Heterodimerization with CD-98 for traficking of the complex to the mebrane. (Pflugers Arch-Eur J Physiol (2000) 440:503-512 DOI 10.1007/s00420000274). GENE_ASSOCIATION: (23428.1 and 6520.1)
reversible: false
modifier: MODEL1109130000#
fast: false
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_1cc1b823_1ecc_455c_bd6d_404c12d76ee8
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a136823_a512_4aed_8b1d_9a6d7c2575ce
is encoded by: hsa:3418
is: P48735
type: Species
constant: false
initial amount: NaN
name: IDH2
is: SBO:0000252
initial concentration: NaN
has only substance units: false
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_0b337637_2fc4_4d25_b454_9408332f12ac
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7d284501_1637_4aa5_b628_35428f67b8bf
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_182461e1_ee23_4693_b1fd_3e21ea741a92
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_01286796_04b1_44fb_840b_5eed50ce7806
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_570613e5_e979_4e91_be96_3b70077d75d6
units: dimensionless
value: 0.0
type: LocalParameter

metaR ELAIDCPT2
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: NOTES: NJ
type: Reaction
is: SBO:0000176
reactant: MODEL1109130000#
is version of: ECO:0000000
reversible: false
name: carnitine transferase
fast: false
modifier: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_5d0a8f2b_39c4_4863_b2bf_b49f5a0ac1fa
value: 0.0
type: LocalParameter

metaR EX gumgchol LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for guar gum-glycocholate complex
type: Reaction

metaR r0774
reactant: MODEL1109130000#
fast: false
is: SBO:0000176
type: Reaction
notes: GENE_ASSOCIATION: (1962.1) or (3033.1) or (3030.1) or (3028.1) or (3295.1) SUBSYSTEM: Unassigned EC Number: 4.1.1.37 Confidence Level: 0 AUTHORS: PMID:17360334 NOTES:
modifier: MODEL1109130000#
name: Uroporphyrinogen I carboxy-lyase Porphyrin and chlorophyll metabolism EC:4.1.1.37
reversible: true
is described by: http://identifiers.org/pubmed/17360334
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/4.1.1.37

http://identifiers.org/biomodels.db/MODEL1109130000#_6a4e871c_812a_4818_9058_751cd34e23ca
value: 0.0
type: LocalParameter

metaM CE4818 r
name: 3(S)-hydroxy-tetracosa-9,12,15,18,21-all-cis-pentaenoyl-CoA
is: SBO:0000247
type: Species
notes: FORMULA: C45H68N7O18P3S CHARGE: -4 INCHI: InChI=1/C45H72N7O18P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-33(53)28-36(55)74-27-26-47-35(54)24-25-48-43(58)40(57)45(2,3)30-67-73(64,65)70-72(62,63)66-29-34-39(69-71(59,60)61)38(56)44(68-34)52-32-51-37-41(46)49-31-50-42(37)52/h5-6,8-9,11-12,14-15,17-18,31-34,38-40,44,53,56-57H,4,7,10,13,16,19-30H2,1-3H3,(H,47,54)(H,48,58)(H,62,63)(H,64,65)(H2,46,49,50)(H2,59,60,61)/p-4/b6-5-,9-8-,12-11-,15-14-,18-17-/t33-,34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4818
constant: false
has only substance units: false
initial amount: NaN
boundary condition: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_36adbdbb_6e44_4d4b_a5c9_7ec34efe73ce
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a36bdc26_4d9a_499e_8279_6714bac3f294
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2a5f4cd7_d059_4587_969e_0fc79333d5c7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_f9849ff9_dea1_45ff_aee8_dc33a89cff58
boundary condition: true
name: SYNJ1
is: SBO:0000252
is: C9JFZ1
is encoded by: hsa:8867
initial amount: NaN
type: Species
constant: true
initial concentration: NaN
has only substance units: false

metaM h l
is: CHEBI:24636
boundary condition: false
initial amount: NaN
notes: FORMULA: H CHARGE: 1 INCHI: InChI=1S/p+1/i/hH
is: C00080
constant: false
initial concentration: 1.0
name: proton
is: SBO:0000247
is: http://identifiers.org/pubchem.substance/3380
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_24cf12e8_883a_45b2_b87a_40af67c06b61
initial amount: NaN
has only substance units: false
name: PECR
is encoded by: hsa:55825
constant: false
is: Q9BY49
type: Species
boundary condition: true
initial concentration: NaN
is: SBO:0000252

metaR LTA4H
is version of: http://identifiers.org/ec-code/3.3.2.6
notes: GENE_ASSOCIATION: 4048.1 SUBSYSTEM: Eicosanoid metabolism EC Number: 3.3.2.6 Confidence Level: 4 AUTHORS: PMID:7918238 NOTES: NJ
reactant: MODEL1109130000#
fast: false
is: SBO:0000176
name: Leukotriene A-4 hydrolase
is described by: http://identifiers.org/pubmed/7918238
is version of: ECO:0000134
reversible: false
product: MODEL1109130000#
type: Reaction
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_860de443_3221_4f97_a7a2_5280bdaae6da
value: 1000.0
type: LocalParameter

metaM C02528 x
notes: FORMULA: C24H39O4 CHARGE: -1 INCHI: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00958 EHMN_ABBREVIATION: C02528
initial amount: NaN
initial concentration: 1.0
type: Species
is: SBO:0000247
has only substance units: false
boundary condition: false
is: CHEBI:36234
name: chenodeoxycholate
is: HMDB00518
constant: false

metaR ELAIDCPT1
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.21
reversible: false
fast: false
modifier: MODEL1109130000#
type: Reaction
is: SBO:0000176
notes: GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: NOTES: NJ
is version of: ECO:0000269
reactant: MODEL1109130000#
name: carnitine O-palmitoyltransferase

http://identifiers.org/biomodels.db/MODEL1109130000#_7ab89008_b3c8_4787_8383_d69c43275379
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_37783fd6_f6a3_4815_ab79_5df2011c4e8b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a358b86c_ea47_4839_99b3_e2e4f61382f4
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0773
reversible: true
fast: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.85
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7567999
is: SBO:0000176
type: Reaction
name: Hexadecanoyl-[acyl-carrier protein:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
notes: GENE_ASSOCIATION: (30.1) or (10449.1) or (3032.1) or (4645.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#cd383391_6bfb_49a9_9362_f33b81c0bbad
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b6da62ff_398f_4d88_8441_c58621d0882d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf1d578f_8253_4b54_956d_b6e6016a34b4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_26561e6e_5c7f_45a1_8718_cf9ab3fa1a28
constant: false
type: Species
boundary condition: true
initial amount: NaN
is: SBO:0000252
is encoded by: hsa:2348
name: FOLR1
initial concentration: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_74f11926_0218_424d_b668_90aa480cd79b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_524e05ec_6c84_4cfd_85c8_3b5fbe261e6d
value: 1000.0
type: LocalParameter

metaR RE1448R
is version of: http://identifiers.org/ec-code/3.1.3.67
fast: false
modifier: MODEL1109130000#
reactant: MODEL1109130000#
product: MODEL1109130000#
type: Reaction
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7556092
name: RE1448
notes: GENE_ASSOCIATION: 93492.1 SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: 3.1.3.67 Confidence Level: 0 AUTHORS: PMID:7556092,PMID:9367831 NOTES:
is described by: http://identifiers.org/pubmed/9367831
reversible: true

metaM h m
is: SBO:0000247
notes: FORMULA: H CHARGE: 1 HEPATONET_1.0_ABBREVIATION: HC00083 EHMN_ABBREVIATION: C00080 INCHI: InChI=1S/p+1/i/hH
name: proton
is: CHEBI:24636
boundary condition: false
initial amount: NaN
has only substance units: false
constant: false
initial concentration: 1.0
is: C00080
is: http://identifiers.org/pubchem.substance/3380
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_737ab5bc_d408_4d9a_b581_aa31967524c5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_55e020a3_f4bd_4649_b45a_5213f7daee26
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b644f8d_09b4_448c_988f_1bd05bf45de0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_373c472a_8444_4287_9b6d_8040e95d636b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_27c94a7c_fe1a_416f_a260_49ba3661be45
value: 1000.0
type: LocalParameter

metaM h n
has only substance units: false
constant: false
boundary condition: false
type: Species
notes: FORMULA: H CHARGE: 1 INCHI: InChI=1S/p+1/i/hH HEPATONET_1.0_ABBREVIATION: HC00083 EHMN_ABBREVIATION: C00080
is: SBO:0000247
name: proton
is: CHEBI:24636
initial concentration: 1.0
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#caaaecd5_2cb8_4dba_af07_704697572efc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_98e01a39_c57f_4d6e_8829_154c2a139776
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b7ee6da6_30fe_4bba_aae7_f04cced40e9c
constant: true
boundary condition: true
initial amount: NaN
is: SBO:0000252
is encoded by: hsa:64711
has only substance units: false
is: C9JH64
name: HS3ST6
type: Species
initial concentration: NaN

metaM CE0713 m
type: Species
name: 3-oxolinoleoyl-CoA
initial amount: NaN
is: SBO:0000247
initial concentration: 1.0
boundary condition: false
constant: false
has only substance units: false
notes: FORMULA: C39H60N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE0713

http://identifiers.org/biomodels.db/MODEL1109130000#ba06284d_9338_4af4_9b31_764d3360347d
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#ab85c47d_4bc8_42ce_a985_56f7e54102a0
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE3551X
is: SBO:0000176
reversible: true
name: RE3551
is version of: http://identifiers.org/ec-code/1.1.1.1
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: 1.1.1.1 Confidence Level: 0 AUTHORS: PMID:12054595 NOTES:
product: MODEL1109130000#
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/12054595
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_10eabf20_7ad3_4ee5_b8ea_8208cbcbe141
is encoded by: hsa:56922
has only substance units: false
boundary condition: true
is encoded by: hsa:64087
is: SBO:0000297
has part: Q96RQ3
initial amount: NaN
initial concentration: NaN
type: Species
has part: Q9HCC0
constant: true
name: MCCC1:MCCC2

metaR FAOXC18480x
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
is: SBO:0000176
fast: false
is version of: http://identifiers.org/ec-code/4.2.1.74
notes: GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) or (3295.1 and 30.1 and 51.2) SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.74 Confidence Level: 4 AUTHORS: NOTES: _5 rounds of beta ox, 4 degrees loss of saturation -> only 1 fad oxidized to fadh2 - in peroxisome, no fad, 1ste set of beta-ox is by acyl-coa oxidase (passes electrons directly to o2 -> h2o2) peroxisomal (very long chain FA) c18:4,n-6 -> c8:0, 4 step FAO lumped for 2 rounds also includes EC 1.1.1.35, 1.1.1.211, 1.3.3.6, 4.2.1.17, 4.2.1.74 NJ
reversible: false
modifier: MODEL1109130000#
name: Beta oxidation of long chain fatty acid
is version of: ECO:0000269

http://identifiers.org/biomodels.db/MODEL1109130000#fccfffde_68e1_4103_8640_c1b19a045069
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1d9019bb_006c_4c0c_854e_78f333415a73
value: 1000.0
type: LocalParameter

metaM adprib e
has only substance units: false
notes: FORMULA: C15H21N5O14P2 CHARGE: -2 INCHI: InChI=1S/C15H23N5O14P2/c16-12-7-13(18-3-17-12)20(4-19-7)14-10(23)8(21)5(32-14)1-30-35(26,27)34-36(28,29)31-2-6-9(22)11(24)15(25)33-6/h3-6,8-11,14-15,21-25H,1-2H2,(H,26,27)(H,28,29)(H2,16,17,18)/p-2/t5-,6-,8-,9-,10-,11-,14-,15?/m1/s1 EHMN_ABBREVIATION: C00301
is: HMDB01178
type: Species
boundary condition: false
name: D-ribofuranos-5-yl-ADP(2-)
constant: false
is: SBO:0000247
initial concentration: 1.0
initial amount: NaN
is: CHEBI:57967

metaM HC00007 r
has only substance units: false
is: SBO:0000247
constant: false
initial amount: NaN
boundary condition: false
notes: FORMULA: CHARGE: 0 INCHI:
initial concentration: 1.0
name: ApoC2
type: Species

metaR r0770
is described by: http://identifiers.org/pubmed/7567999
reversible: true
is version of: http://identifiers.org/ec-code/2.3.1.85
modifier: MODEL1109130000#
name: (3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase Fatty acid biosynthesis EC:2.3.1.85
is: SBO:0000176
notes: GENE_ASSOCIATION: (1892.1) or (1962.1) or (3030.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
type: Reaction
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false

metaR PROIMINOtc
name: transport of L-Proline by the apical IMINO amino acid transporters in kidney and intestine
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/19657969
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 19657969, PMID: 15632147, PMID: 18195088, PMID: 18400692 EC Number: NOTES: IMINO transporter is suggested to be a candidate for iminoglycinuria (PMID: 16052352). Associted with collectrin in kidney. GENE_ASSOCIATION: (54716.1 and 57393.1)
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/18195088
reversible: false
is described by: http://identifiers.org/pubmed/18400692
is: SBO:0000185
type: Reaction
is described by: http://identifiers.org/pubmed/15632147

metaR 25HVITD3tm
is version of: ECO:0000000
product: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 2 AUTHORS: NOTES: is found in blood --> subsequently has to be transported but how? based on Vitamins, G.F.M. Ball,2004, Blackwell publishing, 1st ed (book) pg.193 IT
is: SBO:0000185
fast: false
name: 25-hydroxyvitamin D3 transport from mitochondria
reversible: false

metaM CE5797 e
constant: false
has only substance units: false
boundary condition: false
type: Species
is: SBO:0000247
name: neuromedin N
initial amount: NaN
notes: FORMULA: C32H51N5O7 CHARGE: 0 INCHI: EHMN_ABBREVIATION: CE5797
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_3bb67b66_20c4_4adf_909e_4642cc34288e
initial concentration: NaN
initial amount: NaN
is: SBO:0000252
type: Species
is: Q92820
boundary condition: true
has only substance units: false
constant: false
name: GGH
notes: DRUGBANK_SUBSTRATE: DB00158, DB00563
is encoded by: hsa:8836

http://identifiers.org/biomodels.db/MODEL1109130000#b2f2defe_5bd3_41c6_b31e_10e715e9f645
value: 0.0
type: LocalParameter

metaR RE3181C
notes: GENE_ASSOCIATION: SUBSYSTEM: Cholesterol metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11111101 NOTES:
reactant: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/11111101
fast: false
is: SBO:0000176
name: RE3181
product: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#fbf5287b_f324_45bd_9f4e_7abbc19ca1a3
value: 0.0
type: LocalParameter

metaR r0757
type: Reaction
is described by: http://identifiers.org/pubmed/17379813
is described by: http://identifiers.org/pubmed/18621017
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 2643.1 SUBSYSTEM: Unassigned EC Number: 1.2.1.5 Confidence Level: 0 AUTHORS: PMID:17379813,PMID:18621017 NOTES:
name: 3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
fast: false
reactant: MODEL1109130000#
reversible: true
product: MODEL1109130000#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.2.1.5

metaM h c
type: Species
is: SBO:0000247
initial amount: NaN
notes: FORMULA: H CHARGE: 1 INCHI: InChI=1S/p+1/i/hH
is: C00080
constant: false
name: proton
is: http://identifiers.org/pubchem.substance/3380
boundary condition: false
is: CHEBI:24636
has only substance units: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_3cd83af6_5eb6_44d3_afea_a36043a7c22a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b436367b_a1e8_41b9_896f_acfab1ef55d3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8120161a_1b8a_4e4d_9d78_ea4512af3265
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8486e5fa_81c5_467b_82e3_7cc856853dd7
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaM CE5343 m
has only substance units: false
initial concentration: 1.0
type: Species
notes: FORMULA: C20H31O4 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5343
initial amount: NaN
boundary condition: false
name: 6,7-dihydro-5-oxo-12-epi-leukotriene B
constant: false
is: SBO:0000247

metaM avite2 r
name: alpha-tocotrienol
type: Species
is: CHEBI:33270
initial amount: NaN
has only substance units: false
is: SBO:0000247
initial concentration: 1.0
is: HMDB06327
boundary condition: false
constant: false
notes: FORMULA: C29H44O2 CHARGE: 0 INCHI: InChI=1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1 EHMN_ABBREVIATION: C14153

http://identifiers.org/biomodels.db/MODEL1109130000#_01fd40ec_4ad0_414d_8a57_7e7155753549
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_fddf5877_dbc6_4f79_8f2c_f0f63686d947
initial amount: NaN
is encoded by: hsa:6557
has only substance units: false
is: E9PDW4
is: SBO:0000252
initial concentration: NaN
constant: false
name: SLC12A1
type: Species
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#d818ae2d_7ecb_4a65_87dc_2230fa861d74
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_73f3a5d3_6137_48b2_8320_de10433ee9ee
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

metaR r0758
notes: GENE_ASSOCIATION: 2643.1 SUBSYSTEM: Tryptophan metabolism EC Number: 1.2.1.3 Confidence Level: 0 AUTHORS: PMID:8155713,PMID:8605195 NOTES:
name: 5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase Tryptophan metabolism EC:1.2.1.3
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.2.1.3
reversible: true
product: MODEL1109130000#
is: SBO:0000176
modifier: MODEL1109130000#
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/8605195
is described by: http://identifiers.org/pubmed/8155713

http://identifiers.org/biomodels.db/MODEL1109130000#da2b30ea_b39e_4f05_92fc_12f6706c1b0b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_89f8988b_bec5_4dfb_b49c_ee75de5331c1
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX ps hs LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: phosphatidylserine (homo sapiens) exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_8549710a_93f2_4f8a_b8d2_7dee36b49432
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_70118d40_9431_45b4_99ab_2ce174ba657d
initial concentration: NaN
initial amount: NaN
name: HS3ST3A1
is encoded by: hsa:9955
type: Species
boundary condition: true
is: SBO:0000252
constant: true
has only substance units: false
is: Q9Y663

http://identifiers.org/biomodels.db/MODEL1109130000#_1f342848_852c_4ca4_bb27_3e0366187a16
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_75945053_00f3_4e69_b80a_a265f2081fbe
value: 1000.0
type: LocalParameter

metaM ha deg1 l
is: SBO:0000247
notes: FORMULA: C22H33N2O16 CHARGE: -1 INCHI:
has only substance units: false
constant: false
initial concentration: 1.0
boundary condition: false
initial amount: NaN
type: Species
name: hyaluronan degradation product 1

metaR r0755
name: 3-Methoxy-4-hydroxyphenylacetaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
is: SBO:0000176
reversible: true
fast: false
type: Reaction
modifier: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (27034.1) or (28976.1) or (37.1) SUBSYSTEM: Unassigned EC Number: 1.2.1.5 Confidence Level: 0 AUTHORS: PMID:1898068 NOTES:
is described by: http://identifiers.org/pubmed/1898068
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.2.1.5

http://identifiers.org/biomodels.db/MODEL1109130000#_0437b32c_8455_4601_bf58_687ba5bfab7f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_060b8e11_a315_4a8d_9909_c28a90763f0f
is encoded by: hsa:113026
name: PLCD3
type: Species
initial amount: NaN
constant: true
is: Q8N3E9
is: SBO:0000252
boundary condition: true
initial concentration: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_39426b78_765e_4970_842b_e3e2b09a23a0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fe3b6fe6_4278_4e30_a27e_ac9fbb1fc120
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6017c575_e96e_4783_ac18_870506340d5f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_40025bd0_6579_43eb_ad82_dd308bd71552
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8632763_a506_457e_ba93_2c5e439790d5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b868fcb2_4a3a_4dc6_80c6_a5ec35eb2271
value: 1000.0
type: LocalParameter

metaR r0756
name: 3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (248.1) or (249.1) or (250.1) or (251.1) SUBSYSTEM: Unassigned EC Number: 1.2.1.5 Confidence Level: 0 AUTHORS: PMID:17379813,PMID:18621017 NOTES:
is described by: http://identifiers.org/pubmed/18621017
fast: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.2.1.5
modifier: MODEL1109130000#
is: SBO:0000176
reversible: true
is described by: http://identifiers.org/pubmed/17379813
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_2e0bcab0_f46c_4a7e_873b_2b16118b0572
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE1448N
product: MODEL1109130000#
name: RE1448
reversible: true
reactant: MODEL1109130000#
is: SBO:0000176
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/7556092
is version of: http://identifiers.org/ec-code/3.1.3.67
is described by: http://identifiers.org/pubmed/9367831
notes: GENE_ASSOCIATION: SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: 3.1.3.67 Confidence Level: 0 AUTHORS: PMID:7556092,PMID:9367831 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_439109d5_7ba6_46ce_b8f0_cf8cde280593
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bb112097_a355_432c_8952_60862b068cab
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_46d4adf2_4779_43f7_ba68_7d9509704b80
value: 0.0
type: LocalParameter

metaM 4h2oglt m
type: Species
is: CHEBI:17742
notes: FORMULA: C5H4O6 CHARGE: -2 INCHI: InChI=1S/C5H6O6/c6-2(4(8)9)1-3(7)5(10)11/h2,6H,1H2,(H,8,9)(H,10,11)/p-2
is: SBO:0000247
has only substance units: false
constant: false
initial amount: NaN
is: HMDB02070
boundary condition: false
initial concentration: 1.0
name: 4-hydroxy-2-oxoglutarate(2-)

metaR C181CRNt
product: MODEL1109130000#
reversible: false
is: SBO:0000185
notes: GENE_ASSOCIATION: 788.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: PMID:14598172 NOTES: TDV
type: Reaction
name: C181 transport into the mitochondria
modifier: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/14598172
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_614a6ec5_5a29_4726_abff_4eaef13c40a7
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_280a913f_562f_4d0f_845e_89ecbd92fb4b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_98d13be9_b116_438c_beff_3f5f9bbe3931
initial concentration: NaN
boundary condition: true
initial amount: NaN
is: SBO:0000252
has only substance units: false
is encoded by: hsa:9962
name: SLC23A2
type: Species
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_58624d52_2154_413f_9e77_f52cd59172de
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b17dcaa4_8f19_4d5a_b59e_e4b4c598be1e
units: dimensionless
value: 0.0
type: LocalParameter

metaM C02528 c
initial concentration: 1.0
type: Species
notes: FORMULA: C24H39O4 CHARGE: -1 INCHI: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00958 EHMN_ABBREVIATION: C02528
name: chenodeoxycholate
initial amount: NaN
is: CHEBI:36234
boundary condition: false
is: HMDB00518
constant: false
is: SBO:0000247
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_53955953_7e91_4fee_8774_47e27aebadb9
is encoded by: hsa:2348
type: Species
has only substance units: false
initial amount: NaN
initial concentration: NaN
is: SBO:0000252
boundary condition: true
constant: false
name: FOLR1

metaR r0753
is: SBO:0000176
reversible: true
modifier: MODEL1109130000#
type: Reaction
fast: false
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Unassigned EC Number: 1.2.1.5 Confidence Level: 0 AUTHORS: PMID:11790142,PMID:12604221 NOTES:
name: 3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11790142
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.2.1.5
is described by: http://identifiers.org/pubmed/12604221

metaM h g
initial amount: NaN
type: Species
initial concentration: 1.0
name: proton
is: SBO:0000247
constant: false
boundary condition: false
has only substance units: false
notes: FORMULA: H CHARGE: 1 INCHI: InChI=1S/p+1/i/hH HEPATONET_1.0_ABBREVIATION: HC00083 EHMN_ABBREVIATION: C00080
is: CHEBI:24636

http://identifiers.org/biomodels.db/MODEL1109130000#e01541e0_18f4_4397_b8ed_e95d9cf13167
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_c03c427d_89dc_475c_b469_fb98d007ff26
has only substance units: false
notes: DRUGBANK_UNKNOWN: DB00583 DRUGBANK_INHIBITOR: DB01074
boundary condition: true
initial amount: NaN
name: CPT2
is encoded by: hsa:1376
type: Species
constant: false
is: SBO:0000252
is: P23786
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_528faecb_bf49_42b2_a348_84c78f0ef35a
is: SBO:0000252
type: Species
boundary condition: true
constant: false
name: SLC22A1
has only substance units: false
initial concentration: NaN
is: O15245
is encoded by: hsa:6580
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_9e5a9bc7_8393_42de_9409_67577beb119e
constant: false
is: Q9BV79
initial concentration: NaN
is: SBO:0000252
boundary condition: true
type: Species
name: MECR
has only substance units: false
initial amount: NaN
is encoded by: hsa:51102

metaM CE5343 r
initial concentration: 1.0
name: 6,7-dihydro-5-oxo-12-epi-leukotriene B
initial amount: NaN
has only substance units: false
is: SBO:0000247
type: Species
boundary condition: false
notes: FORMULA: C20H31O4 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5343
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_8b6f78ab_8ad9_4d61_b1ed_079fbceea028
value: 0.0
type: LocalParameter

metaM CE0782 c
boundary condition: false
notes: FORMULA: C35H54N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE0782
type: Species
is: SBO:0000247
initial amount: NaN
name: 3-oxomyrist-7-enoyl-CoA
has only substance units: false
initial concentration: 1.0
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#f47bbab6_1785_40c2_9518_7c6a6a03bb15
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_42fb0893_0d09_4d71_9eea_97f0f5afac4b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ef60aa72_f62b_4dad_aae3_1005b8f44434
has only substance units: false
boundary condition: true
is: SBO:0000252
constant: false
name: PPA1
is: Q15181
type: Species
initial concentration: NaN
is encoded by: hsa:5464
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_01d52fc5_73c7_48ea_a00b_a246c76e363a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_22857c21_08f6_474a_815a_1cb9d8180055
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a8efc9ab_2f6d_40a2_84c3_92d17082b336
value: 1000.0
type: LocalParameter

metaM CE2424 m
is: SBO:0000247
boundary condition: false
has only substance units: false
name: 3-oxo-cis,cis-5,8-tetradecadienoyl-CoA
type: Species
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C35H52N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE2424
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_d4e30d1a_c755_4f6b_a5f5_34653eade73e
type: Species
is encoded by: hsa:189
initial concentration: NaN
initial amount: NaN
has only substance units: false
notes: DRUGBANK_UNKNOWN: DB00133, DB00145, DB00160, DB02079, DB04083, DB08060 DRUGBANK_COFACTOR: DB00114
is: P21549
name: AGXT
is: SBO:0000252
boundary condition: true
constant: false

metaR RTOT1
is version of: ECO:0000000
reversible: false
name: R total flux
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: R group synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: User defined, tissue specific fluxes that can be customized w/ various ratios of R1 through R5 NJ
type: Reaction
fast: false
product: MODEL1109130000#
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_8275f213_8e1f_42fd_b901_b2c5e3c6d213
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9c4a0012_e9ef_4630_9426_19f7142fea89
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8c8f1f7d_6e64_4e76_a523_63749095b3cc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_47fa8d13_067a_488d_bfab_421544f0cbdc
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0754
is described by: http://identifiers.org/pubmed/17379813
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Unassigned EC Number: 1.2.1.5 Confidence Level: 0 AUTHORS: PMID:17379813,PMID:18621017 NOTES:
modifier: MODEL1109130000#
product: MODEL1109130000#
fast: false
name: 3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
is version of: http://identifiers.org/ec-code/1.2.1.5
is described by: http://identifiers.org/pubmed/18621017
is: SBO:0000176
reversible: true
type: Reaction

metaM apoC Lys m
notes: FORMULA: C6H13N2OX CHARGE: 0 INCHI:
initial concentration: 1.0
boundary condition: false
name: Apocarboxylase (Lys residue)
type: Species
initial amount: NaN
has only substance units: false
is: SBO:0000247
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_979d47a4_2f96_4180_9ca4_499179410732
value: 0.0
type: LocalParameter

metaM bilglcur c
name: mono(glucosyluronic acid)bilirubin(2-)
is: CHEBI:57767
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C39H44N4O12 CHARGE: 0 INCHI: InChI=1S/C39H44N4O12/c1-7-20-19(6)36(50)43-27(20)14-25-18(5)23(10-12-31(46)54-39-34(49)32(47)33(48)35(55-39)38(52)53)29(41-25)15-28-22(9-11-30(44)45)17(4)24(40-28)13-26-16(3)21(8-2)37(51)42-26/h7-8,13-14,32-35,39-41,47-49H,1-2,9-12,15H2,3-6H3,(H,42,51)(H,43,50)(H,44,45)(H,52,53)/b26-13+,27-14+/t32-,33-,34+,35-,39+/m0/s1 EHMN_ABBREVIATION: C03374
is: SBO:0000247
initial amount: NaN
type: Species
has only substance units: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_797f72df_9abb_44f4_9d1a_2d301354e41b
value: 0.0
type: LocalParameter

metaM HC10854 c
name: palmitoleoyl-Carnitine
is: SBO:0000247
constant: false
notes: FORMULA: CHARGE: 0 INCHI:
has only substance units: false
boundary condition: false
initial amount: NaN
type: Species
initial concentration: 1.0

metaM quln c
initial concentration: 1.0
constant: false
boundary condition: false
name: quinolinate(2-)
is: HMDB00232
is: CHEBI:29959
has only substance units: false
is: SBO:0000247
type: Species
notes: FORMULA: C7H3NO4 CHARGE: -2 INCHI: InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)/p-2 HEPATONET_1.0_ABBREVIATION: HC01168 EHMN_ABBREVIATION: C03722
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_22831354_b82e_469a_938b_b8b6539d1c5f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e893c9b2_6f88_4d8a_b772_78da0c75c8bd
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a4f1252_84ec_44af_a516_d28cce83c5ce
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d33a7c12_2b7e_4603_b9ab_eb6a5abedde5
value: 0.0
type: LocalParameter

metaR RTOT2
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: R group synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: User defined, tissue specific fluxes that can be customized w/ various ratios of R1 through R5 NJ
is: SBO:0000176
reactant: MODEL1109130000#
name: R total flux
is version of: ECO:0000000
reversible: false
type: Reaction
fast: false

metaR EX thymd LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Thymidine exchange
type: Reaction

metaM h e
boundary condition: false
has only substance units: false
initial amount: NaN
initial concentration: 1.0
is: C00080
is: SBO:0000247
constant: false
is: http://identifiers.org/pubchem.substance/3380
is: CHEBI:24636
notes: FORMULA: H CHARGE: 1 INCHI: InChI=1S/p+1/i/hH
type: Species
name: proton

http://identifiers.org/biomodels.db/MODEL1109130000#_4def5fc6_e08c_4538_b0f1_7f908fa75452
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5525 m
has only substance units: false
constant: false
boundary condition: false
initial concentration: 1.0
name: 12-oxo-20-carboxy-leukotriene B4
notes: FORMULA: C20H26O6 CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE5525
type: Species
initial amount: NaN
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_902eb688_3d50_4cd4_8379_b411e81d30a5
value: 1000.0
type: LocalParameter

metaR r0752
is described by: http://identifiers.org/pubmed/10424772
type: Reaction
name: 3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5
modifier: MODEL1109130000#
reversible: true
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.2.1.5
notes: GENE_ASSOCIATION: (30.1) or (10449.1) or (3032.1) or (4645.1) SUBSYSTEM: Unassigned EC Number: 1.2.1.5 Confidence Level: 0 AUTHORS: PMID:10424772,PMID:11958479,PMID:3466164 NOTES:
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/3466164
fast: false
is described by: http://identifiers.org/pubmed/11958479

http://identifiers.org/biomodels.db/MODEL1109130000#_d8d09990_ba8b_42cd_a383_4404f9ccc008
boundary condition: true
constant: false
has only substance units: false
initial amount: NaN
type: Species
initial concentration: NaN
name: FLAD1
is: SBO:0000252
is encoded by: hsa:80308

http://identifiers.org/biomodels.db/MODEL1109130000#_484dd35a_6d13_4e25_ac1a_5cd8d3163c17
units: dimensionless
value: 0.0
type: LocalParameter

metaR RTOT3
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: R group synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: User defined, tissue specific fluxes that can be customized w/ various ratios of R1 through R5 NJ
is: SBO:0000176
reactant: MODEL1109130000#
name: R total flux
type: Reaction
is version of: ECO:0000000
product: MODEL1109130000#
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_1c737783_d841_4306_a56f_6b1ac4126532
type: Species
boundary condition: true
name: CYP4F3:CYP4F2
has part: P78329
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:4051
is: SBO:0000297
has part: Q08477
is encoded by: hsa:8529
constant: true
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#d543d00b_b079_4352_af06_6db1f28f391d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_aa521881_f2f0_4ca2_a460_583e7073b1fa
has only substance units: false
constant: false
name: FOLR1
type: Species
is encoded by: hsa:2348
boundary condition: true
initial amount: NaN
initial concentration: NaN
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_98a0ccd0_c574_44a0_94df_a10454e515b3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bfb9e8f4_5121_4c05_b32a_14f90cad2017
value: 1000.0
type: LocalParameter

metaM c101crn c
notes: FORMULA: C17H31NO4 CHARGE: 0
type: Species
initial amount: NaN
constant: false
has only substance units: false
name: decenoyl carnitine
is: HMDB13205
initial concentration: 1.0
is: SBO:0000247
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_21ed7bb3_6bf0_4348_9d73_ca9ee9db5adc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_66dd4d86_d553_4bf4_b035_f34dffab363f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed2391ba_e924_459f_861b_c72c9bc0522a
units: dimensionless
value: 0.0
type: LocalParameter

metaM pd3 c
initial concentration: 1.0
initial amount: NaN
is: HMDB06500
notes: FORMULA: C27H44O CHARGE: 0 INCHI: InChI=1/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h10,12-13,19,21,24-26,28H,6-9,11,14-18H2,1-5H3/b13-12-/t21-,24+,25-,26?,27-/m1/s1
constant: false
boundary condition: false
is: SBO:0000247
type: Species
has only substance units: false
name: Previtamin D3

metaR EX imp LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: IMP exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_7fcbf4c6_3739_438f_8df5_80b1abc8f3ae
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d87d6aff_b597_4464_a810_c2538e9c053c
initial concentration: NaN
is encoded by: hsa:93034
is: SBO:0000252
initial amount: NaN
name: NT5C1B
has only substance units: false
is: B4DZ86
boundary condition: true
type: Species
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#f6ad4bcf_6f56_4bda_af06_2560cc8a50b8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a983e8c1_010d_4241_bd1e_ebd589ca76bc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8ac2dc50_9c25_4740_b692_5cd2ad6ea54d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_44ce3df9_8943_4d46_a8df_f8e9e7f4c3f3
initial amount: NaN
initial concentration: NaN
boundary condition: true
constant: false
is: SBO:0000252
type: Species
is encoded by: hsa:117247
is: Q8TF71
name: SLC16A10
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_895b1eb3_1fcb_42a3_917f_a7db073246d8
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0d5ecaf0_56a2_43a5_ae02_913485bbc605
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e472e9ad_cf09_4f01_8200_c407832c4d8e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_203f8e98_43a1_40f0_b4ae_2690d2be0fa2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ddcf446e_e292_4cb5_8dc4_e01e7da7d7f8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a1d4324a_b835_472b_8e16_596a8ca2b64a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f8e25fbd_50ba_428f_bc89_10b6129ccc3c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_44769286_65ff_40a7_b040_f15013b7eee0
has only substance units: false
is encoded by: hsa:54
name: ACP5
is: P13686
type: Species
constant: false
initial amount: NaN
initial concentration: NaN
boundary condition: true
is: SBO:0000252

metaM c101crn e
boundary condition: false
initial amount: NaN
type: Species
notes: FORMULA: C17H31NO4 CHARGE: 0
constant: false
is: HMDB13205
name: decenoyl carnitine
is: SBO:0000247
has only substance units: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_90600712_c9df_48ec_80a7_6b46dc66db1d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a851c163_8c74_43af_bf21_c4b936217aa1
value: 1000.0
type: LocalParameter

metaR EICOSTETt
is: SBO:0000185
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11788354
fast: false
is described by: http://identifiers.org/pubmed/12864740
name: fatty acid transport via diffusion
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:11788354,PMID:12864740 NOTES: NJ
is version of: ECO:0000000
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_0936802a_3617_4618_954f_7100df2fb897
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fd645276_a005_4532_ad79_af4dc9c99d9c
value: 1000.0
type: LocalParameter

metaM CE5343 x
boundary condition: false
is: SBO:0000247
notes: FORMULA: C20H31O4 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5343
initial amount: NaN
has only substance units: false
constant: false
initial concentration: 1.0
name: 6,7-dihydro-5-oxo-12-epi-leukotriene B
type: Species

metaM CE2424 x
notes: FORMULA: C35H52N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE2424
has only substance units: false
boundary condition: false
is: SBO:0000247
constant: false
name: 3-oxo-cis,cis-5,8-tetradecadienoyl-CoA
type: Species
initial concentration: 1.0
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#db98d210_9938_4a11_8d99_9ace4bc28f03
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_71bb47dd_d1ef_44b0_8007_3c77cdf581d7
value: 0.0
type: LocalParameter

metaM C02528 e
is: CHEBI:36234
has only substance units: false
constant: false
notes: FORMULA: C24H39O4 CHARGE: -1 INCHI: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00958 EHMN_ABBREVIATION: C02528
boundary condition: false
type: Species
is: SBO:0000247
is: HMDB00518
initial concentration: 1.0
name: chenodeoxycholate
initial amount: NaN

metaM c6dc e
type: Species
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C13H22NO6 CHARGE: -1
is: SBO:0000247
has only substance units: false
constant: false
initial amount: NaN
name: adipoyl carnitine

http://identifiers.org/biomodels.db/MODEL1109130000#_825b432d_9b27_40c7_a964_aad5d5b330df
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7139ddb9_6d86_4475_b76a_4540c5f2d7f9
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7c074213_a190_4d90_a68a_c3f6fb411f0c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_90dc6e11_7ae0_4fbd_b04f_3c77c33d2627
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V1C1:ATP6V1E1:ATP6V1G2:ATP6V1F
type: Species

metaM apoC Lys c
initial amount: NaN
type: Species
initial concentration: 1.0
constant: false
is: SBO:0000247
name: Apocarboxylase (Lys residue)
notes: FORMULA: C6H13N2OX CHARGE: 0 INCHI:
boundary condition: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#b121e513_e23a_487f_b767_199f4756e481
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eb9a82d3_2bfb_4fc8_a1bf_c6f89b52ff15
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e60eacbb_c83d_4fbe_80bc_d0c43aa8813e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a6d61f8f_d0d7_41c6_b6c0_9450599fac8d
is: SBO:0000252
has only substance units: false
initial concentration: NaN
type: Species
name: PDE9A
boundary condition: true
initial amount: NaN
is encoded by: hsa:5152
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_1b784a23_2084_4eb8_b0cc_8dea9d85731c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6050188e_1ddc_4f3d_8cb1_7521877b38cf
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_641f55c6_dcf6_4254_82e1_532b8f5836bf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_38e413f0_4281_49ef_88f1_873017015798
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_23085f19_85f6_497f_83ab_1e8a38633d02
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b5ac105b_c81d_4c69_9f9a_1c3828d05377
value: 1000.0
type: LocalParameter

metaM c6dc c
initial amount: NaN
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C13H22NO6 CHARGE: -1
has only substance units: false
is: SBO:0000247
type: Species
constant: false
name: adipoyl carnitine

http://identifiers.org/biomodels.db/MODEL1109130000#_3e26d8dd_1650_415e_9ba2_9c43abea69a1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5be78849_c29b_4650_a8da_1da2c3dc114d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b540b58_6a43_41f5_b92b_c72db17d8e9a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a2c7d45a_9845_45fc_bd82_2d1c3fb1b976
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6fe97373_5edf_42f1_a850_45e70e53747c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0f6a9ba5_8c35_4db3_8d39_fcf98497ef4e
value: 0.0
type: LocalParameter

metaR LINKDEG2ly
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Chondroitin sulfate degradation EC Number: Confidence Level: 2 AUTHORS: PMID:8993162 NOTES: NCD
is described by: http://identifiers.org/pubmed/8993162
name: degradation of proteoglycan linkage region, lysosomal
is: SBO:0000176
reversible: false
fast: false
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_b16b7c87_dc0a_4707_a499_febcd467d1ae
boundary condition: true
type: Species
is encoded by: hsa:4668
initial amount: NaN
initial concentration: NaN
name: NAGA
is: P17050
constant: false
has only substance units: false
is: SBO:0000252

metaR EX mercplaccys LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: 3-mercaptolactate-cysteine disulfide exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#fd5c0817_fce8_4228_b867_913ee02a8c84
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_20190877_f443_48ea_b0d3_84b45b9e0795
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a6fb8838_ba36_4253_843e_98902bcc864a
units: dimensionless
value: 0.0
type: LocalParameter

metaM mn c
constant: false
type: Species
name: beta-1,4-mannose-N-acetylglucosamine
notes: FORMULA: C14H25NO11 CHARGE: 0 INCHI: InChI=1/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8-,9-,10+,11+,12-,13-,14-/m1/s1
has only substance units: false
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247
boundary condition: false
is: HMDB06535

http://identifiers.org/biomodels.db/MODEL1109130000#b9390714_5e4e_4ef8_98f8_a6c8bcd122e6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5acb95c4_b22b_4530_a757_6afa7d6d4798
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE0782 m
is: SBO:0000247
has only substance units: false
initial amount: NaN
type: Species
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C35H54N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE0782
name: 3-oxomyrist-7-enoyl-CoA
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4cfad4bc_f945_4336_add7_0f509eff4c87
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a911d77_bda0_469b_ae2e_16a5a59af776
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e4fd2e74_7c3d_491b_901a_f47fab8758fc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8eecef03_f864_462a_b1b4_f5f782be2872
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_105d4d81_01f3_45da_bcc5_082a8b30be65
value: 1000.0
type: LocalParameter

metaR TETHEX3COAtx
name: fatty acid intracellular transport
is: SBO:0000185
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 2 AUTHORS: NOTES: interaction between peroxisomes and ER (some enzymes on the outer membrane) NJ
is version of: ECO:0000000
product: MODEL1109130000#
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#c2cac730_d894_4cb6_a51f_d785f59a0580
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ffb8be56_8ab9_4150_a137_3ad5f3555f24
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0bd3f149_d812_4fa7_a109_5ad0b5765768
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_45f6dbf1_f115_421d_a874_b40bf44ad7d1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_68e9d517_04a8_4e45_94da_67c24a41270f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6344f2a0_28ab_42da_a538_3abbe44addd6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a1b5e4d_1616_4a9a_9c88_dd61e0b8f73f
name: SLC25A2
boundary condition: true
has only substance units: false
initial amount: NaN
type: Species
is encoded by: hsa:83884
initial concentration: NaN
is: SBO:0000252
constant: false
is: Q9BXI2

http://identifiers.org/biomodels.db/MODEL1109130000#a3da1fa9_2cba_41c9_80ff_b3f68baea17c
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE2155C
reactant: MODEL1109130000#
product: MODEL1109130000#
name: RE2155
notes: GENE_ASSOCIATION: SUBSYSTEM: Miscellaneous EC Number: 1.14.99.10 Confidence Level: 0 AUTHORS: PMID:12376740 NOTES:
reversible: false
type: Reaction
is version of: http://identifiers.org/ec-code/1.14.99.10
fast: false
is described by: http://identifiers.org/pubmed/12376740
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_64b2890a_a729_413f_bb2c_69f1f0158e9d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_02a21fa8_9f20_45c1_8379_df04fc610b07
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dff4f0bc_5de9_492a_a7e7_c972ed1aba9d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_48f09a29_d246_48ef_8573_44f932c6c775
value: 0.0
type: LocalParameter

metaR ALDD2xm
type: Reaction
is described by: http://identifiers.org/pubmed/19382905
is version of: ECO:0000134
is described by: http://identifiers.org/pubmed/18983993
reversible: false
is: SBO:0000176
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.2.1.3
is described by: http://identifiers.org/pubmed/18983992
name: aldehyde dehydrogenase (acetylaldehyde, NAD), mitochondrial
fast: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (219.1) or (217.1) SUBSYSTEM: Glycolysis/gluconeogenesis EC Number: 1.2.1.3 Confidence Level: 0 AUTHORS: PMID:18983992,PMID:18983993,PMID:19382904,PMID:19382905 NOTES: NCD. For NAD
is described by: http://identifiers.org/pubmed/19382904
reactant: MODEL1109130000#

metaM 3hbcoa R c
type: Species
notes: FORMULA: C25H38N7O18P3S CHARGE: -4 INCHI: InChI=1S/C25H42N7O18P3S/c1-13(33)8-16(35)54-7-6-27-15(34)4-5-28-23(38)20(37)25(2,3)10-47-53(44,45)50-52(42,43)46-9-14-19(49-51(39,40)41)18(36)24(48-14)32-12-31-17-21(26)29-11-30-22(17)32/h11-14,18-20,24,33,36-37H,4-10H2,1-3H3,(H,27,34)(H,28,38)(H,42,43)(H,44,45)(H2,26,29,30)(H2,39,40,41)/p-4/t13-,14-,18-,19-,20+,24-/m1/s1
initial concentration: 1.0
has only substance units: false
is: SBO:0000247
initial amount: NaN
is: HMDB01166
constant: false
name: (R)-3-hydroxybutanoyl-CoA(4-)
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_78ace2bd_7b38_4b8b_a6fc_59ce6e5e8ca2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf4a1b4b_3cec_42c2_ba21_337921afb808
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d21732b8_b571_4ae6_9106_b07c7af01ec8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_320623da_7b5b_4c9b_8751_d53ca7e3accc
value: 0.0
type: LocalParameter

metaM CE5114 r
name: trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA
type: Species
initial amount: NaN
notes: FORMULA: C41H62N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5114
has only substance units: false
is: SBO:0000247
constant: false
initial concentration: 1.0
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_0cb8a7a5_3bc6_4e30_aacd_8accb6765973
is: B4DSP5
initial concentration: NaN
initial amount: NaN
is: SBO:0000252
constant: true
name: B4GALNT1
type: Species
is encoded by: hsa:2583
has only substance units: false
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_60f45e8a_b546_47a6_96ee_a4e4dd2ee93e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_48c61f31_da75_499b_b9df_97199d94ddd4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_98f53ff9_9c8b_4327_8af5_0a5756455ea0
value: 0.0
type: LocalParameter

metaM glc D r
boundary condition: false
is: SBO:0000247
is: CHEBI:4167
constant: false
type: Species
notes: FORMULA: C6H12O6 CHARGE: 0 INCHI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00040
has only substance units: false
name: D-glucose
initial concentration: 1.0
initial amount: NaN
is: HMDB00122

http://identifiers.org/biomodels.db/MODEL1109130000#_7278f84f_a899_4da8_a70e_d1779baea4be
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d8d3c3a9_6b90_4301_85ef_8bfa2e8f8cf3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_536377a2_297f_4a12_884d_16d24f7f2fed
value: 0.0
type: LocalParameter

metaR MANt1r
is described by: http://identifiers.org/pubmed/1701966
is described by: http://identifiers.org/pubmed/2182619
type: Reaction
is described by: http://identifiers.org/pubmed/7926364
is described by: http://identifiers.org/pubmed/12750891
is described by: http://identifiers.org/pubmed/11882499
fast: false
is: SBO:0000185
is described by: http://identifiers.org/pubmed/9770484
notes: GENE_ASSOCIATION: (6513.1) or (6515.1) or (6514.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:11882499,PMID:12135767,PMID:12750891,PMID:1701966,PMID:2182619,PMID:3103217,PMID:3399500,PMID:3839598,PMID:7926364,PMID:9770484 NOTES: NCD
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3839598
is described by: http://identifiers.org/pubmed/3103217
is described by: http://identifiers.org/pubmed/12135767
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3399500
reactant: MODEL1109130000#
is version of: ECO:0000269
reversible: true
name: mannose transport (uniport)

http://identifiers.org/biomodels.db/MODEL1109130000#e5ba174a_2fed_4657_b1e9_78442eac2fe8
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_979d1888_93cd_4a9c_a859_7d9e04763622
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ec3b0b0a_7fa4_46d6_968b_e6dfb8074ab1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b77edec_b006_4ee8_a380_921e9781ee29
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b01b6e8e_1d55_4613_bb5e_a85f9f9a59db
has only substance units: false
name: BCKDHB
initial concentration: NaN
is: P21953
is encoded by: hsa:594
initial amount: NaN
is: SBO:0000252
constant: false
type: Species
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_3a1d682f_51d1_4c13_a8d3_e2278785f48d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_75713c1c_50ab_46c4_9d2d_e070e94f1f0f
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_dbe29cf5_c75f_4f07_b80c_b28e9c2eed09
has only substance units: false
is encoded by: hsa:1558
name: CYP2C8
initial amount: NaN
type: Species
initial concentration: NaN
boundary condition: true
is: B7Z1F5
constant: false
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_178041cc_3010_491a_85a7_c5de11438678
has only substance units: false
is: SBO:0000252
name: GMDS
initial concentration: NaN
type: Species
boundary condition: true
initial amount: NaN
is: O60547
constant: false
is encoded by: hsa:2762

metaM CE5525 c
has only substance units: false
is: SBO:0000247
constant: false
initial amount: NaN
boundary condition: false
type: Species
name: 12-oxo-20-carboxy-leukotriene B4
initial concentration: 1.0
notes: FORMULA: C20H26O6 CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE5525

http://identifiers.org/biomodels.db/MODEL1109130000#_8078a515_78d7_4c77_bfaf_16be149b597a
units: dimensionless
value: 0.0
type: LocalParameter

metaR EPCTX
type: Reaction
reactant: MODEL1109130000#
product: MODEL1109130000#
is version of: ECO:0000269
name: ethanolamine-phosphate cytidylyltransferase
is: SBO:0000176
modifier: MODEL1109130000#
reversible: false
is version of: http://identifiers.org/ec-code/2.7.7.14
fast: false
notes: GENE_ASSOCIATION: 5833.1 SUBSYSTEM: Glycerophospholipid metabolism EC Number: 2.7.7.14 Confidence Level: 4 AUTHORS: NOTES: SAB

http://identifiers.org/biomodels.db/MODEL1109130000#a7a4aae1_093a_4061_b0e9_4045884c3198
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4764b884_8fd9_4aaf_b9e2_6f652857efe9
value: 0.0
type: LocalParameter

metaM CE4805 x
constant: false
notes: FORMULA: C32H52N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE4805
is: SBO:0000247
type: Species
has only substance units: false
boundary condition: false
initial amount: NaN
initial concentration: 1.0
name: 4(R),8-dimethyl-nonanoyl-CoA

http://identifiers.org/biomodels.db/MODEL1109130000#_18efe029_1791_462c_b734_f28ffdeddb9e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6930b832_dda7_436a_8e71_6ed7d7e16a8c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d2bcc11c_a9fc_4992_87e6_ff1598c9c8c8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_68c9c709_d7d1_4dab_bf9f_6796390d81a5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_46caa9ea_905f_45aa_9d3e_e0b310e9c5d0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_12711bf2_40f8_4a73_b1af_44c6345a2b8d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2ac5bcad_1d73_4f08_9831_ca8ee23257c6
type: Species
is encoded by: hsa:1788
has only substance units: false
name: DNMT3A
initial concentration: NaN
is: SBO:0000252
boundary condition: true
initial amount: NaN
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_4d7c24b5_4bc3_4319_9658_8ee9e482db42
value: 0.0
type: LocalParameter

metaR LEUKTRF4t
is version of: ECO:0000000
type: Reaction
reactant: MODEL1109130000#
name: leukotriene F4 transport
fast: false
is: SBO:0000185
reversible: true
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_7ee4764d_6f03_4803_8233_93a26750faa1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9338f041_4caa_40ae_80db_a36fcff9f430
type: Species
initial concentration: NaN
boundary condition: true
name: COQ6
is: B7Z3K8
is: SBO:0000252
is encoded by: hsa:51004
constant: false
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#f1874937_75a7_4a5f_b100_e9e72f2d4f29
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#de3d240f_ae33_4858_8d3f_e2be210bab07
value: 1000.0
type: LocalParameter

metaR RE2334C
type: Reaction
name: RE2334
is described by: http://identifiers.org/pubmed/10047787
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Urea cycle EC Number: Confidence Level: 0 AUTHORS: PMID:10047787,PMID:7040832 NOTES:
is described by: http://identifiers.org/pubmed/7040832
reversible: true
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_88ad3f8f_fd28_4ad9_aedf_a8b9bdffe4bb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#df924918_e6fe_41b8_a8ce_1058ed3e98d7
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c9ed0a66_9f82_4fa6_b13c_3f9b534dccdb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_297c3d89_ee7c_4582_8e23_c6c6e9e12d9c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1fc0ba30_3ecc_44c7_8050_8e11ea3f91bb
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c3b831f0_1433_42d4_b368_4f284e40208a
value: 0.0
type: LocalParameter

metaM CE5114 x
has only substance units: false
notes: FORMULA: C41H62N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5114
initial amount: NaN
initial concentration: 1.0
constant: false
is: SBO:0000247
name: trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA
type: Species
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4cfb7f8e_3c69_4972_a46f_d64d402b840d
value: 0.0
type: LocalParameter

metaM mn l
type: Species
boundary condition: false
name: beta-1,4-mannose-N-acetylglucosamine
initial amount: NaN
has only substance units: false
is: HMDB06535
notes: FORMULA: C14H25NO11 CHARGE: 0 INCHI: InChI=1/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8-,9-,10+,11+,12-,13-,14-/m1/s1
initial concentration: 1.0
is: SBO:0000247
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_95431598_498b_46cb_a6db_e8a9a6fb2084
units: dimensionless
value: 0.0
type: LocalParameter

metaM avite2 e
is: CHEBI:33270
initial amount: NaN
name: alpha-tocotrienol
is: HMDB06327
is: SBO:0000247
initial concentration: 1.0
notes: FORMULA: C29H44O2 CHARGE: 0 INCHI: InChI=1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1 EHMN_ABBREVIATION: C14153
boundary condition: false
has only substance units: false
constant: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_9aa1b4a6_6f5a_4970_9bee_979b9888345d
is encoded by: hsa:411
has only substance units: false
initial concentration: NaN
constant: true
type: Species
initial amount: NaN
name: ARSB
is: A8K4A0
is: SBO:0000252
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#a4c76dc4_d3cf_46a3_ac2f_16706bbbc85f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0fab85cd_6d85_4173_a797_d78fcc8100dc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cf8ed82d_9ff3_4ef9_a1b2_fbb43691f07d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2db16615_3d1f_4d45_85a9_349786cde6c0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1d2b7f5a_4c3c_480b_a447_11f99c2d80e3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dffb64a8_4482_4e3d_b03b_754aa11d919d
units: dimensionless
value: 0.0
type: LocalParameter

metaM 4abut l
boundary condition: false
is: SBO:0000247
has only substance units: false
constant: false
initial amount: NaN
notes: FORMULA: C4H9NO2 CHARGE: 0 INCHI: InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) HEPATONET_1.0_ABBREVIATION: HC00284 EHMN_ABBREVIATION: C00334
is: HMDB00112
name: gamma-aminobutyric acid
initial concentration: 1.0
is: CHEBI:16865
type: Species

metaR PNTOte
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000185
fast: false
reversible: true
name: Transport of (R)-Pantothenate
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_150c6d10_bd11_4b89_8d10_bd85efabd6fa
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_49adabc4_2822_484b_a7bf_80e170ccb171
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9328cd4a_9b82_4b28_8a0c_8966ace74659
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_20883fd0_5858_4ea7_8ef8_bc54cc3b293f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fdfbb4b3_72d8_41f7_997d_a00862dc0b24
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1255254b_abac_4163_8736_edd6b3c1616f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_092905d3_168e_4444_9f7c_68555a41c436
value: -1000.0
type: LocalParameter

metaM chito2pdol L c
initial concentration: 1.0
name: N,N-Diacetylchitobiosyldiphosphodolichol, human liver homolog
is: CHEBI:12427
notes: FORMULA: C1240H2028N20O170P20 CHARGE: -20 INCHI:
has only substance units: false
type: Species
constant: false
initial amount: NaN
is: SBO:0000247
is: HMDB01196
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#e1317456_55d2_4f17_b9c7_a1ffe48978b2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aaad1047_77f5_43eb_bf27_302282bf4a70
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3c765375_cc22_4caf_9df6_57d51d68bb5e
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#b23fc75d_eb40_4d8f_8add_1df10372ee42
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4a5d97a0_da9a_41b0_a345_4e557299e065
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a5e9ed89_ee1f_4f65_8a84_8112e7907a85
value: 0.0
type: LocalParameter

metaM 4abut m
is: HMDB00112
is: SBO:0000247
type: Species
constant: false
initial amount: NaN
notes: FORMULA: C4H9NO2 CHARGE: 0 HEPATONET_1.0_ABBREVIATION: HC00284 EHMN_ABBREVIATION: C00334 INCHI: InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
is: C00334
is: CHEBI:16865
has only substance units: false
initial concentration: 1.0
name: 4-Aminobutanoate
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#c9e35ae6_702d_41d8_b578_d042375c7b20
units: dimensionless
value: 0.0
type: LocalParameter

metaR ASCBSVCTtc
name: transport of L-Ascorbate by SVCT1 or SVCT2 transporter
is described by: http://identifiers.org/pubmed/18094143
reversible: false
is described by: http://identifiers.org/pubmed/17222174
is: SBO:0000185
reactant: MODEL1109130000#
type: Reaction
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 18094143, PMID: 11396616, G.F.M. Ball (2006) Vitamins their role in the human body, Blackwell publishing, chapter 19, page 395-398, PMID: 17222174 EC Number: NOTES: SVCT1 and SVCT2 differ in their tissue distribution, SVCT1 is more ubiquitously expressed, where as SVCT1 is confined to intestine, liver and kidney. The Na+ symport transport is energized by Na+/K+ ATPase, therefore its a secondary active transport ( G.F.M. Ball (2006) Vitamins their role in the human body, Blackwell publishing, chapter 19, page 395-398). Vitamin C is absorbed only in ascorbate form, can be oxidized into dehydroascorbate, and can then enter the blood stream (Sareen S. Gropper, Jack L. Smith, James L. Groff (2009) Advanced nutrition and human metabolism, Wadsworth cengage learning, 5th edition, page 312-313). GENE_ASSOCIATION: (9963.1 or 9962.1)
is described by: http://identifiers.org/pubmed/11396616
fast: false
modifier: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_654c4ece_4a2f_4320_a55a_026a3becff8f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1c6f1433_bf54_4603_9185_5f268ce77f15
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e5dcf7d1_6c31_44c7_8dfa_848af72b475c
value: 0.0
type: LocalParameter

metaM avite2 c
name: alpha-tocotrienol
is: SBO:0000247
initial amount: NaN
notes: FORMULA: C29H44O2 CHARGE: 0 INCHI: InChI=1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1 EHMN_ABBREVIATION: C14153
is: HMDB06327
constant: false
initial concentration: 1.0
type: Species
is: CHEBI:33270
has only substance units: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6f2457ea_a989_435a_8e23_ca032c9b2a9e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4f44781d_e189_425f_8f91_397cae88e051
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX s2l2n2m2masn LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: de-Fuc form of PA6 exchange
type: Reaction

metaM 4abut n
notes: FORMULA: C4H9NO2 CHARGE: 0
boundary condition: false
has only substance units: false
is: HMDB00112
is: C00334
initial concentration: 1.0
name: 4-Aminobutanoate
is: SBO:0000247
type: Species
constant: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_8a1aea22_90a1_40d5_a950_d54ed0dd444b
value: 0.0
type: LocalParameter

metaM glc D l
initial amount: NaN
is: HMDB00122
is: SBO:0000247
boundary condition: false
is: CHEBI:4167
notes: FORMULA: C6H12O6 CHARGE: 0 INCHI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00040
type: Species
initial concentration: 1.0
constant: false
name: D-glucose
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_0e4718b3_22b5_49d9_abed_ea5bd213858e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9e0f0bd1_c902_430b_ab36_422b8a2e7e3c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9d4aef68_822f_485d_8f75_331ce9eeca2a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a90463e9_d9a7_4079_850f_20703b53707a
is: Q5JPH6
initial amount: NaN
initial concentration: NaN
is encoded by: hsa:124454
name: EARS2
constant: true
has only substance units: false
boundary condition: true
type: Species
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_9d34e40a_a409_4625_adf5_565786214502
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0363f404_d22c_4405_b775_dc472b4916fa
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_07dd4a04_4f19_48c4_972c_87ba1d0531a3
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC01446 e
constant: false
is: SBO:0000247
name: 3-Ketolactose
type: Species
notes: FORMULA: CHARGE: 0 EHMN_ABBREVIATION: C05403
is: http://identifiers.org/pubchem.substance/7770
initial amount: NaN
is: C05403
boundary condition: false
initial concentration: 1.0
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_363f1077_8e6a_487f_9dc8_03558edf8059
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b640484b_9fef_4ea8_a697_6509f4db59d6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_65a3eda0_938c_424b_b391_3d9147617dcc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_57fb289f_361d_4267_909f_8a2e0327a3e4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d671652e_e8ab_4941_85a4_b03769c009ea
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b8d1dc6c_d3b6_43ea_bbc9_c1643e8ad949
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_964885c1_afa7_46e8_8d68_e152449e47ec
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_80a6bacc_dbd3_4cc2_919e_d3aa09716278
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_86789852_c688_45c7_a9c1_ac10203574b7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b9176f32_15ee_4ffb_8e41_f3884c5eb7f8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_23a1577f_d272_421b_8de0_53739bd2b66c
value: 0.0
type: LocalParameter

metaR r0762
is described by: http://identifiers.org/pubmed/7567999
is: SBO:0000176
name: (3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase Fatty acid biosynthesis EC:2.3.1.85
type: Reaction
fast: false
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.85
notes: GENE_ASSOCIATION: (AA177072.1) or (2194.1) or (54995.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
product: MODEL1109130000#
reversible: true
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#eab392bd_fae4_4d5d_b2de_9e5e82fcc05a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_61f006cd_b17d_46af_af02_f6542a28f493
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_966a7c94_7433_47c4_958c_5e98fce4cb20
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33f16163_f77b_44be_a323_096af5d786a3
boundary condition: true
is: Q5VSR7
is encoded by: hsa:5214
has only substance units: false
initial amount: NaN
initial concentration: NaN
is: SBO:0000252
type: Species
name: PFKP
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#fa16a170_fd7e_4eae_bc74_55a477016f53
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_189c247a_4009_4a8e_a160_d5bcb6bf85f3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b4c0c81_2411_4605_8cc6_f7d6fcb28f78
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31d29fa8_e9b7_42d9_a9a8_5fbf2e1bfd9b
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0761
is described by: http://identifiers.org/pubmed/7567999
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7834997
type: Reaction
is described by: http://identifiers.org/pubmed/4452359
product: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8962082
name: (3R)-3-Hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11750882
is described by: http://identifiers.org/pubmed/6137188

http://identifiers.org/biomodels.db/MODEL1109130000#_78f2b458_322c_4455_89f4_b4f35f5c5271
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_50a82e9e_aa7d_4956_8ac4_ee0d0bdbd3c6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5512f1a7_36a5_4189_a846_b70a82447ae1
value: 0.0
type: LocalParameter

metaM glc D g
is: HMDB00122
initial amount: NaN
is: CHEBI:4167
has only substance units: false
initial concentration: 1.0
type: Species
boundary condition: false
constant: false
name: D-glucose
is: SBO:0000247
notes: FORMULA: C6H12O6 CHARGE: 0 INCHI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00040

http://identifiers.org/biomodels.db/MODEL1109130000#fdf280f6_8a40_4da1_9448_3f66ebdd0031
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a8f83d69_042c_4454_aca2_ed7fe9b31d1c
value: 0.0
type: LocalParameter

metaR EX gln L LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for L-glutamine
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#c5918673_cdb5_46da_9dc7_23309de9da6c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d647d1d2_e33c_4253_93ac_14f47dd8db7d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b1de960a_02f1_40b0_ba4a_2f6aa163459a
value: -1000.0
type: LocalParameter

metaR r0760
is described by: http://identifiers.org/pubmed/7834997
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11750882
name: butyryl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7567999
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false
type: Reaction
notes: GENE_ASSOCIATION: (AI640625.1) or (51733.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
is described by: http://identifiers.org/pubmed/4452359
is described by: http://identifiers.org/pubmed/6137188
product: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/8962082

http://identifiers.org/biomodels.db/MODEL1109130000#_236ff648_d978_4b5d_8932_e890415b23de
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6e69a2c7_3429_4426_8ebe_cb3170568318
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9c262780_6e64_4db3_a144_eb6158c1b233
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_274ab046_768f_4279_9661_4a8971f937ea
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#baf1d573_3602_4576_a297_dd20f7e0b500
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE3180C
product: MODEL1109130000#
fast: false
is: SBO:0000176
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Cholesterol metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11111101 NOTES:
reactant: MODEL1109130000#
name: RE3180
is described by: http://identifiers.org/pubmed/11111101
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_287fe16b_ee09_44fd_8d4e_3fd4de7a4428
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5dbe05b5_8c2e_4380_a1fa_6c25bb7d2843
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_83006e03_cb62_4efc_a591_09238950d648
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e1ddf127_c92b_40aa_bc68_37e6fb50c7ec
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7990882d_1604_42b1_a2e2_12d98c0f8c7e
boundary condition: true
constant: true
type: Species
initial amount: NaN
has only substance units: false
is: SBO:0000252
name: null
is encoded by: hsa:AI378339
initial concentration: NaN

metaM thyox L e
is: SBO:0000247
is: HMDB00248
initial amount: NaN
is: CHEBI:18332
constant: false
name: L-thyroxine
type: Species
notes: FORMULA: C15H11I4NO4 CHARGE: 0 INCHI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00849
initial concentration: 1.0
boundary condition: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#cb4fbfee_ed5d_45ff_811e_220110a27098
value: -1000.0
type: LocalParameter

metaM glc D e
initial concentration: 1.0
has only substance units: false
boundary condition: false
is: HMDB00122
initial amount: NaN
name: D-glucose
is: CHEBI:4167
constant: false
type: Species
is: SBO:0000247
notes: FORMULA: C6H12O6 CHARGE: 0 INCHI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00040

metaR RE1447N
is version of: http://identifiers.org/ec-code/3.1.3.66
notes: GENE_ASSOCIATION: SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: 3.1.3.66 Confidence Level: 0 AUTHORS: PMID:11756679,PMID:7556092,PMID:7567999,PMID:9295334,PMID:9356448 NOTES:
product: MODEL1109130000#
name: RE1447
reversible: true
is described by: http://identifiers.org/pubmed/7556092
is described by: http://identifiers.org/pubmed/9356448
is described by: http://identifiers.org/pubmed/7567999
is: SBO:0000176
type: Reaction
is described by: http://identifiers.org/pubmed/11756679
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/9295334

metaR C4CRNCPT2
product: MODEL1109130000#
type: Reaction
reversible: true
reactant: MODEL1109130000#
is: SBO:0000176
fast: false
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: Biochemica et Biophysica Acta 1486(2000) 1-17, Eur. J. Biochem. 244, 1-14 (1997) FEBS 1997, Biochemica et Biophysica Acta 1546(2001) 21-43. EC Number: NOTES: CPT-2 reaction GENE_ASSOCIATION: 1376.1
modifier: MODEL1109130000#
name: transport of butyryl carnitine in the mitochondrial matrix for final hydrolysis

http://identifiers.org/biomodels.db/MODEL1109130000#_575e531b_955d_4bf3_b4fc_72f277104196
units: dimensionless
value: 0.0
type: LocalParameter

metaM 4abut c
is: SBO:0000247
is: C00334
is: http://identifiers.org/pubchem.substance/3628
boundary condition: false
notes: FORMULA: C4H9NO2 CHARGE: 0 INCHI:
type: Species
constant: false
is: HMDB00112
has only substance units: false
initial amount: NaN
name: 4-Aminobutanoate
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_60ff0a1f_55da_4490_b8e7_20f8304e64ed
value: 0.0
type: LocalParameter

metaR FAOXC16DCC14DCx
type: Reaction
fast: false
is: SBO:0000176
is described by: http://identifiers.org/pubmed/9827430
name: fatty acid beta oxidation(C16DC-->C14DC)x
modifier: MODEL1109130000#
reversible: false
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID:15060085,PMID:9827430 EC Number: NOTES: to acetyl coA and accumulates and then combines with free carnitine and ultimately excreated in urine GENE_ASSOCIATION: (51.1 and 1962.1 and 3295.1 and 30.1)
is described by: http://identifiers.org/pubmed/15060085
reactant: MODEL1109130000#
product: MODEL1109130000#

metaM ksi deg9 l
type: Species
boundary condition: false
name: keratan sulfate I, degradation product 9
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247
has only substance units: false
constant: false
notes: FORMULA: C188H301N13O166S10 CHARGE: -10 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#f71cbe26_af3a_451a_8f14_7753c870db94
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_44bd0993_e01f_40f2_b3c4_128255752625
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V1C1:ATP6V1G2:ATP6V1E2:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#e2e085a6_c5a2_4eda_94cb_7ccf2b4bed76
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3e39cb9e_e209_4c4e_8f57_abc362ba616d
name: PNPO
type: Species
is: Q9NVS9
boundary condition: true
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:55163
has only substance units: false
constant: false
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_9dddd492_a1c6_4f97_be87_bd3045ce4cf8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7cbb1dff_3976_402d_abf3_15627e39b841
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_45ecf968_d24d_4596_beef_4da040449b8f
value: 1000.0
type: LocalParameter

metaR ELAIDt
is version of: ECO:0000000
reversible: true
type: Reaction
name: fatty acid transport via diffusion
is described by: http://identifiers.org/pubmed/12864740
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:11788354,PMID:12864740 NOTES: NJ
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
is: SBO:0000185
is described by: http://identifiers.org/pubmed/11788354

http://identifiers.org/biomodels.db/MODEL1109130000#_8d035586_cb2b_4517_95a4_76574546a16b
name: IDH3A:IDH3B:IDH3G
has only substance units: false
has part: P51553
has part: P50213
is encoded by: hsa:3421
is encoded by: hsa:3419
constant: true
type: Species
boundary condition: true
is encoded by: hsa:3420
initial concentration: NaN
initial amount: NaN
is: SBO:0000297

http://identifiers.org/biomodels.db/MODEL1109130000#_8f6875ac_7d28_4c54_9174_638ac9e66aa1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d4a3ea6b_c4b6_4ff1_8a20_1b811b753e8b
constant: false
initial amount: NaN
is: Q9H1B5
name: XYLT2
boundary condition: true
initial concentration: NaN
is encoded by: hsa:64132
type: Species
is: SBO:0000252
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4d7549db_ccba_4b09_91b8_0057c71764ca
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#abeca03a_0d98_449f_82c2_4216dd6d08c3
value: -1000.0
type: LocalParameter

metaR RE2155R
is version of: http://identifiers.org/ec-code/1.14.99.10
product: MODEL1109130000#
name: RE2155
is described by: http://identifiers.org/pubmed/12376740
is: SBO:0000176
reactant: MODEL1109130000#
fast: false
modifier: MODEL1109130000#
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: 1589.1 SUBSYSTEM: Miscellaneous EC Number: 1.14.99.10 Confidence Level: 0 AUTHORS: PMID:12376740 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#f07278e4_c66d_4e4f_8fb0_266b21059b5e
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaM thyox L c
notes: FORMULA: C15H11I4NO4 CHARGE: 0 INCHI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00849
has only substance units: false
is: HMDB00248
type: Species
is: CHEBI:18332
boundary condition: false
constant: false
name: L-thyroxine
initial concentration: 1.0
initial amount: NaN
is: SBO:0000247

metaM glc D c
initial concentration: 1.0
name: D-glucose
type: Species
has only substance units: false
constant: false
initial amount: NaN
is: CHEBI:4167
boundary condition: false
is: SBO:0000247
notes: FORMULA: C6H12O6 CHARGE: 0 INCHI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00040
is: HMDB00122

http://identifiers.org/biomodels.db/MODEL1109130000#af3b54ba_67c7_4802_914d_cd21702e8c56
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_286b6a1e_a0d0_4649_b8f0_328374163fd3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bfdf31fb_95c1_4b1f_a569_c5de01b4ee2d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3794c228_8ad4_430f_8ed2_097973fbf669
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f2ca9115_4ac7_442d_97aa_940acb243516
units: dimensionless
value: 0.0
type: LocalParameter

metaM 4abut e
is: SBO:0000247
is: C00334
is: http://identifiers.org/pubchem.substance/3628
constant: false
boundary condition: false
is: HMDB00112
type: Species
initial amount: NaN
notes: FORMULA: C4H9NO2 CHARGE: 0 INCHI:
has only substance units: false
initial concentration: 1.0
name: 4-Aminobutanoate

http://identifiers.org/biomodels.db/MODEL1109130000#_1ab919f0_36bd_4a84_9f47_ed02b660d57a
is: SBO:0000252
initial amount: NaN
boundary condition: true
is: Q5DSZ8
initial concentration: NaN
constant: true
is encoded by: hsa:54578
has only substance units: false
name: UGT1A6
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_2ed0d3b0_653c_4f70_8ff7_9aa876e5772e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4661f94c_62a8_4f5a_8809_369e219868ff
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_e0b3c184_fae9_443c_90c9_d6e83bd96a74
initial amount: NaN
type: Species
has only substance units: false
constant: false
boundary condition: true
initial concentration: NaN
is encoded by: hsa:29796
is: Q9UDW1
name: UQCR10
notes: DRUGBANK_UNKNOWN: DB04141, DB04799, DB07401, DB07636, DB07763, DB07778, DB08330, DB08453, DB08690
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_43f26737_99a7_4553_b726_4c90428776b6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1412b9ee_03ac_47e5_b2ff_fd135c90bffe
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9302d7e5_24fc_4d1a_be83_d9175f5bbb0e
is: SBO:0000252
name: LPL
is encoded by: hsa:4023
is: P06858
initial amount: NaN
initial concentration: NaN
boundary condition: true
type: Species
constant: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_999de494_9e5a_4ef3_b321_1b14a67a612e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_13ab0760_7423_4711_9a36_1d1d5bb47ef4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8e5c69e6_26e2_47dc_be6f_1686deeb5331
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_95065d1c_de3d_489a_a36d_add7173561a4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ef2df542_345f_4c1a_aa29_afd6f2fbb946
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B1:ATP6V1C1:ATP6V1E1:ATP6V1F:ATP6V1G1
type: Species

