monoacylglycerol 2 (homo sapiens) exchange
GENE_ASSOCIATION: (35.1) or (34.1) SUBSYSTEM: Fatty acid oxidation
phosphatidylinositol 4,5-bisphosphate 3-kinase, nuclear
GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (669.1) or (5223.1) or (5224.2) or (5224.1) or (669.2) SUBSYSTEM: Glycolysis/Gluconeogenesis
L-leucine transport in via sodium symport
GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
GENE_ASSOCIATION: (7306.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
inositol 1,3,4,5,6-pentakisphosphate nuclear transport (diffusion)_fwd
GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (1376.1) SUBSYSTEM: Carnitine shuttle
Dolichol phosphate, human uterine homolog
GENE_ASSOCIATION: (6570.1) or (6571.1) SUBSYSTEM: Transport, Extracellular
Dopamine secretion via secretory vesicle (ATP driven)
nucleoside-diphosphate kinase (ATP:dIDP), mitochondrial_fwd
GENE_ASSOCIATION: (4833.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (3074.1) or (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Keratan sulfate degradation
blood group intracellular transport_bkwd
GENE_ASSOCIATION: (10690.1) SUBSYSTEM: Blood Group Biosynthesis
transport into the mitochondria (carnitine)
GENE_ASSOCIATION: (788.1) SUBSYSTEM: Carnitine shuttle
GENE_ASSOCIATION: (8639.1) or (26.1) or (314.2) or (314.1) SUBSYSTEM: beta-Alanine metabolism
1,3-Diaminopropane:oxygen oxidoreductase (deaminating)
4-hydroxyretinoic acid transport, Nuclear_bkwd
GENE_ASSOCIATION: (51727.1) SUBSYSTEM: Nucleotides
chondroitin sulfate A (GalNAc4S-GlcA) proteoglycan
GENE_ASSOCIATION: (83884.1) or (10166.1) SUBSYSTEM: Transport, Mitochondrial
ornithine mitochondrial transport via proton antiport_bkwd
GENE_ASSOCIATION: (50808.1) SUBSYSTEM: Nucleotides
Gal-GlcNAc-Gal globoside (homo sapiens) exchange
L-sulfolactate dehydrogenase (NAD+), mitochondrial_fwd
GENE_ASSOCIATION: (4191.1) SUBSYSTEM: Cysteine Metabolism
beta-N-acetylhexosaminidase A, lysosomal
GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Chondroitin sulfate degradation
GENE_ASSOCIATION: (6536.1) or (6536.2) SUBSYSTEM: Transport, Extracellular
glycine reversible transport via sodium and chloride symport (2:1:1)_fwd
GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (8704.1) or (8703.1) or (2683.1) or (9334.1) or (8704.2) SUBSYSTEM: Keratan sulfate biosynthesis
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Golgi
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 2
AMP/ATP transporter, endoplasmic reticulum_bkwd
ornithine mitochondrial transport exchange with citruline_bkwd
GENE_ASSOCIATION: (10166.1) or (83884.1) SUBSYSTEM: Transport, Mitochondrial
Asparagine transport (Na, H coupled)_bkwd
GENE_ASSOCIATION: (92745.1) or (10991.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
GENE_ASSOCIATION: (2098.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (5831.1) or (5831.2) SUBSYSTEM: Arginine and Proline Metabolism
keratan sulfate I, degradation product 11
GENE_ASSOCIATION: (3423.2) or (3423.1) SUBSYSTEM: Chondroitin sulfate degradation
GENE_ASSOCIATION: (2679.1) or (2678.1) or (2678.3) or (2678.2) SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (6566.1) SUBSYSTEM: Transport, Mitochondrial
nucleoside-diphosphate kinase (ATP:dUDP)_fwd
GENE_ASSOCIATION: (80235.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
H6 mannosyltransferase, endoplasmic reticulum
GENE_ASSOCIATION: SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
malonate-semialdehyde dehydrogenase (acetylating), mitochondrial
keratan sulfate I, degradation product 27
GENE_ASSOCIATION: (60386.1) SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: (79717.1) SUBSYSTEM: CoA Biosynthesis
GENE_ASSOCIATION: (3073.1 and 3074.1) or (3074.1) or (3073.1) SUBSYSTEM: Keratan sulfate degradation
GENE_ASSOCIATION: (2356.1) SUBSYSTEM: Folate Metabolism
folylpolyglutamate synthetase, mitochondrial
GENE_ASSOCIATION: (18.1) or (18.2) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
L-3-aminoisobutyrate transaminase, mitochondrial_fwd
chondroitin sulfate D (GlcNAc6S-GlcA2S), free chain
GENE_ASSOCIATION: (412.1) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (55217.1) SUBSYSTEM: Lysine Metabolism
GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) or (3074.1) SUBSYSTEM: Keratan sulfate degradation
keratan sulfate I biosynthesis, precursor 20
GENE_ASSOCIATION: (10087.1) SUBSYSTEM: Transport, Endoplasmic Reticular
GENE_ASSOCIATION: (8659.2) or (219.1) or (8659.1) or (217.1) SUBSYSTEM: Tryptophan metabolism
5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase (mito)
GENE_ASSOCIATION: SUBSYSTEM: Phenylalanine metabolism
GENE_ASSOCIATION: (89874.1) SUBSYSTEM: Tryptophan metabolism
2-oxoadipate shuttle (cytosol/mitochondria)_bkwd
GENE_ASSOCIATION: (55301.1) SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (3177.1) SUBSYSTEM: Transport, Extracellular
thymine reversible transport via facilated diffusion_fwd
GENE_ASSOCIATION: SUBSYSTEM: Heparan sulfate degradation
N-acetylglucosamine-3-sulfatase, lysosomal_fwd
GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: Keratan sulfate degradation
GENE_ASSOCIATION: (54575.1) or (54576.1) SUBSYSTEM: Steroid Metabolism
UDP-glucuronosyltransferase 1-10 precursor, microsomal
GENE_ASSOCIATION: (2987.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (6523.1) SUBSYSTEM: Transport, Extracellular
lipid, flip-flop intracellular transport_fwd
GENE_ASSOCIATION: (366.1) SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
acetaldehyde mitochondrial diffusion_fwd
GENE_ASSOCIATION: (2180.1) SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (6448.1) SUBSYSTEM: Heparan sulfate degradation
25 trihydroxy cholesterol transport_bkwd
GENE_ASSOCIATION: (130752.1) or (4190.1) SUBSYSTEM: Citric Acid Cycle
5-formyltetrahydrofolate transport via anion exchange_fwd
GENE_ASSOCIATION: (6573.1) or (6573.2) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (10998.1) or (11001.1) SUBSYSTEM: Transport, Extracellular
fatty acid electroneutral transport_bkwd
5-Methyltetrahydrofolate transport via receptor binding and protolysis_bkwd
GENE_ASSOCIATION: (84002.1) SUBSYSTEM: Blood Group Biosynthesis
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
GENE_ASSOCIATION: (2030.1) SUBSYSTEM: Transport, Mitochondrial
protein trimethyl lysine transport (nucleus to ER)
GENE_ASSOCIATION: (8288.1) SUBSYSTEM: Miscellaneous
dodecenoyl-Coenzyme A delta isomerase_fwd
GENE_ASSOCIATION: (1632.1) SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
GENE_ASSOCIATION: (1807.1) or (1809.1) or (1808.1) SUBSYSTEM: Pyrimidine Catabolism
phosphatidylinositol-3,5-bisphosphate (Homo sapiens)
Endomannosidase (glc1man-producing), Golgi apparatus
GENE_ASSOCIATION: SUBSYSTEM: N-Glycan Biosynthesis
GENE_ASSOCIATION: (34.1) or (35.1) SUBSYSTEM: Fatty acid oxidation
4-aminobutyrate transaminase, reversible (mitochondrial)_bkwd
GENE_ASSOCIATION: (18.1) or (18.2) SUBSYSTEM: Glutamate metabolism
disialyl galactosylgloboside (homo sapiens)
keratan sulfate I, degradation product 24
GENE_ASSOCIATION: (8703.1) or (2683.1) or (8704.2) or (8704.1) or (9334.1) SUBSYSTEM: Keratan sulfate biosynthesis
GENE_ASSOCIATION: (5337.1) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (7364.1) or (54575.1) or (54490.1) or (54576.1) or (7367.1) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (6120.1) or (6120.2) SUBSYSTEM: Pentose Phosphate Pathway
Beta-galactoside alpha-2,3-sialyltransferase
GENE_ASSOCIATION: (29906.1) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
glycine-cleavage complex (lipoylprotein), mitochondrial_fwd
2-methylcitrate transport via diffusion_bkwd
Cyanide transport via diffusion (extracellular to cytosol)_bkwd
GENE_ASSOCIATION: (10396.1) or (57194.1) SUBSYSTEM: Transport, Extracellular
3',5'-cyclic-nucleotide phosphodiesterase,Golgi
GENE_ASSOCIATION: (10846.1) SUBSYSTEM: Nucleotides
isoleucine transaminase, mitochondrial_bkwd
GENE_ASSOCIATION: (587.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
cytidine facilated transport in cytosol_bkwd
GENE_ASSOCIATION: (3177.1) or (2030.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (1571.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) or (3295.1 and 30.1 and 51.2) SUBSYSTEM: Fatty acid oxidation, peroxisome
GENE_ASSOCIATION: (206358.1) SUBSYSTEM: Transport, Lysosomal
4-aminobutyrate reversible transport in via proton symport (lysosome)_fwd
GENE_ASSOCIATION: SUBSYSTEM: Lysine Metabolism
delta1-piperideine-2-carboxylate reductase, perixosomal
GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
UDPglucuronate uridine-diphosphohydrolase
GENE_ASSOCIATION: (4860.1) or (151531.1) SUBSYSTEM: Nucleotides
Dolichyl phosphate D-mannose, human liver homolog
10-Formyltetrahydrofolate mitochondrial transport via diffusion_fwd
GENE_ASSOCIATION: (55312.1) SUBSYSTEM: Riboflavin Metabolism
GENE_ASSOCIATION: SUBSYSTEM: Transport, Golgi Apparatus
Thiamine triphosphate transport in via anion antiport
GENE_ASSOCIATION: SUBSYSTEM: Transport, Lysosomal
dihydrofolate reversible lysosomal transport_bkwd
dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase (liver)
GENE_ASSOCIATION: (79053.1) or (79053.3) or (79053.2) SUBSYSTEM: N-Glycan Biosynthesis
Dolichol-phosphate phosphohydrolase, human (liver)
deoxycytidine transport via diffusion_fwd
ADP/ATP transporter, endoplasmic reticulum_bkwd
N-acetylgalactosamine 3-alpha-galactosyltransferase, Golgi apparatus
GENE_ASSOCIATION: SUBSYSTEM: O-Glycan Biosynthesis
GENE_ASSOCIATION: (222.1) or (221.1) or (218.1) SUBSYSTEM: Tyrosine metabolism
3,4-Dihydroxyphenylacetaldehyde:NADP+ oxidoreductase_fwd
GENE_ASSOCIATION: (10090.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
methylglutaconyl-CoA hydratase (reversible), mitochondrial_fwd
GENE_ASSOCIATION: (549.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
L-cysteine/glycine reversible exchanger_bkwd
GENE_ASSOCIATION: (56301.1) and (6520.1) SUBSYSTEM: Transport, Extracellular
cholesterol intracellular transport_bkwd
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3
GENE_ASSOCIATION: (5805.1) SUBSYSTEM: Tetrahydrobiopterin
6-pyruvoyltetrahydropterin synthase, nuclear
GENE_ASSOCIATION: (10331.1) SUBSYSTEM: Sphingolipid Metabolism
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, Golgi apparatus
GENE_ASSOCIATION: SUBSYSTEM: Chondroitin sulfate degradation
degradation of proteoglycan linkage region, lysosomal
GENE_ASSOCIATION: (6560.1) or (10723.1) or (9990.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (80347.1) SUBSYSTEM: CoA Biosynthesis
GENE_ASSOCIATION: (8560.1) or (8560.2) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (2805.1) SUBSYSTEM: Alanine and Aspartate Metabolism
Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NADH)
GENE_ASSOCIATION: SUBSYSTEM: Ubiquinone Biosynthesis
3-Mercaptolactate:NAD+ oxidoreductase_bkwd
Gal-Gal-Gal-Gal-Gal-Glc-Cer (homo sapiens)
GENE_ASSOCIATION: (2523.1) SUBSYSTEM: Blood Group Biosynthesis
Galactoside 2-alpha-L-fucosyltransferase 1
L-cysteine/L-glutamine reversible exchanger_bkwd
GENE_ASSOCIATION: (6520.1) and (56301.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (9197.1) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (3283.1) SUBSYSTEM: Steroid Metabolism
3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I
GENE_ASSOCIATION: (4128.1) or (4129.1) SUBSYSTEM: Tryptophan metabolism
5-Hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)
hydrogen peroxide lysosomal transport via diffusion_bkwd
GENE_ASSOCIATION: (6513.1) SUBSYSTEM: Transport, Golgi Apparatus
GENE_ASSOCIATION: (231.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
D-mannose transport via sodium cotransport_bkwd
GENE_ASSOCIATION: (200010.1) SUBSYSTEM: Transport, Extracellular
phosphatidylinositol 4,5-bisphosphate 3-kinase
GENE_ASSOCIATION: (4363.1) SUBSYSTEM: Transport, Extracellular
aldehyde dehydrogenase (phenylacetaldehyde, NAD)
GENE_ASSOCIATION: (222.1) or (218.1) or (221.1) or (220.1) SUBSYSTEM: Phenylalanine metabolism
GENE_ASSOCIATION: (7378.2) or (151531.1) or (7378.1) SUBSYSTEM: Pyrimidine Catabolism
pyrimidine-nucleoside phosphorylase (uracil)_fwd
chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 4
inositol-1,4,5,6- tetrakisphosphate 3-kinase, nucleus
GENE_ASSOCIATION: (253430.1) SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (9415.1) SUBSYSTEM: Fatty acid elongation
fatty acyl-CoA desaturase (n-C18:2CoA -> n-C18:3CoA)
GENE_ASSOCIATION: (763.1) or (11238.1) SUBSYSTEM: Miscellaneous
4-oxo-retinoic acid formation (oxidation)
GENE_ASSOCIATION: (8705.1) SUBSYSTEM: Sphingolipid Metabolism
D-Serine/Glutamine reversible exchange_bkwd
alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human liver homolog
GENE_ASSOCIATION: (5625.1) SUBSYSTEM: Arginine and Proline Metabolism
Endomannosidase (m6masnB2-producing), Golgi apparatus
GENE_ASSOCIATION: (7173.4) or (7173.1) or (7173.3) or (7173.2) or (7173.5) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (1610.1) SUBSYSTEM: D-arg and D-orn metabolism
GENE_ASSOCIATION: (1040.1) SUBSYSTEM: Glycerophospholipid Metabolism
Thiamine transport in via proton antiport_bkwd
GENE_ASSOCIATION: (80704.1) or (10560.1) SUBSYSTEM: Transport, Extracellular
cytidylate kinase (dCMP,dGTP),nuclear_fwd
GENE_ASSOCIATION: (1468.1) SUBSYSTEM: Transport, Mitochondrial
Fumarate:thiosulfate antiport, mitochondrial_fwd
2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial
GENE_ASSOCIATION: (1629.1) and (594.1 and 593.1) and (1738.1) or (1629.1) and (1738.1) and (594.2 and 593.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (6583.1) SUBSYSTEM: Transport, Extracellular
L-carnitine outward transport (H+ antiport)
(alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
GENE_ASSOCIATION: SUBSYSTEM: Glycerophospholipid Metabolism
alkyl acylglycerol phosphocholine transferase
gulonolactone endoplasmic reticular transport
adenosine facilated transport from lysosome_fwd
GENE_ASSOCIATION: (55315.1) SUBSYSTEM: Transport, Lysosomal
GENE_ASSOCIATION: (10331.1) SUBSYSTEM: Blood Group Biosynthesis
alpha-N-acetylglucosaminyltransferase II
GENE_ASSOCIATION: (2131.1 and 2132.2) or (2137.1) or (2131.1 and 2132.1) or (2134.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
phosphoribosylpyrophosphate synthetase_fwd
GENE_ASSOCIATION: (221823.2) or (5631.1) or (221823.1) or (5634.1) SUBSYSTEM: Pentose Phosphate Pathway
3-Methyl-2-oxopentanoate mitochondrial transport via proton symport
sulfatide galactocerebroside (homo sapiens)
GENE_ASSOCIATION: (8394.1) or (23396.1) or (8395.1) SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol 3,4-bisphosphate 5-kinase
GENE_ASSOCIATION: (3155.1) or (54511.1) SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (51251.1) SUBSYSTEM: Pyrimidine Catabolism
L-Serine/Glutamine reversible exchange_fwd
Asparagine transport (Na, H coupled)_fwd
11-deoxycorticosterone intracellular transport_bkwd
GENE_ASSOCIATION: (6569.1) or (10568.1) SUBSYSTEM: Transport, Extracellular
phosphate transport in/out via three Na+ symporter_fwd
GENE_ASSOCIATION: (4190.1) or (130752.1) SUBSYSTEM: Cysteine Metabolism
1D-myo-Inositol 1,3,4,6-tetrakisphosphate nuclear transport (diffusion)_bkwd
fucgalgbside hs intracellular transport_fwd
GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) or (5476.1) and (2720.1) SUBSYSTEM: Keratan sulfate degradation
mesaconate--CoA ligase (GDP-forming)_fwd
GENE_ASSOCIATION: (8802.1 and 8801.1) SUBSYSTEM: C5-Branched dibasic acid metabolism
galactose-6-sulfate sulfatase, lysosomal_fwd
GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) SUBSYSTEM: Keratan sulfate degradation
GENE_ASSOCIATION: (66002.1) SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (65985.1) or (55902.2) or (55902.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
sphingosine intracellular transport_bkwd
GENE_ASSOCIATION: (1571.1) SUBSYSTEM: CYP Metabolism
1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)
GENE_ASSOCIATION: (1610.1) SUBSYSTEM: Arginine and Proline Metabolism
GENE_ASSOCIATION: (6524.1) SUBSYSTEM: Transport, Extracellular
D-glucose transport in via proton symport_fwd
N-Acetyl-D-glucosaminyldiphosphodolichol, human uterine homolog
Gamma-glutamyl hydrolase (6THF), lysosomal
GENE_ASSOCIATION: (8836.1) SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (2531.1) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (55808.1) SUBSYSTEM: O-Glycan Biosynthesis
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1) SUBSYSTEM: Nucleotides
nucleoside-diphosphate kinase (ATP:dCDP), nuclear_fwd
chondroitin sulfate E proteoglycan protease, lysosome (endosome)
GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (230.1) or (229.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (10599.1) or (28234.1) SUBSYSTEM: Transport, Extracellular
bilirubin monoglucuronide transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1) or (30.1 and 51.2 and 1962.1) or (3295.1 and 30.1 and 51.2) SUBSYSTEM: Fatty acid oxidation, peroxisome
N-acetylgalactosamine-4-sulfatase, lysosomal_bkwd
GENE_ASSOCIATION: (411.2) or (411.1) SUBSYSTEM: Chondroitin sulfate degradation
((N-acetyl-D-glucosaminyl)3-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)
GENE_ASSOCIATION: (1594.1) SUBSYSTEM: Vitamin D
dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (liver)
GENE_ASSOCIATION: SUBSYSTEM: Carnitine shuttle
transport into the mitochondria from cytosol (carnitine)
phosphatidylinositol-3,4-bisphosphate (Homo sapiens)
keratan sulfate II (core 2-linked), degradation product 3
COA transporter, endoplasmic reticulum_bkwd
GENE_ASSOCIATION: (57835.3) or (8671.1) or (57835.2) or (57835.1) or (57835.4) SUBSYSTEM: Transport, Extracellular
bicarbonate transport (Na/HCO3 1:3 cotransport)_fwd
GENE_ASSOCIATION: (6557.1) or (6558.1) SUBSYSTEM: Transport, Extracellular
mannosidase II, endoplasmic reticulum (g1m7masnC-producing)
diphosphatidylinositol tetrakisphosphate nuclear transport (diffusion)_bkwd
GENE_ASSOCIATION: (27068.4) or (27068.1) or (27068.3) or (27068.2) SUBSYSTEM: Oxidative Phosphorylation
GENE_ASSOCIATION: (93183.1) and (54965.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
GlcN-acylPI mannosyltransferase, endoplasmic reticulum
GENE_ASSOCIATION: (18.1) or (18.2) SUBSYSTEM: beta-Alanine metabolism
3-Aminopropanoate:2-oxoglutarate aminotransferase (m)_bkwd
GENE_ASSOCIATION: (7084.1) SUBSYSTEM: Nucleotides
nucleoside-diphosphate kinase (ATP:IDP), mitochondrial_bkwd
folylpolyglutamate synthetase (DHF), mitochondrial
L-Citramalyl-CoA hydro-lyase, mitochondrial_fwd
GENE_ASSOCIATION: SUBSYSTEM: C5-Branched dibasic acid metabolism
Dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase (liver)
Cyanide transport via diffusion (extracellular to cytosol)_fwd
alpha-amylase, extracellular (glygn2 -> glygn4)
GENE_ASSOCIATION: (29988.1) or (6513.1) or (6515.1) or (6514.1) or (81031.1) SUBSYSTEM: Transport, Extracellular
phosphatidylinositol 4-phosphate nuclear transport (diffusion)_bkwd
N-acetylglucosamine-6-sulfatase, lysosomal_fwd
GENE_ASSOCIATION: (2799.1) SUBSYSTEM: Keratan sulfate degradation
heparan-glucosaminide N-acetyltransferase, lysosomal
GENE_ASSOCIATION: (1559.1) or (1557.1) SUBSYSTEM: Limonene and pinene degradation
leukotriene intracellular transport_bkwd
alcohol dehydrogenase (ethanol, NADP), forward reaction
GENE_ASSOCIATION: (10327.1) or (10327.2) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (29920.1) or (65263.1) SUBSYSTEM: Urea cycle/amino group metabolism
L-serine/L-asparagine Na-dependent exchange (Ser-L in)
GENE_ASSOCIATION: (6510.1) SUBSYSTEM: Transport, Extracellular
leucine transaminase, mitochondrial_bkwd
GENE_ASSOCIATION: (376497.1) or (376497.2) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (117247.1) or (124935.1) SUBSYSTEM: Transport, Extracellular
L-phenylalanine transport via diffusion (extracellular to cytosol)_bkwd
GENE_ASSOCIATION: (6581.1) or (6582.2) or (6582.1) SUBSYSTEM: Transport, Extracellular
5-Hydroxykynurenamine:oxygen oxidoreductase(deaminating)(flavin-containing)
GENE_ASSOCIATION: (2592.1) or (2592.3) or (2592.2) SUBSYSTEM: Galactose metabolism
galactose-1-phosphate uridylyltransferase_bkwd
sialyl (2,3) sialyl (2,6) galactosylgloboside (homo sapiens)
GENE_ASSOCIATION: (6611.1) SUBSYSTEM: Urea cycle/amino group metabolism
5-diphosphatidylinositol pentakisphosphate nuclear transport (diffusion)_fwd
L-erythro-4-Hydroxyglutamate:2-oxoglutarate aminotransferase
GENE_ASSOCIATION: (2805.1) SUBSYSTEM: Arginine and Proline Metabolism
g1m7masnC endoplasmic reticulum to Golgi transport
4-aminobutyrate reversible transport in via proton symport (lysosome)_bkwd
tetrahydrofolate transport via anion exchange_fwd
GENE_ASSOCIATION: (290.1) SUBSYSTEM: Glutathione Metabolism
L-lysine transport, peroxisomal (irreversible)
GENE_ASSOCIATION: (3938.1) SUBSYSTEM: Galactose metabolism
phosphatidylinositol 4-phosphate 5-kinase, nuclear
GENE_ASSOCIATION: (27087.2) or (135152.1) or (27087.1) or (26229.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
UDP-D-glucuronate:galactosylgalactosylxylose glucuronosyltransferase, Golgi apparatus
keratan sulfate II (core 2-linked), degradation product 2
GENE_ASSOCIATION: SUBSYSTEM: Cysteine Metabolism
corticosterone intracellular transport_bkwd
GENE_ASSOCIATION: (3074.1) or (3073.1) or (3073.1 and 3074.1) SUBSYSTEM: N-Glycan Degradation
dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (uterus)
N-acetylglucosamine-6-sulfatase, lysosomal_bkwd
superoxide anion transport via diffusion (extracellular)_fwd
GENE_ASSOCIATION: (3294.1) SUBSYSTEM: Steroid Metabolism
L-ascorbate transport via facilitated diffusion_fwd
GENE_ASSOCIATION: (26266.1) SUBSYSTEM: Transport, Extracellular
sulfate transport via sodium symport_bkwd
GENE_ASSOCIATION: (84532.1) SUBSYSTEM: Propanoate Metabolism
chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 1
GENE_ASSOCIATION: (6548.1) or (6550.1) or (6549.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: SUBSYSTEM: Nucleotide Sugar Metabolism
hyaluronan transport, extracellular to lysosome
GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism
purine-nucleoside phosphorylase (Deoxyadenosine)_fwd
H transporter, endoplasmic reticulum_bkwd
aldehyde dehydrogenase (acetylaldehyde, NAD), mitochondrial
GENE_ASSOCIATION: (219.1) or (217.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
chondroitin sulfate A (GalNAc4S-GlcA), B (IdoA2S-GalNAc4S), and E (GalNAc4,6diS-GlcA), precursor 1
keratan sulfate II biosynthesis, precursor 8
keratan sulfate I, degradation product 19
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
Endomannosidase (m6masnC-producing), Golgi apparatus
glycine passive transport to mitochondria_fwd
GENE_ASSOCIATION: (6515.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2582.1) or (2582.2) SUBSYSTEM: Aminosugar Metabolism
UDP-N-acetylglucosamine 4-epimerase_bkwd
nucleoside-diphosphate kinase (ATP:dIDP), nuclear_bkwd
GENE_ASSOCIATION: SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (3074.1) or (3073.1 and 3074.1) or (3073.1) SUBSYSTEM: Keratan sulfate degradation
pyruvate reversible transport via proton symport_fwd
GENE_ASSOCIATION: (9123.1) or (9194.1) or (6566.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (1384.1) SUBSYSTEM: Carnitine shuttle
carnitine O-aceyltransferase, mitochondrial_bkwd
uridine transport in via sodium symport (1:2)
GENE_ASSOCIATION: (64078.1) SUBSYSTEM: Transport, Extracellular
Methanol transporter, endoplasmic reticulum_bkwd
Methylmalonyl-CoA decarboxylase, peroxisomal
GENE_ASSOCIATION: (23417.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
nucleoside-diphosphate kinase (ATP:dIDP), nuclear_fwd
GENE_ASSOCIATION: (26503.1) SUBSYSTEM: Transport, Lysosomal
chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 3
phosphatidylinositol N-acetylglucosaminyltransferase
omega hydroxy dodecanoate (n-C12:0) exchange
13-cis-retinoic acid transport, nuclear_fwd
N-acetylgalactosamine-4-sulfatase, lysosomal_fwd
25-hydroxyvitamin D2 transport in mitochondria
chondroitin sulfate C (GalNAc6S-GlcA) proteoglycan
GENE_ASSOCIATION: (1593.1) SUBSYSTEM: Vitamin D
lipid, flip-flop intracellular transport_bkwd
3-methyl-2-oxobutanoate mitochondrial transport via proton symport
choline phosphate intracellular transport_bkwd
chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 3
GENE_ASSOCIATION: (192134.1) SUBSYSTEM: O-Glycan Biosynthesis
Core 3 beta-GlcNAc-transferase, Golgi apparatus
GENE_ASSOCIATION: (26301.1) SUBSYSTEM: Sphingolipid Metabolism
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
GENE_ASSOCIATION: (5230.1) or (348477.1) or (5232.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included) 1
GENE_ASSOCIATION: (2525.1) SUBSYSTEM: Blood Group Biosynthesis
GENE_ASSOCIATION: (2584.1) or (2585.2) or (2585.1) SUBSYSTEM: Galactose metabolism
