GENE_ASSOCIATION: (124637.1) GENE_LIST: 124637.1 SUBSYSTEM: Pyruvate Metabolism
L-Lactate dehydrogenase, cytosolic/mitochondrial
GENE_ASSOCIATION: (22934.1) GENE_LIST: 22934.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (117247.1) GENE_LIST: 117247.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (4522.1) or (286297.1) GENE_LIST: 286297.1 4522.1 SUBSYSTEM: Folate Metabolism
testicular 17-beta-hydroxysteroid dehydrogenase
GENE_ASSOCIATION: (3292.1) or (7923.1) GENE_LIST: 3292.1 7923.1 SUBSYSTEM: Steroid Metabolism
3',5'-cyclic-nucleotide phosphodiesterase
hydroxysteroid (17-beta) dehydrogenase 4
GENE_ASSOCIATION: (3295.1) GENE_LIST: 3295.1 SUBSYSTEM: Bile Acid Biosynthesis
5-methyltetrahydrofolate transport via anion exchange
GENE_ASSOCIATION: (6573.1) or (6573.2) GENE_LIST: 6573.1 6573.2 SUBSYSTEM: Transport, Extracellular
2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating) (mitochondria)
nucleoside-diphosphate kinase (ATP:dCDP), nuclear
GENE_ASSOCIATION: (4831.1 and 4830.1) or (4830.2 and 4831.1) GENE_LIST: 4830.1 4830.2 4831.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (586.1) GENE_LIST: 586.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (788.1) GENE_LIST: 788.1 SUBSYSTEM: Carnitine shuttle
UDPglucuronate uridine-diphosphohydrolase
SUBSYSTEM: Pentose and Glucuronate Interconversions
3,4-Dihydroxyphenylethyleneglycol transport (diffusion)
GENE_ASSOCIATION: (2194.1) GENE_LIST: 2194.1 SUBSYSTEM: Fatty acid elongation
GENE_ASSOCIATION: (8802.1 and 8803.1) GENE_LIST: 8802.1 8803.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (2539.1) GENE_LIST: 2539.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (51727.1) GENE_LIST: 51727.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (6647.1) GENE_LIST: 6647.1 SUBSYSTEM: ROS Detoxification
GENE_ASSOCIATION: (2744.1) or (27165.2) or (27165.1) GENE_LIST: 27165.1 27165.2 2744.1 SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (1579.1) GENE_LIST: 1579.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (6785.1) GENE_LIST: 6785.1 SUBSYSTEM: Fatty acid elongation
GENE_ASSOCIATION: (34.1) or (35.1) GENE_LIST: 34.1 35.1 SUBSYSTEM: Fatty acid oxidation
GENE_ASSOCIATION: (51302.1) GENE_LIST: 51302.1 SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (26503.1) GENE_LIST: 26503.1 SUBSYSTEM: Transport, Lysosomal
GENE_ASSOCIATION: (6582.1) or (6582.2) GENE_LIST: 6582.1 6582.2 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (23169.1) GENE_LIST: 23169.1 SUBSYSTEM: Transport, Endoplasmic Reticular
UDPGlcA endoplasmic reticulum transport via UMP antiport
sulfate transport via oxalate countertransport (2:1)
GENE_ASSOCIATION: (65010.1) or (65010.3) or (65010.2) GENE_LIST: 65010.1 65010.2 65010.3 SUBSYSTEM: Transport, Extracellular
phosphatidylinositol 4,5-bisphosphate phospholipase C
SUBSYSTEM: Ascorbate and Aldarate Metabolism
L-arabinitol transport via passive diffusion
transport into the mitochondria (carnitine)
GENE_ASSOCIATION: (6342.1) GENE_LIST: 6342.1 SUBSYSTEM: Bile Acid Biosynthesis
nucleoside-diphosphate kinase (ATP:dGDP), nuclear
GENE_ASSOCIATION: (4357.1) GENE_LIST: 4357.1 SUBSYSTEM: Cysteine Metabolism
GENE_ASSOCIATION: (29968.1) or (29968.2) GENE_LIST: 29968.1 29968.2 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
SUBSYSTEM: Transport, Endoplasmic Reticular
GENE_ASSOCIATION: (290.1) GENE_LIST: 290.1 SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (60386.1) GENE_LIST: 60386.1 SUBSYSTEM: Transport, Mitochondrial
methenyltetrahydrifikate cyclohydrolase, mitochondrial
GENE_ASSOCIATION: (25902.1) or (10797.1) GENE_LIST: 10797.1 25902.1 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (10380.1) GENE_LIST: 10380.1 SUBSYSTEM: Nucleotides
1-alkyl 2-lysoglycerol 3-phosphocholine exchange
GENE_ASSOCIATION: (11254.1) GENE_LIST: 11254.1 SUBSYSTEM: Transport, Extracellular
L-isoleucine transport in via sodium symport
GENE_ASSOCIATION: (6718.1) GENE_LIST: 6718.1 SUBSYSTEM: Bile Acid Biosynthesis
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
GENE_ASSOCIATION: (1854.1) GENE_LIST: 1854.1 SUBSYSTEM: Nucleotides
7-glutamyl-DHF transport,m mitochondrial
GENE_ASSOCIATION: (10840.1) GENE_LIST: 10840.1 SUBSYSTEM: Fatty Acid Metabolism
Valine reversible mitochondrial transport
phosphatidylinositol 4,5-bisphosphate 3-kinase
GENE_ASSOCIATION: (11212.1) GENE_LIST: 11212.1 SUBSYSTEM: Alanine and Aspartate Metabolism
Nicotinamide adenine dinucleotide exchange
GENE_ASSOCIATION: (222.1) or (220.1) or (221.1) or (218.1) GENE_LIST: 218.1 220.1 221.1 222.1 SUBSYSTEM: Tyrosine metabolism
4-Hydroxyphenylacetaldehyde:NADP+ oxidoreductase
bile acid Coenzyme A: amino acid N-acyltransferase
GENE_ASSOCIATION: (570.1) GENE_LIST: 570.1 SUBSYSTEM: Bile Acid Biosynthesis
Retinol transport via faciliated diffusion
GENE_ASSOCIATION: (84693.1) GENE_LIST: 84693.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (29920.1) or (65263.1) GENE_LIST: 29920.1 65263.1 SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (212.1) or (23464.1) or (211.2) or (211.1) GENE_LIST: 211.1 211.2 212.1 23464.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (2356.1) GENE_LIST: 2356.1 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (6723.1) GENE_LIST: 6723.1 SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (6549.1) or (6548.1) or (6550.1) GENE_LIST: 6548.1 6549.1 6550.1 SUBSYSTEM: Transport, Extracellular
1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
GENE_ASSOCIATION: (8659.1) or (8659.2) GENE_LIST: 8659.1 8659.2 SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (10390.1) GENE_LIST: 10390.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (35.1) or (34.1) GENE_LIST: 34.1 35.1 SUBSYSTEM: Fatty acid oxidation
GENE_ASSOCIATION: (3081.1) GENE_LIST: 3081.1 SUBSYSTEM: Tyrosine metabolism
Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
glycine-cleavage system (lipoamide) irreversible, mitochondrial
GENE_ASSOCIATION: (275.1) and (1738.1) and (2731.1) and (2653.1) GENE_LIST: 1738.1 2653.1 2731.1 275.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
betaine-homocysteine S-methyltransferase
GENE_ASSOCIATION: (23743.1) or (635.1) GENE_LIST: 23743.1 635.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (1582.1) GENE_LIST: 1582.1 SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (64078.1) GENE_LIST: 64078.1 SUBSYSTEM: Transport, Extracellular
cytidine transport (1:2 Na/cytd cotransport)
GENE_ASSOCIATION: (2710.2) or (2712.1) or (2710.1) or (2713.1) GENE_LIST: 2710.1 2710.2 2712.1 2713.1 SUBSYSTEM: Glycerophospholipid Metabolism
hydroxylated estrogen derivative transport
GENE_ASSOCIATION: (645.1) or (644.1) GENE_LIST: 644.1 645.1 SUBSYSTEM: Heme Degradation
ribonucleoside-diphosphate reductase (CDP)
GENE_ASSOCIATION: (6240.1 and 6241.1) GENE_LIST: 6240.1 6241.1 SUBSYSTEM: Nucleotides
7-alpha,24(S)-Dihydroxycholesterol exchange
GENE_ASSOCIATION: (1890.1) GENE_LIST: 1890.1 SUBSYSTEM: Pyrimidine Catabolism
nucleoside-diphosphate kinase (ATP:dADP)
GENE_ASSOCIATION: (5723.1) or (8781.1) GENE_LIST: 5723.1 8781.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (10998.1) GENE_LIST: 10998.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (8714.1) or (8714.3) or (8714.2) GENE_LIST: 8714.1 8714.2 8714.3 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (3291.1) GENE_LIST: 3291.1 SUBSYSTEM: Steroid Metabolism
11-beta-hydroxysteroid dehydrogenase type 2
SUBSYSTEM: Urea cycle/amino group metabolism
S-Adenosyl-L-methionine intracellular diffusion
GENE_ASSOCIATION: (3177.1) GENE_LIST: 3177.1 SUBSYSTEM: Transport, Extracellular
thymine reversible transport via facilated diffusion
GENE_ASSOCIATION: (5832.1) GENE_LIST: 5832.1 SUBSYSTEM: Urea cycle/amino group metabolism
glutamate-5-semialdehyde dehydrogenase (m)
GENE_ASSOCIATION: (1593.1) GENE_LIST: 1593.1 SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (1468.1) GENE_LIST: 1468.1 SUBSYSTEM: Transport, Mitochondrial
Fumarate:sulfite antiport, mitochondrial
3-amino-isobutyrate transport, mitochondrial
GENE_ASSOCIATION: (2878.1) or (257202.1) GENE_LIST: 257202.1 2878.1 SUBSYSTEM: Glutathione Metabolism
glycine-cleavage complex (lipoylprotein), mitochondrial
GENE_ASSOCIATION: (1559.1) or (1557.1) GENE_LIST: 1557.1 1559.1 SUBSYSTEM: Limonene and pinene degradation
GENE_ASSOCIATION: (1040.1) GENE_LIST: 1040.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (222.1) or (218.1) or (221.1) or (220.1) GENE_LIST: 218.1 220.1 221.1 222.1 SUBSYSTEM: Phenylalanine metabolism
aldehyde dehydrogenase (phenylacetaldehyde, NAD)
GENE_ASSOCIATION: (6569.1) or (10568.1) GENE_LIST: 10568.1 6569.1 SUBSYSTEM: Transport, Extracellular
phosphate transport in/out via three Na+ symporter
sphingosylphosphorylcholine (homo sapiens)
GENE_ASSOCIATION: (8884.1) GENE_LIST: 8884.1 SUBSYSTEM: Transport, Extracellular
glycerol-3-phosphate dehydrogenase (NAD)
GENE_ASSOCIATION: (2819.1) GENE_LIST: 2819.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (6652.1) GENE_LIST: 6652.1 SUBSYSTEM: Fructose and Mannose Metabolism
D-sorbitol dehydrogenase (D-fructose producing)
2-keto-3-deoxy-D-glycero-D-galactononic acid 9-phosphate
Proline transport (sodium symport) (2:1)
GENE_ASSOCIATION: (6534.1) GENE_LIST: 6534.1 SUBSYSTEM: Transport, Extracellular
keratan sulfate I, degradation product 1
N-acetyl-L-aspartate transport (mitochondria to cytosol)
GENE_ASSOCIATION: (790.1) GENE_LIST: 790.1 SUBSYSTEM: Pyrimidine Biosynthesis
aspartate carbamoyltransferase (reversible)
Gamma-glutamyl hydrolase (10FTHF5GLU), lysosomal
GENE_ASSOCIATION: (8836.1) GENE_LIST: 8836.1 SUBSYSTEM: Folate Metabolism
2-keto-3-deoxy-D-glycero-D-galactononic acid
estrone 3-sulfate transport via bicarbonate countertransport
glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]}) exchange
GENE_ASSOCIATION: (200010.1) GENE_LIST: 200010.1 SUBSYSTEM: Transport, Extracellular
D-mannose transport via sodium cotransport
methylenetetrahydrofolate dehydrogenase (NADP)
GENE_ASSOCIATION: (4522.1) GENE_LIST: 4522.1 SUBSYSTEM: Folate Metabolism
gulonolactone endoplasmic reticular transport
GENE_ASSOCIATION: (114134.1) GENE_LIST: 114134.1 SUBSYSTEM: Transport, Extracellular
inositol transport in via proton symport
GENE_ASSOCIATION: (5625.1) GENE_LIST: 5625.1 SUBSYSTEM: Arginine and Proline Metabolism
prostaglandin transport via bicarbonate countertransport
GENE_ASSOCIATION: (6578.1) GENE_LIST: 6578.1 SUBSYSTEM: Transport, Extracellular
guanosine transport in via sodium (1:2) symport
Hydroxymethylglutaryl-CoA reversible peroxisomal transport
