761683
stoichiometry: 6.0
species: 735445
type: SpeciesReference

736438
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dIDP_C10H11N4O10P2
type: Species

746061
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Mannose_C6H12O6
type: Species

778203
stoichiometry: 1.0
species: 747698
type: SpeciesReference

742055
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 15_C49H71N2O57S5
type: Species

741524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hexadecenoate (n-C16:1)_C16H29O2
type: Species

817559
stoichiometry: 2.0
species: 741283
type: SpeciesReference

777336
stoichiometry: 1.0
species: 737774
type: SpeciesReference

849200
stoichiometry: 1.0
species: 734513
type: SpeciesReference

038148
product: 826784
is: ENSCAFG00000020362.2
name: _11-beta-hydroxysteroid dehydrogenase type 2
type: Reaction
reversible: true
product: 826796
reactant: 826748
fast: false
notes: R_HSD11B2r subsystem: Steroid Metabolism R_HSD11B2r equation: [r] : cortsn + h + nadh <==> crtsl + nad
reactant: 826760
reactant: 826772

038355
reactant: 828290
product: 828327
reversible: false
is: http://identifiers.org/ec-code/2.4.1.22
product: 828339
type: Reaction
is: ENSCAFG00000008950.2
fast: false
name: UDPgalactose:D-glucose 4-beta-D-galactosyltransferase, Golgi apparatus
product: 828314
notes: R_UGALGTg subsystem: Galactose metabolism R_UGALGTg equation: [g] : glc-D + udpgal --> h + lcts + udp
reactant: 828302

738738
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Type IIIH glycolipid_C70H122N3O40FULLRCO
type: Species

807639
stoichiometry: 1.0
species: 741199
type: SpeciesReference

756593
stoichiometry: 1.0
species: 733419
type: SpeciesReference

810639
stoichiometry: 1.0
species: 730874
type: SpeciesReference

826037
stoichiometry: 1.0
species: 729307
type: SpeciesReference

842996
stoichiometry: 1.0
species: 736898
type: SpeciesReference

035565
name: _3-oxoacid CoA-transferase
type: Reaction
product: 801330
reversible: true
is: ENSCAFG00000018589.2
reactant: 801305
product: 801318
notes: R_OCOAT1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OCOAT1m equation: [m] : acac + succoa <==> aacoa + succ
fast: false
reactant: 801293
is: http://identifiers.org/ec-code/2.8.3.5

816861
stoichiometry: 1.0
species: 730862
type: SpeciesReference

811578
stoichiometry: 5.0
species: 731549
type: SpeciesReference

729726
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S
type: Species

790786
stoichiometry: 1.0
species: 746978
type: SpeciesReference

837255
stoichiometry: 2.0
species: 741332
type: SpeciesReference

740144
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glyoxylate_C2H1O3
type: Species

851225
stoichiometry: 2.0
species: 749502
type: SpeciesReference

038429
reactant: 829109
reactant: 829121
type: Reaction
product: 829181
is: ENSCAFG00000025205.1
notes: R_HKt subsystem: Transport, Extracellular R_HKt equation: atp[c] + h2o[c] + k[e] --> adp[c] + h[e] + k[c] + pi[c]
product: 829145
is: ENSCAFG00000006951.2
is: http://identifiers.org/ec-code/3.6.3.10
name: H+/K+ gastric/non-gastric P-ATPase and ABC ATPase
product: 829169
is: ENSCAFG00000006390.2
fast: false
reversible: false
product: 829157
is: ENSCAFG00000012174.2
reactant: 829133

823684
stoichiometry: 9.0
species: 733189
type: SpeciesReference

726428
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (R)-Propane-1,2-diol_C3H8O2
type: Species

837952
stoichiometry: 4.0
species: 741259
type: SpeciesReference

768414
stoichiometry: 1.0
species: 730148
type: SpeciesReference

037038
notes: R_H6ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6ET3er equation: [r] : m2emgacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H4ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ET3er equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + em3gacpail_hs R_M4CET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4CET3er equation: [r] : m3emgacpail_hs + pe_hs --> dag_hs + mem2emgacpail_hs
product: 813881
product: 813905
reversible: false
product: 813893
is: ENSCAFG00000002000.2
reactant: 813820
reactant: 813845
reactant: 813832
fast: false
type: Reaction
reactant: 813857
product: 813869

830373
stoichiometry: 1.0
species: 750514
type: SpeciesReference

036507
modifier: 809603
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal R_NTD11 subsystem: Purine Catabolism R_NTD11 equation: [c] : h2o + imp --> ins + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD7 subsystem: Nucleotides R_NTD7 equation: [c] : amp + h2o --> adn + pi
product: 809519
type: Reaction
modifier: 809639
modifier: 809591
modifier: 809567
reversible: false
product: 809495
reactant: 809459
modifier: 809627
fast: false
is: ENSCAFG00000003760.2
reactant: 809471
modifier: 809579
modifier: 809555
product: 809531
modifier: 809543
is: http://identifiers.org/ec-code/3.1.3.5
reactant: 809446
modifier: 809615
is: http://identifiers.org/ec-code/1.1.1.105
product: 809507
reactant: 809483

786617
stoichiometry: 1.0
species: 750598
type: SpeciesReference

839979
stoichiometry: 1.0
species: 747698
type: SpeciesReference

776903
stoichiometry: 1.0
species: 746303
type: SpeciesReference

818509
stoichiometry: 1.0
species: 740385
type: SpeciesReference

825772
stoichiometry: 1.0
species: 746074
type: SpeciesReference

791209
stoichiometry: 1.0
species: 741705
type: SpeciesReference

772701
stoichiometry: 1.0
species: 726488
type: SpeciesReference

743180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 15_C160H257N11O140S8
type: Species

750720
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: PA6_C90H145N6O65X
type: Species

742260
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 7_C67H99N4O80S8
type: Species

039527
product: 838728
name: transaldolase
fast: false
reversible: true
notes: R_TALA subsystem: Pentose Phosphate Pathway R_TALA equation: [c] : g3p + s7p <==> e4p + f6p
product: 838741
reactant: 838715
type: Reaction
is: http://identifiers.org/ec-code/2.2.1.2
is: ENSCAFG00000006594.2
reactant: 838702

788577
stoichiometry: 1.0
species: 750008
type: SpeciesReference

822189
stoichiometry: 2.0
species: 741283
type: SpeciesReference

802446
stoichiometry: 2.0
species: 731694
type: SpeciesReference

738147
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Formaldehyde_CH2O
type: Species

035804
product: 803073
reactant: 803061
notes: R_It subsystem: Transport, Extracellular R_It equation: i[e] <==> i[c]
is: ENSCAFG00000006942.1
fast: false
reversible: true
name: Iodide uniport
type: Reaction

819751
stoichiometry: 1.0
species: 744772
type: SpeciesReference

847008
stoichiometry: 17.0
species: 741296
type: SpeciesReference

799593
stoichiometry: 1.0
species: 750321
type: SpeciesReference

036748
reactant: 811360
product: 811566
product: 811456
reactant: 811420
reactant: 811336
reactant: 811312
reactant: 811396
product: 811494
product: 811530
product: 811481
product: 811542
product: 811518
product: 811506
product: 811578
reactant: 811348
reactant: 811324
product: 811432
is: ENSCAFG00000004201.2
reactant: 811372
product: 811468
type: Reaction
notes: R_ALAASNNaEx subsystem: Transport, Extracellular R_ALAASNNaEx equation: ala-L[e] + asn-L[c] + na1[e] --> ala-L[c] + asn-L[e] + na1[c] R_SERASNNaEx subsystem: Transport, Extracellular R_SERASNNaEx equation: asn-L[c] + na1[e] + ser-L[e] --> asn-L[e] + na1[c] + ser-L[c] R_GLNSERNaEx subsystem: Transport, Extracellular R_GLNSERNaEx equation: gln-L[e] + na1[e] + ser-L[c] --> gln-L[c] + na1[c] + ser-L[e] R_SERGLNNaEx subsystem: Transport, Extracellular R_SERGLNNaEx equation: gln-L[c] + na1[e] + ser-L[e] --> gln-L[e] + na1[c] + ser-L[c] R_CYSTHRNaEx subsystem: Transport, Extracellular R_CYSTHRNaEx equation: cys-L[e] + na1[e] + thr-L[c] --> cys-L[c] + na1[c] + thr-L[e] R_ASNGLNNaEx subsystem: Transport, Extracellular R_ASNGLNNaEx equation: asn-L[e] + gln-L[c] + na1[e] --> asn-L[c] + gln-L[e] + na1[c] R_GLNTHRNaEx subsystem: Transport, Extracellular R_GLNTHRNaEx equation: gln-L[e] + na1[e] + thr-L[c] --> gln-L[c] + na1[c] + thr-L[e] R_ASNTHRNaEx subsystem: Transport, Extracellular R_ASNTHRNaEx equation: asn-L[e] + na1[e] + thr-L[c] --> asn-L[c] + na1[c] + thr-L[e] R_THRSERNaEx subsystem: Transport, Extracellular R_THRSERNaEx equation: na1[e] + ser-L[c] + thr-L[e] --> na1[c] + ser-L[e] + thr-L[c] R_ALACYSNaEx subsystem: Transport, Extracellular R_ALACYSNaEx equation: ala-L[e] + cys-L[c] + na1[e] --> ala-L[c] + cys-L[e] + na1[c] R_GLNCYSNaEx subsystem: Transport, Extracellular R_GLNCYSNaEx equation: cys-L[c] + gln-L[e] + na1[e] --> cys-L[e] + gln-L[c] + na1[c] R_THRALANaEx subsystem: Transport, Extracellular R_THRALANaEx equation: ala-L[c] + na1[e] + thr-L[e] --> ala-L[e] + na1[c] + thr-L[c] R_GLNASNNaEx subsystem: Transport, Extracellular R_GLNASNNaEx equation: asn-L[c] + gln-L[e] + na1[e] --> asn-L[e] + gln-L[c] + na1[c] R_CYSALANaEx subsystem: Transport, Extracellular R_CYSALANaEx equation: ala-L[c] + cys-L[e] + na1[e] --> ala-L[e] + cys-L[c] + na1[c] R_CYSGLNNaEx subsystem: Transport, Extracellular R_CYSGLNNaEx equation: cys-L[e] + gln-L[c] + na1[e] --> cys-L[c] + gln-L[e]…
product: 811554
product: 811444
reactant: 811408
reversible: false
reactant: 811300
fast: false
reactant: 811276
reactant: 811288
reactant: 811384

821306
stoichiometry: 1.0
species: 737176
type: SpeciesReference

777445
stoichiometry: 1.0
species: 726924
type: SpeciesReference

777011
stoichiometry: 2.0
species: 747173
type: SpeciesReference

786509
stoichiometry: 1.0
species: 730124
type: SpeciesReference

827003
stoichiometry: 1.0
species: 746978
type: SpeciesReference

740862
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO
type: Species

802592
stoichiometry: 1.0
species: 744624
type: SpeciesReference

839293
stoichiometry: 1.0
species: 742115
type: SpeciesReference

751276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Sphinganine 1-phosphate_C18H39NO5P
type: Species

781934
stoichiometry: 1.0
species: 748387
type: SpeciesReference

844772
stoichiometry: 1.0
species: 730052
type: SpeciesReference

783003
stoichiometry: 2.0
species: 749249
type: SpeciesReference

852820
stoichiometry: 1.0
species: 739815
type: SpeciesReference

767460
stoichiometry: 1.0
species: 736971
type: SpeciesReference

730064
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Acetoacetate_C4H5O3
type: Species

812674
stoichiometry: 1.0
species: 727588
type: SpeciesReference

750008
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin E2_C20H31O5
type: Species

728137
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Hydroxyphenylacetate_C8H7O3
type: Species

833182
stoichiometry: 2.0
species: 746617
type: SpeciesReference

034878
is: ENSCAFG00000020089.2
is: http://identifiers.org/ec-code/5.3.99.3
fast: false
reactant: 793834
reversible: true
is: ENSCAFG00000012528.2
type: Reaction
notes: R_PGESr subsystem: Eicosanoid Metabolism R_PGESr equation: [r] : prostgh2 <==> prostge2
name: Prostaglandin E synthase
product: 793846

757163
stoichiometry: 1.0
species: 731127
type: SpeciesReference

801427
stoichiometry: 1.0
species: 727528
type: SpeciesReference

837098
stoichiometry: 30.0
species: 747099
type: SpeciesReference

808902
stoichiometry: 1.0
species: 746774
type: SpeciesReference

826579
stoichiometry: 1.0
species: 753230
type: SpeciesReference

757735
stoichiometry: 2.0
species: 746978
type: SpeciesReference

803339
stoichiometry: 1.0
species: 751446
type: SpeciesReference

849140
stoichiometry: 1.0
species: 741356
type: SpeciesReference

742696
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: L-Iduronate_C6H9O7
type: Species

796272
stoichiometry: 3.0
species: 738051
type: SpeciesReference

762434
stoichiometry: 1.0
species: 733555
type: SpeciesReference

789952
stoichiometry: 3.0
species: 732441
type: SpeciesReference

836110
stoichiometry: 1.0
species: 752878
type: SpeciesReference

819172
stoichiometry: 1.0
species: 740530
type: SpeciesReference

782775
stoichiometry: 2.0
species: 741332
type: SpeciesReference

756248
stoichiometry: 1.0
species: 733606
type: SpeciesReference

826748
stoichiometry: 1.0
species: 747074
type: SpeciesReference

760908
stoichiometry: 1.0
species: 737642
type: SpeciesReference

752777
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Trehalose_C12H22O11
type: Species

749779
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pristanal_C19H38O
type: Species

040055
reversible: false
notes: R_PIK4 subsystem: Glycerophospholipid Metabolism R_PIK4 equation: [c] : atp + pail_hs --> adp + h + pail4p_hs R_PI3P4K subsystem: Inositol Phosphate Metabolism R_PI3P4K equation: [c] : atp + pail3p_hs --> adp + h + pail34p_hs R_PI5P4K subsystem: Inositol Phosphate Metabolism R_PI5P4K equation: [c] : atp + pail5p_hs --> adp + h + pail45p_hs
product: 842828
is: ENSCAFG00000009222.2
product: 842840
is: http://identifiers.org/ec-code/2.7.1.149
reactant: 842763
is: http://identifiers.org/ec-code/2.7.1.67
type: Reaction
product: 842815
product: 842789
reactant: 842737
is: ENSCAFG00000012633.2
reactant: 842750
reactant: 842776
product: 842802
fast: false

816584
stoichiometry: 1.0
species: 741464
type: SpeciesReference

746267
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Mesaconyl-CoA_C26H35N7O19P3S
type: Species

781240
stoichiometry: 8.0
species: 733750
type: SpeciesReference

040621
product: 850490
is: ENSCAFG00000025532.1
product: 850502
fast: false
product: 850526
reactant: 850430
reactant: 850454
reactant: 850442
type: Reaction
reactant: 850466
product: 850514
reactant: 850406
reactant: 850418
notes: R_NTD5 subsystem: Pyrimidine Catabolism R_NTD5 equation: [c] : dtmp + h2o --> pi + thymd R_NTD1 subsystem: Pyrimidine Catabolism R_NTD1 equation: [c] : dump + h2o --> duri + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD8 subsystem: Nucleotides R_NTD8 equation: [c] : dgmp + h2o --> dgsn + pi R_NTD12 subsystem: Nucleotides R_NTD12 equation: [c] : dimp + h2o --> din + pi
product: 850478
product: 850538
reversible: false
is: http://identifiers.org/ec-code/3.1.3.5

730922
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ADP_C10H12N5O10P2
type: Species

739668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: GDP_C10H12N5O11P2
type: Species

824966
stoichiometry: 1.0
species: 729750
type: SpeciesReference

788012
stoichiometry: 3.0
species: 731755
type: SpeciesReference

787856
stoichiometry: 1.0
species: 753762
type: SpeciesReference

758544
stoichiometry: 3.0
species: 741259
type: SpeciesReference

039152
fast: false
reactant: 835027
notes: R_UGALNACter subsystem: Transport, Endoplasmic Reticular R_UGALNACter equation: udpacgal[c] + ump[r] <==> udpacgal[r] + ump[c] R_UDPGLCAter subsystem: Transport, Endoplasmic Reticular R_UDPGLCAter equation: udpglcur[r] + ump[c] <==> udpglcur[c] + ump[r]
product: 835051
reactant: 835003
product: 835039
product: 835075
type: Reaction
is: ENSCAFG00000018543.2
product: 835063
reactant: 834991
reversible: true
reactant: 835015

849586
stoichiometry: 1.0
species: 737326
type: SpeciesReference

785175
stoichiometry: 1.0
species: 734646
type: SpeciesReference

814564
stoichiometry: 1.0
species: 750369
type: SpeciesReference

760382
stoichiometry: 1.0
species: 730922
type: SpeciesReference

827413
stoichiometry: 1.0
species: 746521
type: SpeciesReference

789095
stoichiometry: 1.0
species: 753664
type: SpeciesReference

738438
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Farnesyl diphosphate_C15H25O7P2
type: Species

812529
stoichiometry: 3.0
species: 743072
type: SpeciesReference

841893
stoichiometry: 1.0
species: 732032
type: SpeciesReference

772159
stoichiometry: 1.0
species: 744314
type: SpeciesReference

731718
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: S-Adenosyl-L-methionine_C15H23N6O5S
type: Species

779447
stoichiometry: 2.0
species: 731429
type: SpeciesReference

041142
product: 855002
type: Reaction
fast: false
notes: R_ST6GALNAC26 subsystem: Sphingolipid Metabolism R_ST6GALNAC26 equation: [g] : cmpacna + gt1alpha_hs --> cmp + gq1balpha_hs + h R_ST6GALNAC25 subsystem: Sphingolipid Metabolism R_ST6GALNAC25 equation: [g] : cmpacna + gd1alpha_hs --> cmp + gt1alpha_hs + h R_ST6GALNAC24 subsystem: Sphingolipid Metabolism R_ST6GALNAC24 equation: [g] : cmpacna + gm1a_hs --> cmp + gd1b2_hs + h R_ST6GALNAC22 subsystem: Sphingolipid Metabolism R_ST6GALNAC22 equation: [g] : acngalgbside_hs + cmpacna --> acn23acngalgbside_hs + cmp + h R_ST6GALNAC21 subsystem: Sphingolipid Metabolism R_ST6GALNAC21 equation: [g] : acngalgbside_hs + cmpacna --> acn13acngalgbside_hs + cmp + h R_ST6GALNAC27 subsystem: Sphingolipid Metabolism R_ST6GALNAC27 equation: [g] : cmpacna + gt1c_hs --> cmp + gq1c_hs + h R_ST6GALNAC23 subsystem: Sphingolipid Metabolism R_ST6GALNAC23 equation: [g] : cmpacna + ga2_hs --> cmp + gm2a_hs + h R_ST6GALNAC28 subsystem: Sphingolipid Metabolism R_ST6GALNAC28 equation: [g] : cmpacna + gq1c_hs --> cmp + gp1c_hs + h
reactant: 854893
product: 855098
reactant: 854917
product: 855086
reactant: 854953
product: 855074
reactant: 854929
product: 855038
reversible: false
reactant: 854978
product: 854990
reactant: 854965
product: 855062
product: 855026
product: 855050
reactant: 854905
product: 855014
reactant: 854941
is: ENSCAFG00000005122.2

729610
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total 3 Coenzyme A_CO2FULLR3C21H31N7O15P3S
type: Species

743300
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 23_C124H201N8O106S5
type: Species

753254
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
type: Species

851593
stoichiometry: 1.0
species: 747099
type: SpeciesReference

783220
stoichiometry: 1.0
species: 750068
type: SpeciesReference

774017
stoichiometry: 1.0
species: 746098
type: SpeciesReference

831474
stoichiometry: 1.0
species: 739607
type: SpeciesReference

814456
stoichiometry: 1.0
species: 741151
type: SpeciesReference

741308
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: H+_H
type: Species

031343
product: 762603
is: http://identifiers.org/ec-code/5.1.3.14
reactant: 762555
notes: R_UAG2EMAi subsystem: Aminosugar Metabolism R_UAG2EMAi equation: [c] : h2o + uacgam --> acmana + h + udp R_AMANK subsystem: Aminosugar Metabolism R_AMANK equation: [c] : acmana + atp --> acmanap + adp + h
reactant: 762543
reversible: false
is: ENSCAFG00000002304.2
is: http://identifiers.org/ec-code/2.7.1.60
reactant: 762531
product: 762591
product: 762567
fast: false
product: 762615
product: 762579
reactant: 762519
type: Reaction

783873
stoichiometry: 4.0
species: 739827
type: SpeciesReference

846330
stoichiometry: 1.0
species: 741259
type: SpeciesReference

854303
stoichiometry: 1.0
species: 727118
type: SpeciesReference

754838
stoichiometry: 1.0
species: 748959
type: SpeciesReference

033620
reversible: false
product: 782727
product: 782751
fast: false
product: 782775
reactant: 782679
reactant: 782703
product: 782739
type: Reaction
is: ENSCAFG00000004822.2
reactant: 782715
notes: R_DOLPGT2_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT2_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g1m8mpdol_L --> (0.1) dolp_L + (0.1) g2m8mpdol_L + h R_DOLPGT2_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT2_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g1m8mpdol_U --> (0.1) dolp_U + (0.1) g2m8mpdol_U + h
product: 782763
reactant: 782691

852748
stoichiometry: 1.0
species: 741187
type: SpeciesReference

807423
stoichiometry: 1.0
species: 744676
type: SpeciesReference

831884
stoichiometry: 1.0
species: 752253
type: SpeciesReference

783668
stoichiometry: 1.0
species: 753350
type: SpeciesReference

797301
stoichiometry: 1.0
species: 743745
type: SpeciesReference

782751
stoichiometry: 1.0
species: 738943
type: SpeciesReference

805261
stoichiometry: 5.0
species: 749200
type: SpeciesReference

767678
stoichiometry: 1.0
species: 747002
type: SpeciesReference

734501
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 3_C45H67N2O42S2X
type: Species

835437
stoichiometry: 13.0
species: 753314
type: SpeciesReference

763816
stoichiometry: 2.0
species: 741259
type: SpeciesReference

761537
stoichiometry: 1.0
species: 753579
type: SpeciesReference

753894
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Xanthosine 5'-phosphate_C10H11N4O9P
type: Species

819064
stoichiometry: 1.0
species: 741235
type: SpeciesReference

834337
stoichiometry: 1.0
species: 731465
type: SpeciesReference

774169
stoichiometry: 1.0
species: 740481
type: SpeciesReference

032426
reactant: 772919
fast: false
product: 772955
is: ENSCAFG00000012416.2
reactant: 772931
product: 772991
notes: R_CTPS2 subsystem: Pyrimidine Biosynthesis R_CTPS2 equation: [c] : atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi
type: Reaction
reactant: 772907
product: 773003
name: CTP synthase (glutamine)
reversible: false
product: 772967
reactant: 772943
is: http://identifiers.org/ec-code/6.3.4.2
product: 772979

855581
stoichiometry: 4.0
species: 741259
type: SpeciesReference

798066
stoichiometry: 1.0
species: 745085
type: SpeciesReference

758267
stoichiometry: 1.0
species: 750393
type: SpeciesReference

784707
stoichiometry: 1.0
species: 746388
type: SpeciesReference

832532
stoichiometry: 2.0
species: 741271
type: SpeciesReference

838909
stoichiometry: 1.0
species: 735276
type: SpeciesReference

031753
notes: R_ASP1DC subsystem: beta-Alanine metabolism R_ASP1DC equation: [c] : asp-L + h --> ala-B + co2 R_3SALACBOXL subsystem: Taurine and hypotaurine metabolism R_3SALACBOXL equation: [c] : 3sala + h --> co2 + hyptaur R_GLUDC subsystem: Glutamate metabolism R_GLUDC equation: [c] : glu-L + h --> 4abut + co2 R_LCYSTCBOXL subsystem: Taurine and hypotaurine metabolism R_LCYSTCBOXL equation: [c] : Lcyst + h --> co2 + taur
reactant: 766485
is: http://identifiers.org/ec-code/4.1.1.15
reactant: 766497
fast: false
product: 766570
reactant: 766509
product: 766594
is: ENSCAFG00000012560.2
reactant: 766534
reactant: 766521
product: 766546
type: Reaction
is: ENSCAFG00000000089.2
product: 766582
product: 766558
is: http://identifiers.org/ec-code/4.1.1.11
reversible: false

754404
stoichiometry: 1.0
species: 738171
type: SpeciesReference

838049
stoichiometry: 1.0
species: 750683
type: SpeciesReference

757856
stoichiometry: 1.0
species: 730391
type: SpeciesReference

763113
stoichiometry: 1.0
species: 741259
type: SpeciesReference

744820
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Leukotriene A4_C20H29O3
type: Species

732164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: arachidonic acid_C20H31O2
type: Species

800642
stoichiometry: 2.0
species: 746930
type: SpeciesReference

759171
stoichiometry: 3.0
species: 747074
type: SpeciesReference

803968
stoichiometry: 1.5
species: 746930
type: SpeciesReference

034071
is: ENSCAFG00000009243.2
product: 786148
product: 786040
reactant: 785963
type: Reaction
notes: R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_ARGtiDF subsystem: Transport, Extracellular R_ARGtiDF equation: arg-L[e] --> arg-L[c] R_LYStiDF subsystem: Transport, Extracellular R_LYStiDF equation: lys-L[e] --> lys-L[c] R_HIStiDF subsystem: Transport, Extracellular R_HIStiDF equation: his-L[e] --> his-L[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
reactant: 785888
reversible: false
reactant: 785925
reactant: 786015
product: 786172
product: 786124
product: 786100
product: 786076
product: 786052
reactant: 786002
reactant: 785937
reactant: 785912
reactant: 786028
reactant: 785989
reactant: 785976
product: 786136
product: 786112
product: 786088
product: 786064
fast: false
reactant: 785950
reactant: 785900
product: 786160

853674
stoichiometry: 2.0
species: 746978
type: SpeciesReference

782186
stoichiometry: 1.0
species: 745375
type: SpeciesReference

768987
stoichiometry: 1.0
species: 739438
type: SpeciesReference

829157
stoichiometry: 1.0
species: 743072
type: SpeciesReference

033088
name: phosphate transport in/out via two Na+ symporter
type: Reaction
product: 778445
is: ENSCAFG00000019464.2
product: 778458
fast: false
notes: R_PIt9 subsystem: Transport, Extracellular R_PIt9 equation: (2) na1[e] + pi[e] <==> (2) na1[c] + pi[c]
reactant: 778433
reversible: true
reactant: 778421

810423
stoichiometry: 1.0
species: 751796
type: SpeciesReference

786220
stoichiometry: 2.0
species: 747758
type: SpeciesReference

751953
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)_C25H45N2O8PRS
type: Species

754123
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane_C27H48O4
type: Species

768831
stoichiometry: 1.0
species: 739692
type: SpeciesReference

739559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO
type: Species

764202
stoichiometry: 1.0
species: 741151
type: SpeciesReference

746158
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol-Protein (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2X
type: Species

768770
stoichiometry: 1.0
species: 739147
type: SpeciesReference

853085
stoichiometry: 1.0
species: 747148
type: SpeciesReference

837520
stoichiometry: 1.0
species: 749442
type: SpeciesReference

798836
stoichiometry: 5.0
species: 735950
type: SpeciesReference

836002
stoichiometry: 1.0
species: 740530
type: SpeciesReference

825628
stoichiometry: 2.0
species: 731755
type: SpeciesReference

782294
stoichiometry: 1.0
species: 736207
type: SpeciesReference

732961
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: cervonyl carnitine_C29H45NO4
type: Species

769397
stoichiometry: 1.0
species: 741151
type: SpeciesReference

794006
stoichiometry: 2.0
species: 747123
type: SpeciesReference

788120
stoichiometry: 1.0
species: 733165
type: SpeciesReference

778614
stoichiometry: 1.0
species: 740639
type: SpeciesReference

785584
stoichiometry: 1.0
species: 739926
type: SpeciesReference

778071
stoichiometry: 1.0
species: 753387
type: SpeciesReference

787748
stoichiometry: 1.0
species: 737714
type: SpeciesReference

797758
stoichiometry: 1.0
species: 748085
type: SpeciesReference

033790
product: 783764
notes: R_GTMLTe subsystem: Glutathione Metabolism R_GTMLTe equation: ala-L[c] + gthrd[c] --> cgly[e] + gluala[e]
reversible: false
is: http://identifiers.org/ec-code/2.3.2.2
name: g-glutamyltransferase (e)
reactant: 783752
type: Reaction
is: ENSCAFG00000013899.2
fast: false
product: 783776
reactant: 783740

780169
stoichiometry: 1.0
species: 732817
type: SpeciesReference

761756
stoichiometry: 1.0
species: 732188
type: SpeciesReference

783111
stoichiometry: 1.0
species: 744637
type: SpeciesReference

843178
stoichiometry: 1.0
species: 739939
type: SpeciesReference

809676
stoichiometry: 2.0
species: 747698
type: SpeciesReference

771022
stoichiometry: 12.0
species: 741259
type: SpeciesReference

852520
stoichiometry: 2.0
species: 754111
type: SpeciesReference

779712
stoichiometry: 1.0
species: 748206
type: SpeciesReference

772268
stoichiometry: 1.0
species: 743853
type: SpeciesReference

807531
stoichiometry: 1.0
species: 740241
type: SpeciesReference

755936
stoichiometry: 1.0
species: 741199
type: SpeciesReference

809775
stoichiometry: 1.0
species: 748934
type: SpeciesReference

745507
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21
type: Species

809230
stoichiometry: 1.0
species: 739901
type: SpeciesReference

799653
stoichiometry: 1.0
species: 750285
type: SpeciesReference

792184
stoichiometry: 1.0
species: 742491
type: SpeciesReference

824819
stoichiometry: 1.0
species: 745266
type: SpeciesReference

827522
stoichiometry: 1.0
species: 735204
type: SpeciesReference

838626
stoichiometry: 1.0
species: 740217
type: SpeciesReference

031065
modifier: 760322
reactant: 760138
modifier: 760248
is: ENSCAFG00000004928.2
is: ENSCAFG00000009239.2
modifier: 760285
is: ENSCAFG00000002071.2
product: 760236
product: 760211
reactant: 760175
reactant: 760151
type: Reaction
reactant: 760126
modifier: 760260
is: ENSCAFG00000012195.2
modifier: 760309
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
is: http://identifiers.org/ec-code/1.1.1.27
reactant: 760163
modifier: 760297
modifier: 760334
product: 760187
reactant: 760114
fast: false
reversible: false
modifier: 760273
product: 760199
is: http://identifiers.org/ec-code/1.2.3.5
is: ENSCAFG00000006066.2
product: 760224
modifier: 760346

742479
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 9_C87H129N5O69X
type: Species

763707
stoichiometry: 1.0
species: 740445
type: SpeciesReference

829265
stoichiometry: 1.0
species: 754135
type: SpeciesReference

733786
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: clupanodonyl CoA_C43H64N7O17P3S
type: Species

736728
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dimethylallyl diphosphate_C5H9O7P2
type: Species

812397
stoichiometry: 1.0
species: 744700
type: SpeciesReference

744976
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

781821
stoichiometry: 1.0
species: 738546
type: SpeciesReference

726149
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19
type: Species

792883
stoichiometry: 1.0
species: 729858
type: SpeciesReference

846754
stoichiometry: 1.0
species: 744157
type: SpeciesReference

732272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Arginine_C6H15N4O2
type: Species

842302
stoichiometry: 2.0
species: 741175
type: SpeciesReference

776600
stoichiometry: 1.0
species: 734018
type: SpeciesReference

851376
stoichiometry: 1.0
species: 741151
type: SpeciesReference

790450
stoichiometry: 1.0
species: 736086
type: SpeciesReference

756020
stoichiometry: 1.0
species: 751288
type: SpeciesReference

031861
product: 767376
product: 767327
reactant: 767291
notes: R_HEX10 subsystem: Aminosugar Metabolism R_HEX10 equation: [c] : atp + gam --> adp + gam6p + h R_HEX4 subsystem: Fructose and Mannose Metabolism R_HEX4 equation: [c] : atp + man --> adp + h + man6p R_HEX7 subsystem: Fructose and Mannose Metabolism R_HEX7 equation: [c] : atp + fru --> adp + f6p + h R_HEX1 subsystem: Glycolysis/Gluconeogenesis R_HEX1 equation: [c] : atp + glc-D --> adp + g6p + h
product: 767364
product: 767351
is: ENSCAFG00000002944.2
reactant: 767315
product: 767388
reactant: 767267
is: ENSCAFG00000008265.2
reactant: 767279
is: http://identifiers.org/ec-code/2.7.1.7
is: http://identifiers.org/ec-code/2.7.1.1
reactant: 767303
is: ENSCAFG00000016584.2
type: Reaction
fast: false
reversible: false
is: ENSCAFG00000013917.2
product: 767339

783559
stoichiometry: 2.0
species: 731429
type: SpeciesReference

829902
stoichiometry: 1.0
species: 740180
type: SpeciesReference

848065
stoichiometry: 1.0
species: 731127
type: SpeciesReference

750574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _9-cis-retinol_C20H30O
type: Species

039262
product: 836592
fast: false
reversible: true
product: 836556
type: Reaction
is: http://identifiers.org/ec-code/2.6.1.42
product: 836580
product: 836568
reactant: 836520
reactant: 836508
reactant: 836544
reactant: 836532
is: ENSCAFG00000011487.2
notes: R_ILETA subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETA equation: [c] : akg + ile-L <==> 3mop + glu-L R_VALTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTA equation: [c] : akg + val-L <==> 3mob + glu-L R_LEUTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTA equation: [c] : akg + leu-L <==> 4mop + glu-L
is: http://identifiers.org/ec-code/2.6.1.6

853783
stoichiometry: 2.0
species: 741187
type: SpeciesReference

034180
product: 787699
is: ENSCAFG00000005028.2
type: Reaction
reactant: 787650
fast: false
name: xylulokinase
reversible: false
is: http://identifiers.org/ec-code/2.7.1.17
reactant: 787662
product: 787674
product: 787687
notes: R_XYLK subsystem: Pentose and Glucuronate Interconversions R_XYLK equation: [c] : atp + xylu-D --> adp + h + xu5p-D

806027
stoichiometry: 1.0
species: 732356
type: SpeciesReference

778722
stoichiometry: 1.0
species: 740409
type: SpeciesReference

817138
stoichiometry: 1.0
species: 753991
type: SpeciesReference

830096
stoichiometry: 1.0
species: 736535
type: SpeciesReference

031499
product: 763960
reactant: 763912
is: http://identifiers.org/ec-code/3.2.1.96
is: ENSCAFG00000005545.2
fast: false
reversible: false
reactant: 763924
reactant: 763900
product: 763936
product: 763948
notes: R_ENGASE2 subsystem: N-Glycan Degradation R_ENGASE2 equation: [c] : h2o + n2m2nm --> acgam + n2m2nmn R_ENGASE subsystem: N-Glycan Degradation R_ENGASE equation: [c] : h2o + s2l2n2m2m --> acgam + s2l2n2m2mn
type: Reaction

754946
stoichiometry: 1.0
species: 727955
type: SpeciesReference

757965
stoichiometry: 2.0
species: 743000
type: SpeciesReference

748399
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2
type: Species

773219
stoichiometry: 1.0
species: 741259
type: SpeciesReference

749550
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6
type: Species

757416
stoichiometry: 1.0
species: 732212
type: SpeciesReference

031126
product: 760770
reactant: 760732
is: ENSCAFG00000015338.2
is: http://identifiers.org/ec-code/1.14.14.1
notes: R_P45019A2r subsystem: Steroid Metabolism R_P45019A2r equation: [r] : nadph + (2) o2 + tststerone --> estradiol + for + (2) h2o + nadp R_P45019A1r subsystem: Steroid Metabolism R_P45019A1r equation: [r] : andrstndn + nadph + (2) o2 --> estrone + for + (2) h2o + nadp
reactant: 760744
reactant: 760708
fast: false
product: 760796
reversible: false
product: 760810
product: 760757
reactant: 760720
type: Reaction
product: 760783

749996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Prostaglandin E1_C20H33O5
type: Species

826856
stoichiometry: 3.0
species: 741271
type: SpeciesReference

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stoichiometry: 2.0
species: 747062
type: SpeciesReference

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stoichiometry: 2.0
species: 749200
type: SpeciesReference

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stoichiometry: 32.0
species: 747038
type: SpeciesReference

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stoichiometry: 1.0
species: 731960
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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type: Species

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stoichiometry: 1.0
species: 732441
type: SpeciesReference

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stoichiometry: 9.0
species: 735938
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: naphthalene epoxide_C10H8O
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Sarcosine_C3H7NO2
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ethanolamine_C2H8NO
type: Species

771335
stoichiometry: 1.0
species: 745940
type: SpeciesReference

773957
stoichiometry: 2.0
species: 741283
type: SpeciesReference

835942
stoichiometry: 1.0
species: 743769
type: SpeciesReference

807748
stoichiometry: 1.0
species: 747050
type: SpeciesReference

756484
stoichiometry: 1.0
species: 737690
type: SpeciesReference

817402
stoichiometry: 1.0
species: 726766
type: SpeciesReference

764637
stoichiometry: 1.0
species: 730922
type: SpeciesReference

742164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 23_C31H49NO29S
type: Species

784815
stoichiometry: 1.0
species: 742479
type: SpeciesReference

039418
product: 838025
reversible: false
reactant: 837988
fast: false
type: Reaction
reactant: 837976
product: 838013
is: ENSCAFG00000014054.2
product: 838000
is: http://identifiers.org/ec-code/3.1.1.7
name: Acetylcholinesterase
notes: R_ACHEe subsystem: Glycerophospholipid Metabolism R_ACHEe equation: [e] : ach + h2o --> ac + chol + h

731585
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Alanine_C3H7NO2
type: Species

823574
stoichiometry: 10.0
species: 753194
type: SpeciesReference

831727
stoichiometry: 1.0
species: 736111
type: SpeciesReference

038646
reactant: 830596
reactant: 830583
reversible: false
is: http://identifiers.org/ec-code/2.1.2.5
product: 830669
product: 830633
product: 830645
notes: R_GluForTx subsystem: Histidine Metabolism R_GluForTx equation: [c] : forglu + h + thf --> 5forthf + glu-L R_FTCD subsystem: Folate Metabolism R_FTCD equation: [c] : 5forthf + (2) h --> methf + nh4
reactant: 830621
product: 830657
is: http://identifiers.org/ec-code/4.3.1.4
fast: false
reactant: 830609
is: ENSCAFG00000011926.2
type: Reaction

850610
stoichiometry: 8.0
species: 741259
type: SpeciesReference

790678
stoichiometry: 1.0
species: 735155
type: SpeciesReference

034577
product: 791738
notes: R_GTHO subsystem: Glutamate metabolism R_GTHO equation: [c] : gthox + h + nadph --> (2) gthrd + nadp R_GTHOm subsystem: Glutamate metabolism R_GTHOm equation: [m] : gthox + h + nadph --> (2) gthrd + nadp
type: Reaction
fast: false
reactant: 791678
is: http://identifiers.org/ec-code/1.8.1.7
product: 791726
product: 791714
is: ENSCAFG00000004386.2
reversible: false
reactant: 791666
reactant: 791642
reactant: 791654
reactant: 791630
reactant: 791690
product: 791702

841473
stoichiometry: 1.0
species: 747123
type: SpeciesReference

777555
stoichiometry: 1.0
species: 741223
type: SpeciesReference

842840
stoichiometry: 3.0
species: 741259
type: SpeciesReference

032727
is: ENSCAFG00000007507.2
reactant: 775691
fast: false
product: 775727
product: 775703
notes: R_A4GNT1g subsystem: O-Glycan Biosynthesis R_A4GNT1g equation: [g] : T_antigen + uacgam --> gncore1 + h + udp R_A4GNT2g subsystem: O-Glycan Biosynthesis R_A4GNT2g equation: [g] : core2 + uacgam --> gncore2 + h + udp
reactant: 775679
type: Reaction
reactant: 775667
product: 775715
reversible: false
product: 775739

822827
stoichiometry: 1.0
species: 741308
type: SpeciesReference

813084
stoichiometry: 1.0
species: 749249
type: SpeciesReference

846088
stoichiometry: 18.0
species: 741308
type: SpeciesReference

751675
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Succinate_C4H4O4
type: Species

797457
stoichiometry: 1.0
species: 744338
type: SpeciesReference

849356
stoichiometry: 2.0
species: 743264
type: SpeciesReference

772412
stoichiometry: 1.0
species: 744265
type: SpeciesReference

808085
stoichiometry: 4.0
species: 741428
type: SpeciesReference

828748
stoichiometry: 1.0
species: 739510
type: SpeciesReference

844881
stoichiometry: 1.0
species: 744637
type: SpeciesReference

033949
is: ENSCAFG00000003077.2
product: 785259
reactant: 785247
product: 785271
reversible: false
name: gamma-glutamylcyclotransferase
notes: R_GGLUCT subsystem: Glutathione Metabolism R_GGLUCT equation: gluala[e] --> 5oxpro[c] + ala-L[c]
fast: false
is: http://identifiers.org/ec-code/2.3.2.4
type: Reaction

772859
stoichiometry: 1.0
species: 733009
type: SpeciesReference

788421
stoichiometry: 1.0
species: 741187
type: SpeciesReference

843395
stoichiometry: 3.0
species: 740675
type: SpeciesReference

727251
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: D-3-Amino-isobutanoate_C4H9NO2
type: Species

727516
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxykynurenamine_C9H13N2O2
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728028
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _4-Aminobutanal_C4H10NO
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819280
stoichiometry: 7.0
species: 739815
type: SpeciesReference

758763
stoichiometry: 1.0
species: 741308
type: SpeciesReference

755502
stoichiometry: 2.0
species: 751820
type: SpeciesReference

811144
stoichiometry: 1.0
species: 741283
type: SpeciesReference

751385
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Sphingosine 1-phosphate_C18H37NO5P
type: Species

796164
stoichiometry: 1.0
species: 744484
type: SpeciesReference

813192
stoichiometry: 1.0
species: 741332
type: SpeciesReference

760090
stoichiometry: 3.0
species: 749200
type: SpeciesReference

748821
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: propionyl-carnitine_C10H19NO4
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036857
product: 812203
fast: false
product: 812215
type: Reaction
is: ENSCAFG00000019878.2
notes: R_DPMVDx subsystem: Cholesterol Metabolism R_DPMVDx equation: [x] : 5dpmev + atp --> adp + co2 + ipdp + pi
reactant: 812179
reversible: false
name: diphosphomevalonate decarboxylase
product: 812227
is: http://identifiers.org/ec-code/4.1.1.33
product: 812239
reactant: 812191

792595
stoichiometry: 1.0
species: 734091
type: SpeciesReference

745627
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1545H2540N20O470P20
type: Species

777120
stoichiometry: 1.0
species: 752790
type: SpeciesReference

739280
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)6 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C96H165N4O60FULLRCO
type: Species

760151
stoichiometry: 1.0
species: 740132
type: SpeciesReference

737630
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
type: Species

734187
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Core 6_C16H27N2O10X
type: Species

772304
stoichiometry: 1.0
species: 743890
type: SpeciesReference

847117
stoichiometry: 1.0
species: 744169
type: SpeciesReference

806917
stoichiometry: 2.0
species: 747782
type: SpeciesReference

806785
stoichiometry: 1.0
species: 747173
type: SpeciesReference

766509
stoichiometry: 1.0
species: 739987
type: SpeciesReference

762325
stoichiometry: 1.0
species: 736291
type: SpeciesReference

780988
stoichiometry: 1.0
species: 732501
type: SpeciesReference

830645
stoichiometry: 1.0
species: 746315
type: SpeciesReference

851165
stoichiometry: 1.0
species: 750429
type: SpeciesReference

844217
stoichiometry: 1.0
species: 726440
type: SpeciesReference

797530
stoichiometry: 3.0
species: 738087
type: SpeciesReference

788361
stoichiometry: 1.0
species: 738075
type: SpeciesReference

853254
stoichiometry: 1.0
species: 732841
type: SpeciesReference

822610
stoichiometry: 1.0
species: 736922
type: SpeciesReference

826145
stoichiometry: 1.0
species: 736947
type: SpeciesReference

035457
name: inositol transport via sodium symport
reactant: 800654
notes: R_INSTt4_2 subsystem: Transport, Extracellular R_INSTt4_2 equation: inost[e] + (2) na1[e] <==> inost[c] + (2) na1[c]
reversible: true
type: Reaction
product: 800678
reactant: 800642
fast: false
is: ENSCAFG00000013498.2
is: ENSCAFG00000017501.2
is: ENSCAFG00000018237.2
product: 800666

037484
product: 819003
notes: R_3HBCDm subsystem: Butanoate Metabolism R_3HBCDm equation: [m] : b2coa + h2o <==> 3hbcoa-R
reactant: 818991
name: _3-hydroxybutyryl-CoA dehydratase, mitochondrial
reactant: 818979
is: http://identifiers.org/ec-code/4.2.1.55
is: ENSCAFG00000023378.1
reversible: true
fast: false
type: Reaction

793126
stoichiometry: 1.0
species: 745675
type: SpeciesReference

757626
stoichiometry: 2.0
species: 728257
type: SpeciesReference

737350
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Deoxyuridine_C9H12N2O5
type: Species

777228
stoichiometry: 1.0
species: 751082
type: SpeciesReference

798486
stoichiometry: 1.0
species: 745170
type: SpeciesReference

801318
stoichiometry: 1.0
species: 729919
type: SpeciesReference

768525
stoichiometry: 1.0
species: 751202
type: SpeciesReference

810868
stoichiometry: 1.0
species: 753338
type: SpeciesReference

034721
reactant: 792571
name: Hydroxymethylglutaryl CoA synthase (ir)
product: 792619
fast: false
reactant: 792559
notes: R_HMGCOASim subsystem: Cholesterol Metabolism R_HMGCOASim equation: [m] : aacoa + accoa + h2o --> coa + h + hmgcoa
product: 792595
type: Reaction
reactant: 792583
is: ENSCAFG00000010096.2
product: 792607
is: http://identifiers.org/ec-code/4.1.3.5
reversible: false

785367
stoichiometry: 1.0
species: 751082
type: SpeciesReference

798282
stoichiometry: 1.0
species: 752679
type: SpeciesReference

781505
stoichiometry: 3.0
species: 741151
type: SpeciesReference

828302
stoichiometry: 1.0
species: 753314
type: SpeciesReference

752205
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Tetracosatetraenoyl carnitine_C31H53NO4
type: Species

818389
stoichiometry: 1.0
species: 741802
type: SpeciesReference

738882
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C76H127N2O60X
type: Species

827377
stoichiometry: 3.0
species: 741151
type: SpeciesReference

734828
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 6_C23H35O27S2
type: Species

852977
stoichiometry: 1.0
species: 741259
type: SpeciesReference

827954
stoichiometry: 4.0
species: 749213
type: SpeciesReference

732525
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Crotonoyl-CoA_C25H36N7O17P3S
type: Species

781662
stoichiometry: 1.0
species: 733262
type: SpeciesReference

784503
stoichiometry: 3.0
species: 731176
type: SpeciesReference

742807
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Imidazole-4-acetate_C5H5N2O2
type: Species

850093
stoichiometry: 1.0
species: 744598
type: SpeciesReference

737091
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
type: Species

812962
stoichiometry: 1.0
species: 748375
type: SpeciesReference

761974
stoichiometry: 6.0
species: 741271
type: SpeciesReference

740481
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GM1b (homo sapiens)_C55H95N3O30FULLRCO
type: Species

820064
stoichiometry: 1.0
species: 743432
type: SpeciesReference

729501
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: R group 2 Coenzyme A homo sapiens_XCO2C21H31N7O15P3S
type: Species

828182
stoichiometry: 1.0
species: 728402
type: SpeciesReference

829482
stoichiometry: 1.0
species: 730922
type: SpeciesReference

799064
stoichiometry: 1.0
species: 731779
type: SpeciesReference

769179
stoichiometry: 1.0
species: 743072
type: SpeciesReference

747430
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C42H70N3O30X
type: Species

741814
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
type: Species

743612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 9_C188H301N13O166S10
type: Species

736886
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dolichyl phosphate D-mannose, human liver homolog_C1140H1868O90P10
type: Species

832424
stoichiometry: 1.0
species: 746870
type: SpeciesReference

823056
stoichiometry: 1.0
species: 747379
type: SpeciesReference

777779
stoichiometry: 1.0
species: 738510
type: SpeciesReference

803784
stoichiometry: 1.0
species: 741271
type: SpeciesReference

746376
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Methylhistamine_C6H12N3
type: Species

764070
stoichiometry: 1.0
species: 740825
type: SpeciesReference

804478
stoichiometry: 1.0
species: 749334
type: SpeciesReference

753725
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Vaccenyl carnitine_C25H47NO4
type: Species

033499
product: 781873
notes: R_F1PGT subsystem: Fructose and Mannose Metabolism R_F1PGT equation: [c] : fuc1p-L + gtp + h <==> gdpfuc + ppi
reversible: true
is: http://identifiers.org/ec-code/2.7.7.30
reactant: 781821
is: ENSCAFG00000020408.2
reactant: 781834
fast: false
reactant: 781847
name: fucose-1-phosphate guanylyltransferase
product: 781860
type: Reaction

853904
stoichiometry: 1.0
species: 753483
type: SpeciesReference

794658
stoichiometry: 1.0
species: 727166
type: SpeciesReference

764782
stoichiometry: 1.0
species: 728668
type: SpeciesReference

799437
stoichiometry: 1.0
species: 745411
type: SpeciesReference

775667
stoichiometry: 2.0
species: 753121
type: SpeciesReference

813204
stoichiometry: 1.0
species: 734211
type: SpeciesReference

809010
stoichiometry: 1.0
species: 748910
type: SpeciesReference

805690
stoichiometry: 1.0
species: 739877
type: SpeciesReference

768612
stoichiometry: 2.0
species: 741259
type: SpeciesReference

792739
stoichiometry: 1.0
species: 737654
type: SpeciesReference

031282
product: 761841
reactant: 761804
reactant: 761756
product: 761926
reversible: false
reactant: 761816
product: 761865
reactant: 761744
type: Reaction
reactant: 761768
product: 761914
reactant: 761828
is: ENSCAFG00000002826.1
product: 761853
product: 761901
reactant: 761780
is: http://identifiers.org/ec-code/2.3.1.86
product: 761889
fast: false
product: 761877
reactant: 761792
notes: R_FAEL184 subsystem: Fatty acid elongation R_FAEL184 equation: [c] : (5) h + malcoa + (4) nadph + o2 + strdnccoa --> co2 + coa + eicostetcoa + (3) h2o + (4) nadp R_FAEL183 subsystem: Fatty acid elongation R_FAEL183 equation: [c] : (5) h + lnlncgcoa + malcoa + (4) nadph + o2 --> co2 + coa + dlnlcgcoa + (3) h2o + (4) nadp R_FAEL205 subsystem: Fatty acid elongation R_FAEL205 equation: [c] : (5) h + malcoa + (4) nadph + o2 + tmndnccoa --> clpndcoa + co2 + coa + (3) h2o + (4) nadp R_FAEL204 subsystem: Fatty acid elongation R_FAEL204 equation: [c] : arachdcoa + (5) h + malcoa + (4) nadph + o2 --> adrncoa + co2 + coa + (3) h2o + (4) nadp

744133
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 4_C58H95N5O43SX
type: Species

791738
stoichiometry: 1.0
species: 747123
type: SpeciesReference

736947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10
type: Species

834120
stoichiometry: 11.0
species: 746978
type: SpeciesReference

835725
stoichiometry: 1.0
species: 744326
type: SpeciesReference

730765
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: O-Acetylcarnitine_C9H17NO4
type: Species

765476
stoichiometry: 1.0
species: 753047
type: SpeciesReference

817970
stoichiometry: 1.0
species: 747099
type: SpeciesReference

798619
stoichiometry: 6.0
species: 737103
type: SpeciesReference

835870
stoichiometry: 1.0
species: 730439
type: SpeciesReference

790234
stoichiometry: 1.0
species: 739656
type: SpeciesReference

733105
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Carbamoyl-L-aspartate_C5H6N2O5
type: Species

839437
stoichiometry: 1.0
species: 751214
type: SpeciesReference

772581
stoichiometry: 1.0
species: 739987
type: SpeciesReference

854050
stoichiometry: 2.0
species: 747099
type: SpeciesReference

749394
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Propionate (n-C3:0)_C3H5O2
type: Species

774894
stoichiometry: 1.0
species: 730922
type: SpeciesReference

815280
stoichiometry: 1.0
species: 749466
type: SpeciesReference

810531
stoichiometry: 1.0
species: 741308
type: SpeciesReference

754343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: zymosterol_C27H44O
type: Species

733568
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cholesterol_C27H46O
type: Species

809459
stoichiometry: 3.0
species: 741151
type: SpeciesReference

800798
stoichiometry: 2.0
species: 738015
type: SpeciesReference

747866
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO
type: Species

808157
stoichiometry: 1.0
species: 741899
type: SpeciesReference

734610
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 3_C37H55NO38S2
type: Species

039719
is: http://identifiers.org/ec-code/4.2.1.46
product: 840279
fast: false
is: ENSCAFG00000005327.2
product: 840267
type: Reaction
notes: R_TDPGDH subsystem: Nucleotide Sugar Metabolism R_TDPGDH equation: [c] : dtdpglu --> dtdp4d6dg + h2o
reversible: false
name: dTDPglucose 4,6-dehydratase
reactant: 840255

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 35_C68H113N4O54S1
type: Species

821016
stoichiometry: 1.0
species: 753047
type: SpeciesReference

782078
stoichiometry: 1.0
species: 726790
type: SpeciesReference

812203
stoichiometry: 1.0
species: 734030
type: SpeciesReference

735131
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate D (GlcNAc6S-GlcA2S) proteoglycan_C45H64N2O51S5X
type: Species

832965
stoichiometry: 2.0
species: 745784
type: SpeciesReference

804719
stoichiometry: 1.0
species: 751603
type: SpeciesReference

806629
stoichiometry: 1.0
species: 741440
type: SpeciesReference

793534
stoichiometry: 1.0
species: 742224
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Dihydroxyacetone phosphate_C3H5O6P
type: Species

800496
stoichiometry: 8.0
species: 741151
type: SpeciesReference

831042
stoichiometry: 1.0
species: 750104
type: SpeciesReference

796975
stoichiometry: 1.0
species: 750393
type: SpeciesReference

840508
stoichiometry: 1.0
species: 747926
type: SpeciesReference

802108
stoichiometry: 3.0
species: 741428
type: SpeciesReference

813759
stoichiometry: 1.0
species: 750020
type: SpeciesReference

779170
stoichiometry: 1.0
species: 749200
type: SpeciesReference

824541
stoichiometry: 1.0
species: 741560
type: SpeciesReference

823792
stoichiometry: 1.0
species: 731634
type: SpeciesReference

780554
stoichiometry: 1.0
species: 736704
type: SpeciesReference

790462
stoichiometry: 1.0
species: 737362
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methoxy-4-hydroxyphenylacetaldehyde_C9H10O3
type: Species

816137
stoichiometry: 1.0
species: 748218
type: SpeciesReference

789505
stoichiometry: 1.0
species: 747099
type: SpeciesReference

811420
stoichiometry: 5.0
species: 751094
type: SpeciesReference

824276
stoichiometry: 1.0
species: 742455
type: SpeciesReference

814723
stoichiometry: 1.0
species: 741259
type: SpeciesReference

816427
stoichiometry: 1.0
species: 737163
type: SpeciesReference

848631
stoichiometry: 1.0
species: 734573
type: SpeciesReference

762058
stoichiometry: 1.0
species: 730209
type: SpeciesReference

801173
stoichiometry: 1.0
species: 750962
type: SpeciesReference

032871
reversible: false
reactant: 776879
is: ENSCAFG00000023006.1
product: 776891
reactant: 776867
is: http://identifiers.org/ec-code/1.13.11.31
notes: R_ALOX12 subsystem: Eicosanoid Metabolism R_ALOX12 equation: [c] : arachd + o2 --> 12HPET
name: Arachidonate 12-lipoxygenase
fast: false
type: Reaction

843902
stoichiometry: 23.0
species: 753314
type: SpeciesReference

789807
stoichiometry: 1.0
species: 748519
type: SpeciesReference

779024
stoichiometry: 1.0
species: 753918
type: SpeciesReference

834799
stoichiometry: 6.0
species: 747173
type: SpeciesReference

806377
stoichiometry: 1.0
species: 749200
type: SpeciesReference

035023
product: 794948
reversible: false
product: 794924
reactant: 794888
product: 794936
fast: false
notes: R_MI134PP subsystem: Inositol Phosphate Metabolism R_MI134PP equation: [c] : h2o + mi134p --> mi34p + pi R_MI14PP subsystem: Inositol Phosphate Metabolism R_MI14PP equation: [c] : h2o + mi14p --> mi4p-D + pi
reactant: 794900
is: ENSCAFG00000009479.2
type: Reaction
reactant: 794912
is: http://identifiers.org/ec-code/3.1.3.57

796598
stoichiometry: 1.0
species: 751929
type: SpeciesReference

039947
product: 842050
reactant: 842026
is: ENSCAFG00000019606.2
reactant: 842038
name: hydroxyacylglutathione hydrolase
product: 842062
is: http://identifiers.org/ec-code/3.1.2.6
reversible: false
type: Reaction
fast: false
product: 842074
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D

790114
stoichiometry: 1.0
species: 745820
type: SpeciesReference

728896
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

732056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Arabinose_C5H10O5
type: Species

790895
stoichiometry: 1.0
species: 731030
type: SpeciesReference

735071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cytosine_C4H5N3O
type: Species

822043
stoichiometry: 5.0
species: 749200
type: SpeciesReference

791955
stoichiometry: 3.0
species: 731706
type: SpeciesReference

752085
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S
type: Species

841257
stoichiometry: 2.0
species: 749574
type: SpeciesReference

035239
is: http://identifiers.org/ec-code/2.3.1.21
reactant: 797982
product: 798426
product: 798282
reactant: 797734
product: 798306
product: 798234
product: 798138
type: Reaction
reactant: 798018
reactant: 797710
reactant: 797698
reactant: 797758
product: 798498
reactant: 798006
product: 798258
reactant: 798030
reactant: 798078
product: 798354
product: 798114
product: 798186
reactant: 797782
product: 798342
is: ENSCAFG00000003568.2
reactant: 797746
product: 798378
product: 798270
notes: R_LGNCCPT1 subsystem: Carnitine shuttle R_LGNCCPT1 equation: [c] : crn + lgnccoa --> coa + lgnccrn R_TETPENT3CPT1 subsystem: Carnitine shuttle R_TETPENT3CPT1 equation: [c] : crn + tetpent3coa --> coa + tetpent3crn R_ELAIDCPT1 subsystem: Carnitine shuttle R_ELAIDCPT1 equation: [c] : crn + od2coa --> coa + elaidcrn R_ADRNCPT1 subsystem: Carnitine shuttle R_ADRNCPT1 equation: [c] : adrncoa + crn --> adrncrn + coa R_DCSPTN1CPT1 subsystem: Carnitine shuttle R_DCSPTN1CPT1 equation: [c] : crn + dcsptn1coa --> coa + dcsptn1crn R_C204CPT1 subsystem: Carnitine shuttle R_C204CPT1 equation: [c] : arachdcoa + crn --> arachdcrn + coa R_DLNLCGCPT1 subsystem: Carnitine shuttle R_DLNLCGCPT1 equation: [c] : crn + dlnlcgcoa --> coa + dlnlcgcrn R_TMNDNCCPT1 subsystem: Carnitine shuttle R_TMNDNCCPT1 equation: [c] : crn + tmndnccoa --> coa + tmndnccrn R_C180CPT1 subsystem: Carnitine shuttle R_C180CPT1 equation: [c] : crn + stcoa --> coa + stcrn R_LNLNCGCPT1 subsystem: Carnitine shuttle R_LNLNCGCPT1 equation: [c] : crn + lnlncgcoa --> coa + lnlncgcrn R_TTDCPT1 subsystem: Carnitine shuttle R_TTDCPT1 equation: [c] : crn + tdcoa --> coa + ttdcrn R_NRVNCCPT1 subsystem: Carnitine shuttle R_NRVNCCPT1 equation: [c] : crn + nrvnccoa --> coa + nrvnccrn R_LNLNCACPT1 subsystem: Carnitine shuttle R_LNLNCACPT1 equation: [c] : crn + lnlncacoa --> coa + lnlncacrn R_VACCCPT1 subsystem: Carnitine shuttle R_VACCCPT1 equation: [c] : crn + vacccoa --> coa + vacccrn R_PTDCACRNCPT1 subsystem: Carnitine shuttle R_PTDCACRNCPT1 equation: [c] : crn + ptdcacoa --> coa + ptdcacrn R_CLPNDCPT1 subsystem: Carnitine shuttle R_CLPNDCPT1 equation: [c] : clpndcoa + crn --> clpndcrn + coa R_EICOSTETCPT1 subsystem: Carnitine shuttle R_EICOSTETCPT1 equation: [c] : crn + eicostetcoa --> coa + eicostetcrn R_C160CPT1 subsystem: Carnitine shuttle R_C160CPT1 equation: [c] : crn + pmtcoa --> coa + pmtcrn R_RTOTAL3CRNCPT1 subsystem: Carnitine shuttle R_RTOTAL3CRNCPT1 equation: [c] : Rtotal3coa + crn --> Rtotal3crn + coa R_LNLCCPT1 s…
reactant: 797857
reactant: 797970
reactant: 798066
product: 798462
reactant: 797844
product: 798438
product: 798294
reactant: 798042
reactant: 797795
reactant: 797831
reactant: 797722
reactant: 797946
reactant: 798102
product: 798318
reactant: 798090
product: 798150
reactant: 798054
reactant: 797870
product: 798402
reactant: 797958
is: ENSCAFG00000010757.1
reactant: 797994
product: 798174
product: 798366
product: 798126
product: 798510
product: 798222
reactant: 797807
reactant: 797896
product: 798450
product: 798210
reactant: 797883
fast: false
product: 798486
product: 798390
product: 798246
reactant: 797819
product: 798474
reactant: 797909
reactant: 797934
reversible: false
product: 798330
product: 798162
product: 798198
product: 798414
reactant: 797770
reactant: 797922

816210
stoichiometry: 1.0
species: 748206
type: SpeciesReference

815957
stoichiometry: 1.0
species: 741223
type: SpeciesReference

766955
stoichiometry: 1.0
species: 741259
type: SpeciesReference

769047
stoichiometry: 1.0
species: 739123
type: SpeciesReference

726584
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _1-alpha,25-Dihydroxyvitamin D2_C28H44O3
type: Species

739815
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucose_C6H12O6
type: Species

782499
stoichiometry: 1.0
species: 738231
type: SpeciesReference

796381
stoichiometry: 103.0
species: 741199
type: SpeciesReference

728740
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _5-Hydroxy-L-tryptophan_C11H12N2O3
type: Species

728245
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _4-Methylzymosterol intermediate 1_C29H46O3
type: Species

854352
stoichiometry: 9.0
species: 741078
type: SpeciesReference

788204
stoichiometry: 1.0
species: 754281
type: SpeciesReference

743168
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 14_C166H267N11O145S8
type: Species