GENE_ASSOCIATION: (29929.1) SUBSYSTEM: N-Glycan Biosynthesis
dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase (uterus)
D-galactose transport via proton symport_bkwd
GENE_ASSOCIATION: (2766.1) or (51292.1) or (51292.3) or (51292.2) SUBSYSTEM: Nucleotides
Beta oxidation of med/long chain fatty acid
GENE_ASSOCIATION: (26.1) or (314.1) or (8639.1) or (314.2) SUBSYSTEM: Histidine Metabolism
N-Methylhistamine:oxygen oxidoreductase (deaminating)
CO2 transport (diffusion), mitochondrial_bkwd
UDP-GlcNAc:dolichol-phosphate GlcNAc phosphotransferase (uterus)
GENE_ASSOCIATION: (1798.1) or (1798.2) SUBSYSTEM: N-Glycan Biosynthesis
GENE_ASSOCIATION: (4124.1) or (4122.1) SUBSYSTEM: N-Glycan Biosynthesis
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
13-cis-4-oxo-retinoic acid isomerase_fwd
carbamoyl phosphate transport, endoplasmic reticulum_bkwd
GENE_ASSOCIATION: (3162.1) or (3163.1) SUBSYSTEM: Heme Degradation
GENE_ASSOCIATION: (4942.1) SUBSYSTEM: Urea cycle/amino group metabolism
ornithine transaminase reversible (m)_fwd
dephospho-CoA transport from lysosome via diffusion_fwd
GENE_ASSOCIATION: (5236.1) or (55276.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (790.1) SUBSYSTEM: Pyrimidine Biosynthesis
GENE_ASSOCIATION: (2571.1) or (2571.2) SUBSYSTEM: beta-Alanine metabolism
keratan sulfate I, degradation product 6
uronolactonase, endoplasmic reticulum_fwd
GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
testosterone intracellular transport_bkwd
N-acetyl-galactosamine intracellular transport_bkwd
GENE_ASSOCIATION: (6309.1) SUBSYSTEM: Cholesterol Metabolism
nucleoside-diphosphate kinase (ATP:CDP), mitochondrial_bkwd
carnitine-propcarnitine carrier, peroxisomal
GENE_ASSOCIATION: (55268.1) SUBSYSTEM: Butanoate Metabolism
3-hydroxybutyryl-CoA dehydratase, mitochondrial_fwd
GENE_ASSOCIATION: (2180.1) or (2181.2) or (2181.1) SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (6342.1) SUBSYSTEM: Bile Acid Biosynthesis
nucleoside-diphosphate kinase (ATP:dCDP)_bkwd
GENE_ASSOCIATION: (112611.1) or (98.1) or (97.2) or (97.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
nucleoside-diphosphate kinase (ATP:dGDP)_fwd
GENE_ASSOCIATION: (8501.1) or (124935.1) SUBSYSTEM: Transport, Extracellular
L-isoleucine transport via diffusion (extracellular to cytosol)_fwd
GENE_ASSOCIATION: (6648.1) SUBSYSTEM: ROS Detoxification
Phosphatidylserine synthase homo sapiens_fwd
GENE_ASSOCIATION: (9791.1) SUBSYSTEM: Glycerophospholipid Metabolism
L-cysteine/glycine reversible exchanger_fwd
C-3 sterol dehydrogenase (4-methylzymosterol)
GENE_ASSOCIATION: (50814.1) SUBSYSTEM: Cholesterol Metabolism
chondroitin 6-sulfotransferase, Golgi apparatus
GENE_ASSOCIATION: (9469.1) or (56548.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
GENE_ASSOCIATION: (5743.1) or (5742.1) SUBSYSTEM: Eicosanoid Metabolism
galgalgalthcrm hs intracellular transport_fwd
H2O endoplasmic reticulum transport_bkwd
acnacngalgbside hs intracellular transport_fwd
retinyl ester hydrolase (9-cis), extracellular
phosphoribosylaminoimidazole carboxylase_bkwd
GENE_ASSOCIATION: (10606.1) SUBSYSTEM: IMP Biosynthesis
GENE_ASSOCIATION: (58510.1) SUBSYSTEM: Arginine and Proline Metabolism
chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4
GENE_ASSOCIATION: (384.1) SUBSYSTEM: Urea cycle/amino group metabolism
Hydroxymethylglutaryl-CoA reversible peroxisomal transport_bkwd
GENE_ASSOCIATION: (6715.1) or (6716.1) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (6554.1) or (6555.1) SUBSYSTEM: Transport, Extracellular
cholate transport via sodium cotransport
GENE_ASSOCIATION: (6509.1) or (6510.1) SUBSYSTEM: Transport, Extracellular
L-serine/L-cysteine Na-dependent exchange (Cys-L in)
folylpolyglutamate synthetase (10fthf), mitochondrial
inosine facilated transport from lysosome_bkwd
1-acylglycerol-3-phosphate O-acyltransferase 1
GENE_ASSOCIATION: (5740.1) SUBSYSTEM: Eicosanoid Metabolism
lactose transport from cytosol to lysosome (via autophagocytosis)
GENE_ASSOCIATION: (6785.1) SUBSYSTEM: Fatty acid elongation
Fumarate:thiosulfate antiport, mitochondrial_bkwd
GENE_ASSOCIATION: (1589.1) SUBSYSTEM: Steroid Metabolism
keratan sulfate II biosynthesis, precursor 5
GENE_ASSOCIATION: (8884.1) SUBSYSTEM: Transport, Extracellular
glycine-cleavage system (lipoamide) irreversible, mitochondrial
keratan sulfate I, degradation product 34
bicarbonate transport (Na/HCO3 1:2 cotransport)_fwd
GENE_ASSOCIATION: SUBSYSTEM: NAD Metabolism
L-cysteine/L-glutamine Na-dependent exchange (Cys-L in)
nicotinate-nucleotide adenylyltransferase, mitochondrial
GENE_ASSOCIATION: (349565.1) SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (23563.2) or (9435.1) or (23563.1) or (10164.1) or (4166.1) SUBSYSTEM: Keratan sulfate biosynthesis
galactose/N-acetylglucosamine 6-O-sulfotransferase, Golgi apparatus
GENE_ASSOCIATION: (11212.1) SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (10998.1) SUBSYSTEM: Transport, Extracellular
inositol 1,4-bisphosphate nuclear transport (diffusion)_fwd
GENE_ASSOCIATION: (54576.1) or (54575.1) SUBSYSTEM: Vitamin A Metabolism
UDP-glucuronosyltransferase 1-10 precursor, microsomal (13-cis)
GENE_ASSOCIATION: (7264.1) SUBSYSTEM: Fructose and Mannose Metabolism
keratan sulfate I biosynthesis, precursor 25
GENE_ASSOCIATION: (5372.1) or (55276.1) or (5373.1) SUBSYSTEM: Fructose and Mannose Metabolism
formaldehyde transport via diffusion (lysosomall)_bkwd
GENE_ASSOCIATION: (51477.1) SUBSYSTEM: Inositol Phosphate Metabolism
Technion - Israel Institute of Technology
nucleoside-diphosphate kinase (ATP:dTDP), mitochondrial_fwd
GENE_ASSOCIATION: (28.1) SUBSYSTEM: Blood Group Biosynthesis
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
GENE_ASSOCIATION: (1891.1) or (1962.1) SUBSYSTEM: Limonene and pinene degradation
cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (x)_fwd
Nicotinamide adenine dinucleotide phosphate - reduced
guanylate kinase (GMP:ATP), mitochondrial_bkwd
GENE_ASSOCIATION: SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (875.1) SUBSYSTEM: Selenoamino acid metabolism
hydroxylated testosterone transport_bkwd
GENE_ASSOCIATION: (55163.1) SUBSYSTEM: Vitamin B6 Metabolism
GENE_ASSOCIATION: (222.1) or (220.1) or (221.1) or (218.1) SUBSYSTEM: Tyrosine metabolism
4-Hydroxyphenylacetaldehyde:NADP+ oxidoreductase_fwd
GENE_ASSOCIATION: (64816.1) or (64816.3) or (64816.2) SUBSYSTEM: Steroid Metabolism
Diacylglycerol phosphate kinase (homo sapiens)_bkwd
GENE_ASSOCIATION: (8525.1) or (9162.1) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (3284.1) SUBSYSTEM: Steroid Metabolism
chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 6
Inorganic triphosphate transport through nuclear pore_bkwd
GENE_ASSOCIATION: (3156.1) SUBSYSTEM: Cholesterol Metabolism
Hydroxymethylglutaryl CoA reductase (ir)
GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) SUBSYSTEM: Chondroitin sulfate degradation
N-acetylgalactosamine-6-sulfatase, lysosomal_bkwd
dNAD transport, nuclear trhough pore_bkwd
GENE_ASSOCIATION: (954.2) or (954.1) or (953.1) or (956.1) or (955.1) or (957.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (6483.1) SUBSYSTEM: Sphingolipid Metabolism
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase, Golgi apparatus
GENE_ASSOCIATION: SUBSYSTEM: Biotin Metabolism
adenine reversible transport, cytosol_bkwd
GENE_ASSOCIATION: (2593.1) or (2593.2) SUBSYSTEM: Urea cycle/amino group metabolism
guanidinoacetate N-methyltransferase (c)_fwd
(R)-3-Hydroxybutanoate transport via H+ symport
Etiocholan-3alpha-ol-17-one 3-glucuronide exchange
GENE_ASSOCIATION: SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: SUBSYSTEM: Histidine Metabolism
GENE_ASSOCIATION: (2519.1) SUBSYSTEM: N-Glycan Degradation
GENE_ASSOCIATION: (1644.1) SUBSYSTEM: Tyrosine metabolism
UDPglucuronate uridine-monophosphohydrolase
GENE_ASSOCIATION: (55343.1) SUBSYSTEM: Transport, Golgi Apparatus
GDPFuc Golgi transport via CMP antiport_bkwd
GENE_ASSOCIATION: (2194.1) SUBSYSTEM: Fatty Acid Metabolism
guanosine facilated transport in mitochondria_bkwd
GENE_ASSOCIATION: (10380.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (84532.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
nucleoside-diphosphate kinase (ATP:dUDP), mitochondrial_fwd
phosphatidylinositol 4-phosphate 3-kinase
superoxide anion transport via diffusion (extracellular)_bkwd
carnitine-acetylcarnitine carrier, peroxisomal
GENE_ASSOCIATION: (113189.1) or (50515.1) or (166012.1) or (55501.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
chondroitin 4-sulfotransferase, Golgi apparatus
galgluside hs intracellular transport_bkwd
(alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
sphingosylphosphorylcholine transport (diffusion)_fwd
Core 5 alpha-GalNAc-transferase, Golgi apparatus
hydroxyphenylacetate transport via diffusion_fwd
GENE_ASSOCIATION: (53.1) SUBSYSTEM: Nucleic acid degradation
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, Golgi apparatus
GENE_ASSOCIATION: (6526.1) or (6523.1) or (6528.1) SUBSYSTEM: Transport, Extracellular
dehydroascorbate transport (uniport)_fwd
GENE_ASSOCIATION: (6515.1) or (6513.1) or (6517.1) SUBSYSTEM: Transport, Extracellular
4-oxo-retinoic acid transport, Nuclear_fwd
GENE_ASSOCIATION: SUBSYSTEM: Sphingolipid Metabolism
L-alanine/L-threonine Na-dependent exchange (Thr-L in)
GENE_ASSOCIATION: (2805.1) SUBSYSTEM: Phenylalanine metabolism
keratan sulfate I, degradation product 7
sulfate transport via oxalate countertransport (2:1)
GENE_ASSOCIATION: (65010.1) or (65010.3) or (65010.2) SUBSYSTEM: Transport, Extracellular
nucleoside-diphosphate kinase (ATP:IDP), nuclear_bkwd
Gamma-glutamyl hydrolase (10FTHF6GLU), extracellular
Dehydrodolichol diphosphate, human uterine homolog
deoxyuridine kinase (ATP:Deoxyuridine), mitochondrial
L-arabinoase extracellular transport_bkwd
nucleoside-diphosphate kinase (ATP:UDP), mitochondrial_bkwd
2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating) (mitochondria)
Dolichyl beta-D-glucosyl phosphate, human uterine homolog
inositol 1-phosphate nuclear transport (diffusion)_bkwd
GENE_ASSOCIATION: (1644.1) SUBSYSTEM: Tryptophan metabolism
Proline transport (sodium symport) (2:1)_bkwd
GENE_ASSOCIATION: (6534.1) SUBSYSTEM: Transport, Extracellular
fatty-acid--CoA ligase (hexadecenoate)_fwd
N-acetylglucosamine-3-sulfatase, lysosomal_bkwd
GENE_ASSOCIATION: (1586.1) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Glutamate metabolism
1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
L-alanine reversible transport via proton symport_bkwd
GENE_ASSOCIATION: (206358.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: SUBSYSTEM: Miscellaneous
phosphatidylinositol-5-phosphate 3-kinase
bicarbonate transport (Cl-/HCO3- exchange)_fwd
GENE_ASSOCIATION: (6522.1) or (83697.1) or (6521.1) or (6508.2) or (6508.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (239.1) SUBSYSTEM: Eicosanoid Metabolism
arginine mitochondrial transport via ornithine carrier_bkwd
glycophosphatidylinositol (GPI) signal sequence (C-terminal peptide)
GENE_ASSOCIATION: (8564.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (231.1) or (10327.2) or (10327.1) SUBSYSTEM: Galactose metabolism
GENE_ASSOCIATION: (64080.1) SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (6472.1) SUBSYSTEM: Lysine Metabolism
glycine hydroxymethyltransferase, mitochondrial
GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (7298.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (6480.1) or (6480.3) or (6480.2) SUBSYSTEM: N-Glycan Biosynthesis
beta-galactoside alpha-2,6-sialyltransferase
GENE_ASSOCIATION: (5834.1) or (5836.1) or (5837.1) SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (95.1) SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (197257.1) or (197257.2) SUBSYSTEM: Pyruvate Metabolism
purine-nucleoside phosphorylase (Deoxyguanosine)_fwd
L-threonine/L-asparagine Na-dependent exchange (Thr-L in)
glycine reversible transport via sodium and chloride symport (3:1:1)_bkwd
GENE_ASSOCIATION: (9152.1) SUBSYSTEM: Transport, Extracellular
fatty acyl-CoA desaturase (n-C18:1CoA -> n-C18:2CoA)
Se-adenosyl-seleno-L-homocysteine nuclear transport_fwd
GENE_ASSOCIATION: SUBSYSTEM: Selenoamino acid metabolism
GENE_ASSOCIATION: SUBSYSTEM: Arginine and Proline Metabolism
L-1-Pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-Hydroxyglutamate semialdehyde, mitochondrial_bkwd
Phosphatidylcholine (homo sapiens) exchange
GENE_ASSOCIATION: (4128.1) or (4129.1) SUBSYSTEM: Arginine and Proline Metabolism
N-acetylputrescine: oxygen oxireductase (deaminating)
GENE_ASSOCIATION: (23498.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (6489.1) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (1583.1) SUBSYSTEM: Steroid Metabolism
Cytochrome P450 11A1, mitochondrial [Precursor]
dimethylglycine transport via diffusion (cytosol to mitochondria)_fwd
5,6,7,8-Tetrahydrofolate transport, diffusion, lysosomal_fwd
GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
D-Lactaldehyde:NAD+ oxidoreductase (glutathione-formylating)_fwd
GENE_ASSOCIATION: (6561.1) SUBSYSTEM: Transport, Extracellular
thiosulfate transport via sodium symport_bkwd
GENE_ASSOCIATION: (2597.1) or (26330.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
glyceraldehyde-3-phosphate dehydrogenase_fwd
GENE_ASSOCIATION: (34.1) SUBSYSTEM: Fatty acid oxidation
S-Adenosyl-L-methionine intracellular diffusion_bkwd
(Gal)3 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1
GENE_ASSOCIATION: (57678.1) SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (8402.1) SUBSYSTEM: Transport, Mitochondrial
alpha-ketoglutarate/malate transporter_fwd
GENE_ASSOCIATION: (686.1) SUBSYSTEM: Biotin Metabolism
keratan sulfate II (core 2-linked), degradation product 8
NADPH transporter, endoplasmic reticulum
Gamma-glutamyl hydrolase (6THF), extracellular
chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S) proteoglycan exchange
GENE_ASSOCIATION: (26275.1) or (26275.2) SUBSYSTEM: beta-Alanine metabolism
3-hydroxyisobutyryl-Coenzyme A hydrolase
(alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
GENE_ASSOCIATION: (9380.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (5264.1) SUBSYSTEM: Fatty acid oxidation, peroxisome
3 beta-hydroxysteroid dehydrogenase type 1
Thiamine monophosphate transport, mitochondrial_fwd
glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})
GENE_ASSOCIATION: (79178.1) SUBSYSTEM: Thiamine Metabolism
estrone 3-sulfate transport via bicarbonate countertransport_bkwd
galactose transport via sodium symport_fwd
nucleoside-diphosphate kinase (ATP:dTDP), nuclear_fwd
GENE_ASSOCIATION: (9942.1) SUBSYSTEM: Pentose and Glucuronate Interconversions
GENE_ASSOCIATION: (4051.1) or (8529.1) or (66002.1) SUBSYSTEM: Eicosanoid Metabolism
GENE_ASSOCIATION: (39.1) SUBSYSTEM: Cholesterol Metabolism
acetyl-CoA C-acetyltransferase, mitochondrial
GENE_ASSOCIATION: (9197.1) SUBSYSTEM: Transport, Extracellular
O2 transport, endoplasmic reticulum_bkwd
citrulline mitochondrial transport via proton antiport_fwd
folate transport via anion exchange_bkwd
sialyl (1,3) sialyl (2,6) galactosylgloboside (homo sapiens)
L-valine transport via diffusion (extracellular to cytosol)_fwd
GENE_ASSOCIATION: SUBSYSTEM: Pyrimidine Catabolism
D-3-Amino-isobutanoate:pyruvate aminotransferase, mitochondrial_bkwd
GENE_ASSOCIATION: (4668.1) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (1572.1) SUBSYSTEM: CYP Metabolism
L-alanine/glutamine reversible exchange_fwd
3,4-Dihydroxy-L-phenylalanine transport_fwd
GENE_ASSOCIATION: (117247.1) SUBSYSTEM: Transport, Extracellular
galgluside hs intracellular transport_fwd
GENE_ASSOCIATION: (34.1) or (35.1) SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (29988.1) or (6514.1) or (155184.1) or (6518.1) or (66035.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (8309.1) SUBSYSTEM: Bile Acid Biosynthesis
acyl-Coenzyme A oxidase 2, branched chain
GENE_ASSOCIATION: (140679.1) SUBSYSTEM: Transport, Extracellular
GABA secretion via secretory vesicle (ATP driven)
GENE_ASSOCIATION: (1584.1) SUBSYSTEM: Steroid Metabolism
L-sulfolactate dehydrogenase (NAD+)_bkwd
GENE_ASSOCIATION: (212.1) or (23464.1) or (211.2) or (211.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (11254.1) SUBSYSTEM: Transport, Extracellular
L-tyrosine transport in via sodium symport
GENE_ASSOCIATION: (5321.1) or (1178.1) or (29124.1) SUBSYSTEM: Glycerophospholipid Metabolism
Pyridoxamine 5'-phosphate transport via diffusion, mitochondrial_fwd
mannosyl-oligosaccharide 1,2-alpha-mannosidase, Golgi apparatus
GENE_ASSOCIATION: (57134.1) or (10905.1) or (4121.1) SUBSYSTEM: N-Glycan Biosynthesis
Se-adenosyl-seleno-L-methionine nuclear transport_bkwd
GENE_ASSOCIATION: (4047.1) SUBSYSTEM: Cholesterol Metabolism
beta-galactoside alpha-2,3-sialyltransferase (T antigen)
GENE_ASSOCIATION: (6482.1) or (6482.2) SUBSYSTEM: O-Glycan Biosynthesis
docosa-4,7,10,13,16-pentaenoic acid (n-6)
GENE_ASSOCIATION: (5973.1) SUBSYSTEM: Aminosugar Metabolism
nucleoside-diphosphate kinase (ATP:UDP)_fwd
GENE_ASSOCIATION: (84912.1) SUBSYSTEM: Transport, Golgi Apparatus
UDP-Xyl Golgi transport via CMP antiport_bkwd
5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)
GENE_ASSOCIATION: (26873.1) SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (9487.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
N-acetylglucosaminylphosphatidylinositol deacetylase
GENE_ASSOCIATION: (162466.1) SUBSYSTEM: Glycerophospholipid Metabolism
Cytidine facilated transport from lysosome_bkwd
Nalpha-(beta-alanyl)-L-histidine hydrolase IR
GENE_ASSOCIATION: (84735.1) SUBSYSTEM: beta-Alanine metabolism
GENE_ASSOCIATION: (4199.1) SUBSYSTEM: Pyruvate Metabolism
Endomannosidase (glc2man-producing), Golgi apparatus
GENE_ASSOCIATION: (10400.2) or (10400.1) or (10400.3) SUBSYSTEM: Glycerophospholipid Metabolism
phosphatidylethanolamine N-methyltransferase
GENE_ASSOCIATION: (6582.1) or (6584.1) or (6582.2) SUBSYSTEM: Transport, Extracellular
holocarboxylase synthestase (biotin protein ligase), mitochondrial
GENE_ASSOCIATION: (3141.1) SUBSYSTEM: Biotin Metabolism
Dolichyl phosphate D-mannose, human uterine homolog
GENE_ASSOCIATION: (6530.1) or (6531.1) SUBSYSTEM: Transport, Extracellular
Dopamine reversible transport in via sodium symport (1:2)_bkwd
sphingomyelin intracellular transport_bkwd
GENE_ASSOCIATION: (57194.1) SUBSYSTEM: Transport, Mitochondrial
5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase
GENE_ASSOCIATION: (117283.1) or (9807.2) or (9807.1) SUBSYSTEM: Inositol Phosphate Metabolism
testicular 17-beta-hydroxysteroid dehydrogenase_fwd
GENE_ASSOCIATION: (3292.1) or (7923.1) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (5130.1) or (9468.1) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (205.3) or (205.1) or (204.1) or (204.3) or (204.2) or (205.2) SUBSYSTEM: Nucleotides
(dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (H6)
L-methionine transport via diffusion (extracellular to cytosol)_fwd
bile acid Coenzyme A: amino acid N-acyltransferase
GENE_ASSOCIATION: (570.1) SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (6888.1) SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (55902.1) or (55902.2) SUBSYSTEM: Propanoate Metabolism
Phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase
keratan sulfate I, degradation product 2
inositol hexakisphosphate nuclear transport (diffusion)_bkwd
GENE_ASSOCIATION: (376497.2) or (10999.1) or (376497.1) or (11000.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (7498.1) SUBSYSTEM: Purine Catabolism
cytidylate kinase (CMP,dCTP),nuclear_bkwd
Norepinephrine reversible transport in via sodium symport (1:2)_bkwd
GENE_ASSOCIATION: (2595.1) SUBSYSTEM: Starch and Sucrose Metabolism
purine-nucleoside phosphorylase (Adenosine)_bkwd
GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (6513.1) or (6517.1) or (6514.1) SUBSYSTEM: Transport, Extracellular
acetate reversible transport via proton symport_bkwd
GENE_ASSOCIATION: (8424.1) SUBSYSTEM: Lysine Metabolism
4-Trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
GENE_ASSOCIATION: (586.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 4
GENE_ASSOCIATION: (23483.1) SUBSYSTEM: Nucleotide Sugar Metabolism
histone-lysine N-methyltransferase, nuclear
Biotin reversible transport via proton symport_bkwd
GENE_ASSOCIATION: (6566.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (1120.2) or (1119.1) or (1120.1) or (1119.2) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (159.1) or (122622.1) or (122622.2) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (2538.1) or (57818.1) or (92579.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
Carbamoyl phosphate phosphotransferase, endoplasmic reticulum
GENE_ASSOCIATION: (3990.1) or (9388.1) or (5407.1) or (8513.1) or (5408.1) or (5406.1) SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (34.1) or (34.1) or (35.1) or (35.1) SUBSYSTEM: Fatty acid oxidation
inosine facilated transport in mitochondria_fwd
Se-adenosyl-seleno-L-homocysteine nuclear transport_bkwd
alkyl acyl glycerophosphoethanolamine desaturase
nucleoside-diphosphate kinase (ATP:dTDP)_fwd
5-Hydroxytryptamine:oxygen 2,3-dioxygenase (indole-decyclizing)
GENE_ASSOCIATION: (3620.1) SUBSYSTEM: Tryptophan metabolism
keratan sulfate II biosynthesis, precursor 6
GENE_ASSOCIATION: (50487.1) SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (2747.1) or (2746.1) SUBSYSTEM: Glutamate metabolism
glutamate dehydrogenase (NADP), mitochondrial_fwd
GENE_ASSOCIATION: (26035.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
heparosan-N-sulfate-glucuronate 5-epimerase
GENE_ASSOCIATION: (4357.1) SUBSYSTEM: Cysteine Metabolism
GENE_ASSOCIATION: (10026.1) and (8733.1) and (128869.1) and (94005.1) and (51604.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
GENE_ASSOCIATION: (2539.1) SUBSYSTEM: Pentose Phosphate Pathway
D-Serine/Glutamine reversible exchange_fwd
metanephrine secretion via secretory vesicle (ATP driven)
Lecithin retinol acyltransferase (9-cis)
GENE_ASSOCIATION: (9245.1) or (2650.1) or (51301.1) SUBSYSTEM: O-Glycan Biosynthesis
Core 2 acetylglucosaminyltransferase, Golgi apparatus
(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)
Itaconate--CoA ligase (GDP-forming), mitochondrial_fwd
2,6 dimethylheptanoyl carnitine exchange
GENE_ASSOCIATION: (39.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (5959.1) SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (30.1) SUBSYSTEM: Fatty Acid Metabolism
acetyl-CoA acyltransferase (tetradecanoyl-CoA), peroxisomal
NAD transport, nuclear through pores_bkwd
L-glutamate 5-semialdehyde dehydratase, reversible, mitochondrial_fwd
GENE_ASSOCIATION: (1891.1) or (1962.1) SUBSYSTEM: Tryptophan metabolism
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA) (perioxisome)_bkwd
GENE_ASSOCIATION: (80150.1) SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (10087.1) SUBSYSTEM: Transport, Golgi Apparatus
AMP transporter, endoplasmic reticulum_bkwd
phosphatidylinositol 4,5-bisphosphate nuclear transport (diffusion)_fwd
GENE_ASSOCIATION: (57134.1) SUBSYSTEM: N-Glycan Biosynthesis
GENE_ASSOCIATION: (4522.1) or (286297.1) SUBSYSTEM: Folate Metabolism
keratan sulfate I biosynthesis, precursor 10
GENE_ASSOCIATION: (5832.1) SUBSYSTEM: Urea cycle/amino group metabolism
N-acetyl-g-glutamyl-phosphate reductase, irreversible, mitochondrial
acetyl-CoA acyltransferase (tetracosanoyl-CoA), peroxisomal
GENE_ASSOCIATION: (2628.1) SUBSYSTEM: Urea cycle/amino group metabolism
3-mercaptolactate-cysteine disulfide exchange
D-alanine transport via proton symport (lysosome)_bkwd
GENE_ASSOCIATION: SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
GENE_ASSOCIATION: (8574.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (1558.1) or (1558.2) SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (4129.1) or (26.1) or (4128.1) or (314.1) or (314.2) SUBSYSTEM: Tryptophan metabolism
Tryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)
Glycolipid 1,2-alpha-D-mannosyltransferase (liver)
phosphatidylinositol-4,5-bisphosphate 5-phosphatase, nuclear
GENE_ASSOCIATION: (54575.1) or (54490.1) or (54576.1) SUBSYSTEM: Steroid Metabolism
UDPglucose--hexose-1-phosphate uridylyltransferase_bkwd
glycogen, structure 3 (glycogenin-7[1,4-Glc])
Diphosphate transporter, endoplasmic reticulum_bkwd
keratan sulfate II (core 2-linked), degradation product 6
Xylitol transport via passive diffusion_bkwd
L-methionine transport via diffusion (extracellular to cytosol)_bkwd
GENE_ASSOCIATION: (8760.1) SUBSYSTEM: Glycerophospholipid Metabolism
ethanolamine-phosphate cytidylyltransferase
GENE_ASSOCIATION: (5833.1) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (56052.1) SUBSYSTEM: N-Glycan Biosynthesis
GDPmannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase (liver)
(alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
GENE_ASSOCIATION: (1854.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (2131.1 and 2132.1) or (2131.1 and 2132.2) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 30.1 and 1962.1) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) SUBSYSTEM: Fatty acid oxidation, peroxisome
heptadecanoate transport into the mitochondria
pyruvate mitochondrial transport via proton symport_bkwd
GENE_ASSOCIATION: (6822.1) or (6820.2) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (3157.1) or (3157.2) SUBSYSTEM: Cholesterol Metabolism
Gamma-glutamyl hydrolase (5DHF), lysosomal
GENE_ASSOCIATION: (5728.1) SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, nuclear
methenyltetrahydrifikate cyclohydrolase, mitochondrial_bkwd
GENE_ASSOCIATION: (25902.1) or (10797.1) SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (43.1) or (43.2) SUBSYSTEM: Glycerophospholipid Metabolism
beta-galactoside alpha-2,3-sialyltransferase (complex N-glycan)
uridine facilated transport in mitochondria_bkwd
GENE_ASSOCIATION: SUBSYSTEM: Heme Biosynthesis
5-Aminolevulinate mitochondrial transport_fwd
GENE_ASSOCIATION: (7371.1) or (83549.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (4524.1) SUBSYSTEM: Folate Metabolism
5,10-methylenetetrahydrofolatereductase (NADPH)
GENE_ASSOCIATION: (7355.1) SUBSYSTEM: Transport, Golgi Apparatus
UDP-GalNAc Golgi transport via CMP antiport_bkwd
GENE_ASSOCIATION: (79896.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (84920.1) SUBSYSTEM: N-Glycan Biosynthesis
Dolichyl beta-D-glucosyl phosphate, human liver homolog
GENE_ASSOCIATION: (6649.1) SUBSYSTEM: ROS Detoxification
25-hydroxyvitamin D3 transport in cytoplasm
GENE_ASSOCIATION: (8228.1) SUBSYSTEM: Vitamin A Metabolism
glucosyl-(alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
GENE_ASSOCIATION: (6578.1) SUBSYSTEM: Transport, Extracellular
prostaglandin transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: SUBSYSTEM: Alkaloid biosynthesis II
nucleoside-diphosphate kinase (ATP:dUDP), mitochondrial_bkwd
retinol dehydrogenase (11-cis,NADPH)_fwd
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
GENE_ASSOCIATION: (27232.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (3612.1) or (3613.1) SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (8566.1) SUBSYSTEM: Vitamin B6 Metabolism
deoxycytidine transport via diffusion_bkwd
GENE_ASSOCIATION: (411.1) or (411.2) SUBSYSTEM: Chondroitin sulfate degradation
keratan sulfate I biosynthesis, precursor 15
L-cysteine transport via diffusion (extracellular to cytosol)_bkwd
GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (1638.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (10026.1) and (8733.1) and (128869.1) and (94005.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
L-threonine/glycine reversible exchange_fwd
testosterone intracellular transport_fwd
phosphatidylinositol 3-kinase, endoplasmic reticulum
GENE_ASSOCIATION: (5287.1) SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 3295.1 and 30.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) SUBSYSTEM: Fatty acid oxidation, peroxisome
thymidine facilated transport from lysosome_bkwd
S-Adenosyl-L-methionine:catechol O-methyltransferase
GENE_ASSOCIATION: (1312.1) or (118881.1) or (1312.2) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (22934.1) SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (10396.1) or (57194.1) SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: (4128.1) or (4129.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (1892.1) or (3030.1) and (3032.1) or (549.1) SUBSYSTEM: beta-Alanine metabolism
GENE_ASSOCIATION: (3418.1) SUBSYSTEM: Citric Acid Cycle
3-hydroxybutyryl-CoA dehydratase, mitochondrial_bkwd
(N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)
L-3-aminoisobutyrate transaminase, mitochondrial_bkwd
dehydroascorbate transport (uniport)_bkwd
GENE_ASSOCIATION: (9957.1) or (9951.1) or (222537.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
heparin-glucosamine 3-O-sulfotransferase
GENE_ASSOCIATION: (2687.1) SUBSYSTEM: Eicosanoid Metabolism
Methylmalonyl-CoA decarboxylase, mitochondrial
N-acetyl-galactosamine intracellular transport_fwd
GENE_ASSOCIATION: (11181.1) SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (23169.1) SUBSYSTEM: Transport, Endoplasmic Reticular
UDPGlcA endoplasmic reticulum transport via UMP antiport_bkwd
GENE_ASSOCIATION: (1610.1) SUBSYSTEM: D-alanine metabolism
nicotinate-nucleotide adenylyltransferase
GENE_ASSOCIATION: (5167.1) or (5169.1) or (5168.1) SUBSYSTEM: NAD Metabolism
beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human liver homolog
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase, nuclear
L-leucine transport via diffusion (extracellular to cytosol)_fwd
2,3-dioxo-L-gulonate:hydrogen peroxide oxireductase
(Gal)4 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1 exchange
3-sulfinopyruvate hydrolase (spotaneous reaction), mitochondrial
1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)
GENE_ASSOCIATION: (8802.1 and 8801.1) SUBSYSTEM: Citric Acid Cycle
Succinate--CoA ligase (GDP-forming)_bkwd
L-arabinoase extracellular transport_fwd
protein-linked asparagine residue (N-glycosylation site)
keratan sulfate I biosynthesis, precursor 5
(alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
UDP-Glc Golgi transport via CMP antiport_fwd
GENE_ASSOCIATION: (23443.1) or (84912.1) or (11046.1) SUBSYSTEM: Transport, Golgi Apparatus
GENE_ASSOCIATION: (9061.1) or (9060.1) SUBSYSTEM: Selenoamino acid metabolism
GENE_ASSOCIATION: (2184.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (51166.1) or (883.1) or (51166.2) SUBSYSTEM: Tryptophan metabolism
3-Hydroxy-L-kynurenine:2-oxoglutarate aminotransferase
Acetoacetate mitochondrial transport via H+ symport_fwd
D-glucurono-6,3-lactone transport, endoplasmic reticulum_bkwd
keratan sulfate II (core 4) transport, extracellular to lysosome
keratan sulfate II (core 2-linked), degradation product 7
GENE_ASSOCIATION: (9653.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
Phosphocreatine transport to/from mitochondria via diffusion
pantetheine-phosphate adenylyltransferase_fwd
holocarboxylase synthestase (biotin protein ligase)
guanidinoacetate N-methyltransferase (c)_bkwd
T4 transport via bicarbonate countertransport_fwd
GENE_ASSOCIATION: (53919.1) or (6579.1) or (28231.1) or (10599.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (60559.1) and (28972.1) and (90701.1) and (9789.1) and (23478.1) SUBSYSTEM: Lysine Metabolism
protein lysine peptidase (endoplasmic reticulum)
11-deoxycortisol intracellular transport_bkwd
chondroitin sulfate D (GlcNAc6S-GlcA2S) proteoglycan
GENE_ASSOCIATION: (7263.1) SUBSYSTEM: Cysteine Metabolism
Cyanide sulfurtransferase, mitochondrial
glycine reversible transport via proton symport_fwd
cytidylate kinase (CMP,UTP),nuclear_bkwd
GENE_ASSOCIATION: (3073.1) or (3073.1 and 3074.1) or (3074.1) SUBSYSTEM: Chondroitin sulfate degradation
uridine facilated transport in cytosol_bkwd
chloride transport via oxalate countertransport (2:1)
GENE_ASSOCIATION: (5226.1) SUBSYSTEM: Pentose Phosphate Pathway
(N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)
GENE_ASSOCIATION: (6716.1) or (6715.1) SUBSYSTEM: Steroid Metabolism
Malate:sulfite antiport, mitochondrial_fwd
GENE_ASSOCIATION: (132.1) or (132.2) SUBSYSTEM: Nucleotides
carbamoyl-phosphate synthase (ammonia) (mitochondria
GENE_ASSOCIATION: (1373.1) or (1373.2) SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (3423.1) or (3423.2) SUBSYSTEM: Heparan sulfate degradation
GENE_ASSOCIATION: (3242.1) SUBSYSTEM: Tyrosine metabolism
4-Hydroxyphenylpyruvate:oxygen oxidoreductase
ethanol reversible peroxisomal transport_bkwd
GENE_ASSOCIATION: (28231.1) or (6579.1) or (28234.1) or (10599.1) SUBSYSTEM: Transport, Extracellular
taurocholate transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: (11343.1) or (11343.2) SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (4507.1) SUBSYSTEM: Arginine and Proline Metabolism
cytidylate kinase (CMP,dGTP),nuclear_fwd
deoyguanosine transport in mitochondria_bkwd
5-glutamyl-10FTHF transport, mitochondrial
Nicotinamide adenine dinucleotide - reduced
GENE_ASSOCIATION: (10423.1) or (10423.2) SUBSYSTEM: Glycerophospholipid Metabolism
phosphatidylinositol synthase (Homo sapiens)_fwd
1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)
GENE_ASSOCIATION: (79814.1) SUBSYSTEM: Arginine and Proline Metabolism
GENE_ASSOCIATION: (1644.1) or (3067.1) SUBSYSTEM: Histidine Metabolism
phosphatidylinositol-3,5-bisphosphate 3-phosphatase
GENE_ASSOCIATION: (8897.1) or (8897.3) or (8897.2) SUBSYSTEM: Inositol Phosphate Metabolism
13-cis-retinoic acid transport, nuclear_bkwd
GENE_ASSOCIATION: (353.1) SUBSYSTEM: Salvage Pathway
sialytransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialytransferase) F
GENE_ASSOCIATION: (30815.1) SUBSYSTEM: Sphingolipid Metabolism
phosphatidylinositol synthase (Homo sapiens)_bkwd
keratan sulfate II (core 2-linked), degradation product 4
GENE_ASSOCIATION: (8854.2) or (501.1) or (216.1) or (224.1) or (8854.3) or (223.1) or (8854.1) SUBSYSTEM: Arginine and Proline Metabolism
N4-Acetylaminobutanal:NAD+ oxidoreductase
24 trihydroxy cholesterol transport_bkwd
Calcitroic acid transport from mitochondria
3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase_bkwd
protoporphyrinogen oxidase, mitochondrial
GENE_ASSOCIATION: (5498.1) SUBSYSTEM: Heme Biosynthesis
carboxylic acid dissociation, mitochondrial_bkwd
(phosphoethanolaminyl-mannosyl),(phosphoethanolaminyl)-dimannosyl-glucosaminyl-acylphosphatidylinositol (H7')
FORMULA: C53H100N3O35P3FULLRCO2FULLR2CO2
fatty acyl-CoA desaturase (n-C20:3CoA -> n-C20:4CoA)
GENE_ASSOCIATION: (3992.1) SUBSYSTEM: Fatty acid elongation
dimethylglycine transport via diffusion (cytosol to mitochondria)_bkwd
Diacylglycerol phosphate kinase (homo sapiens)_fwd
GENE_ASSOCIATION: (6513.1) or (6515.1) or (6514.1) SUBSYSTEM: Transport, Extracellular
methylenetetrahydrofolate dehydrogenase (NADP), mitochondrial_fwd
GENE_ASSOCIATION: (7357.1) SUBSYSTEM: Sphingolipid Metabolism
11-deoxycortisol intracellular transport_fwd
GENE_ASSOCIATION: SUBSYSTEM: Fatty Acid Metabolism
deoxyinosine transport via diffusion_fwd
GENE_ASSOCIATION: (5236.1) SUBSYSTEM: Pentose Phosphate Pathway
heparan sulfate transport, golgi to extracellular
GENE_ASSOCIATION: SUBSYSTEM: Tryptophan metabolism
1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)
alpha-methylacyl-CoA racemase (reductase)
GENE_ASSOCIATION: (23600.1) or (23600.2) SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (52.1) or (52.3) or (52.2) SUBSYSTEM: Riboflavin Metabolism
L-glutamine transport via electroneutral transporter
13-cis-4-oxo-retinoic acid transport, Nuclear_fwd
13-cis-4-oxo-retinoic acid isomerase_bkwd
thromboxane A2 intracellular transport_bkwd
citrate transport via sodium symport_bkwd
GENE_ASSOCIATION: (284111.1) SUBSYSTEM: Transport, Extracellular
keratan sulfate II biosynthesis, precursor 9
acetyl-CoA C-acetyltransferase, mitochondrial_fwd
GENE_ASSOCIATION: (38.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (8824.1) SUBSYSTEM: Alkaloid biosynthesis II
GENE_ASSOCIATION: (2194.1) SUBSYSTEM: Fatty acid elongation
4-(2-Aminophenyl)-2,4-dioxobutanoate dehydratase
L-carnitine transport out of mitochondria via diffusion
GENE_ASSOCIATION: (788.1) SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: (23600.2) or (23600.1) SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: SUBSYSTEM: Tetrahydrobiopterin
alanine-glyoxylate transaminase (irreversible), mitochondrial
GENE_ASSOCIATION: (64902.1) or (64850.1) SUBSYSTEM: Alanine and Aspartate Metabolism
dehydrodolichol phosphate phosphatase (uterus)
keratan sulfate II (core 2) transport, extracellular to lysosome
pyridoxamine transport via diffusion_fwd
GENE_ASSOCIATION: (6528.1) SUBSYSTEM: Transport, Extracellular
UDP-D-galactose:D-xylose galactosyltransferase, Golgi apparatus
GENE_ASSOCIATION: (11285.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
Cyanide transport via diffusion (mitochondrial)_bkwd
GENE_ASSOCIATION: (2583.1) SUBSYSTEM: Sphingolipid Metabolism
Beta-1,4 N-acetylgalactosaminyltransferase
GENE_ASSOCIATION: (1551.1) SUBSYSTEM: Steroid Metabolism
Fumarate:sulfate antiport, mitochondrial_fwd
chloride transport via hydroxide countertransport (2:1)
GENE_ASSOCIATION: (55454.1) or (55790.1) or (337876.1) or (79586.1) and (22856.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II, Golgi
cob(I)alamin adenosyltransferase, mitochondrial_bkwd
GENE_ASSOCIATION: (166785.1) SUBSYSTEM: Vitamin B12 Metabolism
acetoacetate intracellular transport unknown mechanism_fwd
Choline transport, nuclear through pores_fwd
3,4-Dihydroxyphenylethyleneglycol:NAD+ oxidoreductase_bkwd
GENE_ASSOCIATION: (3706.1) or (80271.1) or (3707.1) SUBSYSTEM: Inositol Phosphate Metabolism
Procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase
GENE_ASSOCIATION: (5352.2) or (5351.1) or (8985.1) or (5352.1) SUBSYSTEM: Lysine Metabolism
GENE_ASSOCIATION: (10965.1) or (10005.1) or (10005.3) or (10005.2) SUBSYSTEM: Fatty Acid Metabolism
chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 5
GENE_ASSOCIATION: (7296.4) or (7296.1) or (7296.3) or (7296.2) SUBSYSTEM: Miscellaneous
Thioredoxin (ubiquinone 10) reductase (NADH)
GENE_ASSOCIATION: (84693.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
methylmalonyl-CoA epimerase/racemase_bkwd
GENE_ASSOCIATION: SUBSYSTEM: Aminosugar Metabolism
glycophosphatidylinositol (GPI)-anchored protein precursor
pregnenolone intracellular transport_bkwd
3-hydroxyisobutyrate dehydrogenase, mitochondrial_bkwd
GENE_ASSOCIATION: (11112.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
deoyguanosine transport via diffusion_fwd
27 trihydroxy cholesterol transport_bkwd
DNA (cytosine-5-)-methyltransferase, nucleus
glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)
hydroxylated estrogen derivative transport_fwd
GENE_ASSOCIATION: (124583.1) SUBSYSTEM: Nucleotides
nucleoside-diphosphatase (IDP), extracellular
methenyltetrahydrifikate cyclohydrolase, mitochondrial_fwd
N-acetylgalactosamine 4-beta-galactosyltransferase, Golgi apparatus
potassium transport via proton antiport_bkwd
GENE_ASSOCIATION: (84679.1) or (23315.1) SUBSYSTEM: Transport, Golgi Apparatus
(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase (liver)
GENE_ASSOCIATION: (29880.1) SUBSYSTEM: N-Glycan Biosynthesis
nucleoside-diphosphate kinase (ATP:GDP), mitochondrial_bkwd
GENE_ASSOCIATION: (4907.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (26.1) or (314.1) or (314.2) SUBSYSTEM: Histidine Metabolism
sphingolipid long chain base kinase (sphinganine)
GENE_ASSOCIATION: (56848.1) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (3290.2) or (3290.1) SUBSYSTEM: Steroid Metabolism
11-beta-hydroxysteroid dehydrogenase type 1_fwd
N-acetylglucosamine-6-phosphate deacetylase
GENE_ASSOCIATION: (51005.1) SUBSYSTEM: Aminosugar Metabolism
11-beta-hydroxysteroid dehydrogenase type 1_bkwd
UDP-Xyl endoplasmic reticular transport via CMP antiport_fwd
5-Methylthio-5-deoxy-D-ribose 1-phosphate
2-dehydro-3-deoxy-phosphogluconate aldolase, mitochondrial_bkwd
Gamma-glutamyl hydrolase (5THF), extracellular
4-aminobutanoate mitochondrial transport via diffusion_bkwd
GENE_ASSOCIATION: (8802.1 and 8803.1) SUBSYSTEM: Citric Acid Cycle
Succinate--CoA ligase (ADP-forming)_bkwd
phosphatidylinositol-3-phosphate 3-phosphatase, nuclear
GENE_ASSOCIATION: (6535.1) or (6537.1) SUBSYSTEM: Transport, Extracellular
Creatine transport (sodium symport) (2:1)_bkwd
UDP-GlcNAc:N-acetyl-D-glucosaminyl diphosphodolichol N-acetyl-D-glucosaminyltransferase (liver)
GENE_ASSOCIATION: (1716.5) or (1716.1) or (1716.4) or (1716.2) or (1716.3) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (2643.1) SUBSYSTEM: Tetrahydrobiopterin
chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1
GENE_ASSOCIATION: (1152.1) or (1158.1) and (1152.1) or (1158.1) SUBSYSTEM: Urea cycle/amino group metabolism
CO2 endoplasmic reticular transport via diffusion_bkwd
3 alpha-hydroxysteroid dehydrogenase (type 3)_bkwd
GENE_ASSOCIATION: (1109.1) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (10558.1 and 9517.1) SUBSYSTEM: Sphingolipid Metabolism
Thiamine transport in via proton antiport_fwd
GENE_ASSOCIATION: (22978.1) SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (11254.1) or (54407.1) SUBSYSTEM: Transport, Extracellular
L-histidine transport in via sodium symport
chondroitin sulfate A transport, golgi to extracellular
bicarbonate transport (HCl/NaHCO3 exchange)_fwd
GENE_ASSOCIATION: (9498.1) or (57282.1) SUBSYSTEM: Transport, Extracellular
gluconolactonase, endoplasmic reticulum_fwd
GENE_ASSOCIATION: (1717.1) SUBSYSTEM: Cholesterol Metabolism
3,4-Dihydroxy-L-phenylalanine transport_bkwd
sodium proton antiporter (H:NA is 1:1)_fwd
S-adenosyl-L-methionine nuclear transport_bkwd
Iodide:hydrogen-peroxide oxidoreductase 4
GENE_ASSOCIATION: (6532.1) SUBSYSTEM: Transport, Extracellular
Seratonin reversible transport in via sodium symport/potassium antiport (1:2)_fwd
GENE_ASSOCIATION: (115584.1) SUBSYSTEM: Transport, Extracellular
inositol transport via sodium symport_fwd
GENE_ASSOCIATION: (5105.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: SUBSYSTEM: Keratan sulfate degradation
GENE_ASSOCIATION: (10682.1) SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (6675.1) or (91373.1) SUBSYSTEM: Aminosugar Metabolism
4-aminobutanoate mitochondrial transport via diffusion_fwd
GENE_ASSOCIATION: (223.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
PHEACGLN extracellular transport via diffusion_bkwd
trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)
glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)
GENE_ASSOCIATION: (6539.1) SUBSYSTEM: Transport, Extracellular
Betaine transport (sodium symport) (2:1)_fwd
s2l2n2m2masn transport, extracellular to lysosome
diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase
Prostaglandin-H2 D-isomerase [Precursor]_fwd
GENE_ASSOCIATION: (5730.1) or (27306.1) SUBSYSTEM: Eicosanoid Metabolism
Diphosphate transporter, endoplasmic reticulum_fwd
GENE_ASSOCIATION: (8972.1) SUBSYSTEM: Starch and Sucrose Metabolism
Lacto-N-fucopentaosyl III ceramide exchange
nucleoside-diphosphate kinase (ATP:dTDP), nuclear_bkwd
keratan sulfate I biosynthesis, precursor 16
L-alanine/L-glutamine Na-dependent exchange (Ala-L in)
adenine facilated transport from lysosome_bkwd
GENE_ASSOCIATION: (4200.1) or (10873.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (435.1) SUBSYSTEM: Alanine and Aspartate Metabolism
bicarbonate transport (HCl/NaHCO3 exchange)_bkwd
aldosterone intracellular transport_bkwd
(alpha-D-Glucosyl)-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
7-alpha,25-Dihydroxycholesterol exchange
Sarcosine transport (extracellular to cytosol)
GENE_ASSOCIATION: (3073.1 and 3074.1) or (3073.1) or (3074.1) SUBSYSTEM: Hyaluronan Metabolism
S-adenosyl-L-methionine nuclear transport_fwd
CO2 transport (diffusion), mitochondrial_fwd
Nicotinamide adenine dinucleotide exchange
nucleoside-diphosphate kinase (ATP:dGDP), nuclear_fwd
lysophosphatidylcholine (homo sapiens) exchange
GENE_ASSOCIATION: (22305.2) or (2182.1) or (2180.1) or (2181.2) or (2181.1) or (22305.1) SUBSYSTEM: Fatty acid activation
hydroxypyruvate decarboxylase, mitochondria
chondroitin sulfate E (GalNAc4,6diS-GlcA), free chain
Beta oxidation of long chain fatty acid (odd chain)
GENE_ASSOCIATION: (291.1) or (293.1) or (292.1) SUBSYSTEM: Transport, Mitochondrial
androsterone intracellular transport_fwd
GENE_ASSOCIATION: (6646.1) SUBSYSTEM: Cholesterol Metabolism
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
2,3-dioxo-L-gulonate decarboxylase (L-lyxonate-forming)
GENE_ASSOCIATION: (3038.2) or (3036.1) or (3038.1) or (3037.1) SUBSYSTEM: Hyaluronan Metabolism
GENE_ASSOCIATION: (9334.1) or (2683.1) or (8704.2) or (8704.1) or (8703.1) SUBSYSTEM: Keratan sulfate biosynthesis
GENE_ASSOCIATION: (30.1 and 51.2 and 1962.1) or (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1) or (3295.1 and 30.1 and 51.2) SUBSYSTEM: Fatty acid oxidation, peroxisome
GENE_ASSOCIATION: (5210.1) or (5207.1) or (5209.1) or (5208.1) SUBSYSTEM: Fructose and Mannose Metabolism
GENE_ASSOCIATION: (4594.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (2729.1) and (2730.1) SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (64781.1) or (64781.2) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (5240.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
GENE_ASSOCIATION: (29968.1) or (29968.2) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (134526.1) SUBSYSTEM: Pyruvate Metabolism
keratan sulfate I biosynthesis, precursor 7
GENE_ASSOCIATION: (1375.2) or (1375.3) or (1374.1) or (126129.1) or (1375.1) SUBSYSTEM: Carnitine shuttle
11-deoxycorticosterone intracellular transport_fwd
glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})
glycoprotein 6-alpha-L-fucosyltransferase
GENE_ASSOCIATION: (2530.4) or (2530.1) or (2530.3) or (2530.2) or (2530.5) SUBSYSTEM: N-Glycan Biosynthesis
S-Adenosyl-L-homocysteine intracellular diffusion_fwd
GENE_ASSOCIATION: (80055.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
glycophosphatidylinositol (GPI) deacylase, endoplasmic reticulum
GENE_ASSOCIATION: (6820.1) SUBSYSTEM: Steroid Metabolism
L-aminoadipate-semialdehyde dehydrogenase (NADH)
GENE_ASSOCIATION: (3628.1) SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (8534.1) or (9469.1) SUBSYSTEM: Keratan sulfate biosynthesis
GENE_ASSOCIATION: (6566.1) or (9194.1) SUBSYSTEM: D-alanine metabolism
pyruvate peroxisomal transport via proton symport_bkwd
(R)-3-Hydroxybutanoate transport via H+ symport_bkwd
5-methyltetrahydrofolate transport via anion exchange_bkwd
aspartate carbamoyltransferase (reversible)_fwd
GENE_ASSOCIATION: (223.1) SUBSYSTEM: beta-Alanine metabolism
GENE_ASSOCIATION: (2937.1) SUBSYSTEM: Glutathione Metabolism
(alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
3 alpha-hydroxysteroid dehydrogenase (type 3)_fwd
GENE_ASSOCIATION: (6342.1) SUBSYSTEM: Transport, Peroxisomal
Butyrate transport via proton symport, reversible_bkwd
GENE_ASSOCIATION: (10678.1) or (10678.2) SUBSYSTEM: Blood Group Biosynthesis
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
GENE_ASSOCIATION: (23382.1) or (191.1) or (10768.1) or (10768.2) SUBSYSTEM: Selenoamino acid metabolism
GENE_ASSOCIATION: (60482.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (471.1) SUBSYSTEM: IMP Biosynthesis
5-formyltetrahydrofolate transport via anion exchange_bkwd
GENE_ASSOCIATION: (191.1) or (10768.2) or (10768.1) SUBSYSTEM: Methionine Metabolism
2,6 dimethylheptanoyl carnitine transport_fwd
GENE_ASSOCIATION: (11309.1) or (6579.1) or (28234.1) or (10599.1) SUBSYSTEM: Transport, Extracellular
dehydroepiandrosterone sulfate transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: (28234.1) or (28231.1) or (10599.1) or (6579.1) or (53919.1) SUBSYSTEM: Transport, Extracellular
T3 transport via bicarbonate countertransport_fwd
Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) (cytosol)
GENE_ASSOCIATION: (7054.1) or (7054.3) or (7054.2) SUBSYSTEM: Tyrosine metabolism
dimannosyl-glucosaminyl-acylphosphatidylinositol (H3)
CO2 endoplasmic reticular transport via diffusion_fwd
GENE_ASSOCIATION: (2799.1) SUBSYSTEM: Heparan sulfate degradation
glucoamylase, extracellular (glygn5 -> malt)
L-proline reversible transport via proton symport (lysosome)_fwd
7-alpha,24(S)-Dihydroxycholesterol exchange
glycine passive transport to peroxisome_fwd
inorganic diphosphatase, endoplasmic reticulum
GENE_ASSOCIATION: (2538.1) or (92579.1) or (57818.1) SUBSYSTEM: Miscellaneous
alcohol dehydrogenase, forward rxn (ethanol -> acetaldehyde)
GENE_ASSOCIATION: (8802.1 and 8803.1) SUBSYSTEM: C5-Branched dibasic acid metabolism
Itaconate--CoA ligase (ADP-forming), mitochondrial_fwd
Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NADPH)
GENE_ASSOCIATION: (3291.1) SUBSYSTEM: Steroid Metabolism
11-beta-hydroxysteroid dehydrogenase type 2_fwd
purine-nucleoside phosphorylase (Xanthosine)_fwd
GENE_ASSOCIATION: (8540.1) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (6821.1) SUBSYSTEM: Cysteine Metabolism
GENE_ASSOCIATION: (115286.3) or (115286.2) or (115286.1) SUBSYSTEM: Transport, Mitochondrial
S-Adenosyl-L-methionine reversible transport, mitochondrial_fwd
GENE_ASSOCIATION: (56922.1 and 64087.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
methylcrotonoyl-CoA carboxylase, mitochondrial_fwd
de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b
GENE_ASSOCIATION: (55650.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
H2 mannosyltransferase, endoplasmic reticulum
keratan sulfate II biosynthesis, precursor 2
(alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
UDP-N-acetylgalactosamine diphosphorylase
GENE_ASSOCIATION: (57026.1) SUBSYSTEM: Vitamin B6 Metabolism
purine-nucleoside phosphorylase (Adenosine)_fwd
GENE_ASSOCIATION: (26289.2) or (26289.1) SUBSYSTEM: Nucleotides
docosa-4,7,10,13,16-pentaenoyl coenzyme A
GENE_ASSOCIATION: (3425.1) SUBSYSTEM: Heparan sulfate degradation
2,6 dimethylheptanoyl carnitine transport_bkwd
inositol-3,4,5,6-tetrakisphosphate 1-kinase
chondroitin sulfate C (GalNAc6S-GlcA), precursor 3
methylglutaconyl-CoA hydratase (reversible), mitochondrial_bkwd
acetate reversible transport via proton symport_fwd
chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 2
GENE_ASSOCIATION: (83733.1) or (8604.1) or (79751.1) or (10165.1) SUBSYSTEM: Transport, Mitochondrial
L-glutamate reversible transport via proton symport, mitochondrial_fwd
keratan sulfate I biosynthesis, precursor 8
GENE_ASSOCIATION: (875.1) SUBSYSTEM: Methionine Metabolism
GENE_ASSOCIATION: (7841.1) SUBSYSTEM: N-Glycan Biosynthesis
mannosyl-oligosaccharide glucosidase, endoplasmic reticulum
phosphatidylinositol-4,5-bisphosphate 4-phosphatase
beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human uterine homolog
GENE_ASSOCIATION: (873.1) SUBSYSTEM: Eicosanoid Metabolism
L-phenylalanine transport in via sodium symport
GENE_ASSOCIATION: (6520.1 and 8140.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (4837.1) SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (3425.1) SUBSYSTEM: Chondroitin sulfate degradation
glucosaminylphosphatidyl inositol acetyltransferase
GENE_ASSOCIATION: (284098.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
GENE_ASSOCIATION: (9514.1) SUBSYSTEM: Sphingolipid Metabolism
phosphoribosylaminoimidazolecarboxamide formyltransferase_bkwd
thiosulfate transport via sodium symport_fwd
Phosphatidylglycerol phosphate phosphatase (homo sapiens)
xylitol dehydrogenase (D-xyulose-forming)_bkwd
digalside hs intracellular transport_fwd
chloride transport via formate countertransport
GENE_ASSOCIATION: (5172.1) SUBSYSTEM: Transport, Extracellular
retinol dehydrogenase (11-cis,NADPH)_bkwd
GENE_ASSOCIATION: (10965.1) SUBSYSTEM: Fatty Acid Metabolism
L-proline reversible transport via proton symport_fwd
GENE_ASSOCIATION: SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
GENE_ASSOCIATION: (6574.1) or (6575.1) SUBSYSTEM: Transport, Extracellular
phosphate transport in/out via Na+ symporter_bkwd
3',5'-cyclic-nucleotide phosphodiesterase, Golgi
beta-ureidopropionase (D-3-amino-isobutanoate forming)
GENE_ASSOCIATION: (51733.1) SUBSYSTEM: Pyrimidine Catabolism
Glutathione dehydrogenase (dehydroascorbate reductase)
chloride transport via formate countertransport (2:1)
alpha-N-acetylglucosaminidase, lysosomal
GENE_ASSOCIATION: (4669.1) SUBSYSTEM: Heparan sulfate degradation
sulfate transport via bicarbonate countertransport
GENE_ASSOCIATION: (2806.1) SUBSYSTEM: Cysteine Metabolism
cysteine transaminase (mitochondrial)_fwd
nucleoside-diphosphate kinase (ATP:dIDP)_fwd
glycocholate transport via sodium cotransport
GENE_ASSOCIATION: (2235.1) or (2235.2) SUBSYSTEM: Heme Biosynthesis
protein-linked serine or threonine residue (O-glycosylation site)
GENE_ASSOCIATION: (30833.1) SUBSYSTEM: Pyrimidine Catabolism
GENE_ASSOCIATION: (1890.1) SUBSYSTEM: Pyrimidine Catabolism
GENE_ASSOCIATION: (8706.4) or (8706.1) or (8706.3) or (8706.2) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (5019.1) or (64064.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
intracellular transport (peroxisome)_bkwd
Retinol transport via faciliated diffusion
3,4-Dihydroxyphenylethyleneglycol transport (diffusion)_fwd
D-Lactaldehyde:NAD+ oxidoreductase (glutathione-formylating)_bkwd
nucleoside-diphosphatase (UDP), Golgi apparatus
GENE_ASSOCIATION: (9583.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (56474.1) or (56474.2) SUBSYSTEM: Pyrimidine Biosynthesis
GENE_ASSOCIATION: (8694.1) or (84649.1) SUBSYSTEM: Triacylglycerol Synthesis
acyl-CoA dehydrogenase (butanoyl-CoA), mitochondrial
keratan sulfate I biosynthesis, precursor 31
taurocholate transport via sodium cotransport
GENE_ASSOCIATION: (6529.1) or (6538.1) or (6540.1) or (6539.1) SUBSYSTEM: Transport, Extracellular
4-aminobutyrate reversible transport in via sodium symport (1:2)_fwd
Gamma-glutamyl hydrolase (6DHF), lysosomal
selenate transport via sodium symport_fwd
1D-myo-Inositol 1,3,4,5-tetrakisphosphate
phosphatidylinositol 4-phosphate phospholipase C
protein-linked serine residue (glycosaminoglycan attachment site)
GENE_ASSOCIATION: (3931.1) SUBSYSTEM: Fatty Acid Metabolism
N-acetylgalactosamine-6-sulfatase, lysosomal_fwd
GENE_ASSOCIATION: (3795.1) or (3795.2) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
GENE_ASSOCIATION: (6566.1) or (9123.1) or (9194.1) SUBSYSTEM: Transport, Extracellular
acetone transport via proton symport_fwd
fucosyl galactosylgloboside (homo sapiens)
GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) or (5476.1) and (2720.1) SUBSYSTEM: Galactose metabolism
GENE_ASSOCIATION: (6559.1) SUBSYSTEM: Transport, Extracellular
omega hydroxy testosterone transport_bkwd
GENE_ASSOCIATION: (549.1) or (3030.1) and (3032.1) or (1892.1) SUBSYSTEM: Tryptophan metabolism
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA) (mitochondria)_fwd
GENE_ASSOCIATION: (4200.1) SUBSYSTEM: Pyruvate Metabolism
uridine facilated transport in cytosol_fwd
FOR transporter, endoplasmic reticulum_fwd
alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
sphinganine intracellular transport_bkwd
GENE_ASSOCIATION: SUBSYSTEM: Cholesterol Metabolism
cytidylate kinase (dCMP,dCTP),nuclear_bkwd
Nicotinamide adenine dinucleotide phosphate
hydroxyacylglutathione hydrolase, mitochondrial
GENE_ASSOCIATION: (3029.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (6579.1) or (28234.1) or (10599.1) SUBSYSTEM: Transport, Extracellular
glycocholate transport via bicarbonate countertransport_fwd
1,4-alpha-glucan branching enzyme (glygn1 -> glygn2)
GENE_ASSOCIATION: (2632.1) SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (1633.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: SUBSYSTEM: Thiamine Metabolism
GENE_ASSOCIATION: (4598.1) SUBSYSTEM: Cholesterol Metabolism
L-erythro-4-Hydroxyglutamate:2-oxoglutarate aminotransferase, mitochondrial
GENE_ASSOCIATION: (2806.1) SUBSYSTEM: Arginine and Proline Metabolism
Dolichyl beta-D-glucosyl phosphate flippase (uterus)
dehydrodolichol phosphate phosphatase (liver)
hydrogen peroxide transport via diffusion_bkwd
keratan sulfate I, degradation product 1
3MLDA extracellular transport via diffusion_bkwd
inositol-1,3,4,5-trisphosphate 5-phosphatase
carbamoyl phosphate transport, endoplasmic reticulum_fwd
gq1balpha hs intracellular transport_fwd
Malate:thiosulfate antiport, mitochondrial_fwd
GENE_ASSOCIATION: (5096.1 and 5095.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
Propionyl-CoA carboxylase, mitochondrial
UDPglucose--hexose-1-phosphate uridylyltransferase_fwd
5-beta-cytochrome P450, family 27, subfamily A, polypeptide 1
GENE_ASSOCIATION: (1593.1) SUBSYSTEM: Bile Acid Biosynthesis
(alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (m)_bkwd
GENE_ASSOCIATION: (3030.1) and (3032.1) or (549.1) SUBSYSTEM: Limonene and pinene degradation
GENE_ASSOCIATION: (26062.1) SUBSYSTEM: Fatty Acid Metabolism
GDPFuc Golgi transport via CMP antiport_fwd
GENE_ASSOCIATION: (1036.1) SUBSYSTEM: Taurine and hypotaurine metabolism
GENE_ASSOCIATION: (1384.1) SUBSYSTEM: Fatty Acid Metabolism
carnitine O-aceyltransferase, mitochondrial_fwd
Pyridoxamine 5'-phosphate transport via diffusion, mitochondrial_bkwd
GENE_ASSOCIATION: (4597.1) SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (6470.1) or (6470.2) SUBSYSTEM: Lysine Metabolism
chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1
keratan sulfate I, degradation product 8
keratan sulfate I biosynthesis, precursor 29
GENE_ASSOCIATION: (2582.1) or (2582.2) SUBSYSTEM: Galactose metabolism
GENE_ASSOCIATION: (2203.1) or (5210.1) or (5207.1) or (5209.1) or (5208.1) or (8789.1) SUBSYSTEM: Fructose and Mannose Metabolism
chondroitin sulfate B (IdoA2S-GalNAc4s), precursor 5
phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})
GENE_ASSOCIATION: SUBSYSTEM: CoA Catabolism
5 alpha dihydrotesterone intracellular transport_bkwd
GENE_ASSOCIATION: (10610.1) SUBSYSTEM: Sphingolipid Metabolism
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
de-Fuc form of PA6 (w/o peptide linkage)
deoxyuridine transport via diffusion_bkwd
GENE_ASSOCIATION: (10993.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)
GENE_ASSOCIATION: (36.1) or (34.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
acyl-CoA dehydrogenase (2-methylbutanoyl-CoA), mitochondrial
GENE_ASSOCIATION: (2878.1) or (257202.1) SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (1806.1) SUBSYSTEM: Pyrimidine Catabolism
Pyridoxal 5'-phosphate transport via diffusion, mitochondrial_fwd
GENE_ASSOCIATION: (9194.1) or (23539.1) or (6566.1) or (9123.1) SUBSYSTEM: Transport, Extracellular
L-lactate reversible transport via proton symport_fwd
Benzene transporter, endoplasmic reticulum_fwd
GENE_ASSOCIATION: (10257.1) SUBSYSTEM: Transport, Extracellular
17-beta-D-glucuronide transport (ATP-dependent)
Etiocholan-3alpha-ol-17-one 3-glucuronide
Ubiquinone biosynthesis monooxgenase COQ6
GENE_ASSOCIATION: (51004.1) or (51004.2) SUBSYSTEM: Ubiquinone Biosynthesis
acetone mitochondrial transport via proton symport_fwd
GENE_ASSOCIATION: (8790.1) SUBSYSTEM: Fructose and Mannose Metabolism
fucose-1-phosphate guanylyltransferase_bkwd
1D-myo-Inositol 1,4,5,6-tetrakisphosphate
pyruvate reversible transport via proton symport_bkwd
GENE_ASSOCIATION: (4860.1) SUBSYSTEM: NAD Metabolism
acgagbside hs intracellular transport_bkwd
3-Methylimidazole acetaldehyde:NAD+ oxidoreductase
GENE_ASSOCIATION: (218.1) or (221.1) or (4129.1) or (222.1) or (220.1) SUBSYSTEM: Histidine Metabolism
GENE_ASSOCIATION: (2519.1) SUBSYSTEM: Keratan sulfate degradation
chondroitin sulfate A (GalNAc4S-GlcA), free chain
glutamate-5-semialdehyde dehydrogenase (m)
GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) or (5476.1) and (2720.1) SUBSYSTEM: N-Glycan Degradation
n2m2nmasn transport, extracellular to lysosome
GENE_ASSOCIATION: (93034.1) or (30833.1) or (93034.2) SUBSYSTEM: Pyrimidine Catabolism
nicotinate-nucleotide adenylyltransferase_bkwd
GENE_ASSOCIATION: (349565.1) or (23057.2) or (23057.1) SUBSYSTEM: NAD Metabolism
chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 5
inosine transport in via sodium (1:2) symport
GENE_ASSOCIATION: (6240.1 and 6241.1) SUBSYSTEM: Nucleotides
ribonucleoside-diphosphate reductase (UDP)
GENE_ASSOCIATION: (6541.1) or (6542.1) or (55089.1) or (84889.1) SUBSYSTEM: Transport, Extracellular
L-lysine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (10797.1) SUBSYSTEM: Folate Metabolism
methylenetetrahydrofolate dehydrogenase (NAD), mitochondrial_fwd
GENE_ASSOCIATION: (8398.1) or (5320.1) or (8398.2) SUBSYSTEM: Glycerophospholipid Metabolism
Dopamine reversible transport in via sodium symport (1:2)_fwd
nucleoside-diphosphate kinase (ATP:CDP),nuclear_bkwd
((N-acetyl-D-glucosaminyl)2-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)
13-cis-4-oxo-retinoic acid transport, Nuclear_bkwd
Gal-Gal-Gal-Gal-Gal-Glc-Cer (homo sapiens) exchange
sodium transport via diffusion (perioxisome)_fwd
D-proline reversible transport via proton symport_fwd
GENE_ASSOCIATION: (9060.1) or (9061.1) SUBSYSTEM: Nucleotides
carnitine transport peroxisome to mitochondria_fwd
Butyrate mitochondrial transport via proton symport, reversible_bkwd
N-acetylgalactosamine 3-beta-galactosyltransferase, Golgi apparatus
GENE_ASSOCIATION: (56913.1) SUBSYSTEM: O-Glycan Biosynthesis
GENE_ASSOCIATION: (622.2) or (622.3) or (622.1) SUBSYSTEM: Butanoate Metabolism
(R)-3-Hydroxybutanoate:NAD+ oxidoreductase_fwd
chondroitin sulfate C (GalNAc6S-GlcA) proteoglycan exchange
nucleoside-diphosphatase (UDP), extracellular
GENE_ASSOCIATION: (2944.1) or (2944.2) SUBSYSTEM: Vitamin A Metabolism
Gamma-glutamyl hydrolase (10FTHF7GLU), lysosomal
GENE_ASSOCIATION: (10195.4) or (10195.1) or (10195.3) or (10195.2) SUBSYSTEM: N-Glycan Biosynthesis
GENE_ASSOCIATION: (6898.1) or (2806.1) SUBSYSTEM: Tyrosine metabolism
tyrosine transaminase, mitochondrial_fwd
GENE_ASSOCIATION: (30833.1) SUBSYSTEM: Nucleotides
Choline transport, nuclear through pores_bkwd
purine-nucleoside phosphorylase (Guanosine)_bkwd
24,25-Dihydroxyvitamin D2 transport from cytoplasm
L-alanine/glycine reversible exchange_fwd
keratan sulfate II boisynthesis, precursor 2
GENE_ASSOCIATION: (9197.1) SUBSYSTEM: Transport, Endoplasmic Reticular
s2l2fn2m2masn transport, extracellular to lysosome
1-alkyl 2-lysoglycerol 3-phosphocholine exchange
(Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1
GENE_ASSOCIATION: (2542.1) SUBSYSTEM: Transport, Endoplasmic Reticular
glucose 6-phosphate endoplasmic reticular transport via diffusion_bkwd
nucleoside-diphosphate kinase (ATP:dGDP), mitochondrial_fwd
L-lactate reversible transport via sodium symport_fwd
glutathione peroxidase, mitochondria_fwd
GENE_ASSOCIATION: (10935.1) or (10935.2) or (2879.1) SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (53905.1) or (50506.1) or (53905.2) SUBSYSTEM: Tyrosine metabolism
Hydrogen peroxide synthesis (NADPH dependent)
sialyl (2,3) sialyl (2,6) galactosylgloboside (homo sapiens) exchange
3-amino-isobutyrate transport, mitochondrial
sphingosylphosphorylcholine (homo sapiens) exchange
GENE_ASSOCIATION: (27159.2) SUBSYSTEM: Aminosugar Metabolism
GENE_ASSOCIATION: (9023.1) SUBSYSTEM: Bile Acid Biosynthesis
galactose-6-sulfate sulfatase, lysosomal_bkwd
glycocholate transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: (6818.1) or (6818.3) or (6818.2) SUBSYSTEM: Tyrosine metabolism
sphingosylphosphorylcholine (homo sapiens)
GENE_ASSOCIATION: (9563.1) SUBSYSTEM: Pentose Phosphate Pathway
glucose 6-phosphate dehydrogenase, endoplasmic reticulum_bkwd
hydrogen peroxide transport via diffusion_fwd
GENE_ASSOCIATION: (952.1) SUBSYSTEM: Transport, Extracellular
M4C phosphoethanolaminyl transferase, endoplasmic reticulum
GENE_ASSOCIATION: (84720.2) and (5281.2) or (5281.1) and (84720.1) or (84720.1) and (5281.2) or (84720.2) and (5281.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
GENE_ASSOCIATION: (952.1) SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (22978.1) or (93034.2) or (93034.1) SUBSYSTEM: Purine Catabolism
L-threonine/L-glutamine Na-dependent exchange (Gln-L in)
chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 6
digalside hs intracellular transport_bkwd
GENE_ASSOCIATION: (11164.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (81537.1) SUBSYSTEM: Sphingolipid Metabolism
sphingoid base-phosphate phosphatase (sphinganine 1-phosphatase), endoplasmic reticulum
Gamma-glutamyl hydrolase (10FTHF5GLU), lysosomal
keratan sulfate I, degradation product 23
alkyl glycerol phosphocholine acetyl transferase
oxalate transport via bicarbonate countertransport
GENE_ASSOCIATION: (1836.1) or (10861.1) or (10861.3) or (10861.2) or (1811.1) SUBSYSTEM: Transport, Extracellular
L-serine/L-glutamine Na-dependent exchange (Gln-L in)
GENE_ASSOCIATION: (1585.1) SUBSYSTEM: Steroid Metabolism
hydroxysteroid (17-beta) dehydrogenase 4
GENE_ASSOCIATION: (3295.1) SUBSYSTEM: Bile Acid Biosynthesis
Iodide:hydrogen-peroxide oxidoreductase 2
GENE_ASSOCIATION: (23236.1) or (23236.2) SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol 4,5-bisphosphate phospholipase C, nucleus
cholesterol precursor intracellular transport_bkwd
GENE_ASSOCIATION: (1635.1) SUBSYSTEM: Pyrimidine Catabolism
L-glutamine/L-asparagine Na-dependent exchange (Gln-L in)
GENE_ASSOCIATION: (1312.1) or (1312.2) SUBSYSTEM: Tyrosine metabolism
pregnenolone intracellular transport_fwd
Phosphatidylserine synthase homo sapiens_bkwd
GENE_ASSOCIATION: (81490.1) SUBSYSTEM: Glycerophospholipid Metabolism
keratan sulfate I biosynthesis, precursor 1
bilirubin beta-diglucuronide transport MDR
alpha-amylase, extracellular (strch1 -> strch2)
hydrogen peroxide peroxisomal transport via diffusion_bkwd
S-adenosyl-L-homocysteine nuclear transport_bkwd
alkyl acylglycerol phosphoethanolamine transferase
fatty acyl-CoA desaturase (n-C24:5CoA -> n-C24:6CoA)
GENE_ASSOCIATION: (32.1) SUBSYSTEM: Fatty Acid Metabolism
alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
GENE_ASSOCIATION: (4248.1) SUBSYSTEM: N-Glycan Biosynthesis
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
GENE_ASSOCIATION: (50.1) SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (3073.1 and 3074.1) or (3074.1) or (3073.1) SUBSYSTEM: Chondroitin sulfate degradation
GENE_ASSOCIATION: (2203.1) or (8789.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (7372.1) SUBSYSTEM: Pyrimidine Biosynthesis
Butyrate transport via proton symport, reversible_fwd
GENE_ASSOCIATION: (53343.1) or (53343.3) or (53343.2) SUBSYSTEM: Nucleotides
(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)
GENE_ASSOCIATION: (171425.1) or (171425.2) SUBSYSTEM: Citric Acid Cycle
trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (x)_bkwd
phosphatidylinositol nuclear transport (diffusion)_bkwd
leukotriene C4 transport via bicarbonate countertransport_fwd
cytidylate kinase (dCMP,CTP),nuclear_fwd
GENE_ASSOCIATION: (23761.1) SUBSYSTEM: Glycerophospholipid Metabolism
fatty acyl-CoA desaturase (n-C22:4CoA -> n-C22:5CoA)
GENE_ASSOCIATION: SUBSYSTEM: Fatty acid elongation
GENE_ASSOCIATION: (35.1) or (35.1) or (34.1) or (34.1) SUBSYSTEM: Fatty acid oxidation
GENE_ASSOCIATION: (4121.1) or (57134.1) or (10905.1) SUBSYSTEM: N-Glycan Biosynthesis
chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), free chain
methylenetetrahydrofolate dehydrogenase (NAD), mitochondrial_bkwd
chondroitin sulfate C (GalNAc6S-GlcA), free chain
mesaconate--CoA ligase (GDP-forming)_bkwd
pyridoxamine transport via diffusion_bkwd
GENE_ASSOCIATION: (3417.1) SUBSYSTEM: Citric Acid Cycle
D-alanine/glycine reversible exchange_bkwd
25-hydroxyvitamin D2 transport in cytoplasm
L-glutamate secretion via secretory vesicle (ATP driven)
GENE_ASSOCIATION: (57084.1) or (246213.1) or (57030.1) SUBSYSTEM: Transport, Extracellular
aspartate-glutamate mitochondrial shuttle
GENE_ASSOCIATION: (8604.1) or (10165.1) SUBSYSTEM: Transport, Mitochondrial
5-hydroxy-L-tryptophan secretion via secretory vesicle (ATP driven)
keratan sulfate I, degradation product 1 exchange
palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA)
GENE_ASSOCIATION: (6319.1) SUBSYSTEM: Fatty acid elongation
2-dehydro-3-deoxy-phosphogluconate aldolase, mitochondrial_fwd
GENE_ASSOCIATION: (6541.1) or (84889.1) or (6542.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (9154.2) or (9154.1) or (64078.1) or (9153.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2548.1) SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (80146.1) SUBSYSTEM: Nucleotide Sugar Metabolism
UDP-D-glucuronate decarboxylase, Golgi apparatus
GENE_ASSOCIATION: (6579.1) or (10599.1) SUBSYSTEM: Transport, Extracellular
cholate transport via bicarbonate countertransport_fwd
nucleoside-diphosphate kinase (ATP:GDP)_bkwd
GENE_ASSOCIATION: (3028.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
3-hydroxyacyl-CoA dehydrogenase (2-Methylacetoacetyl-CoA), mitochondrial_fwd
leukotriene C4 transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: (1841.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (226.2) or (229.1) or (226.3) or (230.1) or (226.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase_fwd
taurocholate transport via bicarbonate countertransport_fwd
3-mercaptolactate-cysteine disulfide transport, extracellular
D-alanine transport via proton symport_fwd
keratan sulfate I biosynthesis, precursor 6
GENE_ASSOCIATION: (113451.1) SUBSYSTEM: Arginine and Proline Metabolism
GENE_ASSOCIATION: (2023.1) or (26237.1) or (2027.2) or (2027.1) or (2026.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
nucleoside-diphosphate kinase (ATP:CDP),nuclear_fwd
AMP/ATP transporter, endoplasmic reticulum_fwd
galactocerebroside intracellular transport_fwd
N-Acetyl-D-glucosaminyldiphosphodolichol, human liver homolog
(alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
GENE_ASSOCIATION: (10841.1) or (10841.2) SUBSYSTEM: Histidine Metabolism
GENE_ASSOCIATION: (9056.1 and 6519.1) SUBSYSTEM: Transport, Extracellular
Serine/Lysine Na-dependent exchange (Ser in)
s2l2fn2m2masn transport, Golgi to extracellular
(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
carboxylic acid dissociation, mitochondrial_fwd
acetaldehyde mitochondrial diffusion_bkwd
GENE_ASSOCIATION: (7084.1) or (7083.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (4522.1) or (285216.1) or (80068.1) SUBSYSTEM: Folate Metabolism
methenyltetrahydrofolate cyclohydrolase_fwd
formaldehyde transport via diffusion (mitochondrial)_fwd
GENE_ASSOCIATION: (54363.1) or (51179.2) or (51179.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial_fwd
GENE_ASSOCIATION: (3939.1) SUBSYSTEM: Pyruvate Metabolism
glycine reversible transport via proton symport_bkwd
T4 transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: (6576.1) SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: (6476.1) SUBSYSTEM: Starch and Sucrose Metabolism
oligo-1,6-glucosidase (strch2 ->strch3), extracellular
acetoacetate transport via proton symport_bkwd
GENE_ASSOCIATION: (6566.1) or (9194.1) SUBSYSTEM: Transport, Extracellular
chondroitin sulfate C (GalNAc6S-GlcA), degradation product 2
S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
GENE_ASSOCIATION: (3176.1) SUBSYSTEM: Histidine Metabolism
omega hydroxy hexadecanoate (n-C16:0) exchange
fatty acyl-CoA desaturase (n-C20:4CoA -> n-C20:5CoA)
glucose transport, endoplasmic reticulum_bkwd
nucleoside-diphosphate kinase (ATP:dCDP), mitochondrial_bkwd
gulonate dehydrogenase, endoplasmic reticulum_bkwd
GENE_ASSOCIATION: (443.1) or (91703.1) SUBSYSTEM: Alanine and Aspartate Metabolism
4-aminobutyrate reversible transport in via sodium symport (1:2)_bkwd
g2m8masn transport from endoplasmic reticulum to Golgi apparatus
GENE_ASSOCIATION: (3658.1) or (48.1) SUBSYSTEM: Citric Acid Cycle
cytidine facilated transport in cytosol_fwd
3-Aminopropanoate:2-oxoglutarate aminotransferase (m)_fwd
acetone transport via proton symport_bkwd
Ubiquinone biosynthesis methyltransferase COQ5
10-Formyltetrahydrofolate lysosomal transport via diffusion_bkwd
fatty-acid--CoA ligase (hexadecenoate)_bkwd
5-Methylthio-5-deoxy-D-ribulose 1-phosphate
2,3-diketo-5-methylthio-1-phosphopentane degradation reaction
Squalene epoxidase, endoplasmic reticular (NADP)
GENE_ASSOCIATION: (6713.1) SUBSYSTEM: Cholesterol Metabolism
2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate), mitochondrial
GENE_ASSOCIATION: (23417.1) SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (27235.1) SUBSYSTEM: Ubiquinone Biosynthesis
heparan sulfate 6-sulfotransferase, Golgi apparatus
GENE_ASSOCIATION: (266722.1) or (9394.1) or (90161.2) or (90161.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
cytidine transport in via sodium symport
GENE_ASSOCIATION: (9154.1) or (9154.2) or (64078.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2990.1) SUBSYSTEM: Hyaluronan Metabolism
GENE_ASSOCIATION: (4329.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
methylmalonate-semialdehyde dehydrogenase
galactose transport via sodium symport_bkwd
transport into the cytosol from peroxisome (carnitine)
1D-myo-Inositol 3,4,5,6-tetrakisphosphate
GENE_ASSOCIATION: (3073.1 and 3074.1) or (3073.1) or (3074.1) SUBSYSTEM: Chondroitin sulfate degradation
phosphoribosylpyrophosphate synthetase_bkwd
taurine transport (sodium symport) (cytosol to peroxisome)_fwd
GENE_ASSOCIATION: (6533.1) SUBSYSTEM: Taurine and hypotaurine metabolism
cytidylate kinase (dCMP,GTP),nuclear_fwd
GENE_ASSOCIATION: (55512.1) or (55512.2) SUBSYSTEM: Sphingolipid Metabolism
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
GENE_ASSOCIATION: (9951.1) or (9952.1) or (9955.1) or (9953.1) or (9954.1) or (64711.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
L-valine transport via diffusion (extracellular to cytosol)_bkwd
phosphatidylethanolamine scramblase_bkwd
GENE_ASSOCIATION: (55790.1) or (55454.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
UDPGal-chondroitin acetylgalactosaminyltransferase I, Golgi
5-diphosphoinositol-1,2,3,4,6-pentakisphosphate diphosphohydrolase, nuclear
GENE_ASSOCIATION: (248.1) or (251.1) or (249.1) or (250.1) SUBSYSTEM: Glycerophospholipid Metabolism
nicotinate-nucleotide diphosphorylase (carboxylating)