metaR 3SALAASPm
product: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction
name: cysteinesulfinate-aspartate mitochondrial shuttle
fast: false
is described by: http://identifiers.org/pubmed/14598172
reversible: true
notes: GENE_ASSOCIATION: (10165.1) or (8604.1) SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 2 AUTHORS: PMID:14598172 NOTES: PMID:486467 MM
is: SBO:0000185
is version of: ECO:0000304
reactant: MODEL1109130000#

metaM CE2206 c
boundary condition: false
has only substance units: false
is: SBO:0000247
initial amount: NaN
is: CHEBI:47812
initial concentration: 1.0
name: 24-oxo-1alpha,25-dihydroxyvitamin D3
notes: FORMULA: C27H42O4 CHARGE: 0 INCHI: InChI=1S/C27H42O4/c1-17(8-13-25(30)26(3,4)31)22-11-12-23-19(7-6-14-27(22,23)5)9-10-20-15-21(28)16-24(29)18(20)2/h9-10,17,21-24,28-29,31H,2,6-8,11-16H2,1,3-5H3/b19-9+,20-10-/t17-,21-,22-,23+,24+,27-/m1/s1 EHMN_ABBREVIATION: CE2206
constant: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_9e4a4994_c8bf_438b_b166_a57e53e89f3d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b99b41e9_6c8a_4fce_b0ba_e6b3e1027e93
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c0802c7b_cf68_4b11_ba43_d0e0feb75a0d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_16908d96_8243_4123_94bb_e8d76e923989
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9ccc7be5_e07c_4576_a7ad_f7b71a1affbf
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_47dcb41e_ad13_4449_9549_ad3b25913af5
value: 0.0
type: LocalParameter

metaR RE1907C
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:9380738 NOTES:
product: MODEL1109130000#
name: RE1907
is described by: http://identifiers.org/pubmed/9380738
is: SBO:0000176
reactant: MODEL1109130000#
type: Reaction
reversible: true
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#df29c32b_e056_48c0_accb_b6b733f53ca1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c21ac2bd_6e61_4366_8463_85caeac0b542
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5160b602_d6b4_478a_9e20_512207e397fa
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6ec5def3_38cb_4031_94bf_fca83e16607e
value: 0.0
type: LocalParameter

metaM CE1941 c
initial concentration: 1.0
boundary condition: false
initial amount: NaN
constant: false
is: SBO:0000247
type: Species
notes: FORMULA: C7H17N2O2 CHARGE: 1 INCHI: InChI=1/C7H16N2O2/c8-4-2-6-9-5-1-3-7(10)11/h9H,1-6,8H2,(H,10,11) EHMN_ABBREVIATION: CE1941
has only substance units: false
name: isoputreanine
is: HMDB06009

http://identifiers.org/biomodels.db/MODEL1109130000#e52c352b_256b_4d1e_864c_30d79fa0d55f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_84602ed8_8801_4096_999e_e7d4603c24c3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3bcdf05f_1afe_4761_ac90_2d11bad1dadf
value: 0.0
type: LocalParameter

metaR TREH
reversible: false
is: SBO:0000176
type: Reaction
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
is version of: ECO:0000254
modifier: MODEL1109130000#
name: alpha,alpha-trehalase
is version of: http://identifiers.org/ec-code/3.2.1.28
notes: GENE_ASSOCIATION: 80162.1 SUBSYSTEM: Starch and sucrose metabolism EC Number: 3.2.1.28 Confidence Level: 2 AUTHORS: NOTES: IF

metaR GALASE18ly
is: SBO:0000176
name: beta-galactosidase, lysosomal
is described by: http://identifiers.org/pubmed/2111707
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8985184
is described by: http://identifiers.org/pubmed/11550799
is described by: http://identifiers.org/pubmed/1953646
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7213753
is described by: http://identifiers.org/pubmed/7575473
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/39554
notes: GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) or (5476.1) and (2720.1) SUBSYSTEM: Keratan sulfate degradation EC Number: 3.2.1.23 Confidence Level: 4 AUTHORS: PMID:11550799,PMID:1755850,PMID:1794986,PMID:1953646,PMID:2111707,PMID:3143362,PMID:39554,PMID:7213753,PMID:7575473,PMID:8985184,PMID:9020182,PMID:9054950 NOTES: NCD
is described by: http://identifiers.org/pubmed/3143362
is described by: http://identifiers.org/pubmed/9054950
is version of: http://identifiers.org/ec-code/3.2.1.23
reversible: false
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/1755850
type: Reaction
is described by: http://identifiers.org/pubmed/9020182
is described by: http://identifiers.org/pubmed/1794986

http://identifiers.org/biomodels.db/MODEL1109130000#_44591e85_fe6d_4a7e_b785_ea439462794f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0babb73f_e88f_4075_b02a_992b2041bc50
value: 0.0
type: LocalParameter

metaR r0702
fast: false
reversible: true
modifier: MODEL1109130000#
name: (3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase Fatty acid biosynthesis EC:2.3.1.85
reactant: MODEL1109130000#
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.85
notes: GENE_ASSOCIATION: (30.1) or (10449.1) or (3032.1) or (4645.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
type: Reaction
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7567999

http://identifiers.org/biomodels.db/MODEL1109130000#_5f7feb4d_9209_45b9_a1a7_823f543b998a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1f5a1915_11b0_4629_b290_2e9ca47dcc38
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2cdc7ccb_06ee_4193_b680_a36ac71cf9ed
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a88365e4_11ac_4cc1_acb1_566f26f52413
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24badec9_cdae_4ea6_9166_3c0778d01b75
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_690027ab_1464_4c6d_8580_488ed5b6439d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e04aaed1_7d0b_4b7d_9685_6b2e8272a8f0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_23f22234_ea53_427b_b08e_d7e0296e75b7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6f45bd07_3bf0_4d16_ac00_ed20caf1b261
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0701
is described by: http://identifiers.org/pubmed/7834997
is described by: http://identifiers.org/pubmed/11750882
notes: GENE_ASSOCIATION: (AA526438.1) or (H17063.1) or (51102.1) or (55825.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
reversible: true
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8962082
name: (3R)-3-Hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase Fatty acid biosynthesis EC:2.3.1.85
type: Reaction
is described by: http://identifiers.org/pubmed/6137188
is described by: http://identifiers.org/pubmed/7567999
is version of: http://identifiers.org/ec-code/2.3.1.85
is: SBO:0000176
is described by: http://identifiers.org/pubmed/4452359
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_54cf29e0_bccd_44dd_98d5_37c835de0239
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b2500625_0703_441e_ac33_e4fbd52e3a90
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1C2:ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B1:ATP6V1E1:ATP6V1G2:ATP6V1F
type: Species

metaR HSD3B13r
is described by: http://identifiers.org/pubmed/12205101
notes: GENE_ASSOCIATION: 3284.1 SUBSYSTEM: Steroid metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:12205101 NOTES: Human 3betaHSD type1 recombinantly expressed in baculovirus, kinetic parameters determined using 17alpha-hydroxypregnenolone as substrate and isomerase activity quantified with dehydroepiandrosterone as substrate
modifier: MODEL1109130000#
product: MODEL1109130000#
is version of: ECO:0000134
type: Reaction
reversible: false
is: SBO:0000176
name: 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I
reactant: MODEL1109130000#
fast: false

metaR RE1835C
is described by: http://identifiers.org/pubmed/10817395
reactant: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
product: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/11454857
name: RE1835
is version of: http://identifiers.org/ec-code/3.1.2.2
notes: GENE_ASSOCIATION: (641372.1) or (641371.1) or (570.1) SUBSYSTEM: Bile acid synthesis EC Number: 3.1.2.2 Confidence Level: 0 AUTHORS: PMID:10817395,PMID:10944470,PMID:11454857,PMID:11673457 NOTES: IT - fixed proton
type: Reaction
is described by: http://identifiers.org/pubmed/10944470
is described by: http://identifiers.org/pubmed/11673457
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#ecf23c79_c8aa_4231_bd37_d2f73c4b6368
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eb551e41_a525_4ea1_b4b1_07ff7df7f0dd
value: 0.0
type: LocalParameter

metaM hs deg1 l
boundary condition: false
name: heparan sulfate, degradation product 1
initial concentration: 1.0
type: Species
notes: FORMULA: C79H115N5O99S11 CHARGE: -12
initial amount: NaN
constant: false
is: SBO:0000247
has only substance units: false

metaR RE3557R
name: RE3557
modifier: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9755286
reversible: true
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (4259.1) or (4258.1) or (4257.1) SUBSYSTEM: Eicosanoid metabolism EC Number: 2.5.1.18 Confidence Level: 0 AUTHORS: PMID:9755286 NOTES:
fast: false
is version of: http://identifiers.org/ec-code/2.5.1.18
is: SBO:0000176

metaM CE5653 r
type: Species
has only substance units: false
is: SBO:0000247
initial concentration: 1.0
constant: false
initial amount: NaN
notes: FORMULA: C20H25O3 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5653
name: 4-oxo-9-cis-retinoate
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_9fc4ee54_ceb5_4649_af47_a9089682e35e
initial concentration: NaN
is: O75521
is: SBO:0000252
has only substance units: false
initial amount: NaN
boundary condition: true
name: ECI2
constant: false
notes: DRUGBANK_UNKNOWN: DB08231
is encoded by: hsa:10455
type: Species

metaM 3m4hpga m
is: SBO:0000247
initial concentration: 1.0
is: http://identifiers.org/pubchem.substance/7909
is: C05583
has only substance units: false
type: Species
initial amount: NaN
notes: FORMULA: C9H10O4 CHARGE: 0 INCHI: InChI=1/C9H10O4/c1-13-9-4-6(8(12)5-10)2-3-7(9)11/h2-5,8,11-12H,1H3 HEPATONET_1.0_ABBREVIATION: HC01520 EHMN_ABBREVIATION: C05583
boundary condition: false
constant: false
name: 3-Methoxy-4-hydroxyphenylglycolaldehyde
is: HMDB04061

metaM damp c
notes: FORMULA: C10H12N5O6P CHARGE: -2 INCHI: InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/p-2/t5-,6+,7+/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00304 EHMN_ABBREVIATION: C00360
is: HMDB00905
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0
type: Species
is: CHEBI:58245
initial amount: NaN
is: SBO:0000247
name: dAMP(2-)

metaM f5hoxkyn c
constant: false
is: http://identifiers.org/pubchem.substance/7958
is: C05647
is: SBO:0000247
has only substance units: false
type: Species
name: Formyl-5-hydroxykynurenamine
notes: FORMULA: C10H13N2O3 CHARGE: 1 INCHI: InChI=1/C10H12N2O3/c11-4-3-10(15)8-5-7(14)1-2-9(8)12-6-13/h1-2,5-6,14H,3-4,11H2,(H,12,13) EHMN_ABBREVIATION: C05647
boundary condition: false
initial concentration: 1.0
initial amount: NaN
is: HMDB12948

http://identifiers.org/biomodels.db/MODEL1109130000#e68970ee_e449_4063_b384_5d3a637ac9f1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_619f5964_daa1_4136_88c5_efe814f201a5
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b8f502b_33b6_4d0d_9c84_60afb2ee8b4b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d281df63_4c12_482d_a384_4c5caa191b45
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e6d35203_0096_4131_bf1c_2ea735cbcfc2
value: 1000.0
type: LocalParameter

metaR AGTix
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9038835
is: SBO:0000176
reversible: false
is described by: http://identifiers.org/pubmed/9783918
is version of: ECO:0000269
notes: GENE_ASSOCIATION: 189.1 SUBSYSTEM: Alanine and aspartate metabolism EC Number: 2.6.1.44 Confidence Level: 4 AUTHORS: PMID:1703535,PMID:9038835,PMID:9783918 NOTES: NCD
is version of: http://identifiers.org/ec-code/2.6.1.44
fast: false
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1703535
name: alanine-glyoxylate transaminase (irreversible), (peroxisomal)
type: Reaction
product: MODEL1109130000#

metaR EX mepi LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Metanephrine exchange
type: Reaction

metaM CE5236 c
type: Species
constant: false
is: SBO:0000247
initial concentration: 1.0
boundary condition: false
initial amount: NaN
name: O2-4a-cyclic-tetrahydrobiopterin
notes: FORMULA: C9H13N5O3 CHARGE: 0 INCHI: InChI=1/C9H13N5O3/c1-3-5(15)4-2-11-6-9(14-4,17-3)7(16)13-8(10)12-6/h3-5,14-15H,2H2,1H3,(H3,10,11,12,13,16)/p+1/t3-,4u,5+,9u/m0/s1 EHMN_ABBREVIATION: CE5236
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_2665a05d_2d2b_45e3_a8e1_962b234efffc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9414a6bd_5c5e_4abf_8668_d53ab58d9786
initial amount: NaN
constant: false
is: SBO:0000252
has only substance units: false
boundary condition: true
is encoded by: hsa:1808
type: Species
name: DPYSL2
initial concentration: NaN
is: B4DR31

http://identifiers.org/biomodels.db/MODEL1109130000#_4008292a_63bb_4db9_b866_ad4cfeacd2e4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2dbafff0_1c1f_4449_ad26_13dcf531f481
type: Species
has part: P07237
initial concentration: NaN
is: SBO:0000297
initial amount: NaN
is encoded by: hsa:5034
name: P4HB:P4HA2
is encoded by: hsa:8974
constant: true
has part: Q05DA4
boundary condition: true
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_95709032_76ee_46a1_93a9_98dd063a843d
value: -1000.0
type: LocalParameter

metaR XOLEST2HSTDle
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 2 AUTHORS: Sareen S. Gropper, jack L. Smith, James L. Groff (2009) Wadaworth cengage learning, Advanced nutrition and human metabolism, 5th edition, page 142-148. EC Number: NOTES: transported in chylomicrons into lymph GENE_ASSOCIATION:
is: SBO:0000185
fast: false
reversible: false
name: XOLEST2HSTDle
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_76cd1204_a3bd_471f_9a62_de5d58ea5708
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_162ed1fc_e636_4019_ac4b_7b394cab27bb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_242869a2_42c8_4275_8cb3_08b89d573262
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9d3ad141_ce3c_46cc_9246_5b4a36f62eb9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8f3c8650_6919_4358_a977_898e0afbb0ef
units: dimensionless
value: 0.0
type: LocalParameter

metaR CSPG Dt
product: MODEL1109130000#
reactant: MODEL1109130000#
name: chondroitin sulfate D transport, golgi to extracellular
is version of: ECO:0000000
fast: false
is: SBO:0000185
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES:
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#c795405e_1855_44ee_b0cb_7b5ddb0e05ed
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a6b26acf_4644_49a8_b286_d71c3e515cfa
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_43ac2a6d_7e44_41db_ad27_deec302008f5
units: dimensionless
value: 0.0
type: LocalParameter

metaR BALAVECSEC
type: Reaction
is described by: http://identifiers.org/pubmed/15383652
reactant: MODEL1109130000#
is version of: ECO:0000269
is: SBO:0000185
notes: GENE_ASSOCIATION: 140679.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:12750892,PMID:15383652 NOTES: SAB This reaction represents the ATP driven secretion of glu from the cell. It leaves out the vesicle because a compartment is not available for that. ATP demand is not known for sure stoichiometrically, but 1:1 H coupling ratio is assumed, which could translate to 3 b-ala/ATP.
reversible: false
name: B-alanine secretion via secretory vesicle (ATP driven)
is described by: http://identifiers.org/pubmed/12750892
product: MODEL1109130000#
fast: false
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#d5691aa1_2c63_4a61_b371_fa6fa751715f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a385388f_7b2d_4cc8_b8b7_37febe48e0c7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1b067067_a001_41b3_9778_42d63b546055
value: 0.0
type: LocalParameter

metaR ACt2m
name: acetate mitochondrial transport via proton symport
is: SBO:0000185
is described by: http://identifiers.org/pubmed/10198029
type: Reaction
reversible: true
product: MODEL1109130000#
is version of: ECO:0000000
fast: false
is described by: http://identifiers.org/pubmed/15755952
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 2 AUTHORS: PMID:10198029,PMID:15755952 NOTES: NCD

http://identifiers.org/biomodels.db/MODEL1109130000#b52a1f8d_daf3_41c9_b7f1_48189f1d5071
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ddf63cf7_f85e_49eb_9af8_af2b72912f5c
units: dimensionless
value: 0.0
type: LocalParameter

metaR B3GALT42g
reactant: MODEL1109130000#
fast: false
type: Reaction
name: Beta-1,3-galactosyltransferase 4
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.62
is: SBO:0000176
reversible: false
product: MODEL1109130000#
is version of: ECO:0000000
notes: GENE_ASSOCIATION: 8705.1 SUBSYSTEM: Sphingolipid metabolism EC Number: 2.4.1.62 Confidence Level: 4 AUTHORS: NOTES: NJ

metaR r0706
type: Reaction
product: MODEL1109130000#
name: acyl-Coenzyme A dehydrogenase family, member 9 Bile acid biosynthesis EC:1.3.3.6
is described by: http://identifiers.org/pubmed/11356170
fast: false
reactant: MODEL1109130000#
is: SBO:0000176
notes: GENE_ASSOCIATION: (34.1) or (3712.1) or (R14373.1) SUBSYSTEM: Bile acid synthesis EC Number: 1.3.3.6 Confidence Level: 0 AUTHORS: PMID:11356170,PMID:8943006 NOTES: RE1814X
modifier: MODEL1109130000#
reversible: false
is version of: http://identifiers.org/ec-code/1.3.3.6
is described by: http://identifiers.org/pubmed/8943006

http://identifiers.org/biomodels.db/MODEL1109130000#aa6725fb_7361_48c1_ac7b_bfdfc65802e4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e1c96b01_f06b_48ee_8b24_6a28dcbfb235
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ba5c9f7b_a60f_465e_a15f_2405971a5be4
value: 1000.0
type: LocalParameter

metaR RE3557M
type: Reaction
name: RE3557
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (2954.1) or (4257.1) or (373156.1) SUBSYSTEM: Eicosanoid metabolism EC Number: 2.5.1.18 Confidence Level: 0 AUTHORS: PMID:9755286 NOTES:
modifier: MODEL1109130000#
reversible: true
is: SBO:0000176
fast: false
is described by: http://identifiers.org/pubmed/9755286
is version of: http://identifiers.org/ec-code/2.5.1.18

http://identifiers.org/biomodels.db/MODEL1109130000#_1b2c1835_0266_4a63_8b1e_8f7fe833885c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f7e2d5e4_e61f_41ef_83ec_497d0964fb68
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f39743e5_61e1_4126_9f65_17fc2ed434de
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9fa92655_61f2_43f6_a14f_2acb77e39ad4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_448c8248_6c1f_4247_b243_808673020011
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cdfb6fd2_9903_4c60_8aca_9e3c93683e8a
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaR NACHEXA9ly
name: beta-N-acetylhexosaminidase A, lysosomal
product: MODEL1109130000#
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Keratan sulfate degradation EC Number: Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: Note that this reaction is specific to beta-N-acetylhexosaminidase A and cannot be catalyzed by beta-N-acetylhexosaminidase B (or presumably beta-N-acetylhexosaminidase S). This is also a lumped reaction, representing the cleavage of GalNAc4S or GalNAc6S and N-acetylgalactosamine 4-sulfatase or 6-sulfatase. NCD
is described by: http://identifiers.org/pubmed/11707436
is version of: ECO:0000000
is: SBO:0000176
fast: false
is described by: http://identifiers.org/pubmed/10336991
type: Reaction
is described by: http://identifiers.org/pubmed/8993162
is described by: http://identifiers.org/pubmed/12706724
reactant: MODEL1109130000#
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#db35a301_8e31_4fc3_ad0d_6230c9006b70
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1b9c64ae_34bf_4f9f_be59_e669bffdb247
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_166fa7ce_9354_4584_86b8_d857588941f8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2823f746_63e8_4710_b09b_f2c820f59b5a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5a750874_e4ae_449c_9bf3_bbefb5b0d76a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cbb6bcf0_a78a_467d_a003_4750b8fae76c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7bb52001_5c09_4ab5_b470_eff5f29370a9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_59557d42_6eb4_4057_ac57_76750091c851
value: 0.0
type: LocalParameter

metaR G6PDH2rer
is: SBO:0000176
reversible: true
is version of: http://identifiers.org/ec-code/1.1.1.47
type: Reaction
is described by: http://identifiers.org/pubmed/10349511
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12831846
fast: false
product: MODEL1109130000#
name: glucose 6-phosphate dehydrogenase, endoplasmic reticulum
reactant: MODEL1109130000#
is version of: ECO:0000269
notes: GENE_ASSOCIATION: 9563.1 SUBSYSTEM: Pentose phosphate pathway EC Number: 1.1.1.47 Confidence Level: 4 AUTHORS: PMID:10349511,PMID:12831846,PMID:2156506 NOTES: NCD
is described by: http://identifiers.org/pubmed/2156506

metaR RN0001C
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Selenoamino acid metabolism EC Number: 1.14.13.8 Confidence Level: 0 AUTHORS: NOTES:
reversible: false
reactant: MODEL1109130000#
is: SBO:0000176
type: Reaction
name: RN0001
is version of: http://identifiers.org/ec-code/1.14.13.8

metaR FA161ACPH
is version of: http://identifiers.org/ec-code/3.1.2.14
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/9159116
product: MODEL1109130000#
fast: false
type: Reaction
notes: GENE_ASSOCIATION: 55301.1 SUBSYSTEM: Fatty acid oxidation EC Number: 3.1.2.14 Confidence Level: 4 AUTHORS: PMID:9159116 NOTES: NCD
is: SBO:0000176
reversible: true
reactant: MODEL1109130000#
name: fatty-acyl-ACP hydrolase
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_76f5d84f_c2bf_4a1c_a1b3_26db2e62d256
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f8c6d29_4ecc_4f8c_bc00_c6415920ed6c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dfe21aef_8ad2_4201_a06b_e66511b1741a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1945cf52_aad9_4d97_968b_60e90c8837cc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bc34abd1_983f_4e32_8740_20f0d08f9d5d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_32057901_c100_40ea_9d46_f2810de9e5e0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_09e69ef9_1bc3_4f3c_b096_7e44d82b27c0
value: 0.0
type: LocalParameter

metaR GALSGLT1le
is: SBO:0000185
reversible: false
name: transport of D-Galactose from extracellular space to cytosol of mucosal cells in small intestine
is described by: http://identifiers.org/pubmed/14642859
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 20522896, PMID: 14642859, Sareen S. Gropper, Jack L. Smith, James L. Groff (2009) Advanced nutrition and human metabolism, Wadsworth cengage learning, 5th edition, page 71-72 EC Number: NOTES: SGLT-1 can also transport sugars coupled with H+ instead of Na+, under conditions of decreased extra-cellular ph. However, the affinity for glucose decreases with H+ coupled transport. (PMID: 17468205). The transport system is energized by Na/K ATPase activity (PMID: 7730974, Journal of animal science (2001) volume 79, (E suppl) E59:E72). Reversible transport for SGLT-1 has been suggested in a 6-state model in PMCID: PMC3000923. GENE_ASSOCIATION: 6523.1
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/20522896
reactant: MODEL1109130000#
type: Reaction
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_223390d9_6c9e_408f_be82_1fcebe19b49e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69968a89_d690_42a9_b658_1f508f2e8588
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4995d808_7f1d_4e5d_a7f9_af382cd71e4e
boundary condition: true
has part: O00459
is encoded by: hsa:5291
initial amount: NaN
name: PIK3CB:PIK3R2
has part: B4DER4
initial concentration: NaN
constant: true
is encoded by: hsa:5296
has only substance units: false
is: SBO:0000297
type: Species

metaR PNTOt5
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15561972
is described by: http://identifiers.org/pubmed/10329687
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/10334869
type: Reaction
modifier: MODEL1109130000#
reversible: false
product: MODEL1109130000#
name: Pantothenate sodium symporter II
is: SBO:0000185
is described by: http://identifiers.org/pubmed/12646417
notes: GENE_ASSOCIATION: 8884.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:10329687,PMID:10334869,PMID:12646417,PMID:15561972,PMID:9516450 NOTES: _01-25-05 based on Wang et al., JBC, 1999,1 274(21), 14875-14888. IT 03-07-05:replaced IT: now based on Balamurugan et al, 2005, Am J Physiol Renal Physiol, 288, F823-831,2005
is described by: http://identifiers.org/pubmed/9516450
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#a5b63c27_ee14_4f83_9811_556dade4e64a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2cba0c5_c8e2_4029_9f99_7feafc587c70
value: 1000.0
type: LocalParameter

metaR ACt2r
name: acetate reversible transport via proton symport
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:9651205 NOTES: NCD
reactant: MODEL1109130000#
is: SBO:0000185
product: MODEL1109130000#
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/9651205
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_e6c2ee80_ae40_4302_88eb_d98eb4336352
boundary condition: true
is: SBO:0000252
is encoded by: hsa:4706
initial amount: NaN
is: O14561
type: Species
initial concentration: NaN
has only substance units: false
name: NDUFAB1
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6ec1974c_1b53_4231_b00a_ee33dd4b03e5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_34204638_a5c4_4ffa_9290_f6a472d16fa9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cf1e036b_b606_4b4a_938d_c7534f42af6e
value: -1000.0
type: LocalParameter

metaR 2OXOADPTm
name: 2-oxoadipate shuttle (cytosol/mitochondria)
reactant: MODEL1109130000#
product: MODEL1109130000#
is: SBO:0000185
type: Reaction
notes: GENE_ASSOCIATION: 89874.1 SUBSYSTEM: Tryptophan metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:11083877 NOTES: SAB PMID 11083877
is version of: ECO:0000269
modifier: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/11083877
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#a1ee5daa_bb4f_4c44_a318_43d31016afa0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_81736d9b_c55b_483e_8a48_da42ac8aca58
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6d03e4b9_e501_49c3_a566_d7883a6f418a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ac55c4c1_9eac_45cb_b582_44886f4a580e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a8dee92_f416_48f5_8856_5b9fb4a7897b
value: 0.0
type: LocalParameter

metaM phyt2ohcoa x
type: Species
is: HMDB01295
initial concentration: 1.0
notes: FORMULA: C41H70N7O18P3S CHARGE: -4 INCHI: InChI=1S/C41H74N7O18P3S/c1-25(2)11-8-12-26(3)13-9-14-27(4)15-10-16-28(5)32(50)40(54)70-20-19-43-30(49)17-18-44-38(53)35(52)41(6,7)22-63-69(60,61)66-68(58,59)62-21-29-34(65-67(55,56)57)33(51)39(64-29)48-24-47-31-36(42)45-23-46-37(31)48/h23-29,32-35,39,50-52H,8-22H2,1-7H3,(H,43,49)(H,44,53)(H,58,59)(H,60,61)(H2,42,45,46)(H2,55,56,57)/p-4/t26?,27?,28?,29-,32?,33-,34-,35+,39-/m1/s1 EHMN_ABBREVIATION: C07343
is: SBO:0000247
is: CHEBI:57334
constant: false
initial amount: NaN
has only substance units: false
name: 2-hydroxyphytanoyl-CoA(4-)
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#f006678e_2f0c_4afc_9524_5456e31d0569
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b9bbb4c0_0e8b_4090_900a_900c0dd1f288
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE3108C
reversible: true
is: SBO:0000176
name: RE3108
is version of: http://identifiers.org/ec-code/1.1.1.50
type: Reaction
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/11134149
is described by: http://identifiers.org/pubmed/10487690
notes: GENE_ASSOCIATION: SUBSYSTEM: Androgen and estrogen synthesis and metabolism EC Number: 1.1.1.50 Confidence Level: 0 AUTHORS: PMID:10487690,PMID:11134149 NOTES:
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_365de1b4_9344_4c1f_a954_73d1f2b5d87f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74b53e5a_1ae0_4d46_b397_413c014b62a5
units: dimensionless
value: 0.0
type: LocalParameter

metaR GLUTCOAACBP
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/20511713
is described by: http://identifiers.org/pubmed/16908521
reactant: MODEL1109130000#
product: MODEL1109130000#
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/8001684
is described by: http://identifiers.org/pubmed/11859412
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 3 AUTHORS: PMID: 20511713, PMID: 11859412, PMID: 16908521, PMID: 8001684 EC Number: NOTES: acyl coA binding protein is localized in cytosol, nucelus, golgi, E.R., mitochondrial inter memebrane space. In mitochondria its released when the integrity of the organelle is compromised. It has wide role in lipid metabolism, also acts as a coA transporter between different cellular compartments. can transport accumulated acyl coAs from cutosol into mitochondria for beta oxidation or into cytosol for either transport into other compartemnts or for elliciting signalling cascades. GENE_ASSOCIATION: 1622.1
reversible: true
name: transport of glutaryl-CoA(5-) from mitochondria into cytosol
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#c0125cd6_c106_4baa_a64b_f8269fb770f0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6dab81ed_c376_48a0_a8d5_ed3b0e288927
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_04932499_181c_4ad6_90b3_148bacc6d12f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d13a8f7b_47ce_4b12_ab3b_61df40871f24
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_578bf48e_bec3_4ff7_9eb5_5c89737f2d04
units: dimensionless
value: 0.0
type: LocalParameter

metaR DMATT
reversible: false
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/17477828
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 9453.1 SUBSYSTEM: Cholesterol metabolism EC Number: 2.5.1.1 Confidence Level: 2 AUTHORS: PMID:17477828,PMID:17477829 NOTES: Human Y/N: Y
name: dimethylallyltranstransferase
reactant: MODEL1109130000#
is version of: ECO:0000134
is version of: http://identifiers.org/ec-code/2.5.1.1
type: Reaction
is described by: http://identifiers.org/pubmed/17477829
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_16fe8730_d732_4654_8c70_1e400352ed4b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_19e13480_d28d_4726_8b4c_665f405fb48d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6115e11d_edaa_4355_9565_b515a96a1856
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC02026 r
initial amount: NaN
boundary condition: false
constant: false
has only substance units: false
type: Species
name: Cholesterol-ester-gla
notes: FORMULA: CHARGE: 0
is: SBO:0000247
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_3b0be94a_39fe_4702_97f4_94014a9db05f
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1375
notes: GENE_ASSOCIATION: SUBSYSTEM: Aminosugar metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:17267599 NOTES:
fast: false
is: SBO:0000185
product: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/17267599
name: Transport reaction
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_5611e626_6b61_4748_a79b_a866e258fb01
value: 1000.0
type: LocalParameter

metaM C14849 c
name: Benzo[a]pyrene-9,10-oxide
is: C14849
has only substance units: false
initial concentration: 1.0
is: SBO:0000247
initial amount: NaN
constant: false
boundary condition: false
notes: FORMULA: C20H12O CHARGE: 0 INCHI: InChI=1/C20H12O/c1-2-11-4-5-13-10-14-7-9-16-20(21-16)19(14)15-8-6-12(3-1)17(11)18(13)15/h1-10,16,20H EHMN_ABBREVIATION: C14849
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#aecbc54d_1966_4839_b29f_386cc1bfe282
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7dc24bc0_b4ed_4b38_afe9_9071ece59e33
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7e538868_f456_4ddf_bfec_2ab622544abf
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e12e8116_6219_4798_9c78_c829c265d08a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_23aa460b_e7e1_4554_a51e_59ad831af7e6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b32430c5_4768_49bd_bdf9_f7e78a89104e
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1378
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.1.1.284
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Unassigned EC Number: 1.1.1.284 Confidence Level: 0 AUTHORS: PMID:18288723 NOTES:
fast: false
name: S-(hydroxymethyl)glutathione dehydrogenase Methane metabolism EC:1.1.1.284
type: Reaction
reversible: true
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/18288723

http://identifiers.org/biomodels.db/MODEL1109130000#_814b7196_c756_443d_b368_6de41592f500
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_963fc3ad_42c8_427e_ac3f_d11631a6788b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_53336577_0bba_4111_8910_c2f36ed883ff
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1e0a3a5f_65a6_4918_883c_bab96fd4e422
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7cabe839_db91_4cca_aad8_379c3c45b80c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a7a59e5_3b3d_46fe_b0ed_89089f4043d0
value: 0.0
type: LocalParameter

metaM damp l
is: HMDB00905
initial amount: NaN
is: CHEBI:58245
type: Species
initial concentration: 1.0
name: dAMP(2-)
is: SBO:0000247
constant: false
notes: FORMULA: C10H12N5O6P CHARGE: -2 INCHI: InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/p-2/t5-,6+,7+/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00304 EHMN_ABBREVIATION: C00360
boundary condition: false
has only substance units: false

metaR r1377
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Unassigned EC Number: 4.4.1.22 Confidence Level: 0 AUTHORS: NOTES:
name: S-(hydroxymethyl)glutathione synthase Methane metabolism EC:4.4.1.22
is version of: http://identifiers.org/ec-code/4.4.1.22
type: Reaction
reversible: true
product: MODEL1109130000#
fast: false
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_68c418e9_5af6_4f31_b234_a9a88b074701
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8833f03f_64f1_4a65_9337_af01bbcdd2a8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e9f4a152_bc39_408e_a037_986bc11d288f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_f9a52bfb_c17c_4d05_8817_082339980baf
notes: DRUGBANK_UNKNOWN: DB00157
is encoded by: hsa:3030
has part: P49748
has part: P55084
is encoded by: hsa:3032
constant: true
type: Species
name: HADHA:HADHB:ACADVL
boundary condition: true
has only substance units: false
is encoded by: hsa:37
is: SBO:0000297
has part: P40939
initial amount: NaN
initial concentration: NaN

metaR G14T10g
is described by: http://identifiers.org/pubmed/3094506
notes: GENE_ASSOCIATION: (9334.1) or (2683.1) or (8703.1) or (8704.2) or (8704.1) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.1.38 Confidence Level: 4 AUTHORS: PMID:12512857,PMID:1903938,PMID:3094506,PMID:3144273,PMID:9405390,PMID:9435216 NOTES: Keratan sulfate I biosynthesis NCD
product: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9435216
is described by: http://identifiers.org/pubmed/12512857
is version of: http://identifiers.org/ec-code/2.4.1.38
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/1903938
fast: false
modifier: MODEL1109130000#
name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi
is: SBO:0000176
type: Reaction
is described by: http://identifiers.org/pubmed/9405390
is described by: http://identifiers.org/pubmed/3144273
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4f223037_bf7b_4a32_9e23_86b7499c5814
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1571c073_4163_4d0d_a44c_93049a8e9dc9
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e00008e2_2719_4d98_a4a0_4531ad363b00
value: 0.0
type: LocalParameter

metaM CE1957 c
initial concentration: 1.0
name: 4-hydroxy-3-nitrophenylacetate
boundary condition: false
constant: false
notes: FORMULA: C8H5NO5 CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE1957
type: Species
initial amount: NaN
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#cb98e50d_a8dc_4b1b_88b8_d90da29dc6bf
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1706b917_e4f5_4f58_a98c_7fe38274dedd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3e163648_d711_4635_9357_1c9e4de764f3
value: 0.0
type: LocalParameter

metaR RE1906R
name: RE1906
notes: GENE_ASSOCIATION: 1544.1 SUBSYSTEM: Vitamin A metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:9647871 NOTES:
modifier: MODEL1109130000#
fast: false
type: Reaction
reversible: false
is: SBO:0000176
product: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9647871

http://identifiers.org/biomodels.db/MODEL1109130000#_10dfdeed_32c0_42e9_af22_8dd41f7d2842
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b2fd9d80_e3d9_46dc_901b_cc9ea952ffa1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_09de3795_e1b1_4688_9967_c96986cc34b6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3dcab231_6ce7_4daa_9bbd_2beb3cddfba7
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_208cb788_d26a_4620_b4d5_f74397039ffe
value: 0.0
type: LocalParameter

metaR RE1099R
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 412.1 SUBSYSTEM: Steroid metabolism EC Number: 3.1.6.2 Confidence Level: 0 AUTHORS: PMID:10049998,PMID:1606923 NOTES:
is described by: http://identifiers.org/pubmed/10049998
fast: false
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1606923
modifier: MODEL1109130000#
reversible: true
is: SBO:0000176
name: RE1099
is version of: http://identifiers.org/ec-code/3.1.6.2

http://identifiers.org/biomodels.db/MODEL1109130000#_7608f99c_a9cb_4f61_9b7d_aea8993bfc92
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5127a21f_aab0_456a_bfcc_dcd1390b632f
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b4fd3dd8_a20c_49fc_a3eb_a10cec221dd3
value: 1000.0
type: LocalParameter

metaR EX tdechola LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for Taurodeoxycholic acid
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#bc1bf947_943d_4e1d_be1d_7925101700e2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ce1b948d_8f57_4c29_b145_a051699ba35e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b71d799_c01f_46d9_aefd_4bf07f4b3ac2
is encoded by: hsa:55586
has only substance units: false
initial concentration: NaN
is: SBO:0000252
boundary condition: true
type: Species
initial amount: NaN
constant: true
is: Q9UGB7
name: MIOX

http://identifiers.org/biomodels.db/MODEL1109130000#_0ec60427_f830_4af9_8a6e_a379f3c0c34f
is: SBO:0000252
initial amount: NaN
boundary condition: true
has only substance units: false
constant: false
is: O76062
initial concentration: NaN
name: TM7SF2
type: Species
is encoded by: hsa:7108

metaM cgly e
is: CHEBI:4047
initial concentration: 1.0
is: HMDB00078
initial amount: NaN
notes: FORMULA: C5H10N2O3S CHARGE: 0 INCHI: InChI=1S/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9)/t3-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00784 EHMN_ABBREVIATION: C01419
type: Species
has only substance units: false
is: SBO:0000247
name: L-cysteinylglycine
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#f70b3752_6e68_48ba_bdd3_eedacfc37ada
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

metaR r1374
notes: GENE_ASSOCIATION: SUBSYSTEM: Aminosugar metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:17267599 NOTES:
fast: false
is: SBO:0000176
reversible: false
reactant: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/17267599
product: MODEL1109130000#
name: EC:3.2.1.14

http://identifiers.org/biomodels.db/MODEL1109130000#_3f3915ce_d835_441c_ad1b_5d49afb9807c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d796671c_0936_496c_8386_31365da45ddd
boundary condition: true
has only substance units: false
is: SBO:0000252
name: SLC37A4
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:2542
constant: false
is: A8K0S7
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_7f5e66e8_0e98_417d_85be_ebc805491fcc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_78892d9e_3399_40d4_91e0_ab02ac541e95
initial concentration: NaN
boundary condition: true
is: O14832
is: SBO:0000252
notes: DRUGBANK_UNKNOWN: DB00126 DRUGBANK_ANTAGONIST: DB00025
type: Species
initial amount: NaN
has only substance units: false
name: PHYH
is encoded by: hsa:5264
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_25d851fc_d24e_4aee_aa18_347d184c7ae9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4b0eed85_84b3_4630_a2c9_0a70cb57b623
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_02d714c3_cfec_4123_af5d_b1534f0e7554
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1d5964ac_fbb8_483e_b482_4c33d69a8c14
value: 0.0
type: LocalParameter

metaM cs c d e pre1 g
is: SBO:0000247
notes: FORMULA: C31H47NO31S2X CHARGE: -3 INCHI:
initial amount: NaN
initial concentration: 1.0
has only substance units: false
type: Species
name: chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_36243a05_da4e_4dd5_894a_b1599f868ba0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8a4d799a_d276_4b7d_9c8e_4f42daf1f5d1
value: 0.0
type: LocalParameter

metaR TRDR
product: MODEL1109130000#
reversible: false
type: Reaction
name: thioredoxin reductase (NADPH)
notes: GENE_ASSOCIATION: (7296.3) or (7296.1) or (7296.4) or (7296.2) SUBSYSTEM: Nucleotide interconversion EC Number: 1.8.1.9 Confidence Level: 4 AUTHORS: PMID:8577704,PMID:8999974 NOTES:
is version of: ECO:0000269
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8999974
fast: false
is: SBO:0000176
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.8.1.9
is described by: http://identifiers.org/pubmed/8577704

http://identifiers.org/biomodels.db/MODEL1109130000#_2b61e31c_9b4c_4ae7_9821_11548122146a
units: dimensionless
value: 0.0
type: LocalParameter

metaM prostgi2 e
type: Species
is: CHEBI:57403
name: prostaglandin I2(1-)
notes: FORMULA: C20H31O5 CHARGE: -1 INCHI: InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/p-1/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 EHMN_ABBREVIATION: C01312
constant: false
boundary condition: false
has only substance units: false
is: HMDB01335
initial amount: NaN
is: SBO:0000247
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_2e3ff9b8_2023_4eee_90f0_6b7a963c6c65
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1928214a_ba03_4c17_bb39_dc3420048dfe
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ec515bdf_0a53_42ee_a828_42e4d4c3d06c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_67c743a9_9441_4207_b242_327a10fecef6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1e62c489_33c0_4840_811d_f432591a1907
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cf7fdc91_9288_4983_bf01_66ae6c714c31
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d0b22c4d_c8c0_41fd_ace3_d794cd384ce1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a24769a_5fcc_4ea9_8dd1_b943a99db433
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_188927d3_8148_491e_a085_e9a1f825b966
is: SBO:0000297
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
initial concentration: NaN
has only substance units: false
is encoded by: hsa:516
has part: Q6FIH7
type: Species
boundary condition: true
initial amount: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#b94f04fe_d814_4933_a3a5_27518adced3f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9143e58e_3a5e_44f4_ab50_db7a3cd53bcf
value: 0.0
type: LocalParameter

metaR RE1835M
is described by: http://identifiers.org/pubmed/11454857
is described by: http://identifiers.org/pubmed/10817395
is: SBO:0000176
reactant: MODEL1109130000#
fast: false
modifier: MODEL1109130000#
reversible: true
name: RE1835
is described by: http://identifiers.org/pubmed/10944470
is described by: http://identifiers.org/pubmed/11673457
notes: GENE_ASSOCIATION: (10965.1) or (11332.1) SUBSYSTEM: Bile acid synthesis EC Number: 3.1.2.2 Confidence Level: 0 AUTHORS: PMID:10817395,PMID:10944470,PMID:11454857,PMID:11673457 NOTES: IT - fixed proton
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.1.2.2
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#b56b1385_6d29_4f1f_984c_d1a4079011e8
value: 0.0
type: LocalParameter

metaR r0295
notes: GENE_ASSOCIATION: 6576.1 SUBSYSTEM: Glycine, serine, alanine and threonine metabolism EC Number: 2.1.2.10 Confidence Level: 0 AUTHORS: PMID:7916605 NOTES:
fast: false
reversible: false
name: glycine synthase Nitrogen metabolism EC:2.1.2.10
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7916605
is version of: http://identifiers.org/ec-code/2.1.2.10

metaR GASNASEly
reversible: false
name: glycosylasparaginase, lysosomal
is version of: http://identifiers.org/ec-code/3.5.1.26
type: Reaction
is version of: ECO:0000000
modifier: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 175.1 SUBSYSTEM: N-glycan degradation EC Number: 3.5.1.26 Confidence Level: 0 AUTHORS: NOTES: NCD
reactant: MODEL1109130000#
is: SBO:0000176
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_1d2b614d_806b_4d9c_bb30_0689ee8e5c45
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9df3e7fc_ca58_422e_97f2_b89957b70d41
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e50dcd7b_a1c6_49bf_ae86_e146e895e2fc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_22ba9af1_f414_4c8e_8af3_81ba10f3ef23
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_96519071_e5a5_47fd_a236_8a05b7cb4405
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a54fda1b_3606_49c4_9f4e_4ba2da930f0b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_89a2b058_2560_48f9_823b_e96c2f844039
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6f03bfd5_815d_4d7a_b7aa_2d938d79a8b5
value: 0.0
type: LocalParameter

metaR RTOT4
notes: GENE_ASSOCIATION: SUBSYSTEM: R group synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: User defined, tissue specific fluxes that can be customized w/ various ratios of R1 through R5 NJ
fast: false
reactant: MODEL1109130000#
is version of: ECO:0000000
product: MODEL1109130000#
reversible: false
type: Reaction
is: SBO:0000176
name: R total flux

metaR EX HC01943 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Prothrombin exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_25904583_791b_4493_9509_c46639cab9ce
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b070d85_b224_4e93_92ae_21cd1ba21351
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1cf9f62d_7e6d_4f07_9c5a_3d6ab0490ffb
value: 1000.0
type: LocalParameter

metaR ACCOAC
modifier: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: EC Number: NOTES: GENE_ASSOCIATION: (31.1 and 32.1)
name: acetyl-CoA carboxylase
type: Reaction
reversible: false
is: SBO:0000176
fast: false
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_24ae6679_b240_44a8_a469_9a442f4654de
value: 1000.0
type: LocalParameter

metaR RTOT5
reversible: false
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
type: Reaction
is: SBO:0000176
name: R total flux
notes: GENE_ASSOCIATION: SUBSYSTEM: R group synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: User defined, tissue specific fluxes that can be customized w/ various ratios of R1 through R5 NJ
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_459f4488_0efc_45de_815a_7ebd50240646
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE1099L
is described by: http://identifiers.org/pubmed/1606923
product: MODEL1109130000#
is: SBO:0000176
modifier: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.1.6.2
is described by: http://identifiers.org/pubmed/10049998
notes: GENE_ASSOCIATION: 412.1 SUBSYSTEM: Steroid metabolism EC Number: 3.1.6.2 Confidence Level: 0 AUTHORS: PMID:10049998,PMID:1606923 NOTES:
fast: false
reversible: true
name: RE1099

metaM CE5653 c
initial concentration: 1.0
notes: FORMULA: C20H25O3 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5653
boundary condition: false
initial amount: NaN
name: 4-oxo-9-cis-retinoate
type: Species
has only substance units: false
is: SBO:0000247
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#f7ab27b6_0a5e_456b_8d3e_492bdef01e4c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_63f2b67e_9452_4d22_a9fe_2795ad7fbcb3
name: RRM1
initial amount: NaN
initial concentration: NaN
notes: DRUGBANK_INHIBITOR: DB00242, DB00441, DB00631, DB01005, DB01073
boundary condition: true
has only substance units: false
is: SBO:0000252
is: P23921
type: Species
constant: false
is encoded by: hsa:6240

metaM CE5114 c
constant: false
boundary condition: false
has only substance units: false
initial amount: NaN
notes: FORMULA: C41H62N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5114
type: Species
initial concentration: 1.0
is: SBO:0000247
name: trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA

metaR RTOT6
product: MODEL1109130000#
fast: false
reversible: false
name: R total flux
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: R group synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: User defined, tissue specific fluxes that can be customized w/ various ratios of R1 through R6 NJ
is version of: ECO:0000000
reactant: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_9985d40c_fbc0_44b1_812f_72a93137c828
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1d54f063_ef80_4d82_8f0d_4117d1fc0bc1
name: ALDOB
is encoded by: hsa:229
initial amount: NaN
type: Species
initial concentration: NaN
is: SBO:0000252
boundary condition: true
is: P05062
constant: true
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_31d4f3fa_5199_4a9b_b3c1_4a76e911774b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6eff7786_f8c5_4da1_bdea_aa412a22cdae
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c9394575_6707_483d_9199_49f4d9db5423
value: -1000.0
type: LocalParameter

metaR r0707
type: Reaction
reversible: true
is described by: http://identifiers.org/pubmed/1730777
is version of: http://identifiers.org/ec-code/3.1.3.1
is: SBO:0000176
name: 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate phosphohydrolase (alkaline optimum) Folate biosynthesis EC:3.1.3.1
reactant: MODEL1109130000#
fast: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 1629.1 SUBSYSTEM: Unassigned EC Number: 3.1.3.1 Confidence Level: 0 AUTHORS: PMID:1730777 NOTES:
product: MODEL1109130000#

metaR HPDCACRNCPT2
is described by: http://identifiers.org/pubmed/1528846
name: heptadecanoate transport into the mitochondria
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11274214
type: Reaction
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: PMID:11274214,PMID:1528846,PMID:1988962 NOTES: NJ
is: SBO:0000176
product: MODEL1109130000#
is version of: ECO:0000000
modifier: MODEL1109130000#
fast: false
reversible: false
is described by: http://identifiers.org/pubmed/1988962

http://identifiers.org/biomodels.db/MODEL1109130000#_054a038a_96fa_4c0f_ab93_85b63ed2a315
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_398b6c53_95f4_44f4_9769_1d1eef103097
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed03f688_2a59_4752_940d_96c45eef3a6f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33252256_972c_4713_9d0e_49f660f3bfa4
value: 1000.0
type: LocalParameter

metaR ENGASE2ly
reversible: false
is version of: http://identifiers.org/ec-code/3.2.1.96
product: MODEL1109130000#
fast: false
name: endo-beta-N-acetylglucosaminidase, lysosomal
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: N-glycan degradation EC Number: 3.2.1.96 Confidence Level: 0 AUTHORS: NOTES: NCD
type: Reaction
is: SBO:0000176
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_642596c5_5541_426f_9462_dba9c80e7c38
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9877aa1c_178b_4138_b894_de03ac4722b7
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0708
notes: GENE_ASSOCIATION: (1892.1) or (1962.1) or (3030.1) SUBSYSTEM: Tetrahydrobiopterin metabolism EC Number: 3.5.4.16 Confidence Level: 0 AUTHORS: PMID:10727395 NOTES:
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10727395
name: 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16
fast: false
reversible: true
is: SBO:0000176
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.5.4.16
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#acc49a0f_b676_4e17_ae72_d65ac87f6885
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_693d10e4_e1cf_4881_a4c4_267b3538fb8c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c8b98834_88d1_4f1f_931a_6e263180f3e4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d3d75dbc_07bd_42d8_a713_aa123eb02695
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX leuktrE4 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: leukotriene E4 exchange
type: Reaction

metaR FADH2tru
type: Reaction
is: SBO:0000185
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 1 AUTHORS: NOTES: diffusion - but unidirectional uptake into ER (to avoid loops w/ NAD/NADP) NJ
is version of: ECO:0000000
name: FADH2 transporter, endoplasmic reticulum
reversible: false
fast: false
product: MODEL1109130000#

metaR r0709
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.5.4.16
reversible: true
is: SBO:0000176
is described by: http://identifiers.org/pubmed/10727395
reactant: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: (1892.1) or (1962.1) or (3030.1) SUBSYSTEM: Tetrahydrobiopterin metabolism EC Number: 3.5.4.16 Confidence Level: 0 AUTHORS: PMID:10727395 NOTES:
name: r0709
type: Reaction
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_051b8197_fb82_47f7_be46_f643e7483fee
value: 0.0
type: LocalParameter

metaM prostgi2 c
is: HMDB01335
type: Species
constant: false
is: SBO:0000247
name: prostaglandin I2(1-)
initial amount: NaN
has only substance units: false
notes: FORMULA: C20H31O5 CHARGE: -1 INCHI: InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/p-1/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 EHMN_ABBREVIATION: C01312
initial concentration: 1.0
is: CHEBI:57403
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_57f62368_6a79_42af_8f0f_c2370f492d0d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1ed18878_0b3e_4751_b137_505a017a628e
units: dimensionless
value: 0.0
type: LocalParameter

metaR CSPG Ct
is: SBO:0000185
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES:
fast: false
reversible: false
reactant: MODEL1109130000#
name: chondroitin sulfate C transport, golgi to extracellular
is version of: ECO:0000000
type: Reaction

metaR RE1099G
notes: GENE_ASSOCIATION: 412.1 SUBSYSTEM: Steroid metabolism EC Number: 3.1.6.2 Confidence Level: 0 AUTHORS: PMID:10049998,PMID:1606923 NOTES:
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/1606923
modifier: MODEL1109130000#
reversible: true
name: RE1099
is: SBO:0000176
type: Reaction
is version of: http://identifiers.org/ec-code/3.1.6.2
is described by: http://identifiers.org/pubmed/10049998
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_34211977_74f7_4bc5_a44f_cd1d9f6e1cc5
units: dimensionless
value: 0.0
type: LocalParameter

metaM 3m4hpga c
is: HMDB04061
is: C05583
type: Species
notes: FORMULA: C9H10O4 CHARGE: 0 INCHI: InChI=1/C9H10O4/c1-13-9-4-6(8(12)5-10)2-3-7(9)11/h2-5,8,11-12H,1H3 HEPATONET_1.0_ABBREVIATION: HC01520 EHMN_ABBREVIATION: C05583
constant: false
name: 3-Methoxy-4-hydroxyphenylglycolaldehyde
boundary condition: false
is: http://identifiers.org/pubchem.substance/7909
has only substance units: false
initial concentration: 1.0
is: SBO:0000247
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#c4a53429_7301_441d_8665_8f8c51772b35
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_28f91321_5174_413f_b2b2_5f2856a0f6b8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d735f886_3149_4a59_b46f_db09b0e1ea79
value: -1000.0
type: LocalParameter

metaM 5forthf c
notes: FORMULA: C20H22N8O6 CHARGE: -2 HEPATONET_1.0_ABBREVIATION: HC00483 EHMN_ABBREVIATION: C00664 INCHI: InChI=1S/C20H24N8O6/c21-9-28-12(8-24-16-15(28)18(32)27-20(22)26-16)7-23-11-3-1-10(2-4-11)17(31)25-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,21,23H,5-8H2,(H,25,31)(H,29,30)(H,33,34)(H4,22,24,26,27,32)/p-2/t12-,13-/m0/s1
is: C00664
type: Species
name: 5-Formiminotetrahydrofolate
is: SBO:0000247
initial amount: NaN
initial concentration: 1.0
boundary condition: false
constant: false
has only substance units: false
is: HMDB01534
is: CHEBI:57456

http://identifiers.org/biomodels.db/MODEL1109130000#_062a4ac7_16f6_456e_be34_919e09318bc7
value: -1000.0
type: LocalParameter

metaR SAMHISTA
is version of: http://identifiers.org/ec-code/2.1.1.8
notes: GENE_ASSOCIATION: 3176.1 SUBSYSTEM: Histidine metabolism EC Number: 2.1.1.8 Confidence Level: 4 AUTHORS: PMID:7943261 NOTES: SAB R02155
product: MODEL1109130000#
name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7943261
is version of: ECO:0000269
fast: false
reversible: false
type: Reaction
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_b06bb454_3dcd_4a0f_9ede_84c0c5ebcd47
is: Q3KQV9
type: Species
is encoded by: hsa:91373
initial amount: NaN
has only substance units: false
constant: false
initial concentration: NaN
name: UAP1L1
is: SBO:0000252
boundary condition: true

metaR RN0001R
product: MODEL1109130000#
reactant: MODEL1109130000#
reversible: false
is version of: http://identifiers.org/ec-code/1.14.13.8
name: RN0001
is: SBO:0000176
notes: GENE_ASSOCIATION: (2329.1) or (2328.1) or (2330.1) or (2326.1) or (2327.1) SUBSYSTEM: Selenoamino acid metabolism EC Number: 1.14.13.8 Confidence Level: 0 AUTHORS: NOTES:
type: Reaction
modifier: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_794b19fd_d734_42a9_8c6e_0d57fa64d0aa
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ab881e55_4b2d_4565_8756_96b5356164db
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_49750170_5363_4613_90bf_2f0b6a538eeb
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_68a3a309_a170_457c_b88c_424698e5aa5e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1f336331_0f9f_4622_ba3e_0dfc61b2371d
value: 0.0
type: LocalParameter

metaR SPH1Ptr
name: sph1p intracellular transport
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 2 AUTHORS: PMID:15052333,PMID:15585321 NOTES: unknown mechanism for transport, may be vesicular/caveolar/other ... intracellular transport and extracellular export mechanisms must exist - see for example: PMID: 15585321 NJ
type: Reaction
is version of: ECO:0000000
reversible: true
is: SBO:0000185
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15052333
is described by: http://identifiers.org/pubmed/15585321

http://identifiers.org/biomodels.db/MODEL1109130000#_30b96ff4_7f4b_4f36_85e7_d9a85052a4eb
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ca69d3a0_b333_41a8_b65b_82531a4a4c01
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4e394745_08e3_4852_8dac_1ce0e2f2322f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f7b5c530_18e6_49b8_97c7_634a5ec74537
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f8733955_30b8_4304_b376_8e4ab1e0b36f
value: 1000.0
type: LocalParameter

metaM cgly c
has only substance units: false
constant: false
name: L-cysteinylglycine
is: CHEBI:4047
initial amount: NaN
boundary condition: false
is: SBO:0000247
notes: FORMULA: C5H10N2O3S CHARGE: 0 INCHI: InChI=1S/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9)/t3-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00784 EHMN_ABBREVIATION: C01419
initial concentration: 1.0
type: Species
is: HMDB00078

metaR S23T2g
type: Reaction
is described by: http://identifiers.org/pubmed/10504389
reactant: MODEL1109130000#
modifier: MODEL1109130000#
reversible: false
is version of: ECO:0000000
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.4.99.4
fast: false
is described by: http://identifiers.org/pubmed/8027041
is described by: http://identifiers.org/pubmed/8920913
is described by: http://identifiers.org/pubmed/8288606
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (6484.1) or (6482.1) or (6483.1) or (6482.2) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.99.4 Confidence Level: 4 AUTHORS: PMID:10504389,PMID:7901202,PMID:8027041,PMID:8288606,PMID:8920913 NOTES: NCD
is described by: http://identifiers.org/pubmed/7901202
name: beta-galactoside alpha-2,3-sialyltransferase (core 2)

metaR DM gpi sig er
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 0 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: false
name: DM gpi sig(er)
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#b626b28f_dbc5_4699_9531_001eead99709
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74143ea5_a488_4ff8_8427_6aac4dcd56cb
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#de978477_39c5_40ed_8011_f5ca26493a53
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_abf9f84f_0886_4881_b03e_f435f9ac6f74
name: MGST1
has only substance units: false
is: SBO:0000252
initial concentration: NaN
is encoded by: hsa:4257
constant: false
is: P10620
type: Species
boundary condition: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_9f891bc8_4242_41b6_96c7_9fecb6df7ac1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_87f71aba_15f1_4c4e_b01a_6c7dba494aea
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1e179d3c_c128_4db6_add4_28c67c91fa1b
value: 0.0
type: LocalParameter

metaR RE1099C
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/1606923
is described by: http://identifiers.org/pubmed/10049998
type: Reaction
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.1.6.2
fast: false
reversible: true
name: RE1099
notes: GENE_ASSOCIATION: 412.1 SUBSYSTEM: Steroid metabolism EC Number: 3.1.6.2 Confidence Level: 0 AUTHORS: PMID:10049998,PMID:1606923 NOTES:
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_7dcf6125_49a6_443c_8944_a3ec2e1aef2e
value: -1000.0
type: LocalParameter

metaR RE1835X
is described by: http://identifiers.org/pubmed/11673457
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.1.2.2
is described by: http://identifiers.org/pubmed/10944470
reversible: true
is described by: http://identifiers.org/pubmed/10817395
type: Reaction
is described by: http://identifiers.org/pubmed/11454857
is: SBO:0000176
notes: GENE_ASSOCIATION: (10005.1) or (122970.1) or (570.1) SUBSYSTEM: Bile acid synthesis EC Number: 3.1.2.2 Confidence Level: 0 AUTHORS: PMID:10817395,PMID:10944470,PMID:11454857,PMID:11673457 NOTES: IT - fixed proton
name: RE1835
modifier: MODEL1109130000#
product: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#a6d97d4d_7732_4d73_927a_7e52cf3836f6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f0e730c2_27d2_4ee8_a2bb_dbab37316960
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6dbda8af_920d_4321_9f10_705a62a81624
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_590893fa_6fd3_4685_9edb_a33f573e5b9d
value: 1000.0
type: LocalParameter

metaR HPDCACRNCPT1
is described by: http://identifiers.org/pubmed/1988962
name: carnitine fatty-acyl transferase
is version of: http://identifiers.org/ec-code/2.3.1.21
is version of: ECO:0000000
modifier: MODEL1109130000#
type: Reaction
fast: false
reactant: MODEL1109130000#
is: SBO:0000176
reversible: false
notes: GENE_ASSOCIATION: (1375.2) or (1375.3) or (1374.1) or (126129.1) or (1375.1) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: PMID:1988962 NOTES: NJ
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#b5482d53_e934_44a2_af71_74a8fa1b9f08
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e0267098_0672_4d33_a8fc_b2ce33dcf058
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_575557f0_f5a9_48dd_8bde_9e166bc92744
type: Species
boundary condition: true
initial concentration: NaN
is encoded by: hsa:5152
is: SBO:0000252
has only substance units: false
name: PDE9A
constant: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_123ae8b8_a57f_4080_aa43_c8cb40e8e490
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_731c66ac_5904_4dd3_a717_de83a31a4404
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_15296975_0546_4162_9026_e1690b17c1f8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d0df34a7_766c_4636_aeae_93238272ee15
units: dimensionless
value: 0.0
type: LocalParameter

metaR FAOXOHMC10DC10c
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: doi:10.1016/j.physletb.2003.10.071 EC Number: NOTES: The extra one proton was obtained in the product, from the aldehyde form of the omega-hydroxy decanoic acid (i.e. An intermediate not shown in this reaction). This was done in-order to balance the reaction and also to obtain the dicarboxylic form of the decanoic acid. GENE_ASSOCIATION: (128.1 and 224.1)
is: SBO:0000176
reactant: MODEL1109130000#
fast: false
modifier: MODEL1109130000#
reversible: false
product: MODEL1109130000#
type: Reaction
name: fatty acid omega oxidation(w-OHMC10-->DC10)c

http://identifiers.org/biomodels.db/MODEL1109130000#_8a596fcc_f15c_4302_ae23_be34751b43d0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ae210c83_fe34_4770_a3ff_5341c4d46e85
name: NDUFA2
has only substance units: false
is: O43678
is encoded by: hsa:4695
type: Species
is: SBO:0000252
constant: true
boundary condition: true
initial amount: NaN
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#ab9ecd6d_a89b_46c8_84af_730da973ba93
value: -1000.0
type: LocalParameter

metaR RE1538X
name: RE1538
is: SBO:0000176
is described by: http://identifiers.org/pubmed/11454677
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 196743.1 SUBSYSTEM: Urea cycle EC Number: 1.5.3.11 Confidence Level: 0 AUTHORS: PMID:11454677,PMID:9359869 NOTES:
type: Reaction
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9359869
reversible: false
is version of: http://identifiers.org/ec-code/1.5.3.11
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#e4591a35_25d3_47f4_bd14_411df6fcf44f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aa9017c4_ebe8_4340_a77c_4558b67ca5ec
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4639d863_9711_4f26_86a0_9b623fb8d542
value: 1000.0
type: LocalParameter

metaM C14849 x
name: Benzo[a]pyrene-9,10-oxide
is: SBO:0000247
constant: false
boundary condition: false
type: Species
has only substance units: false
initial amount: NaN
is: C14849
notes: FORMULA: C20H12O CHARGE: 0 INCHI: InChI=1/C20H12O/c1-2-11-4-5-13-10-14-7-9-16-20(21-16)19(14)15-8-6-12(3-1)17(11)18(13)15/h1-10,16,20H EHMN_ABBREVIATION: C14849
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_86101874_093c_4ef1_b1b5_c7c28e0277b2
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c59799ce_7100_4f6a_be68_55ee3ce66dc6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a489b8a7_7625_4ebc_803e_3028a789cf8c
is: SBO:0000252
is encoded by: hsa:6480
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ST6GAL1
type: Species
constant: true
boundary condition: true
is: P15907

http://identifiers.org/biomodels.db/MODEL1109130000#bc04b037_aad3_4cd5_aa28_ff56ecb1fa4d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_719ff73c_e6d8_4375_9dd7_cf04bfd355b1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_67a15846_4300_4d6d_a84f_2cddef5f9882
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b05ebef9_6cd9_4ab2_bc54_5bd69635754b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9e655a90_001b_4e84_9a70_d022db55582a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#da3baa17_9658_4a58_b376_f946fb8d6eea
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_64f586af_267e_4a61_a677_974f6348e052
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33f14bde_b632_456b_9644_8c461a390891
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_08bbd444_cc0b_4c10_837a_79ade35c3dff
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_68e6c4b2_d07c_4997_bc80_354b03fbcae2
has only substance units: false
initial amount: NaN
is encoded by: hsa:645740
constant: false
type: Species
initial concentration: NaN
is: SBO:0000252
boundary condition: true
name: _645740_1_c

metaR FAOXOHC16C16DCc
product: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
name: fatty acid omega oxidation(w-OHC16-->C16DC)c
is described by: http://identifiers.org/pubmed/15060085
reversible: false
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 3 AUTHORS: PMID:15060085,PMCID:PMC1152672 EC Number: NOTES: undergoes series of beta oxidation cycles to generate C8DC,C6DC,C4DC and acetate. The extra one proton was obtained in the product, from the aldehyde form of the omega-hydroxy palmitic acid (i.e. An intermediate not shown in this reaction). This was done in-order to balance the reaction and also to obtain the dicarboxylic form of the palmitic acid. GENE_ASSOCIATION: (128.1 and 224.1)
is: SBO:0000176
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6409827b_63b4_4feb_b5a1_acb4862992e2
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7c494e00_113f_4655_8a52_b19b5e6ddfce
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b22625b2_56e7_4347_98f4_ebab1bff09ca
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_45ac670f_42e2_45b6_9875_d6b9b2daf4fa
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5509a1a1_ffca_4102_9568_dc7e532231fd
name: TGDS
type: Species
initial amount: NaN
is: Q05DQ3
constant: true
has only substance units: false
is encoded by: hsa:23483
is: SBO:0000252
boundary condition: true
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_2942c537_66ab_4a8b_87c6_e7b4b8188ac5
value: -1000.0
type: LocalParameter

metaR HSD3B12r
fast: false
product: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction
is version of: ECO:0000134
is described by: http://identifiers.org/pubmed/12832414
notes: GENE_ASSOCIATION: 3284.1 SUBSYSTEM: Steroid metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:12832414 NOTES: kinetic studies done with recombinant human cDNA transfected into baculovirus
is: SBO:0000176
reactant: MODEL1109130000#
name: 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_485ea3f4_a3a9_4ccb_9d39_2c7e2e393071
value: 1000.0
type: LocalParameter

metaR RE1836C
name: RE1836
type: Reaction
product: MODEL1109130000#
reversible: true
is version of: http://identifiers.org/ec-code/2.3.1.154
is described by: http://identifiers.org/pubmed/10706581
is: SBO:0000176
fast: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Bile acid synthesis EC Number: 2.3.1.154 Confidence Level: 0 AUTHORS: PMID:10706581 NOTES:

metaM dec24dicoa m
initial amount: NaN
notes: FORMULA: C31H46N7O17P3S CHARGE: -4
name: 2,4-decadienoylcoa
initial concentration: 1.0
has only substance units: false
is: HMDB01168
is: SBO:0000247
type: Species
constant: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_232c52f1_b985_4af8_af5c_7dd4b9c737e9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_92f9a822_3662_4512_a0d2_7126257eb445
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ef77dcf8_6aeb_468f_97d8_dc13d231b635
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bd0534bb_c94c_4c1b_b058_2569572a859a
value: 0.0
type: LocalParameter

metaR FUMSO3tm
is: SBO:0000185
fast: false
is described by: http://identifiers.org/pubmed/14598172
type: Reaction
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 1468.1 SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 4 AUTHORS: PMID:14598172,PMID:4441366 NOTES: MM
product: MODEL1109130000#
reversible: true
is version of: ECO:0000269
reactant: MODEL1109130000#
name: Fumarate:sulfite antiport, mitochondrial
is described by: http://identifiers.org/pubmed/4441366

http://identifiers.org/biomodels.db/MODEL1109130000#_5ba3e007_89c4_4d6e_ab11_7791a6f9bbb7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8e10e8f1_2586_4b77_b517_a418b733477e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dbc0159b_1853_485f_8eb3_475090990673
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_63c94341_e892_4993_8e4c_6c9935db03d1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_60499721_9d27_4a60_95dd_ea0b65ad68d1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_483e12a0_6197_4c7c_867f_81be8611799c
value: -1000.0
type: LocalParameter

metaR GPIAT
type: Reaction
notes: GENE_ASSOCIATION: 284098.1 SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:14517336 NOTES: EC 2.3.-.- NCD
is: SBO:0000176
reactant: MODEL1109130000#
name: glucosaminylphosphatidyl inositol acetyltransferase
is version of: ECO:0000269
modifier: MODEL1109130000#
reversible: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14517336
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_0a5384da_acba_4d92_9205_b1a630cb953b
value: -1000.0
type: LocalParameter

metaM gthox e
is: CHEBI:58297
initial concentration: 1.0
type: Species
is: SBO:0000247
boundary condition: false
is: HMDB03337
notes: FORMULA: C20H30N6O12S2 CHARGE: -2 INCHI: InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/p-2/t9-,10-,11-,12-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00125 EHMN_ABBREVIATION: C00127
constant: false
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_7c4bf4e8_c8f5_423f_b27f_5ea72dfda3cd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_535050d3_3c08_4e58_bd2d_2e4b6de57500
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_92f88c7e_548b_4a51_9663_961dd31855f5
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX pan4p LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for pan4p
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_0e95e1bc_51e6_4f15_840a_126d54fa3d6f
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_731e6bf2_0792_4055_88d9_a373457fa3b8
is: SBO:0000297
initial amount: NaN
constant: false
initial concentration: NaN
has only substance units: false
has part: B7Z3U6
boundary condition: true
name: ATP1A1:ATP1B3
is encoded by: hsa:483
is encoded by: hsa:476
has part: P54709
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_7f36d6d1_41c7_4388_9de6_e0fd1026c165
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

metaM CE5240 x
is: SBO:0000247
boundary condition: false
name: 2-hydroxyestrone-4-S-glutathione
has only substance units: false
initial amount: NaN
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5240
type: Species
initial concentration: 1.0
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#e3aff4f3_766c_485b_be5a_3f6d7eb1ce2b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f87534a_541b_4e60_b86d_efbf4f2485d0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_77a90d66_40d1_4a52_8c9f_8dbe9e6a3a43
type: Species
is encoded by: hsa:5352
is: SBO:0000252
boundary condition: true
is: O00469
name: PLOD2
has only substance units: false
initial concentration: NaN
constant: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_8c63f419_9bf9_4f5c_b8b6_fd591ab5de96
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3075b483_99a1_477e_b938_498d9a3ff2e0
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX HC01942 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Plasminogen exchange
type: Reaction

metaM CE5726 c
is: SBO:0000247
type: Species
boundary condition: false
constant: false
has only substance units: false
name: Prostaglandin PGE2 1-glyceryl ester
notes: FORMULA: C23H38O7 CHARGE: 0 INCHI: EHMN_ABBREVIATION: CE5726
initial amount: NaN
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_metaM_acglc13galacglcgal14acglcgalgluside_hs_g
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247
constant: false
has only substance units: false
notes: FORMULA: C66H115N4O37FULLRCO CHARGE: 0 INCHI:
name: nLc7Cer
type: Species
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3430dcea_18b1_4c27_996e_b3bb63a639b6
value: 0.0
type: LocalParameter

metaR B3GALT43g
name: Beta-1,3-galactosyltransferase 4
is: SBO:0000176
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 8705.1 SUBSYSTEM: Sphingolipid metabolism EC Number: 2.4.1.62 Confidence Level: 4 AUTHORS: NOTES: NJ
is version of: ECO:0000269
reactant: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.62
type: Reaction

metaM gthox c
name: Oxidized glutathione
constant: false
notes: FORMULA: C20H30N6O12S2 CHARGE: -2 HEPATONET_1.0_ABBREVIATION: HC00125 EHMN_ABBREVIATION: C00127 INCHI: InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/p-2/t9-,10-,11-,12-/m0/s1
initial amount: NaN
initial concentration: 1.0
is: CHEBI:58297
type: Species
boundary condition: false
is: SBO:0000247
is: C00127
has only substance units: false
is: HMDB03337

http://identifiers.org/biomodels.db/MODEL1109130000#_499e03a3_09fb_4dc9_8904_bbcc1f3bf877
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ede57061_9e35_4aa6_a145_2ce548d5d64b
type: Species
constant: true
initial concentration: NaN
initial amount: NaN
has only substance units: false
is: Q86Y39
is: SBO:0000252
boundary condition: true
is encoded by: hsa:126328
name: NDUFA11

http://identifiers.org/biomodels.db/MODEL1109130000#_9cb835c0_7002_45d0_8ee7_bd48d3a72f8e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_81a9a785_48de_4c68_a458_334e22741a6b
has only substance units: false
name: TRDMT1
initial amount: NaN
constant: false
type: Species
is: SBO:0000252
initial concentration: NaN
boundary condition: true
is encoded by: hsa:1787

http://identifiers.org/biomodels.db/MODEL1109130000#_a8e29161_6d10_4130_882e_6dcd728a89a6
initial amount: NaN
type: Species
constant: true
is: P00352
name: ALDH1A1
initial concentration: NaN
has only substance units: false
is encoded by: hsa:216
is: SBO:0000252
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_20fbac28_31b2_47db_ac13_f1780e3f49c4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_459d5b73_2c95_4527_8918_617cb694c533
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e012e3a6_3487_4f8c_8288_4dae70cdafd6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_379d1408_03ab_41b7_84b6_35d4961d5d2b
value: 1000.0
type: LocalParameter