835195
stoichiometry: 1.0
species: 743685
type: SpeciesReference

854629
stoichiometry: 3.0
species: 735228
type: SpeciesReference

818653
stoichiometry: 1.0
species: 739802
type: SpeciesReference

745928
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Malonyl-CoA_C24H33N7O19P3S
type: Species

788878
stoichiometry: 5.0
species: 747062
type: SpeciesReference

855134
stoichiometry: 1.0
species: 730052
type: SpeciesReference

038864
fast: false
notes: R_MELATNOX subsystem: Tryptophan metabolism R_MELATNOX equation: [c] : h + melatn + nadph + o2 --> 6hoxmelatn + h2o + nadp
reactant: 832124
product: 832196
reversible: false
is: ENSCAFG00000017937.2
product: 832172
is: ENSCAFG00000017941.2
type: Reaction
is: http://identifiers.org/ec-code/1.14.14.1
reactant: 832160
reactant: 832148
product: 832184
name: Melatonin:NADP oxidoreductase
reactant: 832136

755297
stoichiometry: 1.0
species: 747185
type: SpeciesReference

847836
stoichiometry: 6.0
species: 739939
type: SpeciesReference

783716
stoichiometry: 1.0
species: 753555
type: SpeciesReference

037267
reactant: 816415
is: http://identifiers.org/ec-code/3.1.3.5
product: 816500
reactant: 816366
reactant: 816342
notes: R_NTD7l subsystem: Nucleic acid degradation R_NTD7l equation: [l] : amp + h2o --> adn + pi R_NTD9l subsystem: Nucleic acid degradation R_NTD9l equation: [l] : gmp + h2o --> gsn + pi R_NTD4l subsystem: Nucleic acid degradation R_NTD4l equation: [l] : cmp + h2o --> cytd + pi R_NTD3l subsystem: Nucleic acid degradation R_NTD3l equation: [l] : dcmp + h2o --> dcyt + pi R_NTD8l subsystem: Nucleic acid degradation R_NTD8l equation: [l] : dgmp + h2o --> dgsn + pi R_NTD2l subsystem: Nucleic acid degradation R_NTD2l equation: [l] : h2o + ump --> pi + uri R_LAPCOAl subsystem: CoA Catabolism R_LAPCOAl equation: [l] : coa + h2o --> dpcoa + pi R_NTD5l subsystem: Nucleic acid degradation R_NTD5l equation: [l] : dtmp + h2o --> pi + thymd R_3NTD7l subsystem: Nucleic acid degradation R_3NTD7l equation: [l] : 3amp + h2o --> adn + pi R_NTD6l subsystem: Nucleic acid degradation R_NTD6l equation: [l] : damp + h2o --> dad-2 + pi
reactant: 816452
is: ENSCAFG00000008833.2
fast: false
product: 816512
reactant: 816439
reactant: 816330
product: 816464
product: 816524
reversible: false
product: 816476
reactant: 816379
product: 816536
reactant: 816403
reactant: 816354
product: 816560
product: 816488
product: 816548
type: Reaction
product: 816572
reactant: 816391
reactant: 816427

748603
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2
type: Species

801599
stoichiometry: 1.0
species: 746726
type: SpeciesReference

038791
type: Reaction
reversible: false
product: 831678
name: retinyl ester hydrolase
notes: R_RETH subsystem: Vitamin A Metabolism R_RETH equation: [c] : h2o + retfa --> Rtotal2 + h + retinol
product: 831654
fast: false
reactant: 831642
is: ENSCAFG00000011294.1
reactant: 831630
product: 831666

758690
stoichiometry: 1.0
species: 738255
type: SpeciesReference

820376
stoichiometry: 1.0
species: 745687
type: SpeciesReference

821751
stoichiometry: 1.0
species: 741259
type: SpeciesReference

753447
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: UMP_C9H11N2O9P
type: Species

773535
stoichiometry: 1.0
species: 751530
type: SpeciesReference

793846
stoichiometry: 1.0
species: 750032
type: SpeciesReference

769908
stoichiometry: 1.0
species: 747050
type: SpeciesReference

852111
stoichiometry: 1.0
species: 747379
type: SpeciesReference

831318
stoichiometry: 1.0
species: 753157
type: SpeciesReference

744534
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 9_C83H133N7O64S2X
type: Species

770510
stoichiometry: 2.0
species: 734005
type: SpeciesReference

756896
stoichiometry: 1.0
species: 735011
type: SpeciesReference

759922
stoichiometry: 1.0
species: 746774
type: SpeciesReference

845523
stoichiometry: 1.0
species: 749067
type: SpeciesReference

844663
stoichiometry: 1.0
species: 726924
type: SpeciesReference

834554
stoichiometry: 3.0
species: 734054
type: SpeciesReference

792438
stoichiometry: 1.0
species: 738918
type: SpeciesReference

826894
stoichiometry: 1.0
species: 735421
type: SpeciesReference

762919
stoichiometry: 1.0
species: 753072
type: SpeciesReference

844071
stoichiometry: 1.0
species: 743963
type: SpeciesReference

733666
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: chitin_C24H41N3O16
type: Species

745097
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: linoelaidyl coenzyme A_C39H62N7O17P3S
type: Species

774386
stoichiometry: 1.0
species: 741223
type: SpeciesReference

752193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tetracosatetraenoyl carnitine_C31H53NO4
type: Species

750998
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenocystathionine_C7H14N2O4Se
type: Species

810760
stoichiometry: 1.0
species: 726766
type: SpeciesReference

802664
stoichiometry: 2.0
species: 741163
type: SpeciesReference

834481
stoichiometry: 1.0
species: 737326
type: SpeciesReference

747758
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: O2_O2
type: Species

035131
reactant: 795910
reactant: 795898
reversible: false
type: Reaction
reactant: 795802
reactant: 795874
product: 796067
notes: R_B3GNT11g subsystem: Blood Group Biosynthesis R_B3GNT11g equation: [g] : gal14acglcgalgluside_hs + uacgam --> acglcgal14acglcgalgluside_hs + h + udp R_AG13T6g subsystem: Keratan sulfate biosynthesis R_AG13T6g equation: [g] : ksi_pre6 + uacgam --> h + ksi_pre7 + udp R_AG13T17g subsystem: Keratan sulfate biosynthesis R_AG13T17g equation: [g] : ksii_core4_pre4 + uacgam --> h + ksii_core4_pre5 + udp R_B3GNT12g subsystem: Blood Group Biosynthesis R_B3GNT12g equation: [g] : galacglcgal14acglcgalgluside_hs + uacgam --> acglc13galacglcgal14acglcgalgluside_hs + h + udp R_AG13T2g subsystem: Keratan sulfate biosynthesis R_AG13T2g equation: [g] : ksii_core2_pre4 + uacgam --> h + ksii_core2_pre5 + udp R_AG13T5g subsystem: Keratan sulfate biosynthesis R_AG13T5g equation: [g] : ksi_pre3 + uacgam --> h + ksi_pre4 + udp R_AG13T8g subsystem: Keratan sulfate biosynthesis R_AG13T8g equation: [g] : ksi_pre12 + uacgam --> h + ksi_pre13 + udp R_AG13T12g subsystem: Keratan sulfate biosynthesis R_AG13T12g equation: [g] : ksi_pre24 + uacgam --> h + ksi_pre25 + udp R_AG13T1g subsystem: Keratan sulfate biosynthesis R_AG13T1g equation: [g] : ksii_core2_pre2 + uacgam --> h + ksii_core2_pre3 + udp R_AG13T10g subsystem: Keratan sulfate biosynthesis R_AG13T10g equation: [g] : ksi_pre18 + uacgam --> h + ksi_pre19 + udp R_AG13T14g subsystem: Keratan sulfate biosynthesis R_AG13T14g equation: [g] : ksi_pre30 + uacgam --> h + ksi_pre31 + udp R_AG13T13g subsystem: Keratan sulfate biosynthesis R_AG13T13g equation: [g] : ksi_pre27 + uacgam --> h + ksi_pre28 + udp R_AG13T9g subsystem: Keratan sulfate biosynthesis R_AG13T9g equation: [g] : ksi_pre15 + uacgam --> h + ksi_pre16 + udp R_AG13T15g subsystem: Keratan sulfate biosynthesis R_AG13T15g equation: [g] : ksi_pre33 + uacgam --> h + ksi_pre34 + udp R_AG13T4g subsystem: Keratan sulfate biosynthesis R_AG13T4g equation: [g] : ksi_pre1 + uacgam --> h + ksi_pre2 + udp R_AG13T11g subsystem: Keratan sulfate biosynthesis R_AG13T11g equation: [g] : ksi_pre21 + uac…
product: 796019
reactant: 795730
product: 796043
product: 796116
reactant: 795694
product: 796140
is: ENSCAFG00000003094.2
reactant: 795886
product: 796092
product: 795971
fast: false
product: 796188
product: 796079
product: 796164
product: 795959
reactant: 795838
reactant: 795766
reactant: 795850
reactant: 795922
product: 796055
reactant: 795790
is: http://identifiers.org/ec-code/2.4.1.149
reactant: 795742
reactant: 795935
reactant: 795778
product: 796200
reactant: 795862
product: 796104
reactant: 795754
product: 796176
product: 796152
product: 796128
product: 796031
product: 796007
product: 795995
reactant: 795706
product: 795947
reactant: 795814
reactant: 795718
product: 795983
reactant: 795826

765119
stoichiometry: 1.0
species: 734054
type: SpeciesReference

790570
stoichiometry: 10.0
species: 730922
type: SpeciesReference

750153
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2
type: Species

784067
stoichiometry: 1.0
species: 728668
type: SpeciesReference

784923
stoichiometry: 1.0
species: 728293
type: SpeciesReference

804308
stoichiometry: 1.0
species: 728764
type: SpeciesReference

848523
stoichiometry: 33.0
species: 730184
type: SpeciesReference

845063
stoichiometry: 3.0
species: 740023
type: SpeciesReference

854737
stoichiometry: 1.0
species: 741187
type: SpeciesReference

735288
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cytidine_C9H13N3O5
type: Species

036965
notes: R_UDPGLCtg subsystem: Transport, Golgi Apparatus R_UDPGLCtg equation: udpg[c] + ump[g] <==> udpg[g] + ump[c] R_UGLCNACtg subsystem: Transport, Golgi Apparatus R_UGLCNACtg equation: uacgam[c] + ump[g] <==> uacgam[g] + ump[c]
fast: false
reversible: true
reactant: 813288
type: Reaction
reactant: 813312
product: 813349
reactant: 813300
is: ENSCAFG00000001216.2
product: 813337
product: 813325

030657
notes: R_LGTHL subsystem: Pyruvate Metabolism R_LGTHL equation: [c] : gthrd + mthgxl --> lgt-S
name: lactoylglutathione lyase
product: 756394
reactant: 756382
is: http://identifiers.org/ec-code/4.4.1.5
fast: false
is: ENSCAFG00000001493.2
reactant: 756370
type: Reaction
reversible: false

812806
stoichiometry: 1.0
species: 736983
type: SpeciesReference

808397
stoichiometry: 1.0
species: 729907
type: SpeciesReference

830349
stoichiometry: 1.0
species: 748699
type: SpeciesReference

845232
stoichiometry: 1.0
species: 749200
type: SpeciesReference

842626
stoichiometry: 4.0
species: 741332
type: SpeciesReference

759811
stoichiometry: 1.0
species: 748495
type: SpeciesReference

795730
stoichiometry: 1.0
species: 744012
type: SpeciesReference

850839
stoichiometry: 1.0
species: 747173
type: SpeciesReference

816029
stoichiometry: 2.0
species: 741259
type: SpeciesReference

733213
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: CDP_C9H12N3O11P2
type: Species

810195
stoichiometry: 1.0
species: 743000
type: SpeciesReference

794355
stoichiometry: 1.0
species: 733859
type: SpeciesReference

038573
product: 830071
reactant: 830047
fast: false
type: Reaction
is: ENSCAFG00000003065.2
product: 830059
reactant: 830035
notes: R_CMPACNAtg subsystem: Transport, Golgi Apparatus R_CMPACNAtg equation: cmp[g] + cmpacna[c] <==> cmp[c] + cmpacna[g]
reversible: true
name: CMP-Sia Golgi transport via CMP antiport

732817
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Biotin_C10H15N2O3S
type: Species

761465
stoichiometry: 1.0
species: 748399
type: SpeciesReference

736656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: N,N-Dimethylglycine_C4H9NO2
type: Species

726692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2,3-Disphospho-D-glycerate_C3H3O10P2
type: Species

851008
stoichiometry: 1.0
species: 741199
type: SpeciesReference

805538
stoichiometry: 1.0
species: 739486
type: SpeciesReference

794900
stoichiometry: 2.0
species: 741151
type: SpeciesReference

804016
stoichiometry: 1.0
species: 741971
type: SpeciesReference

757516
stoichiometry: 1.0
species: 745735
type: SpeciesReference

807869
stoichiometry: 2.0
species: 732441
type: SpeciesReference

777665
stoichiometry: 1.0
species: 753133
type: SpeciesReference

762167
stoichiometry: 1.0
species: 748699
type: SpeciesReference

801064
stoichiometry: 1.0
species: 735601
type: SpeciesReference

035347
reactant: 799689
product: 799774
product: 799749
type: Reaction
product: 799761
fast: false
product: 799737
is: ENSCAFG00000001623.2
reversible: true
is: ENSCAFG00000023808.1
reactant: 799701
reactant: 799725
notes: R_NCKt subsystem: Transport, Extracellular R_NCKt equation: ca2[e] + k[e] + (4) na1[c] <==> ca2[c] + k[c] + (4) na1[e] R_NCNt subsystem: Transport, Extracellular R_NCNt equation: ca2[e] + (4) na1[c] + nh4[e] <==> ca2[c] + (4) na1[e] + nh4[c]
is: ENSCAFG00000017247.2
reactant: 799713

823310
stoichiometry: 3.0
species: 736086
type: SpeciesReference

844555
stoichiometry: 1.0
species: 730221
type: SpeciesReference

793954
stoichiometry: 2.0
species: 741308
type: SpeciesReference

852003
stoichiometry: 1.0
species: 733033
type: SpeciesReference

810976
stoichiometry: 1.0
species: 730946
type: SpeciesReference

815051
stoichiometry: 1.0
species: 752545
type: SpeciesReference

752902
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: testosterone glucuronide_C25H36O8
type: Species

803230
stoichiometry: 1.0
species: 749466
type: SpeciesReference

728354
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Trimethylammoniobutanal_C7H16NO
type: Species

764939
stoichiometry: 1.0
species: 740349
type: SpeciesReference

836689
stoichiometry: 1.0
species: 747830
type: SpeciesReference

746581
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: myo-Inositol hexakisphosphate_C6H6O24P6
type: Species

819390
stoichiometry: 1.0
species: 750297
type: SpeciesReference

766846
stoichiometry: 2.0
species: 749466
type: SpeciesReference

846016
stoichiometry: 1.0
species: 726283
type: SpeciesReference

767027
stoichiometry: 3.0
species: 741151
type: SpeciesReference

032943
name: _6-phosphogluconolactonase
fast: false
is: http://identifiers.org/ec-code/3.1.1.31
product: 777384
reactant: 777348
is: ENSCAFG00000015270.2
product: 777372
type: Reaction
reactant: 777360
reversible: false
notes: R_PGL subsystem: Pentose Phosphate Pathway R_PGL equation: [c] : 6pgl + h2o --> 6pgc + h

847570
stoichiometry: 1.0
species: 733762
type: SpeciesReference

773643
stoichiometry: 1.0
species: 732260
type: SpeciesReference

811902
stoichiometry: 1.0
species: 731706
type: SpeciesReference

816644
stoichiometry: 5.0
species: 748687
type: SpeciesReference

825338
stoichiometry: 3.0
species: 735409
type: SpeciesReference

734939
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 4_C31H46NO38S4
type: Species

840907
stoichiometry: 3.0
species: 741115
type: SpeciesReference

847728
stoichiometry: 1.0
species: 740180
type: SpeciesReference

733455
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

034420
is: ENSCAFG00000023358.1
product: 789723
reactant: 789663
product: 789699
type: Reaction
fast: false
product: 789711
reactant: 789675
reactant: 789687
notes: R_NRPPHRtu subsystem: Transport, Extracellular R_NRPPHRtu equation: nrpphr[e] <==> nrpphr[c] R_DOPAtu subsystem: Transport, Extracellular R_DOPAtu equation: dopa[e] <==> dopa[c] R_HISTAtu subsystem: Transport, Extracellular R_HISTAtu equation: hista[e] <==> hista[c]
reversible: true

743012
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Itaconate_C5H4O4
type: Species

835087
stoichiometry: 1.0
species: 730476
type: SpeciesReference

851665
stoichiometry: 1.0
species: 737750
type: SpeciesReference

824699
stoichiometry: 1.0
species: 751470
type: SpeciesReference

753555
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Urea_CH4N2O
type: Species

843286
stoichiometry: 1.0
species: 744784
type: SpeciesReference

789735
stoichiometry: 1.0
species: 741151
type: SpeciesReference

040308
name: beta-D-Glucosyl-2-coumarinate glucohydrolase
is: http://identifiers.org/ec-code/3.2.1.21
product: 845487
reactant: 845451
fast: false
is: ENSCAFG00000016529.2
reactant: 845463
product: 845475
type: Reaction
product: 845499
notes: R_BDG2HCGHD subsystem: Stilbene, coumarine and lignin biosynthesis R_BDG2HCGHD equation: [c] : bdg2hc + h2o --> 2coum + glc-D + h
reversible: false

780446
stoichiometry: 1.0
species: 731127
type: SpeciesReference

854460
stoichiometry: 1.0
species: 741777
type: SpeciesReference

038209
reactant: 827125
notes: R_3HAO subsystem: Tryptophan metabolism R_3HAO equation: [c] : 3hanthrn + o2 --> cmusa + h
reactant: 827137
is: ENSCAFG00000002435.2
product: 827149
product: 827161
name: _3-hydroxyanthranilate 3,4-dioxygenase
fast: false
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/1.13.11.6

849658
stoichiometry: 1.0
species: 734658
type: SpeciesReference

030765
notes: R_ABUTt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_ABUTt4_LPAREN_2_RPAREN_r equation: _4abut[e] + (2) na1[e] <==> 4abut[c] + (2) na1[c]
reversible: true
fast: false
product: 757687
name: _4-aminobutyrate reversible transport in via sodium symport (1:2)
reactant: 757663
is: ENSCAFG00000005033.2
type: Reaction
is: ENSCAFG00000015769.2
product: 757699
reactant: 757675
is: ENSCAFG00000023412.1

755188
stoichiometry: 1.0
species: 741151
type: SpeciesReference

820485
stoichiometry: 1.0
species: 736328
type: SpeciesReference

795886
stoichiometry: 1.0
species: 744471
type: SpeciesReference

827221
stoichiometry: 1.0
species: 734091
type: SpeciesReference

842776
stoichiometry: 1.0
species: 748483
type: SpeciesReference

736231
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dihydroceramide (homo sapiens)_C18H38NO2FULLRCO
type: Species

739963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Glutamate 5-phosphate_C5H8NO7P
type: Species

774918
stoichiometry: 1.0
species: 726259
type: SpeciesReference

791099
stoichiometry: 1.0
species: 751591
type: SpeciesReference

838325
stoichiometry: 2.0
species: 741332
type: SpeciesReference

771481
stoichiometry: 1.0
species: 733921
type: SpeciesReference

754776
stoichiometry: 1.0
species: 747099
type: SpeciesReference

803676
stoichiometry: 1.0
species: 753230
type: SpeciesReference

752313
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO
type: Species

842410
stoichiometry: 3.0
species: 747099
type: SpeciesReference

767243
stoichiometry: 1.0
species: 747209
type: SpeciesReference

771625
stoichiometry: 1.0
species: 749466
type: SpeciesReference

797970
stoichiometry: 1.0
species: 751470
type: SpeciesReference

817150
stoichiometry: 1.0
species: 752265
type: SpeciesReference

740590
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GlcNAc-alpha-1,4-Core 1_C22H37N2O15X
type: Species

838481
stoichiometry: 1.0
species: 729738
type: SpeciesReference

745784
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X
type: Species

821233
stoichiometry: 1.0
species: 748375
type: SpeciesReference

785019
stoichiometry: 2.0
species: 741308
type: SpeciesReference

753181
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: UDP_C9H11N2O12P2
type: Species

735577
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dCDP_C9H12N3O10P2
type: Species

040729
modifier: 851521
reversible: false
is: http://identifiers.org/ec-code/1.1.1.27
product: 851401
modifier: 851485
reactant: 851350
is: http://identifiers.org/ec-code/1.2.3.5
is: ENSCAFG00000009323.2
modifier: 851461
product: 851389
modifier: 851497
reactant: 851376
modifier: 851437
product: 851413
modifier: 851425
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
fast: false
modifier: 851473
reactant: 851363
type: Reaction
modifier: 851509
modifier: 851449

780013
stoichiometry: 1.0
species: 733678
type: SpeciesReference

787602
stoichiometry: 1.0
species: 749200
type: SpeciesReference

830801
stoichiometry: 1.0
species: 741283
type: SpeciesReference

833820
stoichiometry: 1.0
species: 732829
type: SpeciesReference

832316
stoichiometry: 1.0
species: 736947
type: SpeciesReference

030489
is: http://identifiers.org/ec-code/3.6.1.5
reactant: 755249
reactant: 755237
is: ENSCAFG00000005128.1
product: 755285
fast: false
is: ENSCAFG00000019522.1
reactant: 755225
product: 755261
is: ENSCAFG00000019892.2
is: ENSCAFG00000004371.2
is: ENSCAFG00000025238.1
type: Reaction
reversible: false
product: 755273
notes: R_ATPH2e subsystem: Nucleotides R_ATPH2e equation: [e] : adp + h2o --> amp + h + pi R_ATPH1e subsystem: Nucleotides R_ATPH1e equation: [e] : atp + (2) h2o --> amp + (2) h + (2) pi

778506
stoichiometry: 1.0
species: 753567
type: SpeciesReference

766097
stoichiometry: 1.0
species: 748073
type: SpeciesReference

767894
stoichiometry: 6.0
species: 749466
type: SpeciesReference

817862
stoichiometry: 1.0
species: 737151
type: SpeciesReference

728498
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5alpha-Dihydrotestosterone sulfate_C19H29O5S
type: Species

835653
stoichiometry: 1.0
species: 730488
type: SpeciesReference

804587
stoichiometry: 1.0
species: 751506
type: SpeciesReference

840749
stoichiometry: 111.0
species: 747002
type: SpeciesReference

782342
stoichiometry: 1.0
species: 733491
type: SpeciesReference

848281
stoichiometry: 1.0
species: 751591
type: SpeciesReference

823165
stoichiometry: 1.0
species: 734005
type: SpeciesReference

730657
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: N-Acetylneuraminate_C11H18NO9
type: Species

746485
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3
type: Species

825928
stoichiometry: 3.0
species: 740970
type: SpeciesReference

801488
stoichiometry: 1.0
species: 752790
type: SpeciesReference

827846
stoichiometry: 1.0
species: 748266
type: SpeciesReference

813312
stoichiometry: 2.0
species: 753423
type: SpeciesReference

775739
stoichiometry: 1.0
species: 740603
type: SpeciesReference

765729
stoichiometry: 1.0
species: 737606
type: SpeciesReference

743721
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 15_C149H240N10O119S4X
type: Species

731139
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adrenyl carnitine_C29H49NO4
type: Species

848958
stoichiometry: 1.0
species: 734915
type: SpeciesReference

779591
stoichiometry: 1.0
species: 739619
type: SpeciesReference

771782
stoichiometry: 1.0
species: 739939
type: SpeciesReference

816366
stoichiometry: 1.0
species: 735613
type: SpeciesReference

777878
stoichiometry: 1.0
species: 738762
type: SpeciesReference

769288
stoichiometry: 1.0
species: 733981
type: SpeciesReference

793570
stoichiometry: 1.0
species: 742164
type: SpeciesReference

835509
stoichiometry: 1.0
species: 743805
type: SpeciesReference

741705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S
type: Species

753034
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Thromboxane A2_C20H31O5
type: Species

850911
stoichiometry: 1.0
species: 740651
type: SpeciesReference

732683
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Bilirubin_C33H34N4O6
type: Species

764360
stoichiometry: 1.0
species: 747173
type: SpeciesReference

754560
stoichiometry: 1.0
species: 734598
type: SpeciesReference

766292
stoichiometry: 1.0
species: 745097
type: SpeciesReference

834277
stoichiometry: 1.0
species: 727955
type: SpeciesReference

845920
stoichiometry: 1.0
species: 728860
type: SpeciesReference

793270
stoichiometry: 1.0
species: 745711
type: SpeciesReference

764673
stoichiometry: 1.0
species: 750369
type: SpeciesReference

828520
stoichiometry: 1.0
species: 747553
type: SpeciesReference

805117
stoichiometry: 1.0
species: 752205
type: SpeciesReference

814831
stoichiometry: 2.0
species: 741259
type: SpeciesReference

801879
stoichiometry: 1.0
species: 728486
type: SpeciesReference

727967
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Acetamidobutanoate_C6H10NO3
type: Species

794501
stoichiometry: 1.0
species: 741838
type: SpeciesReference

799172
stoichiometry: 1.0
species: 753230
type: SpeciesReference

806136
stoichiometry: 2.0
species: 746750
type: SpeciesReference

753834
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: omega hydroxy hexadecanoate (n-C16:0)_C16H31O3
type: Species

792004
stoichiometry: 3.0
species: 731309
type: SpeciesReference

841677
stoichiometry: 1.0
species: 739196
type: SpeciesReference

832100
stoichiometry: 1.0
species: 732332
type: SpeciesReference

775318
stoichiometry: 1.0
species: 728884
type: SpeciesReference

786798
stoichiometry: 1.0
species: 749297
type: SpeciesReference

791365
stoichiometry: 1.0
species: 744976
type: SpeciesReference

765584
stoichiometry: 1.0
species: 728281
type: SpeciesReference

761319
stoichiometry: 1.0
species: 729858
type: SpeciesReference

033342
reactant: 780085
product: 780169
reactant: 780121
reactant: 780097
reactant: 780109
reactant: 780037
product: 780145
product: 780205
reactant: 780061
is: http://identifiers.org/ec-code/3.5.1.12
reactant: 780073
type: Reaction
product: 780157
reversible: false
reactant: 780049
product: 780181
is: ENSCAFG00000005929.2
product: 780217
notes: R_BTND1 subsystem: Biotin Metabolism R_BTND1 equation: [c] : biocyt + h2o --> btn + lys-L R_BTND1n subsystem: Biotin Metabolism R_BTND1n equation: [n] : biocyt + h2o --> btn + lys-L R_BTNDe subsystem: Biotin Metabolism R_BTNDe equation: [e] : biocyt + h2o --> btn + lys-L R_BTNDm subsystem: Biotin Metabolism R_BTNDm equation: [m] : biocyt + h2o --> btn + lys-L
fast: false
product: 780133
product: 780193

838193
stoichiometry: 1.0
species: 749466
type: SpeciesReference

790342
stoichiometry: 1.0
species: 737278
type: SpeciesReference

762857
stoichiometry: 1.0
species: 732260
type: SpeciesReference

754620
stoichiometry: 3.0
species: 751227
type: SpeciesReference

809302
stoichiometry: 1.0
species: 739913
type: SpeciesReference

775510
stoichiometry: 2.0
species: 738195
type: SpeciesReference

774785
stoichiometry: 1.0
species: 737399
type: SpeciesReference

731297
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: S-Adenosyl-L-homocysteine_C14H20N6O5S
type: Species

770245
stoichiometry: 1.0
species: 746074
type: SpeciesReference

032643
reversible: false
fast: false
product: 774773
product: 774749
reactant: 774737
is: ENSCAFG00000003010.2
name: Ceramide glucosyltransferase
notes: R_UGCG subsystem: Sphingolipid Metabolism R_UGCG equation: [r] : crm_hs + udpg --> gluside_hs + h + udp
is: http://identifiers.org/ec-code/2.4.1.80
reactant: 774725
type: Reaction
product: 774761

804163
stoichiometry: 1.0
species: 741247
type: SpeciesReference

839546
stoichiometry: 1.0
species: 751082
type: SpeciesReference

784611
stoichiometry: 2.0
species: 741151
type: SpeciesReference

800388
stoichiometry: 3.0
species: 751470
type: SpeciesReference

037182
reactant: 815630
product: 815726
fast: false
product: 815702
notes: R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp R_GLCNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT1g equation: [g] : cs,hs_linkage + uacgam --> h + hs_pre1 + udp
product: 815738
product: 815678
product: 815690
is: ENSCAFG00000008284.2
product: 815714
reactant: 815642
reactant: 815594
reversible: false
reactant: 815654
type: Reaction
reactant: 815606
product: 815666
reactant: 815618

738582
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: L-Fucose_C6H12O5
type: Species

855437
stoichiometry: 2.0
species: 741139
type: SpeciesReference

831150
stoichiometry: 1.0
species: 735264
type: SpeciesReference

792450
stoichiometry: 1.0
species: 746038
type: SpeciesReference

036736
product: 811264
reactant: 811252
notes: R_MI1PS subsystem: Inositol Phosphate Metabolism R_MI1PS equation: [c] : g6p --> mi1p-D
is: ENSCAFG00000014817.2
is: http://identifiers.org/ec-code/5.5.1.4
fast: false
reversible: false
name: myo-Inositol-1-phosphate synthase
type: Reaction

035961
reactant: 804247
reactant: 804260
is: http://identifiers.org/ec-code/4.1.1.28
product: 804321
product: 804272
product: 804284
reactant: 804175
product: 804345
reversible: false
reactant: 804199
reactant: 804163
notes: R_5HXKYNDCL subsystem: Tryptophan metabolism R_5HXKYNDCL equation: [c] : 5hxkyn + h --> 5hxkynam + co2 R_HISDC subsystem: Histidine Metabolism R_HISDC equation: [c] : h + his-L --> co2 + hista R_TYRCBOX subsystem: Tyrosine metabolism R_TYRCBOX equation: [c] : h + tyr-L --> co2 + tym R_5HLTDL subsystem: Tryptophan metabolism R_5HLTDL equation: [c] : 5htrp + h --> co2 + srtn R_PHYCBOXL subsystem: Phenylalanine metabolism R_PHYCBOXL equation: [c] : h + phe-L --> co2 + peamn R_LTDCL subsystem: Tryptophan metabolism R_LTDCL equation: [c] : h + trp-L --> co2 + trypta R_3HXKYNDCL subsystem: Tryptophan metabolism R_3HXKYNDCL equation: [c] : h + hLkynr --> 3hxkynam + co2 R_3HLYTCL subsystem: Tyrosine metabolism R_3HLYTCL equation: [c] : 34dhphe + h --> co2 + dopa
product: 804308
fast: false
is: ENSCAFG00000003400.2
reactant: 804187
reactant: 804211
type: Reaction
is: http://identifiers.org/ec-code/4.1.1.22
is: http://identifiers.org/ec-code/4.1.1.25
product: 804370
product: 804333
reactant: 804235
product: 804296
product: 804357
reactant: 804223

747002
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

035816
product: 803122
notes: R_PROt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_PROt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + pro-L[e] <==> (2) na1[c] + pro-L[c]
fast: false
name: Proline transport (sodium symport) (2:1)
is: ENSCAFG00000018203.2
reactant: 803098
product: 803110
type: Reaction
reversible: true
reactant: 803086

777023
stoichiometry: 1.0
species: 752229
type: SpeciesReference

799581
stoichiometry: 1.0
species: 750333
type: SpeciesReference

762422
stoichiometry: 4.0
species: 751251
type: SpeciesReference

768427
stoichiometry: 1.0
species: 740023
type: SpeciesReference

727396
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

789965
stoichiometry: 6.0
species: 746930
type: SpeciesReference

833170
stoichiometry: 1.0
species: 736376
type: SpeciesReference

728149
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: trans-4-Hydroxy-L-proline_C5H9NO3
type: Species

797650
stoichiometry: 1.0
species: 748302
type: SpeciesReference

812662
stoichiometry: 1.0
species: 747553
type: SpeciesReference

040489
type: Reaction
reactant: 847426
product: 847474
product: 847462
is: ENSCAFG00000000946.2
fast: false
product: 847510
reactant: 847438
reversible: false
reactant: 847450
reactant: 847414
notes: R_A4GALTg subsystem: Sphingolipid Metabolism R_A4GALTg equation: [g] : galgluside_hs + udpgal --> h + thcrm_hs + udp R_A4GALTc subsystem: Sphingolipid Metabolism R_A4GALTc equation: [c] : galgluside_hs + udpgal --> h + thcrm_hs + udp
product: 847522
product: 847498
product: 847486

730052
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Acetoacetate_C4H5O3
type: Species

844784
stoichiometry: 1.0
species: 730209
type: SpeciesReference

038040
reactant: 825904
notes: R_ADK1 subsystem: Nucleotides R_ADK1 equation: [c] : amp + atp <==> (2) adp R_ADK3 subsystem: Nucleotides R_ADK3 equation: [c] : amp + gtp <==> adp + gdp R_CYTK4 subsystem: Nucleotides R_CYTK4 equation: [c] : dcmp + gtp <==> dcdp + gdp R_CYTK3 subsystem: Nucleotides R_CYTK3 equation: [c] : cmp + gtp <==> cdp + gdp R_ADKd subsystem: Nucleotides R_ADKd equation: [c] : damp + datp <==> (2) dadp
is: ENSCAFG00000020380.2
reactant: 825964
reactant: 825928
is: http://identifiers.org/ec-code/2.7.4.3
reactant: 825892
product: 826013
product: 825976
reactant: 825940
product: 826025
product: 826000
product: 825988
reactant: 825952
fast: false
type: Reaction
reactant: 825916
reversible: true

740874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO
type: Species

757747
stoichiometry: 1.0
species: 726548
type: SpeciesReference

778940
stoichiometry: 1.0
species: 749574
type: SpeciesReference

757175
stoichiometry: 1.0
species: 741705
type: SpeciesReference

034866
fast: false
notes: R_S2T4g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T4g equation: [g] : hs_pre11 + (2) paps --> (2) h + hs_pre12 + (2) pap
product: 793822
reversible: false
type: Reaction
reactant: 793786
product: 793798
reactant: 793774
product: 793810
is: ENSCAFG00000020234.2
name: uronyl 2-sulfotransferase, Golgi

801439
stoichiometry: 2.0
species: 726778
type: SpeciesReference

830361
stoichiometry: 1.0
species: 750610
type: SpeciesReference

836122
stoichiometry: 1.0
species: 731852
type: SpeciesReference

796260
stoichiometry: 1.0
species: 745375
type: SpeciesReference

849152
stoichiometry: 1.0
species: 743276
type: SpeciesReference

781921
stoichiometry: 1.0
species: 752386
type: SpeciesReference

038416
modifier: 829049
reactant: 828893
type: Reaction
reactant: 828869
modifier: 829037
modifier: 829025
is: http://identifiers.org/ec-code/2.6.1.21
modifier: 829085
is: http://identifiers.org/ec-code/2.6.1.5
modifier: 829097
modifier: 829073
modifier: 829061
reversible: false
product: 828917
modifier: 829001
modifier: 828989
reactant: 828881
is: http://identifiers.org/ec-code/2.6.1.3
product: 828941
reactant: 828857
modifier: 829013
reactant: 828905
is: ENSCAFG00000008357.2
is: http://identifiers.org/ec-code/2.6.1.1
fast: false
product: 828953
is: http://identifiers.org/ec-code/2.6.1.58
modifier: 828977
notes: R_EHGLAT2m subsystem: Arginine and Proline Metabolism R_EHGLAT2m equation: [m] : e4hglu + oaa --> 4h2oglt + asp-L R_TYRTAm subsystem: Tyrosine metabolism R_TYRTAm equation: [m] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1m subsystem: Phenylalanine metabolism R_PHETA1m equation: [m] : akg + phe-L <==> glu-L + phpyr R_LCYSTATm subsystem: Cysteine Metabolism R_LCYSTATm equation: [m] : Lcyst + akg <==> 3spyr + glu-L R_CYSTAm subsystem: Cysteine Metabolism R_CYSTAm equation: [m] : akg + cys-L <==> glu-L + mercppyr R_ASPTAm subsystem: Alanine and Aspartate Metabolism R_ASPTAm equation: [m] : akg + asp-L <==> glu-L + oaa R_EHGLATm subsystem: Arginine and Proline Metabolism R_EHGLATm equation: [m] : akg + e4hglu --> 4h2oglt + glu-L R_3SALATAim subsystem: Cysteine Metabolism R_3SALATAim equation: [m] : 3sala + akg + h --> 3snpyr + glu-L
modifier: 828965
product: 828929

819160
stoichiometry: 2.0
species: 741151
type: SpeciesReference

742684
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Iduronate_C6H9O7
type: Species

811288
stoichiometry: 5.0
species: 751082
type: SpeciesReference

804611
stoichiometry: 1.0
species: 733822
type: SpeciesReference

771348
stoichiometry: 1.0
species: 749200
type: SpeciesReference

760599
stoichiometry: 1.0
species: 744423
type: SpeciesReference

807627
stoichiometry: 14.0
species: 747050
type: SpeciesReference

755719
stoichiometry: 1.0
species: 752337
type: SpeciesReference

738726
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Lacto-N-fucopentaosyl III ceramide_C50H89N2O26FULLRCO
type: Species

756581
stoichiometry: 1.0
species: 737858
type: SpeciesReference

778832
stoichiometry: 5.0
species: 741259
type: SpeciesReference

826049
stoichiometry: 1.0
species: 727795
type: SpeciesReference

842984
stoichiometry: 2.0
species: 746364
type: SpeciesReference

816873
stoichiometry: 1.0
species: 730922
type: SpeciesReference

849212
stoichiometry: 1.0
species: 743576
type: SpeciesReference

038343
is: ENSCAFG00000018766.2
reversible: false
notes: R_Htm subsystem: Transport, Mitochondrial R_Htm equation: h[c] --> h[m]
is: ENSCAFG00000005559.2
product: 828278
reactant: 828266
name: Uncoupling protein
is: ENSCAFG00000005564.2
fast: false
is: ENSCAFG00000002029.2
type: Reaction
is: ENSCAFG00000003684.2

761695
stoichiometry: 1.0
species: 746146
type: SpeciesReference

839871
stoichiometry: 1.0
species: 745663
type: SpeciesReference

777348
stoichiometry: 1.0
species: 741151
type: SpeciesReference

742067
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 16_C49H72N2O54S4
type: Species

735059
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate precursor (GalNAc-GlcA-(Gal)2-Xyl-L-Ser (protein))_C31H49NO25X
type: Species

741512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hexadecanoate (n-C16:0)_C16H31O2
type: Species

851213
stoichiometry: 1.0
species: 741332
type: SpeciesReference

837267
stoichiometry: 1.0
species: 731840
type: SpeciesReference

838741
stoichiometry: 1.0
species: 737436
type: SpeciesReference

836810
stoichiometry: 4.0
species: 733738
type: SpeciesReference

740132
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glyoxylate_C2H1O3
type: Species

837964
stoichiometry: 2.0
species: 753543
type: SpeciesReference

726416
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _12 hydroxy arachidonic acid_C20H31O3
type: Species

823696
stoichiometry: 6.0
species: 741416
type: SpeciesReference

729738
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S
type: Species

790798
stoichiometry: 1.0
species: 743060
type: SpeciesReference

786605
stoichiometry: 1.0
species: 750586
type: SpeciesReference

777458
stoichiometry: 1.0
species: 750381
type: SpeciesReference

035576
reactant: 801415
product: 801524
product: 801512
reactant: 801355
product: 801488
is: ENSCAFG00000003217.2
fast: false
product: 801439
is: http://identifiers.org/ec-code/1.11.1.8
product: 801451
notes: R_IDHPOXOXb subsystem: Tyrosine metabolism R_IDHPOXOXb equation: [c] : iodine + tyr-L --> 3ityr-L + h + i R_IDHPOXOX2b subsystem: Tyrosine metabolism R_IDHPOXOX2b equation: [c] : 3ityr-L + iodine --> 35diotyr + h + i R_IDHPOXOX3 subsystem: Tyrosine metabolism R_IDHPOXOX3 equation: [c] : 35diotyr + 3ityr-L + h2o2 --> 2amac + (2) h2o + triodthy R_IDHPOXOX4 subsystem: Tyrosine metabolism R_IDHPOXOX4 equation: [c] : (2) 35diotyr + h2o2 --> 2amac + (2) h2o + thyox-L R_THYPX subsystem: Tyrosine metabolism R_THYPX equation: [c] : (2) h + h2o2 + (2) i --> (2) h2o + iodine
reactant: 801403
reactant: 801391
product: 801427
reactant: 801379
type: Reaction
reactant: 801342
product: 801475
product: 801463
product: 801500
reactant: 801367
reversible: false

830385
stoichiometry: 1.0
species: 745339
type: SpeciesReference

846185
stoichiometry: 2.0
species: 747698
type: SpeciesReference

806641
stoichiometry: 1.0
species: 749442
type: SpeciesReference

039539
reactant: 838765
product: 838789
reactant: 838753
name: Hydrolase Class ( RXN R02973)
type: Reaction
reversible: false
product: 838777
is: ENSCAFG00000000188.2
is: ENSCAFG00000023591.1
notes: R_PNTEH subsystem: CoA Catabolism R_PNTEH equation: [c] : h2o + ptth --> cysam + pnto-R
fast: false

788589
stoichiometry: 1.0
species: 735865
type: SpeciesReference

802458
stoichiometry: 1.0
species: 731164
type: SpeciesReference

747528
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Normetanephrine_C9H14NO3
type: Species

738159
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Formaldehyde_CH2O
type: Species

781396
stoichiometry: 1.0
species: 731755
type: SpeciesReference

802398
stoichiometry: 1.0
species: 747379
type: SpeciesReference

772713
stoichiometry: 7.0
species: 747698
type: SpeciesReference

825784
stoichiometry: 1.0
species: 739135
type: SpeciesReference

822177
stoichiometry: 1.0
species: 743781
type: SpeciesReference

815690
stoichiometry: 5.0
species: 753157
type: SpeciesReference

743192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 16_C160H258N11O137S7
type: Species

759184
stoichiometry: 1.0
species: 726560
type: SpeciesReference

831872
stoichiometry: 2.0
species: 741235
type: SpeciesReference

854315
stoichiometry: 1.0
species: 732537
type: SpeciesReference

033632
reactant: 782787
fast: false
product: 782823
reactant: 782799
is: http://identifiers.org/ec-code/3.1.3.36
name: phosphatidylinositol-4,5-bisphosphate 5-phosphatase
is: ENSCAFG00000018690.2
product: 782811
type: Reaction
notes: R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi
reversible: false

754826
stoichiometry: 2.0
species: 729979
type: SpeciesReference

031331
reactant: 762361
product: 762434
product: 762446
notes: R_STS2 subsystem: Steroid Metabolism R_STS2 equation: [c] : estrones + h2o --> estrone + h + so4 R_STS3 subsystem: Steroid Metabolism R_STS3 equation: [c] : chsterols + h2o --> chsterol + h + so4 R_STS4 subsystem: Steroid Metabolism R_STS4 equation: [c] : h2o + prgnlones --> h + prgnlone + so4 R_STS3r subsystem: Steroid Metabolism R_STS3r equation: [r] : chsterols + h2o --> chsterol + h + so4 R_STS4r subsystem: Steroid Metabolism R_STS4r equation: [r] : h2o + prgnlones --> h + prgnlone + so4 R_STS1r subsystem: Steroid Metabolism R_STS1r equation: [r] : dheas + h2o --> dhea + h + so4 R_STS1 subsystem: Steroid Metabolism R_STS1 equation: [c] : dheas + h2o --> dhea + h + so4 R_STS2r subsystem: Steroid Metabolism R_STS2r equation: [r] : estrones + h2o --> estrone + h + so4
reactant: 762349
is: http://identifiers.org/ec-code/3.1.6.2
reactant: 762289
product: 762494
product: 762506
reactant: 762337
reactant: 762301
product: 762385
type: Reaction
fast: false
reactant: 762325
product: 762470
product: 762397
reactant: 762313
reactant: 762264
product: 762482
product: 762458
product: 762422
reactant: 762276
reactant: 762252
product: 762373
product: 762410
reversible: false
is: ENSCAFG00000011287.2

807411
stoichiometry: 1.0
species: 739790
type: SpeciesReference

846342
stoichiometry: 1.0
species: 747050
type: SpeciesReference

799991
stoichiometry: 1.0
species: 727771
type: SpeciesReference

782763
stoichiometry: 1.0
species: 736971
type: SpeciesReference

842206
stoichiometry: 1.0
species: 741259
type: SpeciesReference

854195
stoichiometry: 1.0
species: 736983
type: SpeciesReference

831462
stoichiometry: 1.0
species: 739631
type: SpeciesReference

758254
stoichiometry: 1.0
species: 731429
type: SpeciesReference

814444
stoichiometry: 1.0
species: 732056
type: SpeciesReference

847993
stoichiometry: 2.0
species: 735673
type: SpeciesReference

834349
stoichiometry: 1.0
species: 744598
type: SpeciesReference

819052
stoichiometry: 1.0
species: 730982
type: SpeciesReference

753882
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Xanthine_C5H4N4O2
type: Species

774157
stoichiometry: 1.0
species: 733933
type: SpeciesReference

835425
stoichiometry: 1.0
species: 744471
type: SpeciesReference

761549
stoichiometry: 1.0
species: 750478
type: SpeciesReference

783860
stoichiometry: 2.0
species: 745976
type: SpeciesReference

763804
stoichiometry: 1.0
species: 749200
type: SpeciesReference

838037
stoichiometry: 1.0
species: 732441
type: SpeciesReference

754416
stoichiometry: 2.0
species: 740229
type: SpeciesReference

733009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Calcium_Ca
type: Species

031765
product: 766654
product: 766678
reactant: 766618
product: 766690
reactant: 766630
type: Reaction
is: ENSCAFG00000005466.2
product: 766702
fast: false
reversible: false
is: http://identifiers.org/ec-code/3.7.1.3
reactant: 766642
notes: R_HKYNH subsystem: Tryptophan metabolism R_HKYNH equation: [c] : h2o + hLkynr --> 3hanthrn + ala-L R_LFORKYNHYD subsystem: Tryptophan metabolism R_LFORKYNHYD equation: [c] : Lfmkynr + h2o --> ala-L + h + nformanth R_KYN subsystem: Tryptophan metabolism R_KYN equation: [c] : Lkynr + h2o --> ala-L + anth + h
product: 766666
reactant: 766606

843806
stoichiometry: 1.0
species: 743914
type: SpeciesReference

798054
stoichiometry: 1.0
species: 741923
type: SpeciesReference

032438
reactant: 773039
fast: false
product: 773063
reactant: 773015
product: 773051
reactant: 773027
product: 773075
notes: R_FRUt1r subsystem: Transport, Extracellular R_FRUt1r equation: fru[e] <==> fru[c] R_GALt1r subsystem: Transport, Extracellular R_GALt1r equation: gal[e] <==> gal[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]
reversible: true
is: ENSCAFG00000020140.2
type: Reaction

757844
stoichiometry: 1.0
species: 741151
type: SpeciesReference

832544
stoichiometry: 1.0
species: 733286
type: SpeciesReference

784719
stoichiometry: 2.0
species: 741259
type: SpeciesReference

749695
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Pregnenolone_C21H32O2
type: Species

768975
stoichiometry: 1.0
species: 736255
type: SpeciesReference

033076
product: 778409
reactant: 778396
notes: R_MAN6PI subsystem: Fructose and Mannose Metabolism R_MAN6PI equation: [c] : man6p <==> f6p
is: ENSCAFG00000017973.2
is: http://identifiers.org/ec-code/5.3.1.8
fast: false
reversible: true
name: mannose-6-phosphate isomerase
type: Reaction

829145
stoichiometry: 1.0
species: 741271
type: SpeciesReference

034083
product: 786196
reactant: 786184
notes: R_5MTHFt subsystem: Transport, Extracellular R_5MTHFt equation: _5mthf[e] <==> 5mthf[c]
is: ENSCAFG00000005777.2
fast: false
reversible: true
name: _5-Methyltetrahydrofolate transport via receptor binding and protolysis
type: Reaction

774005
stoichiometry: 1.0
species: 741187
type: SpeciesReference

732176
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: arachidonic acid_C20H31O2
type: Species

810435
stoichiometry: 2.0
species: 746930
type: SpeciesReference

786232
stoichiometry: 1.0
species: 729380
type: SpeciesReference

751965
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosahexaenoic acid, n-3_C24H35O2
type: Species

782174
stoichiometry: 1.0
species: 754355
type: SpeciesReference

853686
stoichiometry: 1.0
species: 753266
type: SpeciesReference

744000
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 36_C247H394N17O210S11X
type: Species

763125
stoichiometry: 2.0
species: 727142
type: SpeciesReference

744832
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Leukotriene A4_C20H29O3
type: Species

761477
stoichiometry: 1.0
species: 741163
type: SpeciesReference

800654
stoichiometry: 1.0
species: 742904
type: SpeciesReference

803956
stoichiometry: 1.0
species: 746593
type: SpeciesReference

837688
stoichiometry: 1.0
species: 742904
type: SpeciesReference

807881
stoichiometry: 1.0
species: 733555
type: SpeciesReference

737496
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ecgonine_C9H14NO3
type: Species

749767
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: pristanic acid_C19H37O2
type: Species

781108
stoichiometry: 1.0
species: 729429
type: SpeciesReference

040043
type: Reaction
is: ENSCAFG00000010279.2
reactant: 842614
reactant: 842578
product: 842712
product: 842651
reactant: 842566
product: 842675
reversible: false
reactant: 842639
fast: false
reactant: 842602
product: 842724
notes: R_P45017A4r subsystem: Steroid Metabolism R_P45017A4r equation: [r] : 17ahprgstrn + h + nadph + (0.5) o2 --> acald + andrstndn + h2o + nadp R_P45017A2r subsystem: Steroid Metabolism R_P45017A2r equation: [r] : 17ahprgnlone + h + nadph + (0.5) o2 --> acald + dhea + h2o + nadp R_P45017A1r subsystem: Steroid Metabolism R_P45017A1r equation: [r] : h + nadph + o2 + prgnlone --> 17ahprgnlone + h2o + nadp R_P45017A3r subsystem: Steroid Metabolism R_P45017A3r equation: [r] : h + nadph + o2 + prgstrn --> 17ahprgstrn + h2o + nadp
reactant: 842590
product: 842663
is: http://identifiers.org/ec-code/1.14.99.9
product: 842700
reactant: 842626
product: 842687

810748
stoichiometry: 1.0
species: 726754
type: SpeciesReference

769494
stoichiometry: 1.0
species: 729714
type: SpeciesReference

771190
stoichiometry: 2.0
species: 741151
type: SpeciesReference

816596
stoichiometry: 1.0
species: 740241
type: SpeciesReference

782787
stoichiometry: 1.0
species: 748507
type: SpeciesReference

031559
is: ENSCAFG00000011581.2
type: Reaction
reactant: 764396
reactant: 764372
reversible: false
product: 764432
fast: false
is: ENSCAFG00000017056.2
reactant: 764384
product: 764420
product: 764408
notes: R_DOLPMT_L subsystem: N-Glycan Biosynthesis R_DOLPMT_L equation: [c] : (0.1) dolp_L + gdpmann --> (0.1) dolmanp_L + gdp R_DOLPMT_U subsystem: N-Glycan Biosynthesis R_DOLPMT_U equation: [c] : (0.1) dolp_U + gdpmann --> (0.1) dolmanp_U + gdp
is: http://identifiers.org/ec-code/2.4.1.83
is: ENSCAFG00000007404.2

737202
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dithiothreitol_C4H10O2S2
type: Species

735348
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Deoxyadenosine_C10H13N5O3
type: Species

784080
stoichiometry: 1.0
species: 742660
type: SpeciesReference

826736
stoichiometry: 1.0
species: 739003
type: SpeciesReference

756236
stoichiometry: 1.0
species: 733594
type: SpeciesReference

739656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GDP_C10H12N5O11P2
type: Species

765131
stoichiometry: 1.0
species: 733678
type: SpeciesReference

837796
stoichiometry: 2.0
species: 730922
type: SpeciesReference

824954
stoichiometry: 1.0
species: 732224
type: SpeciesReference

040633
is: http://identifiers.org/ec-code/1.1.1.21
product: 850695
type: Reaction
product: 850659
product: 850671
reactant: 850586
reactant: 850550
fast: false
product: 850646
reactant: 850634
reactant: 850574
reactant: 850610
product: 850719
product: 850707
reactant: 850598
is: ENSCAFG00000015181.2
reversible: false
reactant: 850562
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_LALDO2x subsystem: Pyruvate Metabolism R_LALDO2x equation: [c] : h + mthgxl + nadh --> lald-D + nad R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_PPDOx subsystem: Pyruvate Metabolism R_PPDOx equation: [c] : h + lald-D + nadh --> 12ppd-R + nad R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
product: 850683
product: 850731
reactant: 850622

746255
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Mercaptopyruvate_C3H3O3S
type: Species

781252
stoichiometry: 1.0
species: 738341
type: SpeciesReference

730910
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Adenosylcobalamin_C72H100CoN18O17P
type: Species

849429
stoichiometry: 2.0
species: 743600
type: SpeciesReference

812517
stoichiometry: 3.0
species: 741271
type: SpeciesReference

779435
stoichiometry: 1.0
species: 740023
type: SpeciesReference

039731
type: Reaction
product: 840327
reactant: 840303
fast: false
product: 840339
notes: R_GMPR subsystem: Nucleotides R_GMPR equation: [c] : gmp + (2) h + nadph --> imp + nadp + nh4
product: 840351
name: GMP reductase
reactant: 840315
is: ENSCAFG00000012127.2
is: http://identifiers.org/ec-code/1.7.1.7
is: ENSCAFG00000009920.2
reactant: 840291
reversible: false

814552
stoichiometry: 1.0
species: 726428
type: SpeciesReference

787844
stoichiometry: 1.0
species: 746303
type: SpeciesReference

788024
stoichiometry: 6.0
species: 741259
type: SpeciesReference

039140
type: Reaction
product: 834823
reversible: false
modifier: 834931
product: 834883
product: 834871
product: 834859
is: http://identifiers.org/ec-code/1.1.1.21
is: http://identifiers.org/ec-code/1.1.1.2
reactant: 834751
modifier: 834967
product: 834907
is: ENSCAFG00000017066.2
product: 834895
reactant: 834763
product: 834847
reactant: 834739
reactant: 834727
reactant: 834715
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_ALCD2yf subsystem: Glycolysis/Gluconeogenesis R_ALCD2yf equation: [c] : etoh + nadp --> acald + h + nadph R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_GALOR subsystem: Galactose metabolism R_GALOR equation: [c] : gal + h + nadph <==> galt + nadp R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
modifier: 834979
reactant: 834775
fast: false
product: 834811
modifier: 834955
modifier: 834943
reactant: 834799
reactant: 834787
product: 834919
product: 834835
reactant: 834703

785163
stoichiometry: 1.0
species: 734890
type: SpeciesReference

758556
stoichiometry: 1.0
species: 749406
type: SpeciesReference

776188
stoichiometry: 1.0
species: 734927
type: SpeciesReference

815497
stoichiometry: 1.0
species: 738474
type: SpeciesReference

849574
stoichiometry: 2.0
species: 734683
type: SpeciesReference

799798
stoichiometry: 1.0
species: 750854
type: SpeciesReference

760370
stoichiometry: 1.0
species: 732441
type: SpeciesReference

827401
stoichiometry: 3.0
species: 735409
type: SpeciesReference

035696
fast: false
reversible: false
product: 802337
reactant: 802313
name: phosphopantothenoylcysteine decarboxylase
reactant: 802325
is: ENSCAFG00000017983.2
product: 802349
type: Reaction
notes: R_PPCDC subsystem: CoA Biosynthesis R_PPCDC equation: [c] : 4ppcys + h --> co2 + pan4p
is: http://identifiers.org/ec-code/4.1.1.36

812251
stoichiometry: 1.0
species: 748591
type: SpeciesReference

783232
stoichiometry: 1.0
species: 749972
type: SpeciesReference

751263
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sphinganine 1-phosphate_C18H39NO5P
type: Species

851581
stoichiometry: 1.0
species: 741247
type: SpeciesReference

809531
stoichiometry: 1.0
species: 735745
type: SpeciesReference

753266
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UDPglucose_C15H22N2O17P2
type: Species

729622
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total 3 Coenzyme A_CO2FULLR3C21H31N7O15P3S
type: Species

842314
stoichiometry: 1.0
species: 747442
type: SpeciesReference

732284
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Arginine_C6H15N4O2
type: Species

731152
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Adrenyl carnitine_C29H49NO4
type: Species

792871
stoichiometry: 2.0
species: 733933
type: SpeciesReference

041130
is: ENSCAFG00000009182.2
product: 854857
type: Reaction
reactant: 854833
reactant: 854845
notes: R_CPPPGO subsystem: Heme Biosynthesis R_CPPPGO equation: [c] : cpppg3 + (2) h + o2 --> (2) co2 + (2) h2o + pppg9
product: 854881
fast: false
reactant: 854821
is: http://identifiers.org/ec-code/1.3.3.3
name: coproporphyrinogen oxidase (O2 required)
product: 854869
reversible: false

776612
stoichiometry: 1.0
species: 751663
type: SpeciesReference

742467
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 8_C79H116N4O64X
type: Species

031053
type: Reaction
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_MI145PP subsystem: Inositol Phosphate Metabolism R_MI145PP equation: [c] : h2o + mi145p --> mi14p + pi R_MI1345PP subsystem: Inositol Phosphate Metabolism R_MI1345PP equation: [c] : h2o + mi1345p --> mi134p + pi
reactant: 760018
is: http://identifiers.org/ec-code/3.1.3.56
reactant: 760042
product: 760090
product: 760066
reactant: 760054
reactant: 760030
product: 760102
product: 760078
is: ENSCAFG00000005743.2
is: ENSCAFG00000011650.2
is: ENSCAFG00000011136.2
is: ENSCAFG00000012969.2
fast: false
reversible: false

733798
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: clupanodonyl CoA_C43H64N7O17P3S
type: Species

786340
stoichiometry: 3.0
species: 747209
type: SpeciesReference

753991
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al_C27H46O3
type: Species

838638
stoichiometry: 1.0
species: 750405
type: SpeciesReference

736716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _4,8 dimethylnonanoyl carnitine_C18H37NO4
type: Species

848053
stoichiometry: 1.0
species: 732937
type: SpeciesReference

750586
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-11-retinol_C20H30O
type: Species

770594
stoichiometry: 1.0
species: 730765
type: SpeciesReference

829253
stoichiometry: 1.0
species: 747148
type: SpeciesReference

031873
notes: R_DOLPMT1_Uer subsystem: N-Glycan Biosynthesis R_DOLPMT1_Uer equation: [r] : (0.1) dolmanp_U + (0.1) m4mpdol_U --> (0.1) dolp_U + h + (0.1) m5mpdol_U R_DOLPMT1_Ler subsystem: N-Glycan Biosynthesis R_DOLPMT1_Ler equation: [r] : (0.1) dolmanp_L + (0.1) m4mpdol_L --> (0.1) dolp_L + h + (0.1) m5mpdol_L
reactant: 767424
type: Reaction
product: 767474
reactant: 767436
is: ENSCAFG00000012444.2
fast: false
product: 767486
reactant: 767400
product: 767498
product: 767448
is: http://identifiers.org/ec-code/2.4.1.130
product: 767460
reactant: 767412
reversible: false

744989
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: lignoceryl carnitine_C31H61NO4
type: Species

777792
stoichiometry: 1.0
species: 739184
type: SpeciesReference

851363
stoichiometry: 1.0
species: 740132
type: SpeciesReference

773391
stoichiometry: 2.0
species: 741308
type: SpeciesReference

034192
product: 787808
type: Reaction
reactant: 787736
notes: R_THYOXt subsystem: Transport, Extracellular R_THYOXt equation: hco3[c] + thyox-L[e] <==> hco3[e] + thyox-L[c] R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_TRIODTHYt subsystem: Transport, Extracellular R_TRIODTHYt equation: hco3[c] + triodthy[e] <==> hco3[e] + triodthy[c] R_ESTRADIOLGLCt subsystem: Transport, Extracellular R_ESTRADIOLGLCt equation: estradiolglc[e] + hco3[c] <==> estradiolglc[c] + hco3[e]
reactant: 787711
fast: false
reversible: true
reactant: 787760
reactant: 787748
product: 787772
is: ENSCAFG00000024024.1
is: ENSCAFG00000012377.2
product: 787820
reactant: 787723
product: 787796
product: 787784

853795
stoichiometry: 1.0
species: 748711
type: SpeciesReference

846767
stoichiometry: 1.0
species: 743312
type: SpeciesReference

800931
stoichiometry: 1.0
species: 732513
type: SpeciesReference

773207
stoichiometry: 1.0
species: 729513
type: SpeciesReference

748387
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2
type: Species

031114
product: 760647
is: ENSCAFG00000009385.2
reactant: 760611
fast: false
product: 760683
reactant: 760623
reversible: false
product: 760671
product: 760659
reactant: 760599
reactant: 760635
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap
type: Reaction
product: 760695

826844
stoichiometry: 3.0
species: 741163
type: SpeciesReference

832653
stoichiometry: 1.0
species: 730681
type: SpeciesReference

852604
stoichiometry: 2.0
species: 747002
type: SpeciesReference

778710
stoichiometry: 1.0
species: 751530
type: SpeciesReference

806015
stoichiometry: 1.0
species: 741199
type: SpeciesReference

817126
stoichiometry: 1.0
species: 730367
type: SpeciesReference

031487
name: beta-galactoside alpha-2,6-sialyltransferase
product: 763864
notes: R_S26Tg subsystem: N-Glycan Biosynthesis R_S26Tg equation: [g] : (2) cmpacna + l2fn2m2masn --> (2) cmp + (2) h + s2l2fn2m2masn
is: http://identifiers.org/ec-code/2.4.99.1
reversible: false
type: Reaction
fast: false
product: 763876
reactant: 763852
product: 763888
reactant: 763840
is: ENSCAFG00000013698.2

749984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin E1_C20H33O5
type: Species

747221
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3
type: Species

757953
stoichiometry: 2.0
species: 751651
type: SpeciesReference

754934
stoichiometry: 27.0
species: 741259
type: SpeciesReference

746146
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2
type: Species

740301
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-Glycerate_C3H5O4
type: Species

764214
stoichiometry: 1.0
species: 738329
type: SpeciesReference

782282
stoichiometry: 1.0
species: 741235
type: SpeciesReference

798824
stoichiometry: 8.0
species: 737103
type: SpeciesReference

836014
stoichiometry: 1.0
species: 741320
type: SpeciesReference

853097
stoichiometry: 1.0
species: 750878
type: SpeciesReference

739547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GD1a (homo sapiens)_C66H111N4O38FULLRCO
type: Species

754135
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7-alpha,24(S)-Dihydroxycholesterol_C27H46O3
type: Species

823430
stoichiometry: 3.0
species: 732477
type: SpeciesReference

788794
stoichiometry: 1.0
species: 740361
type: SpeciesReference

809762
stoichiometry: 1.0
species: 729416
type: SpeciesReference

778083
stoichiometry: 1.0
species: 754207
type: SpeciesReference

787736
stoichiometry: 1.0
species: 752803
type: SpeciesReference

780157
stoichiometry: 1.0
species: 732841
type: SpeciesReference

848269
stoichiometry: 3.0
species: 741235
type: SpeciesReference

788132
stoichiometry: 2.0
species: 741308
type: SpeciesReference

785572
stoichiometry: 1.0
species: 751759
type: SpeciesReference

830083
stoichiometry: 1.0
species: 754220
type: SpeciesReference

778602
stoichiometry: 1.0
species: 729979
type: SpeciesReference

809688
stoichiometry: 2.0
species: 741259
type: SpeciesReference

040741
reactant: 851533
is: http://identifiers.org/ec-code/1.14.13.9
product: 851605
product: 851581
notes: R_KYN3OX subsystem: Tryptophan metabolism R_KYN3OX equation: [c] : Lkynr + h + nadph + o2 --> h2o + hLkynr + nadp
fast: false
product: 851593
is: ENSCAFG00000015726.2
reactant: 851545
name: kynurenine 3-monooxygenase
reversible: false
reactant: 851569
reactant: 851557
type: Reaction

771034
stoichiometry: 2.0
species: 733933
type: SpeciesReference

852532
stoichiometry: 2.0
species: 734054
type: SpeciesReference

761768
stoichiometry: 1.0
species: 751566
type: SpeciesReference

794792
stoichiometry: 1.0
species: 741320
type: SpeciesReference

751372
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

783123
stoichiometry: 2.0
species: 738292
type: SpeciesReference

799641
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species: 730922
type: SpeciesReference

756128
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species: 741163
type: SpeciesReference

809242
stoichiometry: 1.0
species: 742684
type: SpeciesReference

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stoichiometry: 3.0
species: 741259
type: SpeciesReference

792172
stoichiometry: 1.0
species: 742369
type: SpeciesReference

846609
stoichiometry: 3.0
species: 747698
type: SpeciesReference

755948
stoichiometry: 1.0
species: 731054
type: SpeciesReference

779724
stoichiometry: 1.0
species: 747890
type: SpeciesReference

769384
stoichiometry: 1.0
species: 750757
type: SpeciesReference

849900
stoichiometry: 2.0
species: 730076
type: SpeciesReference

838469
stoichiometry: 1.0
species: 729714
type: SpeciesReference

758775
stoichiometry: 1.0
species: 751856
type: SpeciesReference

811132
stoichiometry: 1.0
species: 741175
type: SpeciesReference

796152
stoichiometry: 1.0
species: 744024
type: SpeciesReference

813180
stoichiometry: 1.0
species: 747209
type: SpeciesReference

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stoichiometry: 1.0
species: 730233
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3
type: Species

845379
stoichiometry: 1.0
species: 740898
type: SpeciesReference

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stoichiometry: 1.0
species: 751227
type: SpeciesReference

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notes: R_S2T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T1g equation: [g] : cs_c,d,e_pre1 + paps --> cs_d_pre2 + h + pap R_S2T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T2g equation: [g] : cs_d_pre5 + paps --> cspg_d + h + pap R_S2T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T3g equation: [g] : cs_b_pre5 + paps --> cspg_b + h + pap
fast: false
reactant: 785139
product: 785223
reactant: 785151
product: 785187
product: 785211
type: Reaction
reversible: false
reactant: 785175
reactant: 785163
product: 785235
product: 785199
is: ENSCAFG00000000372.2

830633
stoichiometry: 1.0
species: 747294
type: SpeciesReference

855291
stoichiometry: 1.0
species: 732260
type: SpeciesReference

760163
stoichiometry: 1.0
species: 741259
type: SpeciesReference

827209
stoichiometry: 1.0
species: 733702
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: phosphoethanolaminyl-trimannosyl-glucosaminyl-acylphosphatidylinositol (H6')_C51H94N2O32P2FULLRCO2FULLR2CO2
type: Species

840641
stoichiometry: 1.0
species: 745158
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Core 6_C16H27N2O10X
type: Species

739292
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Gal-Gal-Gal-Gal-Gal-Glc-Cer (homo sapiens)_C54H96NO32FULLRCO
type: Species

806797
stoichiometry: 1.0
species: 751288
type: SpeciesReference

036845
type: Reaction
product: 812155
fast: false
notes: R_DHCR71r subsystem: Cholesterol Metabolism R_DHCR71r equation: [r] : ddsmsterol + h + nadph --> dsmsterol + nadp R_DHCR72r subsystem: Cholesterol Metabolism R_DHCR72r equation: [r] : 7dhchsterol + h + nadph --> chsterol + nadp
product: 812167
reactant: 812131
reactant: 812094
reactant: 812106
is: http://identifiers.org/ec-code/1.3.1.21
is: ENSCAFG00000010424.2
reversible: false
product: 812143
reactant: 812118

777132
stoichiometry: 1.0
species: 736983
type: SpeciesReference

811806
stoichiometry: 1.0
species: 729979
type: SpeciesReference

745639
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

752890
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: testosterone glucuronide_C25H36O8
type: Species

788373
stoichiometry: 2.0
species: 734283
type: SpeciesReference

853242
stoichiometry: 1.0
species: 732441
type: SpeciesReference

757639
stoichiometry: 4.0
species: 741332
type: SpeciesReference

844205
stoichiometry: 1.0
species: 743805
type: SpeciesReference

797542
stoichiometry: 1.0
species: 750104
type: SpeciesReference

040597
modifier: 850189
notes: R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_34DHPLACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHPLACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhpac + h2o + nadp <==> 34dhpha + (2) h + nadph R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_34DHXMANDACOX subsystem: Tyrosine metabolism R_34DHXMAND…
modifier: 850309
is: http://identifiers.org/ec-code/1.2.1.3
modifier: 850297
product: 850069
modifier: 850285
product: 850045
is: http://identifiers.org/ec-code/1.2.1.21
is: http://identifiers.org/ec-code/1.2.1.39
product: 850009
modifier: 850177
is: ENSCAFG00000018146.2
reactant: 849936
product: 850093
reactant: 849924
type: Reaction
product: 850057
reversible: false
product: 850117
product: 850033
modifier: 850273
reactant: 849888
reactant: 849948
modifier: 850261
is: http://identifiers.org/ec-code/1.2.1.5
reactant: 849876
modifier: 850165
reactant: 849985
modifier: 850237
reactant: 849912
reactant: 849973
reactant: 849864
modifier: 850213
reactant: 849840
product: 850105
modifier: 850153
reactant: 849960
product: 850141
modifier: 850225
is: http://identifiers.org/ec-code/1.2.1.4
modifier: 850201
product: 850081
modifier: 850249
product: 850021
product: 850129
reactant: 849900
fast: false
reactant: 849852
product: 849997

762313
stoichiometry: 4.0
species: 741151
type: SpeciesReference

806929
stoichiometry: 1.0
species: 747710
type: SpeciesReference

803098
stoichiometry: 1.0
species: 749887
type: SpeciesReference

851153
stoichiometry: 2.0
species: 738292
type: SpeciesReference

794019
stoichiometry: 1.0
species: 742892
type: SpeciesReference

768537
stoichiometry: 2.0
species: 741259
type: SpeciesReference

810856
stoichiometry: 1.0
species: 744585
type: SpeciesReference

798498
stoichiometry: 1.0
species: 752193
type: SpeciesReference

035469
notes: R_ADSL2 subsystem: IMP Biosynthesis R_ADSL2 equation: [c] : 25aics --> aicar + fum R_ADSL1 subsystem: Nucleotides R_ADSL1 equation: [c] : dcamp --> amp + fum
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product: 800738
type: Reaction
is: ENSCAFG00000001206.2
product: 800726
fast: false
reversible: false
reactant: 800690
is: http://identifiers.org/ec-code/4.3.2.2
reactant: 800702

793114
stoichiometry: 1.0
species: 745651
type: SpeciesReference

037472
notes: R_NDP8 subsystem: Nucleotides R_NDP8 equation: [c] : dudp + h2o --> dump + h + pi R_DTMPK subsystem: Nucleotides R_DTMPK equation: [c] : atp + dtmp <==> adp + dtdp
product: 818895
is: ENSCAFG00000013076.2
modifier: 818967
type: Reaction
modifier: 818943
fast: false
is: http://identifiers.org/ec-code/3.6.1.6
reactant: 818883
product: 818907
is: http://identifiers.org/ec-code/2.7.4.9
reversible: false
modifier: 818955
modifier: 818931
product: 818919
reactant: 818871

788649
stoichiometry: 1.0
species: 736983
type: SpeciesReference

756471
stoichiometry: 2.0
species: 747148
type: SpeciesReference

827149
stoichiometry: 1.0
species: 733969
type: SpeciesReference

750866
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sarcosine_C3H7NO2
type: Species

810327
stoichiometry: 1.0
species: 727771
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: omeprazole_C17H19N3O3S
type: Species

835930
stoichiometry: 1.0
species: 739401
type: SpeciesReference

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stoichiometry: 1.0
species: 734187
type: SpeciesReference

830789
stoichiometry: 1.0
species: 733359
type: SpeciesReference

810050
stoichiometry: 1.0
species: 746930
type: SpeciesReference

853350
stoichiometry: 1.0
species: 731803
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: nervonyl coenzyme A_C45H76N7O17P3S
type: Species

730343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Type IIIAb_C92H158N5O55FULLRCO
type: Species

778348
stoichiometry: 1.0
species: 746930
type: SpeciesReference

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stoichiometry: 1.0
species: 750249
type: SpeciesReference

742176
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 24_C31H50NO26
type: Species

817414
stoichiometry: 8.0
species: 747123
type: SpeciesReference

784827
stoichiometry: 4.0
species: 753157
type: SpeciesReference

805550
stoichiometry: 1.0
species: 727118
type: SpeciesReference

807736
stoichiometry: 1.0
species: 741259
type: SpeciesReference

826158
stoichiometry: 2.0
species: 749273
type: SpeciesReference

809879
stoichiometry: 1.0
species: 753109
type: SpeciesReference

823586
stoichiometry: 3.0
species: 735397
type: SpeciesReference

802289
stoichiometry: 1.0
species: 746641
type: SpeciesReference

813072
stoichiometry: 1.0
species: 741259
type: SpeciesReference

831739
stoichiometry: 1.0
species: 741271
type: SpeciesReference

850622
stoichiometry: 2.0
species: 747050
type: SpeciesReference

038634
is: ENSCAFG00000008859.2
reactant: 830494
reactant: 830470
reversible: false
is: http://identifiers.org/ec-code/1.15.1.1
product: 830544
product: 830519
product: 830531
reactant: 830458
product: 830557
product: 830506
reactant: 830446
type: Reaction
notes: R_SPODMn subsystem: ROS Detoxification R_SPODMn equation: [n] : (2) h + (2) o2s --> h2o2 + o2 R_SPODMx subsystem: ROS Detoxification R_SPODMx equation: [x] : (2) h + (2) o2s --> h2o2 + o2 R_SPODM subsystem: ROS Detoxification R_SPODM equation: [c] : (2) h + (2) o2s --> h2o2 + o2
product: 830570
fast: false
reactant: 830434
reactant: 830482

740762
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Guanosine_C10H13N5O5
type: Species

775101
stoichiometry: 1.0
species: 729186
type: SpeciesReference

794211
stoichiometry: 8.0
species: 748663
type: SpeciesReference

731573
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: L-Alanine_C3H7NO2
type: Species

731429
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Oxoglutarate_C5H4O5
type: Species

849368
stoichiometry: 2.0
species: 734828
type: SpeciesReference

772400
stoichiometry: 1.0
species: 743914
type: SpeciesReference

797445
stoichiometry: 1.0
species: 744072
type: SpeciesReference

751663
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Succinate_C4H4O4
type: Species

808073
stoichiometry: 1.0
species: 751202
type: SpeciesReference

846076
stoichiometry: 1.0
species: 729162
type: SpeciesReference

828736
stoichiometry: 1.0
species: 752581
type: SpeciesReference

841461
stoichiometry: 1.0
species: 728221
type: SpeciesReference

034589
is: http://identifiers.org/ec-code/2.7.7.3
product: 791798
reactant: 791762
fast: false
modifier: 791822
type: Reaction
notes: R_PTPAT subsystem: CoA Biosynthesis R_PTPAT equation: [c] : atp + h + pan4p <==> dpcoa + ppi R_DPCOAK subsystem: CoA Biosynthesis R_DPCOAK equation: [c] : atp + dpcoa --> adp + coa + h
modifier: 791810
product: 791774
reversible: false
product: 791786
modifier: 791847
is: http://identifiers.org/ec-code/2.7.1.24
modifier: 791835
is: ENSCAFG00000014948.2
reactant: 791750
modifier: 791859

822815
stoichiometry: 1.0
species: 741259
type: SpeciesReference

032715
reversible: true
is: ENSCAFG00000011749.2
product: 775643
product: 775631
product: 775619
reactant: 775595
is: http://identifiers.org/ec-code/6.4.1.4
fast: false
is: ENSCAFG00000007887.2
name: methylcrotonoyl-CoA carboxylase, mitochondrial
type: Reaction
reactant: 775607
notes: R_MCCCrm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MCCCrm equation: [m] : 3mb2coa + atp + hco3 <==> 3mgcoa + adp + h + pi
reactant: 775583
product: 775655

777567
stoichiometry: 1.0
species: 748947
type: SpeciesReference

794646
stoichiometry: 1.0
species: 749116
type: SpeciesReference

736934
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10
type: Species

799425
stoichiometry: 16.0
species: 739827
type: SpeciesReference

764770
stoichiometry: 1.0
species: 742819
type: SpeciesReference

775679
stoichiometry: 1.0
species: 734151
type: SpeciesReference

809022
stoichiometry: 1.0
species: 745904
type: SpeciesReference

813216
stoichiometry: 1.0
species: 734417
type: SpeciesReference

033487
is: ENSCAFG00000003046.2
product: 781770
product: 781808
reactant: 781746
fast: false
reactant: 781722
type: Reaction
is: http://identifiers.org/ec-code/1.5.1.5
reactant: 781758
is: http://identifiers.org/ec-code/3.5.4.9
reversible: true
notes: R_MTHFD2 subsystem: Folate Metabolism R_MTHFD2 equation: [c] : mlthf + nad <==> methf + nadh R_MTHFC subsystem: Folate Metabolism R_MTHFC equation: [c] : h2o + methf <==> 10fthf + h
product: 781782
product: 781795
reactant: 781734

727807
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Sulfino-L-alanine_C3H5NO4S
type: Species

831270
stoichiometry: 1.0
species: 733884
type: SpeciesReference

753713
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: vaccenyl coenzyme A_C39H64N7O17P3S
type: Species

853916
stoichiometry: 4.0
species: 741259
type: SpeciesReference

790246
stoichiometry: 10.0
species: 732441
type: SpeciesReference

765488
stoichiometry: 1.0
species: 747553
type: SpeciesReference

733117
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Cob(I)alamin_C62H88CoN13O14P
type: Species

744121
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 3_C58H94N5O46S2X
type: Species

798607
stoichiometry: 7.0
species: 735481
type: SpeciesReference

776831
stoichiometry: 1.0
species: 733981
type: SpeciesReference

792727
stoichiometry: 1.0
species: 745531
type: SpeciesReference

801759
stoichiometry: 1.0
species: 733726
type: SpeciesReference

835713
stoichiometry: 1.0
species: 744290
type: SpeciesReference

791726
stoichiometry: 2.0
species: 740946
type: SpeciesReference

031270
reactant: 761573
product: 761659
fast: false
reversible: false
product: 761732
product: 761671
reactant: 761635
reactant: 761598
product: 761695
product: 761683
is: ENSCAFG00000002632.2
product: 761719
reactant: 761585
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6ET3er equation: [r] : m2emgacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs R_H4ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ET3er equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + em3gacpail_hs R_M4CET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4CET3er equation: [r] : m3emgacpail_hs + pe_hs --> dag_hs + mem2emgacpail_hs
product: 761707
reactant: 761610
reactant: 761647
type: Reaction
reactant: 761623

768600
stoichiometry: 2.0
species: 730922
type: SpeciesReference

830205
stoichiometry: 1.0
species: 734939
type: SpeciesReference

726729
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2,4 dihydroxy nitrophenol_C6H5NO4
type: Species

839425
stoichiometry: 2.0
species: 746930
type: SpeciesReference

825098
stoichiometry: 1.0
species: 733822
type: SpeciesReference

797229
stoichiometry: 1.0
species: 744484
type: SpeciesReference

841028
stoichiometry: 1.0
species: 753157
type: SpeciesReference

821004
stoichiometry: 1.0
species: 752854
type: SpeciesReference

808145
stoichiometry: 3.0
species: 731273
type: SpeciesReference

782066
stoichiometry: 1.0
species: 742309
type: SpeciesReference

747854
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Oxaloacetate_C4H2O5
type: Species

743444
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 34_C76H126N5O59S1
type: Species

810543
stoichiometry: 1.0
species: 747062
type: SpeciesReference

774882
stoichiometry: 1.0
species: 740059
type: SpeciesReference

824831
stoichiometry: 1.0
species: 741584
type: SpeciesReference

754355
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Zymostenol_C27H46O
type: Species

852965
stoichiometry: 1.0
species: 741151
type: SpeciesReference

827966
stoichiometry: 1.0
species: 735288
type: SpeciesReference

781674
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species: 733859
type: SpeciesReference

742819
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Imidazole-4-acetaldehyde_C5H6N2O
type: Species

827365
stoichiometry: 1.0
species: 748543
type: SpeciesReference

781517
stoichiometry: 1.0
species: 741259
type: SpeciesReference

738870
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species: 751094
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species: 753010
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species: 741308
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species: 728390
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species: 746786
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species: 728668
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species: 744637
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species: 741259
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initial concentration: NaN
initial amount: NaN
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type: Species

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species: 744650
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I, degradation product 8_C194H311N13O171S10
type: Species

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stoichiometry: 1.0
species: 738039
type: SpeciesReference

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stoichiometry: 3.0
species: 742976
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
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type: Species

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: O-Acetylcarnitine_C9H17NO4
type: Species

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species: 740530
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C54H90N3O40X
type: Species

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species: 732997
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hydroxymethylbilane_C40H38N4O17
type: Species

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species: 741356
type: SpeciesReference

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species: 739987
type: SpeciesReference

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stoichiometry: 2.0
species: 738582
type: SpeciesReference

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stoichiometry: 2.0
species: 748375
type: SpeciesReference

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species: 739631
type: SpeciesReference

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stoichiometry: 1.0
species: 731139
type: SpeciesReference

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species: 753991
type: SpeciesReference

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species: 736777
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: propionyl-carnitine_C10H19NO4
type: Species

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species: 729858
type: SpeciesReference

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species: 732805
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: mannosyl-glucosaminyl-acylphosphatidylinositiol (H2)_C37H68NO19PFULLRCO2FULLR2CO2
type: Species

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species: 744784
type: SpeciesReference

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stoichiometry: 1.0
species: 744916
type: SpeciesReference

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stoichiometry: 1.0
species: 739839
type: SpeciesReference

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species: 747173
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _1-alpha,25-Dihydroxyvitamin D3_C27H44O3
type: Species

820389
stoichiometry: 1.0
species: 736898
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Glucose_C6H12O6
type: Species

782487
stoichiometry: 1.0
species: 748687
type: SpeciesReference

847691
stoichiometry: 2.0
species: 731561
type: SpeciesReference

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stoichiometry: 6.0
species: 741199
type: SpeciesReference

763670
stoichiometry: 1.0
species: 751699
type: SpeciesReference

854364
stoichiometry: 1.0
species: 742660
type: SpeciesReference

729858
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Tn antigen_C8H14NO5X
type: Species

835183
stoichiometry: 1.0
species: 743841
type: SpeciesReference

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stoichiometry: 6.0
species: 741308
type: SpeciesReference

803351
stoichiometry: 1.0
species: 728728
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxykynurenine_C10H12N2O4
type: Species

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stoichiometry: 1.0
species: 745976
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _4-Methylzymosterol intermediate 2_C28H44O
type: Species

783704
stoichiometry: 1.0
species: 753206
type: SpeciesReference

815798
stoichiometry: 1.0
species: 748847
type: SpeciesReference

821763
stoichiometry: 1.0
species: 732441
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: UMP_C9H11N2O9P
type: Species

773547
stoichiometry: 1.0
species: 740409
type: SpeciesReference

745916
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Malate_C4H4O5
type: Species

847020
stoichiometry: 1.0
species: 742115
type: SpeciesReference

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reactant: 832040
product: 832076
fast: false
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product: 832100
reactant: 831980
product: 832052
reactant: 831992
type: Reaction
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product: 832088
reactant: 832016
reactant: 832028
product: 832112
product: 832064
reactant: 832004

855146
stoichiometry: 1.0
species: 730148
type: SpeciesReference

731996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Apocarboxylase (Lys residue)_C6H13N2OX
type: Species

847824
stoichiometry: 2.0
species: 752483
type: SpeciesReference

037255
is: ENSCAFG00000023755.1
is: ENSCAFG00000015541.2
reactant: 816270
notes: R_MAN1PT2 subsystem: Fructose and Mannose Metabolism R_MAN1PT2 equation: [c] : gdp + h + man1p --> gdpmann + pi
fast: false
product: 816306
is: http://identifiers.org/ec-code/2.7.7.22
reversible: false
reactant: 816294
name: mannose-1-phosphate guanylyltransferase (GDP)
product: 816318
type: Reaction
reactant: 816282

818665
stoichiometry: 1.0
species: 750357
type: SpeciesReference

854617
stoichiometry: 3.0
species: 731561
type: SpeciesReference

744546
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
type: Species

832977
stoichiometry: 1.0
species: 745579
type: SpeciesReference

831306
stoichiometry: 1.0
species: 753314
type: SpeciesReference

844675
stoichiometry: 1.0
species: 732865
type: SpeciesReference

759934
stoichiometry: 1.0
species: 753157
type: SpeciesReference

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stoichiometry: 1.0
species: 749079
type: SpeciesReference

793834
stoichiometry: 1.0
species: 750080
type: SpeciesReference

852123
stoichiometry: 1.0
species: 740530
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 5_C23H36O24S
type: Species

800484
stoichiometry: 1.0
species: 753700
type: SpeciesReference

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stoichiometry: 1.0
species: 727456
type: SpeciesReference

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stoichiometry: 3.0
species: 741259
type: SpeciesReference

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stoichiometry: 1.0
species: 749285
type: SpeciesReference

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stoichiometry: 1.0
species: 742236
type: SpeciesReference

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stoichiometry: 1.0
species: 728692
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
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type: Species

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species: 746930
type: SpeciesReference

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stoichiometry: 1.0
species: 745411
type: SpeciesReference

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species: 735216
type: SpeciesReference

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species: 742467
type: SpeciesReference

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stoichiometry: 1.0
species: 749996
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 6_C67H98N4O83S9
type: Species

780542
stoichiometry: 1.0
species: 752109
type: SpeciesReference

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stoichiometry: 1.0
species: 743048
type: SpeciesReference

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stoichiometry: 1.0
species: 744338
type: SpeciesReference

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stoichiometry: 2.0
species: 747209
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dATP_C10H12N5O12P3
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyinosine_C10H12N4O4
type: Species

789819
stoichiometry: 1.0
species: 749200
type: SpeciesReference

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stoichiometry: 1.0
species: 727275
type: SpeciesReference

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stoichiometry: 1.0
species: 739987
type: SpeciesReference

801161
stoichiometry: 1.0
species: 752938
type: SpeciesReference

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stoichiometry: 1.0
species: 726912
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Arachidic acid_C20H39O2
type: Species

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stoichiometry: 1.0
species: 734151
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoic acid, n-6_C24H37O2
type: Species

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stoichiometry: 1.0
species: 748663
type: SpeciesReference

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stoichiometry: 1.0
species: 748873
type: SpeciesReference

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is: ENSCAFG00000010369.2
is: http://identifiers.org/ec-code/4.1.1.19
product: 794876
reversible: false
notes: R_ARGDCm subsystem: Arginine and Proline Metabolism R_ARGDCm equation: [m] : arg-L + h --> agm + co2
type: Reaction
reactant: 794840
name: arginine decarboxylase (m)
fast: false
product: 794864
reactant: 794852
is: ENSCAFG00000011027.2

790102
stoichiometry: 1.0
species: 736874
type: SpeciesReference

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product: 842170
reactant: 842086
notes: R_PIACGT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_PIACGT equation: [c] : pail_hs + uacgam --> acgpail_hs + h + udp R_DOLPMT_L subsystem: N-Glycan Biosynthesis R_DOLPMT_L equation: [c] : (0.1) dolp_L + gdpmann --> (0.1) dolmanp_L + gdp R_DOLPMT_U subsystem: N-Glycan Biosynthesis R_DOLPMT_U equation: [c] : (0.1) dolp_U + gdpmann --> (0.1) dolmanp_U + gdp
reactant: 842134
reactant: 842098
product: 842206
is: http://identifiers.org/ec-code/2.4.1.198
product: 842182
reversible: false
product: 842146
reactant: 842110
reactant: 842122
product: 842194
fast: false
product: 842158
type: Reaction
is: ENSCAFG00000020095.2
is: http://identifiers.org/ec-code/2.4.1.83

751518
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: stearoylcarnitine_C25H49NO4
type: Species

803242
stoichiometry: 1.0
species: 741440
type: SpeciesReference

810964
stoichiometry: 1.0
species: 749249
type: SpeciesReference

815063
stoichiometry: 1.0
species: 735288
type: SpeciesReference

793942
stoichiometry: 2.0
species: 747722
type: SpeciesReference

852015
stoichiometry: 1.0
species: 750177
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: myo-Inositol hexakisphosphate_C6H6O24P6
type: Species

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stoichiometry: 7.0
species: 753399
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ubiquinone-10_C59H90O4
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Trimethylammoniobutanoate_C7H15NO2
type: Species

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stoichiometry: 8.0
species: 741271
type: SpeciesReference

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stoichiometry: 3.0
species: 739987
type: SpeciesReference

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stoichiometry: 3.0
species: 741332
type: SpeciesReference

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stoichiometry: 3.0
species: 746918
type: SpeciesReference

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stoichiometry: 1.0
species: 751687
type: SpeciesReference

777240
stoichiometry: 1.0
species: 749297
type: SpeciesReference

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stoichiometry: 1.0
species: 741199
type: SpeciesReference

766858
stoichiometry: 1.0
species: 748302
type: SpeciesReference

847582
stoichiometry: 1.0
species: 741259
type: SpeciesReference

767015
stoichiometry: 2.0
species: 747516
type: SpeciesReference

846004
stoichiometry: 1.0
species: 728944
type: SpeciesReference

816379
stoichiometry: 1.0
species: 740566
type: SpeciesReference

816656
stoichiometry: 1.0
species: 734501
type: SpeciesReference

773655
stoichiometry: 1.0
species: 751542
type: SpeciesReference

032931
is: ENSCAFG00000024836.1
is: ENSCAFG00000002831.2
is: ENSCAFG00000002836.2
product: 777324
fast: false
is: ENSCAFG00000025306.1
is: ENSCAFG00000024705.1
is: ENSCAFG00000025592.1
is: ENSCAFG00000014306.2
name: UDP-glucuronosyltransferase 1-10 precursor, microsomal
is: http://identifiers.org/ec-code/2.4.1.17
type: Reaction
reactant: 777300
notes: R_UGT1A8r subsystem: Steroid Metabolism R_UGT1A8r equation: [r] : estriol + udpglcur --> estriolglc + udp
is: ENSCAFG00000014300.2
reactant: 777312
is: ENSCAFG00000002857.2
product: 777336
reversible: false

794367
stoichiometry: 1.0
species: 741259
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Urea_CH4N2O
type: Species

741090
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Hydrogen peroxide_H2O2
type: Species

854472
stoichiometry: 1.0
species: 733981
type: SpeciesReference

780434
stoichiometry: 1.0
species: 732937
type: SpeciesReference

845668
stoichiometry: 1.0
species: 726149
type: SpeciesReference

731888
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: androsterone glucuronide_C25H38O8
type: Species

843298
stoichiometry: 1.0
species: 752483
type: SpeciesReference

835075
stoichiometry: 1.0
species: 753326
type: SpeciesReference

733467
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
type: Species

727239
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,5-Diiodo-L-tyrosine_C9H9I2NO3
type: Species

824687
stoichiometry: 1.0
species: 732092
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ITP_C10H11N4O14P3
type: Species

851653
stoichiometry: 1.0
species: 752890
type: SpeciesReference

736243
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dehydroascorbate_C6H6O6
type: Species

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stoichiometry: 1.0
species: 753639
type: SpeciesReference

763560
stoichiometry: 1.0
species: 735409
type: SpeciesReference

838313
stoichiometry: 3.0
species: 747209
type: SpeciesReference

791087
stoichiometry: 1.0
species: 752037
type: SpeciesReference

771493
stoichiometry: 1.0
species: 749490
type: SpeciesReference

774906
stoichiometry: 1.0
species: 741259
type: SpeciesReference

820497
stoichiometry: 1.0
species: 737151
type: SpeciesReference

030753
product: 757651
is: http://identifiers.org/ec-code/5.3.3.1
fast: false
product: 757589
type: Reaction
product: 757626
notes: R_C3STDH1r subsystem: Cholesterol Metabolism R_C3STDH1r equation: [r] : 4mzym_int1 + nad --> 4mzym_int2 + co2 + h + nadh R_C4STMO2Pr subsystem: Cholesterol Metabolism R_C4STMO2Pr equation: [r] : 4mzym_int2 + nadp + o2 --> co2 + h + nadph + zym_int2 R_C4STMO2r subsystem: Cholesterol Metabolism R_C4STMO2r equation: [r] : 4mzym_int2 + nad + o2 --> co2 + h + nadh + zym_int2 R_C3STDH1Pr subsystem: Cholesterol Metabolism R_C3STDH1Pr equation: [r] : 4mzym_int1 + nadp --> 4mzym_int2 + co2 + h + nadph
reactant: 757565
is: ENSCAFG00000019172.2
reactant: 757540
reactant: 757553
product: 757639
product: 757601
reversible: false
reactant: 757577
product: 757613
reactant: 757528

752325
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO
type: Species

825230
stoichiometry: 1.0
species: 752193
type: SpeciesReference

796988
stoichiometry: 1.0
species: 747185
type: SpeciesReference

849646
stoichiometry: 2.0
species: 753495
type: SpeciesReference

819498
stoichiometry: 1.0
species: 743528
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Glutamate 5-semialdehyde_C5H9NO3
type: Species

795898
stoichiometry: 1.0
species: 739196
type: SpeciesReference

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stoichiometry: 1.0
species: 747099
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: O2_O2
type: Species

834493
stoichiometry: 2.0
species: 747331
type: SpeciesReference

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stoichiometry: 1.0
species: 743624
type: SpeciesReference

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stoichiometry: 1.0
species: 745868
type: SpeciesReference

837628
stoichiometry: 1.0
species: 741392
type: SpeciesReference

834566
stoichiometry: 1.0
species: 729979
type: SpeciesReference

762907
stoichiometry: 1.0
species: 751082
type: SpeciesReference

751808
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Taurine_C2H7NO3S
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S
type: Species

757528
stoichiometry: 2.0
species: 747746
type: SpeciesReference

755080
stoichiometry: 1.0
species: 742139
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Citrate_C6H5O7
type: Species

774374
stoichiometry: 1.0
species: 728956
type: SpeciesReference

030645
reversible: false
reactant: 756333
product: 756357
reactant: 756321
name: _5'-methylthioadenosine phosphorylase
product: 756345
notes: R_MTAP subsystem: Arginine and Proline Metabolism R_MTAP equation: [c] : 5mta + pi --> 5mdr1p + ade
type: Reaction
fast: false
is: http://identifiers.org/ec-code/2.4.2.28
is: ENSCAFG00000001671.2

034432
product: 789747
reactant: 789735
notes: R_H2Otm subsystem: Transport, Mitochondrial R_H2Otm equation: h2o[c] <==> h2o[m]
is: ENSCAFG00000017480.2
fast: false
reversible: true
name: H2O transport, mitochondrial
type: Reaction

036953
reactant: 813240
notes: R_UDPGLDCg subsystem: Nucleotide Sugar Metabolism R_UDPGLDCg equation: [g] : h + udpglcur --> co2 + udpxyl
fast: false
reversible: false
product: 813276
is: ENSCAFG00000002096.2
product: 813264
type: Reaction
name: UDP-D-glucuronate decarboxylase, Golgi apparatus
reactant: 813252
is: http://identifiers.org/ec-code/4.1.1.35

854725
stoichiometry: 1.0
species: 741175
type: SpeciesReference

735276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cytidine_C9H13N3O5
type: Species

037906
product: 824010
product: 823962
fast: false
reactant: 823864
reactant: 823852
product: 823949
is: http://identifiers.org/ec-code/2.4.99.4
product: 823998
reversible: false
product: 823937
reactant: 823840
is: ENSCAFG00000020139.2
product: 823925
reactant: 823889
type: Reaction
product: 823986
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_ST3GAL21g subsystem: Sphingolipid Metabolism R_ST3GAL21g equation: [g] : cmpacna + ga1_hs --> cmp + gm1b_hs + h R_ST3GAL22g subsystem: Sphingolipid Metabolism R_ST3GAL22g equation: [g] : cmpacna + gm1_hs --> cmp + gd1a_hs + h R_SIAT4Bg subsystem: Sphingolipid Metabolism R_SIAT4Bg equation: [g] : cmpacna + galgbside_hs --> acngalgbside_hs + cmp + h R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1 R_ST3GAL23g subsystem: Sphingolipid Metabolism R_ST3GAL23g equation: [g] : cmpacna + gd1b_hs --> cmp + gt1b_hs + h
reactant: 823901
reactant: 823913
reactant: 823876
product: 823974

812106
stoichiometry: 1.0
species: 735853
type: SpeciesReference

809989
stoichiometry: 4.0
species: 749200
type: SpeciesReference

798908
stoichiometry: 6.0
species: 735385
type: SpeciesReference

795742
stoichiometry: 1.0
species: 744510
type: SpeciesReference

790582
stoichiometry: 1.0
species: 740970
type: SpeciesReference

750165
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2
type: Species

784935
stoichiometry: 1.0
species: 741259
type: SpeciesReference

819895
stoichiometry: 1.0
species: 739852
type: SpeciesReference

845075
stoichiometry: 1.0
species: 727636
type: SpeciesReference

783342
stoichiometry: 1.0
species: 751651
type: SpeciesReference

842614
stoichiometry: 1.0
species: 726536
type: SpeciesReference

845220
stoichiometry: 1.0
species: 739987
type: SpeciesReference

808385
stoichiometry: 1.0
species: 734127
type: SpeciesReference

816017
stoichiometry: 2.0
species: 741151
type: SpeciesReference

822394
stoichiometry: 1.0
species: 732308
type: SpeciesReference

832821
stoichiometry: 1.0
species: 741259
type: SpeciesReference

794912
stoichiometry: 1.0
species: 746497
type: SpeciesReference

848510
stoichiometry: 1.0
species: 745290
type: SpeciesReference

799305
stoichiometry: 1.0
species: 745399
type: SpeciesReference

774229
stoichiometry: 1.0
species: 744663
type: SpeciesReference

035359
product: 799871
product: 799907
reactant: 799859
product: 799895
reactant: 799810
reactant: 799847
reactant: 799786
fast: false
is: ENSCAFG00000003532.2
product: 799919
type: Reaction
product: 799943
reversible: false
product: 799883
reactant: 799798
reactant: 799834
is: http://identifiers.org/ec-code/1.5.1.8
notes: R_SACCD3m subsystem: Lysine Metabolism R_SACCD3m equation: [m] : akg + h + lys-L + nadph --> h2o + nadp + saccrp-L R_SACCD4m subsystem: Lysine Metabolism R_SACCD4m equation: [m] : h2o + nadp + saccrp-L --> L2aadp6sa + glu-L + h + nadph
reactant: 799822
product: 799931
is: http://identifiers.org/ec-code/1.5.1.10

777677
stoichiometry: 1.0
species: 733189
type: SpeciesReference

801052
stoichiometry: 1.0
species: 741151
type: SpeciesReference

762155
stoichiometry: 1.0
species: 734283
type: SpeciesReference

732805
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Butanoyl-CoA_C25H38N7O17P3S
type: Species

738051
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2
type: Species

038561
is: http://identifiers.org/ec-code/4.4.1.16
reactant: 829963
product: 829999
notes: R_SELCYSLY2 subsystem: Selenoamino acid metabolism R_SELCYSLY2 equation: [c] : pdx5p + selcys --> ala-L + h + pydx5p + seln R_SELCYSLY subsystem: Selenoamino acid metabolism R_SELCYSLY equation: [c] : dtt + selcys --> ala-L + dttOX + h + seln
reactant: 829950
product: 830011
product: 829987
is: ENSCAFG00000012370.2
product: 829975
type: Reaction
reversible: false
product: 830023
fast: false
reactant: 829938

763293
stoichiometry: 2.0
species: 747794
type: SpeciesReference

736668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2,6 dimethylheptanoyl-CoA_C30H52N7O17P3S
type: Species

804028
stoichiometry: 1.0
species: 740132
type: SpeciesReference

732671
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Bilirubin monoglucuronide_C39H44N4O12
type: Species

764372
stoichiometry: 1.0
species: 736959
type: SpeciesReference

833928
stoichiometry: 1.0
species: 738486
type: SpeciesReference

845932
stoichiometry: 18.0
species: 749249
type: SpeciesReference

834265
stoichiometry: 1.0
species: 729979
type: SpeciesReference

728607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Formiminotetrahydrofolate_C20H22N8O6
type: Species

777866
stoichiometry: 1.0
species: 738678
type: SpeciesReference

762844
stoichiometry: 1.0
species: 732332
type: SpeciesReference

826591
stoichiometry: 1.0
species: 729786
type: SpeciesReference

754572
stoichiometry: 1.0
species: 742152
type: SpeciesReference

733226
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CDPcholine_C14H25N4O11P2
type: Species

799160
stoichiometry: 1.0
species: 735011
type: SpeciesReference

753822
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: omega hydroxy dodecanoate (n-C12:0)_C12H23O3
type: Species

036095
reactant: 806569
reversible: true
is: ENSCAFG00000009395.2
product: 806605
is: ENSCAFG00000010574.2
type: Reaction
product: 806593
fast: false
reactant: 806581
product: 806617
notes: R_NRPPHRt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_NRPPHRt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + nrpphr[e] <==> (2) na1[c] + nrpphr[c] R_DOPAt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_DOPAt4_LPAREN_2_RPAREN_r equation: dopa[e] + (2) na1[e] <==> dopa[c] + (2) na1[c]
reactant: 806557

805105
stoichiometry: 1.0
species: 748133
type: SpeciesReference

792016
stoichiometry: 1.0
species: 748735
type: SpeciesReference

806124
stoichiometry: 1.0
species: 744676
type: SpeciesReference

829698
stoichiometry: 1.0
species: 747343
type: SpeciesReference

764661
stoichiometry: 1.0
species: 741259
type: SpeciesReference

782607
stoichiometry: 1.0
species: 741259
type: SpeciesReference

801867
stoichiometry: 1.0
species: 731900
type: SpeciesReference

813325
stoichiometry: 2.0
species: 753399
type: SpeciesReference

727979
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Aminobutanoate_C4H9NO2
type: Species

732513
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Crotonoyl-CoA_C25H36N7O17P3S
type: Species

744277
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 4_C53H86N4O38X
type: Species

774773
stoichiometry: 1.0
species: 740107
type: SpeciesReference

775522
stoichiometry: 1.0
species: 745543
type: SpeciesReference

791618
stoichiometry: 1.0
species: 735529
type: SpeciesReference

770257
stoichiometry: 1.0
species: 739135
type: SpeciesReference

726839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Decaprenyl-6-methoxyphenol_C57H88O2
type: Species

765596
stoichiometry: 4.0
species: 741259
type: SpeciesReference

838181
stoichiometry: 1.0
species: 744820
type: SpeciesReference

791353
stoichiometry: 2.0
species: 749322
type: SpeciesReference

790354
stoichiometry: 1.0
species: 742708
type: SpeciesReference

033330
product: 780025
reversible: true
is: http://identifiers.org/ec-code/4.2.1.3
is: ENSCAFG00000001766.2
type: Reaction
reactant: 780013
is: ENSCAFG00000001786.2
name: aconitase
notes: R_ACONT subsystem: Citric Acid Cycle R_ACONT equation: [c] : cit <==> icit
fast: false

750707
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: PA6_C90H145N6O65X
type: Species

809314
stoichiometry: 1.0
species: 742696
type: SpeciesReference

754632
stoichiometry: 1.0
species: 750345
type: SpeciesReference

753047
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tyramine_C8H12NO
type: Species

830909
stoichiometry: 1.0
species: 733630
type: SpeciesReference

855425
stoichiometry: 3.0
species: 747087
type: SpeciesReference

831162
stoichiometry: 1.0
species: 750998
type: SpeciesReference

032655
is: ENSCAFG00000020040.2
reactant: 774785
reversible: false
fast: false
name: glycogen debranching enzyme
is: http://identifiers.org/ec-code/3.2.1.33
notes: R_GLDBRAN subsystem: Starch and Sucrose Metabolism R_GLDBRAN equation: [c] : dxtrn + h2o --> glc-D + glygn3
type: Reaction
reactant: 774797
product: 774821
product: 774809

800376
stoichiometry: 1.0
species: 749297
type: SpeciesReference

839534
stoichiometry: 1.0
species: 726452
type: SpeciesReference

820594
stoichiometry: 1.0
species: 726368
type: SpeciesReference

804175
stoichiometry: 1.0
species: 741753
type: SpeciesReference

738594
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1_C64H112N3O35FULLRCO
type: Species

819739
stoichiometry: 1.0
species: 743456
type: SpeciesReference

037194
reversible: false
type: Reaction
is: ENSCAFG00000023464.1
name: Arachidonate 12-lipoxygenase R
is: http://identifiers.org/ec-code/1.13.11.31
fast: false
product: 815774
reactant: 815750
notes: R_ALOX12R subsystem: Eicosanoid Metabolism R_ALOX12R equation: [c] : arachd + o2 --> 12RHPET
reactant: 815762

729404
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetylserotonin_C12H14N2O2
type: Species

810651
stoichiometry: 2.0
species: 741151
type: SpeciesReference

821221
stoichiometry: 1.0
species: 728668
type: SpeciesReference

803664
stoichiometry: 1.0
species: 747148
type: SpeciesReference

785007
stoichiometry: 1.0
species: 727299
type: SpeciesReference

745796
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X
type: Species

797982
stoichiometry: 1.0
species: 750201
type: SpeciesReference

763996
stoichiometry: 1.0
species: 730052
type: SpeciesReference

842422
stoichiometry: 1.0
species: 750550
type: SpeciesReference

767231
stoichiometry: 1.0
species: 747074
type: SpeciesReference

771613
stoichiometry: 1.0
species: 727190
type: SpeciesReference

754789
stoichiometry: 1.0
species: 742660
type: SpeciesReference

783015
stoichiometry: 1.0
species: 730946
type: SpeciesReference

780001
stoichiometry: 1.0
species: 746918
type: SpeciesReference

749200
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phosphate_HO4P
type: Species

847716
stoichiometry: 6.0
species: 739926
type: SpeciesReference

735565
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dCDP_C9H12N3O10P2
type: Species

842763
stoichiometry: 1.0
species: 748591
type: SpeciesReference

787614
stoichiometry: 1.0
species: 730922
type: SpeciesReference

730645
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetylneuraminate_C11H18NO9
type: Species

753194
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: UDP_C9H11N2O12P2
type: Species

832328
stoichiometry: 1.0
species: 738991
type: SpeciesReference

835641
stoichiometry: 32.0
species: 741283
type: SpeciesReference

823153
stoichiometry: 1.0
species: 747002
type: SpeciesReference

797870
stoichiometry: 1.0
species: 752085
type: SpeciesReference

746473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3
type: Species

768758
stoichiometry: 1.0
species: 736486
type: SpeciesReference

817874
stoichiometry: 2.0
species: 741259
type: SpeciesReference

728486
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8
type: Species

841689
stoichiometry: 1.0
species: 730476
type: SpeciesReference

782330
stoichiometry: 1.0
species: 733503
type: SpeciesReference

804575
stoichiometry: 1.0
species: 737557
type: SpeciesReference

769276
stoichiometry: 1.0
species: 734345
type: SpeciesReference

771770
stoichiometry: 1.0
species: 752496
type: SpeciesReference

793582
stoichiometry: 4.0
species: 742696
type: SpeciesReference

733909
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: CMP_C9H12N3O8P
type: Species

765717
stoichiometry: 1.0
species: 729573
type: SpeciesReference

825916
stoichiometry: 1.0
species: 735481
type: SpeciesReference

827858
stoichiometry: 1.0
species: 751202
type: SpeciesReference

828098
stoichiometry: 1.0
species: 728426
type: SpeciesReference

798703
stoichiometry: 5.0
species: 735938
type: SpeciesReference

767486
stoichiometry: 1.0
species: 745615
type: SpeciesReference

752752
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Reduced thioredoxin_XH2
type: Species

824942
stoichiometry: 1.0
species: 731139
type: SpeciesReference

788673
stoichiometry: 1.0
species: 741151
type: SpeciesReference

031258
is: http://identifiers.org/ec-code/2.4.2.2
notes: R_PYNP2r subsystem: Pyrimidine Catabolism R_PYNP2r equation: [c] : pi + uri <==> r1p + ura
name: pyrimidine-nucleoside phosphorylase (uracil)
reactant: 761525
type: Reaction
reversible: true
is: ENSCAFG00000014262.2
product: 761549
reactant: 761537
product: 761561
fast: false

826724
stoichiometry: 1.0
species: 736111
type: SpeciesReference

784092
stoichiometry: 10.0
species: 741151
type: SpeciesReference

754318
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Xylulose_C5H10O5
type: Species

740736
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Geranyl diphosphate_C10H17O7P2
type: Species

747418
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: nifedipine_C17H18N2O6
type: Species

798198
stoichiometry: 1.0
species: 741621
type: SpeciesReference

782799
stoichiometry: 1.0
species: 741151
type: SpeciesReference

040031
name: _5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)
notes: R_OPAHir subsystem: Glutathione Metabolism R_OPAHir equation: [c] : 5oxpro + atp + (2) h2o --> adp + glu-L + h + pi
reactant: 842494
product: 842542
product: 842518
reactant: 842506
fast: false
is: http://identifiers.org/ec-code/3.5.2.9
reactant: 842482
reversible: false
is: ENSCAFG00000001500.2
product: 842530
product: 842554
type: Reaction

736971
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10
type: Species

810736
stoichiometry: 1.0
species: 742928
type: SpeciesReference

762191
stoichiometry: 1.0
species: 751348
type: SpeciesReference

807893
stoichiometry: 1.0
species: 751446
type: SpeciesReference

755804
stoichiometry: 1.0
species: 747050
type: SpeciesReference

816560
stoichiometry: 2.0
species: 730886
type: SpeciesReference

737484
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: hydroxylated ebastine_C32H39NO3
type: Species

753278
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UDPglucose_C15H22N2O17P2
type: Species

735901
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
type: Species

772134
stoichiometry: 1.0
species: 744084
type: SpeciesReference

850069
stoichiometry: 2.0
species: 748362
type: SpeciesReference

837652
stoichiometry: 4.0
species: 753133
type: SpeciesReference

737618
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (phosphoethanolaminyl-dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (H7)_C53H100N3O35P3FULLRCO2FULLR2CO2
type: Species

033778
product: 783728
reactant: 783716
notes: R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c]
is: ENSCAFG00000015013.2
fast: false
reversible: true
name: Urea transport via facilitate diffusion
type: Reaction

761889
stoichiometry: 4.0
species: 733981
type: SpeciesReference

812263
stoichiometry: 1.0
species: 753109
type: SpeciesReference

783244
stoichiometry: 1.0
species: 749948
type: SpeciesReference

751251
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Sulfate_O4S
type: Species

784418
stoichiometry: 3.0
species: 731164
type: SpeciesReference

758568
stoichiometry: 1.0
species: 730016
type: SpeciesReference

847130
stoichiometry: 1.0
species: 743324
type: SpeciesReference

799786
stoichiometry: 1.0
species: 741199
type: SpeciesReference

849562
stoichiometry: 2.0
species: 734927
type: SpeciesReference

738414
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine_C8H15N3O8P
type: Species

041166
reversible: false
product: 855231
notes: R_RBK subsystem: Pentose Phosphate Pathway R_RBK equation: [c] : atp + rib-D --> adp + h + r5p R_DRBK subsystem: Pentose Phosphate Pathway R_DRBK equation: [c] : atp + drib --> 2dr5p + adp + h
reactant: 855206
reactant: 855182
product: 855255
is: http://identifiers.org/ec-code/2.7.1.15
reactant: 855194
is: ENSCAFG00000005191.2
type: Reaction
fast: false
product: 855219
product: 855243

785151
stoichiometry: 3.0
species: 748687
type: SpeciesReference

036313
fast: false
reactant: 808265
reversible: false
product: 808301
reactant: 808253
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp
type: Reaction
is: ENSCAFG00000009534.2
product: 808289
is: http://identifiers.org/ec-code/2.4.1.102
name: Core 2 acetylglucosaminyltransferase, Golgi apparatus
product: 808277

835413
stoichiometry: 1.0
species: 740083
type: SpeciesReference

734525
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 2_C37H55NO38S2
type: Species

819088
stoichiometry: 1.0
species: 732392
type: SpeciesReference

743480
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 37_C62H104N4O46
type: Species

739123
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Galactose_C6H12O6
type: Species

753870
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Xanthine_C5H4N4O2
type: Species

772280
stoichiometry: 1.0
species: 744522
type: SpeciesReference

774145
stoichiometry: 1.0
species: 739987
type: SpeciesReference

754207
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Xyl-L-Ser (protein)_C5H9O4X
type: Species

785392
stoichiometry: 1.0
species: 745411
type: SpeciesReference

840099
stoichiometry: 1.0
species: 750902
type: SpeciesReference

758242
stoichiometry: 3.0
species: 734091
type: SpeciesReference

814432
stoichiometry: 1.0
species: 747099
type: SpeciesReference

776807
stoichiometry: 1.0
species: 734030
type: SpeciesReference

759196
stoichiometry: 1.0
species: 727612
type: SpeciesReference

852724
stoichiometry: 1.0
species: 735938
type: SpeciesReference

831450
stoichiometry: 1.0
species: 740518
type: SpeciesReference

805285
stoichiometry: 1.0
species: 748873
type: SpeciesReference

797325
stoichiometry: 1.0
species: 743709
type: SpeciesReference

808181
stoichiometry: 1.0
species: 727672
type: SpeciesReference

031367
is: ENSCAFG00000000752.2
name: Ceramide kinase
product: 763113
reactant: 763065
is: http://identifiers.org/ec-code/2.7.1.138
product: 763101
reversible: false
type: Reaction
reactant: 763077
notes: R_CERK subsystem: Sphingolipid Metabolism R_CERK equation: [c] : atp + crm_hs --> adp + crmp_hs + h
fast: false
product: 763089

782162
stoichiometry: 1.0
species: 754343
type: SpeciesReference

732140
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: arachidyl carnitine_C27H53NO4
type: Species

039803
type: Reaction
fast: false
is: ENSCAFG00000024323.1
is: ENSCAFG00000007081.2
is: ENSCAFG00000011634.1
is: ENSCAFG00000000734.2
is: ENSCAFG00000012453.2
is: ENSCAFG00000001401.2
is: ENSCAFG00000003395.2
is: ENSCAFG00000004552.2
is: ENSCAFG00000017823.2
is: ENSCAFG00000023339.1
is: ENSCAFG00000023331.1
is: ENSCAFG00000020173.2
name: glyceraldehyde-3-phosphate dehydrogenase
is: ENSCAFG00000012341.2
is: ENSCAFG00000015077.2
product: 841317
reactant: 841269
is: ENSCAFG00000023617.1
is: ENSCAFG00000008179.2
product: 841329
is: ENSCAFG00000000489.2
notes: R_GAPD subsystem: Glycolysis/Gluconeogenesis R_GAPD equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh
is: ENSCAFG00000006986.2
is: ENSCAFG00000001135.2
is: ENSCAFG00000013374.2
is: http://identifiers.org/ec-code/1.2.1.12
is: ENSCAFG00000007185.2
is: ENSCAFG00000007743.2
is: ENSCAFG00000010472.2
is: ENSCAFG00000007639.2
is: ENSCAFG00000002182.2
is: ENSCAFG00000010618.1
product: 841305
is: ENSCAFG00000014037.2
is: ENSCAFG00000020229.1
reactant: 841281
is: ENSCAFG00000017475.2
reactant: 841293
reversible: true
is: ENSCAFG00000020145.2
is: ENSCAFG00000002325.2
is: ENSCAFG00000010116.2

744844
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Leukotriene B4_C20H31O4
type: Species

791750
stoichiometry: 1.0
species: 737031
type: SpeciesReference

853650
stoichiometry: 1.0
species: 730391
type: SpeciesReference

846888
stoichiometry: 1.0
species: 743276
type: SpeciesReference

829133
stoichiometry: 1.0
species: 741151
type: SpeciesReference

837676
stoichiometry: 1.0
species: 741271
type: SpeciesReference

751977
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S
type: Species

775751
stoichiometry: 2.0
species: 746930
type: SpeciesReference

744012
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 3_C93H152N6O67X
type: Species

810447
stoichiometry: 1.0
species: 746918
type: SpeciesReference

768963
stoichiometry: 1.0
species: 739827
type: SpeciesReference

752605
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N6,N6,N6-Trimethyl-L-lysine_C9H20N2O2
type: Species

749683
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Pregnenolone_C21H32O2
type: Species

032402
reversible: true
name: calcium / sodium antiporter (1:3), reversible
is: ENSCAFG00000023592.1
reactant: 772847
is: ENSCAFG00000004140.2
notes: R_CAt7r subsystem: Transport, Extracellular R_CAt7r equation: ca2[c] + (3) na1[e] <==> ca2[e] + (3) na1[c]
product: 772859
product: 772871
fast: false
is: ENSCAFG00000008218.2
is: ENSCAFG00000016611.2
is: ENSCAFG00000006475.2
reactant: 772835
type: Reaction

737822
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: estrone glucuronide_C24H30O8
type: Species

817005
stoichiometry: 1.0
species: 730319
type: SpeciesReference

754428
stoichiometry: 1.0
species: 739003
type: SpeciesReference

730319
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)2 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1_C58H102N3O31FULLRCO
type: Species

813482
stoichiometry: 1.0
species: 747173
type: SpeciesReference

757832
stoichiometry: 1.0
species: 730862
type: SpeciesReference

754813
stoichiometry: 1.0
species: 742794
type: SpeciesReference

750745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62
type: Species

813772
stoichiometry: 1.0
species: 750056
type: SpeciesReference

757759
stoichiometry: 1.0
species: 749731
type: SpeciesReference

747662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Nervonyl carnitine_C31H59NO4
type: Species

838753
stoichiometry: 1.0
species: 750273
type: SpeciesReference

726404
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _12R-Hydroperoxyeicosatetraenoate_C20H31O4
type: Species

781096
stoichiometry: 1.0
species: 729416
type: SpeciesReference

837231
stoichiometry: 1.0
species: 752878
type: SpeciesReference

740120
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glutaryl-CoA_C26H37N7O19P3S
type: Species

731453
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _2-Oxoglutarate_C5H4O5
type: Species

038331
product: 828254
reactant: 828182
product: 828230
fast: false
product: 828242
reactant: 828206
product: 828218
reversible: true
type: Reaction
is: ENSCAFG00000006742.2
is: http://identifiers.org/ec-code/1.3.1.2
reactant: 828194
notes: R_DURAD2 subsystem: Pyrimidine Catabolism R_DURAD2 equation: [c] : 56dthm + nadp <==> h + nadph + thym R_DURAD subsystem: Pyrimidine Catabolism R_DURAD equation: [c] : 56dura + nadp <==> h + nadph + ura

849224
stoichiometry: 2.0
species: 734525
type: SpeciesReference

793980
stoichiometry: 1.0
species: 726596
type: SpeciesReference

778227
stoichiometry: 1.0
species: 747173
type: SpeciesReference

764504
stoichiometry: 1.0
species: 750818
type: SpeciesReference

828616
stoichiometry: 1.0
species: 750020
type: SpeciesReference

735047
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b_C45H64N2O51S5X
type: Species

817535
stoichiometry: 1.0
species: 734175
type: SpeciesReference

755707
stoichiometry: 1.0
species: 742843
type: SpeciesReference

742031
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 13_C55H83N3O61S5
type: Species

807615
stoichiometry: 1.0
species: 747173
type: SpeciesReference

816885
stoichiometry: 1.0
species: 731755
type: SpeciesReference

793258
stoichiometry: 2.0
species: 745675
type: SpeciesReference

826013
stoichiometry: 1.0
species: 735553
type: SpeciesReference

032859
product: 776831
type: Reaction
reactant: 776782
product: 776819
reactant: 776770
product: 776855
reactant: 776746
product: 776794
is: ENSCAFG00000013617.2
product: 776843
reversible: false
is: http://identifiers.org/ec-code/1.1.1.42
reactant: 776758
notes: R_ICDHy subsystem: Citric Acid Cycle R_ICDHy equation: [c] : icit + nadp --> akg + co2 + nadph R_ICDHyp subsystem: Citric Acid Cycle R_ICDHyp equation: [x] : icit + nadp --> akg + co2 + nadph
product: 776807
fast: false

842972
stoichiometry: 1.0
species: 736922
type: SpeciesReference

772725
stoichiometry: 1.0
species: 746750
type: SpeciesReference

825796
stoichiometry: 1.0
species: 739827
type: SpeciesReference

790438
stoichiometry: 1.0
species: 733189
type: SpeciesReference

765741
stoichiometry: 1.0
species: 751518
type: SpeciesReference

758895
stoichiometry: 6.0
species: 741428
type: SpeciesReference

038779
fast: false
product: 831594
is: ENSCAFG00000008737.2
is: ENSCAFG00000015041.2
product: 831582
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.119
is: ENSCAFG00000011134.2
notes: R_DOLASNT_Ler subsystem: N-Glycan Biosynthesis R_DOLASNT_Ler equation: [r] : Asn-X-Ser/Thr + (0.1) g3m8mpdol_L --> (0.1) doldp_L + g3m8masn + h R_DOLASNT_Uer subsystem: N-Glycan Biosynthesis R_DOLASNT_Uer equation: [r] : Asn-X-Ser/Thr + (0.1) g3m8mpdol_U --> (0.1) doldp_U + g3m8masn + h
reactant: 831546
product: 831606
reversible: false
product: 831618
reactant: 831570
reactant: 831558
is: ENSCAFG00000004148.2

742284
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 9_C61H87N3O76S8
type: Species

727648
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methoxy-4-hydroxymandelate_C9H9O5
type: Species

788553
stoichiometry: 1.0
species: 750056
type: SpeciesReference

730196
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetol_C3H6O2
type: Species

779904
stoichiometry: 1.0
species: 731297
type: SpeciesReference

747516
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nitric oxide_NO
type: Species

806653
stoichiometry: 1.0
species: 732465
type: SpeciesReference

751542
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: starch, structure 2 (1,6-{2[1,4-Glc], [1,4-Glc]})_C18H32O16
type: Species

818107
stoichiometry: 1.0
species: 727576
type: SpeciesReference

840761
stoichiometry: 3.0
species: 747722
type: SpeciesReference

851249
stoichiometry: 1.0
species: 747148
type: SpeciesReference

830397
stoichiometry: 1.0
species: 733654
type: SpeciesReference

035588
is: http://identifiers.org/ec-code/2.4.1.142
product: 801573
notes: R_BDMT_U subsystem: N-Glycan Biosynthesis R_BDMT_U equation: [c] : (0.1) chito2pdol_U + gdpmann --> gdp + h + (0.1) mpdol_U R_BDMT_L subsystem: N-Glycan Biosynthesis R_BDMT_L equation: [c] : (0.1) chito2pdol_L + gdpmann --> gdp + h + (0.1) mpdol_L
reactant: 801548
fast: false
product: 801612
is: ENSCAFG00000019111.2
type: Reaction
reactant: 801560
product: 801586
reversible: false
reactant: 801536
product: 801599

776927
stoichiometry: 1.0
species: 744796
type: SpeciesReference

797662
stoichiometry: 1.0
species: 730922
type: SpeciesReference

812650
stoichiometry: 3.0
species: 741259
type: SpeciesReference

040477
notes: R_SPMS subsystem: Urea cycle/amino group metabolism R_SPMS equation: [c] : ametam + ptrc --> 5mta + h + spmd
fast: false
is: ENSCAFG00000016733.2
product: 847378
reactant: 847353
product: 847390
name: spermidine synthase
reversible: false
is: http://identifiers.org/ec-code/2.5.1.16
type: Reaction
reactant: 847365
product: 847402

770901
stoichiometry: 1.0
species: 727991
type: SpeciesReference

727384
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
type: Species

845992
stoichiometry: 18.0
species: 730922
type: SpeciesReference

730088
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Acetaldehyde_C2H4O
type: Species

739268
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Type IB glycolipid_C56H99N2O31FULLRCO
type: Species

742394
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 2_C37H56NO31X
type: Species

807207
stoichiometry: 1.0
species: 733981
type: SpeciesReference

757188
stoichiometry: 1.0
species: 752109
type: SpeciesReference

833398
stoichiometry: 2.0
species: 732477
type: SpeciesReference

036724
type: Reaction
product: 811240
reactant: 811204
notes: R_GLCNACPT_U subsystem: N-Glycan Biosynthesis R_GLCNACPT_U equation: [c] : (0.1) dolp_U + uacgam --> (0.1) naglc2p_U + ump R_GLCNACPT_L subsystem: N-Glycan Biosynthesis R_GLCNACPT_L equation: [c] : (0.1) dolp_L + uacgam --> (0.1) naglc2p_L + ump
product: 811216
fast: false
reversible: false
is: http://identifiers.org/ec-code/2.7.8.15
product: 811228
reactant: 811180
is: ENSCAFG00000012302.2
reactant: 811192

