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notes: PMID: 16636147 PMID: 18198340 In response to hypoxia, REDD1 is induced and binds 14-3-3, resulting in TSC2/14-3-3 dissociation, TSC1/2 activation, and mTORC1 inhibition.
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notes: PMID: 15342917 Cell line: HEK293
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