metaM CE5240 m
type: Species
initial concentration: 1.0
boundary condition: false
constant: false
initial amount: NaN
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5240
name: 2-hydroxyestrone-4-S-glutathione
is: SBO:0000247
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_e3e61239_a125_43db_ab46_286deaf72abb
initial amount: NaN
boundary condition: true
notes: DRUGBANK_UNKNOWN: DB00157, DB01907, DB02205, DB03331, DB04477
is encoded by: hsa:26330
is: O14556
name: GAPDHS
has only substance units: false
is: SBO:0000252
initial concentration: NaN
constant: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#c16c33b7_c342_4a20_a816_2156dfe88405
value: 0.0
type: LocalParameter

metaR RE1836M
reactant: MODEL1109130000#
is: SBO:0000176
fast: false
reversible: true
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 6342.1 SUBSYSTEM: Bile acid synthesis EC Number: 2.3.1.154 Confidence Level: 0 AUTHORS: PMID:10706581 NOTES:
is version of: http://identifiers.org/ec-code/2.3.1.154
is described by: http://identifiers.org/pubmed/10706581
type: Reaction
product: MODEL1109130000#
name: RE1836

metaR SPH1Pte
reversible: true
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:15585321 NOTES: unknown mechanism for transport, may be vesicular/caveolar/other ... intracellular transport and extracellular export mechanisms must exist - see for example: PMID: 15585321 NJ
fast: false
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/15585321
name: sph1p transport
is: SBO:0000185
product: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#ac38ca05_27a7_4dc1_bb3b_5391f0becfdc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2b860916_1c76_4e52_9f9f_e676e1525f60
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_27983da1_63d8_4875_b6ce_598a8e3825d1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7bcdc0c5_55b8_4d82_ac6e_2b896d297a5e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24d233fb_f8b8_4586_bc8f_56cc4815cf0d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_02169cc9_a71e_4c75_b3af_ed518c9a5f54
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0489e8bc_7616_4b3c_a957_c11eba1b3017
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2dbbfe0a_a021_447a_96bb_2dcb6e513e73
boundary condition: true
name: HAS1
is: SBO:0000252
initial concentration: NaN
constant: false
initial amount: NaN
has only substance units: false
type: Species
is encoded by: hsa:3036
is: Q8IYH3

http://identifiers.org/biomodels.db/MODEL1109130000#_53db31dc_7e07_45b8_aa82_9f6e3d6c13d0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_e4d7aad0_aa76_48da_bb2e_3a88cf3b4e0c
initial amount: NaN
initial concentration: NaN
has only substance units: false
type: Species
is: SBO:0000252
constant: false
name: _728226_1_m
boundary condition: true
is encoded by: hsa:728226

http://identifiers.org/biomodels.db/MODEL1109130000#ace6d170_1cca_467e_96ec_517d9bfcccec
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bbbed45a_2241_4280_b600_6128498e370c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_50fc44a5_e6fa_4283_ba4f_04e3788e3ee6
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a0f9af3b_76ff_4468_89de_712f8095eec8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bb01d588_60c9_497d_b25d_69dd7a04369b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_05aeedf9_f80b_46d9_8017_dd5997f966d7
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8dae42c1_99c7_4276_a181_851b4499ecae
type: Species
is encoded by: hsa:85365
name: ALG2
constant: true
initial concentration: NaN
initial amount: NaN
has only substance units: false
is: SBO:0000252
boundary condition: true
is: Q9H553

metaR RE0512M
fast: false
is: SBO:0000176
product: MODEL1109130000#
reversible: true
is version of: http://identifiers.org/ec-code/1.1.1.35
type: Reaction
is described by: http://identifiers.org/pubmed/7846063
reactant: MODEL1109130000#
modifier: MODEL1109130000#
name: RE0512
notes: GENE_ASSOCIATION: (3030.1) or (3295.1) or (1962.1) or (3033.1) or (3028.1) or (3032.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:7846063 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#f1810223_47ca_42f3_bc79_087128e77b78
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b06bbf61_d03f_4648_8a84_f8a8a3805d77
units: dimensionless
value: 0.0
type: LocalParameter

metaR THFt2
fast: false
product: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/11375437
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770311
name: tetrahydrofolate transport via anion exchange
modifier: MODEL1109130000#
is version of: ECO:0000269
is: SBO:0000185
type: Reaction
notes: GENE_ASSOCIATION: (6573.1) or (6573.2) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:11375437,PMID:14770311 NOTES: IT

metaR r1368
is described by: http://identifiers.org/pubmed/8725559
fast: false
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1554704
reactant: MODEL1109130000#
name: Vesicular transport
is: SBO:0000185
is described by: http://identifiers.org/pubmed/18021224
is described by: http://identifiers.org/pubmed/8781017
is described by: http://identifiers.org/pubmed/11023036
is described by: http://identifiers.org/pubmed/12883891
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, lysosomal EC Number: Confidence Level: 0 AUTHORS: PMID:11023036,PMID:12739169,PMID:12856180,PMID:12883891,PMID:1554704,PMID:18021224,PMID:4553030,PMID:793184,PMID:8725559,PMID:8781017 NOTES:
is described by: http://identifiers.org/pubmed/4553030
is described by: http://identifiers.org/pubmed/12739169
is described by: http://identifiers.org/pubmed/793184
reversible: false
is described by: http://identifiers.org/pubmed/12856180

http://identifiers.org/biomodels.db/MODEL1109130000#fb394714_f73e_4843_941d_42a1f39ba21a
value: -1000.0
type: LocalParameter

metaR RE1539C
notes: GENE_ASSOCIATION: SUBSYSTEM: Urea cycle EC Number: 1.5.3.11 Confidence Level: 0 AUTHORS: PMID:11454677,PMID:9359869 NOTES:
is described by: http://identifiers.org/pubmed/9359869
product: MODEL1109130000#
name: RE1539
is version of: http://identifiers.org/ec-code/1.5.3.11
is described by: http://identifiers.org/pubmed/11454677
reactant: MODEL1109130000#
is: SBO:0000176
reversible: false
fast: false
type: Reaction

metaM CE2189 c
is: SBO:0000247
type: Species
notes: FORMULA: C19H24O3 CHARGE: 0 INCHI: InChI=1/C19H24O3/c1-19-10-9-12-11-5-7-16(20)18(22-2)14(11)4-3-13(12)15(19)6-8-17(19)21/h5,7,12-13,15,20H,3-4,6,8-10H2,1-2H3/t12-,13-,15+,19-/m1/s1 EHMN_ABBREVIATION: CE2189
initial concentration: 1.0
boundary condition: false
initial amount: NaN
has only substance units: false
constant: false
name: 4-methoxyestrone

http://identifiers.org/biomodels.db/MODEL1109130000#f3ad3e5e_c943_4f86_bb87_800a753831e7
value: 1000.0
type: LocalParameter

metaM prostgi2 r
initial amount: NaN
type: Species
name: prostaglandin I2(1-)
notes: FORMULA: C20H31O5 CHARGE: -1 INCHI: InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/p-1/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 EHMN_ABBREVIATION: C01312
constant: false
has only substance units: false
is: SBO:0000247
is: CHEBI:57403
boundary condition: false
initial concentration: 1.0
is: HMDB01335

http://identifiers.org/biomodels.db/MODEL1109130000#_56162944_a276_4b1e_8bf4_e1711309e560
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1dfd565f_6f73_4931_8664_f614d64d475c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d45629e4_0cdd_438e_ac42_47f9d199545b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_37de8135_a973_44fe_af86_468e4d4a2f5b
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5661 c
constant: false
is: SBO:0000247
initial amount: NaN
notes: FORMULA: C20H29O5 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5661
initial concentration: 1.0
boundary condition: false
has only substance units: false
type: Species
name: 15-oxo-lipoxin A4

http://identifiers.org/biomodels.db/MODEL1109130000#_115543d3_f547_4262_8daa_4f1e32d86351
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a76d18fc_bff9_450a_ba5a_a44360af0f08
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ec3afc48_0f43_4b87_8994_3ee27198799d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c06ff981_9276_452a_928d_26789a1b70b6
value: 1000.0
type: LocalParameter

metaR r1367
is described by: http://identifiers.org/pubmed/12883891
is described by: http://identifiers.org/pubmed/4553030
is described by: http://identifiers.org/pubmed/793184
name: Vesicular transport
is described by: http://identifiers.org/pubmed/12856180
is: SBO:0000185
is described by: http://identifiers.org/pubmed/11023036
type: Reaction
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, lysosomal EC Number: Confidence Level: 0 AUTHORS: PMID:11023036,PMID:12739169,PMID:12856180,PMID:12883891,PMID:1554704,PMID:18021224,PMID:4553030,PMID:793184,PMID:8725559,PMID:8781017 NOTES:
is described by: http://identifiers.org/pubmed/12739169
is described by: http://identifiers.org/pubmed/1554704
reversible: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8725559
is described by: http://identifiers.org/pubmed/18021224
fast: false
is described by: http://identifiers.org/pubmed/8781017

http://identifiers.org/biomodels.db/MODEL1109130000#_76a55bb4_edc2_4549_bef4_bbb823947833
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_67bbb1c0_035d_4508_95f5_f1fcbaa1ab47
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e164d2de_4650_4598_b3a2_fa7e42a066aa
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7e3e0e9c_7b70_41b4_bc75_607576c20e72
type: Species
initial concentration: NaN
has only substance units: false
is: SBO:0000252
name: ALDH4A1
boundary condition: true
is: P30038
is encoded by: hsa:8659
constant: false
notes: DRUGBANK_UNKNOWN: DB00157
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#b4cd8a84_97b0_4df5_b236_41be40972d3a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_922e540f_7ee2_4d62_9836_3d34e6d07baa
units: dimensionless
value: 0.0
type: LocalParameter

metaM gthox m
initial concentration: 1.0
type: Species
notes: FORMULA: C20H30N6O12S2 CHARGE: -2 INCHI: InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/p-2/t9-,10-,11-,12-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00125 EHMN_ABBREVIATION: C00127
is: HMDB03337
has only substance units: false
initial amount: NaN
is: SBO:0000247
is: CHEBI:58297
constant: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_b4775167_4105_47d0_b8e2_d2fb697ff7e0
is: Q9NUI1
initial concentration: NaN
constant: true
is: SBO:0000252
has only substance units: false
name: DECR2
is encoded by: hsa:26063
initial amount: NaN
boundary condition: true
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_22521003_5a1f_4858_94a0_59d789291b6a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_29a62f77_8b90_44d0_b353_59194dd6cf9b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8f99eb19_9f12_47ad_8212_973716394d3b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3ddaf2ab_203c_4dad_baed_fd1ec09d7fe8
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5240 r
has only substance units: false
is: SBO:0000247
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5240
boundary condition: false
type: Species
name: 2-hydroxyestrone-4-S-glutathione
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_8d77b534_99e3_424c_9dfa_07ed6dadd343
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#b94848e3_9de2_45ec_aa41_f59bd334a671
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_099aba7b_7fa3_4d1e_b4ce_098b74eedcc5
value: 1000.0
type: LocalParameter

metaM acmana r
is: CHEBI:17122
type: Species
constant: false
has only substance units: false
is: HMDB01129
name: N-acetyl-D-mannosamine
boundary condition: false
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C8H15NO6 CHARGE: 0 INCHI: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6-,7-,8-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00474 EHMN_ABBREVIATION: C00645

http://identifiers.org/biomodels.db/MODEL1109130000#c5a33ecd_5fe2_496c_8947_002102124f52
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d04fc909_98c8_4af7_911f_80148dd14261
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8ec40935_d2f0_4c6f_8f80_bb8c31843aa4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8512a483_3d60_4783_abe6_f859fe37e65e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6f95a4e7_a1ce_49cc_ad52_6c90fd907280
value: 1000.0
type: LocalParameter

metaR r1365
name: Vesicular transport
is described by: http://identifiers.org/pubmed/8781017
is described by: http://identifiers.org/pubmed/793184
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, lysosomal EC Number: Confidence Level: 0 AUTHORS: PMID:11023036,PMID:12739169,PMID:12856180,PMID:12883891,PMID:1554704,PMID:18021224,PMID:4553030,PMID:793184,PMID:8725559,PMID:8781017 NOTES:
is described by: http://identifiers.org/pubmed/4553030
type: Reaction
is: SBO:0000185
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
is described by: http://identifiers.org/pubmed/12856180
reversible: false
is described by: http://identifiers.org/pubmed/1554704
is described by: http://identifiers.org/pubmed/8725559
is described by: http://identifiers.org/pubmed/11023036
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/18021224
fast: false
is described by: http://identifiers.org/pubmed/12883891

http://identifiers.org/biomodels.db/MODEL1109130000#_26ec51bb_6a3b_4054_9627_4ec679913756
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18c8959d_b462_4bdd_87ce_a72cfd66a51f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0e01cb6b_bf30_4d89_a1e3_23b8063235e1
value: 0.0
type: LocalParameter

metaR RE3556C
product: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:234423 NOTES:
reversible: true
is described by: http://identifiers.org/pubmed/234423
name: RE3556
reactant: MODEL1109130000#
fast: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_5eff44ca_6584_4e14_af78_38217aa82ce0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b867b386_cb4f_49f4_bd2c_ddd6882d365b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a78ef1a8_1f58_48a3_861c_02af5c5d3d45
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8c2d1678_a459_4b5c_b5d0_50be78962d9b
notes: DRUGBANK_UNKNOWN: DB00144
is encoded by: hsa:8527
is: SBO:0000252
initial amount: NaN
boundary condition: true
is: Q16760
initial concentration: NaN
constant: false
type: Species
name: DGKD
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_0ebca931_8cea_4611_9f62_97a52b2a56c5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7d1ce23c_4efe_4b63_984e_a98ae696703d
value: 0.0
type: LocalParameter

metaR r1364
product: MODEL1109130000#
name: Vesicular transport
is described by: http://identifiers.org/pubmed/8725559
is described by: http://identifiers.org/pubmed/1554704
is described by: http://identifiers.org/pubmed/18021224
reversible: false
reactant: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/12856180
is described by: http://identifiers.org/pubmed/12883891
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, lysosomal EC Number: Confidence Level: 0 AUTHORS: PMID:11023036,PMID:12739169,PMID:12856180,PMID:12883891,PMID:1554704,PMID:18021224,PMID:4553030,PMID:793184,PMID:8725559,PMID:8781017 NOTES:
is described by: http://identifiers.org/pubmed/12739169
is described by: http://identifiers.org/pubmed/8781017
is described by: http://identifiers.org/pubmed/11023036
is described by: http://identifiers.org/pubmed/4553030
is described by: http://identifiers.org/pubmed/793184
fast: false
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_77a5e114_e301_4229_b05c_c883bce04d59
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_334a6a2c_09b9_4093_852f_3e9c2f83e2f8
type: Species
is: SBO:0000252
constant: false
is: Q6IZA2
initial amount: NaN
name: FUT1
has only substance units: false
boundary condition: true
is encoded by: hsa:2523
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#bd737b2d_8cca_4f5d_bd22_221193d0e372
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f400fcaf_84fd_4f9b_a7db_73139c34e36b
units: dimensionless
value: 0.0
type: LocalParameter

metaM docohepcoa m
type: Species
initial concentration: 1.0
constant: false
notes: FORMULA: C43H60N7O17P3S CHARGE: -4
is: SBO:0000247
initial amount: NaN
name: 2,4,7,10,13,16,19-docosaheptenoylcoa
has only substance units: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#ed7657e9_d1c4_426e_afe8_b1eb3eab3d4b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3f1187b8_257f_4998_b156_6c8067ed5c9d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ec69671c_dcc8_4e67_a258_470abfaf8a02
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_10f4cff2_136e_41e4_80aa_f6b94449fcf7
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: NDUFA11:NDUFS7:ND1:ND2:ND3:ND4:ND4L:ND5:ND6:NDUFA1:NDUFA2:NDUFA3:NDUFA4:NDUFA5:NDUFA6:NDUFA7:NDUFA8:NDUFA9:NDUFA10:NDUFAB1:NDUFB1:NDUFB2:NDUFB3:NDUFB4:NDUFB5:NDUFB6:NDUFB7:NDUFB8:NDUFB9:NDUFB10:NDUFC1:NDUFC2:NDUFS1:NDUFS2:NDUFS3:NDUFV1:NDUFS4:NDUFS5:NDUFS6:NDUFS8:NDUFV2:NDUFV3:NDUFA13:NDUFA12:TUSC3
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#bebd33e5_34db_4bce_a42f_06b665d0b01b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eec95391_a7ee_495e_b195_fb55788b117b
value: 0.0
type: LocalParameter

metaR EX 35cgmp LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: 3,5-Cyclic GMP exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_52a19684_5ff1_4fb9_a0d8_23a903c13054
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6211c204_d054_4ec1_bfd8_eab13cd4ffe6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be5d4af0_cbec_4e2f_950c_050d1b43858b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b5ed4f3e_e2b6_4e8b_90a0_81e24aa95e00
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fede80d7_1b88_472b_892e_128ccff6930e
value: -1000.0
type: LocalParameter

metaR RE3186M
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9819701
is version of: http://identifiers.org/ec-code/1.3.99.3
type: Reaction
reversible: true
is: SBO:0000176
modifier: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/10407780
notes: GENE_ASSOCIATION: (34.1) or (33.1) or (36.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.3.99.3 Confidence Level: 0 AUTHORS: PMID:10407780,PMID:9469587,PMID:9819701 NOTES:
name: RE3186
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9469587

http://identifiers.org/biomodels.db/MODEL1109130000#dfc55d20_23d9_4fc9_93f5_8482bff32798
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2a593559_aff2_408c_bf50_89fd0c824f9c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f01401f8_9686_45bd_a7cc_1960913ec283
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6b084e34_6583_4a8c_b578_7cbe9bf971c6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_60d5d0c5_02ee_48ae_88ae_52f69174db8a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c19feddd_70e5_4480_b6c9_447867727a7e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_26f8f815_a394_4f51_8858_757881e6cdfa
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_757ace6c_e87c_4c92_8770_f979a80bdcf5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a87bd96_3247_4008_be7b_da5ac2428087
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5de548f1_9318_46eb_906d_792ac11235f6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8c07d72b_97f0_497d_a873_93d533d01ef4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0117704d_2ee6_469f_abff_7e0463469cd9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_42c1f677_090a_424a_a0dc_15e773f88a5b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_40b7e639_e5bb_4cff_a744_f353f8d79dfb
initial concentration: NaN
is: SBO:0000252
name: TREH
is encoded by: hsa:11181
is: O43280
type: Species
initial amount: NaN
constant: true
has only substance units: false
boundary condition: true

metaR PCHOLHSTDe
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 2 AUTHORS: Sareen S. Gropper, jack L. Smith, James L. Groff (2009) Wadaworth cengage learning, Advanced nutrition and human metabolism, 5th edition, page 142-148. EC Number: NOTES: transported in chylomicrons into lymph GENE_ASSOCIATION:
is: SBO:0000185
fast: false
reversible: false
name: PCHOLHSTDe
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_517c7f80_d95c_4544_be41_be2ed1858bee
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_75485da8_f64a_41ac_9d7b_2bbe9293ef09
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE3557C
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9755286
name: RE3557
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: 2.5.1.18 Confidence Level: 0 AUTHORS: PMID:9755286 NOTES:
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.5.1.18
fast: false
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_fe7641b2_a032_4ebc_9d6c_f46f136ee17f
is encoded by: hsa:6522
constant: false
is: SBO:0000252
type: Species
initial amount: NaN
is: F8W682
has only substance units: false
initial concentration: NaN
boundary condition: true
name: SLC4A2

http://identifiers.org/biomodels.db/MODEL1109130000#_a47ba377_5db8_4807_8717_acda3c6cbf9e
has only substance units: false
initial concentration: NaN
name: PTGES2
boundary condition: true
is: Q9H7Z7
constant: true
type: Species
initial amount: NaN
is: SBO:0000252
is encoded by: hsa:80142

metaM CE5869 e
has only substance units: false
constant: false
type: Species
name: lysyl-proline
notes: FORMULA: C11H22N3O3 CHARGE: 1 INCHI: EHMN_ABBREVIATION: CE5869
initial amount: NaN
is: SBO:0000247
initial concentration: 1.0
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3f028b3d_7213_49fa_8fe1_0c310a2c842b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ad9bd9cd_9a58_40bb_aec0_acd1770155cf
value: -1000.0
type: LocalParameter

metaR RE3144C
is described by: http://identifiers.org/pubmed/11012668
type: Reaction
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin D metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11012668 NOTES:
reactant: MODEL1109130000#
is: SBO:0000176
fast: false
name: RE3144
reversible: false

metaR EX cyan LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Hydrogen cyanide exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_67e02a46_fab2_4a5b_87de_7dc4edb10654
value: 0.0
type: LocalParameter

metaR FAOXC165C164x
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11514237
fast: false
reactant: MODEL1109130000#
reversible: false
type: Reaction
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID: 11514237 EC Number: NOTES: delta-2,4-dienoyl coA reductase reaction GENE_ASSOCIATION: 26063.1
name: fatty acid beta oxidation(C16:5-->C16:4)x
modifier: MODEL1109130000#
is: SBO:0000176

metaR S23T3g
type: Reaction
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.99.6
is: SBO:0000176
is version of: ECO:0000000
fast: false
reversible: false
product: MODEL1109130000#
name: beta-galactoside alpha-2,3-sialyltransferase (complex N-glycan)
notes: GENE_ASSOCIATION: (6487.4) or (6487.9) or (6487.11) or (6487.6) or (6487.7) or (6487.10) or (6487.5) or (6487.1) or (6487.2) or (6487.8) or (6487.3) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.99.6 Confidence Level: 4 AUTHORS: PMID:8333853 NOTES: NCD
is described by: http://identifiers.org/pubmed/8333853
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_5438eb95_4c63_4f80_a07c_06345e7a9993
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c8875743_43c6_4916_9b84_e4ce1f4b76ce
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a6d38fa4_8aa9_44a5_9671_4570babaadee
value: 1000.0
type: LocalParameter

metaR RE0512C
reversible: true
reactant: MODEL1109130000#
name: RE0512
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/7846063
is: SBO:0000176
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:7846063 NOTES:
is version of: http://identifiers.org/ec-code/1.1.1.35

http://identifiers.org/biomodels.db/MODEL1109130000#_47c32df9_7ffc_4a86_bcd6_423fb2f6e48e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8a8c61cf_873a_48f0_a252_6e3867c800a4
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c7fe114e_8b20_4642_894b_45dfa771ca4e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_08127984_4f62_482a_a7fd_80aa0938b631
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_aee58241_cdbd_4a24_b233_37344faf344d
is encoded by: hsa:314
has only substance units: false
boundary condition: true
initial amount: NaN
is: SBO:0000252
is: O75106
type: Species
initial concentration: NaN
constant: false
name: AOC2

metaR AGPex
type: Reaction
is: SBO:0000185
product: MODEL1109130000#
fast: false
name: alkyl glycerol phosphate transport
reactant: MODEL1109130000#
is version of: ECO:0000000
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 0 AUTHORS: NOTES: for alkly glycerol phosphate reductase (transmembrane rxn) - in homo sapiens glycerolipid metabolism NJ

http://identifiers.org/biomodels.db/MODEL1109130000#ae81f79d_5130_4029_a220_0aef6a23d432
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9caa8f92_e085_4879_a228_d04d9fad8a85
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e85b0f40_80dd_40ae_99e3_887c84c842ca
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_123005fe_a380_43e4_9c7d_c623c392082e
value: 0.0
type: LocalParameter

metaM CE5240 c
name: 2-hydroxyestrone-4-S-glutathione
type: Species
initial concentration: 1.0
constant: false
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5240
is: SBO:0000247
initial amount: NaN
boundary condition: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3a5f86e2_f210_4729_a43b_42e105c4b171
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2f5a29f_c7a6_4c72_81ea_3b73c373b022
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5869 c
has only substance units: false
boundary condition: false
type: Species
constant: false
initial amount: NaN
name: lysyl-proline
notes: FORMULA: C11H22N3O3 CHARGE: 1 INCHI: EHMN_ABBREVIATION: CE5869
is: SBO:0000247
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_4bd7109d_805b_42f5_bc3b_b4094c05492e
units: dimensionless
value: 0.0
type: LocalParameter

metaM orn D x
is: SBO:0000247
type: Species
name: D-ornithinium(1+)
is: HMDB03374
boundary condition: false
is: CHEBI:57668
has only substance units: false
initial concentration: 1.0
notes: FORMULA: C5H13N2O2 CHARGE: 1 INCHI: InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1/t4-/m1/s1
initial amount: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4ffd51c9_c441_4ad7_bd8f_5926c3d25a33
type: Species
initial concentration: NaN
is: SBO:0000252
constant: true
name: GPI
is encoded by: hsa:2821
boundary condition: true
initial amount: NaN
is: P06744
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_975ae354_4781_44a9_b516_b20c74ad7600
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b584c7b3_f757_4018_b21d_59d91822c5b6
name: MGAM
has only substance units: false
type: Species
initial amount: NaN
constant: true
boundary condition: true
is: SBO:0000252
is: O43451
is encoded by: hsa:8972
initial concentration: NaN

metaR EX 24nph LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: 2,4 dihydroxy nitrophenol exchange
type: Reaction

metaM ksi deg16 l
initial concentration: 1.0
initial amount: NaN
type: Species
constant: false
has only substance units: false
is: SBO:0000247
name: keratan sulfate I, degradation product 16
notes: FORMULA: C160H258N11O137S7 CHARGE: -7 INCHI:
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_32f82027_e31e_4fe8_864b_4b8650696fc0
has only substance units: false
constant: false
initial concentration: NaN
initial amount: NaN
type: Species
is: B4E097
name: GALT
is: SBO:0000252
boundary condition: true
is encoded by: hsa:2592

http://identifiers.org/biomodels.db/MODEL1109130000#_19fc634b_feec_40b3_a882_8b071366975f
value: 1000.0
type: LocalParameter

metaR LCADi D
is described by: http://identifiers.org/pubmed/15987839
is version of: http://identifiers.org/ec-code/1.2.1.21
is described by: http://identifiers.org/pubmed/6487654
is: SBO:0000176
reversible: false
is version of: ECO:0000304
name: lactaldehyde dehydrogenase
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/2296157
type: Reaction
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (218.1) or (223.1) or (8854.2) or (224.1) or (222.1) or (8854.1) or (221.1) or (216.1) or (8854.3) or (501.1) or (220.1) SUBSYSTEM: Pyruvate metabolism EC Number: 1.2.1.21 Confidence Level: 2 AUTHORS: PMID:15987839,PMID:2296157,PMID:6487654 NOTES: JLR- added irreversible form of LCAD
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_85e979a3_3e89_4cce_8b42_3dacb9e2723d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_501371bf_6aa3_49b9_8817_b1bac0907eb1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2f847a4_e40b_4c01_bc1b_cef6576c5e54
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_224b3912_182d_440b_aa6b_c18fee68eec9
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1G3:ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V1C1:ATP6V1E1:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_95c4470b_8046_4abf_90a7_1b7fd0c3e756
value: 0.0
type: LocalParameter

metaR S6TASE3ly
is described by: http://identifiers.org/pubmed/3689315
notes: GENE_ASSOCIATION: 2799.1 SUBSYSTEM: Heparan sulfate degradation EC Number: 3.1.6.14 Confidence Level: 4 AUTHORS: PMID:3196333,PMID:3689314,PMID:3689315 NOTES: NCD
reversible: true
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.1.6.14
is version of: ECO:0000000
name: N-acetylglucosamine-6-sulfatase, lysosomal
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3689314
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3196333
fast: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_207881cc_f9e2_4cff_be56_5ecd624bd94b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7c4e7184_6703_4186_9918_32e71be14d19
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b9295f12_6840_43e7_8d65_6a91c235ee3e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_71d64bc3_61f6_412d_945d_3d4c2ed5d5b2
has only substance units: false
boundary condition: true
initial amount: NaN
initial concentration: NaN
is: Q9H2F3
constant: true
type: Species
is: SBO:0000252
is encoded by: hsa:80270
name: HSD3B7

http://identifiers.org/biomodels.db/MODEL1109130000#bf079050_c06e_493c_a5f0_a986b8fed7c7
value: -1000.0
type: LocalParameter

metaR ABUTt2r
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11390972
reversible: true
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11959859
name: 4-aminobutyrate reversible transport in via proton symport
is version of: ECO:0000304
is: SBO:0000185
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 206358.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:11390972,PMID:11959859 NOTES: SAB r

metaM gly x
constant: false
is: CHEBI:15428
initial concentration: 1.0
boundary condition: false
name: glycine
initial amount: NaN
notes: FORMULA: C2H5NO2 CHARGE: 0 INCHI: InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5) HEPATONET_1.0_ABBREVIATION: HC00045 EHMN_ABBREVIATION: C00037
has only substance units: false
is: SBO:0000247
is: HMDB00123
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#ede2cb7a_1fec_40c2_bfbc_eb817c964789
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dd0d0776_f7b6_41f9_9a70_fa6b2a29e6c5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9ea82316_362a_453b_a168_e849c902b101
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_34d68cac_deb8_4cbc_8d8c_6168488dd8df
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1ed94a69_a0a6_440a_81b6_6ec316cf532c
constant: false
initial concentration: NaN
is: P22413
name: ENPP1
is: SBO:0000252
is encoded by: hsa:5167
has only substance units: false
boundary condition: true
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_8024d391_29a3_4585_9b30_6c9a47576073
value: 0.0
type: LocalParameter

metaR SEBACIDTD
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 2 AUTHORS: Glatz JFC, Luiken JJFP, Bonen A. (2010). Physiological Reviews 90: 367-417, Kamp F, Hamilton JA. (2006). Prostaglandins, Leukotrienes and Essential Fatty Acids 75: 149-59, PMCID: PMC2785172, Evtodienko VY, Bondarenko DI, Antonenko YN. (1999). Biochimica et Biophysica Acta (BBA) - Biomembranes 1420: 95-103 EC Number: NOTES: simple diffusion of fatty acids freely across membranes GENE_ASSOCIATION:
is: SBO:0000185
fast: false
reversible: true
name: transport of sebacic acid into cytosol (diffusion)
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_29080a29_a898_4463_bbe3_505c3b4a6283
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_54744d5c_b64c_4dc6_81d3_4e3583179926
units: dimensionless
value: 0.0
type: LocalParameter

metaM leuktrA4 r
is: SBO:0000247
initial amount: NaN
has only substance units: false
name: leukotriene A4(1-)
initial concentration: 1.0
is: HMDB01337
notes: FORMULA: C20H29O3 CHARGE: -1 INCHI: InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-13,15,18-19H,2-5,8,14,16-17H2,1H3,(H,21,22)/p-1/b7-6-,10-9-,12-11+,15-13+/t18-,19-/m0/s1 EHMN_ABBREVIATION: C00909
constant: false
is: CHEBI:57463
type: Species
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_795f91da_379c_4580_843b_04143b90fa60
units: dimensionless
value: 0.0
type: LocalParameter

metaR C80CPT1
modifier: MODEL1109130000#
is: SBO:0000176
reversible: true
fast: false
is described by: http://identifiers.org/pubmed/21083904
name: production of octanoylcarnitine
is described by: http://identifiers.org/pubmed/20413428
type: Reaction
reactant: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID: 21083904, PMID: 20413428 EC Number: NOTES: GENE_ASSOCIATION: (1374.1 or 1375.1 or 126129.1)
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_9a5b4df4_3a81_495e_952c_530eb14b61ec
units: dimensionless
value: 0.0
type: LocalParameter

metaR GLCtly
product: MODEL1109130000#
type: Reaction
name: glucose efflux from lysosome
reactant: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/8993166
is: SBO:0000185
fast: false
is described by: http://identifiers.org/pubmed/1751541
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, lysosomal EC Number: Confidence Level: 2 AUTHORS: PMID:1751541,PMID:8993166 NOTES: NCD
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_64661b59_ab9f_447f_af47_9fc9d5b9997e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3c629444_eab0_4fd9_9807_6850ccaf14d0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4af53f56_82c0_45e7_8adb_5e89e4934f3e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed2bdf3c_3765_4524_81d6_be238a484e9c
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B1:ATP6V1C1:ATP6V1E1:ATP6V1G2:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_2ac2ca19_889a_4185_a982_ac0670886569
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_66163ba5_a653_4844_98e4_e76fbd4c8590
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_35a85aba_bdef_4860_a95d_a38e1d6d265f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_55218826_0103_4539_91f4_b08e429b8367
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_79cba2bf_0359_4933_a741_f563cad49ccd
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaR OCT11EFATP
is described by: http://identifiers.org/pubmed/16868315
is described by: http://identifiers.org/pubmed/17495600
is: SBO:0000185
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/16357361
product: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 3 AUTHORS: PMID: 16868315, PMID: 17901542, journal of lipid research (2006) vol 47 page 665-672, 16357361, PMID: 17495600 EC Number: NOTES: fatty acid transport proteins mediate the uptake of long and very long chain fatty acids. These transport proteins are widely distributed and thought to possess fatty acid activating properties. May requires other proteins also. GENE_ASSOCIATION: (376497.1 or 11001.1 or 11000.1 or 10999.1 or 10998.1 or 28965.1)
name: uptake of vaccenic acid by cells
type: Reaction
is described by: http://identifiers.org/pubmed/17901542
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#d9d68abb_5ecc_440f_9c44_614033c05611
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_641f135f_7f28_44f4_b809_95ced496645a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bd2e5da9_d813_4bce_8747_11a4e48539e2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_380fd723_e198_448f_b202_efbfd03237ea
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a1e78436_82a6_4606_b52b_8c00928e3211
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE3144M
name: RE3144
modifier: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/11012668
is: SBO:0000176
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 1591.1 SUBSYSTEM: Vitamin D metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11012668 NOTES:
fast: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_50c44287_3f45_43a2_b862_af1150c6f952
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b452929f_41ce_490b_b5aa_17da0d840142
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3384ea8b_fdb3_43e1_84ed_b098d6de0846
value: -1000.0
type: LocalParameter

metaR NACHEXA1ly
is: SBO:0000176
reversible: false
is described by: http://identifiers.org/pubmed/12706724
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/8993162
notes: GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Chondroitin sulfate degradation EC Number: Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: Note that this reaction is specific to beta-N-acetylhexosaminidase A and cannot be catalyzed by beta-N-acetylhexosaminidase B (or presumably beta-N-acetylhexosaminidase S). This is also a lumped reaction, representing the cleavage of GalNAc4S or GalNAc6S and N-acetylgalactosamine 4-sulfatase or 6-sulfatase. NCD
is described by: http://identifiers.org/pubmed/11707436
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10336991
type: Reaction
fast: false
name: beta-N-acetylhexosaminidase A, lysosomal
product: MODEL1109130000#
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_78aedcda_307c_43f2_8546_7063e0a86f16
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2831b510_3259_4cb9_97e9_3cbe8c416664
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5de0bdc8_3b80_425e_8f56_ad22cea9a5d4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f61492af_b21d_4b41_b97c_7fae41d260a3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2cc0ed73_0354_4112_9317_ef995c9a39fe
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c6a9a863_97ec_438a_b826_55c009186228
value: 1000.0
type: LocalParameter

metaM gly l
initial amount: NaN
type: Species
constant: false
is: HMDB00123
boundary condition: false
has only substance units: false
is: CHEBI:15428
is: SBO:0000247
name: glycine
notes: FORMULA: C2H5NO2 CHARGE: 0 INCHI: InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5) HEPATONET_1.0_ABBREVIATION: HC00045 EHMN_ABBREVIATION: C00037
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_0bdda017_8912_402f_a9a7_9b4980708ffe
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24503e4f_ad0e_49b8_b29d_30678d965cf4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ef795169_89df_4fe5_86ef_69305153e5a9
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:10007
has only substance units: false
constant: true
type: Species
boundary condition: true
name: GNPDA1
is: P46926
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_3592aac8_a7d0_4045_80d2_cf60ef20fb4c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#db8a5b1c_82ae_42e4_932c_fee8218d0abf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4fff00b4_c877_4a4f_8e8f_c58197e1027e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_450c1ddc_539e_42fa_a523_2017e6491cbf
value: 0.0
type: LocalParameter

metaM leuktrA4 n
constant: false
is: SBO:0000247
type: Species
initial concentration: 1.0
has only substance units: false
boundary condition: false
is: CHEBI:57463
name: leukotriene A4(1-)
is: HMDB01337
notes: FORMULA: C20H29O3 CHARGE: -1 INCHI: InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-13,15,18-19H,2-5,8,14,16-17H2,1H3,(H,21,22)/p-1/b7-6-,10-9-,12-11+,15-13+/t18-,19-/m0/s1 EHMN_ABBREVIATION: C00909
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_7b4b4cd4_dc89_44ee_8531_99f48161e98b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2666bf48_c29f_45d0_be6b_0c7f6dbef028
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_852cf065_03a2_4104_b71e_6eb89ad4c69b
value: -1000.0
type: LocalParameter

metaM C14849 r
name: Benzo[a]pyrene-9,10-oxide
constant: false
is: C14849
initial amount: NaN
type: Species
initial concentration: 1.0
boundary condition: false
is: SBO:0000247
notes: FORMULA: C20H12O CHARGE: 0 INCHI: InChI=1/C20H12O/c1-2-11-4-5-13-10-14-7-9-16-20(21-16)19(14)15-8-6-12(3-1)17(11)18(13)15/h1-10,16,20H EHMN_ABBREVIATION: C14849
has only substance units: false

metaR EX 4abut LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: 4-Aminobutanoate exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_506a0434_d68e_4256_a887_76d5ca872925
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8f433fe2_841c_4e6a_a3e1_711c2497405e
value: 1000.0
type: LocalParameter

metaR CSPG Bt
is version of: ECO:0000000
type: Reaction
name: chondroitin sulfate B transport, golgi to extracellular
product: MODEL1109130000#
is: SBO:0000185
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES:
reactant: MODEL1109130000#
fast: false
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#ab87a500_f803_4ecd_a408_d4860945bab7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_12b31c13_a960_4a84_963f_e02ec4a8dd65
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c88b2db9_5362_4afe_a701_af5d017ecc9c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_08caa5ad_a8ac_4807_a7d5_12f48e4a03fd
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b16c79cc_7969_4bc2_b5d6_2cc40d7352e7
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_21f0326b_9f93_411d_9b90_4bbfd9c1519d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ba936c6d_7101_45bf_95df_26891b22f9d4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c44d8e09_4171_43fa_81d0_67ea70c41d81
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ae4157bf_cc70_42ef_ae65_5025d293e086
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9ae173bd_a330_49e4_ac9a_d1c5deb695ad
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bd57aabe_a8e3_4485_b894_d8eb990099af
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ef884517_0efd_4904_8701_6477aaeae0c2
is encoded by: hsa:132789
boundary condition: true
is: Q8TDQ7
initial concentration: NaN
name: GNPDA2
constant: true
has only substance units: false
is: SBO:0000252
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_49db3c28_83d0_4d3e_9171_a318d6d2ece2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_344bc4fb_b2b1_4ce0_8ceb_b625d6988771
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9d63ba7a_7034_4918_9166_a53a4ecfe70e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_898442e1_f7a0_4bc3_bd0a_6d8904ad3ae7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a3f79517_4473_42e9_9eec_2dc0e5b0da1e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d3e670a8_68f4_46f1_ab0e_81edc3ef2b7b
value: -1000.0
type: LocalParameter

metaR HSAT3ly
name: heparan-glucosaminide N-acetyltransferase, lysosomal
fast: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Heparan sulfate degradation EC Number: 2.3.1.78 Confidence Level: 4 AUTHORS: PMID:15591281,PMID:8993162 NOTES: The proton is located in the lysosome since it comes from oxidation of the NH3+ group in glucosamine. This reaction assumes that the other proton liberated from glucosamine reduces coa in the cytosol. NCD
is described by: http://identifiers.org/pubmed/8993162
type: Reaction
is: SBO:0000185
reversible: false
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/15591281
is version of: http://identifiers.org/ec-code/2.3.1.78
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#bb24a9ae_9130_40ee_9602_d5a23411c3dc
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_37ce9264_8175_4052_870b_bf819ad0f60e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_22bc761e_a48c_4f2a_8d44_10fea66f0ad3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b8d0a13_7b1a_407d_bb0b_3785cdb77b3d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c9e0bf04_679e_4b4e_a55b_f73ee660fbb0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8991fb54_b9da_474d_964f_54ac041a5767
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_35232507_321c_4b1e_9a7d_a60d6071f5cf
initial amount: NaN
initial concentration: NaN
is encoded by: hsa:768
is: SBO:0000252
has only substance units: false
boundary condition: true
is: Q16790
constant: false
name: CA9
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_639ac30f_9f08_4f27_acaf_c97e804eaffd
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8a7e6504_b97d_4876_adcd_2f3bfa65a24e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_68bae978_29b2_4c48_8fae_ca03b0e6b594
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_09f8f4ec_9648_40fa_a887_7ebdbcc9d625
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_bdcc12ec_b176_407b_9fbe_51af6115666b
type: Species
initial amount: NaN
constant: false
is: SBO:0000252
has only substance units: false
boundary condition: true
initial concentration: NaN
name: PIGN
is encoded by: hsa:23556

http://identifiers.org/biomodels.db/MODEL1109130000#_61ac85d9_a48e_4458_ae53_840dede0f5da
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf030dd3_5921_49fb_8380_0f61617d83a1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5f1612fe_4bf9_441f_8a9f_65e6dbed5f13
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_64ba8836_894f_414c_a060_038c0f1bef7b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1a0cc28a_31bb_4c24_bc68_4d513b5684e4
value: 0.0
type: LocalParameter

metaR RE1836X
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.3.1.154
fast: false
is described by: http://identifiers.org/pubmed/10706581
notes: GENE_ASSOCIATION: 6342.1 SUBSYSTEM: Bile acid synthesis EC Number: 2.3.1.154 Confidence Level: 0 AUTHORS: PMID:10706581 NOTES:
modifier: MODEL1109130000#
product: MODEL1109130000#
reversible: true
reactant: MODEL1109130000#
name: RE1836
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#f08f31ce_f6bf_4e31_99d8_5059ad34824d
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed2d4903_47b1_431a_8320_40916925fd5a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d5eceafa_758e_4334_912c_1ea349bef3bb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a4e3c267_8e96_4066_9163_8aae3b3e1ee0
boundary condition: true
is: SBO:0000252
is encoded by: hsa:54539
initial amount: NaN
constant: true
has only substance units: false
is: Q9NX14
name: NDUFB11
type: Species
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_532efdd1_3cca_432c_b00a_e7be57624407
value: 1000.0
type: LocalParameter

metaM gly m
is: C00037
is: HMDB00123
initial amount: NaN
type: Species
boundary condition: false
constant: false
notes: FORMULA: C2H5NO2 CHARGE: 0 HEPATONET_1.0_ABBREVIATION: HC00045 EHMN_ABBREVIATION: C00037 INCHI: InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
is: CHEBI:15428
is: SBO:0000247
name: Glycine
has only substance units: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_0c8ff065_28a1_4e4f_af8a_36f8fefe4602
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6ba8fb81_02d9_4580_8a12_8cca12225c3e
value: -1000.0
type: LocalParameter

metaR FAOXC165C164m
name: fatty acid beta oxidation (C16:5-->C16:4)m
is described by: http://identifiers.org/pubmed/7818482
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
reversible: false
type: Reaction
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID: 7818482 EC Number: NOTES: 2,4-dienoyl coA reductase GENE_ASSOCIATION: 1666.1
is: SBO:0000176
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#b0395db3_a2fa_4eea_a697_a22b7359c1bf
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE1539X
reactant: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11454677
is: SBO:0000176
is described by: http://identifiers.org/pubmed/9359869
notes: GENE_ASSOCIATION: 196743.1 SUBSYSTEM: Urea cycle EC Number: 1.5.3.11 Confidence Level: 0 AUTHORS: PMID:11454677,PMID:9359869 NOTES:
fast: false
product: MODEL1109130000#
name: RE1539
is version of: http://identifiers.org/ec-code/1.5.3.11
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_59caea50_7857_4cf2_baeb_c16cbcc0816d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7c3a4969_4939_424f_b7b4_af8ce1a07420
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5fe70fc2_fb13_4ea5_a941_65408f09dd67
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_197004f6_7a22_4cda_bc3a_e27fb3525e3b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_51e639a6_5127_4892_88ae_5ff67d498d96
is encoded by: hsa:3081
initial concentration: NaN
has only substance units: false
type: Species
is: SBO:0000252
boundary condition: true
is: Q93099
constant: false
initial amount: NaN
name: HGD

metaR DURIt
fast: false
is version of: ECO:0000000
type: Reaction
name: deoxyuridine transport via diffusion
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:10899995 NOTES:
is: SBO:0000185
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10899995
reversible: true
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#dc478854_4c79_45dc_bf22_6f0ca1307e35
units: dimensionless
value: 0.0
type: LocalParameter

metaM ppi c
name: Diphosphate
is: HMDB00250
has only substance units: false
initial amount: NaN
constant: false
initial concentration: 1.0
is: C00013
notes: FORMULA: HO7P2 CHARGE: -3 INCHI:
is: SBO:0000247
type: Species
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_819500b3_4f7a_477c_8479_2c855e0bcc19
value: -1000.0
type: LocalParameter

metaM dedolp L c
is: SBO:0000247
has only substance units: false
constant: false
initial amount: NaN
boundary condition: false
name: Dehydrodolichol phosphate, human liver homolog
initial concentration: 1.0
type: Species
notes: FORMULA: C1080H1738O40P10 CHARGE: -20

metaR r0728
fast: false
name: (S)-Hydroxydecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
is described by: http://identifiers.org/pubmed/8188243
is version of: http://identifiers.org/ec-code/4.2.1.17
product: MODEL1109130000#
type: Reaction
reversible: true
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8012501

metaM CE3140 c
name: 1-(1,2,3,4,5-pentahydroxypent-1-yl)-1,2,3,4-tetrahydro-beta-carboline-3-carboxylate
is: SBO:0000247
type: Species
initial concentration: 1.0
notes: FORMULA: C17H22N2O7 CHARGE: 0 INCHI: EHMN_ABBREVIATION: CE3140
boundary condition: false
initial amount: NaN
has only substance units: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#cb60a5d5_97ef_4dd6_9eb7_a386c8131900
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e4656085_2af5_4cdf_a13c_e517c5584e4c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b14e783b_25b8_4ad6_834c_1d61d8a810fe
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_20546f48_d1c6_40e8_91c6_b39d17a867ad
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d7ab0acc_d27d_428e_a920_69d1e1d65a06
value: 0.0
type: LocalParameter

metaM 1mncam e
type: Species
name: 1-methylnicotinamide
boundary condition: false
notes: FORMULA: C7H9N2O CHARGE: 1 INCHI: InChI=1S/C7H8N2O/c1-9-4-2-3-6(5-9)7(8)10/h2-5H,1H3,(H-,8,10)/p+1 EHMN_ABBREVIATION: C02918
is: HMDB00699
is: CHEBI:16797
initial amount: NaN
has only substance units: false
is: SBO:0000247
constant: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#e1281656_4469_41cb_8aa5_ca1fec1ee473
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_30c03aec_083d_4101_9424_4123652080e3
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#be6606c3_cfda_40ac_a6d2_336ddd6cd6bb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_883cbe53_9dcc_4578_b2c0_bfe2da9abac3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f228b645_dc04_4ed2_b2b7_e13649f6c5ae
value: 0.0
type: LocalParameter

metaR ADRNCPT1
is version of: ECO:0000000
notes: GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: NOTES: NJ
product: MODEL1109130000#
fast: false
reactant: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#
name: carnitine O-palmitoyltransferase
is: SBO:0000176
type: Reaction
is version of: http://identifiers.org/ec-code/2.3.1.21

metaR MM6B1bg
is described by: http://identifiers.org/pubmed/10915796
reversible: false
reactant: MODEL1109130000#
fast: false
modifier: MODEL1109130000#
is: SBO:0000176
type: Reaction
name: mannosyl-oligosaccharide 1,2-alpha-mannosidase, Golgi apparatus
is described by: http://identifiers.org/pubmed/9592125
is version of: http://identifiers.org/ec-code/3.2.1.113
is version of: ECO:0000000
notes: GENE_ASSOCIATION: (10905.1) or (57134.1) or (4121.1) SUBSYSTEM: N-glycan synthesis EC Number: 3.2.1.113 Confidence Level: 0 AUTHORS: PMID:10915796,PMID:9592125 NOTES: NCD
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_67dd1a35_d393_4d64_b175_3102bcdc9c06
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e798cd05_debf_4a52_bca9_d9b2a97ea43b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8dddbf6d_c9f9_46a7_9e35_246e4bf1f108
units: dimensionless
value: 0.0
type: LocalParameter

metaR INOSTO
fast: false
notes: GENE_ASSOCIATION: 55586.1 SUBSYSTEM: Inositol phosphate metabolism EC Number: 1.13.99.1 Confidence Level: 4 AUTHORS: PMID:15504367 NOTES: NCD
name: inositol oxygenase
reversible: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.13.99.1
modifier: MODEL1109130000#
is version of: ECO:0000269
type: Reaction
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/15504367

metaR r0727
is described by: http://identifiers.org/pubmed/7150615
is described by: http://identifiers.org/pubmed/10329704
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9553139
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.1.1.35
is described by: http://identifiers.org/pubmed/8687463
name: (S)-Hydroxydecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
reversible: false
is described by: http://identifiers.org/pubmed/1550553
is described by: http://identifiers.org/pubmed/1651711
is: SBO:0000176
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
is described by: http://identifiers.org/pubmed/10231530
is described by: http://identifiers.org/pubmed/8188243
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_428817f0_2fb9_417f_bbd3_b56f0dfaca14
value: 1000.0
type: LocalParameter

metaM ppi e
name: Diphosphate
initial amount: NaN
constant: false
has only substance units: false
initial concentration: 1.0
is: C00013
is: SBO:0000247
type: Species
notes: FORMULA: HO7P2 CHARGE: -3 HEPATONET_1.0_ABBREVIATION: HC00023 EHMN_ABBREVIATION: C00013 INCHI: InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3
is: CHEBI:33019
is: HMDB00250
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#c1eae05b_3453_4635_88fb_8586d2b1464c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_054725dc_4228_4b9d_9b3d_da0d8557642f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f841cf66_a5d2_4cf0_8491_e34752300529
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c05773cb_b553_486d_b2f6_321a552ee947
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_997baeee_d241_45ee_a3bb_70e79ceec1ab
units: dimensionless
value: 0.0
type: LocalParameter

metaM 1mncam c
notes: FORMULA: C7H9N2O CHARGE: 1 INCHI: InChI=1S/C7H8N2O/c1-9-4-2-3-6(5-9)7(8)10/h2-5H,1H3,(H-,8,10)/p+1 EHMN_ABBREVIATION: C02918
is: SBO:0000247
is: CHEBI:16797
is: HMDB00699
type: Species
constant: false
initial amount: NaN
boundary condition: false
has only substance units: false
name: 1-methylnicotinamide
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_ef160f87_12f6_4573_8637_1aba6bc89ed3
initial amount: NaN
is encoded by: hsa:54995
has only substance units: false
constant: false
type: Species
initial concentration: NaN
boundary condition: true
is: SBO:0000252
name: OXSM
is: Q9NWU1

http://identifiers.org/biomodels.db/MODEL1109130000#_7dd2b719_390b_48f0_be06_47d17f80d348
value: 1000.0
type: LocalParameter

metaM glygn4 e
notes: FORMULA: C18H31O16X CHARGE: 0 INCHI:
type: Species
boundary condition: false
initial amount: NaN
has only substance units: false
is: SBO:0000247
constant: false
name: glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#de88abee_2c2b_4050_b571_70a114fc2d11
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8db34f46_fc25_49fc_aba3_55516c8684dc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bd345d9f_dc07_4bdf_94de_8695aa86d390
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a83b915c_f7ef_4f13_be89_a37b08bbec32
value: 0.0
type: LocalParameter

metaR NACHEXA15ly
name: beta-N-acetylhexosaminidase A, lysosomal
is described by: http://identifiers.org/pubmed/12706724
is described by: http://identifiers.org/pubmed/11707436
type: Reaction
is version of: ECO:0000000
product: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/8993162
notes: GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Keratan sulfate degradation EC Number: Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: Note that this reaction is specific to beta-N-acetylhexosaminidase A and cannot be catalyzed by beta-N-acetylhexosaminidase B (or presumably beta-N-acetylhexosaminidase S). This is also a lumped reaction, representing the cleavage of GalNAc4S or GalNAc6S and N-acetylgalactosamine 4-sulfatase or 6-sulfatase. NCD
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10336991
reactant: MODEL1109130000#
fast: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_0365bd36_0b6a_4886_9962_9b8754c6c4e7
value: 1000.0
type: LocalParameter

metaM itaccoa m
boundary condition: false
initial amount: NaN
name: itaconyl-CoA(5-)
is: CHEBI:57381
type: Species
notes: FORMULA: C26H35N7O19P3S CHARGE: -5 INCHI: InChI=1S/C26H40N7O19P3S/c1-13(25(39)40)8-16(35)56-7-6-28-15(34)4-5-29-23(38)20(37)26(2,3)10-49-55(46,47)52-54(44,45)48-9-14-19(51-53(41,42)43)18(36)24(50-14)33-12-32-17-21(27)30-11-31-22(17)33/h11-12,14,18-20,24,36-37H,1,4-10H2,2-3H3,(H,28,34)(H,29,38)(H,39,40)(H,44,45)(H,46,47)(H2,27,30,31)(H2,41,42,43)/p-5/t14-,18-,19-,20+,24-/m1/s1 EHMN_ABBREVIATION: C00531
constant: false
initial concentration: 1.0
is: HMDB03377
has only substance units: false
is: SBO:0000247

metaR r0729
is described by: http://identifiers.org/pubmed/8188243
name: (S)-Hydroxydecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
is version of: http://identifiers.org/ec-code/4.2.1.17
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
product: MODEL1109130000#
fast: false
type: Reaction
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8012501

http://identifiers.org/biomodels.db/MODEL1109130000#_1ea32d0e_06c8_4a43_b885_ffd4909ba8cb
constant: false
boundary condition: true
name: _H77542_1_r
type: Species
initial concentration: NaN
is: SBO:0000252
initial amount: NaN
is encoded by: hsa:H77542
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_bd00886f_d1e3_4942_b1dd_0af0dc1ea351
constant: false
boundary condition: true
type: Species
name: CYP7B1
is: SBO:0000252
is: O75881
initial amount: NaN
initial concentration: NaN
is encoded by: hsa:9420
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_2e73e4ed_c6a1_4011_860c_3873c9feab52
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_26728574_8952_4ea8_b8e6_3d00303ef622
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6dc940aa_49e4_4ed8_b0a8_11e6777ceac8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_14cd472a_88b0_483a_a919_a7c4dd37c85c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5daf2557_c7ea_49c9_9b28_8a982f406ada
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9599b64e_2e7b_4212_9f02_224688356a55
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_247629b3_42b0_4039_8db0_e9e831e25dfc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1140f432_91a9_4d31_b529_981614a45cd7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7f749d84_49d7_49e8_8a90_a4347bcf1611
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_49717918_1f80_4b1c_9532_c84a223a986b
initial amount: NaN
name: DNMT1
constant: true
initial concentration: NaN
is: SBO:0000252
is: I6L9H2
has only substance units: false
type: Species
is encoded by: hsa:1786
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_23471fde_b418_491d_b5c2_5fbd265a8acf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8cec67c2_62b0_4655_acd6_283d83cc4f3a
is: SBO:0000252
initial concentration: NaN
name: PDE5A
constant: true
initial amount: NaN
boundary condition: true
is encoded by: hsa:8654
has only substance units: false
type: Species

metaR RE1537X
reactant: MODEL1109130000#
is: SBO:0000176
name: RE1537
reversible: false
is version of: http://identifiers.org/ec-code/1.5.3.11
is described by: http://identifiers.org/pubmed/11454677
type: Reaction
notes: GENE_ASSOCIATION: 196743.1 SUBSYSTEM: Urea cycle EC Number: 1.5.3.11 Confidence Level: 0 AUTHORS: PMID:11454677,PMID:9359869 NOTES:
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9359869
fast: false
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_49feaeab_4378_4b93_b63f_83afbd1b4588
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cdb4f971_d109_45bc_a7c5_e4707bbf28f9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9ff46e6b_76d1_4260_bdaa_a74b3513f523
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_194215dd_a864_4a7c_a598_7d994aa132e9
value: 0.0
type: LocalParameter

metaR r0724
is: SBO:0000176
type: Reaction
name: Decanoyl-CoA:acetyl-CoA C-acyltransferase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:2.3.1.16
reversible: true
notes: GENE_ASSOCIATION: (AI924226.1) or (53354.1) or (80025.1) or (79646.1) or (55229.1) or (100128062.1) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.16 Confidence Level: 0 AUTHORS: PMID:1121274,PMID:1679347,PMID:3194209,PMID:6378901,PMID:8241273 NOTES:
is described by: http://identifiers.org/pubmed/1679347
is described by: http://identifiers.org/pubmed/1121274
fast: false
is described by: http://identifiers.org/pubmed/3194209
reactant: MODEL1109130000#
product: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8241273
is version of: http://identifiers.org/ec-code/2.3.1.16
is described by: http://identifiers.org/pubmed/6378901

metaM CE6464 c
boundary condition: false
constant: false
name: 17-hydroxy-E4-neuroprostane
initial concentration: 1.0
has only substance units: false
initial amount: NaN
type: Species
is: SBO:0000247
notes: FORMULA: C22H31O5 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE6464

http://identifiers.org/biomodels.db/MODEL1109130000#_891fefcf_ff23_4644_b858_57846ba4c304
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e0f4d463_c89f_4eda_b229_25597ae98f35
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4263d281_dcbb_4f7b_ac42_c3d52eff6eaf
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_01637fdd_055b_4402_8ea8_7e60d80c1854
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f7e8a67_404d_4ab5_901e_32ff975b8dd4
value: 0.0
type: LocalParameter

metaR r0723
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7150615
is version of: http://identifiers.org/ec-code/1.1.1.35
is described by: http://identifiers.org/pubmed/10231530
is described by: http://identifiers.org/pubmed/1550553
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1651711
is described by: http://identifiers.org/pubmed/8687463
is described by: http://identifiers.org/pubmed/9553139
name: (S)-3-Hydroxydodecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
fast: false
notes: GENE_ASSOCIATION: (AA177072.1) or (2194.1) or (54995.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
is described by: http://identifiers.org/pubmed/8188243
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10329704
is: SBO:0000176
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#d7c8369c_4ba4_44f5_bf76_74bf47b60796
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f42a1fbe_1768_4fb7_b157_ce2e4dd8efb1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_35d3caa4_481f_4422_9617_8b15ff39fe98
boundary condition: true
is: P43251
is encoded by: hsa:686
initial amount: NaN
constant: false
type: Species
has only substance units: false
initial concentration: NaN
name: BTD
is: SBO:0000252

metaM leuktrA4 e
initial amount: NaN
initial concentration: 1.0
is: CHEBI:57463
is: SBO:0000247
name: leukotriene A4(1-)
has only substance units: false
boundary condition: false
constant: false
is: HMDB01337
notes: FORMULA: C20H29O3 CHARGE: -1 INCHI: InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-13,15,18-19H,2-5,8,14,16-17H2,1H3,(H,21,22)/p-1/b7-6-,10-9-,12-11+,15-13+/t18-,19-/m0/s1 EHMN_ABBREVIATION: C00909
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#bdefcf45_efbc_4412_a117_f122cb6902e4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8f31033a_3f4e_4b66_934a_b982c20cfd81
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#af224650_e1a4_48d7_9c91_f32d1317f5c2
value: 0.0
type: LocalParameter

metaR r2100
fast: false
modifier: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is: SBO:0000185
reversible: true
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_81f13d2d_95d6_44db_bb8a_3b6c91a6dc79
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aa2ccada_4789_4cbc_9fdc_812e5c171bdb
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0bef429a_3a8b_4424_b716_07607dbf2183
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1G3:ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B1:ATP6V1C1:ATP6V1E2:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_4d8d29e0_9890_4d68_8ca2_3c814d882972
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b3d0dabc_5b2b_4165_9878_e95fe0d7773b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c8d16d13_6d79_4e41_be4b_2f4add8ee496
value: 0.0
type: LocalParameter

metaR r0726
type: Reaction
name: (S)-Hydroxydecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
is described by: http://identifiers.org/pubmed/10231530
is described by: http://identifiers.org/pubmed/8188243
is described by: http://identifiers.org/pubmed/1550553
is described by: http://identifiers.org/pubmed/10329704
is described by: http://identifiers.org/pubmed/1651711
is described by: http://identifiers.org/pubmed/8687463
is described by: http://identifiers.org/pubmed/9553139
notes: GENE_ASSOCIATION: (AI924226.1) or (53354.1) or (80025.1) or (79646.1) or (55229.1) or (100128062.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
reactant: MODEL1109130000#
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/1.1.1.35
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7150615
is: SBO:0000176
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#d72ef688_f9a7_4a38_a0b3_c75ee5a675cd
value: 0.0
type: LocalParameter

metaR EX nadp LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Nicotinamide adenine dinucleotide phosphate exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_599b12da_121d_48f4_ae2a_d38dc2118059
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_71fe0683_a04f_46ae_9286_f71af65da4fa
is encoded by: hsa:3906
type: Species
has only substance units: false
is encoded by: hsa:2683
has part: P00709
has part: P15291
boundary condition: true
initial amount: NaN
name: B4GALT1:LALBA
initial concentration: NaN
constant: true
is: SBO:0000297

http://identifiers.org/biomodels.db/MODEL1109130000#fee64ea0_a9e4_44ab_bd1e_e2f39f4a31a0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ae7e9cff_eb86_480a_96d8_4e18dd0454fe
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed8a162e_04a6_4ac3_9289_d2d4a8edc2b0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b96230a4_aa74_49a3_b189_f59d17103e0e
value: 1000.0
type: LocalParameter

metaM dhlpro m
notes: FORMULA: H2S2X CHARGE: 0 EHMN_ABBREVIATION: C02972 INCHI:
is: CHEBI:16194
type: Species
initial concentration: 1.0
name: Dihydrolipolprotein
constant: false
initial amount: NaN
boundary condition: false
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#f912aa08_03b9_4e52_9ed3_86b9e6ef77d6
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69d21bcd_5850_4e14_8ae7_fc3856bee677
value: 1000.0
type: LocalParameter

metaM leuktrA4 c
initial concentration: 1.0
is: SBO:0000247
constant: false
name: leukotriene A4(1-)
notes: FORMULA: C20H29O3 CHARGE: -1 INCHI: InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-13,15,18-19H,2-5,8,14,16-17H2,1H3,(H,21,22)/p-1/b7-6-,10-9-,12-11+,15-13+/t18-,19-/m0/s1 EHMN_ABBREVIATION: C00909
initial amount: NaN
type: Species
is: CHEBI:57463
has only substance units: false
boundary condition: false
is: HMDB01337

metaR DTDPtn
fast: false
is version of: ECO:0000000
is: SBO:0000185
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, nuclear EC Number: Confidence Level: 2 AUTHORS: NOTES: NCD
name: dTDP nuclear transport
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: true

metaR EX estradiolglc LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: estradiol glucuronide exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_18b326a2_6337_4f0f_8072_310d38a920fa
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6c31b15d_1c01_4b8a_99e2_db1718a58038
units: dimensionless
value: 0.0
type: LocalParameter

metaR r0720
is version of: http://identifiers.org/ec-code/4.2.1.17
name: (S)-3-Hydroxytetradecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8012501
is described by: http://identifiers.org/pubmed/8188243
reversible: false
type: Reaction
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_05da2b5a_2aac_4d99_b88d_978d4c4c85cf
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_70a2ecd2_509e_4ba3_ab06_5d7fc15f1c86
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3a8e9fd6_3db1_46a8_9db6_16cc533a64f3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9a7b7404_b461_4190_882f_e1c27db691a2
value: 0.0
type: LocalParameter

metaR MM7Cag
product: MODEL1109130000#
type: Reaction
is: SBO:0000176
is version of: http://identifiers.org/ec-code/3.2.1.113
is described by: http://identifiers.org/pubmed/10915796
reversible: false
is described by: http://identifiers.org/pubmed/9592125
fast: false
is version of: ECO:0000000
reactant: MODEL1109130000#
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (4121.1) or (57134.1) or (10905.1) SUBSYSTEM: N-glycan synthesis EC Number: 3.2.1.113 Confidence Level: 0 AUTHORS: PMID:10915796,PMID:9592125 NOTES: NCD
name: mannosyl-oligosaccharide 1,2-alpha-mannosidase, Golgi apparatus

http://identifiers.org/biomodels.db/MODEL1109130000#ebefef2e_3226_48fa_b57b_cb4a48bc0803
value: -1000.0
type: LocalParameter

metaR 5HTRPDOX
name: 5-Hydroxy-L-tryptophan:oxygen 2,3-dioxygenase (indole-decyclizing)
is: SBO:0000176
type: Reaction
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10564724
fast: false
notes: GENE_ASSOCIATION: 3620.1 SUBSYSTEM: Tryptophan metabolism EC Number: 1.13.11.52 Confidence Level: 1 AUTHORS: PMID:10564724 NOTES: SAB. The E.C. number 1.13.11.42 has been deleted in 2006. Instead, replaced with E.C. 1.13.11.11 - tryptophan 2,3-dioxygenase. However, E.C. 1.13.11.11 is for the reaction L-tryptophan + O2 = N-formyl-L-kynurenine. For the reaction 5-Hydroxy-L-tryptophan (Cytosol) + O2 (Cytosol) <=> 5-Hydroxy-N-formylkynurenine, E.C. should be 1.13.11.52. Conclusion: Change E.C. to 1.13.11.52 (source: KEGG).
is version of: http://identifiers.org/ec-code/1.13.11.52
is version of: ECO:0000134
product: MODEL1109130000#
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#b26074f9_5c7d_4427_bc0f_fd6bb010d1e3
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1399
is described by: http://identifiers.org/pubmed/5810070
is described by: http://identifiers.org/pubmed/4475632
type: Reaction
reactant: MODEL1109130000#
fast: false
is version of: http://identifiers.org/ec-code/2.3.1.7
name: carnitine acetyltransferase EC:2.3.1.7
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.7 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:
reversible: false
is described by: http://identifiers.org/pubmed/12133002
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#c1a788bd_5dd9_4e29_98c9_89a9295e6f01
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d5ddd565_fc62_4d96_af62_eca96783ad53
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f08cfbb2_501a_417a_b102_c323ac1b4e5b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f07a5b10_776f_43c1_aad3_762b7298df94
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_900eb8bb_da4b_4044_ad71_083ad2218b14
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a5de59a7_17fa_4a1c_9731_e8dbd1b1daa2
initial concentration: NaN
is: P20813
notes: DRUGBANK_INDUCER: DB00197, DB00238, DB00252, DB00257, DB00439, DB00503, DB00531, DB00564, DB00622, DB00624, DB00625, DB00636, DB00641, DB00661, DB00745, DB00753, DB00794, DB01045, DB01076, DB01095, DB01115, DB01138, DB01173, DB01174, DB01234, DB01320, DB04817, DB04868, DB04930, DB06697 DRUGBANK_SUBSTRATE: DB00184, DB00193, DB00231, DB00238, DB00281, DB00296, DB00313, DB00321, DB00333, DB00349, DB00379, DB00398, DB00454, DB00458, DB00472, DB00503, DB00514, DB00531, DB00532, DB00568, DB00586, DB00604, DB00624, DB00625, DB00655, DB00661, DB00675, DB00683, DB00748, DB00751, DB00753, DB00755, DB00758, DB00762, DB00772, DB00818, DB00829, DB00835, DB00836, DB00849, DB00850, DB00865, DB01028, DB01037, DB01069, DB01074, DB01075, DB01104, DB01156, DB01159, DB01181, DB01184, DB01221, DB01236, DB01435, DB01466, DB01544, DB01559, DB04841, DB04871, DB04930, DB04938, DB06148, DB06209, DB06697, DB06710, DB06770 DRUGBANK_UNKNOWN: DB02974, DB03014, DB04664, DB04794, DB08369 DRUGBANK_INHIBITOR: DB00169, DB00176, DB00208, DB00215, DB00220, DB00257, DB00285, DB00381, DB00398, DB00435, DB00481, DB00503, DB00515, DB00625, DB00675, DB00701, DB00715, DB00745, DB00753, DB00758, DB00763, DB00778, DB00898, DB00908, DB00972, DB00997, DB01026, DB01043, DB01104, DB01110, DB01151, DB01156, DB01167, DB01173, DB01394, DB01435, DB01601, DB03575, DB04572, DB06729, DB08864, DB08896, DB08899
initial amount: NaN
is: SBO:0000252
is encoded by: hsa:1555
name: CYP2B6
type: Species
boundary condition: true
constant: false
has only substance units: false

metaR RE1538C
reversible: false
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Urea cycle EC Number: 1.5.3.11 Confidence Level: 0 AUTHORS: PMID:11454677,PMID:9359869 NOTES:
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11454677
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.5.3.11
type: Reaction
name: RE1538
is: SBO:0000176
is described by: http://identifiers.org/pubmed/9359869

metaR r0722
name: (S)-3-Hydroxydodecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
is described by: http://identifiers.org/pubmed/8188243
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/8687463
is described by: http://identifiers.org/pubmed/7150615
is described by: http://identifiers.org/pubmed/10329704
is described by: http://identifiers.org/pubmed/1651711
is described by: http://identifiers.org/pubmed/10231530
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 5805.1 SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.1.1.35
reversible: true
is described by: http://identifiers.org/pubmed/1550553
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9553139
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_0a3d554d_ccc4_4a28_8cb4_458f79487597
value: 1000.0
type: LocalParameter

metaR RE3140X
name: RE3140
is version of: http://identifiers.org/ec-code/4.2.1.17
is described by: http://identifiers.org/pubmed/11734209
reversible: true
fast: false
product: MODEL1109130000#
is: SBO:0000176
type: Reaction
modifier: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 1962.1 SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:11734209 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#ca1144af_a848_450c_878c_c73efd9d233b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ed06fcae_e1ce_4dfc_a1b8_d6cee94443af
initial amount: NaN
boundary condition: true
initial concentration: NaN
is encoded by: hsa:124583
name: CANT1
has only substance units: false
constant: true
is: SBO:0000252
type: Species
is: Q8WVQ1

http://identifiers.org/biomodels.db/MODEL1109130000#_37d874a4_a0ad_447d_be34_4a4a81b97517
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_cab1cc80_9392_44e7_8b43_2c444c8e1e91
initial amount: NaN
constant: false
has only substance units: false
is encoded by: hsa:56474
is: Q9NRF8
name: CTPS2
type: Species
is: SBO:0000252
boundary condition: true
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_3996271c_39d7_4677_bd9a_928b7e58e0a9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f8dd35d1_2507_40f6_ad43_297fa80d83d8
value: 0.0
type: LocalParameter

metaR r0721
type: Reaction
product: MODEL1109130000#
name: (S)-3-Hydroxytetradecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
reversible: false
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
is version of: http://identifiers.org/ec-code/4.2.1.17
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8012501
is described by: http://identifiers.org/pubmed/8188243

metaR RE1096M
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 1586.1 SUBSYSTEM: Steroid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:10049998,PMID:7578007 NOTES:
is described by: http://identifiers.org/pubmed/10049998
modifier: MODEL1109130000#
name: RE1096
type: Reaction
product: MODEL1109130000#
is: SBO:0000176
reversible: false
is described by: http://identifiers.org/pubmed/7578007
fast: false

metaM hexccoa x
boundary condition: false
type: Species
is: SBO:0000247
constant: false
initial concentration: 1.0
initial amount: NaN
is: HMDB06459
has only substance units: false
name: Hexacosanoyl-CoA (n-C26:0CoA)
notes: FORMULA: C47H82N7O17P3S CHARGE: -4 INCHI: InChI=1/C47H86N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-38(56)75-31-30-49-37(55)28-29-50-45(59)42(58)47(2,3)33-68-74(65,66)71-73(63,64)67-32-36-41(70-72(60,61)62)40(57)46(69-36)54-35-53-39-43(48)51-34-52-44(39)54/h34-36,40-42,46,57-58H,4-33H2,1-3H3,(H,49,55)(H,50,59)(H,63,64)(H,65,66)(H2,48,51,52)(H2,60,61,62)/p-4/t36-,40-,41-,42+,46-/m1/s1

http://identifiers.org/biomodels.db/MODEL1109130000#a6b47fcf_68cc_4621_9329_063297e037e3
value: 0.0
type: LocalParameter

metaM C04853 m
initial amount: NaN
constant: false
has only substance units: false
is: HMDB01509
boundary condition: false
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C20H31O5 CHARGE: -1 INCHI: InChI=1S/C20H32O5/c21-17-10-6-2-1-3-7-12-18(22)13-8-4-5-9-14-19(23)15-11-16-20(24)25/h3-5,7-9,13-14,18-19,21-23H,1-2,6,10-12,15-17H2,(H,24,25)/p-1/b5-4+,7-3-,13-8+,14-9-/t18-,19-/m1/s1 EHMN_ABBREVIATION: C04853
name: 20-hydroxy-leukotriene B4(1-)
is: CHEBI:57460
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_306e4572_75e4_4d9e_a92f_69bfa0902bea
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c046ec33_af3d_4d51_9caa_3ff868f4217a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7de71bc5_71a1_4c2e_94ab_653868ec5be4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#caed6226_f8a6_432b_9486_ad07cd4b8532
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_43c3db9b_1433_4de9_8ef5_a9297bb5a229
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31b58b47_5dec_47c5_92b6_867acbc11a7a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_945d91f0_791f_46b5_b6e8_092bad8a4c3f
units: dimensionless
value: 0.0
type: LocalParameter

metaR FUCASE2ly
is described by: http://identifiers.org/pubmed/1769200
is described by: http://identifiers.org/pubmed/2803312
is described by: http://identifiers.org/pubmed/11870229
is version of: http://identifiers.org/ec-code/3.2.1.51
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/2983333
modifier: MODEL1109130000#
reactant: MODEL1109130000#
name: alpha-fucosidase, lysosomal
product: MODEL1109130000#
type: Reaction
is: SBO:0000176
fast: false
notes: GENE_ASSOCIATION: 2517.1 SUBSYSTEM: Keratan sulfate degradation EC Number: 3.2.1.51 Confidence Level: 4 AUTHORS: PMID:11870229,PMID:1769200,PMID:2803312,PMID:2983333 NOTES: NCD
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_067fcfdc_6b9d_4b4f_bcfe_99809208d245
units: dimensionless
value: 0.0
type: LocalParameter

metaM C04853 r
initial concentration: 1.0
has only substance units: false
name: 20-hydroxy-leukotriene B4(1-)
initial amount: NaN
is: HMDB01509
boundary condition: false
notes: FORMULA: C20H31O5 CHARGE: -1 INCHI: InChI=1S/C20H32O5/c21-17-10-6-2-1-3-7-12-18(22)13-8-4-5-9-14-19(23)15-11-16-20(24)25/h3-5,7-9,13-14,18-19,21-23H,1-2,6,10-12,15-17H2,(H,24,25)/p-1/b5-4+,7-3-,13-8+,14-9-/t18-,19-/m1/s1 EHMN_ABBREVIATION: C04853
is: SBO:0000247
type: Species
is: CHEBI:57460
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#cf75d8bb_cc50_497c_ad0b_7e547277d468
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_42e166c5_278d_4829_9487_0dec143cfaa4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bea62176_cd0e_4b35_b15d_65a503375b5f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aff508cf_bc01_4268_a34d_1a77f82c1052
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fcac1309_d009_43ce_885d_ba0927c99258
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1cfe72dc_6eab_4e79_8f32_e12aaa64786b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a48b0cd_e7d9_44c7_8513_682d1207cedd
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33f8a98a_d47c_42bd_a615_d9ce6be2ca48
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8dc66258_6323_4564_8d32_ecd136cf5093
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4b73115d_4976_4117_bbfd_358ad242397d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bea364fb_bf10_4e60_9959_66f6da88f704
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_29f0d46e_ec36_47ca_ab34_ec53792720d1
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9320ad43_72d1_45c5_b5bf_835f37c317fd
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d618b220_7e43_4f00_9f10_4550adb427f8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d4ae7acd_0d57_45fa_a305_e47f26d00ca2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_63bacc93_b70c_443c_9fe2_d1fc3c46a92f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f7d0d9c1_233d_4c55_978e_e034457e5c9c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e2650533_8858_41e2_ba23_8a60bab83768
value: 1000.0
type: LocalParameter

metaR BHMT
type: Reaction
fast: false
reversible: false
is: SBO:0000176
is version of: ECO:0000269
product: MODEL1109130000#
name: betaine-homocysteine S-methyltransferase
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9281325
notes: GENE_ASSOCIATION: (23743.1) or (635.1) SUBSYSTEM: Glycine, serine, alanine and threonine metabolism EC Number: 2.1.1.5 Confidence Level: 4 AUTHORS: PMID:9281325 NOTES:
is version of: http://identifiers.org/ec-code/2.1.1.5
modifier: MODEL1109130000#

metaM CE5591 c
name: 4-OH-13-cis-retinal
has only substance units: false
notes: FORMULA: C20H28O2 CHARGE: 0 INCHI: EHMN_ABBREVIATION: CE5591
is: SBO:0000247
initial concentration: 1.0
type: Species
initial amount: NaN
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6e1ed5f8_15c7_4f1f_b155_10ee3263ceaf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8b2a5103_f2f8_4471_8163_7ea0f63c3623
value: -1000.0
type: LocalParameter

metaR TETPENT3CPT2
name: carnitine transferase
reversible: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: NOTES: NJ
type: Reaction
is version of: ECO:0000000
fast: false
reactant: MODEL1109130000#
is: SBO:0000176
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#ab5877fe_86a3_4951_a8db_84ecd11d31b1
value: 0.0
type: LocalParameter

metaR EX 7thf LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: heptaglutamyl folate (THF) exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_9a6462b0_9742_4f6a_81bc_346e9ea78c0d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aeae6d7b_1dfa_4c3b_90ac_dd6e06c7cb80
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3c5c966b_03d7_4fcd_b9e8_1117384a0378
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_dfa1e3c0_d53e_4548_ae71_fb99bca8b248
is: P08236
has only substance units: false
is: SBO:0000252
type: Species
name: GUSB
boundary condition: true
constant: true
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:2990

http://identifiers.org/biomodels.db/MODEL1109130000#_28ecf9c9_a951_4ccc_a7a1_f3d2163b8f99
name: CYP4X1
is: Q8N118
has only substance units: false
is encoded by: hsa:260293
boundary condition: true
is: SBO:0000252
initial concentration: NaN
initial amount: NaN
type: Species
constant: true

metaR GPAM hs
reactant: MODEL1109130000#
is version of: ECO:0000000
reversible: false
type: Reaction
notes: GENE_ASSOCIATION: 57678.1 SUBSYSTEM: Triacylglycerol synthesis EC Number: 2.3.1.15 Confidence Level: 4 AUTHORS: NOTES: NJ
modifier: MODEL1109130000#
name: glycerol-3-phosphate acyltransferase
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.15
fast: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_7f66edcf_d7dd_45a7_97d5_29f9f3f2d7ad
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_373c3a81_81d5_46d9_b66a_6365298d3c63
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f40e2194_7b25_4a72_9141_4309fd3d8305
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e67e9eea_5ebb_476d_9a22_bbfd37831c02
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE1096R
type: Reaction
is described by: http://identifiers.org/pubmed/10049998
is described by: http://identifiers.org/pubmed/7578007
fast: false
notes: GENE_ASSOCIATION: 1586.1 SUBSYSTEM: Steroid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:10049998,PMID:7578007 NOTES:
modifier: MODEL1109130000#
is: SBO:0000176
reversible: false
name: RE1096
product: MODEL1109130000#
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_928eadc4_e5d0_4802_9ac1_c4dfb930ca20
units: dimensionless
value: 0.0
type: LocalParameter

metaR ADRNCPT2
is version of: ECO:0000000
reactant: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: NOTES: NJ
is: SBO:0000176
name: carnitine transferase
type: Reaction
product: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#

metaR 34DHPHAMT
product: MODEL1109130000#
reversible: false
is: SBO:0000176
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1847521
is version of: http://identifiers.org/ec-code/2.1.1.6
type: Reaction
notes: GENE_ASSOCIATION: (1312.1) or (1312.2) SUBSYSTEM: Tyrosine metabolism EC Number: 2.1.1.6 Confidence Level: 1 AUTHORS: PMID:1847521 NOTES: SAB
reactant: MODEL1109130000#
name: 3,4-Dihydroxyphenylacetate:amet O-methyltransferase
fast: false
is version of: ECO:0000212

metaR CH25H
is version of: ECO:0000269
is: SBO:0000176
type: Reaction
reversible: false
name: cholesterol 25-hydroxylase
notes: GENE_ASSOCIATION: 9023.1 SUBSYSTEM: Bile acid synthesis EC Number: Confidence Level: 4 AUTHORS: NOTES: NJ
fast: false
modifier: MODEL1109130000#
product: MODEL1109130000#
reactant: MODEL1109130000#

metaR H6 ET2er
product: MODEL1109130000#
name: H6 phosphoethanolaminyl transferase, endoplasmic reticulum
is described by: http://identifiers.org/pubmed/15632136
is version of: ECO:0000000
reversible: false
is: SBO:0000176
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:15632136 NOTES: NCD
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_5deb771a_7224_4162_a459_fcad952450a3
units: dimensionless
value: 0.0
type: LocalParameter

metaR TETPENT3CPT1
reactant: MODEL1109130000#
is: SBO:0000176
name: carnitine O-palmitoyltransferase
product: MODEL1109130000#
fast: false
is version of: ECO:0000269
type: Reaction
reversible: false
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.21
notes: GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: NOTES: NJ

http://identifiers.org/biomodels.db/MODEL1109130000#_634dea52_c585_4146_99c5_c7862bc8b675
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_169ce286_4b01_4ea1_9ab2_3056161bddca
value: 1000.0
type: LocalParameter

metaR PI45PLCn
is described by: http://identifiers.org/pubmed/11118617
name: phosphatidylinositol 4,5-bisphosphate phospholipase C, nucleus
reversible: false
type: Reaction
modifier: MODEL1109130000#
is: SBO:0000176
fast: false
is described by: http://identifiers.org/pubmed/12213492
is version of: ECO:0000000
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10760467
is described by: http://identifiers.org/pubmed/12728269
notes: GENE_ASSOCIATION: (23236.1) or (23236.2) SUBSYSTEM: Inositol phosphate metabolism EC Number: 3.1.4.11 Confidence Level: 4 AUTHORS: PMID:10760467,PMID:11118617,PMID:12213492,PMID:12728269 NOTES: NCD
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.1.4.11

http://identifiers.org/biomodels.db/MODEL1109130000#_142bb64a_3c23_478b_909a_a620faf2f6b5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_130078d7_fbb2_424d_916b_c58d340cd5fd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b84a09c7_71fd_4fe5_b0a4_2a20e6e19fa4
initial amount: NaN
has only substance units: false
boundary condition: true
constant: false
type: Species
is encoded by: hsa:AGPAT7
name: _AGPAT7_1_c
is: SBO:0000252
initial concentration: NaN

metaR RE3185M
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9469587
is version of: http://identifiers.org/ec-code/1.3.99.3
is described by: http://identifiers.org/pubmed/10407780
is described by: http://identifiers.org/pubmed/9819701
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (34.1) or (33.1) or (36.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.3.99.3 Confidence Level: 0 AUTHORS: PMID:10407780,PMID:9469587,PMID:9819701 NOTES:
modifier: MODEL1109130000#
name: RE3185
reversible: true
is: SBO:0000176
type: Reaction
fast: false

metaR RE2407C
notes: GENE_ASSOCIATION: SUBSYSTEM: Cholesterol metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:0 NOTES:
is: SBO:0000176
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/0
reversible: true
fast: false
type: Reaction
product: MODEL1109130000#
name: RE2407

metaR CO2tp
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 1 AUTHORS: NOTES: NCD
reversible: true
name: CO2 peroxisomal transport
is version of: ECO:0000000
product: MODEL1109130000#
fast: false
is: SBO:0000185

metaR UGLCNACtg
is version of: ECO:0000269
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15082721
reversible: true
modifier: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 11046.1 SUBSYSTEM: Transport, golgi apparatus EC Number: Confidence Level: 4 AUTHORS: PMID:15082721,PMID:15607426 NOTES: NCD
is described by: http://identifiers.org/pubmed/15607426
name: UDP-GlcNAc Golgi transport via CMP antiport
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_2f86918f_c5fc_47c8_94e3_b8fec7cf1138
value: 0.0
type: LocalParameter

metaR PE HStg
reversible: true
type: Reaction
is described by: http://identifiers.org/pubmed/10856717
is version of: ECO:0000000
name: phosphatidylethanolamine scramblase
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, golgi apparatus EC Number: Confidence Level: 2 AUTHORS: PMID:10856717 NOTES:
is: SBO:0000185
product: MODEL1109130000#
fast: false
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_9a257256_8599_49f1_a207_2e9a05bb0448
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d96dec5b_060c_42eb_b52b_e81f42183164
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2bde3427_1943_4ee0_9659_fab9493ad7af
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0c57cd56_3526_4f4b_b4b0_0f51334097a7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f847f4dc_2ca8_4082_b52c_17cd285ed1ba
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_08b23d67_7fce_4f69_8eab_1235ba0a0277
value: 0.0
type: LocalParameter

metaR r1391
type: Reaction
fast: false
reversible: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Unassigned EC Number: 2.4.1.25 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:
product: MODEL1109130000#
name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase EC:2.4.1.25
is version of: http://identifiers.org/ec-code/2.4.1.25
is: SBO:0000176
is described by: http://identifiers.org/pubmed/5810070
is described by: http://identifiers.org/pubmed/4475632
is described by: http://identifiers.org/pubmed/12133002

metaR TYRDOPO3
name: Tyrosine:dopa oxidase (dopaquinone producing 2)
fast: false
is version of: http://identifiers.org/ec-code/1.14.18.1
is: SBO:0000176
product: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: 7299.1 SUBSYSTEM: Tyrosine metabolism EC Number: 1.14.18.1 Confidence Level: 4 AUTHORS: PMID:5294951 NOTES: SAB
modifier: MODEL1109130000#
is version of: ECO:0000269
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/5294951
reversible: false

metaM C06199 g
name: Hordenine
initial amount: NaN
is: HMDB04366
has only substance units: false
is: SBO:0000247
is: CHEBI:5764
initial concentration: 1.0
boundary condition: false
type: Species
constant: false
notes: FORMULA: C10H16NO CHARGE: 1 INCHI: InChI=1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3 EHMN_ABBREVIATION: C06199

http://identifiers.org/biomodels.db/MODEL1109130000#_329d9551_a171_4df7_8a4e_48aa2f91de28
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b28b6918_99a6_4f7e_95b6_993be09a850d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_049c08eb_e139_4504_a1a7_b34054b6dc57
value: 0.0
type: LocalParameter

metaR r1392
name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase EC:3.2.1.33
reversible: false
type: Reaction
is described by: http://identifiers.org/pubmed/4475632
is described by: http://identifiers.org/pubmed/5810070
is described by: http://identifiers.org/pubmed/12133002
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.2.1.33
is: SBO:0000176
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Unassigned EC Number: 3.2.1.33 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_09367273_5c81_422f_a762_5dda4a2add45
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_cd8b3d71_a8c2_4cbd_a96e_7ff166220bcc
is: SBO:0000252
initial concentration: NaN
is: P19404
initial amount: NaN
has only substance units: false
name: NDUFV2
constant: true
type: Species
is encoded by: hsa:4729
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#a3f551c9_740b_4733_a2fa_de3b756d5632
value: 0.0
type: LocalParameter

metaR CO2tn
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, nuclear EC Number: Confidence Level: 1 AUTHORS: NOTES: NCD
reversible: true
is version of: ECO:0000000
name: CO2 nuclear transport via diffusion
reactant: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
fast: false
is: SBO:0000185

metaM CE2303 c
name: 9-hydroxy-10-O-D-glucuronoside-12Z-octadecenoate
initial concentration: 1.0
constant: false
initial amount: NaN
type: Species
is: SBO:0000247
notes: FORMULA: C24H40O10 CHARGE: -2 INCHI: InChI=1/C24H42O10/c1-2-3-4-5-8-11-14-17(16(25)13-10-7-6-9-12-15-18(26)27)33-24-21(30)19(28)20(29)22(34-24)23(31)32/h8,11,16-17,19-22,24-25,28-30H,2-7,9-10,12-15H2,1H3,(H,26,27)(H,31,32)/p-2/b11-8-/t16u,17u,19-,20+,21-,22-,24?/m0/s1 EHMN_ABBREVIATION: CE2303
boundary condition: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4c4a7df3_df0c_49c3_bc37_9a1c24264ef8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2b828ec8_02a4_4fe7_a0d4_f586e558599b
value: 0.0
type: LocalParameter

metaR r1393
fast: false
reactant: MODEL1109130000#
reversible: false
is: SBO:0000176
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/4475632
is described by: http://identifiers.org/pubmed/5810070
notes: GENE_ASSOCIATION: SUBSYSTEM: Starch and sucrose metabolism EC Number: 2.4.1.1 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:
is described by: http://identifiers.org/pubmed/12133002
is version of: http://identifiers.org/ec-code/2.4.1.1
type: Reaction
name: EC:2.4.1.1

http://identifiers.org/biomodels.db/MODEL1109130000#_0a55c2b8_4d9d_4564_abcc_7a29e5fef59b
has only substance units: false
constant: false
initial amount: NaN
is: Q8TDX5
boundary condition: true
initial concentration: NaN
name: ACMSD
is encoded by: hsa:130013
type: Species
is: SBO:0000252

metaR RE2292C
notes: GENE_ASSOCIATION: SUBSYSTEM: Valine, leucine, and isoleucine metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:6434570,PMID:6688766 NOTES:
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/6434570
fast: false
name: RE2292
is: SBO:0000176
reversible: true
is described by: http://identifiers.org/pubmed/6688766
reactant: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_7a4f4c03_2c21_4e94_abdb_619f10c325d3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7899e534_7769_4e56_8bea_f050abcd0765
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f6531b59_6232_4dbb_bffc_6785fa6dca08
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX tdcrn
reactant: MODEL1109130000#
notes: SUBSYSTEM: Exchange/demand reaction Confidence Level: 1 AUTHORS: EC Number: NOTES: GENE_ASSOCIATION:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for myristoyl carnitine
type: Reaction

metaM cholp g
type: Species
initial amount: NaN
constant: false
is: CHEBI:295975
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C5H13NO4P CHARGE: -1 INCHI: InChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)/p-1 HEPATONET_1.0_ABBREVIATION: HC00442 EHMN_ABBREVIATION: C00588
is: C00588
has only substance units: false
name: choline phosphate(1-)
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#a8ea4bd1_90be_413b_a9dd_2b5f96b0b5c8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_829b460a_e2d4_49e6_b5b9_0d75ab73ea0a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_415f22eb_c37e_4843_81d1_b600bdfbe16a
initial amount: NaN
initial concentration: NaN
constant: false
is: SBO:0000252
name: _AI620219_1_e
is encoded by: hsa:AI620219
has only substance units: false
type: Species
boundary condition: true

metaR r2109
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
type: Reaction
modifier: MODEL1109130000#
fast: false
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: true
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is described by: http://identifiers.org/pubmed/12739169
is: SBO:0000185

metaR r1394
is described by: http://identifiers.org/pubmed/1735445
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/6361812
is described by: http://identifiers.org/pubmed/1988962
type: Reaction
is described by: http://identifiers.org/pubmed/7892212
is version of: http://identifiers.org/ec-code/2.3.1.21
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 0 AUTHORS: PMID:1735445,PMID:1988962,PMID:2355017,PMID:6361812,PMID:7892212 NOTES:
reversible: false
fast: false
name: EC:2.3.1.21
is described by: http://identifiers.org/pubmed/2355017
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_24944eab_9a71_4374_8f1a_70b58a7b4601
value: 0.0
type: LocalParameter

metaM C06199 c
type: Species
notes: FORMULA: C10H16NO CHARGE: 1 INCHI: InChI=1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3 EHMN_ABBREVIATION: C06199
initial amount: NaN
constant: false
is: CHEBI:5764
is: SBO:0000247
initial concentration: 1.0
is: HMDB04366
name: Hordenine
boundary condition: false
has only substance units: false

metaM adpac c
is: HMDB00448
initial amount: NaN
has only substance units: false
type: Species
name: adipic acid
is: SBO:0000247
constant: false
boundary condition: false
initial concentration: 1.0
notes: FORMULA: C6H8O4 CHARGE: -2

http://identifiers.org/biomodels.db/MODEL1109130000#d7abbf1b_b83d_477d_b797_70613c2a3232
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_95fd7a9c_b538_4a60_a26b_d211207ed2e9
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1395
is described by: http://identifiers.org/pubmed/1988962
name: carnitine acetyltransferase EC:2.3.1.7
is described by: http://identifiers.org/pubmed/2355017
type: Reaction
is described by: http://identifiers.org/pubmed/7892212
is described by: http://identifiers.org/pubmed/6361812
is: SBO:0000176
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1735445
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.7 Confidence Level: 0 AUTHORS: PMID:1735445,PMID:1988962,PMID:2355017,PMID:6361812,PMID:7892212 NOTES:
is version of: http://identifiers.org/ec-code/2.3.1.7
product: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#bb619b0d_5c4b_412d_8694_94981b1b4e52
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf3d9413_7d60_4c86_9eb8_e2f4173131a1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_92072e81_b912_4bce_85ce_840eec6b9bab
units: dimensionless
value: 0.0
type: LocalParameter

metaR DHCR242r
notes: GENE_ASSOCIATION: 1718.1 SUBSYSTEM: Cholesterol metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:17984220,PMID:19520779,PMID:19520780 NOTES: lanosterol -> cholesterol pathway FAD known to be cofactor, other details missing NJ
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/17984220
type: Reaction
name: 24-dehydrocholesterol reductase [Precursor]
reversible: false
fast: false
is version of: ECO:0000134
is described by: http://identifiers.org/pubmed/19520780
is described by: http://identifiers.org/pubmed/19520779
product: MODEL1109130000#
is: SBO:0000176
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_6ea39f8b_9d62_448e_aced_b87bf79e194b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0941ba15_d8a3_4d9b_8fc8_93d33a08a111
initial concentration: NaN
constant: true
type: Species
is encoded by: hsa:122970
boundary condition: true
initial amount: NaN
is: Q8N9L9
is: SBO:0000252
name: ACOT4
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_266708fe_5a54_4c3a_904f_34c816c07c29
has only substance units: false
is encoded by: hsa:5333
constant: false
type: Species
name: PLCD1
is: P51178
initial amount: NaN
initial concentration: NaN
is: SBO:0000252
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_ecf0f67a_2d3b_48d5_b129_e54c2d694215
has only substance units: false
is: D3DX95
constant: false
type: Species
name: CHAT
is encoded by: hsa:1103
initial concentration: NaN
is: SBO:0000252
boundary condition: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_14aaeb48_26c0_4ee5_846a_d6be0d56f45d
value: 1000.0
type: LocalParameter

metaR Htx
reactant: MODEL1109130000#
reversible: true
product: MODEL1109130000#
is version of: ECO:0000000
name: H transporter, peroxisome
is: SBO:0000185
type: Reaction
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 0 AUTHORS: NOTES: diffusion NJ

metaR CO2tm
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 4 AUTHORS: PMID:3081508 NOTES: IF
is described by: http://identifiers.org/pubmed/3081508
name: CO2 transport (diffusion), mitochondrial
fast: false
type: Reaction
is: SBO:0000185
reversible: true
reactant: MODEL1109130000#
product: MODEL1109130000#
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_74e43e4e_6a3d_4542_9684_e90beb9ce993
is: SBO:0000252
initial amount: NaN
constant: false
type: Species
has only substance units: false
is encoded by: hsa:126328
initial concentration: NaN
is: C9JT23
boundary condition: true
name: NDUFA11

http://identifiers.org/biomodels.db/MODEL1109130000#_3cab8952_0b99_49d9_95e9_fadeccdb6efc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a53396c5_6410_4fef_b5dd_4efbc6bfa9be
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b2c3c40b_6f0a_47fb_a7f4_893f218c2f1b
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B1:ATP6V1C1:ATP6V1E1:ATP6V1G2:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#aa807d1f_88dc_4251_bb28_a21c5b415538
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b8590201_2b40_487f_8684_ad7ab4498259
value: -1000.0
type: LocalParameter

metaR r1396
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/12133002
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.3.1.21
is described by: http://identifiers.org/pubmed/4475632
reversible: false
name: EC:2.3.1.21
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/5810070

http://identifiers.org/biomodels.db/MODEL1109130000#_9fba84cf_5a6f_4a20_b7dd_7c8038c2f313
value: 0.0
type: LocalParameter

metaM ppi x
boundary condition: false
is: HMDB00250
has only substance units: false
notes: FORMULA: HO7P2 CHARGE: -3 HEPATONET_1.0_ABBREVIATION: HC00023 EHMN_ABBREVIATION: C00013 INCHI: InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3
is: C00013
is: CHEBI:33019
constant: false
name: Diphosphate
initial concentration: 1.0
initial amount: NaN
type: Species
is: SBO:0000247

metaR EX 3ivcrn
reactant: MODEL1109130000#
notes: SUBSYSTEM: Exchange/demand reaction Confidence Level: 1 AUTHORS: EC Number: NOTES: GENE_ASSOCIATION:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for 3-hydroxy-isovaleryl carnitine
type: Reaction

metaR SMPD4
is version of: ECO:0000000
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Sphingolipid metabolism EC Number: Confidence Level: 2 AUTHORS: PMID:12069827,PMID:9972865 NOTES: reaction details not determined - elucidated from PMID: 9972865, 12069827 NJ
reversible: false
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/12069827
is: SBO:0000176
name: sphingomyelinase
is described by: http://identifiers.org/pubmed/9972865
fast: false

metaM cholp l
is: C00588
initial concentration: 1.0
boundary condition: false
constant: false
has only substance units: false
initial amount: NaN
is: SBO:0000247
notes: FORMULA: C5H13NO4P CHARGE: -1 INCHI: InChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)/p-1 HEPATONET_1.0_ABBREVIATION: HC00442 EHMN_ABBREVIATION: C00588
is: CHEBI:295975
name: choline phosphate(1-)
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_63ab5118_6801_4bd1_8886_9db6ad30141e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6c523b65_c267_4dc6_9836_f3211334577d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ddeb5387_6773_45fb_a9eb_1f7e042daa55
has only substance units: false
is: SBO:0000252
constant: false
type: Species
initial amount: NaN
initial concentration: NaN
name: TRDMT1
is encoded by: hsa:1787
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_67283195_5c16_4516_920d_b82b551e78ac
notes: DRUGBANK_UNKNOWN: DB00129, DB01983, DB02381, DB02499, DB02689, DB03144, DB03731, DB03904, DB04197, DB04530, DB04585, DB04648
boundary condition: true
is encoded by: hsa:383
initial amount: NaN
name: ARG1
is: SBO:0000252
initial concentration: NaN
has only substance units: false
constant: false
type: Species
is: P05089

http://identifiers.org/biomodels.db/MODEL1109130000#a83e1a9e_fee5_4cfa_9799_620fde9e1b37
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_664e49c5_35a3_40f7_8475_8049f983075d
value: 0.0
type: LocalParameter

metaR r1397
is described by: http://identifiers.org/pubmed/5810070
is version of: http://identifiers.org/ec-code/2.3.1.7
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.7 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:
name: carnitine acetyltransferase EC:2.3.1.7
is: SBO:0000176
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12133002
is described by: http://identifiers.org/pubmed/4475632
reversible: false
fast: false
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_29043601_40da_467c_a0e9_15887e6c9330
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e3e7edbe_306e_462b_bb69_ca9d6698f49c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8cc495e8_d2e7_4a58_9b44_0ad6dcd33fcc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be8038d9_51f0_4b3f_a41e_0b4b69a2a67b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_30e3e365_2dad_4340_8c95_a441e64d83f2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b978c9be_013b_4e85_ae70_d27950a5d517
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4c08faaa_9a8e_480d_bfea_f5a1b474bc38
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3d6e417d_c75b_4d9f_a5f6_d91816711b3e
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE1262 c
initial amount: NaN
initial concentration: 1.0
has only substance units: false
boundary condition: false
is: SBO:0000247
notes: FORMULA: C12H14N2O6S CHARGE: 0 INCHI: EHMN_ABBREVIATION: CE1262
type: Species
constant: false
name: 5-(S-L-cysteinyl)-dopaquinone

http://identifiers.org/biomodels.db/MODEL1109130000#_0983e598_f01d_4bcd_ae64_c87ac4064e9a
value: 0.0
type: LocalParameter

metaR r1398
reactant: MODEL1109130000#
fast: false
type: Reaction
product: MODEL1109130000#
reversible: false
is: SBO:0000176
is described by: http://identifiers.org/pubmed/4475632
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:
is described by: http://identifiers.org/pubmed/5810070
is version of: http://identifiers.org/ec-code/2.3.1.21
is described by: http://identifiers.org/pubmed/12133002
name: EC:2.3.1.21

http://identifiers.org/biomodels.db/MODEL1109130000#_5a688128_2a1f_4419_8815_389359867ec8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a9f89fa_789b_4528_a526_ebcf3b26e475
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_81f8a18c_2879_4ef4_a6c0_944a73e25751
value: -1000.0
type: LocalParameter

metaR EX idour LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: Exchange of L-iduronate
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_1e6ae73a_f5a7_4187_ba7a_b14429141c19
units: dimensionless
value: 0.0
type: LocalParameter

metaR r2104
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
type: Reaction
reversible: true
modifier: MODEL1109130000#
fast: false
product: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is: SBO:0000185
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

metaR G14T12g
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.38
name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi
is described by: http://identifiers.org/pubmed/12512857
fast: false
is: SBO:0000176
is version of: ECO:0000000
notes: GENE_ASSOCIATION: (8703.1) or (2683.1) or (8704.2) or (8704.1) or (9334.1) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.1.38 Confidence Level: 4 AUTHORS: PMID:12512857,PMID:1903938,PMID:3094506,PMID:3144273,PMID:9405390,PMID:9435216 NOTES: Keratan sulfate I biosynthesis NCD
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9435216
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/9405390
is described by: http://identifiers.org/pubmed/3144273
is described by: http://identifiers.org/pubmed/1903938
is described by: http://identifiers.org/pubmed/3094506
reversible: false

metaM acmana c
has only substance units: false
constant: false
is: HMDB01129
is: SBO:0000247
name: N-acetyl-D-mannosamine
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C8H15NO6 CHARGE: 0 INCHI: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6-,7-,8-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00474 EHMN_ABBREVIATION: C00645
boundary condition: false
type: Species
is: CHEBI:17122

http://identifiers.org/biomodels.db/MODEL1109130000#db218d08_eb2e_47f9_8909_a89cec6d5250
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1f6ed335_7d79_411e_a9fe_00eccb64fec0
units: dimensionless
value: 0.0
type: LocalParameter

metaM ppi m
is: C00013
initial amount: NaN
boundary condition: false
is: SBO:0000247
notes: FORMULA: HO7P2 CHARGE: -3 HEPATONET_1.0_ABBREVIATION: HC00023 EHMN_ABBREVIATION: C00013 INCHI: InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3
constant: false
has only substance units: false
is: HMDB00250
name: Diphosphate
type: Species
is: CHEBI:33019
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#cd044955_4fce_45a5_a111_06de7f22bff2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_bc84112d_2178_4bab_a5e4_8fc2c81e05c8
is: O75828
is encoded by: hsa:874
boundary condition: true
has only substance units: false
initial concentration: NaN
is: SBO:0000252
initial amount: NaN
constant: true
name: CBR3
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_01dab791_7ed2_4ae7_992a_90395a1dc14f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_07292b2c_4419_49b7_a723_17b1ffd212e6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_f47384ca_2c8f_4152_83d6_eade0806c8b2
has part: Q86TM7
is encoded by: hsa:8818
is encoded by: hsa:8813
type: Species
constant: false
name: DPM3:DPM1:DPM2
has part: O60762
is encoded by: hsa:54344
has part: O94777
is: SBO:0000297
has only substance units: false
initial amount: NaN
initial concentration: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_124bf11f_5c7e_4f3f_a8f3_5de4c26965c9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7ebd3f0e_0169_47f4_95fa_c19aba4202d5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_525fc68b_1390_4bad_9cf9_f58732ba6e32
value: 1000.0
type: LocalParameter

metaR r2103
reactant: MODEL1109130000#
reversible: true
is: SBO:0000185
type: Reaction
product: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
fast: false
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#df53199c_9df5_4f7d_9fc7_cc31ccb03e14
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e9fc41c2_b454_4944_8506_c254f35ddb3c
units: dimensionless
value: 0.0
type: LocalParameter

metaR HMGCOAtx
product: MODEL1109130000#
fast: false
name: Hydroxymethylglutaryl-CoA reversible peroxisomal transport
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 2 AUTHORS: PMID:14713247 NOTES: diffusion NJ
reactant: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/14713247
reversible: true
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#dc477000_6f95_4ea0_bbc6_2997ecbb0708
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5b3dcef4_0a7b_4569_86cb_086b5ec62abd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3a20d4d6_6d1b_4fd1_b461_6a413613232f
value: 0.0
type: LocalParameter

metaM acmana e
is: SBO:0000247
has only substance units: false
notes: FORMULA: C8H15NO6 CHARGE: 0 INCHI: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6-,7-,8-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00474 EHMN_ABBREVIATION: C00645
boundary condition: false
name: N-acetyl-D-mannosamine
initial concentration: 1.0
type: Species
is: CHEBI:17122
is: HMDB01129
initial amount: NaN
constant: false

metaR CYSTLEUrBATtc
is described by: http://identifiers.org/pubmed/19184091
reversible: false
type: Reaction
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10958334
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 10958334, PMID: 19184091, PMID: 18195088, PMID: 11546643 EC Number: NOTES: sodium independant antiport transport system, exchanges di-basic amino acids into the cells and neutral amino acids out of the cell. Located on the apical surfaces of transporting epithelia. Cellular localization being small intestine, kidney (proximal tubule), lung, placenta, brain and thymus. Requires the heterodimerization with rBAT glycoprotein. (PMID: 10958334). GENE_ASSOCIATION: (11136.1 and 6519.1)
name: transport of L-Cystine into the cell in exchange for L-Leucine by b0,+AT transporter at the apical surfaces of the membranes of small intestine and renal cells.
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11546643
fast: false
is: SBO:0000185
is described by: http://identifiers.org/pubmed/18195088

metaM whhdca c
boundary condition: false
has only substance units: false
is: SBO:0000247
notes: FORMULA: C16H31O3 CHARGE: -1 INCHI: InChI=1/C16H32O3/c17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(18)19/h17H,1-15H2,(H,18,19)/p-1
initial amount: NaN
type: Species
is: HMDB06294
constant: false
initial concentration: 1.0
name: omega hydroxy hexadecanoate (n-C16:0)

http://identifiers.org/biomodels.db/MODEL1109130000#_96a4601f_507a_4012_8b82_5d295bd7db15
units: dimensionless
value: 0.0
type: LocalParameter

metaR r2102
modifier: MODEL1109130000#
reactant: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/12739169
type: Reaction
fast: false
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is: SBO:0000185

metaR EX HC01361 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Exchange of Dihydroneopterin
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_36db4279_3b25_4552_abb5_a81aabafec46
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_76da9d7e_cf03_4790_ba93_fc5973f6054a
type: Species
has only substance units: false
has part: P53597
initial amount: NaN
initial concentration: NaN
is: SBO:0000297
is encoded by: hsa:8801
boundary condition: true
is encoded by: hsa:8802
constant: false
notes: DRUGBANK_UNKNOWN: DB00139
has part: Q96I99
name: SUCLG2:SUCLG1

http://identifiers.org/biomodels.db/MODEL1109130000#_4acf60ea_cc5d_4065_be96_58c4c6ac3af3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_12316c69_03e1_4b5b_a571_73f827eb07f9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_12ea4d35_c0df_4a1a_b699_ce1eef733036
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24809576_32e7_4a69_9f08_5df46dda4235
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b3c5c4a4_bbbc_4513_bc02_7475c10acd88
is encoded by: hsa:4259
is: SBO:0000252
boundary condition: true
initial amount: NaN
type: Species
name: MGST3
initial concentration: NaN
has only substance units: false
constant: true
is: O14880

metaR GLACOm
type: Reaction
notes: GENE_ASSOCIATION: (8659.2) or (217.1) or (8659.1) or (219.1) SUBSYSTEM: Vitamin C metabolism EC Number: 1.5.1.12 Confidence Level: 1 AUTHORS: PMID:3779687 NOTES: NCD
modifier: MODEL1109130000#
is version of: ECO:0000212
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: false
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.5.1.12
name: D-Glucuronolactone:NAD+ oxidoreductase, mitochondrial
is described by: http://identifiers.org/pubmed/3779687
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3c8cba6f_0a0c_4a10_8dec_2534e6d01b18
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a94dc2bd_c69b_4731_bb2c_a87c0ae66ba1
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3d2f00b5_de20_4a45_8f7c_22029bb3de73
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b4c463b0_02d7_401a_be98_483f6bef5b9c
value: 0.0
type: LocalParameter

metaR CO2tg
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, golgi apparatus EC Number: Confidence Level: 1 AUTHORS: NOTES: NCD
reversible: true
product: MODEL1109130000#
is: SBO:0000185
reactant: MODEL1109130000#
is version of: ECO:0000000
name: CO2 Golgi transport
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_56ee4c8b_d092_4258_b957_9274f05946b6
value: 0.0
type: LocalParameter

metaR r2101
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is described by: http://identifiers.org/pubmed/12739169
is: SBO:0000185
type: Reaction
product: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
reversible: true
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_14479782_9263_49a8_a625_b91e63c30fb2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7215cdb0_ebbd_4108_985c_33b191718c93
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1c613403_71fc_4672_b1fd_a024572f0fa8
value: 0.0
type: LocalParameter

metaM ppi n
is: CHEBI:33019
notes: FORMULA: HO7P2 CHARGE: -3 INCHI: InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 HEPATONET_1.0_ABBREVIATION: HC00023 EHMN_ABBREVIATION: C00013
initial amount: NaN
is: HMDB00250
name: diphosphate(3-)
type: Species
has only substance units: false
boundary condition: false
is: SBO:0000247
initial concentration: 1.0
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#d9dcb29b_2c43_4dda_b427_30907e3612a8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f01b7621_887e_487c_a25d_3505a3964562
value: -1000.0
type: LocalParameter

metaR 3SALACBOXL
type: Reaction
is: SBO:0000176
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/4.1.1.15
product: MODEL1109130000#
reversible: false
fast: false
is version of: ECO:0000269
modifier: MODEL1109130000#
name: 3-Sulfino-L-alanine carboxy-lyase
notes: GENE_ASSOCIATION: (51380.1) or (2571.1) or (2572.1) or (2571.2) SUBSYSTEM: Taurine and hypotaurine metabolism EC Number: 4.1.1.15 Confidence Level: 4 AUTHORS: NOTES: SAB

http://identifiers.org/biomodels.db/MODEL1109130000#_96458b35_32a5_4357_9156_f2e08c8e9941
value: 1000.0
type: LocalParameter

metaM whhdca e
name: omega hydroxy hexadecanoate (n-C16:0)
boundary condition: false
is: SBO:0000247
initial amount: NaN
has only substance units: false
notes: FORMULA: C16H31O3 CHARGE: -1 INCHI: InChI=1/C16H32O3/c17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(18)19/h17H,1-15H2,(H,18,19)/p-1
type: Species
is: HMDB06294
constant: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#c02ef54b_a9c7_4f49_b665_b11d03c1f0eb
units: dimensionless
value: 0.0
type: LocalParameter

metaR r2108
reversible: true
type: Reaction
is: SBO:0000185
reactant: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
fast: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_2fdc61e0_f81e_4746_8d4d_dcbd3f2ad44c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8b144812_9460_4d01_aa56_44f1ece01626
type: Species
boundary condition: true
name: CYP1A1
constant: false
initial amount: NaN
is: SBO:0000252
is: A0N0X8
is encoded by: hsa:1543
initial concentration: NaN
has only substance units: false

metaM C06199 l
constant: false
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C10H16NO CHARGE: 1 INCHI: InChI=1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3 EHMN_ABBREVIATION: C06199
name: Hordenine
initial amount: NaN
has only substance units: false
is: SBO:0000247
is: HMDB04366
is: CHEBI:5764
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_4ebca683_4ef2_44fd_a9e2_482fc7092a98
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4e7bbbf2_c82a_4151_ae6a_4a3d6bff8747
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7795282d_cf72_4327_b6c6_487809751469
name: PPAP2B
is: O14495
has only substance units: false
initial amount: NaN
constant: false
type: Species
boundary condition: true
initial concentration: NaN
is: SBO:0000252
is encoded by: hsa:8613

http://identifiers.org/biomodels.db/MODEL1109130000#_297b9e04_f9f9_40a7_8f4f_608bcf7d1488
name: ALDH7A1
initial amount: NaN
initial concentration: NaN
is: E7EPT3
is: SBO:0000252
is encoded by: hsa:501
has only substance units: false
type: Species
boundary condition: true
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_7fb2e97b_a952_4704_91f2_32cf4d266792
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e66229d2_9787_4727_98b1_797604339b08
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_623a1b45_f43e_42d3_bcaa_1add058d2cc0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31b15301_0d05_4430_9d9c_055b883197d3
value: 1000.0
type: LocalParameter

metaR r2107
modifier: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
fast: false
reactant: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
product: MODEL1109130000#
is: SBO:0000185
reversible: true
is described by: http://identifiers.org/pubmed/12739169

http://identifiers.org/biomodels.db/MODEL1109130000#_47d6de02_eb83_4f91_9297_6b35db7966e4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f692f6de_def3_4c62_82ab_59fff289aebc
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1c4316d3_a296_40ca_9812_f6cefa400d77
has only substance units: false
initial concentration: NaN
is: SBO:0000252
type: Species
constant: false
initial amount: NaN
is encoded by: hsa:10861
name: SLC26A1
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_6c10ad4c_d22e_4153_bf00_323ef935476a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ba18744a_f8b6_44e4_9d05_97fe014ef441
is: P14550
is: SBO:0000252
name: AKR1A1
type: Species
initial amount: NaN
constant: false
is encoded by: hsa:10327
boundary condition: true
initial concentration: NaN
has only substance units: false

metaM hexccoa m
has only substance units: false
name: Hexacosanoyl-CoA (n-C26:0CoA)
initial concentration: 1.0
initial amount: NaN
constant: false
type: Species
notes: FORMULA: C47H82N7O17P3S CHARGE: -4 INCHI: InChI=1/C47H86N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-38(56)75-31-30-49-37(55)28-29-50-45(59)42(58)47(2,3)33-68-74(65,66)71-73(63,64)67-32-36-41(70-72(60,61)62)40(57)46(69-36)54-35-53-39-43(48)51-34-52-44(39)54/h34-36,40-42,46,57-58H,4-33H2,1-3H3,(H,49,55)(H,50,59)(H,63,64)(H,65,66)(H2,48,51,52)(H2,60,61,62)/p-4/t36-,40-,41-,42+,46-/m1/s1
boundary condition: false
is: SBO:0000247
is: HMDB06459

http://identifiers.org/biomodels.db/MODEL1109130000#c01b3d15_90df_41e3_9609_42885d934cfa
units: dimensionless
value: 0.0
type: LocalParameter

metaR FOLTle
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 3 AUTHORS: G.F.M. Ball (2006) Vitamins their role in the human body, Blackwell publishing, chapter 17, page 353, PMID: 19762432. EC Number: NOTES: carrier protein mediated. H+ symport. Mutations in this gene is associated with hereditary folate mal-absorption syndrome (IEM) (PMID: 19762432) . GENE_ASSOCIATION: 113235.1
fast: false
name: folate uptake into the enterocytes
is: SBO:0000185
modifier: MODEL1109130000#
type: Reaction
reversible: false

metaM CE5591 r
boundary condition: false
is: SBO:0000247
type: Species
name: 4-OH-13-cis-retinal
notes: FORMULA: C20H28O2 CHARGE: 0 INCHI: EHMN_ABBREVIATION: CE5591
has only substance units: false
initial concentration: 1.0
constant: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_41cbd627_42cb_4fd4_83c6_fa4ee6317d38
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0e628078_0c41_43c5_95e4_a5620693a5b5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a59696f1_d3d1_4ec7_b27c_20eea9ca7e7f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf660208_65a5_4f29_b78c_0b2c4eaa42fc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_44ed92ea_9782_4c2b_8387_56877f3f6d3d
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_24fb0d4f_1179_4236_acc1_a1863e9b181b
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX tag hs LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: triacylglycerol (homo sapiens) exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#a01b23be_ad00_4658_ae25_34929fcae908
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b6a160d8_287f_4b19_a47c_3a54676b968b
value: 0.0
type: LocalParameter

metaR r2106
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
type: Reaction
is: SBO:0000185
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
product: MODEL1109130000#
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_33da202f_92cb_4de8_886f_c81d6f115fb7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_728d1c3a_95a4_423c_ae6b_1e86b83c96fd
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f0846479_69e8_400e_ae6f_5ba42eb6bfb2
value: 1000.0
type: LocalParameter

metaM cholp c
is: CHEBI:295975
name: choline phosphate(1-)
is: SBO:0000247
constant: false
has only substance units: false
initial concentration: 1.0
notes: FORMULA: C5H13NO4P CHARGE: -1 INCHI: InChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)/p-1 HEPATONET_1.0_ABBREVIATION: HC00442 EHMN_ABBREVIATION: C00588
boundary condition: false
initial amount: NaN
type: Species

metaR RE2150C
product: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8295481
fast: false
modifier: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Vitamin A metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:8295481 NOTES:
reversible: false
is version of: http://identifiers.org/ec-code/2.4.1.17
name: RE2150

http://identifiers.org/biomodels.db/MODEL1109130000#c25232cd_7671_4878_aa96_ee5893d80496
units: dimensionless
value: 0.0
type: LocalParameter

metaR PE HStm
is version of: ECO:0000000
product: MODEL1109130000#
fast: false
reactant: MODEL1109130000#
name: phosphatidylethanolamine scramblase
is: SBO:0000185
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 1 AUTHORS: NOTES:
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_690a07cf_b40f_4e8e_b63e_bfb4d2aaa341
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8946cc14_76bc_4865_b958_8f51226eba08
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d7b1c18a_20cf_4fc7_940c_0c53ebecf37f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_50fa8ccc_91d3_4b45_9234_89e6d8ee49c5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1c4f09bf_0984_4702_afcb_3ea7215a16c4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6e9f80a4_5a46_48ee_abdd_373f3c038a03
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a5946603_3749_40ff_a31e_8ca2d6f85ab9
boundary condition: true
initial concentration: NaN
is: SBO:0000252
is encoded by: hsa:586
initial amount: NaN
is: P54687
name: BCAT1
has only substance units: false
type: Species
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_959793fe_0df5_47d5_a955_a0e7019b35b5
value: 0.0
type: LocalParameter

metaR GLCAASE9ly
is described by: http://identifiers.org/pubmed/3987656
type: Reaction
is described by: http://identifiers.org/pubmed/3468507
reversible: false
is described by: http://identifiers.org/pubmed/3924735
is version of: http://identifiers.org/ec-code/3.2.1.31
name: beta-glucuronidase, lysosomal
fast: false
notes: GENE_ASSOCIATION: 2990.1 SUBSYSTEM: Hyaluronan metabolism EC Number: 3.2.1.31 Confidence Level: 4 AUTHORS: PMID:3468507,PMID:3924735,PMID:3987656 NOTES: NCD
is version of: ECO:0000269
reactant: MODEL1109130000#
is: SBO:0000176
product: MODEL1109130000#
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_9da82f15_b528_43b8_8ecf_6553f18e849b
value: 1000.0
type: LocalParameter

metaM ocde9ecoa x
has only substance units: false
constant: false
initial concentration: 1.0
is: SBO:0000247
boundary condition: false
type: Species
is: http://identifiers.org/pubchem.substance/5280355
notes: FORMULA: C39H64N7O17P3S CHARGE: -4
name: 9-octadecenoylcoa
initial amount: NaN

metaR r2105
reversible: true
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
fast: false
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#b695ce53_1315_46cf_a0e4_dba97e6d4ebb
units: dimensionless
value: 0.0
type: LocalParameter

metaM ppi r
name: Diphosphate
is: C00013
is: SBO:0000247
constant: false
initial concentration: 1.0
notes: FORMULA: HO7P2 CHARGE: -3 HEPATONET_1.0_ABBREVIATION: HC00023 EHMN_ABBREVIATION: C00013 INCHI: InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3
has only substance units: false
is: HMDB00250
boundary condition: false
type: Species
is: CHEBI:33019
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_82ce4945_741e_41c8_99c8_238698b64cdc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d9d407ea_16f9_4fdc_a8af_dd3a44f8bc10
initial amount: NaN
initial concentration: NaN
is encoded by: hsa:23600
name: AMACR
is: Q9UHK6
has only substance units: false
is: SBO:0000252
boundary condition: true
constant: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#f6c98afc_c165_4136_ab16_8ec965e71f11
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_81fab36b_f0eb_4c6b_978a_8967c81107a7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_46e116a0_0a17_4084_a4b5_689beabf3d7a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e38b6412_8a11_4ad4_9b63_b5fb980087b3
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_05a484c2_a5ce_4610_83ff_13f914f27d7d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_862765f9_b257_4cc9_abbb_75f15cd0ae3b
boundary condition: true
initial concentration: NaN
type: Species
has only substance units: false
initial amount: NaN
constant: true
name: CYP2C8
is: P10632
is encoded by: hsa:1558
is: SBO:0000252

metaR ACCOACm
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
is: SBO:0000176
modifier: MODEL1109130000#
name: Acetyl-Coa carboxylase, beta isoform
is described by: http://identifiers.org/pubmed/10677481
type: Reaction
reversible: false
is version of: http://identifiers.org/ec-code/6.4.1.2
notes: GENE_ASSOCIATION: 32.1 SUBSYSTEM: Fatty acid oxidation EC Number: 6.4.1.2 Confidence Level: 4 AUTHORS: PMID:10677481 NOTES: TDV (9/14/2004)
is version of: ECO:0000269

http://identifiers.org/biomodels.db/MODEL1109130000#_822574ef_c0f0_4dd5_b2ca_2b54b0a52e0a
value: 0.0
type: LocalParameter

metaR r0718
product: MODEL1109130000#
name: (S)-3-Hydroxytetradecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
type: Reaction
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8687463
is described by: http://identifiers.org/pubmed/7150615
is described by: http://identifiers.org/pubmed/1550553
is described by: http://identifiers.org/pubmed/1651711
is described by: http://identifiers.org/pubmed/10329704
reversible: false
is version of: http://identifiers.org/ec-code/1.1.1.35
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8188243
is described by: http://identifiers.org/pubmed/10231530
notes: GENE_ASSOCIATION: 80270.1 SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
fast: false
is described by: http://identifiers.org/pubmed/9553139

metaR PYAM5Ptm
is version of: ECO:0000000
reactant: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/6263901
is: SBO:0000185
reversible: true
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/7174673
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 2 AUTHORS: PMID:6263901,PMID:7174673 NOTES: IT
name: Pyridoxamine 5-phosphate transport via diffusion, mitochondrial

http://identifiers.org/biomodels.db/MODEL1109130000#_6782fd61_61fb_498f_a819_83a75df3b1d0
has only substance units: false
name: ABCB4
initial amount: NaN
type: Species
boundary condition: true
is: P21439
is encoded by: hsa:5244
is: SBO:0000252
initial concentration: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3af8b50d_0bab_4d68_9454_244fc42cadfc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1a2b67ae_aa0b_4cc3_9878_b4afad814d3b
type: Species
name: SLC6A9
initial concentration: NaN
is: P48067
is: SBO:0000252
is encoded by: hsa:6536
constant: false
boundary condition: true
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_1c8f9760_3835_494a_bd73_beab00dcc091
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fb0b82c4_bdfa_4717_9017_33e6806b5cab
value: 1000.0
type: LocalParameter

metaR EX triodthysuf LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Triiodothyronine sulfate exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_627002be_29ad_45cc_b46e_ae88befb99cf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_713afbaa_e073_45c1_8bd8_b47252ac3ec3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a6555b2_fadf_4080_8bb5_e71f9cef369a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b2eafc14_3441_47e6_a754_04c5721a21d3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d08437a3_8fd3_4345_94af_528fc2d84bff
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_cf6d5ea6_bfd9_4acd_af24_c80f992848e0
type: Species
is: SBO:0000252
is encoded by: hsa:51447
constant: true
initial concentration: NaN
name: IP6K2
has only substance units: false
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_1f067a01_2af3_4021_89de_3cac44bcee03
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5c79a59d_1eec_41f8_aeff_c2f9f1dc7088
type: Species
name: INPP5D
is: Q92835
initial concentration: NaN
has only substance units: false
is encoded by: hsa:3635
initial amount: NaN
is: SBO:0000252
boundary condition: true
constant: true

metaR r0717
is version of: http://identifiers.org/ec-code/4.2.1.17
product: MODEL1109130000#
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
type: Reaction
fast: false
reactant: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8012501
name: (S)-3-Hydroxyhexadecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
is described by: http://identifiers.org/pubmed/8188243

http://identifiers.org/biomodels.db/MODEL1109130000#c8c29a5f_0ffa_4a7c_acd3_d83413e1c17f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#feb0f6b6_08fd_4b7c_9c11_de5eb1f17410
value: 1000.0
type: LocalParameter

metaR CSPG Et
reversible: false
is: SBO:0000185
product: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES:
name: chondroitin sulfate E transport, golgi to extracellular
is version of: ECO:0000000
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#c14c0e0e_5a65_4a73_959a_3eead2a36ced
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0d547fec_749e_438e_b622_3ed5b0aca980
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2fa64359_6926_4633_adea_67f9e461ea10
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c84b90ed_bb16_453a_a1ed_d3b92cc8561a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7c315a3b_bf57_425a_8a69_6bd14e033c41
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2de5bdf_a3d2_4027_bf74_72c52af3a68f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9808a022_ed64_4d20_9210_7b039a5d056b
units: dimensionless
value: 0.0
type: LocalParameter

metaM 44mctr r
name: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
is: HMDB01023
has only substance units: false
initial concentration: 1.0
constant: false
initial amount: NaN
is: CHEBI:17813
is: SBO:0000247
boundary condition: false
type: Species
notes: FORMULA: C29H46O CHARGE: 0 INCHI: InChI=1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC01808 EHMN_ABBREVIATION: C11455

http://identifiers.org/biomodels.db/MODEL1109130000#_07094ce5_72e4_4261_89f1_b8e001d3982b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2ace4534_207e_4c3b_bbd7_5cb3eea24132
units: dimensionless
value: 0.0
type: LocalParameter

metaR RBK
is: SBO:0000176
reversible: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 64080.1 SUBSYSTEM: Pentose phosphate pathway EC Number: Confidence Level: 2 AUTHORS: NOTES:
type: Reaction
product: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
is version of: ECO:0000304
name: ribokinase

http://identifiers.org/biomodels.db/MODEL1109130000#_7551b5c4_ae05_4755_8a8b_99c80b8d930b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_09903b35_952d_4ca8_b44b_c87f9606f883
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_01a5e5d7_4a42_485d_8e87_0fe8f0a56b02
value: 0.0
type: LocalParameter

metaR r0716
product: MODEL1109130000#
fast: false
is: SBO:0000176
is version of: http://identifiers.org/ec-code/4.2.1.17
is described by: http://identifiers.org/pubmed/8188243
type: Reaction
name: (S)-3-Hydroxyhexadecanoyl-CoA hydro-lyase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:4.2.1.17
is described by: http://identifiers.org/pubmed/8012501
notes: GENE_ASSOCIATION: SUBSYSTEM: Unassigned EC Number: 4.2.1.17 Confidence Level: 0 AUTHORS: PMID:8012501,PMID:8188243 NOTES:
reactant: MODEL1109130000#
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#d25a136f_757a_4270_a199_92299a3c5103
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bb679dbd_2a83_4398_a69e_a277c2f0fee6
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8368c946_4ae7_48a1_b823_d539c779fa5f
constant: true
initial amount: NaN
is encoded by: hsa:10327
is: SBO:0000252
type: Species
initial concentration: NaN
boundary condition: true
has only substance units: false
is: P14550
name: AKR1A1

metaR PETOHMm hs
fast: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.1.1.17
reactant: MODEL1109130000#
type: Reaction
is version of: ECO:0000254
is: SBO:0000176
is described by: http://identifiers.org/pubmed/9989271
name: phosphatidylethanolamine N-methyltransferase
modifier: MODEL1109130000#
reversible: false
notes: GENE_ASSOCIATION: (10400.2) or (10400.1) or (10400.3) SUBSYSTEM: Glycerophospholipid metabolism EC Number: 2.1.1.17 Confidence Level: 2 AUTHORS: PMID:9989271 NOTES: for human Catalyzes three sequential methylation of phosphatidylethanolamine (PE) by AdoMet, thus producing phosphatidylcholine (PC). [Swiss-prot] NJ

http://identifiers.org/biomodels.db/MODEL1109130000#_27095b13_b6b1_4bbf_bb7f_25b84670503a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_007d9582_1398_4a8a_b163_a814ab23401c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_bee44215_f239_46db_b9c7_bd24651b9ea2
has only substance units: false
constant: true
boundary condition: true
type: Species
initial amount: NaN
is encoded by: hsa:T83654
is: SBO:0000252
name: null
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#dc2f97f7_a1f7_4693_921d_c70c92b01df6
value: 1000.0
type: LocalParameter

metaR Htm
reversible: false
product: MODEL1109130000#
fast: false
is: SBO:0000185
name: Uncoupling protein
is described by: http://identifiers.org/pubmed/14598172
reactant: MODEL1109130000#
is version of: ECO:0000269
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (9016.1) or (7352.2) or (7352.1) or (7351.1) or (9016.2) or (7350.1) or (9481.1) SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 4 AUTHORS: PMID:14598172 NOTES: TDV
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_1542a18d_5d2f_453b_a4cd_857bee6ceca8
value: -1000.0
type: LocalParameter

metaR r0715
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7150615
is described by: http://identifiers.org/pubmed/10329704
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9553139
notes: GENE_ASSOCIATION: (AI435857.1) or (79717.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
is version of: http://identifiers.org/ec-code/1.1.1.35
is described by: http://identifiers.org/pubmed/1651711
is described by: http://identifiers.org/pubmed/8687463
reversible: false
is described by: http://identifiers.org/pubmed/1550553
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8188243
type: Reaction
name: (S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
fast: false
is described by: http://identifiers.org/pubmed/10231530

http://identifiers.org/biomodels.db/MODEL1109130000#d1832b4d_62ac_4581_9973_8f99bfc0649b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8091e3f5_db98_4076_8e71_692a9064a602
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4ace9be2_72e4_4ed2_86fc_aac840e642f1
initial amount: NaN
has only substance units: false
boundary condition: true
is: SBO:0000252
is encoded by: hsa:6821
constant: true
type: Species
initial concentration: NaN
name: SUOX
is: P51687

http://identifiers.org/biomodels.db/MODEL1109130000#d5a47726_b3ab_401b_aad2_bdb8baaf85eb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_93f9c42b_ec3a_48f0_b307_4448ad57984f
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#c1493787_948c_4eff_8151_ec06754c38ab
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_117922cb_a02d_41b9_b6e1_badce60db19a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed8ec464_c86b_425e_b71d_5a7bec15675e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e1171983_763b_4304_81b7_0fe8fc4a6556
value: 0.0
type: LocalParameter

metaR THFtm
name: 5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 2 AUTHORS: PMID:11375437 NOTES: NCD
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/11375437
reversible: true
is: SBO:0000185
is version of: ECO:0000000

metaR RE3106R
type: Reaction
modifier: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/10970790
name: RE3106
notes: GENE_ASSOCIATION: 64834.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_16240c09_d82f_417a_8f87_cd9e4299dab9
value: 0.0
type: LocalParameter

metaR r0714
product: MODEL1109130000#
reactant: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/8687463
is described by: http://identifiers.org/pubmed/9553139
is version of: http://identifiers.org/ec-code/1.1.1.35
fast: false
name: (S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7150615
type: Reaction
is described by: http://identifiers.org/pubmed/8188243
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
is described by: http://identifiers.org/pubmed/1651711
is described by: http://identifiers.org/pubmed/10231530
is described by: http://identifiers.org/pubmed/1550553
is described by: http://identifiers.org/pubmed/10329704

http://identifiers.org/biomodels.db/MODEL1109130000#_27bfd22b_c55b_4d17_a090_1560377044c1
units: dimensionless
value: 0.0
type: LocalParameter

metaM orn m
has only substance units: false
constant: false
name: Ornithine
type: Species
notes: FORMULA: C5H13N2O2 CHARGE: 1 INCHI: InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1
initial concentration: 1.0
is: C01602
is: CHEBI:46912
initial amount: NaN
boundary condition: false
is: HMDB00214
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#fa0f7155_358f_4219_94e7_71a8110af323
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_827513f1_3aed_4466_889a_92c8967f5c43
value: 0.0
type: LocalParameter

metaR MM6B1ag
is described by: http://identifiers.org/pubmed/10915796
notes: GENE_ASSOCIATION: (57134.1) or (10905.1) or (4121.1) SUBSYSTEM: N-glycan synthesis EC Number: 3.2.1.113 Confidence Level: 0 AUTHORS: PMID:10915796,PMID:9592125 NOTES: NCD
is version of: ECO:0000000
modifier: MODEL1109130000#
is: SBO:0000176
type: Reaction
reactant: MODEL1109130000#
name: mannosyl-oligosaccharide 1,2-alpha-mannosidase, Golgi apparatus
is described by: http://identifiers.org/pubmed/9592125
is version of: http://identifiers.org/ec-code/3.2.1.113
reversible: false
product: MODEL1109130000#
fast: false

metaR THFtl
is: SBO:0000185
type: Reaction
fast: false
is version of: ECO:0000000
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, lysosomal EC Number: Confidence Level: 2 AUTHORS: PMID:11375437 NOTES: NCD,IT
name: 5,6,7,8-Tetrahydrofolate transport, diffusion, lysosomal
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11375437
reversible: true

metaM hexccoa c
notes: FORMULA: C47H82N7O17P3S CHARGE: -4 INCHI: InChI=1/C47H86N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-38(56)75-31-30-49-37(55)28-29-50-45(59)42(58)47(2,3)33-68-74(65,66)71-73(63,64)67-32-36-41(70-72(60,61)62)40(57)46(69-36)54-35-53-39-43(48)51-34-52-44(39)54/h34-36,40-42,46,57-58H,4-33H2,1-3H3,(H,49,55)(H,50,59)(H,63,64)(H,65,66)(H2,48,51,52)(H2,60,61,62)/p-4/t36-,40-,41-,42+,46-/m1/s1
name: Hexacosanoyl-CoA (n-C26:0CoA)
is: SBO:0000247
type: Species
initial amount: NaN
constant: false
has only substance units: false
boundary condition: false
is: HMDB06459
initial concentration: 1.0

metaR r2110
modifier: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
type: Reaction
reversible: true
reactant: MODEL1109130000#
is: SBO:0000185
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is described by: http://identifiers.org/pubmed/12739169
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#cd06315a_5fb7_4dec_866d_11a96f852555
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eee84d44_03df_4ee4_bec7_19ddf8d03874
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d68805c7_77b7_42ac_8aba_9933fedc4b82
has only substance units: false
initial amount: NaN
boundary condition: true
initial concentration: NaN
is: B2RB47
constant: false
is encoded by: hsa:271
type: Species
name: AMPD2
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#f94f8b7c_39c0_4654_98a8_435194ee424d
value: 0.0
type: LocalParameter

metaR r0713
is described by: http://identifiers.org/pubmed/4452359
name: dodecanoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating) Fatty acid biosynthesis EC:2.3.1.85
reversible: true
is described by: http://identifiers.org/pubmed/6137188
reactant: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7567999
is described by: http://identifiers.org/pubmed/7834997
is described by: http://identifiers.org/pubmed/11750882
is: SBO:0000176
notes: GENE_ASSOCIATION: (1892.1) or (1962.1) or (3030.1) SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:11750882,PMID:4452359,PMID:6137188,PMID:7567999,PMID:7834997,PMID:8962082 NOTES:
type: Reaction
is described by: http://identifiers.org/pubmed/8962082
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.85
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6e9ace46_ef39_4319_99d2_d1eceecf5bd1
value: 0.0
type: LocalParameter

metaR RE3554M
is described by: http://identifiers.org/pubmed/9755286
is version of: http://identifiers.org/ec-code/2.5.1.18
notes: GENE_ASSOCIATION: (2954.1) or (4257.1) or (373156.1) SUBSYSTEM: Eicosanoid metabolism EC Number: 2.5.1.18 Confidence Level: 0 AUTHORS: PMID:9755286 NOTES:
reversible: true
is: SBO:0000176
type: Reaction
reactant: MODEL1109130000#
name: RE3554
product: MODEL1109130000#
modifier: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_64c04d33_22ca_4558_abe4_0d34304554dc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_65486432_d51d_44d2_84ea_af66fa19542a
units: dimensionless
value: 0.0
type: LocalParameter

metaR B3GALT41g
is version of: ECO:0000269
product: MODEL1109130000#
type: Reaction
fast: false
notes: GENE_ASSOCIATION: 8705.1 SUBSYSTEM: Sphingolipid metabolism EC Number: 2.4.1.62 Confidence Level: 4 AUTHORS: NOTES: NJ
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.62
name: Beta-1,3-galactosyltransferase 4
reactant: MODEL1109130000#
is: SBO:0000176
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#db438e13_caf1_45b3_9add_e22b96524148
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a8a33c51_4bec_4dc1_8787_3848cca7aff5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0cf4d3bc_64c6_4ec7_9ec1_f9885de6b5e3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1c15e2af_3ab4_4893_a357_d1907ab7864d
value: 0.0
type: LocalParameter

metaM CE5244 x
name: 4-hydroxyestrone-2-S-glutathione
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: InChI=1/C28H37N3O9S/c1-28-9-8-13-14(17(28)4-6-21(28)32)2-3-15-16(13)10-20(25(37)24(15)36)41-12-19(26(38)30-11-23(34)35)31-22(33)7-5-18(29)27(39)40/h10,13-14,17-19,36-37H,2-9,11-12,29H2,1H3,(H,30,38)(H,31,33)(H,34,35)(H,39,40)/p-1/t13-,14+,17-,18+,19+,28+/m0/s1 EHMN_ABBREVIATION: CE5244
has only substance units: false
initial concentration: 1.0
initial amount: NaN
constant: false
boundary condition: false
type: Species
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_6826fbd8_9083_4763_98e4_82bbd1c8e409
units: dimensionless
value: 0.0
type: LocalParameter

metaR r2111
product: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is: SBO:0000185
is described by: http://identifiers.org/pubmed/12739169
fast: false
type: Reaction
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
reactant: MODEL1109130000#
reversible: true
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_7b08a47a_e80a_4dd2_af29_4776f2bf01b9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a1d758e_a46d_4dc4_b53a_a231c8f0d363
value: -1000.0
type: LocalParameter

metaR r0712
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.85
reversible: true
name: Dodecanoyl-[acyl-carrier protein]: malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Fatty acid biosynthesis EC:2.3.1.85
is: SBO:0000176
notes: GENE_ASSOCIATION: 55907.1 SUBSYSTEM: Fatty acid synthesis EC Number: 2.3.1.85 Confidence Level: 0 AUTHORS: PMID:7567999 NOTES:
type: Reaction
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/7567999
product: MODEL1109130000#

metaM L dpchrm c
name: L-dopachromate
is: HMDB01430
has only substance units: false
constant: false
boundary condition: false
is: CHEBI:57509
initial amount: NaN
initial concentration: 1.0
is: SBO:0000247
type: Species
notes: FORMULA: C9H6NO4 CHARGE: -1 INCHI: InChI=1S/C9H7NO4/c11-7-2-4-1-6(9(13)14)10-5(4)3-8(7)12/h2-3,6,10H,1H2,(H,13,14)/p-1/t6-/m0/s1 EHMN_ABBREVIATION: C01693

http://identifiers.org/biomodels.db/MODEL1109130000#_5f0d862c_a222_48d2_b770_7f396e928199
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2b405a7e_0554_4d29_aab9_cc300364ff77
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d955d461_2224_4b77_8a4b_e28458e008b2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_629fa22c_d935_4099_be5a_0d6a5533aabf
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_35436cf4_0f68_4880_9558_24636d6b05e0
value: 1000.0
type: LocalParameter

metaR r2112
modifier: MODEL1109130000#
type: Reaction
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
reactant: MODEL1109130000#
is: SBO:0000185
reversible: true
is described by: http://identifiers.org/pubmed/12739169
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_7708c81d_c9b7_43f2_99d7_8b6f4a468b8d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_98ff1d61_ed06_454e_9190_c24f0ab6c98a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b6a02ec3_a7ff_4027_a03a_aef1b9fc2e89
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0952ce73_648d_4771_a067_f77323107d77
units: dimensionless
value: 0.0
type: LocalParameter

metaM vacccoa m
is: SBO:0000247
is: HMDB06521
name: vaccenyl coenzyme A
has only substance units: false
notes: FORMULA: C39H64N7O17P3S CHARGE: -4 INCHI: InChI=1/C39H68N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(48)67-23-22-41-29(47)20-21-42-37(51)34(50)39(2,3)25-60-66(57,58)63-65(55,56)59-24-28-33(62-64(52,53)54)32(49)38(61-28)46-27-45-31-35(40)43-26-44-36(31)46/h9-10,26-28,32-34,38,49-50H,4-8,11-25H2,1-3H3,(H,41,47)(H,42,51)(H,55,56)(H,57,58)(H2,40,43,44)(H2,52,53,54)/b10-9+/t28-,32-,33?,34+,38-/m1/s1
type: Species
initial amount: NaN
constant: false
initial concentration: 1.0
is: http://identifiers.org/pubchem.substance/9543677
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_5779102c_19ad_4886_a251_4f5c27ab2979
value: 1000.0
type: LocalParameter

metaM gthrd c
is: SBO:0000247
constant: false
initial concentration: 1.0
notes: FORMULA: C10H16N3O6S CHARGE: -1 HEPATONET_1.0_ABBREVIATION: HC00056 EHMN_ABBREVIATION: C00051 INCHI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/p-1/t5-,6-/m0/s1
is: CHEBI:57925
type: Species
is: HMDB00125
initial amount: NaN
has only substance units: false
is: C00051
name: Reduced glutathione
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_7db2d15b_f90d_4253_ab4f_8c4aafa43614
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_36abeba8_21fd_4378_b54b_fba391bdef0e
units: dimensionless
value: 0.0
type: LocalParameter

metaR ACCOAL
is version of: http://identifiers.org/ec-code/6.2.1.13
is: SBO:0000176
name: acetate-CoA ligase (ADP-forming)
product: MODEL1109130000#
modifier: MODEL1109130000#
is version of: ECO:0000269
type: Reaction
fast: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (55902.1) or (55902.2) SUBSYSTEM: Propanoate metabolism EC Number: 6.2.1.13 Confidence Level: 4 AUTHORS: PMID:10843999 NOTES: JLR- also acts on propanoate
reversible: false
is described by: http://identifiers.org/pubmed/10843999

metaM CE2196 c
initial concentration: 1.0
name: (R)-1,2-dimethyl-5,6-dihydroxy-tetrahydroisoquinoline
boundary condition: false
initial amount: NaN
has only substance units: false
type: Species
constant: false
is: SBO:0000247
notes: FORMULA: C11H16NO2 CHARGE: 1 INCHI: EHMN_ABBREVIATION: CE2196

metaR LPCHOLt
is described by: http://identifiers.org/pubmed/9430701
is version of: ECO:0000000
reactant: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
reversible: true
name: lysophosphatidylcholine transport
is: SBO:0000185
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:9430701 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#e24b00e7_ff98_49aa_a4f5_6af570638e81
units: dimensionless
value: 0.0
type: LocalParameter

metaM octeACP c
boundary condition: false
initial concentration: 1.0
constant: false
notes: FORMULA: C29H53N2O8PRS CHARGE: -1 INCHI:
is: SBO:0000247
type: Species
name: cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_443f97cb_0f49_4449_a55f_1a9263a85fe6
initial concentration: NaN
boundary condition: true
name: GALK1
is encoded by: hsa:2584
has only substance units: false
is: SBO:0000252
type: Species
initial amount: NaN
constant: true
is: P51570

http://identifiers.org/biomodels.db/MODEL1109130000#_07369abe_b582_4894_b049_842ea48e983a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_87ee3599_d77f_489d_a470_11ede1a3232d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74e5a506_87c0_44ef_8964_3c275da8f9a8
initial concentration: NaN
type: Species
boundary condition: true
is encoded by: hsa:318
name: NUDT2
is: P50583
initial amount: NaN
has only substance units: false
is: SBO:0000252
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_9ec8ed4c_3348_4479_90e7_05b4c62eb516
value: 0.0
type: LocalParameter

metaM CN0017 x
notes: FORMULA: CHARGE: 0 EHMN_ABBREVIATION: CN0017 INCHI:
constant: false
name: Dibenzo[a,l]pyrene-11,12-epoxide
boundary condition: false
is: SBO:0000247
initial concentration: 1.0
has only substance units: false
initial amount: NaN
type: Species

metaR RE1537C
product: MODEL1109130000#
name: RE1537
type: Reaction
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.5.3.11
is described by: http://identifiers.org/pubmed/9359869
notes: GENE_ASSOCIATION: SUBSYSTEM: Urea cycle EC Number: 1.5.3.11 Confidence Level: 0 AUTHORS: PMID:11454677,PMID:9359869 NOTES:
reactant: MODEL1109130000#
fast: false
reversible: false
is described by: http://identifiers.org/pubmed/11454677

http://identifiers.org/biomodels.db/MODEL1109130000#a0bfd922_9ece_4be6_8937_624e2b66a5a3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ee36966c_96f2_4618_bf06_5dde5986fa4d
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5945 c
boundary condition: false
has only substance units: false
is: SBO:0000247
constant: false
initial amount: NaN
notes: FORMULA: C20H33O6 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5945
initial concentration: 1.0
type: Species
name: 10,11-dihydro-20-dihydroxy-LTB4

http://identifiers.org/biomodels.db/MODEL1109130000#edc0cc98_1897_462b_b7c7_115cf8cf839f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_95a331e4_00dc_4920_9f90_4b1f526b0a98
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1766d3dc_28c2_4862_afd7_059a0d6bf3d4
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V1C1:ATP6V1E1:ATP6V1G2:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#aec9d488_38fa_4529_83cf_8d6766109c5b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a75985dc_dc42_4707_bfd1_68e1cee54c33
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_78684d2f_7f02_460a_a061_685593dd43af
value: 0.0
type: LocalParameter

metaR RE3141X
name: RE3141
is version of: http://identifiers.org/ec-code/1.1.1.35
reactant: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: (3295.1) or (1962.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:11734209 NOTES:
product: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000176
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/11734209

http://identifiers.org/biomodels.db/MODEL1109130000#_9e2ac0a2_1da0_4991_9c44_a22eec6da4c0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f805c18d_9044_461e_929a_46cf22d66f16
units: dimensionless
value: 0.0
type: LocalParameter

metaR PFK26
product: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction
name: 6-phosphofructo-2-kinase
reversible: false
fast: false
is: SBO:0000176
reactant: MODEL1109130000#
is version of: ECO:0000000
notes: GENE_ASSOCIATION: (5210.1) or (5207.1) or (5209.1) or (5208.1) SUBSYSTEM: Fructose and mannose metabolism EC Number: 2.7.1.105 Confidence Level: 0 AUTHORS: NOTES: IF
is version of: http://identifiers.org/ec-code/2.7.1.105

metaM gthrd e
constant: false
name: glutathionate(1-)
initial concentration: 1.0
is: HMDB00125
initial amount: NaN
notes: FORMULA: C10H16N3O6S CHARGE: -1 INCHI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/p-1/t5-,6-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00056 EHMN_ABBREVIATION: C00051
is: CHEBI:57925
type: Species
is: SBO:0000247
has only substance units: false
boundary condition: false

metaM CE5588 c
has only substance units: false
initial amount: NaN
name: deoxyhypusine
boundary condition: false
is: CHEBI:50038
notes: FORMULA: C10H25N3O2 CHARGE: 2 INCHI: InChI=1S/C10H23N3O2/c11-6-2-4-8-13-7-3-1-5-9(12)10(14)15/h9,13H,1-8,11-12H2,(H,14,15)/t9-/m0/s1 EHMN_ABBREVIATION: CE5588
initial concentration: 1.0
constant: false
type: Species
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#f11f98cb_385f_445f_8ab2_c1632253c90e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_87588773_d1c1_4c92_a9fc_5d0310933deb
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4c7922f1_9451_4151_b7c3_3bf642b6ecbe
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b63d59c6_dbb2_4923_9091_42ce25f1f084
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9e65259d_e817_4add_9e02_18cfb0f18ee3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b202b661_99d7_41ad_b239_e3184c575883
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1ed2dd85_07da_4981_bbb7_ecbeac7c377f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_83c542aa_726c_4e20_944b_36f53d7efa98
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7da42a26_4816_41b3_bcf6_1ff83959aa25
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_34ae21b9_6bd9_49e0_b731_dca4d3dc437b
initial concentration: NaN
type: Species
initial amount: NaN
constant: true
is: SBO:0000252
is encoded by: hsa:5152
has only substance units: false
name: PDE9A
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_8ad6e86a_c1c2_4b8e_91e6_1a75d4608580
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1260ae61_e20e_40b0_bc07_cbed0e110090
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_770c1c37_5355_4942_98f3_b4ebd9ff530d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ee025edc_0451_46ef_a2bc_c079232b5c1f
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5244 r
is: SBO:0000247
name: 4-hydroxyestrone-2-S-glutathione
has only substance units: false
type: Species
initial amount: NaN
notes: FORMULA: C28H36N3O9S CHARGE: -1 INCHI: InChI=1/C28H37N3O9S/c1-28-9-8-13-14(17(28)4-6-21(28)32)2-3-15-16(13)10-20(25(37)24(15)36)41-12-19(26(38)30-11-23(34)35)31-22(33)7-5-18(29)27(39)40/h10,13-14,17-19,36-37H,2-9,11-12,29H2,1H3,(H,30,38)(H,31,33)(H,34,35)(H,39,40)/p-1/t13-,14+,17-,18+,19+,28+/m0/s1 EHMN_ABBREVIATION: CE5244
initial concentration: 1.0
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_94af5da0_b7e7_4f6e_81c3_b46b756263fb
value: 0.0
type: LocalParameter

metaR Htr
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 1 AUTHORS: NOTES: diffusion NJ
name: H transporter, endoplasmic reticulum
type: Reaction
is: SBO:0000185
fast: false
product: MODEL1109130000#
reversible: true
reactant: MODEL1109130000#

metaR RE2150R
is: SBO:0000176
name: RE2150
type: Reaction
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Vitamin A metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:8295481 NOTES:
fast: false
is described by: http://identifiers.org/pubmed/8295481
modifier: MODEL1109130000#
reversible: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.17

http://identifiers.org/biomodels.db/MODEL1109130000#_6c7eceaf_e145_46a1_8777_1e7aeff0d2e4
has only substance units: false
notes: DRUGBANK_UNKNOWN: DB00145, DB01752, DB04272 DRUGBANK_COFACTOR: DB00118
constant: false
boundary condition: true
is: Q14749
initial amount: NaN
is encoded by: hsa:27232
name: GNMT
initial concentration: NaN
is: SBO:0000252
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_19ba76f0_90ab_4c1c_9155_9242bd7f52ff
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_bd14bc71_5a96_46de_90c3_68b222cfed47
initial amount: NaN
boundary condition: true
type: Species
is encoded by: hsa:8525
has only substance units: false
is: J3KNJ6
constant: true
initial concentration: NaN
name: DGKZ
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_3ddd896d_5c4c_4acb_a32e_422acad26366
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaR RE3554C
is version of: http://identifiers.org/ec-code/2.5.1.18
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/9755286
is: SBO:0000176
type: Reaction
name: RE3554
reactant: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: 2.5.1.18 Confidence Level: 0 AUTHORS: PMID:9755286 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#a838baac_378b_4bea_934f_516d6205a727
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3869649d_999b_4a32_9ba3_199e094615b0
is: SBO:0000252
name: GALNT10
type: Species
initial concentration: NaN
initial amount: NaN
constant: true
has only substance units: false
is encoded by: hsa:55568
boundary condition: true

metaR MM7Cbg
reversible: false
is version of: ECO:0000000
notes: GENE_ASSOCIATION: (57134.1) or (10905.1) or (4121.1) SUBSYSTEM: N-glycan synthesis EC Number: 3.2.1.113 Confidence Level: 0 AUTHORS: PMID:10915796,PMID:9592125 NOTES: NCD
reactant: MODEL1109130000#
modifier: MODEL1109130000#
name: mannosyl-oligosaccharide 1,2-alpha-mannosidase, Golgi apparatus
type: Reaction
is: SBO:0000176
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9592125
is version of: http://identifiers.org/ec-code/3.2.1.113
fast: false
is described by: http://identifiers.org/pubmed/10915796

http://identifiers.org/biomodels.db/MODEL1109130000#_2c72ddc2_7b00_44df_86f7_9e2033c683f1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5da5c876_e41e_4eee_958e_ad3b716a002d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e04d8d97_4cbb_43fa_8207_e7de7d6ff1e5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_83dab0a1_90cf_4f95_9675_8c956d9c0502
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6d8daa4b_8877_4a4f_9e3a_3245099801ca
has only substance units: false
name: null
initial amount: NaN
is: SBO:0000252
boundary condition: true
is encoded by: hsa:AI601100
initial concentration: NaN
type: Species
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_55250baf_28c4_4dc6_b60e_3c16893e9345
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2067b0a5_ba2c_484e_830c_ef17ee3bfb29
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_270391b5_8cf9_4ba0_b43d_950e79b58632
initial amount: NaN
boundary condition: true
type: Species
is: SBO:0000252
initial concentration: NaN
is encoded by: hsa:1716
has only substance units: false
constant: true
name: DGUOK

http://identifiers.org/biomodels.db/MODEL1109130000#_6724ffb3_4c6a_4ae6_a0ea_09a3fa6ef93e
value: 0.0
type: LocalParameter

metaR ATPasel
is: SBO:0000185
modifier: MODEL1109130000#
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.6.3.14
reversible: false
is version of: ECO:0000269
notes: GENE_ASSOCIATION: (50617.1 and 533.1 and 527.1 and 8992.1 and 245972.1 or 50617.1 and 533.1 and 527.1 and 8992.1 and 9114.1 or 533.1 and 527.1 and 8992.1 and 535.1 and 245972.1 or 533.1 and 527.1 and 8992.1 and 535.1 and 9114.1 or 533.1 and 527.1 and 8992.1 and 50617.3 and 245972.1 or 533.1 and 527.1 and 8992.1 and 10312.1 and 9114.1 or 533.1 and 527.1 and 8992.1 and 245972.1 and 50617.2 or 533.1 and 527.1 and 8992.1 and 9114.1 and 23545.1 or 533.1 and 527.1 and 8992.1 and 10312.2 and 245972.1 or 533.1 and 527.1 and 8992.1 and 50617.3 and 9114.1 or 533.1 and 527.1 and 8992.1 and 245972.1 and 23545.1 or 533.1 and 527.1 and 8992.1 and 9114.1 and 50617.2 or 533.1 and 527.1 and 8992.1 and 10312.1 and 245972.1 or 533.1 and 527.1 and 8992.1 and 10312.2 and 9114.1) and (51382.1 and 9296.1 and 529.1 and 245973.1 and 523.1 and 51606.1 and 9550.1 and 526.1 or 51382.1 and 9296.1 and 127124.1 and 245973.1 and 525.1 and 90423.1 and 51606.2 and 523.1 or 51382.1 and 51606.3 and 9296.1 and 534.2 and 90423.1 and 523.1 and 526.1 and 528.2 or 51382.1 and 9296.1 and 245973.1 and 534.2 and 523.1 and 90423.1 and 51606.1 and 526.1 or 51382.1 and 9296.1 and 534.1 and 51606.2 and 529.1 and 528.1 and 523.1 and 526.1 or 51382.1 and 51606.3 and 9296.1 and 534.1 and 529.1 and 523.1 and 528.2 and 526.1 or 51382.1 and 51606.3 and 9296.1 and 127124.1 and 529.1 and 525.1 and 523.1 and 528.2 or 51382.1 and 9296.1 and 245973.1 and 90423.1 and 127124.2 and 51606.2 and 523.1 and 526.1 or 51382.1 and 9296.1 and 127124.1 and 529.1 and 525.1 and 523.1 and 51606.1 and 528.2 or 51382.1 and 9296.1 and 51606.2 and 529.1 and 245973.1 and 534.2 and 525.1 and 523.1 or 51382.1 and 9296.1 and 534.1 and 528.1 and 523.1 and 90423.1 and 51606.1 and 526.1 or 51382.1 and 51606.3 and 9296.1 and 523.1 and 90423.1 and 9550.1 and 528.2 and 526.1 or 51382.1 and 51606.3 and 9296.1 and 534.1 and 245973.1 and 525.1 and 90423.1 and 523.1 or 51382.1 and 9296.1 and 534.1 and 525.1 and 529.1 and 528.1 and 523.1 and 51606.1 or 5138…
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12628346
type: Reaction
is described by: http://identifiers.org/pubmed/10224039
name: V-type ATPase, H+ transporting, lysosomal
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#d7b02b2a_2602_4fa1_85c5_4367505e3017
value: 1000.0
type: LocalParameter

metaR ENMAN6g
is: SBO:0000176
reactant: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: N-glycan synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: NCD
reversible: false
is version of: ECO:0000000
product: MODEL1109130000#
type: Reaction
name: Endomannosidase (m5masnB1-producing), Golgi apparatus

http://identifiers.org/biomodels.db/MODEL1109130000#bfc7e382_0975_4863_9f9b_6743f2fe3686
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_557e768a_1676_4e55_ae26_c81b72208a98
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_20462609_d48f_47c0_b2ec_03caaaeb8a51
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5573aa23_e3a9_440f_8a6f_854602a123d2
boundary condition: true
type: Species
initial amount: NaN
has only substance units: false
constant: false
initial concentration: NaN
is: SBO:0000252
is encoded by: hsa:55229
name: PANK4
is: Q9NVE7

metaM gt2 hs g
constant: false
initial amount: NaN
type: Species
has only substance units: false
initial concentration: 1.0
notes: FORMULA: C71H117N5O41FULLRCO CHARGE: -3 INCHI:
name: GT2
is: SBO:0000247
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#c7fa91ee_854e_4cb4_8272_f71ef03c5274
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8607dffc_e1b0_4c49_a962_2e94ef0a54ef
value: 0.0
type: LocalParameter

metaM CE2303 r
boundary condition: false
is: SBO:0000247
constant: false
initial concentration: 1.0
name: 9-hydroxy-10-O-D-glucuronoside-12Z-octadecenoate
type: Species
initial amount: NaN
has only substance units: false
notes: FORMULA: C24H40O10 CHARGE: -2 INCHI: InChI=1/C24H42O10/c1-2-3-4-5-8-11-14-17(16(25)13-10-7-6-9-12-15-18(26)27)33-24-21(30)19(28)20(29)22(34-24)23(31)32/h8,11,16-17,19-22,24-25,28-30H,2-7,9-10,12-15H2,1H3,(H,26,27)(H,31,32)/p-2/b11-8-/t16u,17u,19-,20+,21-,22-,24?/m0/s1 EHMN_ABBREVIATION: CE2303

http://identifiers.org/biomodels.db/MODEL1109130000#_5ed4cd67_2709_4433_a3f7_8edd7cc94c26
value: -1000.0
type: LocalParameter

metaM CE7112 c
boundary condition: false
constant: false
notes: FORMULA: C20H29O5 CHARGE: -1 EHMN_ABBREVIATION: CE7112 INCHI: InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h3-4,6-7,12-13,15-17,19,21,23H,2,5,8-11,14H2,1H3,(H,24,25)/b6-3-,7-4-,13-12+/t15-,16+,17+,19+/m0/s1
type: Species
name: 15-epi-lipoxin A5
initial concentration: 1.0
has only substance units: false
initial amount: NaN
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_82d6b978_d499_497a_82fe_5d59bf108f05
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a1d8da2c_1b11_4647_817b_5d0d7e0fbdf0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c64809f9_c0a3_401b_b0be_c5dab5870e69
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_92630556_35e7_4b7f_aef9_d4b684db7277
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9eaf172d_0b9e_44b2_8f4f_7919c01b61db
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_86691fb3_1f5a_4127_a1f9_118670c8e57c
value: 0.0
type: LocalParameter

metaM vacccoa c
boundary condition: false
is: SBO:0000247
initial concentration: 1.0
constant: false
notes: FORMULA: C39H64N7O17P3S CHARGE: -4 INCHI: InChI=1/C39H68N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(48)67-23-22-41-29(47)20-21-42-37(51)34(50)39(2,3)25-60-66(57,58)63-65(55,56)59-24-28-33(62-64(52,53)54)32(49)38(61-28)46-27-45-31-35(40)43-26-44-36(31)46/h9-10,26-28,32-34,38,49-50H,4-8,11-25H2,1-3H3,(H,41,47)(H,42,51)(H,55,56)(H,57,58)(H2,40,43,44)(H2,52,53,54)/b10-9+/t28-,32-,33?,34+,38-/m1/s1
has only substance units: false
is: HMDB06521
initial amount: NaN
is: http://identifiers.org/pubchem.substance/9543677
name: vaccenyl coenzyme A
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_83643ae8_bb06_48b9_81bd_6953707434e5
value: 0.0
type: LocalParameter

metaR r1380
is described by: http://identifiers.org/pubmed/9638657
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: true
name: delta24-sterol reductase Biosynthesis of steroids EC:1.3.1.72
is: SBO:0000176
is described by: http://identifiers.org/pubmed/9291139
notes: GENE_ASSOCIATION: SUBSYSTEM: Cholesterol metabolism EC Number: 1.3.1.72 Confidence Level: 0 AUTHORS: PMID:12162789,PMID:9291139,PMID:9638657 NOTES:
fast: false
is version of: http://identifiers.org/ec-code/1.3.1.72
type: Reaction
is described by: http://identifiers.org/pubmed/12162789

http://identifiers.org/biomodels.db/MODEL1109130000#_10c75b25_f14f_48de_8de6_0f132e50237f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a3cda8a1_d142_479c_8bfb_e62cf8062ff8
value: 0.0
type: LocalParameter

metaR RE3184M
is described by: http://identifiers.org/pubmed/9819701
name: RE3184
modifier: MODEL1109130000#
is: SBO:0000176
notes: GENE_ASSOCIATION: (34.1) or (33.1) or (36.1) SUBSYSTEM: Fatty acid oxidation EC Number: 1.3.99.3 Confidence Level: 0 AUTHORS: PMID:10407780,PMID:9469587,PMID:9819701 NOTES:
type: Reaction
reversible: true
product: MODEL1109130000#
fast: false
is version of: http://identifiers.org/ec-code/1.3.99.3
is described by: http://identifiers.org/pubmed/9469587
is described by: http://identifiers.org/pubmed/10407780
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_647fd0ec_a2ca_4443_95ed_d718224e95a7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b9760e9_fd84_423a_ba60_aebe1695a946
constant: true
is: P22352
is: SBO:0000252
is encoded by: hsa:2878
initial amount: NaN
boundary condition: true
name: GPX3
type: Species
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#e5e92558_53fb_4b18_8ab6_7ca77d3f3ab8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a345ea12_1368_4658_b901_8b155c3a1a1e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_28f14c97_64cd_4edd_b5f7_44a9244b0566
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b6124624_f088_43dd_b199_e78c3fb2f53f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_13af5e3e_3879_4f3c_afcb_64ca8f5b6f7a
units: dimensionless
value: 0.0
type: LocalParameter

metaR DHCR241r
is version of: ECO:0000134
name: 24-dehydrocholesterol reductase [Precursor]
reversible: false
type: Reaction
is described by: http://identifiers.org/pubmed/19520779
fast: false
product: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/19520780
notes: GENE_ASSOCIATION: 1718.1 SUBSYSTEM: Cholesterol metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:17984220,PMID:19520779,PMID:19520780 NOTES: lanosterol -> cholesterol pathway FAD known to be cofactor, other details missing NJ
is: SBO:0000176
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/17984220

http://identifiers.org/biomodels.db/MODEL1109130000#_19ec263d_de02_47ea_bc9b_d0ad15a39f3f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7d79f184_8f7a_45c9_85a4_14f84b930483
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ba7d9bfd_4797_48ab_aba7_ad4303658f20
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1381
name: 5alpha-Cholest-7-en-3beta-ol delta7-delta8-isomerase Biosynthesis of steroids EC:5.3.3.5
fast: false
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/5.3.3.5
is: SBO:0000176
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/4475632
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Cholesterol metabolism EC Number: 5.3.3.5 Confidence Level: 0 AUTHORS: PMID:12133002,PMID:4475632,PMID:5810070 NOTES:
is described by: http://identifiers.org/pubmed/5810070
type: Reaction
is described by: http://identifiers.org/pubmed/12133002

metaR BALAtmr
name: Beta-alanine reversible mitochondrial transport (diffusion)
fast: false
is: SBO:0000185
is described by: http://identifiers.org/pubmed/15304357
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 1 AUTHORS: PMID:15304357 NOTES: SAB
is version of: ECO:0000000
reversible: true
reactant: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_8075b13b_d331_4109_b3ad_8a603fe2f14e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dae4b5ea_294f_45f6_803a_4ee537d44e48
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3e64880d_c088_41f1_8647_80abefa48b0b
value: 0.0
type: LocalParameter

metaM CN0017 r
constant: false
name: Dibenzo[a,l]pyrene-11,12-epoxide
has only substance units: false
type: Species
boundary condition: false
is: SBO:0000247
notes: FORMULA: CHARGE: 0 EHMN_ABBREVIATION: CN0017 INCHI:
initial concentration: 1.0
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#f0a457ed_6064_454d_95e1_4f6dfc1a75db
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ac883b62_470a_44b1_9d0a_74b0b753c3cd
value: 0.0
type: LocalParameter

metaR RNMK
reversible: false
name: ribosylnicotinamide kinase
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.1.22
is version of: ECO:0000269
is: SBO:0000176
fast: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 54981.1 SUBSYSTEM: NAD metabolism EC Number: 2.7.1.22 Confidence Level: 4 AUTHORS: PMID:15137942 NOTES:
is described by: http://identifiers.org/pubmed/15137942
modifier: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_86a9a80f_94e9_4f69_8c11_2716d5b1fe7e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4a0c965b_9936_4796_929e_c9a64d6637b2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_93f985fd_a5a1_4fb4_b9a2_9eecc1b3d10e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_65adb671_84c1_47bf_b12e_60d8a6eea15d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5be4c117_b816_43e0_bb2f_15a5e8c117b1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#af299870_6529_4820_9e98_e3d7cfe59591
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9a5b330c_6359_4427_bd4c_89d72a4f7976
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d9379ece_5d51_4be4_b075_474f80647122
units: dimensionless
value: 0.0
type: LocalParameter

metaR OCDCEAtr
reversible: true
product: MODEL1109130000#
type: Reaction
is: SBO:0000185
is described by: http://identifiers.org/pubmed/11788354
name: fatty acid transport via diffusion
fast: false
is described by: http://identifiers.org/pubmed/12864740
is version of: ECO:0000000
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:11788354,PMID:12864740 NOTES: NJ

metaR TETPENT6CRNt
modifier: MODEL1109130000#
type: Reaction
is version of: ECO:0000269
is: SBO:0000185
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 788.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: NOTES: NJ
fast: false
name: transport into the mitochondria (carnitine)
reversible: false
product: MODEL1109130000#

metaM L dpchrm x
name: L-dopachromate
is: CHEBI:57509
has only substance units: false
boundary condition: false
constant: false
notes: FORMULA: C9H6NO4 CHARGE: -1 INCHI: InChI=1S/C9H7NO4/c11-7-2-4-1-6(9(13)14)10-5(4)3-8(7)12/h2-3,6,10H,1H2,(H,13,14)/p-1/t6-/m0/s1 EHMN_ABBREVIATION: C01693
is: HMDB01430
initial concentration: 1.0
initial amount: NaN
type: Species
is: SBO:0000247

metaM HC01651 c
is: C05922
is: SBO:0000247
has only substance units: false
boundary condition: false
constant: false
initial concentration: 1.0
type: Species
notes: FORMULA: CHARGE: 0 EHMN_ABBREVIATION: C05922
initial amount: NaN
is: http://identifiers.org/pubchem.substance/8210
name: Formamidopyrimidine nucleoside triphosphate

http://identifiers.org/biomodels.db/MODEL1109130000#c662aa34_5ecf_415f_9737_fd8f33482fe3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bd643ce0_1b29_426f_9ca1_6b2b36597cee
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ffcd7735_ec67_4205_904e_b3e06efdf90d
initial concentration: NaN
initial amount: NaN
boundary condition: true
is: SBO:0000252
is: Q7L266
type: Species
name: ASRGL1
constant: false
has only substance units: false
is encoded by: hsa:80150

http://identifiers.org/biomodels.db/MODEL1109130000#a7dac6de_e2e5_4443_88eb_0a69c4ff4dc8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8f5d6cce_2b7a_4ab7_b0a0_90e16001f647
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f9d8932c_c4e1_4239_aa58_5d74ea7beef0
value: 0.0
type: LocalParameter

metaR PALFATPtc
is described by: http://identifiers.org/pubmed/10518211
is: SBO:0000185
type: Reaction
reactant: MODEL1109130000#
name: uptake of Hexadecanoate by the enterocytes
is described by: http://identifiers.org/pubmed/20086080
product: MODEL1109130000#
modifier: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/2009
is described by: http://identifiers.org/pubmed/12856180
fast: false
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 10518211, PMID: 20086080, PMID: 12856180, Immun., Endoc. & Metab. Agents in Med. Chem., 2009, 9, 11-17, EC Number: NOTES: major intestinal fatty acid transport protein, may also act in co-ordination with acyl co-A synthetase. The transport is ATP driven, further the transporter itself has fatty acid activating enzymic properties (PMID: 12856180). GENE_ASSOCIATION: 10999.1
is described by: http://identifiers.org/pubmed/9

http://identifiers.org/biomodels.db/MODEL1109130000#_3d64d384_1a08_4931_be67_599fbd8e8c60
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_11f806e1_0256_4082_9d35_cb6e0982fc25
is encoded by: hsa:6240
has only substance units: false
has part: P23921
initial concentration: NaN
name: RRM1:RRM2
is: SBO:0000297
constant: false
is encoded by: hsa:6241
type: Species
has part: P31350
boundary condition: true
initial amount: NaN

metaR RN0002R
reversible: false
is: SBO:0000176
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Selenoamino acid metabolism EC Number: 2.1.1.13 Confidence Level: 0 AUTHORS: NOTES: IT - fixed proton
product: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction
is version of: http://identifiers.org/ec-code/2.1.1.13
name: RN0002

http://identifiers.org/biomodels.db/MODEL1109130000#_4a2a5fbb_60e5_4682_a3e6_ca8c7de44a90
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0ba2ee70_388f_4524_8988_5c32a01e3806
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cda17947_394b_40bb_a89a_08a16ac52aec
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6214792e_7b45_42ad_9718_a58a446d3e19
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_347ecede_c267_42a2_b6c1_f1bcbe10c687
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#de99108d_0f5a_42c8_965a_cf75ec0e3aba
value: 0.0
type: LocalParameter

metaR FOAXC122C101x
is described by: http://identifiers.org/pubmed/20558530
name: fatty acid beta oxidation(C12:2-->C10:1)x
is: SBO:0000176
modifier: MODEL1109130000#
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
reversible: false
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID:20558530 EC Number: NOTES: peroxisomal beta oxidation GENE_ASSOCIATION: (1962.1 and 3295.1 and 30.1)
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_831dae17_c18f_4952_bc03_ac6f12cb0909
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dd1bd818_8921_4630_98e5_f6b7349ad14d
value: 0.0
type: LocalParameter

metaM docosac c
has only substance units: false
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C22H43O2 CHARGE: -1
name: Behenic acid
type: Species
constant: false
initial amount: NaN
is: C08281
is: HMDB00944
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_52b31ee8_c746_42fb_a6e7_3ef94f0becd5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1e4d4d69_3640_4c79_9722_561b44b9cc68
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b8c4c78f_e7eb_42dd_8fa4_5689c587bdc0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33a3feb0_af14_46fe_ad14_b2befb49ab2b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ad70f5bf_81a1_46c0_aae4_ef432c19d212
units: dimensionless
value: 0.0
type: LocalParameter

metaR H7 TAer
is described by: http://identifiers.org/pubmed/10727241
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15632136
fast: false
is: SBO:0000176
name: H7 transamidase, endoplasmic reticulum
is described by: http://identifiers.org/pubmed/9468317
is described by: http://identifiers.org/pubmed/9356492
notes: GENE_ASSOCIATION: SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:10727241,PMID:11483512,PMID:12802054,PMID:15632136,PMID:9356492,PMID:9468317 NOTES: EC 2.6.-.- NCD
is described by: http://identifiers.org/pubmed/12802054
reversible: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11483512
is version of: ECO:0000000
type: Reaction

metaM cs d pre5 g
has only substance units: false
boundary condition: false
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 5
notes: FORMULA: C45H65N2O48S4X CHARGE: -6 INCHI:
initial amount: NaN
is: SBO:0000247
constant: false
type: Species
initial concentration: 1.0

metaR VALt4
is described by: http://identifiers.org/pubmed/11133652
type: Reaction
reversible: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 11254.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:11133652,PMID:12719981 NOTES: SAB
is version of: ECO:0000304
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/12719981
name: L-valine transport in via sodium symport
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_5db4119e_bbb4_4c89_9d00_67a9f9a6e710
value: 1000.0
type: LocalParameter

metaR r1386
is version of: http://identifiers.org/ec-code/3.5.4.15
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10348987
notes: GENE_ASSOCIATION: SUBSYSTEM: Lysine metabolism EC Number: 3.5.4.15 Confidence Level: 0 AUTHORS: PMID:10348987,PMID:14725335 NOTES:
reversible: false
fast: false
name: Virtual reaction/potential definition
is described by: http://identifiers.org/pubmed/14725335
product: MODEL1109130000#
type: Reaction
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_58e40c82_9f20_4cdb_8795_1671bccbc357
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_65cad28b_82c0_40f4_96e8_aae894bf92cb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cb9c9a12_4d88_49ac_b4e4_591b39401a54
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1382
is described by: http://identifiers.org/pubmed/7142207
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/6.3.2.17
is described by: http://identifiers.org/pubmed/2645826
is: SBO:0000176
fast: false
reversible: false
name: folylpolyglutamyl synthetase EC:6.3.2.17
is described by: http://identifiers.org/pubmed/16859665
is described by: http://identifiers.org/pubmed/7027025
is described by: http://identifiers.org/pubmed/2695555
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Folate metabolism EC Number: 6.3.2.17 Confidence Level: 0 AUTHORS: PMID:16859665,PMID:2645826,PMID:2695555,PMID:7027025,PMID:7142207 NOTES:
reactant: MODEL1109130000#

metaM docosac e
type: Species
is: SBO:0000247
is: C08281
notes: FORMULA: C22H43O2 CHARGE: -1
is: HMDB00944
has only substance units: false
initial concentration: 1.0
boundary condition: false
name: Behenic acid
initial amount: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#f3d8fb72_57e1_4e5a_91b4_1befd88ea3b9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8afd7c89_926b_4770_8aaf_d95895fbc25a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d7589f7c_273c_4eb7_850d_5f6079f743ad
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6743bcb0_a378_4449_8184_49bf21a4e1a1
value: -1000.0
type: LocalParameter

metaR DSAT
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: Sphingolipid metabolism EC Number: Confidence Level: 2 AUTHORS: NOTES: CoA transfer not explicitly in rxn (accounted for in Rtotal rxn -> ARTF) NJ
fast: false
product: MODEL1109130000#
type: Reaction
is: SBO:0000176
reactant: MODEL1109130000#
name: dihydrosphingosine N-acyltransferase
reversible: false

metaR r1383
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/16859665
is: SBO:0000176
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.4.19.9
name: gamma-glutamyl hydrolase EC:3.4.19.9
reversible: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Folate metabolism EC Number: 3.4.19.9 Confidence Level: 0 AUTHORS: PMID:12909365,PMID:16859665 NOTES:
is described by: http://identifiers.org/pubmed/12909365

http://identifiers.org/biomodels.db/MODEL1109130000#_75a46250_586b_40fb_9eba_07cb648a5d3c
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#d00dd073_7607_4a5f_a136_f58101e39990
value: 1000.0
type: LocalParameter

metaR ALAASNNaEx
type: Reaction
fast: false
is version of: ECO:0000269
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 6510.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:14530974 NOTES: SAB see Kanai and Hediger 2004 (2003), PMID 14530974
reversible: false
is: SBO:0000185
is described by: http://identifiers.org/pubmed/14530974
product: MODEL1109130000#
modifier: MODEL1109130000#
name: L-alanine/L-asparagine Na-dependent exchange (Ala-L in)

metaR THD1m
name: NAD(P) transhydrogenase
type: Reaction
is described by: http://identifiers.org/pubmed/8647343
is version of: ECO:0000269
is version of: http://identifiers.org/ec-code/1.6.1.2
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9524818
is described by: http://identifiers.org/pubmed/12223207
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (23530.2) or (23530.1) SUBSYSTEM: NAD metabolism EC Number: 1.6.1.2 Confidence Level: 4 AUTHORS: PMID:12223207,PMID:8647343,PMID:9524818 NOTES: TDV (2-6-2003)
reversible: true
is: SBO:0000185
fast: false
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_1762a5a1_19d4_4a80_8bf3_83aafc0e3878
is encoded by: hsa:2629
is: SBO:0000252
is: B7Z5G2
initial concentration: NaN
initial amount: NaN
boundary condition: true
constant: false
name: GBA
type: Species
has only substance units: false

metaR RE3106C
reversible: true
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/10970790
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
type: Reaction
is: SBO:0000176
name: RE3106

http://identifiers.org/biomodels.db/MODEL1109130000#ec801b34_0342_46bb_aed6_fb4db9cbd557
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f16936fe_c028_43a7_8c27_c5dd26bc40a4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9cd3e085_fbf4_41e5_82f2_87aecc887f6e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0c81ca5e_31a2_4e1d_b966_ed4afbd95e9a
name: RDH11
has only substance units: false
type: Species
is encoded by: hsa:51109
initial amount: NaN
is: SBO:0000252
boundary condition: true
initial concentration: NaN
is: B4DDW0
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#b60cdf5a_84b5_4b29_8410_bfa124f01c1b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2d7e470c_723f_4646_adcc_06b230b2898d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7b3b8a51_991c_4aff_94b4_4829afef69fe
type: Species
is: Q92935
constant: false
initial concentration: NaN
initial amount: NaN
has only substance units: false
is: SBO:0000252
name: EXTL1
is encoded by: hsa:2134
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#ed3c35f8_45c9_4069_a94c_6429bf796bec
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_63e8ee2f_0220_4cda_9a49_5a3bf9a6cfa5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_83e2f7b9_00e8_4931_85d7_25e6ee20ac97
units: dimensionless
value: 0.0
type: LocalParameter

metaR RN0002N
type: Reaction
is version of: http://identifiers.org/ec-code/2.1.1.13
notes: GENE_ASSOCIATION: SUBSYSTEM: Selenoamino acid metabolism EC Number: 2.1.1.13 Confidence Level: 0 AUTHORS: NOTES: IT - fixed proton
name: RN0002
is: SBO:0000176
reversible: false
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_175a2760_3ab9_4757_bb18_8e60cf0ac730
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18df247c_eb02_48fa_a6b2_327f0aad1df9
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1384
reversible: true
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Nucleotide interconversion EC Number: 3.5.4.15 Confidence Level: 0 AUTHORS: PMID:10348987,PMID:14725335 NOTES:
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/10348987
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14725335
name: Guanosine aminohydrolase EC:3.5.4.15
type: Reaction
is version of: http://identifiers.org/ec-code/3.5.4.15

http://identifiers.org/biomodels.db/MODEL1109130000#_2561c196_6f47_4cea_be0a_cb9ff7ec5282
initial amount: NaN
is: Q14123
is: SBO:0000252
has only substance units: false
is encoded by: hsa:5137
boundary condition: true
initial concentration: NaN
constant: true
name: PDE1C
type: Species

metaR Htg
reactant: MODEL1109130000#
reversible: true
type: Reaction
product: MODEL1109130000#
is: SBO:0000185
name: proton diffusion (Golgi)
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, golgi apparatus EC Number: Confidence Level: 2 AUTHORS: NOTES:
is version of: ECO:0000000
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#bc3d4675_04aa_4945_98fe_0e9906d32431
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e9afa871_84a1_4572_bb1e_ce68ffe99ac3
value: -1000.0
type: LocalParameter

metaR G14T11g
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.38
reactant: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/9435216
fast: false
name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi
is version of: ECO:0000000
type: Reaction
is described by: http://identifiers.org/pubmed/3144273
is described by: http://identifiers.org/pubmed/1903938
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9405390
notes: GENE_ASSOCIATION: (8703.1) or (8704.2) or (8704.1) or (2683.1) or (9334.1) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.1.38 Confidence Level: 4 AUTHORS: PMID:12512857,PMID:1903938,PMID:3094506,PMID:3144273,PMID:9405390,PMID:9435216 NOTES: Keratan sulfate I biosynthesis NCD
is described by: http://identifiers.org/pubmed/3094506
is: SBO:0000176
is described by: http://identifiers.org/pubmed/12512857

metaR r2114
reversible: true
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
type: Reaction
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#ab2fb370_19f2_4c26_9fce_d362317f336b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#adb24b9b_91ba_4527_aa8c_9f81e1a4cf7c
value: 0.0
type: LocalParameter

metaM hs pre1 g
initial concentration: 1.0
has only substance units: false
is: SBO:0000247
constant: false
notes: FORMULA: C31H49NO25X CHARGE: -1 INCHI:
type: Species
name: heparan sulfate, precursor 1
initial amount: NaN
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_424a8581_f6e3_49be_bd05_273863470db8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0b975247_287a_46d4_b362_33d859337ce7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8a6c13e2_92fc_4a00_b227_00eb13efb2c0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2b88b929_a6f3_4b20_9949_7409d0622dda
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b8c26055_2cc9_45bb_bf27_8f41d32fb926
name: ALOX15B
type: Species
is: O15296
initial amount: NaN
has only substance units: false
initial concentration: NaN
is: SBO:0000252
boundary condition: true
is encoded by: hsa:247
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_a8f2c269_4c16_4d87_930f_215975dd6c2e
initial concentration: NaN
is: Q9H9B1
is: SBO:0000252
has only substance units: false
initial amount: NaN
boundary condition: true
is encoded by: hsa:79813
type: Species
name: EHMT1
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_64f67fe3_a36c_46a2_a94b_d6b63307d697
value: 0.0
type: LocalParameter

metaR r2113
is described by: http://identifiers.org/pubmed/12739169
product: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
reversible: true
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is: SBO:0000185
reactant: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_b520dd3c_b7e0_4d2f_a22a_6b4018fe502e
is: SBO:0000252
constant: false
initial amount: NaN
is: Q9Y2A9
name: B3GNT3
boundary condition: true
initial concentration: NaN
is encoded by: hsa:10331
has only substance units: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_544c83c5_a0cf_4ae4_89dc_22b3ded36d1b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a77c6fc0_5ec7_411a_8953_498eb5799d97
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9773b805_dd2c_4f8a_a231_342539d3d1bd
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c305a976_c515_47ce_ab02_0797901d33a9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5017db62_1105_4481_a379_4df97cbc2495
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a83663dd_6b14_41f0_afc7_fa1e2cf04bb2
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c60db0b6_b256_4a34_9a05_9cd7d04af768
value: 0.0
type: LocalParameter

metaR r2116
is described by: http://identifiers.org/pubmed/12739169
reactant: MODEL1109130000#
reversible: true
fast: false
type: Reaction
modifier: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is: SBO:0000185
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_382040a7_837e_4c3c_aff2_129e4567bed3
units: dimensionless
value: 0.0
type: LocalParameter

metaR SRTNtu
is version of: ECO:0000269
reversible: true
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000185
name: Serotonin uniport
is described by: http://identifiers.org/pubmed/12883891
product: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: (6580.1) or (6582.2) or (6582.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:12883891 NOTES: SAB electrogenic, Na indepdendent & rev NJ
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_16be52d7_6b22_40f0_b2f9_92ef5ed1a2a5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_020db0b5_a74a_47f0_a2da_4c2065c73008
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#da6b284f_b583_46f6_8e98_7870f94dce5b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_cd0c98fa_9d55_44ab_bfb6_ddae76ec5def
constant: true
is encoded by: hsa:5052
initial amount: NaN
has only substance units: false
is: SBO:0000252
initial concentration: NaN
is: Q06830
name: PRDX1
boundary condition: true
type: Species

metaM CE7112 x
initial concentration: 1.0
notes: FORMULA: C20H29O5 CHARGE: -1 EHMN_ABBREVIATION: CE7112 INCHI: InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h3-4,6-7,12-13,15-17,19,21,23H,2,5,8-11,14H2,1H3,(H,24,25)/b6-3-,7-4-,13-12+/t15-,16+,17+,19+/m0/s1
name: 15-epi-lipoxin A5
type: Species
constant: false
initial amount: NaN
has only substance units: false
is: SBO:0000247
boundary condition: false

metaR RE3554R
type: Reaction
modifier: MODEL1109130000#
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.5.1.18
name: RE3554
fast: false
reversible: true
is described by: http://identifiers.org/pubmed/9755286
notes: GENE_ASSOCIATION: (4259.1) or (4258.1) or (4257.1) SUBSYSTEM: Eicosanoid metabolism EC Number: 2.5.1.18 Confidence Level: 0 AUTHORS: PMID:9755286 NOTES:
reactant: MODEL1109130000#
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_9bb30d73_6d41_4ae8_a0d2_703c6f1a0ce6
value: 0.0
type: LocalParameter

metaM orn e
name: Ornithine
initial concentration: 1.0
is: SBO:0000247
type: Species
initial amount: NaN
notes: FORMULA: C5H13N2O2 CHARGE: 1 INCHI:
is: HMDB00214
has only substance units: false
boundary condition: false
constant: false
is: C01602

http://identifiers.org/biomodels.db/MODEL1109130000#_66670773_a33d_4835_9d22_8536b5d8989b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_51fa60a5_5263_4aab_a586_d8113c499ec8
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9bff31d8_e82a_4643_b9f8_cd365671a272
constant: false
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:47
has only substance units: false
boundary condition: true
type: Species
name: ACLY
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_9157e09b_4a25_46f1_8d12_7cbe6a1cc436
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b58faf65_d943_466f_9d40_eda8df32d54b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bfa8f098_aa58_49f4_971d_ad0811f9a272
value: 0.0
type: LocalParameter

metaR r2115
fast: false
product: MODEL1109130000#
modifier: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is: SBO:0000185
reactant: MODEL1109130000#
reversible: true
type: Reaction
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is described by: http://identifiers.org/pubmed/12739169

metaM CE6226 x
initial concentration: 1.0
notes: FORMULA: C42H62N8O23P3S2 CHARGE: -5 INCHI: InChI=1/C42H67N8O23P3S2/c1-42(2,22-70-76(67,68)73-75(65,66)69-20-28-35(72-74(62,63)64)34(57)40(71-28)50-24-49-33-37(44)47-23-48-38(33)50)36(58)39(59)46-16-15-30(53)45-17-18-77-32(56)19-25(51)11-8-6-4-3-5-7-9-13-29(78-21-26(43)41(60)61)27(52)12-10-14-31(54)55/h3-5,7,9,13,23-29,34-36,40,51-52,57-58H,6,8,10-12,14-22,43H2,1-2H3,(H,45,53)(H,46,59)(H,54,55)(H,60,61)(H,65,66)(H,67,68)(H2,44,47,48)(H2,62,63,64)/p-5/b4-3-,7-5+,13-9+/t25-,26+,27-,28-,29+,34+,35+,36u,40-/m0/s1 EHMN_ABBREVIATION: CE6226
initial amount: NaN
is: SBO:0000247
has only substance units: false
name: 16(S)-hydroxy-18-oxo-18-CoA-LTE4
boundary condition: false
type: Species
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_1804b7e5_7a11_4186_b9c0_84da58e9aee0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_315d7c6c_2515_4c70_ba97_96981a5bd97f
value: 0.0
type: LocalParameter

metaR PGPPT
modifier: MODEL1109130000#
product: MODEL1109130000#
is: SBO:0000176
fast: false
notes: GENE_ASSOCIATION: 9489.1 SUBSYSTEM: Glycerophospholipid metabolism EC Number: 2.7.8.11 Confidence Level: 2 AUTHORS: PMID:10799718 NOTES: NJ
reversible: false
type: Reaction
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.7.8.11
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/10799718
name: phosphatidyl-CMP: glycerophosphate phosphatidyltransferase

http://identifiers.org/biomodels.db/MODEL1109130000#ff3a5f1f_4db9_48c6_ad05_9a4ec5926ae0
units: dimensionless
value: 0.0
type: LocalParameter

metaR HS1ly
is described by: http://identifiers.org/pubmed/9405287
is described by: http://identifiers.org/pubmed/8993162
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.10.1.1
is version of: ECO:0000000
type: Reaction
reactant: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/7493035
modifier: MODEL1109130000#
name: heparan-N-sulfatase, lysosomal
fast: false
notes: GENE_ASSOCIATION: 6448.1 SUBSYSTEM: Heparan sulfate degradation EC Number: 3.10.1.1 Confidence Level: 4 AUTHORS: PMID:7493035,PMID:8993162,PMID:9405287 NOTES: NCD
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#d7738458_ccb3_44cc_8626_809d9860ee99
value: 0.0
type: LocalParameter

metaM Rtotal2 c
notes: FORMULA: CO2FULLR2 CHARGE: -1 INCHI:
name: R total 2 position
is: SBO:0000247
type: Species
boundary condition: false
initial amount: NaN
initial concentration: 1.0
has only substance units: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_74c7783a_e215_45d1_a886_b13579a8d032
value: 1000.0
type: LocalParameter

metaR RE2405R
is version of: http://identifiers.org/ec-code/2.4.1.17
reversible: false
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Miscellaneous EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:10191290 NOTES:
is: SBO:0000176
reactant: MODEL1109130000#
fast: false
name: RE2405
product: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10191290
type: Reaction

metaM pyr c
initial amount: NaN
is: CHEBI:15361
is: HMDB00243
constant: false
type: Species
notes: FORMULA: C3H3O3 CHARGE: -1 INCHI: InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/p-1
has only substance units: false
is: http://identifiers.org/pubchem.substance/3324
name: pyruvate
initial concentration: 1.0
is: SBO:0000247
boundary condition: false
is: C00022

http://identifiers.org/biomodels.db/MODEL1109130000#_612fe3bd_9b9f_4634_ba28_a34eb186e0d5
units: dimensionless
value: 0.0
type: LocalParameter

metaR r2118
product: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is: SBO:0000185
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#b6e6a0d9_f469_444b_8e94_2e9296077a42
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8237a18a_db0f_49af_a4ac_1693bde5e068
value: 0.0
type: LocalParameter

metaM orn c
has only substance units: false
is: HMDB00214
is: C01602
type: Species
constant: false
name: Ornithine
notes: FORMULA: C5H13N2O2 CHARGE: 1 INCHI:
initial concentration: 1.0
initial amount: NaN
is: SBO:0000247
boundary condition: false

metaR EX itp LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Exchange of ITP(3-)
type: Reaction

metaM CE2206 m
has only substance units: false
notes: FORMULA: C27H42O4 CHARGE: 0 INCHI: InChI=1S/C27H42O4/c1-17(8-13-25(30)26(3,4)31)22-11-12-23-19(7-6-14-27(22,23)5)9-10-20-15-21(28)16-24(29)18(20)2/h9-10,17,21-24,28-29,31H,2,6-8,11-16H2,1,3-5H3/b19-9+,20-10-/t17-,21-,22-,23+,24+,27-/m1/s1 EHMN_ABBREVIATION: CE2206
initial concentration: 1.0
constant: false
name: 24-oxo-1alpha,25-dihydroxyvitamin D3
boundary condition: false
is: CHEBI:47812
is: SBO:0000247
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_56b24e33_28ee_4951_89b3_fad25ba89196
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8fb37f8e_3778_4a5d_a5fb_5574353012c0
has only substance units: false
boundary condition: true
is encoded by: hsa:92745
type: Species
initial concentration: NaN
is: SBO:0000252
initial amount: NaN
name: SLC38A5
constant: true
is: Q8WUX1

http://identifiers.org/biomodels.db/MODEL1109130000#e39f9cfb_569a_4c83_ab50_ea2e469af7e3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f55fd105_1c70_4e43_96ab_681d912d51e0
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE7112 r
is: SBO:0000247
boundary condition: false
initial concentration: 1.0
notes: FORMULA: C20H29O5 CHARGE: -1 EHMN_ABBREVIATION: CE7112 INCHI: InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h3-4,6-7,12-13,15-17,19,21,23H,2,5,8-11,14H2,1H3,(H,24,25)/b6-3-,7-4-,13-12+/t15-,16+,17+,19+/m0/s1
type: Species
constant: false
name: 15-epi-lipoxin A5
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#b83b73b0_b4d8_4dbe_98a4_3c07262faa65
units: dimensionless
value: 0.0
type: LocalParameter

metaR ACOATA
name: Acetyl-CoA ACP transacylase
type: Reaction
is described by: http://identifiers.org/pubmed/15507492
product: MODEL1109130000#
is: SBO:0000176
fast: false
is version of: ECO:0000000
reversible: true
notes: GENE_ASSOCIATION: 2194.1 SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.38 Confidence Level: 4 AUTHORS: PMID:11756679,PMID:15507492 NOTES: tv rxn is now charge balanced; removed h - NCD
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.38
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11756679

http://identifiers.org/biomodels.db/MODEL1109130000#_ba993218_1b8c_434b_9519_8c4c34e56256
is: P54868
is encoded by: hsa:3158
constant: false
is: SBO:0000252
initial concentration: NaN
boundary condition: true
initial amount: NaN
has only substance units: false
name: HMGCS2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_02bf3174_0c2a_48a2_841f_44938a943243
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c7ac6d26_a79e_4893_8155_3406188c5f1a
value: 0.0
type: LocalParameter

metaR r2117
is: SBO:0000185
reversible: true
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
type: Reaction
reactant: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1

http://identifiers.org/biomodels.db/MODEL1109130000#_5c94926e_92b4_4df0_a18c_cd275a31dca3
value: -1000.0
type: LocalParameter

metaM Rtotal2 e
notes: FORMULA: CO2FULLR2 CHARGE: -1 INCHI:
name: R total 2 position
initial concentration: 1.0
has only substance units: false
type: Species
is: SBO:0000247
initial amount: NaN
constant: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_7310e416_3d20_4be9_a0bb_ae2451119930
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1ba06024_15db_4e58_a0b5_2a8eb9f187d4
value: -1000.0
type: LocalParameter

metaR PTDCAt
fast: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES: NJ
reversible: true
type: Reaction
is: SBO:0000185
name: fatty acid transport via diffusion
reactant: MODEL1109130000#
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#c2e9947b_56b7_4ed1_a747_0c5207f3cfdf
units: dimensionless
value: 0.0
type: LocalParameter

metaR FA182ACPH
is: SBO:0000176
is version of: http://identifiers.org/ec-code/3.1.2.14
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9159116
name: fatty-acyl-ACP hydrolase
product: MODEL1109130000#
is version of: ECO:0000000
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 55301.1 SUBSYSTEM: Fatty acid oxidation EC Number: 3.1.2.14 Confidence Level: 4 AUTHORS: PMID:9159116 NOTES: NCD
fast: false
reversible: true
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#e17c5b0d_0abc_4885_94ec_f32c2737ade4
value: 0.0
type: LocalParameter

metaR AGTim
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9783918
is version of: ECO:0000269
reversible: false
name: alanine-glyoxylate transaminase (irreversible), mitochondrial
is: SBO:0000176
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: (64902.1) or (64850.1) SUBSYSTEM: Alanine and aspartate metabolism EC Number: 2.6.1.44 Confidence Level: 4 AUTHORS: PMID:15240345,PMID:9038835,PMID:9783918 NOTES: NCD
is described by: http://identifiers.org/pubmed/15240345
is version of: http://identifiers.org/ec-code/2.6.1.44
is described by: http://identifiers.org/pubmed/9038835
modifier: MODEL1109130000#
type: Reaction

metaR RE2151C
reversible: false
name: RE2151
type: Reaction
is version of: http://identifiers.org/ec-code/2.4.1.17
fast: false
product: MODEL1109130000#
is: SBO:0000176
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8295481
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Vitamin A metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:8295481 NOTES:

metaR RE1096C
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10049998
notes: GENE_ASSOCIATION: SUBSYSTEM: Steroid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:10049998,PMID:7578007 NOTES:
fast: false
type: Reaction
name: RE1096
is described by: http://identifiers.org/pubmed/7578007
reversible: false
is: SBO:0000176
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_354bcbf3_afde_4543_b7f8_6b415e9df420
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_09916c5c_3b1a_4020_987f_59a96b59990f
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1C2:ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B1:ATP6V1E1:ATP6V1G2:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_035cf638_ca46_490a_9f9a_4856f60d60f4
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8413cedb_9ff2_4312_8b11_d7c764262c32
value: 1000.0
type: LocalParameter

metaR r0719
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/1550553
is described by: http://identifiers.org/pubmed/10329704
fast: false
name: (S)-3-Hydroxytetradecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.35 EC:1.1.1.211
modifier: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/7150615
is version of: http://identifiers.org/ec-code/1.1.1.35
is described by: http://identifiers.org/pubmed/1651711
reversible: false
is described by: http://identifiers.org/pubmed/8188243
is described by: http://identifiers.org/pubmed/10231530
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8687463
is described by: http://identifiers.org/pubmed/9553139
notes: GENE_ASSOCIATION: 6697.1 SUBSYSTEM: Fatty acid oxidation EC Number: 1.1.1.35 Confidence Level: 0 AUTHORS: PMID:10231530,PMID:10329704,PMID:1550553,PMID:1651711,PMID:7150615,PMID:8188243,PMID:8687463,PMID:9553139 NOTES:
reactant: MODEL1109130000#

metaM C04853 c
is: SBO:0000247
constant: false
type: Species
initial amount: NaN
boundary condition: false
has only substance units: false
notes: FORMULA: C20H31O5 CHARGE: -1 INCHI: InChI=1S/C20H32O5/c21-17-10-6-2-1-3-7-12-18(22)13-8-4-5-9-14-19(23)15-11-16-20(24)25/h3-5,7-9,13-14,18-19,21-23H,1-2,6,10-12,15-17H2,(H,24,25)/p-1/b5-4+,7-3-,13-8+,14-9-/t18-,19-/m1/s1 EHMN_ABBREVIATION: C04853
name: 20-hydroxy-leukotriene B4(1-)
is: HMDB01509
initial concentration: 1.0
is: CHEBI:57460

http://identifiers.org/biomodels.db/MODEL1109130000#_20073bd2_2a0c_4b43_a671_1f45dc150fd1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f2eba937_071d_4659_a8bb_e9d54f0e6ddd
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8ed7dab3_fae1_4c46_9d26_b0926453f75f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ff4a7172_93ae_4ac9_ba9c_d4efdbaf43ec
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dd3904b2_cc68_4d42_8fc6_817dfbb51fa1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9f621aa7_6b14_41b6_b7a3_b4766c3a355b
type: Species
initial amount: NaN
has only substance units: false
boundary condition: true
initial concentration: NaN
name: _AI640625_1_c
is: SBO:0000252
is encoded by: hsa:AI640625
constant: false

metaR r2119
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is described by: http://identifiers.org/pubmed/12739169
reversible: true
product: MODEL1109130000#
fast: false
type: Reaction
modifier: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#b0a42413_5dae_4085_a9cb_c09a67a25e19
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d56b42cc_57ac_4b3c_a288_937e1060d5ab
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d227a88c_b0e7_4e2d_bad5_19a193004f27
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9a75fa9b_6115_40ff_807f_fbe0d987bb7c
value: 0.0
type: LocalParameter

metaM gpi hs r
initial concentration: 1.0
constant: false
initial amount: NaN
boundary condition: false
has only substance units: false
type: Species
notes: FORMULA: C55H106N4O38P4FULLRCO2FULLR2CO2 CHARGE: 0 INCHI:
is: SBO:0000247
name: {[PE-Man-],[PE-]Man},{PE-}Man-GlcN-acylPI

metaR RE0922C
is described by: http://identifiers.org/pubmed/7263841
name: RE0922
is: SBO:0000176
is described by: http://identifiers.org/pubmed/8405382
reactant: MODEL1109130000#
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:7263841,PMID:8405382 NOTES:
reversible: false
fast: false
type: Reaction
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.17

metaR TRPt
is: SBO:0000185
fast: false
name: L-tryptophan transport
reactant: MODEL1109130000#
modifier: MODEL1109130000#
product: MODEL1109130000#
is version of: ECO:0000269
reversible: true
type: Reaction
is described by: http://identifiers.org/pubmed/11827462
notes: GENE_ASSOCIATION: 117247.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:11827462 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_42aa2246_8912_4e36_b88e_ab7bf7f83011
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a0f63438_f3e9_4ab7_bb2a_9f5ad5950e17
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2f69468_0a67_4d3f_a7de_6e6a595d0ad0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_71b28607_3616_43b2_82c0_16b7cea82995
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8ea1e11e_c677_4258_9597_306f740a7f94
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_45d89b19_2dbd_4ec5_9acf_19019941633a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_metaR_EX_fucfuc132galacglcgal14acglcgalgluside_hs_LPAREN_e_RPAREN_
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: V3Fuc,III3Fuc-nLc6Cer exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_2819b600_3beb_41cd_bdec_c86e13999d46
value: 0.0
type: LocalParameter

metaR r2129
reactant: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is: SBO:0000185
product: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
reversible: true
type: Reaction
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169

http://identifiers.org/biomodels.db/MODEL1109130000#_99277f38_f8c8_4ea1_94a0_99ab07c41939
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_58046408_03a9_460a_ac59_5882b6bce294
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_48a3f0cd_e740_4fdc_b91b_069b7d52c6f5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1ff2c119_a027_4358_83e9_b9e2e83b3480
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_068ef1be_6728_410c_bef9_ffc88ac53ce0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_136b3e91_9f19_4514_93cd_819214df72d2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_47e043f8_74b4_4f1e_b65f_f65c6d43ff0e
value: -1000.0
type: LocalParameter

metaM seahcys c
has only substance units: false
initial concentration: 1.0
initial amount: NaN
is: C05692
name: Se-Adenosylselenohomocysteine
notes: FORMULA: C14H20N6O5Se CHARGE: 0 INCHI: InChI=1/C14H20N6O5Se/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6?,7-,9-,10-,13+/m1/s1 EHMN_ABBREVIATION: C05692
is: SBO:0000247
is: http://identifiers.org/pubchem.substance/7999
is: HMDB11117
boundary condition: false
type: Species
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_045abecc_6608_4a3e_b655_c895f92f95f7
type: Species
is: SBO:0000252
name: GAMT
is encoded by: hsa:2593
constant: false
has only substance units: false
is: Q14353
initial amount: NaN
boundary condition: true
initial concentration: NaN

metaM CE2891 c
initial amount: NaN
type: Species
boundary condition: false
has only substance units: false
name: dynorphin B
is: CHEBI:547056
notes: FORMULA: C74H118N21O17 CHARGE: 3 INCHI: InChI=1S/C74H115N21O17/c1-40(2)34-53(91-68(107)54(36-44-18-10-8-11-19-44)86-58(100)39-84-57(99)38-85-62(101)48(76)35-46-25-27-47(97)28-26-46)67(106)89-51(24-17-33-83-74(80)81)63(102)87-50(23-16-32-82-73(78)79)64(103)90-52(29-30-56(77)98)65(104)92-55(37-45-20-12-9-13-21-45)69(108)88-49(22-14-15-31-75)66(105)93-59(41(3)4)70(109)94-60(42(5)6)71(110)95-61(43(7)96)72(111)112/h8-13,18-21,25-28,40-43,48-55,59-61,96-97H,14-17,22-24,29-39,75-76H2,1-7H3,(H2,77,98)(H,84,99)(H,85,101)(H,86,100)(H,87,102)(H,88,108)(H,89,106)(H,90,103)(H,91,107)(H,92,104)(H,93,105)(H,94,109)(H,95,110)(H,111,112)(H4,78,79,82)(H4,80,81,83)/t43-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60+,61+/m1/s1 EHMN_ABBREVIATION: CE2891
initial concentration: 1.0
constant: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#c6470ca5_195d_40a3_bc1c_920432fd80f0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_53d7b2d7_a71a_4548_9936_7ae6efae565c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aa35c0b3_a1cb_4d21_8fec_7ad673a0de43
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a2deab93_1308_4fea_b758_337164e6adc0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_95e98728_1e85_4ae9_be9c_05a7491545d5
units: dimensionless
value: 0.0
type: LocalParameter

metaR NTP3e
type: Reaction
modifier: MODEL1109130000#
name: nucleoside-triphosphatase (GTP)
is: SBO:0000176
notes: GENE_ASSOCIATION: 124583.1 SUBSYSTEM: Nucleotide interconversion EC Number: 3.6.1.15 Confidence Level: 4 AUTHORS: PMID:12234496,PMID:12600208 NOTES:
fast: false
reversible: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12600208
is version of: ECO:0000269
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.6.1.15
is described by: http://identifiers.org/pubmed/12234496

http://identifiers.org/biomodels.db/MODEL1109130000#_948023ea_bcb9_4e7a_a734_6896e4825781
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_10801642_ef18_4b9b_aac1_53b69dc35ee2
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: DPM3:DPM1:DPM2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_1e01b0fb_013e_4c27_bbb4_7f591f5c8a7d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_35760f9b_b72c_4d5b_b161_64b6a76a0cee
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f94495e8_3dd1_4399_94d2_1c2a48f493b7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_360e509c_166e_488d_bbcd_48b2dd880364
type: Species
name: PIK3CA:PIK3R3
has part: P42336
initial concentration: NaN
has part: Q8N381
is: SBO:0000297
is encoded by: hsa:5290
is encoded by: hsa:8503
constant: true
initial amount: NaN
boundary condition: true
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#a7051f66_15d7_4275_b8cf_d190a7c63f05
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be1bb086_2806_4c06_abbb_24dbea27814d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17b01063_e4de_4cd7_acd6_e83d9279891e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c1e61a97_23cf_4e05_8b19_5b67196cb3b0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_58a083e9_1f25_4f59_9834_6dffec67ed2e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7b37ca2c_2e3f_4705_be5b_57cc2d9c4a85
value: -1000.0
type: LocalParameter

metaM hmgcoa m
notes: FORMULA: C27H39N7O20P3S CHARGE: -5 INCHI: InChI=1S/C27H44N7O20P3S/c1-26(2,21(40)24(41)30-5-4-15(35)29-6-7-58-17(38)9-27(3,42)8-16(36)37)11-51-57(48,49)54-56(46,47)50-10-14-20(53-55(43,44)45)19(39)25(52-14)34-13-33-18-22(28)31-12-32-23(18)34/h12-14,19-21,25,39-40,42H,4-11H2,1-3H3,(H,29,35)(H,30,41)(H,36,37)(H,46,47)(H,48,49)(H2,28,31,32)(H2,43,44,45)/p-5/t14-,19-,20-,21+,25-,27+/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00302 EHMN_ABBREVIATION: C00356
is: SBO:0000247
initial concentration: 1.0
constant: false
initial amount: NaN
name: Hydroxymethylglutaryl-CoA
is: HMDB01375
is: CHEBI:15467
boundary condition: false
has only substance units: false
type: Species

metaM gthrd r
notes: FORMULA: C10H16N3O6S CHARGE: -1 INCHI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/p-1/t5-,6-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00056 EHMN_ABBREVIATION: C00051
is: HMDB00125
has only substance units: false
initial amount: NaN
is: CHEBI:57925
initial concentration: 1.0
type: Species
name: glutathionate(1-)
boundary condition: false
is: SBO:0000247
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#b95059c3_d319_439f_a08a_9976f72ef3b4
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

metaR GLCAASE4ly
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 2990.1 SUBSYSTEM: Chondroitin sulfate degradation EC Number: 3.2.1.31 Confidence Level: 4 AUTHORS: PMID:3468507,PMID:3924735,PMID:3987656 NOTES: NCD
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/3468507
is version of: http://identifiers.org/ec-code/3.2.1.31
fast: false
is described by: http://identifiers.org/pubmed/3987656
is: SBO:0000176
name: beta-glucuronidase, lysosomal
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3924735
modifier: MODEL1109130000#
type: Reaction
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_8e03c03d_31ed_4b85_af3f_a12c80889207
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c242f109_5f45_43fc_9481_a000a8796758
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_dbaf1e6f_a82c_4e87_9313_ef575f766b34
is: P48651
is: SBO:0000252
type: Species
has only substance units: false
initial concentration: NaN
name: PTDSS1
boundary condition: true
initial amount: NaN
constant: false
is encoded by: hsa:9791

http://identifiers.org/biomodels.db/MODEL1109130000#_412ca27d_bdb4_424d_975d_b977646d1a40
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_79565a3f_f6e4_4a34_bd5b_855161d4127c
value: -1000.0
type: LocalParameter

metaR AHEXASEly
is version of: http://identifiers.org/ec-code/3.2.1.52
name: beta-N-acetylhexosaminidase, lysosomal
is described by: http://identifiers.org/pubmed/11707436
fast: false
is described by: http://identifiers.org/pubmed/10336991
is: SBO:0000176
type: Reaction
is described by: http://identifiers.org/pubmed/12706724
is version of: ECO:0000000
notes: GENE_ASSOCIATION: (3073.1) or (3074.1) or (3073.1 and 3074.1) SUBSYSTEM: N-glycan degradation EC Number: 3.2.1.52 Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724 NOTES: NCD
reactant: MODEL1109130000#
modifier: MODEL1109130000#
reversible: false
product: MODEL1109130000#

metaR VLCS2r
notes: GENE_ASSOCIATION: 11001.1 SUBSYSTEM: Bile acid synthesis EC Number: 6.2.1.7 Confidence Level: 2 AUTHORS: NOTES: from uniprot and lit - see human recon lit refs divalent cation requirement - unclear which one, reaction inhibited in the presence of EDTA (may just be MgATP or MgATP) - see Kelley and Vessey Biochimica et Biophysica Acta (1994) 1209: 51-55 temporarily will have H+ balance reaction NJ
is: SBO:0000176
reactant: MODEL1109130000#
fast: false
name: Very-long-chain-fatty-acid-CoA ligase
product: MODEL1109130000#
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/6.2.1.7
reversible: false
type: Reaction
is version of: ECO:0000304

http://identifiers.org/biomodels.db/MODEL1109130000#b1a70246_07fb_458a_a583_bccc7f0a2063
units: dimensionless
value: 0.0
type: LocalParameter

metaR G14T14g
is described by: http://identifiers.org/pubmed/3094506
is described by: http://identifiers.org/pubmed/12512857
is described by: http://identifiers.org/pubmed/9405390
is described by: http://identifiers.org/pubmed/3144273
is: SBO:0000176
type: Reaction
is described by: http://identifiers.org/pubmed/1903938
reversible: false
is described by: http://identifiers.org/pubmed/9435216
name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi
product: MODEL1109130000#
fast: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (8703.1) or (8704.2) or (8704.1) or (2683.1) or (9334.1) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.1.38 Confidence Level: 4 AUTHORS: PMID:12512857,PMID:1903938,PMID:3094506,PMID:3144273,PMID:9405390,PMID:9435216 NOTES: Keratan sulfate I biosynthesis NCD
is version of: http://identifiers.org/ec-code/2.4.1.38
is version of: ECO:0000000
reactant: MODEL1109130000#

metaR RE2404R
fast: false
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Miscellaneous EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:10191290 NOTES:
modifier: MODEL1109130000#
reversible: false
type: Reaction
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.4.1.17
name: RE2404
is described by: http://identifiers.org/pubmed/10191290

metaR CSPG Etly
is version of: ECO:0000000
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, lysosomal EC Number: Confidence Level: 2 AUTHORS: NOTES:
type: Reaction
is: SBO:0000185
product: MODEL1109130000#
reversible: false
reactant: MODEL1109130000#
name: chondroitin sulfate E transport, extracellular to lysosome

metaM CE4829 x
is: SBO:0000247
constant: false
boundary condition: false
has only substance units: false
initial amount: NaN
initial concentration: 1.0
notes: FORMULA: C43H64N7O17P3S CHARGE: -4 INCHI: InChI=1/C43H68N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-34(52)71-27-26-45-33(51)24-25-46-41(55)38(54)43(2,3)29-64-70(61,62)67-69(59,60)63-28-32-37(66-68(56,57)58)36(53)42(65-32)50-31-49-35-39(44)47-30-48-40(35)50/h8-9,11-12,14-15,17-18,20-21,30-32,36-38,42,53-54H,4-7,10,13,16,19,22-29H2,1-3H3,(H,45,51)(H,46,55)(H,59,60)(H,61,62)(H2,44,47,48)(H2,56,57,58)/p-4/b9-8-,12-11-,15-14-,18-17-,21-20-/t32-,36+,37+,38u,42-/m0/s1 EHMN_ABBREVIATION: CE4829
type: Species
name: adrenoyl-CoA

metaR GP1CALPHAtg
is: SBO:0000185
reversible: true
is version of: ECO:0000000
name: gp1calpha hs intracellular transport
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, golgi apparatus EC Number: Confidence Level: 1 AUTHORS: PMID:8206147 NOTES: unknown mechanism for transport - intracellular transport occurs, most details are unknown - see for example Varki glycobiology text or numerous reviews (PMID: 8206147) NJ
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8206147
fast: false
product: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_8934be01_e34c_455f_840d_15fee0cad653
is: B3KWF4
name: GALNT11
is: SBO:0000252
type: Species
initial concentration: NaN
is encoded by: hsa:63917
has only substance units: false
constant: true
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_1c03d76e_daa4_4f18_957b_4417a96ed1d5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_441891cb_8440_4c11_819c_09890902495f
has only substance units: false
name: SI
is encoded by: hsa:6476
constant: false
type: Species
is: P14410
boundary condition: true
is: SBO:0000252
initial concentration: NaN
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_70e143b9_bc92_46b0_958d_ce84b2770479
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1G3:ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V1C1:ATP6V1E1:ATP6V1F
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#fb499023_5199_44f1_a50e_4053037a3040
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4d61791e_ad0a_4354_8f31_90acc31eca60
type: Species
is encoded by: hsa:343
constant: false
is: SBO:0000252
initial concentration: NaN
boundary condition: true
name: AQP8
has only substance units: false
is: O94778
initial amount: NaN

metaR r2125
reversible: true
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
modifier: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
fast: false
reactant: MODEL1109130000#
type: Reaction
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_54fc0930_10fe_4254_88d3_776ced4281d5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b3f2d614_73bc_44fb_b43c_bff03874c1b7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1baa580e_4bca_41cd_bfe3_0b05b836fbec
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_50e7dbf0_2b09_4ef1_b3de_7e769ab69720
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_05f553a8_482b_45d8_b978_32bc299e7aaa
value: 1000.0
type: LocalParameter

metaM s2l2fn2m2masn e
has only substance units: false
is: SBO:0000247
constant: false
name: PA6
type: Species
initial amount: NaN
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C90H145N6O65X CHARGE: -2 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#_35f7d5c9_38f0_4592_9bc3_c653243a5fcd
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5bcf49af_e81f_420c_82c3_fd560bc40370
units: dimensionless
value: 0.0
type: LocalParameter

metaR r2126
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
type: Reaction
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
fast: false
reversible: true
is: SBO:0000185
product: MODEL1109130000#
reactant: MODEL1109130000#

metaM 3snpyr m
initial concentration: 1.0
is: CHEBI:1665
type: Species
notes: FORMULA: C3H2O5S CHARGE: -2 INCHI: InChI=1S/C3H4O5S/c4-2(3(5)6)1-9(7)8/h1H2,(H,5,6)(H,7,8) EHMN_ABBREVIATION: C05527
is: HMDB02332
has only substance units: false
name: 3-Sulfinopyruvate
constant: false
is: SBO:0000247
initial amount: NaN
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#cdf2422b_fb7c_4053_b78c_da6ccb7d26aa
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_50d6f906_3425_4f32_a9e8_8d98316f7fed
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be5a1123_5f7a_4a43_b9e6_547c09fd4435
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0ab79d9f_9c9c_4584_83b9_03bd8f2db1c2
value: 1000.0
type: LocalParameter

metaM pail345p hs c
constant: false
has only substance units: false
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C9H13O18P4FULLRCO2FULLR2CO2 CHARGE: -7 EHMN_ABBREVIATION: C05981 INCHI:
type: Species
boundary condition: false
name: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-)
initial amount: NaN
is: CHEBI:57836

http://identifiers.org/biomodels.db/MODEL1109130000#_6c576c96_23d9_402a_9e72_686b30294c29
value: 0.0
type: LocalParameter

metaM 9 cis retfa e
boundary condition: false
is: SBO:0000247
has only substance units: false
constant: false
name: fatty acid 9-cis-retinol
type: Species
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C20H29OFULLR2CO CHARGE: 0

metaR r2127
reversible: true
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is described by: http://identifiers.org/pubmed/12739169
product: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
reactant: MODEL1109130000#
type: Reaction
is: SBO:0000185

metaM CE2416 x
constant: false
initial amount: NaN
is: SBO:0000247
name: (2R,6S,10S)-pristanate
boundary condition: false
has only substance units: false
initial concentration: 1.0
type: Species
notes: FORMULA: C19H37O2 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE2416

http://identifiers.org/biomodels.db/MODEL1109130000#_53a16d0d_d0fe_4401_b29b_183cfc1fe4e4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1b8689cc_c811_4dc1_9eae_d4c5772f6c56
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_19a2bb4b_d919_44b7_bbb5_621acc238c3f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8c722c50_11eb_496f_8e33_a073976b283b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c2ca3238_6789_4672_bd32_e1d9b22fa0e7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_846a8a26_bc39_4f87_a0ae_c925bd2c9efa
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8734b83e_c09a_4db4_acf8_355918732e15
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_42193c02_0fbd_4391_933e_eb625afa7331
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_72aa3cf2_8d62_47ed_8114_07f5a9bb0483
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_555af971_b7f4_4f20_8292_55b2d50e7660
value: 0.0
type: LocalParameter

metaM s2l2fn2m2masn g
boundary condition: false
name: PA6
is: SBO:0000247
constant: false
initial amount: NaN
type: Species
initial concentration: 1.0
has only substance units: false
notes: FORMULA: C90H145N6O65X CHARGE: -2 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#afcaddd1_0740_4c60_bf61_8759150c33ed
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6fde842f_080d_4095_afd9_00a9d7c7404e
boundary condition: true
initial concentration: NaN
is: SBO:0000252
type: Species
is encoded by: hsa:11238
initial amount: NaN
name: CA5B
is: Q9Y2D0
constant: false
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#ee9e21ba_fa80_42f0_9591_f1c21b19fe84
value: 1000.0
type: LocalParameter

metaR EX thmtp LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Thiamin triphosphate exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_7d37f2fb_69d1_4ee7_b335_b9c1bcd224b7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69cb4c09_6111_4b36_b7be_1cd373f1215c
value: 1000.0
type: LocalParameter

metaR EX psyltdechol LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000176
fast: false
reversible: true
name: exchange reaction for psyllium-taurodeoxycholic acid complex
type: Reaction

metaR r2128
product: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
is: SBO:0000185
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
type: Reaction
fast: false

metaR OROTGLUt
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: AUTHORS: NOTES:
is: SBO:0000185
fast: false
reversible: true
name: OROTGLUt
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_86013fac_a211_40d7_9cb3_4a4b66e38910
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_64bfee41_e067_4a04_93e1_bce448371e7a
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1862
product: MODEL1109130000#
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/14770310
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
reversible: false
is: SBO:0000185
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
name: Y+LAT2 Utilized transport

metaM ksii core2 pre7 g
type: Species
boundary condition: false
constant: false
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C67H108N5O51SX CHARGE: -2 INCHI:
name: keratan sulfate II biosynthesis, precursor 7
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#ed7139b3_95ee_4b00_b400_c54b106831c5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_41136a30_457b_42fa_8fb3_0b010e53c20b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f8fc04d_0103_4f61_84a6_9b7e5187bd3e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a7f970c1_1a9e_436b_81fe_12c03a7f8b06
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a7db9127_5d6f_4de9_b545_20862c425768
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_471b4e45_cf03_414f_866a_3e0912720bad
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bb292aaf_dccd_450f_8272_712518207547
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5e2c920a_beb6_4eb5_8659_c0a1e01255fa
value: -1000.0
type: LocalParameter

metaM pail345p hs g
type: Species
has only substance units: false
is: SBO:0000247
is: CHEBI:57836
name: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-)
initial concentration: 1.0
constant: false
initial amount: NaN
boundary condition: false
notes: FORMULA: C9H13O18P4FULLRCO2FULLR2CO2 CHARGE: -7 EHMN_ABBREVIATION: C05981 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#aee6dc2f_f729_40a2_a45f_359ce3c7e89d
units: dimensionless
value: 0.0
type: LocalParameter

metaM hmgcoa r
notes: FORMULA: C27H39N7O20P3S CHARGE: -5 INCHI: InChI=1S/C27H44N7O20P3S/c1-26(2,21(40)24(41)30-5-4-15(35)29-6-7-58-17(38)9-27(3,42)8-16(36)37)11-51-57(48,49)54-56(46,47)50-10-14-20(53-55(43,44)45)19(39)25(52-14)34-13-33-18-22(28)31-12-32-23(18)34/h12-14,19-21,25,39-40,42H,4-11H2,1-3H3,(H,29,35)(H,30,41)(H,36,37)(H,46,47)(H,48,49)(H2,28,31,32)(H2,43,44,45)/p-5/t14-,19-,20-,21+,25-,27+/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00302 EHMN_ABBREVIATION: C00356
name: Hydroxymethylglutaryl-CoA
has only substance units: false
initial amount: NaN
constant: false
boundary condition: false
initial concentration: 1.0
type: Species
is: CHEBI:15467
is: HMDB01375
is: SBO:0000247

metaR r1863
reversible: false
is: SBO:0000185
type: Reaction
modifier: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/14770309
name: Y+LAT2 Utilized transport
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:

metaM CE6185 x
constant: false
is: SBO:0000247
boundary condition: false
name: omega-carboxy-trinor-leukotriene B4
initial concentration: 1.0
notes: FORMULA: C18H24O6 CHARGE: -2 INCHI: InChI=1/C18H26O6/c19-15(11-6-3-7-13-17(21)22)9-4-1-2-5-10-16(20)12-8-14-18(23)24/h1-6,9-10,15-16,19-20H,7-8,11-14H2,(H,21,22)(H,23,24)/p-2/b2-1+,6-3-,9-4+,10-5-/t15-,16+/m1/s1 EHMN_ABBREVIATION: CE6185
initial amount: NaN
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#aea0d66b_7b29_4396_bd36_f0bca9595c9d
value: 1000.0
type: LocalParameter

metaR RE3227C
is described by: http://identifiers.org/pubmed/10970790
reactant: MODEL1109130000#
fast: false
is: SBO:0000176
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
product: MODEL1109130000#
type: Reaction
reversible: true
name: RE3227

http://identifiers.org/biomodels.db/MODEL1109130000#fae80a3f_ab84_4e6c_b6b8_5ce6a0c991b4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_81226ec5_bd4a_4eb2_ba9d_9eaee8fd5ed1
initial concentration: NaN
constant: false
is encoded by: hsa:6520
type: Species
is: SBO:0000297
has only substance units: false
is encoded by: hsa:56301
has part: P08195
boundary condition: true
initial amount: NaN
has part: Q9NS82
name: SLC7A10:SLC3A2

http://identifiers.org/biomodels.db/MODEL1109130000#_7f9f8bf3_58fa_4037_b6eb_648f14ff3d9a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a98bebdb_a84c_46b2_8564_893c6cefcc79
value: 0.0
type: LocalParameter

metaM CE2881 r
notes: FORMULA: C14H7I4O4 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE2881
has only substance units: false
boundary condition: false
constant: false
is: SBO:0000247
type: Species
initial amount: NaN
initial concentration: 1.0
name: 3,5,3,5-tetraiodothyroacetate

metaM urcan c
constant: false
initial amount: NaN
is: C00785
type: Species
has only substance units: false
is: CHEBI:17771
initial concentration: 1.0
is: HMDB00301
name: Urocanate
is: SBO:0000247
notes: FORMULA: C6H5N2O2 CHARGE: -1 HEPATONET_1.0_ABBREVIATION: HC00534 EHMN_ABBREVIATION: C00785 INCHI: InChI=1S/C6H6N2O2/c9-6(10)2-1-5-3-7-4-8-5/h1-4H,(H,7,8)(H,9,10)/p-1/b2-1+
boundary condition: false

metaR r1860
is: SBO:0000185
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
fast: false
is described by: http://identifiers.org/pubmed/14770310
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
type: Reaction
reactant: MODEL1109130000#
modifier: MODEL1109130000#
name: Y+LAT2 Utilized transport

http://identifiers.org/biomodels.db/MODEL1109130000#f598d1f7_b487_4ba7_a248_d23719000679
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d534f069_1633_4333_908a_cefb85cf6bcb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d5cb95d5_c8a3_4c2c_8296_4b4535eb67ac
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_379f94b7_bad1_4ac7_a558_59f4073c8542
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_391dd0f7_9d79_41ad_bca7_9c04857ad00d
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cc208aa4_dda7_4677_99ed_5c75737b6d1e
value: 0.0
type: LocalParameter

metaR GP1CALPHAte
reactant: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 1 AUTHORS: PMID:8206147 NOTES: unknown mechanism for transport - intracellular transport occurs, most details are unknown - see for example Varki glycobiology text or numerous reviews (PMID: 8206147) - extracellular transport is also made available since metabolites can get to outer plasma membrane NJ
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/8206147
name: gp1calpha hs transport
product: MODEL1109130000#
is: SBO:0000185
fast: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#f24f13d3_28ac_4eb8_9a23_f1d2cbff3133
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c48aa440_0f42_4ee0_9fae_8f2975c553c9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ddfd6c3f_516b_433d_90eb_28fac9f7b073
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#db3c4f3b_1a24_4ed0_aa45_8d9ad635735f
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69712538_ce15_4bd7_b2b9_3e4bd78abd0a
value: 0.0
type: LocalParameter

metaR r1861
modifier: MODEL1109130000#
is: SBO:0000185
type: Reaction
reactant: MODEL1109130000#
fast: false
name: Y+LAT2 Utilized transport
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#c8f20a61_7b6f_48a9_b586_38887cbecfa9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_506a8252_a1fc_4d15_b548_633279b20c39
value: 0.0
type: LocalParameter

metaM n2m2nm c
notes: FORMULA: C58H97N5O41 CHARGE: 0 INCHI:
boundary condition: false
initial amount: NaN
has only substance units: false
constant: false
is: SBO:0000247
type: Species
initial concentration: 1.0
name: n2m2nmasn (w/o peptide linkage)

http://identifiers.org/biomodels.db/MODEL1109130000#_9049d141_80a2_4278_afad_91e0c593410a
value: -1000.0
type: LocalParameter

metaR GCALDD
reactant: MODEL1109130000#
product: MODEL1109130000#
name: Glycolaldehyde dehydrogenase
type: Reaction
notes: GENE_ASSOCIATION: (218.1) or (223.1) or (8854.2) or (224.1) or (222.1) or (8854.1) or (221.1) or (216.1) or (8854.3) or (501.1) or (220.1) SUBSYSTEM: Glyoxylate and dicarboxylate metabolism EC Number: 1.2.1.21 Confidence Level: 2 AUTHORS: PMID:11434452 NOTES: JLR
is: SBO:0000176
modifier: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/11434452
fast: false
is version of: http://identifiers.org/ec-code/1.2.1.21
is version of: ECO:0000304

http://identifiers.org/biomodels.db/MODEL1109130000#_82df51fa_ea98_4485_aec1_fc87a540b3cf
boundary condition: true
type: Species
initial amount: NaN
initial concentration: NaN
constant: true
is: SBO:0000252
is encoded by: hsa:H77542
has only substance units: false
name: null

http://identifiers.org/biomodels.db/MODEL1109130000#_995a57fa_1f78_40ab_ad5c_cd845f8ee3c2
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3ee40a88_d419_4873_9b6d_79718957531a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7abfcbad_d643_4f1c_9196_de172d8c7b8d
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ac446638_490b_46fc_b91d_24f4968e6a31
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

metaM 4mzym int1 r
name: 4-Methylzymosterol intermediate 1
boundary condition: false
initial concentration: 1.0
initial amount: NaN
constant: false
notes: FORMULA: C29H46O3 CHARGE: 0 INCHI: InChI=1/C29H46O3/c1-18(2)8-7-9-19(3)21-11-12-22-20-10-13-24-28(5,23(20)14-16-27(21,22)4)17-15-25(30)29(24,6)26(31)32/h8,19,21-22,24-25,30H,7,9-17H2,1-6H3,(H,31,32)/t19-,21?,22?,24?,25-,27+,28+,29-/m0/s1
has only substance units: false
type: Species
is: HMDB06927
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#d8f013ae_87a3_4845_a601_1758c62b83b4
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G2:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#b701d2e0_659d_4464_8880_88a753855755
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_98705b22_782f_49bf_998d_531c67811001
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7bf401f0_af39_4541_8585_d1e1602843f7
units: dimensionless
value: 0.0
type: LocalParameter

metaM C14768 r
is: C14768
is: SBO:0000247
has only substance units: false
constant: false
notes: FORMULA: C20H31O3 CHARGE: -1 INCHI: InChI=1/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-10,12-13,18-19H,2-5,8,11,14-17H2,1H3,(H,21,22)/b7-6-,10-9-,13-12- EHMN_ABBREVIATION: C14768
initial concentration: 1.0
initial amount: NaN
name: 5,6-EET
is: HMDB02190
type: Species
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_1dc9992f_d146_4fe4_bb55_fbe1730ec68e
is encoded by: hsa:239
has only substance units: false
boundary condition: true
is: SBO:0000252
type: Species
initial concentration: NaN
is: P18054
name: ALOX12
constant: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#f6918f91_b625_4cbe_94ae_fb079ebbaa58
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_54bcb02f_14bd_435c_8a4c_a631f83ca29b
units: dimensionless
value: 0.0
type: LocalParameter

metaR P4501B1r
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8910454
is: SBO:0000176
fast: false
type: Reaction
notes: GENE_ASSOCIATION: 1545.1 SUBSYSTEM: Steroid metabolism EC Number: 1.14.14.1 Confidence Level: 4 AUTHORS: PMID:15579107,PMID:8910454 NOTES: _4 hydroxylation of 17 beta estradiol NJ
product: MODEL1109130000#
reversible: false
name: cytochrome P450 1B1
is version of: ECO:0000269
is version of: http://identifiers.org/ec-code/1.14.14.1
is described by: http://identifiers.org/pubmed/15579107
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_38bef28d_7e56_4d8a_bac4_bc292251b56e
units: dimensionless
value: 0.0
type: LocalParameter

metaR ENMAN5g
name: Endomannosidase (m6masnB2-producing), Golgi apparatus
fast: false
product: MODEL1109130000#
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: N-glycan synthesis EC Number: Confidence Level: 0 AUTHORS: NOTES: NCD
is: SBO:0000176
type: Reaction
reactant: MODEL1109130000#
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_46308f4e_31c3_4584_b9e5_0071951a0da6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74eedf60_d247_46ad_9f69_5e42c3687f29
is encoded by: hsa:64850
is: Q8TBG4
type: Species
is: SBO:0000252
constant: false
boundary condition: true
name: AGXT2L1
has only substance units: false
initial amount: NaN
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_81b44ee0_fddb_4365_82e8_2856560c5377
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a29a3d20_e072_438c_abb5_139b3743fdde
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#baba4edb_337e_4db9_a673_07bc02a4f775
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2d2b6330_bece_4a49_9e8a_f4d9ad6d3fc7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dad5d2d8_168a_4742_a553_fe347662d1c4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_fbf9fdc1_d7ba_4b28_aa81_2e8f974f65b1
has only substance units: false
constant: false
name: SETD7
is: SBO:0000252
initial concentration: NaN
is: Q8WTS6
is encoded by: hsa:80854
initial amount: NaN
type: Species
boundary condition: true
notes: DRUGBANK_UNKNOWN: DB01752

metaR NICRNTtn
is: SBO:0000185
reactant: MODEL1109130000#
is version of: ECO:0000000
fast: false
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, nuclear EC Number: Confidence Level: 2 AUTHORS: NOTES: it
type: Reaction
product: MODEL1109130000#
name: NICRNT transport, nuclear trhough pore

http://identifiers.org/biomodels.db/MODEL1109130000#_d7ea15d0_e2a9_4215_9097_d8f89db6b45e
has only substance units: false
boundary condition: true
is: SBO:0000252
type: Species
constant: false
is encoded by: hsa:AA576959
initial amount: NaN
name: _AA576959_1_c
initial concentration: NaN

metaR RE0922R
reactant: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
reversible: false
is version of: http://identifiers.org/ec-code/2.4.1.17
fast: false
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:7263841,PMID:8405382 NOTES:
is described by: http://identifiers.org/pubmed/8405382
modifier: MODEL1109130000#
is: SBO:0000176
name: RE0922
is described by: http://identifiers.org/pubmed/7263841

http://identifiers.org/biomodels.db/MODEL1109130000#d2ad4c64_1c2e_44b3_9671_94a4d1a4332c
value: 1000.0
type: LocalParameter

metaR IVCRNe
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 2 AUTHORS: Jones LL, McDonald DA, Borum PR. (2010). Progress in Lipid Research 49: 61-75 EC Number: NOTES: elevated in beta kto thiolase deficiency, SCAD GENE_ASSOCIATION:
is: SBO:0000185
fast: false
reversible: false
name: transport of isovaleryl carnitine into the extra cellular space
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#a4435557_14d2_425b_9d5d_6bec17a3c9ba
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_845b5ea8_c5e9_4899_a36a_e910d1b73cc9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_427a0271_bbd1_4ce5_a0f9_5dce6b7102bc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_798cfc15_626b_4d57_bfa9_8018beff4ff0
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX 3aib LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: L-3-Amino-isobutanoate exchange
type: Reaction

metaM gthrd m
initial amount: NaN
is: SBO:0000247
initial concentration: 1.0
type: Species
is: CHEBI:57925
notes: FORMULA: C10H16N3O6S CHARGE: -1 INCHI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/p-1/t5-,6-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00056 EHMN_ABBREVIATION: C00051
constant: false
name: glutathionate(1-)
has only substance units: false
boundary condition: false
is: HMDB00125

http://identifiers.org/biomodels.db/MODEL1109130000#_2adc5dd9_3960_48ff_a7d8_80babdd508e9
constant: true
is: SBO:0000252
initial concentration: NaN
is: O60760
has only substance units: false
type: Species
initial amount: NaN
name: HPGDS
is encoded by: hsa:27306
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#e58416ca_30f3_4e4a_b6b1_9d6ca64eacac
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_235f414c_71f2_47e9_9adc_7258a54ed7d5
units: dimensionless
value: 0.0
type: LocalParameter

metaM hmgcoa x
initial concentration: 1.0
is: SBO:0000247
name: Hydroxymethylglutaryl-CoA
has only substance units: false
constant: false
is: HMDB01375
boundary condition: false
type: Species
is: CHEBI:15467
initial amount: NaN
notes: FORMULA: C27H39N7O20P3S CHARGE: -5 INCHI: InChI=1S/C27H44N7O20P3S/c1-26(2,21(40)24(41)30-5-4-15(35)29-6-7-58-17(38)9-27(3,42)8-16(36)37)11-51-57(48,49)54-56(46,47)50-10-14-20(53-55(43,44)45)19(39)25(52-14)34-13-33-18-22(28)31-12-32-23(18)34/h12-14,19-21,25,39-40,42H,4-11H2,1-3H3,(H,29,35)(H,30,41)(H,36,37)(H,46,47)(H,48,49)(H2,28,31,32)(H2,43,44,45)/p-5/t14-,19-,20-,21+,25-,27+/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00302 EHMN_ABBREVIATION: C00356

http://identifiers.org/biomodels.db/MODEL1109130000#_38704504_c40f_4698_8891_b97552db39f3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_117f0199_3d36_420d_9ff6_8b69fcbb2ef0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9599f33d_0126_4a6c_9c84_f26f07fc3bae
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f3e2df78_4815_4dc0_a5aa_b7bf074e3f1d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_36590957_72cc_4d36_9b7a_9ae78c94b066
value: 0.0
type: LocalParameter

metaR EX ala L LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for L-alanine
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_9ef24c5d_56ff_4d91_a061_62a6b1e81287
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_71a5bddd_c05b_4028_82ea_1bb7e672378e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a2e755f5_704a_4c85_a43f_c06cc385c570
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_49f640d9_f84b_40c5_9fda_712f50f8d038
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cbed3fe8_70ac_4941_a0a9_bcfe1d0a201b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4e95133e_49ad_4a38_9cb8_b2ac16335c08
has part: Q9HCC0
is: SBO:0000297
is encoded by: hsa:64087
boundary condition: true
is encoded by: hsa:56922
has part: Q96RQ3
initial amount: NaN
constant: true
name: MCCC1:MCCC2
initial concentration: NaN
has only substance units: false
type: Species

metaR r1859
type: Reaction
name: Y+LAT2 Utilized transport
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
reactant: MODEL1109130000#
modifier: MODEL1109130000#
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
reversible: false
is: SBO:0000185

metaM hs deg9 l
has only substance units: false
type: Species
notes: FORMULA: C61H87N3O76S8 CHARGE: -10 INCHI:
initial amount: NaN
constant: false
boundary condition: false
initial concentration: 1.0
is: SBO:0000247
name: heparan sulfate, degradation product 9

metaR FA140ACPH
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 55301.1 SUBSYSTEM: Fatty acid oxidation EC Number: 3.1.2.14 Confidence Level: 4 AUTHORS: PMID:9159116 NOTES: NCD rxn is now charge balanced - NCD
name: fatty-acyl-ACP hydrolase
reactant: MODEL1109130000#
fast: false
reversible: true
is version of: http://identifiers.org/ec-code/3.1.2.14
type: Reaction
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9159116
is: SBO:0000176
is version of: ECO:0000269

http://identifiers.org/biomodels.db/MODEL1109130000#_71f7381b_63db_4feb_b131_19f726c829e0
value: 1000.0
type: LocalParameter

metaM pail345p hs n
boundary condition: false
constant: false
is: SBO:0000247
name: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-)
has only substance units: false
type: Species
is: CHEBI:57836
initial concentration: 1.0
notes: FORMULA: C9H13O18P4FULLRCO2FULLR2CO2 CHARGE: -7 EHMN_ABBREVIATION: C05981 INCHI:
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_9eeb3f39_bea4_4dc5_b781_73aaeb2fc12d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0cc9bad8_d3b1_490e_98e8_2c9fea46d537
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a83f014a_6c1e_4e98_a127_165b2df1f471
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4615f785_ba5b_4a36_bb68_13d22f4bc28e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4201636f_9dbb_4cea_b8ba_2f366f56bc5e
value: 0.0
type: LocalParameter

metaR r1858
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
fast: false
name: Y+LAT2 Utilized transport
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
type: Reaction
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_69f5659c_2dee_4acc_b9bf_936033dfa6db
value: 1000.0
type: LocalParameter

metaR EX chsterol LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for cholesterol
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_6991c169_5160_4097_8b41_1da995255fed
value: 1000.0
type: LocalParameter

metaR ACNAM9PL2
notes: GENE_ASSOCIATION: 54187.1 SUBSYSTEM: Aminosugar metabolism EC Number: 2.5.1.56 Confidence Level: 4 AUTHORS: PMID:10749855 NOTES: EC-2.5.1.56 NCD
type: Reaction
is version of: http://identifiers.org/ec-code/2.5.1.56
product: MODEL1109130000#
reactant: MODEL1109130000#
is version of: ECO:0000000
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/10749855
name: N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating)
fast: false
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#f84e44b0_fdef_46e1_8646_535de3ef0ccd
value: -1000.0
type: LocalParameter

metaR RE2405C
reactant: MODEL1109130000#
reversible: false
type: Reaction
modifier: MODEL1109130000#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.4.1.17
name: RE2405
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10191290
fast: false
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Miscellaneous EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:10191290 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_0b14b412_96a6_4368_a89d_259255bc9d0c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_81e500de_1445_4c84_923a_c902f0dd294e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0197eb53_c93a_4335_a89c_6ccb9998bedf
type: Species
name: PNLIPRP1
constant: true
is: SBO:0000252
has only substance units: false
initial amount: NaN
is: P54315
boundary condition: true
is encoded by: hsa:5407
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_4db0d8a9_ece7_4db3_8681_dc607d0bf8d4
value: 1000.0
type: LocalParameter

metaR RE1050C
type: Reaction
fast: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.11.1.7
is described by: http://identifiers.org/pubmed/11013238
name: RE1050
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (7173.1) or (9588.1) SUBSYSTEM: Miscellaneous EC Number: 1.11.1.7 Confidence Level: 0 AUTHORS: PMID:11013238 NOTES:
modifier: MODEL1109130000#
is: SBO:0000176
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_72ddac64_0e4c_44db_98ea_0a902ef52625
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2bf9d06b_fc39_4f2f_9722_a57c923dff3a
value: 0.0
type: LocalParameter

metaM n2m2nm l
initial amount: NaN
notes: FORMULA: C58H97N5O41 CHARGE: 0 INCHI:
constant: false
has only substance units: false
initial concentration: 1.0
name: n2m2nmasn (w/o peptide linkage)
boundary condition: false
type: Species
is: SBO:0000247

metaR r1857
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
reversible: false
modifier: MODEL1109130000#
name: Y+LAT2 Utilized transport

metaM dmgly m
initial concentration: 1.0
is: SBO:0000247
boundary condition: false
is: CHEBI:17724
has only substance units: false
initial amount: NaN
type: Species
name: N,N-dimethylglycine
constant: false
is: HMDB00092
notes: FORMULA: C4H9NO2 CHARGE: 0 INCHI: InChI=1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7) EHMN_ABBREVIATION: C01026

metaR NACHEX2ly
type: Reaction
is version of: http://identifiers.org/ec-code/3.2.1.52
is described by: http://identifiers.org/pubmed/10336991
is described by: http://identifiers.org/pubmed/8993162
fast: false
notes: GENE_ASSOCIATION: (3073.1 and 3074.1) or (3073.1) or (3074.1) SUBSYSTEM: Chondroitin sulfate degradation EC Number: 3.2.1.52 Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: NCD
is described by: http://identifiers.org/pubmed/11707436
name: beta-N-acetylhexosaminidase, lysosomal
reactant: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/12706724
modifier: MODEL1109130000#
product: MODEL1109130000#
is: SBO:0000176
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#b0d74c64_8195_42c0_b76c_a28af2f20555
value: 1000.0
type: LocalParameter

metaM HC01651 n
is: SBO:0000247
is: C05922
initial concentration: 1.0
is: http://identifiers.org/pubchem.substance/8210
constant: false
has only substance units: false
name: Formamidopyrimidine nucleoside triphosphate
type: Species
initial amount: NaN
boundary condition: false
notes: FORMULA: CHARGE: 0 EHMN_ABBREVIATION: C05922

metaM ksii core4 pre5 g
constant: false
is: SBO:0000247
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C69H112N6O48X CHARGE: -1 INCHI:
boundary condition: false
name: keratan sulfate II biosynthesis, precursor 5
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_43cf400e_85e9_4c55_be39_0a2a473e5027
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74fd96cc_f9f1_4e47_be70_73fc318ad691
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24d61fe6_795b_4dd4_a22c_34210fa7e4b8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2c174624_4116_45b1_9c70_f28bf1515259
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a36d8905_3930_4b9c_b7f0_197209095562
is: SBO:0000252
initial amount: NaN
type: Species
constant: false
name: _U37519_1_c
has only substance units: false
boundary condition: true
is encoded by: hsa:U37519
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_d90f41a8_4e6c_4188_8847_e22bb506296f
boundary condition: true
is: SBO:0000252
initial amount: NaN
is: Q9NVE7
initial concentration: NaN
has only substance units: false
constant: false
name: PANK4
type: Species
is encoded by: hsa:55229

http://identifiers.org/biomodels.db/MODEL1109130000#d378aed4_3f5d_460b_a48a_4ae2ce5d4b21
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4ff454e4_e17c_42fb_83f2_25d8e2974601
value: 0.0
type: LocalParameter

metaR r1856
modifier: MODEL1109130000#
type: Reaction
name: Y+LAT2 Utilized transport
reversible: false
fast: false
is: SBO:0000185
is described by: http://identifiers.org/pubmed/14770309
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
reactant: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310

http://identifiers.org/biomodels.db/MODEL1109130000#e258d0ff_1fb0_41d3_ab2c_7dc7e597d8b5
value: 0.0
type: LocalParameter

metaM CE2416 c
name: (2R,6S,10S)-pristanate
boundary condition: false
initial concentration: 1.0
type: Species
notes: FORMULA: C19H37O2 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE2416
initial amount: NaN
constant: false
is: SBO:0000247
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#ae2d7586_196f_4397_a10e_b20577e0e179
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_383cb01b_8d88_455c_af59_add429424a14
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_20447479_f01b_430b_8806_ecb66b26e4aa
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18caf244_0707_4c97_9a9f_f5733fd1bb6c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31a64190_cfc8_4c2b_853c_f0caecf907ad
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8622c96_17b6_4e0e_a5e4_7beedcd8157a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d26804ae_12d7_4148_a493_30e5b1e45345
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: VNN3:VNN2:VNN1
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_8de1292f_db91_4e8c_9733_f89599096e68
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6c2f8caa_1ba0_47f3_b93c_780380f4dac5
value: -1000.0
type: LocalParameter

metaR r1855
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#
type: Reaction
reversible: false
is: SBO:0000185
name: Y+LAT2 Utilized transport
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770310
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309

http://identifiers.org/biomodels.db/MODEL1109130000#_94f1f561_36c8_416f_923d_75ea46cc3071
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c0d8e417_a6cb_4d2f_b7fd_4b2377af652a
value: 1000.0
type: LocalParameter

metaM seahcys n
initial concentration: 1.0
boundary condition: false
is: HMDB11117
name: Se-Adenosylselenohomocysteine
is: C05692
notes: FORMULA: C14H20N6O5Se CHARGE: 0 INCHI: InChI=1/C14H20N6O5Se/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6?,7-,9-,10-,13+/m1/s1 EHMN_ABBREVIATION: C05692
type: Species
has only substance units: false
constant: false
initial amount: NaN
is: http://identifiers.org/pubchem.substance/7999
is: SBO:0000247

metaM pail345p hs r
initial concentration: 1.0
is: CHEBI:57836
has only substance units: false
initial amount: NaN
constant: false
is: SBO:0000247
name: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-)
type: Species
notes: FORMULA: C9H13O18P4FULLRCO2FULLR2CO2 CHARGE: -7 EHMN_ABBREVIATION: C05981 INCHI:
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4d5fa63e_9fb1_4269_a35b_50dc742dec4d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_58cad16a_9a64_4cd8_a2b5_650d9936b51c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_824be5da_56c2_424c_9474_583585ce1cc8
value: 0.0
type: LocalParameter

metaR EX CE5787 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: kinetensin 1-3 exchange
type: Reaction

metaR r1854
type: Reaction
name: Y+LAT2 Utilized transport
reversible: false
fast: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310

http://identifiers.org/biomodels.db/MODEL1109130000#_8eb67562_7c35_4421_bb05_349bd416b5c3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_70237424_5b34_4dba_a9ac_1ad161c8a986
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cef1f2d1_cf6e_46a9_9223_5b9e41e93d4a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4cd09246_fd5e_4aff_b94a_b018d8fad95d
name: SLC38A5
constant: false
initial amount: NaN
initial concentration: NaN
boundary condition: true
type: Species
is: Q8WUX1
is encoded by: hsa:92745
is: SBO:0000252
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_8cc6f994_9864_48be_96a9_b956247ca8bb
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6d10e7d1_2e14_4bc5_ad7a_4b1b077c9a74
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8e182977_6a8a_4bde_bd50_084bfa35d996
value: 1000.0
type: LocalParameter

metaR r1853
fast: false
reactant: MODEL1109130000#
type: Reaction
name: Y+LAT2 Utilized transport
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
is described by: http://identifiers.org/pubmed/14770309
reversible: false
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_29bf026b_ac39_4460_bd34_24e9e2366075
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6fa27c11_97ef_4f73_8e49_b1b4dad2a09a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_39fe77c7_c68a_4de9_b59f_4a7516f66daa
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f0f76b58_cecc_456c_ab1e_a52f9039ee5b
value: 1000.0
type: LocalParameter

metaM L2aadp m
notes: FORMULA: C6H10NO4 CHARGE: -1 INCHI: InChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/p-1/t4-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00599 EHMN_ABBREVIATION: C00956
is: CHEBI:58672
name: L-2-aminoadipate(1-)
is: HMDB00510
boundary condition: false
initial concentration: 1.0
is: SBO:0000247
has only substance units: false
initial amount: NaN
type: Species
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_67be90bf_3897_4a49_bd62_bd75f85dc83b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5bc5adf9_4463_468e_927b_1cb7731dad03
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2d4a8b7d_6b50_44fa_a87e_4bb0ba27981c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0f675474_e206_4541_951e_b91a420ffee9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9eaf18fe_59ef_444d_94d9_33d4954c4f8a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5021b4e6_f9d5_4e6a_b909_db50bca578c6
has only substance units: false
is encoded by: hsa:1717
is: SBO:0000252
boundary condition: true
constant: false
is: Q9UBM7
name: DHCR7
type: Species
initial amount: NaN
notes: DRUGBANK_UNKNOWN: DB00157
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#e70a66f0_5f21_4721_9d52_7d279d8072e7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b1e898a5_bbed_4f7e_8c8c_835161341a35
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1852
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
type: Reaction
is described by: http://identifiers.org/pubmed/14770310
name: Y+LAT2 Utilized transport
reactant: MODEL1109130000#
product: MODEL1109130000#
modifier: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/14770309
fast: false
is: SBO:0000185

metaR DURIPP
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/6087295
is described by: http://identifiers.org/pubmed/11278417
modifier: MODEL1109130000#
name: deoxyuridine phosphorylase
is version of: ECO:0000269
type: Reaction
is described by: http://identifiers.org/pubmed/9305963
product: MODEL1109130000#
is: SBO:0000176
notes: GENE_ASSOCIATION: (4860.1) or (151531.1) SUBSYSTEM: Nucleotide interconversion EC Number: Confidence Level: 4 AUTHORS: PMID:11278417,PMID:12849978,PMID:6087295,PMID:9305963 NOTES: JLR
is described by: http://identifiers.org/pubmed/12849978
reversible: true
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_1e7c4236_fe92_405c_95ab_42197894006d
value: 1000.0
type: LocalParameter

metaM gthrd x
boundary condition: false
is: CHEBI:57925
constant: false
has only substance units: false
is: HMDB00125
initial concentration: 1.0
name: glutathionate(1-)
initial amount: NaN
is: SBO:0000247
notes: FORMULA: C10H16N3O6S CHARGE: -1 INCHI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/p-1/t5-,6-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00056 EHMN_ABBREVIATION: C00051
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_4e107e2e_e63f_4a47_822b_6ee9e28c05cb
value: 0.0
type: LocalParameter

metaR r2122
modifier: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
reactant: MODEL1109130000#
is: SBO:0000185
reversible: true
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6f3949a7_c006_4227_8400_0b6b39ecd3a1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7a6b8b7f_1f68_43a7_bddb_4425d9ebc05a
boundary condition: true
is: P13929
constant: false
type: Species
initial amount: NaN
is: SBO:0000252
name: ENO3
is encoded by: hsa:2027
initial concentration: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#d78f2801_0e26_4d16_a318_7d81f49d2583
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3cdb623b_b9f1_40a7_a6ce_f9c15ed8ce4c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f10a6901_50a7_4c4f_a1b8_015a26bd83f8
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a448d9c4_fe31_4e36_b46f_9987a8291528
value: -1000.0
type: LocalParameter

metaR r2121
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
modifier: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
fast: false
reversible: true
product: MODEL1109130000#
is: SBO:0000185
type: Reaction

metaM hmgcoa c
initial concentration: 1.0
is: SBO:0000247
is: HMDB01375
initial amount: NaN
boundary condition: false
is: CHEBI:15467
notes: FORMULA: C27H39N7O20P3S CHARGE: -5 INCHI: InChI=1S/C27H44N7O20P3S/c1-26(2,21(40)24(41)30-5-4-15(35)29-6-7-58-17(38)9-27(3,42)8-16(36)37)11-51-57(48,49)54-56(46,47)50-10-14-20(53-55(43,44)45)19(39)25(52-14)34-13-33-18-22(28)31-12-32-23(18)34/h12-14,19-21,25,39-40,42H,4-11H2,1-3H3,(H,29,35)(H,30,41)(H,36,37)(H,46,47)(H,48,49)(H2,28,31,32)(H2,43,44,45)/p-5/t14-,19-,20-,21+,25-,27+/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00302 EHMN_ABBREVIATION: C00356
has only substance units: false
name: Hydroxymethylglutaryl-CoA
constant: false
type: Species

metaR C14STRr
type: Reaction
reversible: false
fast: false
is version of: ECO:0000134
is described by: http://identifiers.org/pubmed/16784888
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 7108.1 SUBSYSTEM: Cholesterol metabolism EC Number: 1.3.1.70 Confidence Level: 4 AUTHORS: PMID:16784888 NOTES: NCD ER version NJ
product: MODEL1109130000#
name: C-14 sterol reductase
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.3.1.70
is: SBO:0000176

metaM C14768 c
initial concentration: 1.0
notes: FORMULA: C20H31O3 CHARGE: -1 INCHI: InChI=1/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-10,12-13,18-19H,2-5,8,11,14-17H2,1H3,(H,21,22)/b7-6-,10-9-,13-12- EHMN_ABBREVIATION: C14768
is: HMDB02190
initial amount: NaN
name: 5,6-EET
boundary condition: false
is: C14768
has only substance units: false
constant: false
is: SBO:0000247
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_966f07a9_53a8_4055_b1fe_f2fa1f27be62
initial concentration: NaN
initial amount: NaN
constant: true
is: B0QY72
is encoded by: hsa:27349
is: SBO:0000252
boundary condition: true
name: MCAT
has only substance units: false
type: Species

metaR CRTSLtm
reactant: MODEL1109130000#
is: SBO:0000185
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 1 AUTHORS: NOTES: unknown mechanism NJ
is version of: ECO:0000000
fast: false
name: cortisol intracellular transport
type: Reaction
product: MODEL1109130000#
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#bb1fe76c_1e9c_4c01_b17a_66a85ef06837
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2484cbd7_cc7f_4ccf_898f_4b288986459f
value: 1000.0
type: LocalParameter

metaR RE3227R
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10970790
is: SBO:0000176
product: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction
name: RE3227
notes: GENE_ASSOCIATION: 64834.1 SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
reversible: true

metaR r2124
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
fast: false
is: SBO:0000185
reversible: true
reactant: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
product: MODEL1109130000#
type: Reaction

metaM cmpntm2amep c
boundary condition: false
notes: FORMULA: C14H25N4O10P2 CHARGE: -1 INCHI: InChI=1/C14H26N4O10P2/c1-18(2,3)6-7-29(22,23)28-30(24,25)26-8-9-11(19)12(20)13(27-9)17-5-4-10(15)16-14(17)21/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25)/p+1/t9-,11-,12-,13-/m1/s1 EHMN_ABBREVIATION: C05674
initial amount: NaN
name: CMP-N-trimethyl-2-aminoethylphosphonate
is: SBO:0000247
is: http://identifiers.org/pubchem.substance/7981
is: C05674
initial concentration: 1.0
constant: false
has only substance units: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_bcceef14_d14a_4f74_ac46_a0916a59dbdf
boundary condition: true
name: AADAC
initial amount: NaN
initial concentration: NaN
type: Species
is: P22760
constant: true
is: SBO:0000252
has only substance units: false
is encoded by: hsa:13

http://identifiers.org/biomodels.db/MODEL1109130000#_5e425513_c957_4df3_83a8_e0ef16c720c7
value: 0.0
type: LocalParameter

metaM CN0017 c
constant: false
is: SBO:0000247
has only substance units: false
initial concentration: 1.0
initial amount: NaN
boundary condition: false
notes: FORMULA: CHARGE: 0 EHMN_ABBREVIATION: CN0017 INCHI:
type: Species
name: Dibenzo[a,l]pyrene-11,12-epoxide

http://identifiers.org/biomodels.db/MODEL1109130000#_0c5e461e_c07c_4c87_b014_fb40d5eb8958
initial amount: NaN
name: SLC5A10
is: SBO:0000252
type: Species
has only substance units: false
constant: false
initial concentration: NaN
is encoded by: hsa:125206
boundary condition: true
is: A0PJK1

http://identifiers.org/biomodels.db/MODEL1109130000#_0b62b87b_13a3_44ee_814f_a96ba65f976d
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b2a371e5_310c_46f5_940b_0fc1d79675c4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4976875d_3e9d_4cbd_8314_7b59524db30f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fde9bc9e_310e_4033_a67e_d6af8f1ab7ad
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_171e7bd7_7694_4177_b588_2cce0dfb380c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4ff65a34_f0f9_425e_8f35_6048ac450ab5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cc001514_0e00_4bf2_8d33_4cd92afb7ad8
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b35276f5_4b8d_4f65_b55f_9d1d836baff9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a203016_c565_4c4f_8d0d_c4b9193af396
name: CPT1C
type: Species
initial concentration: NaN
is encoded by: hsa:126129
has only substance units: false
initial amount: NaN
constant: true
is: SBO:0000252
is: Q8TCG5
boundary condition: true

metaR r2123
is described by: http://identifiers.org/pubmed/12739169
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
fast: false
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
reversible: true
product: MODEL1109130000#
is: SBO:0000185
type: Reaction
reactant: MODEL1109130000#

metaR RE1050L
fast: false
notes: GENE_ASSOCIATION: (4353.1) or (9588.1) SUBSYSTEM: Miscellaneous EC Number: 1.11.1.7 Confidence Level: 0 AUTHORS: PMID:11013238 NOTES:
name: RE1050
is described by: http://identifiers.org/pubmed/11013238
type: Reaction
product: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000176
reversible: true
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.11.1.7

http://identifiers.org/biomodels.db/MODEL1109130000#_531ee26c_2c3d_4a10_bd2b_111e9ec5fba0
value: 1000.0
type: LocalParameter

metaM CE7090 n
constant: false
name: 18R-HEPE
boundary condition: false
type: Species
initial concentration: 1.0
notes: FORMULA: C20H29O3 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE7090
initial amount: NaN
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_9023681a_14b9_4fd4_b9ff_498b34022a0a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_77cb5d74_ffca_4d9b_9654_c6d6a4a5ea8b
value: 0.0
type: LocalParameter

metaR RE1050E
notes: GENE_ASSOCIATION: 4025.1 SUBSYSTEM: Miscellaneous EC Number: 1.11.1.7 Confidence Level: 0 AUTHORS: PMID:11013238 NOTES:
type: Reaction
is version of: http://identifiers.org/ec-code/1.11.1.7
is described by: http://identifiers.org/pubmed/11013238
modifier: MODEL1109130000#
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
reversible: true
name: RE1050
is: SBO:0000176

metaR EX aprgstrn LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: 20alpha-Hydroxyprogesterone exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_7c211c34_c793_4b4b_9bfa_cdaf7049d79d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6af714d4_0d1c_4d18_8dee_5197b0e60237
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9026196f_9844_401e_a757_4d82ce5f301b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8e9871e_b9d5_4564_88cb_1c76260254eb
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f306bbe3_322d_4e28_a765_d9f1d792b29f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1dbad4e0_3b1a_4970_aab7_f57699098e70
value: 1000.0
type: LocalParameter

metaM s2l2fn2m2masn l
has only substance units: false
constant: false
initial concentration: 1.0
type: Species
boundary condition: false
is: SBO:0000247
notes: FORMULA: C90H145N6O65X CHARGE: -2 INCHI:
name: PA6
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#f0413bd7_fbc7_43b3_8188_43ea59cb4e3d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_056f4eda_b605_4c78_a1cc_171a2b97511b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_899c0ad7_31ea_4b60_baca_db1555ffb67d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c1339b32_9419_4ba2_a191_d2e183086731
value: 1000.0
type: LocalParameter

metaM CE2881 c
boundary condition: false
type: Species
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C14H7I4O4 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE2881
initial amount: NaN
name: 3,5,3,5-tetraiodothyroacetate
has only substance units: false
constant: false

metaM dmgly c
is: SBO:0000247
is: HMDB00092
type: Species
initial concentration: 1.0
boundary condition: false
constant: false
is: CHEBI:17724
name: N,N-dimethylglycine
has only substance units: false
notes: FORMULA: C4H9NO2 CHARGE: 0 INCHI: InChI=1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7) EHMN_ABBREVIATION: C01026
initial amount: NaN

metaM CE0074 c
is: HMDB02818
name: alloxan
initial amount: NaN
is: SBO:0000247
has only substance units: false
notes: FORMULA: C4H2N2O4 CHARGE: 0 INCHI: InChI=1/C4H2N2O4/c7-1-2(8)5-4(10)6-3(1)9/h(H2,5,6,8,9,10) EHMN_ABBREVIATION: CE0074
boundary condition: false
initial concentration: 1.0
constant: false
type: Species

metaM anth c
boundary condition: false
has only substance units: false
name: anthranilate
is: CHEBI:16567
is: HMDB01123
initial amount: NaN
is: SBO:0000247
constant: false
notes: FORMULA: C7H6NO2 CHARGE: -1 INCHI: InChI=1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)/p-1 HEPATONET_1.0_ABBREVIATION: HC00107 EHMN_ABBREVIATION: C00108
type: Species
initial concentration: 1.0

metaM 56dihindlcrbxlt c
initial concentration: 1.0
name: 5,6-dihydroxyindole-2-carboxylate
type: Species
notes: FORMULA: C9H6NO4 CHARGE: -1 INCHI: InChI=1S/C9H7NO4/c11-7-2-4-1-6(9(13)14)10-5(4)3-8(7)12/h1-3,10-12H,(H,13,14)/p-1 EHMN_ABBREVIATION: C04185
has only substance units: false
constant: false
is: SBO:0000247
is: HMDB01253
is: CHEBI:16875
boundary condition: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#d7aefa2b_0194_4b9a_b147_a9fa440b1667
value: 1000.0
type: LocalParameter

metaR r2120
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
reactant: MODEL1109130000#
is: SBO:0000185
reversible: true
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
modifier: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
type: Reaction
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_1c1b7e50_1ccf_4b97_ad03_9515ac39b49b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e383b7e6_97b5_461e_bd99_8a97ef6ebe21
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_46bffb54_07e0_4794_b0a7_d9c74e0a73d2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ce6c645f_e897_48cc_965a_80957db2003e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2ec3b17b_e2fa_41f6_a199_241fe1540926
constant: false
is: SBO:0000252
name: MCCC2
initial amount: NaN
initial concentration: NaN
has only substance units: false
boundary condition: true
is: Q9HCC0
type: Species
notes: DRUGBANK_UNKNOWN: DB00121
is encoded by: hsa:64087

metaM carveol c
is: SBO:0000247
type: Species
constant: false
initial amount: NaN
boundary condition: false
initial concentration: 1.0
is: HMDB03450
notes: FORMULA: C10H16O CHARGE: 0 INCHI: InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3/t9-,10+/m1/s1 EHMN_ABBREVIATION: C00964
is: CHEBI:15389
has only substance units: false
name: (-)-trans-carveol

http://identifiers.org/biomodels.db/MODEL1109130000#bc08ca70_fba8_4579_8529_8aa8d57a8239
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_263b4f9b_b6c0_44df_95b7_d4c2232595a6
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_01197b49_9229_4ae0_a1f1_856cf46cdf99
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_870fdca6_70df_4998_8b1f_e7d7485bdacf
value: 0.0
type: LocalParameter

metaM CE6185 m
initial concentration: 1.0
notes: FORMULA: C18H24O6 CHARGE: -2 INCHI: InChI=1/C18H26O6/c19-15(11-6-3-7-13-17(21)22)9-4-1-2-5-10-16(20)12-8-14-18(23)24/h1-6,9-10,15-16,19-20H,7-8,11-14H2,(H,21,22)(H,23,24)/p-2/b2-1+,6-3-,9-4+,10-5-/t15-,16+/m1/s1 EHMN_ABBREVIATION: CE6185
boundary condition: false
initial amount: NaN
constant: false
is: SBO:0000247
has only substance units: false
type: Species
name: omega-carboxy-trinor-leukotriene B4

http://identifiers.org/biomodels.db/MODEL1109130000#_6f39f919_1dcd_4f94_8a0a_d9ad25986693
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5fbc4c98_8fc0_4877_ba30_16c44530b012
value: -1000.0
type: LocalParameter

metaR EX g1p LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Exchange of alpha-D-glucose 1-phosphate(2-)
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#bcf12ebb_39c1_49ba_b44f_21fe79ce4f04
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_02cff7a0_f444_4b66_b6d3_762a6c9378a9
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_25a13694_c829_4c24_8ddd_07518bf0dc34
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_13c414b8_8c03_4836_9720_4b2060155c2d
value: 1000.0
type: LocalParameter

metaR CRTSLtr
name: cortisol intracellular transport
is: SBO:0000185
fast: false
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 1 AUTHORS: NOTES: unknown mechanism NJ
type: Reaction
is version of: ECO:0000000
product: MODEL1109130000#
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_7b9e1e59_cd1e_4b17_b92c_2694ab0882c5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_f99fe63b_c3bb_45a1_bda3_38d1e450b24c
has only substance units: false
is: SBO:0000252
boundary condition: true
initial amount: NaN
is: P30613
type: Species
is encoded by: hsa:5313
name: PKLR
initial concentration: NaN
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_389878b8_d6f9_45b7_a803_fbf830d7c285
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE0923C
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:7263841 NOTES:
name: RE0923
is version of: http://identifiers.org/ec-code/2.4.1.17
fast: false
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7263841
type: Reaction
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: false

metaM anth e
notes: FORMULA: C7H6NO2 CHARGE: -1 INCHI: InChI=1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)/p-1
constant: false
type: Species
initial amount: NaN
name: anthranilate
is: HMDB01123
boundary condition: false
has only substance units: false
is: CHEBI:16567
is: SBO:0000247
initial concentration: 1.0

metaM CE0074 e
is: HMDB02818
initial amount: NaN
is: SBO:0000247
name: alloxan
constant: false
boundary condition: false
initial concentration: 1.0
type: Species
has only substance units: false
notes: FORMULA: C4H2N2O4 CHARGE: 0 INCHI: InChI=1/C4H2N2O4/c7-1-2(8)5-4(10)6-3(1)9/h(H2,5,6,8,9,10) EHMN_ABBREVIATION: CE0074

http://identifiers.org/biomodels.db/MODEL1109130000#e5a75b2a_cbe5_4a7a_b9df_b78e4daf62f7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f1bf15c1_bcb7_4096_a177_41bd5d61066e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2158d90b_4d00_4f2d_be6a_2b4df92eabb4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_23e45ddf_8586_446e_91ec_f3177d46879c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8639cd3b_db2a_4196_9065_b1e23f29ce9e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_eb3eac89_01bd_41b2_894f_d7bc746f404e
is: SBO:0000252
constant: true
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:5051
is: Q99487
name: PAFAH2
type: Species
boundary condition: true
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#e9c9fa7f_c3c7_484b_a37c_f8db75761e29
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0e7a8a55_ac24_4330_b900_8eeb2f154986
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dde57359_e54e_485a_aeb6_81afb4368f0a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_130e0fd2_2bf7_4217_9619_f0c1a56593d5
name: CHAT
type: Species
constant: false
is: SBO:0000252
is encoded by: hsa:1103
is: D3DX95
initial amount: NaN
boundary condition: true
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_374c3a9a_c1d5_43e5_a6c3_513cddab5b78
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_03dc1747_8ebb_407b_b150_58bcaf64f04b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_95ba21d9_1776_4a91_8ccd_24825984ec3c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f2357cb8_841e_4e65_bcba_704ac6f10566
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_44af6d0e_7e0e_4cb4_a34e_946ae0843c6e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_357fbc3c_ba83_4780_99f3_d42383c8ec16
type: Species
initial amount: NaN
initial concentration: NaN
is encoded by: hsa:54682
is: Q9H8J5
boundary condition: true
constant: true
name: MANSC1
has only substance units: false
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_cf61d155_2cd9_4eb7_ab6a_09c78692f653
is: P07686
boundary condition: true
is encoded by: hsa:3074
constant: true
type: Species
is: SBO:0000252
initial concentration: NaN
name: HEXB
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#a287e8ce_cf6f_45cd_aa2e_d387045d662d
value: -1000.0
type: LocalParameter

metaR MMTSADm
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
is version of: ECO:0000000
reversible: false
is described by: http://identifiers.org/pubmed/1527093
fast: false
name: malonate-semialdehyde dehydrogenase (acetylating), mitochondrial
notes: GENE_ASSOCIATION: SUBSYSTEM: Valine, leucine, and isoleucine metabolism EC Number: Confidence Level: 2 AUTHORS: PMID:1527093 NOTES: MM. biochemical activity measured in rat, sequence similarity found in human
is: SBO:0000176

metaR DHORD9
fast: false
is version of: http://identifiers.org/ec-code/1.3.3.1
is described by: http://identifiers.org/pubmed/9693067
is: SBO:0000185
reversible: false
product: MODEL1109130000#
modifier: MODEL1109130000#
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/10727948
type: Reaction
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 1723.1 SUBSYSTEM: Pyrimidine synthesis EC Number: 1.3.3.1 Confidence Level: 4 AUTHORS: PMID:10727948,PMID:9693067 NOTES: _06-15-05 - EC 1.3.3.1 IT based on Bader et al, 1998, Prot. Expr. Purif,., 13,414-422 (I guess it is ubiquinone but i am not sure ) (needs FMN as cofactor) v(enzyme is located in inner-membrane of mitochondria, reaction take place in cytosol (Fig. 8 Rawls et al PMID: 10727948 )
name: dihydoorotic acid dehydrogenase (quinone10)

http://identifiers.org/biomodels.db/MODEL1109130000#_2b0506c2_e614_441f_a153_432f023a313c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c9dd129e_b796_4a3c_b4b9_d9ef8387b34f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_529b27ec_4f82_4fdb_b183_8a03f74cca88
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_259fbcd6_3a4e_42c8_a2af_b109415d4326
value: 0.0
type: LocalParameter

metaR 41R2A1H12BOOX
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8920635
name: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9653080
fast: false
is version of: http://identifiers.org/ec-code/1.4.3.4
is: SBO:0000176
is version of: ECO:0000269
notes: GENE_ASSOCIATION: (4128.1) or (4129.1) SUBSYSTEM: Tyrosine metabolism EC Number: 1.4.3.4 Confidence Level: 4 AUTHORS: PMID:15035803,PMID:8920635,PMID:9653080 NOTES: SAB
modifier: MODEL1109130000#
type: Reaction
reversible: false
is described by: http://identifiers.org/pubmed/15035803

metaM carveol e
name: (-)-trans-carveol
has only substance units: false
boundary condition: false
is: CHEBI:15389
type: Species
notes: FORMULA: C10H16O CHARGE: 0 INCHI: InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3/t9-,10+/m1/s1 EHMN_ABBREVIATION: C00964
is: SBO:0000247
constant: false
initial amount: NaN
initial concentration: 1.0
is: HMDB03450

http://identifiers.org/biomodels.db/MODEL1109130000#_9a2f7de4_1460_4c10_b73f_3d7b3dace69a
has only substance units: false
is: Q9Y619
name: SLC25A15
boundary condition: true
is: SBO:0000252
constant: true
is encoded by: hsa:10166
notes: DRUGBANK_UNKNOWN: DB00129
type: Species
initial amount: NaN
initial concentration: NaN

metaM L2aadp c
type: Species
name: L-2-aminoadipate(1-)
initial concentration: 1.0
initial amount: NaN
is: CHEBI:58672
boundary condition: false
has only substance units: false
is: HMDB00510
is: SBO:0000247
notes: FORMULA: C6H10NO4 CHARGE: -1 INCHI: InChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/p-1/t4-/m0/s1 HEPATONET_1.0_ABBREVIATION: HC00599 EHMN_ABBREVIATION: C00956
constant: false

metaM CE2949 c
boundary condition: false
notes: FORMULA: C10H5NO4 CHARGE: -2 INCHI: InChI=1/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-3,12H,4H2,(H,14,15)/p-1 EHMN_ABBREVIATION: CE2949
is: SBO:0000247
name: oxoxanthurenate
initial concentration: 1.0
constant: false
initial amount: NaN
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_c7bcd4af_7cd3_4cbb_b313_43cf8e24c9a1
initial amount: NaN
has only substance units: false
is encoded by: hsa:29926
boundary condition: true
constant: true
is: SBO:0000252
type: Species
name: GMPPA
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#a4ec2229_ed54_4332_ab4f_385788f7242a
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE1937 c
is: SBO:0000247
name: spermic acid 1
has only substance units: false
boundary condition: false
constant: false
notes: FORMULA: C10H25N3O2 CHARGE: 2 INCHI: InChI=1/C10H23N3O2/c11-5-3-8-12-6-1-2-7-13-9-4-10(14)15/h12-13H,1-9,11H2,(H,14,15)/p+2 EHMN_ABBREVIATION: CE1937
initial amount: NaN
initial concentration: 1.0
type: Species

metaR KSII CORE2t
name: keratan sulfate II (core2) transport, golgi to extracellular
reactant: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
is: SBO:0000185
reversible: false
is version of: ECO:0000000
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES:

metaR G14T13g
type: Reaction
is described by: http://identifiers.org/pubmed/1903938
is described by: http://identifiers.org/pubmed/3094506
reactant: MODEL1109130000#
fast: false
reversible: false
name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi
notes: GENE_ASSOCIATION: (8703.1) or (2683.1) or (8704.2) or (8704.1) or (9334.1) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.1.38 Confidence Level: 4 AUTHORS: PMID:12512857,PMID:1903938,PMID:3094506,PMID:3144273,PMID:9405390,PMID:9435216 NOTES: Keratan sulfate I biosynthesis NCD
is described by: http://identifiers.org/pubmed/3144273
is version of: ECO:0000000
is version of: http://identifiers.org/ec-code/2.4.1.38
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9435216
is described by: http://identifiers.org/pubmed/9405390
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/12512857

http://identifiers.org/biomodels.db/MODEL1109130000#c9c2b110_461c_421b_a2b7_cd14dc54ceb1
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8f0afbd2_3e89_41af_870b_3dd15ba5cce5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f1df7a5c_26a8_4447_bc4b_d1418140f303
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_85c90703_e6cb_461f_8134_5b8cc524a028
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3131d3b0_8de6_4397_a389_29f0f33adf2b
initial amount: NaN
initial concentration: NaN
boundary condition: true
is encoded by: hsa:132158
is: SBO:0000252
has only substance units: false
is: Q8IVS8
constant: false
name: GLYCTK
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#e1707547_fa83_4746_8d22_dbda3f35dade
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e70f6604_8552_4c44_aac6_f2f4a9c281a9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6dfda35d_e0a7_4f71_a23a_460390314937
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b3fdd993_6870_4469_a682_362acc06016a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2489fafd_4c56_424d_9974_e7e9efe36fc7
value: 0.0
type: LocalParameter

metaM CE0074 n
notes: FORMULA: C4H2N2O4 CHARGE: 0 INCHI: InChI=1/C4H2N2O4/c7-1-2(8)5-4(10)6-3(1)9/h(H2,5,6,8,9,10) EHMN_ABBREVIATION: CE0074
initial amount: NaN
boundary condition: false
type: Species
constant: false
name: alloxan
is: SBO:0000247
has only substance units: false
is: HMDB02818
initial concentration: 1.0

metaR r2139
type: Reaction
reversible: true
product: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/11076394
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
is: SBO:0000185
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_456affb5_2c5d_4c78_be2c_9ce4574f1918
value: 1000.0
type: LocalParameter

metaR RE1956X
type: Reaction
reactant: MODEL1109130000#
fast: false
is: SBO:0000176
modifier: MODEL1109130000#
name: RE1956
is described by: http://identifiers.org/pubmed/11323741
is version of: http://identifiers.org/ec-code/3.3.2.9
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9870464
notes: GENE_ASSOCIATION: 2053.1 SUBSYSTEM: Arachidonic acid metabolism EC Number: 3.3.2.9 Confidence Level: 0 AUTHORS: PMID:11323741,PMID:9870464 NOTES:
reversible: true

metaR EX glcur LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: D-glucuronate exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#f3968f6e_007f_46ea_9682_908b091275dd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5d7c3f40_9359_487b_a1ef_1970f59151b5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e6cf512b_0a92_4477_9fba_922d9ffc8a31
units: dimensionless
value: 0.0
type: LocalParameter

metaR PEFLIP
fast: false
is version of: http://identifiers.org/ec-code/3.6.3.1
is described by: http://identifiers.org/pubmed/11353404
is described by: http://identifiers.org/pubmed/10198212
is version of: ECO:0000269
type: Reaction
notes: GENE_ASSOCIATION: (10396.1) or (57194.1) SUBSYSTEM: Transport, extracellular EC Number: 3.6.3.1 Confidence Level: 4 AUTHORS: PMID:10198212,PMID:10856717,PMID:11353404 NOTES: See PMID: 10856717 - flippase activity NJ
name: phosphatidylethanolamine flippase
product: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10856717
reactant: MODEL1109130000#
is: SBO:0000185
reversible: false

http://identifiers.org/biomodels.db/MODEL1109130000#_45b95821_9209_4763_85f5_d9968707e0c3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7818af59_cfaf_440f_b7c3_65def24caaee
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cc8f5055_7bcb_42d7_9d77_617706dc552a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_c9b3e8b3_5200_4713_8358_a8e6f5a66a89
is: SBO:0000252
initial amount: NaN
is encoded by: hsa:55361
type: Species
constant: false
is: Q9BTU6
name: PI4K2A
boundary condition: true
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#e95fa8de_f0b7_43b1_89be_7fb573820cc7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9555e023_cd7c_402a_8bda_521c6080a76d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b890c721_8146_4085_9417_9776be851a81
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e1a51988_5499_4a2a_b092_71822ca15fe9
value: -1000.0
type: LocalParameter

metaR RE1050N
modifier: MODEL1109130000#
reactant: MODEL1109130000#
name: RE1050
is described by: http://identifiers.org/pubmed/11013238
is version of: http://identifiers.org/ec-code/1.11.1.7
type: Reaction
product: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: 4353.1 SUBSYSTEM: Miscellaneous EC Number: 1.11.1.7 Confidence Level: 0 AUTHORS: PMID:11013238 NOTES:
fast: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_1d94f6e2_a49c_413e_9cf9_9472f6735b7d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_46b86efb_a2ac_4752_8c5f_e1cf1141f679
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_97ed52fe_3907_4f4c_85d8_0c966ce83695
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGF:PIGO
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#f88b0b52_d0a6_4f20_8fcf_39ff77a9368f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_28faed2d_f35b_4584_9413_223df58dbd69
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#abcd19d0_a169_4c16_a479_fa4ac591027e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9242b218_e53f_41bc_8210_b3b2113551d1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0f3418d3_56b7_4abf_9d9f_b49c80702017
has only substance units: false
is: P30041
boundary condition: true
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:9588
constant: true
type: Species
is: SBO:0000252
name: PRDX6

http://identifiers.org/biomodels.db/MODEL1109130000#_3f79d396_420e_4a28_8bf7_1fa098148442
value: 0.0
type: LocalParameter

metaR PHEACGLNt
name: PHEACGLN extracellular transport via diffusion
is: SBO:0000185
is described by: http://identifiers.org/pubmed/14681857
product: MODEL1109130000#
type: Reaction
fast: false
is version of: ECO:0000000
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14681857 NOTES: SAB
reactant: MODEL1109130000#

metaR r2137
name: Major Facilitator(MFS) TCDB:2.A.1.14.6
modifier: MODEL1109130000#
product: MODEL1109130000#
is: SBO:0000185
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12811560 NOTES:
reversible: true
is described by: http://identifiers.org/pubmed/12811560
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_94e1ca1f_1219_4a7a_87a4_8f41c11b576a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_28f6b835_4d82_453d_b4e8_ebfe8bab3731
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a880d0f5_844a_40ad_912c_2c0356e79640
value: 0.0
type: LocalParameter

metaR RE3066X
is: SBO:0000176
reversible: false
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.14.11.18
notes: GENE_ASSOCIATION: 5264.1 SUBSYSTEM: Fatty acid oxidation EC Number: 1.14.11.18 Confidence Level: 0 AUTHORS: PMID:8954107 NOTES:
fast: false
reactant: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/8954107
name: RE3066
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_8d3e904a_3315_4ed6_b890_90aedd0a5176
value: 0.0
type: LocalParameter

metaR PYRt2m
reversible: true
is described by: http://identifiers.org/pubmed/6987111
notes: GENE_ASSOCIATION: 6566.1 SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 0 AUTHORS: PMID:14598172,PMID:6987111 NOTES: IF changed name from "tm" to "t2m" - NCD
product: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/14598172
name: pyruvate mitochondrial transport via proton symport
type: Reaction
reactant: MODEL1109130000#
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_7202a63c_4eef_4c9d_8207_5dd51f67a7da
value: 0.0
type: LocalParameter

metaM CE6185 c
name: omega-carboxy-trinor-leukotriene B4
type: Species
initial concentration: 1.0
constant: false
is: SBO:0000247
initial amount: NaN
notes: FORMULA: C18H24O6 CHARGE: -2 INCHI: InChI=1/C18H26O6/c19-15(11-6-3-7-13-17(21)22)9-4-1-2-5-10-16(20)12-8-14-18(23)24/h1-6,9-10,15-16,19-20H,7-8,11-14H2,(H,21,22)(H,23,24)/p-2/b2-1+,6-3-,9-4+,10-5-/t15-,16+/m1/s1 EHMN_ABBREVIATION: CE6185
has only substance units: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6826f1ed_ee79_47b3_8410_ec0c5dfce6c4
value: -1000.0
type: LocalParameter

metaM CE1310 m
initial amount: NaN
boundary condition: false
initial concentration: 1.0
is: SBO:0000247
type: Species
has only substance units: false
constant: false
notes: FORMULA: C5H8NO3S CHARGE: -1 INCHI: InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1 EHMN_ABBREVIATION: CE1310
is: CHEBI:28939
name: N-acetyl-L-cysteine

http://identifiers.org/biomodels.db/MODEL1109130000#_6834c279_2454_46ef_bad2_f227c708ac43
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7890b5e3_cf83_4650_bad1_f9fb17e0e9b3
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE3228R
is: SBO:0000176
reversible: true
reactant: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/10970790
notes: GENE_ASSOCIATION: 64834.1 SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
name: RE3228
modifier: MODEL1109130000#
type: Reaction
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_4b9059e4_3aab_417a_bf41_525275d463b7
type: Species
is: Q6TCH8
is: SBO:0000252
is encoded by: hsa:10873
has only substance units: false
boundary condition: true
initial amount: NaN
name: ME3
initial concentration: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3e45d9cf_8034_4281_9f3c_6a7b9ce28557
constant: false
is: Q59EA4
is: SBO:0000252
initial concentration: NaN
name: PLD1
has only substance units: false
boundary condition: true
is encoded by: hsa:5337
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#a007247a_1183_4108_9d83_7f1a4a37d8fd
value: -1000.0
type: LocalParameter

metaM CE4834 r
notes: FORMULA: C45H68N7O18P3S CHARGE: -4 INCHI: InChI=1/C45H72N7O18P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-33(53)28-36(55)74-27-26-47-35(54)24-25-48-43(58)40(57)45(2,3)30-67-73(64,65)70-72(62,63)66-29-34-39(69-71(59,60)61)38(56)44(68-34)52-32-51-37-41(46)49-31-50-42(37)52/h8-9,11-12,14-15,17-18,31-32,34,38-40,44,56-57H,4-7,10,13,16,19-30H2,1-3H3,(H,47,54)(H,48,58)(H,62,63)(H,64,65)(H2,46,49,50)(H2,59,60,61)/p-4/b9-8-,12-11-,15-14-,18-17-/t34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4834
initial amount: NaN
has only substance units: false
initial concentration: 1.0
constant: false
boundary condition: false
name: 3-oxo-tetracosa-9,12,15,18-all-cis-tetraenoyl-CoA
type: Species
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_7c300ec0_d305_4a30_8454_ba6f84233a8c
value: 0.0
type: LocalParameter

metaR PYRt2p
reversible: true
modifier: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12739169
notes: GENE_ASSOCIATION: (6566.1) or (9194.1) SUBSYSTEM: D-alanine metabolism EC Number: Confidence Level: 4 AUTHORS: PMID:12705896,PMID:12739169,PMID:9786900 NOTES: NCD
type: Reaction
is described by: http://identifiers.org/pubmed/9786900
name: pyruvate peroxisomal transport via proton symport
is: SBO:0000185
is described by: http://identifiers.org/pubmed/12705896
is version of: ECO:0000269

http://identifiers.org/biomodels.db/MODEL1109130000#a140aa37_6989_4a59_bbd4_fe548f670f65
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a3441b6e_b0a8_4622_be58_07a11ea6b9d4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f28836a8_74e9_4433_ab1a_2dfebad6d4eb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1a08c162_5668_43a7_8f39_4f4f6d13889d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_05f359ac_d776_43d1_a0a7_4a071571567e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a0a026e_463a_4b9d_8ef8_ff1108066407
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_93b43111_a473_4b21_9c54_2b14c6506f5c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8d057c04_b26e_428a_a0b7_2a85f6406aab
name: GK3P
type: Species
has only substance units: false
constant: true
is: SBO:0000252
initial concentration: NaN
is encoded by: hsa:2713
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_7d6a32a7_6a60_4828_9dd7_56a70e26f716
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_21751d33_f620_422d_b803_173a14ef1449
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f8a16d35_8e02_47a4_a26c_f0e56c52c955
value: 1000.0
type: LocalParameter

metaR RE3228C
product: MODEL1109130000#
name: RE3228
type: Reaction
reversible: true
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
is described by: http://identifiers.org/pubmed/10970790
reactant: MODEL1109130000#
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_1194c069_34b9_473b_87b7_383bbaff6b46
value: 0.0
type: LocalParameter

metaM CE0737 c
name: malonic dialdehyde
has only substance units: false
is: HMDB06112
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C3H3O2 CHARGE: -1 INCHI: InChI=1/C3H4O2/c4-2-1-3-5/h2-3H,1H2 EHMN_ABBREVIATION: CE0737
boundary condition: false
initial amount: NaN
constant: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_2892dbf4_3738_4bc6_9059_ff4771e3a7be
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_665ab452_d0bd_4984_a983_39c0d9da0d69
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7d4a4c26_2312_4014_af12_74d9e865777c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b2785a47_e1a7_419b_96b5_8125d14d20c7
value: 0.0
type: LocalParameter

metaR RE1956R
product: MODEL1109130000#
name: RE1956
is described by: http://identifiers.org/pubmed/11323741
reactant: MODEL1109130000#
type: Reaction
fast: false
reversible: true
is: SBO:0000176
notes: GENE_ASSOCIATION: 2052.1 SUBSYSTEM: Arachidonic acid metabolism EC Number: 3.3.2.9 Confidence Level: 0 AUTHORS: PMID:11323741,PMID:9870464 NOTES:
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.3.2.9
is described by: http://identifiers.org/pubmed/9870464

http://identifiers.org/biomodels.db/MODEL1109130000#_588b8278_bfd5_4bd9_af7f_fbfef2c9ad0c
units: dimensionless
value: 0.0
type: LocalParameter

metaR PSP L
is: SBO:0000176
type: Reaction
reactant: MODEL1109130000#
fast: false
name: phosphoserine phosphatase (L-serine)
is described by: http://identifiers.org/pubmed/9573387
is version of: http://identifiers.org/ec-code/3.1.3.3
is described by: http://identifiers.org/pubmed/9188776
reversible: false
notes: GENE_ASSOCIATION: (8781.1) or (5723.1) SUBSYSTEM: Glycine, serine, alanine and threonine metabolism EC Number: 3.1.3.3 Confidence Level: 4 AUTHORS: PMID:9188776,PMID:9573387 NOTES:
product: MODEL1109130000#
is version of: ECO:0000269
modifier: MODEL1109130000#

metaR r1850
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
reversible: false
modifier: MODEL1109130000#
name: Y+LAT2 Utilized transport
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
is: SBO:0000185
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_942df3e9_8b1e_47a2_a893_aa8bbcb29e54
value: 1000.0
type: LocalParameter

metaM nicrns c
boundary condition: false
is: HMDB06809
type: Species
initial amount: NaN
has only substance units: false
is: SBO:0000247
is: CHEBI:58527
notes: FORMULA: C11H13NO6 CHARGE: 0 HEPATONET_1.0_ABBREVIATION: HC01628 EHMN_ABBREVIATION: C05841 INCHI: InChI=1S/C11H13NO6/c13-5-7-8(14)9(15)10(18-7)12-3-1-2-6(4-12)11(16)17/h1-4,7-10,13-15H,5H2/t7-,8-,9-,10-/m1/s1
initial concentration: 1.0
name: Nicotinate D-ribonucleoside
constant: false

metaR RE2638X
fast: false
is version of: http://identifiers.org/ec-code/2.3.1.65
name: RE2638
notes: GENE_ASSOCIATION: 570.1 SUBSYSTEM: Bile acid synthesis EC Number: 2.3.1.65 Confidence Level: 0 AUTHORS: PMID:11980911 NOTES:
type: Reaction
is: SBO:0000176
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11980911
reactant: MODEL1109130000#
reversible: true
modifier: MODEL1109130000#

metaR PYRt2r
is described by: http://identifiers.org/pubmed/10510291
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/7835905
name: pyruvate reversible transport via proton symport
is described by: http://identifiers.org/pubmed/8476015
is described by: http://identifiers.org/pubmed/9824713
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9649795
is: SBO:0000185
type: Reaction
is described by: http://identifiers.org/pubmed/9786900
is described by: http://identifiers.org/pubmed/9425115
reversible: true
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (9123.1) or (9194.1) or (6566.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:10510291,PMID:11101640,PMID:12739169,PMID:7835905,PMID:8476015,PMID:9425115,PMID:9508842,PMID:9649795,PMID:9786900,PMID:9824713 NOTES: JLR
is described by: http://identifiers.org/pubmed/12739169
is described by: http://identifiers.org/pubmed/11101640
fast: false
is described by: http://identifiers.org/pubmed/9508842

metaM CE4793 r
initial concentration: 1.0
type: Species
name: 3-oxo-dihomo-gama-linolenoyl-CoA
is: SBO:0000247
boundary condition: false
has only substance units: false
constant: false
initial amount: NaN
notes: FORMULA: C41H62N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE4793

http://identifiers.org/biomodels.db/MODEL1109130000#_8a537c7f_f5d1_448b_89ed_56e4a676299e
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_16633350_9eac_4dcd_8a78_68e3f31705f5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_67966bd0_a807_4443_aebb_6edbba80f765
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_13ff61e5_f1c0_4c96_b208_ddfbd32a3f57
units: dimensionless
value: 0.0
type: LocalParameter

metaM agm m
initial amount: NaN
is: CHEBI:58145
notes: FORMULA: C5H16N4 CHARGE: 2 INCHI: InChI=1S/C5H14N4/c6-3-1-2-4-9-5(7)8/h1-4,6H2,(H4,7,8,9)/p+2 HEPATONET_1.0_ABBREVIATION: HC00171 EHMN_ABBREVIATION: C00179
name: agmatinium(2+)
constant: false
has only substance units: false
initial concentration: 1.0
is: SBO:0000247
is: HMDB01432
type: Species
boundary condition: false

metaM HC02021 r
constant: false
is: SBO:0000247
notes: FORMULA: CHARGE: 0
has only substance units: false
type: Species
name: Cholesterol-ester-palmn
initial amount: NaN
is: http://identifiers.org/pubchem.substance/24702202
boundary condition: false
initial concentration: 1.0

metaR DECCRNe
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 2 AUTHORS: Jones LL, McDonald DA, Borum PR. (2010). Progress in Lipid Research 49: 61-75 EC Number: NOTES: increased amounts in MCKAT and SCAD. GENE_ASSOCIATION:
is: SBO:0000185
fast: false
reversible: false
name: transport of 3-hydroxydecanoyl carnitine into extra cellular space
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_5b5fcadc_3717_4a0d_9f58_a24880aebada
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaR r1851
reversible: false
type: Reaction
modifier: MODEL1109130000#
is: SBO:0000185
reactant: MODEL1109130000#
name: Y+LAT2 Utilized transport
is described by: http://identifiers.org/pubmed/14770309
fast: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770310

http://identifiers.org/biomodels.db/MODEL1109130000#_268eb22e_40bd_4d00_948b_cebdb639875a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_33eceffa_ce22_44a2_b496_bcced75a1543
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5fa2aaf7_7660_4d62_af6a_b1104386ce73
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1d410610_dbc6_45ee_b278_5ab61850be69
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8720f3e3_a387_45fb_bca6_5f1227aea753
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d25a3161_b6ae_471f_a182_5983f40b7b30
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_62a7cc09_804d_4d98_9f80_e589fdf301e4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1c7cb89c_39da_4623_8392_82290bc66374
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f6cb00f9_e507_46a3_b6ef_fd28266568b0
value: 0.0
type: LocalParameter