792462
stoichiometry: 1.0
species: 739027
type: SpeciesReference

852845
stoichiometry: 1.0
species: 746437
type: SpeciesReference

777421
stoichiometry: 1.0
species: 744650
type: SpeciesReference

035973
product: 805020
reactant: 804587
reactant: 804743
reactant: 804731
product: 804984
product: 804875
product: 805153
product: 805165
reactant: 804767
product: 804887
reactant: 804623
product: 804911
type: Reaction
product: 804839
is: ENSCAFG00000012076.1
product: 804899
reactant: 804539
reversible: false
reactant: 804454
product: 804923
product: 804851
reactant: 804659
reactant: 804647
reactant: 804382
product: 804791
product: 804863
product: 804935
reactant: 804478
reactant: 804707
product: 805032
product: 804947
product: 804959
reactant: 804406
reactant: 804575
reactant: 804695
reactant: 804683
product: 805081
fast: false
product: 805093
reactant: 804599
reactant: 804755
product: 805045
product: 805057
reactant: 804442
product: 805069
reactant: 804611
product: 804971
reactant: 804466
product: 805117
reactant: 804527
reactant: 804430
reactant: 804515
reactant: 804394
product: 805129
reactant: 804635
product: 804803
reactant: 804719
notes: R_RTOTALCRNt subsystem: Carnitine shuttle R_RTOTALCRNt equation: Rtotalcrn[c] --> Rtotalcrn[m] R_LNLNCGCRNt subsystem: Carnitine shuttle R_LNLNCGCRNt equation: lnlncgcrn[c] --> lnlncgcrn[m] R_ACRNtm subsystem: Transport, Mitochondrial R_ACRNtm equation: acrn[c] --> acrn[m] R_LNLNCACRNt subsystem: Carnitine shuttle R_LNLNCACRNt equation: lnlncacrn[c] --> lnlncacrn[m] R_DLNLCGCRNt subsystem: Carnitine shuttle R_DLNLCGCRNt equation: dlnlcgcrn[c] --> dlnlcgcrn[m] R_STRDNCCRNt subsystem: Carnitine shuttle R_STRDNCCRNt equation: strdnccrn[c] --> strdnccrn[m] R_CRNtim subsystem: Transport, Mitochondrial R_CRNtim equation: crn[m] --> crn[c] R_TETTET6CRNt subsystem: Carnitine shuttle R_TETTET6CRNt equation: tettet6crn[c] --> tettet6crn[m] R_RTOTAL2CRNt subsystem: Carnitine shuttle R_RTOTAL2CRNt equation: Rtotal2crn[c] --> Rtotal2crn[m] R_DCSPTN1CRNt subsystem: Carnitine shuttle R_DCSPTN1CRNt equation: dcsptn1crn[c] --> dcsptn1crn[m] R_C161CRN2t subsystem: Carnitine shuttle R_C161CRN2t equation: hdd2crn[c] --> hdd2crn[m] R_C181CRNt subsystem: Carnitine shuttle R_C181CRNt equation: odecrn[c] --> odecrn[m] R_EICOSTETCRNt subsystem: Carnitine shuttle R_EICOSTETCRNt equation: eicostetcrn[c] --> eicostetcrn[m] R_TTDCRNt subsystem: Carnitine shuttle R_TTDCRNt equation: ttdcrn[c] --> ttdcrn[m] R_TMNDNCCRNt subsystem: Carnitine shuttle R_TMNDNCCRNt equation: tmndnccrn[c] --> tmndnccrn[m] R_CLPNDCRNt subsystem: Carnitine shuttle R_CLPNDCRNt equation: clpndcrn[c] --> clpndcrn[m] R_LGNCCRNt subsystem: Carnitine shuttle R_LGNCCRNt equation: lgnccrn[c] --> lgnccrn[m] R_VACCCRNt subsystem: Carnitine shuttle R_VACCCRNt equation: vacccrn[c] --> vacccrn[m] R_ADRNCRNt subsystem: Carnitine shuttle R_ADRNCRNt equation: adrncrn[c] --> adrncrn[m] R_NRVNCCRNt subsystem: Carnitine shuttle R_NRVNCCRNt equation: nrvnccrn[c] --> nrvnccrn[m] R_TETPENT6CRNt subsystem: Carnitine shuttle R_TETPENT6CRNt equation: tetpent6crn[c] --> tetpent6crn[m] R_LNELDCCRNt subsystem: Carnitine shuttle R_LNELDCCRNt equati…
product: 804779
product: 805141
product: 804815
product: 804996
product: 804827
reactant: 804502
product: 805105
reactant: 804563
reactant: 804551
reactant: 804490
product: 805008
reactant: 804671
reactant: 804418

854328
stoichiometry: 9.0
species: 747294
type: SpeciesReference

789531
stoichiometry: 1.0
species: 735276
type: SpeciesReference

849791
stoichiometry: 1.0
species: 739414
type: SpeciesReference

811276
stoichiometry: 5.0
species: 735216
type: SpeciesReference

781957
stoichiometry: 1.0
species: 729979
type: SpeciesReference

796296
stoichiometry: 1.0
species: 754355
type: SpeciesReference

836134
stoichiometry: 1.0
species: 753314
type: SpeciesReference

762458
stoichiometry: 1.0
species: 749671
type: SpeciesReference

844495
stoichiometry: 3.0
species: 741283
type: SpeciesReference

821727
stoichiometry: 2.0
species: 746930
type: SpeciesReference

851032
stoichiometry: 1.0
species: 747002
type: SpeciesReference

034854
product: 793762
name: acetyl-CoA hydrolase
type: Reaction
product: 793750
is: ENSCAFG00000008698.2
reversible: false
is: http://identifiers.org/ec-code/3.1.2.1
reactant: 793726
product: 793738
fast: false
reactant: 793714
notes: R_ACOAHi subsystem: Pyruvate Metabolism R_ACOAHi equation: [c] : accoa + h2o --> ac + coa + h

736413
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-Dihydroorotate_C5H5N2O4
type: Species

778952
stoichiometry: 1.0
species: 738207
type: SpeciesReference

823190
stoichiometry: 1.0
species: 747062
type: SpeciesReference

808926
stoichiometry: 1.0
species: 741283
type: SpeciesReference

740886
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Oxidized glutathione_C20H30N6O12S2
type: Species

827028
stoichiometry: 1.0
species: 730922
type: SpeciesReference

761090
stoichiometry: 2.0
species: 740762
type: SpeciesReference

757601
stoichiometry: 4.0
species: 734018
type: SpeciesReference

839847
stoichiometry: 1.0
species: 751202
type: SpeciesReference

784839
stoichiometry: 4.0
species: 741283
type: SpeciesReference

746049
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Mannose 6-phosphate_C6H11O9P
type: Species

038160
is: http://identifiers.org/ec-code/3.1.1.23
reactant: 826844
reversible: false
product: 826882
notes: R_LPSe subsystem: Triacylglycerol Synthesis R_LPSe equation: [e] : h2o + tag_hs --> Rtotal3 + dag_hs + h R_LPS2e subsystem: Fatty Acid Metabolism R_LPS2e equation: [e] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS3e subsystem: Fatty Acid Metabolism R_LPS3e equation: [e] : h2o + mag_hs --> Rtotal2 + glyc + h
is: http://identifiers.org/ec-code/3.1.1.3
type: Reaction
product: 826894
product: 826906
reactant: 826808
reactant: 826820
product: 826930
fast: false
is: ENSCAFG00000016560.2
product: 826918
product: 826869
reactant: 826832
product: 826856

764613
stoichiometry: 1.0
species: 733981
type: SpeciesReference

778336
stoichiometry: 2.0
species: 749466
type: SpeciesReference

742188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 25_C23H37O21
type: Species

757540
stoichiometry: 2.0
species: 728257
type: SpeciesReference

830777
stoichiometry: 1.0
species: 748314
type: SpeciesReference

762944
stoichiometry: 1.0
species: 744784
type: SpeciesReference

738015
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose 6-phosphate_C6H11O9P
type: Species

740011
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: L-Glutamate_C5H8NO4
type: Species

835966
stoichiometry: 1.0
species: 741151
type: SpeciesReference

853386
stoichiometry: 1.0
species: 731972
type: SpeciesReference

750854
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Saccharopine_C11H19N2O6
type: Species

813881
stoichiometry: 1.0
species: 737618
type: SpeciesReference

810507
stoichiometry: 1.0
species: 751820
type: SpeciesReference

841497
stoichiometry: 1.0
species: 738039
type: SpeciesReference

816993
stoichiometry: 1.0
species: 738702
type: SpeciesReference

777579
stoichiometry: 1.0
species: 752617
type: SpeciesReference

814299
stoichiometry: 1.0
species: 732441
type: SpeciesReference

822803
stoichiometry: 1.0
species: 740265
type: SpeciesReference

842864
stoichiometry: 1.0
species: 729714
type: SpeciesReference

797433
stoichiometry: 1.0
species: 743987
type: SpeciesReference

751651
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Succinate_C4H4O4
type: Species

772436
stoichiometry: 1.0
species: 744024
type: SpeciesReference

839991
stoichiometry: 1.0
species: 741259
type: SpeciesReference

828724
stoichiometry: 1.0
species: 751844
type: SpeciesReference

795418
stoichiometry: 1.0
species: 741259
type: SpeciesReference

817427
stoichiometry: 1.0
species: 747185
type: SpeciesReference

849332
stoichiometry: 24.0
species: 741296
type: SpeciesReference

808061
stoichiometry: 1.0
species: 733738
type: SpeciesReference

846064
stoichiometry: 1.0
species: 728583
type: SpeciesReference

854037
stoichiometry: 1.0
species: 746978
type: SpeciesReference

804899
stoichiometry: 1.0
species: 741729
type: SpeciesReference

823550
stoichiometry: 3.0
species: 735373
type: SpeciesReference

802579
stoichiometry: 1.0
species: 745025
type: SpeciesReference

820908
stoichiometry: 1.0
species: 736535
type: SpeciesReference

731561
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Alanine_C3H7NO2
type: Species

775995
stoichiometry: 3.0
species: 746930
type: SpeciesReference

802277
stoichiometry: 1.0
species: 747123
type: SpeciesReference

813060
stoichiometry: 1.0
species: 749200
type: SpeciesReference

831703
stoichiometry: 1.0
species: 738039
type: SpeciesReference

834469
stoichiometry: 2.0
species: 741259
type: SpeciesReference

763536
stoichiometry: 1.0
species: 734091
type: SpeciesReference

790654
stoichiometry: 1.0
species: 735709
type: SpeciesReference

834991
stoichiometry: 1.0
species: 753399
type: SpeciesReference

792571
stoichiometry: 1.0
species: 729919
type: SpeciesReference

811818
stoichiometry: 1.0
species: 745399
type: SpeciesReference

806761
stoichiometry: 1.0
species: 727323
type: SpeciesReference

736303
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Dehydroepiandrosterone sulfate_C19H27O5S
type: Species

777144
stoichiometry: 1.0
species: 737846
type: SpeciesReference

800087
stoichiometry: 1.0
species: 740229
type: SpeciesReference

762301
stoichiometry: 1.0
species: 749719
type: SpeciesReference

760175
stoichiometry: 1.0
species: 747050
type: SpeciesReference

727275
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _3'-AMP_C10H12N5O7P
type: Species

843371
stoichiometry: 1.0
species: 740651
type: SpeciesReference

796140
stoichiometry: 1.0
species: 743697
type: SpeciesReference

811168
stoichiometry: 1.0
species: 753423
type: SpeciesReference

788445
stoichiometry: 1.0
species: 741296
type: SpeciesReference

033925
reactant: 785079
reactant: 785067
product: 785103
product: 785091
reactant: 785031
type: Reaction
is: ENSCAFG00000005370.2
reversible: false
product: 785115
product: 785127
reactant: 785043
reactant: 785055
notes: R_P4508B13r subsystem: Bile Acid Biosynthesis R_P4508B13r equation: [r] : h + nadh + o2 + xol7aone --> h2o + nad + xoldiolone R_P4508B11r subsystem: Bile Acid Biosynthesis R_P4508B11r equation: [r] : h + nadph + o2 + xol7aone --> h2o + nadp + xoldiolone
fast: false

854761
stoichiometry: 1.0
species: 741296
type: SpeciesReference

758787
stoichiometry: 1.0
species: 752593
type: SpeciesReference

812541
stoichiometry: 1.0
species: 732417
type: SpeciesReference

852280
stoichiometry: 1.0
species: 732152
type: SpeciesReference

772835
stoichiometry: 1.0
species: 732997
type: SpeciesReference

847558
stoichiometry: 1.0
species: 733859
type: SpeciesReference

846040
stoichiometry: 1.0
species: 726235
type: SpeciesReference

035433
fast: false
notes: R_AKGMALtm subsystem: Transport, Mitochondrial R_AKGMALtm equation: akg[m] + mal-L[c] <==> akg[c] + mal-L[m]
product: 800544
product: 800532
name: alpha-ketoglutarate/malate transporter
type: Reaction
reactant: 800508
reactant: 800520
reversible: true
is: ENSCAFG00000015836.2

827137
stoichiometry: 1.0
species: 747698
type: SpeciesReference

737374
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dUTP_C9H11N2O14P3
type: Species

034745
fast: false
type: Reaction
product: 792811
reactant: 792727
reactant: 792715
product: 792799
reactant: 792739
product: 792835
product: 792823
is: ENSCAFG00000000083.2
notes: R_H6_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ETer equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H3ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3ETer equation: [r] : m2gacpail_hs + pe_hs --> dag_hs + memgacpail_hs R_H4ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ETer equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + m2emgacpail_hs R_H7_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_ETer equation: [r] : emem2gacpail_hs + pe_hs --> dag_hs + gpi_hs R_H2ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H2ETer equation: [r] : mgacpail_hs + pe_hs --> dag_hs + emgacpail_hs
reactant: 792763
reactant: 792751
product: 792787
reversible: false
product: 792847
reactant: 792775

816452
stoichiometry: 1.0
species: 735469
type: SpeciesReference

777204
stoichiometry: 1.0
species: 752816
type: SpeciesReference

757296
stoichiometry: 1.0
species: 732116
type: SpeciesReference

038016
fast: false
is: ENSCAFG00000025299.1
is: ENSCAFG00000005609.2
reactant: 825664
product: 825736
reactant: 825676
reversible: false
product: 825748
reactant: 825700
product: 825712
product: 825760
reactant: 825688
is: ENSCAFG00000011544.2
is: http://identifiers.org/ec-code/1.1.1.204
notes: R_XAO2x subsystem: Purine Catabolism R_XAO2x equation: [x] : h2o + hxan + o2 --> h2o2 + xan R_XAOx subsystem: Purine Catabolism R_XAOx equation: [x] : h2o + o2 + xan --> h2o2 + urate R_XANDp subsystem: Purine Catabolism R_XANDp equation: [x] : h2o + nad + xan --> h + nadh + urate
product: 825724
is: ENSCAFG00000023664.1
type: Reaction
reactant: 825652

768549
stoichiometry: 1.0
species: 732044
type: SpeciesReference

799461
stoichiometry: 1.0
species: 751094
type: SpeciesReference

038221
product: 827221
reactant: 827185
type: Reaction
product: 827209
notes: R_CSm subsystem: Citric Acid Cycle R_CSm equation: [m] : accoa + h2o + oaa --> cit + coa + h
is: ENSCAFG00000000115.2
reactant: 827197
fast: false
name: citrate synthase
product: 827233
reversible: false
reactant: 827173

803086
stoichiometry: 2.0
species: 746930
type: SpeciesReference

823998
stoichiometry: 6.0
species: 733884
type: SpeciesReference

853230
stoichiometry: 1.0
species: 731984
type: SpeciesReference

728003
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _4-Aminobutanoate_C4H9NO2
type: Species

830669
stoichiometry: 1.0
species: 728607
type: SpeciesReference

803206
stoichiometry: 1.0
species: 731755
type: SpeciesReference

746569
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 4-phosphate_C6H11O9P
type: Species

771469
stoichiometry: 1.0
species: 735155
type: SpeciesReference

830071
stoichiometry: 1.0
species: 733933
type: SpeciesReference

832016
stoichiometry: 1.0
species: 739939
type: SpeciesReference

779579
stoichiometry: 1.0
species: 740862
type: SpeciesReference

797958
stoichiometry: 1.0
species: 732092
type: SpeciesReference

809651
stoichiometry: 1.0
species: 736583
type: SpeciesReference

797734
stoichiometry: 1.0
species: 752013
type: SpeciesReference

849454
stoichiometry: 2.0
species: 743336
type: SpeciesReference

730488
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GlcNAc-Gal globoside (homo sapiens)_C58H102N3O32FULLRCO
type: Species

823442
stoichiometry: 7.0
species: 753459
type: SpeciesReference

737508
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ecgonine methyl ester_C10H17NO3
type: Species

788782
stoichiometry: 1.0
species: 739499
type: SpeciesReference

851140
stoichiometry: 2.0
species: 741308
type: SpeciesReference

746134
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Melatonin_C13H16N2O2
type: Species

768855
stoichiometry: 1.0
species: 727154
type: SpeciesReference

764226
stoichiometry: 1.0
species: 740922
type: SpeciesReference

825604
stoichiometry: 1.0
species: 749297
type: SpeciesReference

804731
stoichiometry: 1.0
species: 741717
type: SpeciesReference

030909
reactant: 758666
product: 758678
notes: R_RBFK subsystem: Riboflavin Metabolism R_RBFK equation: [c] : atp + ribflv --> adp + fmn + h
name: riboflavin kinase
product: 758702
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.26
reversible: false
fast: false
reactant: 758654
is: ENSCAFG00000001650.2
product: 758690

798812
stoichiometry: 9.0
species: 737253
type: SpeciesReference

827546
stoichiometry: 1.0
species: 751190
type: SpeciesReference

738305
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Folate_C19H18N7O6
type: Species

781228
stoichiometry: 1.0
species: 748146
type: SpeciesReference

807555
stoichiometry: 1.0
species: 748959
type: SpeciesReference

769372
stoichiometry: 1.0
species: 743384
type: SpeciesReference

778530
stoichiometry: 1.0
species: 741163
type: SpeciesReference

740313
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glycerol_C3H8O3
type: Species

787723
stoichiometry: 1.0
species: 752593
type: SpeciesReference

756116
stoichiometry: 1.0
species: 739668
type: SpeciesReference

799677
stoichiometry: 3.0
species: 741259
type: SpeciesReference

848197
stoichiometry: 1.0
species: 741332
type: SpeciesReference

746906
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: ((N-acetyl-D-glucosaminyl)4-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C66H109N6O45X
type: Species

838601
stoichiometry: 1.0
species: 741983
type: SpeciesReference

040753
modifier: 851846
modifier: 851833
product: 851701
product: 851761
product: 851725
reactant: 851617
product: 851749
reactant: 851629
modifier: 851809
reactant: 851641
modifier: 851894
modifier: 851870
product: 851713
product: 851773
modifier: 851797
notes: R_AHANDROSTANGLCte subsystem: Transport, Extracellular R_AHANDROSTANGLCte equation: ahandrostanglc[c] + atp[c] + h2o[c] --> adp[c] + ahandrostanglc[e] + h[c] + pi[c] R_5ADTSTSTERONEGLCte subsystem: Transport, Extracellular R_5ADTSTSTERONEGLCte equation: _5adtststeroneglc[c] + atp[c] + h2o[c] --> 5adtststeroneglc[e] + adp[c] + h[c] + pi[c] R_BILDGLCURte subsystem: Transport, Extracellular R_BILDGLCURte equation: atp[c] + bildglcur[c] + h2o[c] <==> adp[c] + bildglcur[e] + h[c] + pi[c] R_BILGLCURte subsystem: Transport, Extracellular R_BILGLCURte equation: atp[c] + bilglcur[c] + h2o[c] <==> adp[c] + bilglcur[e] + h[c] + pi[c] R_TSTSTERONEGLCte subsystem: Transport, Extracellular R_TSTSTERONEGLCte equation: atp[c] + h2o[c] + tststeroneglc[c] --> adp[c] + h[c] + pi[c] + tststeroneglc[e] R_ANDRSTRNGLCte subsystem: Transport, Extracellular R_ANDRSTRNGLCte equation: andrstrnglc[c] + atp[c] + h2o[c] --> adp[c] + andrstrnglc[e] + h[c] + pi[c] R_ESTRIOLGLCte subsystem: Transport, Extracellular R_ESTRIOLGLCte equation: atp[c] + estriolglc[c] + h2o[c] --> adp[c] + estriolglc[e] + h[c] + pi[c]
product: 851785
modifier: 851858
product: 851737
reactant: 851677
modifier: 851821
reversible: false
fast: false
reactant: 851689
reactant: 851653
is: ENSCAFG00000018208.2
modifier: 851882
reactant: 851665
type: Reaction

783740
stoichiometry: 1.0
species: 740922
type: SpeciesReference

767594
stoichiometry: 1.0
species: 729919
type: SpeciesReference

771046
stoichiometry: 1.0
species: 730729
type: SpeciesReference

805393
stoichiometry: 1.0
species: 751627
type: SpeciesReference

753387
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: UDP-D-xylose_C14H20N2O16P2
type: Species

730209
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetone_C3H6O
type: Species

783535
stoichiometry: 1.0
species: 749466
type: SpeciesReference

039286
reversible: false
fast: false
reactant: 836701
is: http://identifiers.org/ec-code/4.1.1.32
product: 836726
product: 836714
reactant: 836689
is: ENSCAFG00000012065.2
name: Phosphoenolpyruvate carboxykinase (GTP)
notes: R_PEPCK subsystem: Glycolysis/Gluconeogenesis R_PEPCK equation: [c] : gtp + oaa --> co2 + gdp + pep
product: 836738
type: Reaction

814589
stoichiometry: 1.0
species: 744676
type: SpeciesReference

754536
stoichiometry: 1.0
species: 742139
type: SpeciesReference

756044
stoichiometry: 1.0
species: 751385
type: SpeciesReference

031885
product: 767558
type: Reaction
product: 767546
reactant: 767510
reactant: 767522
fast: false
product: 767582
product: 767570
is: http://identifiers.org/ec-code/2.7.1.59
is: http://identifiers.org/ec-code/2.7.1.60
notes: R_ACGAMK subsystem: Aminosugar Metabolism R_ACGAMK equation: [c] : acgam + atp --> acgam6p + adp + h R_AMANK subsystem: Aminosugar Metabolism R_AMANK equation: [c] : acmana + atp --> acmanap + adp + h
reversible: false
is: ENSCAFG00000009100.2
reactant: 767534

847414
stoichiometry: 1.0
species: 753302
type: SpeciesReference

770582
stoichiometry: 1.0
species: 749454
type: SpeciesReference

747307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Ammonium_H4N
type: Species

848089
stoichiometry: 35.0
species: 747038
type: SpeciesReference

786208
stoichiometry: 1.0
species: 741235
type: SpeciesReference

758678
stoichiometry: 1.0
species: 730922
type: SpeciesReference

829289
stoichiometry: 1.0
species: 746557
type: SpeciesReference

031041
name: choline phosphotransferase
fast: false
product: 760006
reactant: 759970
reversible: false
reactant: 759958
product: 759982
type: Reaction
is: ENSCAFG00000007213.2
product: 759994
notes: R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs

786352
stoichiometry: 1.0
species: 728257
type: SpeciesReference

745315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: gamma-linolenyl carnitine_C25H43NO4
type: Species

726125
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

774484
stoichiometry: 1.0
species: 741259
type: SpeciesReference

812373
stoichiometry: 1.0
species: 744676
type: SpeciesReference

767690
stoichiometry: 1.0
species: 741308
type: SpeciesReference

839570
stoichiometry: 1.0
species: 737907
type: SpeciesReference

842326
stoichiometry: 1.0
species: 747430
type: SpeciesReference

732296
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N(omega)-(L-Arginino)succinate_C10H17N4O6
type: Species

744952
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

835304
stoichiometry: 1.0
species: 744084
type: SpeciesReference

796794
stoichiometry: 2.0
species: 752655
type: SpeciesReference

761331
stoichiometry: 1.0
species: 753157
type: SpeciesReference

801891
stoichiometry: 4.0
species: 753206
type: SpeciesReference

817114
stoichiometry: 1.0
species: 730343
type: SpeciesReference

778746
stoichiometry: 1.0
species: 751542
type: SpeciesReference

031475
is: http://identifiers.org/ec-code/6.3.4.2
product: 763804
reactant: 763779
product: 763791
fast: false
reactant: 763767
reversible: false
type: Reaction
reactant: 763755
notes: R_CTPS1 subsystem: Nucleotides R_CTPS1 equation: [c] : atp + nh4 + utp --> adp + ctp + (2) h + pi
product: 763816
is: ENSCAFG00000003623.2
name: CTP synthase (NH3)
product: 763828

757989
stoichiometry: 2.0
species: 746267
type: SpeciesReference

852616
stoichiometry: 1.0
species: 751687
type: SpeciesReference

832665
stoichiometry: 2.0
species: 732441
type: SpeciesReference

758134
stoichiometry: 1.0
species: 744435
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Protoporphyrin_C34H32N4O4
type: Species

039116
notes: R_ACS2 subsystem: Propanoate Metabolism R_ACS2 equation: [c] : atp + coa + ppa --> amp + ppcoa + ppi R_ACCOAL subsystem: Propanoate Metabolism R_ACCOAL equation: [c] : atp + coa + ppa --> adp + pi + ppcoa R_ACS subsystem: Glycolysis/Gluconeogenesis R_ACS equation: [c] : ac + atp + coa --> accoa + amp + ppi
reactant: 834566
product: 834665
reversible: false
fast: false
product: 834639
is: http://identifiers.org/ec-code/6.2.1.1
product: 834626
reactant: 834590
product: 834652
product: 834602
reactant: 834578
type: Reaction
product: 834614
reactant: 834554
is: http://identifiers.org/ec-code/6.2.1.13
is: ENSCAFG00000007637.2

831342
stoichiometry: 1.0
species: 744585
type: SpeciesReference

800943
stoichiometry: 1.0
species: 739926
type: SpeciesReference

775860
stoichiometry: 1.0
species: 749466
type: SpeciesReference

847293
stoichiometry: 1.0
species: 742892
type: SpeciesReference

750598
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-13-retinol_C20H30O
type: Species

739534
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: glycocholate_C26H43NO6
type: Species

846779
stoichiometry: 1.0
species: 743144
type: SpeciesReference

764336
stoichiometry: 1.0
species: 741259
type: SpeciesReference

780578
stoichiometry: 1.0
species: 744976
type: SpeciesReference

789603
stoichiometry: 1.0
species: 735192
type: SpeciesReference

791233
stoichiometry: 1.0
species: 727747
type: SpeciesReference

844059
stoichiometry: 23.0
species: 741283
type: SpeciesReference

795862
stoichiometry: 1.0
species: 744253
type: SpeciesReference

850707
stoichiometry: 2.0
species: 744676
type: SpeciesReference

038888
reactant: 832280
reversible: false
is: ENSCAFG00000010466.2
reactant: 832268
reactant: 832304
product: 832352
type: Reaction
product: 832328
product: 832340
reactant: 832292
notes: R_DOLPGT3_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT3_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g2m8mpdol_L --> (0.1) dolp_L + (0.1) g3m8mpdol_L + h R_DOLPGT3_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT3_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g2m8mpdol_U --> (0.1) dolp_U + (0.1) g3m8mpdol_U + h
fast: false
product: 832364
product: 832316

735781
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: trans-Dodec-2-enoyl-CoA_C33H52N7O17P3S
type: Species

832941
stoichiometry: 1.0
species: 745711
type: SpeciesReference

735155
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CTP_C9H12N3O14P3
type: Species

037050
is: ENSCAFG00000007660.1
reactant: 813929
is: ENSCAFG00000006578.2
product: 813965
is: ENSCAFG00000001233.2
is: ENSCAFG00000006734.2
is: ENSCAFG00000016887.2
is: ENSCAFG00000019921.2
product: 813977
is: ENSCAFG00000006913.2
is: ENSCAFG00000011223.2
name: cytochrome c oxidase, mitochondrial Complex IV
is: ENSCAFG00000002387.2
is: ENSCAFG00000013550.2
is: ENSCAFG00000016664.1
product: 813953
is: ENSCAFG00000008403.2
fast: false
type: Reaction
reversible: false
product: 813989
is: ENSCAFG00000022726.1
notes: R_CYOOm3 subsystem: Oxidative Phosphorylation R_CYOOm3 equation: (4) focytC[m] + (7.92) h[m] + o2[m] --> (4) ficytC[m] + (4) h[c] + (1.96) h2o[m] + (0.02) o2s[m]
is: ENSCAFG00000001887.2
is: ENSCAFG00000007049.2
is: ENSCAFG00000017977.2
is: ENSCAFG00000005757.2
is: ENSCAFG00000006519.2
is: http://identifiers.org/ec-code/1.9.3.1
reactant: 813917
reactant: 813941

818810
stoichiometry: 1.0
species: 742807
type: SpeciesReference

793510
stoichiometry: 1.0
species: 742067
type: SpeciesReference

812227
stoichiometry: 1.0
species: 730982
type: SpeciesReference

753579
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Uridine_C9H12N2O6
type: Species

034408
is: ENSCAFG00000001514.2
notes: R_MCPST subsystem: Cysteine Metabolism R_MCPST equation: [c] : cyan + mercppyr --> h + pyr + tcynt
reactant: 789615
is: http://identifiers.org/ec-code/2.8.1.2
product: 789639
product: 789627
product: 789651
reversible: false
fast: false
name: _3-mercaptopyruvate sulfurtransferase
reactant: 789603
type: Reaction

738171
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose 1,6-bisphosphate_C6H10O12P2
type: Species

750020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Prostaglandin E2_C20H31O5
type: Species

038441
notes: R_P45039A1r subsystem: Bile Acid Biosynthesis R_P45039A1r equation: [r] : h + nadph + o2 + xol24oh --> h2o + nadp + xoltri24
product: 829265
product: 829253
reactant: 829229
reactant: 829217
reversible: false
product: 829241
reactant: 829205
fast: false
is: ENSCAFG00000002026.2
type: Reaction
reactant: 829193
name: oxysterol 7-alpha-hydroxylase

803508
stoichiometry: 6.0
species: 747050
type: SpeciesReference

779194
stoichiometry: 1.0
species: 747758
type: SpeciesReference

815678
stoichiometry: 1.0
species: 742479
type: SpeciesReference

805406
stoichiometry: 1.0
species: 733981
type: SpeciesReference

783463
stoichiometry: 1.0
species: 752217
type: SpeciesReference

039923
product: 841941
reactant: 841929
notes: R_ALAR subsystem: Alanine and Aspartate Metabolism R_ALAR equation: [c] : ala-L <==> ala-D
is: ENSCAFG00000006193.2
is: http://identifiers.org/ec-code/5.1.1.1
fast: false
reversible: true
name: alanine racemase
type: Reaction

802796
stoichiometry: 1.0
species: 740241
type: SpeciesReference

728872
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

796574
stoichiometry: 1.0
species: 749442
type: SpeciesReference

810892
stoichiometry: 1.0
species: 741283
type: SpeciesReference

837508
stoichiometry: 1.0
species: 732805
type: SpeciesReference

790871
stoichiometry: 1.0
species: 731042
type: SpeciesReference

791979
stoichiometry: 3.0
species: 731731
type: SpeciesReference

752061
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: tetracosapentaenoyl carnitine_C31H51NO4
type: Species

745531
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)_C49H88NO29PFULLRCO2FULLR2CO2
type: Species

734951
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 5_C31H47NO35S3
type: Species

801197
stoichiometry: 1.0
species: 751202
type: SpeciesReference

786076
stoichiometry: 1.0
species: 739926
type: SpeciesReference

777360
stoichiometry: 1.0
species: 729006
type: SpeciesReference

762034
stoichiometry: 1.0
species: 741259
type: SpeciesReference

835749
stoichiometry: 1.0
species: 743914
type: SpeciesReference

794489
stoichiometry: 1.0
species: 740433
type: SpeciesReference

834775
stoichiometry: 1.0
species: 730196
type: SpeciesReference

849115
stoichiometry: 1.0
species: 743324
type: SpeciesReference

735481
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dATP_C10H12N5O12P3
type: Species

843926
stoichiometry: 1.0
species: 744497
type: SpeciesReference

848655
stoichiometry: 1.0
species: 734939
type: SpeciesReference

736523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Deoxyinosine_C10H12N4O4
type: Species

779000
stoichiometry: 1.0
species: 753943
type: SpeciesReference

753423
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UMP_C9H11N2O9P
type: Species

803363
stoichiometry: 3.0
species: 747698
type: SpeciesReference

729991
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Acetate_C2H3O2
type: Species

728221
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Methylpentanal_C6H12O
type: Species

815184
stoichiometry: 1.0
species: 752533
type: SpeciesReference

728764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxykynurenamine_C9H13N2O2
type: Species

788228
stoichiometry: 1.0
species: 739827
type: SpeciesReference

836556
stoichiometry: 1.0
species: 727600
type: SpeciesReference

752496
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Threonine_C4H9NO3
type: Species

781808
stoichiometry: 1.0
species: 747050
type: SpeciesReference

799317
stoichiometry: 1.0
species: 751082
type: SpeciesReference

743144
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 12_C174H279N12O153S9
type: Species

825940
stoichiometry: 1.0
species: 735457
type: SpeciesReference

035215
product: 797566
product: 797542
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 797481
reactant: 797506
is: ENSCAFG00000009762.2
product: 797554
product: 797530
is: http://identifiers.org/ec-code/1.3.99.3
reversible: false
reactant: 797493
fast: false
type: Reaction
reactant: 797518
is: http://identifiers.org/ec-code/1.3.99.12
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2 R_ACOAD9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ACOAD9m equation: [m] : fad + ibcoa --> 2mp2coa + fadh2

763682
stoichiometry: 1.0
species: 740433
type: SpeciesReference

766979
stoichiometry: 1.0
species: 747686
type: SpeciesReference

769023
stoichiometry: 1.0
species: 746061
type: SpeciesReference

825350
stoichiometry: 1.0
species: 746521
type: SpeciesReference

726560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _17alpha-Hydroxyprogesterone_C21H30O3
type: Species

816777
stoichiometry: 1.0
species: 753676
type: SpeciesReference

819378
stoichiometry: 3.0
species: 749200
type: SpeciesReference

815933
stoichiometry: 1.0
species: 750141
type: SpeciesReference

816234
stoichiometry: 1.0
species: 741874
type: SpeciesReference

852135
stoichiometry: 1.0
species: 742843
type: SpeciesReference

843153
stoichiometry: 1.0
species: 740180
type: SpeciesReference

793822
stoichiometry: 1.0
species: 742333
type: SpeciesReference

822069
stoichiometry: 1.0
species: 733045
type: SpeciesReference

845547
stoichiometry: 1.0
species: 731755
type: SpeciesReference

773231
stoichiometry: 1.0
species: 737326
type: SpeciesReference

750309
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyridoxal 5'-phosphate_C8H8NO6P
type: Species

040320
product: 845523
reactant: 845511
notes: R_PHEMEt subsystem: Transport, Extracellular R_PHEMEt equation: pheme[e] --> pheme[c]
is: ENSCAFG00000018682.2
fast: false
reversible: false
name: heme transport
type: Reaction

846912
stoichiometry: 1.0
species: 743576
type: SpeciesReference

746786
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: de-Fuc, reducing GlcNAc removed, de-Sia, de-Gal form of PA6 (w/o peptide linkage)_C42H71N3O31
type: Species

844687
stoichiometry: 1.0
species: 744637
type: SpeciesReference

824566
stoichiometry: 1.0
species: 745146
type: SpeciesReference

759946
stoichiometry: 1.0
species: 741283
type: SpeciesReference

744510
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 7_C75H121N6O56SX
type: Species

825206
stoichiometry: 1.0
species: 741717
type: SpeciesReference

785031
stoichiometry: 2.0
species: 747746
type: SpeciesReference

745904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Malate_C4H4O5
type: Species

813615
stoichiometry: 1.0
species: 738618
type: SpeciesReference

855158
stoichiometry: 1.0
species: 730064
type: SpeciesReference

854605
stoichiometry: 3.0
species: 735216
type: SpeciesReference

818677
stoichiometry: 1.0
species: 744712
type: SpeciesReference

820352
stoichiometry: 1.0
species: 745699
type: SpeciesReference

773511
stoichiometry: 1.0
species: 739987
type: SpeciesReference

761998
stoichiometry: 1.0
species: 744611
type: SpeciesReference

729525
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: R total 2 position_CO2FULLR2
type: Species

767376
stoichiometry: 1.0
species: 746049
type: SpeciesReference

800219
stoichiometry: 2.0
species: 741344
type: SpeciesReference

745651
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

780290
stoichiometry: 1.0
species: 749322
type: SpeciesReference

753169
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: UDP_C9H11N2O12P2
type: Species

741983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Hydroxypyruvate_C3H3O4
type: Species

809434
stoichiometry: 1.0
species: 741259
type: SpeciesReference

793558
stoichiometry: 1.0
species: 742079
type: SpeciesReference

833098
stoichiometry: 2.0
species: 745579
type: SpeciesReference

840617
stoichiometry: 1.0
species: 750213
type: SpeciesReference

820040
stoichiometry: 1.0
species: 743276
type: SpeciesReference

800617
stoichiometry: 2.0
species: 746364
type: SpeciesReference

828917
stoichiometry: 2.0
species: 740023
type: SpeciesReference

827978
stoichiometry: 1.0
species: 730874
type: SpeciesReference

852953
stoichiometry: 1.0
species: 741018
type: SpeciesReference

827353
stoichiometry: 1.0
species: 748531
type: SpeciesReference

781686
stoichiometry: 1.0
species: 748699
type: SpeciesReference

734804
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4_C31H47NO35S3
type: Species

849671
stoichiometry: 1.0
species: 734477
type: SpeciesReference

817282
stoichiometry: 6.0
species: 741308
type: SpeciesReference

823032
stoichiometry: 1.0
species: 741259
type: SpeciesReference

746352
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: (R)-Mevalonate_C6H11O4
type: Species

821101
stoichiometry: 10.0
species: 741151
type: SpeciesReference

809108
stoichiometry: 1.0
species: 748687
type: SpeciesReference

842542
stoichiometry: 1.0
species: 730922
type: SpeciesReference

817995
stoichiometry: 12.0
species: 741151
type: SpeciesReference

764094
stoichiometry: 1.0
species: 740627
type: SpeciesReference

739692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: GDP_C10H12N5O11P2
type: Species

804454
stoichiometry: 1.0
species: 741621
type: SpeciesReference

782475
stoichiometry: 1.0
species: 742369
type: SpeciesReference

769155
stoichiometry: 4.0
species: 746918
type: SpeciesReference

756260
stoichiometry: 1.0
species: 750610
type: SpeciesReference

813917
stoichiometry: 4.0
species: 738292
type: SpeciesReference

760920
stoichiometry: 3.0
species: 748886
type: SpeciesReference

807772
stoichiometry: 1.0
species: 751446
type: SpeciesReference

031583
reactant: 764528
is: ENSCAFG00000010793.2
product: 764564
reactant: 764516
product: 764552
type: Reaction
notes: R_KCC2t subsystem: Transport, Extracellular R_KCC2t equation: cl[e] + nh4[e] <==> cl[c] + nh4[c] R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]
is: ENSCAFG00000020329.2
reversible: true
is: ENSCAFG00000007885.2
fast: false
reactant: 764540
product: 764576

776284
stoichiometry: 1.0
species: 730427
type: SpeciesReference

799040
stoichiometry: 2.0
species: 741151
type: SpeciesReference

741838
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
type: Species

845908
stoichiometry: 1.0
species: 729198
type: SpeciesReference

726864
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone_C58H88O3
type: Species

832448
stoichiometry: 1.0
species: 740723
type: SpeciesReference

749791
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: pristanal_C19H38O
type: Species

744157
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 6_C44H72N4O33SX
type: Species

768636
stoichiometry: 2.0
species: 741199
type: SpeciesReference

792715
stoichiometry: 1.0
species: 737642
type: SpeciesReference

731006
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ADPmannose_C16H23N5O15P2
type: Species

730789
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: O-Acetylcarnitine_C9H17NO4
type: Species

834144
stoichiometry: 1.0
species: 730076
type: SpeciesReference

830217
stoichiometry: 1.0
species: 734622
type: SpeciesReference

726717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _24R,25-Dihydroxyvitamin D3_C27H44O3
type: Species

036881
fast: false
modifier: 812493
modifier: 812457
modifier: 812505
reactant: 812373
reactant: 812361
product: 812397
type: Reaction
is: http://identifiers.org/ec-code/1.2.1.49
is: http://identifiers.org/ec-code/1.1.1.78
reactant: 812337
reactant: 812325
product: 812445
product: 812409
product: 812421
product: 812385
notes: R_ALCD22_D subsystem: Pyruvate Metabolism R_ALCD22_D equation: [c] : lald-D + nad --> h + mthgxl + nadh R_ALCD1 subsystem: Miscellaneous R_ALCD1 equation: [c] : meoh + nad <==> fald + h + nadh R_ALCD2if subsystem: Glycolysis/Gluconeogenesis R_ALCD2if equation: [c] : etoh + nad --> acald + h + nadh R_ALCD21_D subsystem: Pyruvate Metabolism R_ALCD21_D equation: [c] : 12ppd-R + nad --> h + lald-D + nadh R_ALCD22_L subsystem: Pyruvate Metabolism R_ALCD22_L equation: [c] : lald-L + nad --> h + mthgxl + nadh R_ALCD21_L subsystem: Pyruvate Metabolism R_ALCD21_L equation: [c] : 12ppd-S + nad --> h + lald-L + nadh
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modifier: 812469
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is: ENSCAFG00000000021.2
reactant: 812349
reversible: false
reactant: 812312
is: http://identifiers.org/ec-code/1.1.1.1

774041
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species: 741271
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species: 739099
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species: 753084
type: SpeciesReference

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species: 747454
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790210
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species: 739705
type: SpeciesReference

783680
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species: 731864
type: SpeciesReference

031693
reversible: false
product: 765368
type: Reaction
notes: R_HGNTOR subsystem: Tyrosine metabolism R_HGNTOR equation: [c] : hgentis + o2 --> 4mlacac + h
name: Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
is: http://identifiers.org/ec-code/1.13.11.5
reactant: 765343
product: 765380
fast: false
reactant: 765356
is: ENSCAFG00000011254.2

033475
fast: false
product: 781710
product: 781698
product: 781686
type: Reaction
notes: R_CEPTE subsystem: Glycerophospholipid Metabolism R_CEPTE equation: [c] : cdpea + dag_hs --> cmp + h + pe_hs R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs
product: 781674
reactant: 781662
reactant: 781650
is: ENSCAFG00000019766.2
reactant: 781638
reversible: false

855303
stoichiometry: 1.0
species: 741151
type: SpeciesReference

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boundary condition: false
has only substance units: false
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initial amount: NaN
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name: cervonyl carnitine_C29H45NO4
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828508
stoichiometry: 1.0
species: 732308
type: SpeciesReference

831282
stoichiometry: 1.0
species: 740518
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Dolichyl beta-D-glucosyl phosphate, human uterine homolog_C1085H1780O90P10
type: Species

843709
stoichiometry: 1.0
species: 744036
type: SpeciesReference

032511
product: 773957
reactant: 773908
product: 773944
type: Reaction
reversible: false
product: 773981
is: ENSCAFG00000001649.1
product: 773969
reactant: 773932
is: http://identifiers.org/ec-code/2.4.1.102
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE6GTg subsystem: O-Glycan Biosynthesis R_CORE6GTg equation: [g] : Tn_antigen + uacgam --> core6 + h + udp
fast: false
reactant: 773920

794634
stoichiometry: 1.0
species: 746352
type: SpeciesReference

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boundary condition: false
has only substance units: false
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initial amount: NaN
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name: (R)-Pantothenate_C9H16NO5
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775643
stoichiometry: 1.0
species: 727564
type: SpeciesReference

833808
stoichiometry: 1.0
species: 749031
type: SpeciesReference

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species: 742660
type: SpeciesReference

832508
stoichiometry: 1.0
species: 739766
type: SpeciesReference

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species: 744024
type: SpeciesReference

759087
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species: 741223
type: SpeciesReference

753700
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boundary condition: false
has only substance units: false
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initial amount: NaN
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825086
stoichiometry: 1.0
species: 729561
type: SpeciesReference

832232
stoichiometry: 1.0
species: 750695
type: SpeciesReference

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stoichiometry: 1.0
species: 739499
type: SpeciesReference

797518
stoichiometry: 3.0
species: 738039
type: SpeciesReference

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stoichiometry: 2.0
species: 741308
type: SpeciesReference

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stoichiometry: 1.0
species: 739815
type: SpeciesReference

830933
stoichiometry: 2.0
species: 741259
type: SpeciesReference

839413
stoichiometry: 1.0
species: 742103
type: SpeciesReference

782727
stoichiometry: 1.0
species: 736947
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
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initial amount: NaN
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name: Phosphate_HO4P
type: Species

819618
stoichiometry: 1.0
species: 744145
type: SpeciesReference

801747
stoichiometry: 2.0
species: 748206
type: SpeciesReference

783027
stoichiometry: 1.0
species: 744624
type: SpeciesReference

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stoichiometry: 1.0
species: 737822
type: SpeciesReference

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is: http://identifiers.org/ec-code/1.1.1.49
reactant: 785838
product: 785851
is: ENSCAFG00000019598.2
reversible: true
product: 785876
reactant: 785826
notes: R_G6PDH2r subsystem: Pentose Phosphate Pathway R_G6PDH2r equation: [c] : g6p + nadp <==> 6pgl + h + nadph
product: 785864
name: glucose 6-phosphate dehydrogenase
type: Reaction
fast: false

847704
stoichiometry: 1.0
species: 735228
type: SpeciesReference

781795
stoichiometry: 1.0
species: 726295
type: SpeciesReference

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stoichiometry: 1.0
species: 744000
type: SpeciesReference

801463
stoichiometry: 1.0
species: 742964
type: SpeciesReference

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species: 745904
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1720H2828N20O570P20
type: Species

754752
stoichiometry: 1.0
species: 742819
type: SpeciesReference

771601
stoichiometry: 1.0
species: 740970
type: SpeciesReference

797883
stoichiometry: 1.0
species: 745206
type: SpeciesReference

817174
stoichiometry: 1.0
species: 753786
type: SpeciesReference

767267
stoichiometry: 4.0
species: 732441
type: SpeciesReference

803652
stoichiometry: 1.0
species: 741223
type: SpeciesReference

809218
stoichiometry: 1.0
species: 746870
type: SpeciesReference

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constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I biosynthesis, precursor 17_C157H252N11O127S5X
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810663
stoichiometry: 2.0
species: 741259
type: SpeciesReference

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stoichiometry: 1.0
species: 745423
type: SpeciesReference

842750
stoichiometry: 3.0
species: 732441
type: SpeciesReference

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stoichiometry: 1.0
species: 748278
type: SpeciesReference

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species: 741572
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: L-Serine_C3H7NO3
type: Species

848934
stoichiometry: 1.0
species: 734816
type: SpeciesReference

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stoichiometry: 1.0
species: 730874
type: SpeciesReference

852508
stoichiometry: 1.0
species: 729465
type: SpeciesReference

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boundary condition: false
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initial amount: NaN
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816342
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species: 731791
type: SpeciesReference

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stoichiometry: 1.0
species: 729774
type: SpeciesReference

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stoichiometry: 1.0
species: 749358
type: SpeciesReference

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stoichiometry: 1.0
species: 751482
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: disialyl galactosylgloboside (homo sapiens)_C72H121N4O43FULLRCO
type: Species

768746
stoichiometry: 1.0
species: 741187
type: SpeciesReference

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stoichiometry: 1.0
species: 741826
type: SpeciesReference

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stoichiometry: 2.0
species: 741344
type: SpeciesReference

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stoichiometry: 1.0
species: 734902
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: DNA 5-methylcytosine_C11H19O8PR2
type: Species

770221
stoichiometry: 1.0
species: 738930
type: SpeciesReference

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stoichiometry: 1.0
species: 753314
type: SpeciesReference

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stoichiometry: 1.0
species: 753121
type: SpeciesReference

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modifier: 780844
is: http://identifiers.org/ec-code/4.2.1.17
product: 780747
product: 780675
is: http://identifiers.org/ec-code/1.3.99.3
notes: R_PRPNCOAHYDx subsystem: beta-Alanine metabolism R_PRPNCOAHYDx equation: [x] : h2o + prpncoa --> 3hpcoa R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_ECOAH1x subsystem: Tryptophan metabolism R_ECOAH1x equation: [x] : 3hbcoa <==> b2coa + h2o R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_FAOXC260240x subsystem: Fatty acid oxidation, peroxisome R_FAOXC260240x equation: [x] : coa + h2o + hexccoa + nad + o2 --> accoa + h + h2o2 + lgnccoa + nadh R_C2M26DCOAHLx subsystem: Limonene and pinene degradation R_C2M26DCOAHLx equation: [x] : c2m2…
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product: 780651
is: http://identifiers.org/ec-code/1.1.1.35
product: 780638
product: 780795
reactant: 780326
modifier: 780808
product: 780614
modifier: 780892
reactant: 780302
type: Reaction
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product: 780699
reactant: 780470
reactant: 780314
reactant: 780410
reactant: 780422
product: 780735
reactant: 780482
product: 780711
product: 780566
modifier: 780856
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reactant: 780494
is: ENSCAFG00000013218.2
modifier: 780868
reactant: 780506
reactant: 780518
reactant: 780350
product: 780783
reactant: 780386
reactant: 780362
product: 780602
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product: 780759
reactant: 780290
product: 780687
product: 780590
product: 780663
modifier: 780916
reactant: 780374
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reactant: 780398
product: 780723
product: 780626
product: 780554
reactant: 780542
modifier: 780880
reactant: 780458
reactant: 780434
modifier: 780820
reactant: 780530
reactant: 780446
modifier: 780832
product: 780771

792028
stoichiometry: 3.0
species: 741332
type: SpeciesReference

853506
stoichiometry: 1.0
species: 748302
type: SpeciesReference

753858
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: omega hydroxy tetradecanoate (n-C14:0)_C14H27O3
type: Species

761210
stoichiometry: 1.0
species: 741476
type: SpeciesReference

855412
stoichiometry: 1.0
species: 736704
type: SpeciesReference

806112
stoichiometry: 1.0
species: 737943
type: SpeciesReference

799196
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species: 734489
type: SpeciesReference

741500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Hexadecanoate (n-C16:0)_C16H31O2
type: Species

808289
stoichiometry: 1.0
species: 741283
type: SpeciesReference

762832
stoichiometry: 1.0
species: 742770
type: SpeciesReference

850935
stoichiometry: 4.0
species: 740675
type: SpeciesReference

733238
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2
type: Species

743588
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 7_C210H337N15O181S10
type: Species

731115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: adrenyl coenzyme A_C43H66N7O17P3S
type: Species

834253
stoichiometry: 1.0
species: 742868
type: SpeciesReference

835858
stoichiometry: 1.0
species: 744484
type: SpeciesReference

799569
stoichiometry: 1.0
species: 741066
type: SpeciesReference

727942
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4,8-Dihydroxyquinoline_C9H7NO2
type: Species

784635
stoichiometry: 1.0
species: 749538
type: SpeciesReference

811408
stoichiometry: 5.0
species: 731549
type: SpeciesReference

819727
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species: 744217
type: SpeciesReference

775535
stoichiometry: 1.0
species: 753121
type: SpeciesReference

833603
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species: 731477
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GM1alpha (homo sapiens)_C55H95N3O30FULLRCO
type: Species

763984
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species: 730148
type: SpeciesReference

820582
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species: 745459
type: SpeciesReference

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species: 730184
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species: 747209
type: SpeciesReference

797108
stoichiometry: 1.0
species: 743938
type: SpeciesReference

786774
stoichiometry: 1.0
species: 732188
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 2_C37H54NO37S2X
type: Species

754644
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species: 746978
type: SpeciesReference

790366
stoichiometry: 1.0
species: 753133
type: SpeciesReference

753059
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boundary condition: false
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name: Tyramine O-sulfate_C8H11NO4S
type: Species

774761
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species: 741332
type: SpeciesReference

744265
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 3_C47H76N4O33X
type: Species

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constant: false
boundary condition: false
has only substance units: false
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initial amount: NaN
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name: ATP_C10H12N5O13P3
type: Species

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product: 760896
fast: false
reversible: false
name: b-galactosidase, extracellular
reactant: 760860
is: ENSCAFG00000005126.2
is: http://identifiers.org/ec-code/3.2.1.23
reactant: 760872
product: 760884
notes: R_LACZe subsystem: Galactose metabolism R_LACZe equation: [e] : h2o + lcts --> gal + glc-D
type: Reaction

841052
stoichiometry: 1.0
species: 741416
type: SpeciesReference

791606
stoichiometry: 39.0
species: 730184
type: SpeciesReference

845087
stoichiometry: 1.0
species: 732441
type: SpeciesReference

795754
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species: 743841
type: SpeciesReference

791341
stoichiometry: 1.0
species: 736704
type: SpeciesReference

030633
reactant: 756260
product: 756309
type: Reaction
product: 756285
reactant: 756272
fast: false
is: ENSCAFG00000008031.2
reversible: true
name: retinol dehydrogenase (all-trans,NADPH)
is: http://identifiers.org/ec-code/1.1.1.105
notes: R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal
product: 756297

769920
stoichiometry: 1.0
species: 748266
type: SpeciesReference

735264
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: L-Cystathionine_C7H14N2O4S
type: Species

755092
stoichiometry: 1.0
species: 742055
type: SpeciesReference

036941
product: 813228
notes: R_HSD11B1r subsystem: Steroid Metabolism R_HSD11B1r equation: [r] : cortsn + h + nadph <==> crtsl + nadp
reversible: true
reactant: 813180
product: 813216
is: ENSCAFG00000011925.2
fast: false
name: _11-beta-hydroxysteroid dehydrogenase type 1
reactant: 813192
reactant: 813204
type: Reaction

038996
type: Reaction
reactant: 833338
is: ENSCAFG00000003624.2
product: 833362
reversible: false
is: http://identifiers.org/ec-code/3.1.3.66
reactant: 833326
name: inositol-3,4-bisphosphate 4-phosphatase
is: ENSCAFG00000024846.1
fast: false
product: 833350
notes: R_MI34PP subsystem: Inositol Phosphate Metabolism R_MI34PP equation: [c] : h2o + mi34p --> mi3p-D + pi

809977
stoichiometry: 1.0
species: 746449
type: SpeciesReference

750974
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initial amount: NaN
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name: Selenate_O4Se
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733642
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name: cholesterol sulfate_C27H45O4S
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834578
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species: 732441
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774362
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species: 741657
type: SpeciesReference

035155
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fast: false
product: 796708
notes: R_FAOXC183806m subsystem: Fatty acid oxidation R_FAOXC183806m equation: [m] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC161802m subsystem: Fatty acid activation R_FAOXC161802m equation: [m] : (4) coa + (3) fad + (4) h2o + hdd2coa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC160 subsystem: Fatty acid oxidation R_FAOXC160 equation: [m] : (7) coa + (7) fad + (7) h2o + (7) nad + pmtcoa --> (8) accoa + (7) fadh2 + (7) h + (7) nadh R_FAOXC2031836m subsystem: Fatty acid oxidation R_FAOXC2031836m equation: [m] : coa + dlnlcgcoa + fad + h2o + nad --> accoa + fadh2 + h + lnlncgcoa + nadh R_FAOXC80 subsystem: Fatty acid oxidation R_FAOXC80 equation: [m] : (3) coa + (3) fad + (3) h2o + (3) nad + occoa --> (4) accoa + (3) fadh2 + (3) h + (3) nadh R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_FAOXC2251836m subsystem: Fatty acid oxidation R_FAOXC2251836m equation: [m] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC18280m subsystem: Fatty acid oxidation R_FAOXC18280m equation: [m] : (5) coa + (3) fad + (5) h2o + lneldccoa + (5) nad --> (5) accoa + (3) fadh2 + (5) h + (5) nadh + occoa R_FAOXC16180m subsystem: Fatty acid oxidation R_FAOXC16180m equation: [m] : (4) coa + (3) fad + (4) h2o + hdcoa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC2051843m subsystem: Fatty acid oxidation R_FAOXC2051843m equation: [m] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC183803m subsystem: Fatty acid oxidation R_FAOXC183803m equation: [m] : (5) coa + (2) fad + (5) h2o + lnlncacoa + (5) nad --> (5) accoa + (2) fadh2 + (5) h + (5) nadh + occoa R_FAOXC2242046m subsystem: Fatty acid oxidation R_FAOXC2242046m equation: [m] : adrncoa + coa + fad + h2o + nad --> accoa + arachdcoa + fadh2 + h + nadh R_FAOXC200180m subsystem: Fatty acid oxidation R_FAOXC200180m equatio…
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reactant: 796537
reactant: 796549
type: Reaction
reactant: 796393
product: 796720
reactant: 796308
reactant: 796513
reactant: 796344
product: 796768
reactant: 796562
reactant: 796610
product: 796756
reactant: 796598
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product: 796842
product: 796732
reactant: 796574
reactant: 796477
reactant: 796405
reactant: 796369
reactant: 796417
reactant: 796635
reactant: 796441
reactant: 796622
reactant: 796453
product: 796794
is: ENSCAFG00000010446.2
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 796525
reactant: 796381
reactant: 796320
reactant: 796501
reactant: 796356
product: 796695
reactant: 796586
product: 796830
is: http://identifiers.org/ec-code/1.3.99.3
product: 796683
reactant: 796332
product: 796781
product: 796671

733581
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Cholesterol_C27H46O
type: Species

729319
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Cysteate_C3H6NO5S
type: Species

802688
stoichiometry: 1.0
species: 750707
type: SpeciesReference

747734
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: O2_O2
type: Species

763281
stoichiometry: 1.0
species: 736716
type: SpeciesReference

761441
stoichiometry: 1.0
species: 727142
type: SpeciesReference

736632
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: demethylated antipyrine_C10H10N2O
type: Species

805514
stoichiometry: 1.0
species: 744700
type: SpeciesReference

777641
stoichiometry: 1.0
species: 739656
type: SpeciesReference

832833
stoichiometry: 1.0
species: 738027
type: SpeciesReference

801040
stoichiometry: 1.0
species: 749466
type: SpeciesReference

844747
stoichiometry: 8.0
species: 741259
type: SpeciesReference

841389
stoichiometry: 1.0
species: 733606
type: SpeciesReference

814856
stoichiometry: 1.0
species: 728619
type: SpeciesReference

802121
stoichiometry: 1.0
species: 753266
type: SpeciesReference

808373
stoichiometry: 1.0
species: 734054
type: SpeciesReference

816005
stoichiometry: 1.0
species: 735745
type: SpeciesReference

850815
stoichiometry: 1.0
species: 754318
type: SpeciesReference

729883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH
type: Species

790594
stoichiometry: 1.0
species: 736061
type: SpeciesReference

816668
stoichiometry: 1.0
species: 735023
type: SpeciesReference

735373
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dADP_C10H12N5O9P2
type: Species

773667
stoichiometry: 1.0
species: 746291
type: SpeciesReference

794379
stoichiometry: 1.0
species: 729343
type: SpeciesReference

782366
stoichiometry: 1.0
species: 727795
type: SpeciesReference

756689
stoichiometry: 1.0
species: 733981
type: SpeciesReference

032967
reactant: 777555
type: Reaction
is: ENSCAFG00000025347.1
reactant: 777543
fast: false
name: protein lysine peptidase (endoplasmic reticulum)
is: ENSCAFG00000008927.2
notes: R_PLYSPSer subsystem: Lysine Metabolism R_PLYSPSer equation: [r] : Ntmelys + h2o --> pepslys + tmlys
product: 777567
reversible: false
is: ENSCAFG00000005457.2
is: ENSCAFG00000000100.2
product: 777579
is: ENSCAFG00000012889.2

849007
stoichiometry: 1.0
species: 743180
type: SpeciesReference

851689
stoichiometry: 5.0
species: 741151
type: SpeciesReference

783848
stoichiometry: 1.0
species: 729895
type: SpeciesReference

037399
product: 817850
type: Reaction
product: 817862
product: 817838
notes: R_TMDK1 subsystem: Nucleotides R_TMDK1 equation: [c] : atp + thymd --> adp + dtmp + h R_DURIK1 subsystem: Nucleotides R_DURIK1 equation: [c] : atp + duri --> adp + dump + h
reversible: false
product: 817874
is: ENSCAFG00000005294.2
reactant: 817802
reactant: 817826
fast: false
reactant: 817814
is: http://identifiers.org/ec-code/2.7.1.21

803980
stoichiometry: 1.0
species: 749213
type: SpeciesReference

764915
stoichiometry: 1.0
species: 742794
type: SpeciesReference

810025
stoichiometry: 1.0
species: 746497
type: SpeciesReference

845655
stoichiometry: 1.0
species: 736328
type: SpeciesReference

844531
stoichiometry: 1.0
species: 740812
type: SpeciesReference

810952
stoichiometry: 1.0
species: 754087
type: SpeciesReference

752926
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: testosterone sulfate_C19H27O5S
type: Species

745182
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Linoleyl carnitine_C25H45NO4
type: Species

750417
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ubiquinone-10_C59H90O4
type: Species

788337
stoichiometry: 2.0
species: 736231
type: SpeciesReference

728378
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,6-Dihydroxyindole-2-carboxylate_C9H6NO4
type: Species

752337
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,6,7,8-Tetrahydrofolate_C19H21N7O6
type: Species

760066
stoichiometry: 1.0
species: 748435
type: SpeciesReference

739987
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Glutamate_C5H8NO4
type: Species

736255
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Dehydroascorbate_C6H6O6
type: Species

033608
product: 782667
reactant: 782619
notes: R_N3Tg subsystem: O-Glycan Biosynthesis R_N3Tg equation: [g] : Tn_antigen + udpgal --> T_antigen + h + udp
product: 782643
is: http://identifiers.org/ec-code/2.4.1.122
reactant: 782631
product: 782655
name: N-acetylgalactosamine 3-beta-galactosyltransferase, Golgi apparatus
type: Reaction
is: ENSCAFG00000002227.2
reversible: false
fast: false

838301
stoichiometry: 1.0
species: 744736
type: SpeciesReference

791075
stoichiometry: 35.0
species: 741235
type: SpeciesReference

755164
stoichiometry: 1.0
species: 741259
type: SpeciesReference

855267
stoichiometry: 1.0
species: 732296
type: SpeciesReference

789313
stoichiometry: 1.0
species: 738015
type: SpeciesReference

030789
reactant: 757807
type: Reaction
product: 757832
reactant: 757795
fast: false
is: http://identifiers.org/ec-code/3.3.1.1
is: ENSCAFG00000001524.2
reversible: false
name: Se-Adenosylselenohomocysteine hydrolase
notes: R_SEAHCYSHYD subsystem: Selenoamino acid metabolism R_SEAHCYSHYD equation: [c] : h2o + seahcys --> adn + selhcys
product: 757820

818786
stoichiometry: 1.0
species: 748971
type: SpeciesReference

846318
stoichiometry: 1.0
species: 750562
type: SpeciesReference

827245
stoichiometry: 1.0
species: 746025
type: SpeciesReference

733431
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Choloyl-CoA_C45H70N7O20P3S
type: Species

729102
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _7-Dehydrocholesterol_C27H44O
type: Species

731876
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: androsterone glucuronide_C25H38O8
type: Species

824675
stoichiometry: 1.0
species: 749297
type: SpeciesReference

743036
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: ITP_C10H11N4O14P3
type: Species

778807
stoichiometry: 1.0
species: 732008
type: SpeciesReference

835063
stoichiometry: 1.0
species: 753254
type: SpeciesReference

780422
stoichiometry: 1.0
species: 751494
type: SpeciesReference

854484
stoichiometry: 3.0
species: 735216
type: SpeciesReference

766822
stoichiometry: 1.0
species: 746978
type: SpeciesReference

789711
stoichiometry: 1.0
species: 741777
type: SpeciesReference

036531
product: 809840
is: ENSCAFG00000015545.2
reactant: 809801
fast: false
reversible: false
type: Reaction
product: 809814
reactant: 809762
product: 809853
reactant: 809788
reactant: 809775
is: http://identifiers.org/ec-code/2.1.1.43
product: 809827
is: ENSCAFG00000004696.2
is: ENSCAFG00000004955.2
notes: R_LYSMTF3n subsystem: Lysine Metabolism R_LYSMTF3n equation: [n] : Ndmelys + amet --> Ntmelys + ahcys R_LYSMTF1n subsystem: Lysine Metabolism R_LYSMTF1n equation: [n] : amet + peplys --> Nmelys + ahcys R_LYSMTF2n subsystem: Lysine Metabolism R_LYSMTF2n equation: [n] : Nmelys + amet --> Ndmelys + ahcys
is: ENSCAFG00000016783.2
is: ENSCAFG00000019420.2
is: ENSCAFG00000003703.2
is: ENSCAFG00000004341.2
is: ENSCAFG00000015087.2
is: ENSCAFG00000019390.2
is: ENSCAFG00000007493.2