GENE_ASSOCIATION: (1892.1) or (3030.1) and (3032.1) GENE_LIST: 1892.1 3030.1 3032.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
2-Methylprop-2-enoyl-CoA (2-Methylbut-2-enoyl-CoA), mitochondrial
xylitol dehydrogenase (D-xyulose-forming)
GENE_ASSOCIATION: (35.1) or (35.1) or (34.1) or (34.1) GENE_LIST: 34.1 35.1 SUBSYSTEM: Fatty acid oxidation
phosphatidylinositol-4,5-bisphosphate 5-phosphatase
ribose transport in via proton symporter
alcohol dehydrogenase (ethanol, NADP), forward reaction
GENE_ASSOCIATION: (10327.1) or (10327.2) GENE_LIST: 10327.1 10327.2 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (10858.1) GENE_LIST: 10858.1 SUBSYSTEM: Bile Acid Biosynthesis
cytochrome P450, family 46, subfamily A, polypeptide 1
lipid, flip-flop intracellular transport
carboxylic acid dissociation, mitochondrial
SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
L-2-amino-3-oxobutanoate decarboxylation, mitochondrial (spontaneous)
Phosphatidylserine synthase homo sapiens
GENE_ASSOCIATION: (81490.1) GENE_LIST: 81490.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (1376.1) GENE_LIST: 1376.1 SUBSYSTEM: Carnitine shuttle
Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) (cytosol)
GENE_ASSOCIATION: (4128.1) or (4129.1) GENE_LIST: 4128.1 4129.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (5152.1) GENE_LIST: 5152.1 SUBSYSTEM: Nucleotides
3',5'-cyclic-nucleotide phosphodiesterase, Nucleus
Diacylglycerol phosphate kinase (homo sapiens)
GENE_ASSOCIATION: (8525.1) or (9162.1) GENE_LIST: 8525.1 9162.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (788.1) GENE_LIST: 788.1 SUBSYSTEM: Transport, Mitochondrial
L-carnitine transport out of mitochondria via diffusion
Tyrosine:dopa oxidase (dopaquinone producing 2)
GENE_ASSOCIATION: (7299.1) GENE_LIST: 7299.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (83884.1) or (10166.1) GENE_LIST: 10166.1 83884.1 SUBSYSTEM: Transport, Mitochondrial
citrulline mitochondrial transport via proton antiport
GENE_ASSOCIATION: (8802.1 and 8801.1) GENE_LIST: 8801.1 8802.1 SUBSYSTEM: C5-Branched dibasic acid metabolism
Itaconate--CoA ligase (GDP-forming), mitochondrial
nucleoside-diphosphate kinase (ATP:dGDP)
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
GENE_ASSOCIATION: (2180.1) GENE_LIST: 2180.1 SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (6566.1) or (9123.1) or (9194.1) GENE_LIST: 6566.1 9123.1 9194.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (10998.1) or (11001.1) GENE_LIST: 10998.1 11001.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2531.1) GENE_LIST: 2531.1 SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (1644.1) GENE_LIST: 1644.1 SUBSYSTEM: Tryptophan metabolism
nucleoside-diphosphate kinase (ATP:UDP), nuclear
GENE_ASSOCIATION: (3422.1) or (91734.1) GENE_LIST: 3422.1 91734.1 SUBSYSTEM: Cholesterol Metabolism
betaine-aldehyde dehydrogenase, mitochondrial
GENE_ASSOCIATION: (56301.1) and (6520.1) GENE_LIST: 56301.1 6520.1 SUBSYSTEM: Transport, Extracellular
purine-nucleoside phosphorylase (Inosine)
GENE_ASSOCIATION: (4860.1) GENE_LIST: 4860.1 SUBSYSTEM: Purine Catabolism
serine-pyruvate aminotransferase (irreversible), peroxisomal
GENE_ASSOCIATION: (189.1) GENE_LIST: 189.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
arachidonic acid transport into the mitochondria
GENE_ASSOCIATION: (1559.1) GENE_LIST: 1559.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (6783.1) or (6822.1) GENE_LIST: 6783.1 6822.1 SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (6526.1) GENE_LIST: 6526.1 SUBSYSTEM: Transport, Extracellular
(R)-3-Hydroxybutanoate transport via H+ symport
hydroxyphenylacetate transport via diffusion
Gamma-glutamyl hydrolase (5DHF), lysosomal
carnitine O-aceyltransferase, mitochondrial
GENE_ASSOCIATION: (1384.1) GENE_LIST: 1384.1 SUBSYSTEM: Fatty Acid Metabolism
omega hydroxy hexadecanoate (n-C16:0) exchange
3-mercaptolactate-cysteine disulfide transport, extracellular
GENE_ASSOCIATION: (4598.1) GENE_LIST: 4598.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (57379.1) GENE_LIST: 57379.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (2944.1) or (2944.2) GENE_LIST: 2944.1 2944.2 SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (4548.1) GENE_LIST: 4548.1 SUBSYSTEM: Methionine Metabolism
GENE_ASSOCIATION: (6523.1) GENE_LIST: 6523.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (51478.1) GENE_LIST: 51478.1 SUBSYSTEM: Steroid Metabolism
Platelet-activating factor acetylhydrolase
GENE_ASSOCIATION: (7941.1) GENE_LIST: 7941.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (10991.1) GENE_LIST: 10991.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (22978.1) GENE_LIST: 22978.1 SUBSYSTEM: Nucleotides
nucleoside-diphosphate kinase (ATP:dUDP), nuclear
GENE_ASSOCIATION: (10396.1) or (57194.1) GENE_LIST: 10396.1 57194.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2739.1) GENE_LIST: 2739.1 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (229.1) GENE_LIST: 229.1 SUBSYSTEM: Galactose metabolism
D-Tagatose 1-phosphate D-glyceraldehyde-3-phosphate-lyase
GENE_ASSOCIATION: (8833.1) GENE_LIST: 8833.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (259230.1) GENE_LIST: 259230.1 SUBSYSTEM: Sphingolipid Metabolism
phosphatidylinositol nuclear transport (diffusion)
protoporphyrinogen IX mitochondrial transport
C-3 sterol dehydrogenase (4-methylzymosterol)
GENE_ASSOCIATION: (50814.1) GENE_LIST: 50814.1 SUBSYSTEM: Cholesterol Metabolism
Diphosphate transporter, endoplasmic reticulum
GENE_ASSOCIATION: (9058.1) GENE_LIST: 9058.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2805.1) GENE_LIST: 2805.1 SUBSYSTEM: Alanine and Aspartate Metabolism
fatty acyl-CoA desaturase (n-C20:4CoA -> n-C20:5CoA)
GENE_ASSOCIATION: (3992.1) GENE_LIST: 3992.1 SUBSYSTEM: Fatty acid elongation
GENE_ASSOCIATION: (23600.1) or (23600.2) GENE_LIST: 23600.1 23600.2 SUBSYSTEM: Bile Acid Biosynthesis
alpha-methylacyl-CoA racemase (reductase)
GENE_ASSOCIATION: (8942.1) GENE_LIST: 8942.1 SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (2519.1) GENE_LIST: 2519.1 SUBSYSTEM: N-Glycan Degradation
superoxide anion transport via diffusion (extracellular)
thiosulfate transport via sodium symport
GENE_ASSOCIATION: (6561.1) GENE_LIST: 6561.1 SUBSYSTEM: Transport, Extracellular
pyruvate reversible transport via proton symport
GENE_ASSOCIATION: (6535.1) or (6537.1) GENE_LIST: 6535.1 6537.1 SUBSYSTEM: Transport, Extracellular
Creatine transport (sodium symport) (2:1)
GENE_ASSOCIATION: (231.1) GENE_LIST: 231.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (4833.1) GENE_LIST: 4833.1 SUBSYSTEM: Nucleotides
nucleoside-diphosphate kinase (ATP:dUDP), mitochondrial
hyaluronan transport, extracellular to lysosome
GENE_ASSOCIATION: (226.2) or (226.1) or (226.3) or (229.1) or (230.1) GENE_LIST: 226.1 226.2 226.3 229.1 230.1 SUBSYSTEM: Fructose and Mannose Metabolism
D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase
GENE_ASSOCIATION: (7086.1) or (84076.1) or (8277.1) GENE_LIST: 7086.1 8277.1 84076.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (3990.1) GENE_LIST: 3990.1 SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (6515.1) or (6513.1) or (6517.1) GENE_LIST: 6513.1 6515.1 6517.1 SUBSYSTEM: Transport, Extracellular
metanephrine secretion via secretory vesicle (ATP driven)
ribonucleoside-diphosphate reductase (GDP)
GENE_ASSOCIATION: (5321.1) or (1178.1) or (29124.1) GENE_LIST: 1178.1 29124.1 5321.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (9791.1) GENE_LIST: 9791.1 SUBSYSTEM: Glycerophospholipid Metabolism
T4 transport via bicarbonate countertransport
hydrogen peroxide transport via diffusion
alpha-amylase, extracellular (glygn2 -> glygn4)
3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase
7-glutamyl-THF transport,m mitochondrial
GENE_ASSOCIATION: (8897.1) or (8897.3) or (8897.2) GENE_LIST: 8897.1 8897.2 8897.3 SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol-3,5-bisphosphate 3-phosphatase
L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
GENE_ASSOCIATION: (7166.1) or (121278.1) GENE_LIST: 121278.1 7166.1 SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (6560.1) or (10723.1) or (9990.1) GENE_LIST: 10723.1 6560.1 9990.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (6580.1) or (6582.2) or (6582.1) GENE_LIST: 6580.1 6582.1 6582.2 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (10087.1) GENE_LIST: 10087.1 SUBSYSTEM: Transport, Endoplasmic Reticular
GENE_ASSOCIATION: (6554.1) GENE_LIST: 6554.1 SUBSYSTEM: Transport, Extracellular
estrone-3-sulfate transport via sodium cotransport
nicotinamide-nucleotide adenylyltransferase
dihydrofolate reversible lysosomal transport
GENE_ASSOCIATION: (55163.1) GENE_LIST: 55163.1 SUBSYSTEM: Vitamin B6 Metabolism
purine-nucleoside phosphorylase (Deoxyinosine)
GENE_ASSOCIATION: (316.1) GENE_LIST: 316.1 SUBSYSTEM: Vitamin B6 Metabolism
GENE_ASSOCIATION: (11001.1) GENE_LIST: 11001.1 SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (4907.1) GENE_LIST: 4907.1 SUBSYSTEM: Nucleotides
1D-myo-Inositol 1,3,4,5-tetrakisphosphate
GENE_ASSOCIATION: (1807.1) or (1809.1) or (1808.1) GENE_LIST: 1807.1 1808.1 1809.1 SUBSYSTEM: Pyrimidine Catabolism
L-tryptophan transport in via sodium symport
UDP-glucuronosyltransferase 1-10 precursor, microsomal
GENE_ASSOCIATION: (54575.1) or (54576.1) GENE_LIST: 54575.1 54576.1 SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (30833.1) GENE_LIST: 30833.1 SUBSYSTEM: Pyrimidine Catabolism
GENE_ASSOCIATION: (1841.1) GENE_LIST: 1841.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (11343.1) or (11343.2) GENE_LIST: 11343.1 11343.2 SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (210.1) or (210.2) GENE_LIST: 210.1 210.2 SUBSYSTEM: Heme Biosynthesis
GENE_ASSOCIATION: (51268.1) GENE_LIST: 51268.1 SUBSYSTEM: Lysine Metabolism
glucose-6-phosphate phosphatase, edoplasmic reticular
GENE_ASSOCIATION: (57818.1) or (2538.1) or (92579.1) GENE_LIST: 2538.1 57818.1 92579.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
7-glutamyl-10FTHF transport, mitochondrial
GENE_ASSOCIATION: (2936.1) GENE_LIST: 2936.1 SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (1757.1) GENE_LIST: 1757.1 SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (3938.1) GENE_LIST: 3938.1 SUBSYSTEM: Galactose metabolism
Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)
D-Lactaldehyde:NAD+ oxidoreductase (glutathione-formylating)