GENE_ASSOCIATION: (23475.1) SUBSYSTEM: NAD Metabolism
hypoxanthine facilated transport from lysosome_fwd
(alpha-D-mannosyl)3-beta-D-mannosyl-diacetylchitodiphosphodolichol, human liver homolog
carnitine dimethyl nonanoyl transferase, revsible, peroxisomal_bkwd
GENE_ASSOCIATION: (54677.1) or (1384.2) SUBSYSTEM: Fatty Acid Metabolism
1D-myo-Inositol 1,3,4,6-tetrakisphosphate
GENE_ASSOCIATION: (1557.1) SUBSYSTEM: CYP Metabolism
galactose-1-phosphate uridylyltransferase_fwd
acetyl-CoA C-acetyltransferase (dodecanoyl), peroxisomal
GENE_ASSOCIATION: (7296.1) or (7296.4) or (7296.2) or (7296.3) SUBSYSTEM: Miscellaneous
Thioredoxin (ubiquinone 10) reductase (NADPH)
GENE_ASSOCIATION: (23530.2) or (23530.1) SUBSYSTEM: NAD Metabolism
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
GENE_ASSOCIATION: (1109.1) SUBSYSTEM: Bile Acid Biosynthesis
L-4-hydroxyglutamate semialdehyde dehydrogenase, mitochondrial_bkwd
GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Arginine and Proline Metabolism
bicarbonate transport (Na/HCO3 1:2 cotransport)_bkwd
methylenetetrahydrofolate dehydrogenase (NADP)_bkwd
GENE_ASSOCIATION: (4522.1) SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (64802.1) SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (2990.1) SUBSYSTEM: Chondroitin sulfate degradation
stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)
inositol-1,4,5-trisphosphate 5-phosphatase
arachidonic acid transport into the mitochondria
phosphogluconate dehydrogenase, endoplasmic reticulum
GENE_ASSOCIATION: SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (2618.1) or (2618.2) SUBSYSTEM: IMP Biosynthesis
GENE_ASSOCIATION: (51540.1) SUBSYSTEM: Selenoamino acid metabolism
(alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
adenosine transport (Na/Adn cotransport)
GENE_ASSOCIATION: (126792.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
UDP-D-galactose:galactosylxylose galactosyltransferase, Golgi apparatus
chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S) proteoglycan
GENE_ASSOCIATION: (9187.1) or (25769.1) SUBSYSTEM: Transport, Extracellular
omega hydroxy testosterone transport_fwd
phosphatidyl glycerol phosphate (homo sapiens)
aldehyde dehydrogenase (acetaldehyde, NADP)
GENE_ASSOCIATION: (223.1) or (221.1) or (218.1) or (8854.1) or (8854.3) or (222.1) or (8854.2) or (224.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (55586.1) SUBSYSTEM: Inositol Phosphate Metabolism
2,3,4,5-Tetrahydropyridine-2-carboxylate transport, peroxisomal_fwd
Tyramine O-sulfate transport (diffusion)
keratan sulfate I, degradation product 38
phosphoribosylaminoimidazolesuccinocarboxamide synthase_bkwd
GENE_ASSOCIATION: (9453.1) SUBSYSTEM: Cholesterol Metabolism
chloride transport via bicarbonate countertransport
GENE_ASSOCIATION: (5471.1) SUBSYSTEM: IMP Biosynthesis
glutamine phosphoribosyldiphosphate amidotransferase
GENE_ASSOCIATION: SUBSYSTEM: D-alanine metabolism
GENE_ASSOCIATION: (645.1) or (644.1) SUBSYSTEM: Heme Degradation
GENE_ASSOCIATION: (5338.1) SUBSYSTEM: Glycerophospholipid Metabolism
phosphate transport in/out via two Na+ symporter_fwd
GENE_ASSOCIATION: (142680.1) SUBSYSTEM: Transport, Extracellular
biotin-[acetyl-CoA-carboxylase] ligase, mitochondrial
3-Decaprenyl-4-hydroxy-5-methoxybenzoate decarboxylation
GENE_ASSOCIATION: (6484.1) or (6482.1) or (6483.1) or (6482.2) SUBSYSTEM: Keratan sulfate biosynthesis
Dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase (uterus)
GENE_ASSOCIATION: (6185.1 and 1650.1 and 6184.1 and 1603.1) SUBSYSTEM: N-Glycan Biosynthesis
Dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase (uterus)
inositol hexakisphosphate nuclear transport (diffusion)_fwd
guanosine facilated transport from lysosome_fwd
GENE_ASSOCIATION: (81539.1) or (11254.1) or (54407.1) or (55089.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (8574.1) or (231.1) or (10327.2) or (10327.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (7086.1) or (84076.1) or (8277.1) SUBSYSTEM: Pentose Phosphate Pathway
guanosine facilated transport in cytosol_bkwd
GENE_ASSOCIATION: (2806.1) SUBSYSTEM: Alanine and Aspartate Metabolism
FORMULA: C55H106N4O38P4FULLRCO2FULLR2CO2X
glycophosphatidylinositol (GPI)-anchored protein
pantetheine-phosphate adenylyltransferase_bkwd
purine-nucleoside phosphorylase (Deoxyinosine)_bkwd
GENE_ASSOCIATION: (2744.1) or (27165.2) or (27165.1) SUBSYSTEM: Glutamate metabolism
keratan sulfate I, degradation product 40
1-alpha,24R,25-Vitamin D-hydroxylase (D2)
heparan sulfate proteoglycan protease, lysosome (endosome)
Xyl-L-Ser (protein) transport from endoplasmic reticulum to Golgi apparatus
keratan sulfate I, degradation product 37
GENE_ASSOCIATION: (2805.1) SUBSYSTEM: Cysteine Metabolism
3-sulfino-alanine transaminase (irreversible)
D-fructose transport via sodium cotransport_bkwd
(R)-3-Hydroxybutanoate mitochondrial transport via H+ symport_fwd
Seratonin reversible transport in via sodium symport/potassium antiport (1:2)_bkwd
3,4-Dihydroxyphenylethyleneglycol:NAD+ oxidoreductase_fwd
GENE_ASSOCIATION: (81539.1) or (11254.1) or (54407.1) or (6584.1) SUBSYSTEM: Transport, Extracellular
L-methionine transport in via sodium symport
Malate:sulfate antiport, mitochondrial_bkwd
5-methylthioribose-1-phosphate isomerase_bkwd
GENE_ASSOCIATION: (4126.1) SUBSYSTEM: N-Glycan Degradation
glycine hydroxymethyltransferase, reversible, mitochondrial_fwd
GENE_ASSOCIATION: (6472.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
aspartate carbamoyltransferase (reversible)_bkwd
GENE_ASSOCIATION: (23743.1) or (635.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
betaine-homocysteine S-methyltransferase
glutamate dehydrogenase (NAD) (mitochondrial)_fwd
phosphoribosylglycinamide formyltransferase_fwd
2-keto-3-deoxy-D-glycero-D-galactononic acid
phosphatidylinositol-4-phosphate 4-phosphatase, nuclear
S-Adenosyl-L-methionine reversible transport, mitochondrial_bkwd
deoxyribose transport via diffusion_bkwd
GENE_ASSOCIATION: (2581.1) SUBSYSTEM: Sphingolipid Metabolism
purine-nucleoside phosphorylase (Inosine)_fwd
nucleoside-diphosphate kinase (ATP:dCDP), nuclear_bkwd
keratan sulfate I transport, extracellular to lysosome
GENE_ASSOCIATION: (175.1) SUBSYSTEM: N-Glycan Degradation
H6' phosphoethanolaminyl transferase, endoplasmic reticulum
GENE_ASSOCIATION: (5281.1) and (54872.1) or (5281.2) and (54872.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
inositol-1,3,4-trisphosphate 4-phosphatase
GENE_ASSOCIATION: (10991.1) SUBSYSTEM: Transport, Extracellular
primed glycogenin (glycogenin-8[1,4-Glc])
arginine mitochondrial transport via ornithine carrier_fwd
glycine passive transport to mitochondria_bkwd
Glutamine transport (Na, H coupled)_bkwd
GDPmannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase (uterus)
glucose transport via sodium symport_fwd
sgalside hs intracellular transport_bkwd
2-Methylprop-2-enoyl-CoA (2-Methylbut-2-enoyl-CoA), mitochondrial_fwd
GENE_ASSOCIATION: (1892.1) or (3030.1) and (3032.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
Lecithin retinol acyltransferase (11-cis)
acetoacetate transport via proton symport_fwd
GENE_ASSOCIATION: (158.1) or (158.2) SUBSYSTEM: IMP Biosynthesis
Dolichyl-phosphate D-mannosyltransferase (uterus)
GENE_ASSOCIATION: (8942.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (8612.1) or (8611.1) or (8613.1) or (8611.2) SUBSYSTEM: Triacylglycerol Synthesis
Malonyl-CoA-ACP transacylase, mitochondrial_fwd
GENE_ASSOCIATION: (27349.2) or (27349.1) SUBSYSTEM: Fatty Acid Metabolism
bicarbonate transport (Na/HCO3 cotransport)_fwd
GENE_ASSOCIATION: (9497.1) SUBSYSTEM: Transport, Extracellular
Histamine secretion via secretory vesicle (ATP driven)
GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) SUBSYSTEM: N-Glycan Degradation
keratan sulfate I biosynthesis, precursor 22
UDPGlcA endoplasmic reticulum transport via UMP antiport_fwd
intracellular transport (peroxisome)_fwd
GENE_ASSOCIATION: (10559.1) SUBSYSTEM: Transport, Golgi Apparatus
CMP-Sia Golgi transport via CMP antiport_bkwd
phosphatidylinositol 4,5-bisphosphate nuclear transport (diffusion)_bkwd
GENE_ASSOCIATION: (4353.1) SUBSYSTEM: Miscellaneous
GENE_ASSOCIATION: (8854.2) or (501.1) or (216.1) or (224.1) or (8854.3) or (223.1) or (8854.1) SUBSYSTEM: beta-Alanine metabolism
beta-Aminopropion aldehyde:NAD+ oxidoreductase
keratan sulfate I biosynthesis, precursor 23
H+/K+ gastric/non-gastric P-ATPase and ABC ATPase
GENE_ASSOCIATION: (495.1 and 496.1) SUBSYSTEM: Transport, Extracellular
11-beta-hydroxysteroid dehydrogenase type 2_bkwd
GENE_ASSOCIATION: (23236.2) or (23236.1) SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol 4-phosphate phospholipase C, nucleus
L-tryptophan transport in via sodium symport
GENE_ASSOCIATION: (10327.1) or (8574.1) or (10327.2) or (231.1) SUBSYSTEM: Pyruvate Metabolism
methenyltetrahydrofolate cyclohydrolase_bkwd
formate-tetrahydrofolate ligase, mitochondrial_fwd
GENE_ASSOCIATION: (25902.1) SUBSYSTEM: Folate Metabolism
L-alanine/glutamine reversible exchange_bkwd
Maltodextrin glucosidase (maltotriose), lysosome
chondroitin sulfate A proteoglycan protease, lysosome (endosome)
nicotinamide-nucleotide adenylyltransferase_fwd
GENE_ASSOCIATION: (349565.1) or (23057.1) or (23057.2) SUBSYSTEM: NAD Metabolism
digalsgalside hs intracellular transport_bkwd
GENE_ASSOCIATION: (5298.1) or (55361.1) or (5297.1) SUBSYSTEM: Glycerophospholipid Metabolism
glucuronate endoplasmic reticular transport
Deoxycytidine kinase, nuclear (ATP)_bkwd
N-acetylneuraminate transport into lysososme_bkwd
chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 3
formaldehyde transport via diffusion (mitochondrial)_bkwd
Se-adenosyl-seleno-L-methionine nuclear transport_fwd
phosphatidylinositol 4,5-bisphosphate phospholipase C
GENE_ASSOCIATION: (5244.1) or (5244.3) or (5244.2) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (26289.1) or (26289.2) SUBSYSTEM: Nucleotides
phosphatidylinositol-3-phosphate 3-phosphatase
GENE_ASSOCIATION: (8897.2) or (8897.3) or (8897.1) SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (1579.1) SUBSYSTEM: CYP Metabolism
keratan sulfate II (core 2-linked), degradation product 9
sphingomyelin intracellular transport_fwd
Valine reversible mitochondrial transport_bkwd
(R)-3-Hydroxybutanoate mitochondrial transport via H+ symport_bkwd
carnitine O-acetyltransferase, endolasmic reticulum_fwd
GENE_ASSOCIATION: (1384.3) SUBSYSTEM: Fatty Acid Metabolism
chondroitin sulfate C transport, extracellular to lysosome
pentadecanoate transport into the mitochondria
GENE_ASSOCIATION: (6697.1) SUBSYSTEM: Tetrahydrobiopterin
4-aminobutyrate transaminase, reversible (mitochondrial)_fwd
nucleoside-diphosphate kinase (ATP:IDP), nuclear_fwd
5alpha-Dihydrotestosterone glucuronide exchange
aldehyde dehydrogenase (phenylacetaldehyde, NADP)
GENE_ASSOCIATION: SUBSYSTEM: Propanoate Metabolism
GENE_ASSOCIATION: (4056.1) or (4259.1) or (4056.2) or (4258.1) SUBSYSTEM: Eicosanoid Metabolism
succinate transport via sodium symport_fwd
GENE_ASSOCIATION: (9058.1) SUBSYSTEM: Transport, Extracellular
inositol-1,3,4-trisphosphate 1-phosphatase
Prostaglandin-H2 D-isomerase [Precursor]_bkwd
chondroitin sulfate C (GalNAc6S-GlcA), degradation product 5
GENE_ASSOCIATION: (178.4) or (178.5) or (178.1) or (178.3) or (178.2) or (178.6) SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (6783.1) or (6817.4) or (6817.1) or (6817.3) or (6817.2) or (6817.5) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (2271.1) SUBSYSTEM: Citric Acid Cycle
L-alanine/L-threonine Na-dependent exchange (Ala-L in)
GENE_ASSOCIATION: (3034.1) SUBSYSTEM: Histidine Metabolism
inosine facilated transport in mitochondria_bkwd
Butyrate mitochondrial transport via proton symport, reversible_fwd
Glycine betaine transport via diffusion (mitochondria to cytosol)_bkwd
L-2-aminoadipate shuttle (cytosol/mitochondria)_bkwd
GENE_ASSOCIATION: (89874.1) SUBSYSTEM: Lysine Metabolism
(alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
GENE_ASSOCIATION: (9488.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
H3 mannosyltransferase, endoplasmic reticulum
GENE_ASSOCIATION: (55902.1) or (65985.1) or (55902.2) SUBSYSTEM: Propanoate Metabolism
GENE_ASSOCIATION: (64849.1) or (64849.2) SUBSYSTEM: Transport, Extracellular
trimethyl-L-lysine transport (ER to cytosol)
oligo-1,6-glucosidase (glygn4 -> glygn5), extracellular
estrone-3-sulfate transport via sodium cotransport
GENE_ASSOCIATION: (6554.1) SUBSYSTEM: Transport, Extracellular
Propanoyl-CoA:FAD 2,3-oxidoreductase, mitochondrial
GENE_ASSOCIATION: (10723.1) or (57468.1) or (9990.1) or (6560.1) SUBSYSTEM: Transport, Extracellular
L-cysteine/L-threonine Na-dependent exchange (Thr-L in)
GENE_ASSOCIATION: (1159.1) or (1160.1) SUBSYSTEM: Urea cycle/amino group metabolism
Thiamine diphosphate transport in via anion antiport, mitochondria
GENE_ASSOCIATION: (2710.2) or (2712.1) or (2710.1) or (2713.1) SUBSYSTEM: Glycerophospholipid Metabolism
H5 mannosyltransferase, endoplasmic reticulum
GENE_ASSOCIATION: (1553.1) or (1548.1) SUBSYSTEM: CYP Metabolism
L-Lactate dehydrogenase, cytosolic/mitochondrial
GENE_ASSOCIATION: (124637.1) SUBSYSTEM: Pyruvate Metabolism
L-isoleucine transport via diffusion (extracellular to cytosol)_bkwd
Methanol transporter, endoplasmic reticulum_fwd
L-serine/L-cysteine Na-dependent exchange (Ser-L in)
GENE_ASSOCIATION: (4329.1) or (7915.1) or (8659.1) or (5832.1) or (217.1) or (7915.2) or (219.1) or (8659.2) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
Glycolaldehyde dehydrogenase, mitochondrial
Fumarate:sulfite antiport, mitochondrial_bkwd
7-glutamyl-THF transport,m mitochondrial
GENE_ASSOCIATION: (2222.1) SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (22978.1) or (30833.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (343.1) SUBSYSTEM: Transport, Mitochondrial
Urea transport via facilitate diffusion_bkwd
GENE_ASSOCIATION: (6523.1) or (6563.1) or (6528.1) or (8170.1) SUBSYSTEM: Transport, Extracellular
glycine-cleavage complex (lipoamide), mitochondrial_bkwd
GENE_ASSOCIATION: (8703.1) or (8704.2) or (8704.1) or (2683.1) or (9334.1) SUBSYSTEM: Keratan sulfate biosynthesis
keratan sulfate II biosynthesis, precursor 1
endo-beta-N-acetylglucosaminidase, lysosomal
FORMULA: C37H70N3O34P3FULLRCO2FULLR2CO2X
keratan sulfate I biosynthesis, precursor 27
GENE_ASSOCIATION: (2517.1) SUBSYSTEM: Keratan sulfate degradation
FADH2 transporter, endoplasmic reticulum
chondroitin sulfate A (GalNAc4S-GlcA) proteoglycan exchange
UDP-GlcNAc Golgi transport via CMP antiport_bkwd
GENE_ASSOCIATION: (11046.1) SUBSYSTEM: Transport, Golgi Apparatus
GENE_ASSOCIATION: (4668.1) SUBSYSTEM: Keratan sulfate degradation
GENE_ASSOCIATION: (3795.1) or (3795.2) SUBSYSTEM: Fructose and Mannose Metabolism
Glutathione transport into mitochondria_fwd
GENE_ASSOCIATION: SUBSYSTEM: Glutathione Metabolism
5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial_bkwd
adenine facilated transport from lysosome_fwd
GENE_ASSOCIATION: (5860.1) SUBSYSTEM: Tetrahydrobiopterin
D-Serine/Glycine reversible exchange_bkwd
glucose-1,2-(2)[glucose-1,3]-mannose oligosaccharide
acn13acngalgbside hs intracellular transport_bkwd
glucose-6-phosphate dehydrogenase, endoplasmic reticulum_bkwd
bicarbonate transport (Na/HCO3 cotransport)_bkwd
Gamma-glutamyl hydrolase (5THF), lysosomal
Thiamine monophosphate transport in via anion antiport_bkwd
starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]}) exchange
adenosine facilated transport in mitochondria_bkwd
UDP-xylose:protein xylosyltransferase, endoplasmic reticulum
GENE_ASSOCIATION: (64131.1) or (64132.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 7
tetrahydrofolate transport via anion exchange_bkwd
GENE_ASSOCIATION: (166012.1) or (113189.1) or (50515.1) or (55501.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
GENE_ASSOCIATION: (54981.1) SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (6718.1) SUBSYSTEM: Bile Acid Biosynthesis
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
glucose 6-phosphate dehydrogenase, endoplasmic reticulum_fwd
AMP transporter, endoplasmic reticulum_fwd
GENE_ASSOCIATION: (1559.1) SUBSYSTEM: CYP Metabolism
aspartate N-acetyltransferase, mitochondrial
GENE_ASSOCIATION: SUBSYSTEM: Alanine and Aspartate Metabolism
fucose-1-phosphate guanylyltransferase_fwd
GENE_ASSOCIATION: SUBSYSTEM: Taurine and hypotaurine metabolism
GENE_ASSOCIATION: (2936.1) SUBSYSTEM: Glutamate metabolism
Gamma-glutamyl hydrolase (7DHF), extracellular
GENE_ASSOCIATION: (54480.1) or (337876.1) or (79586.1) and (22856.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
chondroitin glucuronyltransferase II, Golgi apparatus
hydrogen peroxide nuclear transport_bkwd
chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 1
GENE_ASSOCIATION: SUBSYSTEM: Pyruvate Metabolism
keratan sulfate II (core 4-linked), degradation product 4
nucleoside-diphosphate kinase (ATP:dADP)_fwd
5-glutamyl-THF transport,m mitochondrial
phosphatidylglycerol (homo sapiens) exchange
L-cysteine transport via diffusion (extracellular to cytosol)_fwd
Itaconate--CoA ligase (ADP-forming), mitochondrial_bkwd
keratan sulfate I, degradation product 29
sialyl galactosylgloboside (homo sapiens)
acetyl-CoA C-acyltransferase (decanoyl-CoA), peroxisomal
chondroitin sulfate C (GalNAc6S-GlcA), degradation product 3
phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)
hydroxypyruate transport, peroxisomal_bkwd
5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
L-hydroxyproline dehydrogenase (NAD), mitochondrial
alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
GENE_ASSOCIATION: (51179.1) or (54363.1) or (51179.2) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
GENE_ASSOCIATION: (9956.1) or (9951.1) or (222537.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
methylenetetrahydrofolate dehydrogenase (NADP)_fwd
uridine facilated transport from lysosome_fwd
adenosine facilated transport in cytosol_bkwd
glucose 6-phosphate endoplasmic reticular transport via diffusion_fwd
GENE_ASSOCIATION: (6582.2) or (6582.1) or (6580.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (10654.1) SUBSYSTEM: Cholesterol Metabolism
Sulfate derivative of norepinephrine exchange
Urea transport via facilitate diffusion_fwd
GENE_ASSOCIATION: (55191.1) SUBSYSTEM: NAD Metabolism
deoxyinosine transport via diffusion_bkwd
NAD transport, nuclear through pores_fwd
carnitine dimethyl nonanoyl transferase, revsible, peroxisomal_fwd
GENE_ASSOCIATION: (3614.1) or (3615.1) or (3614.2) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: SUBSYSTEM: Eicosanoid Metabolism
phosphatidylinositol 4-phosphate 5-kinase
GENE_ASSOCIATION: (26227.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (57379.1) SUBSYSTEM: Nucleotides
alanine-glyoxylate transaminase (irreversible), (peroxisomal)
GENE_ASSOCIATION: (189.1) SUBSYSTEM: Alanine and Aspartate Metabolism
D-proline reversible transport via proton symport_bkwd
N,N'-Diacetylchitobiosyldiphosphodolichol, human liver homolog
GENE_ASSOCIATION: (47.1) or (47.2) SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (7167.1) or (286016.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (219.1) or (8659.1) or (217.1) or (8659.2) SUBSYSTEM: Tryptophan metabolism
aldehyde dehydrogenase (indole-3-acetaldehyde, NAD), mitochondrial
GENE_ASSOCIATION: (1719.1) SUBSYSTEM: Folate Metabolism
L-Cysteate:2-oxoglutarate aminotransferase, mitochondrial_bkwd
L-Serine/Glycine reversible exchange_bkwd
keratan sulfate I biosynthesis, precursor 34
UDP-GlcNAc:N-acetyl-D-glucosaminyl diphosphodolichol N-acetyl-D-glucosaminyltransferase (uterus)
D-mannose transport via sodium cotransport_fwd
Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)
prostaglandin transport via bicarbonate countertransport_fwd
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
Lysine mitochondrial transport via ornithine carrier_bkwd
chondroitin sulfate E (GalNAc4,6diS-GlcA) proteoglycan
glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]}) exchange
bicarbonate transport (Na/HCO3 1:3 cotransport)_bkwd
ribonucleoside-diphosphate reductase (ADP)
L-cysteine/L-asparagine Na-dependent exchange (Asn-L in)
GENE_ASSOCIATION: (200010.1) or (159963.1) or (6526.1) or (125206.1) or (6524.1) SUBSYSTEM: Transport, Extracellular
glucose transport via sodium symport_bkwd
GENE_ASSOCIATION: (5297.1) or (55361.1) or (5298.1) SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol-5-phosphate 4-kinase
PHEACGLN extracellular transport via diffusion_fwd
aminomuconate-semialdehyde dehydrogenase
potassium transport via proton antiport_fwd
GENE_ASSOCIATION: (6511.1) or (6505.1) or (6507.1) or (6506.1) or (6512.1) SUBSYSTEM: Transport, Extracellular
L-aspartate transport via Na, H symport and K antiport
inosine facilated transport from lysosome_fwd
L-aminoadipate-semialdehyde dehydrogenase (NADH), mitochondrial
keratan sulfate I biosynthesis, precursor 17
L-isoleucine transport in via sodium symport
Type 2 lactosamine alpha-2,3-sialyltransferase
GENE_ASSOCIATION: (10402.1) SUBSYSTEM: Blood Group Biosynthesis
Acetoacetate mitochondrial transport via H+ symport_bkwd
retinol dehydrogenase (13-cis,NADH)_bkwd
Gamma-glutamyl hydrolase (10FTHF6GLU), lysosomal
L-cysteine/L-glutamine reversible exchanger_fwd
GENE_ASSOCIATION: (11253.1) SUBSYSTEM: N-Glycan Biosynthesis
mannosidase I, endoplasmic reticulum (g1m6masnB1-producing)
lactose transport from Golgi to extracellular (via vesicle)
bilirubin monoglucuronide transport via bicarbonate countertransport_fwd
formate-tetrahydrofolate ligase, mitochondrial_bkwd
Gamma-glutamyl hydrolase (6DHF), extracellular
Thiamine monophosphate transport, mitochondrial_bkwd
25-hydroxyvitamin D3 transport from cytoplasm
phosphate transport, endoplasmic reticulum_fwd
GENE_ASSOCIATION: (2544.1) SUBSYSTEM: Transport, Endoplasmic Reticular
L-threonine/glycine reversible exchange_bkwd
Electron transfer flavoprotein-ubiquinone oxidoreductase
GENE_ASSOCIATION: (2110.1) SUBSYSTEM: Fatty acid oxidation
GENE_ASSOCIATION: (79901.1) SUBSYSTEM: Heme Biosynthesis
Betaine transport (sodium symport) (2:1)_bkwd
24,25-Dihydroxyvitamin D3 transport from cytoplasm
testicular 17-beta-hydroxysteroid dehydrogenase
GENE_ASSOCIATION: (51478.1) SUBSYSTEM: Steroid Metabolism
COA transporter, endoplasmic reticulum_fwd
Perillyl aldehyde:NAD+ oxidoreductase (m)
GENE_ASSOCIATION: (8659.2) or (217.1) or (8659.1) or (219.1) SUBSYSTEM: Limonene and pinene degradation
GENE_ASSOCIATION: (256435.1) or (30815.1) or (81849.1) SUBSYSTEM: Sphingolipid Metabolism
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
GENE_ASSOCIATION: SUBSYSTEM: N-Glycan Degradation
phosphatidylinositol 3-phosphate 4-kinase
GENE_ASSOCIATION: (55361.1) or (5297.1) or (8394.1) or (23396.1) or (8395.1) or (5298.1) SUBSYSTEM: Inositol Phosphate Metabolism
4-oxo-retinoic acid transport, Nuclear_bkwd
keratan sulfate I biosynthesis, precursor 9
phosphatidylinositol-3,4-bisphosphate 4-phosphatase, nuclear
GENE_ASSOCIATION: (56548.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
H8 mannosyltransferase, endoplasmic reticulum
adenosine facilated transport in mitochondria_fwd
nicotinamide-nucleotide adenylyltransferase, mitochondrial
cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)
glutaryl-CoA dehydrogenase (mitochondria)
GENE_ASSOCIATION: (2639.1) or (2639.2) SUBSYSTEM: Tryptophan metabolism
keratan sulfate I, degradation product 12
Beta-alanine reversible mitochondrial transport (diffusion)_fwd
phosphatidylinositol-5-phosphate 4-kinase, nuclear
FORMULA: C57H104N2O37P2FULLRCO2FULLR2CO2
(trimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (M4C)
choline phosphate intracellular transport_fwd
GENE_ASSOCIATION: (5167.1) SUBSYSTEM: Riboflavin Metabolism
H4 phosphoethanolaminyl transferase, endoplasmic reticulum
GENE_ASSOCIATION: (23556.1) or (23556.2) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
GENE_ASSOCIATION: (8528.2) or (8528.1) SUBSYSTEM: Alanine and Aspartate Metabolism
cytidine facilated transport in mitochondria_bkwd
GENE_ASSOCIATION: (2805.1) SUBSYSTEM: Tyrosine metabolism
keratan sulfate I, degradation product 41
methylmalonyl-CoA epimerase/racemase_fwd
ribose transport in via proton symporter
5-Methyltetrahydrofolate transport via receptor binding and protolysis_fwd
Dolichol diphosphate, human uterine homolog
cytidylate kinase (dCMP,GTP),nuclear_bkwd
2-hydroxybutyrate cotransport with proton_fwd
thymidine transport (1:2 Na/Thymd cotransport)
NMN transport, nuclear trhough pore_bkwd
phosphatidylinositol nuclear transport (diffusion)_fwd
guanosine facilated transport in mitochondria_fwd
UDP-Xyl endoplasmic reticular transport via CMP antiport_bkwd
GENE_ASSOCIATION: (6817.4) or (6817.1) or (6817.3) or (6817.2) or (6817.5) SUBSYSTEM: Tyrosine metabolism
10-formyltetrahydrofolate-[Glu](5) exchange
GENE_ASSOCIATION: (9420.1) SUBSYSTEM: Bile Acid Biosynthesis
Dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase (liver)
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 4
3,4-Dihydroxyphenylacetaldehyde:NAD+ oxidoreductase
GENE_ASSOCIATION: (218.1) or (222.1) or (220.1) or (221.1) SUBSYSTEM: Tyrosine metabolism
retinyl ester hydrolase (11-cis), extracellular
S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase
GENE_ASSOCIATION: (438.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (80025.5) SUBSYSTEM: CoA Biosynthesis
5-methylthioribose-1-phosphate isomerase_fwd
glycophosphatidylinositol (GPI) anchor precursor (3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol) (H8)
FORMULA: C55H106N4O38P4FULLRCO2FULLR2CO2
D-Glucuronolactone:NAD+ oxidoreductase, mitochondrial
GENE_ASSOCIATION: (8659.2) or (217.1) or (8659.1) or (219.1) SUBSYSTEM: Ascorbate and Aldarate Metabolism
keratan sulfate I biosynthesis, precursor 30
GENE_ASSOCIATION: (5152.1) SUBSYSTEM: Nucleotides
3',5'-cyclic-nucleotide phosphodiesterase, Nucleus
GENE_ASSOCIATION: (492.1) or (491.1) or (490.1) or (493.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (224.1) SUBSYSTEM: Fatty Acid Metabolism
1-alpha-Vitamin D-24,25-hydroxylase (D2)
GENE_ASSOCIATION: (9153.1) or (64078.1) SUBSYSTEM: Transport, Extracellular
S-Adenosyl-L-homocysteine intracellular diffusion_bkwd
hydroxylated estrogen derivative transport_bkwd
UDP-GalNAc endoplasmic reticulum transport via CMP antiport_bkwd
acgagbside hs intracellular transport_fwd
GENE_ASSOCIATION: (5167.1) or (5169.1) or (5168.1) SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (79087.1) SUBSYSTEM: N-Glycan Biosynthesis
sphingosylphosphorylcholine transport (diffusion)_bkwd
acetyl-CoA C-acetyltransferase (octanoyl-CoA), peroxisomal
GENE_ASSOCIATION: (4548.1) SUBSYSTEM: Methionine Metabolism
cytochrome c oxidase, mitochondrial Complex IV
L-proline reversible transport via proton symport_bkwd
glycine reversible transport via sodium and chloride symport (3:1:1)_fwd
7-alpha,27-Dihydroxycholesterol exchange
Dolichol-phosphate phosphohydrolase, human (uterus)
superoxide anion transport via diffusion (mitochondria)_bkwd
S-Adenosyl-L-methionine intracellular diffusion_fwd
keratan sulfate I, degradation product 31
GENE_ASSOCIATION: (3712.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
acyl-CoA dehydrogenase (isovaleryl-CoA), mitochondrial
m8masn transport from ER to Golgi apparatus
GENE_ASSOCIATION: (8869.1) SUBSYSTEM: Sphingolipid Metabolism
Lactosylceramide alpha-2,3-sialyltransferase, Golgi apparatus
thymidine transport in via sodium symport
cytidylate kinase (dCMP,CTP),nuclear_bkwd
GENE_ASSOCIATION: SUBSYSTEM: beta-Alanine metabolism
L-cystine/glycine exchanger (cystine in)
GENE_ASSOCIATION: (6519.1 and 11136.1) SUBSYSTEM: Transport, Extracellular
L-serine/L-glutamine Na-dependent exchange (Ser-L in)
H3 phosphoethanolaminyl transferase, endoplasmic reticulum
keratan sulfate I biosynthesis, precursor 26
D-fructose transport in via uniport_bkwd
GENE_ASSOCIATION: (8714.3) or (8647.1) or (8714.2) or (8714.1) SUBSYSTEM: Transport, Extracellular
saccharopine dehydrogenase (NADP, L-lysine forming), mitochondrial
GENE_ASSOCIATION: (10157.1) SUBSYSTEM: Lysine Metabolism
purine-nucleoside phosphorylase (Deoxyadenosine)_bkwd
prostaglandine E2 transport (ATP-dependent)
chondroitin sulfate D proteoglycan protease, lysosome (endosome)
GENE_ASSOCIATION: (229.1) SUBSYSTEM: Galactose metabolism
D-Tagatose 1-phosphate D-glyceraldehyde-3-phosphate-lyase_fwd
Creatine transport to/from mitochondria via diffusion
proteolysis of apoC-Lys-btn, mitochondrial
GENE_ASSOCIATION: (100.1) SUBSYSTEM: Nucleotides
D-3-Amino-isobutanoate:pyruvate aminotransferase, mitochondrial_fwd
L-serine/L-threonine Na-dependent exchange (Thr-L in)
25-hydroxyvitamin D2 transport from mitochondria
GENE_ASSOCIATION: (6533.1) SUBSYSTEM: Transport, Extracellular
taurine transport (sodium symport) (2:1)_fwd
nucleoside-diphosphate kinase (ATP:UDP), mitochondrial_fwd
4-Hydroxyphenylacetaldehyde:NADP+ oxidoreductase_bkwd
2,3-dioxo-L-gulonate decarboxylase (L-xylonate-forming)
beta-carotene transport via diffusion_fwd
inositol 1,4-bisphosphate nuclear transport (diffusion)_bkwd
GENE_ASSOCIATION: (1723.1) SUBSYSTEM: Pyrimidine Biosynthesis
dihydoorotic acid dehydrogenase (quinone10)
GENE_ASSOCIATION: (10840.1) SUBSYSTEM: Fatty Acid Metabolism
g1m6masnB1 endoplasmic reticulum to Golgi transport
GENE_ASSOCIATION: (1591.1) SUBSYSTEM: Vitamin D
Glycolate dehydrogenase (NADP), mitochondrial
chondroitin sulfate B (IdoA2S-GalNAc4S), precursor 4
L-2-aminoadipate shuttle (cytosol/mitochondria)_fwd
superoxide anion transport via diffusion (nucleus)_fwd
acgbgbside hs intracellular transport_bkwd
1-alpha,24R,25-Vitamin D-hydroxylase (D3)
Triiodothyronine sulfate transport (diffusion)
xylitol dehydrogenase (D-xyulose-forming)_fwd
adenosine 3',5'-bisphosphate Golgi transport
deoyguanosine transport in mitochondria_fwd
hydrogen peroxide mitochondrial transport_bkwd
FORMULA: C9H16O9P2FULLRCO2FULLR2CO2FULLRCO2FULLR2CO2
N-Acetylneuraminate lyase (reversible)_bkwd
GENE_ASSOCIATION: (240.1) SUBSYSTEM: Eicosanoid Metabolism
trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (x)_fwd
(Gal)3 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1
keratan sulfate I, degradation product 13
GENE_ASSOCIATION: (5315.2) or (5313.2) or (5315.3) or (5313.1) or (113452.1) or (5315.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
reducing GlcNAc removed form of n2m2nmasn (w/o peptide)
Putrescine:oxygen oxidoreductase (deaminating)
GENE_ASSOCIATION: (26.1) or (314.1) or (8639.1) or (314.2) SUBSYSTEM: Arginine and Proline Metabolism
3,4-Dihydroxyphenylacetaldehyde:NADP+ oxidoreductase_bkwd
D-sorbitol dehydrogenase (D-fructose producing)
GENE_ASSOCIATION: (6652.1) SUBSYSTEM: Fructose and Mannose Metabolism
GENE_ASSOCIATION: (1103.4) or (1103.1) or (1103.3) or (1103.2) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (2181.1) SUBSYSTEM: Fatty acid activation
L-cysteine/L-asparagine Na-dependent exchange (Cys-L in)
keratan sulfate I, degradation product 5
keratan sulfate II (core 4-linked), degradation product 2
nucleoside-diphosphate kinase (ATP:dGDP)_bkwd
Deoxycytidine kinase, mitochondrial (ATP)_bkwd
keratan sulfate II (core4) transport, golgi to extracellular
B mannosyltransferase, endoplasmic reticulum
formaldehyde transport via diffusion (lysosomall)_fwd
D-lactate transport via proton symport_bkwd
hyaluronan biosynthesis, precursor 1 exchange
heparan sulfate transport, extracellular to lysosome
25-hydroxyvitamin D3 transport from mitochondria
choline transport via diffusion (cytosol to mitochondria)_bkwd
cytidylate kinase (CMP,dGTP),nuclear_bkwd
deoxyadenosine transport via diffusion_bkwd
L-sulfolactate dehydrogenase (NAD+), mitochondrial_bkwd
nucleoside-diphosphatase (UDP), endoplasmic reticulum
nucleoside-diphosphate kinase (ATP:CDP)_fwd
GENE_ASSOCIATION: (3029.1) or (84264.2) or (84264.1) SUBSYSTEM: Pyruvate Metabolism
taurine transport (sodium symport) (cytosol to peroxisome)_bkwd
GENE_ASSOCIATION: (2224.1) SUBSYSTEM: Cholesterol Metabolism
Fumarate:sulfate antiport, mitochondrial_bkwd
phosphate transporter, mitochondrial_bkwd
GENE_ASSOCIATION: (5250.4) or (5250.1) or (5250.3) or (5250.2) SUBSYSTEM: Transport, Mitochondrial
4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
GENE_ASSOCIATION: (4129.1) or (8639.1) or (26.1) or (314.2) or (314.1) or (4128.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (51805.1) SUBSYSTEM: Ubiquinone Biosynthesis
dihydroxydecaprenylbenzoate methyltransferase
GENE_ASSOCIATION: (64579.1) or (3340.1) or (9348.1) or (8509.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
GlcNAc N-deacetylase / N-sulfotransferase
betaine-aldehyde dehydrogenase, mitochondrial
selenate transport via sodium symport_bkwd
Dehydrodolichol phosphate, human uterine homolog
glycine-cleavage complex (lipoamide), mitochondrial_fwd
deoxyguanylate kinase (dGMP:dATP) (mitochondrial)_fwd
GENE_ASSOCIATION: (6580.1) or (6582.2) or (6582.1) SUBSYSTEM: Transport, Extracellular
carnitine O-acetyltransferase, endolasmic reticulum_bkwd
L-cysteine reversible transport via sodium symport
L-threonine/L-glutamine Na-dependent exchange (Thr-L in)
nucleoside-diphosphate kinase (ATP:IDP)_fwd
phosphate transport in/out via three Na+ symporter_bkwd
2-Hydroxybutyrate:NAD+ oxidoreductase_bkwd
GENE_ASSOCIATION: (5198.1) SUBSYSTEM: IMP Biosynthesis
phosphoribosylformylglycinamidine synthase
phosphoribosylaminoimidazolesuccinocarboxamide synthase_fwd
mannose efflux from endoplasmic reticulum
GENE_ASSOCIATION: (3155.1) SUBSYSTEM: Cholesterol Metabolism
keratan sulfate I, degradation product 20
2,6 dimethylheptanoly CoA carnitine transferase_fwd
Acetoacetate decarboxylation (irreversible), mitochondrial
phosphoribosylglycinamide formyltransferase_bkwd
GENE_ASSOCIATION: (8867.1) or (56623.1) or (4952.1) or (8871.1) or (8867.2) or (4952.2) or (3633.1) SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol-4,5-bisphosphate 5-phosphatase
GENE_ASSOCIATION: (54576.1) SUBSYSTEM: Steroid Metabolism
UDP-glucuronosyltransferase 1-10 precursor, microsomal_fwd
keratan sulfate II (core 4-linked), degradation product 3
GENE_ASSOCIATION: (383.1) SUBSYSTEM: Urea cycle/amino group metabolism
3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase_fwd
GENE_ASSOCIATION: (7166.1) or (121278.1) SUBSYSTEM: Tryptophan metabolism
L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
GENE_ASSOCIATION: (3990.1) SUBSYSTEM: Fatty Acid Metabolism
phosphate transport in/out via two Na+ symporter_bkwd
GENE_ASSOCIATION: (242.1) SUBSYSTEM: Eicosanoid Metabolism
GENE_ASSOCIATION: (122481.1) or (203.1) or (26289.1) or (26289.2) SUBSYSTEM: Nucleotides
keratan sulfate II biosynthesis, precursor 3
GENE_ASSOCIATION: (6898.1) or (2806.1) SUBSYSTEM: Phenylalanine metabolism
D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase_bkwd
saccharopine dehydrogenase (NAD, L-glutamate forming), mitochondrial
GENE_ASSOCIATION: (6582.1) or (6582.2) SUBSYSTEM: Transport, Extracellular
Platelet-activating factor acetylhydrolase
GENE_ASSOCIATION: (7941.1) SUBSYSTEM: Glycerophospholipid Metabolism
Creatine transport (sodium symport) (2:1)_fwd
guanylate kinase (GMP:ATP), mitochondrial_fwd
inositol-1,3,4,5-triphosphate 6-kinase, nucleus
GENE_ASSOCIATION: (4023.1) SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (1545.1) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (8443.1) SUBSYSTEM: Triacylglycerol Synthesis
dihydroxyacetone phosphate acyltransferase
GENE_ASSOCIATION: (10020.1) or (55577.1) SUBSYSTEM: Aminosugar Metabolism
hydrogen peroxide mitochondrial transport_fwd
purine-nucleoside phosphorylase (Deoxyinosine)_fwd
Iodide:hydrogen-peroxide oxidoreductase 3
diphosphoinositol-1,3,4,6-tetrakisphosphate diphosphohydrolase, nucleus
GENE_ASSOCIATION: (10588.1) SUBSYSTEM: Folate Metabolism
5-formethyltetrahydrofolate cyclo-ligase
GENE_ASSOCIATION: (6470.1) or (6470.2) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
glycine hydroxymethyltransferase, reversible_bkwd
acetate mitochondrial transport via proton symport_fwd
keratan sulfate I biosynthesis, precursor 19
glycine passive transport to peroxisome_bkwd
chondroitin sulfate E (GalNAc4,6diS-GlcA) proteoglycan exchange
GENE_ASSOCIATION: (3251.1) SUBSYSTEM: Salvage Pathway
hypoxanthine phosphoribosyltransferase (Hypoxanthine)
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (mitochondria)_bkwd
GENE_ASSOCIATION: (3028.1) or (3033.1) or (3030.1) and (3032.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (113235.1) SUBSYSTEM: Transport, Extracellular
uridylate kinase (dUMP), mitochondrial_bkwd
Dolichyl-diphosphate phosphohydrolase, human (uterus)
GENE_ASSOCIATION: (57171.1) SUBSYSTEM: N-Glycan Biosynthesis
L-alanine/L-asparagine Na-dependent exchange (Asn-L in)
1-alkenyl 2-acylglycerol 3-phosphoethanolamine plasmalogen (homo sapiens)
10-Formyltetrahydrofolate mitochondrial transport via diffusion_bkwd
glucosaminyl-acylphosphatidylinositol ER flippase
dolichol-phosphate mannose flippase (uterus)
GENE_ASSOCIATION: (6647.1) SUBSYSTEM: ROS Detoxification
Dolichyl beta-D-glucosyl phosphate flippase (liver)
(R)-3-Hydroxybutanoate:NAD+ oxidoreductase_bkwd
H transporter, endoplasmic reticulum_fwd
3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase_fwd
GENE_ASSOCIATION: (218.1) or (221.1) or (222.1) or (220.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (9057.1 and 6520.1) SUBSYSTEM: Transport, Extracellular
(alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
(alpha-D-mannosyl)3-beta-D-mannosyl-diacetylchitodiphosphodolichol, human uterine homolog
nucleoside-diphosphate kinase (ATP:dGDP), nuclear_bkwd
L-glutamine reversible transport via sodium symport
m7masnB transport from endoplasmic reticulum to Golgi apparatus
keratan sulfate II biosynthesis, precursor 4
fatty acyl-CoA synthase (n-C8:0CoA), lumped reaction
glutathione transport via diffusion_bkwd
3,4-Dihydroxyphenylethyleneglycol exchange
L-alanine/L-cysteine Na-dependent exchange (Cys-L in)
GENE_ASSOCIATION: (19.1) SUBSYSTEM: Transport, Extracellular
nucleoside-diphosphate kinase (ATP:dIDP), mitochondrial_bkwd
GENE_ASSOCIATION: (23563.1) or (9435.1) or (10164.1) or (4166.1) or (23563.2) SUBSYSTEM: Keratan sulfate biosynthesis
carnitine O-acetyltransferase, reverse direction, peroxisomal_fwd
GENE_ASSOCIATION: (1384.2) SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (216.1) or (8854.1) or (224.1) or (8854.2) or (223.1) or (501.1) or (8854.3) SUBSYSTEM: Histidine Metabolism
GENE_ASSOCIATION: (10599.1) SUBSYSTEM: Transport, Extracellular
bilirubin beta-diglucuronide transport via bicarbonate countertransport_bkwd
dNAD transport, nuclear trhough pore_fwd
GENE_ASSOCIATION: (22978.1) SUBSYSTEM: Nucleotides
keratan sulfate II (core 2-linked), degradation product 1
dehydrodolichol diphosphate phosphatase (liver)
GENE_ASSOCIATION: (262.1) SUBSYSTEM: Arginine and Proline Metabolism
Gamma-glutamyl hydrolase (5DHF), extracellular
Thiamine transport in via proton symport, mitochondrial
N-acetylneuraminate transport into lysososme_fwd
GENE_ASSOCIATION: (56953.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (1718.1) SUBSYSTEM: Cholesterol Metabolism
24-dehydrocholesterol reductase [Precursor]
inositol-1,3,4,5,6-pentakisphosphate 2-kinase
L-Serine/Glutamine reversible exchange_bkwd
T3 transport via facilitated diffusion_bkwd
GENE_ASSOCIATION: (6567.1) SUBSYSTEM: Transport, Extracellular
3-sulfinopyruvate hydrolase (spotaneous reaction)
4-trimethylaminobutyraldehyde dehydrogenase
GENE_ASSOCIATION: (223.1) SUBSYSTEM: Lysine Metabolism
cysteinesulfinate-aspartate mitochondrial shuttle_fwd
GENE_ASSOCIATION: (10165.1) or (8604.1) SUBSYSTEM: Transport, Mitochondrial
L-asparagine transport in via sodium symport
GENE_ASSOCIATION: (10948.1) SUBSYSTEM: Transport, Mitochondrial
UDPGlcA Golgi transport via UMP antiport_fwd
guanosine facilated transport from lysosome_bkwd
Malonyl-CoA Decarboxylase, mitochondrial
GENE_ASSOCIATION: (22978.1) or (93034.2) or (93034.1) SUBSYSTEM: Nucleotides
deoxyguanylate kinase (dGMP:dATP) (mitochondrial)_bkwd
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
GENE_ASSOCIATION: (4245.1) SUBSYSTEM: N-Glycan Biosynthesis
L-2-amino-3-oxobutanoate decarboxylation, mitochondrial (spontaneous)
GENE_ASSOCIATION: (5091.1) or (5091.2) SUBSYSTEM: Pyruvate Metabolism
chondroitin sulfate/heparan sulfate linkage region (GlcA-(Gal)2-Xyl-L-Ser (protein))
GENE_ASSOCIATION: (6307.1) or (50814.1) SUBSYSTEM: Cholesterol Metabolism
chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 2
keratan sulfate I biosynthesis, precursor 14
chondroitin sulfate precursor (GalNAc-GlcA-(Gal)2-Xyl-L-Ser (protein))
trans,trans,cis-Geranylgeranyl diphosphate
testicular 17-beta-hydroxysteroid dehydrogenase_bkwd
GENE_ASSOCIATION: (7299.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (8034.1) SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: (84720.2) and (5281.1) or (84720.1) and (5281.2) or (5281.1) and (84720.1) or (84720.2) and (5281.2) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
UDP-glucuronosyltransferase 1-10 precursor, microsomal_bkwd
pyruvate peroxisomal transport via proton symport_fwd
GENE_ASSOCIATION: (5106.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
Noradrenaline secretion via secretory vesicle (ATP driven)
N-Acetylneuraminate lyase (reversible)_fwd
(Gal)3 (Glc)1 (GlcNAc)2 (LFuc)3 (Cer)1 exchange
nucleoside-diphosphatase (UTP), extracellular
Glycolipid 1,2-alpha-D-mannosyltransferase (uterus)
hypoxanthine facilated transport from lysosome_bkwd
GENE_ASSOCIATION: (2629.4) or (2629.1) or (2629.3) or (2629.2) or (2629.5) SUBSYSTEM: Sphingolipid Metabolism
Nucleoside triphosphate pyrophosphorylase (itp)
GENE_ASSOCIATION: (3704.1) or (3704.2) SUBSYSTEM: Nucleotides
uridine facilated transport from lysosome_bkwd
Cytidine facilated transport from lysosome_fwd
GENE_ASSOCIATION: (10390.1) or (56994.1) SUBSYSTEM: Glycerophospholipid Metabolism
mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol-Protein (M4A)
FORMULA: C61H116N4O43P4FULLRCO2FULLR2CO2X
phosphatidylinositol 4,5-bisphosphate (Homo sapiens)
1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens) exchange
GENE_ASSOCIATION: (4143.1) or (27430.2 and 4144.1) or (27430.1 and 4144.1) SUBSYSTEM: Selenoamino acid metabolism
chloride transport via bicarbonate countertransport (2:1)
GENE_ASSOCIATION: (8574.1) or (10327.1) or (231.1) or (10327.2) SUBSYSTEM: Fructose and Mannose Metabolism
GENE_ASSOCIATION: (2821.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
ornithine mitochondrial transport via proton antiport_fwd
calcium / sodium antiporter (1:3), reversible_fwd
keratan sulfate I transport, golgi to extracellular
glucose-6-phosphate dehydrogenase, endoplasmic reticulum
galactocerebroside intracellular transport_bkwd
deoyguanosine transport via diffusion_bkwd
GENE_ASSOCIATION: (55089.1) or (81539.1) or (54407.1) SUBSYSTEM: Transport, Extracellular
D-Tagatose 1-phosphate D-glyceraldehyde-3-phosphate-lyase_bkwd
17-beta-hydroxysteroid dehydrogenase (type 7)
GENE_ASSOCIATION: (53947.1) SUBSYSTEM: Sphingolipid Metabolism
Lactosylceramide 4-alpha-galactosyltransferase
alpha 1,4-N-acetylglucosaminyltransferase, Golgi apparatus
GENE_ASSOCIATION: (51146.1) SUBSYSTEM: O-Glycan Biosynthesis
keratan sulfate I, degradation product 22
10-Formyltetrahydrofolate lysosomal transport via diffusion_fwd
cytidylate kinase (dCMP,dATP),nuclear_bkwd
L-serine/L-threonine Na-dependent exchange (Ser-L in)
keratan sulfate II biosynthesis, precursor 7
GENE_ASSOCIATION: (5959.1) or (8608.1) SUBSYSTEM: Vitamin A Metabolism
2-keto-4-methylthiobutyrate transamination
3-Hydroxykynurenamine:oxygen oxidoreductase(deaminating)(flavin-containing)
GENE_ASSOCIATION: (29926.2) or (29926.1) or (29925.2) or (29925.1) SUBSYSTEM: Fructose and Mannose Metabolism
mannose-1-phosphate guanylyltransferase (GDP)
GENE_ASSOCIATION: (8639.1) or (26.1) or (314.2) or (314.1) SUBSYSTEM: Tyrosine metabolism
L-erythro-4-Hydroxyglutamate:2-oxoglutarate aminotransferase 2, mitochondrial
androsterone intracellular transport_bkwd
5-Hydroxy-L-tryptophan:oxygen 2,3-dioxygenase (indole-decyclizing)
GENE_ASSOCIATION: (4125.1) SUBSYSTEM: N-Glycan Degradation
keratan sulfate I, degradation product 15
GENE_ASSOCIATION: (316.1) SUBSYSTEM: Vitamin B6 Metabolism
Inorganic triphosphate transport through nuclear pore_fwd
hydroxyphenylacetate transport via diffusion_bkwd
bilirubin transport via bicarbonate countertransport_fwd
cytochrome P450, family 7, subfamily A, polypeptide 1
GENE_ASSOCIATION: (1581.1) SUBSYSTEM: Bile Acid Biosynthesis
phosphatidylethanolamine (homo sapiens) exchange
sodium transport via diffusion (perioxisome)_bkwd
3-hydroxyacyl-CoA dehydratase (3-hydroxyisobutyryl-CoA) (mitochondria)_fwd
GENE_ASSOCIATION: (1588.1) or (1588.2) SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (55089.1) SUBSYSTEM: Transport, Extracellular
L-histidine transport via diffusion (extracellular to cytosol)
L-Citramalyl-CoA hydro-lyase, mitochondrial_bkwd
L-threonine/L-asparagine Na-dependent exchange (Asn-L in)
GENE_ASSOCIATION: SUBSYSTEM: Blood Group Biosynthesis
GENE_ASSOCIATION: (3030.1) and (3032.1) or (38.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (10678.1) SUBSYSTEM: Blood Group Biosynthesis
5-methyltetrahydrofolate transport via anion exchange_fwd
chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 3
GENE_ASSOCIATION: (4191.1) SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (30.1 and 51.2 and 1962.1) or (51.1 and 30.1 and 1962.1) or (51.1 and 3295.1 and 30.1) SUBSYSTEM: Fatty acid oxidation, peroxisome
glutamate dehydrogenase (NADP), mitochondrial_bkwd
chondroitin sulfate E transport, extracellular to lysosome
UDP-GalNAc Golgi transport via CMP antiport_fwd
phosphatidylinositol 3-phosphate 4-kinase, nuclear
GENE_ASSOCIATION: (66002.1) SUBSYSTEM: Eicosanoid Metabolism
fucgalgbside hs intracellular transport_bkwd
GENE_ASSOCIATION: (92745.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (116255.1) or (80168.1) SUBSYSTEM: Triacylglycerol Synthesis
thymine reversible transport via facilated diffusion_bkwd
omega hydroxy tetradecanoate (n-C14:0) exchange
GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (229.1) or (230.1) SUBSYSTEM: Fructose and Mannose Metabolism
2-oxoadipate shuttle (cytosol/mitochondria)_fwd
L-alanine/L-cysteine Na-dependent exchange (Ala-L in)
keratan sulfate II (core2) transport, golgi to extracellular
cytosine transport via facilated diffusion_bkwd
GENE_ASSOCIATION: (29958.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
dimethylglycine dehydrogenase, mitochondrial
GENE_ASSOCIATION: (3422.1) or (91734.1) SUBSYSTEM: Cholesterol Metabolism
phosphatidylinositol-3,4-bisphosphate 3-phosphatase, nuclear
GENE_ASSOCIATION: (51181.1) SUBSYSTEM: Pentose and Glucuronate Interconversions
glycine hydroxymethyltransferase, reversible_fwd
GENE_ASSOCIATION: (128.1) SUBSYSTEM: Tyrosine metabolism
methylenetetrahydrofolate dehydrogenase (NADP), mitochondrial_bkwd
L-alanine/L-serine Na-dependent exchange (Ser-L in)
mesaconate--CoA ligase (ADP-forming), mitochondrial_bkwd
cysteine transaminase (mitochondrial)_bkwd
keratan sulfate I biosynthesis, precursor 24
norepinephrine sulfate transport (diffusion)
UDP-Xyl Golgi transport via CMP antiport_fwd
L-Serine/Glycine reversible exchange_fwd
Core 4 beta6-GalNAc-transferase, Golgi apparatus
GENE_ASSOCIATION: (9245.1) SUBSYSTEM: O-Glycan Biosynthesis
GENE_ASSOCIATION: (366.1) SUBSYSTEM: Transport, Mitochondrial
L-lactate transport via diffusion (cytosol to mitochondria)
L-1-Pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-Hydroxyglutamate semialdehyde, mitochondrial_fwd
H6 phosphoethanolaminyl transferase, endoplasmic reticulum
GENE_ASSOCIATION: (27010.1) SUBSYSTEM: Thiamine Metabolism
guanosine facilated transport in cytosol_fwd
keratan sulfate I, degradation product 9
chondroitin sulfate D transport, extracellular to lysosome
GENE_ASSOCIATION: (1565.1) SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (8908.1) and (2998.1) or (2998.1) and (2992.1) or (2997.1) and (2992.1) or (8908.1) and (2997.1) SUBSYSTEM: Starch and Sucrose Metabolism
UDP-GalNAc endoplasmic reticulum transport via CMP antiport_fwd
cytidine facilated transport in mitochondria_fwd
L-Kynurenine:2-oxoglutarate aminotransferase
Glycolipid 1,6-alpha-D-mannosyltransferase (uterus)
Deoxycytidine kinase, nuclear (UTP)_bkwd
superoxide anion transport via diffusion (nucleus)_bkwd
glycine-cleavage complex (lipoylprotein), mitochondrial_bkwd
adenine reversible transport, cytosol_fwd
estradiol glucuronide transport via bicarbonate countertransport_bkwd
GENE_ASSOCIATION: (1431.1) or (1431.2) SUBSYSTEM: Citric Acid Cycle
Dopamine 3-0-sulfate transport (diffusion)
GENE_ASSOCIATION: (10050.1) or (10786.1) or (10246.1) or (6568.1) SUBSYSTEM: Transport, Extracellular
phosphate transport in/out via three Na+ symporter (irreversible)
keratan sulfate I biosynthesis, precursor 2
UDP-Glc endoplasmic reticulum transport via CMP antiport_bkwd
(Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1 exchange
guanosine transport in via sodium (1:2) symport
L-alanine reversible transport via proton symport (lysosome)_bkwd
T3 transport via facilitated diffusion_fwd
nucleoside-diphosphate kinase (ATP:UDP)_bkwd
deoxyuridine transport via diffusion_fwd
GENE_ASSOCIATION: (10905.1) or (57134.1) or (4121.1) SUBSYSTEM: N-Glycan Biosynthesis
chondroitin sulfate A (GalNAc4S-GlcA), degradation product 2
L-arginine transport in via sodium symport