782090
stoichiometry: 1.0
species: 737919
type: SpeciesReference

763828
stoichiometry: 1.0
species: 735155
type: SpeciesReference

739111
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-D-Galactose 1-phosphate_C6H11O9P
type: Species

823008
stoichiometry: 1.0
species: 732441
type: SpeciesReference

819076
stoichiometry: 1.0
species: 747758
type: SpeciesReference

736849
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10
type: Species

772292
stoichiometry: 1.0
species: 743938
type: SpeciesReference

835401
stoichiometry: 1.0
species: 744447
type: SpeciesReference

747503
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Methylserotonin_C11H15N2O
type: Species

805273
stoichiometry: 1.0
species: 748699
type: SpeciesReference

734513
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1_C45H68N2O43S2
type: Species

780711
stoichiometry: 2.0
species: 749454
type: SpeciesReference

031355
product: 762844
reactant: 762711
reactant: 762784
reactant: 762651
product: 762931
product: 762870
reactant: 762735
reactant: 762687
product: 762992
reactant: 762639
reactant: 762832
product: 762882
reactant: 762675
product: 762894
fast: false
is: ENSCAFG00000018266.2
product: 762857
reactant: 762808
product: 762944
product: 762907
reactant: 762772
product: 762919
product: 763004
type: Reaction
product: 763016
product: 762980
product: 762956
reactant: 762723
product: 762968
reactant: 762627
reactant: 762820
reactant: 762796
reactant: 762663
reactant: 762747
reversible: false
product: 763053
reactant: 762699
notes: R_VALt4 subsystem: Transport, Extracellular R_VALt4 equation: na1[e] + val-L[e] --> na1[c] + val-L[c] R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_ILEt4 subsystem: Transport, Extracellular R_ILEt4 equation: ile-L[e] + na1[e] --> ile-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_HISt4 subsystem: Transport, Extracellular R_HISt4 equation: his-L[e] + na1[e] --> his-L[c] + na1[c] R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_TYRt4 subsystem: Transport, Extracellular R_TYRt4 equation: na1[e] + tyr-L[e] --> na1[c] + tyr-L[c] R_CYSt4 subsystem: Transport, Extracellular R_CYSt4 equation: cys-L[e] + na1[e] --> cys-L[c] + na1[c] R_ARGt4 subsystem: Transport, Extracellular R_ARGt4 equation: arg-L[e] + na1[e] --> arg-L[c] + na1[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_TRPt4 subsystem: Transport, Extracellular R_TRPt4 equation: na1[e] + trp-L[e] --> na1[c] + trp-L[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c] R_LYSt4 subsystem: Transport, Extracellular R_LYSt4 equation: lys-L[e] + na1[e] --> lys-L[c] + na1[c]
reactant: 762760
product: 763041
product: 763028

852736
stoichiometry: 1.0
species: 740071
type: SpeciesReference

797313
stoichiometry: 15.0
species: 741283
type: SpeciesReference

744856
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Leukotriene B4_C20H31O4
type: Species

831896
stoichiometry: 1.0
species: 733443
type: SpeciesReference

840087
stoichiometry: 1.0
species: 746978
type: SpeciesReference

774029
stoichiometry: 1.0
species: 730427
type: SpeciesReference

758230
stoichiometry: 1.0
species: 727034
type: SpeciesReference

814420
stoichiometry: 3.0
species: 746750
type: SpeciesReference

776819
stoichiometry: 1.0
species: 731453
type: SpeciesReference

841593
stoichiometry: 1.0
species: 750044
type: SpeciesReference

775763
stoichiometry: 5.0
species: 741428
type: SpeciesReference

751989
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S
type: Species

837664
stoichiometry: 4.0
species: 741259
type: SpeciesReference

816680
stoichiometry: 1.0
species: 735059
type: SpeciesReference

810459
stoichiometry: 1.0
species: 751808
type: SpeciesReference

768951
stoichiometry: 1.0
species: 739135
type: SpeciesReference

037690
modifier: 821859
fast: false
is: http://identifiers.org/ec-code/6.3.3.1
product: 821787
modifier: 821919
reactant: 821763
modifier: 821883
modifier: 821931
modifier: 821943
modifier: 821835
modifier: 821907
is: ENSCAFG00000009235.2
product: 821811
notes: R_GARFT subsystem: IMP Biosynthesis R_GARFT equation: [c] : 10fthf + gar <==> fgam + h + thf R_PRAGSr subsystem: IMP Biosynthesis R_PRAGSr equation: [c] : atp + gly + pram <==> adp + gar + h + pi R_PRAIS subsystem: IMP Biosynthesis R_PRAIS equation: [c] : atp + fpram --> adp + air + (2) h + pi
reactant: 821775
is: http://identifiers.org/ec-code/2.1.2.2
modifier: 821871
reversible: false
modifier: 821847
is: http://identifiers.org/ec-code/6.3.4.13
product: 821799
modifier: 821895
product: 821823
type: Reaction

744024
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 4_C101H165N7O72X
type: Species

763101
stoichiometry: 1.0
species: 734333
type: SpeciesReference

732152
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: arachidonic acid_C20H31O2
type: Species

782150
stoichiometry: 2.0
species: 749466
type: SpeciesReference

039815
is: ENSCAFG00000005020.2
notes: R_PCLAD subsystem: Tryptophan metabolism R_PCLAD equation: [c] : cmusa + h --> am6sa + co2
reactant: 841353
fast: false
is: http://identifiers.org/ec-code/4.1.1.45
name: picolinic acid decarboxylase
product: 841365
reactant: 841341
type: Reaction
product: 841377
reversible: false

853662
stoichiometry: 1.0
species: 741259
type: SpeciesReference

800630
stoichiometry: 2.0
species: 741332
type: SpeciesReference

757820
stoichiometry: 1.0
species: 751010
type: SpeciesReference

031741
product: 766184
product: 766400
reactant: 765704
product: 766280
product: 766340
reactant: 765877
product: 766146
reactant: 765952
reactant: 765915
product: 766171
reactant: 766000
product: 766436
product: 766268
product: 766208
product: 766256
reactant: 765729
reactant: 766037
reactant: 766012
reactant: 765765
reactant: 765790
product: 766412
reactant: 766049
reactant: 765803
product: 766244
reactant: 765864
product: 766110
reactant: 765976
product: 766232
notes: R_HEXCCPT2 subsystem: Carnitine shuttle R_HEXCCPT2 equation: [m] : coa + hexccrn --> crn + hexccoa R_C181CPT2 subsystem: Carnitine shuttle R_C181CPT2 equation: [m] : coa + odecrn --> crn + odecoa R_C160CPT2 subsystem: Carnitine shuttle R_C160CPT2 equation: [m] : coa + pmtcrn --> crn + pmtcoa R_RTOTALCRNCPT2 subsystem: Carnitine shuttle R_RTOTALCRNCPT2 equation: [m] : Rtotalcrn + coa --> Rtotalcoa + crn R_RTOTAL2CRNCPT2 subsystem: Carnitine shuttle R_RTOTAL2CRNCPT2 equation: [m] : Rtotal2crn + coa --> Rtotal2coa + crn R_VACCCPT2 subsystem: Carnitine shuttle R_VACCCPT2 equation: [m] : coa + vacccrn --> crn + vacccoa R_EICOSTETCPT2 subsystem: Carnitine shuttle R_EICOSTETCPT2 equation: [m] : coa + eicostetcrn --> crn + eicostetcoa R_TTDCPT2 subsystem: Carnitine shuttle R_TTDCPT2 equation: [m] : coa + ttdcrn --> crn + tdcoa R_PTDCACRNCPT2 subsystem: Carnitine shuttle R_PTDCACRNCPT2 equation: [m] : coa + ptdcacrn --> crn + ptdcacoa R_LGNCCPT2 subsystem: Carnitine shuttle R_LGNCCPT2 equation: [m] : coa + lgnccrn --> crn + lgnccoa R_C226CPT2 subsystem: Carnitine shuttle R_C226CPT2 equation: [m] : c226crn + coa --> c226coa + crn R_C161CPT22 subsystem: Carnitine shuttle R_C161CPT22 equation: [m] : coa + hdd2crn --> crn + hdd2coa R_DLNLCGCPT2 subsystem: Carnitine shuttle R_DLNLCGCPT2 equation: [m] : coa + dlnlcgcrn --> crn + dlnlcgcoa R_LNLCCPT2 subsystem: Carnitine shuttle R_LNLCCPT2 equation: [m] : coa + lnlccrn --> crn + lnlccoa R_CLPNDCPT2 subsystem: Carnitine shuttle R_CLPNDCPT2 equation: [m] : clpndcrn + coa --> clpndcoa + crn R_DCSPTN1CPT2 subsystem: Carnitine shuttle R_DCSPTN1CPT2 equation: [m] : coa + dcsptn1crn --> crn + dcsptn1coa R_HPDCACRNCPT2 subsystem: Carnitine shuttle R_HPDCACRNCPT2 equation: [m] : coa + hpdcacrn --> crn + hpdcacoa R_LNELDCCPT2 subsystem: Carnitine shuttle R_LNELDCCPT2 equation: [m] : coa + lneldccrn --> crn + lneldccoa R_STRDNCCPT2 subsystem: Carnitine shuttle R_STRDNCCPT2 equation: [m] : coa + strdnccrn --> crn + strdnccoa R_NRVNCCPT2 subsys…
reversible: false
reactant: 765815
reactant: 765692
reactant: 765902
fast: false
product: 766460
reactant: 765940
product: 766292
product: 766220
reactant: 765839
reactant: 765717
reactant: 765964
product: 766328
reactant: 765753
reactant: 766025
product: 766316
reactant: 766061
is: ENSCAFG00000019174.2
type: Reaction
product: 766073
reactant: 765668
reactant: 765889
reactant: 765988
product: 766388
product: 766097
product: 766304
reactant: 765827
product: 766472
reactant: 765927
product: 766376
reactant: 765656
product: 766424
reactant: 765741
product: 766364
product: 766085
product: 766134
product: 766448
product: 766196
reactant: 765778
product: 766122
reactant: 765851
product: 766159
product: 766352
reactant: 765680

848799
stoichiometry: 1.0
species: 743540
type: SpeciesReference

813494
stoichiometry: 1.0
species: 737678
type: SpeciesReference

754801
stoichiometry: 1.0
species: 732537
type: SpeciesReference

809749
stoichiometry: 4.0
species: 741151
type: SpeciesReference

740749
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Guanosine_C10H13N5O5
type: Species

032414
product: 772895
reactant: 772883
notes: R_ACGAMPM subsystem: Aminosugar Metabolism R_ACGAMPM equation: [c] : acgam6p <==> acgam1p
is: ENSCAFG00000002929.2
is: http://identifiers.org/ec-code/5.4.2.3
fast: false
reversible: true
name: phosphoacetylglucosamine mutase
type: Reaction

752617
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: N6,N6,N6-Trimethyl-L-lysine_C9H20N2O2
type: Species

773981
stoichiometry: 1.0
species: 734151
type: SpeciesReference

798078
stoichiometry: 1.0
species: 752157
type: SpeciesReference

749671
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pregnenolone_C21H32O2
type: Species

855593
stoichiometry: 2.0
species: 747294
type: SpeciesReference

737810
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: estrone glucuronide_C24H30O8
type: Species

829121
stoichiometry: 1.0
species: 732441
type: SpeciesReference

832520
stoichiometry: 3.0
species: 749466
type: SpeciesReference

817705
stoichiometry: 1.0
species: 746617
type: SpeciesReference

752764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Trehalose_C12H22O11
type: Species

824930
stoichiometry: 1.0
species: 741621
type: SpeciesReference

788661
stoichiometry: 1.0
species: 733981
type: SpeciesReference

746279
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Mesaconate_C5H4O4
type: Species

825507
stoichiometry: 1.0
species: 740168
type: SpeciesReference

767474
stoichiometry: 1.0
species: 745627
type: SpeciesReference

798186
stoichiometry: 1.0
species: 748121
type: SpeciesReference

810724
stoichiometry: 1.0
species: 742916
type: SpeciesReference

755816
stoichiometry: 1.0
species: 746978
type: SpeciesReference

764348
stoichiometry: 1.0
species: 747050
type: SpeciesReference

816572
stoichiometry: 1.0
species: 752557
type: SpeciesReference

737472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: ebastine_C32H39NO2
type: Species

847143
stoichiometry: 1.0
species: 743228
type: SpeciesReference

031246
fast: false
reactant: 761477
is: http://identifiers.org/ec-code/3.1.1.47
product: 761489
type: Reaction
is: ENSCAFG00000011135.1
product: 761513
reactant: 761465
product: 761501
reversible: false
name: Platelet-activating factor acetylhydrolase
notes: R_PAFHe subsystem: Glycerophospholipid Metabolism R_PAFHe equation: [e] : h2o + paf_hs --> ac + ak2lgchol_hs + h

826712
stoichiometry: 1.0
species: 739474
type: SpeciesReference

763269
stoichiometry: 1.0
species: 734127
type: SpeciesReference

812275
stoichiometry: 1.0
species: 753133
type: SpeciesReference

754003
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3alpha,7alpha,26-Trihydroxy-5beta-cholestane_C27H48O3
type: Species

783256
stoichiometry: 4.0
species: 741199
type: SpeciesReference

032210
reactant: 770777
product: 770950
reactant: 770803
fast: false
is: ENSCAFG00000024037.1
reactant: 770913
reactant: 770938
reactant: 770790
reactant: 770827
reactant: 770876
product: 771010
reactant: 770839
product: 770974
reactant: 770901
reactant: 770851
notes: R_DALAt2r subsystem: Transport, Extracellular R_DALAt2r equation: ala-D[e] + h[e] <==> ala-D[c] + h[c] R_ALAt2rL subsystem: Transport, Lysosomal R_ALAt2rL equation: ala-L[l] + h[l] <==> ala-L[c] + h[c] R_DALAt2rL subsystem: Transport, Lysosomal R_DALAt2rL equation: ala-D[l] + h[l] <==> ala-D[c] + h[c] R_ABUTt2r subsystem: Transport, Extracellular R_ABUTt2r equation: _4abut[e] + h[e] <==> 4abut[c] + h[c] R_PROt2r subsystem: Transport, Extracellular R_PROt2r equation: h[e] + pro-L[e] <==> h[c] + pro-L[c] R_ALAt2r subsystem: Transport, Extracellular R_ALAt2r equation: ala-L[e] + h[e] <==> ala-L[c] + h[c] R_GLYt2r subsystem: Transport, Extracellular R_GLYt2r equation: gly[e] + h[e] <==> gly[c] + h[c] R_PRODt2rL subsystem: Transport, Lysosomal R_PRODt2rL equation: h[l] + pro-D[l] <==> h[c] + pro-D[c] R_PROt2rL subsystem: Transport, Lysosomal R_PROt2rL equation: h[l] + pro-L[l] <==> h[c] + pro-L[c] R_PRODt2r subsystem: Transport, Extracellular R_PRODt2r equation: h[e] + pro-D[e] <==> h[c] + pro-D[c] R_ABUTt2rL subsystem: Transport, Lysosomal R_ABUTt2rL equation: _4abut[l] + h[l] <==> 4abut[c] + h[c] R_GLYt2rL subsystem: Transport, Lysosomal R_GLYt2rL equation: gly[l] + h[l] <==> gly[c] + h[c]
reactant: 770815
product: 771022
product: 770998
product: 770962
reactant: 770925
reactant: 770864
reversible: true
product: 770986
type: Reaction
reactant: 770888

850057
stoichiometry: 1.0
species: 727576
type: SpeciesReference

837640
stoichiometry: 1.0
species: 741368
type: SpeciesReference

738426
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide_C10H13N4O9P
type: Species

742904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: myo-Inositol_C6H12O6
type: Species

731706
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: S-Adenosyl-L-methionine_C15H23N6O5S
type: Species

772147
stoichiometry: 1.0
species: 743757
type: SpeciesReference

788000
stoichiometry: 1.0
species: 746038
type: SpeciesReference

779459
stoichiometry: 1.0
species: 731489
type: SpeciesReference

041154
product: 855146
type: Reaction
product: 855134
fast: false
reactant: 855122
product: 855170
reversible: false
notes: R_HMGLx subsystem: Cholesterol Metabolism R_HMGLx equation: [x] : hmgcoa --> acac + accoa R_HMGLm subsystem: Cholesterol Metabolism R_HMGLm equation: [m] : hmgcoa --> acac + accoa
is: ENSCAFG00000013085.2
is: http://identifiers.org/ec-code/4.1.3.4
reactant: 855110
product: 855158

784406
stoichiometry: 3.0
species: 747553
type: SpeciesReference

799774
stoichiometry: 1.0
species: 747294
type: SpeciesReference

787868
stoichiometry: 1.0
species: 742770
type: SpeciesReference

760394
stoichiometry: 1.0
species: 741259
type: SpeciesReference

849550
stoichiometry: 2.0
species: 743132
type: SpeciesReference

730076
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Acetaldehyde_C2H4O
type: Species

844760
stoichiometry: 1.0
species: 726912
type: SpeciesReference

727372
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
type: Species

770913
stoichiometry: 1.0
species: 731525
type: SpeciesReference

742382
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 1_C31H49NO25X
type: Species

036301
reactant: 808217
is: ENSCAFG00000001472.2
reactant: 808205
is: ENSCAFG00000014763.2
is: ENSCAFG00000004624.2
product: 808229
notes: R_CK subsystem: Urea cycle/amino group metabolism R_CK equation: [m] : atp + creat <==> adp + pcreat
product: 808241
is: ENSCAFG00000008641.2
is: ENSCAFG00000008707.2
is: ENSCAFG00000007001.2
fast: false
name: ATP Creatine kinase
reversible: true
is: http://identifiers.org/ec-code/2.7.3.2
is: ENSCAFG00000007401.2
type: Reaction

845391
stoichiometry: 2.0
species: 741163
type: SpeciesReference

791329
stoichiometry: 1.0
species: 752109
type: SpeciesReference

839281
stoichiometry: 1.0
species: 741344
type: SpeciesReference

797674
stoichiometry: 1.0
species: 730958
type: SpeciesReference

040465
name: phosphatidylinositol synthase (Homo sapiens)
product: 847341
reactant: 847293
is: http://identifiers.org/ec-code/2.7.8.11
reactant: 847305
product: 847317
product: 847329
type: Reaction
reversible: true
is: ENSCAFG00000016979.2
fast: false
notes: R_CDIPTr subsystem: Glycerophospholipid Metabolism R_CDIPTr equation: [c] : cdpdag_hs + inost <==> cmp + h + pail_hs

852833
stoichiometry: 1.0
species: 746461
type: SpeciesReference

821318
stoichiometry: 3.0
species: 741199
type: SpeciesReference

792474
stoichiometry: 1.0
species: 746049
type: SpeciesReference

761780
stoichiometry: 1.0
species: 752642
type: SpeciesReference

822081
stoichiometry: 5.0
species: 730922
type: SpeciesReference

777433
stoichiometry: 1.0
species: 744611
type: SpeciesReference

036712
product: 811168
is: http://identifiers.org/ec-code/3.6.1.6
reversible: false
product: 811144
reactant: 811132
product: 811156
is: ENSCAFG00000009139.2
fast: false
type: Reaction
name: nucleoside-diphosphatase (UDP), Golgi apparatus
reactant: 811120
notes: R_NDP7g subsystem: Nucleotides R_NDP7g equation: [g] : h2o + udp --> h + pi + ump

035985
fast: false
product: 805333
reactant: 805189
type: Reaction
product: 805261
reactant: 805201
product: 805309
product: 805321
reactant: 805225
notes: R_PCFLOPm subsystem: Transport, Mitochondrial R_PCFLOPm equation: atp[c] + h2o[c] + pchol_hs[m] --> adp[c] + h[c] + pchol_hs[c] + pi[c] R_PSFLIP subsystem: Transport, Extracellular R_PSFLIP equation: atp[c] + h2o[c] + ps_hs[e] --> adp[c] + h[c] + pi[c] + ps_hs[c] R_PEFLIP subsystem: Transport, Extracellular R_PEFLIP equation: atp[c] + h2o[c] + pe_hs[e] --> adp[c] + h[c] + pe_hs[c] + pi[c] R_PSFLIPm subsystem: Transport, Mitochondrial R_PSFLIPm equation: atp[c] + h2o[c] + ps_hs[c] --> adp[c] + h[c] + pi[c] + ps_hs[m] R_PEFLIPm subsystem: Transport, Mitochondrial R_PEFLIPm equation: atp[c] + h2o[c] + pe_hs[c] --> adp[c] + h[c] + pe_hs[m] + pi[c]
is: ENSCAFG00000010085.2
product: 805345
reactant: 805213
product: 805297
reversible: false
reactant: 805177
reactant: 805237
product: 805273
product: 805285
reactant: 805249

827015
stoichiometry: 1.0
species: 732441
type: SpeciesReference

034841
reactant: 793606
product: 793630
product: 793642
modifier: 793702
is: ENSCAFG00000018253.2
modifier: 793690
reactant: 793618
is: http://identifiers.org/ec-code/2.1.2.1
modifier: 793678
modifier: 793654
fast: false
modifier: 793666
reversible: false
notes: R_GHMT3 subsystem: Lysine Metabolism R_GHMT3 equation: [c] : 3htmelys + h --> 4tmeabut + gly R_GHMT2r subsystem: Glycine, Serine, and Threonine Metabolism R_GHMT2r equation: [c] : ser-L + thf <==> gly + h2o + mlthf
type: Reaction

756458
stoichiometry: 1.0
species: 737798
type: SpeciesReference

840774
stoichiometry: 1.0
species: 751482
type: SpeciesReference

762591
stoichiometry: 1.0
species: 753133
type: SpeciesReference

762446
stoichiometry: 1.0
species: 737798
type: SpeciesReference

836146
stoichiometry: 2.0
species: 741332
type: SpeciesReference

821739
stoichiometry: 1.0
species: 747294
type: SpeciesReference

789940
stoichiometry: 1.0
species: 745061
type: SpeciesReference

788890
stoichiometry: 1.0
species: 737266
type: SpeciesReference

844483
stoichiometry: 1.0
species: 740825
type: SpeciesReference

851020
stoichiometry: 2.0
species: 746617
type: SpeciesReference

836411
stoichiometry: 1.0
species: 730028
type: SpeciesReference

811264
stoichiometry: 1.0
species: 746521
type: SpeciesReference

788240
stoichiometry: 1.0
species: 736255
type: SpeciesReference

781945
stoichiometry: 1.0
species: 741151
type: SpeciesReference

796284
stoichiometry: 1.0
species: 733618
type: SpeciesReference

778964
stoichiometry: 1.0
species: 749091
type: SpeciesReference

808914
stoichiometry: 1.0
species: 739741
type: SpeciesReference

740898
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Oxidized glutathione_C20H30N6O12S2
type: Species

830765
stoichiometry: 1.0
species: 748326
type: SpeciesReference

736425
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dIDP_C10H11N4O10P2
type: Species

781084
stoichiometry: 3.0
species: 731718
type: SpeciesReference

838765
stoichiometry: 1.0
species: 741151
type: SpeciesReference

752049
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetracosapentaenoyl carnitine_C31H51NO4
type: Species

731441
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _2-Oxoglutarate_C5H4O5
type: Species

837243
stoichiometry: 1.0
species: 731852
type: SpeciesReference

837940
stoichiometry: 2.0
species: 739815
type: SpeciesReference

747650
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nervonyl carnitine_C31H59NO4
type: Species

813784
stoichiometry: 1.0
species: 750008
type: SpeciesReference

750733
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: PA6_C90H145N6O65X
type: Species

735035
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5a_C45H64N2O51S5X
type: Species

842960
stoichiometry: 1.0
species: 741259
type: SpeciesReference

807603
stoichiometry: 31.0
species: 741259
type: SpeciesReference

816897
stoichiometry: 1.0
species: 741259
type: SpeciesReference

773379
stoichiometry: 2.0
species: 741259
type: SpeciesReference

793246
stoichiometry: 1.0
species: 745651
type: SpeciesReference

032847
fast: false
name: glutaminase (mitochondrial)
is: ENSCAFG00000009513.2
product: 776734
is: ENSCAFG00000000131.2
notes: R_GLUNm subsystem: Glutamate metabolism R_GLUNm equation: [m] : gln-L + h2o --> glu-L + nh4
reactant: 776710
product: 776722
reactant: 776698
reversible: false
is: http://identifiers.org/ec-code/3.5.1.2
type: Reaction

826025
stoichiometry: 1.0
species: 733189
type: SpeciesReference

761671
stoichiometry: 1.0
species: 740651
type: SpeciesReference

849236
stoichiometry: 1.0
species: 737967
type: SpeciesReference

778215
stoichiometry: 1.0
species: 741259
type: SpeciesReference

742043
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 14_C57H84N3O62S5
type: Species

828604
stoichiometry: 1.0
species: 739522
type: SpeciesReference

037810
reactant: 822839
reactant: 822851
is: http://identifiers.org/ec-code/3.1.1.1
type: Reaction
notes: R_COKECBESr subsystem: Alkaloid biosynthesis II R_COKECBESr equation: [r] : coke + h2o --> bz + egme + h
product: 822875
fast: false
product: 822887
product: 822863
name: Carboxylesterase (cocaine) (er)
is: ENSCAFG00000020391.2
reversible: false

817547
stoichiometry: 2.0
species: 753157
type: SpeciesReference

742272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 8_C69H100N4O81S8
type: Species

727636
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3
type: Species

788565
stoichiometry: 1.0
species: 747553
type: SpeciesReference

772737
stoichiometry: 1.0
species: 727588
type: SpeciesReference

831606
stoichiometry: 1.0
species: 736825
type: SpeciesReference

730184
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Acetyl-CoA_C23H34N7O17P3S
type: Species

038767
type: Reaction
reactant: 831450
product: 831534
reactant: 831462
reactant: 831414
reversible: false
product: 831510
reactant: 831438
product: 831498
product: 831522
product: 831474
is: ENSCAFG00000000255.2
fast: false
is: http://identifiers.org/ec-code/2.4.1.92
product: 831486
notes: R_GALGT3 subsystem: Sphingolipid Metabolism R_GALGT3 equation: [g] : gd3_hs + udpacgal --> gd2_hs + h + udp R_GALGT2 subsystem: Sphingolipid Metabolism R_GALGT2 equation: [g] : gm3_hs + udpacgal --> gm2_hs + h + udp R_GALGT4 subsystem: Sphingolipid Metabolism R_GALGT4 equation: [g] : gt3_hs + udpacgal --> gt2_hs + h + udp R_GALGT1 subsystem: Sphingolipid Metabolism R_GALGT1 equation: [g] : galgluside_hs + udpacgal --> ga2_hs + h + udp
reactant: 831426

826171
stoichiometry: 1.0
species: 736971
type: SpeciesReference

774132
stoichiometry: 1.0
species: 739414
type: SpeciesReference

036519
is: ENSCAFG00000016019.2
reactant: 809701
product: 809749
product: 809713
reactant: 809676
reversible: false
product: 809725
reactant: 809651
is: http://identifiers.org/ec-code/1.14.19.1
notes: R_DESAT20_1 subsystem: Fatty acid elongation R_DESAT20_1 equation: [c] : dlnlcgcoa + h + nadh + o2 --> arachdcoa + (2) h2o + nad R_DESAT20_2 subsystem: Fatty acid elongation R_DESAT20_2 equation: [c] : eicostetcoa + h + nadh + o2 --> (2) h2o + nad + tmndnccoa
reactant: 809664
is: ENSCAFG00000025083.1
type: Reaction
fast: false
product: 809737
reactant: 809688

786629
stoichiometry: 1.0
species: 750538
type: SpeciesReference

776915
stoichiometry: 1.0
species: 744784
type: SpeciesReference

769590
stoichiometry: 2.0
species: 741283
type: SpeciesReference

751530
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H112O56
type: Species

806665
stoichiometry: 1.0
species: 727190
type: SpeciesReference

851237
stoichiometry: 1.0
species: 751434
type: SpeciesReference

736315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dehydroepiandrosterone sulfate_C19H27O5S
type: Species

806773
stoichiometry: 1.0
species: 741259
type: SpeciesReference

777156
stoichiometry: 5.0
species: 748651
type: SpeciesReference

760187
stoichiometry: 1.0
species: 748266
type: SpeciesReference

803073
stoichiometry: 1.0
species: 742588
type: SpeciesReference

728161
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: trans-4-Hydroxy-L-proline_C5H9NO3
type: Species

806905
stoichiometry: 2.0
species: 741271
type: SpeciesReference

800099
stoichiometry: 1.0
species: 737907
type: SpeciesReference

036869
product: 812300
is: ENSCAFG00000016423.2
is: http://identifiers.org/ec-code/2.4.1.198
reversible: false
is: ENSCAFG00000009702.2
reactant: 812251
is: ENSCAFG00000014703.2
name: phosphatidylinositol N-acetylglucosaminyltransferase
product: 812275
is: ENSCAFG00000019662.2
reactant: 812263
type: Reaction
product: 812288
fast: false
is: ENSCAFG00000011932.2
notes: R_PIACGT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_PIACGT equation: [c] : pail_hs + uacgam --> acgpail_hs + h + udp

851569
stoichiometry: 1.0
species: 747173
type: SpeciesReference

792583
stoichiometry: 1.0
species: 730148
type: SpeciesReference

852292
stoichiometry: 1.0
species: 744928
type: SpeciesReference

758799
stoichiometry: 6.0
species: 741416
type: SpeciesReference

751397
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Sphingosine 1-phosphate_C18H37NO5P
type: Species

772847
stoichiometry: 3.0
species: 746930
type: SpeciesReference

852941
stoichiometry: 5.0
species: 730958
type: SpeciesReference

753591
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Uridine_C9H12N2O6
type: Species

853398
stoichiometry: 1.0
species: 749478
type: SpeciesReference

843383
stoichiometry: 1.0
species: 746146
type: SpeciesReference

818919
stoichiometry: 1.0
species: 741259
type: SpeciesReference

727263
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-3-Amino-isobutanoate_C4H9NO2
type: Species

033913
reactant: 784971
reversible: false
notes: R_DHDPBMTm subsystem: Ubiquinone Biosynthesis R_DHDPBMTm equation: [m] : 3dpdhb + amet --> 3dpdhb_me + ahcys + h R_COQ3m subsystem: Ubiquinone Biosynthesis R_COQ3m equation: [m] : 2dpmhobq + amet --> ahcys + h + q10
product: 784995
product: 784983
reactant: 784947
reactant: 784959
fast: false
product: 785019
type: Reaction
product: 785007
is: ENSCAFG00000003469.2

727528
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Iodo-L-tyrosine_C9H10INO3
type: Species

788457
stoichiometry: 1.0
species: 739377
type: SpeciesReference

811156
stoichiometry: 1.0
species: 749225
type: SpeciesReference

819292
stoichiometry: 1.0
species: 729883
type: SpeciesReference

038028
is: ENSCAFG00000000387.2
type: Reaction
fast: false
product: 825868
notes: R_FRUt1r subsystem: Transport, Extracellular R_FRUt1r equation: fru[e] <==> fru[c] R_GALt1r subsystem: Transport, Extracellular R_GALt1r equation: gal[e] <==> gal[c] R_GAMt1r subsystem: Transport, Extracellular R_GAMt1r equation: gam[e] <==> gam[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c] R_MANt1r subsystem: Transport, Extracellular R_MANt1r equation: man[e] <==> man[c]
product: 825844
reactant: 825796
product: 825880
product: 825856
reactant: 825772
reactant: 825820
product: 825832
reactant: 825808
reactant: 825784
reversible: true

034733
is: ENSCAFG00000003665.2
reactant: 792655
reversible: false
type: Reaction
name: L-glutamate secretion via secretory vesicle (ATP driven)
fast: false
notes: R_GLUVESSEC subsystem: Transport, Extracellular R_GLUVESSEC equation: atp[c] + glu-L[c] + h2o[c] --> adp[c] + glu-L[e] + h[c] + pi[c]
is: ENSCAFG00000010093.2
is: ENSCAFG00000006786.2
reactant: 792631
product: 792679
reactant: 792643
product: 792667
product: 792691
product: 792703

816464
stoichiometry: 10.0
species: 749237
type: SpeciesReference

737362
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dUTP_C9H11N2O14P3
type: Species

777216
stoichiometry: 5.0
species: 741259
type: SpeciesReference

819148
stoichiometry: 1.0
species: 727190
type: SpeciesReference

793138
stoichiometry: 2.0
species: 745711
type: SpeciesReference

035445
fast: false
reversible: false
notes: R_GPIMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIMTer_L equation: [r] : (0.1) dolmanp_L + gacpail_hs --> (0.1) dolp_L + h + mgacpail_hs R_GPIMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIMTer_U equation: [r] : (0.1) dolmanp_U + gacpail_hs --> (0.1) dolp_U + h + mgacpail_hs
is: ENSCAFG00000013050.2
product: 800605
product: 800617
reactant: 800581
product: 800630
is: ENSCAFG00000011865.2
reactant: 800569
product: 800593
type: Reaction
reactant: 800556

037496
type: Reaction
fast: false
product: 819040
reversible: false
reactant: 819016
is: ENSCAFG00000017165.2
is: http://identifiers.org/ec-code/2.7.4.2
name: phosphomevalonate kinase
product: 819052
reactant: 819028
notes: R_PMEVKx subsystem: Cholesterol Metabolism R_PMEVKx equation: [x] : 5pmev + atp --> 5dpmev + adp

827125
stoichiometry: 1.0
species: 727360
type: SpeciesReference

757553
stoichiometry: 2.0
species: 747148
type: SpeciesReference

803218
stoichiometry: 2.0
species: 741259
type: SpeciesReference

038549
reactant: 829890
type: Reaction
is: ENSCAFG00000011454.2
notes: R_CYSGLYex subsystem: Transport, Extracellular R_CYSGLYex equation: cys-L[c] + gly[e] --> cys-L[e] + gly[c]
reversible: false
fast: false
name: L-cysteine/glycine exchanger
product: 829926
reactant: 829902
product: 829914

789831
stoichiometry: 1.0
species: 748507
type: SpeciesReference

830657
stoichiometry: 1.0
species: 739987
type: SpeciesReference

781120
stoichiometry: 1.0
species: 729441
type: SpeciesReference

728015
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4-Aminobutanoate_C4H9NO2
type: Species

801305
stoichiometry: 1.0
species: 730052
type: SpeciesReference

801028
stoichiometry: 1.0
species: 741259
type: SpeciesReference

778324
stoichiometry: 1.0
species: 742843
type: SpeciesReference

854024
stoichiometry: 1.0
species: 752740
type: SpeciesReference

757613
stoichiometry: 2.0
species: 754331
type: SpeciesReference

839859
stoichiometry: 1.0
species: 745711
type: SpeciesReference

038172
reactant: 826942
reversible: false
product: 826967
type: Reaction
fast: false
name: Phosphoenolpyruvate carboxykinase (GTP)
notes: R_PEPCKm subsystem: Glycolysis/Gluconeogenesis R_PEPCKm equation: [m] : gtp + oaa --> co2 + gdp + pep
product: 826979
is: http://identifiers.org/ec-code/4.1.1.32
product: 826991
is: ENSCAFG00000011868.2
reactant: 826955

748194
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: D-Ornithine_C5H13N2O2
type: Species

835954
stoichiometry: 1.0
species: 727190
type: SpeciesReference

810303
stoichiometry: 1.0
species: 749466
type: SpeciesReference

813893
stoichiometry: 3.0
species: 735445
type: SpeciesReference

750842
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: sialyl-Tn antigen_C19H30N2O13X
type: Species

853374
stoichiometry: 1.0
species: 732793
type: SpeciesReference

729750
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total carnitine_CO2FULLRC7H14NO2
type: Species

738027
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Flavin adenine dinucleotide oxidized_C27H31N9O15P2
type: Species

845208
stoichiometry: 1.0
species: 747294
type: SpeciesReference

764600
stoichiometry: 1.0
species: 741259
type: SpeciesReference

772424
stoichiometry: 1.0
species: 743697
type: SpeciesReference

797421
stoichiometry: 1.0
species: 743829
type: SpeciesReference

849344
stoichiometry: 2.0
species: 734779
type: SpeciesReference

846052
stoichiometry: 1.0
species: 729114
type: SpeciesReference

828712
stoichiometry: 1.0
species: 736291
type: SpeciesReference

817439
stoichiometry: 1.0
species: 741308
type: SpeciesReference

795406
stoichiometry: 1.0
species: 736243
type: SpeciesReference

746038
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Mannose 1-phosphate_C6H11O9P
type: Species

738858
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C70H117N2O55X
type: Species

032739
type: Reaction
is: ENSCAFG00000002939.2
reversible: true
product: 775775
notes: R_3HCO3_NAt subsystem: Transport, Extracellular R_3HCO3_NAt equation: (3) hco3[e] + na1[e] <==> (3) hco3[c] + na1[c] R_2HCO3_NAt subsystem: Transport, Extracellular R_2HCO3_NAt equation: (2) hco3[e] + na1[e] <==> (2) hco3[c] + na1[c]
reactant: 775763
product: 775787
fast: false
is: ENSCAFG00000024704.1
is: ENSCAFG00000008684.2
reactant: 775751

841485
stoichiometry: 1.0
species: 751651
type: SpeciesReference

842852
stoichiometry: 1.0
species: 745856
type: SpeciesReference

810519
stoichiometry: 1.0
species: 729919
type: SpeciesReference

802265
stoichiometry: 2.0
species: 741199
type: SpeciesReference

802470
stoichiometry: 2.0
species: 731273
type: SpeciesReference

790666
stoichiometry: 1.0
species: 736559
type: SpeciesReference

831715
stoichiometry: 1.0
species: 738087
type: SpeciesReference

038658
product: 830825
product: 830753
product: 830837
reactant: 830729
product: 830765
product: 830801
reactant: 830693
type: Reaction
is: ENSCAFG00000015246.2
fast: false
product: 830813
reactant: 830681
reversible: false
product: 830777
reactant: 830717
is: http://identifiers.org/ec-code/3.1.4.4
product: 830789
reactant: 830741
product: 830849
notes: R_PCHOLPg_hs subsystem: Glycerophospholipid Metabolism R_PCHOLPg_hs equation: [g] : h2o + pchol_hs --> chol + h + pa_hs R_PCHOLPr_hs subsystem: Glycerophospholipid Metabolism R_PCHOLPr_hs equation: [r] : h2o + pchol_hs --> chol + h + pa_hs R_PCHOLPm_hs subsystem: Glycerophospholipid Metabolism R_PCHOLPm_hs equation: [m] : h2o + pchol_hs --> chol + h + pa_hs
reactant: 830705

763548
stoichiometry: 1.0
species: 734005
type: SpeciesReference

039406
reactant: 837832
is: ENSCAFG00000013439.2
reactant: 837856
fast: false
is: ENSCAFG00000018237.2
is: ENSCAFG00000023850.1
product: 837964
reactant: 837844
is: ENSCAFG00000013498.2
product: 837928
type: Reaction
product: 837940
reactant: 837892
product: 837952
reactant: 837868
reactant: 837880
product: 837916
reversible: true
notes: R_H2Ot subsystem: Transport, Extracellular R_H2Ot equation: h2o[e] <==> h2o[c] R_UREAt5 subsystem: Transport, Extracellular R_UREAt5 equation: h2o[e] + urea[e] <==> h2o[c] + urea[c] R_GLCt4_2 subsystem: Transport, Extracellular R_GLCt4_2 equation: glc-D[e] + (2) na1[e] <==> glc-D[c] + (2) na1[c] R_GLCt2_2 subsystem: Transport, Extracellular R_GLCt2_2 equation: glc-D[e] + (2) h[e] <==> glc-D[c] + (2) h[c] R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c] R_GALt2_2 subsystem: Transport, Extracellular R_GALt2_2 equation: gal[e] + (2) h[e] <==> gal[c] + (2) h[c] R_GALt4_2 subsystem: Transport, Extracellular R_GALt4_2 equation: gal[e] + (2) na1[e] <==> gal[c] + (2) na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
product: 837904

804887
stoichiometry: 1.0
species: 741959
type: SpeciesReference

834691
stoichiometry: 1.0
species: 728378
type: SpeciesReference

823562
stoichiometry: 10.0
species: 733213
type: SpeciesReference

762931
stoichiometry: 1.0
species: 746291
type: SpeciesReference

747319
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Ammonium_H4N
type: Species

770570
stoichiometry: 1.0
species: 748808
type: SpeciesReference

848077
stoichiometry: 1.0
species: 741705
type: SpeciesReference

039274
is: ENSCAFG00000010386.2
reversible: false
fast: false
product: 836677
type: Reaction
product: 836653
product: 836640
is: http://identifiers.org/ec-code/2.4.99.4
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1
reactant: 836616
reactant: 836604
product: 836665
reactant: 836628

814577
stoichiometry: 6.0
species: 747099
type: SpeciesReference

728908
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

847402
stoichiometry: 1.0
species: 741259
type: SpeciesReference

031897
product: 767690
fast: false
reactant: 767594
reactant: 767606
reversible: true
reactant: 767642
reactant: 767630
is: ENSCAFG00000016277.2
notes: R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad R_HACD9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_HACD9m equation: [m] : 3hmbcoa + nad <==> 2maacoa + h + nadh
reactant: 767618
product: 767702
product: 767654
is: http://identifiers.org/ec-code/1.1.1.35
type: Reaction
product: 767666
product: 767678

756032
stoichiometry: 1.0
species: 751263
type: SpeciesReference

838169
stoichiometry: 1.0
species: 741151
type: SpeciesReference

754548
stoichiometry: 1.0
species: 742055
type: SpeciesReference

771058
stoichiometry: 1.0
species: 740518
type: SpeciesReference

783547
stoichiometry: 1.0
species: 749055
type: SpeciesReference

744964
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

792895
stoichiometry: 1.0
species: 737067
type: SpeciesReference

726137
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

852400
stoichiometry: 6.0
species: 746930
type: SpeciesReference

800520
stoichiometry: 1.0
species: 731429
type: SpeciesReference

829277
stoichiometry: 1.0
species: 746521
type: SpeciesReference

812385
stoichiometry: 2.0
species: 746750
type: SpeciesReference

774496
stoichiometry: 1.0
species: 740385
type: SpeciesReference

733021
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Carbamoyl-beta-alanine_C4H7N2O3
type: Species

786364
stoichiometry: 1.0
species: 747026
type: SpeciesReference

757404
stoichiometry: 22.0
species: 741139
type: SpeciesReference

757006
stoichiometry: 1.0
species: 752037
type: SpeciesReference

832677
stoichiometry: 3.0
species: 730536
type: SpeciesReference

749562
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6
type: Species

039104
reactant: 834445
is: ENSCAFG00000013897.2
type: Reaction
product: 834506
reactant: 834421
reactant: 834397
notes: R_DCYTD subsystem: Pyrimidine Catabolism R_DCYTD equation: [c] : dcyt + h + h2o --> duri + nh4 R_CYTDn subsystem: Nucleotides R_CYTDn equation: [n] : cytd + h + h2o --> nh4 + uri R_DCYTDn subsystem: Nucleotides R_DCYTDn equation: [n] : dcyt + h + h2o --> duri + nh4 R_CYTD subsystem: Pyrimidine Catabolism R_CYTD equation: [c] : cytd + h + h2o --> nh4 + uri
product: 834481
reactant: 834469
reactant: 834457
product: 834493
reversible: false
reactant: 834433
is: http://identifiers.org/ec-code/3.5.4.14
product: 834518
product: 834530
reactant: 834385
reactant: 834409
fast: false
product: 834542
is: http://identifiers.org/ec-code/3.5.4.5

831330
stoichiometry: 1.0
species: 741283
type: SpeciesReference

758122
stoichiometry: 3.0
species: 733933
type: SpeciesReference

031138
name: adenylate cyclase
fast: false
reversible: false
is: ENSCAFG00000012084.2
is: http://identifiers.org/ec-code/4.6.1.1
is: ENSCAFG00000009913.2
type: Reaction
is: ENSCAFG00000008907.2
notes: R_ADNCYC subsystem: Nucleotides R_ADNCYC equation: [c] : atp --> camp + ppi
is: ENSCAFG00000004090.2
product: 760835
is: ENSCAFG00000010238.2
is: ENSCAFG00000012293.2
is: ENSCAFG00000001097.2
is: ENSCAFG00000015387.2
product: 760847
reactant: 760823
is: ENSCAFG00000024479.1

031463
is: http://identifiers.org/ec-code/3.2.1.10
fast: false
product: 763707
is: ENSCAFG00000025518.1
notes: R_O16G1e subsystem: Starch and Sucrose Metabolism R_O16G1e equation: [e] : glygn4 + h2o --> glc-D + glygn5 R_SUCRe subsystem: Galactose metabolism R_SUCRe equation: [e] : h2o + sucr --> fru + glc-D R_O16G2e subsystem: Starch and Sucrose Metabolism R_O16G2e equation: [e] : h2o + strch2 --> glc-D + malt
is: ENSCAFG00000014397.2
product: 763719
reactant: 763694
reactant: 763658
reactant: 763682
is: http://identifiers.org/ec-code/3.2.1.26
product: 763743
reactant: 763670
reversible: false
product: 763731
type: Reaction

754958
stoichiometry: 12.0
species: 747050
type: SpeciesReference

778734
stoichiometry: 16.0
species: 739827
type: SpeciesReference

761343
stoichiometry: 1.0
species: 741283
type: SpeciesReference

806039
stoichiometry: 1.0
species: 747319
type: SpeciesReference

817102
stoichiometry: 1.0
species: 739256
type: SpeciesReference

782631
stoichiometry: 1.0
species: 729858
type: SpeciesReference

757977
stoichiometry: 2.0
species: 751687
type: SpeciesReference

852628
stoichiometry: 2.0
species: 734005
type: SpeciesReference

739522
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: glycocholate_C26H43NO6
type: Species

745302
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: gamma-linolenyl carnitine_C25H43NO4
type: Species

800955
stoichiometry: 1.0
species: 732441
type: SpeciesReference

777890
stoichiometry: 2.0
species: 739196
type: SpeciesReference

759390
stoichiometry: 1.0
species: 741259
type: SpeciesReference

797746
stoichiometry: 1.0
species: 747613
type: SpeciesReference

826869
stoichiometry: 1.0
species: 729598
type: SpeciesReference

785596
stoichiometry: 1.0
species: 732441
type: SpeciesReference

779567
stoichiometry: 1.0
species: 730741
type: SpeciesReference

832004
stoichiometry: 8.0
species: 746930
type: SpeciesReference

764239
stoichiometry: 1.0
species: 741259
type: SpeciesReference

788770
stoichiometry: 5.0
species: 747002
type: SpeciesReference

732080
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Arachidic acid_C20H39O2
type: Species

823454
stoichiometry: 3.0
species: 741006
type: SpeciesReference

798800
stoichiometry: 9.0
species: 735373
type: SpeciesReference

825616
stoichiometry: 1.0
species: 751470
type: SpeciesReference

804743
stoichiometry: 1.0
species: 745170
type: SpeciesReference

754111
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: cholesterol ester_C27H45XCO2
type: Species

764649
stoichiometry: 1.0
species: 748910
type: SpeciesReference

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stoichiometry: 4.0
species: 741416
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Melanin_C9H6NO4
type: Species

768843
stoichiometry: 1.0
species: 752842
type: SpeciesReference

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stoichiometry: 1.0
species: 746291
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (trimannosyl),(phosphoethanolaminyl)-mannosyl-glucosaminyl-acylphosphatidylinositol (M4C)_C57H104N2O37P2FULLRCO2FULLR2CO2
type: Species

824807
stoichiometry: 1.0
species: 752157
type: SpeciesReference

792196
stoichiometry: 1.0
species: 742357
type: SpeciesReference

849441
stoichiometry: 2.0
species: 743168
type: SpeciesReference

756104
stoichiometry: 1.0
species: 742720
type: SpeciesReference

799665
stoichiometry: 1.0
species: 750309
type: SpeciesReference

848185
stoichiometry: 2.0
species: 747221
type: SpeciesReference

827534
stoichiometry: 1.0
species: 752962
type: SpeciesReference

738317
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Folate_C19H18N7O6
type: Species

779700
stoichiometry: 1.0
species: 747902
type: SpeciesReference

842338
stoichiometry: 2.0
species: 746086
type: SpeciesReference

749899
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: L-Proline_C5H9NO2
type: Species

039128
is: ENSCAFG00000011437.2
is: ENSCAFG00000024030.1
is: ENSCAFG00000023735.1
is: ENSCAFG00000024889.1
notes: R_DCT subsystem: Tyrosine metabolism R_DCT equation: [c] : L-dpchrm <==> 56dihindlcrbxlt
product: 834691
type: Reaction
reactant: 834678
name: Dopachrome tautomerase
reversible: true
is: ENSCAFG00000023677.1
is: http://identifiers.org/ec-code/5.3.3.12
fast: false
is: ENSCAFG00000025281.1

807543
stoichiometry: 1.0
species: 744637
type: SpeciesReference

769360
stoichiometry: 3.0
species: 729234
type: SpeciesReference

740325
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Glycerol_C3H8O3
type: Species

753399
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: UMP_C9H11N2O9P
type: Species

809664
stoichiometry: 1.0
species: 737533
type: SpeciesReference

805381
stoichiometry: 1.0
species: 747698
type: SpeciesReference

767582
stoichiometry: 2.0
species: 741259
type: SpeciesReference

838613
stoichiometry: 1.0
species: 731597
type: SpeciesReference

843166
stoichiometry: 1.0
species: 752496
type: SpeciesReference

040765
notes: R_TCHOLAt2 subsystem: Transport, Extracellular R_TCHOLAt2 equation: (2) na1[e] + tchola[e] --> (2) na1[c] + tchola[c] R_GCHOLAt2 subsystem: Transport, Extracellular R_GCHOLAt2 equation: gchola[e] + (2) na1[e] --> gchola[c] + (2) na1[c] R_CHOLATEt2 subsystem: Transport, Extracellular R_CHOLATEt2 equation: cholate[e] + (2) na1[e] --> cholate[c] + (2) na1[c]
product: 851966
reactant: 851906
product: 851991
reactant: 851930
is: ENSCAFG00000006008.2
type: Reaction
fast: false
reversible: false
product: 851978
product: 851954
reactant: 851942
reactant: 851918

035371
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/3.6.1.7
notes: R_ACYP subsystem: Glycolysis/Gluconeogenesis R_ACYP equation: [c] : 13dpg + h2o --> 3pg + h + pi
product: 799991
is: ENSCAFG00000017020.2
is: ENSCAFG00000023070.1
product: 800003
fast: false
is: ENSCAFG00000002938.2
reactant: 799967
name: acylphosphatase
product: 799979
reactant: 799955

789519
stoichiometry: 2.0
species: 732441
type: SpeciesReference

851785
stoichiometry: 5.0
species: 741259
type: SpeciesReference

743156
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 13_C174H280N12O150S8
type: Species

799329
stoichiometry: 1.0
species: 746930
type: SpeciesReference

728233
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4 hydroxy tolbutamide_C12H18N2O4S
type: Species

753435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: UMP_C9H11N2O9P
type: Species

852148
stoichiometry: 1.0
species: 735457
type: SpeciesReference

728776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Methylthio-5-deoxy-D-ribose 1-phosphate_C6H11O7PS
type: Species

836568
stoichiometry: 1.0
species: 727624
type: SpeciesReference

784851
stoichiometry: 1.0
species: 742431
type: SpeciesReference

854340
stoichiometry: 1.0
species: 748375
type: SpeciesReference

803375
stoichiometry: 1.0
species: 738003
type: SpeciesReference

769011
stoichiometry: 1.0
species: 736243
type: SpeciesReference

815945
stoichiometry: 1.0
species: 744904
type: SpeciesReference

757771
stoichiometry: 2.0
species: 741259
type: SpeciesReference

726572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _18 hydroxy arachidonic acid_C20H31O3
type: Species

816789
stoichiometry: 1.0
species: 732477
type: SpeciesReference

816246
stoichiometry: 1.0
species: 731549
type: SpeciesReference

819366
stoichiometry: 1.0
species: 750321
type: SpeciesReference

815196
stoichiometry: 2.0
species: 749514
type: SpeciesReference

035227
reactant: 797578
reversible: true
reactant: 797590
product: 797650
is: http://identifiers.org/ec-code/2.7.1.107
is: ENSCAFG00000009248.2
is: ENSCAFG00000003373.2
product: 797674
product: 797638
reactant: 797614
reactant: 797602
fast: false
notes: R_DAGK_hs subsystem: Glycerophospholipid Metabolism R_DAGK_hs equation: [c] : atp + dag_hs <==> adp + h + pa_hs R_DAGKn_hs subsystem: Glycerophospholipid Metabolism R_DAGKn_hs equation: [n] : atp + dag_hs <==> adp + h + pa_hs
product: 797686
product: 797662
product: 797626
type: Reaction

841269
stoichiometry: 1.0
species: 749200
type: SpeciesReference

765889
stoichiometry: 1.0
species: 745001
type: SpeciesReference

763694
stoichiometry: 3.0
species: 741163
type: SpeciesReference

744522
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 8_C83H134N7O61SX
type: Species

845535
stoichiometry: 1.0
species: 732441
type: SpeciesReference

846900
stoichiometry: 1.0
species: 743432
type: SpeciesReference

844699
stoichiometry: 1.0
species: 730028
type: SpeciesReference

746798
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41
type: Species

824554
stoichiometry: 1.0
species: 736583
type: SpeciesReference

759958
stoichiometry: 1.0
species: 735409
type: SpeciesReference

793810
stoichiometry: 2.0
species: 748663
type: SpeciesReference

742491
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate proteoglycan_C79H113N5O101S12X
type: Species

849779
stoichiometry: 1.0
species: 734489
type: SpeciesReference

739802
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: D-glucurono-6,3-lactone_C6H8O6
type: Species

820364
stoichiometry: 1.0
species: 736922
type: SpeciesReference

789615
stoichiometry: 1.0
species: 746243
type: SpeciesReference

825363
stoichiometry: 1.0
species: 746473
type: SpeciesReference

773523
stoichiometry: 1.0
species: 744784
type: SpeciesReference

813047
stoichiometry: 1.0
species: 747050
type: SpeciesReference

821209
stoichiometry: 1.0
species: 727540
type: SpeciesReference

034300
is: ENSCAFG00000011762.2
is: ENSCAFG00000002077.2
reactant: 788661
name: carboxylic acid dissociation
is: ENSCAFG00000008702.2
fast: false
is: http://identifiers.org/ec-code/4.2.1.1
is: ENSCAFG00000025237.1
product: 788685
is: ENSCAFG00000020399.2
is: ENSCAFG00000008676.2
notes: R_H2CO3D subsystem: Miscellaneous R_H2CO3D equation: [c] : co2 + h2o <==> h2co3
reactant: 788673
type: Reaction
reversible: true
is: ENSCAFG00000016990.2

735697
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: docosa-4,7,10,13,16-pentaenoyl carnitine_C29H47NO4
type: Species

818689
stoichiometry: 11.0
species: 747002
type: SpeciesReference

037279
reversible: false
is: ENSCAFG00000009093.2
notes: R_BHMT subsystem: Glycine, Serine, and Threonine Metabolism R_BHMT equation: [c] : glyb + hcys-L --> dmgly + met-L
type: Reaction
reactant: 816596
product: 816620
name: betaine-homocysteine S-methyltransferase
is: http://identifiers.org/ec-code/2.1.1.5
is: ENSCAFG00000009102.2
product: 816608
reactant: 816584
fast: false

847848
stoichiometry: 2.0
species: 751058
type: SpeciesReference

771360
stoichiometry: 1.0
species: 749249
type: SpeciesReference

813603
stoichiometry: 1.0
species: 738594
type: SpeciesReference

825218
stoichiometry: 1.0
species: 745170
type: SpeciesReference

783728
stoichiometry: 1.0
species: 753543
type: SpeciesReference

816149
stoichiometry: 1.0
species: 741886
type: SpeciesReference

735793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-dodecenoyl CoA_C33H52N7O17P3S
type: Species

038876
name: phosphogluconate dehydrogenase
product: 832232
is: ENSCAFG00000016797.2
is: http://identifiers.org/ec-code/1.1.1.44
reversible: false
type: Reaction
reactant: 832208
fast: false
reactant: 832220
product: 832256
notes: R_GND subsystem: Pentose Phosphate Pathway R_GND equation: [c] : 6pgc + nadp --> co2 + nadph + ru5p-D
product: 832244

824288
stoichiometry: 1.0
species: 742407
type: SpeciesReference

780566
stoichiometry: 1.0
species: 749322
type: SpeciesReference

823780
stoichiometry: 6.0
species: 741428
type: SpeciesReference

850719
stoichiometry: 1.0
species: 750902
type: SpeciesReference

791221
stoichiometry: 1.0
species: 727722
type: SpeciesReference

844047
stoichiometry: 1.0
species: 744546
type: SpeciesReference

805418
stoichiometry: 1.0
species: 727492
type: SpeciesReference

738183
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Fe2+_Fe
type: Species

750032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Prostaglandin E2_C20H31O5
type: Species

851128
stoichiometry: 2.0
species: 738243
type: SpeciesReference

779182
stoichiometry: 1.0
species: 739039
type: SpeciesReference

815666
stoichiometry: 1.0
species: 742382
type: SpeciesReference

735143
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA) proteoglycan_C45H63N2O54S6X
type: Species

037062
modifier: 814158
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/2.7.7.18
modifier: 814133
modifier: 814121
product: 814049
is: http://identifiers.org/ec-code/2.7.7.1
reactant: 814001
product: 814061
reactant: 814013
reactant: 814025
product: 814073
reactant: 814037
modifier: 814085
notes: R_NMNATm subsystem: NAD Metabolism R_NMNATm equation: [m] : atp + h + nmn --> nad + ppi R_NNATm subsystem: NAD Metabolism R_NNATm equation: [m] : atp + h + nicrnt --> dnad + ppi R_NNATr subsystem: NAD Metabolism R_NNATr equation: [c] : atp + h + nicrnt <==> dnad + ppi R_NMNATr subsystem: NAD Metabolism R_NMNATr equation: [c] : atp + h + nmn <==> nad + ppi
modifier: 814109
modifier: 814146
fast: false
modifier: 814097
is: ENSCAFG00000007624.2

832953
stoichiometry: 2.0
species: 745663
type: SpeciesReference

793522
stoichiometry: 4.0
species: 741187
type: SpeciesReference

736111
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dihydroxyacetone phosphate_C3H5O6P
type: Species

812239
stoichiometry: 1.0
species: 742988
type: SpeciesReference

734963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 6_C31H48NO32S2
type: Species

810880
stoichiometry: 1.0
species: 753157
type: SpeciesReference

790883
stoichiometry: 1.0
species: 746990
type: SpeciesReference

752483
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Threonine_C4H9NO3
type: Species

791967
stoichiometry: 1.0
species: 748886
type: SpeciesReference

851350
stoichiometry: 1.0
species: 746978
type: SpeciesReference

039935
product: 842013
reactant: 841977
product: 842001
is: ENSCAFG00000013700.2
notes: R_2OXOADPTm subsystem: Tryptophan metabolism R_2OXOADPTm equation: _2oxoadp[c] + akg[m] <==> 2oxoadp[m] + akg[c] R_2AMADPTm subsystem: Lysine Metabolism R_2AMADPTm equation: L2aadp[c] + akg[m] <==> L2aadp[m] + akg[c]
product: 841989
type: Reaction
reactant: 841953
reversible: true
reactant: 841965
fast: false

783475
stoichiometry: 1.0
species: 736135
type: SpeciesReference

728884
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

796586
stoichiometry: 103.0
species: 734091
type: SpeciesReference

806389
stoichiometry: 4.0
species: 741296
type: SpeciesReference

834787
stoichiometry: 6.0
species: 741259
type: SpeciesReference

849127
stoichiometry: 1.0
species: 743396
type: SpeciesReference

736535
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dITP_C10H11N4O13P3
type: Species

843938
stoichiometry: 1.0
species: 743926
type: SpeciesReference

032306
reversible: false
is: http://identifiers.org/ec-code/1.11.1.7
product: 771661
is: ENSCAFG00000017456.2
reactant: 771637
fast: false
notes: R_PRDX subsystem: Miscellaneous R_PRDX equation: [c] : h2o2 + meoh --> fald + (2) h2o
product: 771673
type: Reaction
name: Peroxidase (multiple substrates)
reactant: 771649

762022
stoichiometry: 1.0
species: 750381
type: SpeciesReference

853218
stoichiometry: 1.0
species: 741259
type: SpeciesReference

777372
stoichiometry: 1.0
species: 728982
type: SpeciesReference

848643
stoichiometry: 1.0
species: 734963
type: SpeciesReference

786088
stoichiometry: 1.0
species: 741753
type: SpeciesReference

801185
stoichiometry: 9.0
species: 746918
type: SpeciesReference

765464
stoichiometry: 1.0
species: 749200
type: SpeciesReference

762711
stoichiometry: 1.0
species: 744796
type: SpeciesReference

783692
stoichiometry: 1.0
species: 731900
type: SpeciesReference

790222
stoichiometry: 1.0
species: 742745
type: SpeciesReference

768624
stoichiometry: 2.0
species: 749466
type: SpeciesReference

744145
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 5_C50H82N4O38SX
type: Species

792703
stoichiometry: 1.0
species: 741259
type: SpeciesReference

736959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10
type: Species

830229
stoichiometry: 5.0
species: 741187
type: SpeciesReference

835737
stoichiometry: 1.0
species: 743817
type: SpeciesReference

730777
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: O-Acetylcarnitine_C9H17NO4
type: Species

834132
stoichiometry: 1.0
species: 739486
type: SpeciesReference

804041
stoichiometry: 2.0
species: 741259
type: SpeciesReference

764794
stoichiometry: 1.0
species: 747099
type: SpeciesReference

726704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _24R,25-Dihyoxyvitamin D2_C28H44O3
type: Species

032523
reversible: false
product: 774029
type: Reaction
name: beta-mannosidase, lysosomal
fast: false
is: ENSCAFG00000010769.2
reactant: 774005
is: http://identifiers.org/ec-code/3.2.1.25
product: 774017
notes: R_B_MANNASEly subsystem: N-Glycan Degradation R_B_MANNASEly equation: [l] : h2o + mn --> acgam + man
reactant: 773993

836291
stoichiometry: 1.0
species: 753278
type: SpeciesReference

794622
stoichiometry: 2.0
species: 747148
type: SpeciesReference

761561
stoichiometry: 1.0
species: 753495
type: SpeciesReference

831294
stoichiometry: 1.0
species: 745387
type: SpeciesReference

732937
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: cervonyl coenzyme A_C43H62N7O17P3S
type: Species