GENE_ASSOCIATION: (128.1) GENE_LIST: 128.1 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (5338.1) GENE_LIST: 5338.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (1562.1) GENE_LIST: 1562.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (64080.1) GENE_LIST: 64080.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (51380.1) or (2571.1) or (2572.1) or (2571.2) GENE_LIST: 2571.1 2571.2 2572.1 51380.1 SUBSYSTEM: Taurine and hypotaurine metabolism
GENE_ASSOCIATION: (4837.1) GENE_LIST: 4837.1 SUBSYSTEM: NAD Metabolism
aldehyde dehydrogenase (acetaldehyde, NADP)
GENE_ASSOCIATION: (9420.1) GENE_LIST: 9420.1 SUBSYSTEM: Bile Acid Biosynthesis
acetoacetate intracellular transport unknown mechanism
Iodide:hydrogen-peroxide oxidoreductase 4
phosphatidylinositol-3-phosphate 3-phosphatase
GENE_ASSOCIATION: (8897.2) or (8897.3) or (8897.1) GENE_LIST: 8897.1 8897.2 8897.3 SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (4023.1) GENE_LIST: 4023.1 SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (2181.1) or (2181.2) GENE_LIST: 2181.1 2181.2 SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (2990.1) GENE_LIST: 2990.1 SUBSYSTEM: Hyaluronan Metabolism
GENE_ASSOCIATION: (1577.1) GENE_LIST: 1577.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (54981.1) GENE_LIST: 54981.1 SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (1373.1) or (1373.2) GENE_LIST: 1373.1 1373.2 SUBSYSTEM: Glutamate metabolism
carbamoyl-phosphate synthase (ammonia) (mitochondria
L-lysine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (9060.1) or (9061.1) GENE_LIST: 9060.1 9061.1 SUBSYSTEM: Nucleotides
Glutathione dehydrogenase (dehydroascorbate reductase)
GENE_ASSOCIATION: (1120.2) or (1119.1) or (1120.1) or (1119.2) GENE_LIST: 1119.1 1119.2 1120.1 1120.2 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (6541.1) or (84889.1) or (6542.1) GENE_LIST: 6541.1 6542.1 84889.1 SUBSYSTEM: Transport, Extracellular
ornithine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (412.1) GENE_LIST: 412.1 SUBSYSTEM: Steroid Metabolism
cytochrome c oxidase, mitochondrial Complex IV
GENE_ASSOCIATION: (134526.1) GENE_LIST: 134526.1 SUBSYSTEM: Pyruvate Metabolism
Sulfate derivative of norepinephrine exchange
docosa-4,7,10,13,16-pentaenoic acid (n-6)
10-Formyltetrahydrofolate mitochondrial transport via diffusion
GENE_ASSOCIATION: (6528.1) GENE_LIST: 6528.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (6582.1) or (6584.1) or (6582.2) GENE_LIST: 6582.1 6582.2 6584.1 SUBSYSTEM: Transport, Extracellular
ornithine mitochondrial transport via proton antiport
GENE_ASSOCIATION: (124583.1) GENE_LIST: 124583.1 SUBSYSTEM: Nucleotides
nucleoside-diphosphatase (UTP), extracellular
GENE_ASSOCIATION: (11254.1) or (54407.1) GENE_LIST: 11254.1 54407.1 SUBSYSTEM: Transport, Extracellular
L-histidine transport in via sodium symport
glucose-6-phosphate dehydrogenase, endoplasmic reticulum
GENE_ASSOCIATION: (9563.1) GENE_LIST: 9563.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (5105.1) GENE_LIST: 5105.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
Thiamine monophosphate transport in via anion antiport
folylpolyglutamate synthetase (DHF), mitochondrial
GENE_ASSOCIATION: (26266.1) GENE_LIST: 26266.1 SUBSYSTEM: Transport, Extracellular
docosa-4,7,10,13,16-pentaenoyl coenzyme A
Triiodothyronine sulfate transport (diffusion)
carbamoyl-phosphate synthase (glutamine-hydrolysing)
heptadecanoate transport into the mitochondria
Thiocyanate transport via diffusion (cytosol to extracellular)
GENE_ASSOCIATION: (2592.1) or (2592.3) or (2592.2) GENE_LIST: 2592.1 2592.2 2592.3 SUBSYSTEM: Galactose metabolism
UDPglucose--hexose-1-phosphate uridylyltransferase
GENE_ASSOCIATION: (26002.1) or (1621.1) GENE_LIST: 1621.1 26002.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (43.1) or (43.2) GENE_LIST: 43.1 43.2 SUBSYSTEM: Glycerophospholipid Metabolism
L-3-aminoisobutyrate transaminase, mitochondrial
GENE_ASSOCIATION: (18.1) or (18.2) GENE_LIST: 18.1 18.2 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (5836.1) or (5837.1) or (5834.1) GENE_LIST: 5834.1 5836.1 5837.1 SUBSYSTEM: Starch and Sucrose Metabolism
3-Methylimidazole acetaldehyde:NAD+ oxidoreductase
phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})
C-4 sterol methyl oxidase (4,4-dimethylzymosterol)
GENE_ASSOCIATION: (6307.1) GENE_LIST: 6307.1 SUBSYSTEM: Cholesterol Metabolism
Malate:thiosulfate antiport, mitochondrial
GENE_ASSOCIATION: (22978.1) GENE_LIST: 22978.1 SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (10841.1) or (10841.2) GENE_LIST: 10841.1 10841.2 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (27010.1) GENE_LIST: 27010.1 SUBSYSTEM: Thiamine Metabolism
GENE_ASSOCIATION: (55902.1) or (65985.1) or (55902.2) GENE_LIST: 55902.1 55902.2 65985.1 SUBSYSTEM: Propanoate Metabolism
4-methyl-2-oxopentanoate mitochondrial transport via proton symport
GENE_ASSOCIATION: (6510.1) GENE_LIST: 6510.1 SUBSYSTEM: Transport, Extracellular
L-threonine/L-asparagine Na-dependent exchange (Thr-L in)
GENE_ASSOCIATION: (10396.1) or (57194.1) GENE_LIST: 10396.1 57194.1 SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: (7054.1) or (7054.3) or (7054.2) GENE_LIST: 7054.1 7054.2 7054.3 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (1109.1) GENE_LIST: 1109.1 SUBSYSTEM: Bile Acid Biosynthesis
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
GENE_ASSOCIATION: (6470.1) or (6470.2) GENE_LIST: 6470.1 6470.2 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
glycine hydroxymethyltransferase, reversible
V-type ATPase, H+ transporting, lysosomal
GENE_ASSOCIATION: (5831.1) or (5831.2) GENE_LIST: 5831.1 5831.2 SUBSYSTEM: Arginine and Proline Metabolism
GENE_ASSOCIATION: (8566.1) GENE_LIST: 8566.1 SUBSYSTEM: Vitamin B6 Metabolism
GENE_ASSOCIATION: (25796.1) GENE_LIST: 25796.1 SUBSYSTEM: Pentose Phosphate Pathway
2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial
hydrogen peroxide mitochondrial transport
3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase
GENE_ASSOCIATION: (221.1) or (222.1) GENE_LIST: 221.1 222.1 SUBSYSTEM: Tyrosine metabolism
folylpolyglutamate synthetase, mitochondrial
GENE_ASSOCIATION: (10558.1 and 9517.1) GENE_LIST: 10558.1 9517.1 SUBSYSTEM: Sphingolipid Metabolism
3,4-Dihydroxyphenylacetaldehyde:NADP+ oxidoreductase
GENE_ASSOCIATION: (222.1) or (221.1) or (218.1) GENE_LIST: 218.1 221.1 222.1 SUBSYSTEM: Tyrosine metabolism
3-methyl-2-oxobutanoate mitochondrial transport via proton symport
fatty acyl-CoA desaturase (n-C18:1CoA -> n-C18:2CoA)
GENE_ASSOCIATION: (9415.1) GENE_LIST: 9415.1 SUBSYSTEM: Fatty acid elongation
succinate-semialdehyde dehydrogenase (NAD) reversible (mitochondrial)
GENE_ASSOCIATION: (7915.1) or (7915.2) GENE_LIST: 7915.1 7915.2 SUBSYSTEM: Glutamate metabolism
SUBSYSTEM: Arginine and Proline Metabolism
5-methylthioribose-1-phosphate isomerase
3-sulfinopyruvate hydrolase (spotaneous reaction), mitochondrial
retinoyl glucuronide efflux (13-cis) from ER
(R)-3-Hydroxybutanoate mitochondrial transport via H+ symport
GENE_ASSOCIATION: (80270.1) GENE_LIST: 80270.1 SUBSYSTEM: Bile Acid Biosynthesis
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
glycine-cleavage complex (lipoamide), mitochondrial
acetate reversible transport via proton symport
SUBSYSTEM: Taurine and hypotaurine metabolism
GENE_ASSOCIATION: (80347.1) GENE_LIST: 80347.1 SUBSYSTEM: CoA Biosynthesis
alcohol dehydrogenase (L-1,2-propanediol)
Thiocyanate transport via diffusion (mitochondrial)
beta-Aminopropion aldehyde:NAD+ oxidoreductase
GENE_ASSOCIATION: (2203.1) or (8789.1) GENE_LIST: 2203.1 8789.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (55089.1) GENE_LIST: 55089.1 SUBSYSTEM: Transport, Extracellular
L-histidine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (7167.1) or (286016.1) GENE_LIST: 286016.1 7167.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (7108.1) GENE_LIST: 7108.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (93034.1) or (30833.1) or (93034.2) GENE_LIST: 30833.1 93034.1 93034.2 SUBSYSTEM: Pyrimidine Catabolism
3,4-Dihydroxyphenylethyleneglycol exchange
GENE_ASSOCIATION: (3795.1) or (3795.2) GENE_LIST: 3795.1 3795.2 SUBSYSTEM: Galactose metabolism
Linoleic acid (n-C18:2) transport in via diffusion
5-Methylthio-5-deoxy-D-ribose 1-phosphate
GENE_ASSOCIATION: (2937.1) GENE_LIST: 2937.1 SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (6576.1) GENE_LIST: 6576.1 SUBSYSTEM: Transport, Mitochondrial
5-Methylthio-5-deoxy-D-ribulose 1-phosphate
GENE_ASSOCIATION: (5053.1) GENE_LIST: 5053.1 SUBSYSTEM: Tyr, Phe, Trp Biosynthesis
L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
Methylglyoxal transport (cytosol to extracellular)
GENE_ASSOCIATION: (10965.1) GENE_LIST: 10965.1 SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (1717.1) GENE_LIST: 1717.1 SUBSYSTEM: Cholesterol Metabolism
methylmalonate-semialdehyde dehydrogenase
GENE_ASSOCIATION: (4329.1) GENE_LIST: 4329.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (2639.1) or (2639.2) GENE_LIST: 2639.1 2639.2 SUBSYSTEM: Tryptophan metabolism
glutaryl-CoA dehydrogenase (mitochondria)
b-ketoacyl synthetase (palmitate, n-C16:0)
aspartate-glutamate mitochondrial shuttle
GENE_ASSOCIATION: (8604.1) or (10165.1) GENE_LIST: 10165.1 8604.1 SUBSYSTEM: Transport, Mitochondrial
glycerol-3-phosphate dehydrogenase (FAD), mitochondrial
GENE_ASSOCIATION: (2820.1) GENE_LIST: 2820.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (7371.1) or (83549.1) GENE_LIST: 7371.1 83549.1 SUBSYSTEM: Pyrimidine Biosynthesis
GENE_ASSOCIATION: (1595.1) GENE_LIST: 1595.1 SUBSYSTEM: Cholesterol Metabolism
cytochrome P450 lanosterol 14-alpha-demethylase
sodium transport via diffusion (perioxisome)
deoxyguanylate kinase (dGMP:dATP) (mitochondrial)
5-beta-cytochrome P450, family 27, subfamily A, polypeptide 1
GENE_ASSOCIATION: (5210.1) or (5207.1) or (5209.1) or (5208.1) GENE_LIST: 5207.1 5208.1 5209.1 5210.1 SUBSYSTEM: Fructose and Mannose Metabolism
GENE_ASSOCIATION: (2729.1) and (2730.1) GENE_LIST: 2729.1 2730.1 SUBSYSTEM: Glutathione Metabolism
3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase
GENE_ASSOCIATION: (2030.1) GENE_LIST: 2030.1 SUBSYSTEM: Transport, Mitochondrial
adenosine facilated transport in mitochondria
GENE_ASSOCIATION: (23657.1 and 6520.1) GENE_LIST: 23657.1 6520.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (8639.1) or (26.1) or (314.2) or (314.1) GENE_LIST: 26.1 314.1 314.2 8639.1 SUBSYSTEM: Tyrosine metabolism
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (mitochondria)
GENE_ASSOCIATION: (1103.4) or (1103.2) or (1103.3) or (1103.1) GENE_LIST: 1103.1 1103.2 1103.3 1103.4 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (847.1) GENE_LIST: 847.1 SUBSYSTEM: ROS Detoxification
GENE_ASSOCIATION: (39.1) GENE_LIST: 39.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (6648.1) GENE_LIST: 6648.1 SUBSYSTEM: ROS Detoxification
GENE_ASSOCIATION: (3155.1) GENE_LIST: 3155.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (2806.1) GENE_LIST: 2806.1 SUBSYSTEM: Cysteine Metabolism
3-sulfino-alanine transaminase (irreversible), mitochondrial
GENE_ASSOCIATION: (6519.1 and 11136.1) GENE_LIST: 11136.1 6519.1 SUBSYSTEM: Transport, Extracellular
L-cystine/glycine exchanger (cystine in)
cysteinesulfinate-aspartate mitochondrial shuttle
GENE_ASSOCIATION: (10165.1) or (8604.1) GENE_LIST: 10165.1 8604.1 SUBSYSTEM: Transport, Mitochondrial
Creatine transport to/from mitochondria via diffusion
GENE_ASSOCIATION: (1503.1) GENE_LIST: 1503.1 SUBSYSTEM: Nucleotides
UDPglucuronate uridine-monophosphohydrolase
glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})
glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})
GENE_ASSOCIATION: (1159.1) or (1160.1) GENE_LIST: 1159.1 1160.1 SUBSYSTEM: Urea cycle/amino group metabolism
S-Adenosyl-L-methionine reversible transport, mitochondrial
glycogen, structure 3 (glycogenin-7[1,4-Glc])
4-aminobutanoate mitochondrial transport via diffusion
ubiquinol-6 cytochrome c reductase, Complex III
GENE_ASSOCIATION: (53905.1) or (50506.1) or (53905.2) GENE_LIST: 50506.1 53905.1 53905.2 SUBSYSTEM: Tyrosine metabolism
Hydrogen peroxide synthesis (NADPH dependent)
GENE_ASSOCIATION: (1553.1) or (1548.1) GENE_LIST: 1548.1 1553.1 SUBSYSTEM: CYP Metabolism
docosa-4,7,10,13,16-pentaenoic acid (n-6) exchange
GENE_ASSOCIATION: (2987.1) GENE_LIST: 2987.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (1633.1) GENE_LIST: 1633.1 SUBSYSTEM: Nucleotides
nucleoside-diphosphate kinase (ATP:dIDP)
GENE_ASSOCIATION: (7360.1) or (7359.1) or (7360.2) GENE_LIST: 7359.1 7360.1 7360.2 SUBSYSTEM: Galactose metabolism
UTP-glucose-1-phosphate uridylyltransferase
GENE_ASSOCIATION: (3614.1) or (3615.1) or (3614.2) GENE_LIST: 3614.1 3614.2 3615.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (9380.1) GENE_LIST: 9380.1 SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
GENE_ASSOCIATION: (3030.1) and (3032.1) or (38.1) GENE_LIST: 3030.1 3032.1 38.1 SUBSYSTEM: Tryptophan metabolism
acetyl-CoA C-acetyltransferase, mitochondrial
glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]}) exchange
GENE_ASSOCIATION: (23761.1) GENE_LIST: 23761.1 SUBSYSTEM: Glycerophospholipid Metabolism
phosphatidylinositol-5-phosphate 3-kinase
nucleoside-diphosphate kinase (ATP:dGDP), mitochondrial
5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
Acetylcholin transport, nuclear trhough pores
GENE_ASSOCIATION: (549.1) GENE_LIST: 549.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
methylglutaconyl-CoA hydratase (reversible), mitochondrial
GENE_ASSOCIATION: (11112.1) GENE_LIST: 11112.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
3-hydroxyisobutyrate dehydrogenase, mitochondrial
GENE_ASSOCIATION: (4191.1) GENE_LIST: 4191.1 SUBSYSTEM: Citric Acid Cycle
taurine transport (sodium symport) (2:1)
GENE_ASSOCIATION: (6533.1) GENE_LIST: 6533.1 SUBSYSTEM: Transport, Extracellular
docosa-4,7,10,13,16-pentaenoyl carnitine
tetrahydrofolate transport via anion exchange
L-aminoadipate-semialdehyde dehydrogenase (NADH)
GENE_ASSOCIATION: (5409.1) GENE_LIST: 5409.1 SUBSYSTEM: Tyrosine metabolism
Squalene epoxidase, endoplasmic reticular (NADP)
GENE_ASSOCIATION: (6713.1) GENE_LIST: 6713.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (6579.1) or (10599.1) GENE_LIST: 10599.1 6579.1 SUBSYSTEM: Transport, Extracellular
cholate transport via bicarbonate countertransport
GENE_ASSOCIATION: (5009.1) GENE_LIST: 5009.1 SUBSYSTEM: Urea cycle/amino group metabolism
ornithine carbamoyltransferase, irreversible
GENE_ASSOCIATION: (51181.1) GENE_LIST: 51181.1 SUBSYSTEM: Pentose and Glucuronate Interconversions
inorganic diphosphatase, endoplasmic reticulum
ribonucleoside-diphosphate reductase (ADP)
GENE_ASSOCIATION: (978.1) or (57379.1) GENE_LIST: 57379.1 978.1 SUBSYSTEM: Pyrimidine Catabolism
GENE_ASSOCIATION: (952.1) GENE_LIST: 952.1 SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (8760.1) GENE_LIST: 8760.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (6005.1) or (57127.1) GENE_LIST: 57127.1 6005.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (6307.1) or (50814.1) GENE_LIST: 50814.1 6307.1 SUBSYSTEM: Cholesterol Metabolism
formate-tetrahydrofolate ligase, mitochondrial
GENE_ASSOCIATION: (25902.1) GENE_LIST: 25902.1 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (1558.1) or (1558.2) GENE_LIST: 1558.1 1558.2 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (376497.1) or (376497.2) GENE_LIST: 376497.1 376497.2 SUBSYSTEM: Transport, Extracellular
glycogen, structure 1 (glycogenin-11[1,4-Glc])
GENE_ASSOCIATION: (100.1) GENE_LIST: 100.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (1644.1) GENE_LIST: 1644.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (1431.1) or (1431.2) GENE_LIST: 1431.1 1431.2 SUBSYSTEM: Citric Acid Cycle
FADH2 transporter, endoplasmic reticulum
GENE_ASSOCIATION: (1571.1) GENE_LIST: 1571.1 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (6566.1) GENE_LIST: 6566.1 SUBSYSTEM: Transport, Extracellular
Butyrate transport via proton symport, reversible
GENE_ASSOCIATION: (4363.1) GENE_LIST: 4363.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (5167.1) or (5169.1) or (5168.1) GENE_LIST: 5167.1 5168.1 5169.1 SUBSYSTEM: NAD Metabolism
nicotinate-nucleotide adenylyltransferase
GENE_ASSOCIATION: (3931.1) GENE_LIST: 3931.1 SUBSYSTEM: Fatty Acid Metabolism
2,3-diketo-5-methylthio-1-phosphopentane degradation reaction
GENE_ASSOCIATION: (56848.1) GENE_LIST: 56848.1 SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (1152.1) or (1158.1) and (1152.1) or (1158.1) GENE_LIST: 1152.1 1158.1 SUBSYSTEM: Urea cycle/amino group metabolism
Iodide:hydrogen-peroxide oxidoreductase 2
GENE_ASSOCIATION: (4047.1) GENE_LIST: 4047.1 SUBSYSTEM: Cholesterol Metabolism
sphingosylphosphorylcholine transport (diffusion)
GENE_ASSOCIATION: (4351.1) GENE_LIST: 4351.1 SUBSYSTEM: Fructose and Mannose Metabolism
GENE_ASSOCIATION: (3145.1) GENE_LIST: 3145.1 SUBSYSTEM: Heme Biosynthesis
GENE_ASSOCIATION: (1610.1) GENE_LIST: 1610.1 SUBSYSTEM: D-alanine metabolism
fatty acyl-CoA desaturase (n-C18:2CoA -> n-C18:3CoA)
5-formethyltetrahydrofolate cyclo-ligase
GENE_ASSOCIATION: (10588.1) GENE_LIST: 10588.1 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (6574.1) or (6575.1) GENE_LIST: 6574.1 6575.1 SUBSYSTEM: Transport, Extracellular
phosphate transport in/out via Na+ symporter
GENE_ASSOCIATION: (55349.1) GENE_LIST: 55349.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
choline dehydrogenase (FAD acceptor), mitochondrial
5-Methyltetrahydrofolate transport via receptor binding and protolysis
D-fructose transport via sodium cotransport
GENE_ASSOCIATION: (763.1) or (11238.1) GENE_LIST: 11238.1 763.1 SUBSYSTEM: Miscellaneous
GENE_ASSOCIATION: (5236.1) or (55276.1) GENE_LIST: 5236.1 55276.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (3029.1) or (84264.2) or (84264.1) GENE_LIST: 3029.1 84264.1 84264.2 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (23464.1) GENE_LIST: 23464.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
Gamma-glutamyl hydrolase (5THF), lysosomal
This is the genome-scale metabolic network described in the article: Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism Livnat Jerby, Tomer Shlomi, and Eytan Ruppin; Molecular Systems Biology 6:401, 2010; PmID: 20823844 , DOI: 10.1038/msb.2010.56 Abstract: The computational study of human metabolism has been advanced with the advent of the first generic (non-tissue specific) stoichiometric model of human metabolism. In this study, we present a new algorithm for rapid reconstruction of tissue-specific genome-scale models of human metabolism. The algorithm generates a tissue-specific model from the generic human model by integrating a variety of tissue-specific molecular data sources, including literature-based knowledge, transcriptomic, proteomic, metabolomic and phenotypic data. Applying the algorithm, we constructed the first genome-scale stoichiometric model of hepatic metabolism. The model is verified using standard cross-validation procedures, and through its ability to carry out hepatic metabolic functions. The model's flux predictions correlate with flux measurements across a variety of hormonal and dietary conditions, and improve upon the predictive performance obtained using the original, generic human model (prediction accuracy of 0.67 versus 0.46). Finally, the model better predicts biomarker changes in genetic metabolic disorders than the generic human model (accuracy of 0.67 versus 0.59). The approach presented can be used to construct other human tissue-specific models, and be applied to other organisms. The original SBML version was produced by COBRA_Toolbox and downloaded from the suplementary material of the article. To make this model SBML compliant, the unit for the FLUX_VALUE parameters had to be changed from mmole per gramm dry weight per hour to mmole per hr. To change the model back to its original form, either alter the unit definition of the unit mmol_per_hr accordingly or replace mmol_per_hr by mmol_per_gDW_per_hr in all reactions. This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
GENE_ASSOCIATION: (2805.1) GENE_LIST: 2805.1 SUBSYSTEM: Cysteine Metabolism
L-Cysteate:2-oxoglutarate aminotransferase
GENE_ASSOCIATION: (1119.2) or (55500.1) or (1119.1) or (55224.1) GENE_LIST: 1119.1 1119.2 55224.1 55500.1 SUBSYSTEM: Glycerophospholipid Metabolism
carnitine O-aceyltransferase, peroxisomal
GENE_ASSOCIATION: (1384.2) GENE_LIST: 1384.2 SUBSYSTEM: Carnitine shuttle
GENE_ASSOCIATION: (8574.1) GENE_LIST: 8574.1 SUBSYSTEM: Pyruvate Metabolism
alcohol dehydrogenase, forward rxn (ethanol -> acetaldehyde)
GENE_ASSOCIATION: (3631.2) or (3631.1) or (8821.1) GENE_LIST: 3631.1 3631.2 8821.1 SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (1545.1) GENE_LIST: 1545.1 SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (4594.1) GENE_LIST: 4594.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (875.1) GENE_LIST: 875.1 SUBSYSTEM: Methionine Metabolism
10-Formyltetrahydrofolate lysosomal transport via diffusion
GENE_ASSOCIATION: (6319.1) GENE_LIST: 6319.1 SUBSYSTEM: Fatty acid elongation
stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)
cytidine facilated transport in mitochondria
