COPASI15
is: CHEBI:17634
constant: false
boundary condition: false
has only substance units: false
initial concentration: 50.0
initial amount: NaN
in compartment: COPASI2
name: D-Glucose
type: Species

988111
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI36
modifier: 987714
reactant: 987654
fast: false
is described by: http://identifiers.org/ec-code/2.7.1.11
kinetic law: 987726
product: 987702
name: phosphofructokinase
reactant: 987666
product: 987690
reversible: true
is described by: http://identifiers.org/pubmed/3007939
product: 987678
type: Reaction

987786
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

987918
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

170093
value: 1.0
name: k4
type: LocalParameter

988243
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

170073
value: 1.0
name: k0
type: LocalParameter

COPASI26
constant: false
boundary condition: false
type: Species
is: P16861
name: YGR240C:YMR205C
initial amount: NaN
initial concentration: 0.00337856838203
in compartment: COPASI2
has only substance units: false
is: P16862

988183
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

COPASI8
is: CHEBI:15954
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Glucose 6-phosphate
type: Species

COPASI14
is: CHEBI:18367
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0
initial amount: NaN
in compartment: COPASI2
name: Phosphate
type: Species

987858
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

988159
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

987882
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

987930
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

COPASI37
reactant: 987738
is described by: http://identifiers.org/ec-code/5.3.1.9
product: 987750
reversible: true
is described by: http://identifiers.org/pubmed/8435847
type: Reaction
kinetic law: 987774
fast: false
modifier: 987762
name: glucose-6-phosphate isomerase

988015
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

170092
value: 1.0
name: k3
type: LocalParameter

987654
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

COPASI27
in compartment: COPASI2
constant: false
is: S000000400
initial amount: NaN
name: YBR196C
has only substance units: false
initial concentration: 0.01103966864816
is: P12709
boundary condition: false
type: Species

170082
value: 0.77
name: Km
type: LocalParameter

COPASI7
is: CHEBI:15946
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Fructose 6-phosphate
type: Species

170072
value: 4.13856
name: kcat
type: LocalParameter

987618
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

COPASI13
is: CHEBI:15846
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0
initial amount: NaN
in compartment: COPASI2
name: Nicotinamide adenine dinucleotide
type: Species

170089
value: 42.0
name: Vmax
type: LocalParameter

COPASI44
name: pyruvate decarboxylase
modifier: 988279
kinetic law: 988291
is described by: http://identifiers.org/ec-code/4.1.1.1
product: 988267
fast: false
reversible: true
reactant: 988231
type: Reaction
product: 988255
reactant: 988243

987702
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

170068
value: 4.0625E-5
name: Et
type: LocalParameter

COPASI38
name: phosphoglycerate kinase
is described by: http://identifiers.org/ec-code/2.7.2.3
reactant: 987786
is described by: http://identifiers.org/pubmed/6347186
modifier: 987834
reactant: 987798
reversible: true
product: 987810
kinetic law: 987846
type: Reaction
fast: false
product: 987822

988195
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI24
is: CHEBI:16526
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: CO2
type: Species

170081
value: 0.0
name: Vmax
type: LocalParameter

988255
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

170075
value: 1.9
name: Ki
type: LocalParameter

COPASI30
initial amount: NaN
is: P00360
name: YJL052W
boundary condition: false
is: S000003588
has only substance units: false
type: Species
constant: false
initial concentration: 0.03453452445155
in compartment: COPASI2

COPASI12
is: CHEBI:29052
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Glyceraldehyde 3-phosphate
type: Species

988099
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

COPASI43
is described by: http://identifiers.org/ec-code/2.7.1.40
reversible: true
type: Reaction
is described by: http://identifiers.org/pubmed/6185493
product: 988195
reactant: 988147
modifier: 988207
reactant: 988159
fast: false
name: pyruvate kinase
kinetic law: 988219
product: 988183
reactant: 988171

COPASI2
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: Cytoplasm
type: Compartment

170069
value: 0.450701
name: Ks
type: LocalParameter

COPASI39
fast: false
product: 987870
is described by: http://identifiers.org/ec-code/4.2.1.11
reversible: true
type: Reaction
is described by: http://identifiers.org/pubmed/7520111
reactant: 987858
modifier: 987894
kinetic law: 987906
product: 987882
name: enolase

170094
value: 1.0
name: k5
type: LocalParameter

COPASI9
is: CHEBI:16001
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 3-Phospho-D-glyceroyl phosphate
type: Species

COPASI25
boundary condition: false
constant: false
type: Species
is: P14540
initial concentration: 0.18915046668062
name: YKL060C
is: S000001543
initial amount: NaN
in compartment: COPASI2
has only substance units: false

COPASI11
is: CHEBI:17835
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Glycerate 2-phosphate
type: Species

170074
value: 0.0
name: I
type: LocalParameter

987666
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

COPASI23
is: CHEBI:15343
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Acetaldehyde
type: Species

988051
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

988039
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

COPASI42
is described by: http://identifiers.org/ec-code/5.4.2.1
modifier: 988123
kinetic law: 988135
reactant: 988099
is described by: http://identifiers.org/pubmed/3033435
product: 988111
name: phosphoglycerate mutase
type: Reaction
reversible: true
fast: false

988267
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

COPASI19
is: CHEBI:15361
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Pyruvate
type: Species

COPASI32
name: YKL152C
initial concentration: 0.06322939301798
is: P00950
type: Species
constant: false
boundary condition: false
is: S000001635
initial amount: NaN
has only substance units: false
in compartment: COPASI2

COPASI4
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: Extracellular
type: Compartment