808169
stoichiometry: 1.0
species: 747528
type: SpeciesReference

794031
stoichiometry: 1.0
species: 747698
type: SpeciesReference

797205
stoichiometry: 1.0
species: 743697
type: SpeciesReference

747878
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO
type: Species

039707
reactant: 840195
notes: R_LSTO1r subsystem: Cholesterol Metabolism R_LSTO1r equation: [r] : chlstol + h + nadph + o2 --> ddsmsterol + (2) h2o + nadp R_LSTO2r subsystem: Cholesterol Metabolism R_LSTO2r equation: [r] : h + lthstrl + nadph + o2 --> 7dhchsterol + (2) h2o + nadp
reactant: 840171
reactant: 840147
is: ENSCAFG00000011805.1
product: 840231
product: 840207
type: Reaction
product: 840243
reactant: 840183
reactant: 840159
is: http://identifiers.org/ec-code/1.3.3.2
reversible: false
fast: false
product: 840219

743468
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I, degradation product 36_C62H103N4O49S1
type: Species

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product: 781553
product: 781626
is: http://identifiers.org/ec-code/3.6.1.9
reactant: 781456
reactant: 781493
reactant: 781505
product: 781589
is: ENSCAFG00000000001.2
reactant: 781517
is: http://identifiers.org/ec-code/2.7.7.18
product: 781565
type: Reaction
reactant: 781468
product: 781613
product: 781541
reactant: 781480
notes: R_UDPGP subsystem: Starch and Sucrose Metabolism R_UDPGP equation: [c] : h2o + udpg --> g1p + (2) h + ump R_NNAT subsystem: NAD Metabolism R_NNAT equation: [c] : atp + h + nicrnt --> dnad + ppi R_DNADDP subsystem: NAD Metabolism R_DNADDP equation: [c] : dnad + h2o --> amp + (2) h + nicrnt R_FADDP subsystem: Riboflavin Metabolism R_FADDP equation: [c] : fad + h2o --> amp + fmn + (2) h
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is: ENSCAFG00000000367.2
product: 781577
reversible: false
reactant: 781529

031681
reversible: false
fast: false
is: ENSCAFG00000018753.2
is: ENSCAFG00000005861.2
notes: R_NADH2_DASH_u10m subsystem: Oxidative Phosphorylation R_NADH2_DASH_u10m equation: (5) h[m] + nadh[m] + q10[m] --> (4) h[c] + nad[m] + q10h2[m]
is: ENSCAFG00000010193.2
is: http://identifiers.org/ec-code/1.6.99.3
is: ENSCAFG00000008411.2
is: ENSCAFG00000018686.2
is: ENSCAFG00000012591.2
type: Reaction
is: ENSCAFG00000014244.2
is: ENSCAFG00000016258.2
is: ENSCAFG00000017259.2
is: ENSCAFG00000010508.2
is: ENSCAFG00000001045.2
is: ENSCAFG00000020282.2
is: ENSCAFG00000003134.2
is: ENSCAFG00000003185.2
is: ENSCAFG00000003930.2
is: ENSCAFG00000009698.2
reactant: 765269
is: ENSCAFG00000010903.2
is: ENSCAFG00000017667.2
product: 765319
is: ENSCAFG00000015306.1
is: ENSCAFG00000012850.2
is: ENSCAFG00000011083.2
is: ENSCAFG00000000982.2
product: 765331
product: 765307
reactant: 765282
name: NADH dehydrogenase, mitochondrial
is: ENSCAFG00000012111.2
is: ENSCAFG00000011204.2
is: ENSCAFG00000006232.2
is: ENSCAFG00000019476.2
is: ENSCAFG00000015320.2
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is: ENSCAFG00000011109.2
is: ENSCAFG00000004842.2
is: ENSCAFG00000018497.2
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reactant: 765295
is: ENSCAFG00000010444.2

775655
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species: 741308
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: (R)-Pantothenate_C9H16NO5
type: Species

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species: 728583
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: zymosterol intermediate 2_C27H42O
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species: 751542
type: SpeciesReference

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species: 738955
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species: 742260
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species: 731405
type: SpeciesReference

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species: 749707
type: SpeciesReference

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stoichiometry: 1.0
species: 753133
type: SpeciesReference

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species: 728982
type: SpeciesReference

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species: 738474
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Phosphate_HO4P
type: Species

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species: 732284
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species: 743204
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species: 731840
type: SpeciesReference

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species: 750454
type: SpeciesReference

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species: 732441
type: SpeciesReference

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stoichiometry: 1.0
species: 740361
type: SpeciesReference

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stoichiometry: 1.0
species: 751506
type: SpeciesReference

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stoichiometry: 1.0
species: 742843
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hydroxypyruvate_C3H3O4
type: Species

829494
stoichiometry: 1.0
species: 741259
type: SpeciesReference

833086
stoichiometry: 13.0
species: 746086
type: SpeciesReference

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stoichiometry: 1.0
species: 738015
type: SpeciesReference

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stoichiometry: 1.0
species: 743552
type: SpeciesReference

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stoichiometry: 1.0
species: 753713
type: SpeciesReference

729537
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total 2 coenzyme A_CO2FULLR2C21H31N7O15P3S
type: Species

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stoichiometry: 12.0
species: 741078
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
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type: Species

827341
stoichiometry: 1.0
species: 748591
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 5_C31H48NO32S2
type: Species

781698
stoichiometry: 1.0
species: 748847
type: SpeciesReference

798294
stoichiometry: 1.0
species: 732949
type: SpeciesReference

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stoichiometry: 1.0
species: 746918
type: SpeciesReference

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stoichiometry: 32.0
species: 753157
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _2-Decaprenyl-6-methoxy-1,4-benzoquinone_C57H86O3
type: Species

754440
stoichiometry: 1.0
species: 739486
type: SpeciesReference

828929
stoichiometry: 2.0
species: 728076
type: SpeciesReference

842554
stoichiometry: 1.0
species: 741259
type: SpeciesReference

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stoichiometry: 1.0
species: 732441
type: SpeciesReference

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stoichiometry: 1.0
species: 748121
type: SpeciesReference

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stoichiometry: 1.0
species: 734658
type: SpeciesReference

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stoichiometry: 2.0
species: 741151
type: SpeciesReference

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boundary condition: false
has only substance units: false
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initial amount: NaN
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name: (R)-Mevalonate_C6H11O4
type: Species

817270
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species: 747722
type: SpeciesReference

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stoichiometry: 1.0
species: 746918
type: SpeciesReference

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reversible: false
reactant: 850333
is: ENSCAFG00000014100.2
product: 850370
type: Reaction
is: http://identifiers.org/ec-code/4.1.2.27
product: 850382
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product: 850358
reactant: 850321
fast: false
product: 850394
reactant: 850345

731018
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: ADPribose 2'-phosphate_C15H20N5O17P3
type: Species

770790
stoichiometry: 1.0
species: 731513
type: SpeciesReference

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stoichiometry: 1.0
species: 743084
type: SpeciesReference

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stoichiometry: 11.0
species: 739680
type: SpeciesReference

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stoichiometry: 1.0
species: 746146
type: SpeciesReference

739680
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: GDP_C10H12N5O11P2
type: Species

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stoichiometry: 1.0
species: 746146
type: SpeciesReference

776272
stoichiometry: 1.0
species: 734537
type: SpeciesReference

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stoichiometry: 1.0
species: 731694
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
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initial amount: NaN
in compartment: 726113
type: Species

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reactant: 780241
product: 780253
product: 780278
type: Reaction
fast: false
notes: R_LPS4e subsystem: Triacylglycerol Synthesis R_LPS4e equation: [e] : h2o + pglyc_hs --> 1glyc_hs + Rtotal2 + h
is: ENSCAFG00000012981.2
reversible: false
product: 780265
reactant: 780229
name: phospholipase

853518
stoichiometry: 1.0
species: 741259
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: w hydroxy testosterone_C19H28O3
type: Species

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stoichiometry: 5.0
species: 746978
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Dimethylallyl diphosphate_C5H9O7P2
type: Species

799184
stoichiometry: 1.0
species: 734465
type: SpeciesReference

775306
stoichiometry: 1.0
species: 728571
type: SpeciesReference

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stoichiometry: 3.0
species: 747038
type: SpeciesReference

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stoichiometry: 1.0
species: 753278
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Acetamidobutanoate_C6H10NO3
type: Species

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stoichiometry: 1.0
species: 727239
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3
type: Species

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fast: false
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.143
reversible: false
product: 759922
notes: R_M16NTg subsystem: N-Glycan Biosynthesis R_M16NTg equation: [g] : nm2masn + uacgam --> h + n2m2masn + udp
product: 759946
product: 759934
name: alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
is: ENSCAFG00000007720.2
reactant: 759910
reactant: 759898

814843
stoichiometry: 1.0
species: 732441
type: SpeciesReference

794513
stoichiometry: 2.0
species: 747209
type: SpeciesReference

732695
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Bilirubin_C33H34N4O6
type: Species

731127
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: adrenyl coenzyme A_C43H66N7O17P3S
type: Species

823178
stoichiometry: 1.0
species: 731429
type: SpeciesReference

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stoichiometry: 1.0
species: 739208
type: SpeciesReference

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stoichiometry: 1.0
species: 740349
type: SpeciesReference

808277
stoichiometry: 1.0
species: 753157
type: SpeciesReference

762820
stoichiometry: 17.0
species: 746930
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 6_C210H336N15O184S11
type: Species

850923
stoichiometry: 1.0
species: 746146
type: SpeciesReference

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product: 764492
reversible: true
is: ENSCAFG00000019451.2
reactant: 764444
reactant: 764456
is: ENSCAFG00000008647.2
fast: false
notes: R_TKT2 subsystem: Pentose Phosphate Pathway R_TKT2 equation: [c] : e4p + xu5p-D <==> f6p + g3p R_TKT1 subsystem: Pentose Phosphate Pathway R_TKT1 equation: [c] : r5p + xu5p-D <==> g3p + s7p
product: 764480
product: 764504
reactant: 764468
is: http://identifiers.org/ec-code/2.2.1.1
type: Reaction

846198
stoichiometry: 1.0
species: 741259
type: SpeciesReference

800352
stoichiometry: 1.0
species: 730124
type: SpeciesReference

827810
stoichiometry: 4.0
species: 741416
type: SpeciesReference

820570
stoichiometry: 2.0
species: 741259
type: SpeciesReference

763972
stoichiometry: 1.0
species: 741826
type: SpeciesReference

839558
stoichiometry: 1.0
species: 748847
type: SpeciesReference

800207
stoichiometry: 1.0
species: 745928
type: SpeciesReference

784623
stoichiometry: 2.0
species: 741211
type: SpeciesReference

799557
stoichiometry: 1.0
species: 734005
type: SpeciesReference

037170
notes: R_AKR1D2 subsystem: Bile Acid Biosynthesis R_AKR1D2 equation: [c] : h + nadph + xoldiolone --> nadp + xoldioloneh R_AKR1D subsystem: Bile Acid Biosynthesis R_AKR1D equation: [c] : h + nadph + xol7aone --> nadp + xol7ah
product: 815557
reactant: 815533
reactant: 815521
product: 815569
is: ENSCAFG00000015184.2
type: Reaction
reversible: false
reactant: 815545
fast: false
product: 815581
reactant: 815509

819715
stoichiometry: 1.0
species: 744108
type: SpeciesReference

032631
fast: false
product: 774701
is: http://identifiers.org/ec-code/2.6.1.2
is: ENSCAFG00000003676.2
type: Reaction
reactant: 774676
reactant: 774689
product: 774713
reversible: true
is: ENSCAFG00000001648.2
name: L-alanine transaminase
notes: R_ALATA_L subsystem: Glutamate metabolism R_ALATA_L equation: [c] : akg + ala-L <==> glu-L + pyr

775547
stoichiometry: 1.0
species: 753157
type: SpeciesReference

841040
stoichiometry: 1.0
species: 741283
type: SpeciesReference

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stoichiometry: 3.0
species: 731549
type: SpeciesReference

797896
stoichiometry: 33.0
species: 734345
type: SpeciesReference

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stoichiometry: 1.0
species: 739865
type: SpeciesReference

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stoichiometry: 1.0
species: 741332
type: SpeciesReference

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stoichiometry: 1.0
species: 748085
type: SpeciesReference

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stoichiometry: 1.0
species: 737127
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate C (GalNAc6S-GlcA), free chain_C45H67N2O46S3
type: Species

754656
stoichiometry: 1.0
species: 746882
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II biosynthesis, precursor 2_C39H63N3O28X
type: Species

785488
stoichiometry: 1.0
species: 751010
type: SpeciesReference

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stoichiometry: 1.0
species: 752581
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: chenodeoxycholoyl coenzyme a_C45H70N7O19P3S
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Androsterone_C19H30O2
type: Species

783039
stoichiometry: 1.0
species: 739975
type: SpeciesReference

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stoichiometry: 4.0
species: 749200
type: SpeciesReference

808710
stoichiometry: 1.0
species: 748435
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: _3',8'-LD1_C66H111N4O38FULLRCO
type: Species

832304
stoichiometry: 1.0
species: 738943
type: SpeciesReference

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stoichiometry: 1.0
species: 733606
type: SpeciesReference

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stoichiometry: 2.0
species: 741332
type: SpeciesReference

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stoichiometry: 4.0
species: 753230
type: SpeciesReference

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stoichiometry: 1.0
species: 736123
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1665H2740N20O570P20
type: Species

810675
stoichiometry: 1.0
species: 736511
type: SpeciesReference

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stoichiometry: 1.0
species: 753955
type: SpeciesReference

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stoichiometry: 1.0
species: 728668
type: SpeciesReference

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stoichiometry: 1.0
species: 751094
type: SpeciesReference

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stoichiometry: 2.0
species: 732489
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 28_C213H341N15O176S8X
type: Species

816354
stoichiometry: 1.0
species: 753435
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 16_C157H253N11O124S4X
type: Species

827834
stoichiometry: 1.0
species: 751214
type: SpeciesReference

848946
stoichiometry: 82.0
species: 741187
type: SpeciesReference

848293
stoichiometry: 1.0
species: 735673
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: XTP_C10H11N4O15P3
type: Species

796356
stoichiometry: 1.0
species: 736595
type: SpeciesReference

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stoichiometry: 1.0
species: 747062
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2
type: Species

778518
stoichiometry: 1.0
species: 751771
type: SpeciesReference

766085
stoichiometry: 1.0
species: 732200
type: SpeciesReference

817850
stoichiometry: 2.0
species: 730922
type: SpeciesReference

804599
stoichiometry: 1.0
species: 729561
type: SpeciesReference

782354
stoichiometry: 1.0
species: 729307
type: SpeciesReference

032955
reactant: 777458
reactant: 777421
reversible: true
product: 777495
fast: false
reactant: 777409
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c]
reactant: 777445
reactant: 777397
product: 777482
product: 777531
product: 777519
product: 777507
product: 777470
is: ENSCAFG00000006054.2
reactant: 777433
type: Reaction

851677
stoichiometry: 1.0
species: 731876
type: SpeciesReference

849019
stoichiometry: 1.0
species: 734731
type: SpeciesReference

037387
reactant: 817644
reactant: 817681
product: 817730
type: Reaction
is: http://identifiers.org/ec-code/3.5.4.9
reactant: 817717
product: 817742
reactant: 817705
product: 817778
is: http://identifiers.org/ec-code/1.5.1.5
is: http://identifiers.org/ec-code/6.3.4.3
reactant: 817656
product: 817790
product: 817754
reactant: 817693
product: 817766
is: ENSCAFG00000000413.2
reactant: 817669
fast: false
notes: R_MTHFDm subsystem: Folate Metabolism R_MTHFDm equation: [m] : mlthf + nadp <==> methf + nadph R_FTHFLm subsystem: Folate Metabolism R_FTHFLm equation: [m] : atp + for + thf <==> 10fthf + adp + pi R_MTHFCm subsystem: Folate Metabolism R_MTHFCm equation: [m] : h2o + methf <==> 10fthf + h
reversible: true

839703
stoichiometry: 2.0
species: 745663
type: SpeciesReference

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stoichiometry: 1.0
species: 736777
type: SpeciesReference

767039
stoichiometry: 1.0
species: 741259
type: SpeciesReference

783836
stoichiometry: 1.0
species: 746013
type: SpeciesReference

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stoichiometry: 1.0
species: 744784
type: SpeciesReference

846028
stoichiometry: 1.0
species: 726187
type: SpeciesReference

756677
stoichiometry: 1.0
species: 741259
type: SpeciesReference

752914
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: testosterone glucuronide_C25H36O8
type: Species

810940
stoichiometry: 1.0
species: 745351
type: SpeciesReference

788349
stoichiometry: 1.0
species: 747099
type: SpeciesReference

745194
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-Linolenic acid, C18:3, n-3_C18H29O2
type: Species

750405
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Pyruvate_C3H3O3
type: Species

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stoichiometry: 1.0
species: 739877
type: SpeciesReference

810037
stoichiometry: 1.0
species: 733738
type: SpeciesReference

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stoichiometry: 18.0
species: 732441
type: SpeciesReference

844543
stoichiometry: 3.0
species: 733884
type: SpeciesReference

827233
stoichiometry: 1.0
species: 741308
type: SpeciesReference

808589
stoichiometry: 1.0
species: 731549
type: SpeciesReference

736267
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dehydroepiandrosterone_C19H28O2
type: Species

789301
stoichiometry: 1.0
species: 730922
type: SpeciesReference

791063
stoichiometry: 1.0
species: 744976
type: SpeciesReference

755176
stoichiometry: 1.0
species: 747173
type: SpeciesReference

032090
product: 769506
product: 769518
reactant: 769494
reactant: 769482
reactant: 769470
is: ENSCAFG00000010868.2
product: 769542
reactant: 769458
type: Reaction
fast: false
reversible: false
is: http://identifiers.org/ec-code/2.3.1.15
notes: R_GPAMm_hs subsystem: Triacylglycerol Synthesis R_GPAMm_hs equation: [m] : Rtotalcoa + glyc3p --> alpa_hs + coa R_GPAM_hs subsystem: Triacylglycerol Synthesis R_GPAM_hs equation: [c] : Rtotalcoa + glyc3p --> alpa_hs + coa
product: 769530

855279
stoichiometry: 1.0
species: 738822
type: SpeciesReference

030777
fast: false
notes: R_HSD3B13 subsystem: Steroid Metabolism R_HSD3B13 equation: [c] : 17ahprgnlone + nad --> 17ahprgstrn + h + nadh R_HSD3B11 subsystem: Steroid Metabolism R_HSD3B11 equation: [c] : nad + prgnlone --> h + nadh + prgstrn
reactant: 757723
product: 757747
product: 757783
reactant: 757711
product: 757771
reactant: 757735
reversible: false
product: 757759
is: ENSCAFG00000010039.2
type: Reaction

818798
stoichiometry: 1.0
species: 731489
type: SpeciesReference

039551
is: ENSCAFG00000014339.2
product: 838945
product: 838909
reactant: 838849
reactant: 838885
fast: false
type: Reaction
product: 838969
product: 838981
product: 838897
product: 838933
reversible: true
notes: R_GSNtl subsystem: Transport, Lysosomal R_GSNtl equation: gsn[l] <==> gsn[c] R_ADEtl subsystem: Transport, Lysosomal R_ADEtl equation: ade[l] <==> ade[c] R_INStl subsystem: Transport, Lysosomal R_INStl equation: ins[l] <==> ins[c] R_Uritl subsystem: Transport, Lysosomal R_Uritl equation: uri[l] <==> uri[c] R_THYMDtl subsystem: Transport, Lysosomal R_THYMDtl equation: thymd[l] <==> thymd[c] R_HXANtl subsystem: Transport, Lysosomal R_HXANtl equation: hxan[l] <==> hxan[c] R_CYTDtl subsystem: Transport, Lysosomal R_CYTDtl equation: cytd[l] <==> cytd[c] R_ADNtl subsystem: Transport, Lysosomal R_ADNtl equation: adn[l] <==> adn[c]
reactant: 838813
reactant: 838837
product: 838957
reactant: 838873
product: 838921
reactant: 838801
reactant: 838825
reactant: 838861

795874
stoichiometry: 1.0
species: 744447
type: SpeciesReference

739999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Glutamate_C5H8NO4
type: Species

760078
stoichiometry: 1.0
species: 746449
type: SpeciesReference

780410
stoichiometry: 35.0
species: 734127
type: SpeciesReference

793967
stoichiometry: 2.0
species: 741199
type: SpeciesReference

834361
stoichiometry: 23.0
species: 741259
type: SpeciesReference

824663
stoichiometry: 1.0
species: 741681
type: SpeciesReference

789723
stoichiometry: 1.0
species: 736983
type: SpeciesReference

743048
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: ITP_C10H11N4O14P3
type: Species

854496
stoichiometry: 3.0
species: 751082
type: SpeciesReference

733443
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

778819
stoichiometry: 5.0
species: 747698
type: SpeciesReference

788998
stoichiometry: 1.0
species: 735565
type: SpeciesReference

835051
stoichiometry: 1.0
species: 753471
type: SpeciesReference

735252
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cysteamine_C2H8NS
type: Species

854749
stoichiometry: 1.0
species: 741283
type: SpeciesReference

038984
modifier: 833290
product: 833158
notes: R_GCCbim subsystem: Glycine, Serine, and Threonine Metabolism R_GCCbim equation: [m] : alpro + thf --> dhlpro + mlthf + nh4 R_GCCcm subsystem: Glycine, Serine, and Threonine Metabolism R_GCCcm equation: [m] : dhlpro + nad <==> h + lpro + nadh R_GCC2bim subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2bim equation: [m] : alpam + thf --> dhlam + mlthf + nh4 R_GCCam subsystem: Glycine, Serine, and Threonine Metabolism R_GCCam equation: [m] : gly + h + lpro <==> alpro + co2 R_GCC2cm subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2cm equation: [m] : dhlam + nad <==> h + lpam + nadh R_GCC2am subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2am equation: [m] : gly + h + lpam <==> alpam + co2
modifier: 833302
product: 833170
modifier: 833314
modifier: 833194
is: http://identifiers.org/ec-code/2.1.2.10
reversible: false
modifier: 833230
is: ENSCAFG00000011489.2
modifier: 833242
product: 833182
reactant: 833110
product: 833146
modifier: 833254
modifier: 833266
modifier: 833206
reactant: 833134
is: http://identifiers.org/ec-code/1.4.4.2
is: ENSCAFG00000020014.2
reactant: 833122
fast: false
modifier: 833278
modifier: 833218
is: http://identifiers.org/ec-code/1.8.1.4
type: Reaction
is: ENSCAFG00000013180.2

809965
stoichiometry: 4.0
species: 741151
type: SpeciesReference

845099
stoichiometry: 1.0
species: 738015
type: SpeciesReference

765107
stoichiometry: 1.0
species: 744904
type: SpeciesReference

777591
stoichiometry: 1.0
species: 752764
type: SpeciesReference

795766
stoichiometry: 1.0
species: 743685
type: SpeciesReference

750141
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylserine (homo sapiens)_C6H11NO6PFULLRCO2FULLR2CO2
type: Species

806497
stoichiometry: 1.0
species: 732404
type: SpeciesReference

030621
product: 756248
reactant: 756236
notes: R_CHSTEROLt1 subsystem: Transport, Mitochondrial R_CHSTEROLt1 equation: chsterol[l] <==> chsterol[m]
is: ENSCAFG00000016383.2
fast: false
reversible: true
name: cholesterol intracellular transport
type: Reaction

784911
stoichiometry: 1.0
species: 730922
type: SpeciesReference

035143
product: 796260
reactant: 796236
type: Reaction
reversible: false
reactant: 796212
fast: false
product: 796284
product: 796272
is: ENSCAFG00000018994.2
notes: R_DHCR243r subsystem: Cholesterol Metabolism R_DHCR243r equation: [r] : dsmsterol + fadh2 --> chsterol + fad R_DHCR242r subsystem: Cholesterol Metabolism R_DHCR242r equation: [r] : chlstol + fadh2 --> fad + lthstrl R_DHCR241r subsystem: Cholesterol Metabolism R_DHCR241r equation: [r] : fadh2 + zymst --> fad + zymstnl
product: 796296
reactant: 796224
reactant: 796248

747722
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: O2_O2
type: Species

779291
stoichiometry: 1.0
species: 747209
type: SpeciesReference

729307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Cysteate_C3H6NO5S
type: Species

811830
stoichiometry: 1.0
species: 732272
type: SpeciesReference

750986
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenocysteine_C3H7NO2Se
type: Species

824397
stoichiometry: 1.0
species: 742455
type: SpeciesReference

774350
stoichiometry: 1.0
species: 747173
type: SpeciesReference

832845
stoichiometry: 1.0
species: 749466
type: SpeciesReference

733654
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: chitin_C24H41N3O16
type: Species

842639
stoichiometry: 1.0
species: 726560
type: SpeciesReference

777653
stoichiometry: 1.0
species: 730922
type: SpeciesReference

762179
stoichiometry: 1.0
species: 735409
type: SpeciesReference

841377
stoichiometry: 1.0
species: 731682
type: SpeciesReference

732829
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Biotin_C10H15N2O3S
type: Species

761453
stoichiometry: 1.0
species: 752217
type: SpeciesReference

805526
stoichiometry: 10.0
species: 746978
type: SpeciesReference

735360
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Deoxyadenosine_C10H13N5O3
type: Species

736644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N,N-Dimethylglycine_C4H9NO2
type: Species

733594
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Cholesterol_C27H46O
type: Species

850827
stoichiometry: 1.0
species: 741259
type: SpeciesReference

729871
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Tn antigen_C8H14NO5X
type: Species

830337
stoichiometry: 1.0
species: 734513
type: SpeciesReference

809891
stoichiometry: 1.0
species: 753302
type: SpeciesReference

744411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X
type: Species

808361
stoichiometry: 2.0
species: 730184
type: SpeciesReference

811300
stoichiometry: 5.0
species: 731561
type: SpeciesReference

820558
stoichiometry: 1.0
species: 745447
type: SpeciesReference

848173
stoichiometry: 1.0
species: 745290
type: SpeciesReference

729234
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: protein-linked asparagine residue (N-glycosylation site)_XH
type: Species

753290
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: UDPglucose_C15H22N2O17P2
type: Species

821342
stoichiometry: 1.0
species: 737302
type: SpeciesReference

780121
stoichiometry: 1.0
species: 732744
type: SpeciesReference

743878
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 27_C205H328N14O171S8X
type: Species

809278
stoichiometry: 1.0
species: 730657
type: SpeciesReference

741741
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Homogentisate_C8H7O4
type: Species

802832
stoichiometry: 1.0
species: 732404
type: SpeciesReference

771734
stoichiometry: 10.0
species: 746930
type: SpeciesReference

773571
stoichiometry: 1.0
species: 744796
type: SpeciesReference

812637
stoichiometry: 1.0
species: 732404
type: SpeciesReference

849936
stoichiometry: 2.0
species: 748375
type: SpeciesReference

769843
stoichiometry: 1.0
species: 746978
type: SpeciesReference

765536
stoichiometry: 4.0
species: 748651
type: SpeciesReference

848995
stoichiometry: 1.0
species: 734987
type: SpeciesReference

781204
stoichiometry: 1.0
species: 733738
type: SpeciesReference

776043
stoichiometry: 1.0
species: 734345
type: SpeciesReference

740337
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glycerol_C3H8O3
type: Species

738329
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Formate_CH1O2
type: Species

748567
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2
type: Species

774749
stoichiometry: 1.0
species: 753206
type: SpeciesReference

738474
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Fructose_C6H12O6
type: Species

838433
stoichiometry: 2.0
species: 753133
type: SpeciesReference

730500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)1 (Glc)1 (GlcNAc)1 (Cer)1_C38H69N2O17FULLRCO
type: Species

808469
stoichiometry: 1.0
species: 731561
type: SpeciesReference

788613
stoichiometry: 1.0
species: 750044
type: SpeciesReference

746110
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: D-Mannose_C6H12O6
type: Species

768879
stoichiometry: 1.0
species: 749043
type: SpeciesReference

040778
product: 852063
reactant: 852015
is: http://identifiers.org/ec-code/3.1.3.3
reversible: false
reactant: 852003
product: 852051
is: http://identifiers.org/ec-code/3.1.4.17
is: ENSCAFG00000007100.2
notes: R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PSP_L subsystem: Glycine, Serine, and Threonine Metabolism R_PSP_L equation: [c] : h2o + pser-L --> pi + ser-L
reactant: 852027
is: ENSCAFG00000018583.2
is: ENSCAFG00000023181.1
product: 852075
type: Reaction
is: ENSCAFG00000018594.1
product: 852039
fast: false

810820
stoichiometry: 1.0
species: 726704
type: SpeciesReference

771673
stoichiometry: 2.0
species: 741151
type: SpeciesReference

797934
stoichiometry: 1.0
species: 741681
type: SpeciesReference

737399
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})_C48H81O41X
type: Species

829710
stoichiometry: 1.0
species: 739865
type: SpeciesReference

783159
stoichiometry: 1.0
species: 753266
type: SpeciesReference

751239
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Sulfate_O4S
type: Species

735469
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: dAMP_C10H12N5O6P
type: Species

746810
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: n2m2nmasn (w/o peptide linkage)_C58H97N5O41
type: Species

744399
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X
type: Species

033197
reactant: 779109
is: ENSCAFG00000009931.2
product: 779121
fast: false
name: K+-Cl- cotransport
notes: R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]
reactant: 779097
type: Reaction
reversible: true
product: 779134

732574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Betaine aldehyde_C5H12NO
type: Species

731248
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8
type: Species

817607
stoichiometry: 1.0
species: 746413
type: SpeciesReference

728704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _5-Hydroxyindoleacetate_C10H8NO3
type: Species

795322
stoichiometry: 1.0
species: 734005
type: SpeciesReference

741560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S
type: Species

765011
stoichiometry: 1.0
species: 731465
type: SpeciesReference

739510
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: glycocholate_C26H43NO6
type: Species

767786
stoichiometry: 1.0
species: 747987
type: SpeciesReference

754512
stoichiometry: 1.0
species: 740313
type: SpeciesReference

766256
stoichiometry: 1.0
species: 748097
type: SpeciesReference

031451
reversible: false
is: http://identifiers.org/ec-code/3.1.1.3
reactant: 763584
product: 763609
fast: false
product: 763597
product: 763621
product: 763646
is: ENSCAFG00000010161.2
reactant: 763572
type: Reaction
product: 763634
notes: R_LPS2 subsystem: Triacylglycerol Synthesis R_LPS2 equation: [c] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS subsystem: Triacylglycerol Synthesis R_LPS equation: [c] : h2o + tag_hs --> Rtotal3 + dag_hs + h
reactant: 763560

855545
stoichiometry: 1.0
species: 733021
type: SpeciesReference

030813
product: 758001
notes: R_SUCOASm subsystem: Citric Acid Cycle R_SUCOASm equation: [m] : atp + coa + succ <==> adp + pi + succoa R_SUCOAS1m subsystem: Citric Acid Cycle R_SUCOAS1m equation: [m] : coa + gtp + succ <==> gdp + pi + succoa R_MECOAS1m subsystem: C5-Branched dibasic acid metabolism R_MECOAS1m equation: [m] : coa + gtp + mescon <==> gdp + mescoa + pi R_MECOALm subsystem: C5-Branched dibasic acid metabolism R_MECOALm equation: [m] : atp + coa + mescon <==> adp + mescoa + pi R_ITCOALm subsystem: C5-Branched dibasic acid metabolism R_ITCOALm equation: [m] : atp + coa + itacon <==> adp + itaccoa + pi R_ITCOAL1m subsystem: C5-Branched dibasic acid metabolism R_ITCOAL1m equation: [m] : coa + gtp + itacon <==> gdp + itaccoa + pi
reactant: 757953
product: 757965
is: http://identifiers.org/ec-code/6.2.1.5
product: 758013
is: http://identifiers.org/ec-code/6.2.1.4
reactant: 757904
product: 757989
reversible: true
is: ENSCAFG00000007987.2
reactant: 757916
reactant: 757941
reactant: 757892
fast: false
reactant: 757929
type: Reaction
product: 757977
product: 758025

805799
stoichiometry: 10.0
species: 747050
type: SpeciesReference

763852
stoichiometry: 1.0
species: 744546
type: SpeciesReference

832689
stoichiometry: 2.0
species: 741151
type: SpeciesReference

831366
stoichiometry: 1.0
species: 746001
type: SpeciesReference

733516
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Choline phosphate_C5H13NO4P
type: Species

803520
stoichiometry: 1.0
species: 751977
type: SpeciesReference

822574
stoichiometry: 1.0
species: 748591
type: SpeciesReference

804272
stoichiometry: 1.0
species: 752854
type: SpeciesReference

731188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adenylylselenate_C10H12N5O10PSe
type: Species

786376
stoichiometry: 3.0
species: 741332
type: SpeciesReference

772195
stoichiometry: 1.0
species: 744447
type: SpeciesReference

821197
stoichiometry: 1.0
species: 746629
type: SpeciesReference

745892
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Malonyl-[acyl-carrier protein]_C14H22N2O10PRS
type: Species

032114
product: 769734
type: Reaction
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T24g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T24g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5b + h + pap R_S6T20g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T20g equation: [g] : cs_c_pre3 + paps --> cspg_c + h + pap R_S6T19g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T19g equation: [g] : cs_pre + (2) paps --> cs_c,d,e_pre1 + (2) h + (2) pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap R_S6T21g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T21g equation: [g] : cs_d_pre4 + paps --> cs_d_pre5 + h + pap
product: 769758
reactant: 769686
product: 769770
product: 769806
reactant: 769710
product: 769794
reactant: 769698
product: 769830
is: http://identifiers.org/ec-code/2.8.2.17
product: 769746
reversible: false
is: ENSCAFG00000014410.2
reactant: 769722
reactant: 769674
fast: false
reactant: 769638
reactant: 769662
product: 769782
product: 769818
reactant: 769650

033390
product: 781012
name: mevalonate kinase (atp)
product: 781024
reactant: 780988
is: http://identifiers.org/ec-code/2.7.1.36
type: Reaction
fast: false
reactant: 781000
is: ENSCAFG00000010834.2
product: 781036
notes: R_MEVK1x subsystem: Cholesterol Metabolism R_MEVK1x equation: [x] : atp + mev-R --> 5pmev + adp + h
reversible: false

800532
stoichiometry: 1.0
species: 731405
type: SpeciesReference

805225
stoichiometry: 1.0
species: 750153
type: SpeciesReference

840544
stoichiometry: 1.0
species: 748097
type: SpeciesReference

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stoichiometry: 1.0
species: 733286
type: SpeciesReference

838157
stoichiometry: 1.0
species: 733033
type: SpeciesReference

800231
stoichiometry: 1.0
species: 746677
type: SpeciesReference

791473
stoichiometry: 1.0
species: 731127
type: SpeciesReference

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stoichiometry: 1.0
species: 731694
type: SpeciesReference

768198
stoichiometry: 1.0
species: 736388
type: SpeciesReference

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stoichiometry: 1.0
species: 741151
type: SpeciesReference

770353
stoichiometry: 1.0
species: 739815
type: SpeciesReference

781613
stoichiometry: 1.0
species: 736777
type: SpeciesReference

758654
stoichiometry: 1.0
species: 750671
type: SpeciesReference

732635
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Bilirubin beta-diglucuronide_C45H50N4O18
type: Species

852376
stoichiometry: 1.0
species: 747601
type: SpeciesReference

747601
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: nervonic acid_C24H45O2
type: Species

799967
stoichiometry: 1.0
species: 741151
type: SpeciesReference

822004
stoichiometry: 1.0
species: 749984
type: SpeciesReference

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stoichiometry: 2.0
species: 749394
type: SpeciesReference

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stoichiometry: 1.0
species: 741416
type: SpeciesReference

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stoichiometry: 111.0
species: 734091
type: SpeciesReference

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stoichiometry: 1.0
species: 737386
type: SpeciesReference

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stoichiometry: 2.0
species: 741151
type: SpeciesReference

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stoichiometry: 1.0
species: 731610
type: SpeciesReference

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stoichiometry: 1.0
species: 740825
type: SpeciesReference

802977
stoichiometry: 1.0
species: 749188
type: SpeciesReference

763512
stoichiometry: 1.0
species: 741308
type: SpeciesReference

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stoichiometry: 7.0
species: 741078
type: SpeciesReference

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stoichiometry: 1.0
species: 741308
type: SpeciesReference

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stoichiometry: 1.0
species: 729762
type: SpeciesReference

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stoichiometry: 1.0
species: 744157
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GT1a (homo sapiens)_C77H127N5O46FULLRCO
type: Species

755032
stoichiometry: 1.0
species: 742176
type: SpeciesReference

805587
stoichiometry: 2.0
species: 747099
type: SpeciesReference

844615
stoichiometry: 1.0
species: 730209
type: SpeciesReference

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stoichiometry: 1.0
species: 748483
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Glutamine_C5H10N2O3
type: Species

818907
stoichiometry: 1.0
species: 737290
type: SpeciesReference

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stoichiometry: 2.0
species: 749454
type: SpeciesReference

854917
stoichiometry: 1.0
species: 740812
type: SpeciesReference

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stoichiometry: 1.0
species: 741151
type: SpeciesReference

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stoichiometry: 5.0
species: 746918
type: SpeciesReference

729762
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: R total carnitine_CO2FULLRC7H14NO2
type: Species

762968
stoichiometry: 1.0
species: 753750
type: SpeciesReference

803748
stoichiometry: 1.0
species: 746689
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: L-Glutamate_C5H8NO4
type: Species

836315
stoichiometry: 1.0
species: 744650
type: SpeciesReference

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stoichiometry: 1.0
species: 726876
type: SpeciesReference

802554
stoichiometry: 1.0
species: 745013
type: SpeciesReference

776454
stoichiometry: 1.0
species: 733335
type: SpeciesReference

822297
stoichiometry: 1.0
species: 736474
type: SpeciesReference

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stoichiometry: 1.0
species: 735409
type: SpeciesReference

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stoichiometry: 16.0
species: 741163
type: SpeciesReference

810159
stoichiometry: 1.0
species: 751651
type: SpeciesReference

750830
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: sialyl-T antigen_C25H40N2O18X
type: Species

826073
stoichiometry: 1.0
species: 751796
type: SpeciesReference

839823
stoichiometry: 1.0
species: 745651
type: SpeciesReference

812914
stoichiometry: 1.0
species: 746629
type: SpeciesReference

739852
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Glucose_C6H12O6
type: Species

756557
stoichiometry: 1.0
species: 739522
type: SpeciesReference

794247
stoichiometry: 1.0
species: 734999
type: SpeciesReference

795622
stoichiometry: 1.0
species: 732889
type: SpeciesReference

837291
stoichiometry: 1.0
species: 728450
type: SpeciesReference

853638
stoichiometry: 1.0
species: 734054
type: SpeciesReference

848897
stoichiometry: 1.0
species: 744133
type: SpeciesReference

778312
stoichiometry: 1.0
species: 740530
type: SpeciesReference

030501
product: 755333
reactant: 755297
is: ENSCAFG00000003884.2
fast: false
type: Reaction
notes: R_TRDRm subsystem: Nucleotides R_TRDRm equation: [m] : h + nadph + trdox --> nadp + trdrd
reactant: 755309
is: ENSCAFG00000014373.2
reversible: false
reactant: 755321
product: 755345
is: http://identifiers.org/ec-code/1.8.1.9
name: thioredoxin reductase (NADPH)

747197
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3
type: Species

823974
stoichiometry: 1.0
species: 744241
type: SpeciesReference

770815
stoichiometry: 1.0
species: 731573
type: SpeciesReference

789843
stoichiometry: 1.0
species: 749261
type: SpeciesReference

853880
stoichiometry: 1.0
species: 751324
type: SpeciesReference

033900
notes: R_PNTK subsystem: CoA Biosynthesis R_PNTK equation: [c] : atp + pnto-R --> 4ppan + adp + h
product: 784923
reversible: false
product: 784911
is: ENSCAFG00000017049.2
product: 784935
is: ENSCAFG00000019416.2
is: http://identifiers.org/ec-code/2.7.1.33
type: Reaction
fast: false
is: ENSCAFG00000007165.2
reactant: 784887
name: pantothenate kinase
reactant: 784899

771445
stoichiometry: 1.0
species: 730645
type: SpeciesReference

746545
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 3,4-bisphosphate_C6H10O12P2
type: Species

845788
stoichiometry: 1.0
species: 726331
type: SpeciesReference

796236
stoichiometry: 3.0
species: 738099
type: SpeciesReference

040561
reactant: 849598
type: Reaction
reactant: 849610
is: http://identifiers.org/ec-code/2.4.2.2
reversible: true
product: 849646
notes: R_DURIPP subsystem: Nucleotides R_DURIPP equation: [c] : duri + pi <==> 2dr1p + ura R_PYNP2r subsystem: Pyrimidine Catabolism R_PYNP2r equation: [c] : pi + uri <==> r1p + ura
is: ENSCAFG00000014262.2
fast: false
product: 849634
reactant: 849586
product: 849622

777409
stoichiometry: 5.0
species: 741271
type: SpeciesReference

793918
stoichiometry: 1.0
species: 726766
type: SpeciesReference

833482
stoichiometry: 2.0
species: 741259
type: SpeciesReference

827113
stoichiometry: 1.0
species: 741283
type: SpeciesReference

789445
stoichiometry: 1.0
species: 731465
type: SpeciesReference

034769
reactant: 792956
name: citrate transport via sodium symport
is: ENSCAFG00000015368.2
reactant: 792944
product: 792981
type: Reaction
product: 792968
notes: R_CITt4_4 subsystem: Transport, Extracellular R_CITt4_4 equation: cit[e] + (4) na1[e] <==> cit[c] + (4) na1[c]
reversible: true
fast: false

780494
stoichiometry: 1.0
species: 751989
type: SpeciesReference

819136
stoichiometry: 1.0
species: 733033
type: SpeciesReference

757272
stoichiometry: 32.0
species: 747087
type: SpeciesReference

816476
stoichiometry: 1.0
species: 736036
type: SpeciesReference

816608
stoichiometry: 1.0
species: 736644
type: SpeciesReference

795286
stoichiometry: 1.0
species: 734091
type: SpeciesReference

835039
stoichiometry: 1.0
species: 753399
type: SpeciesReference

766110
stoichiometry: 1.0
species: 749309
type: SpeciesReference

834859
stoichiometry: 6.0
species: 747099
type: SpeciesReference

788469
stoichiometry: 1.0
species: 736995
type: SpeciesReference

825880
stoichiometry: 1.0
species: 739815
type: SpeciesReference

821052
stoichiometry: 1.0
species: 728764
type: SpeciesReference

845343
stoichiometry: 1.0
species: 750695
type: SpeciesReference

811950
stoichiometry: 1.0
species: 728535
type: SpeciesReference

851557
stoichiometry: 1.0
species: 741259
type: SpeciesReference

795838
stoichiometry: 1.0
species: 744314
type: SpeciesReference

796806
stoichiometry: 1.0
species: 749442
type: SpeciesReference

030717
product: 756872
type: Reaction
is: ENSCAFG00000010579.2
reactant: 756751
product: 756945
is: http://identifiers.org/ec-code/2.4.1.175
reactant: 756738
reactant: 756824
notes: R_GLCAT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT5g equation: [g] : cs_e_pre2 + udpglcur --> cs_e_pre3 + h + udp R_GLCAT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT4g equation: [g] : cs_d_pre2 + udpglcur --> cs_d_pre3 + h + udp R_GLCAT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT3g equation: [g] : cs_c,d,e_pre1 + udpglcur --> cs_c_pre2 + h + udp R_GLCAT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT2g equation: [g] : cs_a,b,e_pre1 + udpglcur --> cs_a,b_pre2 + h + udp R_GALNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT5g equation: [g] : cs_e_pre3 + uacgam --> cs_e_pre4 + h + udp R_GALNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT4g equation: [g] : cs_d_pre3 + uacgam --> cs_d_pre4 + h + udp R_GALNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT3g equation: [g] : cs_c_pre2 + uacgam --> cs_c_pre3 + h + udp R_GALNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT2g equation: [g] : cs_a,b_pre2 + uacgam --> cs_a,b_pre3 + h + udp
fast: false
product: 756884
reversible: false
product: 756920
product: 756860
reactant: 756787
product: 756848
reactant: 756726
reactant: 756812
product: 756836
product: 756896
reactant: 756799
reactant: 756763
is: ENSCAFG00000015609.2
product: 756908
reactant: 756713
product: 756932
reactant: 756775
is: ENSCAFG00000000726.2

768451
stoichiometry: 1.0
species: 734091
type: SpeciesReference

843516
stoichiometry: 2.0
species: 742600
type: SpeciesReference

822719
stoichiometry: 1.0
species: 732441
type: SpeciesReference

819642
stoichiometry: 1.0
species: 743600
type: SpeciesReference

760199
stoichiometry: 1.0
species: 746978
type: SpeciesReference

750261
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Putrescine_C4H14N2
type: Species

836906
stoichiometry: 1.0
species: 735829
type: SpeciesReference

779061
stoichiometry: 2.0
species: 741223
type: SpeciesReference

839931
stoichiometry: 1.0
species: 747209
type: SpeciesReference

779134
stoichiometry: 1.0
species: 733738
type: SpeciesReference

828820
stoichiometry: 1.0
species: 739317
type: SpeciesReference

855026
stoichiometry: 1.0
species: 730609
type: SpeciesReference

756848
stoichiometry: 8.0
species: 753157
type: SpeciesReference

809840
stoichiometry: 1.0
species: 729441
type: SpeciesReference

805430
stoichiometry: 1.0
species: 733654
type: SpeciesReference

748711
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2
type: Species

822141
stoichiometry: 2.0
species: 733933
type: SpeciesReference

038755
notes: R_MALT subsystem: Starch and Sucrose Metabolism R_MALT equation: [c] : h2o + malt --> (2) glc-D R_MLTG1 subsystem: Starch and Sucrose Metabolism R_MLTG1 equation: [c] : h2o + malttr --> glc-D + malt
fast: false
reactant: 831366
is: http://identifiers.org/ec-code/3.2.1.20
product: 831402
is: ENSCAFG00000010104.2
product: 831390
reactant: 831378
reactant: 831354
reversible: false
type: Reaction

765765
stoichiometry: 1.0
species: 741548
type: SpeciesReference

797349
stoichiometry: 1.0
species: 743902
type: SpeciesReference

808049
stoichiometry: 1.0
species: 733750
type: SpeciesReference

849248
stoichiometry: 2.0
species: 743420
type: SpeciesReference

038100
product: 826567
notes: R_METS subsystem: Methionine Metabolism R_METS equation: [c] : 5mthf + hcys-L --> h + met-L + thf
reactant: 826518
is: ENSCAFG00000010464.2
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/2.1.1.13
product: 826554
product: 826542
reactant: 826530
fast: false
name: methionine synthase

853747
stoichiometry: 1.0
species: 741102
type: SpeciesReference

828496
stoichiometry: 1.0
species: 747698
type: SpeciesReference

735023
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 4_C45H65N2O48S4X
type: Species

034685
fast: false
product: 792402
type: Reaction
reactant: 792366
reactant: 792378
reversible: false
is: http://identifiers.org/ec-code/1.5.1.2
reactant: 792354
is: ENSCAFG00000016140.2
reactant: 792390
notes: R_P5CR subsystem: Urea cycle/amino group metabolism R_P5CR equation: [c] : 1pyr5c + (2) h + nadph --> nadp + pro-L R_P5CRx subsystem: Urea cycle/amino group metabolism R_P5CRx equation: [c] : 1pyr5c + (2) h + nadh --> nad + pro-L
product: 792426
is: ENSCAFG00000001325.2
product: 792414

816318
stoichiometry: 1.0
species: 749200
type: SpeciesReference

817511
stoichiometry: 1.0
species: 734163
type: SpeciesReference

032835
reactant: 776648
fast: false
is: http://identifiers.org/ec-code/2.6.1.7
product: 776685
notes: R_3HKYNAKGAT subsystem: Tryptophan metabolism R_3HKYNAKGAT equation: [c] : akg + hLkynr --> 42A3HP24DB + glu-L R_KYNAKGAT subsystem: Tryptophan metabolism R_KYNAKGAT equation: [c] : Lkynr + akg --> 4aphdob + glu-L
reactant: 776636
is: ENSCAFG00000020030.2
type: Reaction
reversible: false
reactant: 776624
product: 776673
product: 776661

733933
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: CMP-N-acetylneuraminate_C20H29N4O16P
type: Species

841209
stoichiometry: 1.0
species: 747050
type: SpeciesReference

735180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: CTP_C9H12N3O14P3
type: Species

745278
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: gamma-linolenoyl-CoA_C39H60N7O17P3S
type: Species

811530
stoichiometry: 5.0
species: 752496
type: SpeciesReference

844107
stoichiometry: 1.0
species: 744314
type: SpeciesReference

838777
stoichiometry: 1.0
species: 749358
type: SpeciesReference

731477
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: beta-Alanine_C3H7NO2
type: Species

813796
stoichiometry: 1.0
species: 750044
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: stearidonyl coenzyme A_C39H58N7O17P3S
type: Species

830753
stoichiometry: 1.0
species: 748350
type: SpeciesReference

798595
stoichiometry: 9.0
species: 730946
type: SpeciesReference

770281
stoichiometry: 1.0
species: 739827
type: SpeciesReference

796128
stoichiometry: 1.0
species: 744265
type: SpeciesReference

768561
stoichiometry: 1.0
species: 748675
type: SpeciesReference

766919
stoichiometry: 2.0
species: 747686
type: SpeciesReference

811252
stoichiometry: 1.0
species: 739027
type: SpeciesReference

727771
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Phospho-D-glycerate_C3H4O7P
type: Species

837050
stoichiometry: 1.0
species: 751917
type: SpeciesReference

748290
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Oxalate_C2O4
type: Species

762808
stoichiometry: 1.0
species: 753762
type: SpeciesReference

728631
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _5-Formyltetrahydrofolate_C20H21N7O7
type: Species

835147
stoichiometry: 1.0
species: 730500
type: SpeciesReference

845499
stoichiometry: 1.0
species: 741259
type: SpeciesReference

753495
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Uracil_C4H4N2O2
type: Species

781860
stoichiometry: 1.0
species: 739729
type: SpeciesReference

844471
stoichiometry: 1.0
species: 740481
type: SpeciesReference

836423
stoichiometry: 1.0
species: 741259
type: SpeciesReference

806172
stoichiometry: 1.0
species: 744676
type: SpeciesReference

747038
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

819244
stoichiometry: 7.0
species: 741151
type: SpeciesReference

727360
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Hydroxyanthranilate_C7H7NO3
type: Species

819799
stoichiometry: 1.0
species: 744374
type: SpeciesReference

840786
stoichiometry: 1.0
species: 732200
type: SpeciesReference

797072
stoichiometry: 2.0
species: 733884
type: SpeciesReference

031717
product: 765560
product: 765536
reactant: 765500
reactant: 765476
product: 765596
product: 765548
reversible: false
fast: false
is: ENSCAFG00000002873.2
is: ENSCAFG00000002871.2
product: 765572
reactant: 765512
notes: R_DOPASULT subsystem: Tyrosine metabolism R_DOPASULT equation: [c] : dopa + paps --> dopasf + h + pap R_4NPHSULT subsystem: CYP Metabolism R_4NPHSULT equation: [c] : 4nph + paps --> 4nphsf + h + pap R_TYMSULT subsystem: Tyrosine metabolism R_TYMSULT equation: [c] : paps + tym --> h + pap + tymsf R_NRPPHRSULT subsystem: Tyrosine metabolism R_NRPPHRSULT equation: [c] : nrpphr + paps --> h + nrpphrsf + pap
type: Reaction
reactant: 765488
reactant: 765524
is: http://identifiers.org/ec-code/2.8.2.1
product: 765584

833374
stoichiometry: 1.0
species: 747405
type: SpeciesReference

843407
stoichiometry: 1.0
species: 740663
type: SpeciesReference

789555
stoichiometry: 1.0
species: 733859
type: SpeciesReference

763621
stoichiometry: 1.0
species: 729662
type: SpeciesReference

036700
fast: false
is: http://identifiers.org/ec-code/3.6.3.14
reactant: 810964
is: ENSCAFG00000004941.2
product: 811036
product: 811072
reactant: 811024
is: http://identifiers.org/ec-code/1.11.1.6
reactant: 810988
product: 811060
reactant: 811012
notes: R_CAT2p subsystem: Glycolysis/Gluconeogenesis R_CAT2p equation: [x] : etoh + h2o2 --> acald + (2) h2o R_ATPS4m subsystem: Oxidative Phosphorylation R_ATPS4m equation: adp[m] + (4) h[c] + pi[m] --> atp[m] + (3) h[m] + h2o[m] R_CATm subsystem: ROS Detoxification R_CATm equation: [m] : (2) h2o2 --> (2) h2o + o2 R_CATp subsystem: Miscellaneous R_CATp equation: [x] : (2) h2o2 --> (2) h2o + o2
type: Reaction
is: ENSCAFG00000024922.1
reversible: false
reactant: 810976
product: 811096
product: 811108
product: 811048
reactant: 811000
product: 811084

035493
fast: false
is: http://identifiers.org/ec-code/3.6.1.28
is: ENSCAFG00000011651.1
product: 800834
notes: R_THMTP subsystem: Thiamine Metabolism R_THMTP equation: [c] : h2o + thmtp --> h + pi + thmpp
reactant: 800822
reactant: 800810
product: 800858
type: Reaction
reversible: false
product: 800846
name: thiamine-triphosphatase

760623
stoichiometry: 3.0
species: 748687
type: SpeciesReference

777519
stoichiometry: 1.0
species: 744598
type: SpeciesReference

746653
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S
type: Species

802361
stoichiometry: 1.0
species: 750128
type: SpeciesReference

807110
stoichiometry: 2.0
species: 741283
type: SpeciesReference

040453
is: http://identifiers.org/ec-code/2.7.7.23
fast: false
name: UDP-N-acetylglucosamine diphosphorylase
type: Reaction
reactant: 847245
reactant: 847257
is: ENSCAFG00000013117.2
reversible: false
reactant: 847233
is: ENSCAFG00000019510.2
product: 847281
notes: R_UAGDP subsystem: Aminosugar Metabolism R_UAGDP equation: [c] : acgam1p + h + utp --> ppi + uacgam
is: ENSCAFG00000019519.2
product: 847269

806809
stoichiometry: 1.0
species: 747099
type: SpeciesReference

770925
stoichiometry: 1.0
species: 740193
type: SpeciesReference

852268
stoichiometry: 1.0
species: 747367
type: SpeciesReference

759208
stoichiometry: 3.0
species: 734091
type: SpeciesReference

774858
stoichiometry: 1.0
species: 739987
type: SpeciesReference

749454
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Propanoyl-CoA_C24H36N7O17P3S
type: Species

805640
stoichiometry: 1.0
species: 744676
type: SpeciesReference

781553
stoichiometry: 1.0
species: 753399
type: SpeciesReference

038184
product: 827028
reactant: 827003
name: NAD kinase
notes: R_NADK subsystem: NAD Metabolism R_NADK equation: [c] : atp + nad --> adp + h + nadp
product: 827052
reversible: false
reactant: 827015
is: ENSCAFG00000019219.2
product: 827040
fast: false
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.23

738991
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1905H3140N20O770P20
type: Species

742916
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Inosine_C10H12N4O5
type: Species

829446
stoichiometry: 2.0
species: 743072
type: SpeciesReference

825519
stoichiometry: 1.0
species: 735216
type: SpeciesReference

801915
stoichiometry: 1.0
species: 746641
type: SpeciesReference

748860
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2
type: Species

756445
stoichiometry: 1.0
species: 731864
type: SpeciesReference

776152
stoichiometry: 8.0
species: 741187
type: SpeciesReference

790919
stoichiometry: 1.0
species: 731042
type: SpeciesReference

032222
reactant: 771034
type: Reaction
notes: R_ST8SIA12 subsystem: Sphingolipid Metabolism R_ST8SIA12 equation: [g] : cmpacna + gm3_hs --> cmp + gd3_hs + h R_ST8SIA11 subsystem: Sphingolipid Metabolism R_ST8SIA11 equation: [g] : acngalgbside_hs + cmpacna --> acnacngalgbside_hs + cmp + h
reversible: false
product: 771082
reactant: 771046
product: 771094
product: 771106
is: ENSCAFG00000011838.2
product: 771070
fast: false
reactant: 771058
is: http://identifiers.org/ec-code/2.4.99.8

741850
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

743348
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 27_C104H169N7O88S4
type: Species

810712
stoichiometry: 1.0
species: 736523
type: SpeciesReference

850045
stoichiometry: 1.0
species: 727130
type: SpeciesReference

732853
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Biotin_C10H15N2O3S
type: Species

728932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

807074
stoichiometry: 1.0
species: 747294
type: SpeciesReference

729343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Cystine_C6H12N2O4S2
type: Species

030609
product: 756176
reactant: 756104
type: Reaction
is: http://identifiers.org/ec-code/3.6.1.6
reversible: false
is: http://identifiers.org/ec-code/3.6.1.15
product: 756164
product: 756224
product: 756152
reactant: 756140
product: 756212
notes: R_NTP3e subsystem: Nucleotides R_NTP3e equation: [e] : gtp + h2o --> gdp + h + pi R_NDP7ex subsystem: Nucleotides R_NDP7ex equation: [e] : h2o + udp --> h + pi + ump R_NDP10ex subsystem: Nucleotides R_NDP10ex equation: [e] : h2o + idp --> h + imp + pi R_NDP3ex subsystem: Nucleotides R_NDP3ex equation: [e] : gdp + h2o --> gmp + h + pi R_NDP8ex subsystem: Nucleotides R_NDP8ex equation: [e] : h2o + utp --> h + pi + udp
reactant: 756092
reactant: 756080
product: 756200
is: ENSCAFG00000005540.2
reactant: 756116
product: 756188
reactant: 756128
fast: false

761865
stoichiometry: 16.0
species: 747099
type: SpeciesReference

743987
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 35_C241H384N17O205S11X
type: Species

809120
stoichiometry: 1.0
species: 742357
type: SpeciesReference

735312
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Cytidine_C9H13N3O5
type: Species

801612
stoichiometry: 2.0
species: 741259
type: SpeciesReference

743660
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 10_C129H209N9O98S2X
type: Species

736692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

838589
stoichiometry: 1.0
species: 750405
type: SpeciesReference

780278
stoichiometry: 1.0
species: 729525
type: SpeciesReference

783268
stoichiometry: 1.0
species: 744688
type: SpeciesReference

751348
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

794768
stoichiometry: 1.0
species: 738329
type: SpeciesReference

736995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Dopamine_C8H12NO2
type: Species

798174
stoichiometry: 1.0
species: 741536
type: SpeciesReference

740229
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glyceraldehyde_C3H6O3
type: Species

030921
is: http://identifiers.org/ec-code/2.1.3.3
name: ornithine carbamoyltransferase, irreversible
is: ENSCAFG00000014023.2
product: 758739
reactant: 758714
type: Reaction
product: 758751
reactant: 758727
fast: false
notes: R_OCBTm subsystem: Urea cycle/amino group metabolism R_OCBTm equation: [m] : cbp + orn --> citr-L + h + pi
product: 758763
reversible: false

762699
stoichiometry: 1.0
species: 739939
type: SpeciesReference

757929
stoichiometry: 3.0
species: 740994
type: SpeciesReference

766546
stoichiometry: 1.0
species: 751796
type: SpeciesReference

828074
stoichiometry: 1.0
species: 732248
type: SpeciesReference

765167
stoichiometry: 1.0
species: 747830
type: SpeciesReference

828351
stoichiometry: 3.0
species: 732441
type: SpeciesReference

817717
stoichiometry: 1.0
species: 747123
type: SpeciesReference

851401
stoichiometry: 2.0
species: 741259
type: SpeciesReference

040669
reactant: 850887
reactant: 850875
product: 850948
is: ENSCAFG00000023216.1
notes: R_M4BTAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BTAer equation: [r] : mem2emgacpail_hs + pre_prot --> gpi_sig + mem2emgacpail_prot_hs R_H8TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8TAer equation: [r] : gpi_hs + pre_prot --> gpi_prot_hs + gpi_sig R_M4ATAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4ATAer equation: [r] : m(em)3gacpail_hs + pre_prot --> gpi_sig + m(em)3gacpail_prot_hs R_H7_APOS_TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_TAer equation: [r] : em2emgacpail_hs + pre_prot --> em2emgacpail_prot_hs + gpi_sig
product: 850935
fast: false
reactant: 850899
product: 850960
is: ENSCAFG00000007571.2
is: ENSCAFG00000001523.2
reactant: 850911
type: Reaction
product: 850984
reversible: false
product: 850972
reactant: 850923
is: ENSCAFG00000018715.2
is: ENSCAFG00000020384.2

800123
stoichiometry: 1.0
species: 737919
type: SpeciesReference

773993
stoichiometry: 1.0
species: 746701
type: SpeciesReference

801500
stoichiometry: 2.0
species: 742588
type: SpeciesReference

767063
stoichiometry: 1.0
species: 741199
type: SpeciesReference

813579
stoichiometry: 1.0
species: 730367
type: SpeciesReference

733407
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Cholate_C24H39O5
type: Species

848787
stoichiometry: 1.0
species: 743444
type: SpeciesReference

809737
stoichiometry: 1.0
species: 752642
type: SpeciesReference

846864
stoichiometry: 1.0
species: 742296
type: SpeciesReference

731030
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ADPribose_C15H21N5O14P2
type: Species

784238
stoichiometry: 20.0
species: 741259
type: SpeciesReference

792993
stoichiometry: 3.0
species: 748687
type: SpeciesReference

730729
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: sialyl galactosylgloboside (homo sapiens)_C61H105N3O35FULLRCO
type: Species

039827
reactant: 841401
reactant: 841389
is: http://identifiers.org/ec-code/1.14.15.6
product: 841461
notes: R_P45011A1m subsystem: Steroid Metabolism R_P45011A1m equation: [m] : chsterol + h + nadph + (2) o2 --> 4mptnl + (2) h2o + nadp + prgnlone
product: 841473
reactant: 841413
is: ENSCAFG00000015381.2
reversible: false
type: Reaction
fast: false
reactant: 841425
name: Cytochrome P450 11A1, mitochondrial [Precursor]
product: 841449
product: 841437

798728
stoichiometry: 6.0
species: 737266
type: SpeciesReference

851966
stoichiometry: 1.0
species: 739510
type: SpeciesReference

838663
stoichiometry: 1.0
species: 732260
type: SpeciesReference

775775
stoichiometry: 5.0
species: 741416
type: SpeciesReference

741271
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: H+_H
type: Species

774520
stoichiometry: 4.0
species: 732441
type: SpeciesReference

786268
stoichiometry: 1.0
species: 752470
type: SpeciesReference

744036
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 5_C101H164N7O75SX
type: Species

033040
reactant: 778227
reactant: 778203
type: Reaction
notes: R_P4502D6 subsystem: CYP Metabolism R_P4502D6 equation: [c] : debrisoquine + h + nadph + o2 --> 4hdebrisoquine + h2o + nadp
is: ENSCAFG00000000980.2
product: 778239
reactant: 778215
product: 778264
product: 778252
name: cytochrome P450 2D6
reversible: false
fast: false
reactant: 778191

773367
stoichiometry: 1.0
species: 737302
type: SpeciesReference

820667
stoichiometry: 2.0
species: 741199
type: SpeciesReference

854809
stoichiometry: 1.0
species: 734296
type: SpeciesReference

847157
stoichiometry: 1.0
species: 729822
type: SpeciesReference

844507
stoichiometry: 1.0
species: 740699
type: SpeciesReference

749346
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Palmitoylcarnitine_C23H45NO4
type: Species

838373
stoichiometry: 1.0
species: 727905
type: SpeciesReference

774966
stoichiometry: 1.0
species: 726162
type: SpeciesReference

765428
stoichiometry: 1.0
species: 730922
type: SpeciesReference

838000
stoichiometry: 1.0
species: 741271
type: SpeciesReference

795430
stoichiometry: 1.0
species: 747173
type: SpeciesReference

763743
stoichiometry: 3.0
species: 739827
type: SpeciesReference

755309
stoichiometry: 1.0
species: 741308
type: SpeciesReference

767630
stoichiometry: 1.0
species: 741308
type: SpeciesReference

792847
stoichiometry: 1.0
species: 737666
type: SpeciesReference

824168
stoichiometry: 1.0
species: 730922
type: SpeciesReference

734381
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: L-Carnitine_C7H15NO3
type: Species

803411
stoichiometry: 1.0
species: 752013
type: SpeciesReference

812854
stoichiometry: 1.0
species: 727660
type: SpeciesReference

826184
stoichiometry: 2.0
species: 741332
type: SpeciesReference

798426
stoichiometry: 1.0
species: 753725
type: SpeciesReference

736837
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10
type: Species

812288
stoichiometry: 1.0
species: 730524
type: SpeciesReference

741115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Hydrogen peroxide_H2O2
type: Species

802145
stoichiometry: 1.0
species: 741259
type: SpeciesReference

835833
stoichiometry: 1.0
species: 744024
type: SpeciesReference

853314
stoichiometry: 1.0
species: 741308
type: SpeciesReference

771226
stoichiometry: 1.0
species: 728329
type: SpeciesReference

844325
stoichiometry: 1.0
species: 744676
type: SpeciesReference

811312
stoichiometry: 5.0
species: 735228
type: SpeciesReference

763402
stoichiometry: 2.0
species: 741259
type: SpeciesReference

791991
stoichiometry: 3.0
species: 731285
type: SpeciesReference

751783
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Tagatose_C6H12O6
type: Species

837808
stoichiometry: 2.0
species: 741259
type: SpeciesReference

818007
stoichiometry: 1.0
species: 739790
type: SpeciesReference

841365
stoichiometry: 1.0
species: 733981
type: SpeciesReference

827462
stoichiometry: 3.0
species: 735433
type: SpeciesReference

040019
reactant: 842374
type: Reaction
product: 842446
is: http://identifiers.org/ec-code/1.1.1.105
is: ENSCAFG00000007060.2
product: 842434
is: ENSCAFG00000016442.2
reactant: 842410
fast: false
is: ENSCAFG00000002635.1
product: 842458
reactant: 842398
is: ENSCAFG00000023495.1
product: 842470
reactant: 842386
product: 842422
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal
reversible: true
is: ENSCAFG00000016446.2

750950
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Se-Adenosylselenomethionine_C15H23N6O5Se
type: Species

773147
stoichiometry: 1.0
species: 732441
type: SpeciesReference

823538
stoichiometry: 1.0
species: 739656
type: SpeciesReference

824385
stoichiometry: 1.0
species: 742467
type: SpeciesReference

832857
stoichiometry: 2.0
species: 745723
type: SpeciesReference

742369
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 15_C79H114N5O98S11X
type: Species

035179
fast: false
reversible: false
reactant: 796950
product: 796962
is: ENSCAFG00000004407.2
product: 796975
name: malic enzyme (NADP), mitochondrial
product: 796988
notes: R_ME2m subsystem: Pyruvate Metabolism R_ME2m equation: [m] : mal-L + nadp --> co2 + nadph + pyr
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.40
reactant: 796938

731694
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: S-Adenosyl-L-methionine_C15H23N6O5S
type: Species

735769
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Deoxycytidine_C9H13N3O4
type: Species

769944
stoichiometry: 1.0
species: 740301
type: SpeciesReference

786160
stoichiometry: 1.0
species: 749031
type: SpeciesReference

726900
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Deoxy-D-ribose 5-phosphate_C5H9O7P
type: Species

034468
is: ENSCAFG00000004818.2
reactant: 789978
fast: false
product: 790017
product: 790004
product: 790066
product: 789991
reactant: 789928
product: 790029
reactant: 789916
reactant: 789940
reactant: 789965
notes: R_BTNt3i subsystem: Transport, Extracellular R_BTNt3i equation: atp[c] + btn[e] + h2o[c] + (2) na1[e] --> adp[c] + btn[c] + h[c] + (2) na1[c] + pi[c] R_LIPOti subsystem: Transport, Extracellular R_LIPOti equation: atp[c] + h2o[c] + lipoate[e] + (2) na1[e] --> adp[c] + h[c] + lipoate[c] + (2) na1[c] + pi[c] R_PNTOt5 subsystem: Transport, Extracellular R_PNTOt5 equation: atp[c] + h2o[c] + (2) na1[e] + pnto-R[e] --> adp[c] + h[c] + (2) na1[c] + pi[c] + pnto-R[c]
type: Reaction
reactant: 789952
product: 790041
reversible: false
product: 790054

816173
stoichiometry: 1.0
species: 745399
type: SpeciesReference

807905
stoichiometry: 1.0
species: 730124
type: SpeciesReference

828796
stoichiometry: 1.0
species: 739462
type: SpeciesReference

836640
stoichiometry: 2.0
species: 741283
type: SpeciesReference

727552
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _3-Methylbut-2-enoyl-CoA_C26H38N7O17P3S
type: Species

751010
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenohomocysteine_C4H9NO2Se
type: Species

820812
stoichiometry: 1.0
species: 735938
type: SpeciesReference

775089
stoichiometry: 18.0
species: 741187
type: SpeciesReference

727142
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4
type: Species

788312
stoichiometry: 1.0
species: 739815
type: SpeciesReference

855243
stoichiometry: 1.0
species: 726900
type: SpeciesReference

760042
stoichiometry: 3.0
species: 741151
type: SpeciesReference

739705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: GDP_C10H12N5O11P2
type: Species

762361
stoichiometry: 1.0
species: 749707
type: SpeciesReference

824917
stoichiometry: 1.0
species: 748121
type: SpeciesReference

813144
stoichiometry: 1.0
species: 741151
type: SpeciesReference

806953
stoichiometry: 1.0
species: 737798
type: SpeciesReference

791051
stoichiometry: 1.0
species: 747638
type: SpeciesReference

827269
stoichiometry: 1.0
species: 745988
type: SpeciesReference

839137
stoichiometry: 1.0
species: 740180
type: SpeciesReference

806737
stoichiometry: 1.0
species: 741308
type: SpeciesReference

757675
stoichiometry: 2.0
species: 746930
type: SpeciesReference

755610
stoichiometry: 1.0
species: 748675
type: SpeciesReference

793090
stoichiometry: 1.0
species: 745747
type: SpeciesReference

844253
stoichiometry: 5.0
species: 746978
type: SpeciesReference

838885
stoichiometry: 1.0
species: 742940
type: SpeciesReference

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stoichiometry: 1.0
species: 733981
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Nitrophenyl sulfate_C6H4NO6S
type: Species

847378
stoichiometry: 1.0
species: 728800
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Coenzyme A_C21H32N7O16P3S
type: Species

037375
notes: R_MI145PK subsystem: Inositol Phosphate Metabolism R_MI145PK equation: [c] : atp + mi145p --> adp + h + mi1345p
reactant: 817583
is: http://identifiers.org/ec-code/2.7.1.127
name: inositol-1,4,5-trisphosphate 3-kinase
product: 817632
is: ENSCAFG00000009562.2
product: 817607
product: 817620
fast: false
type: Reaction
reversible: false
reactant: 817595
is: ENSCAFG00000016055.2
is: ENSCAFG00000005104.2

798018
stoichiometry: 1.0
species: 752642
type: SpeciesReference

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reactant: 762155
notes: R_SMS subsystem: Sphingolipid Metabolism R_SMS equation: [c] : crm_hs + pchol_hs --> dag_hs + sphmyln_hs
is: ENSCAFG00000015628.2
fast: false
type: Reaction
product: 762179
reactant: 762167
product: 762191
name: Sphingomyelin synthase (homo sapiens)
reversible: false

839715
stoichiometry: 1.0
species: 751178
type: SpeciesReference

734223
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: coumarin_C9H6O2
type: Species

851273
stoichiometry: 1.0
species: 740663
type: SpeciesReference

829590
stoichiometry: 1.0
species: 749502
type: SpeciesReference

808890
stoichiometry: 1.0
species: 741308
type: SpeciesReference

764034
stoichiometry: 6.0
species: 733933
type: SpeciesReference

773003
stoichiometry: 1.0
species: 735155
type: SpeciesReference

040887
is: ENSCAFG00000017838.2
reactant: 853025
name: cytochrome P450, family 46, subfamily A, polypeptide 1
notes: R_P45046A1r subsystem: Bile Acid Biosynthesis R_P45046A1r equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol24oh
product: 853073
fast: false
reversible: false
reactant: 853049
type: Reaction
product: 853085
product: 853061
reactant: 853013
reactant: 853037

759378
stoichiometry: 1.0
species: 748711
type: SpeciesReference

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stoichiometry: 2.0
species: 738039
type: SpeciesReference

826299
stoichiometry: 4.0
species: 730922
type: SpeciesReference

778662
stoichiometry: 1.0
species: 751627
type: SpeciesReference

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stoichiometry: 1.0
species: 728366
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: VI2Fuc-nLc6_C64H112N3O36FULLRCO
type: Species

853410
stoichiometry: 1.0
species: 731755
type: SpeciesReference

811036
stoichiometry: 4.0
species: 741235
type: SpeciesReference

754874
stoichiometry: 1.0
species: 749755
type: SpeciesReference

729662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total_CO2FULLR
type: Species

842458
stoichiometry: 1.0
species: 750526
type: SpeciesReference

825736
stoichiometry: 2.0
species: 741139
type: SpeciesReference

810687
stoichiometry: 2.0
species: 747307
type: SpeciesReference

781770
stoichiometry: 1.0
species: 746315
type: SpeciesReference

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reversible: true
is: ENSCAFG00000005751.2
fast: false
product: 845184
product: 845172
is: ENSCAFG00000004623.2
is: ENSCAFG00000014228.2
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type: Reaction
reactant: 845148
is: ENSCAFG00000015723.2
name: bicarbonate transport (Cl-/HCO3- exchange)
reactant: 845160

754233
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Xanthosine_C10H12N4O6
type: Species

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stoichiometry: 1.0
species: 726937
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 19_C171H275N12O137S5X
type: Species

740193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Glycine_C2H5NO2
type: Species

830849
stoichiometry: 1.0
species: 741308
type: SpeciesReference

765988
stoichiometry: 1.0
species: 752133
type: SpeciesReference

735721
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dCTP_C9H12N3O13P3
type: Species

737055
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyribose_C5H10O4
type: Species

797602
stoichiometry: 1.0
species: 735433
type: SpeciesReference

808722
stoichiometry: 2.0
species: 748483
type: SpeciesReference

817198
stoichiometry: 1.0
species: 754123
type: SpeciesReference

779892
stoichiometry: 1.0
species: 750926
type: SpeciesReference

769566
stoichiometry: 1.0
species: 742357
type: SpeciesReference

827990
stoichiometry: 1.0
species: 740762
type: SpeciesReference

037798
product: 822791
product: 822827
reversible: false
reactant: 822743
is: ENSCAFG00000001937.2
product: 822815
reactant: 822755
reactant: 822731
fast: false
is: ENSCAFG00000013713.2
reactant: 822719
product: 822803
notes: R_GLYKm subsystem: Glycerophospholipid Metabolism R_GLYKm equation: [m] : atp + glyc --> adp + glyc3p + h R_GLYK subsystem: Glycerophospholipid Metabolism R_GLYK equation: [c] : atp + glyc --> adp + glyc3p + h
product: 822779
is: http://identifiers.org/ec-code/2.7.1.30
product: 822767
type: Reaction
is: ENSCAFG00000000233.2

785476
stoichiometry: 2.0
species: 751082
type: SpeciesReference

807688
stoichiometry: 1.0
species: 746978
type: SpeciesReference

846706
stoichiometry: 1.0
species: 742236
type: SpeciesReference

756176
stoichiometry: 1.0
species: 742856
type: SpeciesReference

036555
product: 809989
reactant: 809915
is: ENSCAFG00000003236.2
reversible: false
product: 810001
fast: false
is: ENSCAFG00000009041.2
product: 809977
is: http://identifiers.org/ec-code/3.1.3.36
product: 810025
reactant: 809940
is: http://identifiers.org/ec-code/3.1.3.56
is: ENSCAFG00000019664.2
reactant: 809928
product: 810013
reactant: 809953
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reactant: 809965
type: Reaction

831582
stoichiometry: 1.0
species: 736813
type: SpeciesReference

841076
stoichiometry: 1.0
species: 730124
type: SpeciesReference

041190
reversible: false
name: N-Acetyl-L-aspartate amidohydrolase
reactant: 855315
fast: false
type: Reaction
reactant: 855303
notes: R_NACASPAH subsystem: Alanine and Aspartate Metabolism R_NACASPAH equation: [c] : Nacasp + h2o --> ac + asp-L
is: ENSCAFG00000012360.2
product: 855327
is: http://identifiers.org/ec-code/3.5.1.15
product: 855339

734767
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 1_C45H66N2O49S4
type: Species

031174
is: ENSCAFG00000016098.2
fast: false
is: ENSCAFG00000003774.2
is: http://identifiers.org/ec-code/4.2.1.11
name: enolase
is: ENSCAFG00000019697.2
product: 761017
product: 761029
type: Reaction
reactant: 761005
reversible: true
notes: R_ENO subsystem: Glycolysis/Gluconeogenesis R_ENO equation: [c] : 2pg <==> h2o + pep
is: ENSCAFG00000015802.2

842001
stoichiometry: 1.0
species: 727034
type: SpeciesReference

786485
stoichiometry: 1.0
species: 730160
type: SpeciesReference

726802
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-2-Amino-3-oxobutanoate_C4H7NO3
type: Species

850466
stoichiometry: 1.0
species: 735601
type: SpeciesReference

831198
stoichiometry: 2.0
species: 727009
type: SpeciesReference

799545
stoichiometry: 1.0
species: 741199
type: SpeciesReference

831005
stoichiometry: 1.0
species: 741151
type: SpeciesReference

815244
stoichiometry: 1.0
species: 733467
type: SpeciesReference

784659
stoichiometry: 2.0
species: 749200
type: SpeciesReference

818497
stoichiometry: 1.0
species: 729883
type: SpeciesReference

740445
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: glycogen, structure 5 (glycogenin-2[1,4-Glc])_C12H21O11X
type: Species

761065
stoichiometry: 2.0
species: 735288
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Phenylpyruvate_C9H7O3
type: Species

763960
stoichiometry: 1.0
species: 750794
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Gal-Gal-Gal-Glc-Cer (homo sapiens)_C42H76NO22FULLRCO
type: Species

843697
stoichiometry: 1.0
species: 744534
type: SpeciesReference

783595
stoichiometry: 1.0
species: 727178
type: SpeciesReference

777830
stoichiometry: 1.0
species: 738774
type: SpeciesReference

792775
stoichiometry: 1.0
species: 746364
type: SpeciesReference

743564
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 5_C222H356N15O194S11
type: Species

836786
stoichiometry: 4.0
species: 733750
type: SpeciesReference

833627
stoichiometry: 3.0
species: 740180
type: SpeciesReference

846646
stoichiometry: 1.0
species: 734042
type: SpeciesReference

776710
stoichiometry: 1.0
species: 741199
type: SpeciesReference

817934
stoichiometry: 1.0
species: 730076
type: SpeciesReference

787784
stoichiometry: 1.0
species: 737702
type: SpeciesReference

770558
stoichiometry: 1.0
species: 736704
type: SpeciesReference

733141
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Cob(II)alamin_C62H92CoN13O14P
type: Species

755478
stoichiometry: 1.0
species: 735926
type: SpeciesReference

768721
stoichiometry: 2.0
species: 741308
type: SpeciesReference

745447
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human liver homolog_C1360H2228N20O270P20
type: Species

757127
stoichiometry: 1.0
species: 752181
type: SpeciesReference

801831
stoichiometry: 4.0
species: 753350
type: SpeciesReference

830301
stoichiometry: 5.0
species: 741296
type: SpeciesReference

031017
product: 759886
product: 759873
is: ENSCAFG00000014033.2
reactant: 759849
reactant: 759861
notes: R_PPA subsystem: Oxidative Phosphorylation R_PPA equation: [c] : h2o + ppi --> h + (2) pi
is: http://identifiers.org/ec-code/3.6.1.1
fast: false
reversible: false
name: inorganic diphosphatase
type: Reaction

758001
stoichiometry: 6.0
species: 749249
type: SpeciesReference

039983
name: Choline kinase
reactant: 842254
notes: R_CHOLK subsystem: Glycerophospholipid Metabolism R_CHOLK equation: [c] : atp + chol --> adp + cholp + h
is: http://identifiers.org/ec-code/2.7.1.32
type: Reaction
fast: false
reversible: false
product: 842290
is: ENSCAFG00000000579.2
product: 842266
reactant: 842242
product: 842278

783403
stoichiometry: 1.0
species: 742369
type: SpeciesReference

832148
stoichiometry: 1.0
species: 741259
type: SpeciesReference

813240
stoichiometry: 1.0
species: 741283
type: SpeciesReference

749514
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Diphosphate_HO7P2
type: Species

827882
stoichiometry: 1.0
species: 740542
type: SpeciesReference

841785
stoichiometry: 1.0
species: 741320
type: SpeciesReference

755201
stoichiometry: 1.0
species: 741452
type: SpeciesReference

769131
stoichiometry: 1.0
species: 733009
type: SpeciesReference

807796
stoichiometry: 1.0
species: 747503
type: SpeciesReference

747478
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: NMN_C11H14N2O8P
type: Species

817826
stoichiometry: 1.0
species: 752533
type: SpeciesReference

771517
stoichiometry: 1.0
species: 749466
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
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type: Species

732793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Biotinyl-5'-AMP_C20H27N7O9PS
type: Species

729198
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: heptaglutamyl folate (THF)_C49H57N13O24
type: Species

787892
stoichiometry: 1.0
species: 742758
type: SpeciesReference

764468
stoichiometry: 2.0
species: 754257
type: SpeciesReference

744712
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Lactaldehyde_C3H6O2
type: Species

842566
stoichiometry: 3.0
species: 747746
type: SpeciesReference

771890
stoichiometry: 1.0
species: 746291
type: SpeciesReference

803919
stoichiometry: 2.0
species: 741320
type: SpeciesReference

783983
stoichiometry: 1.0
species: 746882
type: SpeciesReference

756285
stoichiometry: 1.0
species: 741259
type: SpeciesReference

754668
stoichiometry: 1.0
species: 739486
type: SpeciesReference

814528
stoichiometry: 1.0
species: 726440
type: SpeciesReference

036446
is: http://identifiers.org/ec-code/2.8.2.23
is: ENSCAFG00000017700.2
fast: false
product: 809158
reactant: 809120
notes: R_S3T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T2g equation: [g] : hs_pre14 + paps --> h + hs_pre15 + pap
reversible: false
product: 809134
reactant: 809108
name: heparin-glucosamine 3-O-sulfotransferase
type: Reaction
product: 809146

779483
stoichiometry: 1.0
species: 727263
type: SpeciesReference

849695
stoichiometry: 4.0
species: 753338
type: SpeciesReference

808613
stoichiometry: 1.0
species: 736255
type: SpeciesReference

784394
stoichiometry: 2.0
species: 741259
type: SpeciesReference

786593
stoichiometry: 1.0
species: 750610
type: SpeciesReference

845271
stoichiometry: 1.0
species: 741259
type: SpeciesReference

745675
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

740554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: GMP_C10H12N5O8P
type: Species

754983
stoichiometry: 1.0
species: 747173
type: SpeciesReference

809410
stoichiometry: 1.0
species: 738546
type: SpeciesReference

833074
stoichiometry: 1.0
species: 745663
type: SpeciesReference

765204
stoichiometry: 1.0
species: 747698
type: SpeciesReference

726259
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25
type: Species

753145
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: UDP_C9H11N2O12P2
type: Species

840267
stoichiometry: 1.0
species: 737091
type: SpeciesReference

759063
stoichiometry: 1.0
species: 747074
type: SpeciesReference

761174
stoichiometry: 2.0
species: 753579
type: SpeciesReference

749237
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Phosphate_HO4P
type: Species

776867
stoichiometry: 1.0
species: 732152
type: SpeciesReference

782703
stoichiometry: 1.0
species: 738906
type: SpeciesReference

765319
stoichiometry: 1.0
species: 747002
type: SpeciesReference

738546
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Fucose 1-phosphate_C6H11O8P
type: Species

832256
stoichiometry: 1.0
species: 747173
type: SpeciesReference

804054
stoichiometry: 2.0
species: 747173
type: SpeciesReference

854098
stoichiometry: 1.0
species: 753157
type: SpeciesReference

855473
stoichiometry: 1.0
species: 730184
type: SpeciesReference

801723
stoichiometry: 1.0
species: 733714
type: SpeciesReference

830957
stoichiometry: 2.0
species: 740922
type: SpeciesReference

732417
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Aspartate_C4H6NO4
type: Species

758436
stoichiometry: 3.0
species: 746918
type: SpeciesReference

810579
stoichiometry: 1.0
species: 735336
type: SpeciesReference

790306
stoichiometry: 1.0
species: 753194
type: SpeciesReference

842737
stoichiometry: 1.0
species: 748567
type: SpeciesReference

793162
stoichiometry: 2.0
species: 745784
type: SpeciesReference

794043
stoichiometry: 1.0
species: 739901
type: SpeciesReference

843830
stoichiometry: 1.0
species: 744265
type: SpeciesReference

761428
stoichiometry: 1.0
species: 747698
type: SpeciesReference

811108
stoichiometry: 3.0
species: 741308
type: SpeciesReference

800750
stoichiometry: 1.0
species: 737991
type: SpeciesReference

775354
stoichiometry: 1.0
species: 728920
type: SpeciesReference

734658
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1_C31H47NO31S2X
type: Species

843080
stoichiometry: 1.0
species: 744796
type: SpeciesReference

761573
stoichiometry: 1.0
species: 737642
type: SpeciesReference

855327
stoichiometry: 1.0
species: 729979
type: SpeciesReference

741416
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Bicarbonate_CHO3
type: Species

805153
stoichiometry: 1.0
species: 753738
type: SpeciesReference

032535
is: http://identifiers.org/ec-code/2.5.1.26
name: alkylglycerone phosphate synthase
product: 774093
reversible: false
product: 774067
fast: false
reactant: 774041
is: ENSCAFG00000013522.2
reactant: 774054
type: Reaction
notes: R_AGPSx subsystem: Glycerophospholipid Metabolism R_AGPSx equation: [x] : adhap_hs + alkylR1oh --> Rtotal + akdhap_hs + h
product: 774080

737955
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Ethanol_C2H6O
type: Species

748133
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: octadecenoyl carnitine_C25H47NO4
type: Species

805008
stoichiometry: 1.0
species: 751615
type: SpeciesReference

829193
stoichiometry: 1.0
species: 747746
type: SpeciesReference

830609
stoichiometry: 1.0
species: 728607
type: SpeciesReference

764251
stoichiometry: 1.0
species: 738329
type: SpeciesReference

738690
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)3 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C70H122N3O40FULLRCO
type: Species

040997
is: http://identifiers.org/ec-code/1.11.1.7
reactant: 853747
product: 853783
name: Peroxidase (multiple substrates)
reversible: false
is: ENSCAFG00000017474.2
type: Reaction
notes: R_PRDXl subsystem: Miscellaneous R_PRDXl equation: [l] : h2o2 + meoh --> fald + (2) h2o
fast: false
reactant: 853759
product: 853771

733250
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2
type: Species

770667
stoichiometry: 3.0
species: 734127
type: SpeciesReference

777987
stoichiometry: 1.0
species: 738522
type: SpeciesReference

791883
stoichiometry: 2.0
species: 741416
type: SpeciesReference

835545
stoichiometry: 1.0
species: 739292
type: SpeciesReference

808782
stoichiometry: 1.0
species: 748435
type: SpeciesReference

834168
stoichiometry: 1.0
species: 728668
type: SpeciesReference

852784
stoichiometry: 1.0
species: 734308
type: SpeciesReference

843588
stoichiometry: 1.0
species: 749249
type: SpeciesReference

833518
stoichiometry: 1.0
species: 733957
type: SpeciesReference

777384
stoichiometry: 1.0
species: 741259
type: SpeciesReference

762010
stoichiometry: 1.0
species: 750369
type: SpeciesReference

782931
stoichiometry: 2.0
species: 747185
type: SpeciesReference

742091
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 18_C43H66N2O45S3
type: Species

828640
stoichiometry: 1.0
species: 752803
type: SpeciesReference

752842
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: L-Tryptophan_C11H12N2O2
type: Species

853206
stoichiometry: 1.0
species: 739015
type: SpeciesReference

748411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2
type: Species

736547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: dITP_C10H11N4O13P3
type: Species

834751
stoichiometry: 1.0
species: 739815
type: SpeciesReference

806521
stoichiometry: 1.0
species: 739656
type: SpeciesReference

037931
is: ENSCAFG00000014895.2
product: 824180
is: http://identifiers.org/ec-code/2.7.1.6
fast: false
notes: R_GALK subsystem: Galactose metabolism R_GALK equation: [c] : atp + gal --> adp + gal1p + h
reversible: false
type: Reaction
product: 824155
name: galactokinase
reactant: 824131
product: 824168
is: ENSCAFG00000004914.2
reactant: 824143

789119
stoichiometry: 1.0
species: 736547
type: SpeciesReference

786052
stoichiometry: 1.0
species: 740168
type: SpeciesReference

848679
stoichiometry: 1.0
species: 734585
type: SpeciesReference

761707
stoichiometry: 1.0
species: 737654
type: SpeciesReference

804911
stoichiometry: 1.0
species: 733835
type: SpeciesReference

818120
stoichiometry: 2.0
species: 748362
type: SpeciesReference

794464
stoichiometry: 1.0
species: 751542
type: SpeciesReference

825664
stoichiometry: 2.0
species: 747758
type: SpeciesReference

785608
stoichiometry: 1.0
species: 732404
type: SpeciesReference

773257
stoichiometry: 1.0
species: 752569
type: SpeciesReference

845123
stoichiometry: 1.0
species: 730922
type: SpeciesReference

802036
stoichiometry: 1.0
species: 749960
type: SpeciesReference

745555
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1540H2528N20O420P20
type: Species

850875
stoichiometry: 1.0
species: 745832
type: SpeciesReference

816065
stoichiometry: 1.0
species: 753579
type: SpeciesReference

037074
reactant: 814196
product: 814260
product: 814234
reactant: 814170
product: 814247
type: Reaction
is: http://identifiers.org/ec-code/6.2.1.5
product: 814286
product: 814273
reactant: 814208
fast: false
notes: R_SUCOASm subsystem: Citric Acid Cycle R_SUCOASm equation: [m] : atp + coa + succ <==> adp + pi + succoa R_MECOALm subsystem: C5-Branched dibasic acid metabolism R_MECOALm equation: [m] : atp + coa + mescon <==> adp + mescoa + pi R_ITCOALm subsystem: C5-Branched dibasic acid metabolism R_ITCOALm equation: [m] : atp + coa + itacon <==> adp + itaccoa + pi
reversible: true
is: ENSCAFG00000004454.2
reactant: 814221
reactant: 814183

846936
stoichiometry: 17.0
species: 751227
type: SpeciesReference

846402
stoichiometry: 1.0
species: 749430
type: SpeciesReference

845027
stoichiometry: 1.0
species: 742782
type: SpeciesReference

845968
stoichiometry: 1.0
species: 728908
type: SpeciesReference

038465
product: 829374
reversible: false
product: 829386
notes: R_AGTim subsystem: Alanine and Aspartate Metabolism R_AGTim equation: [m] : ala-L + glx --> gly + pyr
name: alanine-glyoxylate transaminase (irreversible), mitochondrial
reactant: 829349
type: Reaction
is: ENSCAFG00000011314.2
reactant: 829361
is: http://identifiers.org/ec-code/2.6.1.44
is: ENSCAFG00000018790.2
fast: false

851116
stoichiometry: 1.0
species: 750454
type: SpeciesReference

750044
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin F2alpha_C20H33O5
type: Species

727202
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _3',5'-Cyclic GMP_C10H11N5O7P
type: Species

844035
stoichiometry: 23.0
species: 753157
type: SpeciesReference

791257
stoichiometry: 1.0
species: 727684
type: SpeciesReference

774277
stoichiometry: 1.0
species: 746134
type: SpeciesReference

827570
stoichiometry: 1.0
species: 741308
type: SpeciesReference

811468
stoichiometry: 5.0
species: 735228
type: SpeciesReference

823647
stoichiometry: 9.0
species: 735553
type: SpeciesReference

792547
stoichiometry: 1.0
species: 741308
type: SpeciesReference

747794
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Superoxide anion_O2
type: Species

742212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 3_C81H117N5O97S10
type: Species

769674
stoichiometry: 8.0
species: 748687
type: SpeciesReference

785055
stoichiometry: 1.0
species: 747074
type: SpeciesReference

813035
stoichiometry: 1.0
species: 727929
type: SpeciesReference

820920
stoichiometry: 1.0
species: 735709
type: SpeciesReference

034312
reactant: 788746
product: 788854
product: 788866
reactant: 788782
reactant: 788734
reactant: 788698
product: 788818
product: 788830
product: 788794
is: ENSCAFG00000016901.2
product: 788842
is: http://identifiers.org/ec-code/1.2.1.21
is: http://identifiers.org/ec-code/1.2.1.27
reactant: 788722
reactant: 788770
reversible: false
reactant: 788710
product: 788806
product: 788878
notes: R_MMSAD3m subsystem: Propanoate Metabolism R_MMSAD3m equation: [m] : coa + msa + nad --> accoa + co2 + nadh R_MMSAD1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMSAD1m equation: [m] : 2mop + coa + nad --> co2 + nadh + ppcoa R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh
type: Reaction
reactant: 788758
fast: false

785888
stoichiometry: 1.0
species: 741765
type: SpeciesReference

035840
product: 803278
type: Reaction
fast: false
product: 803314
is: http://identifiers.org/ec-code/6.4.1.3
is: ENSCAFG00000005838.2
reactant: 803242
notes: R_PPCOACm subsystem: Valine, Leucine, and Isoleucine Metabolism R_PPCOACm equation: [m] : atp + hco3 + ppcoa --> adp + h + mmcoa-S + pi
reversible: false
reactant: 803266
product: 803302
product: 803290
name: Propionyl-CoA carboxylase, mitochondrial
reactant: 803254

847056
stoichiometry: 1.0
species: 744133
type: SpeciesReference

039080
reactant: 833976
reversible: false
modifier: 834048
product: 834000
fast: false
reactant: 833964
type: Reaction
is: http://identifiers.org/ec-code/1.5.1.3
modifier: 834024
is: ENSCAFG00000001201.2
notes: R_DHFR subsystem: Folate Metabolism R_DHFR equation: [c] : dhf + h + nadph <==> nadp + thf R_FOLR2 subsystem: Folate Metabolism R_FOLR2 equation: [c] : fol + nadph --> dhf + nadp
modifier: 834036
product: 833988
modifier: 834060
modifier: 834012

762470
stoichiometry: 1.0
species: 733618
type: SpeciesReference

840895
stoichiometry: 116.0
species: 730148
type: SpeciesReference

821799
stoichiometry: 1.0
species: 730922
type: SpeciesReference

848017
stoichiometry: 35.0
species: 734127
type: SpeciesReference

767351
stoichiometry: 4.0
species: 730922
type: SpeciesReference

850899
stoichiometry: 4.0
species: 749658
type: SpeciesReference

038318
product: 828098
fast: false
reactant: 828026
type: Reaction
reactant: 828062
product: 828110
reactant: 828086
reactant: 828050
reversible: false
product: 828134
product: 828158
product: 828122
reactant: 828038
product: 828146
is: ENSCAFG00000011224.2
reactant: 828074
is: http://identifiers.org/ec-code/1.4.3.3
notes: R_DPROOp subsystem: Arginine and Proline Metabolism R_DPROOp equation: [x] : o2 + pro-D --> 1p2cbxl + h + h2o2 R_DALAOXx subsystem: D-alanine metabolism R_DALAOXx equation: [x] : ala-D + h2o + o2 --> h2o2 + nh4 + pyr R_DARGOp subsystem: D-arg and D-orn metabolism R_DARGOp equation: [x] : arg-D + h2o + o2 --> 5g2oxpt + h2o2 + nh4 R_DORNOp subsystem: D-arg and D-orn metabolism R_DORNOp equation: [x] : h2o + o2 + orn-D --> 5a2opntn + h2o2 + nh4
product: 828170

735877
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: debrisoquine_C10H14N3
type: Species

838993
stoichiometry: 1.0
species: 749297
type: SpeciesReference

750610
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Retinol_C20H30O
type: Species

822875
stoichiometry: 1.0
species: 732901
type: SpeciesReference

831908
stoichiometry: 1.0
species: 749249
type: SpeciesReference

797795
stoichiometry: 1.0
species: 729537
type: SpeciesReference

040344
fast: false
reactant: 845595
product: 846088
reactant: 845824
product: 846112
reactant: 845812
reactant: 845680
product: 846052
reactant: 845716
reactant: 845728
reactant: 845631
reactant: 845704
notes: R_FPGS subsystem: Folate Metabolism R_FPGS equation: [c] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS9 subsystem: Folate Metabolism R_FPGS9 equation: [c] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS3m subsystem: Folate Metabolism R_FPGS3m equation: [m] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS7 subsystem: Folate Metabolism R_FPGS7 equation: [c] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGSm subsystem: Folate Metabolism R_FPGSm equation: [m] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS4 subsystem: Folate Metabolism R_FPGS4 equation: [c] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS4m subsystem: Folate Metabolism R_FPGS4m equation: [m] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS6 subsystem: Folate Metabolism R_FPGS6 equation: [c] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS3 subsystem: Folate Metabolism R_FPGS3 equation: [c] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS5m subsystem: Folate Metabolism R_FPGS5m equation: [m] : 5dhf + atp + glu-L --> 6dhf + adp + h + pi R_FPGS2m subsystem: Folate Metabolism R_FPGS2m equation: [m] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS8 subsystem: Folate Metabolism R_FPGS8 equation: [c] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS2 subsystem: Folate Metabolism R_FPGS2 equation: [c] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS7m subsystem: Folate Metabolism R_FPGS7m equation: [m] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGS6m subsystem: Folate Metabolism R_FPGS6m equation: [m] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS9m subsystem: Folate Metabolism R_FPGS9m equation: [m] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS8m subsystem: Folate Metabolism R_FPGS8m equation: [m] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS5 subsystem: Folate Metabolism R…
product: 846100
product: 846004
type: Reaction
product: 845872
product: 846076
product: 846040
reactant: 845752
is: http://identifiers.org/ec-code/6.3.2.17
product: 845968
reactant: 845740
reversible: false
product: 846028
product: 845836
reactant: 845788
product: 845944
reactant: 845583
product: 845896
reactant: 845571
product: 845920
reactant: 845800
product: 845980
reactant: 845764
reactant: 845655
product: 846016
reactant: 845643
reactant: 845692
is: ENSCAFG00000009274.2
product: 846064
product: 845908
reactant: 845776
product: 845884
product: 845848
product: 845860
product: 845992
product: 845956
reactant: 845619
reactant: 845668
product: 845932
reactant: 845607

792330
stoichiometry: 1.0
species: 752878
type: SpeciesReference

839606
stoichiometry: 1.0
species: 745591
type: SpeciesReference

816753
stoichiometry: 1.0
species: 734646
type: SpeciesReference

035912
is: ENSCAFG00000009253.2
type: Reaction
reactant: 803846
is: ENSCAFG00000023181.1
reactant: 803833
is: ENSCAFG00000007279.2
is: ENSCAFG00000013011.2
is: http://identifiers.org/ec-code/3.1.4.17
is: ENSCAFG00000010425.2
is: ENSCAFG00000014928.2
is: ENSCAFG00000000239.2
product: 803858
product: 803870
fast: false
reversible: false
is: ENSCAFG00000017790.2
notes: R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h
name: _3',5'-cyclic-nucleotide phosphodiesterase
is: ENSCAFG00000007100.2

778770
stoichiometry: 1.0
species: 748170
type: SpeciesReference

765877
stoichiometry: 1.0
species: 752061
type: SpeciesReference

034987
reactant: 794670
product: 794707
notes: R_34HPPOR subsystem: Tyrosine metabolism R_34HPPOR equation: [c] : 34hpp + o2 --> co2 + hgentis R_PPOR subsystem: Phenylalanine metabolism R_PPOR equation: [c] : o2 + phpyr --> 2hyoxplac + co2
product: 794695
product: 794682
reactant: 794646
fast: false
reactant: 794658
is: ENSCAFG00000008093.2
is: http://identifiers.org/ec-code/1.13.11.27
type: Reaction
reversible: false

757054
stoichiometry: 2.0
species: 735673
type: SpeciesReference

757783
stoichiometry: 2.0
species: 747050
type: SpeciesReference

794319
stoichiometry: 1.0
species: 740265
type: SpeciesReference

728390
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5,6-Dihydrothymine_C5H8N2O2
type: Species

830531
stoichiometry: 1.0
species: 747734
type: SpeciesReference

838217
stoichiometry: 1.0
species: 747185
type: SpeciesReference

798872
stoichiometry: 7.0
species: 737374
type: SpeciesReference

847269
stoichiometry: 1.0
species: 753109
type: SpeciesReference

743120
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 10_C188H302N13O163S9
type: Species

835268
stoichiometry: 1.0
species: 730355
type: SpeciesReference

836532
stoichiometry: 1.0
species: 742758
type: SpeciesReference

755767
stoichiometry: 1.0
species: 741151
type: SpeciesReference

825964
stoichiometry: 1.0
species: 735601
type: SpeciesReference

795310
stoichiometry: 1.0
species: 747002
type: SpeciesReference

767798
stoichiometry: 1.0
species: 748037
type: SpeciesReference

765023
stoichiometry: 1.0
species: 744598
type: SpeciesReference

766268
stoichiometry: 1.0
species: 741596
type: SpeciesReference

754524
stoichiometry: 3.0
species: 741187
type: SpeciesReference

033185
reactant: 779012
reactant: 779037
reactant: 779024
notes: R_P4507B11r subsystem: Bile Acid Biosynthesis R_P4507B11r equation: [r] : h + nadph + o2 + xol25oh --> h2o + nadp + xoltri25 R_P4507B12r subsystem: Bile Acid Biosynthesis R_P4507B12r equation: [r] : h + nadph + o2 + xol27oh --> h2o + nadp + xoltri27
product: 779049
product: 779061
product: 779073
reactant: 778988
is: ENSCAFG00000007246.2
fast: false
type: Reaction
product: 779085
reactant: 779000
reversible: false

732623
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Bilirubin beta-diglucuronide_C45H50N4O18
type: Species

847281
stoichiometry: 1.0
species: 749466
type: SpeciesReference

728716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxy-N-formylkynurenine_C11H12N2O5
type: Species

780265
stoichiometry: 1.0
species: 726608
type: SpeciesReference

831354
stoichiometry: 1.0
species: 745964
type: SpeciesReference

769506
stoichiometry: 1.0
species: 731634
type: SpeciesReference

819510
stoichiometry: 1.0
species: 744362
type: SpeciesReference

832580
stoichiometry: 1.0
species: 730585
type: SpeciesReference

818133
stoichiometry: 1.0
species: 744637
type: SpeciesReference

030825
product: 758110
notes: R_MDHm subsystem: Citric Acid Cycle R_MDHm equation: [m] : mal-L + nad <==> h + nadh + oaa R_SLDxm subsystem: Cysteine Metabolism R_SLDxm equation: [m] : nad + sl-L <==> 3spyr + h + nadh
is: http://identifiers.org/ec-code/1.1.1.37
type: Reaction
product: 758074
reactant: 758062
fast: false
reactant: 758050
is: http://identifiers.org/ec-code/1.1.1.272
product: 758086
reversible: true
reactant: 758037
product: 758098
is: ENSCAFG00000010414.2

763840
stoichiometry: 2.0
species: 733933
type: SpeciesReference

855533
stoichiometry: 1.0
species: 753072
type: SpeciesReference

032126
product: 769944
product: 769968
is: http://identifiers.org/ec-code/1.1.1.27
modifier: 770185
reactant: 769895
modifier: 770052
is: ENSCAFG00000009211.2
type: Reaction
modifier: 770040
modifier: 770137
reactant: 769843
modifier: 769980
modifier: 770113
fast: false
modifier: 770101
modifier: 770089
is: ENSCAFG00000004928.2
reactant: 769856
reversible: false
modifier: 770173
modifier: 769992
modifier: 770125
modifier: 770028
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_LDH_Lm subsystem: Pyruvate Metabolism R_LDH_Lm equation: [m] : lac-L + nad <==> h + nadh + pyr R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa R_CREATt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_CREATt4_LPAREN_2_RPAREN_r equation: creat[e] + (2) na1[e] <==> creat[c] + (2) na1[c]
product: 769932
is: http://identifiers.org/ec-code/1.2.3.5
product: 769956
modifier: 770077
is: ENSCAFG00000006066.2
is: ENSCAFG00000002071.2
reactant: 769869
reactant: 769882
reactant: 769908
modifier: 770161
modifier: 770064
product: 769920
modifier: 770149
modifier: 770016
modifier: 770004

744940
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: lignoceric acid_C24H47O2
type: Species

800544
stoichiometry: 1.0
species: 745916
type: SpeciesReference

778758
stoichiometry: 1.0
species: 740433
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 4-linked), degradation product 4_C66H108N6O48SX
type: Species

749140
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _2-Hydroxyphytanoyl-CoA_C41H70N7O18P3S
type: Species

786388
stoichiometry: 1.0
species: 734018
type: SpeciesReference

754680
stoichiometry: 1.0
species: 749779
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-beta-D-Glucosyl-2-hydroxycinnamate_C15H18O8
type: Species

822586
stoichiometry: 2.0
species: 737618
type: SpeciesReference

820546
stoichiometry: 2.0
species: 739656
type: SpeciesReference

768186
stoichiometry: 1.0
species: 740120
type: SpeciesReference

804284
stoichiometry: 1.0
species: 753047
type: SpeciesReference

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stoichiometry: 1.0
species: 732441
type: SpeciesReference

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stoichiometry: 1.0
species: 741283
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
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type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Choline phosphate_C5H13NO4P
type: Species

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stoichiometry: 1.0
species: 731549
type: SpeciesReference

039298
product: 836822
reactant: 836762
reactant: 836750
product: 836798
reactant: 836786
product: 836810
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reversible: true
is: ENSCAFG00000000637.2
fast: false
reactant: 836774
is: ENSCAFG00000014211.2
type: Reaction
product: 836834

805213
stoichiometry: 5.0
species: 741151
type: SpeciesReference

769830
stoichiometry: 1.0
species: 735047
type: SpeciesReference

791461
stoichiometry: 1.0
species: 732937
type: SpeciesReference

838145
stoichiometry: 1.0
species: 728414
type: SpeciesReference

840556
stoichiometry: 1.0
species: 736692
type: SpeciesReference

757807
stoichiometry: 1.0
species: 741151
type: SpeciesReference

821330
stoichiometry: 1.0
species: 753447
type: SpeciesReference

802820
stoichiometry: 2.0
species: 739987
type: SpeciesReference

771722
stoichiometry: 1.0
species: 746303
type: SpeciesReference

773583
stoichiometry: 1.0
species: 735228
type: SpeciesReference

812625
stoichiometry: 1.0
species: 739987
type: SpeciesReference

842470
stoichiometry: 3.0
species: 747173
type: SpeciesReference

770365
stoichiometry: 1.0
species: 748687
type: SpeciesReference

848161
stoichiometry: 1.0
species: 752181
type: SpeciesReference

822430
stoichiometry: 1.0
species: 728354
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: acyl carrier protein_C11H21N2O7PRS
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 26_C199H318N14O166S8X
type: Species

774737
stoichiometry: 1.0
species: 734321
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2
type: Species

838421
stoichiometry: 1.0
species: 736837
type: SpeciesReference

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stoichiometry: 1.0
species: 741560
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: D-Fructose_C6H12O6
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808457
stoichiometry: 1.0
species: 741765
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Sodium_Na
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stoichiometry: 2.0
species: 733009
type: SpeciesReference

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stoichiometry: 1.0
species: 747577
type: SpeciesReference

781216
stoichiometry: 4.0
species: 751214
type: SpeciesReference

827558
stoichiometry: 1.0
species: 751892
type: SpeciesReference

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stoichiometry: 13.0
species: 741151
type: SpeciesReference

740349
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Glycolate_C2H3O3
type: Species

776031
stoichiometry: 3.0
species: 746918
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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stoichiometry: 41.0
species: 730427
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Imidazole-4-acetate_C5H5N2O2
type: Species

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stoichiometry: 2.0
species: 747173
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: sialyl (2,3) sialyl (2,6) galactosylgloboside (homo sapiens)_C72H121N4O43FULLRCO
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Calcium_Ca
type: Species

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stoichiometry: 1.0
species: 733335
type: SpeciesReference

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stoichiometry: 1.0
species: 754305
type: SpeciesReference

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stoichiometry: 1.0
species: 753084
type: SpeciesReference

735457
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: dAMP_C10H12N5O6P
type: Species

751227
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Sulfate_O4S
type: Species

771661
stoichiometry: 1.0
species: 738123
type: SpeciesReference

815702
stoichiometry: 5.0
species: 741283
type: SpeciesReference

760796
stoichiometry: 1.0
species: 737798
type: SpeciesReference

829722
stoichiometry: 1.0
species: 741332
type: SpeciesReference

797946
stoichiometry: 1.0
species: 749297
type: SpeciesReference

771457
stoichiometry: 1.0
species: 730669
type: SpeciesReference

796224
stoichiometry: 1.0
species: 754343
type: SpeciesReference

793906
stoichiometry: 1.0
species: 726754
type: SpeciesReference

037508
is: http://identifiers.org/ec-code/1.4.3.1
reactant: 819064
reactant: 819088
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product: 819112
product: 819100
product: 819124
name: D-aspartate oxidase, peroxisomal
type: Reaction
fast: false
is: ENSCAFG00000006437.2
reactant: 819076
reversible: false

845776
stoichiometry: 1.0
species: 752374
type: SpeciesReference

746557
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 3-phosphate_C6H11O9P
type: Species

770827
stoichiometry: 1.0
species: 731561
type: SpeciesReference

734091
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Coenzyme A_C21H32N7O16P3S
type: Species

823986
stoichiometry: 1.0
species: 744447
type: SpeciesReference

789855
stoichiometry: 1.0
species: 737508
type: SpeciesReference

780482
stoichiometry: 1.0
species: 752667
type: SpeciesReference

038004
reactant: 825580
product: 825604
is: http://identifiers.org/ec-code/6.2.1.3
fast: false
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reversible: false
is: ENSCAFG00000010928.2
type: Reaction
product: 825640
product: 825616
reactant: 825555
reactant: 825592
reactant: 825567
product: 825628

034757
fast: false
is: ENSCAFG00000005132.2
reactant: 792871
reversible: false
product: 792907
product: 792895
product: 792919
reactant: 792859
reactant: 792883
product: 792931
type: Reaction
is: http://identifiers.org/ec-code/2.4.99.3
notes: R_NS26T2g subsystem: O-Glycan Biosynthesis R_NS26T2g equation: [g] : cmpacna + sT_antigen --> cmp + dsT_antigen + h R_NS26Tg subsystem: O-Glycan Biosynthesis R_NS26Tg equation: [g] : Tn_antigen + cmpacna --> cmp + h + sTn_antigen

737386
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dUTP_C9H11N2O14P3
type: Species

819124
stoichiometry: 1.0
species: 747355
type: SpeciesReference

816488
stoichiometry: 1.0
species: 735360
type: SpeciesReference

757284
stoichiometry: 1.0
species: 748109
type: SpeciesReference

774119
stoichiometry: 1.0
species: 738015
type: SpeciesReference

823093
stoichiometry: 1.0
species: 731755
type: SpeciesReference

798450
stoichiometry: 1.0
species: 745109
type: SpeciesReference

833494
stoichiometry: 2.0
species: 735155
type: SpeciesReference

785912
stoichiometry: 1.0
species: 731561
type: SpeciesReference

789433
stoichiometry: 1.0
species: 741753
type: SpeciesReference

034480
reactant: 790114
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reversible: false
fast: false
product: 790126
is: ENSCAFG00000018706.2
reactant: 790102
type: Reaction
product: 790162
reactant: 790078
product: 790174
reactant: 790090
product: 790138
product: 790150

842194
stoichiometry: 1.0
species: 730524
type: SpeciesReference

034541
product: 790907
reactant: 790883
is: http://identifiers.org/ec-code/3.2.2.6
product: 790943
is: ENSCAFG00000015298.2
is: http://identifiers.org/ec-code/3.2.2.5
reactant: 790859
product: 790931
product: 790919
reversible: false
product: 790895
notes: R_NADNe subsystem: NAD Metabolism R_NADNe equation: [e] : h2o + nad --> adprib + h + ncam R_ADPRIBt subsystem: Transport, Extracellular R_ADPRIBt equation: adprib[e] --> adprib[c] R_NADPNe subsystem: NAD Metabolism R_NADPNe equation: [e] : h2o + nadp --> adprbp + h + ncam
fast: false
type: Reaction
reactant: 790847
reactant: 790871

825892
stoichiometry: 1.0
species: 733859
type: SpeciesReference

821040
stoichiometry: 1.0
species: 748898
type: SpeciesReference

811962
stoichiometry: 1.0
species: 734005
type: SpeciesReference

845331
stoichiometry: 1.0
species: 750490
type: SpeciesReference

835027
stoichiometry: 1.0
species: 753218
type: SpeciesReference

822017
stoichiometry: 1.0
species: 727190
type: SpeciesReference

795298
stoichiometry: 1.0
species: 750393
type: SpeciesReference

766702
stoichiometry: 2.0
species: 741259
type: SpeciesReference

819630
stoichiometry: 1.0
species: 750806
type: SpeciesReference

750273
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pantetheine_C11H22N2O4S
type: Species

836918
stoichiometry: 1.0
species: 751917
type: SpeciesReference

742648
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
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type: Species

827100
stoichiometry: 1.0
species: 753157
type: SpeciesReference

814979
stoichiometry: 2.0
species: 734115
type: SpeciesReference

851545
stoichiometry: 1.0
species: 747698
type: SpeciesReference

768463
stoichiometry: 1.0
species: 741308
type: SpeciesReference

737189
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Oxidized dithiothreitol_C4H8O2S2
type: Species

030705
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name: adenosylmethionine decarboxylase
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reactant: 756677
reactant: 756665
type: Reaction
is: http://identifiers.org/ec-code/4.1.1.50
product: 756701
notes: R_ADMDC subsystem: Arginine and Proline Metabolism R_ADMDC equation: [c] : amet + h --> ametam + co2
reversible: false
product: 756689

843504
stoichiometry: 3.0
species: 733738
type: SpeciesReference

822707
stoichiometry: 6.0
species: 741332
type: SpeciesReference

762119
stoichiometry: 1.0
species: 744598
type: SpeciesReference

772822
stoichiometry: 1.0
species: 738123
type: SpeciesReference

834457
stoichiometry: 2.0
species: 741211
type: SpeciesReference

763524
stoichiometry: 1.0
species: 728535
type: SpeciesReference

802241
stoichiometry: 1.0
species: 741308
type: SpeciesReference

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stoichiometry: 1.0
species: 738087
type: SpeciesReference

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stoichiometry: 1.0
species: 741259
type: SpeciesReference

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stoichiometry: 1.0
species: 741006
type: SpeciesReference

802989
stoichiometry: 1.0
species: 731090
type: SpeciesReference

799955
stoichiometry: 1.0
species: 726500
type: SpeciesReference

824795
stoichiometry: 1.0
species: 745085
type: SpeciesReference

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stoichiometry: 1.0
species: 741151
type: SpeciesReference

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stoichiometry: 1.0
species: 734453
type: SpeciesReference

840689
stoichiometry: 1.0
species: 742612
type: SpeciesReference

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stoichiometry: 1.0
species: 741271
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: L-Glutamine_C5H10N2O3
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stoichiometry: 1.0
species: 733810
type: SpeciesReference

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stoichiometry: 1.0
species: 739559
type: SpeciesReference

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stoichiometry: 3.0
species: 741259
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: D-Glucose_C6H12O6
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035708
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type: Reaction
reactant: 802386
product: 802422
name: nicotinate-nucleotide diphosphorylase (carboxylating)
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product: 802398
product: 802410
reactant: 802361
is: ENSCAFG00000016950.2
fast: false
notes: R_NNDPR subsystem: NAD Metabolism R_NNDPR equation: [c] : (2) h + prpp + quln --> co2 + nicrnt + ppi
is: http://identifiers.org/ec-code/2.4.2.19

837928
stoichiometry: 2.0
species: 741151
type: SpeciesReference

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stoichiometry: 1.0
species: 747294
type: SpeciesReference

779279
stoichiometry: 1.0
species: 751434
type: SpeciesReference

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species: 727831
type: SpeciesReference

755044
stoichiometry: 1.0
species: 742272
type: SpeciesReference

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stoichiometry: 1.0
species: 743312
type: SpeciesReference

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stoichiometry: 1.0
species: 734054
type: SpeciesReference

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stoichiometry: 2.0
species: 750369
type: SpeciesReference

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stoichiometry: 1.0
species: 741211
type: SpeciesReference

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stoichiometry: 1.0
species: 746930
type: SpeciesReference

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stoichiometry: 2.0
species: 748687
type: SpeciesReference

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stoichiometry: 1.0
species: 742576
type: SpeciesReference

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stoichiometry: 2.0
species: 739003
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Glutamate_C5H8NO4
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stoichiometry: 2.0
species: 731285
type: SpeciesReference

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stoichiometry: 1.0
species: 752483
type: SpeciesReference

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stoichiometry: 1.0
species: 741283
type: SpeciesReference

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stoichiometry: 1.0
species: 744611
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Formyl-5-hydroxykynurenamine_C10H13N2O3
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species: 749200
type: SpeciesReference

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species: 726851
type: SpeciesReference

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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species: 734091
type: SpeciesReference

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species: 751856
type: SpeciesReference

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species: 739717
type: SpeciesReference

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species: 750128
type: SpeciesReference

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species: 730004
type: SpeciesReference

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3
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839835
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species: 745675
type: SpeciesReference

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species: 743192
type: SpeciesReference

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species: 747294
type: SpeciesReference

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species: 744712
type: SpeciesReference

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stoichiometry: 1.0
species: 738486
type: SpeciesReference

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stoichiometry: 1.0
species: 730452
type: SpeciesReference

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stoichiometry: 1.0
species: 739462
type: SpeciesReference

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stoichiometry: 1.0
species: 748747
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pristanoyl coa_C40H68N7O17P3S
type: Species

782595
stoichiometry: 1.0
species: 738414
type: SpeciesReference

MODEL1008120006
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reaction: 032402
species: 731948
species: 736243
species: 736801
reaction: 040260
species: 733503
species: 750695
species: 744096
species: 744700
reaction: 031753
species: 741947
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species: 733678
species: 729738
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reaction: 041154
species: 737215
reaction: 031717
reaction: 038489
species: 747613
species: 753834
reaction: 037460
species: 752569
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reaction: 038318
reaction: 031162
reaction: 036229
species: 727807
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reaction: 032078
species: 745435
reaction: 036965
species: 735999
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species: 743396
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reaction: 033209
species: 745868
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species: 751094
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reaction: 038064
species: 745880
reaction: 036338
species: 739987
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reaction: 040308
reaction: 037170
species: 746327
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reaction: 035119
species: 751687
reaction: 039695
reaction: 038876
reaction: 037435
species: 741995
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reaction: 033706

806160
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species: 730076
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species: 739815
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
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species: 746930
type: SpeciesReference

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species: 747233
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species: 735517
type: SpeciesReference

835135
stoichiometry: 1.0
species: 744012
type: SpeciesReference

781969
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species: 731369
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Elaidic carnitine_C25H47NO4
type: Species

797084
stoichiometry: 1.0
species: 743853
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031729
type: Reaction
reactant: 765620
product: 765644
name: choline dehydrogenase (FAD acceptor), mitochondrial
is: http://identifiers.org/ec-code/1.1.99.1
product: 765632
notes: R_CHOLD2m subsystem: Glycine, Serine, and Threonine Metabolism R_CHOLD2m equation: [m] : chol + fad --> betald + fadh2
fast: false
reversible: false
is: ENSCAFG00000008296.2
reactant: 765608

833386
stoichiometry: 2.0
species: 741320
type: SpeciesReference

038743
notes: R_GALT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALT2g equation: [g] : lxser + udpgal --> h + l2xser + udp
type: Reaction
product: 831330
reactant: 831294
reactant: 831306
is: http://identifiers.org/ec-code/2.4.1.134
product: 831342
product: 831318
reversible: false
is: ENSCAFG00000019318.2
fast: false
name: UDP-D-galactose:galactosylxylose galactosyltransferase, Golgi apparatus

789543
stoichiometry: 1.0
species: 753579
type: SpeciesReference

807219
stoichiometry: 1.0
species: 747173
type: SpeciesReference

736400
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

780590
stoichiometry: 1.0
species: 751591
type: SpeciesReference

819787
stoichiometry: 1.0
species: 743216
type: SpeciesReference

819232
stoichiometry: 3.0
species: 749200
type: SpeciesReference

728101
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4 hydroxy debrisoquine_C10H14N3O
type: Species

845980
stoichiometry: 1.0
species: 726247
type: SpeciesReference

040441
product: 847209
reactant: 847196
reactant: 847183
product: 847221
is: ENSCAFG00000017195.2
fast: false
notes: R_TRIODTHYt2 subsystem: Transport, Extracellular R_TRIODTHYt2 equation: triodthy[e] <==> triodthy[c] R_THYOXt2 subsystem: Transport, Extracellular R_THYOXt2 equation: thyox-L[e] <==> thyox-L[c]
type: Reaction
reversible: true

760635
stoichiometry: 1.0
species: 744229
type: SpeciesReference

746665
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S
type: Species

763634
stoichiometry: 1.0
species: 729585
type: SpeciesReference

803302
stoichiometry: 1.0
species: 730946
type: SpeciesReference

855038
stoichiometry: 1.0
species: 740812
type: SpeciesReference

839943
stoichiometry: 1.0
species: 747541
type: SpeciesReference

828832
stoichiometry: 1.0
species: 753157
type: SpeciesReference

805442
stoichiometry: 2.0
species: 741163
type: SpeciesReference

794103
stoichiometry: 1.0
species: 734755
type: SpeciesReference

751554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: stearidonic acid C18:4, n-3_C18H27O2
type: Species

746098
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: D-Mannose_C6H12O6
type: Species

780699
stoichiometry: 23.0
species: 741139
type: SpeciesReference

738111
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2
type: Species

803628
stoichiometry: 1.0
species: 741332
type: SpeciesReference

797337
stoichiometry: 1.0
species: 743672
type: SpeciesReference

808037
stoichiometry: 1.0
species: 751214
type: SpeciesReference

840798
stoichiometry: 1.0
species: 749309
type: SpeciesReference

802410
stoichiometry: 1.0
species: 733981
type: SpeciesReference

731900
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: androsterone glucuronide_C25H38O8
type: Species

765753
stoichiometry: 1.0
species: 732961
type: SpeciesReference

824155
stoichiometry: 1.0
species: 739111
type: SpeciesReference

034697
reactant: 792438
type: Reaction
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p R_PGMT subsystem: Glycolysis/Gluconeogenesis R_PGMT equation: [c] : g1p <==> g6p
reversible: true
product: 792474
is: http://identifiers.org/ec-code/5.4.2.8
reactant: 792450
product: 792462
is: http://identifiers.org/ec-code/5.4.2.2
is: ENSCAFG00000016249.2
fast: false

817523
stoichiometry: 1.0
species: 729846
type: SpeciesReference

735011
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3_C37H52NO43S4X
type: Species

733945
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: CMP-N-acetylneuraminate_C20H29N4O16P
type: Species

036131
reactant: 806857
reactant: 806845
reactant: 806833
type: Reaction
product: 806869
fast: false
notes: R_P5CRxm subsystem: Arginine and Proline Metabolism R_P5CRxm equation: [m] : 1pyr5c + (2) h + nadh --> nad + pro-L R_P5CRm subsystem: Arginine and Proline Metabolism R_P5CRm equation: [m] : 1pyr5c + (2) h + nadph --> nadp + pro-L
reactant: 806821
reversible: false
product: 806881
is: http://identifiers.org/ec-code/1.5.1.2
is: ENSCAFG00000005906.2
product: 806893

032823
notes: R_PROAKGOX1r subsystem: Arginine and Proline Metabolism R_PROAKGOX1r equation: [r] : akg + o2 + pro-L --> 4hpro-LT + co2 + succ
is: ENSCAFG00000000824.2
product: 776588
fast: false
reactant: 776551
is: ENSCAFG00000005859.2
is: ENSCAFG00000014573.2
type: Reaction
reactant: 776575
is: http://identifiers.org/ec-code/1.14.11.2
name: L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) (ER)
reversible: false
product: 776612
reactant: 776563
product: 776600

828628
stoichiometry: 1.0
species: 733419
type: SpeciesReference

853759
stoichiometry: 1.0
species: 746194
type: SpeciesReference

038112
is: http://identifiers.org/ec-code/2.4.1.41
is: ENSCAFG00000006281.2
reactant: 826579
reversible: false
product: 826627
reactant: 826591
is: ENSCAFG00000007803.2
is: ENSCAFG00000007840.2
name: GalNAc transferase, Golgi apparatus
type: Reaction
product: 826615
is: ENSCAFG00000004932.2
is: ENSCAFG00000005328.2
is: ENSCAFG00000011188.2
product: 826603
is: ENSCAFG00000006614.2
is: ENSCAFG00000017644.2
is: ENSCAFG00000007798.2
notes: R_GALNTg subsystem: O-Glycan Biosynthesis R_GALNTg equation: [g] : Ser/Thr + udpacgal --> Tn_antigen + h + udp
is: ENSCAFG00000002494.2
fast: false
is: ENSCAFG00000017888.2
is: ENSCAFG00000005887.2
is: ENSCAFG00000009254.2
is: ENSCAFG00000007758.2
is: ENSCAFG00000009140.2
is: ENSCAFG00000015310.2

779121
stoichiometry: 1.0
species: 743072
type: SpeciesReference

855689
stoichiometry: 1.0
species: 741259
type: SpeciesReference

731465
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: beta-Alanine_C3H7NO2
type: Species

838676
stoichiometry: 1.0
species: 741042
type: SpeciesReference

037218
fast: false
reactant: 815945
product: 815981
type: Reaction
is: http://identifiers.org/ec-code/2.3.2.2
reactant: 815957
is: ENSCAFG00000023186.1
product: 815969
reversible: true
notes: R_GGT5r subsystem: Eicosanoid Metabolism R_GGT5r equation: [r] : h2o + leuktrC4 <==> glu-L + leuktrD4
name: Gamma-glutamyltransferase 5