GENE_ASSOCIATION: (3295.1) GENE_LIST: 3295.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (64802.1) GENE_LIST: 64802.1 SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (6389.1 and 6392.1 and 6391.1 and 6390.1) GENE_LIST: 6389.1 6390.1 6391.1 6392.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (6584.1) GENE_LIST: 6584.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (952.1) GENE_LIST: 952.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (262.1) GENE_LIST: 262.1 SUBSYSTEM: Arginine and Proline Metabolism
phosphatidylethanolamine (homo sapiens) exchange
GENE_ASSOCIATION: (587.1) GENE_LIST: 587.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
superoxide anion transport via diffusion (mitochondria)
GENE_ASSOCIATION: (8659.1) or (8659.2) GENE_LIST: 8659.1 8659.2 SUBSYSTEM: Arginine and Proline Metabolism
L-4-hydroxyglutamate semialdehyde dehydrogenase, mitochondrial
Phosphocreatine transport to/from mitochondria via diffusion
GENE_ASSOCIATION: (8639.1) GENE_LIST: 8639.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)
GENE_ASSOCIATION: (1103.4) or (1103.1) or (1103.3) or (1103.2) GENE_LIST: 1103.1 1103.2 1103.3 1103.4 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (5230.1) or (348477.1) or (5232.1) GENE_LIST: 348477.1 5230.1 5232.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
5,10-methylenetetrahydrofolatereductase (NADPH)
GENE_ASSOCIATION: (4524.1) GENE_LIST: 4524.1 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (7084.1) GENE_LIST: 7084.1 SUBSYSTEM: Nucleotides
deoxyuridine kinase (ATP:Deoxyuridine), mitochondrial
GENE_ASSOCIATION: (7498.1) GENE_LIST: 7498.1 SUBSYSTEM: Purine Catabolism
GENE_ASSOCIATION: (10390.1) or (56994.1) GENE_LIST: 10390.1 56994.1 SUBSYSTEM: Glycerophospholipid Metabolism
(R)-3-Hydroxybutanoate:NAD+ oxidoreductase
GENE_ASSOCIATION: (622.2) or (622.3) or (622.1) GENE_LIST: 622.1 622.2 622.3 SUBSYSTEM: Butanoate Metabolism
7-alpha,27-Dihydroxycholesterol exchange
GENE_ASSOCIATION: (191.1) or (10768.2) or (10768.1) GENE_LIST: 10768.1 10768.2 191.1 SUBSYSTEM: Methionine Metabolism
L-leucine transport in via sodium symport
GENE_ASSOCIATION: (5298.1) or (55361.1) or (5297.1) GENE_LIST: 5297.1 5298.1 55361.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (7084.1) or (7083.1) GENE_LIST: 7083.1 7084.1 SUBSYSTEM: Nucleotides
gulonate dehydrogenase, endoplasmic reticulum
GENE_ASSOCIATION: (5730.1) or (27306.1) GENE_LIST: 27306.1 5730.1 SUBSYSTEM: Eicosanoid Metabolism
Prostaglandin-H2 D-isomerase [Precursor]
guanidinoacetate N-methyltransferase (c)
GENE_ASSOCIATION: (2593.1) or (2593.2) GENE_LIST: 2593.1 2593.2 SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (1557.1) GENE_LIST: 1557.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (23417.1) GENE_LIST: 23417.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
Methylmalonyl-CoA decarboxylase, mitochondrial
Cyanide transport via diffusion (mitochondrial)
GENE_ASSOCIATION: (5091.1) or (5091.2) GENE_LIST: 5091.1 5091.2 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (57678.1) GENE_LIST: 57678.1 SUBSYSTEM: Triacylglycerol Synthesis
cholesterol ester (from FULLR2) exchange
N-acetylglucosamine-6-phosphate deacetylase
GENE_ASSOCIATION: (51005.1) GENE_LIST: 51005.1 SUBSYSTEM: Aminosugar Metabolism
SUBSYSTEM: Fructose and Mannose Metabolism
3-sulfinopyruvate hydrolase (spotaneous reaction)
protoporphyrinogen oxidase, mitochondrial
GENE_ASSOCIATION: (5498.1) GENE_LIST: 5498.1 SUBSYSTEM: Heme Biosynthesis
GENE_ASSOCIATION: (10007.1) or (132789.1) GENE_LIST: 10007.1 132789.1 SUBSYSTEM: Aminosugar Metabolism
Seratonin reversible transport in via sodium symport/potassium antiport (1:2)
GENE_ASSOCIATION: (6532.1) GENE_LIST: 6532.1 SUBSYSTEM: Transport, Extracellular
3-mercaptolactate-cysteine disulfide exchange
CO2 transport (diffusion), mitochondrial
GENE_ASSOCIATION: (2098.1) GENE_LIST: 2098.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (131669.1) GENE_LIST: 131669.1 SUBSYSTEM: Histidine Metabolism
GENE_ASSOCIATION: (3155.1) or (54511.1) GENE_LIST: 3155.1 54511.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (5167.1) GENE_LIST: 5167.1 SUBSYSTEM: Riboflavin Metabolism
GENE_ASSOCIATION: (6557.1) or (6558.1) GENE_LIST: 6557.1 6558.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (8802.1 and 8801.1) GENE_LIST: 8801.1 8802.1 SUBSYSTEM: Citric Acid Cycle
sphingoid base-phosphate phosphatase (sphinganine 1-phosphatase), endoplasmic reticulum
GENE_ASSOCIATION: (81537.1) GENE_LIST: 81537.1 SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (6611.1) GENE_LIST: 6611.1 SUBSYSTEM: Urea cycle/amino group metabolism
superoxide anion transport via diffusion (peroxisome)
GENE_ASSOCIATION: (1719.1) GENE_LIST: 1719.1 SUBSYSTEM: Folate Metabolism
GENE_ASSOCIATION: (23417.1) GENE_LIST: 23417.1 SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (10654.1) GENE_LIST: 10654.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (6566.1) GENE_LIST: 6566.1 SUBSYSTEM: Transport, Mitochondrial
Butyrate mitochondrial transport via proton symport, reversible
GENE_ASSOCIATION: (65985.1) GENE_LIST: 65985.1 SUBSYSTEM: Propanoate Metabolism
GENE_ASSOCIATION: (100.1) GENE_LIST: 100.1 SUBSYSTEM: Purine Catabolism
GENE_ASSOCIATION: (6566.1) or (9194.1) GENE_LIST: 6566.1 9194.1 SUBSYSTEM: D-alanine metabolism
pyruvate peroxisomal transport via proton symport
GENE_ASSOCIATION: (8560.1) or (8560.2) GENE_LIST: 8560.1 8560.2 SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (9615.1) GENE_LIST: 9615.1 SUBSYSTEM: Purine Catabolism
3,4-Dihydroxyphenylethyleneglycol:NAD+ oxidoreductase
Phosphatidylcholine (homo sapiens) exchange
omega hydroxy tetradecanoate (n-C14:0) exchange
carnitine O-acetyltransferase, reverse direction, peroxisomal
GENE_ASSOCIATION: (1384.2) GENE_LIST: 1384.2 SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (5236.1) GENE_LIST: 5236.1 SUBSYSTEM: Pentose Phosphate Pathway
formaldehyde transport via diffusion (lysosomall)
GENE_ASSOCIATION: (2271.1) GENE_LIST: 2271.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (440.1) or (440.3) or (440.2) GENE_LIST: 440.1 440.2 440.3 SUBSYSTEM: Alanine and Aspartate Metabolism
asparagine synthase (glutamine-hydrolysing)
GENE_ASSOCIATION: (5833.1) GENE_LIST: 5833.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (39.1) GENE_LIST: 39.1 SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (1638.1) GENE_LIST: 1638.1 SUBSYSTEM: Tyrosine metabolism
acyl-CoA oxidase (hexadecanoyl-CoA), peroxisomal
GENE_ASSOCIATION: (51.1) or (51.2) GENE_LIST: 51.1 51.2 SUBSYSTEM: Fatty Acid Metabolism
GENE_ASSOCIATION: (6999.1) GENE_LIST: 6999.1 SUBSYSTEM: Tryptophan metabolism
L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
galactose-1-phosphate uridylyltransferase
Cyanide transport via diffusion (extracellular to cytosol)
inositol-1,4,5-trisphosphate 5-phosphatase
CO2 endoplasmic reticular transport via diffusion
GENE_ASSOCIATION: (84532.1) GENE_LIST: 84532.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
primed glycogenin (glycogenin-8[1,4-Glc])
methylenetetrahydrofolate dehydrogenase (NADP), mitochondrial
GENE_ASSOCIATION: (6120.1) or (6120.2) GENE_LIST: 6120.1 6120.2 SUBSYSTEM: Pentose Phosphate Pathway
N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating)
GENE_ASSOCIATION: (54187.1) GENE_LIST: 54187.1 SUBSYSTEM: Aminosugar Metabolism
Malonyl-CoA Decarboxylase, mitochondrial
GENE_ASSOCIATION: (10682.1) GENE_LIST: 10682.1 SUBSYSTEM: Cholesterol Metabolism
folylpolyglutamate synthetase (10fthf), mitochondrial
GENE_ASSOCIATION: (5743.1) or (5742.1) GENE_LIST: 5742.1 5743.1 SUBSYSTEM: Eicosanoid Metabolism
Betaine transport (sodium symport) (2:1)
GENE_ASSOCIATION: (6539.1) GENE_LIST: 6539.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (9023.1) GENE_LIST: 9023.1 SUBSYSTEM: Bile Acid Biosynthesis
GENE_ASSOCIATION: (56474.1) or (56474.2) GENE_LIST: 56474.1 56474.2 SUBSYSTEM: Pyrimidine Biosynthesis
Propionyl-CoA carboxylase, mitochondrial
GENE_ASSOCIATION: (5096.1 and 5095.1) GENE_LIST: 5095.1 5096.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
keratan sulfate I, degradation product 1 exchange
GENE_ASSOCIATION: (4200.1) GENE_LIST: 4200.1 SUBSYSTEM: Pyruvate Metabolism
chloride transport via oxalate countertransport (2:1)
aldehyde dehydrogenase (acetaldehyde, NAD)
GENE_ASSOCIATION: (5130.1) or (9468.1) GENE_LIST: 5130.1 9468.1 SUBSYSTEM: Glycerophospholipid Metabolism
Tetradecanoate (n-C14:0) transport in via uniport
GENE_ASSOCIATION: (128.1) GENE_LIST: 128.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (65985.1) or (55902.2) or (55902.1) GENE_LIST: 55902.1 55902.2 65985.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
fatty acyl-CoA desaturase (n-C22:4CoA -> n-C22:5CoA)
5-Methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase
GENE_ASSOCIATION: (27232.1) GENE_LIST: 27232.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
3,4-Dihydroxyphenylacetaldehyde:NAD+ oxidoreductase
GENE_ASSOCIATION: (218.1) or (222.1) or (220.1) or (221.1) GENE_LIST: 218.1 220.1 221.1 222.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (1644.1) GENE_LIST: 1644.1 SUBSYSTEM: Phenylalanine metabolism
GENE_ASSOCIATION: (7306.1) GENE_LIST: 7306.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (2584.1) or (2585.2) or (2585.1) GENE_LIST: 2584.1 2585.1 2585.2 SUBSYSTEM: Galactose metabolism
purine-nucleoside phosphorylase (Deoxyadenosine)
L-ascorbate transport via proton symport
Phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase
GENE_ASSOCIATION: (11164.1) GENE_LIST: 11164.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (130013.1) GENE_LIST: 130013.1 SUBSYSTEM: Tryptophan metabolism
GENE_ASSOCIATION: (2821.1) GENE_LIST: 2821.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (435.1) GENE_LIST: 435.1 SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (8612.1) or (8611.1) or (8613.1) or (8611.2) GENE_LIST: 8611.1 8611.2 8612.1 8613.1 SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (47.1) or (47.2) GENE_LIST: 47.1 47.2 SUBSYSTEM: Citric Acid Cycle
1,3-Diaminopropane:oxygen oxidoreductase (deaminating)
GENE_ASSOCIATION: (8639.1) or (26.1) or (314.2) or (314.1) GENE_LIST: 26.1 314.1 314.2 8639.1 SUBSYSTEM: beta-Alanine metabolism
Acetoacetate decarboxylation (irreversible), mitochondrial
GENE_ASSOCIATION: (7372.1) GENE_LIST: 7372.1 SUBSYSTEM: Pyrimidine Biosynthesis
GENE_ASSOCIATION: (8694.1) or (84649.1) GENE_LIST: 84649.1 8694.1 SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (5106.1) GENE_LIST: 5106.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (206358.1) GENE_LIST: 206358.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (160728.1) GENE_LIST: 160728.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (221.1) or (218.1) or (220.1) GENE_LIST: 218.1 220.1 221.1 SUBSYSTEM: Tyrosine metabolism
3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase
nucleoside-diphosphate kinase (ATP:CDP), mitochondrial
GENE_ASSOCIATION: (112611.1) or (98.1) or (97.2) or (97.1) GENE_LIST: 112611.1 97.1 97.2 98.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (189.1) GENE_LIST: 189.1 SUBSYSTEM: Alanine and Aspartate Metabolism
alanine-glyoxylate transaminase (irreversible), (peroxisomal)
GENE_ASSOCIATION: (6818.1) or (6818.3) or (6818.2) GENE_LIST: 6818.1 6818.2 6818.3 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (6567.1) GENE_LIST: 6567.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (4942.1) GENE_LIST: 4942.1 SUBSYSTEM: Urea cycle/amino group metabolism
acyl-CoA dehydrogenase (butanoyl-CoA), mitochondrial
nucleoside-diphosphate kinase (ATP:dCDP), mitochondrial
Thiamine triphosphate transport in via anion antiport
Nicotinamide adenine dinucleotide phosphate
GENE_ASSOCIATION: (6646.1) GENE_LIST: 6646.1 SUBSYSTEM: Cholesterol Metabolism
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
GENE_ASSOCIATION: (124935.1) or (117247.1) GENE_LIST: 117247.1 124935.1 SUBSYSTEM: Transport, Extracellular
L-phenylalanine transport via diffusion (extracellular to cytosol)
24-dehydrocholesterol reductase [Precursor]
GENE_ASSOCIATION: (1718.1) GENE_LIST: 1718.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (3073.1 and 3074.1) or (3073.1) or (3074.1) GENE_LIST: 3073.1 3074.1 SUBSYSTEM: Hyaluronan Metabolism
GENE_ASSOCIATION: (1565.1) GENE_LIST: 1565.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (2222.1) GENE_LIST: 2222.1 SUBSYSTEM: Cholesterol Metabolism
phosphatidylinositol 4-phosphate 5-kinase
palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA)
GENE_ASSOCIATION: (3795.1) or (3795.2) GENE_LIST: 3795.1 3795.2 SUBSYSTEM: Fructose and Mannose Metabolism
Nicotinamide adenine dinucleotide phosphate - reduced
UDP-Glc endoplasmic reticulum transport via CMP antiport
fatty acyl-CoA desaturase (n-C22:5CoA -> n-C22:6CoA)
alcohol dehydrogenase (D-1,2-propanediol)
GENE_ASSOCIATION: (3706.1) or (80271.1) or (3707.1) GENE_LIST: 3706.1 3707.1 80271.1 SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (3290.1) or (3290.2) GENE_LIST: 3290.1 3290.2 SUBSYSTEM: Steroid Metabolism
11-beta-hydroxysteroid dehydrogenase type 1
GENE_ASSOCIATION: (2181.1) GENE_LIST: 2181.1 SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (116255.1) or (80168.1) GENE_LIST: 116255.1 80168.1 SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (7371.1) or (83549.1) GENE_LIST: 7371.1 83549.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (6566.1) or (9194.1) GENE_LIST: 6566.1 9194.1 SUBSYSTEM: Transport, Extracellular
acetoacetate transport via proton symport
GENE_ASSOCIATION: (5092.1) or (5092.2) GENE_LIST: 5092.1 5092.2 SUBSYSTEM: Tetrahydrobiopterin
Tetrahydrobiopterin-4a-carbinolamine dehydratase
GENE_ASSOCIATION: (4597.1) GENE_LIST: 4597.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (2571.1) or (2572.1) or (2571.2) GENE_LIST: 2571.1 2571.2 2572.1 SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (4860.1) GENE_LIST: 4860.1 SUBSYSTEM: NAD Metabolism
GENE_ASSOCIATION: (10935.1) or (2879.1) or (10935.2) GENE_LIST: 10935.1 10935.2 2879.1 SUBSYSTEM: Glutathione Metabolism
GENE_ASSOCIATION: (55512.1) or (55512.2) GENE_LIST: 55512.1 55512.2 SUBSYSTEM: Sphingolipid Metabolism
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
nucleoside-diphosphate kinase (ATP:dUDP)
L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase
GENE_ASSOCIATION: (3418.1) GENE_LIST: 3418.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (57026.1) GENE_LIST: 57026.1 SUBSYSTEM: Vitamin B6 Metabolism
GENE_ASSOCIATION: (8398.1) or (5320.1) or (8398.2) GENE_LIST: 5320.1 8398.1 8398.2 SUBSYSTEM: Glycerophospholipid Metabolism
L-1-Pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-Hydroxyglutamate semialdehyde, mitochondrial
glyceraldehyde-3-phosphate dehydrogenase
GENE_ASSOCIATION: (2597.1) or (26330.1) GENE_LIST: 2597.1 26330.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
GENE_ASSOCIATION: (22978.1) or (30833.1) GENE_LIST: 22978.1 30833.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (3417.1) GENE_LIST: 3417.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (26.1) or (314.1) or (8639.1) or (314.2) GENE_LIST: 26.1 314.1 314.2 8639.1 SUBSYSTEM: Arginine and Proline Metabolism
Putrescine:oxygen oxidoreductase (deaminating)
1-acylglycerol-3-phosphate O-acyltransferase 1
formaldehyde transport via diffusion (mitochondrial)
GENE_ASSOCIATION: (8228.1) GENE_LIST: 8228.1 SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (3612.1) or (3613.1) GENE_LIST: 3612.1 3613.1 SUBSYSTEM: Inositol Phosphate Metabolism
Gamma-glutamyl hydrolase (10FTHF7GLU), lysosomal
1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)
Cyanide sulfurtransferase, mitochondrial
GENE_ASSOCIATION: (7263.1) GENE_LIST: 7263.1 SUBSYSTEM: Cysteine Metabolism
GENE_ASSOCIATION: (1581.1) GENE_LIST: 1581.1 SUBSYSTEM: Bile Acid Biosynthesis
cytochrome P450, family 7, subfamily A, polypeptide 1
Dopamine 3-0-sulfate transport (diffusion)
GENE_ASSOCIATION: (26227.1) GENE_LIST: 26227.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
S-Adenosyl-L-homocysteine intracellular diffusion
L-2-aminoadipate shuttle (cytosol/mitochondria)
GENE_ASSOCIATION: (89874.1) GENE_LIST: 89874.1 SUBSYSTEM: Lysine Metabolism
dihydoorotic acid dehydrogenase (quinone10)
GENE_ASSOCIATION: (1723.1) GENE_LIST: 1723.1 SUBSYSTEM: Pyrimidine Biosynthesis
GENE_ASSOCIATION: (51166.1) or (51166.2) GENE_LIST: 51166.1 51166.2 SUBSYSTEM: Lysine Metabolism
2-aminoadipate transaminase, irreversible
GENE_ASSOCIATION: (80308.1) or (80308.2) GENE_LIST: 80308.1 80308.2 SUBSYSTEM: Riboflavin Metabolism
alpha-amylase, extracellular (strch1 -> strch2)
L-glutamine transport via electroneutral transporter
GENE_ASSOCIATION: (1806.1) GENE_LIST: 1806.1 SUBSYSTEM: Pyrimidine Catabolism
Gamma-glutamyl hydrolase (5DHF), extracellular
Nicotinamide adenine dinucleotide - reduced
GENE_ASSOCIATION: (53630.1) GENE_LIST: 53630.1 SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (5019.1) or (64064.1) GENE_LIST: 5019.1 64064.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (26289.1) or (26289.2) GENE_LIST: 26289.1 26289.2 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (2542.1) GENE_LIST: 2542.1 SUBSYSTEM: Transport, Endoplasmic Reticular
glucose 6-phosphate endoplasmic reticular transport via diffusion
GENE_ASSOCIATION: (8608.1) or (5959.1) GENE_LIST: 5959.1 8608.1 SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (171425.1) or (171425.2) GENE_LIST: 171425.1 171425.2 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (2582.1) or (2582.2) GENE_LIST: 2582.1 2582.2 SUBSYSTEM: Galactose metabolism
L-carnitine inward transport by Na+ symport
GENE_ASSOCIATION: (6476.1) or (8972.1) GENE_LIST: 6476.1 8972.1 SUBSYSTEM: Galactose metabolism
sucrose hydrolyzing enxyme, extracellular
3-Methyl-2-oxopentanoate mitochondrial transport via proton symport
L-ascorbate transport via facilitated diffusion
GENE_ASSOCIATION: (2806.1) GENE_LIST: 2806.1 SUBSYSTEM: Alanine and Aspartate Metabolism
2-keto-4-methylthiobutyrate transamination
choline transport via diffusion (cytosol to mitochondria)
GENE_ASSOCIATION: (92745.1) or (10991.1) GENE_LIST: 10991.1 92745.1 SUBSYSTEM: Transport, Extracellular
Thiamine transport in via proton antiport
GENE_ASSOCIATION: (80704.1) or (10560.1) GENE_LIST: 10560.1 80704.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (10993.1) GENE_LIST: 10993.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
GENE_ASSOCIATION: (2224.1) GENE_LIST: 2224.1 SUBSYSTEM: Cholesterol Metabolism
5-Aminolevulinate mitochondrial transport
GENE_ASSOCIATION: (8394.1) or (23396.1) or (8395.1) GENE_LIST: 23396.1 8394.1 8395.1 SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol 3,4-bisphosphate 5-kinase
GENE_ASSOCIATION: (60482.1) GENE_LIST: 60482.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (197257.1) or (197257.2) GENE_LIST: 197257.1 197257.2 SUBSYSTEM: Pyruvate Metabolism
L-proline reversible transport via proton symport
taurine transport (sodium symport) (cytosol to peroxisome)
GENE_ASSOCIATION: (6533.1) GENE_LIST: 6533.1 SUBSYSTEM: Taurine and hypotaurine metabolism
delta1-piperideine-2-carboxylate reductase, perixosomal
GENE_ASSOCIATION: (3177.1) or (2030.1) GENE_LIST: 2030.1 3177.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (8802.1 and 8803.1) GENE_LIST: 8802.1 8803.1 SUBSYSTEM: C5-Branched dibasic acid metabolism
Itaconate--CoA ligase (ADP-forming), mitochondrial
GENE_ASSOCIATION: (686.1) GENE_LIST: 686.1 SUBSYSTEM: Biotin Metabolism
GENE_ASSOCIATION: (64849.1) or (64849.2) GENE_LIST: 64849.1 64849.2 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2954.1) or (2954.3) or (2954.2) GENE_LIST: 2954.1 2954.2 2954.3 SUBSYSTEM: Tyrosine metabolism
bilirubin monoglucuronide transport via bicarbonate countertransport
GENE_ASSOCIATION: (10599.1) or (28234.1) GENE_LIST: 10599.1 28234.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (23530.2) or (23530.1) GENE_LIST: 23530.1 23530.2 SUBSYSTEM: NAD Metabolism
transport into the mitochondria from cytosol (carnitine)
nucleoside-diphosphatase (GDP), extracellular
3-sulfino-alanine transaminase (irreversible)
GENE_ASSOCIATION: (5834.1) or (5837.1) or (5836.1) GENE_LIST: 5834.1 5836.1 5837.1 SUBSYSTEM: Starch and Sucrose Metabolism
glycogen phosphorylase (glygn2 -> dxtrn)
GENE_ASSOCIATION: (3939.1) GENE_LIST: 3939.1 SUBSYSTEM: Pyruvate Metabolism
Glycine betaine transport via diffusion (mitochondria to cytosol)
GENE_ASSOCIATION: (51477.1) GENE_LIST: 51477.1 SUBSYSTEM: Inositol Phosphate Metabolism
glucuronate endoplasmic reticular transport
SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
GENE_ASSOCIATION: (3156.1) GENE_LIST: 3156.1 SUBSYSTEM: Cholesterol Metabolism
Hydroxymethylglutaryl CoA reductase (ir)
Fumarate:thiosulfate antiport, mitochondrial
Nitric Oxide Synthase (intermediate forming)
inositol-1,3,4,5-trisphosphate 5-phosphatase
L-sulfolactate transport (cytosol to extracellular)
GENE_ASSOCIATION: (130752.1) or (4190.1) GENE_LIST: 130752.1 4190.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (18.1) or (18.2) GENE_LIST: 18.1 18.2 SUBSYSTEM: beta-Alanine metabolism
3-Aminopropanoate:2-oxoglutarate aminotransferase (m)