987966
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

987738
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

987822
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

COPASI22
is: CHEBI:16908
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Nicotinamide adenine dinucleotide - reduced
type: Species

987954
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

COPASI10
is: CHEBI:16761
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: ADP
type: Species

170086
value: 48.0
name: Km
type: LocalParameter

COPASI41
reversible: true
is described by: http://identifiers.org/ec-code/2.7.1.1
modifier: 988075
fast: false
is described by: http://identifiers.org/pubmed/6394965
product: 988063
name: hexokinase (D-glucose:ATP)
kinetic law: 988087
product: 988051
reactant: 988015
product: 988039
reactant: 988027
type: Reaction

987798
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

COPASI18
is: CHEBI:18021
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Phosphoenolpyruvate
type: Species

MODEL1012110001
name: function_4_pyruvate kinase
species: COPASI8
function def: 170110
compartment: COPASI2
species: COPASI16
species: COPASI19
name: function_4_phosphoglycerate mutase
species: COPASI30
reaction: COPASI43
species: COPASI26
function def: 170116
name: function_4_phosphofructokinase
species: COPASI29
name: function_4_hexokinase (D-glucose:ATP)
reaction: COPASI37
function def: 170101
reaction: COPASI42
reaction: COPASI35
volume units: volume
function def: 170122
species: COPASI33
species: COPASI12
function def: 170119
species: COPASI21
reaction: COPASI38
species: COPASI15
name: function_4_glyceraldehyde-3-phosphate dehydrogenase
species: COPASI7
species: COPASI25
reaction: COPASI44
compartment: COPASI3
area units: area
species: COPASI18
is described by: http://identifiers.org/pubmed/21114840
species: COPASI10
species: COPASI32
species: COPASI28
function def: 170097
name: function_4_phosphoglycerate kinase
species: COPASI20
species: COPASI23
species: COPASI6
reaction: COPASI39
length unit: length
species: COPASI11
name: function_4_fructose-bisphosphate aldolase
function def: 170104
species: COPASI14
function def: 170113
function def: 170107
species: COPASI17
time units: time
name: function_4_enolase
compartment: COPASI4
species: COPASI24
species: COPASI9
name: function_4_pyruvate decarboxylase
name: Li2010_YeastGlycolysis
species: COPASI27
name: function_4_glucose-6-phosphate isomerase
curated: false
reaction: COPASI40
substance units: substance
notes: This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer toCC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. . To cite BioModels Database, please use:Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
species: COPASI31
type: SBMLModel
function def: 170098
species: COPASI34
reaction: COPASI36
reaction: COPASI41
species: COPASI13
species: COPASI22
species: COPASI5

988231
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

COPASI3
is: GO:0005886
constant: true
size: 1.0
spatial dimensions: 3.0
name: Plasma membrane
type: Compartment

COPASI31
is: P04806
is: S000001949
type: Species
constant: false
has only substance units: false
in compartment: COPASI2
initial amount: NaN
boundary condition: false
initial concentration: 0.00166468793545
name: YFR053C

988063
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

987606
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

COPASI21
is: CHEBI:15377
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: H2O
type: Species

988171
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

170085
value: 343.5
name: kcat
type: LocalParameter

COPASI40
reversible: true
reactant: 987918
product: 987954
name: glyceraldehyde-3-phosphate dehydrogenase
modifier: 987991
fast: false
reactant: 987942
reactant: 987930
kinetic law: 988003
product: 987966
product: 987979
type: Reaction
is described by: http://identifiers.org/ec-code/1.2.1.12
is described by: http://identifiers.org/pubmed/3905788

987594
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

170091
value: 1.0
name: k2
type: LocalParameter

COPASI35
is described by: http://identifiers.org/ec-code/4.1.2.13
kinetic law: 987642
is described by: http://identifiers.org/pubmed/8435847
reversible: true
type: Reaction
product: 987606
fast: false
modifier: 987630
reactant: 987594
name: fructose-bisphosphate aldolase
product: 987618

COPASI17
is: CHEBI:15378
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0
initial amount: NaN
in compartment: COPASI2
name: H+
type: Species

988027
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

987750
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

COPASI6
is: CHEBI:15422
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.5
initial amount: NaN
in compartment: COPASI2
name: ATP
type: Species

988147
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

987810
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

987870
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

987678
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

COPASI28
name: YCR012W
is: P00560
boundary condition: false
constant: false
initial amount: NaN
type: Species
has only substance units: false
is: S000000605
in compartment: COPASI2
initial concentration: 0.05511025068489

COPASI20
is: CHEBI:16108
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: Dihydroxyacetone phosphate
type: Species

170090
value: 1.0
name: k1
type: LocalParameter

COPASI16
is: CHEBI:17794
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 3-Phospho-D-glycerate
type: Species

987942
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

COPASI34
has only substance units: false
is: P06169
initial concentration: 0.09520868848003
boundary condition: false
constant: false
name: YLR044C
type: Species
in compartment: COPASI2
initial amount: NaN
is: S000004034

COPASI5
is: CHEBI:16905
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: D-Fructose 1,6-bisphosphate
type: Species

COPASI29
is: S000003486
in compartment: COPASI2
boundary condition: false
is: P00924
name: YGR254W
constant: false
initial amount: NaN
type: Species
initial concentration: 0.09259970021451
has only substance units: false

COPASI33
initial concentration: 0.29788672074056
type: Species
constant: false
initial amount: NaN
is: P00549
in compartment: COPASI2
name: YAL038W
has only substance units: false
is: S000000036
boundary condition: false

987979
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

170078
value: 0.86
name: Km
type: LocalParameter

987690
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference