383013
units: 304591
value: 0.0
type: LocalParameter

380031
units: 304591
value: 0.0
type: LocalParameter

313887
stoichiometry: 1.0
species: 378320
type: SpeciesReference

380554
units: 304591
value: 0.0
type: LocalParameter

319086
stoichiometry: 1.0
species: 378266
type: SpeciesReference

380345
units: 304591
value: -1000.0
type: LocalParameter

382275
units: 304591
value: 1000.0
type: LocalParameter

382389
units: 304591
value: 0.0
type: LocalParameter

378239
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide phosphate - reduced
type: Species

382324
units: 304591
value: 1000.0
type: LocalParameter

378368
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: pristanic acid
type: Species

321159
stoichiometry: 1.0
species: 378236
type: SpeciesReference

379401
reversible: false
reactant: 320799
notes: GENE_ASSOCIATION: (116255.1) or (80168.1) SUBSYSTEM: Triacylglycerol Synthesis
reactant: 320811
type: Reaction
kinetic law: 320847
product: 320823
fast: false
product: 320835
name: monoacylglycerolacyltransferase

382006
units: 304591
value: 0.0
type: LocalParameter

382654
units: 304591
value: 1000.0
type: LocalParameter

316550
stoichiometry: 1.0
species: 378125
type: SpeciesReference

381632
units: 304591
value: 1000.0
type: LocalParameter

383014
units: 304591
value: 0.0
type: LocalParameter

382549
units: 304591
value: 1000.0
type: LocalParameter

314882
stoichiometry: 1.0
species: 378191
type: SpeciesReference

308558
stoichiometry: 1.0
species: 378209
type: SpeciesReference

380030
units: 304591
value: 0.0
type: LocalParameter

383012
units: 304591
value: 13.5135135135135
type: LocalParameter

380625
units: 304591
value: -1000.0
type: LocalParameter

381381
units: 304591
value: 0.0
type: LocalParameter

308233
stoichiometry: 1.0
species: 378011
type: SpeciesReference

309584
stoichiometry: 1.0
species: 377772
type: SpeciesReference

323680
stoichiometry: 1.0
species: 377769
type: SpeciesReference

379626
kinetic law: 324622
reactant: 324610
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

380555
units: 304591
value: 0.0
type: LocalParameter

380344
units: 304591
value: 0.0
type: LocalParameter

382083
units: 304591
value: 0.0
type: LocalParameter

378711
kinetic law: 307281
product: 307269
reactant: 307257
reactant: 307245
notes: GENE_ASSOCIATION: (771.1) or (771.2) or (760.1) SUBSYSTEM: Miscellaneous
fast: false
reversible: true
name: carboxylicaciddissociation
type: Reaction

305889
stoichiometry: 1.0
species: 377933
type: SpeciesReference

378591
reactant: 304951
notes: GENE_ASSOCIATION: (5211.2) or (5213.1) or (5211.1) or (5211.1 and 5213.1) or (5213.1 and 5211.2) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
type: Reaction
product: 304976
product: 304963
kinetic law: 305000
reversible: false
name: phosphofructokinase
reactant: 304939
product: 304988

314079
stoichiometry: 1.0
species: 378401
type: SpeciesReference

377772
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: ATP
type: Species

381718
units: 304591
value: 0.0
type: LocalParameter

381384
units: 304591
value: 0.0
type: LocalParameter

378927
kinetic law: 311664
product: 311628
reactant: 311616
product: 311640
product: 311652
notes: GENE_ASSOCIATION: (9380.1) SUBSYSTEM: Pyruvate Metabolism
name: D-lactaldehydedehydrogenase
fast: false
reversible: true
reactant: 311604
type: Reaction

380628
units: 304591
value: 1000.0
type: LocalParameter

383011
units: 304591
value: 0.0
type: LocalParameter

312764
stoichiometry: 1.0
species: 378086
type: SpeciesReference

382273
units: 304591
value: -1000.0
type: LocalParameter

308341
stoichiometry: 1.0
species: 378083
type: SpeciesReference

382084
units: 304591
value: -1000.0
type: LocalParameter

379629
kinetic law: 324646
reactant: 324634
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382322
units: 304591
value: 0.0
type: LocalParameter

382656
units: 304591
value: 0.0
type: LocalParameter

307570
stoichiometry: 1.0
species: 377820
type: SpeciesReference

314211
stoichiometry: 1.0
species: 378059
type: SpeciesReference

382387
units: 304591
value: 1000.0
type: LocalParameter

382004
units: 304591
value: 0.0
type: LocalParameter

313114
stoichiometry: 1.0
species: 378227
type: SpeciesReference

380034
units: 304591
value: 1000.0
type: LocalParameter

381630
units: 304591
value: 0.0
type: LocalParameter

311275
stoichiometry: 1.0
species: 377984
type: SpeciesReference

320823
stoichiometry: 1.0
species: 377826
type: SpeciesReference

383010
units: 304591
value: 0.0
type: LocalParameter

382385
units: 304591
value: 0.0
type: LocalParameter

378714
product: 307329
kinetic law: 307341
product: 307317
notes: GENE_ASSOCIATION: (6389.1 and 6392.1 and 6391.1 and 6390.1) SUBSYSTEM: Citric Acid Cycle
reversible: true
type: Reaction
name: succinatedehydrogenase
reactant: 307293
reactant: 307305
fast: false

322817
stoichiometry: 1.0
species: 378059
type: SpeciesReference

382272
units: 304591
value: 0.0
type: LocalParameter

381930
units: 304591
value: -1000.0
type: LocalParameter

378651
kinetic law: 306144
product: 306132
reactant: 306120
reactant: 306108
notes: GENE_ASSOCIATION: (203.1) SUBSYSTEM: Nucleotides
fast: false
reversible: true
name: adenylatekinase
type: Reaction

313429
stoichiometry: 1.0
species: 378212
type: SpeciesReference

383249
units: 304591
value: 0.0
type: LocalParameter

306180
stoichiometry: 1.0
species: 377700
type: SpeciesReference

310501
stoichiometry: 1.0
species: 378221
type: SpeciesReference

380341
units: 304591
value: 0.0
type: LocalParameter

382154
units: 304591
value: -1000.0
type: LocalParameter

321063
stoichiometry: 1.0
species: 378059
type: SpeciesReference

324634
stoichiometry: 1.0
species: 378188
type: SpeciesReference

325768
stoichiometry: 1.0
species: 377880
type: SpeciesReference

381869
units: 304591
value: 1000.0
type: LocalParameter

320546
stoichiometry: 1.0
species: 377908
type: SpeciesReference

380558
units: 304591
value: 1000.0
type: LocalParameter

377778
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Bilirubin monoglucuronide
type: Species

380141
units: 304591
value: 0.0
type: LocalParameter

378594
kinetic law: 305049
product: 305037
product: 305025
reactant: 305012
notes: GENE_ASSOCIATION: SUBSYSTEM: Pyruvate Metabolism
fast: false
reversible: false
name: methylglyoxalsynthase
type: Reaction

379482
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
name: retinaldehydrogenase
product: 322213
product: 322238
product: 322226
type: Reaction
reactant: 322200
kinetic law: 322250
reversible: true
reactant: 322176
reactant: 322188

315231
stoichiometry: 1.0
species: 378458
type: SpeciesReference

382002
units: 304591
value: 1000.0
type: LocalParameter

323994
stoichiometry: 1.0
species: 378080
type: SpeciesReference

381636
units: 304591
value: 0.0
type: LocalParameter

379377
product: 320413
name: alcoholdehydrogenase(L-lactaldehyde)
reactant: 320365
type: Reaction
kinetic law: 320425
product: 320401
fast: false
product: 320389
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 320377
reversible: false

383248
units: 304591
value: 0.0
type: LocalParameter

382328
units: 304591
value: 0.0
type: LocalParameter

380621
units: 304591
value: 0.0
type: LocalParameter

307836
stoichiometry: 1.0
species: 378080
type: SpeciesReference

381932
units: 304591
value: 1000.0
type: LocalParameter

382270
units: 304591
value: 0.0
type: LocalParameter

382153
units: 304591
value: 0.0
type: LocalParameter

382000
units: 304591
value: -1000.0
type: LocalParameter

307414
stoichiometry: 1.0
species: 378218
type: SpeciesReference

381385
units: 304591
value: 0.0
type: LocalParameter

382329
units: 304591
value: 0.0
type: LocalParameter

378500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Threonine
type: Species

378236
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide phosphate - reduced
type: Species

383247
units: 304591
value: -1000.0
type: LocalParameter

308873
stoichiometry: 1.0
species: 377886
type: SpeciesReference

377850
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Cysteine
type: Species

378717
reactant: 307353
name: lactaldehydedehydrogenase
kinetic law: 307426
reactant: 307365
product: 307401
reversible: false
product: 307414
product: 307389
type: Reaction
notes: GENE_ASSOCIATION: (223.1) or (224.1) or (216.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 307377
fast: false

324346
stoichiometry: 1.0
species: 378569
type: SpeciesReference

321668
stoichiometry: 1.0
species: 378224
type: SpeciesReference

380624
units: 304591
value: 0.0
type: LocalParameter

381867
units: 304591
value: -1000.0
type: LocalParameter

381634
units: 304591
value: 0.0
type: LocalParameter

319556
stoichiometry: 1.0
species: 378548
type: SpeciesReference

317793
stoichiometry: 1.0
species: 378209
type: SpeciesReference

316224
stoichiometry: 1.0
species: 377700
type: SpeciesReference

377775
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Bilirubin monoglucuronide
type: Species

383246
units: 304591
value: 0.0
type: LocalParameter

382652
units: 304591
value: -1000.0
type: LocalParameter

382326
units: 304591
value: 0.0
type: LocalParameter

378233
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Nicotinamide adenine dinucleotide phosphate
type: Species

378503
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Threonine
type: Species

322685
stoichiometry: 1.0
species: 378326
type: SpeciesReference

311130
stoichiometry: 1.0
species: 378044
type: SpeciesReference

383244
units: 304591
value: 0.0
type: LocalParameter

382151
units: 304591
value: 0.0
type: LocalParameter

382081
units: 304591
value: 0.0
type: LocalParameter

315170
stoichiometry: 1.0
species: 378458
type: SpeciesReference

380140
units: 304591
value: 0.0
type: LocalParameter

381934
units: 304591
value: 0.0
type: LocalParameter

308910
stoichiometry: 1.0
species: 378077
type: SpeciesReference

312376
stoichiometry: 1.0
species: 378239
type: SpeciesReference

381388
units: 304591
value: 1000.0
type: LocalParameter

379374
fast: false
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
reversible: false
name: alcoholdehydrogenase(D-lactaldehyde)
reactant: 320304
product: 320340
product: 320328
product: 320316
reactant: 320292
kinetic law: 320353
type: Reaction

316972
stoichiometry: 1.0
species: 377951
type: SpeciesReference

319242
stoichiometry: 1.0
species: 378278
type: SpeciesReference

383245
units: 304591
value: 0.0
type: LocalParameter

379623
kinetic law: 324598
reactant: 324586
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382651
units: 304591
value: 0.0
type: LocalParameter

310659
stoichiometry: 1.0
species: 378272
type: SpeciesReference

379961
units: 304591
value: 0.0
type: LocalParameter

381405
units: 304591
value: -1000.0
type: LocalParameter

324707
stoichiometry: 1.0
species: 378122
type: SpeciesReference

306831
stoichiometry: 1.0
species: 378290
type: SpeciesReference

383166
units: 304591
value: 0.0
type: LocalParameter

313911
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381495
units: 304591
value: 0.0
type: LocalParameter

381937
units: 304591
value: 0.0
type: LocalParameter

320655
stoichiometry: 1.0
species: 378179
type: SpeciesReference

324851
stoichiometry: 1.0
species: 377763
type: SpeciesReference

309500
stoichiometry: 1.0
species: 378266
type: SpeciesReference

380498
units: 304591
value: 1000.0
type: LocalParameter

383243
units: 304591
value: -1000.0
type: LocalParameter

382380
units: 304591
value: 1000.0
type: LocalParameter

382540
units: 304591
value: 0.0
type: LocalParameter

382158
units: 304591
value: 0.0
type: LocalParameter

378657
reversible: true
kinetic law: 306264
type: Reaction
product: 306240
fast: false
reactant: 306216
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Nucleotides
product: 306252
name: purine-nucleosidephosphorylase(Adenosine)
reactant: 306228

382438
units: 304591
value: 0.0
type: LocalParameter

379960
units: 304591
value: 0.0
type: LocalParameter

379512
reversible: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism
type: Reaction
product: 322697
name: phosphatidylinositol-4-phosphate4-phosphatase,nuclear
kinetic law: 322709
fast: false
reactant: 322672
product: 322685
reactant: 322660

378029
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Guanine
type: Species

379485
product: 322323
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
reactant: 322262
product: 322298
reactant: 322286
name: retinaldehydrogenase(NADPH)
fast: false
reactant: 322274
type: Reaction
kinetic law: 322335
product: 322310
reversible: true

317685
stoichiometry: 3.0
species: 378209
type: SpeciesReference

319664
stoichiometry: 1.0
species: 378236
type: SpeciesReference

383165
units: 304591
value: 0.0
type: LocalParameter

381713
units: 304591
value: 0.0
type: LocalParameter

381494
units: 304591
value: 0.0
type: LocalParameter

318180
stoichiometry: 1.0
species: 378206
type: SpeciesReference

381936
units: 304591
value: 0.0
type: LocalParameter

383242
units: 304591
value: 0.0
type: LocalParameter

306240
stoichiometry: 1.0
species: 377688
type: SpeciesReference

305206
stoichiometry: 1.0
species: 378440
type: SpeciesReference

379515
kinetic law: 322745
product: 322733
reactant: 322721
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sphingosineintracellulartransport
type: Reaction

307075
stoichiometry: 1.0
species: 377616
type: SpeciesReference

379620
kinetic law: 324574
reactant: 324562
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

321378
stoichiometry: 1.0
species: 378431
type: SpeciesReference

379950
units: 304591
value: 0.0
type: LocalParameter

381525
units: 304591
value: 0.0
type: LocalParameter

379371
name: alcoholdehydrogenase(D-1,2-propanediol)
product: 320268
reactant: 320232
product: 320256
reversible: false
product: 320244
kinetic law: 320280
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 320220
type: Reaction
fast: false

381498
units: 304591
value: 1000.0
type: LocalParameter

316333
stoichiometry: 1.0
species: 377673
type: SpeciesReference

315062
stoichiometry: 1.0
species: 378236
type: SpeciesReference

378852
reversible: false
reactant: 309817
kinetic law: 309866
type: Reaction
notes: GENE_ASSOCIATION: (8574.1) or (231.1) or (10327.2) or (10327.1) SUBSYSTEM: Fructose and Mannose Metabolism
reactant: 309829
fast: false
name: D-sorbitolreductase
product: 309842
product: 309854
reactant: 309805

325600
stoichiometry: 1.0
species: 377631
type: SpeciesReference

381939
units: 304591
value: 1000.0
type: LocalParameter

383164
units: 304591
value: 0.0
type: LocalParameter

312268
stoichiometry: 1.0
species: 378071
type: SpeciesReference

325552
stoichiometry: 1.0
species: 377598
type: SpeciesReference

318072
stoichiometry: 1.0
species: 377847
type: SpeciesReference

309066
stoichiometry: 1.0
species: 378059
type: SpeciesReference

322006
stoichiometry: 1.0
species: 377901
type: SpeciesReference

383241
units: 304591
value: 0.0
type: LocalParameter

378125
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Isoleucine
type: Species

382542
units: 304591
value: 1000.0
type: LocalParameter

380494
units: 304591
value: 0.0
type: LocalParameter

382436
units: 304591
value: 1000.0
type: LocalParameter

309078
stoichiometry: 1.0
species: 378074
type: SpeciesReference

379951
units: 304591
value: 0.0
type: LocalParameter

382156
units: 304591
value: 1000.0
type: LocalParameter

316067
stoichiometry: 3.0
species: 378206
type: SpeciesReference

381524
units: 304591
value: 0.0
type: LocalParameter

381404
units: 304591
value: 0.0
type: LocalParameter

325091
stoichiometry: 1.0
species: 378299
type: SpeciesReference

383019
units: 304591
value: 0.0
type: LocalParameter

380408
units: 304591
value: 1000.0
type: LocalParameter

383163
units: 304591
value: -1000.0
type: LocalParameter

381711
units: 304591
value: 0.0
type: LocalParameter

383240
units: 304591
value: 0.0
type: LocalParameter

311021
stoichiometry: 1.0
species: 377661
type: SpeciesReference

380495
units: 304591
value: -1000.0
type: LocalParameter

383018
units: 304591
value: 0.0
type: LocalParameter

381401
units: 304591
value: 0.0
type: LocalParameter

311604
stoichiometry: 1.0
species: 378152
type: SpeciesReference

382658
units: 304591
value: 0.0
type: LocalParameter

379050
product: 314263
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
kinetic law: 314276
reactant: 314187
fast: false
name: 4-Pyridoxalsecretion
product: 314237
reactant: 314199
reversible: false
product: 314224
type: Reaction
reactant: 314211
product: 314250

378654
kinetic law: 306204
reversible: true
fast: false
product: 306192
reactant: 306156
type: Reaction
reactant: 306168
notes: GENE_ASSOCIATION: (4832.1) SUBSYSTEM: Nucleotides
name: nucleoside-diphosphatekinase(ATP:GDP)
product: 306180

382433
units: 304591
value: 0.0
type: LocalParameter

319134
stoichiometry: 1.0
species: 377826
type: SpeciesReference

305915
stoichiometry: 1.0
species: 377712
type: SpeciesReference

323572
stoichiometry: 1.0
species: 378575
type: SpeciesReference

379518
kinetic law: 322781
product: 322769
reactant: 322757
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sphinganineintracellulartransport
type: Reaction

382384
units: 304591
value: 0.0
type: LocalParameter

323106
stoichiometry: 1.0
species: 378101
type: SpeciesReference

313320
stoichiometry: 1.0
species: 377877
type: SpeciesReference

380405
units: 304591
value: 0.0
type: LocalParameter

381716
units: 304591
value: 1000.0
type: LocalParameter

307775
stoichiometry: 1.0
species: 377676
type: SpeciesReference

381491
units: 304591
value: 0.0
type: LocalParameter

311676
stoichiometry: 1.0
species: 378017
type: SpeciesReference

310381
stoichiometry: 1.0
species: 378338
type: SpeciesReference

378921
reactant: 311469
fast: false
name: alcoholdehydrogenase(ethanol,NADP),forwardreaction
product: 311507
reversible: false
product: 311519
notes: GENE_ASSOCIATION: (10327.1) or (10327.2) SUBSYSTEM: Glycolysis/Gluconeogenesis
kinetic law: 311532
reactant: 311481
type: Reaction
product: 311494

383017
units: 304591
value: 0.0
type: LocalParameter

314289
stoichiometry: 1.0
species: 378059
type: SpeciesReference

318204
stoichiometry: 1.0
species: 377691
type: SpeciesReference

306481
stoichiometry: 1.0
species: 377604
type: SpeciesReference

382434
units: 304591
value: 0.0
type: LocalParameter

314581
stoichiometry: 1.0
species: 377595
type: SpeciesReference

382279
units: 304591
value: 0.0
type: LocalParameter

379964
units: 304591
value: 1000.0
type: LocalParameter

382544
units: 304591
value: 0.0
type: LocalParameter

380348
units: 304591
value: 0.0
type: LocalParameter

380551
units: 304591
value: 0.0
type: LocalParameter

309283
stoichiometry: 1.0
species: 377769
type: SpeciesReference

379407
kinetic law: 320967
product: 320955
reactant: 320943
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: pristcoaperoxisomaltransport
type: Reaction

313779
stoichiometry: 1.0
species: 378314
type: SpeciesReference

324273
stoichiometry: 1.0
species: 377787
type: SpeciesReference

383169
units: 304591
value: 0.0
type: LocalParameter

383016
units: 304591
value: 13.5135135135135
type: LocalParameter

381521
units: 304591
value: 0.0
type: LocalParameter

379954
units: 304591
value: 1000.0
type: LocalParameter

379488
kinetic law: 322371
product: 322359
reactant: 322347
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: phosphatetransport,nuclear
type: Reaction

378128
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: myo-Inositol
type: Species

382431
units: 304591
value: 0.0
type: LocalParameter

313054
stoichiometry: 1.0
species: 377990
type: SpeciesReference

382547
units: 304591
value: 0.0
type: LocalParameter

325237
stoichiometry: 1.0
species: 378566
type: SpeciesReference

382382
units: 304591
value: 0.0
type: LocalParameter

310441
stoichiometry: 1.0
species: 377823
type: SpeciesReference

312425
stoichiometry: 1.0
species: 377613
type: SpeciesReference

309694
stoichiometry: 1.0
species: 377592
type: SpeciesReference

381714
units: 304591
value: -1000.0
type: LocalParameter

312981
stoichiometry: 1.0
species: 377754
type: SpeciesReference

383168
units: 304591
value: 13.5135135135135
type: LocalParameter

382659
units: 304591
value: -1000.0
type: LocalParameter

383015
units: 304591
value: 0.0
type: LocalParameter

320871
stoichiometry: 1.0
species: 377826
type: SpeciesReference

379404
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Fatty acid activation
name: fatty-acid--CoAligase
product: 320895
product: 320907
reactant: 320859
product: 320919
fast: false
type: Reaction
reactant: 320871
reversible: false
kinetic law: 320931
reactant: 320883

382277
units: 304591
value: 0.0
type: LocalParameter

382546
units: 304591
value: 0.0
type: LocalParameter

379967
units: 304591
value: 0.0
type: LocalParameter

378924
reactant: 311544
type: Reaction
notes: GENE_ASSOCIATION: (1644.1) SUBSYSTEM: Tryptophan metabolism
name: L-Tryptophandecarboxy-lyase
product: 311580
product: 311568
reversible: false
fast: false
reactant: 311556
kinetic law: 311592

323909
stoichiometry: 1.0
species: 377954
type: SpeciesReference

313210
stoichiometry: 1.0
species: 378071
type: SpeciesReference

380404
units: 304591
value: 0.0
type: LocalParameter

383167
units: 304591
value: -1000.0
type: LocalParameter

322188
stoichiometry: 1.0
species: 378212
type: SpeciesReference

318866
stoichiometry: 1.0
species: 378245
type: SpeciesReference

377628
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4-Pyridoxate
type: Species

306517
stoichiometry: 1.0
species: 377883
type: SpeciesReference

382441
units: 304591
value: -1000.0
type: LocalParameter

317939
stoichiometry: 1.0
species: 378299
type: SpeciesReference

323368
stoichiometry: 1.0
species: 378053
type: SpeciesReference

379053
type: Reaction
reactant: 314302
product: 314327
reactant: 314289
reversible: false
fast: false
name: phosphatidylinositol-4,5-bisphosphate4-phosphatase
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism
kinetic law: 314339
product: 314315

315801
stoichiometry: 1.0
species: 377969
type: SpeciesReference

316127
stoichiometry: 3.0
species: 378209
type: SpeciesReference

379278
kinetic law: 318542
product: 318530
reactant: 318518
notes: GENE_ASSOCIATION: (117247.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: L-tryptophantransport
type: Reaction

378131
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: myo-Inositol
type: Species

319942
stoichiometry: 1.0
species: 378374
type: SpeciesReference

322323
stoichiometry: 1.0
species: 378236
type: SpeciesReference

322213
stoichiometry: 1.0
species: 377574
type: SpeciesReference

380401
units: 304591
value: 0.0
type: LocalParameter

382440
units: 304591
value: 0.0
type: LocalParameter

379957
units: 304591
value: 0.0
type: LocalParameter

304951
stoichiometry: 1.0
species: 377905
type: SpeciesReference

377966
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Glutamine
type: Species

382908
units: 304591
value: 0.0
type: LocalParameter

379743
kinetic law: 325564
reactant: 325552
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: 25-HydroxyvitaminD3exchange
type: Reaction

382869
units: 304591
value: 0.0
type: LocalParameter

379164
kinetic law: 316574
product: 316562
reactant: 316550
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
type: Reaction

317477
stoichiometry: 1.0
species: 378206
type: SpeciesReference

304651
stoichiometry: 1.0
species: 378329
type: SpeciesReference

318712
stoichiometry: 1.0
species: 378209
type: SpeciesReference

312485
stoichiometry: 1.0
species: 378077
type: SpeciesReference

379479
kinetic law: 322164
product: 322152
reactant: 322140
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: glycolatetransportintoperoxisome
type: Reaction

379897
kinetic law: 326817
reactant: 326805
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: H2Oexchange
type: Reaction

382868
units: 304591
value: 0.0
type: LocalParameter

317225
stoichiometry: 1.0
species: 378056
type: SpeciesReference

381597
units: 304591
value: 0.0
type: LocalParameter

322973
stoichiometry: 1.0
species: 378212
type: SpeciesReference

379167
kinetic law: 316610
product: 316598
reactant: 316586
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
type: Reaction

316296
stoichiometry: 1.0
species: 377634
type: SpeciesReference

382988
units: 304591
value: 13.5135135135135
type: LocalParameter

307293
stoichiometry: 1.0
species: 377908
type: SpeciesReference

382989
units: 304591
value: 0.0
type: LocalParameter

305788
stoichiometry: 1.0
species: 378077
type: SpeciesReference

310973
stoichiometry: 4.0
species: 378077
type: SpeciesReference

378032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Gulono-1,4-lactone
type: Species

377960
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glucuronate
type: Species

380701
units: 304591
value: 0.0
type: LocalParameter

379809
kinetic law: 326093
reactant: 326081
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Ammoniaexchange
type: Reaction

381174
units: 304591
value: 0.0
type: LocalParameter

378858
product: 310006
product: 310018
reactant: 309980
name: 1-pyrroline-5-carboxylatedehydrogenase,mitochondrial
kinetic law: 310030
reversible: false
reactant: 309967
notes: GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Glutamate metabolism
product: 309994
type: Reaction
reactant: 309954
fast: false

383161
units: 304591
value: 0.0
type: LocalParameter

323897
stoichiometry: 1.0
species: 377853
type: SpeciesReference

308449
stoichiometry: 2.0
species: 378083
type: SpeciesReference

324055
stoichiometry: 1.0
species: 378161
type: SpeciesReference

382986
units: 304591
value: 0.0
type: LocalParameter

314436
stoichiometry: 1.0
species: 378482
type: SpeciesReference

379891
kinetic law: 326769
reactant: 326757
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: H+exchange
type: Reaction

323825
stoichiometry: 1.0
species: 377751
type: SpeciesReference

305170
stoichiometry: 1.0
species: 377933
type: SpeciesReference

318422
stoichiometry: 1.0
species: 378206
type: SpeciesReference

310864
stoichiometry: 2.0
species: 378284
type: SpeciesReference

382866
units: 304591
value: 0.0
type: LocalParameter

381288
units: 304591
value: 1000.0
type: LocalParameter

379746
kinetic law: 325588
reactant: 325576
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Pyridoxalexchange
type: Reaction

379161
kinetic law: 316538
product: 316525
reactant: 316513
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
type: Reaction

309138
stoichiometry: 1.0
species: 378059
type: SpeciesReference

314363
stoichiometry: 1.0
species: 378473
type: SpeciesReference

377625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-4-Hydroxyglutamate semialdehyde
type: Species

310212
stoichiometry: 1.0
species: 378065
type: SpeciesReference

383162
units: 304591
value: 0.0
type: LocalParameter

382987
units: 304591
value: 0.0
type: LocalParameter

377562
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: (R)-Propane-1,2-diol
type: Species

382752
units: 304591
value: 1000.0
type: LocalParameter

317501
stoichiometry: 1.0
species: 377796
type: SpeciesReference

381488
units: 304591
value: 1000.0
type: LocalParameter

378038
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Gulonate
type: Species

378134
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Inosine
type: Species

382904
units: 304591
value: 0.0
type: LocalParameter

319352
stoichiometry: 3.0
species: 378209
type: SpeciesReference

379749
kinetic law: 325612
reactant: 325600
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: 4-Pyridoxateexchange
type: Reaction

381285
units: 304591
value: -1000.0
type: LocalParameter

310151
stoichiometry: 1.0
species: 378083
type: SpeciesReference

326587
stoichiometry: 1.0
species: 377691
type: SpeciesReference

306300
stoichiometry: 1.0
species: 377604
type: SpeciesReference

313995
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382864
units: 304591
value: 13.5135135135135
type: LocalParameter

378855
kinetic law: 309941
fast: false
product: 309928
type: Reaction
product: 309915
reactant: 309902
reactant: 309878
notes: GENE_ASSOCIATION: (9615.1) SUBSYSTEM: Purine Catabolism
name: guaninedeaminase
reversible: false
reactant: 309890

382984
units: 304591
value: 13.5135135135135
type: LocalParameter

381528
units: 304591
value: 1000.0
type: LocalParameter

378035
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: L-Gulono-1,4-lactone
type: Species

381408
units: 304591
value: 1000.0
type: LocalParameter

378437
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Ribose
type: Species

381284
units: 304591
value: 0.0
type: LocalParameter

325019
stoichiometry: 1.0
species: 378092
type: SpeciesReference

377963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: D-Glucuronate
type: Species

381171
units: 304591
value: 0.0
type: LocalParameter

309476
stoichiometry: 2.0
species: 378281
type: SpeciesReference

312643
stoichiometry: 1.0
species: 378218
type: SpeciesReference

312050
stoichiometry: 1.0
species: 377769
type: SpeciesReference

383160
units: 304591
value: 0.0
type: LocalParameter

320715
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380781
units: 304591
value: 0.0
type: LocalParameter

377622
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: 4-Aminobutanoate
type: Species

382750
units: 304591
value: 0.0
type: LocalParameter

312837
stoichiometry: 2.0
species: 378281
type: SpeciesReference

382985
units: 304591
value: 0.0
type: LocalParameter

379894
kinetic law: 326793
reactant: 326781
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Phosphateexchange
type: Reaction

379056
product: 314387
reactant: 314351
name: sphingosinekinase2
reactant: 314363
notes: GENE_ASSOCIATION: (56848.1) SUBSYSTEM: Sphingolipid Metabolism
product: 314399
product: 314375
kinetic law: 314411
reversible: false
fast: false
type: Reaction

382906
units: 304591
value: 13.5135135135135
type: LocalParameter

320075
stoichiometry: 1.0
species: 377679
type: SpeciesReference

315740
stoichiometry: 1.0
species: 378500
type: SpeciesReference

381639
units: 304591
value: 1000.0
type: LocalParameter

378431
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Retinoate
type: Species

382901
units: 304591
value: 0.0
type: LocalParameter

382862
units: 304591
value: 0.0
type: LocalParameter

381378
units: 304591
value: 1000.0
type: LocalParameter

323716
stoichiometry: 1.0
species: 378386
type: SpeciesReference

380027
units: 304591
value: 0.0
type: LocalParameter

382757
units: 304591
value: -1000.0
type: LocalParameter

382982
units: 304591
value: 0.0
type: LocalParameter

323788
stoichiometry: 1.0
species: 377655
type: SpeciesReference

381866
units: 304591
value: 0.0
type: LocalParameter

380858
units: 304591
value: 1000.0
type: LocalParameter

380705
units: 304591
value: -1000.0
type: LocalParameter

381178
units: 304591
value: 1000.0
type: LocalParameter

382861
units: 304591
value: 0.0
type: LocalParameter

377555
constant: true
size: 1.0
spatial dimensions: 3.0
name: Endoplasmic_reticulum
type: Compartment

318312
stoichiometry: 1.0
species: 378206
type: SpeciesReference

382756
units: 304591
value: 0.0
type: LocalParameter

380134
units: 304591
value: 1000.0
type: LocalParameter

382983
units: 304591
value: 0.0
type: LocalParameter

306663
stoichiometry: 1.0
species: 377808
type: SpeciesReference

380704
units: 304591
value: 0.0
type: LocalParameter

378506
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Tryptophan
type: Species

382903
units: 304591
value: 0.0
type: LocalParameter

381637
units: 304591
value: 0.0
type: LocalParameter

378585
fast: false
product: 304843
reactant: 304795
notes: GENE_ASSOCIATION: (2597.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 304819
reversible: true
kinetic law: 304855
name: glyceraldehyde-3-phosphatedehydrogenase
reactant: 304807
product: 304831
reactant: 304783
type: Reaction

379272
product: 318446
reversible: true
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
reactant: 318434
fast: false
name: fattyacidelectroneutraltransport
reactant: 318422
type: Reaction
kinetic law: 318470
product: 318458

379059
type: Reaction
reactant: 314436
notes: GENE_ASSOCIATION: (81537.1) SUBSYSTEM: Sphingolipid Metabolism
name: sphingoidbase-phosphatephosphatase(sphinganine1-phosphatase),endoplasmicreticulum
reversible: false
reactant: 314423
product: 314448
kinetic law: 314472
fast: false
product: 314460

378242
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Nicotinamide adenine dinucleotide phosphate - reduced
type: Species

377565
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: (S)-Propane-1,2-diol
type: Species

377552
constant: true
size: 1.0
spatial dimensions: 3.0
name: Nucleus
type: Compartment

378371
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: pristanoyl coa
type: Species

317044
stoichiometry: 1.0
species: 378092
type: SpeciesReference

322431
stoichiometry: 1.0
species: 377799
type: SpeciesReference

380784
units: 304591
value: 0.0
type: LocalParameter

309368
stoichiometry: 1.0
species: 378077
type: SpeciesReference

377853
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Cysteine
type: Species

314666
stoichiometry: 1.0
species: 377601
type: SpeciesReference

381281
units: 304591
value: 0.0
type: LocalParameter

381864
units: 304591
value: 0.0
type: LocalParameter

378434
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Ribose
type: Species

382981
units: 304591
value: 0.0
type: LocalParameter

382754
units: 304591
value: 0.0
type: LocalParameter

309829
stoichiometry: 1.0
species: 378236
type: SpeciesReference

380785
units: 304591
value: -1000.0
type: LocalParameter

315958
stoichiometry: 1.0
species: 377954
type: SpeciesReference

380131
units: 304591
value: -1000.0
type: LocalParameter

382980
units: 304591
value: 13.5135135135135
type: LocalParameter

310598
stoichiometry: 1.0
species: 377712
type: SpeciesReference

381175
units: 304591
value: -1000.0
type: LocalParameter

306735
stoichiometry: 1.0
species: 377942
type: SpeciesReference

380855
units: 304591
value: 0.0
type: LocalParameter

379806
kinetic law: 326069
reactant: 326057
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Adenosineexchange
type: Reaction

319773
stoichiometry: 1.0
species: 378077
type: SpeciesReference

377856
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyadenosine
type: Species

379800
kinetic law: 326021
reactant: 326009
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Methionineexchange
type: Reaction

317587
stoichiometry: 1.0
species: 377802
type: SpeciesReference

377969
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Glutamine
type: Species

382333
units: 304591
value: 0.0
type: LocalParameter

378377
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Proline
type: Species

381862
units: 304591
value: 1000.0
type: LocalParameter

378509
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Tryptophan
type: Species

320607
stoichiometry: 1.0
species: 377862
type: SpeciesReference

322079
stoichiometry: 1.0
species: 377661
type: SpeciesReference

377559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 10-Formyltetrahydrofolate
type: Species

312533
stoichiometry: 1.0
species: 378077
type: SpeciesReference

380854
units: 304591
value: 0.0
type: LocalParameter

380024
units: 304591
value: 1000.0
type: LocalParameter

316695
stoichiometry: 1.0
species: 377853
type: SpeciesReference

320123
stoichiometry: 1.0
species: 378227
type: SpeciesReference

320763
stoichiometry: 1.0
species: 378236
type: SpeciesReference

382331
units: 304591
value: 1000.0
type: LocalParameter

317709
stoichiometry: 3.0
species: 378206
type: SpeciesReference

314822
stoichiometry: 1.0
species: 378206
type: SpeciesReference

323476
stoichiometry: 1.0
species: 378566
type: SpeciesReference

382086
units: 304591
value: 1000.0
type: LocalParameter

380708
units: 304591
value: 0.0
type: LocalParameter

305012
stoichiometry: 1.0
species: 377871
type: SpeciesReference

322104
stoichiometry: 1.0
species: 378305
type: SpeciesReference

315898
stoichiometry: 2.0
species: 378017
type: SpeciesReference

380137
units: 304591
value: 0.0
type: LocalParameter

379740
kinetic law: 325540
reactant: 325528
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Cystineexchange
type: Reaction

316815
stoichiometry: 1.0
species: 378173
type: SpeciesReference

307183
stoichiometry: 1.0
species: 378182
type: SpeciesReference

382759
units: 304591
value: 1000.0
type: LocalParameter

381860
units: 304591
value: -1000.0
type: LocalParameter

379803
kinetic law: 326045
reactant: 326033
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Inosineexchange
type: Reaction

326611
stoichiometry: 1.0
species: 377820
type: SpeciesReference

319460
stoichiometry: 1.0
species: 378056
type: SpeciesReference

305353
stoichiometry: 1.0
species: 377933
type: SpeciesReference

380788
units: 304591
value: 1000.0
type: LocalParameter

308727
stoichiometry: 1.0
species: 378356
type: SpeciesReference

377568
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 13-cis-oxo-retinoic acid
type: Species

378374
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: pristanoyl coa
type: Species

316019
stoichiometry: 3.0
species: 378209
type: SpeciesReference

321221
stoichiometry: 1.0
species: 378227
type: SpeciesReference

316755
stoichiometry: 1.0
species: 377619
type: SpeciesReference

377859
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Deoxyadenosine
type: Species

379275
kinetic law: 318506
product: 318494
reactant: 318482
notes: GENE_ASSOCIATION: (117247.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: L-tyrosinetransport
type: Reaction

378588
reactant: 304867
product: 304915
kinetic law: 304927
fast: false
reactant: 304879
reversible: false
notes: GENE_ASSOCIATION: (5315.2) or (5315.1) or (5315.3) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 304903
reactant: 304891
type: Reaction
name: pyruvatekinase

324128
stoichiometry: 1.0
species: 378338
type: SpeciesReference

382088
units: 304591
value: 0.0
type: LocalParameter

321439
stoichiometry: 2.0
species: 377574
type: SpeciesReference

380851
units: 304591
value: 0.0
type: LocalParameter

377558
constant: true
size: 1.0
spatial dimensions: 3.0
name: Peroxisome
type: Compartment

307606
stoichiometry: 1.0
species: 378269
type: SpeciesReference

380564
units: 304591
value: 0.0
type: LocalParameter

307401
stoichiometry: 1.0
species: 378146
type: SpeciesReference

382072
units: 304591
value: 0.0
type: LocalParameter

379617
kinetic law: 324550
reactant: 324538
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

380331
units: 304591
value: 0.0
type: LocalParameter

381943
units: 304591
value: 0.0
type: LocalParameter

312304
stoichiometry: 2.0
species: 378350
type: SpeciesReference

315728
stoichiometry: 1.0
species: 377969
type: SpeciesReference

321933
stoichiometry: 1.0
species: 378527
type: SpeciesReference

378939
product: 311953
notes: GENE_ASSOCIATION: (5832.1) SUBSYSTEM: Urea cycle/amino group metabolism
kinetic law: 311965
type: Reaction
reactant: 311929
reversible: false
reactant: 311917
fast: false
product: 311941
name: glutamate5-kinase(m)

383023
units: 304591
value: 0.0
type: LocalParameter

312776
stoichiometry: 1.0
species: 378035
type: SpeciesReference

313126
stoichiometry: 1.0
species: 377945
type: SpeciesReference

382539
units: 304591
value: 0.0
type: LocalParameter

304891
stoichiometry: 1.0
species: 378329
type: SpeciesReference

312909
stoichiometry: 1.0
species: 377754
type: SpeciesReference

383238
units: 304591
value: 0.0
type: LocalParameter

382644
units: 304591
value: 0.0
type: LocalParameter

382310
units: 304591
value: 1000.0
type: LocalParameter

382399
units: 304591
value: 0.0
type: LocalParameter

318108
stoichiometry: 1.0
species: 378167
type: SpeciesReference

378702
kinetic law: 307135
product: 307123
reactant: 307111
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: O2transport(diffusion)
type: Reaction

382284
units: 304591
value: 0.0
type: LocalParameter

322829
stoichiometry: 1.0
species: 377700
type: SpeciesReference

380565
units: 304591
value: 0.0
type: LocalParameter

326684
stoichiometry: 1.0
species: 378131
type: SpeciesReference

320811
stoichiometry: 1.0
species: 378179
type: SpeciesReference

324442
stoichiometry: 1.0
species: 377790
type: SpeciesReference

377549
constant: true
size: 1.0
spatial dimensions: 3.0
name: Mitochondrion
type: Compartment

383022
units: 304591
value: 0.0
type: LocalParameter

381395
units: 304591
value: -1000.0
type: LocalParameter

319448
stoichiometry: 1.0
species: 378278
type: SpeciesReference

306192
stoichiometry: 1.0
species: 378023
type: SpeciesReference

378663
name: purine-nucleosidephosphorylase(Deoxyguanosine)
product: 306372
kinetic law: 306384
reactant: 306336
fast: false
product: 306360
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism
type: Reaction
reversible: true
reactant: 306348

383237
units: 304591
value: 0.0
type: LocalParameter

382398
units: 304591
value: 0.0
type: LocalParameter

313198
stoichiometry: 1.0
species: 377948
type: SpeciesReference

313417
stoichiometry: 1.0
species: 378059
type: SpeciesReference

381941
units: 304591
value: 0.0
type: LocalParameter

306036
stoichiometry: 1.0
species: 377694
type: SpeciesReference

382287
units: 304591
value: 0.0
type: LocalParameter

381394
units: 304591
value: 0.0
type: LocalParameter

313875
stoichiometry: 1.0
species: 377769
type: SpeciesReference

380638
units: 304591
value: 1000.0
type: LocalParameter

382070
units: 304591
value: -1000.0
type: LocalParameter

381304
units: 304591
value: 0.0
type: LocalParameter

381620
units: 304591
value: 0.0
type: LocalParameter

380044
units: 304591
value: 1000.0
type: LocalParameter

316562
stoichiometry: 1.0
species: 378122
type: SpeciesReference

383026
units: 304591
value: 0.0
type: LocalParameter

382537
units: 304591
value: 0.0
type: LocalParameter

382312
units: 304591
value: 0.0
type: LocalParameter

382642
units: 304591
value: 0.0
type: LocalParameter

379614
kinetic law: 324526
reactant: 324514
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

321147
stoichiometry: 1.0
species: 378077
type: SpeciesReference

323692
stoichiometry: 1.0
species: 377787
type: SpeciesReference

380778
units: 304591
value: 1000.0
type: LocalParameter

314894
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382286
units: 304591
value: 0.0
type: LocalParameter

383024
units: 304591
value: 13.5135135135135
type: LocalParameter

380150
units: 304591
value: 0.0
type: LocalParameter

308245
stoichiometry: 2.0
species: 378059
type: SpeciesReference

309596
stoichiometry: 1.0
species: 377703
type: SpeciesReference

381305
units: 304591
value: -1000.0
type: LocalParameter

383025
units: 304591
value: 0.0
type: LocalParameter

377760
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Asparagine
type: Species

314139
stoichiometry: 1.0
species: 378398
type: SpeciesReference

383239
units: 304591
value: -1000.0
type: LocalParameter

380151
units: 304591
value: 0.0
type: LocalParameter

380041
units: 304591
value: 0.0
type: LocalParameter

325455
stoichiometry: 1.0
species: 378203
type: SpeciesReference

311469
stoichiometry: 1.0
species: 377895
type: SpeciesReference

381799
units: 304591
value: 1000.0
type: LocalParameter

380901
units: 304591
value: 0.0
type: LocalParameter

378705
type: Reaction
reactant: 307159
reversible: true
fast: false
kinetic law: 307196
name: citratetransport,mitochondrial
product: 307183
reactant: 307147
product: 307171
notes: GENE_ASSOCIATION: (6576.1) SUBSYSTEM: Transport, Mitochondrial

382140
units: 304591
value: -1000.0
type: LocalParameter

308861
stoichiometry: 1.0
species: 377769
type: SpeciesReference

377862
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: diacylglycerol (homo sapiens)
type: Species

380568
units: 304591
value: 1000.0
type: LocalParameter

383233
units: 304591
value: 0.0
type: LocalParameter

383090
units: 304591
value: 0.0
type: LocalParameter

382314
units: 304591
value: 0.0
type: LocalParameter

382427
units: 304591
value: -1000.0
type: LocalParameter

382640
units: 304591
value: 1000.0
type: LocalParameter

383234
units: 304591
value: 0.0
type: LocalParameter

378245
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Ammonium
type: Species

316236
stoichiometry: 1.0
species: 377933
type: SpeciesReference

379971
units: 304591
value: -1000.0
type: LocalParameter

381622
units: 304591
value: 0.0
type: LocalParameter

377763
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Aspartate
type: Species

378660
kinetic law: 306324
fast: false
reactant: 306276
reactant: 306288
product: 306312
type: Reaction
product: 306300
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism
reversible: true
name: purine-nucleosidephosphorylase(Deoxyadenosine)

315182
stoichiometry: 1.0
species: 377996
type: SpeciesReference

380635
units: 304591
value: -1000.0
type: LocalParameter

381946
units: 304591
value: 1000.0
type: LocalParameter

313283
stoichiometry: 1.0
species: 377865
type: SpeciesReference

380040
units: 304591
value: 0.0
type: LocalParameter

378515
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Tyrosine
type: Species

383091
units: 304591
value: -1000.0
type: LocalParameter

383232
units: 304591
value: 13.5135135135135
type: LocalParameter

322528
stoichiometry: 1.0
species: 378314
type: SpeciesReference

382280
units: 304591
value: -1000.0
type: LocalParameter

319230
stoichiometry: 1.0
species: 378056
type: SpeciesReference

379970
units: 304591
value: 0.0
type: LocalParameter

316984
stoichiometry: 1.0
species: 378077
type: SpeciesReference

326709
stoichiometry: 1.0
species: 377969
type: SpeciesReference

379611
kinetic law: 324502
reactant: 324490
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382315
units: 304591
value: 0.0
type: LocalParameter

322672
stoichiometry: 1.0
species: 378317
type: SpeciesReference

379491
kinetic law: 322407
product: 322395
reactant: 322383
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: Acetylcholintransport,nucleartrhoughpores
type: Reaction

379386
reactant: 320510
product: 320534
reversible: false
reactant: 320522
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
kinetic law: 320559
name: Rgroupartificialflux
product: 320546
fast: false
type: Reaction

315668
stoichiometry: 1.0
species: 377996
type: SpeciesReference

383021
units: 304591
value: 0.0
type: LocalParameter

380634
units: 304591
value: 0.0
type: LocalParameter

383092
units: 304591
value: 13.5135135135135
type: LocalParameter

321075
stoichiometry: 1.0
species: 378227
type: SpeciesReference

382142
units: 304591
value: 1000.0
type: LocalParameter

319604
stoichiometry: 1.0
species: 377936
type: SpeciesReference

323982
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381308
units: 304591
value: 1000.0
type: LocalParameter

379389
kinetic law: 320595
product: 320583
reactant: 320571
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: false
name: Rtotalflux
type: Reaction

383236
units: 304591
value: 0.0
type: LocalParameter

380154
units: 304591
value: 1000.0
type: LocalParameter

379590
kinetic law: 324334
reactant: 324322
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382429
units: 304591
value: 1000.0
type: LocalParameter

379494
kinetic law: 322444
product: 322431
reactant: 322419
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: Cholinetransport,nuclearthroughpores
type: Reaction

383020
units: 304591
value: 13.5135135135135
type: LocalParameter

381944
units: 304591
value: 0.0
type: LocalParameter

382282
units: 304591
value: 1000.0
type: LocalParameter

383093
units: 304591
value: 0.0
type: LocalParameter

378512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Tryptamine
type: Species

378248
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Ammonium
type: Species

310513
stoichiometry: 1.0
species: 378410
type: SpeciesReference

382317
units: 304591
value: 1000.0
type: LocalParameter

326371
stoichiometry: 1.0
species: 378107
type: SpeciesReference

383235
units: 304591
value: -1000.0
type: LocalParameter

381398
units: 304591
value: 1000.0
type: LocalParameter

381623
units: 304591
value: 0.0
type: LocalParameter

381415
units: 304591
value: -1000.0
type: LocalParameter

315074
stoichiometry: 1.0
species: 378497
type: SpeciesReference

378930
reversible: true
type: Reaction
name: D-Lactaldehyde:NAD+oxidoreductase(glutathione-formylating)
reactant: 311676
kinetic law: 311748
reactant: 311700
product: 311712
reactant: 311688
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
product: 311724
fast: false
product: 311736

316345
stoichiometry: 1.0
species: 377793
type: SpeciesReference

378864
reactant: 310139
kinetic law: 310176
reversible: true
reactant: 310151
product: 310163
notes: GENE_ASSOCIATION: SUBSYSTEM: Arginine and Proline Metabolism
reactant: 310126
type: Reaction
fast: false
name: L-1-Pyrroline-3-hydroxy-5-carboxylatespontaneousconversiontoL-4-Hydroxyglutamatesemialdehyde,mitochondrial

379383
kinetic law: 320498
product: 320486
reactant: 320473
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: false
name: Rtotalflux
type: Reaction

379503
kinetic law: 322552
product: 322540
reactant: 322528
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: phosphatidylinositol4-phosphatenucleartransport(diffusion)
type: Reaction

321366
stoichiometry: 1.0
species: 378428
type: SpeciesReference

382144
units: 304591
value: 0.0
type: LocalParameter

318084
stoichiometry: 1.0
species: 377844
type: SpeciesReference

307087
stoichiometry: 1.0
species: 378338
type: SpeciesReference

380484
units: 304591
value: 0.0
type: LocalParameter

383094
units: 304591
value: 0.0
type: LocalParameter

383176
units: 304591
value: 13.5135135135135
type: LocalParameter

305704
stoichiometry: 1.0
species: 377652
type: SpeciesReference

379593
kinetic law: 324358
reactant: 324346
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382319
units: 304591
value: 0.0
type: LocalParameter

382424
units: 304591
value: 0.0
type: LocalParameter

378137
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Inosine
type: Species

379974
units: 304591
value: 1000.0
type: LocalParameter

381723
units: 304591
value: 1000.0
type: LocalParameter

381794
units: 304591
value: 0.0
type: LocalParameter

383095
units: 304591
value: -1000.0
type: LocalParameter

383175
units: 304591
value: -1000.0
type: LocalParameter

380338
units: 304591
value: 1000.0
type: LocalParameter

383179
units: 304591
value: -1000.0
type: LocalParameter

382147
units: 304591
value: -1000.0
type: LocalParameter

381515
units: 304591
value: -1000.0
type: LocalParameter

382392
units: 304591
value: 0.0
type: LocalParameter

383231
units: 304591
value: -1000.0
type: LocalParameter

380998
units: 304591
value: 1000.0
type: LocalParameter

381797
units: 304591
value: 0.0
type: LocalParameter

304807
stoichiometry: 1.0
species: 378338
type: SpeciesReference

383178
units: 304591
value: 0.0
type: LocalParameter

306108
stoichiometry: 1.0
species: 377730
type: SpeciesReference

383096
units: 304591
value: 13.5135135135135
type: LocalParameter

378867
notes: GENE_ASSOCIATION: SUBSYSTEM: Arginine and Proline Metabolism
name: L-glutamate5-semialdehydedehydratase,reversible,mitochondrial
product: 310224
fast: false
reactant: 310188
reversible: true
kinetic law: 310236
product: 310200
product: 310212
type: Reaction

317697
stoichiometry: 1.0
species: 378488
type: SpeciesReference

315377
stoichiometry: 1.0
species: 378449
type: SpeciesReference

382649
units: 304591
value: 0.0
type: LocalParameter

319676
stoichiometry: 1.0
species: 378242
type: SpeciesReference

381514
units: 304591
value: 0.0
type: LocalParameter

379500
kinetic law: 322516
product: 322504
reactant: 322492
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: phosphatidylinositol4,5-bisphosphatenucleartransport(diffusion)
type: Reaction

315304
stoichiometry: 1.0
species: 377996
type: SpeciesReference

319712
stoichiometry: 1.0
species: 378227
type: SpeciesReference

382146
units: 304591
value: 0.0
type: LocalParameter

308461
stoichiometry: 1.0
species: 378221
type: SpeciesReference

382426
units: 304591
value: 0.0
type: LocalParameter

378017
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Reduced glutathione
type: Species

317721
stoichiometry: 1.0
species: 378485
type: SpeciesReference

379497
kinetic law: 322480
product: 322468
reactant: 322456
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: ribosetransportviadiffusion
type: Reaction

381418
units: 304591
value: 1000.0
type: LocalParameter

380485
units: 304591
value: 0.0
type: LocalParameter

381796
units: 304591
value: 0.0
type: LocalParameter

306252
stoichiometry: 1.0
species: 378416
type: SpeciesReference

383230
units: 304591
value: 0.0
type: LocalParameter

382391
units: 304591
value: 0.0
type: LocalParameter

378708
kinetic law: 307233
product: 307221
reactant: 307208
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: H2Otransport,nuclear
type: Reaction

322757
stoichiometry: 1.0
species: 378470
type: SpeciesReference

381948
units: 304591
value: 0.0
type: LocalParameter

305158
stoichiometry: 1.0
species: 377871
type: SpeciesReference

383177
units: 304591
value: 0.0
type: LocalParameter

381725
units: 304591
value: 0.0
type: LocalParameter

383097
units: 304591
value: 0.0
type: LocalParameter

381790
units: 304591
value: 0.0
type: LocalParameter

382149
units: 304591
value: 1000.0
type: LocalParameter

382535
units: 304591
value: 1000.0
type: LocalParameter

379596
kinetic law: 324382
reactant: 324370
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

381411
units: 304591
value: 0.0
type: LocalParameter

383028
units: 304591
value: 13.5135135135135
type: LocalParameter

312413
stoichiometry: 1.0
species: 378212
type: SpeciesReference

312993
stoichiometry: 1.0
species: 378227
type: SpeciesReference

383098
units: 304591
value: 0.0
type: LocalParameter

308137
stoichiometry: 1.0
species: 378455
type: SpeciesReference

380415
units: 304591
value: -1000.0
type: LocalParameter

380335
units: 304591
value: -1000.0
type: LocalParameter

382394
units: 304591
value: 1000.0
type: LocalParameter

380488
units: 304591
value: 1000.0
type: LocalParameter

378669
reactant: 306469
reversible: true
kinetic law: 306505
product: 306493
product: 306481
reactant: 306457
type: Reaction
fast: false
name: purine-nucleosidephosphorylase(Deoxyinosine)
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism

307763
stoichiometry: 1.0
species: 377673
type: SpeciesReference

313041
stoichiometry: 1.0
species: 378278
type: SpeciesReference

382289
units: 304591
value: 1000.0
type: LocalParameter

382534
units: 304591
value: 0.0
type: LocalParameter

382647
units: 304591
value: 1000.0
type: LocalParameter

382420
units: 304591
value: -1000.0
type: LocalParameter

383027
units: 304591
value: 0.0
type: LocalParameter

320883
stoichiometry: 1.0
species: 378365
type: SpeciesReference

381391
units: 304591
value: 0.0
type: LocalParameter

378936
reactant: 311832
type: Reaction
reactant: 311856
product: 311892
name: glutamate-5-semialdehydedehydrogenase(m)
kinetic law: 311904
reversible: false
fast: false
product: 311868
product: 311880
notes: GENE_ASSOCIATION: (5832.1) SUBSYSTEM: Urea cycle/amino group metabolism
reactant: 311844

381727
units: 304591
value: 0.0
type: LocalParameter

383099
units: 304591
value: -1000.0
type: LocalParameter

313525
stoichiometry: 1.0
species: 378056
type: SpeciesReference

380561
units: 304591
value: 0.0
type: LocalParameter

380334
units: 304591
value: 0.0
type: LocalParameter

312158
stoichiometry: 1.0
species: 378392
type: SpeciesReference

320292
stoichiometry: 1.0
species: 378152
type: SpeciesReference

379940
units: 304591
value: 0.0
type: LocalParameter

378666
reactant: 306408
reversible: true
fast: false
notes: GENE_ASSOCIATION: (4860.1) SUBSYSTEM: Purine Catabolism
product: 306420
reactant: 306396
kinetic law: 306444
name: purine-nucleosidephosphorylase(Inosine)
type: Reaction
product: 306432

379977
units: 304591
value: 0.0
type: LocalParameter

319122
stoichiometry: 1.0
species: 377646
type: SpeciesReference

381792
units: 304591
value: 1000.0
type: LocalParameter

326009
stoichiometry: 1.0
species: 378191
type: SpeciesReference

321872
stoichiometry: 1.0
species: 378392
type: SpeciesReference

381511
units: 304591
value: 0.0
type: LocalParameter

316453
stoichiometry: 3.0
species: 378209
type: SpeciesReference

378933
kinetic law: 311820
name: D-Lactaldehyde:NADP+1-oxidoreductase
reversible: false
reactant: 311772
reactant: 311760
fast: false
product: 311796
reactant: 311784
type: Reaction
notes: GENE_ASSOCIATION: (10327.1) or (8574.1) or (10327.2) or (231.1) SUBSYSTEM: Pyruvate Metabolism
product: 311808

381728
units: 304591
value: -1000.0
type: LocalParameter

323584
stoichiometry: 1.0
species: 377790
type: SpeciesReference

311688
stoichiometry: 1.0
species: 378152
type: SpeciesReference

379506
kinetic law: 322588
product: 322576
reactant: 322564
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
type: Reaction

318941
stoichiometry: 1.0
species: 378206
type: SpeciesReference

382396
units: 304591
value: 0.0
type: LocalParameter

382645
units: 304591
value: -1000.0
type: LocalParameter

379599
kinetic law: 324406
reactant: 324394
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382422
units: 304591
value: 1000.0
type: LocalParameter

318216
stoichiometry: 1.0
species: 377688
type: SpeciesReference

379941
units: 304591
value: 0.0
type: LocalParameter

381414
units: 304591
value: 0.0
type: LocalParameter

383029
units: 304591
value: 0.0
type: LocalParameter

381301
units: 304591
value: 0.0
type: LocalParameter

379380
kinetic law: 320461
product: 320449
reactant: 320437
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: false
name: Rgroupartificialflux
type: Reaction

378861
fast: false
product: 310090
reactant: 310042
notes: GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Arginine and Proline Metabolism
reversible: false
name: L-1-pyrroline-3-hydroxy-5-carboxylatedehydrogenase
product: 310102
product: 310078
kinetic law: 310114
reactant: 310054
reactant: 310066
type: Reaction

308679
stoichiometry: 1.0
species: 378533
type: SpeciesReference

380418
units: 304591
value: 1000.0
type: LocalParameter

311311
stoichiometry: 1.0
species: 377715
type: SpeciesReference

313767
stoichiometry: 1.0
species: 378308
type: SpeciesReference

325335
stoichiometry: 1.0
species: 378113
type: SpeciesReference

314702
stoichiometry: 1.0
species: 377595
type: SpeciesReference

318724
stoichiometry: 1.0
species: 377811
type: SpeciesReference

312497
stoichiometry: 1.0
species: 377817
type: SpeciesReference

317237
stoichiometry: 1.0
species: 378527
type: SpeciesReference

322961
stoichiometry: 1.0
species: 378152
type: SpeciesReference

382976
units: 304591
value: 13.5135135135135
type: LocalParameter

316284
stoichiometry: 1.0
species: 378455
type: SpeciesReference

379155
notes: GENE_ASSOCIATION: (1103.4) or (1103.1) or (1103.3) or (1103.2) SUBSYSTEM: Glycerophospholipid Metabolism
product: 316429
product: 316417
kinetic law: 316441
name: CholineO-acetyltransferase
fast: false
reactant: 316405
reactant: 316393
type: Reaction
reversible: true

381278
units: 304591
value: 1000.0
type: LocalParameter

379758
kinetic law: 325684
reactant: 325672
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: nC20:4exchange
type: Reaction

379947
units: 304591
value: 0.0
type: LocalParameter

380411
units: 304591
value: 0.0
type: LocalParameter

305097
stoichiometry: 1.0
species: 377616
type: SpeciesReference

305776
stoichiometry: 1.0
species: 377700
type: SpeciesReference

378140
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: potassium
type: Species

320340
stoichiometry: 1.0
species: 378218
type: SpeciesReference

315596
stoichiometry: 1.0
species: 377966
type: SpeciesReference

378020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Reduced glutathione
type: Species

382977
units: 304591
value: 0.0
type: LocalParameter

310961
stoichiometry: 1.96
species: 378065
type: SpeciesReference

379509
reversible: false
product: 322636
name: phosphatidylinositol-4,5-bisphosphate5-phosphatase,nuclear
reactant: 322600
reactant: 322612
type: Reaction
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism
kinetic law: 322648
product: 322624

380414
units: 304591
value: 0.0
type: LocalParameter

323356
stoichiometry: 1.0
species: 378047
type: SpeciesReference

309608
stoichiometry: 1.0
species: 377769
type: SpeciesReference

317927
stoichiometry: 2.0
species: 378095
type: SpeciesReference

311892
stoichiometry: 1.0
species: 378344
type: SpeciesReference

306928
stoichiometry: 1.0
species: 378170
type: SpeciesReference

377616
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 3-Phospho-D-glycerate
type: Species

322176
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380991
units: 304591
value: 0.0
type: LocalParameter

316115
stoichiometry: 1.0
species: 378140
type: SpeciesReference

379266
product: 318337
reactant: 318300
product: 318324
kinetic law: 318349
reactant: 318312
fast: false
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
reversible: true
type: Reaction
name: fattyacidelectroneutraltransport

382761
units: 304591
value: 0.0
type: LocalParameter

378143
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: potassium
type: Species

382978
units: 304591
value: 0.0
type: LocalParameter

377571
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 13-cis-oxo-retinoic acid
type: Species

324923
stoichiometry: 1.0
species: 377724
type: SpeciesReference

304759
stoichiometry: 1.0
species: 378338
type: SpeciesReference

379041
product: 314043
reactant: 314019
reactant: 314031
reversible: false
type: Reaction
kinetic law: 314067
fast: false
product: 314055
name: phosphatidylinositol-4-phosphate4-phosphatase
notes: GENE_ASSOCIATION: SUBSYSTEM: Inositol Phosphate Metabolism

320919
stoichiometry: 1.0
species: 378371
type: SpeciesReference

310369
stoichiometry: 1.0
species: 377700
type: SpeciesReference

318651
stoichiometry: 2.0
species: 377811
type: SpeciesReference

383170
units: 304591
value: 0.0
type: LocalParameter

321595
stoichiometry: 1.0
species: 378368
type: SpeciesReference

319893
stoichiometry: 1.0
species: 378542
type: SpeciesReference

379944
units: 304591
value: 1000.0
type: LocalParameter

379755
kinetic law: 325660
reactant: 325648
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Calciumexchange
type: Reaction

315523
stoichiometry: 1.0
species: 377721
type: SpeciesReference

304963
stoichiometry: 1.0
species: 377700
type: SpeciesReference

377978
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Glutamate
type: Species

317465
stoichiometry: 1.0
species: 378128
type: SpeciesReference

382979
units: 304591
value: 0.0
type: LocalParameter

379152
kinetic law: 316381
notes: GENE_ASSOCIATION: (1103.4) or (1103.2) or (1103.3) or (1103.1) SUBSYSTEM: Glycerophospholipid Metabolism
type: Reaction
fast: false
name: CholineO-acetyltransferase
product: 316357
product: 316369
reactant: 316333
reversible: true
reactant: 316345

322226
stoichiometry: 2.0
species: 378077
type: SpeciesReference

313983
stoichiometry: 1.0
species: 378059
type: SpeciesReference

323010
stoichiometry: 1.0
species: 378059
type: SpeciesReference

383171
units: 304591
value: -1000.0
type: LocalParameter

380848
units: 304591
value: 1000.0
type: LocalParameter

310163
stoichiometry: 1.0
species: 377625
type: SpeciesReference

378023
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: GTP
type: Species

313308
stoichiometry: 1.0
species: 377880
type: SpeciesReference

382876
units: 304591
value: 0.0
type: LocalParameter

382972
units: 304591
value: 13.5135135135135
type: LocalParameter

382763
units: 304591
value: 0.0
type: LocalParameter

309488
stoichiometry: 1.0
species: 378047
type: SpeciesReference

383172
units: 304591
value: 13.5135135135135
type: LocalParameter

312631
stoichiometry: 1.0
species: 378077
type: SpeciesReference

314786
stoichiometry: 1.0
species: 378161
type: SpeciesReference

377975
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Glutamate 5-semialdehyde
type: Species

379044
kinetic law: 314103
product: 314091
reactant: 314079
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: pyridoxaltransportviadiffusion
type: Reaction

380491
units: 304591
value: 0.0
type: LocalParameter

382973
units: 304591
value: 0.0
type: LocalParameter

312849
stoichiometry: 1.0
species: 377874
type: SpeciesReference

377610
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glycerate 2-phosphate
type: Species

382875
units: 304591
value: 0.0
type: LocalParameter

306312
stoichiometry: 1.0
species: 377688
type: SpeciesReference

383173
units: 304591
value: 0.0
type: LocalParameter

380995
units: 304591
value: 0.0
type: LocalParameter

324043
stoichiometry: 1.0
species: 378143
type: SpeciesReference

381721
units: 304591
value: -1000.0
type: LocalParameter

381275
units: 304591
value: 0.0
type: LocalParameter

377972
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Glutamate 5-phosphate
type: Species

314351
stoichiometry: 1.0
species: 377769
type: SpeciesReference

381518
units: 304591
value: 1000.0
type: LocalParameter

382974
units: 304591
value: 0.0
type: LocalParameter

326226
stoichiometry: 1.0
species: 378335
type: SpeciesReference

318434
stoichiometry: 1.0
species: 378260
type: SpeciesReference

382878
units: 304591
value: 13.5135135135135
type: LocalParameter

323813
stoichiometry: 1.0
species: 377727
type: SpeciesReference

305449
stoichiometry: 1.0
species: 377923
type: SpeciesReference

310852
stoichiometry: 2.0
species: 378083
type: SpeciesReference

377613
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 3-Dehydro-L-gulonate
type: Species

310224
stoichiometry: 1.0
species: 378083
type: SpeciesReference

380994
units: 304591
value: 0.0
type: LocalParameter

383174
units: 304591
value: 0.0
type: LocalParameter

321728
stoichiometry: 1.0
species: 378236
type: SpeciesReference

319340
stoichiometry: 2.0
species: 378140
type: SpeciesReference

381720
units: 304591
value: 0.0
type: LocalParameter

381161
units: 304591
value: 0.0
type: LocalParameter

381274
units: 304591
value: 0.0
type: LocalParameter

378449
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Serine
type: Species

378146
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Lactate
type: Species

378026
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: GTP
type: Species

377574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 13-cis-retinoate
type: Species

379269
reactant: 318361
reactant: 318374
product: 318386
reversible: true
kinetic law: 318410
type: Reaction
name: fattyacidelectroneutraltransport
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
fast: false
product: 318398

382975
units: 304591
value: 0.0
type: LocalParameter

382764
units: 304591
value: -1000.0
type: LocalParameter

314423
stoichiometry: 1.0
species: 378071
type: SpeciesReference

378380
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Proline
type: Species

377577
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 13-cis-retinoate
type: Species

377766
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Aspartate
type: Species

379047
name: pyridoxaldehydrogenase
reactant: 314127
reactant: 314139
notes: GENE_ASSOCIATION: (316.1) SUBSYSTEM: Vitamin B6 Metabolism
fast: false
type: Reaction
reactant: 314115
kinetic law: 314175
product: 314163
reversible: false
product: 314151

325816
stoichiometry: 1.0
species: 377664
type: SpeciesReference

378383
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Proline
type: Species

381625
units: 304591
value: 1000.0
type: LocalParameter

378597
kinetic law: 305085
product: 305073
reactant: 305061
notes: GENE_ASSOCIATION: (5223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: phosphoglyceratemutase
type: Reaction

378254
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Ammonium
type: Species

379260
kinetic law: 318228
product: 318216
reactant: 318204
notes: GENE_ASSOCIATION: (3177.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: adeninereversibletransport,cytosol
type: Reaction

377865
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyguanosine
type: Species

380631
units: 304591
value: 0.0
type: LocalParameter

381164
units: 304591
value: 0.0
type: LocalParameter

380844
units: 304591
value: 0.0
type: LocalParameter

325115
stoichiometry: 1.0
species: 377923
type: SpeciesReference

381876
units: 304591
value: 1000.0
type: LocalParameter

317032
stoichiometry: 1.0
species: 377814
type: SpeciesReference

308029
stoichiometry: 1.0
species: 377736
type: SpeciesReference

382766
units: 304591
value: 1000.0
type: LocalParameter

380144
units: 304591
value: 1000.0
type: LocalParameter

382871
units: 304591
value: 13.5135135135135
type: LocalParameter

378446
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Sorbitol
type: Species

307486
stoichiometry: 1.0
species: 378218
type: SpeciesReference

310586
stoichiometry: 1.0
species: 378182
type: SpeciesReference

306747
stoichiometry: 1.0
species: 378344
type: SpeciesReference

326467
stoichiometry: 1.0
species: 377760
type: SpeciesReference

380147
units: 304591
value: 0.0
type: LocalParameter

305668
stoichiometry: 1.0
species: 377661
type: SpeciesReference

323704
stoichiometry: 1.0
species: 378059
type: SpeciesReference

310743
stoichiometry: 1.0
species: 378410
type: SpeciesReference

323608
stoichiometry: 1.0
species: 377769
type: SpeciesReference

382970
units: 304591
value: 0.0
type: LocalParameter

381627
units: 304591
value: 0.0
type: LocalParameter

378443
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sedoheptulose 7-phosphate
type: Species

382200
units: 304591
value: 0.0
type: LocalParameter

381271
units: 304591
value: 0.0
type: LocalParameter

306469
stoichiometry: 1.0
species: 378338
type: SpeciesReference

377769
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: ATP
type: Species

381878
units: 304591
value: 0.0
type: LocalParameter

382873
units: 304591
value: 0.0
type: LocalParameter

382768
units: 304591
value: 0.0
type: LocalParameter

382971
units: 304591
value: 0.0
type: LocalParameter

318324
stoichiometry: 1.0
species: 377847
type: SpeciesReference

382079
units: 304591
value: 1000.0
type: LocalParameter

378518
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Tyrosine
type: Species

380845
units: 304591
value: 0.0
type: LocalParameter

381165
units: 304591
value: -1000.0
type: LocalParameter

380771
units: 304591
value: 0.0
type: LocalParameter

320413
stoichiometry: 1.0
species: 378218
type: SpeciesReference

323094
stoichiometry: 1.0
species: 378098
type: SpeciesReference

306675
stoichiometry: 1.0
species: 378119
type: SpeciesReference

379752
kinetic law: 325636
reactant: 325624
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Chlorideexchange
type: Reaction

383229
units: 304591
value: 0.0
type: LocalParameter

379698
kinetic law: 325200
reactant: 325188
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

381629
units: 304591
value: 0.0
type: LocalParameter

315886
stoichiometry: 1.0
species: 377634
type: SpeciesReference

380037
units: 304591
value: 0.0
type: LocalParameter

316175
stoichiometry: 3.0
species: 378206
type: SpeciesReference

305365
stoichiometry: 1.0
species: 378443
type: SpeciesReference

310006
stoichiometry: 1.0
species: 378083
type: SpeciesReference

308715
stoichiometry: 1.0
species: 378278
type: SpeciesReference

325672
stoichiometry: 1.0
species: 377742
type: SpeciesReference

382077
units: 304591
value: -1000.0
type: LocalParameter

316767
stoichiometry: 2.0
species: 378206
type: SpeciesReference

379263
product: 318264
product: 318276
notes: GENE_ASSOCIATION: (11001.1) SUBSYSTEM: Transport, Extracellular
name: fattyacidelectroneutraltransport
fast: false
type: Reaction
reversible: true
reactant: 318240
kinetic law: 318288
reactant: 318252

378386
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Prostaglandin D2
type: Species

381168
units: 304591
value: 1000.0
type: LocalParameter

322600
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species: 378068
type: SpeciesReference

305559
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species: 378404
type: SpeciesReference

317129
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species: 378095
type: SpeciesReference

316007
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species: 378140
type: SpeciesReference

377545
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size: 1.0
spatial dimensions: 3.0
name: Cytoplasm
type: Compartment

379158
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product: 316477
reactant: 316453
product: 316489
fast: false
name: phosphatetransportin/outviathreeNa+symporter(irreversible)
notes: GENE_ASSOCIATION: (10786.1) SUBSYSTEM: Transport, Extracellular
type: Reaction
kinetic law: 316501
reactant: 316465

307618
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species: 378266
type: SpeciesReference

377619
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4-Aminobutanoate
type: Species

307208
stoichiometry: 1.0
species: 378068
type: SpeciesReference

324116
stoichiometry: 1.0
species: 378335
type: SpeciesReference

381871
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value: 0.0
type: LocalParameter

382076
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value: 0.0
type: LocalParameter

311977
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species: 378077
type: SpeciesReference

377868
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Deoxyguanosine
type: Species

308570
stoichiometry: 1.0
species: 378380
type: SpeciesReference

382321
units: 304591
value: 0.0
type: LocalParameter

378389
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Prostaglandin H2
type: Species

317575
stoichiometry: 2.0
species: 378209
type: SpeciesReference

305800
stoichiometry: 1.0
species: 378419
type: SpeciesReference

315946
stoichiometry: 1.0
species: 377957
type: SpeciesReference

377546
constant: true
size: 1.0
spatial dimensions: 3.0
name: Extracellular
type: Compartment

319821
stoichiometry: 1.0
species: 377999
type: SpeciesReference

319785
stoichiometry: 1.0
species: 378089
type: SpeciesReference

322067
stoichiometry: 1.0
species: 377670
type: SpeciesReference

306819
stoichiometry: 1.0
species: 378218
type: SpeciesReference

380774
units: 304591
value: 0.0
type: LocalParameter

381874
units: 304591
value: -1000.0
type: LocalParameter

317818
stoichiometry: 1.0
species: 378206
type: SpeciesReference

326154
stoichiometry: 1.0
species: 378503
type: SpeciesReference

378440
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Ribulose 5-phosphate
type: Species

378251
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ammonium
type: Species

320775
stoichiometry: 1.0
species: 378404
type: SpeciesReference

322116
stoichiometry: 1.0
species: 378299
type: SpeciesReference

380775
units: 304591
value: -1000.0
type: LocalParameter

380841
units: 304591
value: 0.0
type: LocalParameter

314810
stoichiometry: 1.0
species: 378158
type: SpeciesReference

323464
stoichiometry: 1.0
species: 378563
type: SpeciesReference

316827
stoichiometry: 1.0
species: 378206
type: SpeciesReference

382074
units: 304591
value: 0.0
type: LocalParameter

381873
units: 304591
value: 0.0
type: LocalParameter

378987
kinetic law: 312933
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
product: 312909
reactant: 312897
product: 312921
reversible: false
type: Reaction
fast: false
reactant: 312885

382810
units: 304591
value: 0.0
type: LocalParameter

379353
kinetic law: 319881
product: 319869
product: 319857
reactant: 319845
notes: GENE_ASSOCIATION: SUBSYSTEM: Pyruvate Metabolism
fast: false
reversible: false
name: methyglyoxylatesynthase2(fromg3p)
type: Reaction

315255
stoichiometry: 1.0
species: 378455
type: SpeciesReference

317963
stoichiometry: 1.0
species: 377742
type: SpeciesReference

310526
stoichiometry: 4.0
species: 378077
type: SpeciesReference

379981
units: 304591
value: -1000.0
type: LocalParameter

323921
stoichiometry: 1.0
species: 377969
type: SpeciesReference

380365
units: 304591
value: 0.0
type: LocalParameter

382130
units: 304591
value: 0.0
type: LocalParameter

381845
units: 304591
value: 0.0
type: LocalParameter

380051
units: 304591
value: 0.0
type: LocalParameter

383033
units: 304591
value: 0.0
type: LocalParameter

321087
stoichiometry: 1.0
species: 378425
type: SpeciesReference

325961
stoichiometry: 1.0
species: 377859
type: SpeciesReference

381957
units: 304591
value: 0.0
type: LocalParameter

324610
stoichiometry: 1.0
species: 378332
type: SpeciesReference

379980
units: 304591
value: 0.0
type: LocalParameter

318168
stoichiometry: 1.0
species: 378146
type: SpeciesReference

320522
stoichiometry: 1.0
species: 378098
type: SpeciesReference

378524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Urate
type: Species

382025
units: 304591
value: 0.0
type: LocalParameter

310429
stoichiometry: 1.0
species: 378215
type: SpeciesReference

382305
units: 304591
value: 0.0
type: LocalParameter

379422
kinetic law: 321317
product: 321305
reactant: 321293
reactant: 321281
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: false
name: 4-oxo-retinoicacidformation(oxidation)
type: Reaction

382673
units: 304591
value: 0.0
type: LocalParameter

380364
units: 304591
value: 0.0
type: LocalParameter

379290
reactant: 318775
reversible: true
reactant: 318762
name: K+-Cl-cotransport
notes: GENE_ASSOCIATION: (10723.1) SUBSYSTEM: Transport, Extracellular
product: 318788
kinetic law: 318814
fast: false
product: 318801
type: Reaction

382672
units: 304591
value: 0.0
type: LocalParameter

383032
units: 304591
value: 13.5135135135135
type: LocalParameter

306228
stoichiometry: 1.0
species: 378338
type: SpeciesReference

381361
units: 304591
value: 0.0
type: LocalParameter

309632
stoichiometry: 2.0
species: 378056
type: SpeciesReference

378906
kinetic law: 311142
product: 311130
reactant: 311118
reactant: 311106
notes: GENE_ASSOCIATION: SUBSYSTEM: Miscellaneous
fast: false
reversible: true
name: carboxylicaciddissociation
type: Reaction

381846
units: 304591
value: -1000.0
type: LocalParameter

380050
units: 304591
value: 0.0
type: LocalParameter

306966
stoichiometry: 1.0
species: 377823
type: SpeciesReference

319532
stoichiometry: 1.0
species: 377700
type: SpeciesReference

377751
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Arginine
type: Species

381365
units: 304591
value: 0.0
type: LocalParameter

315195
stoichiometry: 1.0
species: 378455
type: SpeciesReference

321643
stoichiometry: 1.0
species: 378224
type: SpeciesReference

378257
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinate D-ribonucleotide
type: Species

381658
units: 304591
value: 0.0
type: LocalParameter

382023
units: 304591
value: 1000.0
type: LocalParameter

381843
units: 304591
value: 0.0
type: LocalParameter

381095
units: 304591
value: -1000.0
type: LocalParameter

324322
stoichiometry: 1.0
species: 378386
type: SpeciesReference

383031
units: 304591
value: 0.0
type: LocalParameter

325140
stoichiometry: 1.0
species: 378140
type: SpeciesReference

381364
units: 304591
value: 0.0
type: LocalParameter

381657
units: 304591
value: 0.0
type: LocalParameter

378984
reversible: false
reactant: 312837
kinetic law: 312873
product: 312861
reactant: 312813
product: 312849
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
name: ascorbicacidoxidase
reactant: 312825
type: Reaction

379350
kinetic law: 319833
product: 319821
reactant: 319809
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: glycinepassivetransporttoperoxisome
type: Reaction

382675
units: 304591
value: 1000.0
type: LocalParameter

379647
kinetic law: 324791
reactant: 324779
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

383269
units: 304591
value: 0.0
type: LocalParameter

382303
units: 304591
value: 1000.0
type: LocalParameter

380361
units: 304591
value: 0.0
type: LocalParameter

322660
stoichiometry: 1.0
species: 378068
type: SpeciesReference

378527
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Urate
type: Species

381094
units: 304591
value: 0.0
type: LocalParameter

381958
units: 304591
value: 0.0
type: LocalParameter

311154
stoichiometry: 3.0
species: 378209
type: SpeciesReference

383030
units: 304591
value: 0.0
type: LocalParameter

313271
stoichiometry: 1.0
species: 377868
type: SpeciesReference

382300
units: 304591
value: 0.0
type: LocalParameter

379425
kinetic law: 321354
product: 321341
reactant: 321329
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 4-oxo-retinoicacidtransport,Nuclear
type: Reaction

319267
stoichiometry: 1.0
species: 377769
type: SpeciesReference

378521
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Urate
type: Species

319328
stoichiometry: 1.0
species: 378077
type: SpeciesReference

383038
units: 304591
value: 0.0
type: LocalParameter

378870
name: prolineoxidase(NAD),mitochondrial
fast: false
type: Reaction
product: 310296
reversible: false
product: 310284
product: 310272
notes: GENE_ASSOCIATION: (5625.1) SUBSYSTEM: Arginine and Proline Metabolism
reactant: 310248
reactant: 310260
kinetic law: 310308

314237
stoichiometry: 1.0
species: 377700
type: SpeciesReference

381421
units: 304591
value: 0.0
type: LocalParameter

325286
stoichiometry: 1.0
species: 378575
type: SpeciesReference

319062
stoichiometry: 1.0
species: 378038
type: SpeciesReference

381953
units: 304591
value: 1000.0
type: LocalParameter

380578
units: 304591
value: 1000.0
type: LocalParameter

306000
stoichiometry: 1.0
species: 377978
type: SpeciesReference

308533
stoichiometry: 1.0
species: 377835
type: SpeciesReference

382251
units: 304591
value: 0.0
type: LocalParameter

382301
units: 304591
value: 0.0
type: LocalParameter

382677
units: 304591
value: 0.0
type: LocalParameter

379356
kinetic law: 319917
product: 319905
reactant: 319893
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: xanthinediffusioninperoxisome
type: Reaction

314127
stoichiometry: 1.0
species: 378266
type: SpeciesReference

318917
stoichiometry: 1.0
species: 378248
type: SpeciesReference

383037
units: 304591
value: 0.0
type: LocalParameter

381655
units: 304591
value: 0.0
type: LocalParameter

321752
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380054
units: 304591
value: 1000.0
type: LocalParameter

311432
stoichiometry: 1.0
species: 378239
type: SpeciesReference

309150
stoichiometry: 1.0
species: 378071
type: SpeciesReference

380601
units: 304591
value: 0.0
type: LocalParameter

309842
stoichiometry: 1.0
species: 378227
type: SpeciesReference

380368
units: 304591
value: 1000.0
type: LocalParameter

380684
units: 304591
value: 0.0
type: LocalParameter

305583
stoichiometry: 1.0
species: 377661
type: SpeciesReference

382028
units: 304591
value: -1000.0
type: LocalParameter

379821
kinetic law: 326190
reactant: 326178
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Pyruvateexchange
type: Reaction

382738
units: 304591
value: 1000.0
type: LocalParameter

381148
units: 304591
value: 1000.0
type: LocalParameter

314918
stoichiometry: 1.0
species: 378206
type: SpeciesReference

379200
reversible: true
notes: GENE_ASSOCIATION: (8671.1) SUBSYSTEM: Transport, Extracellular
fast: false
name: bicarbonatetransport(Na/HCO31:3cotransport)
type: Reaction
product: 317153
reactant: 317129
product: 317165
kinetic law: 317177
reactant: 317141

383149
units: 304591
value: 0.0
type: LocalParameter

383036
units: 304591
value: 13.5135135135135
type: LocalParameter

378981
reactant: 312752
fast: false
product: 312776
kinetic law: 312801
reversible: true
type: Reaction
product: 312788
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
reactant: 312764
name: gluconolactonase,endoplasmicreticulum

380604
units: 304591
value: 0.0
type: LocalParameter

378903
product: 311069
reversible: false
product: 311081
reactant: 311057
notes: GENE_ASSOCIATION: (81537.1) SUBSYSTEM: Sphingolipid Metabolism
reactant: 311045
type: Reaction
fast: false
kinetic law: 311094
name: sphingoidbase-phosphatephosphatase(sphinganine1-phosphatase),endoplasmicreticulum

381955
units: 304591
value: 0.0
type: LocalParameter

315716
stoichiometry: 1.0
species: 378503
type: SpeciesReference

383035
units: 304591
value: 0.0
type: LocalParameter

312788
stoichiometry: 1.0
species: 378071
type: SpeciesReference

313186
stoichiometry: 1.0
species: 378086
type: SpeciesReference

382679
units: 304591
value: 0.0
type: LocalParameter

382027
units: 304591
value: 0.0
type: LocalParameter

380681
units: 304591
value: 0.0
type: LocalParameter

305863
stoichiometry: 1.0
species: 377607
type: SpeciesReference

380057
units: 304591
value: 0.0
type: LocalParameter

383148
units: 304591
value: 0.0
type: LocalParameter

381653
units: 304591
value: 1000.0
type: LocalParameter

311299
stoichiometry: 1.0
species: 378215
type: SpeciesReference

311544
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381848
units: 304591
value: 1000.0
type: LocalParameter

383034
units: 304591
value: 0.0
type: LocalParameter

313404
stoichiometry: 1.0
species: 377987
type: SpeciesReference

381098
units: 304591
value: 1000.0
type: LocalParameter

383263
units: 304591
value: -1000.0
type: LocalParameter

380574
units: 304591
value: 0.0
type: LocalParameter

311081
stoichiometry: 1.0
species: 378470
type: SpeciesReference

380478
units: 304591
value: 1000.0
type: LocalParameter

313344
stoichiometry: 1.0
species: 377733
type: SpeciesReference

311652
stoichiometry: 1.0
species: 378236
type: SpeciesReference

313754
stoichiometry: 1.0
species: 378059
type: SpeciesReference

324586
stoichiometry: 1.0
species: 378377
type: SpeciesReference

320955
stoichiometry: 1.0
species: 378371
type: SpeciesReference

381581
units: 304591
value: 0.0
type: LocalParameter

381425
units: 304591
value: -1000.0
type: LocalParameter

321860
stoichiometry: 1.0
species: 378233
type: SpeciesReference

377640
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R group 1 Coenzyme A homo sapiens
type: Species

383147
units: 304591
value: -1000.0
type: LocalParameter

379074
kinetic law: 314714
product: 314702
reactant: 314690
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: false
type: Reaction

382256
units: 304591
value: 0.0
type: LocalParameter

378630
reactant: 305680
reversible: false
notes: GENE_ASSOCIATION: (223.1) or (224.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
kinetic law: 305740
fast: false
product: 305704
name: aldehydedehydrogenase(acetaldehyde,NADP)
product: 305716
reactant: 305668
reactant: 305692
product: 305728
type: Reaction

382139
units: 304591
value: 0.0
type: LocalParameter

382457
units: 304591
value: 1000.0
type: LocalParameter

380688
units: 304591
value: 1000.0
type: LocalParameter

309994
stoichiometry: 1.0
species: 377984
type: SpeciesReference

383262
units: 304591
value: 0.0
type: LocalParameter

382254
units: 304591
value: 1000.0
type: LocalParameter

380575
units: 304591
value: -1000.0
type: LocalParameter

383145
units: 304591
value: 0.0
type: LocalParameter

311323
stoichiometry: 1.0
species: 378083
type: SpeciesReference

380605
units: 304591
value: -1000.0
type: LocalParameter

381582
units: 304591
value: 0.0
type: LocalParameter

381651
units: 304591
value: 0.0
type: LocalParameter

383146
units: 304591
value: 0.0
type: LocalParameter

378873
product: 310369
product: 310357
name: formate-tetrahydrofolateligase
fast: false
product: 310381
reactant: 310344
reactant: 310332
reversible: true
notes: GENE_ASSOCIATION: (4522.1) SUBSYSTEM: Folate Metabolism
reactant: 310320
type: Reaction
kinetic law: 310393

377914
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose 1,6-bisphosphate
type: Species

379587
kinetic law: 324310
reactant: 324298
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

378107
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Histidine
type: Species

383261
units: 304591
value: 0.0
type: LocalParameter

379428
kinetic law: 321390
product: 321378
reactant: 321366
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: retinoicacidtransport
type: Reaction

380685
units: 304591
value: -1000.0
type: LocalParameter

308101
stoichiometry: 1.0
species: 377703
type: SpeciesReference

383144
units: 304591
value: 0.0
type: LocalParameter

312897
stoichiometry: 2.0
species: 378017
type: SpeciesReference

380608
units: 304591
value: 1000.0
type: LocalParameter

379584
kinetic law: 324286
reactant: 324273
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

381650
units: 304591
value: 0.0
type: LocalParameter

379930
units: 304591
value: 0.0
type: LocalParameter

313078
stoichiometry: 1.0
species: 378254
type: SpeciesReference

380571
units: 304591
value: 0.0
type: LocalParameter

314019
stoichiometry: 1.0
species: 378059
type: SpeciesReference

378104
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Histidine
type: Species

382137
units: 304591
value: 0.0
type: LocalParameter

382969
units: 304591
value: 0.0
type: LocalParameter

382455
units: 304591
value: -1000.0
type: LocalParameter

382252
units: 304591
value: 0.0
type: LocalParameter

383260
units: 304591
value: 13.5135135135135
type: LocalParameter

325212
stoichiometry: 1.0
species: 378206
type: SpeciesReference

380475
units: 304591
value: 0.0
type: LocalParameter

378900
kinetic law: 311033
product: 311021
reactant: 311009
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: acetaldehydemitochondrialdiffusion
type: Reaction

309902
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381739
units: 304591
value: 0.0
type: LocalParameter

383143
units: 304591
value: -1000.0
type: LocalParameter

383039
units: 304591
value: 0.0
type: LocalParameter

320895
stoichiometry: 1.0
species: 377730
type: SpeciesReference

381424
units: 304591
value: 0.0
type: LocalParameter

379931
units: 304591
value: -1000.0
type: LocalParameter

382968
units: 304591
value: 13.5135135135135
type: LocalParameter

379071
kinetic law: 314678
product: 314666
reactant: 314653
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: false
type: Reaction

320679
stoichiometry: 1.0
species: 378200
type: SpeciesReference

383142
units: 304591
value: 0.0
type: LocalParameter

378879
reversible: false
product: 310538
fast: false
reactant: 310489
name: NADHdehydrogenase,mitochondrial
notes: GENE_ASSOCIATION: (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4718.1) and (4696.1) and (4694.1) and (374291.1) and (4728.1) and (4712.2) and (4717.1) and (4705.1) and (4725.1) and (4716.1) and (4537.1) and (7991.1) and (4722.1) and (4541.1) and (4539.1) and (4707.1) and (4701.1) and (4723.1) and (4698.1) and (4538.1) and (4697.1) and (51079.1) and (4714.1) and (4704.1) and (126328.1) and (4711.1) and (4724.1) and (4713.1) and (4536.1) and (4695.1) and (4702.1) and (4708.1) and (4706.1) and (4535.1) and (4731.2) and (4729.1) and (4540.1) or (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4696.1) and (4718.1) and (4694.1) and (374291.1) and (4728.1) and (7991.2) and (4717.1) and (4731.1) and (4705.1) and (4725.1) and (4537.1) and (4716.1) and (4722.1) and (4541.1) and (4539.1) and (4712.1) and (4707.1) and (4701.1) and (4723.1) and (4698.1) and (4538.1) and (4697.1) and (51079.1) and (4714.1) and (4704.1) and (126328.1) and (4711.1) and (4724.1) and (4713.1) and (4536.1) and (4695.1) and (4702.1) and (4708.1) and (4535.1) and (4706.1) and (4540.1) and (4729.1) or (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4718.1) and (4696.1) and (374291.1) and (4694.1) and (4728.1) and (7991.2) and (4712.2) and (4717.1) and (4705.1) and (4725.1) and (4716.1) and (4537.1) and (4722.1) and (4541.1) and (4539.1) and (4707.1) and (4701.1) and (4698.1) and (4723.1) and (4538.1) and (4697.1) and (51079.1) and (4714.1) and (4704.1) and (4711.1) and (126328.1) and (4724.1) and (4536.1) and (4713.1) and (4695.1) and (4702.1) and (4708.1) and (4731.2) and (4706.1) and (4535.1) and (4540.1) and (4729.1) or (4715.1) and (4720.1) and (4719.1) and (4700.1) and (55967.1) and (4709.1) and (4710.1) and (4726.1) and (4718.1) and (4696.1) and (374291.1) and (4694.1) and (4728.1) and (4717.1) and (4705.1) and (4725.1) and (…
reactant: 310513
product: 310550
type: Reaction
product: 310526
kinetic law: 310562
reactant: 310501

304819
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species: 377580
type: SpeciesReference

380474
units: 304591
value: 0.0
type: LocalParameter

377981
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Glutamate
type: Species

382021
units: 304591
value: 0.0
type: LocalParameter

382135
units: 304591
value: 1000.0
type: LocalParameter

381001
units: 304591
value: 0.0
type: LocalParameter

319749
stoichiometry: 1.0
species: 378362
type: SpeciesReference

383268
units: 304591
value: 13.5135135135135
type: LocalParameter

382308
units: 304591
value: 0.0
type: LocalParameter

381737
units: 304591
value: 1000.0
type: LocalParameter

309915
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species: 378245
type: SpeciesReference

315608
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species: 377718
type: SpeciesReference

383141
units: 304591
value: 0.0
type: LocalParameter

383266
units: 304591
value: 0.0
type: LocalParameter

382133
units: 304591
value: 0.0
type: LocalParameter

382020
units: 304591
value: 0.0
type: LocalParameter

322769
stoichiometry: 1.0
species: 378467
type: SpeciesReference

378633
notes: GENE_ASSOCIATION: (64080.1) SUBSYSTEM: Pentose Phosphate Pathway
product: 305776
reactant: 305764
reactant: 305752
type: Reaction
kinetic law: 305812
product: 305788
name: ribokinase
product: 305800
reversible: false
fast: false

379641
kinetic law: 324743
reactant: 324731
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

383267
units: 304591
value: -1000.0
type: LocalParameter

310634
stoichiometry: 2.0
species: 378053
type: SpeciesReference

382259
units: 304591
value: 0.0
type: LocalParameter

379984
units: 304591
value: 1000.0
type: LocalParameter

326250
stoichiometry: 1.0
species: 378209
type: SpeciesReference

312449
stoichiometry: 1.0
species: 378218
type: SpeciesReference

377643
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R group 6 Coenzyme A homo sapiens
type: Species

315365
stoichiometry: 1.0
species: 377969
type: SpeciesReference

317661
stoichiometry: 1.0
species: 378485
type: SpeciesReference

383140
units: 304591
value: 0.0
type: LocalParameter

321535
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species: 377577
type: SpeciesReference

325624
stoichiometry: 1.0
species: 377814
type: SpeciesReference

312244
stoichiometry: 1.0
species: 378338
type: SpeciesReference

325576
stoichiometry: 1.0
species: 378401
type: SpeciesReference

307014
stoichiometry: 1.0
species: 378083
type: SpeciesReference

381734
units: 304591
value: 0.0
type: LocalParameter

382132
units: 304591
value: 0.0
type: LocalParameter

383265
units: 304591
value: 0.0
type: LocalParameter

309042
stoichiometry: 1.0
species: 378083
type: SpeciesReference

307968
stoichiometry: 1.0
species: 377895
type: SpeciesReference

380471
units: 304591
value: 0.0
type: LocalParameter

382459
units: 304591
value: 0.0
type: LocalParameter

316357
stoichiometry: 1.0
species: 377682
type: SpeciesReference

377911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Flavin adenine dinucleotide reduced
type: Species

379644
kinetic law: 324767
reactant: 324755
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382258
units: 304591
value: 0.0
type: LocalParameter

309781
stoichiometry: 1.0
species: 378329
type: SpeciesReference

379987
units: 304591
value: 0.0
type: LocalParameter

381501
units: 304591
value: 0.0
type: LocalParameter

378876
type: Reaction
notes: GENE_ASSOCIATION: (4967.1) and (1738.1 and 8050.1) and (1743.1) or (4967.2) and (1738.1 and 8050.1) and (1743.1) SUBSYSTEM: Citric Acid Cycle
reactant: 310417
fast: false
product: 310453
reactant: 310429
product: 310465
name: 2-oxoglutaratedehydrogenase
reversible: false
product: 310441
kinetic law: 310477
reactant: 310405

318801
stoichiometry: 1.0
species: 378140
type: SpeciesReference

381735
units: 304591
value: -1000.0
type: LocalParameter

323284
stoichiometry: 1.0
species: 378281
type: SpeciesReference

378636
kinetic law: 305850
product: 305837
reactant: 305825
notes: GENE_ASSOCIATION: (5236.1) SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: true
name: phosphopentomutase
type: Reaction

383264
units: 304591
value: 13.5135135135135
type: LocalParameter

307159
stoichiometry: 1.0
species: 378185
type: SpeciesReference

324212
stoichiometry: 1.0
species: 378539
type: SpeciesReference

381428
units: 304591
value: 1000.0
type: LocalParameter

378101
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: trans-Hexadec-2-enoyl-CoA
type: Species

379581
kinetic law: 324261
reactant: 324249
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

305716
stoichiometry: 2.0
species: 378077
type: SpeciesReference

382307
units: 304591
value: 0.0
type: LocalParameter

381579
units: 304591
value: 0.0
type: LocalParameter

323849
stoichiometry: 1.0
species: 377766
type: SpeciesReference

318446
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382962
units: 304591
value: 0.0
type: LocalParameter

305194
stoichiometry: 1.0
species: 378419
type: SpeciesReference

383301
units: 304591
value: 0.0
type: LocalParameter

319182
stoichiometry: 1.0
species: 378353
type: SpeciesReference

382461
units: 304591
value: 0.0
type: LocalParameter

380725
units: 304591
value: 0.0
type: LocalParameter

380838
units: 304591
value: 1000.0
type: LocalParameter

377984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Glutamate
type: Species

306348
stoichiometry: 1.0
species: 378338
type: SpeciesReference

310889
stoichiometry: 1.0
species: 378272
type: SpeciesReference

306795
stoichiometry: 1.0
species: 378212
type: SpeciesReference

317525
stoichiometry: 1.0
species: 377793
type: SpeciesReference

321183
stoichiometry: 1.0
species: 378428
type: SpeciesReference

381218
units: 304591
value: 1000.0
type: LocalParameter

377586
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-1-Pyrroline-3-hydroxy-5-carboxylate
type: Species

382963
units: 304591
value: 0.0
type: LocalParameter

382889
units: 304591
value: 0.0
type: LocalParameter

378392
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Prostaglandin H2
type: Species

378110
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4 hydroxy retinoic acid
type: Species

380481
units: 304591
value: 0.0
type: LocalParameter

383300
units: 304591
value: 0.0
type: LocalParameter

381732
units: 304591
value: 0.0
type: LocalParameter

378639
kinetic law: 305902
product: 305889
product: 305876
reactant: 305863
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: false
name: deoxyribose-phosphatealdolase
type: Reaction

380724
units: 304591
value: 0.0
type: LocalParameter

379937
units: 304591
value: 0.0
type: LocalParameter

377649
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R total Coenzyme A
type: Species

382960
units: 304591
value: 13.5135135135135
type: LocalParameter

378059
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: H2O
type: Species

381504
units: 304591
value: 0.0
type: LocalParameter

378413
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ubiquinol-10
type: Species

377987
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glyoxylate
type: Species

382249
units: 304591
value: 0.0
type: LocalParameter

322238
stoichiometry: 1.0
species: 378218
type: SpeciesReference

377646
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: R total
type: Species

313971
stoichiometry: 1.0
species: 377960
type: SpeciesReference

382961
units: 304591
value: 0.0
type: LocalParameter

320051
stoichiometry: 1.0
species: 378227
type: SpeciesReference

381576
units: 304591
value: 1000.0
type: LocalParameter

382887
units: 304591
value: 0.0
type: LocalParameter

377697
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Adenosine
type: Species

379870
kinetic law: 326599
reactant: 326587
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Adenineexchange
type: Reaction

312813
stoichiometry: 1.0
species: 377754
type: SpeciesReference

381505
units: 304591
value: 0.0
type: LocalParameter

305940
stoichiometry: 1.0
species: 377978
type: SpeciesReference

307365
stoichiometry: 1.0
species: 378155
type: SpeciesReference

381730
units: 304591
value: 1000.0
type: LocalParameter

314798
stoichiometry: 1.0
species: 378209
type: SpeciesReference

306602
stoichiometry: 1.0
species: 378077
type: SpeciesReference

380835
units: 304591
value: 0.0
type: LocalParameter

308317
stoichiometry: 1.0
species: 378077
type: SpeciesReference

320739
stoichiometry: 1.0
species: 378227
type: SpeciesReference

379077
fast: false
kinetic law: 314774
notes: GENE_ASSOCIATION: (54407.1) SUBSYSTEM: Transport, Extracellular
product: 314750
product: 314762
reactant: 314726
type: Reaction
reactant: 314738
name: L-asparaginetransportinviasodiumsymport
reversible: false

308691
stoichiometry: 1.0
species: 378530
type: SpeciesReference

319966
stoichiometry: 1.0
species: 378089
type: SpeciesReference

304554
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

382466
units: 304591
value: 0.0
type: LocalParameter

321982
stoichiometry: 1.0
species: 378524
type: SpeciesReference

315825
stoichiometry: 1.0
species: 377850
type: SpeciesReference

323548
stoichiometry: 1.0
species: 378572
type: SpeciesReference

382966
units: 304591
value: 0.0
type: LocalParameter

378260
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: nervonic acid
type: Species

320377
stoichiometry: 1.0
species: 378212
type: SpeciesReference

377583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 1-alpha,25-Dihydroxyvitamin D3
type: Species

308185
stoichiometry: 1.0
species: 378197
type: SpeciesReference

380721
units: 304591
value: 0.0
type: LocalParameter

321305
stoichiometry: 2.0
species: 378293
type: SpeciesReference

378416
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: alpha-D-Ribose 1-phosphate
type: Species

379934
units: 304591
value: 1000.0
type: LocalParameter

311880
stoichiometry: 1.0
species: 378230
type: SpeciesReference

379140
product: 316043
fast: false
notes: GENE_ASSOCIATION: (6505.1) SUBSYSTEM: Transport, Extracellular
reactant: 315983
kinetic law: 316079
product: 316067
product: 316031
type: Reaction
reactant: 315995
product: 316055
reversible: false
reactant: 316019
reactant: 316007
name: GlutamatetransportviaNa,HsymportandKantiport

379578
product: 324188
product: 324006
product: 323801
product: 324224
product: 324164
product: 323897
reactant: 323752
reactant: 323716
product: 323958
type: Reaction
product: 324068
product: 324200
reactant: 323740
product: 324092
reactant: 323704
product: 324140
fast: false
product: 323873
reactant: 323728
product: 324018
product: 323909
product: 324116
product: 323921
notes: GENE_ASSOCIATION: SUBSYSTEM:
product: 323837
product: 324043
product: 323970
product: 323982
product: 323813
product: 324212
product: 323885
product: 324176
reactant: 323776
reversible: false
reactant: 323692
product: 323933
product: 323861
reactant: 323764
product: 324152
reactant: 323680
product: 323946
product: 324080
product: 324128
kinetic law: 324236
product: 323849
product: 324055
product: 323788
product: 324104
product: 323994
product: 323825
product: 324031

326033
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species: 378137
type: SpeciesReference

379767
kinetic law: 325756
reactant: 325744
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Oxidizedglutathioneexchange
type: Reaction

317453
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382967
units: 304591
value: 0.0
type: LocalParameter

377905
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose 6-phosphate
type: Species

320256
stoichiometry: 1.0
species: 378152
type: SpeciesReference

381574
units: 304591
value: 0.0
type: LocalParameter

325840
stoichiometry: 1.0
species: 378533
type: SpeciesReference

310803
stoichiometry: 1.0
species: 377772
type: SpeciesReference

316948
stoichiometry: 1.0
species: 377954
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318663
stoichiometry: 1.0
species: 378140
type: SpeciesReference

321208
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species: 378110
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325792
stoichiometry: 1.0
species: 377868
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382464
units: 304591
value: 1000.0
type: LocalParameter

377838
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Carnitine
type: Species

379873
kinetic law: 326623
reactant: 326611
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: CO2exchange
type: Reaction

379143
reactant: 316127
name: L-aspartatetransportviaNa,HsymportandKantiport
product: 316175
product: 316163
fast: false
kinetic law: 316187
product: 316139
reactant: 316103
reversible: false
type: Reaction
reactant: 316091
reactant: 316115
notes: GENE_ASSOCIATION: (6505.1) SUBSYSTEM: Transport, Extracellular
product: 316151

382819
units: 304591
value: 0.0
type: LocalParameter

382128
units: 304591
value: 1000.0
type: LocalParameter

381508
units: 304591
value: 1000.0
type: LocalParameter

381573
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value: 0.0
type: LocalParameter

380117
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value: 0.0
type: LocalParameter

382964
units: 304591
value: 13.5135135135135
type: LocalParameter

377908
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Flavin adenine dinucleotide oxidized
type: Species

322998
stoichiometry: 1.0
species: 377604
type: SpeciesReference

377580
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 3-Phospho-D-glyceroyl phosphate
type: Species

378056
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Hydrogen peroxide
type: Species

316622
stoichiometry: 1.0
species: 378191
type: SpeciesReference

315584
stoichiometry: 1.0
species: 377721
type: SpeciesReference

382965
units: 304591
value: 0.0
type: LocalParameter

307739
stoichiometry: 1.0
species: 377990
type: SpeciesReference

324298
stoichiometry: 1.0
species: 378521
type: SpeciesReference

381571
units: 304591
value: 0.0
type: LocalParameter

378419
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: alpha-D-Ribose 5-phosphate
type: Species

382462
units: 304591
value: -1000.0
type: LocalParameter

304639
stoichiometry: 1.0
species: 378059
type: SpeciesReference

317806
stoichiometry: 1.0
species: 377838
type: SpeciesReference

306807
stoichiometry: 1.0
species: 378077
type: SpeciesReference

MODEL1011080004
reaction: 378969
reaction: 379035
species: 377691
species: 377772
species: 378065
species: 378566
species: 378146
reaction: 379266
species: 378515
reaction: 379596
species: 377972
species: 378404
species: 377939
reaction: 379812
species: 378482
reaction: 379512
species: 377643
reaction: 379761
reaction: 379776
species: 378296
species: 378089
is described by: http://identifiers.org/pubmed/20957118
reaction: 379581
reaction: 379527
reaction: 379614
reaction: 379620
reaction: 379497
reaction: 379452
species: 377874
species: 377823
reaction: 379755
species: 378248
species: 378443
species: 377978
reaction: 379683
species: 378158
reaction: 379827
species: 377682
species: 377649
type: SBMLModel
reaction: 378780
reaction: 379179
species: 378263
reaction: 378795
species: 378314
reaction: 378816
species: 377914
reaction: 379458
reaction: 379629
species: 377619
reaction: 379158
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reaction: 378774
reaction: 378690
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species: 378125
reaction: 378636
reaction: 378924
species: 377951
reaction: 379068
reaction: 378972
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species: 377721
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reaction: 378753
reaction: 378903
reaction: 379215
species: 377559
reaction: 378918
reaction: 379545
reaction: 379389
reaction: 379047
reaction: 379053
species: 378011
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reaction: 379329

318386
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species: 378167
type: SpeciesReference

378053
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Hydrogen peroxide
type: Species

320486
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species: 377649
type: SpeciesReference

380047
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value: 0.0
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382882
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value: 0.0
type: LocalParameter

304783
stoichiometry: 1.0
species: 377933
type: SpeciesReference

381358
units: 304591
value: 1000.0
type: LocalParameter

311989
stoichiometry: 1.0
species: 378152
type: SpeciesReference

382817
units: 304591
value: 0.0
type: LocalParameter

314846
stoichiometry: 1.0
species: 377751
type: SpeciesReference

378308
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)
type: Species

379824
kinetic law: 326214
reactant: 326202
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Prolineexchange
type: Reaction

377832
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Coenzyme A
type: Species

322456
stoichiometry: 1.0
species: 378437
type: SpeciesReference

382880
units: 304591
value: 0.0
type: LocalParameter

380114
units: 304591
value: 1000.0
type: LocalParameter

313827
stoichiometry: 1.0
species: 378050
type: SpeciesReference

320147
stoichiometry: 1.0
species: 377565
type: SpeciesReference

378263
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: nervonic acid
type: Species

379876
kinetic law: 326647
reactant: 326635
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: O2exchange
type: Reaction

381158
units: 304591
value: 1000.0
type: LocalParameter

314858
stoichiometry: 1.0
species: 377748
type: SpeciesReference

382736
units: 304591
value: -1000.0
type: LocalParameter

377691
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Adenine
type: Species

309416
stoichiometry: 1.0
species: 377700
type: SpeciesReference

318775
stoichiometry: 1.0
species: 378143
type: SpeciesReference

379827
kinetic law: 326238
reactant: 326226
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Phenylalanineexchange
type: Reaction

316091
stoichiometry: 1.0
species: 377766
type: SpeciesReference

322395
stoichiometry: 1.0
species: 377682
type: SpeciesReference

381950
units: 304591
value: 0.0
type: LocalParameter

325067
stoichiometry: 1.0
species: 378338
type: SpeciesReference

382735
units: 304591
value: 0.0
type: LocalParameter

316163
stoichiometry: 1.0
species: 378143
type: SpeciesReference

319484
stoichiometry: 1.0
species: 378305
type: SpeciesReference

379764
kinetic law: 325732
reactant: 325720
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: AMPexchange
type: Reaction

382815
units: 304591
value: 1000.0
type: LocalParameter

381211
units: 304591
value: 0.0
type: LocalParameter

379879
kinetic law: 326672
reactant: 326659
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: D-Riboseexchange
type: Reaction

381951
units: 304591
value: 0.0
type: LocalParameter

321415
stoichiometry: 1.0
species: 377574
type: SpeciesReference

324104
stoichiometry: 1.0
species: 378302
type: SpeciesReference

322030
stoichiometry: 1.0
species: 377670
type: SpeciesReference

315475
stoichiometry: 1.0
species: 377966
type: SpeciesReference

379146
name: triokinase
kinetic law: 316260
type: Reaction
reactant: 316212
product: 316248
reversible: false
product: 316224
reactant: 316199
product: 316236
notes: GENE_ASSOCIATION: SUBSYSTEM: Fructose and Mannose Metabolism
fast: false

379299
kinetic law: 319001
product: 318989
reactant: 318977
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: gulonolactoneendoplasmicreticulartransport
type: Reaction

379347
kinetic law: 319797
product: 319785
reactant: 319773
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: Htransporter,peroxisome
type: Reaction

316731
stoichiometry: 1.0
species: 377622
type: SpeciesReference

378398
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Pyridoxal
type: Species

377835
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Coenzyme A
type: Species

377757
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Asparagine
type: Species

323764
stoichiometry: 1.0
species: 378563
type: SpeciesReference

324188
stoichiometry: 1.0
species: 378509
type: SpeciesReference

380834
units: 304591
value: 0.0
type: LocalParameter

382680
units: 304591
value: -1000.0
type: LocalParameter

381154
units: 304591
value: 0.0
type: LocalParameter

306457
stoichiometry: 1.0
species: 377877
type: SpeciesReference

378302
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Oxalate
type: Species

381155
units: 304591
value: 0.0
type: LocalParameter

380371
units: 304591
value: 0.0
type: LocalParameter

317189
stoichiometry: 1.0
species: 378074
type: SpeciesReference

382813
units: 304591
value: -1000.0
type: LocalParameter

320401
stoichiometry: 1.0
species: 378200
type: SpeciesReference

321293
stoichiometry: 2.0
species: 378428
type: SpeciesReference

381354
units: 304591
value: 0.0
type: LocalParameter

382733
units: 304591
value: 0.0
type: LocalParameter

380111
units: 304591
value: 0.0
type: LocalParameter

310731
stoichiometry: 4.0
species: 378077
type: SpeciesReference

379149
product: 316296
name: L-cystine/glycineexchanger(cystinein)
reactant: 316284
type: Reaction
notes: GENE_ASSOCIATION: (6519.1 and 11136.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 316321
product: 316308
reversible: false
reactant: 316272
fast: false

381841
units: 304591
value: 1000.0
type: LocalParameter

380728
units: 304591
value: 1000.0
type: LocalParameter

379293
product: 318853
kinetic law: 318879
reactant: 318827
name: K+-Cl-cotransporter(NH4+)
reactant: 318840
type: Reaction
notes: GENE_ASSOCIATION: (10723.1) SUBSYSTEM: Transport, Extracellular
reversible: true
fast: false
product: 318866

316429
stoichiometry: 1.0
species: 377832
type: SpeciesReference

381214
units: 304591
value: 0.0
type: LocalParameter

381355
units: 304591
value: 0.0
type: LocalParameter

315110
stoichiometry: 1.0
species: 377996
type: SpeciesReference

382885
units: 304591
value: 13.5135135135135
type: LocalParameter

378050
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Hydrogen peroxide
type: Species

380110
units: 304591
value: 0.0
type: LocalParameter

309344
stoichiometry: 1.0
species: 378059
type: SpeciesReference

317020
stoichiometry: 1.0
species: 378095
type: SpeciesReference

313561
stoichiometry: 1.0
species: 378212
type: SpeciesReference

323131
stoichiometry: 1.0
species: 378461
type: SpeciesReference

382682
units: 304591
value: 1000.0
type: LocalParameter

323404
stoichiometry: 1.0
species: 378047
type: SpeciesReference

310284
stoichiometry: 2.0
species: 378083
type: SpeciesReference

379296
product: 318941
reversible: true
reactant: 318917
type: Reaction
product: 318953
reactant: 318892
name: Na+-K+-Cl-cotransport(NH4+)
fast: false
notes: GENE_ASSOCIATION: (6557.1) SUBSYSTEM: Transport, Extracellular
reactant: 318905
kinetic law: 318965
product: 318929

381215
units: 304591
value: 0.0
type: LocalParameter

378266
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: O2
type: Species

377754
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Ascorbate
type: Species

377589
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 1-Pyrroline-5-carboxylate
type: Species

378395
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Prostaglandin I2
type: Species

382731
units: 304591
value: 1000.0
type: LocalParameter

377694
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Adenosine
type: Species

380831
units: 304591
value: 0.0
type: LocalParameter

381091
units: 304591
value: 0.0
type: LocalParameter

307474
stoichiometry: 1.0
species: 378077
type: SpeciesReference

311772
stoichiometry: 1.0
species: 378200
type: SpeciesReference

381151
units: 304591
value: 0.0
type: LocalParameter

306711
stoichiometry: 1.0
species: 378026
type: SpeciesReference

378410
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ubiquinone-10
type: Species

379761
kinetic law: 325708
reactant: 325696
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Reducedglutathioneexchange
type: Reaction

378305
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Oxalate
type: Species

382684
units: 304591
value: 0.0
type: LocalParameter

382812
units: 304591
value: 0.0
type: LocalParameter

382883
units: 304591
value: 0.0
type: LocalParameter

312704
stoichiometry: 1.0
species: 378242
type: SpeciesReference

383258
units: 304591
value: 0.0
type: LocalParameter

378269
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: O2
type: Species

321499
stoichiometry: 1.0
species: 377568
type: SpeciesReference

319544
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381646
units: 304591
value: 1000.0
type: LocalParameter

306954
stoichiometry: 1.0
species: 377817
type: SpeciesReference

321631
stoichiometry: 1.0
species: 378218
type: SpeciesReference

316212
stoichiometry: 1.0
species: 378002
type: SpeciesReference

383043
units: 304591
value: -1000.0
type: LocalParameter

325431
stoichiometry: 1.0
species: 378431
type: SpeciesReference

382011
units: 304591
value: 0.0
type: LocalParameter

381855
units: 304591
value: 1000.0
type: LocalParameter

379635
kinetic law: 324695
reactant: 324683
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

379994
units: 304591
value: 1000.0
type: LocalParameter

382663
units: 304591
value: 0.0
type: LocalParameter

383257
units: 304591
value: 0.0
type: LocalParameter

378996
type: Reaction
reactant: 313102
fast: false
name: glucuronolactonereductase
product: 313138
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
reactant: 313114
reversible: true
kinetic law: 313162
product: 313150
product: 313126

316960
stoichiometry: 1.0
species: 378080
type: SpeciesReference

379362
name: aldosereductase(methylglyoxal)
product: 320051
reactant: 320002
reactant: 320014
fast: false
type: Reaction
kinetic law: 320063
reversible: false
product: 320039
reactant: 320027
notes: GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1) SUBSYSTEM: Pyruvate Metabolism

310949
stoichiometry: 4.0
species: 377917
type: SpeciesReference

311166
stoichiometry: 1.0
species: 378341
type: SpeciesReference

383042
units: 304591
value: 0.0
type: LocalParameter

380064
units: 304591
value: 1000.0
type: LocalParameter

317261
stoichiometry: 1.0
species: 377697
type: SpeciesReference

378539
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Valine
type: Species

318892
stoichiometry: 2.0
species: 377814
type: SpeciesReference

382093
units: 304591
value: 1000.0
type: LocalParameter

380611
units: 304591
value: 0.0
type: LocalParameter

382014
units: 304591
value: -1000.0
type: LocalParameter

381648
units: 304591
value: 0.0
type: LocalParameter

379365
reversible: false
reactant: 320075
type: Reaction
reactant: 320099
notes: GENE_ASSOCIATION: (10327.2) or (8574.1) or (10327.1) or (231.1) SUBSYSTEM: Pyruvate Metabolism
kinetic law: 320135
fast: false
product: 320111
reactant: 320087
product: 320123
name: aldosereductase(acetol)

310538
stoichiometry: 1.0
species: 378215
type: SpeciesReference

306880
stoichiometry: 1.0
species: 378185
type: SpeciesReference

317092
stoichiometry: 2.0
species: 378092
type: SpeciesReference

379128
reactant: 315777
reactant: 315765
reversible: true
product: 315801
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
type: Reaction
kinetic law: 315813
product: 315789
fast: false
name: L-cysteine/L-glutaminereversibleexchanger

315243
stoichiometry: 1.0
species: 377969
type: SpeciesReference

381375
units: 304591
value: 0.0
type: LocalParameter

382517
units: 304591
value: 0.0
type: LocalParameter

383045
units: 304591
value: 0.0
type: LocalParameter

381374
units: 304591
value: 0.0
type: LocalParameter

381857
units: 304591
value: 0.0
type: LocalParameter

320534
stoichiometry: 1.0
species: 377643
type: SpeciesReference

321099
stoichiometry: 2.0
species: 378077
type: SpeciesReference

382090
units: 304591
value: 0.0
type: LocalParameter

381969
units: 304591
value: 0.0
type: LocalParameter

382661
units: 304591
value: 1000.0
type: LocalParameter

306120
stoichiometry: 1.0
species: 377769
type: SpeciesReference

322889
stoichiometry: 1.0
species: 377739
type: SpeciesReference

378536
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Valine
type: Species

380691
units: 304591
value: 0.0
type: LocalParameter

382013
units: 304591
value: 0.0
type: LocalParameter

310417
stoichiometry: 1.0
species: 377829
type: SpeciesReference

383259
units: 304591
value: -1000.0
type: LocalParameter

379410
kinetic law: 321051
reversible: true
reactant: 321003
reactant: 320979
product: 321039
fast: false
reactant: 320991
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
product: 321015
product: 321027
name: retinaldehydrogenase
type: Reaction

380351
units: 304591
value: 0.0
type: LocalParameter

315704
stoichiometry: 1.0
species: 377966
type: SpeciesReference

383044
units: 304591
value: 0.0
type: LocalParameter

378918
notes: GENE_ASSOCIATION: (2746.1) SUBSYSTEM: Glutamate metabolism
reactant: 311384
reactant: 311396
reversible: true
product: 311420
fast: false
type: Reaction
kinetic law: 311456
name: glutamatedehydrogenase(NADP),mitochondrial
product: 311408
product: 311444
product: 311432
reactant: 311372

378999
product: 313198
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Ascorbate and Aldarate Metabolism
reactant: 313186
reactant: 313174
product: 313210
name: uronolactonase,endoplasmicreticulum
reversible: true
fast: false
kinetic law: 313222

380130
units: 304591
value: 0.0
type: LocalParameter

382091
units: 304591
value: -1000.0
type: LocalParameter

307848
stoichiometry: 1.0
species: 378437
type: SpeciesReference

378993
product: 313054
reversible: false
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
product: 313066
reactant: 313029
kinetic law: 313090
fast: false
reactant: 313017
reactant: 313041
name: glycineoxidase,perixosomal
product: 313078

381431
units: 304591
value: 0.0
type: LocalParameter

379212
notes: GENE_ASSOCIATION: (6526.1) or (159963.1) or (6524.1) SUBSYSTEM: Transport, Extracellular
reactant: 317393
name: glucosetransportviasodiumsymport
fast: false
reactant: 317381
product: 317417
type: Reaction
kinetic law: 317429
product: 317405
reversible: true

313102
stoichiometry: 1.0
species: 378032
type: SpeciesReference

383048
units: 304591
value: 13.5135135135135
type: LocalParameter

379991
units: 304591
value: -1000.0
type: LocalParameter

382515
units: 304591
value: 0.0
type: LocalParameter

382016
units: 304591
value: 0.0
type: LocalParameter

382668
units: 304591
value: 1000.0
type: LocalParameter

314906
stoichiometry: 1.0
species: 378188
type: SpeciesReference

307582
stoichiometry: 1.0
species: 377817
type: SpeciesReference

380468
units: 304591
value: 1000.0
type: LocalParameter

380588
units: 304591
value: 1000.0
type: LocalParameter

380355
units: 304591
value: -1000.0
type: LocalParameter

382261
units: 304591
value: 1000.0
type: LocalParameter

312026
stoichiometry: 1.0
species: 378227
type: SpeciesReference

381967
units: 304591
value: 1000.0
type: LocalParameter

381859
units: 304591
value: 0.0
type: LocalParameter

378915
kinetic law: 311360
product: 311348
reactant: 311287
fast: false
reactant: 311275
product: 311323
product: 311311
reactant: 311299
reversible: true
type: Reaction
notes: GENE_ASSOCIATION: (2746.1) SUBSYSTEM: Glutamate metabolism
product: 311336

383047
units: 304591
value: 0.0
type: LocalParameter

314224
stoichiometry: 1.0
species: 377631
type: SpeciesReference

381641
units: 304591
value: 0.0
type: LocalParameter

379990
units: 304591
value: 0.0
type: LocalParameter

313174
stoichiometry: 1.0
species: 377963
type: SpeciesReference

380694
units: 304591
value: 0.0
type: LocalParameter

382097
units: 304591
value: 0.0
type: LocalParameter

380354
units: 304591
value: 0.0
type: LocalParameter

322805
stoichiometry: 1.0
species: 377775
type: SpeciesReference

311287
stoichiometry: 1.0
species: 378065
type: SpeciesReference

321003
stoichiometry: 1.0
species: 378425
type: SpeciesReference

311556
stoichiometry: 1.0
species: 378506
type: SpeciesReference

380615
units: 304591
value: -1000.0
type: LocalParameter

324466
stoichiometry: 1.0
species: 378536
type: SpeciesReference

324731
stoichiometry: 1.0
species: 378104
type: SpeciesReference

381371
units: 304591
value: 0.0
type: LocalParameter

383046
units: 304591
value: 0.0
type: LocalParameter

378882
type: Reaction
reactant: 310586
product: 310598
name: alpha-ketoglutarate/malatetransporter
kinetic law: 310622
product: 310610
reactant: 310574
reversible: true
notes: GENE_ASSOCIATION: (8402.1) SUBSYSTEM: Transport, Mitochondrial
fast: false

316586
stoichiometry: 1.0
species: 378539
type: SpeciesReference

381644
units: 304591
value: 0.0
type: LocalParameter

382666
units: 304591
value: 0.0
type: LocalParameter

381138
units: 304591
value: 1000.0
type: LocalParameter

382513
units: 304591
value: 1000.0
type: LocalParameter

305876
stoichiometry: 1.0
species: 377661
type: SpeciesReference

378533
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Urea
type: Species

379413
product: 321111
reversible: true
type: Reaction
reactant: 321075
product: 321099
kinetic law: 321135
product: 321123
name: retinaldehydrogenase(NADPH)
reactant: 321087
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
reactant: 321063

382018
units: 304591
value: 0.0
type: LocalParameter

381965
units: 304591
value: -1000.0
type: LocalParameter

380695
units: 304591
value: 0.0
type: LocalParameter

382263
units: 304591
value: 0.0
type: LocalParameter

306012
stoichiometry: 1.0
species: 378404
type: SpeciesReference

313899
stoichiometry: 1.0
species: 377700
type: SpeciesReference

380614
units: 304591
value: 0.0
type: LocalParameter

309572
stoichiometry: 1.0
species: 377700
type: SpeciesReference

318929
stoichiometry: 2.0
species: 377811
type: SpeciesReference

381434
units: 304591
value: 0.0
type: LocalParameter

381643
units: 304591
value: 0.0
type: LocalParameter

383049
units: 304591
value: 0.0
type: LocalParameter

321740
stoichiometry: 2.0
species: 378266
type: SpeciesReference

380067
units: 304591
value: 0.0
type: LocalParameter

379368
reactant: 320159
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Pyruvate Metabolism
type: Reaction
reversible: false
reactant: 320147
product: 320183
product: 320171
name: alcoholdehydrogenase(L-1,2-propanediol)
fast: false
kinetic law: 320208
product: 320195

314115
stoichiometry: 1.0
species: 378059
type: SpeciesReference

382665
units: 304591
value: 0.0
type: LocalParameter

382095
units: 304591
value: 0.0
type: LocalParameter

381964
units: 304591
value: 0.0
type: LocalParameter

309854
stoichiometry: 1.0
species: 378446
type: SpeciesReference

379638
kinetic law: 324719
reactant: 324707
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

308269
stoichiometry: 1.0
species: 378377
type: SpeciesReference

380508
units: 304591
value: 1000.0
type: LocalParameter

311444
stoichiometry: 1.0
species: 378251
type: SpeciesReference

378801
reactant: 308861
kinetic law: 308922
reactant: 308873
product: 308886
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: (64080.1) SUBSYSTEM: Pentose Phosphate Pathway
product: 308910
product: 308898
name: Deoxyribokinase
fast: false

324394
stoichiometry: 1.0
species: 378563
type: SpeciesReference

312437
stoichiometry: 1.0
species: 378077
type: SpeciesReference

308113
stoichiometry: 1.0
species: 377942
type: SpeciesReference

381591
units: 304591
value: 0.0
type: LocalParameter

323620
stoichiometry: 1.0
species: 378059
type: SpeciesReference

383156
units: 304591
value: 13.5135135135135
type: LocalParameter

321800
stoichiometry: 1.0
species: 377745
type: SpeciesReference

382265
units: 304591
value: 0.0
type: LocalParameter

380584
units: 304591
value: 0.0
type: LocalParameter

380464
units: 304591
value: 0.0
type: LocalParameter

382511
units: 304591
value: 0.0
type: LocalParameter

382957
units: 304591
value: 0.0
type: LocalParameter

382443
units: 304591
value: 1000.0
type: LocalParameter

313066
stoichiometry: 1.0
species: 378056
type: SpeciesReference

313549
stoichiometry: 1.0
species: 378197
type: SpeciesReference

307691
stoichiometry: 2.0
species: 378083
type: SpeciesReference

382125
units: 304591
value: 0.0
type: LocalParameter

382266
units: 304591
value: -1000.0
type: LocalParameter

378116
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Hypoxanthine
type: Species

383157
units: 304591
value: 0.0
type: LocalParameter

379572
kinetic law: 323596
product: 323584
reactant: 323572
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

314199
stoichiometry: 1.0
species: 377769
type: SpeciesReference

381435
units: 304591
value: -1000.0
type: LocalParameter

311396
stoichiometry: 1.0
species: 378230
type: SpeciesReference

381592
units: 304591
value: 0.0
type: LocalParameter

378912
name: methenyltetrahydrofolatecyclohydrolase
fast: false
reactant: 311227
reactant: 311215
kinetic law: 311263
type: Reaction
reversible: true
notes: GENE_ASSOCIATION: (4522.1) or (285216.1) or (80068.1) SUBSYSTEM: Folate Metabolism
product: 311239
product: 311251

378807
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
product: 309042
name: acetatemitochondrialtransportviaprotonsymport
fast: false
reactant: 309018
reversible: true
reactant: 309006
kinetic law: 309054
product: 309030
type: Reaction

383155
units: 304591
value: 0.0
type: LocalParameter

377990
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Glyoxylate
type: Species

380358
units: 304591
value: 1000.0
type: LocalParameter

380585
units: 304591
value: -1000.0
type: LocalParameter

317008
stoichiometry: 1.0
species: 377811
type: SpeciesReference

380698
units: 304591
value: 1000.0
type: LocalParameter

382510
units: 304591
value: 0.0
type: LocalParameter

319315
stoichiometry: 1.0
species: 377700
type: SpeciesReference

378530
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Urea
type: Species

377904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose 1-phosphate
type: Species

379416
name: retinoicacidhydroxylation(P450)
fast: false
reactant: 321171
product: 321221
reactant: 321183
kinetic law: 321233
product: 321208
product: 321196
reactant: 321147
reversible: false
reactant: 321159
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism

382956
units: 304591
value: 13.5135135135135
type: LocalParameter

380618
units: 304591
value: 1000.0
type: LocalParameter

378804
product: 308982
reversible: false
fast: false
kinetic law: 308994
product: 308970
reactant: 308946
notes: GENE_ASSOCIATION: (6652.1) SUBSYSTEM: Fructose and Mannose Metabolism
reactant: 308934
name: D-sorbitoldehydrogenase(D-fructoseproducing)
product: 308958
type: Reaction

380505
units: 304591
value: -1000.0
type: LocalParameter

320943
stoichiometry: 1.0
species: 378374
type: SpeciesReference

383251
units: 304591
value: -1000.0
type: LocalParameter

378119
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Isocitrate
type: Species

382268
units: 304591
value: 1000.0
type: LocalParameter

382445
units: 304591
value: 0.0
type: LocalParameter

382959
units: 304591
value: 0.0
type: LocalParameter

379062
fast: false
reversible: false
type: Reaction
product: 314545
notes: GENE_ASSOCIATION: (1594.1) SUBSYSTEM: Vitamin D
kinetic law: 314569
reactant: 314496
product: 314533
product: 314557
reactant: 314509
reactant: 314484
name: 1-alpha-VitaminD-25-hydroxylase(D3)
reactant: 314521

378642
notes: GENE_ASSOCIATION: (2805.1) SUBSYSTEM: Alanine and Aspartate Metabolism
reversible: true
reactant: 305928
fast: false
product: 305940
kinetic law: 305964
name: aspartatetransaminase
product: 305952
reactant: 305915
type: Reaction

377901
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Ethanol
type: Species

383159
units: 304591
value: -1000.0
type: LocalParameter

380504
units: 304591
value: 0.0
type: LocalParameter

381594
units: 304591
value: 1000.0
type: LocalParameter

380465
units: 304591
value: 0.0
type: LocalParameter

379419
kinetic law: 321269
product: 321257
reactant: 321245
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 4-hydroxyretinoicacidtransport,Nuclear
type: Reaction

383250
units: 304591
value: 0.0
type: LocalParameter

325359
stoichiometry: 1.0
species: 377577
type: SpeciesReference

382126
units: 304591
value: 0.0
type: LocalParameter

378990
reactant: 312945
type: Reaction
reactant: 312957
fast: false
kinetic law: 313005
reversible: false
product: 312993
product: 312981
name: dehydroascorbatereductase
reactant: 312969
notes: GENE_ASSOCIATION: (2745.1) SUBSYSTEM: Ascorbate and Aldarate Metabolism

382958
units: 304591
value: 0.0
type: LocalParameter

379575
reactant: 323620
product: 323644
kinetic law: 323668
reversible: false
type: Reaction
product: 323656
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM:
product: 323632
reactant: 323608

381438
units: 304591
value: 1000.0
type: LocalParameter

378885
kinetic law: 310671
product: 310659
product: 310646
reactant: 310634
notes: GENE_ASSOCIATION: (847.1) SUBSYSTEM: ROS Detoxification
fast: false
reversible: false
name: catalase
type: Reaction

383158
units: 304591
value: 0.0
type: LocalParameter

378194
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 5,10-Methenyltetrahydrofolate
type: Species

307956
stoichiometry: 1.0
species: 377898
type: SpeciesReference

324068
stoichiometry: 1.0
species: 378176
type: SpeciesReference

322018
stoichiometry: 1.0
species: 378056
type: SpeciesReference

383253
units: 304591
value: 0.0
type: LocalParameter

309030
stoichiometry: 1.0
species: 377658
type: SpeciesReference

307002
stoichiometry: 1.0
species: 378338
type: SpeciesReference

380061
units: 304591
value: -1000.0
type: LocalParameter

383152
units: 304591
value: 0.0
type: LocalParameter

315050
stoichiometry: 1.0
species: 378077
type: SpeciesReference

308619
stoichiometry: 1.0
species: 378080
type: SpeciesReference

381746
units: 304591
value: 0.0
type: LocalParameter

311336
stoichiometry: 1.0
species: 378221
type: SpeciesReference

305728
stoichiometry: 1.0
species: 378236
type: SpeciesReference

378888
reactant: 310695
type: Reaction
notes: GENE_ASSOCIATION: (7384.1) and (7388.1) and (4519.1) and (29796.2) and (10975.1) and (7385.1) and (7386.1) and (1537.1) and (27089.1) and (7381.1) or (7384.1) and (7388.1) and (4519.1) and (29796.1) and (10975.1) and (7385.1) and (1537.1) and (7386.1) and (27089.1) and (7381.1) SUBSYSTEM: Oxidative Phosphorylation
fast: false
product: 310743
product: 310719
reversible: false
kinetic law: 310755
product: 310731
reactant: 310707
reactant: 310683
name: ubiquinol-6cytochromecreductase,ComplexIII

378197
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 5,10-Methylenetetrahydrofolate
type: Species

382447
units: 304591
value: 0.0
type: LocalParameter

383302
units: 304591
value: 0.0
type: LocalParameter

316369
stoichiometry: 1.0
species: 377826
type: SpeciesReference

379632
kinetic law: 324671
reactant: 324659
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

322540
stoichiometry: 1.0
species: 378317
type: SpeciesReference

378648
reactant: 306048
reactant: 306036
reversible: false
notes: GENE_ASSOCIATION: (132.1) or (132.2) SUBSYSTEM: Nucleotides
kinetic law: 306096
fast: false
product: 306060
product: 306084
product: 306072
name: adenosinekinase
type: Reaction

320039
stoichiometry: 1.0
species: 377679
type: SpeciesReference

304939
stoichiometry: 1.0
species: 377769
type: SpeciesReference

305928
stoichiometry: 1.0
species: 377763
type: SpeciesReference

383252
units: 304591
value: 0.0
type: LocalParameter

324200
stoichiometry: 1.0
species: 378518
type: SpeciesReference

313489
stoichiometry: 1.0
species: 378008
type: SpeciesReference

383151
units: 304591
value: -1000.0
type: LocalParameter

380060
units: 304591
value: 0.0
type: LocalParameter

323296
stoichiometry: 1.0
species: 378287
type: SpeciesReference

325648
stoichiometry: 1.0
species: 377784
type: SpeciesReference

316851
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382448
units: 304591
value: 0.0
type: LocalParameter

378113
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 4 hydroxy retinoic acid
type: Species

383255
units: 304591
value: -1000.0
type: LocalParameter

380501
units: 304591
value: 0.0
type: LocalParameter

326515
stoichiometry: 1.0
species: 377727
type: SpeciesReference

377993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glycine
type: Species

381748
units: 304591
value: 0.0
type: LocalParameter

383154
units: 304591
value: 0.0
type: LocalParameter

309928
stoichiometry: 1.0
species: 378542
type: SpeciesReference

380581
units: 304591
value: 0.0
type: LocalParameter

379997
units: 304591
value: 0.0
type: LocalParameter

382123
units: 304591
value: 0.0
type: LocalParameter

319737
stoichiometry: 1.0
species: 378359
type: SpeciesReference

380461
units: 304591
value: 0.0
type: LocalParameter

383256
units: 304591
value: 13.5135135135135
type: LocalParameter

383254
units: 304591
value: 0.0
type: LocalParameter

308485
stoichiometry: 1.0
species: 378047
type: SpeciesReference

382121
units: 304591
value: 0.0
type: LocalParameter

324514
stoichiometry: 1.0
species: 378506
type: SpeciesReference

383153
units: 304591
value: 0.0
type: LocalParameter

381749
units: 304591
value: -1000.0
type: LocalParameter

321523
stoichiometry: 1.0
species: 377574
type: SpeciesReference

377631
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: 4-Pyridoxate
type: Species

315353
stoichiometry: 1.0
species: 378452
type: SpeciesReference

378645
reactant: 305976
name: L-alaninetransaminase
reversible: true
product: 306012
type: Reaction
fast: false
kinetic law: 306024
product: 306000
reactant: 305988
notes: GENE_ASSOCIATION: (2875.1) SUBSYSTEM: Glutamate metabolism

310646
stoichiometry: 2.0
species: 378065
type: SpeciesReference

317745
stoichiometry: 1.0
species: 377796
type: SpeciesReference

378047
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Hydrogen peroxide
type: Species

381298
units: 304591
value: 1000.0
type: LocalParameter

378425
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Retinal
type: Species

379569
kinetic law: 323560
product: 323548
reactant: 323536
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

377999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Glycine
type: Species

380791
units: 304591
value: 0.0
type: LocalParameter

308041
stoichiometry: 1.0
species: 377772
type: SpeciesReference

380711
units: 304591
value: 0.0
type: LocalParameter

322310
stoichiometry: 2.0
species: 378077
type: SpeciesReference

312921
stoichiometry: 1.0
species: 378011
type: SpeciesReference

380824
units: 304591
value: 0.0
type: LocalParameter

379882
kinetic law: 326696
reactant: 326684
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: myo-Inositolexchange
type: Reaction

382899
units: 304591
value: 13.5135135135135
type: LocalParameter

377634
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Cystine
type: Species

379068
kinetic law: 314641
product: 314629
reactant: 314617
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
name: 25-hydroxyvitaminD3transportincytoplasm
type: Reaction

381588
units: 304591
value: 0.0
type: LocalParameter

312825
stoichiometry: 2.0
species: 378077
type: SpeciesReference

381208
units: 304591
value: 1000.0
type: LocalParameter

312655
stoichiometry: 1.0
species: 378557
type: SpeciesReference

308329
stoichiometry: 1.0
species: 377984
type: SpeciesReference

320727
stoichiometry: 1.0
species: 378200
type: SpeciesReference

321909
stoichiometry: 1.0
species: 378356
type: SpeciesReference

307353
stoichiometry: 1.0
species: 378059
type: SpeciesReference

306614
stoichiometry: 1.0
species: 378257
type: SpeciesReference

319809
stoichiometry: 1.0
species: 377993
type: SpeciesReference

381742
units: 304591
value: -1000.0
type: LocalParameter

379927
units: 304591
value: 0.0
type: LocalParameter

318458
stoichiometry: 1.0
species: 378263
type: SpeciesReference

381205
units: 304591
value: 0.0
type: LocalParameter

314448
stoichiometry: 1.0
species: 378350
type: SpeciesReference

305425
stoichiometry: 1.0
species: 377933
type: SpeciesReference

323837
stoichiometry: 1.0
species: 377760
type: SpeciesReference

382950
units: 304591
value: 0.0
type: LocalParameter

310877
stoichiometry: 1.0
species: 378053
type: SpeciesReference

314091
stoichiometry: 1.0
species: 378398
type: SpeciesReference

377996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Glycine
type: Species

306336
stoichiometry: 1.0
species: 377865
type: SpeciesReference

378122
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Isoleucine
type: Species

378311
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)
type: Species

382740
units: 304591
value: 0.0
type: LocalParameter

321171
stoichiometry: 1.0
species: 378266
type: SpeciesReference

317513
stoichiometry: 1.0
species: 378209
type: SpeciesReference

377598
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: 25-Hydroxyvitamin D3
type: Species

382951
units: 304591
value: 0.0
type: LocalParameter

383150
units: 304591
value: 0.0
type: LocalParameter

377637
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Cystine
type: Species

310188
stoichiometry: 1.0
species: 377975
type: SpeciesReference

310200
stoichiometry: 1.0
species: 377589
type: SpeciesReference

309706
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381744
units: 304591
value: 1000.0
type: LocalParameter

380825
units: 304591
value: 0.0
type: LocalParameter

381585
units: 304591
value: 1000.0
type: LocalParameter

382952
units: 304591
value: 13.5135135135135
type: LocalParameter

318012
stoichiometry: 1.0
species: 377706
type: SpeciesReference

379131
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
reactant: 315825
reversible: true
product: 315850
product: 315862
name: L-cysteine/glycinereversibleexchanger
reactant: 315837
fast: false
kinetic law: 315874

379885
kinetic law: 326721
reactant: 326709
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Glutamineexchange
type: Reaction

382116
units: 304591
value: 0.0
type: LocalParameter

315680
stoichiometry: 1.0
species: 378500
type: SpeciesReference

312473
stoichiometry: 1.0
species: 377613
type: SpeciesReference

380828
units: 304591
value: 1000.0
type: LocalParameter

379924
units: 304591
value: 1000.0
type: LocalParameter

307221
stoichiometry: 1.0
species: 378059
type: SpeciesReference

305073
stoichiometry: 1.0
species: 377616
type: SpeciesReference

378044
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: carbonic acid
type: Species

382953
units: 304591
value: 0.0
type: LocalParameter

316634
stoichiometry: 1.0
species: 378188
type: SpeciesReference

382808
units: 304591
value: 1000.0
type: LocalParameter

377592
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2,3-Disphospho-D-glycerate
type: Species

382450
units: 304591
value: 1000.0
type: LocalParameter

377595
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 25-Hydroxyvitamin D3
type: Species

316139
stoichiometry: 1.0
species: 377763
type: SpeciesReference

382954
units: 304591
value: 0.0
type: LocalParameter

320365
stoichiometry: 1.0
species: 378155
type: SpeciesReference

378272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: O2
type: Species

379065
kinetic law: 314605
product: 314593
reactant: 314581
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
type: Reaction

382118
units: 304591
value: 0.0
type: LocalParameter

319954
stoichiometry: 1.0
species: 377835
type: SpeciesReference

379921
units: 304591
value: 0.0
type: LocalParameter

382454
units: 304591
value: 0.0
type: LocalParameter

304566
exponent: -1.0
scale: 0
multipler: 1.0
kind: GRAM
type: SBMLUnit

324947
stoichiometry: 1.0
species: 377951
type: SpeciesReference

323332
stoichiometry: 1.0
species: 378284
type: SpeciesReference

378428
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Retinoate
type: Species

381741
units: 304591
value: 0.0
type: LocalParameter

378191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Methionine
type: Species

382955
units: 304591
value: 0.0
type: LocalParameter

311009
stoichiometry: 1.0
species: 377667
type: SpeciesReference

312509
stoichiometry: 1.0
species: 378560
type: SpeciesReference

320268
stoichiometry: 1.0
species: 378218
type: SpeciesReference

382119
units: 304591
value: -1000.0
type: LocalParameter

379779
kinetic law: 325852
reactant: 325840
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Ureaexchange
type: Reaction

379920
units: 304591
value: 0.0
type: LocalParameter

317441
stoichiometry: 1.0
species: 378131
type: SpeciesReference

379566
kinetic law: 323524
product: 323512
reactant: 323500
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

382452
units: 304591
value: 0.0
type: LocalParameter

318675
stoichiometry: 1.0
species: 378206
type: SpeciesReference

326733
stoichiometry: 1.0
species: 377805
type: SpeciesReference

309404
stoichiometry: 1.0
species: 378467
type: SpeciesReference

305341
stoichiometry: 1.0
species: 378551
type: SpeciesReference

308739
stoichiometry: 1.0
species: 378056
type: SpeciesReference

381962
units: 304591
value: 0.0
type: LocalParameter

379815
kinetic law: 326142
reactant: 326130
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Tyrosineexchange
type: Reaction

319472
stoichiometry: 1.0
species: 378089
type: SpeciesReference

307171
stoichiometry: 1.0
species: 377808
type: SpeciesReference

381145
units: 304591
value: 0.0
type: LocalParameter

382747
units: 304591
value: 0.0
type: LocalParameter

379776
kinetic law: 325828
reactant: 325816
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Acetaldehydeexchange
type: Reaction

382007
units: 304591
value: 0.0
type: LocalParameter

317104
stoichiometry: 1.0
species: 378206
type: SpeciesReference

382803
units: 304591
value: 0.0
type: LocalParameter

379203
kinetic law: 317249
reactant: 317189
name: xanthineoxidase,peroxisomal
product: 317225
type: Reaction
fast: false
reactant: 317213
reactant: 317201
product: 317237
notes: GENE_ASSOCIATION: (7498.1) SUBSYSTEM: Purine Catabolism
reversible: false

316151
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382890
units: 304591
value: 0.0
type: LocalParameter

377748
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Arginine
type: Species

380718
units: 304591
value: 1000.0
type: LocalParameter

379287
type: Reaction
notes: GENE_ASSOCIATION: (6559.1) SUBSYSTEM: Transport, Extracellular
reversible: false
product: 318724
name: Na+-Cl-cotransport
reactant: 318712
product: 318736
kinetic law: 318749
reactant: 318699
fast: false

316743
stoichiometry: 2.0
species: 378209
type: SpeciesReference

379359
name: peroxisomalacyl-CoAthioesterase
reactant: 319929
notes: GENE_ASSOCIATION: (10965.1) SUBSYSTEM: Fatty Acid Metabolism
fast: false
product: 319954
reactant: 319942
reversible: false
product: 319978
type: Reaction
product: 319966
kinetic law: 319990

377847
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: cervonic acid, C22:6 n-3
type: Species

381144
units: 304591
value: 0.0
type: LocalParameter

315463
stoichiometry: 1.0
species: 377727
type: SpeciesReference

305292
stoichiometry: 1.0
species: 377892
type: SpeciesReference

380124
units: 304591
value: 0.0
type: LocalParameter

320473
stoichiometry: 1.0
species: 377640
type: SpeciesReference

379134
fast: false
product: 315922
kinetic law: 315934
reversible: true
product: 315910
type: Reaction
reactant: 315898
reactant: 315886
notes: GENE_ASSOCIATION: SUBSYSTEM: Cysteine Metabolism
name: Glutathione:cystineoxidoreductase

380798
units: 304591
value: 1000.0
type: LocalParameter

381291
units: 304591
value: 0.0
type: LocalParameter

381960
units: 304591
value: 1000.0
type: LocalParameter

381850
units: 304591
value: 0.0
type: LocalParameter

322043
stoichiometry: 2.0
species: 378074
type: SpeciesReference

382805
units: 304591
value: 0.0
type: LocalParameter

304831
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382749
units: 304591
value: 0.0
type: LocalParameter

379812
kinetic law: 326118
reactant: 326106
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Valineexchange
type: Reaction

382009
units: 304591
value: 1000.0
type: LocalParameter

377844
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: cervonic acid, C22:6 n-3
type: Species

317599
stoichiometry: 2.0
species: 378206
type: SpeciesReference

378041
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: L-Gulonate
type: Species

315922
stoichiometry: 1.0
species: 378011
type: SpeciesReference

318398
stoichiometry: 1.0
species: 378209
type: SpeciesReference

380127
units: 304591
value: 0.0
type: LocalParameter

382894
units: 304591
value: 0.0
type: LocalParameter

311808
stoichiometry: 1.0
species: 378227
type: SpeciesReference

322468
stoichiometry: 1.0
species: 378434
type: SpeciesReference

305231
stoichiometry: 1.0
species: 378440
type: SpeciesReference

382892
units: 304591
value: 13.5135135135135
type: LocalParameter

382098
units: 304591
value: -1000.0
type: LocalParameter

379888
kinetic law: 326745
reactant: 326733
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Citrateexchange
type: Reaction

382806
units: 304591
value: -1000.0
type: LocalParameter

326130
stoichiometry: 1.0
species: 378518
type: SpeciesReference

304627
stoichiometry: 1.0
species: 377610
type: SpeciesReference

313815
stoichiometry: 2.0
species: 378020
type: SpeciesReference

320751
stoichiometry: 2.0
species: 378077
type: SpeciesReference

378275
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: O2
type: Species

320159
stoichiometry: 1.0
species: 378212
type: SpeciesReference

382670
units: 304591
value: 0.0
type: LocalParameter

323933
stoichiometry: 1.0
species: 377981
type: SpeciesReference

378317
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)
type: Species

377841
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Carnitine
type: Species

380715
units: 304591
value: 0.0
type: LocalParameter

381852
units: 304591
value: 0.0
type: LocalParameter

310296
stoichiometry: 1.0
species: 378221
type: SpeciesReference

309356
stoichiometry: 1.0
species: 377730
type: SpeciesReference

312170
stoichiometry: 1.0
species: 378395
type: SpeciesReference

322901
stoichiometry: 1.0
species: 377745
type: SpeciesReference

380120
units: 304591
value: 0.0
type: LocalParameter

380121
units: 304591
value: -1000.0
type: LocalParameter

382743
units: 304591
value: -1000.0
type: LocalParameter

381368
units: 304591
value: 1000.0
type: LocalParameter

377742
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: arachidonic acid
type: Species

382896
units: 304591
value: 0.0
type: LocalParameter

379284
reactant: 318627
product: 318663
kinetic law: 318687
type: Reaction
product: 318675
reversible: true
reactant: 318615
reactant: 318639
name: Na+-K+-Cl-cotransport
fast: false
notes: GENE_ASSOCIATION: (6557.1) SUBSYSTEM: Transport, Extracellular
product: 318651

305389
stoichiometry: 1.0
species: 377892
type: SpeciesReference

378278
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: O2
type: Species

323144
stoichiometry: 1.0
species: 378464
type: SpeciesReference

311760
stoichiometry: 1.0
species: 378077
type: SpeciesReference

314653
stoichiometry: 1.0
species: 377595
type: SpeciesReference

307462
stoichiometry: 1.0
species: 377661
type: SpeciesReference

306723
stoichiometry: 1.0
species: 378491
type: SpeciesReference

379818
kinetic law: 326166
reactant: 326154
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Threonineexchange
type: Reaction

380714
units: 304591
value: 0.0
type: LocalParameter

326443
stoichiometry: 1.0
species: 377766
type: SpeciesReference

379209
reactant: 317333
reactant: 317321
product: 317357
product: 317345
type: Reaction
kinetic law: 317369
notes: GENE_ASSOCIATION: (64078.1) SUBSYSTEM: Transport, Extracellular
fast: false
name: inosinetransportinviasodium(1:2)symport
reversible: false

382742
units: 304591
value: 0.0
type: LocalParameter

312716
stoichiometry: 1.0
species: 378041
type: SpeciesReference

381204
units: 304591
value: 0.0
type: LocalParameter

311917
stoichiometry: 1.0
species: 377772
type: SpeciesReference

378422
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: cis-13-retinal
type: Species

379773
kinetic law: 325804
reactant: 325792
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Deoxyguanosineexchange
type: Reaction

381295
units: 304591
value: -1000.0
type: LocalParameter

318240
stoichiometry: 1.0
species: 377706
type: SpeciesReference

380794
units: 304591
value: 0.0
type: LocalParameter

377745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: arachidonic acid
type: Species

323776
stoichiometry: 1.0
species: 378569
type: SpeciesReference

383040
units: 304591
value: 13.5135135135135
type: LocalParameter

324176
stoichiometry: 1.0
species: 378503
type: SpeciesReference

379137
kinetic law: 315971
product: 315958
reactant: 315946
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
name: glucosetransportviamembranevesicle
type: Reaction

314557
stoichiometry: 1.0
species: 378230
type: SpeciesReference

321281
stoichiometry: 1.0
species: 378266
type: SpeciesReference

379770
kinetic law: 325780
reactant: 325768
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Deoxyinosineexchange
type: Reaction

382801
units: 304591
value: 1000.0
type: LocalParameter

382745
units: 304591
value: 1000.0
type: LocalParameter

305644
stoichiometry: 1.0
species: 378218
type: SpeciesReference

381201
units: 304591
value: 0.0
type: LocalParameter

378314
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)
type: Species

309259
stoichiometry: 1.0
species: 378227
type: SpeciesReference

306699
stoichiometry: 1.0
species: 377829
type: SpeciesReference

378909
product: 311191
product: 311179
fast: false
reactant: 311166
type: Reaction
notes: GENE_ASSOCIATION: (6569.1) SUBSYSTEM: Transport, Extracellular
reactant: 311154
reversible: true
kinetic law: 311203
name: phosphatetransportin/outviathreeNa+symporter

381853
units: 304591
value: -1000.0
type: LocalParameter

381294
units: 304591
value: 0.0
type: LocalParameter

381141
units: 304591
value: 0.0
type: LocalParameter

318788
stoichiometry: 1.0
species: 377811
type: SpeciesReference

380795
units: 304591
value: -1000.0
type: LocalParameter

383041
units: 304591
value: 0.0
type: LocalParameter

380821
units: 304591
value: 0.0
type: LocalParameter

323070
stoichiometry: 1.0
species: 377901
type: SpeciesReference

315122
stoichiometry: 1.0
species: 377853
type: SpeciesReference

382897
units: 304591
value: 0.0
type: LocalParameter

318300
stoichiometry: 1.0
species: 377844
type: SpeciesReference

379206
reversible: false
kinetic law: 317309
notes: GENE_ASSOCIATION: (64078.1) SUBSYSTEM: Transport, Extracellular
fast: false
reactant: 317273
product: 317297
type: Reaction
name: adenosinetransport(1:2Na/Adncotransport)
product: 317285
reactant: 317261

379281
product: 318578
kinetic law: 318603
type: Reaction
notes: GENE_ASSOCIATION: (6546.1) SUBSYSTEM: Transport, Extracellular
reversible: true
name: calcium/sodiumantiporter(1:3),reversible
product: 318591
fast: false
reactant: 318566
reactant: 318554

311856
stoichiometry: 1.0
species: 378239
type: SpeciesReference

379785
kinetic law: 325900
reactant: 325888
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Serineexchange
type: Reaction

314726
stoichiometry: 1.0
species: 377760
type: SpeciesReference

319905
stoichiometry: 1.0
species: 378545
type: SpeciesReference

326274
stoichiometry: 1.0
species: 378161
type: SpeciesReference

317757
stoichiometry: 1.0
species: 377793
type: SpeciesReference

378299
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Oxalate
type: Species

377667
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Acetaldehyde
type: Species

382724
units: 304591
value: 1000.0
type: LocalParameter

311929
stoichiometry: 1.0
species: 377984
type: SpeciesReference

313959
stoichiometry: 1.0
species: 378266
type: SpeciesReference

377808
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Citrate
type: Species

307305
stoichiometry: 1.0
species: 378491
type: SpeciesReference

305122
stoichiometry: 1.0
species: 377580
type: SpeciesReference

318827
stoichiometry: 1.0
species: 377814
type: SpeciesReference

380070
units: 304591
value: 0.0
type: LocalParameter

380668
units: 304591
value: 1000.0
type: LocalParameter

314978
stoichiometry: 1.0
species: 378206
type: SpeciesReference

307450
stoichiometry: 1.0
species: 378212
type: SpeciesReference

382044
units: 304591
value: 1000.0
type: LocalParameter

381971
units: 304591
value: 0.0
type: LocalParameter

381181
units: 304591
value: 0.0
type: LocalParameter

381025
units: 304591
value: 0.0
type: LocalParameter

382614
units: 304591
value: 0.0
type: LocalParameter

382046
units: 304591
value: 0.0
type: LocalParameter

379011
kinetic law: 313392
product: 313380
reversible: false
product: 313368
reactant: 313344
notes: GENE_ASSOCIATION: (4907.1) SUBSYSTEM: Nucleotides
reactant: 313356
name: 5'-nucleotidase(AMP),extracellular
fast: false
type: Reaction

377730
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: AMP
type: Species

304795
stoichiometry: 1.0
species: 378212
type: SpeciesReference

315340
stoichiometry: 1.0
species: 377966
type: SpeciesReference

380071
units: 304591
value: 0.0
type: LocalParameter

310610
stoichiometry: 1.0
species: 378185
type: SpeciesReference

322152
stoichiometry: 1.0
species: 378008
type: SpeciesReference

379704
kinetic law: 325249
reactant: 325237
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

378329
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Phosphoenolpyruvate
type: Species

309548
stoichiometry: 1.0
species: 378002
type: SpeciesReference

378606
kinetic law: 305218
product: 305206
reactant: 305194
notes: GENE_ASSOCIATION: (22934.1) SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: true
name: ribose-5-phosphateisomerase
type: Reaction

316863
stoichiometry: 1.0
species: 378206
type: SpeciesReference

379335
kinetic law: 319652
product: 319640
reactant: 319628
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: Htransporter,endoplasmicreticulum
type: Reaction

382948
units: 304591
value: 13.5135135135135
type: LocalParameter

381238
units: 304591
value: 1000.0
type: LocalParameter

381024
units: 304591
value: 0.0
type: LocalParameter

315134
stoichiometry: 1.0
species: 377993
type: SpeciesReference

381331
units: 304591
value: 0.0
type: LocalParameter

382722
units: 304591
value: -1000.0
type: LocalParameter

377733
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: AMP
type: Species

379014
product: 313465
reversible: false
notes: GENE_ASSOCIATION: (3939.1) or (3945.1 and 3939.1) or (3945.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
type: Reaction
product: 313453
reactant: 313429
fast: false
kinetic law: 313477
reactant: 313417
product: 313441
name: glyoxylateoxidase
reactant: 313404

315789
stoichiometry: 1.0
species: 377850
type: SpeciesReference

324080
stoichiometry: 1.0
species: 378191
type: SpeciesReference

311069
stoichiometry: 1.0
species: 378350
type: SpeciesReference

323260
stoichiometry: 1.0
species: 378212
type: SpeciesReference

380961
units: 304591
value: 0.0
type: LocalParameter

321969
stoichiometry: 1.0
species: 378521
type: SpeciesReference

304903
stoichiometry: 1.0
species: 377769
type: SpeciesReference

382042
units: 304591
value: -1000.0
type: LocalParameter

316707
stoichiometry: 1.0
species: 377850
type: SpeciesReference

312692
stoichiometry: 1.0
species: 378086
type: SpeciesReference

322262
stoichiometry: 1.0
species: 378059
type: SpeciesReference

378609
kinetic law: 305255
product: 305243
reactant: 305231
notes: GENE_ASSOCIATION: (6120.1) or (6120.2) SUBSYSTEM: Pentose Phosphate Pathway
fast: false
reversible: true
name: ribulose5-phosphate3-epimerase
type: Reaction

378326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: phosphatidylinositol (homo sapiens)
type: Species

378479
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphingosine 1-phosphate
type: Species

382949
units: 304591
value: 0.0
type: LocalParameter

309247
stoichiometry: 1.0
species: 378005
type: SpeciesReference

322576
stoichiometry: 1.0
species: 378326
type: SpeciesReference

317213
stoichiometry: 1.0
species: 378545
type: SpeciesReference

320027
stoichiometry: 1.0
species: 378236
type: SpeciesReference

317165
stoichiometry: 1.0
species: 378206
type: SpeciesReference

379782
kinetic law: 325876
reactant: 325864
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Tryptophanexchange
type: Reaction

382616
units: 304591
value: 0.0
type: LocalParameter

318252
stoichiometry: 1.0
species: 378206
type: SpeciesReference

314545
stoichiometry: 1.0
species: 378065
type: SpeciesReference

379227
product: 317721
type: Reaction
product: 317709
reversible: true
kinetic law: 317733
fast: false
reactant: 317685
notes: GENE_ASSOCIATION: (64849.1) or (64849.2) SUBSYSTEM: Transport, Extracellular
reactant: 317697
name: succinatetransportviasodiumsymport

378185
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-Malate
type: Species

310102
stoichiometry: 1.0
species: 378221
type: SpeciesReference

321559
stoichiometry: 1.0
species: 377568
type: SpeciesReference

381758
units: 304591
value: 1000.0
type: LocalParameter

308800
stoichiometry: 1.0
species: 378212
type: SpeciesReference

311348
stoichiometry: 1.0
species: 378251
type: SpeciesReference

379092
reactant: 315002
product: 315038
kinetic law: 315086
fast: false
product: 315062
reversible: false
reactant: 315014
type: Reaction
product: 315050
product: 315074
notes: GENE_ASSOCIATION: (10840.1) SUBSYSTEM: Folate Metabolism
name: formyltetrahydrofolatedehydrogenase
reactant: 315026

380665
units: 304591
value: -1000.0
type: LocalParameter

309428
stoichiometry: 1.0
species: 378077
type: SpeciesReference

378182
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Malate
type: Species

305523
stoichiometry: 1.0
species: 378212
type: SpeciesReference

319049
stoichiometry: 1.0
species: 378041
type: SpeciesReference

324418
stoichiometry: 1.0
species: 378077
type: SpeciesReference

379563
kinetic law: 323488
product: 323476
reactant: 323464
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

382946
units: 304591
value: 0.0
type: LocalParameter

380664
units: 304591
value: 0.0
type: LocalParameter

381185
units: 304591
value: 0.0
type: LocalParameter

379707
kinetic law: 325274
reactant: 325261
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

381021
units: 304591
value: 0.0
type: LocalParameter

378603
kinetic law: 305182
product: 305170
reactant: 305158
notes: GENE_ASSOCIATION: (7167.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: triose-phosphateisomerase
type: Reaction

318361
stoichiometry: 1.0
species: 378164
type: SpeciesReference

380741
units: 304591
value: 0.0
type: LocalParameter

377736
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: AMP
type: Species

377664
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Acetaldehyde
type: Species

382721
units: 304591
value: 0.0
type: LocalParameter

382947
units: 304591
value: 0.0
type: LocalParameter

379098
type: Reaction
reactant: 315158
kinetic law: 315207
fast: false
product: 315195
reactant: 315170
reversible: true
product: 315182
name: L-Serine/Glycinereversibleexchange
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular

382610
units: 304591
value: -1000.0
type: LocalParameter

381235
units: 304591
value: -1000.0
type: LocalParameter

315850
stoichiometry: 1.0
species: 377853
type: SpeciesReference

379788
kinetic law: 325925
reactant: 325913
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Lysineexchange
type: Reaction

382041
units: 304591
value: 0.0
type: LocalParameter

381974
units: 304591
value: 1000.0
type: LocalParameter

313682
stoichiometry: 1.0
species: 377769
type: SpeciesReference

318977
stoichiometry: 1.0
species: 378032
type: SpeciesReference

380931
units: 304591
value: 0.0
type: LocalParameter

320979
stoichiometry: 1.0
species: 378059
type: SpeciesReference

313730
stoichiometry: 1.0
species: 378314
type: SpeciesReference

306554
stoichiometry: 2.0
species: 378077
type: SpeciesReference

382944
units: 304591
value: 13.5135135135135
type: LocalParameter

377661
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetaldehyde
type: Species

381448
units: 304591
value: 1000.0
type: LocalParameter

381335
units: 304591
value: -1000.0
type: LocalParameter

378542
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Xanthine
type: Species

381234
units: 304591
value: 0.0
type: LocalParameter

379095
name: L-cysteine/glycineexchanger
product: 315134
type: Reaction
reactant: 315098
fast: false
reversible: false
notes: GENE_ASSOCIATION: (6520.1) and (23428.1) or (6520.1) and (23428.2) SUBSYSTEM: Transport, Extracellular
product: 315122
reactant: 315110
kinetic law: 315146

378476
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphingosine
type: Species

380965
units: 304591
value: -1000.0
type: LocalParameter

379017
product: 313513
reactant: 313489
product: 313525
reversible: false
type: Reaction
name: Glycolateoxidase,peroxisome
reactant: 313501
fast: false
kinetic law: 313537
notes: GENE_ASSOCIATION: (51179.1) or (51179.2) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism

379560
kinetic law: 323452
product: 323440
reactant: 323428
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

381334
units: 304591
value: 0.0
type: LocalParameter

312607
stoichiometry: 1.0
species: 378212
type: SpeciesReference

320691
stoichiometry: 1.0
species: 378203
type: SpeciesReference

304843
stoichiometry: 1.0
species: 378218
type: SpeciesReference

382945
units: 304591
value: 0.0
type: LocalParameter

379338
kinetic law: 319688
product: 319676
reactant: 319664
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: NADPHtransporter,endoplasmicreticulum
type: Reaction

382612
units: 304591
value: 1000.0
type: LocalParameter

381972
units: 304591
value: -1000.0
type: LocalParameter

380661
units: 304591
value: 0.0
type: LocalParameter

310489
stoichiometry: 5.0
species: 378083
type: SpeciesReference

381184
units: 304591
value: 0.0
type: LocalParameter

380964
units: 304591
value: 0.0
type: LocalParameter

323632
stoichiometry: 1.0
species: 377700
type: SpeciesReference

311227
stoichiometry: 1.0
species: 378194
type: SpeciesReference

380898
units: 304591
value: 1000.0
type: LocalParameter

306372
stoichiometry: 1.0
species: 378029
type: SpeciesReference

380934
units: 304591
value: 0.0
type: LocalParameter

309174
stoichiometry: 1.0
species: 378245
type: SpeciesReference

383281
units: 304591
value: 0.0
type: LocalParameter

383203
units: 304591
value: -1000.0
type: LocalParameter

314327
stoichiometry: 1.0
species: 378338
type: SpeciesReference

320583
stoichiometry: 1.0
species: 377649
type: SpeciesReference

305061
stoichiometry: 1.0
species: 377610
type: SpeciesReference

377739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: arachidonic acid
type: Species

383280
units: 304591
value: 0.0
type: LocalParameter

324018
stoichiometry: 1.0
species: 378107
type: SpeciesReference

382593
units: 304591
value: 0.0
type: LocalParameter

382198
units: 304591
value: 1000.0
type: LocalParameter

313791
stoichiometry: 1.0
species: 378338
type: SpeciesReference

378759
fast: false
reversible: true
kinetic law: 308125
notes: GENE_ASSOCIATION: (50808.1) SUBSYSTEM: Nucleotides
product: 308101
reactant: 308089
name: adentylatekinase(GTP)
reactant: 308077
product: 308113
type: Reaction

380935
units: 304591
value: 0.0
type: LocalParameter

316924
stoichiometry: 1.0
species: 378530
type: SpeciesReference

378320
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)
type: Species

379449
kinetic law: 321656
product: 321643
reactant: 321631
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: NADHtransporter,peroxisome
type: Reaction

378545
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Xanthine
type: Species

382501
units: 304591
value: 0.0
type: LocalParameter

320171
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381078
units: 304591
value: 1000.0
type: LocalParameter

383204
units: 304591
value: 0.0
type: LocalParameter

381445
units: 304591
value: 0.0
type: LocalParameter

379671
kinetic law: 324983
reactant: 324971
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

314399
stoichiometry: 1.0
species: 378479
type: SpeciesReference

383283
units: 304591
value: -1000.0
type: LocalParameter

383200
units: 304591
value: 0.0
type: LocalParameter

310042
stoichiometry: 1.0
species: 377586
type: SpeciesReference

382195
units: 304591
value: 0.0
type: LocalParameter

381074
units: 304591
value: 0.0
type: LocalParameter

381125
units: 304591
value: -1000.0
type: LocalParameter

381188
units: 304591
value: 1000.0
type: LocalParameter

383201
units: 304591
value: 0.0
type: LocalParameter

326057
stoichiometry: 1.0
species: 377697
type: SpeciesReference

378699
name: Diphosphoglyceratephosphatase
fast: false
product: 307075
type: Reaction
reversible: false
reactant: 307051
kinetic law: 307099
reactant: 307063
notes: GENE_ASSOCIATION: (5223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 307087

383059
units: 304591
value: 0.0
type: LocalParameter

381444
units: 304591
value: 0.0
type: LocalParameter

312945
stoichiometry: 1.0
species: 377874
type: SpeciesReference

310078
stoichiometry: 1.0
species: 377889
type: SpeciesReference

380895
units: 304591
value: -1000.0
type: LocalParameter

382591
units: 304591
value: 1000.0
type: LocalParameter

383282
units: 304591
value: 0.0
type: LocalParameter

378548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Xylulose 1-phosphate
type: Species

382196
units: 304591
value: -1000.0
type: LocalParameter

381075
units: 304591
value: -1000.0
type: LocalParameter

380968
units: 304591
value: 1000.0
type: LocalParameter

310332
stoichiometry: 1.0
species: 377923
type: SpeciesReference

383202
units: 304591
value: 0.0
type: LocalParameter

381124
units: 304591
value: 0.0
type: LocalParameter

382503
units: 304591
value: 0.0
type: LocalParameter

378290
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Oxaloacetate
type: Species

381338
units: 304591
value: 1000.0
type: LocalParameter

308161
stoichiometry: 1.0
species: 377993
type: SpeciesReference

318566
stoichiometry: 3.0
species: 378209
type: SpeciesReference

380938
units: 304591
value: 1000.0
type: LocalParameter

380511
units: 304591
value: 0.0
type: LocalParameter

380388
units: 304591
value: 1000.0
type: LocalParameter

380074
units: 304591
value: 1000.0
type: LocalParameter

383056
units: 304591
value: 13.5135135135135
type: LocalParameter

380894
units: 304591
value: 0.0
type: LocalParameter

378693
kinetic law: 306978
product: 306966
reactant: 306954
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: CO2transport(diffusion),mitochondrial
type: Reaction

318144
stoichiometry: 1.0
species: 378149
type: SpeciesReference

320244
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382833
units: 304591
value: 1.0
type: LocalParameter

311118
stoichiometry: 1.0
species: 378092
type: SpeciesReference

382049
units: 304591
value: -1000.0
type: LocalParameter

377917
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ferricytochrome c
type: Species

379446
kinetic law: 321619
product: 321607
reactant: 321595
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: pristperoxisomaltransport
type: Reaction

322853
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382504
units: 304591
value: -1000.0
type: LocalParameter

314617
stoichiometry: 1.0
species: 377598
type: SpeciesReference

304687
stoichiometry: 1.0
species: 377871
type: SpeciesReference

382228
units: 304591
value: 0.0
type: LocalParameter

317321
stoichiometry: 1.0
species: 378137
type: SpeciesReference

320619
stoichiometry: 1.0
species: 378059
type: SpeciesReference

323946
stoichiometry: 1.0
species: 377996
type: SpeciesReference

306627
stoichiometry: 1.0
species: 377883
type: SpeciesReference

383057
units: 304591
value: 0.0
type: LocalParameter

325985
stoichiometry: 1.0
species: 377853
type: SpeciesReference

382834
units: 304591
value: 0.0
type: LocalParameter

317080
stoichiometry: 1.0
species: 378209
type: SpeciesReference

378296
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: 4-oxo-retonoic acid
type: Species

378963
product: 312352
reactant: 312340
reversible: true
kinetic law: 312389
notes: GENE_ASSOCIATION: (3418.1) SUBSYSTEM: Citric Acid Cycle
reactant: 312328
name: Isocitratedehydrogenase(NADP+)
fast: false
product: 312364
type: Reaction
product: 312376

379116
name: D-alanine/glycinereversibleexchange
reactant: 315523
fast: false
reactant: 315535
reversible: true
kinetic law: 315572
product: 315559
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
product: 315547

381441
units: 304591
value: 0.0
type: LocalParameter

383058
units: 304591
value: 0.0
type: LocalParameter

320389
stoichiometry: 1.0
species: 378077
type: SpeciesReference

308053
stoichiometry: 2.0
species: 377703
type: SpeciesReference

382598
units: 304591
value: 1000.0
type: LocalParameter

309658
stoichiometry: 1.0
species: 378278
type: SpeciesReference

312583
stoichiometry: 1.0
species: 378554
type: SpeciesReference

310937
stoichiometry: 1.0
species: 378272
type: SpeciesReference

308958
stoichiometry: 1.0
species: 377927
type: SpeciesReference

320316
stoichiometry: 1.0
species: 378077
type: SpeciesReference

383054
units: 304591
value: 0.0
type: LocalParameter

382506
units: 304591
value: 1000.0
type: LocalParameter

378293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 4-oxo-retonoic acid
type: Species

378960
fast: false
reactant: 312268
name: inorganicdiphosphatase,endoplasmicreticulum
reversible: false
type: Reaction
kinetic law: 312316
product: 312292
product: 312304
notes: GENE_ASSOCIATION: (92579.1) SUBSYSTEM: Miscellaneous
reactant: 312280

380077
units: 304591
value: 0.0
type: LocalParameter

382831
units: 304591
value: 0.0
type: LocalParameter

379119
product: 315608
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
type: Reaction
reversible: true
reactant: 315584
fast: false
reactant: 315596
product: 315620
name: L-alanine/glutaminereversibleexchange
kinetic law: 315632

316658
stoichiometry: 1.0
species: 378335
type: SpeciesReference

382226
units: 304591
value: 1000.0
type: LocalParameter

323428
stoichiometry: 1.0
species: 378395
type: SpeciesReference

378188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Methionine
type: Species

378323
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: phosphatidylinositol (homo sapiens)
type: Species

317273
stoichiometry: 2.0
species: 378209
type: SpeciesReference

381071
units: 304591
value: 0.0
type: LocalParameter

382595
units: 304591
value: 0.0
type: LocalParameter

380891
units: 304591
value: 0.0
type: LocalParameter

311179
stoichiometry: 3.0
species: 378206
type: SpeciesReference

383055
units: 304591
value: 0.0
type: LocalParameter

305413
stoichiometry: 1.0
species: 377905
type: SpeciesReference

379443
kinetic law: 321583
product: 321571
reactant: 321559
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 13-cis-4-oxo-retinoicacidtransport,Nuclear
type: Reaction

378696
reversible: true
product: 307014
notes: GENE_ASSOCIATION: (5250.4) or (5250.1) or (5250.3) or (5250.2) SUBSYSTEM: Transport, Mitochondrial
product: 307027
fast: false
reactant: 307002
reactant: 306990
type: Reaction
kinetic law: 307039
name: phosphatetransporter,mitochondrial

382596
units: 304591
value: 0.0
type: LocalParameter

315026
stoichiometry: 1.0
species: 378227
type: SpeciesReference

381128
units: 304591
value: 1000.0
type: LocalParameter

317649
stoichiometry: 2.0
species: 378206
type: SpeciesReference

382048
units: 304591
value: 0.0
type: LocalParameter

321487
stoichiometry: 1.0
species: 378293
type: SpeciesReference

378750
kinetic law: 307980
product: 307968
reactant: 307956
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: ethanolreversibletransport
type: Reaction

316405
stoichiometry: 1.0
species: 377799
type: SpeciesReference

383289
units: 304591
value: 0.0
type: LocalParameter

382838
units: 304591
value: 0.0
type: LocalParameter

382235
units: 304591
value: 0.0
type: LocalParameter

381558
units: 304591
value: 1000.0
type: LocalParameter

378074
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: H2O
type: Species

380514
units: 304591
value: 0.0
type: LocalParameter

383053
units: 304591
value: 0.0
type: LocalParameter

379917
units: 304591
value: 0.0
type: LocalParameter

382375
units: 304591
value: 0.0
type: LocalParameter

383288
units: 304591
value: 0.0
type: LocalParameter

380441
units: 304591
value: 0.0
type: LocalParameter

382480
units: 304591
value: 0.0
type: LocalParameter

379855
kinetic law: 326479
reactant: 326467
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Asparagineexchange
type: Reaction

380395
units: 304591
value: -1000.0
type: LocalParameter

379668
kinetic law: 324959
reactant: 324947
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382377
units: 304591
value: 0.0
type: LocalParameter

379125
reactant: 315704
name: L-threonine/glycinereversibleexchange
product: 315728
reversible: true
kinetic law: 315752
fast: false
reactant: 315716
type: Reaction
product: 315740
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular

382508
units: 304591
value: 0.0
type: LocalParameter

306590
stoichiometry: 1.0
species: 377769
type: SpeciesReference

381664
units: 304591
value: 0.0
type: LocalParameter

378777
product: 308449
product: 308437
name: L-4-hydroxyglutamatesemialdehydedehydrogenase,mitochondrial
fast: false
reactant: 308401
notes: GENE_ASSOCIATION: (8659.1) or (8659.2) SUBSYSTEM: Arginine and Proline Metabolism
reactant: 308413
product: 308461
kinetic law: 308473
type: Reaction
reactant: 308425
reversible: true

305632
stoichiometry: 2.0
species: 378077
type: SpeciesReference

383052
units: 304591
value: 13.5135135135135
type: LocalParameter

380515
units: 304591
value: 0.0
type: LocalParameter

325383
stoichiometry: 1.0
species: 377571
type: SpeciesReference

323740
stoichiometry: 1.0
species: 378521
type: SpeciesReference

307872
stoichiometry: 1.0
species: 378434
type: SpeciesReference

324164
stoichiometry: 1.0
species: 378458
type: SpeciesReference

324683
stoichiometry: 1.0
species: 378158
type: SpeciesReference

382233
units: 304591
value: 1000.0
type: LocalParameter

379665
kinetic law: 324935
reactant: 324923
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382836
units: 304591
value: 13.5135135135135
type: LocalParameter

380394
units: 304591
value: 0.0
type: LocalParameter

382588
units: 304591
value: 0.0
type: LocalParameter

312728
stoichiometry: 1.0
species: 378233
type: SpeciesReference

378774
kinetic law: 308389
product: 308377
reactant: 308365
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: L-carnitinereversibletransport
type: Reaction

378966
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
fast: false
type: Reaction
product: 312437
name: L-gulonate3-dehydrogenase
reversible: true
product: 312449
reactant: 312413
reactant: 312401
product: 312425
kinetic law: 312461

383051
units: 304591
value: 0.0
type: LocalParameter

307679
stoichiometry: 1.0
species: 377658
type: SpeciesReference

381660
units: 304591
value: 1000.0
type: LocalParameter

313610
stoichiometry: 1.0
species: 377769
type: SpeciesReference

311796
stoichiometry: 1.0
species: 378152
type: SpeciesReference

310550
stoichiometry: 1.0
species: 378413
type: SpeciesReference

382373
units: 304591
value: 1000.0
type: LocalParameter

306288
stoichiometry: 1.0
species: 378338
type: SpeciesReference

316513
stoichiometry: 1.0
species: 378161
type: SpeciesReference

378753
kinetic law: 308017
product: 308005
reactant: 307992
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: acetaldehydereversibletransport
type: Reaction

382589
units: 304591
value: 0.0
type: LocalParameter

377927
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Fructose
type: Species

378071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: H2O
type: Species

380299
units: 304591
value: -1000.0
type: LocalParameter

379452
kinetic law: 321692
product: 321680
reactant: 321668
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: NADtransporter,peroxisome
type: Reaction

381662
units: 304591
value: 0.0
type: LocalParameter

322937
stoichiometry: 1.0
species: 378200
type: SpeciesReference

324899
stoichiometry: 1.0
species: 377748
type: SpeciesReference

383050
units: 304591
value: 0.0
type: LocalParameter

313585
stoichiometry: 1.0
species: 378218
type: SpeciesReference

380928
units: 304591
value: 1000.0
type: LocalParameter

379858
kinetic law: 326503
reactant: 326491
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Arginineexchange
type: Reaction

310260
stoichiometry: 1.0
species: 378383
type: SpeciesReference

311700
stoichiometry: 1.0
species: 378212
type: SpeciesReference

312328
stoichiometry: 1.0
species: 378119
type: SpeciesReference

319303
stoichiometry: 3.0
species: 378206
type: SpeciesReference

315402
stoichiometry: 1.0
species: 377727
type: SpeciesReference

381134
units: 304591
value: 0.0
type: LocalParameter

304615
exponent: -1.0
scale: 0
multipler: 2.77777777777778E-4
kind: SECOND
type: SBMLUnit

379852
kinetic law: 326455
reactant: 326443
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Aspartateexchange
type: Reaction

383284
units: 304591
value: 0.0
type: LocalParameter

382230
units: 304591
value: 0.0
type: LocalParameter

312122
stoichiometry: 1.0
species: 378389
type: SpeciesReference

378819
kinetic law: 309198
product: 309186
reactant: 309174
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: ammoniaperoxisomaltransport
type: Reaction

380180
units: 304591
value: 0.0
type: LocalParameter

380518
units: 304591
value: 1000.0
type: LocalParameter

378077
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: H+
type: Species

314187
stoichiometry: 1.0
species: 377628
type: SpeciesReference

381135
units: 304591
value: -1000.0
type: LocalParameter

319628
stoichiometry: 1.0
species: 378077
type: SpeciesReference

380391
units: 304591
value: 0.0
type: LocalParameter

323208
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382231
units: 304591
value: 0.0
type: LocalParameter

306408
stoichiometry: 1.0
species: 378338
type: SpeciesReference

383285
units: 304591
value: 0.0
type: LocalParameter

382193
units: 304591
value: 0.0
type: LocalParameter

322636
stoichiometry: 1.0
species: 378347
type: SpeciesReference

377920
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Ferrocytochrome C
type: Species

381827
units: 304591
value: 1000.0
type: LocalParameter

383120
units: 304591
value: 13.5135135135135
type: LocalParameter

305280
stoichiometry: 1.0
species: 378443
type: SpeciesReference

378756
kinetic law: 308065
product: 308053
reactant: 308041
reactant: 308029
notes: GENE_ASSOCIATION: (205.1) or (205.3) or (205.2) SUBSYSTEM: Nucleotides
fast: false
reversible: true
name: adenylatekinase,mitochondrial
type: Reaction

382378
units: 304591
value: 0.0
type: LocalParameter

317867
stoichiometry: 1.0
species: 377775
type: SpeciesReference

379122
reactant: 315644
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
reactant: 315656
product: 315680
product: 315668
reversible: true
fast: false
name: L-threonine/glycinereversibleexchange
type: Reaction
kinetic law: 315692

377811
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Chloride
type: Species

315499
stoichiometry: 1.0
species: 377969
type: SpeciesReference

307147
stoichiometry: 1.0
species: 377802
type: SpeciesReference

381131
units: 304591
value: 0.0
type: LocalParameter

324971
stoichiometry: 1.0
species: 377802
type: SpeciesReference

383286
units: 304591
value: 0.0
type: LocalParameter

307027
stoichiometry: 1.0
species: 378344
type: SpeciesReference

383121
units: 304591
value: 0.0
type: LocalParameter

316489
stoichiometry: 1.0
species: 378338
type: SpeciesReference

379662
kinetic law: 324911
reactant: 324899
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

377923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Formate
type: Species

383287
units: 304591
value: -1000.0
type: LocalParameter

310719
stoichiometry: 2.0
species: 377920
type: SpeciesReference

326659
stoichiometry: 1.0
species: 378437
type: SpeciesReference

313368
stoichiometry: 1.0
species: 377697
type: SpeciesReference

378816
kinetic law: 309162
product: 309150
reactant: 309138
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: H2Oendoplasmicreticulumtransport
type: Reaction

325043
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380181
units: 304591
value: -1000.0
type: LocalParameter

383122
units: 304591
value: 0.0
type: LocalParameter

378969
name: dehydro-L-gulonatedecarboxylase
reactant: 312485
type: Reaction
reactant: 312473
reversible: true
kinetic law: 312521
fast: false
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
product: 312497
product: 312509

382191
units: 304591
value: 1000.0
type: LocalParameter

325503
stoichiometry: 1.0
species: 378095
type: SpeciesReference

381829
units: 304591
value: 0.0
type: LocalParameter

380184
units: 304591
value: 1000.0
type: LocalParameter

381978
units: 304591
value: 0.0
type: LocalParameter

325864
stoichiometry: 1.0
species: 378509
type: SpeciesReference

311568
stoichiometry: 1.0
species: 377817
type: SpeciesReference

321015
stoichiometry: 2.0
species: 378077
type: SpeciesReference

381824
units: 304591
value: 0.0
type: LocalParameter

380744
units: 304591
value: 0.0
type: LocalParameter

383123
units: 304591
value: 0.0
type: LocalParameter

317381
stoichiometry: 1.0
species: 377954
type: SpeciesReference

315559
stoichiometry: 1.0
species: 377996
type: SpeciesReference

382489
units: 304591
value: 0.0
type: LocalParameter

379554
kinetic law: 323380
product: 323368
reactant: 323356
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: hydrogenperoxidemitochondrialtransport
type: Reaction

378485
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Succinate
type: Species

383124
units: 304591
value: 13.5135135135135
type: LocalParameter

382943
units: 304591
value: 0.0
type: LocalParameter

382796
units: 304591
value: 0.0
type: LocalParameter

381979
units: 304591
value: 0.0
type: LocalParameter

380745
units: 304591
value: 0.0
type: LocalParameter

323320
stoichiometry: 1.0
species: 378281
type: SpeciesReference

381753
units: 304591
value: 0.0
type: LocalParameter

312014
stoichiometry: 1.0
species: 377562
type: SpeciesReference

309756
stoichiometry: 1.0
species: 377817
type: SpeciesReference

381244
units: 304591
value: 0.0
type: LocalParameter

304723
stoichiometry: 1.0
species: 377914
type: SpeciesReference

317975
stoichiometry: 1.0
species: 377739
type: SpeciesReference

379230
kinetic law: 317769
product: 317757
reactant: 317745
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: Cholineuniport
type: Reaction

382942
units: 304591
value: 0.0
type: LocalParameter

379008
kinetic law: 313332
product: 313320
reactant: 313308
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: deoxyinosinetransportviadiffusion
type: Reaction

383125
units: 304591
value: 0.0
type: LocalParameter

379341
kinetic law: 319725
product: 319712
reactant: 319700
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: NADPtransporter,endoplasmicreticulum
type: Reaction

380200
units: 304591
value: 0.0
type: LocalParameter

381551
units: 304591
value: 0.0
type: LocalParameter

378813
kinetic law: 309126
product: 309114
reactant: 309102
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: O2transport,endoplasmicreticulum
type: Reaction

381976
units: 304591
value: 0.0
type: LocalParameter

308982
stoichiometry: 1.0
species: 378218
type: SpeciesReference

382487
units: 304591
value: 0.0
type: LocalParameter

381669
units: 304591
value: 0.0
type: LocalParameter

379910
units: 304591
value: 0.0
type: LocalParameter

380187
units: 304591
value: 0.0
type: LocalParameter

382794
units: 304591
value: 1000.0
type: LocalParameter

314031
stoichiometry: 1.0
species: 378314
type: SpeciesReference

383126
units: 304591
value: 0.0
type: LocalParameter

382941
units: 304591
value: 0.0
type: LocalParameter

321776
stoichiometry: 1.0
species: 378389
type: SpeciesReference

381825
units: 304591
value: -1000.0
type: LocalParameter

380448
units: 304591
value: 1000.0
type: LocalParameter

310828
stoichiometry: 3.0
species: 378083
type: SpeciesReference

307257
stoichiometry: 1.0
species: 378059
type: SpeciesReference

381751
units: 304591
value: 1000.0
type: LocalParameter

381241
units: 304591
value: 0.0
type: LocalParameter

377892
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Erythrose 4-phosphate
type: Species

378600
reactant: 305097
name: phosphoglyceratekinase
notes: GENE_ASSOCIATION: (5230.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 305122
fast: false
type: Reaction
reactant: 305109
kinetic law: 305146
product: 305134
reversible: true

321111
stoichiometry: 1.0
species: 378236
type: SpeciesReference

322793
stoichiometry: 1.0
species: 377769
type: SpeciesReference

318048
stoichiometry: 1.0
species: 378260
type: SpeciesReference

377814
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Chloride
type: Species

379911
units: 304591
value: -1000.0
type: LocalParameter

315098
stoichiometry: 1.0
species: 377850
type: SpeciesReference

382940
units: 304591
value: 13.5135135135135
type: LocalParameter

383127
units: 304591
value: -1000.0
type: LocalParameter

316598
stoichiometry: 1.0
species: 378536
type: SpeciesReference

380748
units: 304591
value: 1000.0
type: LocalParameter

381820
units: 304591
value: 1000.0
type: LocalParameter

380445
units: 304591
value: -1000.0
type: LocalParameter

381756
units: 304591
value: -1000.0
type: LocalParameter

382371
units: 304591
value: 0.0
type: LocalParameter

379233
product: 317818
reactant: 317793
reactant: 317781
name: L-carnitineinwardtransportbyNa+symport
kinetic law: 317831
reversible: false
fast: false
product: 317806
type: Reaction
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular

381667
units: 304591
value: 1000.0
type: LocalParameter

383128
units: 304591
value: 13.5135135135135
type: LocalParameter

378810
kinetic law: 309090
product: 309078
reactant: 309066
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: H2Otransport,peroxisomal
type: Reaction

381554
units: 304591
value: 0.0
type: LocalParameter

379344
kinetic law: 319761
product: 319749
reactant: 319737
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: Diphosphatetransporter,endoplasmicreticulum
type: Reaction

377817
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: CO2
type: Species

382729
units: 304591
value: -1000.0
type: LocalParameter

306072
stoichiometry: 1.0
species: 377730
type: SpeciesReference

382485
units: 304591
value: 1000.0
type: LocalParameter

308401
stoichiometry: 1.0
species: 377625
type: SpeciesReference

377898
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Ethanol
type: Species

379914
units: 304591
value: 1000.0
type: LocalParameter

318905
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382617
units: 304591
value: -1000.0
type: LocalParameter

378482
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphingosine 1-phosphate
type: Species

381555
units: 304591
value: -1000.0
type: LocalParameter

310791
stoichiometry: 1.0
species: 378344
type: SpeciesReference

383129
units: 304591
value: 0.0
type: LocalParameter

381018
units: 304591
value: 0.0
type: LocalParameter

382728
units: 304591
value: 0.0
type: LocalParameter

319279
stoichiometry: 1.0
species: 378059
type: SpeciesReference

307522
stoichiometry: 1.0
species: 378077
type: SpeciesReference

377895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Ethanol
type: Species

313501
stoichiometry: 1.0
species: 378278
type: SpeciesReference

381822
units: 304591
value: 0.0
type: LocalParameter

382482
units: 304591
value: 0.0
type: LocalParameter

307389
stoichiometry: 2.0
species: 378077
type: SpeciesReference

312098
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382798
units: 304591
value: 0.0
type: LocalParameter

381665
units: 304591
value: 0.0
type: LocalParameter

381015
units: 304591
value: -1000.0
type: LocalParameter

304579
exponent: -1.0
scale: 0
multipler: 2.77777777777778E-4
kind: SECOND
type: SBMLUnit

313150
stoichiometry: 1.0
species: 378236
type: SpeciesReference

379701
kinetic law: 325225
reactant: 325212
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382370
units: 304591
value: 0.0
type: LocalParameter

306132
stoichiometry: 2.0
species: 377700
type: SpeciesReference

382483
units: 304591
value: -1000.0
type: LocalParameter

324490
stoichiometry: 1.0
species: 378515
type: SpeciesReference

381755
units: 304591
value: 0.0
type: LocalParameter

380444
units: 304591
value: 0.0
type: LocalParameter

321848
stoichiometry: 1.0
species: 378071
type: SpeciesReference

382799
units: 304591
value: -1000.0
type: LocalParameter

382619
units: 304591
value: 1000.0
type: LocalParameter

379236
reversible: true
reactant: 317855
type: Reaction
notes: GENE_ASSOCIATION: (28234.1) SUBSYSTEM: Transport, Extracellular
reactant: 317843
name: bilirubinmonoglucuronidetransportviabicarbonatecountertransport
kinetic law: 317891
product: 317879
product: 317867
fast: false

378771
reversible: true
notes: GENE_ASSOCIATION: (79751.1) SUBSYSTEM: Transport, Mitochondrial
product: 308341
product: 308329
reactant: 308317
kinetic law: 308353
fast: false
name: L-glutamatereversibletransportviaprotonsymport,mitochondrial
type: Reaction
reactant: 308305

379791
kinetic law: 325949
reactant: 325937
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Glycineexchange
type: Reaction

379557
kinetic law: 323416
product: 323404
reactant: 323392
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: hydrogenperoxidetransportviadiffusion
type: Reaction

382698
units: 304591
value: 0.0
type: LocalParameter

382726
units: 304591
value: 0.0
type: LocalParameter

315777
stoichiometry: 1.0
species: 377966
type: SpeciesReference

326346
stoichiometry: 1.0
species: 378125
type: SpeciesReference

306868
stoichiometry: 1.0
species: 378065
type: SpeciesReference

377721
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Alanine
type: Species

382710
units: 304591
value: 1000.0
type: LocalParameter

324092
stoichiometry: 1.0
species: 378209
type: SpeciesReference

379002
kinetic law: 313259
product: 313247
reactant: 313234
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: deoxyadenosinetransportviadiffusion
type: Reaction

379323
kinetic law: 319412
product: 319400
reactant: 319388
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: D-glucurono-6,3-lactonetransport,endoplasmicreticulum
type: Reaction

316031
stoichiometry: 1.0
species: 377978
type: SpeciesReference

382936
units: 304591
value: 13.5135135135135
type: LocalParameter

382603
units: 304591
value: -1000.0
type: LocalParameter

320014
stoichiometry: 1.0
species: 378200
type: SpeciesReference

304915
stoichiometry: 1.0
species: 378404
type: SpeciesReference

381981
units: 304591
value: 1000.0
type: LocalParameter

312231
stoichiometry: 1.0
species: 378350
type: SpeciesReference

381191
units: 304591
value: 0.0
type: LocalParameter

381011
units: 304591
value: 0.0
type: LocalParameter

380678
units: 304591
value: 1000.0
type: LocalParameter

308751
stoichiometry: 1.0
species: 378101
type: SpeciesReference

322274
stoichiometry: 1.0
species: 378227
type: SpeciesReference

324224
stoichiometry: 1.0
species: 378575
type: SpeciesReference

382030
units: 304591
value: 1000.0
type: LocalParameter

382693
units: 304591
value: 0.0
type: LocalParameter

381902
units: 304591
value: 0.0
type: LocalParameter

380084
units: 304591
value: 1000.0
type: LocalParameter

316272
stoichiometry: 1.0
species: 377637
type: SpeciesReference

314533
stoichiometry: 1.0
species: 377583
type: SpeciesReference

318264
stoichiometry: 1.0
species: 377709
type: SpeciesReference

379215
type: Reaction
reactant: 317453
name: inositoltransportviasodiumsymport
reactant: 317441
product: 317465
notes: GENE_ASSOCIATION: (6526.1) SUBSYSTEM: Transport, Extracellular
reversible: true
kinetic law: 317489
fast: false
product: 317477

378173
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Lysine
type: Species

378338
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Phosphate
type: Species

317201
stoichiometry: 1.0
species: 378278
type: SpeciesReference

378551
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Xylulose 5-phosphate
type: Species

381225
units: 304591
value: 0.0
type: LocalParameter

322564
stoichiometry: 1.0
species: 378323
type: SpeciesReference

382937
units: 304591
value: 0.0
type: LocalParameter

379794
kinetic law: 325973
reactant: 325961
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Deoxyadenosineexchange
type: Reaction

309235
stoichiometry: 1.0
species: 378236
type: SpeciesReference

305510
stoichiometry: 1.0
species: 378146
type: SpeciesReference

379080
name: L-leucinetransportinviasodiumsymport
product: 314810
product: 314822
kinetic law: 314834
reactant: 314798
fast: false
type: Reaction
notes: GENE_ASSOCIATION: (84889.1) or (6520.1) SUBSYSTEM: Transport, Extracellular
reversible: false
reactant: 314786

308812
stoichiometry: 1.0
species: 378005
type: SpeciesReference

305268
stoichiometry: 1.0
species: 377933
type: SpeciesReference

381341
units: 304591
value: 0.0
type: LocalParameter

377655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Acetate
type: Species

382712
units: 304591
value: 0.0
type: LocalParameter

381345
units: 304591
value: -1000.0
type: LocalParameter

313947
stoichiometry: 1.0
species: 378128
type: SpeciesReference

381228
units: 304591
value: 1000.0
type: LocalParameter

381014
units: 304591
value: 0.0
type: LocalParameter

311868
stoichiometry: 1.0
species: 377975
type: SpeciesReference

379797
kinetic law: 325997
reactant: 325985
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Cysteineexchange
type: Reaction

314738
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382696
units: 304591
value: 0.0
type: LocalParameter

378287
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Superoxide anion
type: Species

382938
units: 304591
value: 0.0
type: LocalParameter

314966
stoichiometry: 1.0
species: 378104
type: SpeciesReference

382032
units: 304591
value: 0.0
type: LocalParameter

381983
units: 304591
value: 0.0
type: LocalParameter

380951
units: 304591
value: 0.0
type: LocalParameter

324538
stoichiometry: 1.0
species: 378500
type: SpeciesReference

381344
units: 304591
value: 0.0
type: LocalParameter

382602
units: 304591
value: 0.0
type: LocalParameter

382939
units: 304591
value: 0.0
type: LocalParameter

314250
stoichiometry: 1.0
species: 378077
type: SpeciesReference

379716
kinetic law: 325347
reactant: 325335
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 4hydroxyretinoicaciddemand
type: Reaction

382694
units: 304591
value: -1000.0
type: LocalParameter

381194
units: 304591
value: 0.0
type: LocalParameter

309536
stoichiometry: 1.0
species: 377871
type: SpeciesReference

381901
units: 304591
value: 0.0
type: LocalParameter

378554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Xylitol
type: Species

382468
units: 304591
value: 0.0
type: LocalParameter

378488
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Succinate
type: Species

378206
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sodium
type: Species

379083
kinetic law: 314870
product: 314858
reactant: 314846
notes: GENE_ASSOCIATION: (84889.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
type: Reaction

382932
units: 304591
value: 13.5135135135135
type: LocalParameter

313839
stoichiometry: 1.0
species: 378014
type: SpeciesReference

380080
units: 304591
value: 0.0
type: LocalParameter

381906
units: 304591
value: 0.0
type: LocalParameter

380674
units: 304591
value: 0.0
type: LocalParameter

381985
units: 304591
value: 0.0
type: LocalParameter

381195
units: 304591
value: 0.0
type: LocalParameter

381221
units: 304591
value: 0.0
type: LocalParameter

382600
units: 304591
value: 0.0
type: LocalParameter

379326
notes: GENE_ASSOCIATION: (51179.2) or (51179.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
fast: false
name: glyoxylateoxidase,peroxisomal
reactant: 319424
product: 319484
kinetic law: 319496
reactant: 319448
reactant: 319436
product: 319472
reversible: false
type: Reaction
product: 319460

305486
stoichiometry: 1.0
species: 378218
type: SpeciesReference

318374
stoichiometry: 1.0
species: 378206
type: SpeciesReference

382933
units: 304591
value: 0.0
type: LocalParameter

313017
stoichiometry: 1.0
species: 377999
type: SpeciesReference

379005
kinetic law: 313296
product: 313283
reactant: 313271
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: deoyguanosinetransportviadiffusion
type: Reaction

380081
units: 304591
value: 0.0
type: LocalParameter

311215
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380941
units: 304591
value: 0.0
type: LocalParameter

323644
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382934
units: 304591
value: 0.0
type: LocalParameter

381224
units: 304591
value: 0.0
type: LocalParameter

379218
name: choline,sodiumcotransport
reversible: true
reactant: 317501
reactant: 317513
kinetic law: 317551
product: 317525
type: Reaction
product: 317538
fast: false
notes: GENE_ASSOCIATION: (60482.1) SUBSYSTEM: Transport, Extracellular

308281
stoichiometry: 1.0
species: 378383
type: SpeciesReference

378170
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: (R)-S-Lactoylglutathione
type: Species

379551
kinetic law: 323344
product: 323332
reactant: 323320
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
type: Reaction

381904
units: 304591
value: 1000.0
type: LocalParameter

377724
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Alanine
type: Species

380955
units: 304591
value: -1000.0
type: LocalParameter

382691
units: 304591
value: 0.0
type: LocalParameter

379719
kinetic law: 325371
reactant: 325359
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 13-cis-retinoatedemand
type: Reaction

378209
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Sodium
type: Species

316308
stoichiometry: 1.0
species: 378458
type: SpeciesReference

382935
units: 304591
value: 0.0
type: LocalParameter

379086
product: 314918
name: L-methioninetransportinviasodiumsymport
reactant: 314894
fast: false
reactant: 314882
notes: GENE_ASSOCIATION: (54407.1) or (6584.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 314930
reversible: false
type: Reaction
product: 314906

382469
units: 304591
value: -1000.0
type: LocalParameter

381348
units: 304591
value: 1000.0
type: LocalParameter

377652
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetate
type: Species

318989
stoichiometry: 1.0
species: 378035
type: SpeciesReference

311640
stoichiometry: 1.0
species: 378200
type: SpeciesReference

318615
stoichiometry: 2.0
species: 377814
type: SpeciesReference

306566
stoichiometry: 1.0
species: 378257
type: SpeciesReference

380675
units: 304591
value: -1000.0
type: LocalParameter

381986
units: 304591
value: -1000.0
type: LocalParameter

381198
units: 304591
value: 1000.0
type: LocalParameter

380954
units: 304591
value: 0.0
type: LocalParameter

313694
stoichiometry: 1.0
species: 378323
type: SpeciesReference

379329
reactant: 319508
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: (3795.1) or (3795.2) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
reactant: 319520
product: 319544
name: ketohexokinase(D-xylulose)
kinetic law: 319568
fast: false
product: 319556
product: 319532

311580
stoichiometry: 1.0
species: 378512
type: SpeciesReference

380378
units: 304591
value: 1000.0
type: LocalParameter

380944
units: 304591
value: 0.0
type: LocalParameter

383271
units: 304591
value: -1000.0
type: LocalParameter

305329
stoichiometry: 1.0
species: 378419
type: SpeciesReference

310054
stoichiometry: 2.0
species: 378065
type: SpeciesReference

320859
stoichiometry: 1.0
species: 377769
type: SpeciesReference

323536
stoichiometry: 1.0
species: 378569
type: SpeciesReference

380884
units: 304591
value: 0.0
type: LocalParameter

312957
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382039
units: 304591
value: 0.0
type: LocalParameter

382359
units: 304591
value: 1000.0
type: LocalParameter

305596
stoichiometry: 1.0
species: 378059
type: SpeciesReference

383270
units: 304591
value: 0.0
type: LocalParameter

380945
units: 304591
value: 0.0
type: LocalParameter

382184
units: 304591
value: 1000.0
type: LocalParameter

310320
stoichiometry: 1.0
species: 377769
type: SpeciesReference

311106
stoichiometry: 1.0
species: 378077
type: SpeciesReference

310066
stoichiometry: 1.0
species: 378215
type: SpeciesReference

381455
units: 304591
value: 0.0
type: LocalParameter

308173
stoichiometry: 1.0
species: 378059
type: SpeciesReference

381088
units: 304591
value: 1000.0
type: LocalParameter

382582
units: 304591
value: -1000.0
type: LocalParameter

318482
stoichiometry: 1.0
species: 378518
type: SpeciesReference

381458
units: 304591
value: 1000.0
type: LocalParameter

314315
stoichiometry: 1.0
species: 378320
type: SpeciesReference

306360
stoichiometry: 1.0
species: 377604
type: SpeciesReference

314460
stoichiometry: 1.0
species: 378476
type: SpeciesReference

381115
units: 304591
value: 0.0
type: LocalParameter

324006
stoichiometry: 1.0
species: 378095
type: SpeciesReference

382581
units: 304591
value: 0.0
type: LocalParameter

380958
units: 304591
value: 1000.0
type: LocalParameter

378747
product: 307920
kinetic law: 307944
product: 307932
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
reactant: 307908
reactant: 307896
type: Reaction
reversible: true
name: acetatereversibletransportviaprotonsymport
fast: false

380671
units: 304591
value: 0.0
type: LocalParameter

382186
units: 304591
value: 0.0
type: LocalParameter

380885
units: 304591
value: 0.0
type: LocalParameter

380308
units: 304591
value: 1000.0
type: LocalParameter

377727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Alanine
type: Species

315995
stoichiometry: 1.0
species: 378080
type: SpeciesReference

317538
stoichiometry: 1.0
species: 378206
type: SpeciesReference

378332
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Phenylalanine
type: Species

379437
kinetic law: 321511
product: 321499
reactant: 321487
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: true
name: 13-cis-4-oxo-retinoicacidisomerase
type: Reaction

320183
stoichiometry: 1.0
species: 378155
type: SpeciesReference

378557
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Xylulose
type: Species

378203
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Methylglyoxal
type: Species

381114
units: 304591
value: 0.0
type: LocalParameter

310925
stoichiometry: 7.92
species: 378083
type: SpeciesReference

383066
units: 304591
value: 0.0
type: LocalParameter

381451
units: 304591
value: 0.0
type: LocalParameter

320304
stoichiometry: 1.0
species: 378212
type: SpeciesReference

312340
stoichiometry: 1.0
species: 378230
type: SpeciesReference

382034
units: 304591
value: 0.0
type: LocalParameter

380374
units: 304591
value: 0.0
type: LocalParameter

380948
units: 304591
value: 1000.0
type: LocalParameter

380521
units: 304591
value: 0.0
type: LocalParameter

382584
units: 304591
value: 1000.0
type: LocalParameter

382238
units: 304591
value: -1000.0
type: LocalParameter

378335
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Phenylalanine
type: Species

382035
units: 304591
value: -1000.0
type: LocalParameter

317285
stoichiometry: 1.0
species: 377694
type: SpeciesReference

378972
kinetic law: 312595
type: Reaction
product: 312570
reactant: 312545
reactant: 312533
notes: GENE_ASSOCIATION: (51181.1) SUBSYSTEM: Pentose and Glucuronate Interconversions
reactant: 312558
name: xylulosereductase
fast: false
reversible: true
product: 312583

378281
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Superoxide anion
type: Species

315620
stoichiometry: 1.0
species: 377969
type: SpeciesReference

378176
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Lysine
type: Species

379107
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 315390
reactant: 315340
reversible: true
name: D-Serine/Glutaminereversibleexchange
product: 315377
fast: false
product: 315365
reactant: 315353

383067
units: 304591
value: -1000.0
type: LocalParameter

382188
units: 304591
value: 0.0
type: LocalParameter

312570
stoichiometry: 1.0
species: 378227
type: SpeciesReference

380375
units: 304591
value: 0.0
type: LocalParameter

382237
units: 304591
value: 0.0
type: LocalParameter

379431
kinetic law: 321427
product: 321415
reactant: 321402
notes: GENE_ASSOCIATION: (2944.1) or (2944.2) SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: true
name: 13-cis-retinoicacidisomerase
type: Reaction

379197
type: Reaction
reactant: 317068
reversible: true
product: 317092
reactant: 317080
name: bicarbonatetransport(Na/HCO31:2cotransport)
kinetic law: 317117
product: 317104
notes: GENE_ASSOCIATION: (8671.1) SUBSYSTEM: Transport, Extracellular
fast: false

382189
units: 304591
value: -1000.0
type: LocalParameter

309018
stoichiometry: 1.0
species: 378077
type: SpeciesReference

315038
stoichiometry: 1.0
species: 377817
type: SpeciesReference

305401
stoichiometry: 1.0
species: 378551
type: SpeciesReference

382820
units: 304591
value: 0.0
type: LocalParameter

319520
stoichiometry: 1.0
species: 378557
type: SpeciesReference

383068
units: 304591
value: 13.5135135135135
type: LocalParameter

306216
stoichiometry: 1.0
species: 377694
type: SpeciesReference

318554
stoichiometry: 1.0
species: 377781
type: SpeciesReference

381084
units: 304591
value: 0.0
type: LocalParameter

322865
stoichiometry: 1.0
species: 378338
type: SpeciesReference

314629
stoichiometry: 1.0
species: 377595
type: SpeciesReference

382037
units: 304591
value: 1000.0
type: LocalParameter

378200
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Methylglyoxal
type: Species

304699
stoichiometry: 1.0
species: 377933
type: SpeciesReference

379434
kinetic law: 321475
product: 321463
reactant: 321451
reactant: 321439
notes: GENE_ASSOCIATION: SUBSYSTEM: Vitamin A Metabolism
fast: false
reversible: false
name: 13-cis-4-oxo-retinoicacidformation(oxidation)
type: Reaction

318156
stoichiometry: 1.0
species: 378209
type: SpeciesReference

324827
stoichiometry: 1.0
species: 377850
type: SpeciesReference

320232
stoichiometry: 1.0
species: 378212
type: SpeciesReference

383069
units: 304591
value: 0.0
type: LocalParameter

381454
units: 304591
value: 0.0
type: LocalParameter

320510
stoichiometry: 1.0
species: 377911
type: SpeciesReference

309645
stoichiometry: 2.0
species: 378074
type: SpeciesReference

380087
units: 304591
value: 0.0
type: LocalParameter

380881
units: 304591
value: 0.0
type: LocalParameter

381085
units: 304591
value: 0.0
type: LocalParameter

306639
stoichiometry: 1.0
species: 378359
type: SpeciesReference

323958
stoichiometry: 1.0
species: 378020
type: SpeciesReference

321329
stoichiometry: 1.0
species: 378293
type: SpeciesReference

311712
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381118
units: 304591
value: 1000.0
type: LocalParameter

378179
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: monoacylglycerol 2 (homo sapiens)
type: Species

382586
units: 304591
value: 0.0
type: LocalParameter

378975
reactant: 312607
product: 312643
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
product: 312655
product: 312631
kinetic law: 312667
reactant: 312619
name: xylitoldehydrogenase(D-xyulose-forming)
reversible: true
fast: false

382822
units: 304591
value: 1000.0
type: LocalParameter

378284
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Superoxide anion
type: Species

379104
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
product: 315304
kinetic law: 315328
name: D-Serine/Glycinereversibleexchange
reversible: true
reactant: 315292
fast: false
product: 315316
reactant: 315280

378762
reversible: true
product: 308161
product: 308185
kinetic law: 308197
fast: false
type: Reaction
name: glycinehydroxymethyltransferase,reversible
reactant: 308149
product: 308173
reactant: 308137
notes: GENE_ASSOCIATION: (6470.1) or (6470.2) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism

381568
units: 304591
value: 1000.0
type: LocalParameter

379653
kinetic law: 324839
reactant: 324827
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382245
units: 304591
value: -1000.0
type: LocalParameter

382824
units: 304591
value: 0.0
type: LocalParameter

379548
kinetic law: 323308
product: 323296
reactant: 323284
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
type: Reaction

383279
units: 304591
value: -1000.0
type: LocalParameter

380738
units: 304591
value: 1000.0
type: LocalParameter

380524
units: 304591
value: 0.0
type: LocalParameter

311784
stoichiometry: 1.0
species: 378236
type: SpeciesReference

380451
units: 304591
value: 0.0
type: LocalParameter

313622
stoichiometry: 1.0
species: 378314
type: SpeciesReference

382361
units: 304591
value: 0.0
type: LocalParameter

379907
units: 304591
value: 0.0
type: LocalParameter

380190
units: 304591
value: 0.0
type: LocalParameter

378978
kinetic law: 312740
product: 312716
notes: GENE_ASSOCIATION: SUBSYSTEM: Pentose and Glucuronate Interconversions
fast: false
reactant: 312679
reactant: 312692
reversible: true
reactant: 312704
type: Reaction
name: gulonatedehydrogenase,endoplasmicreticulum
product: 312728

312195
stoichiometry: 1.0
species: 377951
type: SpeciesReference

383063
units: 304591
value: 0.0
type: LocalParameter

381674
units: 304591
value: 1000.0
type: LocalParameter

379440
kinetic law: 321547
product: 321535
reactant: 321523
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: 13-cis-retinoicacidtransport,nuclear
type: Reaction

316525
stoichiometry: 1.0
species: 378158
type: SpeciesReference

377939
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: GDP
type: Species

382577
units: 304591
value: 1000.0
type: LocalParameter

378741
kinetic law: 307824
product: 307812
reactant: 307800
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: coenzymeAtransport,nuclear
type: Reaction

380381
units: 304591
value: 0.0
type: LocalParameter

307666
stoichiometry: 1.0
species: 378215
type: SpeciesReference

326539
stoichiometry: 1.0
species: 377655
type: SpeciesReference

310272
stoichiometry: 1.0
species: 377589
type: SpeciesReference

322925
stoichiometry: 1.0
species: 378077
type: SpeciesReference

309332
stoichiometry: 1.0
species: 377787
type: SpeciesReference

380525
units: 304591
value: -1000.0
type: LocalParameter

313573
stoichiometry: 1.0
species: 378194
type: SpeciesReference

383130
units: 304591
value: 0.0
type: LocalParameter

383062
units: 304591
value: 0.0
type: LocalParameter

378062
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: H2O
type: Species

382826
units: 304591
value: 0.0
type: LocalParameter

316417
stoichiometry: 1.0
species: 377685
type: SpeciesReference

380384
units: 304591
value: 0.0
type: LocalParameter

382247
units: 304591
value: 1000.0
type: LocalParameter

382363
units: 304591
value: 0.0
type: LocalParameter

381081
units: 304591
value: 0.0
type: LocalParameter

383276
units: 304591
value: 13.5135135135135
type: LocalParameter

380385
units: 304591
value: -1000.0
type: LocalParameter

313465
stoichiometry: 1.0
species: 378299
type: SpeciesReference

380300
units: 304591
value: 1000.0
type: LocalParameter

383065
units: 304591
value: 0.0
type: LocalParameter

381676
units: 304591
value: 0.0
type: LocalParameter

379113
reactant: 315475
name: L-alanine/glutaminereversibleexchange
fast: false
reactant: 315463
type: Reaction
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 315511
reversible: true
product: 315499
product: 315487

378765
product: 308245
type: Reaction
notes: GENE_ASSOCIATION: (7001.3) or (5052.3) or (2876.2) or (5052.2) or (2876.1) or (5052.1) or (7001.1) or (2879.1) or (7001.2) SUBSYSTEM: Glutathione Metabolism
reversible: true
name: glutathioneperidoxase
reactant: 308209
product: 308233
kinetic law: 308257
reactant: 308221
fast: false

379867
kinetic law: 326575
reactant: 326563
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: 4-Aminobutanoateexchange
type: Reaction

305620
stoichiometry: 1.0
species: 377652
type: SpeciesReference

379194
reactant: 317008
type: Reaction
fast: false
name: bicarbonatetransport(Cl-/HCO3-exchange)
notes: GENE_ASSOCIATION: (6521.1) SUBSYSTEM: Transport, Extracellular
reactant: 317020
product: 317044
reversible: true
product: 317032
kinetic law: 317056

383278
units: 304591
value: 0.0
type: LocalParameter

379656
kinetic law: 324863
reactant: 324851
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382579
units: 304591
value: 0.0
type: LocalParameter

307932
stoichiometry: 1.0
species: 378077
type: SpeciesReference

380301
units: 304591
value: 0.0
type: LocalParameter

382364
units: 304591
value: 0.0
type: LocalParameter

380598
units: 304591
value: 1000.0
type: LocalParameter

380454
units: 304591
value: 0.0
type: LocalParameter

383277
units: 304591
value: 0.0
type: LocalParameter

307860
stoichiometry: 1.0
species: 378077
type: SpeciesReference

383064
units: 304591
value: 13.5135135135135
type: LocalParameter

323752
stoichiometry: 1.0
species: 378530
type: SpeciesReference

324152
stoichiometry: 1.0
species: 378380
type: SpeciesReference

381461
units: 304591
value: 0.0
type: LocalParameter

378744
name: ribosetransportinviaprotonsymporter
type: Reaction
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
reversible: false
fast: false
reactant: 307836
product: 307860
product: 307872
kinetic law: 307884
reactant: 307848

382366
units: 304591
value: 1000.0
type: LocalParameter

321402
stoichiometry: 1.0
species: 378428
type: SpeciesReference

377936
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glycolaldehyde
type: Species

379110
name: L-alanine/glycinereversibleexchange
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
product: 315427
reversible: true
fast: false
product: 315439
type: Reaction
reactant: 315402
reactant: 315415
kinetic law: 315451

377823
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: CO2
type: Species

321257
stoichiometry: 1.0
species: 378113
type: SpeciesReference

317879
stoichiometry: 1.0
species: 378095
type: SpeciesReference

380100
units: 304591
value: 0.0
type: LocalParameter

315487
stoichiometry: 1.0
species: 377724
type: SpeciesReference

383133
units: 304591
value: 0.0
type: LocalParameter

380528
units: 304591
value: 1000.0
type: LocalParameter

309769
stoichiometry: 1.0
species: 377939
type: SpeciesReference

380194
units: 304591
value: 1000.0
type: LocalParameter

318762
stoichiometry: 1.0
species: 377814
type: SpeciesReference

383274
units: 304591
value: 0.0
type: LocalParameter

382240
units: 304591
value: 1000.0
type: LocalParameter

308631
stoichiometry: 1.0
species: 378407
type: SpeciesReference

380591
units: 304591
value: 0.0
type: LocalParameter

315415
stoichiometry: 1.0
species: 377993
type: SpeciesReference

382827
units: 304591
value: 0.0
type: LocalParameter

380101
units: 304591
value: 0.0
type: LocalParameter

383135
units: 304591
value: -1000.0
type: LocalParameter

379650
kinetic law: 324815
reactant: 324803
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

378828
product: 309356
notes: GENE_ASSOCIATION: (5151.4) or (5151.5) or (5151.3) or (5151.1) or (5151.2) SUBSYSTEM: Nucleotides
product: 309368
reactant: 309332
name: 3',5'-cyclic-nucleotidephosphodiesterase
fast: false
type: Reaction
kinetic law: 309380
reactant: 309344
reversible: false

310707
stoichiometry: 1.0
species: 378413
type: SpeciesReference

383134
units: 304591
value: 0.0
type: LocalParameter

378768
kinetic law: 308293
product: 308281
reactant: 308269
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Mitochondrial
fast: false
reversible: true
name: L-prolinetransport,mitochondrial
type: Reaction

383275
units: 304591
value: -1000.0
type: LocalParameter

322383
stoichiometry: 1.0
species: 377685
type: SpeciesReference

380888
units: 304591
value: 1000.0
type: LocalParameter

313356
stoichiometry: 1.0
species: 378062
type: SpeciesReference

379864
kinetic law: 326551
reactant: 326539
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Acetateexchange
type: Reaction

382368
units: 304591
value: 0.0
type: LocalParameter

304603
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

325913
stoichiometry: 1.0
species: 378176
type: SpeciesReference

383061
units: 304591
value: 0.0
type: LocalParameter

383131
units: 304591
value: -1000.0
type: LocalParameter

308497
stoichiometry: 1.0
species: 378056
type: SpeciesReference

383272
units: 304591
value: 13.5135135135135
type: LocalParameter

380304
units: 304591
value: 0.0
type: LocalParameter

382242
units: 304591
value: 0.0
type: LocalParameter

380595
units: 304591
value: -1000.0
type: LocalParameter

381760
units: 304591
value: 0.0
type: LocalParameter

382182
units: 304591
value: -1000.0
type: LocalParameter

381121
units: 304591
value: 0.0
type: LocalParameter

309980
stoichiometry: 1.0
species: 378215
type: SpeciesReference

379191
fast: false
reversible: true
type: Reaction
product: 316984
kinetic law: 316996
product: 316972
name: D-glucosetransportinviaprotonsymport
notes: GENE_ASSOCIATION: (6524.1) SUBSYSTEM: Transport, Extracellular
reactant: 316948
reactant: 316960

377820
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: CO2
type: Species

319869
stoichiometry: 1.0
species: 378338
type: SpeciesReference

377933
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glyceraldehyde 3-phosphate
type: Species

318518
stoichiometry: 1.0
species: 378509
type: SpeciesReference

382829
units: 304591
value: 1000.0
type: LocalParameter

382244
units: 304591
value: 0.0
type: LocalParameter

378341
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Phosphate
type: Species

378065
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: H2O
type: Species

381672
units: 304591
value: 0.0
type: LocalParameter

381839
units: 304591
value: -1000.0
type: LocalParameter

381671
units: 304591
value: 0.0
type: LocalParameter

312885
stoichiometry: 1.0
species: 377874
type: SpeciesReference

325744
stoichiometry: 1.0
species: 378014
type: SpeciesReference

383132
units: 304591
value: 13.5135135135135
type: LocalParameter

380191
units: 304591
value: -1000.0
type: LocalParameter

380305
units: 304591
value: -1000.0
type: LocalParameter

380594
units: 304591
value: 0.0
type: LocalParameter

383273
units: 304591
value: 0.0
type: LocalParameter

305109
stoichiometry: 1.0
species: 377769
type: SpeciesReference

383060
units: 304591
value: 13.5135135135135
type: LocalParameter

382181
units: 304591
value: 0.0
type: LocalParameter

381762
units: 304591
value: 0.0
type: LocalParameter

378407
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Pyruvate
type: Species

308970
stoichiometry: 1.0
species: 378077
type: SpeciesReference

307727
stoichiometry: 1.0
species: 377987
type: SpeciesReference

325261
stoichiometry: 1.0
species: 378572
type: SpeciesReference

324370
stoichiometry: 1.0
species: 378530
type: SpeciesReference

381838
units: 304591
value: 0.0
type: LocalParameter

381988
units: 304591
value: 1000.0
type: LocalParameter

309878
stoichiometry: 1.0
species: 378029
type: SpeciesReference

311420
stoichiometry: 1.0
species: 378083
type: SpeciesReference

378825
kinetic law: 309320
product: 309307
product: 309295
reactant: 309283
notes: GENE_ASSOCIATION: (112.1) or (112.2) SUBSYSTEM: Nucleotides
fast: false
reversible: false
name: adenylatecyclase
type: Reaction

380104
units: 304591
value: 1000.0
type: LocalParameter

321764
stoichiometry: 1.0
species: 378227
type: SpeciesReference

383138
units: 304591
value: 0.0
type: LocalParameter

382719
units: 304591
value: 0.0
type: LocalParameter

382689
units: 304591
value: 1000.0
type: LocalParameter

378068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: H2O
type: Species

382475
units: 304591
value: 0.0
type: LocalParameter

377930
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Fumarate
type: Species

381763
units: 304591
value: -1000.0
type: LocalParameter

307245
stoichiometry: 1.0
species: 377817
type: SpeciesReference

313247
stoichiometry: 1.0
species: 377856
type: SpeciesReference

308521
stoichiometry: 1.0
species: 377826
type: SpeciesReference

322492
stoichiometry: 1.0
species: 378308
type: SpeciesReference

380731
units: 304591
value: 0.0
type: LocalParameter

325164
stoichiometry: 1.0
species: 377811
type: SpeciesReference

310816
stoichiometry: 1.0
species: 378065
type: SpeciesReference

380197
units: 304591
value: 0.0
type: LocalParameter

325407
stoichiometry: 1.0
species: 378524
type: SpeciesReference

383139
units: 304591
value: -1000.0
type: LocalParameter

379861
kinetic law: 326527
reactant: 326515
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Alanineexchange
type: Reaction

382476
units: 304591
value: 0.0
type: LocalParameter

377826
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Coenzyme A
type: Species

326805
stoichiometry: 1.0
species: 378062
type: SpeciesReference

381008
units: 304591
value: 1000.0
type: LocalParameter

318036
stoichiometry: 1.0
species: 378263
type: SpeciesReference

326757
stoichiometry: 1.0
species: 378080
type: SpeciesReference

317393
stoichiometry: 1.0
species: 378209
type: SpeciesReference

324755
stoichiometry: 1.0
species: 377993
type: SpeciesReference

321027
stoichiometry: 1.0
species: 378218
type: SpeciesReference

381561
units: 304591
value: 0.0
type: LocalParameter

381836
units: 304591
value: 0.0
type: LocalParameter

383136
units: 304591
value: 13.5135135135135
type: LocalParameter

319400
stoichiometry: 1.0
species: 377948
type: SpeciesReference

378404
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Pyruvate
type: Species

310405
stoichiometry: 1.0
species: 377715
type: SpeciesReference

379542
kinetic law: 323195
product: 323182
reactant: 323169
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sphingosine-1-phosphatetransport
type: Reaction

378497
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 5,6,7,8-Tetrahydrofolate
type: Species

381765
units: 304591
value: 1000.0
type: LocalParameter

381231
units: 304591
value: 0.0
type: LocalParameter

312002
stoichiometry: 1.0
species: 378236
type: SpeciesReference

383137
units: 304591
value: 0.0
type: LocalParameter

382930
units: 304591
value: 0.0
type: LocalParameter

382609
units: 304591
value: 0.0
type: LocalParameter

319978
stoichiometry: 1.0
species: 378368
type: SpeciesReference

379089
reactant: 314954
notes: GENE_ASSOCIATION: (54407.1) SUBSYSTEM: Transport, Extracellular
reversible: false
fast: false
reactant: 314942
kinetic law: 314990
product: 314966
type: Reaction
product: 314978
name: L-histidinetransportinviasodiumsymport

382478
units: 304591
value: 1000.0
type: LocalParameter

380107
units: 304591
value: 0.0
type: LocalParameter

312679
stoichiometry: 1.0
species: 377963
type: SpeciesReference

381834
units: 304591
value: 1000.0
type: LocalParameter

315837
stoichiometry: 1.0
species: 377996
type: SpeciesReference

312086
stoichiometry: 1.0
species: 377904
type: SpeciesReference

308305
stoichiometry: 1.0
species: 377978
type: SpeciesReference

307510
stoichiometry: 1.0
species: 377978
type: SpeciesReference

313513
stoichiometry: 1.0
species: 377990
type: SpeciesReference

380455
units: 304591
value: -1000.0
type: LocalParameter

307377
stoichiometry: 1.0
species: 378212
type: SpeciesReference

310695
stoichiometry: 2.0
species: 378083
type: SpeciesReference

380734
units: 304591
value: 0.0
type: LocalParameter

305952
stoichiometry: 1.0
species: 378290
type: SpeciesReference

382715
units: 304591
value: 0.0
type: LocalParameter

379713
kinetic law: 325323
reactant: 325311
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 4-oxo-retonoicaciddemand
type: Reaction

378491
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Succinate
type: Species

381564
units: 304591
value: 0.0
type: LocalParameter

309440
stoichiometry: 1.0
species: 378461
type: SpeciesReference

321836
stoichiometry: 2.0
species: 378275
type: SpeciesReference

377658
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Acetate
type: Species

323058
stoichiometry: 1.0
species: 377895
type: SpeciesReference

379659
kinetic law: 324887
reactant: 324875
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

379904
units: 304591
value: 1000.0
type: LocalParameter

380735
units: 304591
value: 0.0
type: LocalParameter

382471
units: 304591
value: 1000.0
type: LocalParameter

381767
units: 304591
value: 0.0
type: LocalParameter

381004
units: 304591
value: 0.0
type: LocalParameter

379545
fast: false
reactant: 323234
product: 323260
notes: GENE_ASSOCIATION: (8574.1) SUBSYSTEM: Pyruvate Metabolism
product: 323247
reversible: false
name: Propane-1,2-diol:NAD+1-oxidoreductase
reactant: 323221
kinetic law: 323272
reactant: 323208
type: Reaction

382686
units: 304591
value: 0.0
type: LocalParameter

378401
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Pyridoxal
type: Species

382714
units: 304591
value: 0.0
type: LocalParameter

316791
stoichiometry: 1.0
species: 378176
type: SpeciesReference

381565
units: 304591
value: 0.0
type: LocalParameter

379224
reactant: 317636
notes: GENE_ASSOCIATION: (9058.1) SUBSYSTEM: Transport, Extracellular
reversible: true
type: Reaction
kinetic law: 317673
product: 317649
reactant: 317624
name: succinatetransportviasodiumsymport
product: 317661
fast: false

382607
units: 304591
value: 0.0
type: LocalParameter

381678
units: 304591
value: 0.0
type: LocalParameter

381351
units: 304591
value: 0.0
type: LocalParameter

381832
units: 304591
value: 0.0
type: LocalParameter

379901
units: 304591
value: -1000.0
type: LocalParameter

379900
kinetic law: 326841
reactant: 326829
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: D-Glucoseexchange
type: Reaction

379332
kinetic law: 319616
product: 319604
product: 319592
reactant: 319580
notes: GENE_ASSOCIATION: (226.2) or (229.1) or (226.3) or (226.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
fast: false
reversible: true
name: D-Fructose1-phosphateD-glyceraldehyde-3-phosphate-lyase
type: Reaction

381005
units: 304591
value: 0.0
type: LocalParameter

382687
units: 304591
value: -1000.0
type: LocalParameter

382717
units: 304591
value: 1000.0
type: LocalParameter

306084
stoichiometry: 1.0
species: 378077
type: SpeciesReference

377829
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Coenzyme A
type: Species

319388
stoichiometry: 1.0
species: 377945
type: SpeciesReference

379221
kinetic law: 317612
reversible: true
type: Reaction
notes: GENE_ASSOCIATION: (9058.1) SUBSYSTEM: Transport, Extracellular
reactant: 317563
reactant: 317575
fast: false
product: 317599
name: citratetransportviasodiumsymport
product: 317587

381679
units: 304591
value: 0.0
type: LocalParameter

378822
name: Glycolatedehydrogenase(NADP)
product: 309259
reactant: 309235
fast: false
reversible: false
type: Reaction
reactant: 309223
notes: GENE_ASSOCIATION: (9380.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
reactant: 309210
product: 309247
kinetic law: 309271

323861
stoichiometry: 1.0
species: 377784
type: SpeciesReference

381769
units: 304591
value: 0.0
type: LocalParameter

306783
stoichiometry: 1.0
species: 378182
type: SpeciesReference

319170
stoichiometry: 1.0
species: 377649
type: SpeciesReference

380458
units: 304591
value: 1000.0
type: LocalParameter

381831
units: 304591
value: 0.0
type: LocalParameter

382473
units: 304591
value: 0.0
type: LocalParameter

308413
stoichiometry: 1.0
species: 378065
type: SpeciesReference

323169
stoichiometry: 1.0
species: 378479
type: SpeciesReference

379710
kinetic law: 325298
reactant: 325286
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
type: Reaction

378494
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Succinyl-CoA
type: Species

382605
units: 304591
value: 1000.0
type: LocalParameter

321196
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380090
units: 304591
value: 0.0
type: LocalParameter

312280
stoichiometry: 1.0
species: 378362
type: SpeciesReference

378627
kinetic law: 305656
product: 305620
name: aldehydedehydrogenase(acetaldehyde,NAD)
notes: GENE_ASSOCIATION: (224.1) or (216.1) or (223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
reversible: false
product: 305644
product: 305632
reactant: 305583
reactant: 305596
fast: false
type: Reaction
reactant: 305608

380801
units: 304591
value: 0.0
type: LocalParameter

377607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2-Deoxy-D-ribose 5-phosphate
type: Species

380765
units: 304591
value: -1000.0
type: LocalParameter

382780
units: 304591
value: 1000.0
type: LocalParameter

381916
units: 304591
value: -1000.0
type: LocalParameter

381999
units: 304591
value: 0.0
type: LocalParameter

377712
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2-Oxoglutarate
type: Species

382995
units: 304591
value: 0.0
type: LocalParameter

305547
stoichiometry: 1.0
species: 378218
type: SpeciesReference

382922
units: 304591
value: 0.0
type: LocalParameter

379392
kinetic law: 320667
reversible: false
product: 320643
name: lipase
type: Reaction
reactant: 320619
fast: false
product: 320655
product: 320631
notes: GENE_ASSOCIATION: (4023.1) SUBSYSTEM: Triacylglycerol Synthesis
reactant: 320607

382633
units: 304591
value: 1000.0
type: LocalParameter

379317
fast: false
name: superoxidedismutase,peroxisome
reactant: 319206
product: 319230
reversible: false
type: Reaction
product: 319242
reactant: 319218
notes: GENE_ASSOCIATION: (6647.1) SUBSYSTEM: ROS Detoxification
kinetic law: 319255

319025
stoichiometry: 1.0
species: 377963
type: SpeciesReference

381044
units: 304591
value: 0.0
type: LocalParameter

382065
units: 304591
value: 1000.0
type: LocalParameter

380764
units: 304591
value: 0.0
type: LocalParameter

318953
stoichiometry: 1.0
species: 378245
type: SpeciesReference

318627
stoichiometry: 1.0
species: 378143
type: SpeciesReference

306530
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380091
units: 304591
value: 0.0
type: LocalParameter

377688
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Adenine
type: Species

317417
stoichiometry: 1.0
species: 378206
type: SpeciesReference

382994
units: 304591
value: 0.0
type: LocalParameter

382850
units: 304591
value: 13.5135135135135
type: LocalParameter

377793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Choline
type: Species

323728
stoichiometry: 1.0
species: 378512
type: SpeciesReference

380001
units: 304591
value: 0.0
type: LocalParameter

382923
units: 304591
value: 13.5135135135135
type: LocalParameter

378678
kinetic law: 306687
product: 306675
reactant: 306663
notes: GENE_ASSOCIATION: (50.1) SUBSYSTEM: Citric Acid Cycle
fast: false
reversible: true
name: Aconitatehydratase
type: Reaction

381045
units: 304591
value: 0.0
type: LocalParameter

381058
units: 304591
value: 1000.0
type: LocalParameter

381997
units: 304591
value: 0.0
type: LocalParameter

381054
units: 304591
value: 0.0
type: LocalParameter

382062
units: 304591
value: 0.0
type: LocalParameter

380428
units: 304591
value: 1000.0
type: LocalParameter

381918
units: 304591
value: 1000.0
type: LocalParameter

381311
units: 304591
value: 0.0
type: LocalParameter

380000
units: 304591
value: 0.0
type: LocalParameter

377685
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Acetylcholine
type: Species

382920
units: 304591
value: 0.0
type: LocalParameter

382993
units: 304591
value: 0.0
type: LocalParameter

377790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Carnosine
type: Species

314263
stoichiometry: 1.0
species: 378338
type: SpeciesReference

378566
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
type: Species

382635
units: 304591
value: 0.0
type: LocalParameter

378452
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Serine
type: Species

381258
units: 304591
value: 1000.0
type: LocalParameter

310465
stoichiometry: 1.0
species: 378494
type: SpeciesReference

378218
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide - reduced
type: Species

381055
units: 304591
value: 0.0
type: LocalParameter

382063
units: 304591
value: -1000.0
type: LocalParameter

380988
units: 304591
value: 0.0
type: LocalParameter

382991
units: 304591
value: 0.0
type: LocalParameter

312401
stoichiometry: 1.0
species: 378038
type: SpeciesReference

308149
stoichiometry: 1.0
species: 378497
type: SpeciesReference

323656
stoichiometry: 1.0
species: 378338
type: SpeciesReference

382209
units: 304591
value: 0.0
type: LocalParameter

382992
units: 304591
value: 13.5135135135135
type: LocalParameter

313029
stoichiometry: 1.0
species: 378074
type: SpeciesReference

304867
stoichiometry: 1.0
species: 377700
type: SpeciesReference

379314
kinetic law: 319194
product: 319182
reactant: 319170
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: true
name: Rgrouptopalmitateconversion
type: Reaction

305474
stoichiometry: 1.0
species: 377817
type: SpeciesReference

307329
stoichiometry: 1.0
species: 377930
type: SpeciesReference

383189
units: 304591
value: 0.0
type: LocalParameter

380761
units: 304591
value: 0.0
type: LocalParameter

319580
stoichiometry: 1.0
species: 378548
type: SpeciesReference

382990
units: 304591
value: 0.0
type: LocalParameter

380094
units: 304591
value: 1000.0
type: LocalParameter

306759
stoichiometry: 1.0
species: 378494
type: SpeciesReference

380644
units: 304591
value: 0.0
type: LocalParameter

318699
stoichiometry: 1.0
species: 377814
type: SpeciesReference

381995
units: 304591
value: 1000.0
type: LocalParameter

380805
units: 304591
value: -1000.0
type: LocalParameter

314954
stoichiometry: 1.0
species: 378209
type: SpeciesReference

308898
stoichiometry: 1.0
species: 377700
type: SpeciesReference

326298
stoichiometry: 1.0
species: 378149
type: SpeciesReference

382926
units: 304591
value: 0.0
type: LocalParameter

382069
units: 304591
value: 0.0
type: LocalParameter

321680
stoichiometry: 1.0
species: 378218
type: SpeciesReference

378458
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Serine
type: Species

319640
stoichiometry: 1.0
species: 378086
type: SpeciesReference

382700
units: 304591
value: 0.0
type: LocalParameter

378560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Xylulose
type: Species

319700
stoichiometry: 1.0
species: 378233
type: SpeciesReference

320111
stoichiometry: 1.0
species: 377565
type: SpeciesReference

382637
units: 304591
value: 0.0
type: LocalParameter

320631
stoichiometry: 1.0
species: 377646
type: SpeciesReference

309524
stoichiometry: 1.0
species: 377904
type: SpeciesReference

317068
stoichiometry: 2.0
species: 378095
type: SpeciesReference

381913
units: 304591
value: 0.0
type: LocalParameter

379728
kinetic law: 325443
reactant: 325431
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Retinoateexchange
type: Reaction

311832
stoichiometry: 1.0
species: 377972
type: SpeciesReference

319929
stoichiometry: 1.0
species: 378074
type: SpeciesReference

382927
units: 304591
value: 13.5135135135135
type: LocalParameter

380157
units: 304591
value: 0.0
type: LocalParameter

379035
fast: false
kinetic law: 313935
reversible: false
product: 313911
type: Reaction
reactant: 313887
product: 313923
reactant: 313875
notes: GENE_ASSOCIATION: (5297.1) SUBSYSTEM: Inositol Phosphate Metabolism
name: phosphatidylinositol-5-phosphate4-kinase
product: 313899