metaR ENMAN4g
is: SBO:0000176
type: Reaction
reactant: MODEL1109130000#
name: Endomannosidase (m6masnC-producing), Golgi apparatus
is described by: http://identifiers.org/pubmed/11007802
reversible: false
product: MODEL1109130000#
is version of: ECO:0000000
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: N-glycan synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:11007802 NOTES: NCD

http://identifiers.org/biomodels.db/MODEL1109130000#_26c22a6b_21cc_4e62_a21a_e2eea1451176
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC00361 c
constant: false
notes: FORMULA: C7H12O13P2 CHARGE: -4 INCHI: InChI=1S/C7H16O13P2/c8-3(1-19-21(13,14)15)5(10)7(12)6(11)4(9)2-20-22(16,17)18/h3,5-8,10-12H,1-2H2,(H2,13,14,15)(H2,16,17,18)/p-4/t3-,5-,6-,7-/m1/s1 EHMN_ABBREVIATION: C00447
has only substance units: false
name: sedoheptulose 1,7-bisphosphate(4-)
is: CHEBI:58335
initial amount: NaN
type: Species
boundary condition: false
is: SBO:0000247
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_353f0ade_78e4_4489_9692_2c7ecde20e10
value: 1000.0
type: LocalParameter

metaM C05300 c
is: SBO:0000247
has only substance units: false
boundary condition: false
name: 16alpha-Hydroxyestrone
type: Species
is: CHEBI:776
initial amount: NaN
constant: false
is: HMDB00335
initial concentration: 1.0
notes: FORMULA: C18H22O3 CHARGE: 0 INCHI: InChI=1S/C18H22O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-16,19-20H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,18+/m1/s1 EHMN_ABBREVIATION: C05300

http://identifiers.org/biomodels.db/MODEL1109130000#_4d3c9ceb_26ec_4b06_9d34_510f0b20dd00
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_237007d6_8370_4e13_a92a_8bb8257b96b0
initial amount: NaN
has only substance units: false
is encoded by: hsa:4257
initial concentration: NaN
boundary condition: true
type: Species
constant: true
is: SBO:0000252
is: P10620
name: MGST1

http://identifiers.org/biomodels.db/MODEL1109130000#_01c97d94_7f99_4996_9d97_36a81fd22a8f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_87057991_bbd6_4280_aaf7_8d23dd10c2a9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_005df25c_3b1f_4e75_a575_1b7f1a1b587a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f5c685db_aeea_47c5_a7bc_9c7a975b003a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#abe5b80f_09cb_44ab_b155_aab5c9bab2a1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7436b3fd_3da5_4cb0_9b05_7f7ac0ddb886
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#edabadf1_d813_4f64_bcfb_5a88687fbbd6
value: -1000.0
type: LocalParameter

metaR DHAAt1r
type: Reaction
is described by: http://identifiers.org/pubmed/12750891
fast: false
is described by: http://identifiers.org/pubmed/9230074
is described by: http://identifiers.org/pubmed/3170580
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15705056
notes: GENE_ASSOCIATION: (6515.1) or (6513.1) or (6517.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:10421229,PMID:12750891,PMID:15705056,PMID:2656669,PMID:3170580,PMID:8504756,PMID:9230074 NOTES: NCD
is described by: http://identifiers.org/pubmed/10421229
modifier: MODEL1109130000#
name: dehydroascorbate transport (uniport)
is: SBO:0000185
reversible: true
is described by: http://identifiers.org/pubmed/2656669
is described by: http://identifiers.org/pubmed/8504756
is version of: ECO:0000269
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#e187c4d8_c533_4951_a491_7ae9f66f3a86
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_85dca8f0_0cd0_42fa_9b96_16a2023d8dec
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a279df38_7fe7_485f_a7b2_3a2cff0f96cd
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0ecbe01d_7082_4992_bb85_e31f477604de
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_242a7e19_fbb7_45cc_8445_3196c2d3a446
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3e76ae0b_5204_4b43_bec8_c738f02fedc0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b7fb463d_a968_4ff3_a046_8a072281b078
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a83b9eae_8b45_4c7a_8817_eca16bf4379a
value: 1000.0
type: LocalParameter

metaR RE0923R
type: Reaction
is version of: http://identifiers.org/ec-code/2.4.1.17
name: RE0923
product: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7263841
is: SBO:0000176
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:7263841 NOTES:
reversible: false
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_83aca721_9904_42ea_b36f_14000b90bddb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f7bda968_379f_4257_ae1d_850359ce46dc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_576cbb25_7ad8_4b8e_881e_63470a0b1956
units: dimensionless
value: 0.0
type: LocalParameter

metaM 13 cis retn c
is: D00348
initial amount: NaN
is: http://identifiers.org/pubchem.substance/7847414
initial concentration: 1.0
boundary condition: false
has only substance units: false
constant: false
is: HMDB06219
type: Species
name: 13-cis-retinoate
notes: FORMULA: C20H27O2 CHARGE: -1 INCHI: InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14- EHMN_ABBREVIATION: CE2952
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#d77fc814_af63_4c62_87a4_28c5e28a3a8b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_435b96c8_5734_4484_8357_a37b4add1ba8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_574532d7_8005_45c3_b8f4_b2ce88ba9f61
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7f3c8bd5_adac_49e0_bcb7_aed1fe77157e
value: 1000.0
type: LocalParameter

metaR RE1441G
is version of: http://identifiers.org/ec-code/2.7.1.68
reactant: MODEL1109130000#
is: SBO:0000176
name: RE1441
product: MODEL1109130000#
reversible: true
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9211928
type: Reaction
is described by: http://identifiers.org/pubmed/10231032
fast: false
is described by: http://identifiers.org/pubmed/10358929
is described by: http://identifiers.org/pubmed/11493657
notes: GENE_ASSOCIATION: (8395.1) or (23396.1) or (8394.1) SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: 2.7.1.68 Confidence Level: 0 AUTHORS: PMID:10231032,PMID:10358929,PMID:11493657,PMID:9211928 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_75194cd7_0fc2_4155_8794_180bbb8290b2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e2622065_2bea_4180_9acd_4c9a9755b022
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c3d23003_ce7a_47ab_9025_068c470cee35
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_93b03c2b_48da_418a_a64c_ef17695a5244
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_136a8a81_1ccf_4782_ab80_a9d514cf56b1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5bef180f_f4f3_44a8_9556_1de2dbc8c853
value: 0.0
type: LocalParameter

metaR RE2799C
is described by: http://identifiers.org/pubmed/12543809
name: RE2799
fast: false
is: SBO:0000176
is described by: http://identifiers.org/pubmed/7948008
is version of: http://identifiers.org/ec-code/1.1.1.188
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: 1.1.1.188 Confidence Level: 0 AUTHORS: PMID:12543809,PMID:7948008 NOTES:
product: MODEL1109130000#
reversible: true
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_736a83eb_5e31_4781_91d6_4dfc0ea6f024
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fbc91587_037f_4865_bc95_5b748d12062d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fca2de51_1581_4589_b26a_ff87985e8239
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5aa1e1bc_49f4_45a4_acfc_4ff05d303cd0
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1b1e4947_eac9_4397_9530_9d588c4ef6cd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_38d87254_f0f5_45e1_b0b1_23ee0092d23a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0bddae51_80e4_4443_9832_76943d5f24e9
value: -1000.0
type: LocalParameter

metaM CE4793 x
boundary condition: false
constant: false
is: SBO:0000247
notes: FORMULA: C41H62N7O18P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE4793
name: 3-oxo-dihomo-gama-linolenoyl-CoA
has only substance units: false
type: Species
initial amount: NaN
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_72308220_bd6f_4a56_99f4_098ed5835cf7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7455252d_0876_44db_8235_d1af78921a18
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_09cfb5f2_0b9d_4df9_8fca_3dd6190b5514
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3837a3ff_bacd_4b81_923b_db45c1cb43e1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_32bc56be_eba9_4cc3_bd0d_24127f338223
value: 1000.0
type: LocalParameter

metaR r1844
name: Y+LAT2 Utilized transport
is described by: http://identifiers.org/pubmed/14770310
reversible: false
is described by: http://identifiers.org/pubmed/14770309
fast: false
is: SBO:0000185
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
reactant: MODEL1109130000#
product: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_f55c534d_0239_4673_b192_e7dd77983063
initial concentration: NaN
constant: true
is: SBO:0000252
is: Q8TCD5
is encoded by: hsa:30833
boundary condition: true
initial amount: NaN
name: NT5C
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_d504442e_7076_4cb5_9eac_7fece581265e
is: SBO:0000252
boundary condition: true
is encoded by: hsa:5213
is: P08237
constant: false
initial concentration: NaN
name: PFKM
has only substance units: false
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#fec8846b_105b_4b3e_bed2_9f54e252d985
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b295a744_a43e_464b_b424_0da0cef5b033
has only substance units: false
type: Species
initial concentration: NaN
is: O75908
initial amount: NaN
is encoded by: hsa:8435
is: SBO:0000252
boundary condition: true
name: SOAT2
constant: true

metaR BPNT2
is version of: http://identifiers.org/ec-code/3.1.3.7
fast: false
reactant: MODEL1109130000#
name: 3,5-bisphosphate nucleotidase (paps)
modifier: MODEL1109130000#
reversible: false
type: Reaction
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 10380.1 SUBSYSTEM: Nucleotide interconversion EC Number: 3.1.3.7 Confidence Level: 4 AUTHORS: PMID:10224133 NOTES:
is described by: http://identifiers.org/pubmed/10224133
is version of: ECO:0000269
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_45245293_8381_409d_828b_cbda0040e00a
value: 1000.0
type: LocalParameter

metaR r1847
is described by: http://identifiers.org/pubmed/14770309
fast: false
is described by: http://identifiers.org/pubmed/14770310
reversible: false
name: Y+LAT2 Utilized transport
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
modifier: MODEL1109130000#
product: MODEL1109130000#
type: Reaction
is: SBO:0000185
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_66533d5b_79e1_44f6_abc6_d7c35afe8067
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9fc5b0ad_e944_4ea7_8f63_713185b8f036
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8b53cf64_1b39_4384_9a4c_847bffe03852
constant: false
initial amount: NaN
type: Species
boundary condition: true
name: NT5C
has only substance units: false
is: Q8TCD5
is: SBO:0000252
initial concentration: NaN
is encoded by: hsa:30833

metaM ditp c
name: dITP(4-)
boundary condition: false
constant: false
initial amount: NaN
notes: FORMULA: C10H11N4O13P3 CHARGE: -4 INCHI: InChI=1S/C10H15N4O13P3/c15-5-1-7(14-4-13-8-9(14)11-3-12-10(8)16)25-6(5)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,15H,1-2H2,(H,20,21)(H,22,23)(H,11,12,16)(H2,17,18,19)/p-4/t5-,6+,7+/m0/s1 EHMN_ABBREVIATION: C01345
has only substance units: false
type: Species
is: SBO:0000247
is: CHEBI:61382
initial concentration: 1.0
is: HMDB03537

http://identifiers.org/biomodels.db/MODEL1109130000#f1a07381_16c3_47fe_bf7e_0e9903728247
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be762d7e_17d6_41c1_b863_e90db918bd6e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5c9f5cdb_b104_4a31_b2bb_70b226f9f34e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f36ce5bf_5fbd_4f93_9b59_b38a63f87932
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_41367f77_b8b0_4e6d_95d0_96b06deea351
value: 0.0
type: LocalParameter

metaM CE2888 c
has only substance units: false
initial amount: NaN
name: 3,5-diiodothyroacetate-beta-D-glucuronoside
notes: FORMULA: C20H16I2O10 CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE2888
is: SBO:0000247
initial concentration: 1.0
boundary condition: false
constant: false
type: Species

metaR CYANtm
name: Cyanide transport via diffusion (mitochondrial)
is version of: ECO:0000000
product: MODEL1109130000#
reversible: true
is: SBO:0000185
reactant: MODEL1109130000#
fast: false
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 0 AUTHORS: NOTES: assumed to be readily diffusible MM

http://identifiers.org/biomodels.db/MODEL1109130000#_99f3c8f5_455e_4bb2_943c_def9d3be61c2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d509b544_40e3_49d6_a02c_6730b02dc4ed
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1846
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
is: SBO:0000185
name: Y+LAT2 Utilized transport
product: MODEL1109130000#
fast: false
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310

http://identifiers.org/biomodels.db/MODEL1109130000#_3f7f7488_aebd_4f81_b37f_b01143f416b9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e01675c7_1a2b_4104_937d_7b643ea2cd43
value: -1000.0
type: LocalParameter

metaR EX ribflv LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for Riboflavin
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#ba8b36a3_6ffd_4e67_ab26_fd83efbf4cda
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3d1336b9_7cf0_4810_a32d_b60aeb30db53
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_962ea770_532d_4de1_9f6e_bc4f27ca828c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3eb39afc_64bc_4aa9_a990_bef9fb2edca4
initial amount: NaN
is: SBO:0000252
has only substance units: false
is: O43822
is encoded by: hsa:755
name: C21orf2
boundary condition: true
constant: false
initial concentration: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_bf0f4fc8_ac4c_4cf1_9224_fb69ef4361d2
is encoded by: hsa:5293
constant: true
has only substance units: false
type: Species
boundary condition: true
initial amount: NaN
name: PIK3CD:PIK3R1
is encoded by: hsa:5295
has part: A7E2E0
initial concentration: NaN
is: SBO:0000297

http://identifiers.org/biomodels.db/MODEL1109130000#_4b55d67b_fcf1_4dfd_b6e2_f4c2462276c9
initial amount: NaN
is: SBO:0000252
has only substance units: false
type: Species
is encoded by: hsa:4017
boundary condition: true
initial concentration: NaN
name: LOXL2
is: Q9Y4K0
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_a3991edb_51d4_4095_9ea7_e78010d75e60
boundary condition: true
type: Species
constant: true
name: B4GALT5
has only substance units: false
initial amount: NaN
is encoded by: hsa:9334
is: O43286
is: SBO:0000252
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_84fff94a_f53a_4048_8f21_f1f8cba50578
has only substance units: false
name: SLC6A1
boundary condition: true
initial concentration: NaN
type: Species
constant: false
is encoded by: hsa:6529
is: SBO:0000252
is: P30531
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#d64d3924_310a_44c0_81bf_8989ef5241c4
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE2240C
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin D metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:12466393,PMID:12485911 NOTES:
reversible: false
name: RE2240
is: SBO:0000176
fast: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12485911
is described by: http://identifiers.org/pubmed/12466393
reactant: MODEL1109130000#
type: Reaction

metaR r1841
reversible: false
name: Y+LAT2 Utilized transport
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
is: SBO:0000185
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
modifier: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#e446ced1_aac3_4884_a7bc_81b856b18902
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_61b9fb18_e4a4_447a_860b_305d5300db7e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d3dbab8a_5c7d_4b62_89ef_4b5deaaee9c7
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4cc4c231_9306_4e37_8ddd_886d20b528b0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_48649d61_bfd1_42a3_9427_24fda9cec6ff
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1d4ef0f0_7314_405f_8955_8f3ee9dab730
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0ce72c4b_80b8_4bac_9b04_7483f7da3f3c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e5c0f536_ebdd_43e8_81ae_b7f0c113f590
value: 0.0
type: LocalParameter

metaR TMNDNCCOAtx
is: SBO:0000185
reactant: MODEL1109130000#
product: MODEL1109130000#
name: fatty acid intracellular transport
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, peroxisomal EC Number: Confidence Level: 2 AUTHORS: NOTES: interaction between peroxisomes and ER (some enzymes on the outer membrane) NJ
fast: false
is version of: ECO:0000000
reversible: true
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_21610899_3bc0_43ba_bf63_e5b0eef4e7de
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ae43b273_0b5c_4aa3_b541_ab0659913608
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e71a06fb_af82_49a7_aaba_b5d5ef93e132
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9418a0c2_4419_452d_84c7_45cfa9aab4a2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_106dfc20_7a6f_4ae0_8ca4_fe4faabad426
initial amount: NaN
is encoded by: hsa:7001
constant: true
has only substance units: false
type: Species
boundary condition: true
initial concentration: NaN
name: PRDX2
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_dbf77886_71b2_4bfc_a32e_c2424c86cd9e
type: Species
has only substance units: false
constant: false
is: Q8NFW8
initial concentration: NaN
is encoded by: hsa:55907
name: CMAS
is: SBO:0000252
initial amount: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#b38692da_62fd_43c9_ace5_228378938905
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_462f0155_94af_4389_97a1_26ea6ec9a2d0
constant: false
has only substance units: false
is: SBO:0000252
is: Q9BR01
is encoded by: hsa:25830
type: Species
boundary condition: true
name: SULT4A1
initial concentration: NaN
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_3495d3eb_c41d_4986_b688_f551b92b8072
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_75c4383a_2032_46fe_80ed_c9d7b59fd585
value: 1000.0
type: LocalParameter

metaM rnam c
is: HMDB00855
is: CHEBI:15927
is: SBO:0000247
name: N-Ribosylnicotinamide
notes: FORMULA: C11H15N2O5 CHARGE: 1 INCHI: InChI=1S/C11H14N2O5/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11/h1-4,7-9,11,14-16H,5H2,(H-,12,17)/p+1/t7-,8-,9-,11-/m1/s1 EHMN_ABBREVIATION: C03150
type: Species
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_0e1a001c_748a_4d56_941c_e3d9ad657e38
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fcba6c62_5cf5_4d3b_a1ff_d60234525c9b
value: 0.0
type: LocalParameter

metaR RE3229C
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
fast: false
name: RE3229
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
reversible: true
is described by: http://identifiers.org/pubmed/10970790
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_6e5bb75d_5a29_45bb_8971_8f7e97957397
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d497c2d0_e5fb_496c_b659_ef61ad94acc3
boundary condition: true
initial concentration: NaN
type: Species
is: SBO:0000297
has part: E5KS60
constant: false
initial amount: NaN
name: SUCLG1:SUCLA2
is encoded by: hsa:8803
has only substance units: false

metaR RE2404C
product: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/10191290
reactant: MODEL1109130000#
fast: false
reversible: false
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Miscellaneous EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:10191290 NOTES:
type: Reaction
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.4.1.17
name: RE2404

http://identifiers.org/biomodels.db/MODEL1109130000#_6b94d305_219e_49d8_9bc3_7f21ab048ba0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1dd8f0ae_20fc_4e72_a3d6_7de74cd87297
initial concentration: NaN
constant: true
has only substance units: false
boundary condition: true
name: SLC8A3
is: B3KU59
is: SBO:0000252
is encoded by: hsa:6547
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#d0b3ef94_0672_4bc0_a2b9_dcbced37aefb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#db5f0bb2_293a_4aac_8db9_4df02c3c31b7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_24aa9762_568b_44db_ad0e_83f17bb8c30a
has only substance units: false
boundary condition: true
type: Species
name: UCK2
initial concentration: NaN
initial amount: NaN
is: SBO:0000252
is: Q9BZX2
is encoded by: hsa:7371
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#fc20424c_25ba_4a05_a6d4_47bdd3cfa312
value: 0.0
type: LocalParameter

metaR r1843
modifier: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
reactant: MODEL1109130000#
reversible: false
type: Reaction
name: Y+LAT2 Utilized transport
fast: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185

metaM 34hpl m
type: Species
initial concentration: 1.0
notes: FORMULA: C9H9O4 CHARGE: -1 INCHI: InChI=1S/C9H10O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8,10-11H,5H2,(H,12,13)/p-1
boundary condition: false
constant: false
is: HMDB00755
is: SBO:0000247
initial amount: NaN
has only substance units: false
is: CHEBI:36659
name: 3-(4-hydroxyphenyl)lactate

http://identifiers.org/biomodels.db/MODEL1109130000#_81698172_1cdf_4df5_97a0_f6331fcb7c79
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_35c6d230_b443_415b_98cc_f8748d8715b0
value: -1000.0
type: LocalParameter

metaM CE5026 x
notes: FORMULA: C19H25N4O10S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5026
is: SBO:0000247
name: 5-S-glutathionyl-L-DOPA
boundary condition: false
constant: false
initial concentration: 1.0
type: Species
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_86fa154b_b40c_4987_8d12_bded981df1e1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a8e85e89_cbcf_48a9_b465_70e1ac2c45ef
constant: false
is: Q6IBC0
initial amount: NaN
initial concentration: NaN
type: Species
has only substance units: false
is: SBO:0000252
name: HMGCL
boundary condition: true
is encoded by: hsa:3155

http://identifiers.org/biomodels.db/MODEL1109130000#_9a5cfc54_5125_48df_8944_98b7d9489399
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

metaR r1842
is described by: http://identifiers.org/pubmed/14770310
reversible: false
fast: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
is: SBO:0000185
reactant: MODEL1109130000#
modifier: MODEL1109130000#
type: Reaction
name: Y+LAT2 Utilized transport

http://identifiers.org/biomodels.db/MODEL1109130000#_44284371_5691_457a_89ea_600e988e7f5d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6832f4f6_5fdf_4795_87fe_68bc3f16df3d
value: 0.0
type: LocalParameter

metaR r2136
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12811560 NOTES:
fast: false
is: SBO:0000185
modifier: MODEL1109130000#
reversible: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12811560
product: MODEL1109130000#
type: Reaction
name: Major Facilitator(MFS) TCDB:2.A.1.14.6

http://identifiers.org/biomodels.db/MODEL1109130000#_6092a02a_32c3_4883_96dc_a68eff2f28d7
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3578fc48_cac3_44c7_bfa5_6f9a3a23283c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_54d929b4_bafe_4f09_938d_5aa4a193d7ef
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8bb7a14_4e1d_44f8_8246_8ca7005fce81
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4c412e77_2ccf_4261_bf5a_37a555b7f69d
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX ha LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: hyaluronan exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_9f5f2767_1ff9_4a8b_b495_f7d08f9e30ce
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d8018a1e_a9d0_4477_8e4a_1e685393a5e0
name: EPHX2
is encoded by: hsa:2053
has only substance units: false
boundary condition: true
initial concentration: NaN
initial amount: NaN
constant: true
type: Species
is: SBO:0000252
is: P34913

http://identifiers.org/biomodels.db/MODEL1109130000#_18d0787e_dbdd_4553_8ae0_711129fb6184
units: dimensionless
value: 0.0
type: LocalParameter

metaM 3snpyr c
notes: FORMULA: C3H2O5S CHARGE: -2 INCHI: InChI=1S/C3H4O5S/c4-2(3(5)6)1-9(7)8/h1H2,(H,5,6)(H,7,8) EHMN_ABBREVIATION: C05527
initial concentration: 1.0
initial amount: NaN
boundary condition: false
is: HMDB02332
is: SBO:0000247
has only substance units: false
type: Species
constant: false
name: 3-Sulfinopyruvate
is: CHEBI:1665

http://identifiers.org/biomodels.db/MODEL1109130000#_94deb6ba_da40_428c_88ef_cc4e7aa47a56
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#df2cc701_d47e_4095_ad74_99a5ddbfdf48
value: 1000.0
type: LocalParameter

metaM ditp n
initial concentration: 1.0
type: Species
has only substance units: false
notes: FORMULA: C10H11N4O13P3 CHARGE: -4 INCHI: InChI=1S/C10H15N4O13P3/c15-5-1-7(14-4-13-8-9(14)11-3-12-10(8)16)25-6(5)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,15H,1-2H2,(H,20,21)(H,22,23)(H,11,12,16)(H2,17,18,19)/p-4/t5-,6+,7+/m0/s1 EHMN_ABBREVIATION: C01345
is: HMDB03537
boundary condition: false
constant: false
name: dITP(4-)
is: SBO:0000247
initial amount: NaN
is: CHEBI:61382

http://identifiers.org/biomodels.db/MODEL1109130000#a37d7e41_7fca_4991_b394_f489e47791ca
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cdee1d69_b9ce_4bd1_b468_2d8b631db480
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7f8f1c2b_733e_403b_9390_fd5393a68aee
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e84b912e_b7d9_4a4a_9732_8e8cbadba4b8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3832a317_f66d_4603_bf8c_1a82f25ab658
value: 0.0
type: LocalParameter

metaM CE2172 c
is: HMDB06044
initial amount: NaN
initial concentration: 1.0
name: 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
notes: FORMULA: C9H12NO2 CHARGE: 1 INCHI: InChI=1/C9H11NO2/c11-8-3-6-1-2-10-5-7(6)4-9(8)12/h3-4,10-12H,1-2,5H2 EHMN_ABBREVIATION: CE2172
has only substance units: false
type: Species
constant: false
boundary condition: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_6e8e2179_74ff_451b_938d_c4e78ad94082
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4e9465f5_aae4_4437_ac90_89a216abf9a2
value: -1000.0
type: LocalParameter

metaR ENGASE
type: Reaction
is described by: http://identifiers.org/pubmed/12114544
product: MODEL1109130000#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/3.2.1.96
is version of: ECO:0000000
notes: GENE_ASSOCIATION: 64772.1 SUBSYSTEM: N-glycan degradation EC Number: 3.2.1.96 Confidence Level: 0 AUTHORS: PMID:12114544 NOTES: NCD
reversible: false
name: endo-beta-N-acetylglucosaminidase
modifier: MODEL1109130000#
reactant: MODEL1109130000#
fast: false

metaM ditp m
type: Species
has only substance units: false
notes: FORMULA: C10H11N4O13P3 CHARGE: -4 INCHI: InChI=1S/C10H15N4O13P3/c15-5-1-7(14-4-13-8-9(14)11-3-12-10(8)16)25-6(5)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,15H,1-2H2,(H,20,21)(H,22,23)(H,11,12,16)(H2,17,18,19)/p-4/t5-,6+,7+/m0/s1 EHMN_ABBREVIATION: C01345
is: CHEBI:61382
initial concentration: 1.0
constant: false
is: SBO:0000247
initial amount: NaN
boundary condition: false
name: dITP(4-)
is: HMDB03537

metaR RE1956C
name: RE1956
is version of: http://identifiers.org/ec-code/3.3.2.9
is described by: http://identifiers.org/pubmed/11323741
reactant: MODEL1109130000#
reversible: true
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/9870464
modifier: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 2053.1 SUBSYSTEM: Arachidonic acid metabolism EC Number: 3.3.2.9 Confidence Level: 0 AUTHORS: PMID:11323741,PMID:9870464 NOTES:
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#fa8dbb15_9ede_4397_b278_86baedc0ded2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31e6f020_b8e2_40fb_80ec_4d273bd29bdb
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c89e24c9_f196_438c_b76a_d250bc02f75e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_477aeda8_a610_40f3_bb49_41a696f4e797
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b6dcee39_073c_433c_8341_79ec3611b026
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_42d71a16_591e_46cb_a479_586152bf05eb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_42bcfff6_1fb2_4462_b330_c268ce498e66
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7f8a919f_8082_4390_8536_dfdef615f7d7
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_12a63885_c061_4312_91c0_032ee6895275
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d8e43544_ff90_4bc4_957e_438856daba88
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_485873ef_111b_460f_8716_537a2565ff0f
boundary condition: true
is encoded by: hsa:64077
initial concentration: NaN
type: Species
is: Q9H008
has only substance units: false
is: SBO:0000252
name: LHPP
initial amount: NaN
constant: false

metaM CE7087 c
initial concentration: 1.0
name: leukotriene D5
type: Species
initial amount: NaN
notes: FORMULA: C25H37N2O6S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE7087
constant: false
has only substance units: false
boundary condition: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_07b5bf35_2002_4005_8974_7935be732490
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_644f1a98_842a_411f_a251_ded867a02b8e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_fc5ec440_7aa9_41d0_b152_41c18f8cb4c1
type: Species
initial amount: NaN
is encoded by: hsa:5289
name: PIK3C3
is: SBO:0000252
has only substance units: false
boundary condition: true
constant: false
is: Q8NEB9
initial concentration: NaN

metaR r2133
is: SBO:0000185
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/12739169
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
fast: false
reactant: MODEL1109130000#
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_468f2bb1_f6a8_4caa_b263_1a36fd460fd1
type: Species
has only substance units: false
initial amount: NaN
name: AMDHD2
boundary condition: true
constant: false
is encoded by: hsa:51005
initial concentration: NaN
is: SBO:0000252
is: Q9Y303

metaR RE1441R
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10231032
is: SBO:0000176
is described by: http://identifiers.org/pubmed/11493657
type: Reaction
reversible: true
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10358929
is described by: http://identifiers.org/pubmed/9211928
is version of: http://identifiers.org/ec-code/2.7.1.68
notes: GENE_ASSOCIATION: (5305.1) or (8396.1) or (79837.1) SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: 2.7.1.68 Confidence Level: 0 AUTHORS: PMID:10231032,PMID:10358929,PMID:11493657,PMID:9211928 NOTES:
fast: false
name: RE1441
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#ebc87883_45fe_4a70_a0d5_bcbecbabeae9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a4eb7b37_96ad_4876_ad86_48b55ccf7d3b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_89772bb3_9fc3_4356_92d5_192ad413ef7d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d00e157c_2bdf_440e_aaac_ee54d884e796
value: 0.0
type: LocalParameter

metaM 13 cis retn n
initial amount: NaN
has only substance units: false
name: 13-cis-retinoate
boundary condition: false
is: SBO:0000247
initial concentration: 1.0
type: Species
is: http://identifiers.org/pubchem.substance/7847414
is: HMDB06219
is: D00348
notes: FORMULA: C20H27O2 CHARGE: -1 INCHI: InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14- EHMN_ABBREVIATION: CE2952
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_7b88fbe7_de3a_46e9_b99a_5cc53c9f336c
value: 0.0
type: LocalParameter

metaM C05300 r
has only substance units: false
initial concentration: 1.0
type: Species
constant: false
notes: FORMULA: C18H22O3 CHARGE: 0 INCHI: InChI=1S/C18H22O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-16,19-20H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,18+/m1/s1 EHMN_ABBREVIATION: C05300
boundary condition: false
is: CHEBI:776
initial amount: NaN
is: SBO:0000247
is: HMDB00335
name: 16alpha-Hydroxyestrone

http://identifiers.org/biomodels.db/MODEL1109130000#_8f092922_7f8a_4b8f_a55c_6a93c759dcd1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f3958dc5_7003_442b_881c_945298ffef5b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bac011a4_65a6_4e09_9e41_9fcada3211fe
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69830471_d165_47cf_96ae_59b277b37d1f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_57c3560c_f35c_437f_a733_820231e1115f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e3f5aeff_0766_4f96_9048_e5e433cfeffd
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_52132455_9eee_4d81_8ad3_55146ad0fc7a
value: 0.0
type: LocalParameter

metaR r2132
type: Reaction
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
reactant: MODEL1109130000#
is: SBO:0000185
reversible: true
is described by: http://identifiers.org/pubmed/12739169
product: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
fast: false
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#ef9c66df_864e_4fde_8b74_f090c72b178a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5e1412d7_33c4_4437_adec_f9757a7fdf5e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#af979af2_56be_4bda_89e1_04fb282edd2f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2a95ac27_72f7_4118_9540_6cee39df9f63
is encoded by: hsa:AI924226
initial amount: NaN
initial concentration: NaN
boundary condition: true
name: _AI924226_1_m
constant: false
type: Species
has only substance units: false
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_4da60fa0_8f9e_4505_8d25_c7ff7e2bd0cc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a3dfe974_2b72_4e55_865d_f9fc1d343baa
value: 0.0
type: LocalParameter

metaM adpac x
name: adipic acid
is: HMDB00448
has only substance units: false
notes: FORMULA: C6H8O4 CHARGE: -2
constant: false
initial amount: NaN
type: Species
initial concentration: 1.0
boundary condition: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_e80e03fb_548f_406b_94bf_a0ce15c74a00
is encoded by: hsa:218
is: SBO:0000252
boundary condition: true
name: ALDH3A1
constant: false
notes: DRUGBANK_UNKNOWN: DB00157, DB01907
is: P30838
has only substance units: false
initial concentration: NaN
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_3f06e7a0_3399_46f7_8016_1a919612d2cf
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE2888 r
constant: false
initial amount: NaN
type: Species
notes: FORMULA: C20H16I2O10 CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE2888
has only substance units: false
boundary condition: false
is: SBO:0000247
initial concentration: 1.0
name: 3,5-diiodothyroacetate-beta-D-glucuronoside

metaR r1848
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
reactant: MODEL1109130000#
modifier: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/14770309
is: SBO:0000185
name: Y+LAT2 Utilized transport
fast: false
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/14770310

metaR r2131
product: MODEL1109130000#
is: SBO:0000185
type: Reaction
is described by: http://identifiers.org/pubmed/12739169
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
fast: false
modifier: MODEL1109130000#
reactant: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:

metaR r2130
reactant: MODEL1109130000#
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:12739169 NOTES:
product: MODEL1109130000#
name: Major Facilitator(MFS) TCDB:2.A.1.13.1
is described by: http://identifiers.org/pubmed/12739169
is: SBO:0000185
reversible: true
fast: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_0147b73b_8383_4acf_925f_0b2235ff1669
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b8c423fd_21d9_4ded_a671_8fd222fdb6f6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0a75e78e_0569_4e48_8d2c_6416febc1a4f
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bea7dcb5_0093_42de_9d97_5d860cab1884
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#df0b7cc5_1e65_4bbf_b6ca_77be37386aa0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_39f9c855_3730_455b_a010_60498927cc19
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#df0016f7_1038_461e_bd08_70349f6bf59e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be418553_a65e_47f6_8cbd_1d95137273f4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d0c27235_9e58_42c4_a767_b343a88cc67f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d8631dc4_0d65_4b88_a0f0_9592ac73127b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_e2eedf31_a1b2_4c97_b6c8_e0fa4216a2a9
is encoded by: hsa:9197
type: Species
is: SBO:0000252
constant: false
boundary condition: true
initial amount: NaN
initial concentration: NaN
name: SLC33A1
is: O00400
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#f3d1e6ab_8de8_40f0_9977_e39e0dc7e8a8
value: -1000.0
type: LocalParameter

metaR TYMSULT
name: Tyramine Sulfotransferase
reactant: MODEL1109130000#
modifier: MODEL1109130000#
reversible: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: (6818.3) or (6818.1) or (6817.4) or (6817.1) or (6817.3) or (6818.2) or (6817.2) or (6817.5) SUBSYSTEM: Tyrosine metabolism EC Number: 2.8.2.1 Confidence Level: 4 AUTHORS: PMID:11535246,PMID:15293241 NOTES: TV/RS (6/14/05)
is described by: http://identifiers.org/pubmed/11535246
is: SBO:0000176
fast: false
is version of: ECO:0000269
is version of: http://identifiers.org/ec-code/2.8.2.1
type: Reaction
is described by: http://identifiers.org/pubmed/15293241

http://identifiers.org/biomodels.db/MODEL1109130000#_35321b2b_48e1_4ac5_bfa4_844664d0023c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf0da420_d15c_4061_bfbb_609f0415cc63
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2df3b667_a593_475f_a091_07987ae71dc7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_49d4c3d6_9a1a_46b6_84ab_b92cd1b7cbdb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5469fc9a_1ad7_4a70_8b96_9f5f00528d90
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_cab48e53_2981_4546_9fb5_f76e06b092ed
is encoded by: hsa:27235
is: Q96H96
initial amount: NaN
is: SBO:0000252
has only substance units: false
initial concentration: NaN
constant: true
type: Species
boundary condition: true
name: COQ2

http://identifiers.org/biomodels.db/MODEL1109130000#_7f31c066_b249_4cbd_aa18_3d7647ec3054
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a974b0c8_6ba9_4394_9a7e_196d19b17952
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0c5f82e1_ed53_4a73_88f2_01abe55a5bde
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fcfd7230_c550_456e_8297_96a977739b60
value: 1000.0
type: LocalParameter

metaM 13 cis retn r
name: 13-cis-retinoate
constant: false
boundary condition: false
notes: FORMULA: C20H27O2 CHARGE: -1 INCHI: InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14- EHMN_ABBREVIATION: CE2952
is: HMDB06219
initial amount: NaN
type: Species
is: SBO:0000247
is: http://identifiers.org/pubchem.substance/7847414
has only substance units: false
is: D00348
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_9ddb3fe3_247d_446f_be12_fd823f20f88d
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a8fa513c_5c7d_45be_ae58_99865f00588e
value: 0.0
type: LocalParameter

metaR EX dad 2 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: exchange reaction for 2-deoxyadenosine
type: Reaction

metaR RE0924C
is: SBO:0000176
is described by: http://identifiers.org/pubmed/3090812
reversible: false
is described by: http://identifiers.org/pubmed/7364927
is described by: http://identifiers.org/pubmed/9633995
is described by: http://identifiers.org/pubmed/8070342
type: Reaction
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:3090812,PMID:7364927,PMID:8070342,PMID:9633995 NOTES:
name: RE0924
fast: false
is version of: http://identifiers.org/ec-code/2.4.1.17
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_9f0882b6_23c9_43f2_a86d_62ba398bac00
value: 1000.0
type: LocalParameter

metaR HMGCOAtm
reactant: MODEL1109130000#
is version of: ECO:0000000
is: SBO:0000185
fast: false
type: Reaction
reversible: true
name: Hydroxymethylglutaryl-CoA reversible mitochondrial transport
is described by: http://identifiers.org/pubmed/14713247
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, mitochondrial EC Number: Confidence Level: 2 AUTHORS: PMID:14713247 NOTES: NCD

http://identifiers.org/biomodels.db/MODEL1109130000#bc533812_d315_4ce4_8f70_3933edc1b658
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a0a66347_7ba1_45dc_8783_6600dd78fabb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5f5720c6_33cb_46ac_81cc_aeb2a999f386
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a4620d6d_d658_417c_b17a_e82dd8fe1ca4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9f4e4c8a_44c5_411f_8ae0_6d20048a132a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#efeb7da3_7c58_4d6b_be2c_02a6582fda0e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e64f05ff_1e0a_45ec_9c0c_468148ff0f4d
value: 1000.0
type: LocalParameter

metaR DOCOSDIACTD
is: SBO:0000185
is described by: http://identifiers.org/pubmed/15716582
reactant: MODEL1109130000#
product: MODEL1109130000#
reversible: true
fast: false
type: Reaction
name: excretion of docosanedioic acid
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 2 AUTHORS: PMID: 15716582 EC Number: NOTES: high levels may be excreted in urine in case of peroxisomal biogenesis disorders GENE_ASSOCIATION:

metaR RE2638C
reactant: MODEL1109130000#
name: RE2638
modifier: MODEL1109130000#
product: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 570.1 SUBSYSTEM: Bile acid synthesis EC Number: 2.3.1.65 Confidence Level: 0 AUTHORS: PMID:11980911 NOTES:
is: SBO:0000176
is described by: http://identifiers.org/pubmed/11980911
is version of: http://identifiers.org/ec-code/2.3.1.65
reversible: true
type: Reaction

metaR r2149
reactant: MODEL1109130000#
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
is: SBO:0000185
modifier: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:
is described by: http://identifiers.org/pubmed/11076396
type: Reaction
reversible: true
is described by: http://identifiers.org/pubmed/14579113
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11076394

http://identifiers.org/biomodels.db/MODEL1109130000#_297a3d95_4c89_4485_ad16_aca11da4eca1
is encoded by: hsa:80724
boundary condition: true
initial concentration: NaN
has only substance units: false
initial amount: NaN
constant: true
is: Q6JQN1
is: SBO:0000252
name: ACAD10
type: Species

metaM 2hexdtetcoa m
is: SBO:0000247
name: 2,7,10,13-hexadecatetraenoylcoa
has only substance units: false
initial concentration: 1.0
initial amount: NaN
constant: false
notes: FORMULA: C37H54N7O17P3S CHARGE: -4
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_0d7aa243_daec_4b0d_a666_0f273fc483fc
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#da76e448_b13a_4707_9cb1_9bbaddaf7c64
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c00b8408_e570_4aaf_ac99_d41ed1e8b2b3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_803cb5c6_531c_4705_9787_3e7908309141
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c85ce5cb_b073_4da0_8167_2c3d555f140b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f77f8b4_5a01_4100_a883_0622c2405395
initial amount: NaN
is: SBO:0000252
type: Species
is: Q5QPH3
is encoded by: hsa:55902
boundary condition: true
has only substance units: false
name: ACSS2
constant: false
initial concentration: NaN

metaR S6TASE16ly
modifier: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3196333
notes: GENE_ASSOCIATION: 2799.1 SUBSYSTEM: Keratan sulfate degradation EC Number: 3.1.6.14 Confidence Level: 4 AUTHORS: PMID:3196333,PMID:3689314,PMID:3689315 NOTES: NCD
is: SBO:0000176
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/3689314
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/3.1.6.14
is described by: http://identifiers.org/pubmed/3689315
reactant: MODEL1109130000#
name: N-acetylglucosamine-6-sulfatase, lysosomal

http://identifiers.org/biomodels.db/MODEL1109130000#_fa329d4a_4fc0_49d7_91dc_ef9913417e56
is: Q96CA6
has only substance units: false
constant: false
initial concentration: NaN
type: Species
boundary condition: true
initial amount: NaN
is encoded by: hsa:30
is: SBO:0000252
name: ACAA1

http://identifiers.org/biomodels.db/MODEL1109130000#d6095cf2_f209_4e6a_980e_11c004d7147c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b067374f_d9b1_4740_9fac_f47396db0a22
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6fd59c34_31f5_4e4b_835e_988fdce545bd
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

metaR DLNLCGCPT1
fast: false
notes: GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: NOTES: NJ
reversible: false
is version of: ECO:0000000
type: Reaction
is version of: http://identifiers.org/ec-code/2.3.1.21
name: carnitine O-palmitoyltransferase
product: MODEL1109130000#
is: SBO:0000176
reactant: MODEL1109130000#
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_2bb10513_7072_44c4_99f3_fa043605c1d1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_fa64936a_b5a5_46f8_b103_78961bf3c41d
type: Species
name: PCYT2
initial amount: NaN
initial concentration: NaN
is: SBO:0000252
has only substance units: false
constant: false
is encoded by: hsa:5833
boundary condition: true
is: F5H8B1

http://identifiers.org/biomodels.db/MODEL1109130000#b41d25b5_01c7_4399_90ec_41a9f3c0260a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7d6eaca7_858f_49df_a342_7914b727f7c6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9df0f6c4_627b_4a83_a6ef_a80ff1d981d1
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e3332443_f862_4085_a7f6_625cc735b864
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4b728140_850c_4419_acae_e6d5bd9f6f78
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_46e83aff_2a98_4c38_be10_71066451a669
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_153b3dbe_ec22_4839_ac1c_25fbc049b27c
has only substance units: false
is encoded by: hsa:1718
is: SBO:0000252
initial concentration: NaN
initial amount: NaN
boundary condition: true
constant: false
is: Q15392
name: DHCR24
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#a5cdced8_c58c_4805_88d5_53b17783ba79
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bc95f2bc_1095_4bd8_8b7d_d4e512d3b8c3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf78c343_c3a4_4cc8_8a72_227c18a69c90
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_10f39a3d_0738_4dae_b7fc_3e59dc8d7d3b
value: 1000.0
type: LocalParameter

metaR 5ADTSTSTERONESte
is: SBO:0000185
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 1 AUTHORS: NOTES: unknown mechanism - presumed excretion of sulfonated testosterone NJ
name: sulfonated testosterone transport
product: MODEL1109130000#
fast: false
reversible: true
is version of: ECO:0000000
reactant: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#b107ebdb_a585_450c_9ace_77e834d201ae
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6f9fae8a_66cd_4199_a178_6785ed5fb7f9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5e271f4c_5ee3_4451_873f_360a4ae213ac
value: 0.0
type: LocalParameter

metaR DLNLCGCPT2
reversible: false
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: Confidence Level: 4 AUTHORS: NOTES: NJ
type: Reaction
fast: false
modifier: MODEL1109130000#
name: carnitine transferase
product: MODEL1109130000#
is: SBO:0000176
is version of: ECO:0000000
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_4a194445_26f8_4c00_9a34_d7fcc65e0e9f
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c597a7b0_1599_4244_bb46_cdbb54990592
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_74b1b9da_c777_42d1_8da9_20f3aa1a80fa
initial amount: NaN
is: SBO:0000252
is encoded by: hsa:79646
has only substance units: false
type: Species
constant: false
boundary condition: true
initial concentration: NaN
is: Q9H999
name: PANK3

http://identifiers.org/biomodels.db/MODEL1109130000#_32feb734_8c8d_4713_8adc_8c27b29f64ab
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0769daab_0a51_4202_885a_cff629db2d1a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ae623e2f_d07e_4ba3_8cfc_0f33ca65c718
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d31c0b5d_0c42_47c6_ba6c_89c1686f946c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_48c122e3_769a_4ed7_8c4e_4be0aa2366e1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8d082a43_a866_4556_84d8_47a4914c54ff
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e6729410_11d5_4716_841f_612b19437517
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX xoltri24 LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: 7-alpha,24(S)-Dihydroxycholesterol exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_2a369c19_3725_4d92_b592_d535c369d75f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_f1a92f2f_7f9f_4371_ae5b_4ba9ccffada6
name: _AW299740_1_m
constant: false
is encoded by: hsa:AW299740
has only substance units: false
is: SBO:0000252
boundary condition: true
initial amount: NaN
initial concentration: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#bc7dac7e_b795_46b9_aa47_7a5195069337
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bab85b56_7313_4343_b6e5_6b21327e74a6
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_79276983_966e_4f28_8cd9_e406c38dd082
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1a6accce_b8da_4a26_beb0_d2bee33dde41
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE5026 c
initial concentration: 1.0
boundary condition: false
constant: false
is: SBO:0000247
has only substance units: false
notes: FORMULA: C19H25N4O10S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5026
initial amount: NaN
name: 5-S-glutathionyl-L-DOPA
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_0d97815d_1f85_40b0_a7e0_26060a1d9add
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f3c22ff6_c4cb_4e2d_af8f_e7e2dbaea056
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_14b7182c_52e4_4d9c_ac98_687419134bf7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_783ec157_b252_4b54_bc67_59b879823ba9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7e1a57fc_0e92_4b9c_92e5_3e2896666c9a
value: -1000.0
type: LocalParameter

metaR ENO
is version of: ECO:0000134
fast: false
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/4.2.1.11
modifier: MODEL1109130000#
is: SBO:0000176
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/6626557
is described by: http://identifiers.org/pubmed/5939
notes: GENE_ASSOCIATION: (2023.1) or (2027.2) or (2027.1) or (2026.1) SUBSYSTEM: Glycolysis/gluconeogenesis EC Number: 4.2.1.11 Confidence Level: 0 AUTHORS: PMID:5939,PMID:6626557 NOTES: SMP
name: enolase
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_46f2b346_14c5_4cf2_ad3e_674effd7bd55
constant: true
name: PNLIPRP2
is: SBO:0000252
boundary condition: true
initial amount: NaN
type: Species
is encoded by: hsa:5408
initial concentration: NaN
is: P54317
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#a6528d9b_9ca5_45f7_9d04_ff09faabcb02
value: 0.0
type: LocalParameter

metaM R3coa hs c
initial concentration: 1.0
name: R group 3 Coenzyme A
boundary condition: false
initial amount: NaN
constant: false
notes: FORMULA: XCO2C21H31N7O15P3S CHARGE: -4 INCHI:
type: Species
has only substance units: false
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#_7d295f32_12a0_487c_a5bd_de0c55efc4ce
notes: DRUGBANK_UNKNOWN: DB02735 DRUGBANK_INHIBITOR: DB06713
is encoded by: hsa:412
initial concentration: NaN
is: SBO:0000252
is: P08842
type: Species
initial amount: NaN
boundary condition: true
constant: false
name: STS
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_869e08c3_2f49_46b7_be39_ea932de56a04
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#aa6331bc_28a6_4728_852b_cc9757e1c47b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_583d6401_d5bb_40be_831a_b1b379354455
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_04a71edd_52b1_406c_9dff_fa45108bdba4
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a293fc7d_65b4_4d10_9f18_67a353700793
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a68de518_ce65_4f67_86a8_443ea34869b1
is: P21217
boundary condition: true
name: FUT3
is encoded by: hsa:2525
is: SBO:0000252
type: Species
initial amount: NaN
has only substance units: false
initial concentration: NaN
constant: false

metaM c12dc x
initial concentration: 1.0
boundary condition: false
has only substance units: false
type: Species
is: SBO:0000247
notes: FORMULA: C19H34NO6 CHARGE: -1
name: dodecanedioyl carnitine
constant: false
initial amount: NaN

metaM cholcoa r
boundary condition: false
is: HMDB01374
initial amount: NaN
is: SBO:0000247
name: choloyl-CoA(4-)
type: Species
constant: false
initial concentration: 1.0
notes: FORMULA: C45H70N7O20P3S CHARGE: -4 INCHI: InChI=1S/C45H74N7O20P3S/c1-23(26-7-8-27-34-28(18-31(55)45(26,27)5)44(4)12-10-25(53)16-24(44)17-29(34)54)6-9-33(57)76-15-14-47-32(56)11-13-48-41(60)38(59)43(2,3)20-69-75(66,67)72-74(64,65)68-19-30-37(71-73(61,62)63)36(58)42(70-30)52-22-51-35-39(46)49-21-50-40(35)52/h21-31,34,36-38,42,53-55,58-59H,6-20H2,1-5H3,(H,47,56)(H,48,60)(H,64,65)(H,66,67)(H2,46,49,50)(H2,61,62,63)/p-4/t23-,24+,25-,26-,27+,28+,29-,30-,31+,34+,36-,37-,38+,42-,44+,45-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00844 EHMN_ABBREVIATION: C01794
has only substance units: false
is: CHEBI:57373

http://identifiers.org/biomodels.db/MODEL1109130000#_0efe8998_e37f_4697_bd85_7349c574798d
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c749cbb1_7c46_42fa_a734_3365e20a4f4d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_f403a835_30ba_44c9_8e26_086703d43321
initial concentration: NaN
constant: false
name: ALDH1A3
initial amount: NaN
has only substance units: false
is encoded by: hsa:220
is: P47895
is: SBO:0000252
type: Species
boundary condition: true

metaR T2M26DCOAHLm
notes: GENE_ASSOCIATION: (549.1) or (3030.1) and (3032.1) SUBSYSTEM: Limonene and pinene degradation EC Number: 4.2.1.17 Confidence Level: 1 AUTHORS: NOTES: SAB
fast: false
is version of: ECO:0000212
modifier: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
is: SBO:0000176
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/4.2.1.17
name: trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (m)
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_0f73294b_887e_40ec_a438_2371bc2f2775
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f1b854df_6a60_4984_9b63_f28581d0f7a4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_999f8a08_d6e7_4d5e_8dd7_c96375ad4451
initial concentration: NaN
type: Species
constant: false
has only substance units: false
is encoded by: hsa:204
initial amount: NaN
boundary condition: true
name: AK2
is: SBO:0000252

http://identifiers.org/biomodels.db/MODEL1109130000#_5954529e_e803_4f2b_bef2_e08cf5a7f4e9
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE2704C
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin E metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:9789014 NOTES:
reversible: true
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9789014
name: RE2704
fast: false
is: SBO:0000176
product: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#b39e9402_d8b5_44bd_ab1a_e4f078e505b3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9b27ae0e_fecf_47c2_a7fc_eeb9c357a61d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c81ed582_93a2_40c9_bec0_c86790a370c4
units: dimensionless
value: 0.0
type: LocalParameter

metaR EX 4nphsf LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: 4-Nitrophenyl sulfate exchange
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_2b15c6aa_e93e_4b97_8aba_aff7b03d0a75
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4202975b_8e89_4d91_b50b_0d8fd6d32924
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_666ef23e_5dd1_459c_b547_18e5b48ba87d
units: dimensionless
value: 0.0
type: LocalParameter

metaR NACHEX14ly
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/3.2.1.52
is described by: http://identifiers.org/pubmed/11707436
is described by: http://identifiers.org/pubmed/8993162
is version of: ECO:0000000
reversible: false
is described by: http://identifiers.org/pubmed/12706724
type: Reaction
fast: false
notes: GENE_ASSOCIATION: (3073.1 and 3074.1) or (3074.1) or (3073.1) SUBSYSTEM: Keratan sulfate degradation EC Number: 3.2.1.52 Confidence Level: 4 AUTHORS: PMID:10336991,PMID:11707436,PMID:12706724,PMID:8993162 NOTES: NCD
reactant: MODEL1109130000#
is: SBO:0000176
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10336991
name: beta-N-acetylhexosaminidase, lysosomal

http://identifiers.org/biomodels.db/MODEL1109130000#_60faebff_6248_41ad_8ff9_eb48572572f5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f185078e_b4f6_4694_8ed9_2521f24e7ab4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f6294898_1115_4ad9_a96c_9cbcac0823f5
value: 1000.0
type: LocalParameter

metaM CE6243 m
boundary condition: false
type: Species
name: S-(9-deoxy-delta9,12-PGD2)-glutathione
constant: false
is: SBO:0000247
initial amount: NaN
initial concentration: 1.0
notes: FORMULA: C30H45N3O10S CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE6243
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_0c53754d_a66a_4ce3_82b0_bf0b7db392e7
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_235382f4_39ae_445c_9c8c_2d7c0a35cc37
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18e02c77_f752_4e8f_a239_df9aec8ca231
units: dimensionless
value: 0.0
type: LocalParameter

metaR GLU5Km
is described by: http://identifiers.org/pubmed/10037775
fast: false
is version of: ECO:0000254
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.2.11
reactant: MODEL1109130000#
reversible: false
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 5832.1 SUBSYSTEM: Urea cycle EC Number: 2.7.2.11 Confidence Level: 2 AUTHORS: PMID:10037775 NOTES: SAB m
name: glutamate 5-kinase (m)
is: SBO:0000176
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_3576b193_c8a2_41a3_8f99_cd9e4c3343f8
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1ac61cd9_e168_403e_9782_03f657753096
value: 0.0
type: LocalParameter

metaR L LACDcm
name: L-Lactate dehydrogenase, cytosolic/mitochondrial
is described by: http://identifiers.org/pubmed/18831974
product: MODEL1109130000#
is: SBO:0000185
fast: false
modifier: MODEL1109130000#
is version of: ECO:0000000
type: Reaction
reversible: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 124637.1 SUBSYSTEM: Pyruvate metabolism EC Number: Confidence Level: 2 AUTHORS: PMID:18831974 NOTES: NCD/TDV. This reaction exists in yeast, but no evidence could be found this exists in humans. However, there may be intramitochondrial lactate dehydrogenase and lactate transport into mitochondria

http://identifiers.org/biomodels.db/MODEL1109130000#_373127a0_d7be_476d_b8f3_296c24a658a3
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8868479d_7447_4e22_846f_3fa5a4758644
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f4e070c6_f72c_4c8f_8874_f90d67dcaf41
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_41a9933a_7c73_4c5c_9c95_21a488d1b807
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5cbeab42_124f_4db3_a8fd_43ad285945a7
is: SBO:0000252
name: TK1
boundary condition: true
has only substance units: false
initial concentration: NaN
is encoded by: hsa:7083
constant: true
is: P04183
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_6e69caa7_a228_4f7a_80f5_6d82a0b1d936
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4cf80a8c_fb37_479f_86a7_d5a0d1c516e1
units: dimensionless
value: 0.0
type: LocalParameter

metaR GLYGLYCNc
is described by: http://identifiers.org/pubmed/6993048
is: SBO:0000176
modifier: MODEL1109130000#
name: hydrolysis of glycylycine for uptake
reactant: MODEL1109130000#
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 6993048, PMCID: PMC1412501, PMID: 4919261, PMID: 20178671, PMID: 12473676 EC Number: NOTES: Dipeptides and tripeptides enter the brush border of the intestinal mucosal cells, where they are hydrolyzed to free amino acids, which are then transported into hepatic portal vein. Peptides entering by transcellular or paracellular mechanisms elicit allergic reactions to food (Robert K. Murray, David A. Bender, Kathleen M. Botham, Peter J. kennelly, Victor W. Rodwell, P. Anthony Weil (2009) 28th edition, Harpers illustrated biochemistry,Mc Graw Hill, page 462). formation and hydrolysis of diglycine is a reversible process (David L. Nelson, Michael M. Cox, Lehniniger principles of biochemistry (2000), 3rd edition, worth publishers,page 69, figure 3a). CN1 is expressed in brain where as CN2 is more ubiquitously expressed (PMID: 12473676). GENE_ASSOCIATION: (84735.1 or 55748.1)
fast: false
is described by: http://identifiers.org/pubmed/4919261
type: Reaction
is described by: http://identifiers.org/pubmed/12473676
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/20178671
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#f43e1f62_9dd2_4e86_b274_df7adfc86c23
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a530e1cd_945c_4fb4_80bf_e3a7884f11c6
has only substance units: false
is: O95168
initial amount: NaN
initial concentration: NaN
constant: true
type: Species
boundary condition: true
is: SBO:0000252
is encoded by: hsa:4710
name: NDUFB4

metaR RE3021C
type: Reaction
reversible: true
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9862787
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9799565
is: SBO:0000176
is described by: http://identifiers.org/pubmed/11368003
name: RE3021
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11368003,PMID:9799565,PMID:9862787 NOTES:

metaR OLEICFATPtc
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/10518211
is described by: http://identifiers.org/pubmed/9
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/20086080
notes: SUBSYSTEM: Transport, extracellular Confidence Level: 4 AUTHORS: PMID: 10518211, PMID: 20086080, PMID: 12856180, Immun., Endoc. & Metab. Agents in Med. Chem., 2009, 9, 11-17, EC Number: NOTES: major intestinal fatty acid transport protein, may also act in co-ordination with acyl co-A synthetase. The transport is ATP driven, further the transporter itself has fatty acid activating enzymic properties (PMID: 12856180). GENE_ASSOCIATION: 10999.1
is described by: http://identifiers.org/pubmed/12856180
is described by: http://identifiers.org/pubmed/2009
name: uptake of octadecenoate by the enterocytes
reversible: false
reactant: MODEL1109130000#
is: SBO:0000185
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_1ecbcb5c_8510_49d6_bb9c_78cad44cb34e
value: 0.0
type: LocalParameter

metaM CE5151 r
initial concentration: 1.0
has only substance units: false
name: 11-cis-eicosenoyl-CoA
type: Species
notes: FORMULA: C41H68N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5151
constant: false
initial amount: NaN
is: SBO:0000247
boundary condition: false

metaR r1882
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
reversible: false
reactant: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
is: SBO:0000185
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
name: Y+LAT2 Utilized transport
is described by: http://identifiers.org/pubmed/14770310
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#c2f93bab_bbaa_4b08_b9d4_9c6e8348be2a
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

metaR RE3225C
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/10970790
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
name: RE3225
reversible: false
fast: false
reactant: MODEL1109130000#
type: Reaction
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#adf38cb6_2dbf_4326_bd58_6c380e3933b8
value: 0.0
type: LocalParameter

metaR GQ1Btg
is: SBO:0000185
name: gq1b hs intracellular transport
is described by: http://identifiers.org/pubmed/8206147
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, golgi apparatus EC Number: Confidence Level: 1 AUTHORS: PMID:8206147 NOTES: unknown mechanism for transport - intracellular transport occurs, most details are unknown - see for example Varki glycobiology text or numerous reviews (PMID: 8206147) NJ
fast: false
type: Reaction
reversible: true
is version of: ECO:0000000
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_7be12e54_eba3_443c_b5e4_fa74a5644e22
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_296a7328_cdf0_438e_8184_375dd2cb5e69
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a7573021_8543_4e57_933c_ac08a2b00799
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_ebff6c71_c56f_4cb0_a02a_3c632848dabd
constant: false
is: SBO:0000252
initial amount: NaN
has only substance units: false
is encoded by: hsa:1576
is: P08684
name: CYP3A4
boundary condition: true
initial concentration: NaN
type: Species

metaR r1883
is described by: http://identifiers.org/pubmed/14770310
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/14770309
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
reversible: false
name: Y+LAT2 Utilized transport
is: SBO:0000185
modifier: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction

metaR RE2637X
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11980911
type: Reaction
name: RE2637
is version of: http://identifiers.org/ec-code/2.3.1.65
notes: GENE_ASSOCIATION: 570.1 SUBSYSTEM: Bile acid synthesis EC Number: 2.3.1.65 Confidence Level: 0 AUTHORS: PMID:11980911 NOTES:
reactant: MODEL1109130000#
is: SBO:0000176
fast: false
product: MODEL1109130000#
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_3ae00d6d_5aeb_4a4f_909a_360d21bfb257
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e8e19c54_9fae_4112_9fc2_ae93a0b0d5fb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a65df497_888a_4456_a8ca_e0d64796d044
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#db685b3f_2ff7_4177_bc6b_19a6c532722e
value: 1000.0
type: LocalParameter

metaM HC00591 m
initial concentration: 1.0
is: SBO:0000247
is: CHEBI:16769
type: Species
boundary condition: false
constant: false
initial amount: NaN
notes: FORMULA: C5H6NO4 CHARGE: -1 INCHI: InChI=1S/C5H7NO4/c6-4(8)2-1-3(7)5(9)10/h1-2H2,(H2,6,8)(H,9,10)/p-1 EHMN_ABBREVIATION: C00940
has only substance units: false
name: 2-oxoglutaramate

http://identifiers.org/biomodels.db/MODEL1109130000#a36ef6e2_c64a_4277_bd2b_8831f630ab38
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_87e8c333_b068_4af1_886c_d8f9b36ffc3b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d6ea69b1_9222_4632_a07a_74304f7b530a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7d855d9d_e20e_4900_94dc_33378cf1b433
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_71593821_d1e9_4b56_bdd1_fe645c36e4b9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0cad5b59_71f3_44e9_a722_5758d193bbdd
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_85e99950_93b8_48ec_9656_22a215f859cd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9acabe3d_b559_4bb4_8904_d797f6870649
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c97b3e23_47ea_44bb_81db_e67c11f2347e
value: 0.0
type: LocalParameter

metaR S2TASE2ly
modifier: MODEL1109130000#
name: iduronate-2-sulfatase, lysosomal
reactant: MODEL1109130000#
is: SBO:0000176
is version of: http://identifiers.org/ec-code/3.1.6.13
type: Reaction
is described by: http://identifiers.org/pubmed/8244397
reversible: false
notes: GENE_ASSOCIATION: (3423.1) or (3423.2) SUBSYSTEM: Heparan sulfate degradation EC Number: 3.1.6.13 Confidence Level: 4 AUTHORS: PMID:2122463,PMID:8244397,PMID:8530090,PMID:8993162 NOTES: NCD
fast: false
is described by: http://identifiers.org/pubmed/8530090
is described by: http://identifiers.org/pubmed/2122463
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8993162
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#b616d547_bbdd_4d04_8c49_3fdce0b49cd7
value: 0.0
type: LocalParameter

metaR RE1957R
fast: false
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.7.1.68
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11493657
notes: GENE_ASSOCIATION: (5305.1) or (8396.1) or (79837.1) SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: 2.7.1.68 Confidence Level: 0 AUTHORS: PMID:10231032,PMID:10358929,PMID:11493657,PMID:9211928 NOTES: IT - fixed proton
is described by: http://identifiers.org/pubmed/10231032
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9211928
is: SBO:0000176
is described by: http://identifiers.org/pubmed/10358929
type: Reaction
name: RE1957
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_57a4d88c_5fe9_4502_9c05_346f411c7c23
name: CHDH
boundary condition: true
is: Q8NE62
constant: true
type: Species
is: SBO:0000252
has only substance units: false
initial amount: NaN
is encoded by: hsa:55349
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_56b0aaa0_bfcf_4771_9aba_e21fcffcc106
is: SBO:0000252
type: Species
is encoded by: hsa:4831
is: P22392
has only substance units: false
name: NME2
constant: true
initial amount: NaN
boundary condition: true
initial concentration: NaN

metaM tetde5coa x
initial amount: NaN
type: Species
notes: FORMULA: C35H56N7O17P3S CHARGE: -4
has only substance units: false
initial concentration: 1.0
boundary condition: false
is: SBO:0000247
constant: false
name: 5-tetradecenoylcoa

http://identifiers.org/biomodels.db/MODEL1109130000#aecbad6a_ddb5_4f3a_8331_d6a0abc6c5da
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1880
name: Y+LAT2 Utilized transport
modifier: MODEL1109130000#
type: Reaction
product: MODEL1109130000#
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
fast: false
is described by: http://identifiers.org/pubmed/14770309
is: SBO:0000185
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310

http://identifiers.org/biomodels.db/MODEL1109130000#fd1f4146_8d34_4c68_a684_d9f1093a9034
units: dimensionless
value: 0.0
type: LocalParameter

metaR GQ1Bte
reactant: MODEL1109130000#
is: SBO:0000185
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8206147
name: gq1b hs transport
reversible: true
fast: false
is version of: ECO:0000000
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 1 AUTHORS: PMID:8206147 NOTES: unknown mechanism for transport - intracellular transport occurs, most details are unknown - see for example Varki glycobiology text or numerous reviews (PMID: 8206147) - extracellular transport is also made available since metabolites can get to outer plasma membrane NJ

http://identifiers.org/biomodels.db/MODEL1109130000#ce62164e_69ee_46f4_b814_465ffa0d4b78
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_878985d5_c9dd_42ad_9455_39b07d825a95
value: -1000.0
type: LocalParameter

metaR GALt4
is: SBO:0000185
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 200010.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:12748858,PMID:15607332 NOTES: NCD
reactant: MODEL1109130000#
modifier: MODEL1109130000#
fast: false
reversible: true
type: Reaction
is described by: http://identifiers.org/pubmed/12748858
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/15607332
name: galactose transport via sodium symport

http://identifiers.org/biomodels.db/MODEL1109130000#_1a8055a0_cd93_4a4f_b063_3dd0508dae4b
value: 0.0
type: LocalParameter

metaR 3HAO
name: 3-hydroxyanthranilate 3,4-dioxygenase
is version of: http://identifiers.org/ec-code/1.13.11.6
fast: false
is: SBO:0000176
modifier: MODEL1109130000#
reversible: false
notes: GENE_ASSOCIATION: 23498.1 SUBSYSTEM: Tryptophan metabolism EC Number: 1.13.11.6 Confidence Level: 4 AUTHORS: PMID:7514594 NOTES: NCD
reactant: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7514594
type: Reaction
is version of: ECO:0000269

metaM CE6243 r
is: SBO:0000247
boundary condition: false
type: Species
notes: FORMULA: C30H45N3O10S CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE6243
constant: false
has only substance units: false
initial concentration: 1.0
name: S-(9-deoxy-delta9,12-PGD2)-glutathione
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_952c271c_abe8_49a2_be27_962315db3ab3
name: EXT1:EXT2
has part: Q16394
is encoded by: hsa:2132
is encoded by: hsa:2131
is: SBO:0000297
constant: true
initial concentration: NaN
type: Species
has only substance units: false
boundary condition: true
initial amount: NaN

metaR 3HLYTCL
modifier: MODEL1109130000#
is version of: ECO:0000269
fast: false
name: 3-Hydroxy-L-tyrosine carboxy-lyase
is version of: http://identifiers.org/ec-code/4.1.1.28
reactant: MODEL1109130000#
is: SBO:0000176
reversible: false
product: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: 1644.1 SUBSYSTEM: Tyrosine metabolism EC Number: 4.1.1.28 Confidence Level: 4 AUTHORS: NOTES: SAB

http://identifiers.org/biomodels.db/MODEL1109130000#_11929893_a3e3_43a3_8a64_967261b7c04f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ee2dd2b9_bbd1_4dd9_afc1_2769f0a670b7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6dca1cc9_6e91_4e18_8b8a_2370868ea612
value: 0.0
type: LocalParameter

metaR r1881
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
is described by: http://identifiers.org/pubmed/14770309
modifier: MODEL1109130000#
reactant: MODEL1109130000#
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
name: Y+LAT2 Utilized transport
fast: false
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_3b001a81_6978_4475_a3a3_5a419f906cce
initial amount: NaN
type: Species
initial concentration: NaN
has only substance units: false
is encoded by: hsa:2571
boundary condition: true
is: Q8IVA8
constant: false
is: SBO:0000252
name: GAD1

metaR LNLNCGCPT1
type: Reaction
notes: GENE_ASSOCIATION: (1375.1) or (1375.3) or (1375.4) or (126129.1) or (1374.1) or (1375.2) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: NOTES: NJ
name: carnitine O-palmitoyltransferase
fast: false
modifier: MODEL1109130000#
reactant: MODEL1109130000#
reversible: false
is version of: http://identifiers.org/ec-code/2.3.1.21
product: MODEL1109130000#
is: SBO:0000176
is version of: ECO:0000269

metaR ENMAN3g
type: Reaction
is described by: http://identifiers.org/pubmed/11007802
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12770767
notes: GENE_ASSOCIATION: SUBSYSTEM: N-glycan synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:11007802,PMID:12770767 NOTES: NCD
is: SBO:0000176
fast: false
reversible: false
is version of: ECO:0000000
product: MODEL1109130000#
name: Endomannosidase (glc3man-producing), Golgi apparatus

http://identifiers.org/biomodels.db/MODEL1109130000#_39423c63_ed4e_41bd_9691_706405c577c4
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3a7a7ff0_3864_4fb6_aabd_4a4705c42e99
value: 0.0
type: LocalParameter

metaR DOPAt4 2 r
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12719981
notes: GENE_ASSOCIATION: (6530.1) or (6531.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:12719981 NOTES: SAB
is: SBO:0000185
reactant: MODEL1109130000#
product: MODEL1109130000#
fast: false
type: Reaction
name: Dopamine reversible transport in via sodium symport (1:2)
is version of: ECO:0000269
reversible: true

metaM CE4825 x
notes: FORMULA: C45H66N7O18P3S CHARGE: -4 INCHI: InChI=1/C45H70N7O18P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-33(53)28-36(55)74-27-26-47-35(54)24-25-48-43(58)40(57)45(2,3)30-67-73(64,65)70-72(62,63)66-29-34-39(69-71(59,60)61)38(56)44(68-34)52-32-51-37-41(46)49-31-50-42(37)52/h5-6,8-9,11-12,14-15,17-18,20-21,31-34,38-40,44,53,56-57H,4,7,10,13,16,19,22-30H2,1-3H3,(H,47,54)(H,48,58)(H,62,63)(H,64,65)(H2,46,49,50)(H2,59,60,61)/p-4/b6-5-,9-8-,12-11-,15-14-,18-17-,21-20-/t33-,34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4825
boundary condition: false
has only substance units: false
type: Species
is: SBO:0000247
initial amount: NaN
initial concentration: 1.0
constant: false
name: (3S)-hydroxy-tetracosa-6,9,12,15,18,21-all-cis-hexaenoyl-CoA

http://identifiers.org/biomodels.db/MODEL1109130000#_96cd6646_4044_41fe_ab4e_8b16039273eb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_12566539_5b44_4ee9_bde4_30cbc9692344
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5c3a9cd9_374b_4026_8d3a_470ccd675d4d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c6ebbd73_e48e_4ed7_9885_3de6ca51c727
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_94971cad_2630_4421_9f48_8f14f050a3c7
units: dimensionless
value: 0.0
type: LocalParameter

metaR r1886
type: Reaction
is described by: http://identifiers.org/pubmed/14770309
name: Y+LAT2 Utilized transport
reactant: MODEL1109130000#
fast: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770310
reversible: false
product: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000185

metaR LNLNCGCPT2
fast: false
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.21
name: carnitine transferase
type: Reaction
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 1376.1 SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.21 Confidence Level: 4 AUTHORS: NOTES: NJ
modifier: MODEL1109130000#
is version of: ECO:0000269
reversible: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#f9ce2f9c_ca90_4418_bbe9_35b4b3bc1186
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eccf2c5c_b6dc_44ab_98ac_fa3dd90eb94d
value: 0.0
type: LocalParameter

metaR S23T4g
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8288606
is described by: http://identifiers.org/pubmed/10504389
is described by: http://identifiers.org/pubmed/8920913
is described by: http://identifiers.org/pubmed/8027041
is: SBO:0000176
fast: false
reactant: MODEL1109130000#
name: beta-galactoside alpha-2,3-sialyltransferase
is version of: http://identifiers.org/ec-code/2.4.99.4
notes: GENE_ASSOCIATION: (6484.1) or (6482.1) or (6483.1) or (6482.2) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.99.4 Confidence Level: 4 AUTHORS: PMID:10504389,PMID:7901202,PMID:8027041,PMID:8288606,PMID:8920913 NOTES: NCD
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7901202
reversible: false
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_ceba6b06_15dc_401a_a50d_ceca0fb41d1e
boundary condition: true
has only substance units: false
name: PGM1
constant: false
initial concentration: NaN
initial amount: NaN
is encoded by: hsa:5236
is: B4DPV0
type: Species
is: SBO:0000252

metaR MI1PS
modifier: MODEL1109130000#
reactant: MODEL1109130000#
name: myo-Inositol-1-phosphate synthase
is version of: ECO:0000269
notes: GENE_ASSOCIATION: 51477.1 SUBSYSTEM: Inositol phosphate metabolism EC Number: 5.5.1.4 Confidence Level: 4 AUTHORS: PMID:12941308 NOTES: NCD
is: SBO:0000176
type: Reaction
fast: false
is version of: http://identifiers.org/ec-code/5.5.1.4
is described by: http://identifiers.org/pubmed/12941308
product: MODEL1109130000#
reversible: false

metaR ESTRIOLtr
is: SBO:0000185
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 2 AUTHORS: NOTES: specific mechanism not known, proton dependence for trans-mit transport has been suggested, however directionality and stoichiometry has not yet been elucidated. see PMID: 12770731 and others NJ
name: estriol intracellular transport
reactant: MODEL1109130000#
fast: false
product: MODEL1109130000#
reversible: true
is version of: ECO:0000000
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_84693535_13c3_491b_a48c_8edb9979f31f
is encoded by: hsa:10400
constant: true
has only substance units: false
initial amount: NaN
name: PEMT
type: Species
initial concentration: NaN
is: Q9UBM1
is: SBO:0000252
boundary condition: true