L-methionine transport in via sodium symport
GENE_ASSOCIATION: (1644.1) or (3067.1) GENE_LIST: 1644.1 3067.1 SUBSYSTEM: Histidine Metabolism
GENE_ASSOCIATION: (2235.1) or (2235.2) GENE_LIST: 2235.1 2235.2 SUBSYSTEM: Heme Biosynthesis
N-Methylhistamine:oxygen oxidoreductase (deaminating)
GENE_ASSOCIATION: (26.1) or (314.1) or (8639.1) or (314.2) GENE_LIST: 26.1 314.1 314.2 8639.1 SUBSYSTEM: Histidine Metabolism
pentadecanoate transport into the mitochondria
hypoxanthine phosphoribosyltransferase (Hypoxanthine)
GENE_ASSOCIATION: (3251.1) GENE_LIST: 3251.1 SUBSYSTEM: Salvage Pathway
GENE_ASSOCIATION: (132.1) or (132.2) GENE_LIST: 132.1 132.2 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (2632.1) GENE_LIST: 2632.1 SUBSYSTEM: Starch and Sucrose Metabolism
1,4-alpha-glucan branching enzyme (glygn1 -> glygn2)
GENE_ASSOCIATION: (10257.1) GENE_LIST: 10257.1 SUBSYSTEM: Transport, Extracellular
prostaglandine E1 transport (ATP-dependent)
GENE_ASSOCIATION: (6675.1) or (91373.1) GENE_LIST: 6675.1 91373.1 SUBSYSTEM: Aminosugar Metabolism
fatty acyl-CoA desaturase (n-C20:3CoA -> n-C20:4CoA)
GENE_ASSOCIATION: (6513.1) or (6515.1) or (6514.1) GENE_LIST: 6513.1 6514.1 6515.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (9380.1) GENE_LIST: 9380.1 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (3157.2) or (3157.1) GENE_LIST: 3157.1 3157.2 SUBSYSTEM: Cholesterol Metabolism
hydrogen peroxide lysosomal transport via diffusion
GENE_ASSOCIATION: (115584.1) GENE_LIST: 115584.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (4507.1) GENE_LIST: 4507.1 SUBSYSTEM: Arginine and Proline Metabolism
Gamma-glutamyl hydrolase (7DHF), lysosomal
Gamma-glutamyl hydrolase (5THF), extracellular
GENE_ASSOCIATION: (26873.1) GENE_LIST: 26873.1 SUBSYSTEM: Glutathione Metabolism
5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)
dimethylglycine transport via diffusion (cytosol to mitochondria)
L-lactate reversible transport via proton symport
GENE_ASSOCIATION: (56953.1) GENE_LIST: 56953.1 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (23475.1) GENE_LIST: 23475.1 SUBSYSTEM: NAD Metabolism
nicotinate-nucleotide diphosphorylase (carboxylating)
GENE_ASSOCIATION: (32.1) GENE_LIST: 32.1 SUBSYSTEM: Fatty Acid Metabolism
ribonucleoside-diphosphate reductase (UDP)
GENE_ASSOCIATION: (443.1) or (91703.1) GENE_LIST: 443.1 91703.1 SUBSYSTEM: Alanine and Aspartate Metabolism
7-alpha,25-Dihydroxycholesterol exchange
UDP-glucuronosyltransferase 1-10 precursor, microsomal (13-cis)
GENE_ASSOCIATION: (54576.1) or (54575.1) GENE_LIST: 54575.1 54576.1 SUBSYSTEM: Vitamin A Metabolism
GENE_ASSOCIATION: (2655.1) GENE_LIST: 2655.1 SUBSYSTEM: Glutathione Metabolism
guanosine facilated transport in cytosol
chloride transport via hydroxide countertransport (2:1)
inositol 1,4-bisphosphate nuclear transport (diffusion)
GENE_ASSOCIATION: (2110.1) GENE_LIST: 2110.1 SUBSYSTEM: Fatty acid oxidation
Electron transfer flavoprotein-ubiquinone oxidoreductase
SUBSYSTEM: Glycerophospholipid Metabolism
Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)
nucleoside-diphosphate kinase (ATP:GDP), nuclear
GENE_ASSOCIATION: (4353.1) GENE_LIST: 4353.1 SUBSYSTEM: Miscellaneous
nucleoside-diphosphate kinase (ATP:IDP), nuclear
GENE_ASSOCIATION: (8309.1) GENE_LIST: 8309.1 SUBSYSTEM: Bile Acid Biosynthesis
acyl-Coenzyme A oxidase 2, branched chain
Tyramine O-sulfate transport (diffusion)
mesaconate--CoA ligase (ADP-forming), mitochondrial
nucleoside-diphosphatase (UDP), endoplasmic reticulum
GENE_ASSOCIATION: (5337.1) GENE_LIST: 5337.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (10797.1) GENE_LIST: 10797.1 SUBSYSTEM: Folate Metabolism
methylenetetrahydrofolate dehydrogenase (NAD), mitochondrial
GENE_ASSOCIATION: (8501.1) or (124935.1) GENE_LIST: 124935.1 8501.1 SUBSYSTEM: Transport, Extracellular
L-valine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (7358.1) GENE_LIST: 7358.1 SUBSYSTEM: Starch and Sucrose Metabolism
aminomuconate-semialdehyde dehydrogenase
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
5,6,7,8-Tetrahydrofolate transport, diffusion, lysosomal
GENE_ASSOCIATION: (26289.2) or (26289.1) GENE_LIST: 26289.1 26289.2 SUBSYSTEM: Nucleotides
L-phenylalanine transport in via sodium symport
GENE_ASSOCIATION: (52.1) or (52.3) or (52.2) GENE_LIST: 52.1 52.2 52.3 SUBSYSTEM: Riboflavin Metabolism
L-glutamate 5-semialdehyde dehydratase, reversible, mitochondrial
Beta-alanine reversible mitochondrial transport (diffusion)
GENE_ASSOCIATION: (4200.1) or (10873.1) GENE_LIST: 10873.1 4200.1 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (50808.1) GENE_LIST: 50808.1 SUBSYSTEM: Nucleotides
3MLDA extracellular transport via diffusion
nucleoside-diphosphate kinase (ATP:dTDP)
GENE_ASSOCIATION: (5051.1) or (5049.1 and 5050.1) or (5049.1 and 5050.1 and 5048.1) GENE_LIST: 5048.1 5049.1 5050.1 5051.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (58510.1) GENE_LIST: 58510.1 SUBSYSTEM: Arginine and Proline Metabolism
GENE_ASSOCIATION: (4190.1) or (130752.1) GENE_LIST: 130752.1 4190.1 SUBSYSTEM: Cysteine Metabolism
phosphatidylinositol 4-phosphate 3-kinase
GENE_ASSOCIATION: (2747.1) or (2746.1) GENE_LIST: 2746.1 2747.1 SUBSYSTEM: Glutamate metabolism
glutamate dehydrogenase (NADP), mitochondrial
nucleoside-diphosphate kinase (ATP:dIDP), nuclear
GENE_ASSOCIATION: (3158.1) GENE_LIST: 3158.1 SUBSYSTEM: Cholesterol Metabolism
Beta oxidation of med/long chain fatty acid
GENE_ASSOCIATION: (2180.1) or (2181.2) or (2181.1) GENE_LIST: 2180.1 2181.1 2181.2 SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (219.1) or (217.1) GENE_LIST: 217.1 219.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
aldehyde dehydrogenase (acetylaldehyde, NAD), mitochondrial
NADPH transporter, endoplasmic reticulum
Gamma-glutamyl hydrolase (6THF), lysosomal
uroporphyrinogen decarboxylase (uroporphyrinogen III)
GENE_ASSOCIATION: (7389.1) GENE_LIST: 7389.1 SUBSYSTEM: Heme Biosynthesis
GENE_ASSOCIATION: (7298.1) GENE_LIST: 7298.1 SUBSYSTEM: Nucleotides
L-arginine transport via diffusion (extracellular to cytosol)
GENE_ASSOCIATION: (55312.1) GENE_LIST: 55312.1 SUBSYSTEM: Riboflavin Metabolism
coproporphyrinogen oxidase (O2 required)
GENE_ASSOCIATION: (1371.1) GENE_LIST: 1371.1 SUBSYSTEM: Heme Biosynthesis
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
GENE_ASSOCIATION: (4860.1) GENE_LIST: 4860.1 SUBSYSTEM: Nucleotides
purine-nucleoside phosphorylase (Xanthosine)
GENE_ASSOCIATION: (847.1) GENE_LIST: 847.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate), mitochondrial
dimethylglycine dehydrogenase, mitochondrial
GENE_ASSOCIATION: (29958.1) GENE_LIST: 29958.1 SUBSYSTEM: Glycine, Serine, and Threonine Metabolism
3-hydroxyacyl-CoA dehydratase (3-hydroxyisobutyryl-CoA) (mitochondria)
GENE_ASSOCIATION: (2805.1) GENE_LIST: 2805.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (79901.1) GENE_LIST: 79901.1 SUBSYSTEM: Heme Biosynthesis
clupanodonic acid (docosapentaenoic (n-3)) exchange
purine-nucleoside phosphorylase (Guanosine)
GENE_ASSOCIATION: (3034.1) GENE_LIST: 3034.1 SUBSYSTEM: Histidine Metabolism
nucleoside-diphosphate kinase (ATP:dCDP)
nucleoside-diphosphatase (IDP), extracellular
GENE_ASSOCIATION: (36.1) or (34.1) GENE_LIST: 34.1 36.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
acyl-CoA dehydrogenase (2-methylbutanoyl-CoA), mitochondrial
GENE_ASSOCIATION: (34.1) or (27034.1) GENE_LIST: 27034.1 34.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
acyl-CoA dehydrogenase (isobutyryl-CoA), mitochondrial
GENE_ASSOCIATION: (54575.1) or (54576.1) GENE_LIST: 54575.1 54576.1 SUBSYSTEM: Steroid Metabolism
GENE_ASSOCIATION: (3628.1) GENE_LIST: 3628.1 SUBSYSTEM: Inositol Phosphate Metabolism
inositol-1,3,4-trisphosphate 1-phosphatase
nucleoside-diphosphate kinase (ATP:CDP),nuclear
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
GENE_ASSOCIATION: (5728.1) GENE_LIST: 5728.1 SUBSYSTEM: Inositol Phosphate Metabolism
5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial
L-aminoadipate-semialdehyde dehydrogenase (NADH), mitochondrial
GENE_ASSOCIATION: (2109.2) and (2108.1) or (2109.1) and (2108.1) GENE_LIST: 2108.1 2109.1 2109.2 SUBSYSTEM: Fatty acid oxidation
GENE_ASSOCIATION: (56922.1 and 64087.1) GENE_LIST: 56922.1 64087.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
methylcrotonoyl-CoA carboxylase, mitochondrial
4-Hydroxyphenylpyruvate:oxygen oxidoreductase
GENE_ASSOCIATION: (3242.1) GENE_LIST: 3242.1 SUBSYSTEM: Tyrosine metabolism
dihomo-gamma-linolenic acid (n-6) exchange
choline phosphate intracellular transport
Choline transport, nuclear through pores
GENE_ASSOCIATION: (3658.1) or (48.1) GENE_LIST: 3658.1 48.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (54363.1) or (51179.2) or (51179.1) GENE_LIST: 51179.1 51179.2 54363.1 SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
alpha-N-Phenylacetyl-L-glutamine exchange
GENE_ASSOCIATION: (8564.1) GENE_LIST: 8564.1 SUBSYSTEM: Tryptophan metabolism
Nicotinamide adenine dinucleotide phosphate exchange
1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)
GENE_ASSOCIATION: (6570.1) or (6571.1) GENE_LIST: 6570.1 6571.1 SUBSYSTEM: Transport, Extracellular
Adrenaline secretion via secretory vesicle (ATP driven)
1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)
GENE_ASSOCIATION: (158.1) or (158.2) GENE_LIST: 158.1 158.2 SUBSYSTEM: Nucleotides
GENE_ASSOCIATION: (5167.1) or (5169.1) or (5168.1) GENE_LIST: 5167.1 5168.1 5169.1 SUBSYSTEM: Starch and Sucrose Metabolism
GENE_ASSOCIATION: (3162.1) or (3163.1) GENE_LIST: 3162.1 3163.1 SUBSYSTEM: Heme Degradation
S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
GENE_ASSOCIATION: (3176.1) GENE_LIST: 3176.1 SUBSYSTEM: Histidine Metabolism
pantetheine-phosphate adenylyltransferase
saccharopine dehydrogenase (NADP, L-lysine forming), mitochondrial
GENE_ASSOCIATION: (10157.1) GENE_LIST: 10157.1 SUBSYSTEM: Lysine Metabolism
GENE_ASSOCIATION: (23236.2) or (23236.1) GENE_LIST: 23236.1 23236.2 SUBSYSTEM: Inositol Phosphate Metabolism
phosphatidylinositol 4-phosphate phospholipase C, nucleus
S-Adenosyl-L-methionine:catechol O-methyltransferase
GENE_ASSOCIATION: (118881.1) GENE_LIST: 118881.1 SUBSYSTEM: Tyrosine metabolism
dihydrofolate reversible mitochondrial transport
fatty acyl-CoA desaturase (n-C24:5CoA -> n-C24:6CoA)
GENE_ASSOCIATION: (1571.1) GENE_LIST: 1571.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (2628.1) GENE_LIST: 2628.1 SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (4860.1) or (151531.1) GENE_LIST: 151531.1 4860.1 SUBSYSTEM: Nucleotides