dehydroepiandrosterone sulfate transport via bicarbonate countertransport_fwd
GENE_ASSOCIATION: (6822.1) or (6822.1) SUBSYSTEM: Steroid Metabolism
Beta-galactoside alpha-2,3-sialyltransferase, Golgi apparatus
GENE_ASSOCIATION: (7363.1) or (54575.1) or (54490.1) or (54576.1) SUBSYSTEM: Steroid Metabolism
Benzene transporter, endoplasmic reticulum_bkwd
nucleoside-diphosphate kinase (ATP:UDP), nuclear_bkwd
cytosine transport via facilated diffusion_fwd
GENE_ASSOCIATION: (23464.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (10841.1) or (10841.2) SUBSYSTEM: Folate Metabolism
cholesterol precursor intracellular transport_fwd
phosphate transport, endoplasmic reticulum_bkwd
GENE_ASSOCIATION: (4123.1) SUBSYSTEM: N-Glycan Degradation
keratan sulfate I, degradation product 14
glucuronate transport into lysososme_bkwd
1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
digalsgalside hs intracellular transport_fwd
(R)-3-Hydroxybutanoate transport via H+ symport_fwd
Acetoacetyl-CoA:acetate CoA-transferase_fwd
GENE_ASSOCIATION: (65985.1) SUBSYSTEM: Propanoate Metabolism
Acetylcholine secretion via secretory vesicle (ATP driven)
GENE_ASSOCIATION: (6572.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (1645.1) SUBSYSTEM: Steroid Metabolism
aldo-keto reductase family 1, member C1 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
GENE_ASSOCIATION: (80270.1) SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (8639.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)
GENE_ASSOCIATION: (54490.1) SUBSYSTEM: Steroid Metabolism
nucleoside-diphosphate kinase (ATP:dUDP), nuclear_fwd
keratan sulfate II (core 4-linked), degradation product 1
n2m2nmasn transport, Golgi to extracellular
5-diphosphatidylinositol pentakisphosphate nuclear transport (diffusion)_bkwd
D-glucose transport in via proton symport_bkwd
ribonucleoside-diphosphate reductase (CDP)
Pyridoxal 5'-phosphate transport via diffusion, mitochondrial_bkwd
adenosine facilated transport from lysosome_bkwd
GENE_ASSOCIATION: (247.1) or (246.1) SUBSYSTEM: Eicosanoid Metabolism
chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 3
GENE_ASSOCIATION: (54575.1) or (54576.1) SUBSYSTEM: Vitamin A Metabolism
cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (x)_bkwd
keratan sulfate I, degradation product 35
L-Cysteate:2-oxoglutarate aminotransferase_fwd
alpha-ketoglutarate/malate transporter_bkwd
keratan sulfate II biosynthesis, precursor 10
3-hydroxyacyl-CoA dehydrogenase (2-Methylacetoacetyl-CoA), mitochondrial_bkwd
L-phenylalanine transport via diffusion (extracellular to cytosol)_fwd
2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxopentanoate), mitochondrial
(Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1
GENE_ASSOCIATION: (954.1) or (954.2) or (953.1) or (956.1) or (955.1) or (957.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (51.1 and 30.1 and 1962.1) or (30.1 and 51.2 and 1962.1) or (51.1 and 3295.1 and 30.1) SUBSYSTEM: Fatty acid oxidation, peroxisome
chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 2
chondroitin sulfate C (GalNAc6S-GlcA), degradation product 1
UDP-GlcNAc:dolichol-phosphate GlcNAc phosphotransferase (liver)
GENE_ASSOCIATION: (23657.1 and 6520.1) SUBSYSTEM: Transport, Extracellular
UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase (uterus)
CO2 nuclear transport via diffusion_bkwd
6-glutamyl-DHF transport,m mitochondrial
chondroitin sulfate C (GalNAc6S-GlcA), precursor 2
GENE_ASSOCIATION: (1757.1) SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (160728.1) SUBSYSTEM: Transport, Extracellular
trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (m)_fwd
GENE_ASSOCIATION: (549.1) or (3030.1) and (3032.1) SUBSYSTEM: Limonene and pinene degradation
Gamma-glutamyl hydrolase (7DHF), lysosomal
3',5'-cyclic-nucleotide phosphodiesterase
T4 transport via facilitated diffusion_fwd
M4B phosphoethanolaminyl transferase, endoplasmic reticulum
cytidylate kinase (dCMP,dATP),nuclear_fwd
(alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
Thiocyanate transport via diffusion (cytosol to extracellular)
L-lactate reversible transport via proton symport_bkwd
GENE_ASSOCIATION: (501.1) or (8854.3) or (216.1) or (8854.2) or (223.1) or (8854.1) or (224.1) SUBSYSTEM: Tryptophan metabolism
5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase
UDP-Glc endoplasmic reticulum transport via CMP antiport_fwd
cytidylate kinase (CMP,dATP),nuclear_fwd
GENE_ASSOCIATION: (8854.2) or (501.1) or (216.1) or (224.1) or (8854.3) or (223.1) or (8854.1) SUBSYSTEM: Limonene and pinene degradation
nicotinamide-nucleotide adenylyltransferase
carbamoyl-phosphate synthase (glutamine-hydrolysing)
nucleoside-diphosphate kinase (ATP:CDP)_bkwd
O2 transport, endoplasmic reticulum_fwd
purine-nucleoside phosphorylase (Deoxyguanosine)_bkwd
H7 phosphoethanolaminyl transferase, endoplasmic reticulum
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
GENE_ASSOCIATION: (9334.1) or (2683.1) or (8704.1) or (8703.1) or (8704.2) SUBSYSTEM: N-Glycan Biosynthesis
FORMULA: C53H100N3O35P3FULLRCO2FULLR2CO2X
GENE_ASSOCIATION: (2717.1) SUBSYSTEM: Sphingolipid Metabolism
phosphoribosylaminoimidazole carboxylase_fwd
GENE_ASSOCIATION: SUBSYSTEM: Fructose and Mannose Metabolism
GENE_ASSOCIATION: (54675.1) SUBSYSTEM: Glycerophospholipid Metabolism
Acetyl-CoA:aralkylamine N-acetyltransferase
GENE_ASSOCIATION: (15.1) SUBSYSTEM: Tryptophan metabolism
ADP/ATP transporter, endoplasmic reticulum_fwd
GENE_ASSOCIATION: (3081.1) SUBSYSTEM: Tyrosine metabolism
Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
GENE_ASSOCIATION: (1962.1) or (3295.1) SUBSYSTEM: Tryptophan metabolism
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (peroxisome)_fwd
D-lactate transport via proton symport_fwd
Maltodextrin glucosidase (maltotriose), extracellular
GENE_ASSOCIATION: (2819.1) SUBSYSTEM: Glycerophospholipid Metabolism
glycerol-3-phosphate dehydrogenase (NAD)_fwd
GENE_ASSOCIATION: (1384.2) SUBSYSTEM: Carnitine shuttle
carnitine O-aceyltransferase, peroxisomal_fwd
GENE_ASSOCIATION: (1103.4) or (1103.2) or (1103.3) or (1103.1) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (2673.1) or (9945.1) SUBSYSTEM: Aminosugar Metabolism
glutamine-fructose-6-phosphate transaminase
GENE_ASSOCIATION: (7108.1) SUBSYSTEM: Cholesterol Metabolism
Nucleoside triphosphate pyrophosphorylase (ditp)
Thiocyanate transport via diffusion (mitochondrial)
(alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
GENE_ASSOCIATION: (427.1) or (427.2) SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (130013.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (2875.1) or (84706.1) SUBSYSTEM: Glutamate metabolism
Shlomi2011 - Warburg effect, metabolic model Using a genome-scale human metabolic network model accounting for stoichiometric and enzyme solvent capacity considerations, this model shows that the Warburg effect (a classical hallmark of cancer metabolism) is a direct consequence of the metabolic adaptation of cancer cells to increase biomass production rate. This model is described in the article: Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect. Shlomi T, Benyamini T, Gottlieb E, Sharan R, Ruppin E PLoS Computational Biology. 2011; 7(3):e1002018 Abstract: The Warburg effect - a classical hallmark of cancer metabolism - is a counter-intuitive phenomenon in which rapidly proliferating cancer cells resort to inefficient ATP production via glycolysis leading to lactate secretion, instead of relying primarily on more efficient energy production through mitochondrial oxidative phosphorylation, as most normal cells do. The causes for the Warburg effect have remained a subject of considerable controversy since its discovery over 80 years ago, with several competing hypotheses. Here, utilizing a genome-scale human metabolic network model accounting for stoichiometric and enzyme solvent capacity considerations, we show that the Warburg effect is a direct consequence of the metabolic adaptation of cancer cells to increase biomass production rate. The analysis is shown to accurately capture a three phase metabolic behavior that is observed experimentally during oncogenic progression, as well as a prominent characteristic of cancer cells involving their preference for glutamine uptake over other amino acids. This model is hosted on BioModels Database and identified by: MODEL1105100000 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.
Shlomi2011 - Warburg effect, metabolic model
L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) (ER)
GENE_ASSOCIATION: (5033.1) and (5034.1) or (8974.1) and (5034.1) SUBSYSTEM: Arginine and Proline Metabolism
UDPGlcA Golgi transport via UMP antiport_bkwd
Holocarboxylase (biotin covalent bound to Lys residue of apoC)
gp1calpha hs intracellular transport_fwd
6-phosphogluconolactonase, endoplasmic reticulum
cholesterol efflux (ATP depedent), golgi
GENE_ASSOCIATION: (19.1) SUBSYSTEM: Transport, Golgi Apparatus
GENE_ASSOCIATION: (1491.1) or (1491.2) SUBSYSTEM: Cysteine Metabolism
citrate transport via sodium symport_fwd
GENE_ASSOCIATION: (2739.1) SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (55907.1) SUBSYSTEM: Aminosugar Metabolism
succinate transport via sodium symport_bkwd
nucleoside-diphosphate kinase (ATP:GDP), nuclear_fwd
corticosterone intracellular transport_fwd
uracil transport via facilated diffusion_fwd
GENE_ASSOCIATION: (389015.1) or (6548.1) or (6550.1) or (6549.1) or (6553.1) SUBSYSTEM: Transport, Extracellular
sodium proton antiporter (H:NA is 1:1)_bkwd
mannosidase I, endoplasmic reticulum (g1m7masnB-producing)
clupanodonic acid (docosapentaenoic (n-3)) exchange
3-hydroxyisobutyrate dehydrogenase, mitochondrial_fwd
phosphatidylinositol 4-phosphate 3-kinase, nuclear
gluconolactonase, endoplasmic reticulum_bkwd
GENE_ASSOCIATION: (8714.1) or (8714.3) or (8714.2) SUBSYSTEM: Transport, Extracellular
Norepinephrine reversible transport in via sodium symport (1:2)_fwd
Gamma-glutamyl hydrolase (10FTHF7GLU), extracellular
Glycolipid 1,3-alpha-D-mannosyltransferase (liver)
GENE_ASSOCIATION: (85365.1) or (85365.2) SUBSYSTEM: N-Glycan Biosynthesis
carnitine transport peroxisome to mitochondria_bkwd
3-sulfino-alanine transaminase (irreversible), mitochondrial
nucleoside-diphosphate kinase (ATP:GDP)_fwd
N-acteylglutamate synthase, mitochondrial
GENE_ASSOCIATION: (162417.1) SUBSYSTEM: Urea cycle/amino group metabolism
retinol dehydrogenase (all-trans,NADPH)_fwd
chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 1
L-alanine/glycine reversible exchange_bkwd
dodecenoyl-Coenzyme A delta isomerase_bkwd
isopentenyl-diphosphate D-isomerase_bkwd
3,4-Dihydroxyphenylethyleneglycol transport (diffusion)_bkwd
GENE_ASSOCIATION: (847.1) SUBSYSTEM: Miscellaneous
beta-galactoside alpha-2,3-sialyltransferase (core 2)
keratan sulfate I biosynthesis, precursor 11
Dolichyl-diphosphate phosphohydrolase, human (liver)
glucose transport, endoplasmic reticulum_fwd
sucrose hydrolyzing enxyme, extracellular
GENE_ASSOCIATION: (6476.1) or (8972.1) SUBSYSTEM: Galactose metabolism
(Gal)6 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1 exchange
diphosphatidylinositol tetrakisphosphate nuclear transport (diffusion)_fwd
(phosphoethanolaminyl-dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (H7)
phosphatidylinositol-5-phosphate 3-kinase, endoplasmic reticulum
lactaldehyde dehydrogenase, mitochondrial
Fumarate:sulfite antiport, mitochondrial_fwd
GENE_ASSOCIATION: (1582.1) SUBSYSTEM: Bile Acid Biosynthesis
keratan sulfate I biosynthesis, precursor 28
GENE_ASSOCIATION: (8659.2) or (217.1) or (8659.1) or (219.1) SUBSYSTEM: beta-Alanine metabolism
beta-Aminopropion aldehyde:NAD+ oxidoreductase (m)
GENE_ASSOCIATION: (57127.1) or (6005.1) SUBSYSTEM: Transport, Extracellular
ammonia transport via proton antiport_bkwd
N-Acetylneuraminate 9-phosphate phosphohydrolase
Xylitol transport via passive diffusion_fwd
Acetoacetyl-CoA:acetate CoA-transferase_bkwd
25-hydroxyvitamin D2 transport from cytoplasm
GENE_ASSOCIATION: (318.1) or (318.3) or (318.2) SUBSYSTEM: Nucleotides
uridine facilated transport in mitochondria_fwd
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
chondroitin sulfate B transport, golgi to extracellular
GENE_ASSOCIATION: (4953.1) SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (8879.1) SUBSYSTEM: Sphingolipid Metabolism
Nucleoside triphosphate pyrophosphorylase (xtp)
GENE_ASSOCIATION: (7083.1) or (7084.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (3073.1 and 3074.1) or (3073.1) or (3074.1) SUBSYSTEM: Keratan sulfate degradation
L-lactate reversible transport via sodium symport_bkwd
GENE_ASSOCIATION: (3795.1) or (3795.2) SUBSYSTEM: Galactose metabolism
Dehydrodolichol phosphate, human liver homolog
GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1) SUBSYSTEM: Pentose and Glucuronate Interconversions
glycogen, structure 5 (glycogenin-2[1,4-Glc]) exchange
1-alkyl 2-acylglycerol 3-phosphoethanolamine
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
chondroitin sulfate C transport, golgi to extracellular
4-aminobutyrate reversible transport in via proton symport_bkwd
docosa-4,7,10,13,16-pentaenoyl carnitine
phosphopantothenoylcysteine decarboxylase
GENE_ASSOCIATION: (60490.1) SUBSYSTEM: CoA Biosynthesis
GENE_ASSOCIATION: (166785.1) SUBSYSTEM: Transport, Mitochondrial
cytidylate kinase (CMP),mitochondrial_fwd
GENE_ASSOCIATION: (132789.1) or (10007.1) SUBSYSTEM: Aminosugar Metabolism
retinol dehydrogenase (9-cis,NADPH)_bkwd
g1m8masn transport from endoplasmic reticulum to Golgi apparatus
5-Aminolevulinate mitochondrial transport_bkwd
GENE_ASSOCIATION: (3158.1) SUBSYSTEM: Cholesterol Metabolism
cholesterol ester (from FULLR2) exchange
D-Serine/Glycine reversible exchange_fwd
1-alkylglycerol 3-phosphate (homo sapiens)
isoleucine transaminase, mitochondrial_fwd
mesaconate--CoA ligase (ADP-forming), mitochondrial_fwd
GENE_ASSOCIATION: (1572.1) SUBSYSTEM: Eicosanoid Metabolism
GENE_ASSOCIATION: (2523.1) SUBSYSTEM: Sphingolipid Metabolism
calcium / sodium antiporter (1:3), reversible_bkwd
uronolactonase, endoplasmic reticulum_bkwd
nicotinate-nucleotide adenylyltransferase_fwd
Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis) exchange
((N-acetyl-D-glucosaminyl)4-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)
methylenetetrahydrofolate dehydrogenase (NAD)_bkwd
GENE_ASSOCIATION: (285216.1) or (80068.1) SUBSYSTEM: Folate Metabolism
chondroitin sulfate D (GlcNAc6S-GlcA2S) proteoglycan exchange
Phenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating)
GENE_ASSOCIATION: (3242.1) SUBSYSTEM: Phenylalanine metabolism
keratan sulfate I, degradation product 33
glyceraldehyde-3-phosphate dehydrogenase_bkwd
keratan sulfate I biosynthesis, precursor 32
GENE_ASSOCIATION: (6526.1) SUBSYSTEM: Transport, Extracellular
inositol transport via sodium symport_bkwd
GENE_ASSOCIATION: (8833.1) SUBSYSTEM: Nucleotides
acetyl-CoA acyltransferase (hexadecanoyl-CoA), peroxisomal
2,6 dimethylheptanoyl crn transport_bkwd
GENE_ASSOCIATION: (445.1) or (445.2) SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (788.1) or (788.1) SUBSYSTEM: Carnitine shuttle
Deoxycytidine kinase, mitochondrial (ATP)_fwd
Glutamate transport via Na, H symport and K antiport
T3 transport via bicarbonate countertransport_bkwd
phosphatidylinositol 3-phosphate 5-kinase
alcohol dehydrogenase (L-1,2-propanediol)
acgbgbside hs intracellular transport_fwd
GENE_ASSOCIATION: (6520.1) and (23428.1) or (6520.1) and (23428.2) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (5464.1) SUBSYSTEM: Oxidative Phosphorylation
NICRNT transport, nuclear trhough pore_fwd
inositol transport in via proton symport_fwd
GENE_ASSOCIATION: (114134.1) SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (55577.1) SUBSYSTEM: Aminosugar Metabolism
dihydrofolate reversible mitochondrial transport_fwd
glycine reversible transport via proton symport (lysosome)_bkwd
Endomannosidase (glc3man-producing), Golgi apparatus
cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
2,3,4,5-Tetrahydropyridine-2-carboxylate transport, peroxisomal_bkwd
GENE_ASSOCIATION: (27159.1) or (54682.1) or (1118.1) SUBSYSTEM: Aminosugar Metabolism
ubiquinol-6 cytochrome c reductase, Complex III
nucleoside-diphosphate kinase (ATP:dUDP), nuclear_bkwd
Dolichyl-phosphate D-mannosyltransferase (liver)
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA) (mitochondria)_bkwd
GENE_ASSOCIATION: (847.1) SUBSYSTEM: ROS Detoxification
phosphoribosylaminoimidazolecarboxamide formyltransferase_fwd
prostaglandine E1 transport (ATP-dependent)
Glycine secretion via secretory vesicle (ATP driven)
GENE_ASSOCIATION: (2517.1) SUBSYSTEM: N-Glycan Degradation
GENE_ASSOCIATION: (2752.1) or (51557.1) SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (22929.1) or (22928.1) SUBSYSTEM: Selenoamino acid metabolism
Diphosphate transporter, peroxisome_bkwd
4-hydroxyretinoic acid transport, Nuclear_fwd
cytidylate kinase (CMP,dCTP),nuclear_fwd
uridylate kinase (dUMP), mitochondrial_fwd
3MLDA extracellular transport via diffusion_fwd
methylcrotonoyl-CoA carboxylase, mitochondrial_bkwd
keratan sulfate I biosynthesis, precursor 21
chondroitin sulfate C (GalNAc6S-GlcA), degradation product 4
GENE_ASSOCIATION: (316.1) SUBSYSTEM: Tryptophan metabolism
5-Hydroxyindoleacetaldehyde:oxygen oxidoreductase
GENE_ASSOCIATION: (4846.1) or (4844.1) or (4842.1) or (4843.2) or (4843.1) or (4845.1) SUBSYSTEM: Arginine and Proline Metabolism
Nitric Oxide Synthase (intermediate forming)
fatty acyl-CoA desaturase (n-C22:5CoA -> n-C22:6CoA)
cholate transport via bicarbonate countertransport_bkwd
({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)
FORMULA: C59H110N3O40P3FULLRCO2FULLR2CO2
keratan sulfate I, degradation product 10
GENE_ASSOCIATION: (9380.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
Biotin reversible transport via proton symport_fwd
phosphate transporter, mitochondrial_fwd
GENE_ASSOCIATION: (80308.1) or (80308.2) SUBSYSTEM: Riboflavin Metabolism
GENE_ASSOCIATION: (7915.1) or (7915.2) SUBSYSTEM: Glutamate metabolism
succinate-semialdehyde dehydrogenase (NAD) reversible (mitochondrial)
1D-myo-Inositol 1,3,4,6-tetrakisphosphate nuclear transport (diffusion)_fwd
phosphatidylinositol 4-phosphate 3-kinase, endoplasmic reticulum
Cyanide transport via diffusion (mitochondrial)_fwd
glycogen, structure 1 (glycogenin-11[1,4-Glc])
2-keto-3-deoxy-D-glycero-D-galactononic acid 9-phosphate
(Gal)3 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1 exchange
N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R exchange
UDP-Gal Golgi transport via CMP antiport_fwd
nucleoside-diphosphate kinase (ATP:UDP), nuclear_fwd
GENE_ASSOCIATION: (7390.1) SUBSYSTEM: Heme Biosynthesis
GENE_ASSOCIATION: (11254.1) or (81539.1) or (54407.1) SUBSYSTEM: Transport, Extracellular
superoxide anion transport via diffusion (mitochondria)_fwd
keratan sulfate I, degradation product 16
cytidylate kinase (dCMP,dCTP),nuclear_fwd
L-cysteine/L-glutamine Na-dependent exchange (Gln-L in)
GENE_ASSOCIATION: (51380.1) or (2571.1) or (2572.1) or (2571.2) SUBSYSTEM: Taurine and hypotaurine metabolism
Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)
Acetylcholin transport, nuclear trhough pores_bkwd
peroxisomal lumped long chain fatty acid oxidation
GENE_ASSOCIATION: (3295.1 and 8310.1 and 30.1 and 1962.1) SUBSYSTEM: Fatty acid oxidation, peroxisome
5,6,7,8-Tetrahydrofolate transport, diffusion, lysosomal_bkwd
docosa-4,7,10,13,16-pentaenoic acid (n-6) exchange
Acetylcholin transport, nuclear trhough pores_fwd
glycine reversible transport via proton symport (lysosome)_fwd
Melatonin:oxygen 2,3-dioxygenase (indole-decyclizing)
3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase
inositol transport in via proton symport_bkwd
L-alanine/L-serine Na-dependent exchange (Ala-L in)
GENE_ASSOCIATION: (131669.1) SUBSYSTEM: Histidine Metabolism
nucleoside-diphosphate kinase (ATP:IDP), mitochondrial_fwd
glycerol-3-phosphate dehydrogenase (NAD)_bkwd
retinol dehydrogenase (all-trans,NADPH)_bkwd
gulonate dehydrogenase, endoplasmic reticulum_fwd
(Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1
GENE_ASSOCIATION: (2762.1) SUBSYSTEM: Fructose and Mannose Metabolism
L-leucine transport via diffusion (extracellular to cytosol)_bkwd
sialyl (1,3) sialyl (2,6) galactosylgloboside (homo sapiens) exchange
GENE_ASSOCIATION: (3295.1) SUBSYSTEM: Cholesterol Metabolism
glutathione peroxidase, mitochondria_bkwd
trans-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (m)_bkwd
(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform A (protein)
glucose-1-phosphate thymidylyltransferase
GENE_ASSOCIATION: (2181.1) or (2181.2) SUBSYSTEM: Fatty acid activation
keratan sulfate I biosynthesis, precursor 3
GENE_ASSOCIATION: (54187.1) SUBSYSTEM: Aminosugar Metabolism
N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating)
cytidylate kinase (CMP,dATP),nuclear_bkwd
L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
GENE_ASSOCIATION: (5053.1) SUBSYSTEM: Tyr, Phe, Trp Biosynthesis
keratan sulfate I biosynthesis, precursor 4
GENE_ASSOCIATION: (11283.1) SUBSYSTEM: Eicosanoid Metabolism
nucleoside-diphosphate kinase (ATP:dTDP), mitochondrial_bkwd
D-proline reversible transport via proton symport (lysosome)_fwd
alcohol dehydrogenase (D-1,2-propanediol)
S-adenosyl-L-homocysteine nuclear transport_fwd
GENE_ASSOCIATION: (2571.1) or (2572.1) or (2571.2) SUBSYSTEM: Glutamate metabolism
Hydroxymethylglutaryl-CoA reversible peroxisomal transport_fwd
S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase
GENE_ASSOCIATION: (6303.1) or (112483.1) SUBSYSTEM: Arginine and Proline Metabolism
2-Methylprop-2-enoyl-CoA (2-Methylbut-2-enoyl-CoA), mitochondrial_bkwd
ribonucleoside-diphosphate reductase (GDP)
GENE_ASSOCIATION: (5009.1) SUBSYSTEM: Urea cycle/amino group metabolism
ornithine carbamoyltransferase, irreversible
GENE_ASSOCIATION: (57818.1) or (2538.1) or (92579.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
glucose-6-phosphate phosphatase, edoplasmic reticular
beta-carotene transport via diffusion_bkwd
dolichol-phosphate mannose flippase (liver)
peptide (lysine) nuclear transport via diffusion_bkwd
2-deoxy-D-ribose 1-phosphate phosphorylase
coproporphyrinogen oxidase (O2 required)
GENE_ASSOCIATION: (1371.1) SUBSYSTEM: Heme Biosynthesis
alpha-N-Phenylacetyl-L-glutamine exchange
GENE_ASSOCIATION: (3293.1) SUBSYSTEM: Steroid Metabolism
citrulline mitochondrial transport via proton antiport_bkwd
GENE_ASSOCIATION: (9962.2) or (9963.1) or (9962.1) or (9963.2) SUBSYSTEM: Transport, Extracellular
L-ascorbate transport via proton symport_bkwd
keratan sulfate I biosynthesis, precursor 12
({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol-Protein (M4B)
FORMULA: C59H110N3O40P3FULLRCO2FULLR2CO2X
Histidine transport (Na, H coupled)_bkwd
Malate:sulfite antiport, mitochondrial_bkwd
cob(I)alamin adenosyltransferase, mitochondrial_fwd
3-hydroxyacyl-CoA dehydratase (3-hydroxyisobutyryl-CoA) (mitochondria)_bkwd
Vitamin D2 transport from mitochondria_fwd
((N-acetyl-D-glucosaminyl)5-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)
GENE_ASSOCIATION: (6389.1 and 6392.1 and 6391.1 and 6390.1) SUBSYSTEM: Citric Acid Cycle
cytidylate kinase (CMP,CTP),nuclear_bkwd
acetate mitochondrial transport via proton symport_bkwd
GENE_ASSOCIATION: (4351.1) SUBSYSTEM: Fructose and Mannose Metabolism
CoA transport in lysosome via diffusion_bkwd
L-cysteine/L-threonine Na-dependent exchange (Cys-L in)
bilirubin beta-diglucuronide transport via bicarbonate countertransport_fwd
protoporphyrinogen IX mitochondrial transport_fwd
bicarbonate transport (Cl-/HCO3- exchange)_bkwd
(alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
GENE_ASSOCIATION: (80162.1) SUBSYSTEM: Starch and Sucrose Metabolism
L-glutamine/L-asparagine Na-dependent exchange (Asn-L in)
phosphatidylinositol 4-phosphate nuclear transport (diffusion)_fwd
Biotin reversible transport via proton symport, mitochondria_fwd
keratan sulfate I, degradation product 21
GENE_ASSOCIATION: (28231.1) or (6578.1) or (28232.1) or (6579.1) SUBSYSTEM: Transport, Extracellular
10-formyltetrahydrofolate-[Glu](7) exchange
GENE_ASSOCIATION: (5834.1) or (5837.1) or (5836.1) SUBSYSTEM: Starch and Sucrose Metabolism
glycogen phosphorylase (glygn2 -> dxtrn)
gp1calpha hs intracellular transport_bkwd
GENE_ASSOCIATION: (2820.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
glycerol-3-phosphate dehydrogenase (FAD), mitochondrial
carnitine O-aceyltransferase, peroxisomal_bkwd
nucleoside-diphosphate kinase (ATP:dGDP), mitochondrial_bkwd
acetyl-CoA C-acetyltransferase, mitochondrial_bkwd
GENE_ASSOCIATION: (5476.1) and (2720.1) and (2588.1) and (4758.1) or (5476.1) and (2720.1) SUBSYSTEM: Sphingolipid Metabolism
(alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog
Glycine betaine transport via diffusion (mitochondria to cytosol)_fwd
Malate:thiosulfate antiport, mitochondrial_bkwd
Adrenaline secretion via secretory vesicle (ATP driven)
adenosine transport (1:2 Na/Adn cotransport)
(Gal)3 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1 exchange
cytochrome P450 lanosterol 14-alpha-demethylase
GENE_ASSOCIATION: (1595.1) SUBSYSTEM: Cholesterol Metabolism
nucleoside-diphosphate kinase (ATP:dCDP), mitochondrial_fwd
S-Adenosyl-L-methionine:amine N-methyltransferase (srtn)
GENE_ASSOCIATION: (11185.1) SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (4143.1) or (27430.2 and 4144.1) or (27430.1 and 4144.1) SUBSYSTEM: Methionine Metabolism
GENE_ASSOCIATION: (116285.1) SUBSYSTEM: Fatty acid activation
fatty-acid--CoA ligase (butanoate), mitochondrial
GENE_ASSOCIATION: SUBSYSTEM: Vitamin B12 Metabolism
chondroitin sulfate B proteoglycan protease, lysosome (endosome)
ornithine transaminase reversible (m)_bkwd
asparagine synthase (glutamine-hydrolysing)
GENE_ASSOCIATION: (440.1) or (440.3) or (440.2) SUBSYSTEM: Alanine and Aspartate Metabolism
nucleoside-diphosphate kinase (ATP:dADP), mitochondrial_fwd
GENE_ASSOCIATION: (271.2) or (270.1) or (271.1) or (272.1) or (271.3) SUBSYSTEM: Nucleotides
superoxide anion transport via diffusion (peroxisome)_bkwd
GENE_ASSOCIATION: (2650.1) SUBSYSTEM: O-Glycan Biosynthesis
Core 6 beta-GlcNAc-transferase A, Golgi apparatus
UDP-GlcNAc Golgi transport via CMP antiport_fwd
glycine-cleavage complex (lipoylprotein) irreversible, mitochondrial
(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
tyrosine transaminase, mitochondrial_bkwd
retinoyl glucuronide efflux (13-cis) from ER
L-glutamate 5-semialdehyde dehydratase (spontaneous)
(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)
ornithine mitochondrial transport exchange with citruline_fwd
GENE_ASSOCIATION: (978.1) or (57379.1) SUBSYSTEM: Pyrimidine Catabolism
keratan sulfate I, degradation product 32
galacglcgalgbside hs intracellular transport_fwd
GENE_ASSOCIATION: (8781.1) or (5723.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
deoxyadenosine transport via diffusion_fwd
methylenetetrahydrofolate dehydrogenase (NAD)_fwd
GENE_ASSOCIATION: (9334.1) or (2683.1) or (8703.1) or (8704.2) or (8704.1) SUBSYSTEM: Keratan sulfate biosynthesis
5alpha-Dihydrotestosterone sulfotransferase
GENE_ASSOCIATION: (6822.1) SUBSYSTEM: Steroid Metabolism
1-alpha-Vitamin D-24,25-hydroxylase (D3)
L-sulfolactate transport (cytosol to extracellular)
GENE_ASSOCIATION: (4249.1) SUBSYSTEM: N-Glycan Biosynthesis
alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase
GENE_ASSOCIATION: (410.1) SUBSYSTEM: Sphingolipid Metabolism
keratan sulfate II (core 2-linked), degradation product 5
mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol (M4A)
FORMULA: C61H116N4O43P4FULLRCO2FULLR2CO2
N-acetylglucosamine-6-phosphate synthase
GENE_ASSOCIATION: (64841.1) SUBSYSTEM: Aminosugar Metabolism
purine-nucleoside phosphorylase (Inosine)_bkwd
GENE_ASSOCIATION: (3906.1) and (2683.1) or (8704.2) or (8704.1) SUBSYSTEM: Galactose metabolism
UDPgalactose:D-glucose 4-beta-D-galactosyltransferase, Golgi apparatus
L-arginine transport via diffusion (extracellular to cytosol)
nucleoside-diphosphate kinase (ATP:dUDP)_bkwd
Gamma-glutamyl hydrolase (7THF), extracellular
dihydrofolate reversible mitochondrial transport_bkwd
H2 phosphoethanolaminyl transferase, endoplasmic reticulum
keratan sulfate I, degradation product 26
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA) (perioxisome)_fwd
Linoleic acid (n-C18:2) transport in via diffusion_bkwd
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
GENE_ASSOCIATION: (4247.1) SUBSYSTEM: N-Glycan Biosynthesis
chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 5
dihomo-gamma-linolenic acid (n-6) exchange
keratan sulfate I biosynthesis, precursor 35
alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human uterine homolog
CoA transport in lysosome via diffusion_fwd
(alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
acn13acngalgbside hs intracellular transport_fwd
carnitine O-acetyltransferase, reverse direction, peroxisomal_bkwd
adenosine facilated transport in cytosol_fwd
inositol-1,4,5-trisphosphate 3-kinase, nucleus
GENE_ASSOCIATION: (221.1) or (222.1) SUBSYSTEM: Tyrosine metabolism
3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase_fwd
nucleoside-diphosphate kinase (ATP:IDP)_bkwd
GENE_ASSOCIATION: (55790.1) or (79586.1) and (22856.1) or (55454.1) or (337876.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
D-fructose transport via sodium cotransport_fwd
GENE_ASSOCIATION: (2745.1) or (51022.2) or (51022.1) SUBSYSTEM: Ascorbate and Aldarate Metabolism
GENE_ASSOCIATION: (114112.1) or (10587.1) or (10587.3) or (10587.2) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (2655.1) SUBSYSTEM: Glutathione Metabolism
chondroitin sulfate B transport, extracellular to lysosome
GENE_ASSOCIATION: (51.1) or (51.2) SUBSYSTEM: Fatty Acid Metabolism
acyl-CoA oxidase (hexadecanoyl-CoA), peroxisomal
Biotin reversible transport via proton symport, mitochondria_bkwd
cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)
keratan sulfate II (core 2-linked) exchange
24,25-Dihydroxyvitamin D2 transport from mitochondria
Glycolipid 1,6-alpha-D-mannosyltransferase (liver)
7-glutamyl-10FTHF transport, mitochondrial
keratan sulfate I, degradation product 4
GENE_ASSOCIATION: (158.1) or (158.2) SUBSYSTEM: Nucleotides
3-Mercaptolactate:NAD+ oxidoreductase_fwd
GENE_ASSOCIATION: (2109.2) and (2108.1) or (2109.1) and (2108.1) SUBSYSTEM: Fatty acid oxidation
taurine transport (sodium symport) (2:1)_bkwd
purine-nucleoside phosphorylase (Guanosine)_fwd
de-Fuc, reducing GlcNAc removed, de-Sia, de-Gal form of PA6 (w/o peptide linkage)
GENE_ASSOCIATION: (9227.1) SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (3073.1) or (3074.1) or (3073.1 and 3074.1) SUBSYSTEM: N-Glycan Degradation
UTP-glucose-1-phosphate uridylyltransferase_bkwd
GENE_ASSOCIATION: (7360.1) or (7359.1) or (7360.2) SUBSYSTEM: Galactose metabolism
FORMULA: C39H76N4O37P4FULLRCO2FULLR2CO2X
deacylated-glycophosphatidylinositol (GPI)-anchored protein
glutamate dehydrogenase (NAD) (mitochondrial)_bkwd
chondroitin sulfate D (GlcNAc6S-GlcA2S) precursor 2
N4-Acetylaminobutanal:NAD+ oxidoreductase (m)
GENE_ASSOCIATION: (217.1) or (8659.1) or (219.1) SUBSYSTEM: Arginine and Proline Metabolism
Endomannosidase (m5masnB1-producing), Golgi apparatus
GENE_ASSOCIATION: (1491.1) or (1491.2) SUBSYSTEM: Selenoamino acid metabolism
FOR transporter, endoplasmic reticulum_bkwd
nucleoside-diphosphate kinase (ATP:GDP), mitochondrial_fwd
GENE_ASSOCIATION: (2629.2) or (2629.3) or (2629.4) or (2629.5) or (2629.1) SUBSYSTEM: Sphingolipid Metabolism
acyl-CoA dehydrogenase (isobutyryl-CoA), mitochondrial
GENE_ASSOCIATION: (34.1) or (27034.1) SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
Nicotinamide adenine dinucleotide phosphate exchange
GENE_ASSOCIATION: (1576.1) SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (2651.1) SUBSYSTEM: Blood Group Biosynthesis
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
GENE_ASSOCIATION: (7299.1) SUBSYSTEM: Stilbene, coumarine and lignin biosynthesis
keratan sulfate I biosynthesis, precursor 33
L-serine/L-asparagine Na-dependent exchange (Asn-L in)
phosphatidylinositol 3,4-bisphosphate 5-kinase, nuclear
D-alanine transport via proton symport_bkwd
inositol-1,3,4,6-tetrakisphosphate 5-kinase, nucleus
chondroitin sulfate A transport, extracellular to lysosome
b-ketoacyl synthetase (palmitate, n-C16:0)
GENE_ASSOCIATION: (2954.1) or (2954.3) or (2954.2) SUBSYSTEM: Tyrosine metabolism
cytidylate kinase (CMP),mitochondrial_bkwd
GENE_ASSOCIATION: (1571.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
L-alanine reversible transport via proton symport (lysosome)_fwd
L-lysine transport in via sodium symport
GENE_ASSOCIATION: (11254.1) or (6584.1) SUBSYSTEM: Transport, Extracellular
purine-nucleoside phosphorylase (Xanthosine)_bkwd
L-ascorbate transport via proton symport_fwd
glycogen, structure 5 (glycogenin-2[1,4-Glc])
GENE_ASSOCIATION: (6916.1) SUBSYSTEM: Eicosanoid Metabolism
GENE_ASSOCIATION: SUBSYSTEM: Fatty acid activation
chloride transport via iodide countertransport
GENE_ASSOCIATION: (847.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (5051.1) or (5049.1 and 5050.1) or (5049.1 and 5050.1 and 5048.1) SUBSYSTEM: Glycerophospholipid Metabolism
Methylglyoxal transport (cytosol to extracellular)
Valine reversible mitochondrial transport_fwd
GENE_ASSOCIATION: (4166.1) or (10164.1) or (23563.2) or (23563.1) or (9435.1) SUBSYSTEM: Keratan sulfate biosynthesis
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
nucleoside-diphosphate kinase (ATP:dADP)_bkwd
GENE_ASSOCIATION: (7371.1) or (83549.1) SUBSYSTEM: Pyrimidine Biosynthesis
GENE_ASSOCIATION: (13.1) SUBSYSTEM: Alkaloid biosynthesis II
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (mitochondria)_fwd
chondroitin sulfate A (GalNAc4S-GlcA), degradation product 3
Vitamin D2 transport from mitochondria_bkwd
GENE_ASSOCIATION: (1503.1) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (100.1) SUBSYSTEM: Purine Catabolism
GENE_ASSOCIATION: (10317.4) or (10317.1) or (10317.3) or (10317.2) or (10317.5) SUBSYSTEM: Sphingolipid Metabolism
phosphate transport in/out via Na+ symporter_fwd
2-hydroxybutyrate cotransport with proton_bkwd
Malonyl-CoA-ACP transacylase, mitochondrial_bkwd
nucleoside-diphosphate kinase (ATP:dADP), nuclear_bkwd
keratan sulfate I biosynthesis, precursor 36
GENE_ASSOCIATION: (7296.3) or (7296.1) or (7296.4) or (7296.2) SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (80704.1) SUBSYSTEM: Transport, Extracellular
phosphatidylinositol phospholipase C, nucleus
superoxide anion transport via diffusion (peroxisome)_fwd
keratan sulfate II (core 4-linked) exchange
glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]}) exchange
3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase_bkwd
glycine hydroxymethyltransferase, reversible, mitochondrial_bkwd
Glutathione transport into mitochondria_bkwd
mannosyl-glucosaminyl-acylphosphatidylinositiol (H2)
GENE_ASSOCIATION: (51268.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
cytidylate kinase (dCMP,dGTP),nuclear_bkwd
sulfate transport via sodium symport_fwd
acetone mitochondrial transport via proton symport_bkwd
GENE_ASSOCIATION: (6783.1) or (6822.1) SUBSYSTEM: Steroid Metabolism
dehydrodolichol diphosphate phosphatase (uterus)
3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase_bkwd
(Gal)4 (Glc)1 (GlcNAc)3 (LFuc)3 (Cer)1 exchange
Malate:sulfate antiport, mitochondrial_fwd
phosphoethanolaminyl-mannosyl-glucosylaminyl-acylphosphatidylinositol (H5)
hydrogen peroxide peroxisomal transport via diffusion_fwd
acetoacetate intracellular transport unknown mechanism_bkwd
L-alanine reversible transport via proton symport_fwd
inositol 1,3,4,5,6-pentakisphosphate nuclear transport (diffusion)_bkwd
GENE_ASSOCIATION: (6999.1) SUBSYSTEM: Tryptophan metabolism
L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
5-Methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase
Beta-alanine reversible mitochondrial transport (diffusion)_bkwd
GENE_ASSOCIATION: (10390.1) SUBSYSTEM: Glycerophospholipid Metabolism
glyoxylate transport, mitochondrial_bkwd
D-alanine/glycine reversible exchange_fwd
fucosyl galactosylgloboside (homo sapiens) exchange
estradiol glucuronide transport via bicarbonate countertransport_fwd
N,N'-Diacetylchitobiosyldiphosphodolichol, human uterine homolog
9-O-Acetylated GT3 (homo sapiens) exchange
L-proline reversible transport via proton symport (lysosome)_bkwd
GENE_ASSOCIATION: (11320.1) or (11282.2) or (11282.1) SUBSYSTEM: N-Glycan Biosynthesis
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
GENE_ASSOCIATION: (57733.1) SUBSYSTEM: Stilbene, coumarine and lignin biosynthesis
beta-D-Glucosyl-2-coumarinate glucohydrolase
Tetradecanoate (n-C14:0) transport in via uniport
phosphatidylinositol-4-phosphate 4-phosphatase
L-ascorbate transport via facilitated diffusion_bkwd
GENE_ASSOCIATION: (64772.1) SUBSYSTEM: N-Glycan Degradation
L-alanine/L-asparagine Na-dependent exchange (Ala-L in)
3'-Phosphoadenylyl sufate Golgi transport_bkwd
GENE_ASSOCIATION: (347734.1) SUBSYSTEM: Transport, Golgi Apparatus
GENE_ASSOCIATION: (9615.1) SUBSYSTEM: Purine Catabolism
GENE_ASSOCIATION: (669.2) or (5223.1) or (5224.2) or (5224.1) or (669.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
cytochrome P450, family 46, subfamily A, polypeptide 1
GENE_ASSOCIATION: (10858.1) SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (10840.1) SUBSYSTEM: Folate Metabolism
Thiamine monophosphate transport in via anion antiport_fwd
Dehydrodolichol diphosphate, human liver homolog
6-glutamyl-THF transport,m mitochondrial
Hydroxymethylglutaryl-CoA reversible mitochondrial transport_bkwd
acn23acngalgbside intracellular transport_fwd
3-Methoxytyramine:oxygen oxidoreductase (deaminating)
9-O-Acetylated GD3 (homo sapiens) exchange
GENE_ASSOCIATION: (65220.1) SUBSYSTEM: NAD Metabolism
(Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1
chondroitin sulfate C proteoglycan protease, lysosome (endosome)
serine-pyruvate aminotransferase (irreversible), peroxisomal
GENE_ASSOCIATION: (189.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (4048.1) SUBSYSTEM: Eicosanoid Metabolism
GENE_ASSOCIATION: (3631.2) or (3631.1) or (8821.1) SUBSYSTEM: Inositol Phosphate Metabolism
Gamma-glutamyl hydrolase (10FTHF5GLU), extracellular
L-glutamate reversible transport via proton symport, mitochondrial_bkwd
GENE_ASSOCIATION: (5092.1) or (5092.2) SUBSYSTEM: Tetrahydrobiopterin
Tetrahydrobiopterin-4a-carbinolamine dehydratase
Proline transport (sodium symport) (2:1)_fwd
peptide (lysine) nuclear transport via diffusion_fwd
ethanol reversible peroxisomal transport_fwd
GENE_ASSOCIATION: (26.1) or (314.1) or (8639.1) or (314.2) SUBSYSTEM: Alkaloid biosynthesis II
N-Methylputrescine:oxygen oxidoreductase (deaminating)
glucose-6-phosphate dehydrogenase, endoplasmic reticulum_fwd
GENE_ASSOCIATION: (1644.1) SUBSYSTEM: Phenylalanine metabolism
2-keto-3deoxy-D-glycero-D-galactononic acid phosphohydrolase
2-methylcitrate transport via diffusion_fwd
UDP-Gal Golgi transport via CMP antiport_bkwd
phosphatidylserine (homo sapiens) exchange
D-aspartate transport via Na, H symport and K antiport
GENE_ASSOCIATION: (55349.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
choline dehydrogenase (FAD acceptor), mitochondrial
protoporphyrinogen IX mitochondrial transport_bkwd
13-cis-4-oxo-retinoic acid formation (oxidation)
uracil transport via facilated diffusion_bkwd
ornithine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (6542.1) or (6541.1) or (84889.1) SUBSYSTEM: Transport, Extracellular
cytidine transport (1:2 Na/cytd cotransport)
thromboxane A2 intracellular transport_fwd
GENE_ASSOCIATION: (9489.1) SUBSYSTEM: Glycerophospholipid Metabolism
phosphatidyl-CMP: glycerophosphate phosphatidyltransferase
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (peroxisome)_bkwd
mannosyl-oligosaccharide 1,2-alpha-mannosidase, endoplasmic reticulum
7-glutamyl-DHF transport,m mitochondrial
24,25-Dihydroxyvitamin D3 transport from mitochondria
5alpha-Dihydrotestosterone sulfate exchange
acn23acngalgbside intracellular transport_bkwd
GENE_ASSOCIATION: (11283.1) SUBSYSTEM: Cholesterol Metabolism
cytochrome P450 lanosterol 14-alpha-demethylase (NADP)
Tyrosine:dopa oxidase (dopaquinone producing 2)
GENE_ASSOCIATION: (4759.1) or (129807.1) SUBSYSTEM: N-Glycan Degradation
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5a
acnacngalgbside hs intracellular transport_bkwd
GENE_ASSOCIATION: (3295.1 and 30.1 and 51.2) or (30.1 and 51.2 and 1962.1) or (51.1 and 3295.1 and 30.1) or (51.1 and 30.1 and 1962.1) SUBSYSTEM: Fatty acid oxidation, peroxisome
Itaconate--CoA ligase (GDP-forming), mitochondrial_bkwd
(mannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (B)
GENE_ASSOCIATION: (9334.1) or (8704.1) or (8703.1) or (8704.2) or (2683.1) SUBSYSTEM: Keratan sulfate biosynthesis
4-methyl-2-oxopentanoate mitochondrial transport via proton symport
nucleoside-diphosphate kinase (ATP:CDP), mitochondrial_fwd
D-glucurono-6,3-lactone transport, endoplasmic reticulum_fwd
25-hydroxyvitamin D3 transport in mitochondria
thymidine facilated transport from lysosome_fwd
GENE_ASSOCIATION: (25796.1) SUBSYSTEM: Pentose Phosphate Pathway
aldehyde dehydrogenase (acetaldehyde, NAD)
nucleoside-diphosphate kinase (ATP:dIDP)_bkwd
hydroxypyruate transport, peroxisomal_fwd
GENE_ASSOCIATION: (29906.1) SUBSYSTEM: Blood Group Biosynthesis
GENE_ASSOCIATION: (6307.1) SUBSYSTEM: Cholesterol Metabolism
C-4 sterol methyl oxidase (4,4-dimethylzymosterol)
GENE_ASSOCIATION: (175.1) SUBSYSTEM: Keratan sulfate degradation
6-glutamyl-10FTHF transport, mitochondrial
nucleoside-diphosphate kinase (ATP:dADP), mitochondrial_bkwd
nucleoside-diphosphatase (GDP), extracellular
inositol-1,4,5-triphosphate 6-kinase, nucleus
(2)[glucose-1,3]-mannose oligosaccharide
GENE_ASSOCIATION: (8908.1) and (2997.1) or (2998.1) and (2992.1) or (2997.1) and (2992.1) or (8908.1) and (2998.1) SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (51268.1) SUBSYSTEM: Lysine Metabolism
L-arabinitol transport via passive diffusion
D-galactose transport via proton symport_fwd
L-4-hydroxyglutamate semialdehyde dehydrogenase, mitochondrial_fwd
GENE_ASSOCIATION: (1557.1) or (1543.1) or (1545.1) or (1544.1) SUBSYSTEM: Tryptophan metabolism
B-alanine secretion via secretory vesicle (ATP driven)
GENE_ASSOCIATION: (5238.1) SUBSYSTEM: Aminosugar Metabolism
galgalgalthcrm hs intracellular transport_bkwd
disialyl galactosylgloboside (homo sapiens) exchange
3,4-Dihydroxyphenylacetate:amet O-methyltransferase
2-Hydroxybutyrate:NAD+ oxidoreductase_fwd
GENE_ASSOCIATION: (26002.1) or (1621.1) SUBSYSTEM: Tyrosine metabolism
keratan sulfate I biosynthesis, precursor 18
GENE_ASSOCIATION: (3145.1) SUBSYSTEM: Heme Biosynthesis
GENE_ASSOCIATION: (210.1) or (210.2) SUBSYSTEM: Heme Biosynthesis
GENE_ASSOCIATION: (51166.1) or (51166.2) SUBSYSTEM: Lysine Metabolism
2-aminoadipate transaminase, irreversible
chondroitin sulfate D transport, golgi to extracellular
keratan sulfate I, degradation product 17
mannosidase II, endoplasmic reticulum (g1m6masnB1-producing)
GENE_ASSOCIATION: (53.1) SUBSYSTEM: CoA Catabolism
CMP-Sia Golgi transport via CMP antiport_fwd
sulfate transport via chloride countertransport (2:1)
Lysine mitochondrial transport via ornithine carrier_fwd
alkyl glycerol phosphate acyltransferase
estrone 3-sulfate transport via bicarbonate countertransport_fwd
chondroitin sulfate A (GalNAc4S-GlcA), degradation product 5
UTP-glucose-1-phosphate uridylyltransferase_fwd
GENE_ASSOCIATION: (53630.1) SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (10026.1) and (128869.1) and (8733.1) and (94005.1) and (51604.1) SUBSYSTEM: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
GENE_ASSOCIATION: (5409.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (10020.1) SUBSYSTEM: Aminosugar Metabolism
UDP-N-acetyl-D-glucosamine 2-epimerase (Hydrolysis)
O-acetylcarnintine transport into mitochondria via diffusion
L-alanine/L-glutamine Na-dependent exchange (Gln-L in)
GENE_ASSOCIATION: (10257.1) or (10057.2) or (10057.1) SUBSYSTEM: Transport, Extracellular
keratan sulfate I, degradation product 25
keratan sulfate I, degradation product 39
GENE_ASSOCIATION: (2990.1) SUBSYSTEM: Heparan sulfate degradation
D-alanine transport via proton symport (lysosome)_fwd
nucleoside-diphosphate kinase (ATP:dADP), nuclear_fwd
methylmalonate-semialdehyde dehydrogenase (malonic semialdehyde), mitochondrial
GENE_ASSOCIATION: (4329.1) SUBSYSTEM: Propanoate Metabolism
aldehyde dehydrogenase (indole-3-acetaldehyde, NAD)
GENE_ASSOCIATION: (216.1) or (8854.2) or (501.1) or (8854.1) or (223.1) or (224.1) or (8854.3) SUBSYSTEM: Tryptophan metabolism
inositol 1-phosphate nuclear transport (diffusion)_fwd
glycine reversible transport via sodium and chloride symport (2:1:1)_bkwd
NICRNT transport, nuclear trhough pore_bkwd
g3m8masn transport from endoplasmic reticulum to Golgi apparatus
pyrimidine-nucleoside phosphorylase (uracil)_bkwd
bilirubin transport via bicarbonate countertransport_bkwd
UDP-Glc Golgi transport via CMP antiport_bkwd
Gamma-glutamyl hydrolase (7THF), lysosomal
Core 7 alpha-GalNAc-transferase, Golgi apparatus
chondroitin sulfate A (GalNAc4S-GlcA), degradation product 4
keratan sulfate I, degradation product 3
phosphoethanolaminyl-trimannosyl-glucosaminyl-acylphosphatidylinositol (H6')
L-carnitine inward transport by Na+ symport
GENE_ASSOCIATION: (9468.1) or (5130.1) SUBSYSTEM: Glycerophospholipid Metabolism
chondroitin sulfate E transport, golgi to extracellular
gq1balpha hs intracellular transport_bkwd
guanosine transport in via sodium symport
GENE_ASSOCIATION: (219.1) or (8659.1) or (217.1) or (8659.2) SUBSYSTEM: Histidine Metabolism
Imidazole acetaldeyde dehydrogenase (mito)
keratan sulfate I, degradation product 36
N-acetyl-L-aspartate transport (mitochondria to cytosol)
uroporphyrinogen decarboxylase (uroporphyrinogen III)
GENE_ASSOCIATION: (7389.1) SUBSYSTEM: Heme Biosynthesis
V-type ATPase, H+ transporting, lysosomal
alpha-N-acetylglucosaminyltransferase I, Golgi apparatus
GENE_ASSOCIATION: (2137.1) or (2135.1) SUBSYSTEM: Chondroitin / heparan sulfate biosynthesis
H7' phosphoethanolaminyl transferase, endoplasmic reticulum
choline transport via diffusion (cytosol to mitochondria)_fwd
nucleoside-diphosphate kinase (ATP:dTDP)_bkwd
keratan sulfate I biosynthesis, precursor 13
starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]}) exchange
nucleoside-diphosphate kinase (ATP:GDP), nuclear_bkwd
Hydroxymethylglutaryl-CoA reversible mitochondrial transport_fwd
Linoleic acid (n-C18:2) transport in via diffusion_fwd
hydrogen peroxide lysosomal transport via diffusion_fwd
(alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog
2,6 dimethylheptanoly CoA carnitine transferase_bkwd
L-Cysteate:2-oxoglutarate aminotransferase, mitochondrial_fwd
pyruvate mitochondrial transport via proton symport_fwd
keratan sulfate I, degradation product 28
H7 mannosyltransferase, endoplasmic reticulum
GENE_ASSOCIATION: (1119.2) or (55500.1) or (1119.1) or (55224.1) SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (197258.1) SUBSYSTEM: Fructose and Mannose Metabolism
10-formyltetrahydrofolate-[Glu](6) exchange
L-Cysteate:2-oxoglutarate aminotransferase_bkwd
nucleoside-diphosphate kinase (ATP:dCDP)_fwd
dihydrofolate reversible lysosomal transport_fwd
L-valine transport in via sodium symport
GENE_ASSOCIATION: (1962.1) SUBSYSTEM: beta-Alanine metabolism
cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA hydro-lyase (m)_fwd
GENE_ASSOCIATION: (314.1) or (4128.1) or (26.1) or (4129.1) or (314.2) SUBSYSTEM: Phenylalanine metabolism
cysteinesulfinate-aspartate mitochondrial shuttle_bkwd
chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2
3'-Phosphoadenylyl sufate Golgi transport_fwd
5 alpha dihydrotesterone intracellular transport_fwd
D-proline reversible transport via proton symport (lysosome)_bkwd
GENE_ASSOCIATION: (51302.1) SUBSYSTEM: Bile Acid Biosynthesis
glucuronate transport into lysososme_fwd
Dolichol diphosphate, human liver homolog
GENE_ASSOCIATION: (7358.1) SUBSYSTEM: Starch and Sucrose Metabolism
3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase
GENE_ASSOCIATION: (221.1) or (218.1) or (220.1) SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (259230.1) SUBSYSTEM: Sphingolipid Metabolism
malate dehydrogenase, mitochondrial_bkwd
Glycolipid 1,3-alpha-D-mannosyltransferase (uterus)
keratan sulfate I, degradation product 18
GENE_ASSOCIATION: (6565.1) SUBSYSTEM: Transport, Extracellular
galacglcgalgbside hs intracellular transport_bkwd
GENE_ASSOCIATION: (6723.1) SUBSYSTEM: Urea cycle/amino group metabolism
T4 transport via facilitated diffusion_bkwd
GENE_ASSOCIATION: (10229.1) SUBSYSTEM: Ubiquinone Biosynthesis
retinol dehydrogenase (11-cis,NADH)_bkwd
L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase
GENE_ASSOCIATION: (1577.1) SUBSYSTEM: CYP Metabolism
4-aminobutyrate reversible transport in via proton symport_fwd
L-glutamate 5-semialdehyde dehydratase, reversible, mitochondrial_bkwd
GENE_ASSOCIATION: (118881.1) SUBSYSTEM: Tyrosine metabolism
farnesyltranstransferase (trans,trans,cis-geranylgeranyl diphosphate-generating)
dephospho-CoA transport from lysosome via diffusion_bkwd
nicotinamide-nucleotide adenylyltransferase_bkwd
keratan sulfate I, degradation product 30
GENE_ASSOCIATION: (1562.1) SUBSYSTEM: CYP Metabolism
ammonia transport via proton antiport_fwd