metaR r1887
name: Y+LAT2 Utilized transport
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000185
product: MODEL1109130000#
fast: false
type: Reaction
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770310
reversible: false
is described by: http://identifiers.org/pubmed/14770309

metaR FAOXC161C141m
reactant: MODEL1109130000#
name: fatty acid beta oxidation(C16:1-->C14:1)m
reversible: false
fast: false
type: Reaction
modifier: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/20195903
is: SBO:0000176
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID:20195903, PMID:20490924, international journal of molecular medicine 19: 81-87, 2007. EC Number: NOTES: mitochondrial beta oxidation GENE_ASSOCIATION: (37.1 and 3030.1 and 3032.1)
is described by: http://identifiers.org/pubmed/20490924

metaM CE4842 r
name: trans,cis,cis-2,11,14-eicosatrienoyl-CoA
constant: false
boundary condition: false
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C41H64N7O17P3S CHARGE: -4 INCHI: InChI=1/C41H68N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-32(50)69-25-24-43-31(49)22-23-44-39(53)36(52)41(2,3)27-62-68(59,60)65-67(57,58)61-26-30-35(64-66(54,55)56)34(51)40(63-30)48-29-47-33-37(42)45-28-46-38(33)48/h8-9,11-12,20-21,28-30,34-36,40,51-52H,4-7,10,13-19,22-27H2,1-3H3,(H,43,49)(H,44,53)(H,57,58)(H,59,60)(H2,42,45,46)(H2,54,55,56)/p-4/b9-8-,12-11-,21-20+/t30-,34+,35+,36u,40-/m0/s1 EHMN_ABBREVIATION: CE4842
has only substance units: false
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#b76b6226_2e22_4f14_bcee_3cf66f35616b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17ccb37d_8af6_4224_82e5_5abd2b91c735
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3861664c_a3fb_4e42_8234_2c1fa0bd38e4
value: 0.0
type: LocalParameter

metaR RE2030M
is described by: http://identifiers.org/pubmed/12594532
is version of: http://identifiers.org/ec-code/2.3.1.1
modifier: MODEL1109130000#
product: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/12459178
is: SBO:0000176
notes: GENE_ASSOCIATION: 162417.1 SUBSYSTEM: Methionine and cysteine metabolism EC Number: 2.3.1.1 Confidence Level: 0 AUTHORS: PMID:12459178,PMID:12594532 NOTES:
reversible: true
name: RE2030
type: Reaction
reactant: MODEL1109130000#

metaM ksi pre33 g
constant: false
notes: FORMULA: C233H372N16O197S10X CHARGE: -11 INCHI:
initial amount: NaN
type: Species
boundary condition: false
is: SBO:0000247
name: keratan sulfate I biosynthesis, precursor 33
has only substance units: false
initial concentration: 1.0

metaR r1884
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770309
is: SBO:0000185
type: Reaction
product: MODEL1109130000#
modifier: MODEL1109130000#
name: Y+LAT2 Utilized transport
is described by: http://identifiers.org/pubmed/14770310
fast: false
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_fcb7f32e_0aaf_40db_9d68_65f6fbbe03c9
constant: false
initial amount: NaN
name: AGA
type: Species
is: SBO:0000252
has only substance units: false
initial concentration: NaN
boundary condition: true
is: P20933
is encoded by: hsa:175

http://identifiers.org/biomodels.db/MODEL1109130000#a6724b48_0522_4e52_8554_3228aba0ba6e
value: 0.0
type: LocalParameter

metaR RE2680G
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 9331.1 SUBSYSTEM: Glycosphingolipid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11172001 NOTES:
fast: false
name: RE2680
reversible: false
type: Reaction
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11172001
reactant: MODEL1109130000#
is: SBO:0000176

metaR RE0924R
is described by: http://identifiers.org/pubmed/8070342
type: Reaction
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:3090812,PMID:7364927,PMID:8070342,PMID:9633995 NOTES:
is: SBO:0000176
modifier: MODEL1109130000#
fast: false
is described by: http://identifiers.org/pubmed/3090812
reactant: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/7364927
reversible: false
name: RE0924
is version of: http://identifiers.org/ec-code/2.4.1.17
is described by: http://identifiers.org/pubmed/9633995

metaR MI1PP
reactant: MODEL1109130000#
reversible: false
is: SBO:0000176
type: Reaction
is described by: http://identifiers.org/pubmed/9322233
is described by: http://identifiers.org/pubmed/2906139
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (3612.1) or (3613.1) SUBSYSTEM: Inositol phosphate metabolism EC Number: 3.1.3.25 Confidence Level: 4 AUTHORS: PMID:1377913,PMID:2906139,PMID:9322233 NOTES: JLR
is version of: http://identifiers.org/ec-code/3.1.3.25
name: myo-inositol 1-phosphatase
is version of: ECO:0000269
is described by: http://identifiers.org/pubmed/1377913
fast: false
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_587f3a16_581a_4f2c_9374_eac5ad7656ee
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7ac31336_cb1b_40e1_8efb_74a6674e6b57
units: dimensionless
value: 0.0
type: LocalParameter

metaM cholcoa x
initial amount: NaN
is: HMDB01374
notes: FORMULA: C45H70N7O20P3S CHARGE: -4 INCHI: InChI=1S/C45H74N7O20P3S/c1-23(26-7-8-27-34-28(18-31(55)45(26,27)5)44(4)12-10-25(53)16-24(44)17-29(34)54)6-9-33(57)76-15-14-47-32(56)11-13-48-41(60)38(59)43(2,3)20-69-75(66,67)72-74(64,65)68-19-30-37(71-73(61,62)63)36(58)42(70-30)52-22-51-35-39(46)49-21-50-40(35)52/h21-31,34,36-38,42,53-55,58-59H,6-20H2,1-5H3,(H,47,56)(H,48,60)(H,64,65)(H,66,67)(H2,46,49,50)(H2,61,62,63)/p-4/t23-,24+,25-,26-,27+,28+,29-,30-,31+,34+,36-,37-,38+,42-,44+,45-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00844 EHMN_ABBREVIATION: C01794
type: Species
initial concentration: 1.0
is: CHEBI:57373
boundary condition: false
has only substance units: false
constant: false
is: SBO:0000247
name: choloyl-CoA(4-)

http://identifiers.org/biomodels.db/MODEL1109130000#bbdc972e_91c1_4bf9_93d5_99dcb116e790
value: 1000.0
type: LocalParameter

metaM tdeACP c
initial amount: NaN
constant: false
notes: FORMULA: C25H45N2O8PRS CHARGE: -1 INCHI:
initial concentration: 1.0
has only substance units: false
is: SBO:0000247
boundary condition: false
name: cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#e2342076_11bb_47d8_b2f7_c4fe499d4c5c
value: -1000.0
type: LocalParameter

metaR r1885
is described by: http://identifiers.org/pubmed/14770310
fast: false
product: MODEL1109130000#
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
name: Y+LAT2 Utilized transport
is: SBO:0000185
reactant: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_1ef93117_9ba7_4991_a3f2_3f1491c040a5
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f0c0deab_73f3_45e7_aa71_3bac362a6431
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_34d48ea4_7092_45ae_9409_18efff29e032
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_883a86a1_2bf8_4e64_9d5b_4caaa8c82935
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4e964bac_bc34_4215_a6e6_49c5daa5f88d
value: 1000.0
type: LocalParameter

metaR r1879
fast: false
is described by: http://identifiers.org/pubmed/14770309
reversible: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185
product: MODEL1109130000#
modifier: MODEL1109130000#
reactant: MODEL1109130000#
type: Reaction
name: Y+LAT2 Utilized transport
is described by: http://identifiers.org/pubmed/14770310

http://identifiers.org/biomodels.db/MODEL1109130000#_2bc2caee_b8dd_4b8a_b546_22f4f39a6333
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5bf3e8a2_af79_4f05_8217_a3435afe0249
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cff54100_384f_4e6b_9aa3_973484e7e86d
value: 1000.0
type: LocalParameter

metaM CE2848 c
initial amount: NaN
type: Species
notes: FORMULA: C8H14NO10P CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE2848
boundary condition: false
is: SBO:0000247
has only substance units: false
initial concentration: 1.0
constant: false
name: fructoseglycine ketone 3-phosphate

http://identifiers.org/biomodels.db/MODEL1109130000#_40c4f04f_cc73_4045_ac14_e8598d1751ab
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_972de6a4_3531_4d48_9cc1_a7fb0c222b55
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d27fc107_9ed8_4d87_aa41_efca0b3f017a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_792cd4a8_2547_44cc_80b4_2db17152d2c0
units: dimensionless
value: 0.0
type: LocalParameter

metaR C4OHc
notes: SUBSYSTEM: Fatty acid oxidation Confidence Level: 4 AUTHORS: PMID: 17442642 EC Number: NOTES: GENE_ASSOCIATION: (1374.1 or 1375.1 or 126129.1)
modifier: MODEL1109130000#
name: production of 3-hydroxybytyryl carnitinec
type: Reaction
is: SBO:0000176
product: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/17442642
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1109130000#_79d23010_17ef_4d27_85a6_a308d1e2a1f5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_185e5f7b_f02d_4275_8dbd_847d7e03073a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_247804cc_8c1f_4e74_bbce_ed454e8328e8
value: 1000.0
type: LocalParameter

metaR T2M26DCOAHLx
name: trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (x)
reactant: MODEL1109130000#
product: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000176
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/4.2.1.17
type: Reaction
notes: GENE_ASSOCIATION: (1891.1) or (1962.1) SUBSYSTEM: Limonene and pinene degradation EC Number: 4.2.1.17 Confidence Level: 1 AUTHORS: NOTES: SAB
is version of: ECO:0000212

metaR RE1957G
notes: GENE_ASSOCIATION: (8395.1) or (23396.1) or (8394.1) SUBSYSTEM: Phosphatidylinositol phosphate metabolism EC Number: 2.7.1.68 Confidence Level: 0 AUTHORS: PMID:10231032,PMID:10358929,PMID:11493657,PMID:9211928 NOTES:
is described by: http://identifiers.org/pubmed/9211928
name: RE1957
reactant: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/10231032
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/10358929
fast: false
is: SBO:0000176
is described by: http://identifiers.org/pubmed/11493657
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.7.1.68

metaR 3DPHBH1
is: SBO:0000176
is version of: ECO:0000000
fast: false
is described by: http://identifiers.org/pubmed/11051212
product: MODEL1109130000#
type: Reaction
reversible: false
name: Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NADH)
notes: GENE_ASSOCIATION: SUBSYSTEM: Ubiquinone synthesis EC Number: Confidence Level: 2 AUTHORS: PMID:11051212 NOTES: Used to make Ubiquinone-10 enzyme has not been identified yet. IT
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_16c535ba_4909_4a91_bc9a_02ebbd4d72a9
value: -1000.0
type: LocalParameter

metaR r1877
is described by: http://identifiers.org/pubmed/14770309
name: Y+LAT2 Utilized transport
reactant: MODEL1109130000#
reversible: false
product: MODEL1109130000#
modifier: MODEL1109130000#
is: SBO:0000185
fast: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
type: Reaction
is described by: http://identifiers.org/pubmed/14770310

http://identifiers.org/biomodels.db/MODEL1109130000#ec0b075f_c0ab_44a4_83c1_6558697c81e4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f4cf04bf_e157_44b3_ac39_90b35d2e8df9
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G1:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#d252e60f_1130_4705_a5ce_6a511381f85b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_828bce9e_b07f_4e75_811f_68d3addf6c6e
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_72bf651e_ce9b_4f5c_9c19_31068c162366
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_d55450b0_f2d9_4310_8dd3_72b70cec254c
type: Species
initial amount: NaN
boundary condition: true
is encoded by: hsa:93979
has only substance units: false
initial concentration: NaN
constant: true
is: Q8WXQ8
is: SBO:0000252
name: CPA5

metaR 3DPHBH2
is described by: http://identifiers.org/pubmed/11051212
reversible: false
is: SBO:0000176
name: Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NADPH)
notes: GENE_ASSOCIATION: SUBSYSTEM: Ubiquinone synthesis EC Number: Confidence Level: 2 AUTHORS: PMID:11051212 NOTES: Used to make Ubiquinone-10 enzyme has not been identified yet. IT
fast: false
reactant: MODEL1109130000#
is version of: ECO:0000000
type: Reaction
product: MODEL1109130000#

metaR r1876
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
reactant: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#
type: Reaction
name: Y+LAT2 Utilized transport
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185
fast: false
is described by: http://identifiers.org/pubmed/14770309

http://identifiers.org/biomodels.db/MODEL1109130000#a7a3e076_f498_48aa_8099_b1aa934a2ea5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b8bc734c_0be6_407b_8cc0_0851763ebb4b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e050ed06_0ce3_4209_8ad7_eec741718c3a
value: 0.0
type: LocalParameter

metaR RE2680C
name: RE2680
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11172001
reversible: false
type: Reaction
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Glycosphingolipid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11172001 NOTES:
product: MODEL1109130000#
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1109130000#_3627649a_6197_414e_91eb_2757e8cafc85
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d4425455_26e6_4f46_9741_4a9ece462ad4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c4a7f726_9722_4f14_b019_0c7e8c5656ae
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8db8be36_39d5_40ee_8f9e_c5e0983879b3
value: 1000.0
type: LocalParameter

metaR GLGNS1
type: Reaction
reversible: false
is: SBO:0000176
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/15238248
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: (8908.1) and (2997.1) or (2998.1) and (2992.1) or (2997.1) and (2992.1) or (8908.1) and (2998.1) SUBSYSTEM: Starch and sucrose metabolism EC Number: 2.4.1.11 Confidence Level: 2 AUTHORS: PMID:15238248 NOTES: NCD
name: glycogen synthase (ggn -> glygn1)
fast: false
is version of: http://identifiers.org/ec-code/2.4.1.11
product: MODEL1109130000#
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_3e68c778_c3ee_4dd1_aa1b_539a3ac3aa07
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4ac4d17a_33b3_4f5d_b1c4_b958e6015673
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_954948f2_1124_4a7f_86ea_23ebcfc90e09
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1794b10f_6d94_4a8f_aa8c_f7b2af8b5d93
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_47d7644c_1b8a_4181_8a6b_6e6c6973b009
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e053587e_f001_4bab_b82a_c993328fb227
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6daa686f_4d30_4324_9959_dfd59eee9088
initial amount: NaN
name: TPO
is encoded by: hsa:7173
constant: false
has only substance units: false
initial concentration: NaN
boundary condition: true
type: Species
is: SBO:0000252

metaM cholcoa c
name: choloyl-CoA(4-)
initial amount: NaN
has only substance units: false
initial concentration: 1.0
is: CHEBI:57373
is: SBO:0000247
notes: FORMULA: C45H70N7O20P3S CHARGE: -4 INCHI: InChI=1S/C45H74N7O20P3S/c1-23(26-7-8-27-34-28(18-31(55)45(26,27)5)44(4)12-10-25(53)16-24(44)17-29(34)54)6-9-33(57)76-15-14-47-32(56)11-13-48-41(60)38(59)43(2,3)20-69-75(66,67)72-74(64,65)68-19-30-37(71-73(61,62)63)36(58)42(70-30)52-22-51-35-39(46)49-21-50-40(35)52/h21-31,34,36-38,42,53-55,58-59H,6-20H2,1-5H3,(H,47,56)(H,48,60)(H,64,65)(H,66,67)(H2,46,49,50)(H2,61,62,63)/p-4/t23-,24+,25-,26-,27+,28+,29-,30-,31+,34+,36-,37-,38+,42-,44+,45-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00844 EHMN_ABBREVIATION: C01794
is: HMDB01374
type: Species
constant: false
boundary condition: false

metaM mem2emgacpail hs r
type: Species
constant: false
initial concentration: 1.0
is: SBO:0000247
has only substance units: false
initial amount: NaN
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)
boundary condition: false
notes: FORMULA: C59H110N3O40P3FULLRCO2FULLR2CO2 CHARGE: 0 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#_17b9ac76_f9f0_4cd3_8965_e82ac41e04b6
name: IDH1
is: SBO:0000252
constant: false
is: O75874
initial amount: NaN
boundary condition: true
is encoded by: hsa:3417
notes: DRUGBANK_UNKNOWN: DB01727, DB03461
type: Species
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_7dfceae0_1e4d_4e20_b6b2_c9ac5f9d31cc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_318a4910_5e76_41a7_a3ea_abfb1738729a
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_97886ff0_61e9_4429_9dee_45e5f3ec42a9
value: -1000.0
type: LocalParameter

metaR RE3559M
is version of: http://identifiers.org/ec-code/2.3.1.16
reactant: MODEL1109130000#
name: RE3559
modifier: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12054595
is: SBO:0000176
reversible: true
type: Reaction
fast: false
notes: GENE_ASSOCIATION: (10449.1) or (3032.1) or (3030.1) SUBSYSTEM: Eicosanoid metabolism EC Number: 2.3.1.16 Confidence Level: 0 AUTHORS: PMID:12054595 NOTES:

metaM HC00591 c
initial amount: NaN
initial concentration: 1.0
notes: FORMULA: C5H6NO4 CHARGE: -1 INCHI: InChI=1S/C5H7NO4/c6-4(8)2-1-3(7)5(9)10/h1-2H2,(H2,6,8)(H,9,10)/p-1 EHMN_ABBREVIATION: C00940
boundary condition: false
has only substance units: false
constant: false
type: Species
is: CHEBI:16769
is: SBO:0000247
name: 2-oxoglutaramate

http://identifiers.org/biomodels.db/MODEL1109130000#a0a60199_fdc6_46ca_bc2e_73e278f833bf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e2511a1c_0da1_461e_bd07_f59e50da2a99
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be4f8980_b346_4af4_ba32_57cc70a08954
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#be5f9484_ace8_491a_912d_a6b86f72acb0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bca2e092_368f_4010_9bd0_da5f19ee7837
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_a7ea24eb_e7aa_437c_9120_6c72b8310c12
initial concentration: NaN
type: Species
has only substance units: false
is: SBO:0000252
initial amount: NaN
constant: false
boundary condition: true
is: Q8N1Q1
is encoded by: hsa:377677
name: CA13

metaM CE5272 c
initial concentration: 1.0
constant: false
is: SBO:0000247
boundary condition: false
notes: FORMULA: C12H13N2O5S CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5272
initial amount: NaN
type: Species
has only substance units: false
name: 3,4-dihydro-1,4-benzothiazine-3-carboxylate

http://identifiers.org/biomodels.db/MODEL1109130000#a4a8e5c3_df92_4e20_b6b2_c40288099ae3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_04831e09_9a0c_42cd_a80e_20b9fb762281
is: SBO:0000252
constant: false
boundary condition: true
is: O95479
name: H6PD
initial concentration: NaN
is encoded by: hsa:9563
notes: DRUGBANK_UNKNOWN: DB00157
has only substance units: false
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_08416bc3_cbe3_4ba0_801c_4f6912853a9f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_661370cc_1e34_4dbd_a4e7_d7bf0d1df1fc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2790c73d_d541_4b35_ba66_bde76a0da50a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b1916f46_017d_4a4a_baef_e7e96cdbb6e2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8605aed2_0fc5_467e_9e67_c30d8141aed0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_30fb41bd_dc64_4f40_b2b8_8d12a17f268a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3aceffbd_8eff_45c4_9a59_829f47934cdc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7b9c2359_82c0_450f_b5f4_d9a80bcab2ab
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_21bb0993_90d0_4a1f_807a_bddcd3492de9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_54466477_8c56_4d3f_bd77_328eebc7727b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2a60f5ba_49f6_4cc6_ad58_f643d095d24b
boundary condition: true
is: SBO:0000252
constant: true
initial concentration: NaN
is encoded by: hsa:5140
initial amount: NaN
type: Species
is: A7E2E5
name: PDE3B
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_001d1d68_6c2b_4dcf_9909_dd77efacd6c1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0ad42b60_8c32_4dd9_9159_042dc4d1244f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ec947b0f_910e_4781_ad49_9c1024df1a99
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_248e8232_ee6e_4984_8921_c79c601164ee
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_1fc280e8_9a3a_48de_b462_bd80d8326188
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f89b859_193c_4004_998f_aa0c8479192a
has only substance units: false
initial concentration: NaN
boundary condition: true
is: E9PEN2
is encoded by: hsa:11320
constant: false
name: MGAT4A
type: Species
is: SBO:0000252
initial amount: NaN

metaR r2141
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11076396
type: Reaction
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14579113
is: SBO:0000185
is described by: http://identifiers.org/pubmed/11076394
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
fast: false
reversible: true
modifier: MODEL1109130000#

metaR r2142
is: SBO:0000185
reversible: true
product: MODEL1109130000#
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
fast: false
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
type: Reaction
is described by: http://identifiers.org/pubmed/11076394
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_2f28ca2c_f451_4884_9602_62b4c6d5dc05
value: 1000.0
type: LocalParameter

metaM CE5151 c
name: 11-cis-eicosenoyl-CoA
is: SBO:0000247
initial amount: NaN
notes: FORMULA: C41H68N7O17P3S CHARGE: -4 INCHI: EHMN_ABBREVIATION: CE5151
constant: false
type: Species
boundary condition: false
has only substance units: false
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_09a00a54_b5d4_4c32_acd3_24907de0c991
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2581c5d3_f355_481c_b858_0552e224fd34
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d74bbc3e_bf69_43b2_bb5b_5c554e01d5d2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_10bcf088_1cd6_4553_8dd5_f45009ed7364
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_774c0fed_f8c1_4229_b32b_7cbedeeaaa02
is: SBO:0000252
initial concentration: NaN
name: B3GAT1
initial amount: NaN
has only substance units: false
type: Species
boundary condition: true
is encoded by: hsa:27087
constant: true

http://identifiers.org/biomodels.db/MODEL1109130000#_710897a0_58be_4110_bfda_2c5bf21c9186
value: 0.0
type: LocalParameter

metaM pail35p hs r
boundary condition: false
name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-)
initial concentration: 1.0
is: SBO:0000247
notes: FORMULA: C9H14O15P3FULLRCO2FULLR2CO2 CHARGE: -5 INCHI:
has only substance units: false
initial amount: NaN
constant: false
is: CHEBI:57923
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_5b5072a0_1e12_49f0_ae65_5a50f668f040
constant: true
boundary condition: true
is encoded by: hsa:1553
initial amount: NaN
has only substance units: false
type: Species
is: Q16696
initial concentration: NaN
is: SBO:0000252
name: CYP2A13

http://identifiers.org/biomodels.db/MODEL1109130000#fc165761_d648_4e82_a908_ad6c2d0ce46c
value: 1000.0
type: LocalParameter

metaR r2140
is: SBO:0000185
reversible: true
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11076396
type: Reaction
fast: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14579113
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:
is described by: http://identifiers.org/pubmed/11076394
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14

http://identifiers.org/biomodels.db/MODEL1109130000#_0325a8d1_fb65_49af_b01b_67f70c550c7e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_89dc04d0_3f66_4856_8e62_c062ce4235af
units: dimensionless
value: 0.0
type: LocalParameter

metaR TAXOLte
reversible: true
reactant: MODEL1109130000#
is: SBO:0000185
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: NOTES: unknown mechanism, related cyp P450 metabolism reactions NJ
fast: false
type: Reaction
product: MODEL1109130000#
name: xenobiotic transport
is version of: ECO:0000000

http://identifiers.org/biomodels.db/MODEL1109130000#_775dd547_09f1_456d_9616_25ff496bb9ce
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b24fb5e1_9801_4587_9e34_326ad03a12c2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c1d644f2_4308_468f_92a8_1ef92b0895bc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3afab1f6_98a9_49d1_9dd9_96b99c9d1702
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dcffde78_d345_4451_b0b1_4dc82bc0a643
value: 0.0
type: LocalParameter

metaM 2hexdtetcoa x
type: Species
initial concentration: 1.0
initial amount: NaN
notes: FORMULA: C37H54N7O17P3S CHARGE: -4
boundary condition: false
constant: false
is: SBO:0000247
name: 2,7,10,13-hexadecatetraenoylcoa
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_8a1593c3_7220_456c_b401_bcf78922abfc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_736e32af_97b8_43fc_85ca_b350ab017a04
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ee3ee072_edd7_4a17_9fa6_3dcfbdbbe160
units: dimensionless
value: 0.0
type: LocalParameter

metaM lpam m
is: SBO:0000247
initial concentration: 1.0
initial amount: NaN
is: HMDB00962
type: Species
constant: false
has only substance units: false
name: lipoamide
is: CHEBI:17460
boundary condition: false
notes: FORMULA: C8H15NOS2 CHARGE: 0 INCHI: InChI=1S/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10) HEPATONET_1.0_ABBREVIATION: HC00225 EHMN_ABBREVIATION: C00248

http://identifiers.org/biomodels.db/MODEL1109130000#_698233a9_bcb2_49e5_9010_bb69dc8b2ee3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_942b803c_f1ed_45ad_a628_a36d04af2b36
value: 0.0
type: LocalParameter

metaR RE3020R
fast: false
type: Reaction
is: SBO:0000176
is described by: http://identifiers.org/pubmed/11368003
name: RE3020
is version of: http://identifiers.org/ec-code/1.14.13.30
reversible: false
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9799565
is described by: http://identifiers.org/pubmed/9862787
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (8529.1) or (4051.1) or (126410.1) SUBSYSTEM: Eicosanoid metabolism EC Number: 1.14.13.30 Confidence Level: 0 AUTHORS: PMID:11368003,PMID:9799565,PMID:9862787 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_23554c93_4427_41d2_a7e0_ddafdf5a8bfb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_557c616d_97b2_426c_abc7_ebce12b66d29
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5dbde188_ea16_46fa_a1be_91d7459dc8ea
value: 1000.0
type: LocalParameter

metaR RE3225R
type: Reaction
product: MODEL1109130000#
modifier: MODEL1109130000#
name: RE3225
is described by: http://identifiers.org/pubmed/10970790
fast: false
reversible: false
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 64834.1 SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
is: SBO:0000176

metaR EX dgchol LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Chenodeoxyglycocholate exchange
type: Reaction

metaR G14T16g
product: MODEL1109130000#
reversible: false
modifier: MODEL1109130000#
fast: false
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.4.1.38
is described by: http://identifiers.org/pubmed/1903938
is described by: http://identifiers.org/pubmed/9435216
name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi
is described by: http://identifiers.org/pubmed/3094506
is described by: http://identifiers.org/pubmed/9405390
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/3144273
type: Reaction
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: (8703.1) or (2683.1) or (8704.2) or (8704.1) or (9334.1) SUBSYSTEM: Keratan sulfate synthesis EC Number: 2.4.1.38 Confidence Level: 4 AUTHORS: PMID:12512857,PMID:1903938,PMID:3094506,PMID:3144273,PMID:9405390,PMID:9435216 NOTES: Keratan sulfate I biosynthesis NCD
is described by: http://identifiers.org/pubmed/12512857

metaR r2144
reversible: true
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
type: Reaction
fast: false
is described by: http://identifiers.org/pubmed/11076394
modifier: MODEL1109130000#
reactant: MODEL1109130000#
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
is: SBO:0000185
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#_00939dea_811d_4211_ad6c_f0c72b8e15a0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dc927dbf_3624_4041_86db_7bcaae3b90aa
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_18acc524_a6ae_4ca1_a8e5_720b512dac39
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8603a482_c212_4d64_bd86_3f8acae5935b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5d1877b2_99c3_4bb4_9955_d83d13a3cd88
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_08c4e57d_8542_4ad1_aeb4_730afd2ca828
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a69c1fe6_ddda_4357_9cb8_431c14d82a43
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_667b0635_0736_4040_a2dd_651a85b1dc75
value: 1000.0
type: LocalParameter

metaM cholcoa m
boundary condition: false
initial concentration: 1.0
notes: FORMULA: C45H70N7O20P3S CHARGE: -4 INCHI: InChI=1S/C45H74N7O20P3S/c1-23(26-7-8-27-34-28(18-31(55)45(26,27)5)44(4)12-10-25(53)16-24(44)17-29(34)54)6-9-33(57)76-15-14-47-32(56)11-13-48-41(60)38(59)43(2,3)20-69-75(66,67)72-74(64,65)68-19-30-37(71-73(61,62)63)36(58)42(70-30)52-22-51-35-39(46)49-21-50-40(35)52/h21-31,34,36-38,42,53-55,58-59H,6-20H2,1-5H3,(H,47,56)(H,48,60)(H,64,65)(H,66,67)(H2,46,49,50)(H2,61,62,63)/p-4/t23-,24+,25-,26-,27+,28+,29-,30-,31+,34+,36-,37-,38+,42-,44+,45-/m1/s1 HEPATONET_1.0_ABBREVIATION: HC00844 EHMN_ABBREVIATION: C01794
is: CHEBI:57373
is: SBO:0000247
name: choloyl-CoA(4-)
has only substance units: false
type: Species
initial amount: NaN
is: HMDB01374
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#e5e702a1_9b56_40a6_8d9e_baf4da6245cd
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_f6712962_8da8_49b2_b55e_ef97ed3a3273
initial amount: NaN
initial concentration: NaN
is: SBO:0000252
boundary condition: true
type: Species
constant: true
name: null
has only substance units: false
is encoded by: hsa:AA629629

metaR r2143
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:
is: SBO:0000185
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
type: Reaction
is described by: http://identifiers.org/pubmed/11076394
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
reactant: MODEL1109130000#
modifier: MODEL1109130000#
reversible: true
product: MODEL1109130000#
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_81fe4ea5_c8aa_4159_ab20_4288b203ca70
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a0e2c52_8fb3_4fc2_a643_59a097c7333e
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_98e8f7c7_5a7a_45d2_b254_d2718620b340
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d545e394_bef2_4a13_9531_1fbdfd311b28
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c7e7e346_ab1e_44d6_8b0d_e4871a8d6f5d
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_80be84dc_c37a_4418_b310_e718a57a3c7e
value: 0.0
type: LocalParameter

metaR GLB1
fast: false
is described by: http://identifiers.org/pubmed/9054950
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/3143362
notes: GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) or (5476.1) and (2720.1) SUBSYSTEM: Sphingolipid metabolism EC Number: 3.2.1.23 Confidence Level: 4 AUTHORS: PMID:11550799,PMID:1755850,PMID:1794986,PMID:1953646,PMID:2111707,PMID:3143362,PMID:39554,PMID:7213753,PMID:7575473,PMID:8985184,PMID:9020182,PMID:9054950 NOTES: NJ
type: Reaction
product: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/1794986
is described by: http://identifiers.org/pubmed/8985184
is described by: http://identifiers.org/pubmed/11550799
is version of: http://identifiers.org/ec-code/3.2.1.23
reversible: false
is described by: http://identifiers.org/pubmed/39554
is described by: http://identifiers.org/pubmed/1755850
name: Beta-galactosidase
is described by: http://identifiers.org/pubmed/2111707
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9020182
is version of: ECO:0000000
is described by: http://identifiers.org/pubmed/1953646
is described by: http://identifiers.org/pubmed/7575473
is described by: http://identifiers.org/pubmed/7213753

metaM acglu m
initial amount: NaN
name: N-acetyl-L-glutamate(2-)
is: CHEBI:44337
type: Species
notes: FORMULA: C7H9NO5 CHARGE: -2 INCHI: InChI=1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/p-2/t5-/m0/s1 EHMN_ABBREVIATION: C00624
boundary condition: false
initial concentration: 1.0
is: HMDB01138
is: SBO:0000247
has only substance units: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_13ee56e9_fbdc_405e_a53e_d22477d251f8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_cb2f6b34_1a01_49f3_abf7_f4d43187ff9c
has only substance units: false
name: RPIA
is: SBO:0000252
is encoded by: hsa:22934
is: P49247
type: Species
boundary condition: true
initial amount: NaN
initial concentration: NaN
constant: true

metaR GTHRDtr
reactant: MODEL1109130000#
name: glutathione transport via diffusion
product: MODEL1109130000#
fast: false
reversible: true
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, endoplasmic reticular EC Number: Confidence Level: 1 AUTHORS: NOTES: unknown mechanism - NJ
type: Reaction
is version of: ECO:0000000
is: SBO:0000185

http://identifiers.org/biomodels.db/MODEL1109130000#_3fdf0e07_fceb_475c_be74_579389606c74
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d5da4af8_9547_4fe5_b6bc_e8f73a33327b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f0a07c07_ce13_418d_948b_c7efa2736a20
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B1:ATP6V1C1:ATP6V1E1:ATP6V1G2:ATP6V1F
type: Species

metaM CE6243 c
initial amount: NaN
type: Species
initial concentration: 1.0
boundary condition: false
is: SBO:0000247
constant: false
notes: FORMULA: C30H45N3O10S CHARGE: -2 INCHI: EHMN_ABBREVIATION: CE6243
has only substance units: false
name: S-(9-deoxy-delta9,12-PGD2)-glutathione

http://identifiers.org/biomodels.db/MODEL1109130000#eddd21bc_1e08_499a_840d_a9f94ea0d347
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c8879230_2d4d_46ce_b8b4_e230ac691e37
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_40767fa0_6dee_4cad_afc0_6b0d08dfbe5b
value: 1000.0
type: LocalParameter

metaR r2146
product: MODEL1109130000#
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
type: Reaction
is described by: http://identifiers.org/pubmed/11076394
is: SBO:0000185
modifier: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:
reactant: MODEL1109130000#
fast: false

metaR RAtn3
is described by: http://identifiers.org/pubmed/1503811
reversible: true
fast: false
name: 13-cis-retinoic acid transport, nuclear
type: Reaction
reactant: MODEL1109130000#
is: SBO:0000185
product: MODEL1109130000#
is version of: ECO:0000000
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, nuclear EC Number: Confidence Level: 2 AUTHORS: PMID:1503811 NOTES: IT

http://identifiers.org/biomodels.db/MODEL1109130000#b1c773ce_5608_4885_868c_817c1f22f516
value: 1000.0
type: LocalParameter

metaM Sfglutth c
has only substance units: false
is: CHEBI:57688
constant: false
is: HMDB01550
type: Species
boundary condition: false
name: S-formylglutathionate(1-)
is: SBO:0000247
notes: FORMULA: C11H16N3O7S CHARGE: -1 INCHI: InChI=1S/C11H17N3O7S/c12-6(11(20)21)1-2-8(16)14-7(4-22-5-15)10(19)13-3-9(17)18/h5-7H,1-4,12H2,(H,13,19)(H,14,16)(H,17,18)(H,20,21)/p-1/t6-,7-/m0/s1 EHMN_ABBREVIATION: C01031
initial concentration: 1.0
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#e82673de_82aa_4f55_afbc_3179a36b7011
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_beef27da_c7e4_46ba_9c68_92f66e9aed74
initial amount: NaN
is: SBO:0000252
constant: false
boundary condition: true
name: PYGL
type: Species
is encoded by: hsa:5836
initial concentration: NaN
has only substance units: false
is: P06737

http://identifiers.org/biomodels.db/MODEL1109130000#dfe76427_5d6d_4f0a_ab72_69c62cf57196
units: dimensionless
value: 0.0
type: LocalParameter

metaR SPTix
is version of: ECO:0000269
product: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.6.1.44
is: SBO:0000176
reactant: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/9783918
modifier: MODEL1109130000#
fast: false
name: serine-pyruvate aminotransferase (irreversible), peroxisomal
reversible: false
is described by: http://identifiers.org/pubmed/10960483
notes: GENE_ASSOCIATION: 189.1 SUBSYSTEM: Glycine, serine, alanine and threonine metabolism EC Number: 2.6.1.44 Confidence Level: 4 AUTHORS: PMID:10960483,PMID:9783918 NOTES:

metaR EX tcynt LPAREN e RPAREN
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Exchange/demand reaction EC Number: Confidence Level: 1 AUTHORS: NOTES:
is version of: ECO:0000000
is: SBO:0000185
fast: false
reversible: true
name: Thiocyanate exchange
type: Reaction

metaR r2145
is: SBO:0000185
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:
reactant: MODEL1109130000#
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
type: Reaction
is described by: http://identifiers.org/pubmed/11076394
fast: false
reversible: true
modifier: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_4bfabc86_ca66_4f3d_9e88_8635ba1cf7c2
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_701d45cd_3307_41dd_96fc_9b3454d041cf
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5132d5cb_bfc1_4f36_883e_30e2e6244178
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_77e65016_4115_4164_bfe4_118276cf2f7e
initial concentration: NaN
type: Species
is encoded by: hsa:AA203143
boundary condition: true
initial amount: NaN
constant: false
name: _AA203143_1_c
is: SBO:0000252
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_90a4ced7_0b5e_473f_af4b_97a58a7d0a8b
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7ae2bf30_a198_4562_a53c_7c43f75298ed
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_120cd14b_704e_4cfe_acb5_e2ab7e4f2c57
value: 1000.0
type: LocalParameter

metaR RE3559X
is version of: http://identifiers.org/ec-code/2.3.1.16
type: Reaction
product: MODEL1109130000#
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/12054595
modifier: MODEL1109130000#
is: SBO:0000176
reversible: true
fast: false
notes: GENE_ASSOCIATION: 30.1 SUBSYSTEM: Eicosanoid metabolism EC Number: 2.3.1.16 Confidence Level: 0 AUTHORS: PMID:12054595 NOTES:
name: RE3559

http://identifiers.org/biomodels.db/MODEL1109130000#_78999184_3394_43cc_b6cc_d6140c98f5bc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_296f9894_8313_4b2f_b260_cd6756c277d2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4373cbc3_a234_4597_9a78_23a985d0cb23
value: 0.0
type: LocalParameter

metaR r2148
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
product: MODEL1109130000#
type: Reaction
is described by: http://identifiers.org/pubmed/11076394
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
is: SBO:0000185
reactant: MODEL1109130000#
reversible: true
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:
fast: false
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#e3be68b6_88a8_4058_b89d_45ceb1d748fc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3b17e224_e995_4ef5_80cb_6cdf2195296d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ed7bafdc_591a_4b16_9c7e_5cbb41a64065
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a60b061f_a8f9_49e0_a462_86a441aa98fc
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP6V1D:ATP6V1H:ATP6V1A:ATP6V1B2:ATP6V1C1:ATP6V1E1:ATP6V1F:ATP6V1G1
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_9bd107dd_7c42_41e8_b7f8_5027369cf6ab
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eed1534b_e77d_4881_8560_35f532e76cb4
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE0925C
name: RE0925
product: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/9633995
is described by: http://identifiers.org/pubmed/8070342
reactant: MODEL1109130000#
type: Reaction
is version of: http://identifiers.org/ec-code/2.4.1.17
notes: GENE_ASSOCIATION: 54658.1 SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:2229315,PMID:8070342,PMID:9633995 NOTES:
is: SBO:0000176
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/2229315
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#e528e236_af60_4a23_aef5_8f56d5bb8478
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6b4050c9_1a8b_40f1_8a68_81e99be132f1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a6c7fca6_f634_49fb_9a10_851f73f12d57
value: 1000.0
type: LocalParameter

metaR r2147
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14579113
is described by: http://identifiers.org/pubmed/11076396
name: Resistance-Nodulation-Cell Division (RND) TCDB:2.A.60.1.14
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/11076394
reversible: true
reactant: MODEL1109130000#
is: SBO:0000185
product: MODEL1109130000#
notes: GENE_ASSOCIATION: 11136.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:11076394,PMID:11076396,PMID:14579113 NOTES:

http://identifiers.org/biomodels.db/MODEL1109130000#ae6f1256_5d69_4819_870f_3e23d56bbedc
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5f7b71c9_24e7_449d_9f30_fae7ff43a9dd
value: 0.0
type: LocalParameter

metaR METLEUex
notes: GENE_ASSOCIATION: (6520.1 and 8140.1) SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 4 AUTHORS: PMID:14770310 NOTES: SAB see PMID 14770310
is: SBO:0000185
is described by: http://identifiers.org/pubmed/14770310
is version of: ECO:0000269
reversible: false
name: Methionine/Leucine exchange (Met in)
fast: false
type: Reaction
modifier: MODEL1109130000#
reactant: MODEL1109130000#
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_4976db29_1b36_4a7d_92bd_b2ab2a8abcc3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_69ea8327_f63d_4077_8c65_72ef1e81dd42
value: 0.0
type: LocalParameter

metaM gm2a hs g
constant: false
name: GM2alpha
is: SBO:0000247
initial concentration: 1.0
initial amount: NaN
boundary condition: false
has only substance units: false
type: Species
notes: FORMULA: C49H85N3O25FULLRCO CHARGE: -1 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#_0b501cb6_0985_437d_beb0_fa01954faf7a
units: dimensionless
value: 0.0
type: LocalParameter

metaM ch4s c
has only substance units: false
boundary condition: false
is: SBO:0000247
initial amount: NaN
notes: FORMULA: CH4S CHARGE: 0 INCHI: InChI=1S/CH4S/c1-2/h2H,1H3 EHMN_ABBREVIATION: C00409
is: CHEBI:16007
name: Methanethiol
initial concentration: 1.0
constant: false
type: Species
is: HMDB03227

http://identifiers.org/biomodels.db/MODEL1109130000#_0a662bc0_736c_46b0_978d_dc8050358057
has only substance units: false
initial concentration: NaN
is: P42765
constant: false
is encoded by: hsa:10449
initial amount: NaN
boundary condition: true
type: Species
name: ACAA2
is: SBO:0000252

metaR NRVNCt
is: SBO:0000185
name: fatty acid transport via diffusion
is described by: http://identifiers.org/pubmed/12864740
reactant: MODEL1109130000#
product: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 2 AUTHORS: PMID:11788354,PMID:12864740 NOTES: NJ
fast: false
is version of: ECO:0000000
reversible: true
is described by: http://identifiers.org/pubmed/11788354
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_6ad8a1cf_8d52_47d9_bfa5_59e30d74542e
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6a399a2b_7fe1_448c_bc5a_41547cd8feec
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3f1c843c_18f5_4294_bc69_1df3a6af287c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7e20b2a6_82a1_4d3f_8971_c9c3a4deb1dc
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a523e2f8_e63d_4c9e_b7c4_6a5a913e06dc
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#fb60a710_9679_4ff2_a120_d55c376aff42
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_68e15a98_c656_403e_b409_4ac076ec8fe0
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_28b9ff56_48f8_4e23_b3ad_5770dd164c09
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4ecb8849_9b38_40c7_9aa5_ecd267d1553d
boundary condition: true
initial amount: NaN
is: SBO:0000297
has part: P09110
has part: Q15067
has part: P51659
constant: true
is encoded by: hsa:3295
is encoded by: hsa:51
name: ACAA1:HSD17B4:ACOX1
type: Species
is encoded by: hsa:30
has only substance units: false
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#c77e6db1_1a42_4b89_8a61_88270a923793
value: 1000.0
type: LocalParameter

metaM C02470 e
is: http://identifiers.org/pubchem.substance/5485
notes: FORMULA: C10H6NO4 CHARGE: -1 INCHI: InChI=1/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15) HEPATONET_1.0_ABBREVIATION: HC00945 EHMN_ABBREVIATION: C02470
boundary condition: false
is: C02470
constant: false
is: HMDB00881
initial concentration: 1.0
has only substance units: false
type: Species
initial amount: NaN
name: Xanthurenic acid
is: SBO:0000247

http://identifiers.org/biomodels.db/MODEL1109130000#d6ff0e95_2ee7_4fc6_ba3c_e2c507a56ffb
units: dimensionless
value: 0.0
type: LocalParameter

metaM g1m7masnC g
boundary condition: false
initial concentration: 1.0
constant: false
has only substance units: false
initial amount: NaN
is: SBO:0000247
type: Species
notes: FORMULA: C70H117N2O55X CHARGE: 0
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)

http://identifiers.org/biomodels.db/MODEL1109130000#ee2d174a_acb5_4f99_94d4_a5d8a561c381
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ef61c136_0875_4092_b79b_2ecea5317ccc
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b9ed7957_1eba_4509_867c_54defc5143f8
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: PIGP:PIGA:PIGC:PIGH:DPM2:PIGQ
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#b2f215b1_c0fe_4eff_83a9_80141687b791
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_44ebb2e0_05e6_4640_bb0b_12d17ec53edf
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bf4c2302_abf5_4f52_9505_a9cb09184fc8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f75eefe1_5040_4d04_8ad2_c0c8a8861d03
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_630f30fe_8fbd_4471_9acb_87493a348895
initial concentration: NaN
is: SBO:0000252
type: Species
is encoded by: hsa:622
has only substance units: false
boundary condition: true
name: BDH1
constant: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#e0950d4f_5d70_44e6_ac16_a1dfb57f2965
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bc4e629d_b385_481a_81a2_e3ea1863bf6b
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f3773ef5_531d_4bee_b927_f78e5916ef60
value: 0.0
type: LocalParameter

metaM tdechola e
notes: FORMULA: C26H44NO6S CHARGE: -1 INCHI: InChI=1S/C26H45NO6S/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-/m1/s1
initial concentration: 1.0
is: HMDB00896
has only substance units: false
is: CHEBI:9410
is: SBO:0000247
name: Taurodeoxycholic acid
type: Species
is: C05463
boundary condition: false
initial amount: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_3866adcd_0071_427f_a51e_518cf3e5dc96
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f9fdc27a_750d_4bb4_b6cf_d4fd1629f903
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e18af408_5ac1_4587_85ad_3a410fd0b709
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_77f6838d_c334_4a8d_9d7b_ee5a045ac284
constant: false
is encoded by: hsa:2954
name: GSTZ1
initial amount: NaN
has only substance units: false
is: SBO:0000252
type: Species
initial concentration: NaN
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1109130000#_26bee089_5040_4da2_8c61_6b2af84fad38
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b48bacc5_3fc0_4c41_9a48_201d46906f3b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d7d4df81_83a7_400b_b26f_eb98222f5062
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_100ba3fe_4a81_476f_ada9_9ae7126384eb
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9db18dbe_8796_4eb4_b73a_54d36d1f6919
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_63dc3c68_f8ac_4c3f_a17e_3cbb37783969
initial concentration: NaN
initial amount: NaN
name: GMPS
is: P49915
has only substance units: false
boundary condition: true
is: SBO:0000252
notes: DRUGBANK_SUBSTRATE: DB00130 DRUGBANK_UNKNOWN: DB00142
constant: false
is encoded by: hsa:8833
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#fc18d7be_f1ed_4a91_9025_b92d47fed2a0
value: 1000.0
type: LocalParameter

metaM ksii core2 pre10 g
initial amount: NaN
initial concentration: 1.0
notes: FORMULA: C81H130N6O64S2X CHARGE: -3 INCHI:
type: Species
boundary condition: false
constant: false
is: SBO:0000247
has only substance units: false
name: keratan sulfate II biosynthesis, precursor 10

http://identifiers.org/biomodels.db/MODEL1109130000#ff23a987_98af_4856_8afa_114d041d0847
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5cd20510_e823_4e2d_94de_b44dcebcf01b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_4634c1ed_aa3d_410b_a3c8_44be2d971cf9
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d8f94a1b_852c_406e_96cc_583d15568bf7
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6cf621b5_c51b_41a2_bd37_5c7301415844
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c98cbda1_8fda_4bd1_9702_790c66e70d67
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e0ae68da_0424_48ac_8375_e9cdabdbf5c9
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_378bed6c_0299_4212_873b_16cf36b4c56c
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f705a9e1_a8fe_4b74_9e5d_391d2251e381
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_323b8450_c09b_4e5a_8ea4_9d949c9d0968
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7756618b_9d9c_4ebb_90ce_6d897dc86b88
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9c329ec6_0e64_4cb3_a189_e35ccb286be0
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0e20911c_304d_40e0_9cc3_a6f6ee03096e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#fecfd906_0920_43f6_8e7e_60201d8dcbfe
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2e79301d_07eb_4ca5_883e_64e0dc00692a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_80186959_44bc_49ed_ab6d_9b41e5c54d30
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#bcca951d_7ba7_428f_85b9_a56a37566f07
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_977667a3_5e27_48f0_8c64_955b94d7f3a5
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_7b88feb5_bab4_4d7e_b3e8_1f6ee43c4472
boundary condition: true
initial concentration: NaN
is: P57103
initial amount: NaN
is encoded by: hsa:6547
constant: true
type: Species
has only substance units: false
is: SBO:0000252
name: SLC8A3

http://identifiers.org/biomodels.db/MODEL1109130000#_9f3dd29d_101e_49c6_a37f_d45f19ef92c2
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c41f616d_3264_4456_8d18_2979255d6c29
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_968321a1_6c28_43e0_ade6_7175a6c2c8c1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_31063b13_f4ee_48d4_bd11_61875ac30f18
units: dimensionless
value: 0.0
type: LocalParameter

metaM CE4830 c
name: 2-trans-9,12,15,18-all-cis-tetracosapentaenoyl-CoA
has only substance units: false
constant: false
is: SBO:0000247
initial concentration: 1.0
notes: FORMULA: C45H68N7O17P3S CHARGE: -4 INCHI: InChI=1/C45H72N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-36(54)73-29-28-47-35(53)26-27-48-43(57)40(56)45(2,3)31-66-72(63,64)69-71(61,62)65-30-34-39(68-70(58,59)60)38(55)44(67-34)52-33-51-37-41(46)49-32-50-42(37)52/h8-9,11-12,14-15,17-18,24-25,32-34,38-40,44,55-56H,4-7,10,13,16,19-23,26-31H2,1-3H3,(H,47,53)(H,48,57)(H,61,62)(H,63,64)(H2,46,49,50)(H2,58,59,60)/p-4/b9-8-,12-11-,15-14-,18-17-,25-24+/t34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4830
boundary condition: false
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#b1ada23c_ca5d_48ac_aeb2_5dd9374f300d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8305d81b_eaf3_4abf_b5fe_d4e786ba8e11
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#db3732e5_6c84_495f_9101_3cacbc414345
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8234b3de_bfbd_4d14_96ba_ec04c92e890e
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_64f8f7c7_3f9b_41b0_bed3_d2676f624021
is: O60476
has only substance units: false
initial concentration: NaN
boundary condition: true
is encoded by: hsa:10905
type: Species
name: MAN1A2
constant: true
is: SBO:0000252
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_5f5ec6c0_2b94_49fc_a61e_706869b82f99
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d7a1d258_30dd_4794_a988_d94da0dac3ac
is: SBO:0000297
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
name: ATP5H:ATP5L:NSF:ATP5F1:ATP5G3:ATP5I:ATP5J:ATP5J2
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_1b3b6560_f1ed_48af_8149_1a09358a8dc9
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#d2222ec0_f724_4da0_9575_ae242f304208
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f82fe3e5_d98b_4b09_b08b_968cae2f5ea3
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0c249f54_5c1e_437e_a0a7_838ea26eb323
value: 0.0
type: LocalParameter

metaR RE2117M
fast: false
product: MODEL1109130000#
is: SBO:0000176
modifier: MODEL1109130000#
notes: GENE_ASSOCIATION: 10249.1 SUBSYSTEM: Glycine, serine, alanine and threonine metabolism EC Number: 2.3.1.13 Confidence Level: 0 AUTHORS: PMID:10079066,PMID:10903396 NOTES:
is described by: http://identifiers.org/pubmed/10079066
reversible: true
is described by: http://identifiers.org/pubmed/10903396
type: Reaction
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/2.3.1.13
name: RE2117

http://identifiers.org/biomodels.db/MODEL1109130000#fa2dcedb_df92_436f_a71a_46b4534e739c
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_285012cd_136b_45d7_b7b3_98ee0d0585df
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5afa3205_56c8_40a1_9a36_6d389c9a48ba
is: SBO:0000252
boundary condition: true
type: Species
is: O95045
has only substance units: false
name: UPP2
initial amount: NaN
is encoded by: hsa:151531
initial concentration: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6e253934_3416_49d2_864e_8160ce1a1463
value: -1000.0
type: LocalParameter

metaM cs d deg4 l
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4
is: SBO:0000247
initial concentration: 1.0
boundary condition: false
notes: FORMULA: C31H47NO35S3 CHARGE: -4 INCHI:
type: Species
has only substance units: false
initial amount: NaN
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_6d603b14_410f_40b2_b108_1e6dae60e177
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a29d85ff_f879_4de6_88dd_0255879e765a
value: -1000.0
type: LocalParameter

metaM CE4830 r
boundary condition: false
initial concentration: 1.0
constant: false
has only substance units: false
notes: FORMULA: C45H68N7O17P3S CHARGE: -4 INCHI: InChI=1/C45H72N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-36(54)73-29-28-47-35(53)26-27-48-43(57)40(56)45(2,3)31-66-72(63,64)69-71(61,62)65-30-34-39(68-70(58,59)60)38(55)44(67-34)52-33-51-37-41(46)49-32-50-42(37)52/h8-9,11-12,14-15,17-18,24-25,32-34,38-40,44,55-56H,4-7,10,13,16,19-23,26-31H2,1-3H3,(H,47,53)(H,48,57)(H,61,62)(H,63,64)(H2,46,49,50)(H2,58,59,60)/p-4/b9-8-,12-11-,15-14-,18-17-,25-24+/t34-,38+,39+,40u,44-/m0/s1 EHMN_ABBREVIATION: CE4830
type: Species
name: 2-trans-9,12,15,18-all-cis-tetracosapentaenoyl-CoA
is: SBO:0000247
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_9cdc4e1c_92e9_40bf_83a0_7edcaa0c0d57
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_78ff211f_1e45_4208_9682_2bfb7a231899
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a50f8c3f_386b_4d80_a31f_b9f55c5a60c7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b677e7c5_d5a3_4fa1_a681_a587889541e5
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#eb29b79b_288f_4ebc_a5b0_f3681a25aba2
units: dimensionless
value: 0.0
type: LocalParameter

metaM HC00617 c
boundary condition: false
name: Ferricytochrome b5
has only substance units: false
constant: false
is: SBO:0000247
is: CHEBI:18097
initial amount: NaN
type: Species
initial concentration: 1.0
notes: FORMULA: CHARGE: 0 EHMN_ABBREVIATION: C00996

metaR RE3226C
reactant: MODEL1109130000#
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Fatty acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:10970790 NOTES:
is: SBO:0000176
product: MODEL1109130000#
reversible: false
name: RE3226
is described by: http://identifiers.org/pubmed/10970790
fast: false

metaM pail35p hs c
name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-)
initial amount: NaN
is: SBO:0000247
is: CHEBI:57923
boundary condition: false
initial concentration: 1.0
constant: false
has only substance units: false
notes: FORMULA: C9H14O15P3FULLRCO2FULLR2CO2 CHARGE: -5 INCHI:
type: Species

metaM CE7090 c
notes: FORMULA: C20H29O3 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE7090
is: SBO:0000247
has only substance units: false
name: 18R-HEPE
type: Species
boundary condition: false
constant: false
initial amount: NaN
initial concentration: 1.0

http://identifiers.org/biomodels.db/MODEL1109130000#_16e382c8_e5e0_414c_8b08_b758f4b5174b
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e5d2c4a6_84cc_4f07_8705_4f78a898c083
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_91789130_ebee_46d8_8d3d_008c42ffc17a
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_9fafdd18_5a23_4984_a832_57e63629b231
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_35c1a1b9_3fdc_4088_a8ff_36a8e2e1ec17
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dff3840d_5233_473e_94e8_d2e757e72d73
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_297d3715_e068_4092_b5e5_a897709fd469
units: dimensionless
value: 0.0
type: LocalParameter

metaR RE2705C
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin E metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11890747,PMID:9789014 NOTES:
name: RE2705
reversible: true
is described by: http://identifiers.org/pubmed/11890747
product: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/9789014
type: Reaction
fast: false

http://identifiers.org/biomodels.db/MODEL1109130000#_80fd9e0a_d6ba_4fb0_a12a_6e1a32c6f167
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3a81e2c1_411d_41aa_a0a5_28a0a0213b30
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2f7e9d4d_4f59_4015_bf8a_db968e5081dc
constant: false
is encoded by: hsa:64080
type: Species
initial amount: NaN
initial concentration: NaN
boundary condition: true
is: Q9H477
is: SBO:0000252
name: RBKS
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_080d26d7_f43d_426d_8a92_13a24c5ed969
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_72662766_7ad8_4e7a_bb20_54aa52d4530d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c3db9f44_132d_4167_8ddd_03f1ca13d811
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_17c46d1c_17ab_42d0_bf5b_df38f69f31a7
value: 1000.0
type: LocalParameter

metaR r1871
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
name: Y+LAT2 Utilized transport
fast: false
reversible: false
modifier: MODEL1109130000#
is: SBO:0000185
reactant: MODEL1109130000#
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_959ef42e_e9da_49d2_be4f_35ade165ef63
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_8164dc9b_9428_4155_9fc1_a44e972a9946
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#dd2325f6_59f0_4444_b5a0_dd37724bb094
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_91f1bc9f_1673_4bc0_b08a_61c0b0d39c49
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3c511836_ccd4_4ead_83ce_1fc10856b624
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_875f275a_6ae5_49e7_9b98_a0000a80e2c9
value: 1000.0
type: LocalParameter

metaR RE2636R
modifier: MODEL1109130000#
product: MODEL1109130000#
reactant: MODEL1109130000#
fast: false
is: SBO:0000176
name: RE2636
reversible: false
is described by: http://identifiers.org/pubmed/11980911
notes: GENE_ASSOCIATION: 1582.1 SUBSYSTEM: Bile acid synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:11980911 NOTES:
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_62c2a242_0225_4b19_b8bb_d606f57a6649
value: 0.0
type: LocalParameter

metaR ENMAN2g
fast: false
is version of: ECO:0000000
reversible: false
name: Endomannosidase (glc2man-producing), Golgi apparatus
product: MODEL1109130000#
type: Reaction
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11007802
is: SBO:0000176
is described by: http://identifiers.org/pubmed/12770767
notes: GENE_ASSOCIATION: SUBSYSTEM: N-glycan synthesis EC Number: Confidence Level: 0 AUTHORS: PMID:11007802,PMID:12770767 NOTES: NCD

http://identifiers.org/biomodels.db/MODEL1109130000#_2e26214d_4e53_4efa_9a5a_bfde9c33d371
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_5d9dcd66_8b6f_4269_8839_8973e9bd7aa7
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f2c78a50_c966_448b_9cba_023f6c60b055
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_021b8106_79be_4a82_bbcc_8f50424e020c
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b0c40714_ecc9_49b2_b24b_8441cf9f8a93
value: 1000.0
type: LocalParameter

metaR r1872
name: Y+LAT2 Utilized transport
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770310
reactant: MODEL1109130000#
reversible: false
fast: false
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
type: Reaction
modifier: MODEL1109130000#
is: SBO:0000185

metaR RE3022C
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/9862787
is: SBO:0000176
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/11368003
type: Reaction
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid metabolism EC Number: Confidence Level: 0 AUTHORS: PMID:11368003,PMID:9799565,PMID:9862787 NOTES:
reversible: true
is described by: http://identifiers.org/pubmed/9799565
name: RE3022

http://identifiers.org/biomodels.db/MODEL1109130000#_05f6d1be_d6d9_4852_b16a_5b62d63c22db
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3736e211_c5ed_453c_9398_c19be2412014
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6dc7edb3_6c75_470f_a8a0_600165b6da87
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#cb064a52_04c8_463c_92b8_03b74c589807
units: dimensionless
value: 0.0
type: LocalParameter

metaM mercplac c
notes: FORMULA: C3H5O3S CHARGE: -1 INCHI: InChI=1/C3H6O3S/c4-2(1-7)3(5)6/h2,4,7H,1H2,(H,5,6) EHMN_ABBREVIATION: C05823
has only substance units: false
is: HMDB02127
boundary condition: false
initial amount: NaN
is: http://identifiers.org/pubchem.substance/8118
is: C05823
is: SBO:0000247
type: Species
initial concentration: 1.0
constant: false
name: 3-Mercaptolactate

http://identifiers.org/biomodels.db/MODEL1109130000#_7c531d35_5902_4263_8c54_6d06ae9d441e
value: 0.0
type: LocalParameter

metaM C02470 c
is: C02470
constant: false
is: SBO:0000247
initial amount: NaN
has only substance units: false
is: HMDB00881
type: Species
notes: FORMULA: C10H6NO4 CHARGE: -1 INCHI: InChI=1/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15) HEPATONET_1.0_ABBREVIATION: HC00945 EHMN_ABBREVIATION: C02470
initial concentration: 1.0
is: http://identifiers.org/pubchem.substance/5485
name: Xanthurenic acid
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1109130000#_0dbe8e1f_b780_4a3e_9065_8cfbdd545e44
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_313d6ec4_aae8_460e_9a78_b445d2667a4f
units: dimensionless
value: 0.0
type: LocalParameter

metaM pail35p hs g
type: Species
is: CHEBI:57923
name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-)
boundary condition: false
has only substance units: false
is: SBO:0000247
initial amount: NaN
constant: false
initial concentration: 1.0
notes: FORMULA: C9H14O15P3FULLRCO2FULLR2CO2 CHARGE: -5 INCHI:

http://identifiers.org/biomodels.db/MODEL1109130000#a545ca78_7dd1_46cb_882b_3121c9104bbf
value: 0.0
type: LocalParameter

metaR r1873
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
fast: false
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
name: Y+LAT2 Utilized transport
reversible: false
reactant: MODEL1109130000#
is: SBO:0000185
modifier: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770309
type: Reaction

http://identifiers.org/biomodels.db/MODEL1109130000#_8a6c4a02_914a_4793_8503_1d04bfa9e7fe
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#caf18e1d_11d5_469d_ac8e_18086dadf83a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_45dba9da_cf92_4bb8_987f_8c7b0913a97b
value: 1000.0
type: LocalParameter

metaR TRPHYDRO2
notes: GENE_ASSOCIATION: (7166.1) or (121278.1) SUBSYSTEM: Tryptophan metabolism EC Number: 1.14.16.4 Confidence Level: 4 AUTHORS: PMID:10727395,PMID:12379098 NOTES: SAB unlumped version of TRPHYDRO1
is described by: http://identifiers.org/pubmed/10727395
reactant: MODEL1109130000#
is version of: http://identifiers.org/ec-code/1.14.16.4
is version of: ECO:0000269
fast: false
is: SBO:0000176
product: MODEL1109130000#
reversible: false
name: L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
is described by: http://identifiers.org/pubmed/12379098
type: Reaction
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_266e5226_8262_4d50_83b9_99eeab2e12ca
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#f04048ca_264b_44b6_a58c_d4b213fcbe36
value: -1000.0
type: LocalParameter

metaR RE0925R
reversible: false
reactant: MODEL1109130000#
product: MODEL1109130000#
is described by: http://identifiers.org/pubmed/8070342
is version of: http://identifiers.org/ec-code/2.4.1.17
notes: GENE_ASSOCIATION: (54600.1) or (10720.1) or (7367.1) or (7363.1) or (7364.1) or (54578.1) or (54657.1) or (54659.1) or (54579.1) or (7365.1) or (7366.1) or (54490.1) or (54577.1) or (54575.1) or (54658.1) SUBSYSTEM: Tyrosine metabolism EC Number: 2.4.1.17 Confidence Level: 0 AUTHORS: PMID:2229315,PMID:8070342,PMID:9633995 NOTES:
fast: false
is described by: http://identifiers.org/pubmed/9633995
type: Reaction
modifier: MODEL1109130000#
is: SBO:0000176
is described by: http://identifiers.org/pubmed/2229315
name: RE0925

http://identifiers.org/biomodels.db/MODEL1109130000#_cbfda672_83ed_4587_88a4_49c67b29856c
name: SLC35A3
is: Q9Y2D2
initial concentration: NaN
boundary condition: true
type: Species
is encoded by: hsa:23443
constant: false
has only substance units: false
is: SBO:0000252
initial amount: NaN

metaM CE5236 n
initial amount: NaN
has only substance units: false
boundary condition: false
initial concentration: 1.0
constant: false
type: Species
name: O2-4a-cyclic-tetrahydrobiopterin
is: SBO:0000247
notes: FORMULA: C9H13N5O3 CHARGE: 0 INCHI: InChI=1/C9H13N5O3/c1-3-5(15)4-2-11-6-9(14-4,17-3)7(16)13-8(10)12-6/h3-5,14-15H,2H2,1H3,(H3,10,11,12,13,16)/p+1/t3-,4u,5+,9u/m0/s1 EHMN_ABBREVIATION: CE5236

metaR r1874
modifier: MODEL1109130000#
name: Y+LAT2 Utilized transport
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770310
fast: false
type: Reaction
reversible: false
is described by: http://identifiers.org/pubmed/14770309
is: SBO:0000185
product: MODEL1109130000#

metaR RE2031M
is version of: http://identifiers.org/ec-code/2.3.1.1
modifier: MODEL1109130000#
reversible: true
is described by: http://identifiers.org/pubmed/12594532
type: Reaction
product: MODEL1109130000#
reactant: MODEL1109130000#
notes: GENE_ASSOCIATION: 162417.1 SUBSYSTEM: Alanine and aspartate metabolism EC Number: 2.3.1.1 Confidence Level: 0 AUTHORS: PMID:12459178,PMID:12594532 NOTES:
is: SBO:0000176
fast: false
is described by: http://identifiers.org/pubmed/12459178
name: RE2031

http://identifiers.org/biomodels.db/MODEL1109130000#_44ab011f_704d_4953_80a4_6e08bf2083b3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_78e0e6ed_fc82_4ad6_9cdb_fec3da5af4a7
is: SBO:0000252
boundary condition: true
type: Species
initial concentration: NaN
name: ENTPD3
is encoded by: hsa:956
has only substance units: false
constant: false
initial amount: NaN
is: O75355

http://identifiers.org/biomodels.db/MODEL1109130000#_91673ccc_397b_400e_8b33_257075f36ae1
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_3e6dc917_f484_4d74_8f38_a9e6eca002e2
units: dimensionless
value: 0.0
type: LocalParameter

metaR PPCDC
is version of: ECO:0000269
modifier: MODEL1109130000#
is version of: http://identifiers.org/ec-code/4.1.1.36
reactant: MODEL1109130000#
reversible: false
is described by: http://identifiers.org/pubmed/11923312
is: SBO:0000176
fast: false
name: phosphopantothenoylcysteine decarboxylase
notes: GENE_ASSOCIATION: 60490.1 SUBSYSTEM: CoA synthesis EC Number: 4.1.1.36 Confidence Level: 4 AUTHORS: PMID:11923312 NOTES:
type: Reaction
product: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_96e478e2_4275_4f78_b34d_79a03ecb88f1
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_27c6ae80_12fe_469e_9937_0bb90d1d5b0a
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_b1356c40_f0d8_4b34_97d9_c099410e8291
initial amount: NaN
boundary condition: true
is encoded by: hsa:10935
type: Species
is: E9PH29
initial concentration: NaN
is: SBO:0000252
constant: true
has only substance units: false
name: PRDX3

metaR ORETNF2
is: SBO:0000176
is version of: ECO:0000000
reversible: false
product: MODEL1109130000#
name: 13-cis-4-oxo-retinoic acid formation (oxidation)
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A metabolism EC Number: Confidence Level: 2 AUTHORS: PMID:1503811 NOTES: IT
reactant: MODEL1109130000#
fast: false
type: Reaction
is described by: http://identifiers.org/pubmed/1503811

http://identifiers.org/biomodels.db/MODEL1109130000#_288ac852_707d_48d9_adee_9d3b58b05ef8
value: 0.0
type: LocalParameter

metaM g1m7masnC r
has only substance units: false
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)
initial concentration: 1.0
is: SBO:0000247
constant: false
initial amount: NaN
boundary condition: false
type: Species
notes: FORMULA: C70H117N2O55X CHARGE: 0 INCHI:

metaR RE3189M
fast: false
reversible: true
is: SBO:0000176
is described by: http://identifiers.org/pubmed/9469587
type: Reaction
is described by: http://identifiers.org/pubmed/10407780
product: MODEL1109130000#
modifier: MODEL1109130000#
name: RE3189
is described by: http://identifiers.org/pubmed/9819701
is version of: http://identifiers.org/ec-code/2.3.1.16
notes: GENE_ASSOCIATION: (10449.1) or (3032.1) or (3030.1) SUBSYSTEM: Fatty acid oxidation EC Number: 2.3.1.16 Confidence Level: 0 AUTHORS: PMID:10407780,PMID:9469587,PMID:9819701 NOTES:
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#f0cd837a_8b01_45a4_8c6f_e30aea203b76
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#b466fc7c_b83b_455e_8b50_fee955af01b8
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_0f64bbfb_49be_4ffd_8e8f_5e7b1b1c3861
is: Q8NBZ7
initial amount: NaN
boundary condition: true
has only substance units: false
is: SBO:0000252
constant: true
name: UXS1
initial concentration: NaN
type: Species
is encoded by: hsa:80146

http://identifiers.org/biomodels.db/MODEL1109130000#_bb074501_af32_4d5b_875d_4e2ca5311d0c
is: P49189
notes: DRUGBANK_UNKNOWN: DB00157, DB01907
name: ALDH9A1
type: Species
has only substance units: false
initial amount: NaN
constant: false
initial concentration: NaN
boundary condition: true
is encoded by: hsa:223
is: SBO:0000252

metaM c12dc e
type: Species
has only substance units: false
constant: false
initial amount: NaN
name: dodecanedioyl carnitine
is: SBO:0000247
initial concentration: 1.0
notes: FORMULA: C19H34NO6 CHARGE: -1
boundary condition: false

metaR r1865
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is: SBO:0000185
fast: false
type: Reaction
name: Y+LAT2 Utilized transport
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
product: MODEL1109130000#
modifier: MODEL1109130000#
reversible: false
reactant: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#_4e3d1b66_a319_4360_bc47_b93a4ddf1908
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_99f2c9f9_2bf7_472b_8988_26e255c209f2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c3d37242_6536_4a1e_b753_7bcba5e64c97
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_6119385b_b488_4ae3_bda1_d28482667b05
boundary condition: true
initial amount: NaN
is: P31327
has only substance units: false
type: Species
is encoded by: hsa:1373
constant: true
name: CPS1
is: SBO:0000252
initial concentration: NaN

http://identifiers.org/biomodels.db/MODEL1109130000#_78891ccc_cc5e_4920_8aa0_2691fed49a9f
value: 0.0
type: LocalParameter

metaM lgnccrn m
initial amount: NaN
initial concentration: 1.0
type: Species
name: lignoceryl carnitine
is: SBO:0000247
boundary condition: false
notes: FORMULA: C31H61NO4 CHARGE: 0 INCHI:
has only substance units: false
constant: false

http://identifiers.org/biomodels.db/MODEL1109130000#_2e29ba09_80b1_4966_9589_db6f21f982cb
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_92e5a514_b1c4_45c1_bb59_b60627a2b8b9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_925d9c31_914e_4e32_91bc_b461f66194fe
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#e4e99919_d3da_4725_a819_34aeaa4cd4f2
units: dimensionless
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a42da488_63dc_43af_bb8a_1ff6b084f3c3
value: 0.0
type: LocalParameter

metaM CE5316 m
name: 8(R)-hydroxy-hexadeca-4E,6E,10Z-trienoate
boundary condition: false
initial amount: NaN
notes: FORMULA: C16H25O3 CHARGE: -1 INCHI: EHMN_ABBREVIATION: CE5316
initial concentration: 1.0
constant: false
has only substance units: false
is: SBO:0000247
type: Species

http://identifiers.org/biomodels.db/MODEL1109130000#_aafdf0d2_8f28_4ab9_b497_7df69cda3866
name: NAGLU
is: SBO:0000252
initial concentration: NaN
boundary condition: true
type: Species
is encoded by: hsa:4669
is: P54802
constant: true
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1109130000#_4d482a08_7144_4d88_a4f2_a75157c21fe5
boundary condition: true
has only substance units: false
constant: true
is encoded by: hsa:8527
initial concentration: NaN
type: Species
is: SBO:0000252
initial amount: NaN
name: DGKD

metaR r1864
product: MODEL1109130000#
is: SBO:0000185
fast: false
reactant: MODEL1109130000#
is described by: http://identifiers.org/pubmed/14770310
modifier: MODEL1109130000#
reversible: false
type: Reaction
name: Y+LAT2 Utilized transport
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
is described by: http://identifiers.org/pubmed/14770309

http://identifiers.org/biomodels.db/MODEL1109130000#_66584f8c_167a_4142_aa9e_bd1564ce0b71
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#a8a6cbff_ccdd_4a8a_b387_91f9f97e1fde
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_2928030f_2c17_4a9b_bb60_06d857cb1b2b
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#_926c5a5d_04ea_45ce_95f6_3a08dcf9e9a5
value: 1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#ecd2013d_b37a_4467_9215_309eeb418531
value: -1000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1109130000#c8d53559_ec9f_43ec_b7e2_804693a0fb19
units: dimensionless
value: 0.0
type: LocalParameter

metaM c12dc c
notes: FORMULA: C19H34NO6 CHARGE: -1
boundary condition: false
name: dodecanedioyl carnitine
is: SBO:0000247
has only substance units: false
initial amount: NaN
initial concentration: 1.0
type: Species
constant: false

metaR r1867
reversible: false
is: SBO:0000185
notes: GENE_ASSOCIATION: 9057.1 SUBSYSTEM: Transport, extracellular EC Number: Confidence Level: 0 AUTHORS: PMID:14770309,PMID:14770310 NOTES:
type: Reaction
fast: false
name: Y+LAT2 Utilized transport
is described by: http://identifiers.org/pubmed/14770309
is described by: http://identifiers.org/pubmed/14770310
reactant: MODEL1109130000#
product: MODEL1109130000#
modifier: MODEL1109130000#

http://identifiers.org/biomodels.db/MODEL1109130000#b37dd268_06da_4e2b_83ae_e35e9a6d7bb5
units: dimensionless
value: 0.0
type: LocalParameter