1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)
GENE_ASSOCIATION: (1491.1) or (1491.2) GENE_LIST: 1491.1 1491.2 SUBSYSTEM: Cysteine Metabolism
starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]}) exchange
phosphatidylinositol 4,5-bisphosphate (Homo sapiens)
GENE_ASSOCIATION: (383.1) GENE_LIST: 383.1 SUBSYSTEM: Urea cycle/amino group metabolism
phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)
phosphatidylinositol-3,4-bisphosphate (Homo sapiens)
GENE_ASSOCIATION: (34.1) or (34.1) or (35.1) or (35.1) GENE_LIST: 34.1 35.1 SUBSYSTEM: Fatty acid oxidation
phosphatidylinositol-3,5-bisphosphate (Homo sapiens)
carnitine-acetylcarnitine carrier, peroxisomal
L-lactate reversible transport via sodium symport
Iodide:hydrogen-peroxide oxidoreductase 3
fatty acyl-CoA synthase (n-C8:0CoA), lumped reaction
hyaluronan biosynthesis, precursor 1 exchange
GENE_ASSOCIATION: (79717.1) GENE_LIST: 79717.1 SUBSYSTEM: CoA Biosynthesis
nucleoside-diphosphate kinase (ATP:dADP), mitochondrial
SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (6309.1) GENE_LIST: 6309.1 SUBSYSTEM: Cholesterol Metabolism
GENE_ASSOCIATION: (55577.1) GENE_LIST: 55577.1 SUBSYSTEM: Aminosugar Metabolism
GENE_ASSOCIATION: (366.1) GENE_LIST: 366.1 SUBSYSTEM: Urea cycle/amino group metabolism
GENE_ASSOCIATION: (7390.1) GENE_LIST: 7390.1 SUBSYSTEM: Heme Biosynthesis
L-aspartate transport via Na, H symport and K antiport
sphingosylphosphorylcholine (homo sapiens) exchange
GENE_ASSOCIATION: (223.1) GENE_LIST: 223.1 SUBSYSTEM: beta-Alanine metabolism
GENE_ASSOCIATION: (6821.1) GENE_LIST: 6821.1 SUBSYSTEM: Cysteine Metabolism
Glutamate transport via Na, H symport and K antiport
GENE_ASSOCIATION: (11001.1) GENE_LIST: 11001.1 SUBSYSTEM: Fatty acid activation
3-hydroxyacyl-CoA dehydrogenase (2-Methylacetoacetyl-CoA), mitochondrial
GENE_ASSOCIATION: (3028.1) GENE_LIST: 3028.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
GENE_ASSOCIATION: (51179.1) or (54363.1) or (51179.2) GENE_LIST: 51179.1 51179.2 54363.1 SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
glycine-cleavage complex (lipoylprotein) irreversible, mitochondrial
nucleoside-diphosphate kinase (ATP:GDP), mitochondrial
L-lysine transport, peroxisomal (irreversible)
L-leucine transport via diffusion (extracellular to cytosol)
nucleoside-diphosphatase (UDP), extracellular
ethanol reversible peroxisomal transport
cholate transport via sodium cotransport
GENE_ASSOCIATION: (6554.1) or (6555.1) GENE_LIST: 6554.1 6555.1 SUBSYSTEM: Transport, Extracellular
D-galactose transport via proton symport
GENE_ASSOCIATION: (55191.1) GENE_LIST: 55191.1 SUBSYSTEM: NAD Metabolism
glucose 6-phosphate dehydrogenase, endoplasmic reticulum
carnitine-propcarnitine carrier, peroxisomal
GENE_ASSOCIATION: (788.1) or (788.1) GENE_LIST: 788.1 SUBSYSTEM: Carnitine shuttle
alkyl glycerol phosphocholine acetyl transferase
GENE_ASSOCIATION: (54576.1) GENE_LIST: 54576.1 SUBSYSTEM: Steroid Metabolism
acetone mitochondrial transport via proton symport
GENE_ASSOCIATION: (549.1) or (3030.1) and (3032.1) or (1892.1) GENE_LIST: 1892.1 3030.1 3032.1 549.1 SUBSYSTEM: Tryptophan metabolism
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA) (mitochondria)
GENE_ASSOCIATION: (34.1) GENE_LIST: 34.1 SUBSYSTEM: Fatty acid oxidation
Beta oxidation of long chain fatty acid (odd chain)
uracil transport via facilated diffusion
acyl-CoA dehydrogenase (isovaleryl-CoA), mitochondrial
GENE_ASSOCIATION: (3712.1) GENE_LIST: 3712.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
PHEACGLN extracellular transport via diffusion
purine-nucleoside phosphorylase (Adenosine)
lysophosphatidylcholine (homo sapiens) exchange
GENE_ASSOCIATION: (80150.1) GENE_LIST: 80150.1 SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (10400.2) or (10400.1) or (10400.3) GENE_LIST: 10400.1 10400.2 10400.3 SUBSYSTEM: Glycerophospholipid Metabolism
phosphatidylethanolamine N-methyltransferase
Acetoacetate mitochondrial transport via H+ symport
GENE_ASSOCIATION: (226.2) or (229.1) or (226.3) or (230.1) or (226.1) GENE_LIST: 226.1 226.2 226.3 229.1 230.1 SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
2-keto-3deoxy-D-glycero-D-galactononic acid phosphohydrolase
nucleoside-diphosphate kinase (ATP:dADP), nuclear
GENE_ASSOCIATION: (64841.1) GENE_LIST: 64841.1 SUBSYSTEM: Aminosugar Metabolism
N-acetylglucosamine-6-phosphate synthase
GENE_ASSOCIATION: (1572.1) GENE_LIST: 1572.1 SUBSYSTEM: CYP Metabolism
GENE_ASSOCIATION: (50.1) GENE_LIST: 50.1 SUBSYSTEM: Citric Acid Cycle
GENE_ASSOCIATION: (6583.1) GENE_LIST: 6583.1 SUBSYSTEM: Transport, Extracellular
L-carnitine outward transport (H+ antiport)
norepinephrine sulfate transport (diffusion)
GENE_ASSOCIATION: (162466.1) GENE_LIST: 162466.1 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (4953.1) GENE_LIST: 4953.1 SUBSYSTEM: Urea cycle/amino group metabolism
phosphopantothenoylcysteine decarboxylase
GENE_ASSOCIATION: (60490.1) GENE_LIST: 60490.1 SUBSYSTEM: CoA Biosynthesis
nucleoside-diphosphate kinase (ATP:dTDP), nuclear
starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]}) exchange
GENE_ASSOCIATION: (8574.1) or (231.1) or (10327.2) or (10327.1) GENE_LIST: 10327.1 10327.2 231.1 8574.1 SUBSYSTEM: Fructose and Mannose Metabolism
GENE_ASSOCIATION: (2544.1) GENE_LIST: 2544.1 SUBSYSTEM: Transport, Endoplasmic Reticular
phosphate transport, endoplasmic reticulum
aspartate N-acetyltransferase, mitochondrial
SUBSYSTEM: Alanine and Aspartate Metabolism
GENE_ASSOCIATION: (1384.1) GENE_LIST: 1384.1 SUBSYSTEM: Carnitine shuttle
saccharopine dehydrogenase (NAD, L-glutamate forming), mitochondrial
Gamma-glutamyl hydrolase (7THF), lysosomal
GENE_ASSOCIATION: (66002.1) GENE_LIST: 66002.1 SUBSYSTEM: CYP Metabolism
ornithine mitochondrial transport exchange with citruline
GENE_ASSOCIATION: (10166.1) or (83884.1) GENE_LIST: 10166.1 83884.1 SUBSYSTEM: Transport, Mitochondrial
GENE_ASSOCIATION: (427.1) or (427.2) GENE_LIST: 427.1 427.2 SUBSYSTEM: Sphingolipid Metabolism
GENE_ASSOCIATION: (3795.1) or (3795.2) GENE_LIST: 3795.1 3795.2 SUBSYSTEM: Glyoxylate and Dicarboxylate Metabolism
GENE_ASSOCIATION: (6565.1) GENE_LIST: 6565.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (5464.1) GENE_LIST: 5464.1 SUBSYSTEM: Oxidative Phosphorylation
GENE_ASSOCIATION: (2875.1) or (84706.1) GENE_LIST: 2875.1 84706.1 SUBSYSTEM: Glutamate metabolism
oxalate transport via bicarbonate countertransport
GENE_ASSOCIATION: (7083.1) or (7084.1) GENE_LIST: 7083.1 7084.1 SUBSYSTEM: Nucleotides
phosphatidylinositol synthase (Homo sapiens)
GENE_ASSOCIATION: (10423.2) or (10423.1) GENE_LIST: 10423.1 10423.2 SUBSYSTEM: Glycerophospholipid Metabolism
GENE_ASSOCIATION: (7378.2) or (151531.1) or (7378.1) GENE_LIST: 151531.1 7378.1 7378.2 SUBSYSTEM: Pyrimidine Catabolism
pyrimidine-nucleoside phosphorylase (uracil)
methylmalonate-semialdehyde dehydrogenase (malonic semialdehyde), mitochondrial
GENE_ASSOCIATION: (4329.1) GENE_LIST: 4329.1 SUBSYSTEM: Propanoate Metabolism
GENE_ASSOCIATION: (5244.1) or (5244.3) or (5244.2) GENE_LIST: 5244.1 5244.2 5244.3 SUBSYSTEM: Transport, Extracellular
glucose transport, endoplasmic reticulum
aldehyde dehydrogenase (phenylacetaldehyde, NADP)
2,3,4,5-Tetrahydropyridine-2-carboxylate transport, peroxisomal
D-glucurono-6,3-lactone transport, endoplasmic reticulum
Gamma-glutamyl hydrolase (6DHF), lysosomal
GENE_ASSOCIATION: (19.1) GENE_LIST: 19.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (89874.1) GENE_LIST: 89874.1 SUBSYSTEM: Tryptophan metabolism
2-oxoadipate shuttle (cytosol/mitochondria)
O-acetylcarnintine transport into mitochondria via diffusion
GENE_ASSOCIATION: (2184.1) GENE_LIST: 2184.1 SUBSYSTEM: Tyrosine metabolism
GENE_ASSOCIATION: (2752.1) or (51557.1) GENE_LIST: 2752.1 51557.1 SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (50487.1) GENE_LIST: 50487.1 SUBSYSTEM: Triacylglycerol Synthesis
GENE_ASSOCIATION: (7357.1) GENE_LIST: 7357.1 SUBSYSTEM: Sphingolipid Metabolism
malonate-semialdehyde dehydrogenase (acetylating), mitochondrial
arginine mitochondrial transport via ornithine carrier
5-formyltetrahydrofolate transport via anion exchange
GENE_ASSOCIATION: (34.1) or (35.1) GENE_LIST: 34.1 35.1 SUBSYSTEM: Fatty acid activation
nucleoside-diphosphate kinase (ATP:dTDP), mitochondrial
GENE_ASSOCIATION: (5226.1) GENE_LIST: 5226.1 SUBSYSTEM: Pentose Phosphate Pathway
GENE_ASSOCIATION: (1571.1) GENE_LIST: 1571.1 SUBSYSTEM: Glycolysis/Gluconeogenesis
phosphatidylinositol 4-phosphate nuclear transport (diffusion)
Gamma-glutamyl hydrolase (10FTHF6GLU), lysosomal
fatty-acid--CoA ligase (butanoate), mitochondrial
GENE_ASSOCIATION: (116285.1) GENE_LIST: 116285.1 SUBSYSTEM: Fatty acid activation
GENE_ASSOCIATION: (4199.1) GENE_LIST: 4199.1 SUBSYSTEM: Pyruvate Metabolism
GENE_ASSOCIATION: (5238.1) GENE_LIST: 5238.1 SUBSYSTEM: Aminosugar Metabolism
GENE_ASSOCIATION: (6888.1) GENE_LIST: 6888.1 SUBSYSTEM: Pentose Phosphate Pathway
L-glutamate reversible transport via proton symport, mitochondrial
phosphate transport in/out via two Na+ symporter
GENE_ASSOCIATION: (142680.1) GENE_LIST: 142680.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (38.1) GENE_LIST: 38.1 SUBSYSTEM: Valine, Leucine, and Isoleucine Metabolism
L-isoleucine transport via diffusion (extracellular to cytosol)
4-aminobutyrate transaminase, reversible (mitochondrial)
GENE_ASSOCIATION: (18.1) or (18.2) GENE_LIST: 18.1 18.2 SUBSYSTEM: Glutamate metabolism
GENE_ASSOCIATION: (23498.1) GENE_LIST: 23498.1 SUBSYSTEM: Tryptophan metabolism
glutamate dehydrogenase (NAD) (mitochondrial)
cholesterol precursor intracellular transport
Lysine mitochondrial transport via ornithine carrier
phosphatidylglycerol (homo sapiens) exchange
GENE_ASSOCIATION: (10841.1) or (10841.2) GENE_LIST: 10841.1 10841.2 SUBSYSTEM: Histidine Metabolism
2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxopentanoate), mitochondrial
GENE_ASSOCIATION: (445.1) or (445.2) GENE_LIST: 445.1 445.2 SUBSYSTEM: Alanine and Aspartate Metabolism
bilirubin transport via bicarbonate countertransport
GENE_ASSOCIATION: (10599.1) GENE_LIST: 10599.1 SUBSYSTEM: Transport, Extracellular
GENE_ASSOCIATION: (2519.1) GENE_LIST: 2519.1 SUBSYSTEM: Keratan sulfate degradation
GENE_ASSOCIATION: (1036.1) GENE_LIST: 1036.1 SUBSYSTEM: Taurine and hypotaurine metabolism
1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens) exchange
GENE_ASSOCIATION: (55586.1) GENE_LIST: 55586.1 SUBSYSTEM: Inositol Phosphate Metabolism
GENE_ASSOCIATION: (51733.1) GENE_LIST: 51733.1 SUBSYSTEM: Pyrimidine Catabolism