382701
units: 304591
value: -1000.0
type: LocalParameter

306855
stoichiometry: 1.0
species: 377930
type: SpeciesReference

382638
units: 304591
value: -1000.0
type: LocalParameter

313380
stoichiometry: 1.0
species: 378341
type: SpeciesReference

322286
stoichiometry: 1.0
species: 378422
type: SpeciesReference

311045
stoichiometry: 1.0
species: 378071
type: SpeciesReference

380985
units: 304591
value: -1000.0
type: LocalParameter

321945
stoichiometry: 1.0
species: 378521
type: SpeciesReference

320449
stoichiometry: 1.0
species: 377640
type: SpeciesReference

383187
units: 304591
value: -1000.0
type: LocalParameter

308787
stoichiometry: 1.0
species: 378059
type: SpeciesReference

381993
units: 304591
value: -1000.0
type: LocalParameter

316043
stoichiometry: 1.0
species: 378077
type: SpeciesReference

379311
kinetic law: 319158
product: 319146
reactant: 319134
reactant: 319122
notes: GENE_ASSOCIATION: SUBSYSTEM: R Group Synthesis
fast: false
reversible: true
name: Rgroupcoenzymealigase
type: Reaction

377877
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyinosine
type: Species

316887
stoichiometry: 1.0
species: 378062
type: SpeciesReference

315158
stoichiometry: 1.0
species: 377993
type: SpeciesReference

382924
units: 304591
value: 0.0
type: LocalParameter

381048
units: 304591
value: 1000.0
type: LocalParameter

320002
stoichiometry: 1.0
species: 378077
type: SpeciesReference

315765
stoichiometry: 1.0
species: 377853
type: SpeciesReference

379038
notes: GENE_ASSOCIATION: (55586.1) SUBSYSTEM: Inositol Phosphate Metabolism
type: Reaction
reactant: 313947
product: 313995
name: inositoloxygenase
fast: false
product: 313983
reversible: false
kinetic law: 314007
product: 313971
reactant: 313959

380004
units: 304591
value: 1000.0
type: LocalParameter

310126
stoichiometry: 1.0
species: 377586
type: SpeciesReference

380984
units: 304591
value: 0.0
type: LocalParameter

380097
units: 304591
value: 0.0
type: LocalParameter

383188
units: 304591
value: 0.0
type: LocalParameter

308824
stoichiometry: 2.0
species: 378077
type: SpeciesReference

381915
units: 304591
value: 0.0
type: LocalParameter

382067
units: 304591
value: 0.0
type: LocalParameter

380641
units: 304591
value: 0.0
type: LocalParameter

381992
units: 304591
value: 0.0
type: LocalParameter

380804
units: 304591
value: 0.0
type: LocalParameter

378563
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
type: Species

307051
stoichiometry: 1.0
species: 377592
type: SpeciesReference

317141
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382925
units: 304591
value: 0.0
type: LocalParameter

378455
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Serine
type: Species

322721
stoichiometry: 1.0
species: 378473
type: SpeciesReference

309223
stoichiometry: 1.0
species: 378077
type: SpeciesReference

378161
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Leucine
type: Species

381108
units: 304591
value: 1000.0
type: LocalParameter

314521
stoichiometry: 1.0
species: 378272
type: SpeciesReference

318276
stoichiometry: 1.0
species: 378209
type: SpeciesReference

379395
kinetic law: 320703
product: 320691
reactant: 320679
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
type: Reaction

306904
stoichiometry: 1.0
species: 378017
type: SpeciesReference

318120
stoichiometry: 1.0
species: 378164
type: SpeciesReference

381611
units: 304591
value: 1000.0
type: LocalParameter

321571
stoichiometry: 1.0
species: 377571
type: SpeciesReference

320220
stoichiometry: 1.0
species: 377562
type: SpeciesReference

379692
kinetic law: 325152
reactant: 325140
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

381990
units: 304591
value: 0.0
type: LocalParameter

382575
units: 304591
value: 0.0
type: LocalParameter

379032
reversible: true
name: glutathioneperoxidase(e)
product: 313839
reactant: 313827
type: Reaction
product: 313851
kinetic law: 313863
reactant: 313815
fast: false
notes: GENE_ASSOCIATION: (2878.1) SUBSYSTEM: Glutathione Metabolism

317345
stoichiometry: 1.0
species: 378134
type: SpeciesReference

382857
units: 304591
value: 13.5135135135135
type: LocalParameter

320099
stoichiometry: 1.0
species: 378236
type: SpeciesReference

378212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide
type: Species

383223
units: 304591
value: -1000.0
type: LocalParameter

317624
stoichiometry: 2.0
species: 378209
type: SpeciesReference

382294
units: 304591
value: 0.0
type: LocalParameter

380535
units: 304591
value: -1000.0
type: LocalParameter

383222
units: 304591
value: 0.0
type: LocalParameter

379836
kinetic law: 326310
reactant: 326298
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Lactateexchange
type: Reaction

380914
units: 304591
value: 0.0
type: LocalParameter

382177
units: 304591
value: 1000.0
type: LocalParameter

307438
stoichiometry: 1.0
species: 377895
type: SpeciesReference

324659
stoichiometry: 1.0
species: 378173
type: SpeciesReference

381465
units: 304591
value: 0.0
type: LocalParameter

382203
units: 304591
value: 0.0
type: LocalParameter

317357
stoichiometry: 2.0
species: 378206
type: SpeciesReference

382179
units: 304591
value: 0.0
type: LocalParameter

311724
stoichiometry: 1.0
species: 378170
type: SpeciesReference

378167
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: lignoceric acid
type: Species

383224
units: 304591
value: 0.0
type: LocalParameter

382574
units: 304591
value: 0.0
type: LocalParameter

323234
stoichiometry: 1.0
species: 378218
type: SpeciesReference

380915
units: 304591
value: 0.0
type: LocalParameter

323247
stoichiometry: 1.0
species: 377562
type: SpeciesReference

380534
units: 304591
value: 0.0
type: LocalParameter

308077
stoichiometry: 1.0
species: 377736
type: SpeciesReference

323392
stoichiometry: 1.0
species: 378050
type: SpeciesReference

315656
stoichiometry: 1.0
species: 378503
type: SpeciesReference

381464
units: 304591
value: 0.0
type: LocalParameter

378164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: lignoceric acid
type: Species

382855
units: 304591
value: 0.0
type: LocalParameter

382928
units: 304591
value: 0.0
type: LocalParameter

379398
name: Aldosereductase
reactant: 320715
product: 320763
type: Reaction
fast: false
reactant: 320739
product: 320751
reversible: false
kinetic law: 320787
reactant: 320727
product: 320775
notes: GENE_ASSOCIATION: (231.1) SUBSYSTEM: Glycine, Serine, and Threonine Metabolism

378347
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Phosphate
type: Species

317297
stoichiometry: 2.0
species: 378206
type: SpeciesReference

382202
units: 304591
value: 0.0
type: LocalParameter

381105
units: 304591
value: 0.0
type: LocalParameter

382175
units: 304591
value: 0.0
type: LocalParameter

312352
stoichiometry: 1.0
species: 377715
type: SpeciesReference

383220
units: 304591
value: 0.0
type: LocalParameter

382572
units: 304591
value: 0.0
type: LocalParameter

310913
stoichiometry: 4.0
species: 377920
type: SpeciesReference

308934
stoichiometry: 1.0
species: 378212
type: SpeciesReference

383078
units: 304591
value: 0.0
type: LocalParameter

316393
stoichiometry: 1.0
species: 377676
type: SpeciesReference

315002
stoichiometry: 1.0
species: 377559
type: SpeciesReference

377799
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Choline
type: Species

378092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Bicarbonate
type: Species

380007
units: 304591
value: 0.0
type: LocalParameter

379467
kinetic law: 321994
product: 321982
reactant: 321969
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: false
name: urateexportfromcytosol
type: Reaction

382929
units: 304591
value: 0.0
type: LocalParameter

378672
product: 306566
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: (5168.1) SUBSYSTEM: NAD Metabolism
name: DeaminidoNADdiphosphatase
reactant: 306530
product: 306554
product: 306542
fast: false
reactant: 306517
kinetic law: 306578

321463
stoichiometry: 2.0
species: 377568
type: SpeciesReference

316248
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381318
units: 304591
value: 1000.0
type: LocalParameter

381104
units: 304591
value: 0.0
type: LocalParameter

309006
stoichiometry: 1.0
species: 377652
type: SpeciesReference

309114
stoichiometry: 1.0
species: 378275
type: SpeciesReference

379185
kinetic law: 316875
product: 316863
reactant: 316851
notes: GENE_ASSOCIATION: (6526.1) or (6523.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: sodiumtransport(uniport)
type: Reaction

309890
stoichiometry: 1.0
species: 378059
type: SpeciesReference

379839
kinetic law: 326334
reactant: 326322
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: K+exchange
type: Reaction

383221
units: 304591
value: 0.0
type: LocalParameter

382293
units: 304591
value: 0.0
type: LocalParameter

381911
units: 304591
value: 1000.0
type: LocalParameter

383079
units: 304591
value: -1000.0
type: LocalParameter

378002
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glyceraldehyde
type: Species

383227
units: 304591
value: -1000.0
type: LocalParameter

382349
units: 304591
value: 0.0
type: LocalParameter

314496
stoichiometry: 1.0
species: 378083
type: SpeciesReference

377796
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Choline
type: Species

382999
units: 304591
value: 0.0
type: LocalParameter

318494
stoichiometry: 1.0
species: 378515
type: SpeciesReference

306396
stoichiometry: 1.0
species: 378134
type: SpeciesReference

380874
units: 304591
value: 0.0
type: LocalParameter

306420
stoichiometry: 1.0
species: 378116
type: SpeciesReference

382570
units: 304591
value: 1000.0
type: LocalParameter

380531
units: 304591
value: 0.0
type: LocalParameter

382298
units: 304591
value: 0.0
type: LocalParameter

381041
units: 304591
value: 0.0
type: LocalParameter

383228
units: 304591
value: 0.0
type: LocalParameter

378569
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
type: Species

379695
kinetic law: 325176
reactant: 325164
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

320195
stoichiometry: 1.0
species: 378218
type: SpeciesReference

314375
stoichiometry: 1.0
species: 377700
type: SpeciesReference

378215
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide
type: Species

378344
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Phosphate
type: Species

382630
units: 304591
value: 0.0
type: LocalParameter

382207
units: 304591
value: 0.0
type: LocalParameter

379602
kinetic law: 324430
reactant: 324418
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

315983
stoichiometry: 1.0
species: 377981
type: SpeciesReference

377601
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 25-Hydroxyvitamin D3
type: Species

326106
stoichiometry: 1.0
species: 378539
type: SpeciesReference

382854
units: 304591
value: 0.0
type: LocalParameter

314302
stoichiometry: 1.0
species: 378308
type: SpeciesReference

326202
stoichiometry: 1.0
species: 378380
type: SpeciesReference

382998
units: 304591
value: 0.0
type: LocalParameter

321607
stoichiometry: 1.0
species: 378365
type: SpeciesReference

377715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: 2-Oxoglutarate
type: Species

318736
stoichiometry: 1.0
species: 378206
type: SpeciesReference

381690
units: 304591
value: 0.0
type: LocalParameter

306048
stoichiometry: 1.0
species: 377769
type: SpeciesReference

378735
kinetic law: 307751
product: 307739
reactant: 307727
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: glyoxylatetransport,peroxisomal
type: Reaction

380911
units: 304591
value: 0.0
type: LocalParameter

382174
units: 304591
value: 0.0
type: LocalParameter

383225
units: 304591
value: 0.0
type: LocalParameter

382631
units: 304591
value: -1000.0
type: LocalParameter

378675
product: 306639
fast: false
reactant: 306590
name: nicotinate-nucleotideadenylyltransferase
product: 306627
kinetic law: 306651
reversible: false
reactant: 306614
notes: GENE_ASSOCIATION: (5168.1) SUBSYSTEM: NAD Metabolism
reactant: 306602
type: Reaction

382347
units: 304591
value: 0.0
type: LocalParameter

381101
units: 304591
value: 0.0
type: LocalParameter

379188
kinetic law: 316936
product: 316924
product: 316911
reactant: 316899
reactant: 316887
fast: false
reversible: true
name: urea,watercotransport
type: Reaction

313718
stoichiometry: 1.0
species: 378077
type: SpeciesReference

382997
units: 304591
value: 0.0
type: LocalParameter

312969
stoichiometry: 1.0
species: 378236
type: SpeciesReference

381468
units: 304591
value: 1000.0
type: LocalParameter

381315
units: 304591
value: -1000.0
type: LocalParameter

322347
stoichiometry: 1.0
species: 378347
type: SpeciesReference

323500
stoichiometry: 1.0
species: 377583
type: SpeciesReference

377718
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Alanine
type: Species

310357
stoichiometry: 1.0
species: 377559
type: SpeciesReference

378738
kinetic law: 307787
product: 307775
reactant: 307763
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Nuclear
fast: false
reversible: true
name: acetyl-CoAtransport,nuclear
type: Reaction

320907
stoichiometry: 1.0
species: 378359
type: SpeciesReference

382296
units: 304591
value: 1000.0
type: LocalParameter

383226
units: 304591
value: 0.0
type: LocalParameter

382205
units: 304591
value: 1000.0
type: LocalParameter

304976
stoichiometry: 1.0
species: 377914
type: SpeciesReference

377682
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetylcholine
type: Species

382852
units: 304591
value: 0.0
type: LocalParameter

382996
units: 304591
value: 13.5135135135135
type: LocalParameter

381314
units: 304591
value: 0.0
type: LocalParameter

313138
stoichiometry: 1.0
species: 378077
type: SpeciesReference

377604
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: 2-Deoxy-D-ribose 1-phosphate
type: Species

380871
units: 304591
value: 0.0
type: LocalParameter

380318
units: 304591
value: 1000.0
type: LocalParameter

381051
units: 304591
value: 0.0
type: LocalParameter

379605
kinetic law: 324454
reactant: 324442
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382172
units: 304591
value: 0.0
type: LocalParameter

318840
stoichiometry: 1.0
species: 378248
type: SpeciesReference

313234
stoichiometry: 1.0
species: 377859
type: SpeciesReference

381885
units: 304591
value: 0.0
type: LocalParameter

381772
units: 304591
value: 1000.0
type: LocalParameter

382170
units: 304591
value: 1000.0
type: LocalParameter

311941
stoichiometry: 1.0
species: 377703
type: SpeciesReference

383073
units: 304591
value: 0.0
type: LocalParameter

326781
stoichiometry: 1.0
species: 378341
type: SpeciesReference

381804
units: 304591
value: 0.0
type: LocalParameter

378948
kinetic law: 312146
product: 312134
reactant: 312122
notes: GENE_ASSOCIATION: (5730.1) SUBSYSTEM: Eicosanoid Metabolism
fast: false
reversible: true
name: Prostaglandin-H2D-isomerase[Precursor]
type: Reaction

381683
units: 304591
value: 0.0
type: LocalParameter

379473
kinetic law: 322092
product: 322079
reactant: 322067
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: acetaldehydeperoxisomaldiffusion
type: Reaction

305837
stoichiometry: 1.0
species: 378419
type: SpeciesReference

382356
units: 304591
value: 0.0
type: LocalParameter

381538
units: 304591
value: 1000.0
type: LocalParameter

380878
units: 304591
value: 1000.0
type: LocalParameter

305037
stoichiometry: 1.0
species: 378338
type: SpeciesReference

383072
units: 304591
value: 13.5135135135135
type: LocalParameter

381803
units: 304591
value: 0.0
type: LocalParameter

314163
stoichiometry: 1.0
species: 378047
type: SpeciesReference

381111
units: 304591
value: 0.0
type: LocalParameter

319857
stoichiometry: 1.0
species: 378200
type: SpeciesReference

377945
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-glucurono-6,3-lactone
type: Species

378353
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Palmitoyl-CoA (n-C16:0CoA)
type: Species

382357
units: 304591
value: 0.0
type: LocalParameter

383219
units: 304591
value: -1000.0
type: LocalParameter

317563
stoichiometry: 1.0
species: 377805
type: SpeciesReference

381883
units: 304591
value: 1000.0
type: LocalParameter

383071
units: 304591
value: -1000.0
type: LocalParameter

324995
stoichiometry: 1.0
species: 377652
type: SpeciesReference

308643
stoichiometry: 1.0
species: 378077
type: SpeciesReference

307123
stoichiometry: 1.0
species: 378272
type: SpeciesReference

380314
units: 304591
value: 0.0
type: LocalParameter

380875
units: 304591
value: 0.0
type: LocalParameter

381806
units: 304591
value: 1000.0
type: LocalParameter

310018
stoichiometry: 1.0
species: 378221
type: SpeciesReference

378350
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Phosphate
type: Species

383218
units: 304591
value: 0.0
type: LocalParameter

382568
units: 304591
value: 0.0
type: LocalParameter

382410
units: 304591
value: 0.0
type: LocalParameter

377948
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: D-glucurono-6,3-lactone
type: Species

379251
kinetic law: 318096
product: 318084
reactant: 318072
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion
type: Reaction

379830
kinetic law: 326262
reactant: 326250
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Sodiumexchange
type: Reaction

378732
name: aldehydedehydrogenase(acetylaldehyde,NAD),mitochondrial
kinetic law: 307715
product: 307703
product: 307691
reactant: 307654
product: 307679
notes: GENE_ASSOCIATION: (217.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
reactant: 307666
fast: false
type: Reaction
reactant: 307642
reversible: false

382354
units: 304591
value: 0.0
type: LocalParameter

317843
stoichiometry: 1.0
species: 377778
type: SpeciesReference

381618
units: 304591
value: 1000.0
type: LocalParameter

322612
stoichiometry: 1.0
species: 378311
type: SpeciesReference

321245
stoichiometry: 1.0
species: 378110
type: SpeciesReference

383070
units: 304591
value: 0.0
type: LocalParameter

379608
kinetic law: 324478
reactant: 324466
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

380315
units: 304591
value: 0.0
type: LocalParameter

326635
stoichiometry: 1.0
species: 378269
type: SpeciesReference

381681
units: 304591
value: 1000.0
type: LocalParameter

378945
notes: GENE_ASSOCIATION: (3795.1) or (3795.2) SUBSYSTEM: Fructose and Mannose Metabolism
fast: false
reactant: 312062
reactant: 312050
product: 312098
product: 312086
name: ketohexokinase
product: 312074
type: Reaction
reversible: false
kinetic law: 312110

325528
stoichiometry: 1.0
species: 377637
type: SpeciesReference

316465
stoichiometry: 1.0
species: 378341
type: SpeciesReference

383217
units: 304591
value: 0.0
type: LocalParameter

315427
stoichiometry: 1.0
species: 377724
type: SpeciesReference

379686
kinetic law: 325103
reactant: 325091
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

381770
units: 304591
value: -1000.0
type: LocalParameter

380908
units: 304591
value: 1000.0
type: LocalParameter

380538
units: 304591
value: 1000.0
type: LocalParameter

381808
units: 304591
value: 0.0
type: LocalParameter

310779
stoichiometry: 4.0
species: 378077
type: SpeciesReference

313658
stoichiometry: 1.0
species: 378308
type: SpeciesReference

383077
units: 304591
value: 0.0
type: LocalParameter

382210
units: 304591
value: 0.0
type: LocalParameter

379539
kinetic law: 323156
product: 323144
reactant: 323131
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: sph1pintracellulartransport
type: Reaction

382291
units: 304591
value: 0.0
type: LocalParameter

313453
stoichiometry: 1.0
species: 378218
type: SpeciesReference

382412
units: 304591
value: 0.0
type: LocalParameter

381616
units: 304591
value: 0.0
type: LocalParameter

378098
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: trans-Hexadec-2-enoyl-CoA
type: Species

381534
units: 304591
value: 0.0
type: LocalParameter

324140
stoichiometry: 1.0
species: 378341
type: SpeciesReference

307896
stoichiometry: 1.0
species: 377655
type: SpeciesReference

383076
units: 304591
value: 0.0
type: LocalParameter

319291
stoichiometry: 2.0
species: 378143
type: SpeciesReference

307920
stoichiometry: 1.0
species: 377652
type: SpeciesReference

382352
units: 304591
value: 1000.0
type: LocalParameter

318337
stoichiometry: 1.0
species: 378209
type: SpeciesReference

319146
stoichiometry: 1.0
species: 377649
type: SpeciesReference

379182
product: 316815
kinetic law: 316839
reactant: 316791
notes: GENE_ASSOCIATION: (6584.1) SUBSYSTEM: Transport, Extracellular
reactant: 316803
name: L-lysinetransportinviasodiumsymport
fast: false
type: Reaction
reversible: false
product: 316827

381615
units: 304591
value: 0.0
type: LocalParameter

382567
units: 304591
value: 0.0
type: LocalParameter

382212
units: 304591
value: 1000.0
type: LocalParameter

381474
units: 304591
value: 0.0
type: LocalParameter

379101
reactant: 315219
fast: false
name: L-Serine/Glutaminereversibleexchange
notes: GENE_ASSOCIATION: (6520.1) SUBSYSTEM: Transport, Extracellular
reactant: 315231
type: Reaction
kinetic law: 315268
reversible: true
product: 315243
product: 315255

381688
units: 304591
value: 1000.0
type: LocalParameter

381535
units: 304591
value: 0.0
type: LocalParameter

311616
stoichiometry: 1.0
species: 378227
type: SpeciesReference

378942
product: 312026
reactant: 311989
reversible: false
kinetic law: 312038
reactant: 311977
product: 312014
reactant: 312002
name: Propane-1,2-diol:NADP+1-oxidoreductase
type: Reaction
notes: GENE_ASSOCIATION: (8574.1) or (231.1) or (10327.2) or (10327.1) SUBSYSTEM: Pyruvate Metabolism
fast: false

312558
stoichiometry: 1.0
species: 378560
type: SpeciesReference

309805
stoichiometry: 1.0
species: 377951
type: SpeciesReference

315292
stoichiometry: 1.0
species: 378452
type: SpeciesReference

383075
units: 304591
value: -1000.0
type: LocalParameter

380905
units: 304591
value: 0.0
type: LocalParameter

311481
stoichiometry: 1.0
species: 378227
type: SpeciesReference

308583
stoichiometry: 1.0
species: 378206
type: SpeciesReference

313634
stoichiometry: 1.0
species: 377700
type: SpeciesReference

381887
units: 304591
value: 0.0
type: LocalParameter

310574
stoichiometry: 1.0
species: 377715
type: SpeciesReference

379536
kinetic law: 323118
product: 323106
reactant: 323094
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: hdd2coaintracellulartransport
type: Reaction

379689
kinetic law: 325128
reactant: 325115
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

382778
units: 304591
value: -1000.0
type: LocalParameter

378798
name: Glycolaldehydedehydrogenase
fast: false
product: 308836
reversible: false
type: Reaction
notes: GENE_ASSOCIATION: (223.1) or (224.1) or (216.1) SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
kinetic law: 308849
product: 308824
reactant: 308775
product: 308812
reactant: 308787
reactant: 308800

381685
units: 304591
value: 0.0
type: LocalParameter

381471
units: 304591
value: 0.0
type: LocalParameter

383074
units: 304591
value: 0.0
type: LocalParameter

324875
stoichiometry: 1.0
species: 377757
type: SpeciesReference

307654
stoichiometry: 1.0
species: 378065
type: SpeciesReference

380904
units: 304591
value: 0.0
type: LocalParameter

380311
units: 304591
value: 0.0
type: LocalParameter

382350
units: 304591
value: 0.0
type: LocalParameter

381888
units: 304591
value: 0.0
type: LocalParameter

382565
units: 304591
value: 0.0
type: LocalParameter

382859
units: 304591
value: 0.0
type: LocalParameter

379833
kinetic law: 326286
reactant: 326274
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Leucineexchange
type: Reaction

379476
kinetic law: 322128
product: 322116
reactant: 322104
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: oxalatetransportoutofperoxisome
type: Reaction

382413
units: 304591
value: -1000.0
type: LocalParameter

316670
stoichiometry: 1.0
species: 378332
type: SpeciesReference

309682
stoichiometry: 1.0
species: 377580
type: SpeciesReference

381686
units: 304591
value: 0.0
type: LocalParameter

378095
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Bicarbonate
type: Species

320991
stoichiometry: 1.0
species: 378212
type: SpeciesReference

381613
units: 304591
value: 0.0
type: LocalParameter

319218
stoichiometry: 2.0
species: 378287
type: SpeciesReference

379257
product: 318180
fast: false
product: 318168
type: Reaction
kinetic law: 318192
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
reactant: 318144
name: L-lactatereversibletransportviasodiumsymport
reversible: true
reactant: 318156

383104
units: 304591
value: 0.0
type: LocalParameter

379320
product: 319340
name: Na+/K+exchangingATPase
reactant: 319303
reactant: 319291
product: 319315
notes: GENE_ASSOCIATION: (483.1 and 476.1) or (481.1 and 476.1) SUBSYSTEM: Transport, Extracellular
reversible: false
product: 319328
kinetic law: 319376
product: 319364
reactant: 319279
reactant: 319267
type: Reaction
product: 319352
fast: false

382705
units: 304591
value: 0.0
type: LocalParameter

382102
units: 304591
value: 0.0
type: LocalParameter

380421
units: 304591
value: 0.0
type: LocalParameter

321716
stoichiometry: 1.0
species: 378077
type: SpeciesReference

308221
stoichiometry: 1.0
species: 378047
type: SpeciesReference

380164
units: 304591
value: 1000.0
type: LocalParameter

383186
units: 304591
value: 0.0
type: LocalParameter

383105
units: 304591
value: 0.0
type: LocalParameter

311507
stoichiometry: 1.0
species: 378077
type: SpeciesReference

381531
units: 304591
value: 0.0
type: LocalParameter

382777
units: 304591
value: 0.0
type: LocalParameter

323801
stoichiometry: 1.0
species: 377700
type: SpeciesReference

379722
kinetic law: 325395
reactant: 325383
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
name: 13-cis-oxo-retinoicaciddemand
type: Reaction

382415
units: 304591
value: 1000.0
type: LocalParameter

308425
stoichiometry: 1.0
species: 378215
type: SpeciesReference

377874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Dehydroascorbate
type: Species

383185
units: 304591
value: 0.0
type: LocalParameter

378834
type: Reaction
product: 309488
reversible: false
notes: GENE_ASSOCIATION: (6647.1) SUBSYSTEM: ROS Detoxification
reactant: 309476
reactant: 309464
product: 309500
kinetic law: 309512
name: superoxidedismutase
fast: false

380648
units: 304591
value: 0.0
type: LocalParameter

323873
stoichiometry: 1.0
species: 377805
type: SpeciesReference

324031
stoichiometry: 1.0
species: 378125
type: SpeciesReference

383106
units: 304591
value: 0.0
type: LocalParameter

380167
units: 304591
value: 0.0
type: LocalParameter

322419
stoichiometry: 1.0
species: 377793
type: SpeciesReference

305692
stoichiometry: 1.0
species: 378227
type: SpeciesReference

382703
units: 304591
value: 1000.0
type: LocalParameter

305988
stoichiometry: 1.0
species: 377724
type: SpeciesReference

311372
stoichiometry: 1.0
species: 377984
type: SpeciesReference

380645
units: 304591
value: -1000.0
type: LocalParameter

310090
stoichiometry: 1.0
species: 378083
type: SpeciesReference

307812
stoichiometry: 1.0
species: 377832
type: SpeciesReference

377871
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Dihydroxyacetone phosphate
type: Species

309954
stoichiometry: 1.0
species: 377589
type: SpeciesReference

310683
stoichiometry: 2.0
species: 377917
type: SpeciesReference

307546
stoichiometry: 1.0
species: 377817
type: SpeciesReference

312074
stoichiometry: 1.0
species: 377700
type: SpeciesReference

314750
stoichiometry: 1.0
species: 377757
type: SpeciesReference

383184
units: 304591
value: 0.0
type: LocalParameter

382417
units: 304591
value: 0.0
type: LocalParameter

378831
fast: false
notes: GENE_ASSOCIATION: (56848.1) SUBSYSTEM: Sphingolipid Metabolism
reactant: 309392
reactant: 309404
product: 309428
reversible: false
product: 309416
kinetic law: 309452
type: Reaction
product: 309440

383107
units: 304591
value: -1000.0
type: LocalParameter

378795
kinetic law: 308763
reversible: false
reactant: 308727
notes: GENE_ASSOCIATION: (51.1) or (51.2) SUBSYSTEM: Fatty Acid Metabolism
product: 308751
fast: false
type: Reaction
product: 308739
name: acyl-CoAoxidase(hexadecanoyl-CoA),peroxisomal
reactant: 308715

382775
units: 304591
value: 0.0
type: LocalParameter

379533
kinetic law: 323082
product: 323070
reactant: 323058
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: ethanolreversibleperoxisomaltransport
type: Reaction

326419
stoichiometry: 1.0
species: 377898
type: SpeciesReference

381261
units: 304591
value: 0.0
type: LocalParameter

379725
kinetic law: 325419
reactant: 325407
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Urateexchange
type: Reaction

326081
stoichiometry: 1.0
species: 378248
type: SpeciesReference

382100
units: 304591
value: 1000.0
type: LocalParameter

306156
stoichiometry: 1.0
species: 377769
type: SpeciesReference

308377
stoichiometry: 1.0
species: 377838
type: SpeciesReference

381779
units: 304591
value: 1000.0
type: LocalParameter

380981
units: 304591
value: 0.0
type: LocalParameter

326563
stoichiometry: 1.0
species: 377622
type: SpeciesReference

321824
stoichiometry: 1.0
species: 378242
type: SpeciesReference

323022
stoichiometry: 1.0
species: 377886
type: SpeciesReference

383183
units: 304591
value: -1000.0
type: LocalParameter

317915
stoichiometry: 1.0
species: 378302
type: SpeciesReference

381880
units: 304591
value: 0.0
type: LocalParameter

315535
stoichiometry: 1.0
species: 377993
type: SpeciesReference

319436
stoichiometry: 1.0
species: 378074
type: SpeciesReference

315219
stoichiometry: 1.0
species: 377966
type: SpeciesReference

318591
stoichiometry: 3.0
species: 378206
type: SpeciesReference

378792
kinetic law: 308703
product: 308691
reactant: 308679
notes: GENE_ASSOCIATION: (6523.1) or (8170.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: Ureatransportviafacilitatediffusion
type: Reaction

378621
reactant: 305462
reactant: 305449
type: Reaction
kinetic law: 305498
fast: false
product: 305486
notes: GENE_ASSOCIATION: (10840.1) SUBSYSTEM: Fatty Acid Metabolism
name: formatedehydrogenase
product: 305474
reversible: false

379530
reactant: 322998
reversible: false
reactant: 323010
product: 323022
kinetic law: 323046
type: Reaction
product: 323034
notes: GENE_ASSOCIATION: SUBSYSTEM: Pyrimidine Catabolism
fast: false
name: 2-deoxy-D-ribose1-phosphatephosphorylase

378461
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphinganine 1-phosphate
type: Species

381909
units: 304591
value: -1000.0
type: LocalParameter

321039
stoichiometry: 1.0
species: 378428
type: SpeciesReference

383182
units: 304591
value: 0.0
type: LocalParameter

380160
units: 304591
value: 0.0
type: LocalParameter

382771
units: 304591
value: -1000.0
type: LocalParameter

325888
stoichiometry: 1.0
species: 378458
type: SpeciesReference

381776
units: 304591
value: 0.0
type: LocalParameter

380425
units: 304591
value: -1000.0
type: LocalParameter

380768
units: 304591
value: 1000.0
type: LocalParameter

381881
units: 304591
value: -1000.0
type: LocalParameter

381268
units: 304591
value: 1000.0
type: LocalParameter

379254
kinetic law: 318132
product: 318120
reactant: 318108
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion
type: Reaction

382708
units: 304591
value: 0.0
type: LocalParameter

304747
stoichiometry: 1.0
species: 377905
type: SpeciesReference

316103
stoichiometry: 1.0
species: 378080
type: SpeciesReference

317999
stoichiometry: 1.0
species: 377709
type: SpeciesReference

381908
units: 304591
value: 0.0
type: LocalParameter

382773
units: 304591
value: 1000.0
type: LocalParameter

379470
reactant: 322006
name: catalaseA,peroxisomal(ethanol)
product: 322043
reversible: false
product: 322030
notes: GENE_ASSOCIATION: (847.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
type: Reaction
kinetic law: 322055
reactant: 322018

382419
units: 304591
value: 0.0
type: LocalParameter

383100
units: 304591
value: 0.0
type: LocalParameter

381777
units: 304591
value: -1000.0
type: LocalParameter

383181
units: 304591
value: 0.0
type: LocalParameter

382060
units: 304591
value: 0.0
type: LocalParameter

382707
units: 304591
value: 0.0
type: LocalParameter

381265
units: 304591
value: -1000.0
type: LocalParameter

305764
stoichiometry: 1.0
species: 378434
type: SpeciesReference

314055
stoichiometry: 1.0
species: 378338
type: SpeciesReference

383102
units: 304591
value: 0.0
type: LocalParameter

383101
units: 304591
value: 0.0
type: LocalParameter

378837
kinetic law: 309560
product: 309548
product: 309536
reactant: 309524
notes: GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (229.1) SUBSYSTEM: Fructose and Mannose Metabolism
fast: false
reversible: true
name: D-Fructose1-phosphateD-glyceraldehyde-3-phosphate-lyase
type: Reaction

381264
units: 304591
value: 0.0
type: LocalParameter

381774
units: 304591
value: 0.0
type: LocalParameter

322504
stoichiometry: 1.0
species: 378311
type: SpeciesReference

311251
stoichiometry: 1.0
species: 378077
type: SpeciesReference

383180
units: 304591
value: 0.0
type: LocalParameter

311191
stoichiometry: 1.0
species: 378338
type: SpeciesReference

378624
reactant: 305510
product: 305559
name: L-lactatedehydrogenase
kinetic law: 305571
reversible: true
product: 305535
notes: GENE_ASSOCIATION: (3945.1) or (3945.1 and 3939.1) or (3939.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 305547
reactant: 305523
fast: false
type: Reaction

383103
units: 304591
value: -1000.0
type: LocalParameter

382770
units: 304591
value: 0.0
type: LocalParameter

381801
units: 304591
value: 0.0
type: LocalParameter

380161
units: 304591
value: -1000.0
type: LocalParameter

377942
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: GDP
type: Species

380424
units: 304591
value: 0.0
type: LocalParameter

309730
stoichiometry: 1.0
species: 378023
type: SpeciesReference

380751
units: 304591
value: 0.0
type: LocalParameter

381031
units: 304591
value: 0.0
type: LocalParameter

380811
units: 304591
value: 0.0
type: LocalParameter

326178
stoichiometry: 1.0
species: 378407
type: SpeciesReference

382623
units: 304591
value: 0.0
type: LocalParameter

378464
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphinganine 1-phosphate
type: Species

377673
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetyl-CoA
type: Species

382109
units: 304591
value: 0.0
type: LocalParameter

380010
units: 304591
value: 0.0
type: LocalParameter

382051
units: 304591
value: 1000.0
type: LocalParameter

310453
stoichiometry: 1.0
species: 378221
type: SpeciesReference

305462
stoichiometry: 1.0
species: 378212
type: SpeciesReference

379302
kinetic law: 319037
product: 319025
reactant: 319013
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: glucuronateendoplasmicreticulartransport
type: Reaction

381068
units: 304591
value: 1000.0
type: LocalParameter

381245
units: 304591
value: 0.0
type: LocalParameter

382624
units: 304591
value: -1000.0
type: LocalParameter

304879
stoichiometry: 1.0
species: 378077
type: SpeciesReference

378579
kinetic law: 304711
product: 304699
product: 304687
reactant: 304675
notes: GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (229.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: fructose-bisphosphatealdolase
type: Reaction

379029
fast: false
notes: GENE_ASSOCIATION: (4952.1) or (4952.2) SUBSYSTEM: Inositol Phosphate Metabolism
product: 313779
reactant: 313767
reversible: false
name: phosphatidylinositol-4,5-bisphosphate5-phosphatase
kinetic law: 313803
type: Reaction
reactant: 313754
product: 313791

380011
units: 304591
value: 0.0
type: LocalParameter

312619
stoichiometry: 1.0
species: 378554
type: SpeciesReference

377700
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: ADP
type: Species

306493
stoichiometry: 1.0
species: 378116
type: SpeciesReference

382792
units: 304591
value: -1000.0
type: LocalParameter

312292
stoichiometry: 1.0
species: 378086
type: SpeciesReference

309295
stoichiometry: 1.0
species: 377787
type: SpeciesReference

378615
type: Reaction
reversible: true
product: 305365
fast: false
reactant: 305341
notes: GENE_ASSOCIATION: (7086.1) SUBSYSTEM: Pentose Phosphate Pathway
product: 305353
reactant: 305329
name: transketolase
kinetic law: 305377

381034
units: 304591
value: 0.0
type: LocalParameter

379305
kinetic law: 319074
product: 319062
reactant: 319049
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: false
name: L-gulonateendoplasmicreticularexport
type: Reaction

381248
units: 304591
value: 1000.0
type: LocalParameter

314593
stoichiometry: 1.0
species: 377598
type: SpeciesReference

378576
kinetic law: 304663
product: 304651
product: 304639
reactant: 304627
notes: GENE_ASSOCIATION: (2023.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: enolase
type: Reaction

382621
units: 304591
value: 0.0
type: LocalParameter

319013
stoichiometry: 1.0
species: 377960
type: SpeciesReference

381325
units: 304591
value: -1000.0
type: LocalParameter

382910
units: 304591
value: 0.0
type: LocalParameter

305535
stoichiometry: 1.0
species: 378077
type: SpeciesReference

380014
units: 304591
value: 1000.0
type: LocalParameter

381929
units: 304591
value: 0.0
type: LocalParameter

318639
stoichiometry: 1.0
species: 378209
type: SpeciesReference

382791
units: 304591
value: 0.0
type: LocalParameter

306542
stoichiometry: 1.0
species: 377730
type: SpeciesReference

380978
units: 304591
value: 1000.0
type: LocalParameter

382053
units: 304591
value: 0.0
type: LocalParameter

380651
units: 304591
value: 0.0
type: LocalParameter

380814
units: 304591
value: 0.0
type: LocalParameter

316803
stoichiometry: 1.0
species: 378209
type: SpeciesReference

307908
stoichiometry: 1.0
species: 378080
type: SpeciesReference

381324
units: 304591
value: 0.0
type: LocalParameter

315862
stoichiometry: 1.0
species: 377993
type: SpeciesReference

377676
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377552
name: Acetyl-CoA
type: Species

317405
stoichiometry: 1.0
species: 377951
type: SpeciesReference

377781
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Calcium
type: Species

382911
units: 304591
value: 0.0
type: LocalParameter

308775
stoichiometry: 1.0
species: 377936
type: SpeciesReference

380654
units: 304591
value: 0.0
type: LocalParameter

380815
units: 304591
value: 0.0
type: LocalParameter

311057
stoichiometry: 1.0
species: 378464
type: SpeciesReference

322298
stoichiometry: 1.0
species: 377574
type: SpeciesReference

320437
stoichiometry: 1.0
species: 378353
type: SpeciesReference

383199
units: 304591
value: -1000.0
type: LocalParameter

379026
product: 313718
notes: GENE_ASSOCIATION: (5297.1) SUBSYSTEM: Glycerophospholipid Metabolism
fast: false
product: 313706
reactant: 313694
product: 313730
reactant: 313682
name: phosphatidylinositol4-kinase
reversible: false
kinetic law: 313743
type: Reaction

321341
stoichiometry: 1.0
species: 378296
type: SpeciesReference

382105
units: 304591
value: 0.0
type: LocalParameter

316055
stoichiometry: 1.0
species: 378143
type: SpeciesReference

377889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: L-erythro-4-Hydroxyglutamate
type: Species

316899
stoichiometry: 1.0
species: 378533
type: SpeciesReference

326322
stoichiometry: 1.0
species: 378143
type: SpeciesReference

382168
units: 304591
value: 0.0
type: LocalParameter

309210
stoichiometry: 1.0
species: 377987
type: SpeciesReference

324249
stoichiometry: 1.0
species: 378512
type: SpeciesReference

382055
units: 304591
value: 0.0
type: LocalParameter

377679
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Acetol
type: Species

308836
stoichiometry: 1.0
species: 378218
type: SpeciesReference

381927
units: 304591
value: 0.0
type: LocalParameter

378840
type: Reaction
reactant: 309584
kinetic law: 309620
fast: false
reversible: false
name: ADP/ATPtransporter,mitochondrial
product: 309596
product: 309608
reactant: 309572
notes: GENE_ASSOCIATION: (291.1) or (293.1) or (292.1) SUBSYSTEM: Transport, Mitochondrial

382628
units: 304591
value: 0.0
type: LocalParameter

379239
product: 317939
fast: false
kinetic law: 317951
reactant: 317903
type: Reaction
name: oxalatetransportviabicarbonatecountertransport
notes: GENE_ASSOCIATION: (1836.1) SUBSYSTEM: Transport, Extracellular
product: 317927
reactant: 317915
reversible: false

310139
stoichiometry: 1.0
species: 378065
type: SpeciesReference

378467
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphinganine
type: Species

378575
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
type: Species

307063
stoichiometry: 1.0
species: 378059
type: SpeciesReference

382104
units: 304591
value: 0.0
type: LocalParameter

382913
units: 304591
value: 13.5135135135135
type: LocalParameter

317153
stoichiometry: 3.0
species: 378092
type: SpeciesReference

322733
stoichiometry: 1.0
species: 378476
type: SpeciesReference

381035
units: 304591
value: 0.0
type: LocalParameter

314942
stoichiometry: 1.0
species: 378107
type: SpeciesReference

382056
units: 304591
value: -1000.0
type: LocalParameter

308886
stoichiometry: 1.0
species: 377607
type: SpeciesReference

307317
stoichiometry: 1.0
species: 377911
type: SpeciesReference

305134
stoichiometry: 1.0
species: 377700
type: SpeciesReference

319592
stoichiometry: 1.0
species: 377871
type: SpeciesReference

380975
units: 304591
value: 0.0
type: LocalParameter

378572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
type: Species

383109
units: 304591
value: 0.0
type: LocalParameter

311239
stoichiometry: 1.0
species: 377559
type: SpeciesReference

313923
stoichiometry: 1.0
species: 378308
type: SpeciesReference

381321
units: 304591
value: 0.0
type: LocalParameter

320643
stoichiometry: 1.0
species: 378077
type: SpeciesReference

311844
stoichiometry: 1.0
species: 378083
type: SpeciesReference

382914
units: 304591
value: 0.0
type: LocalParameter

381038
units: 304591
value: 1000.0
type: LocalParameter

382107
units: 304591
value: 1000.0
type: LocalParameter

378618
reversible: true
name: transketolase
reactant: 305389
type: Reaction
fast: false
product: 305425
kinetic law: 305437
notes: GENE_ASSOCIATION: (7086.1) SUBSYSTEM: Pentose Phosphate Pathway
reactant: 305401
product: 305413

380818
units: 304591
value: 1000.0
type: LocalParameter

322140
stoichiometry: 1.0
species: 378005
type: SpeciesReference

380655
units: 304591
value: -1000.0
type: LocalParameter

380974
units: 304591
value: 0.0
type: LocalParameter

381925
units: 304591
value: 1000.0
type: LocalParameter

383108
units: 304591
value: 13.5135135135135
type: LocalParameter

380017
units: 304591
value: 0.0
type: LocalParameter

382626
units: 304591
value: 1000.0
type: LocalParameter

382915
units: 304591
value: 0.0
type: LocalParameter

382058
units: 304591
value: 1000.0
type: LocalParameter

379023
notes: GENE_ASSOCIATION: (8396.1) or (8396.2) SUBSYSTEM: Glycerophospholipid Metabolism
type: Reaction
fast: false
product: 313646
name: phosphatidylinositol4-phosphate5-kinase
product: 313634
reactant: 313610
reversible: false
kinetic law: 313670
reactant: 313622
product: 313658

378359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Diphosphate
type: Species

382916
units: 304591
value: 0.0
type: LocalParameter

382214
units: 304591
value: 0.0
type: LocalParameter

315644
stoichiometry: 1.0
species: 377993
type: SpeciesReference

382843
units: 304591
value: 13.5135135135135
type: LocalParameter

378152
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Lactaldehyde
type: Species

310248
stoichiometry: 1.0
species: 378215
type: SpeciesReference

381922
units: 304591
value: 0.0
type: LocalParameter

320328
stoichiometry: 1.0
species: 378200
type: SpeciesReference

383291
units: 304591
value: -1000.0
type: LocalParameter

308946
stoichiometry: 1.0
species: 378446
type: SpeciesReference

312364
stoichiometry: 1.0
species: 377823
type: SpeciesReference

380924
units: 304591
value: 0.0
type: LocalParameter

382163
units: 304591
value: 1000.0
type: LocalParameter

382560
units: 304591
value: 0.0
type: LocalParameter

380545
units: 304591
value: -1000.0
type: LocalParameter

380398
units: 304591
value: 1000.0
type: LocalParameter

378684
notes: GENE_ASSOCIATION: (4190.1) SUBSYSTEM: Citric Acid Cycle
kinetic law: 306843
name: malatedehydrogenase
type: Reaction
product: 306819
reactant: 306795
product: 306831
product: 306807
reversible: true
reactant: 306783
fast: false

379173
kinetic law: 316683
product: 316670
reactant: 316658
notes: GENE_ASSOCIATION: (124935.1) or (117247.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
type: Reaction

379455
product: 321776
reactant: 321704
product: 321752
name: ProstaglandinG/Hsynthase
kinetic law: 321788
reactant: 321740
product: 321764
type: Reaction
notes: GENE_ASSOCIATION: (5743.1) SUBSYSTEM: Eicosanoid Metabolism
reversible: false
fast: false
reactant: 321716
reactant: 321728

378221
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide - reduced
type: Species

322697
stoichiometry: 1.0
species: 378347
type: SpeciesReference

321451
stoichiometry: 1.0
species: 378266
type: SpeciesReference

382338
units: 304591
value: 1000.0
type: LocalParameter

382917
units: 304591
value: 13.5135135135135
type: LocalParameter

309102
stoichiometry: 1.0
species: 378266
type: SpeciesReference

381475
units: 304591
value: -1000.0
type: LocalParameter

315014
stoichiometry: 1.0
species: 378059
type: SpeciesReference

377787
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: cAMP
type: Species

381923
units: 304591
value: -1000.0
type: LocalParameter

378080
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: H+
type: Species

383290
units: 304591
value: 0.0
type: LocalParameter

377709
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: adrenic acid
type: Species

380544
units: 304591
value: 0.0
type: LocalParameter

378729
kinetic law: 307630
product: 307618
reactant: 307606
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: o2transport(diffusion)
type: Reaction

380925
units: 304591
value: 0.0
type: LocalParameter

309307
stoichiometry: 1.0
species: 378359
type: SpeciesReference

379458
notes: GENE_ASSOCIATION: (5743.1) SUBSYSTEM: Eicosanoid Metabolism
name: ProstaglandinG/Hsynthase
type: Reaction
product: 321848
reactant: 321800
reactant: 321812
product: 321872
fast: false
product: 321860
reactant: 321824
reversible: false
kinetic law: 321885
reactant: 321836

322841
stoichiometry: 1.0
species: 377778
type: SpeciesReference

379020
reversible: true
type: Reaction
reactant: 313561
notes: GENE_ASSOCIATION: (285216.1) or (80068.1) SUBSYSTEM: Folate Metabolism
reactant: 313549
product: 313573
kinetic law: 313598
product: 313585
fast: false

382216
units: 304591
value: 0.0
type: LocalParameter

382563
units: 304591
value: 1000.0
type: LocalParameter

320087
stoichiometry: 1.0
species: 378077
type: SpeciesReference

326395
stoichiometry: 1.0
species: 377981
type: SpeciesReference

317333
stoichiometry: 2.0
species: 378209
type: SpeciesReference

304675
stoichiometry: 1.0
species: 377914
type: SpeciesReference

378224
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Nicotinamide adenine dinucleotide - reduced
type: Species

317636
stoichiometry: 1.0
species: 378488
type: SpeciesReference

378681
notes: GENE_ASSOCIATION: (8802.1 and 8801.1) SUBSYSTEM: Citric Acid Cycle
product: 306735
reactant: 306723
reversible: true
kinetic law: 306771
product: 306747
type: Reaction
reactant: 306699
product: 306759
reactant: 306711
name: Succinate--CoAligase(GDP-forming)
fast: false

324803
stoichiometry: 1.0
species: 377966
type: SpeciesReference

382845
units: 304591
value: 0.0
type: LocalParameter

381478
units: 304591
value: 1000.0
type: LocalParameter

379680
kinetic law: 325055
reactant: 325043
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

305243
stoichiometry: 1.0
species: 378551
type: SpeciesReference

381920
units: 304591
value: 0.0
type: LocalParameter

318578
stoichiometry: 1.0
species: 377784
type: SpeciesReference

383210
units: 304591
value: 0.0
type: LocalParameter

382165
units: 304591
value: 0.0
type: LocalParameter

311736
stoichiometry: 1.0
species: 378218
type: SpeciesReference

382167
units: 304591
value: 0.0
type: LocalParameter

378155
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Lactaldehyde
type: Species

383212
units: 304591
value: 13.5135135135135
type: LocalParameter

382919
units: 304591
value: 0.0
type: LocalParameter

378951
kinetic law: 312182
product: 312170
reactant: 312158
notes: GENE_ASSOCIATION: (5740.1) SUBSYSTEM: Eicosanoid Metabolism
fast: false
reversible: true
name: ProstaglandinI2synthase
type: Reaction

315910
stoichiometry: 2.0
species: 377850
type: SpeciesReference

381600
units: 304591
value: 0.0
type: LocalParameter

308089
stoichiometry: 1.0
species: 378026
type: SpeciesReference

306916
stoichiometry: 1.0
species: 378200
type: SpeciesReference

379849
kinetic law: 326431
reactant: 326419
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Ethanolexchange
type: Reaction

382561
units: 304591
value: 0.0
type: LocalParameter

383211
units: 304591
value: -1000.0
type: LocalParameter

381061
units: 304591
value: 0.0
type: LocalParameter

313706
stoichiometry: 1.0
species: 377700
type: SpeciesReference

383213
units: 304591
value: 0.0
type: LocalParameter

316911
stoichiometry: 1.0
species: 378059
type: SpeciesReference

382335
units: 304591
value: 0.0
type: LocalParameter

379176
kinetic law: 316719
product: 316707
reactant: 316695
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
type: Reaction

378687
kinetic law: 306892
product: 306880
reactant: 306868
reactant: 306855
notes: GENE_ASSOCIATION: (2271.1) SUBSYSTEM: Citric Acid Cycle
fast: false
reversible: true
name: fumarase,mitochondrial
type: Reaction

378726
kinetic law: 307594
product: 307582
reactant: 307570
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: CO2transporterviadiffusion
type: Reaction

305305
stoichiometry: 1.0
species: 377905
type: SpeciesReference

380541
units: 304591
value: 0.0
type: LocalParameter

383295
units: 304591
value: -1000.0
type: LocalParameter

379308
kinetic law: 319110
product: 319098
reactant: 319086
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: O2transport,peroxisomal
type: Reaction

318853
stoichiometry: 1.0
species: 377811
type: SpeciesReference

323221
stoichiometry: 1.0
species: 378152
type: SpeciesReference

322359
stoichiometry: 1.0
species: 378338
type: SpeciesReference

320799
stoichiometry: 1.0
species: 377649
type: SpeciesReference

377706
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: adrenic acid
type: Species

323512
stoichiometry: 1.0
species: 378569
type: SpeciesReference

320835
stoichiometry: 1.0
species: 377862
type: SpeciesReference

382840
units: 304591
value: 0.0
type: LocalParameter

378011
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Oxidized glutathione
type: Species

382217
units: 304591
value: -1000.0
type: LocalParameter

383214
units: 304591
value: 0.0
type: LocalParameter

304988
stoichiometry: 1.0
species: 378077
type: SpeciesReference

377670
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Acetaldehyde
type: Species

310344
stoichiometry: 1.0
species: 378497
type: SpeciesReference

380921
units: 304591
value: 0.0
type: LocalParameter

383294
units: 304591
value: 0.0
type: LocalParameter

382160
units: 304591
value: 0.0
type: LocalParameter

322200
stoichiometry: 1.0
species: 378422
type: SpeciesReference

320571
stoichiometry: 1.0
species: 377643
type: SpeciesReference

318530
stoichiometry: 1.0
species: 378506
type: SpeciesReference

382841
units: 304591
value: 0.0
type: LocalParameter

310985
stoichiometry: 0.02
species: 378284
type: SpeciesReference

377784
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Calcium
type: Species

378723
fast: false
reactant: 307510
notes: GENE_ASSOCIATION: (2571.1) or (2571.2) SUBSYSTEM: Glutamate metabolism
name: GlutamateDecarboxylase
kinetic law: 307558
type: Reaction
reversible: false
reactant: 307522
product: 307534
product: 307546

378014
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Oxidized glutathione
type: Species

378158
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: L-Leucine
type: Species

314484
stoichiometry: 1.0
species: 377601
type: SpeciesReference

383215
units: 304591
value: -1000.0
type: LocalParameter

381064
units: 304591
value: 0.0
type: LocalParameter

382161
units: 304591
value: 0.0
type: LocalParameter

309186
stoichiometry: 1.0
species: 378254
type: SpeciesReference

383293
units: 304591
value: 0.0
type: LocalParameter

306432
stoichiometry: 1.0
species: 378416
type: SpeciesReference

382219
units: 304591
value: 1000.0
type: LocalParameter

379179
product: 316767
type: Reaction
product: 316755
reversible: true
reactant: 316743
notes: GENE_ASSOCIATION: (6540.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 316779
fast: false
reactant: 316731

379683
kinetic law: 325079
reactant: 325067
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

314387
stoichiometry: 1.0
species: 378077
type: SpeciesReference

378227
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Nicotinamide adenine dinucleotide phosphate
type: Species

383216
units: 304591
value: 0.0
type: LocalParameter

378356
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Palmitoyl-CoA (n-C16:0CoA)
type: Species

382336
units: 304591
value: 0.0
type: LocalParameter

381328
units: 304591
value: 1000.0
type: LocalParameter

381065
units: 304591
value: 0.0
type: LocalParameter

383292
units: 304591
value: 0.0
type: LocalParameter

308209
stoichiometry: 2.0
species: 378017
type: SpeciesReference

323182
stoichiometry: 1.0
species: 378482
type: SpeciesReference

313851
stoichiometry: 2.0
species: 378062
type: SpeciesReference

377703
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: ADP
type: Species

380861
units: 304591
value: 0.0
type: LocalParameter

380170
units: 304591
value: 0.0
type: LocalParameter

381818
units: 304591
value: -1000.0
type: LocalParameter

383083
units: 304591
value: -1000.0
type: LocalParameter

381692
units: 304591
value: 0.0
type: LocalParameter

325311
stoichiometry: 1.0
species: 378296
type: SpeciesReference

381895
units: 304591
value: 0.0
type: LocalParameter

381782
units: 304591
value: 0.0
type: LocalParameter

383298
units: 304591
value: 0.0
type: LocalParameter

308655
stoichiometry: 1.0
species: 378404
type: SpeciesReference

307111
stoichiometry: 1.0
species: 378266
type: SpeciesReference

317855
stoichiometry: 1.0
species: 378092
type: SpeciesReference

382556
units: 304591
value: 1000.0
type: LocalParameter

378720
reactant: 307450
name: alcoholdehydrogenase,forwardrxn(ethanol->acetaldehyde)
reactant: 307438
kinetic law: 307498
product: 307486
notes: GENE_ASSOCIATION: (128.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
product: 307462
type: Reaction
fast: false
product: 307474
reversible: false

381548
units: 304591
value: 1000.0
type: LocalParameter

383206
units: 304591
value: 0.0
type: LocalParameter

381606
units: 304591
value: 0.0
type: LocalParameter

378149
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: L-Lactate
type: Species

381781
units: 304591
value: 0.0
type: LocalParameter

378362
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Diphosphate
type: Species

383005
units: 304591
value: 0.0
type: LocalParameter

321897
stoichiometry: 1.0
species: 378353
type: SpeciesReference

381704
units: 304591
value: 0.0
type: LocalParameter

383110
units: 304591
value: 0.0
type: LocalParameter

380864
units: 304591
value: 0.0
type: LocalParameter

381817
units: 304591
value: 0.0
type: LocalParameter

381693
units: 304591
value: -1000.0
type: LocalParameter

378957
kinetic law: 312256
product: 312244
reactant: 312231
notes: GENE_ASSOCIATION: (2544.1) SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: phosphatetransport,endoplasmicreticulum
type: Reaction

325696
stoichiometry: 1.0
species: 378020
type: SpeciesReference

383082
units: 304591
value: 0.0
type: LocalParameter

383299
units: 304591
value: -1000.0
type: LocalParameter

381783
units: 304591
value: 0.0
type: LocalParameter

382342
units: 304591
value: 0.0
type: LocalParameter

383205
units: 304591
value: 0.0
type: LocalParameter

379674
kinetic law: 325007
reactant: 324995
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

315439
stoichiometry: 1.0
species: 377996
type: SpeciesReference

382343
units: 304591
value: 0.0
type: LocalParameter

311408
stoichiometry: 1.0
species: 377715
type: SpeciesReference

316199
stoichiometry: 1.0
species: 377769
type: SpeciesReference

383006
units: 304591
value: 0.0
type: LocalParameter

316477
stoichiometry: 3.0
species: 378206
type: SpeciesReference

383085
units: 304591
value: 0.0
type: LocalParameter

380328
units: 304591
value: 1000.0
type: LocalParameter

314690
stoichiometry: 1.0
species: 377601
type: SpeciesReference

323440
stoichiometry: 1.0
species: 378563
type: SpeciesReference

380865
units: 304591
value: -1000.0
type: LocalParameter

383002
units: 304591
value: 0.0
type: LocalParameter

381897
units: 304591
value: 1000.0
type: LocalParameter

311953
stoichiometry: 1.0
species: 377972
type: SpeciesReference

312134
stoichiometry: 1.0
species: 378386
type: SpeciesReference

383190
units: 304591
value: 0.0
type: LocalParameter

383296
units: 304591
value: 0.0
type: LocalParameter

315316
stoichiometry: 1.0
species: 378449
type: SpeciesReference

381608
units: 304591
value: 0.0
type: LocalParameter

305825
stoichiometry: 1.0
species: 378416
type: SpeciesReference

378005
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Glycolate
type: Species

383208
units: 304591
value: 0.0
type: LocalParameter

379840
kinetic law: 326359
reactant: 326346
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Isoleucineexchange
type: Reaction

382558
units: 304591
value: 0.0
type: LocalParameter

383003
units: 304591
value: 0.0
type: LocalParameter

325937
stoichiometry: 1.0
species: 377996
type: SpeciesReference

381695
units: 304591
value: 1000.0
type: LocalParameter

379461
kinetic law: 321921
product: 321909
reactant: 321897
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: fattyacidintracellulartransport
type: Reaction

309392
stoichiometry: 1.0
species: 377769
type: SpeciesReference

305025
stoichiometry: 1.0
species: 378200
type: SpeciesReference

325720
stoichiometry: 1.0
species: 377733
type: SpeciesReference

383084
units: 304591
value: 13.5135135135135
type: LocalParameter

312861
stoichiometry: 2.0
species: 378047
type: SpeciesReference

381481
units: 304591
value: 0.0
type: LocalParameter

312545
stoichiometry: 1.0
species: 378236
type: SpeciesReference

381815
units: 304591
value: 0.0
type: LocalParameter

381702
units: 304591
value: 1000.0
type: LocalParameter

383297
units: 304591
value: 0.0
type: LocalParameter

381785
units: 304591
value: 1000.0
type: LocalParameter

322624
stoichiometry: 1.0
species: 378317
type: SpeciesReference

377957
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: D-Glucose
type: Species

319845
stoichiometry: 1.0
species: 377933
type: SpeciesReference

378089
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: H+
type: Species

378365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: pristanic acid
type: Species

383207
units: 304591
value: -1000.0
type: LocalParameter

382345
units: 304591
value: 1000.0
type: LocalParameter

314151
stoichiometry: 1.0
species: 377628
type: SpeciesReference

383004
units: 304591
value: 13.5135135135135
type: LocalParameter

306276
stoichiometry: 1.0
species: 377856
type: SpeciesReference

382490
units: 304591
value: -1000.0
type: LocalParameter

382551
units: 304591
value: 0.0
type: LocalParameter

308595
stoichiometry: 1.0
species: 378377
type: SpeciesReference

381899
units: 304591
value: 0.0
type: LocalParameter

313646
stoichiometry: 1.0
species: 378077
type: SpeciesReference

383087
units: 304591
value: -1000.0
type: LocalParameter

309817
stoichiometry: 1.0
species: 378077
type: SpeciesReference

315280
stoichiometry: 1.0
species: 377993
type: SpeciesReference

380548
units: 304591
value: 1000.0
type: LocalParameter

378786
reactant: 308570
fast: false
type: Reaction
name: Na+/Proline-Lsymporter
product: 308595
reversible: false
reactant: 308558
kinetic law: 308607
product: 308583
notes: GENE_ASSOCIATION: (54407.1) SUBSYSTEM: Transport, Extracellular

383009
units: 304591
value: 0.0
type: LocalParameter

381697
units: 304591
value: 0.0
type: LocalParameter

381544
units: 304591
value: 0.0
type: LocalParameter

378891
notes: GENE_ASSOCIATION: (498.2 and 509.1 and 513.2 and 506.1 and 514.1 or 513.1 and 506.1 and 498.3 and 509.2 and 514.1 or 513.2 and 498.1 and 506.1 and 509.2 and 514.1 or 513.1 and 509.1 and 506.1 and 498.3 and 514.1 or 513.1 and 509.1 and 498.1 and 514.2 and 506.1 or 513.1 and 514.2 and 506.1 and 498.3 and 509.2 or 513.1 and 509.1 and 498.1 and 506.1 and 514.1 or 513.1 and 509.1 and 514.2 and 506.1 and 498.3 or 513.2 and 506.1 and 498.3 and 509.2 and 514.1 or 498.2 and 513.2 and 514.2 and 506.1 and 509.2 or 513.1 and 498.2 and 506.1 and 509.2 and 514.1 or 513.1 and 498.1 and 514.2 and 506.1 and 509.2 or 509.1 and 513.2 and 498.1 and 506.1 and 514.1 or 513.1 and 498.2 and 509.1 and 506.1 and 514.1 or 498.2 and 509.1 and 513.2 and 514.2 and 506.1 or 509.1 and 513.2 and 514.2 and 506.1 and 498.3 or 513.1 and 498.2 and 514.2 and 506.1 and 509.2 or 498.2 and 513.2 and 506.1 and 509.2 and 514.1 or 513.2 and 498.1 and 514.2 and 506.1 and 509.2 or 509.1 and 513.2 and 498.1 and 514.2 and 506.1 or 513.2 and 514.2 and 506.1 and 498.3 and 509.2 or 509.1 and 513.2 and 506.1 and 498.3 and 514.1 or 513.1 and 498.2 and 509.1 and 514.2 and 506.1) SUBSYSTEM: Oxidative Phosphorylation
product: 310828
kinetic law: 310840
reactant: 310779
reactant: 310767
fast: false
reversible: false
reactant: 310791
product: 310816
name: ATPsynthase(fourprotonsforoneATP)
product: 310803
type: Reaction

379524
kinetic law: 322913
product: 322901
reactant: 322889
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: intracellulartransport
type: Reaction

382848
units: 304591
value: 0.0
type: LocalParameter

379677
kinetic law: 325031
reactant: 325019
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: false
type: Reaction

306990
stoichiometry: 1.0
species: 378077
type: SpeciesReference

379846
kinetic law: 326407
reactant: 326395
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Glutamateexchange
type: Reaction

311494
stoichiometry: 1.0
species: 377661
type: SpeciesReference

307642
stoichiometry: 1.0
species: 377667
type: SpeciesReference

382221
units: 304591
value: 0.0
type: LocalParameter

381700
units: 304591
value: -1000.0
type: LocalParameter

380868
units: 304591
value: 1000.0
type: LocalParameter

322949
stoichiometry: 1.0
species: 378218
type: SpeciesReference

308005
stoichiometry: 1.0
species: 377661
type: SpeciesReference

383086
units: 304591
value: 0.0
type: LocalParameter

326491
stoichiometry: 1.0
species: 377751
type: SpeciesReference

378230
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: Nicotinamide adenine dinucleotide phosphate
type: Species

378083
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377549
name: H+
type: Species

381545
units: 304591
value: 0.0
type: LocalParameter

383209
units: 304591
value: 0.0
type: LocalParameter

381601
units: 304591
value: 0.0
type: LocalParameter

319206
stoichiometry: 2.0
species: 378089
type: SpeciesReference

382401
units: 304591
value: 1000.0
type: LocalParameter

378008
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377558
name: Glycolate
type: Species

379464
kinetic law: 321957
product: 321945
reactant: 321933
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: false
name: urateexportfromperoxisome
type: Reaction

382847
units: 304591
value: 0.0
type: LocalParameter

382553
units: 304591
value: 0.0
type: LocalParameter

380324
units: 304591
value: 0.0
type: LocalParameter

379527
reversible: false
name: D-Lactaldehyde:NAD+1-oxidoreductase
kinetic law: 322986
fast: false
product: 322973
reactant: 322937
type: Reaction
product: 322961
reactant: 322949
notes: GENE_ASSOCIATION: (8574.1) SUBSYSTEM: Pyruvate Metabolism
reactant: 322925

382492
units: 304591
value: 1000.0
type: LocalParameter

313441
stoichiometry: 2.0
species: 378077
type: SpeciesReference

310767
stoichiometry: 1.0
species: 377703
type: SpeciesReference

381484
units: 304591
value: 0.0
type: LocalParameter

383089
units: 304591
value: 0.0
type: LocalParameter

381699
units: 304591
value: 0.0
type: LocalParameter

381485
units: 304591
value: 0.0
type: LocalParameter

378086
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: H+
type: Species

383007
units: 304591
value: 0.0
type: LocalParameter

378690
kinetic law: 306941
product: 306928
reactant: 306916
reactant: 306904
notes: GENE_ASSOCIATION: (2739.1) SUBSYSTEM: Pyruvate Metabolism
fast: false
reversible: false
name: lactoylglutathionelyase
type: Reaction

382554
units: 304591
value: -1000.0
type: LocalParameter

381604
units: 304591
value: 1000.0
type: LocalParameter

382223
units: 304591
value: 0.0
type: LocalParameter

380325
units: 304591
value: 0.0
type: LocalParameter

382340
units: 304591
value: 0.0
type: LocalParameter

383088
units: 304591
value: 13.5135135135135
type: LocalParameter

378894
reversible: false
reactant: 310864
name: superoxidedismutase
product: 310877
product: 310889
reactant: 310852
kinetic law: 310901
fast: false
notes: GENE_ASSOCIATION: (6648.1) SUBSYSTEM: ROS Detoxification
type: Reaction

311628
stoichiometry: 1.0
species: 378077
type: SpeciesReference

378954
kinetic law: 312219
product: 312207
reactant: 312195
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Endoplasmic Reticular
fast: false
reversible: true
name: glucosetransport,endoplasmicreticulum
type: Reaction

383008
units: 304591
value: 13.5135135135135
type: LocalParameter

378789
product: 308655
reactant: 308631
fast: false
reactant: 308619
notes: GENE_ASSOCIATION: (9123.1) SUBSYSTEM: Transport, Extracellular
type: Reaction
reversible: true
product: 308643
name: pyruvatereversibletransportviaprotonsymport
kinetic law: 308667

380918
units: 304591
value: 1000.0
type: LocalParameter

379843
kinetic law: 326383
reactant: 326371
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: L-Histidineexchange
type: Reaction

379170
kinetic law: 316646
product: 316634
reactant: 316622
notes: GENE_ASSOCIATION: (124935.1) SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
type: Reaction

382224
units: 304591
value: 0.0
type: LocalParameter

382112
units: 304591
value: 0.0
type: LocalParameter

305976
stoichiometry: 1.0
species: 377712
type: SpeciesReference

305680
stoichiometry: 1.0
species: 378059
type: SpeciesReference

380808
units: 304591
value: 1000.0
type: LocalParameter

383118
units: 304591
value: 0.0
type: LocalParameter

382406
units: 304591
value: 0.0
type: LocalParameter

309464
stoichiometry: 2.0
species: 378077
type: SpeciesReference

312062
stoichiometry: 1.0
species: 377927
type: SpeciesReference

383196
units: 304591
value: 0.0
type: LocalParameter

307992
stoichiometry: 1.0
species: 377664
type: SpeciesReference

311384
stoichiometry: 1.0
species: 378065
type: SpeciesReference

377951
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: D-Glucose
type: Species

380431
units: 304591
value: 0.0
type: LocalParameter

314762
stoichiometry: 1.0
species: 378206
type: SpeciesReference

307534
stoichiometry: 1.0
species: 377619
type: SpeciesReference

377883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deamino-NAD+
type: Species

380758
units: 304591
value: 1000.0
type: LocalParameter

307800
stoichiometry: 1.0
species: 377826
type: SpeciesReference

382111
units: 304591
value: 0.0
type: LocalParameter

382494
units: 304591
value: 0.0
type: LocalParameter

381810
units: 304591
value: 0.0
type: LocalParameter

379521
product: 322853
product: 322841
fast: false
reactant: 322793
notes: GENE_ASSOCIATION: (4363.1) SUBSYSTEM: Transport, Extracellular
kinetic law: 322877
type: Reaction
product: 322829
reactant: 322805
reactant: 322817
name: bilirubinmonoglucuronidetransportMDR
product: 322865
reversible: true

381028
units: 304591
value: 1000.0
type: LocalParameter

382405
units: 304591
value: 0.0
type: LocalParameter

383119
units: 304591
value: -1000.0
type: LocalParameter

378843
kinetic law: 309670
product: 309658
product: 309645
reactant: 309632
notes: GENE_ASSOCIATION: (847.1) SUBSYSTEM: Miscellaneous
fast: false
reversible: false
name: catalaseA,peroxisomal
type: Reaction

378582
reversible: false
kinetic law: 304771
name: fructose-bisphosphatase
product: 304759
notes: GENE_ASSOCIATION: (2203.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reactant: 304735
product: 304747
type: Reaction
reactant: 304723

379248
kinetic law: 318060
product: 318048
reactant: 318036
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion
type: Reaction

382787
units: 304591
value: 1000.0
type: LocalParameter

381541
units: 304591
value: 0.0
type: LocalParameter

378783
kinetic law: 308546
product: 308533
reactant: 308521
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: coenzymeAtransport,peroxisomal
type: Reaction

314509
stoichiometry: 1.0
species: 378239
type: SpeciesReference

321812
stoichiometry: 1.0
species: 378086
type: SpeciesReference

383195
units: 304591
value: -1000.0
type: LocalParameter

380658
units: 304591
value: 1000.0
type: LocalParameter

323034
stoichiometry: 1.0
species: 378338
type: SpeciesReference

379737
kinetic law: 325516
reactant: 325503
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Bicarbonateexchange
type: Reaction

306168
stoichiometry: 1.0
species: 377939
type: SpeciesReference

308365
stoichiometry: 1.0
species: 377841
type: SpeciesReference

382114
units: 304591
value: 1000.0
type: LocalParameter

382497
units: 304591
value: -1000.0
type: LocalParameter

377805
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Citrate
type: Species

306060
stoichiometry: 1.0
species: 377700
type: SpeciesReference

319364
stoichiometry: 1.0
species: 378338
type: SpeciesReference

379245
kinetic law: 318024
product: 318012
reactant: 317999
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion
type: Reaction

383116
units: 304591
value: 13.5135135135135
type: LocalParameter

380177
units: 304591
value: 0.0
type: LocalParameter

378897
reactant: 310913
product: 310949
name: cytochromecoxidase,mitochondrialComplexIV
reactant: 310925
product: 310973
product: 310985
reversible: false
reactant: 310937
fast: false
notes: GENE_ASSOCIATION: (1351.1) and (1329.1) and (1347.1) and (1327.1) and (9167.1) and (341947.1) and (4512.1) and (1350.1) and (1349.1) and (1339.1) and (4513.1) and (9377.1) and (1345.1) and (125965.1) and (4514.1) and (170712.1) and (1346.1) and (1340.1) and (1337.1) and (84701.1) SUBSYSTEM: Oxidative Phosphorylation
type: Reaction
product: 310961
kinetic law: 310997

321704
stoichiometry: 1.0
species: 377739
type: SpeciesReference

383198
units: 304591
value: 0.0
type: LocalParameter

382496
units: 304591
value: 0.0
type: LocalParameter

382403
units: 304591
value: 0.0
type: LocalParameter

379734
kinetic law: 325491
reactant: 325479
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Oxalateexchange
type: Reaction

317781
stoichiometry: 1.0
species: 377841
type: SpeciesReference

378470
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377555
name: Sphinganine
type: Species

311519
stoichiometry: 1.0
species: 378236
type: SpeciesReference

382789
units: 304591
value: 0.0
type: LocalParameter

383117
units: 304591
value: 0.0
type: LocalParameter

323885
stoichiometry: 1.0
species: 377814
type: SpeciesReference

378846
kinetic law: 309718
product: 309706
product: 309694
reactant: 309682
notes: GENE_ASSOCIATION: (5223.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
fast: false
reversible: true
name: Diphosphoglyceromutase
type: Reaction

308437
stoichiometry: 1.0
species: 377889
type: SpeciesReference

380971
units: 304591
value: 0.0
type: LocalParameter

325479
stoichiometry: 1.0
species: 378302
type: SpeciesReference

383197
units: 304591
value: 0.0
type: LocalParameter

380434
units: 304591
value: 0.0
type: LocalParameter

381251
units: 304591
value: 0.0
type: LocalParameter

380321
units: 304591
value: 0.0
type: LocalParameter

324562
stoichiometry: 1.0
species: 378455
type: SpeciesReference

377886
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Deoxyribose
type: Species

314043
stoichiometry: 1.0
species: 378323
type: SpeciesReference

383114
units: 304591
value: 0.0
type: LocalParameter

382499
units: 304591
value: 1000.0
type: LocalParameter

319508
stoichiometry: 1.0
species: 377769
type: SpeciesReference

381890
units: 304591
value: 1000.0
type: LocalParameter

305752
stoichiometry: 1.0
species: 377769
type: SpeciesReference

383192
units: 304591
value: 13.5135135135135
type: LocalParameter

380435
units: 304591
value: -1000.0
type: LocalParameter

380754
units: 304591
value: 0.0
type: LocalParameter

378849
kinetic law: 309793
product: 309769
type: Reaction
product: 309756
notes: GENE_ASSOCIATION: (5105.1) SUBSYSTEM: Glycolysis/Gluconeogenesis
reversible: false
reactant: 309743
name: Phosphoenolpyruvatecarboxykinase(GTP)
fast: false
reactant: 309730
product: 309781

383000
units: 304591
value: 13.5135135135135
type: LocalParameter

305608
stoichiometry: 1.0
species: 378212
type: SpeciesReference

381709
units: 304591
value: 1000.0
type: LocalParameter

307703
stoichiometry: 1.0
species: 378221
type: SpeciesReference

380174
units: 304591
value: 1000.0
type: LocalParameter

383115
units: 304591
value: -1000.0
type: LocalParameter

321123
stoichiometry: 1.0
species: 378428
type: SpeciesReference

378612
reactant: 305280
kinetic law: 305317
name: transaldolase
notes: GENE_ASSOCIATION: (6888.1) SUBSYSTEM: Pentose Phosphate Pathway
reversible: true
product: 305305
fast: false
type: Reaction
product: 305292
reactant: 305268

326829
stoichiometry: 1.0
species: 377954
type: SpeciesReference

381254
units: 304591
value: 0.0
type: LocalParameter

377802
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Citrate
type: Species

381609
units: 304591
value: 0.0
type: LocalParameter

319098
stoichiometry: 1.0
species: 378278
type: SpeciesReference

383191
units: 304591
value: -1000.0
type: LocalParameter

307269
stoichiometry: 1.0
species: 378044
type: SpeciesReference

381892
units: 304591
value: 0.0
type: LocalParameter

377880
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: Deoxyinosine
type: Species

381787
units: 304591
value: 0.0
type: LocalParameter

382782
units: 304591
value: 0.0
type: LocalParameter

325188
stoichiometry: 1.0
species: 377781
type: SpeciesReference

383001
units: 304591
value: 0.0
type: LocalParameter

380755
units: 304591
value: 0.0
type: LocalParameter

381813
units: 304591
value: 1000.0
type: LocalParameter

378473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377545
name: Sphingosine
type: Species

382784
units: 304591
value: 0.0
type: LocalParameter

382408
units: 304591
value: 1000.0
type: LocalParameter

312207
stoichiometry: 1.0
species: 377957
type: SpeciesReference

377954
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 377546
name: D-Glucose
type: Species

317903
stoichiometry: 2.0
species: 378092
type: SpeciesReference

319424
stoichiometry: 1.0
species: 377990
type: SpeciesReference

381255
units: 304591
value: -1000.0
type: LocalParameter

315547
stoichiometry: 1.0
species: 377718
type: SpeciesReference

378780
kinetic law: 308509
product: 308497
reactant: 308485
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Peroxisomal
fast: false
reversible: true
name: hydrogenperoxideperoxisomaltransportviadiffusion
type: Reaction

379731
kinetic law: 325467
reactant: 325455
notes: GENE_ASSOCIATION: SUBSYSTEM:
fast: false
reversible: true
name: Methylglyoxalexchange
type: Reaction

383081
units: 304591
value: 0.0
type: LocalParameter

309743
stoichiometry: 1.0
species: 378290
type: SpeciesReference

383194
units: 304591
value: 0.0
type: LocalParameter

324779
stoichiometry: 1.0
species: 377978
type: SpeciesReference

381707
units: 304591
value: -1000.0
type: LocalParameter

380020
units: 304591
value: 0.0
type: LocalParameter

383111
units: 304591
value: -1000.0
type: LocalParameter

382785
units: 304591
value: -1000.0
type: LocalParameter

383113
units: 304591
value: 0.0
type: LocalParameter

304735
stoichiometry: 1.0
species: 378059
type: SpeciesReference

379242
kinetic law: 317987
product: 317975
reactant: 317963
notes: GENE_ASSOCIATION: SUBSYSTEM: Transport, Extracellular
fast: false
reversible: true
name: fattyacidtransportviadiffusion
type: Reaction

323970
stoichiometry: 1.0
species: 378062
type: SpeciesReference

381811
units: 304591
value: 0.0
type: LocalParameter

381789
units: 304591
value: 0.0
type: LocalParameter

381894
units: 304591
value: 0.0
type: LocalParameter

383080
units: 304591
value: 0.0
type: LocalParameter

381706
units: 304591
value: 0.0
type: LocalParameter

383193
units: 304591
value: 0.0
type: LocalParameter

312752
stoichiometry: 1.0
species: 378041
type: SpeciesReference

383112
units: 304591
value: 0.0
type: LocalParameter

380171
units: 304591
value: -1000.0
type: LocalParameter

380021
units: 304591
value: -1000.0
type: LocalParameter

380438
units: 304591
value: 1000.0
type: LocalParameter

309967
stoichiometry: 2.0
species: 378065
type: SpeciesReference