790750
stoichiometry: 1.0
species: 741259
type: SpeciesReference

801819
stoichiometry: 1.0
species: 731864
type: SpeciesReference

838789
stoichiometry: 1.0
species: 735252
type: SpeciesReference

811542
stoichiometry: 5.0
species: 752483
type: SpeciesReference

033596
product: 782523
is: http://identifiers.org/ec-code/6.3.5.3
is: ENSCAFG00000017893.2
reactant: 782511
reactant: 782499
product: 782607
reversible: false
product: 782559
product: 782595
reactant: 782475
fast: false
notes: R_S3T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T3g equation: [g] : hs_pre15 + paps --> h + hspg + pap R_PRFGS subsystem: IMP Biosynthesis R_PRFGS equation: [c] : atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi
reactant: 782487
is: http://identifiers.org/ec-code/2.8.2.23
product: 782547
product: 782583
type: Reaction
product: 782535
product: 782571
reactant: 782463
reactant: 782451

730307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: N-Acetyl-D-galactosamine_C8H15NO6
type: Species

800111
stoichiometry: 1.0
species: 732441
type: SpeciesReference

813470
stoichiometry: 1.0
species: 741259
type: SpeciesReference

763731
stoichiometry: 1.0
species: 745976
type: SpeciesReference

749948
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin D2_C20H31O5
type: Species

809725
stoichiometry: 2.0
species: 746978
type: SpeciesReference

767051
stoichiometry: 1.0
species: 736656
type: SpeciesReference

736825
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol diphosphate, human uterine homolog_C1025H1670O70P20
type: Species

848775
stoichiometry: 1.0
species: 734804
type: SpeciesReference

805654
stoichiometry: 1.0
species: 727082
type: SpeciesReference

826197
stoichiometry: 1.0
species: 748567
type: SpeciesReference

733419
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Cholate_C24H39O5
type: Species

775787
stoichiometry: 2.0
species: 746918
type: SpeciesReference

741283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: H+_H
type: Species

847390
stoichiometry: 1.0
species: 751410
type: SpeciesReference

744048
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 6_C107H174N7O80SX
type: Species

730717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)3 (Glc)1 (GlcNAc)1 (Cer)1_C55H95N3O30FULLRCO
type: Species

773355
stoichiometry: 1.0
species: 737151
type: SpeciesReference

792981
stoichiometry: 1.0
species: 733678
type: SpeciesReference

765331
stoichiometry: 4.0
species: 741259
type: SpeciesReference

851978
stoichiometry: 6.0
species: 746918
type: SpeciesReference

731042
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: ADPribose_C15H21N5O14P2
type: Species

846876
stoichiometry: 1.0
species: 743396
type: SpeciesReference

784226
stoichiometry: 1.0
species: 744598
type: SpeciesReference

798716
stoichiometry: 6.0
species: 735709
type: SpeciesReference

039839
reversible: true
is: ENSCAFG00000012992.2
fast: false
is: http://identifiers.org/ec-code/1.3.99.1
is: ENSCAFG00000010951.2
name: succinate dehydrogenase
notes: R_SUCD1m subsystem: Citric Acid Cycle R_SUCD1m equation: [m] : fad + succ <==> fadh2 + fum
reactant: 841485
type: Reaction
product: 841509
is: ENSCAFG00000024546.1
product: 841521
reactant: 841497
is: ENSCAFG00000015832.2

774954
stoichiometry: 1.0
species: 729138
type: SpeciesReference

749358
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: (R)-Pantothenate_C9H16NO5
type: Species

736207
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
type: Species

808193
stoichiometry: 3.0
species: 741259
type: SpeciesReference

820655
stoichiometry: 1.0
species: 734405
type: SpeciesReference

844519
stoichiometry: 1.0
species: 739559
type: SpeciesReference

734393
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: L-Carnitine_C7H15NO3
type: Species

747890
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO
type: Species

792835
stoichiometry: 1.0
species: 745471
type: SpeciesReference

838361
stoichiometry: 3.0
species: 747148
type: SpeciesReference

812842
stoichiometry: 1.0
species: 732032
type: SpeciesReference

826808
stoichiometry: 1.0
species: 745868
type: SpeciesReference

798438
stoichiometry: 1.0
species: 747650
type: SpeciesReference

834301
stoichiometry: 1.0
species: 728692
type: SpeciesReference

771878
stoichiometry: 1.0
species: 732332
type: SpeciesReference

773691
stoichiometry: 1.0
species: 739999
type: SpeciesReference

767642
stoichiometry: 1.0
species: 747062
type: SpeciesReference

781626
stoichiometry: 1.0
species: 749466
type: SpeciesReference

801903
stoichiometry: 1.0
species: 737774
type: SpeciesReference

826906
stoichiometry: 1.0
species: 740325
type: SpeciesReference

827449
stoichiometry: 1.0
species: 746509
type: SpeciesReference

829434
stoichiometry: 1.0
species: 741151
type: SpeciesReference

041178
is: http://identifiers.org/ec-code/4.3.2.1
fast: false
notes: R_ARGSL subsystem: Alanine and Aspartate Metabolism R_ARGSL equation: [c] : argsuc <==> arg-L + fum
is: ENSCAFG00000006948.2
reactant: 855267
product: 855291
type: Reaction
name: argininosuccinate lyase
product: 855279
reversible: true

852929
stoichiometry: 3.0
species: 746400
type: SpeciesReference

776140
stoichiometry: 1.0
species: 734791
type: SpeciesReference

805369
stoichiometry: 1.0
species: 752605
type: SpeciesReference

790907
stoichiometry: 2.0
species: 741271
type: SpeciesReference

039188
reversible: false
type: Reaction
is: ENSCAFG00000006412.2
notes: R_HISD subsystem: Histidine Metabolism R_HISD equation: [c] : his-L --> nh4 + urcan
name: histidase
product: 836074
reactant: 836050
is: http://identifiers.org/ec-code/4.3.1.3
fast: false
product: 836062

749466
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Diphosphate_HO7P2
type: Species

774846
stoichiometry: 1.0
species: 732441
type: SpeciesReference

800339
stoichiometry: 2.0
species: 733981
type: SpeciesReference

726271
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25
type: Species

038196
is: ENSCAFG00000019864.1
product: 827113
product: 827088
reversible: false
reactant: 827076
name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
fast: false
reactant: 827064
type: Reaction
product: 827100
is: ENSCAFG00000024143.1
notes: R_GBGT1 subsystem: Sphingolipid Metabolism R_GBGT1 equation: [g] : gbside_hs + udpacgal --> acgagbside_hs + h + udp

742928
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Inosine_C10H12N4O5
type: Species

781565
stoichiometry: 1.0
species: 738918
type: SpeciesReference

761877
stoichiometry: 1.0
species: 733786
type: SpeciesReference

807086
stoichiometry: 1.0
species: 742843
type: SpeciesReference

729331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Cystine_C6H12N2O4S2
type: Species

032234
fast: false
product: 771154
name: sulfate transport via bicarbonate countertransport
product: 771142
type: Reaction
reversible: false
is: ENSCAFG00000005654.2
reactant: 771118
notes: R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c]
reactant: 771130

743336
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 26_C110H179N7O93S4
type: Species

850033
stoichiometry: 1.0
species: 727094
type: SpeciesReference

732841
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Biotin_C10H15N2O3S
type: Species

810700
stoichiometry: 2.0
species: 747294
type: SpeciesReference

757916
stoichiometry: 3.0
species: 732465
type: SpeciesReference

728920
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

815811
stoichiometry: 1.0
species: 748860
type: SpeciesReference

819402
stoichiometry: 1.0
species: 727444
type: SpeciesReference

798162
stoichiometry: 1.0
species: 736608
type: SpeciesReference

756432
stoichiometry: 2.0
species: 741332
type: SpeciesReference

030933
fast: false
reactant: 758811
reactant: 758799
product: 758907
type: Reaction
reactant: 758787
product: 758895
product: 758883
reactant: 758835
reactant: 758823
notes: R_TRIODTHYt subsystem: Transport, Extracellular R_TRIODTHYt equation: hco3[c] + triodthy[e] <==> hco3[e] + triodthy[c] R_THYOXt subsystem: Transport, Extracellular R_THYOXt equation: hco3[c] + thyox-L[e] <==> hco3[e] + thyox-L[c] R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_TCHOLAt subsystem: Transport, Extracellular R_TCHOLAt equation: hco3[c] + tchola[e] <==> hco3[e] + tchola[c] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c] R_ESTRADIOLGLCt subsystem: Transport, Extracellular R_ESTRADIOLGLCt equation: estradiolglc[e] + hco3[c] <==> estradiolglc[c] + hco3[e]
reactant: 758847
product: 758919
product: 758871
is: ENSCAFG00000012710.2
reactant: 758775
product: 758859
product: 758931
is: ENSCAFG00000024024.1
reversible: true

741959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: heptadecanoyl carnitine_C24H47NO4
type: Species

735300
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Cytidine_C9H13N3O5
type: Species

768574
stoichiometry: 1.0
species: 731188
type: SpeciesReference

743975
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 34_C241H385N17O202S10X
type: Species

838577
stoichiometry: 1.0
species: 751118
type: SpeciesReference

808349
stoichiometry: 2.0
species: 730124
type: SpeciesReference

751336
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Sphingosine_C18H38NO2
type: Species

736983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Dopamine_C8H12NO2
type: Species

794756
stoichiometry: 1.0
species: 741006
type: SpeciesReference

767498
stoichiometry: 2.0
species: 741332
type: SpeciesReference

834000
stoichiometry: 1.0
species: 747099
type: SpeciesReference

752740
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Reduced thioredoxin_XH2
type: Species

828086
stoichiometry: 1.0
species: 749863
type: SpeciesReference

766534
stoichiometry: 4.0
species: 741259
type: SpeciesReference

762687
stoichiometry: 1.0
species: 752496
type: SpeciesReference

730958
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: ADP_C10H12N5O10P2
type: Species

765179
stoichiometry: 1.0
species: 749200
type: SpeciesReference

843250
stoichiometry: 10.0
species: 746918
type: SpeciesReference

775077
stoichiometry: 1.0
species: 728920
type: SpeciesReference

727130
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxyphenylacetate_C8H7O4
type: Species

837700
stoichiometry: 1.0
species: 742892
type: SpeciesReference

788324
stoichiometry: 1.0
species: 738027
type: SpeciesReference

766810
stoichiometry: 2.0
species: 741259
type: SpeciesReference

036543
is: ENSCAFG00000013155.2
type: Reaction
notes: R_UDPG4E subsystem: Galactose metabolism R_UDPG4E equation: [c] : udpg <==> udpgal R_UAG4E subsystem: Aminosugar Metabolism R_UAG4E equation: [c] : uacgam <==> udpacgal
is: http://identifiers.org/ec-code/5.1.3.7
product: 809891
reversible: true
is: http://identifiers.org/ec-code/5.1.3.2
reactant: 809879
fast: false
reactant: 809866
product: 809903

788481
stoichiometry: 1.0
species: 735877
type: SpeciesReference

727540
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methoxy-4-hydroxyphenylglycolaldehyde_C9H10O4
type: Species

820824
stoichiometry: 1.0
species: 733189
type: SpeciesReference

813132
stoichiometry: 1.0
species: 738834
type: SpeciesReference

824905
stoichiometry: 1.0
species: 741536
type: SpeciesReference

806749
stoichiometry: 1.0
species: 741259
type: SpeciesReference

734902
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 1_C45H65N2O52S5
type: Species

839125
stoichiometry: 3.0
species: 746930
type: SpeciesReference

815521
stoichiometry: 1.0
species: 754027
type: SpeciesReference

855255
stoichiometry: 2.0
species: 741259
type: SpeciesReference

846306
stoichiometry: 1.0
species: 750610
type: SpeciesReference

757687
stoichiometry: 1.0
species: 727979
type: SpeciesReference

827257
stoichiometry: 2.0
species: 741187
type: SpeciesReference

814408
stoichiometry: 2.0
species: 741259
type: SpeciesReference

758218
stoichiometry: 3.0
species: 733884
type: SpeciesReference

760054
stoichiometry: 1.0
species: 746413
type: SpeciesReference

806965
stoichiometry: 2.0
species: 747074
type: SpeciesReference

739717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
type: Species

036809
reactant: 811866
notes: R_AMETt2m subsystem: Transport, Mitochondrial R_AMETt2m equation: ahcys[m] + amet[c] <==> ahcys[c] + amet[m]
product: 811890
product: 811902
reactant: 811878
name: S-Adenosyl-L-methionine reversible transport, mitochondrial
is: ENSCAFG00000006689.2
reversible: true
fast: false
type: Reaction

854159
stoichiometry: 1.0
species: 748898
type: SpeciesReference

745170
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Linoleyl carnitine_C25H45NO4
type: Species

838897
stoichiometry: 1.0
species: 742516
type: SpeciesReference

844241
stoichiometry: 1.0
species: 726428
type: SpeciesReference

764903
stoichiometry: 1.0
species: 732537
type: SpeciesReference

836653
stoichiometry: 1.0
species: 744241
type: SpeciesReference

852160
stoichiometry: 7.0
species: 741151
type: SpeciesReference

800690
stoichiometry: 1.0
species: 726742
type: SpeciesReference

035311
type: Reaction
is: ENSCAFG00000000249.1
is: ENSCAFG00000016574.2
is: ENSCAFG00000013718.2
reactant: 799485
name: phosphatidylinositol 4-phosphate 5-kinase
reactant: 799497
reversible: false
is: ENSCAFG00000004186.2
product: 799509
is: ENSCAFG00000013684.2
product: 799533
notes: R_PI4P5K subsystem: Glycerophospholipid Metabolism R_PI4P5K equation: [c] : atp + pail4p_hs --> adp + h + pail45p_hs
is: http://identifiers.org/ec-code/2.7.1.68
product: 799521
fast: false

752938
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Thiosulfate_O3S2
type: Species

739619
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO
type: Species

825302
stoichiometry: 1.0
species: 748591
type: SpeciesReference

839727
stoichiometry: 2.0
species: 745784
type: SpeciesReference

798006
stoichiometry: 1.0
species: 733786
type: SpeciesReference

032979
fast: false
product: 777616
reactant: 777591
notes: R_TREH subsystem: Starch and Sucrose Metabolism R_TREH equation: [c] : h2o + tre --> (2) glc-D
type: Reaction
reactant: 777603
name: alpha,alpha-trehalase
is: ENSCAFG00000006474.2
reversible: false
is: http://identifiers.org/ec-code/3.2.1.28

834871
stoichiometry: 1.0
species: 744676
type: SpeciesReference

037363
product: 817547
is: http://identifiers.org/ec-code/2.4.1.148
reactant: 817523
is: http://identifiers.org/ec-code/2.4.1.102
is: ENSCAFG00000016661.1
product: 817559
type: Reaction
reactant: 817511
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE4GTg subsystem: O-Glycan Biosynthesis R_CORE4GTg equation: [g] : core3 + uacgam --> core4 + h + udp
product: 817571
fast: false
product: 817535
reversible: false
reactant: 817499

734211
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Cortisone_C21H28O5
type: Species

777288
stoichiometry: 1.0
species: 727323
type: SpeciesReference

728293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-4'-Phosphopantothenate_C9H15NO8P
type: Species

782378
stoichiometry: 1.0
species: 739987
type: SpeciesReference

796671
stoichiometry: 1.0
species: 751482
type: SpeciesReference

729895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis)_XOH
type: Species

769409
stoichiometry: 1.0
species: 731936
type: SpeciesReference

802133
stoichiometry: 2.0
species: 739111
type: SpeciesReference

844313
stoichiometry: 1.0
species: 730076
type: SpeciesReference

835821
stoichiometry: 1.0
species: 739159
type: SpeciesReference

811324
stoichiometry: 5.0
species: 739926
type: SpeciesReference

853302
stoichiometry: 1.0
species: 732780
type: SpeciesReference

841353
stoichiometry: 1.0
species: 741259
type: SpeciesReference

040007
product: 842362
reactant: 842350
notes: R_ACONTm subsystem: Citric Acid Cycle R_ACONTm equation: [m] : cit <==> icit
is: ENSCAFG00000001075.2
is: http://identifiers.org/ec-code/4.2.1.3
fast: false
reversible: true
name: Aconitate hydratase
type: Reaction

751771
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2
type: Species

775210
stoichiometry: 1.0
species: 726162
type: SpeciesReference

035167
product: 796902
fast: false
product: 796914
reversible: false
reactant: 796878
notes: R_ARGSS subsystem: Alanine and Aspartate Metabolism R_ARGSS equation: [c] : asp-L + atp + citr-L --> amp + argsuc + h + ppi
is: http://identifiers.org/ec-code/6.3.4.5
reactant: 796854
type: Reaction
name: argininosuccinate synthase
is: ENSCAFG00000019897.2
reactant: 796866
is: ENSCAFG00000019896.2
product: 796890
product: 796926

731682
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Aminomuconate 6-semialdehyde_C6H7NO3
type: Species

824228
stoichiometry: 4.0
species: 753338
type: SpeciesReference

792402
stoichiometry: 1.0
species: 746978
type: SpeciesReference

773135
stoichiometry: 1.0
species: 732465
type: SpeciesReference

727347
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

750962
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Selenate_O4Se
type: Species

824373
stoichiometry: 1.0
species: 742431
type: SpeciesReference

850731
stoichiometry: 1.0
species: 730196
type: SpeciesReference

832869
stoichiometry: 1.0
species: 745591
type: SpeciesReference

763415
stoichiometry: 2.0
species: 747173
type: SpeciesReference

742357
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 14_C79H115N5O95S10X
type: Species

816161
stoichiometry: 1.0
species: 749043
type: SpeciesReference

828784
stoichiometry: 9.0
species: 741428
type: SpeciesReference

758919
stoichiometry: 1.0
species: 751844
type: SpeciesReference

814869
stoichiometry: 1.0
species: 749200
type: SpeciesReference

797493
stoichiometry: 1.0
species: 749442
type: SpeciesReference

741127
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Hydrogen peroxide_H2O2
type: Species

769932
stoichiometry: 1.0
species: 746978
type: SpeciesReference

786172
stoichiometry: 1.0
species: 749875
type: SpeciesReference

817306
stoichiometry: 1.0
species: 752265
type: SpeciesReference

726912
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Hydroxybutyrate_C4H7O3
type: Species

842013
stoichiometry: 2.0
species: 731405
type: SpeciesReference

031162
type: Reaction
reactant: 760932
reactant: 760944
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs
product: 760993
reactant: 760908
product: 760956
product: 760980
fast: false
is: ENSCAFG00000016795.2
reactant: 760920
product: 760968
reversible: false

841064
stoichiometry: 1.0
species: 732441
type: SpeciesReference

786497
stoichiometry: 1.0
species: 733335
type: SpeciesReference

731261
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8
type: Species

734755
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate C (GalNAc6S-GlcA), precursor 3_C45H67N2O42S2X
type: Species

754391
stoichiometry: 1.0
species: 754245
type: SpeciesReference

740457
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: ganglioside GM1 (homo sapiens)_C55H95N3O30FULLRCO
type: Species

747331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Ammonium_H4N
type: Species

831017
stoichiometry: 1.0
species: 728173
type: SpeciesReference

799533
stoichiometry: 1.0
species: 741259
type: SpeciesReference

850454
stoichiometry: 5.0
species: 741151
type: SpeciesReference

815232
stoichiometry: 1.0
species: 753579
type: SpeciesReference

784647
stoichiometry: 1.0
species: 749562
type: SpeciesReference

817946
stoichiometry: 1.0
species: 727118
type: SpeciesReference

836774
stoichiometry: 2.0
species: 746930
type: SpeciesReference

787772
stoichiometry: 1.0
species: 737846
type: SpeciesReference

733153
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Carbamoyl phosphate_CH2NO5P
type: Species

745435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: L-Lysine_C6H15N2O2
type: Species

770546
stoichiometry: 1.0
species: 747062
type: SpeciesReference

743552
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 4_C222H355N15O197S12
type: Species

792763
stoichiometry: 5.0
species: 748886
type: SpeciesReference

833615
stoichiometry: 3.0
species: 749200
type: SpeciesReference

776722
stoichiometry: 1.0
species: 747319
type: SpeciesReference

843950
stoichiometry: 1.0
species: 744423
type: SpeciesReference

846658
stoichiometry: 1.0
species: 738183
type: SpeciesReference

039995
is: ENSCAFG00000007417.2
fast: false
reversible: false
product: 842326
type: Reaction
reactant: 842302
is: http://identifiers.org/ec-code/3.2.1.114
notes: R_M1316Mg subsystem: N-Glycan Biosynthesis R_M1316Mg equation: [g] : (2) h2o + nm4masn --> (2) man + nm2masn
product: 842338
is: ENSCAFG00000012259.2
name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
reactant: 842314

830193
stoichiometry: 1.0
species: 734573
type: SpeciesReference

033378
reactant: 780952
is: http://identifiers.org/ec-code/1.5.1.20
reactant: 780940
product: 780976
fast: false
is: ENSCAFG00000016558.2
name: _5,10-methylenetetrahydrofolatereductase (NADPH)
product: 780964
reversible: false
notes: R_MTHFR3 subsystem: Folate Metabolism R_MTHFR3 equation: [c] : (2) h + mlthf + nadph --> 5mthf + nadp
reactant: 780928
type: Reaction

783415
stoichiometry: 1.0
species: 748687
type: SpeciesReference

749502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Diphosphate_HO7P2
type: Species

832136
stoichiometry: 1.0
species: 747698
type: SpeciesReference

813252
stoichiometry: 1.0
species: 753338
type: SpeciesReference

743408
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 31_C90H148N6O72S2
type: Species

761078
stoichiometry: 2.0
species: 730874
type: SpeciesReference

841641
stoichiometry: 2.0
species: 741151
type: SpeciesReference

794537
stoichiometry: 2.0
species: 747221
type: SpeciesReference

830313
stoichiometry: 1.0
species: 734951
type: SpeciesReference

748278
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Oxalate_C2O4
type: Species

031005
reversible: false
reactant: 759690
reactant: 759702
fast: false
product: 759787
reactant: 759714
is: ENSCAFG00000024513.1
is: http://identifiers.org/ec-code/2.7.1.137
is: ENSCAFG00000009661.2
product: 759799
type: Reaction
reactant: 759630
product: 759824
product: 759836
product: 759811
reactant: 759642
notes: R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs R_PIK3er subsystem: Inositol Phosphate Metabolism R_PIK3er equation: [r] : atp + pail_hs --> adp + h + pail3p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3Ker subsystem: Inositol Phosphate Metabolism R_PI5P3Ker equation: [r] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3Ker subsystem: Inositol Phosphate Metabolism R_PI4P3Ker equation: [r] : atp + pail4p_hs --> adp + h + pail34p_hs
product: 759763
reactant: 759654
product: 759726
product: 759751
product: 759739
reactant: 759678
reactant: 759666
product: 759775

757139
stoichiometry: 1.0
species: 732937
type: SpeciesReference

764046
stoichiometry: 1.0
species: 730693
type: SpeciesReference

792619
stoichiometry: 1.0
species: 741308
type: SpeciesReference

773015
stoichiometry: 1.0
species: 739135
type: SpeciesReference

794682
stoichiometry: 1.0
species: 741741
type: SpeciesReference

759366
stoichiometry: 1.0
species: 749200
type: SpeciesReference

040899
reversible: false
type: Reaction
product: 853145
product: 853133
notes: R_SARDHm subsystem: Urea cycle/amino group metabolism R_SARDHm equation: [m] : fad + sarcs + thf --> fadh2 + gly + mlthf
is: ENSCAFG00000019794.2
product: 853157
is: http://identifiers.org/ec-code/1.5.99.1
reactant: 853097
name: Sarcosine dehydrogenase (m)
reactant: 853109
reactant: 853121
fast: false

740180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Glycine_C2H5NO2
type: Species

851261
stoichiometry: 2.0
species: 741223
type: SpeciesReference

852640
stoichiometry: 1.0
species: 740120
type: SpeciesReference

843684
stoichiometry: 1.0
species: 734175
type: SpeciesReference

037786
reactant: 822598
product: 822683
product: 822647
fast: false
notes: R_H6MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_L equation: [r] : (0.1) dolmanp_L + m2emgacpail_hs --> (0.1) dolp_L + h + m3emgacpail_hs R_H8MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_L equation: [r] : (0.1) dolmanp_L + gpi_hs --> (0.1) dolp_L + h + m(em)3gacpail_hs R_H6MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_U equation: [r] : (0.1) dolmanp_U + m2emgacpail_hs --> (0.1) dolp_U + h + m3emgacpail_hs R_H7MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_U equation: [r] : (0.1) dolmanp_U + em2emgacpail_hs --> (0.1) dolp_U + h + mem2emgacpail_hs R_H7MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_L equation: [r] : (0.1) dolmanp_L + em2emgacpail_hs --> (0.1) dolp_L + h + mem2emgacpail_hs R_H8MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_U equation: [r] : (0.1) dolmanp_U + gpi_hs --> (0.1) dolp_U + h + m(em)3gacpail_hs
is: ENSCAFG00000013105.2
reactant: 822635
reactant: 822586
reversible: false
product: 822707
product: 822695
reactant: 822610
product: 822671
product: 822659
reactant: 822622
type: Reaction

800980
stoichiometry: 1.0
species: 736777
type: SpeciesReference

835689
stoichiometry: 1.0
species: 739220
type: SpeciesReference

816330
stoichiometry: 1.0
species: 733896
type: SpeciesReference

738762
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO
type: Species

785789
stoichiometry: 2.0
species: 738087
type: SpeciesReference

778650
stoichiometry: 1.0
species: 731417
type: SpeciesReference

751118
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: L-Serine_C3H7NO3
type: Species

847170
stoichiometry: 1.0
species: 744736
type: SpeciesReference

817186
stoichiometry: 1.0
species: 754183
type: SpeciesReference

754245
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Xylulose 1-phosphate_C5H9O8P
type: Species

040224
reversible: false
is: ENSCAFG00000005468.2
product: 845135
name: phosphofructokinase
notes: R_PFK subsystem: Glycolysis/Gluconeogenesis R_PFK equation: [c] : atp + f6p --> adp + fdp + h
fast: false
type: Reaction
product: 845111
is: ENSCAFG00000010846.2
product: 845123
reactant: 845087
is: http://identifiers.org/ec-code/2.7.1.11
is: ENSCAFG00000009035.2
reactant: 845099

781782
stoichiometry: 1.0
species: 741259
type: SpeciesReference

726053
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

752521
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Thymine_C5H6N2O2
type: Species

778191
stoichiometry: 1.0
species: 735865
type: SpeciesReference

776891
stoichiometry: 1.0
species: 726392
type: SpeciesReference

743757
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 18_C163H262N11O132S5X
type: Species

764190
stoichiometry: 1.0
species: 729810
type: SpeciesReference

754862
stoichiometry: 1.0
species: 740349
type: SpeciesReference

811024
stoichiometry: 4.0
species: 741259
type: SpeciesReference

825748
stoichiometry: 1.0
species: 753882
type: SpeciesReference

853422
stoichiometry: 1.0
species: 732780
type: SpeciesReference

770938
stoichiometry: 1.0
species: 749851
type: SpeciesReference

846718
stoichiometry: 1.0
species: 742007
type: SpeciesReference

807676
stoichiometry: 1.0
species: 741308
type: SpeciesReference

781408
stoichiometry: 1.0
species: 739027
type: SpeciesReference

785464
stoichiometry: 1.0
species: 741464
type: SpeciesReference

769578
stoichiometry: 1.0
species: 742345
type: SpeciesReference

831570
stoichiometry: 1.0
species: 738979
type: SpeciesReference

756164
stoichiometry: 1.0
species: 753145
type: SpeciesReference

774628
stoichiometry: 1.0
species: 739522
type: SpeciesReference

797614
stoichiometry: 1.0
species: 732477
type: SpeciesReference

765976
stoichiometry: 1.0
species: 745242
type: SpeciesReference

830837
stoichiometry: 1.0
species: 741332
type: SpeciesReference

732404
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Aspartate_C4H6NO4
type: Species

737043
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Dephospho-CoA_C21H33N7O13P2S
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dCTP_C9H12N3O13P3
type: Species

808734
stoichiometry: 1.0
species: 748567
type: SpeciesReference

780049
stoichiometry: 1.0
species: 732768
type: SpeciesReference

768005
stoichiometry: 1.0
species: 727034
type: SpeciesReference

855461
stoichiometry: 3.0
species: 741344
type: SpeciesReference

797506
stoichiometry: 1.0
species: 742612
type: SpeciesReference

804066
stoichiometry: 1.0
species: 740349
type: SpeciesReference

854086
stoichiometry: 1.0
species: 730500
type: SpeciesReference

830945
stoichiometry: 1.0
species: 741078
type: SpeciesReference

758448
stoichiometry: 1.0
species: 754305
type: SpeciesReference

782715
stoichiometry: 1.0
species: 738894
type: SpeciesReference

801711
stoichiometry: 1.0
species: 745423
type: SpeciesReference

759075
stoichiometry: 2.0
species: 737460
type: SpeciesReference

776879
stoichiometry: 1.0
species: 747698
type: SpeciesReference

740566
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: GMP_C10H12N5O8P
type: Species

840255
stoichiometry: 1.0
species: 737139
type: SpeciesReference

761186
stoichiometry: 2.0
species: 735276
type: SpeciesReference

749249
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Phosphate_HO4P
type: Species

039695
name: D-sorbitol dehydrogenase (D-fructose producing)
reversible: false
fast: false
notes: R_SBTD_D2 subsystem: Fructose and Mannose Metabolism R_SBTD_D2 equation: [c] : nad + sbt-D --> fru + h + nadh
is: http://identifiers.org/ec-code/1.1.1.14
product: 840135
is: ENSCAFG00000013672.2
reactant: 840099
product: 840123
type: Reaction
product: 840111
reactant: 840087

832244
stoichiometry: 1.0
species: 733981
type: SpeciesReference

738558
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Fucose_C6H12O5
type: Species

813362
stoichiometry: 3.0
species: 731405
type: SpeciesReference

775366
stoichiometry: 1.0
species: 728932
type: SpeciesReference

843842
stoichiometry: 1.0
species: 744241
type: SpeciesReference

800762
stoichiometry: 1.0
species: 738171
type: SpeciesReference

794055
stoichiometry: 1.0
species: 741151
type: SpeciesReference

853530
stoichiometry: 1.0
species: 739729
type: SpeciesReference

734646
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: chondroitin sulfate B (IdoA2S-GalNAc4s), precursor 5_C45H66N2O45S3X
type: Species

775631
stoichiometry: 1.0
species: 730946
type: SpeciesReference

793150
stoichiometry: 2.0
species: 745663
type: SpeciesReference

790318
stoichiometry: 1.0
species: 735397
type: SpeciesReference

032547
product: 774132
notes: R_GF6PTA subsystem: Aminosugar Metabolism R_GF6PTA equation: [c] : f6p + gln-L --> gam6p + glu-L
reversible: false
fast: false
product: 774145
is: http://identifiers.org/ec-code/2.6.1.16
name: glutamine-fructose-6-phosphate transaminase
reactant: 774106
reactant: 774119
type: Reaction
is: ENSCAFG00000000433.2
is: ENSCAFG00000003296.2

748121
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: octadecenoyl carnitine_C25H47NO4
type: Species

829181
stoichiometry: 1.0
species: 730922
type: SpeciesReference

737943
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Ethanol_C2H6O
type: Species

855315
stoichiometry: 1.0
species: 729392
type: SpeciesReference

761585
stoichiometry: 6.0
species: 748886
type: SpeciesReference

744724
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Lanosterol_C30H50O
type: Species

741404
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: hyaluronan biosynthesis, precursor 1_C14H20NO11
type: Species

808794
stoichiometry: 5.0
species: 730922
type: SpeciesReference

786280
stoichiometry: 2.0
species: 741139
type: SpeciesReference

777975
stoichiometry: 1.0
species: 738690
type: SpeciesReference

765440
stoichiometry: 2.0
species: 733009
type: SpeciesReference

805141
stoichiometry: 1.0
species: 745182
type: SpeciesReference

843576
stoichiometry: 1.0
species: 747842
type: SpeciesReference

791871
stoichiometry: 1.0
species: 736303
type: SpeciesReference

835533
stoichiometry: 1.0
species: 744459
type: SpeciesReference

852796
stoichiometry: 1.0
species: 739852
type: SpeciesReference

764263
stoichiometry: 1.0
species: 747099
type: SpeciesReference

833506
stoichiometry: 1.0
species: 733226
type: SpeciesReference

843092
stoichiometry: 1.0
species: 731561
type: SpeciesReference

732780
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Biotinyl-5'-AMP_C20H27N7O9PS
type: Species

744169
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 7_C44H73N4O30X
type: Species

032691
name: Fe(III) reduction (ascorbate)
reactant: 775474
fast: false
product: 775486
notes: R_FE3R2e subsystem: Heme Biosynthesis R_FE3R2e equation: [e] : ascb-L + (2) fe3 --> dhdascb + (2) fe2 + (2) h
product: 775498
reactant: 775462
reversible: false
is: ENSCAFG00000012667.2
type: Reaction
product: 775510

733262
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: CDPethanolamine_C11H19N4O11P2
type: Species

834156
stoichiometry: 1.0
species: 732537
type: SpeciesReference

770655
stoichiometry: 1.0
species: 734381
type: SpeciesReference

828339
stoichiometry: 1.0
species: 741283
type: SpeciesReference

749658
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: glycophosphatidylinositol (GPI)-anchored protein precursor_XY
type: Species

756272
stoichiometry: 1.0
species: 747099
type: SpeciesReference

808626
stoichiometry: 1.0
species: 739438
type: SpeciesReference

841797
stoichiometry: 1.0
species: 749490
type: SpeciesReference

031595
reactant: 764588
product: 764625
is: ENSCAFG00000011027.2
fast: false
is: http://identifiers.org/ec-code/4.1.1.17
name: Ornithine Decarboxylase
type: Reaction
reactant: 764600
is: ENSCAFG00000003415.2
notes: R_ORNDC subsystem: Urea cycle/amino group metabolism R_ORNDC equation: [c] : h + orn --> co2 + ptrc
reversible: false
product: 764613

807784
stoichiometry: 1.0
species: 731273
type: SpeciesReference

827894
stoichiometry: 1.0
species: 733871
type: SpeciesReference

750818
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Sedoheptulose 7-phosphate_C7H13O10P
type: Species

783971
stoichiometry: 1.0
species: 744700
type: SpeciesReference

746219
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Metanephrine_C10H16NO3
type: Species

771505
stoichiometry: 1.0
species: 733945
type: SpeciesReference

842578
stoichiometry: 1.0
species: 749743
type: SpeciesReference

817838
stoichiometry: 1.0
species: 737290
type: SpeciesReference

787880
stoichiometry: 1.0
species: 753750
type: SpeciesReference

758508
stoichiometry: 1.0
species: 751747
type: SpeciesReference

784539
stoichiometry: 10.0
species: 730922
type: SpeciesReference

849683
stoichiometry: 1.0
species: 734853
type: SpeciesReference

779471
stoichiometry: 1.0
species: 728015
type: SpeciesReference

033027
product: 778155
product: 778179
reactant: 778143
is: ENSCAFG00000018692.2
product: 778167
reactant: 778119
notes: R_CITt4_2 subsystem: Transport, Extracellular R_CITt4_2 equation: cit[e] + (2) na1[e] <==> cit[c] + (2) na1[c] R_SUCCt4_2 subsystem: Transport, Extracellular R_SUCCt4_2 equation: (2) na1[e] + succ[e] <==> (2) na1[c] + succ[c]
reversible: true
type: Reaction
reactant: 778131
fast: false

803907
stoichiometry: 1.0
species: 749562
type: SpeciesReference

037677
reactant: 821691
reactant: 821715
product: 821751
is: ENSCAFG00000002130.2
reversible: true
type: Reaction
reactant: 821703
notes: R_NAt5 subsystem: Transport, Extracellular R_NAt5 equation: na1[c] + nh4[e] <==> na1[e] + nh4[c] R_NAt3_1 subsystem: Transport, Extracellular R_NAt3_1 equation: h[e] + na1[c] <==> h[c] + na1[e]
is: ENSCAFG00000012207.2
fast: false
product: 821739
is: ENSCAFG00000010902.2
product: 821727

765217
stoichiometry: 1.0
species: 741259
type: SpeciesReference

814516
stoichiometry: 6.0
species: 747173
type: SpeciesReference

788060
stoichiometry: 1.0
species: 741440
type: SpeciesReference

036434
is: ENSCAFG00000009546.1
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_INSTt4 subsystem: Transport, Extracellular R_INSTt4 equation: inost[e] + na1[e] <==> inost[c] + na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
product: 809072
is: ENSCAFG00000018237.2
product: 809096
reactant: 809047
fast: false
is: ENSCAFG00000013498.2
reversible: true
product: 809084
reactant: 809034
type: Reaction
reactant: 809060

783304
stoichiometry: 1.0
species: 751711
type: SpeciesReference

818353
stoichiometry: 4.0
species: 749418
type: SpeciesReference

753157
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: UDP_C9H11N2O12P2
type: Species

833062
stoichiometry: 1.0
species: 745711
type: SpeciesReference

809422
stoichiometry: 1.0
species: 730922
type: SpeciesReference

754971
stoichiometry: 1.0
species: 744637
type: SpeciesReference

752630
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: timnodonic acid C20:5, n-3_C20H29O2
type: Species

841929
stoichiometry: 1.0
species: 731549
type: SpeciesReference

820932
stoichiometry: 1.0
species: 735155
type: SpeciesReference

743648
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I_C247H393N17O213S12X
type: Species

759474
stoichiometry: 1.0
species: 727819
type: SpeciesReference

745687
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: (alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1660H2728N20O520P20
type: Species

035925
product: 803919
reactant: 803882
type: Reaction
product: 803944
is: ENSCAFG00000012145.2
product: 803956
product: 803932
reactant: 803907
fast: false
reactant: 803894
notes: R_PMI1346PHn subsystem: Inositol Phosphate Metabolism R_PMI1346PHn equation: [n] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI12346PHn subsystem: Inositol Phosphate Metabolism R_PMI12346PHn equation: [n] : h2o + ppmi12346p --> h + minohp + pi
is: http://identifiers.org/ec-code/3.6.1.52
reversible: false

753906
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: _24-Hydroxycholesterol_C27H46O2
type: Species

039092
product: 834349
product: 834325
is: http://identifiers.org/ec-code/1.2.1.21
product: 834253
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
product: 834337
reactant: 834132
product: 834313
product: 834241
reversible: false
reactant: 834084
product: 834301
product: 834361
fast: false
product: 834289
reactant: 834096
reactant: 834192
reactant: 834204
reactant: 834168
product: 834373
reactant: 834108
is: http://identifiers.org/ec-code/1.2.1.3
product: 834229
reactant: 834072
reactant: 834144
type: Reaction
product: 834277
reactant: 834180
reactant: 834156
product: 834265
is: ENSCAFG00000001791.2
reactant: 834216
reactant: 834120

812409
stoichiometry: 1.0
species: 730076
type: SpeciesReference

769686
stoichiometry: 1.0
species: 735059
type: SpeciesReference

848005
stoichiometry: 1.0
species: 732116
type: SpeciesReference

813023
stoichiometry: 2.0
species: 727082
type: SpeciesReference

785043
stoichiometry: 2.0
species: 754039
type: SpeciesReference

035852
product: 803375
fast: false
reactant: 803351
type: Reaction
reactant: 803339
reactant: 803326
reactant: 803363
is: ENSCAFG00000013015.2
is: ENSCAFG00000011504.2
notes: R_SRTN23OX subsystem: Tryptophan metabolism R_SRTN23OX equation: [c] : o2 + srtn --> f5hoxkyn R_MELATN23DOX subsystem: Tryptophan metabolism R_MELATN23DOX equation: [c] : melatn + o2 --> fna5moxam R_5HTRPDOX subsystem: Tryptophan metabolism R_5HTRPDOX equation: [c] : 5htrp + o2 --> 5hoxnfkyn
product: 803399
reversible: false
is: http://identifiers.org/ec-code/1.13.11.42
product: 803387

799810
stoichiometry: 1.0
species: 745423
type: SpeciesReference

847068
stoichiometry: 1.0
species: 744386
type: SpeciesReference

034324
reversible: true
reactant: 788902
product: 789119
is: ENSCAFG00000004339.2
product: 789071
fast: false
product: 789022
product: 789095
reactant: 788998
is: ENSCAFG00000019677.2
type: Reaction
product: 789034
product: 789107
product: 789143
product: 789131
is: ENSCAFG00000023628.1
reactant: 789010
reactant: 788986
is: http://identifiers.org/ec-code/2.7.4.6
product: 789083
reactant: 788938
reactant: 788914
reactant: 788974
reactant: 788950
notes: R_NDPK7m subsystem: Nucleotides R_NDPK7m equation: [m] : atp + dcdp <==> adp + dctp R_NDPK8m subsystem: Nucleotides R_NDPK8m equation: [m] : atp + dadp <==> adp + datp R_NDPK6m subsystem: Nucleotides R_NDPK6m equation: [m] : atp + dudp <==> adp + dutp R_NDPK4m subsystem: Nucleotides R_NDPK4m equation: [m] : atp + dtdp <==> adp + dttp R_NDPK2m subsystem: Nucleotides R_NDPK2m equation: [m] : atp + udp <==> adp + utp R_NDPK10m subsystem: Nucleotides R_NDPK10m equation: [m] : atp + didp <==> adp + ditp R_NDPK3m subsystem: Nucleotides R_NDPK3m equation: [m] : atp + cdp <==> adp + ctp R_NDPK5m subsystem: Nucleotides R_NDPK5m equation: [m] : atp + dgdp <==> adp + dgtp R_NDPK1m subsystem: Nucleotides R_NDPK1m equation: [m] : atp + gdp <==> adp + gtp R_NDPK9m subsystem: Nucleotides R_NDPK9m equation: [m] : atp + idp <==> adp + itp
reactant: 788890
reactant: 788926
reactant: 788962
product: 789058
product: 789046

778904
stoichiometry: 1.0
species: 728655
type: SpeciesReference

747050
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2
type: Species

756860
stoichiometry: 8.0
species: 741283
type: SpeciesReference

845559
stoichiometry: 2.0
species: 730922
type: SpeciesReference

846924
stoichiometry: 1.0
species: 743156
type: SpeciesReference

727697
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _3-Oxododecanoyl-CoA_C33H52N7O18P3S
type: Species

822863
stoichiometry: 1.0
species: 737508
type: SpeciesReference

040332
product: 845559
reversible: true
reactant: 845535
is: ENSCAFG00000020105.2
fast: false
reactant: 845547
is: ENSCAFG00000017744.2
is: http://identifiers.org/ec-code/2.7.4.3
name: adenylate kinase
notes: R_ADK1 subsystem: Nucleotides R_ADK1 equation: [c] : amp + atp <==> (2) adp
type: Reaction

824578
stoichiometry: 1.0
species: 751917
type: SpeciesReference

772605
stoichiometry: 1.0
species: 750177
type: SpeciesReference

843141
stoichiometry: 1.0
species: 749887
type: SpeciesReference

038306
name: phosphomannomutase
product: 828014
type: Reaction
reversible: true
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p
fast: false
is: http://identifiers.org/ec-code/5.4.2.8
is: ENSCAFG00000019010.1
reactant: 828002
is: ENSCAFG00000001049.2

735889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: all trans Decaprenyl diphosphate_C50H81O7P2
type: Species

777397
stoichiometry: 1.0
species: 730221
type: SpeciesReference

034975
notes: R_HMGCOARr subsystem: Cholesterol Metabolism R_HMGCOARr equation: [r] : (2) h + hmgcoa + (2) nadph --> coa + mev-R + (2) nadp R_HMGCOARx subsystem: Cholesterol Metabolism R_HMGCOARx equation: [x] : (2) h + hmgcoa + (2) nadph --> coa + mev-R + (2) nadp
is: http://identifiers.org/ec-code/1.1.1.34
fast: false
product: 794586
reactant: 794501
product: 794622
is: ENSCAFG00000009517.2
type: Reaction
reactant: 794513
reactant: 794550
product: 794598
product: 794610
reactant: 794562
reactant: 794525
product: 794634
reversible: false
product: 794574
reactant: 794537

757066
stoichiometry: 1.0
species: 751989
type: SpeciesReference

838205
stoichiometry: 1.0
species: 726864
type: SpeciesReference

798860
stoichiometry: 7.0
species: 736073
type: SpeciesReference

815921
stoichiometry: 4.0
species: 741259
type: SpeciesReference

792342
stoichiometry: 1.0
species: 747148
type: SpeciesReference

839618
stoichiometry: 1.0
species: 745603
type: SpeciesReference

035203
product: 797445
reactant: 797145
reactant: 797084
reactant: 797193
product: 797289
product: 797373
reactant: 797096
is: ENSCAFG00000020075.2
product: 797397
product: 797301
product: 797409
product: 797325
fast: false
product: 797277
reactant: 797241
reactant: 797253
product: 797337
reactant: 797265
is: ENSCAFG00000020184.2
type: Reaction
product: 797433
reactant: 797205
reactant: 797217
reactant: 797120
reactant: 797181
product: 797457
is: ENSCAFG00000008005.2
reactant: 797229
reactant: 797132
product: 797313
reversible: false
product: 797385
reactant: 797157
notes: R_S6T5g subsystem: Keratan sulfate biosynthesis R_S6T5g equation: [g] : ksi_pre7 + paps --> h + ksi_pre8 + pap R_S6T6g subsystem: Keratan sulfate biosynthesis R_S6T6g equation: [g] : ksi_pre10 + paps --> h + ksi_pre11 + pap R_S6T7g subsystem: Keratan sulfate biosynthesis R_S6T7g equation: [g] : ksi_pre13 + paps --> h + ksi_pre14 + pap R_S6T13g subsystem: Keratan sulfate biosynthesis R_S6T13g equation: [g] : ksi_pre31 + paps --> h + ksi_pre32 + pap R_S6T8g subsystem: Keratan sulfate biosynthesis R_S6T8g equation: [g] : ksi_pre16 + paps --> h + ksi_pre17 + pap R_S6T17g subsystem: Keratan sulfate biosynthesis R_S6T17g equation: [g] : ksii_core4_pre8 + paps --> h + ksii_core4_pre9 + pap R_S6T1g subsystem: Keratan sulfate biosynthesis R_S6T1g equation: [g] : ksii_core2_pre5 + paps --> h + ksii_core2_pre6 + pap R_S6T14g subsystem: Keratan sulfate biosynthesis R_S6T14g equation: [g] : ksi_pre34 + paps --> h + ksi_pre35 + pap R_S6T10g subsystem: Keratan sulfate biosynthesis R_S6T10g equation: [g] : ksi_pre22 + paps --> h + ksi_pre23 + pap R_S6T9g subsystem: Keratan sulfate biosynthesis R_S6T9g equation: [g] : ksi_pre19 + paps --> h + ksi_pre20 + pap R_S6T12g subsystem: Keratan sulfate biosynthesis R_S6T12g equation: [g] : ksi_pre28 + paps --> h + ksi_pre29 + pap R_S6T11g subsystem: Keratan sulfate biosynthesis R_S6T11g equation: [g] : ksi_pre25 + paps --> h + ksi_pre26 + pap R_S6T2g subsystem: Keratan sulfate biosynthesis R_S6T2g equation: [g] : ksii_core2_pre8 + paps --> h + ksii_core2_pre9 + pap R_S6T4g subsystem: Keratan sulfate biosynthesis R_S6T4g equation: [g] : ksi_pre4 + paps --> h + ksi_pre5 + pap R_S6T16g subsystem: Keratan sulfate biosynthesis R_S6T16g equation: [g] : ksii_core4_pre5 + paps --> h + ksii_core4_pre6 + pap
reactant: 797169
product: 797469
reactant: 797108
product: 797361
product: 797421
product: 797349

816765
stoichiometry: 2.0
species: 735769
type: SpeciesReference

840111
stoichiometry: 1.0
species: 738474
type: SpeciesReference

757795
stoichiometry: 1.0
species: 750914
type: SpeciesReference

755755
stoichiometry: 1.0
species: 741971
type: SpeciesReference

765864
stoichiometry: 1.0
species: 751615
type: SpeciesReference

852051
stoichiometry: 1.0
species: 749200
type: SpeciesReference

743132
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 11_C180H289N12O158S9
type: Species

771239
stoichiometry: 2.0
species: 741078
type: SpeciesReference

825952
stoichiometry: 2.0
species: 731755
type: SpeciesReference

762579
stoichiometry: 1.0
species: 730922
type: SpeciesReference

836544
stoichiometry: 1.0
species: 744784
type: SpeciesReference

849103
stoichiometry: 1.0
species: 743348
type: SpeciesReference

834763
stoichiometry: 1.0
species: 744676
type: SpeciesReference

806533
stoichiometry: 2.0
species: 741259
type: SpeciesReference

812094
stoichiometry: 2.0
species: 747209
type: SpeciesReference

736559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: dITP_C10H11N4O13P3
type: Species

748423
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2
type: Species

786064
stoichiometry: 1.0
species: 751082
type: SpeciesReference

848667
stoichiometry: 1.0
species: 734841
type: SpeciesReference

789107
stoichiometry: 1.0
species: 743036
type: SpeciesReference

809827
stoichiometry: 1.0
species: 729429
type: SpeciesReference

735168
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: CTP_C9H12N3O14P3
type: Species

780109
stoichiometry: 1.0
species: 732756
type: SpeciesReference

037943
product: 824312
is: ENSCAFG00000024345.1
reactant: 824216
is: ENSCAFG00000009477.2
reactant: 824192
reversible: false
notes: R_GLCAT9g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT9g equation: [g] : hs_pre7 + udpglcur --> h + hs_pre8 + udp R_GLCAT6g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT6g equation: [g] : hs_pre1 + udpglcur --> h + hs_pre2 + udp R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCAT8g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT8g equation: [g] : hs_pre5 + udpglcur --> h + hs_pre6 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCAT7g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT7g equation: [g] : hs_pre3 + udpglcur --> h + hs_pre4 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp
reactant: 824240
type: Reaction
reactant: 824204
product: 824397
product: 824385
reactant: 824228
product: 824348
product: 824360
fast: false
product: 824409
product: 824324
reactant: 824288
product: 824373
product: 824336
reactant: 824276
product: 824421
is: ENSCAFG00000000831.2
reactant: 824300
reactant: 824264
reactant: 824252

752854
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Tryptamine_C10H13N2
type: Species

816053
stoichiometry: 2.0
species: 747294
type: SpeciesReference

814759
stoichiometry: 1.0
species: 737907
type: SpeciesReference

769518
stoichiometry: 1.0
species: 734054
type: SpeciesReference

802024
stoichiometry: 3.0
species: 741416
type: SpeciesReference

845111
stoichiometry: 1.0
species: 738171
type: SpeciesReference

850887
stoichiometry: 1.0
species: 737618
type: SpeciesReference

763305
stoichiometry: 2.0
species: 741308
type: SpeciesReference

745543
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C46H77N2O35X
type: Species

851104
stoichiometry: 1.0
species: 747062
type: SpeciesReference

796562
stoichiometry: 1.0
species: 745158
type: SpeciesReference

761719
stoichiometry: 1.0
species: 745832
type: SpeciesReference

804923
stoichiometry: 1.0
species: 747662
type: SpeciesReference

728860
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

732020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _20alpha-Hydroxyprogesterone_C21H32O2
type: Species

849260
stoichiometry: 1.0
species: 741404
type: SpeciesReference

794476
stoichiometry: 1.0
species: 751094
type: SpeciesReference

825676
stoichiometry: 1.0
species: 742552
type: SpeciesReference

038453
reversible: false
notes: R_MI4PP subsystem: Inositol Phosphate Metabolism R_MI4PP equation: [c] : h2o + mi4p-D --> inost + pi R_MI3PP subsystem: Inositol Phosphate Metabolism R_MI3PP equation: [c] : h2o + mi3p-D --> inost + pi R_MI1PP subsystem: Inositol Phosphate Metabolism R_MI1PP equation: [c] : h2o + mi1p-D --> inost + pi
fast: false
reactant: 829313
reactant: 829277
reactant: 829289
is: http://identifiers.org/ec-code/3.1.3.25
product: 829337
reactant: 829301
product: 829325
is: ENSCAFG00000018807.2
type: Reaction

035059
type: Reaction
reactant: 795298
fast: false
reactant: 795310
reversible: false
is: http://identifiers.org/ec-code/1.2.4.1
is: ENSCAFG00000007340.2
is: ENSCAFG00000013030.2
product: 795334
is: ENSCAFG00000014016.2
product: 795322
notes: R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh
name: pyruvate dehydrogenase
reactant: 795286
product: 795346

750056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Prostaglandin F2alpha_C20H33O5
type: Species

809290
stoichiometry: 3.0
species: 741296
type: SpeciesReference

037086
product: 814396
reactant: 814348
reactant: 814336
product: 814372
fast: false
is: ENSCAFG00000002236.2
reactant: 814324
product: 814408
product: 814384
is: http://identifiers.org/ec-code/6.3.2.6
reactant: 814312
type: Reaction
product: 814360
reversible: true
is: http://identifiers.org/ec-code/4.1.1.21
reactant: 814299
notes: R_AIRCr subsystem: IMP Biosynthesis R_AIRCr equation: [c] : air + co2 <==> 5aizc + h R_PRASCS subsystem: IMP Biosynthesis R_PRASCS equation: [c] : 5aizc + asp-L + atp <==> 25aics + adp + h + pi

845039
stoichiometry: 1.0
species: 728209
type: SpeciesReference

846414
stoichiometry: 1.0
species: 730124
type: SpeciesReference

773244
stoichiometry: 1.0
species: 737338
type: SpeciesReference

844023
stoichiometry: 1.0
species: 744435
type: SpeciesReference

742200
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 2_C79H116N5O96S10
type: Species

842724
stoichiometry: 1.0
species: 726560
type: SpeciesReference

792559
stoichiometry: 1.0
species: 741199
type: SpeciesReference

747782
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Superoxide anion_O2
type: Species

774265
stoichiometry: 1.0
species: 747746
type: SpeciesReference

795850
stoichiometry: 1.0
species: 743721
type: SpeciesReference

791245
stoichiometry: 35.0
species: 747038
type: SpeciesReference

740775
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Guanosine_C10H13N5O5
type: Species

828953
stoichiometry: 1.0
species: 732429
type: SpeciesReference

779267
stoichiometry: 1.0
species: 747746
type: SpeciesReference

034553
is: http://identifiers.org/ec-code/2.7.7.41
reactant: 790979
is: ENSCAFG00000006020.2
notes: R_CDSm subsystem: Glycerophospholipid Metabolism R_CDSm equation: [m] : ctp + h + pa_hs --> cdpdag_hs + ppi
product: 791003
fast: false
reversible: false
name: phosphatidate cytidylyltransferase
product: 790991
type: Reaction
reactant: 790967
reactant: 790955

777531
stoichiometry: 5.0
species: 741259
type: SpeciesReference

844639
stoichiometry: 1.0
species: 732817
type: SpeciesReference

032703
product: 775559
type: Reaction
name: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
product: 775571
reactant: 775535
reactant: 775522
product: 775547
is: ENSCAFG00000012938.1
fast: false
is: http://identifiers.org/ec-code/2.4.1.101
notes: R_M13N2Tg subsystem: N-Glycan Biosynthesis R_M13N2Tg equation: [g] : m4masn + uacgam --> h + nm4masn + udp
reversible: false

848402
stoichiometry: 23.0
species: 741139
type: SpeciesReference

755056
stoichiometry: 1.0
species: 742043
type: SpeciesReference

733690
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Citrate_C6H5O7
type: Species

793714
stoichiometry: 1.0
species: 730124
type: SpeciesReference

794223
stoichiometry: 1.0
species: 735047
type: SpeciesReference

747625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: nervonyl coenzyme A_C45H76N7O17P3S
type: Species

834421
stoichiometry: 1.0
species: 735276
type: SpeciesReference

765632
stoichiometry: 1.0
species: 732587
type: SpeciesReference

811662
stoichiometry: 1.0
species: 730922
type: SpeciesReference

805562
stoichiometry: 2.0
species: 730076
type: SpeciesReference

030525
type: Reaction
name: Hydroxymethylglutaryl CoA synthase (ir)
reactant: 755417
notes: R_HMGCOASi subsystem: Cholesterol Metabolism R_HMGCOASi equation: [c] : aacoa + accoa + h2o --> coa + h + hmgcoa
is: ENSCAFG00000018572.2
reactant: 755405
reactant: 755393
fast: false
reversible: false
product: 755441
product: 755453
product: 755429
is: http://identifiers.org/ec-code/4.1.3.5

778494
stoichiometry: 1.0
species: 750261
type: SpeciesReference

769119
stoichiometry: 1.0
species: 748254
type: SpeciesReference

812938
stoichiometry: 1.0
species: 727540
type: SpeciesReference

853614
stoichiometry: 1.0
species: 739414
type: SpeciesReference

810062
stoichiometry: 1.0
species: 741428
type: SpeciesReference

776478
stoichiometry: 1.0
species: 733141
type: SpeciesReference

740059
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: gamma-L-Glutamyl-L-cysteine_C8H13N2O5S
type: Species

729786
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: protein-linked serine or threonine residue (O-glycosylation site)_XH
type: Species

751699
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Sucrose_C12H22O11
type: Species

773499
stoichiometry: 1.0
species: 740180
type: SpeciesReference

822273
stoichiometry: 1.0
species: 739365
type: SpeciesReference

802530
stoichiometry: 1.0
species: 735793
type: SpeciesReference

764492
stoichiometry: 1.0
species: 738015
type: SpeciesReference

771311
stoichiometry: 1.0
species: 732465
type: SpeciesReference

823081
stoichiometry: 1.0
species: 738918
type: SpeciesReference

809866
stoichiometry: 1.0
species: 753266
type: SpeciesReference

788637
stoichiometry: 1.0
species: 741777
type: SpeciesReference

789421
stoichiometry: 1.0
species: 733069
type: SpeciesReference

785900
stoichiometry: 1.0
species: 744796
type: SpeciesReference

780470
stoichiometry: 35.0
species: 747038
type: SpeciesReference

798462
stoichiometry: 1.0
species: 751603
type: SpeciesReference

819112
stoichiometry: 1.0
species: 741139
type: SpeciesReference

762349
stoichiometry: 1.0
species: 733642
type: SpeciesReference

781993
stoichiometry: 1.0
species: 742479
type: SpeciesReference

789867
stoichiometry: 1.0
species: 741223
type: SpeciesReference

744193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate II (core 2-linked), degradation product 9_C30H50N3O20X
type: Species

766412
stoichiometry: 1.0
species: 729549
type: SpeciesReference

745146
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: linoleic coenzyme A_C39H62N7O17P3S
type: Species

764806
stoichiometry: 1.0
species: 742660
type: SpeciesReference

746521
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _1D-myo-Inositol 1-phosphate_C6H11O9P
type: Species

771421
stoichiometry: 1.0
species: 741308
type: SpeciesReference

040585
is: ENSCAFG00000006243.2
is: http://identifiers.org/ec-code/3.5.99.6
reactant: 849803
notes: R_G6PDA subsystem: Aminosugar Metabolism R_G6PDA equation: [c] : gam6p + h2o --> f6p + nh4
reversible: false
product: 849815
fast: false
is: ENSCAFG00000001871.2
type: Reaction
product: 849828
reactant: 849791
name: glucosamine-6-phosphate deaminase

787988
stoichiometry: 1.0
species: 738918
type: SpeciesReference

833796
stoichiometry: 1.0
species: 744784
type: SpeciesReference

774106
stoichiometry: 1.0
species: 739926
type: SpeciesReference

807243
stoichiometry: 1.0
species: 746882
type: SpeciesReference

814967
stoichiometry: 2.0
species: 734127
type: SpeciesReference

038622
type: Reaction
reactant: 830409
is: ENSCAFG00000015312.2
is: http://identifiers.org/ec-code/3.2.1.14
reversible: false
is: ENSCAFG00000013313.2
product: 830421
notes: R_CHTNASE subsystem: Aminosugar Metabolism R_CHTNASE equation: [c] : chtn + (2) h2o --> (3) acgam
fast: false
reactant: 830397
name: chitinase

036833
product: 812070
is: ENSCAFG00000010063.2
product: 812058
is: http://identifiers.org/ec-code/1.1.1.95
is: ENSCAFG00000023328.1
is: ENSCAFG00000025283.1
notes: R_PGCD subsystem: Glycine, Serine, and Threonine Metabolism R_PGCD equation: [c] : 3pg + nad --> 3php + h + nadh
is: ENSCAFG00000025426.1
is: ENSCAFG00000010843.2
reactant: 812034
type: Reaction
product: 812082
fast: false
reactant: 812046
reversible: false
name: phosphoglycerate dehydrogenase

786810
stoichiometry: 1.0
species: 751470
type: SpeciesReference

830621
stoichiometry: 3.0
species: 741259
type: SpeciesReference

766714
stoichiometry: 1.0
species: 746978
type: SpeciesReference

750285
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Pyridoxamine 5'-phosphate_C8H12N2O5P
type: Species

819666
stoichiometry: 1.0
species: 743336
type: SpeciesReference

840653
stoichiometry: 1.0
species: 749442
type: SpeciesReference

795814
stoichiometry: 1.0
species: 744084
type: SpeciesReference

845367
stoichiometry: 1.0
species: 741090
type: SpeciesReference

835015
stoichiometry: 1.0
species: 753350
type: SpeciesReference

753688
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: vaccenic acid_C18H33O2
type: Species

845692
stoichiometry: 1.0
species: 728908
type: SpeciesReference

854593
stoichiometry: 3.0
species: 751082
type: SpeciesReference

811120
stoichiometry: 1.0
species: 753157
type: SpeciesReference

727118
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3,4-Dihydroxyphenylacetaldehyde_C8H8O3
type: Species

842182
stoichiometry: 1.0
species: 753133
type: SpeciesReference

852808
stoichiometry: 1.0
species: 734283
type: SpeciesReference

849526
stoichiometry: 1.0
species: 734561
type: SpeciesReference

849912
stoichiometry: 1.0
species: 727540
type: SpeciesReference

809254
stoichiometry: 1.0
species: 730645
type: SpeciesReference

743853
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 25_C199H319N14O163S7X
type: Species

838457
stoichiometry: 1.0
species: 736111
type: SpeciesReference

738450
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Farnesyl diphosphate_C15H25O7P2
type: Species

774725
stoichiometry: 1.0
species: 753290
type: SpeciesReference

854291
stoichiometry: 1.0
species: 726632
type: SpeciesReference

726392
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _12-Hydroperoxyeicosa-5,8,10,14-tetraenoate_C20H31O4
type: Species

820533
stoichiometry: 1.0
species: 746726
type: SpeciesReference

781420
stoichiometry: 1.0
species: 738015
type: SpeciesReference

770377
stoichiometry: 1.0
species: 742345
type: SpeciesReference

794780
stoichiometry: 1.0
species: 731333
type: SpeciesReference

851533
stoichiometry: 1.0
species: 729368
type: SpeciesReference

784671
stoichiometry: 1.0
species: 746581
type: SpeciesReference

761732
stoichiometry: 1.0
species: 737618
type: SpeciesReference

729210
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: acyl carrier protein_C11H21N2O7PRS
type: Species

821366
stoichiometry: 1.0
species: 752569
type: SpeciesReference

783135
stoichiometry: 1.0
species: 750369
type: SpeciesReference

751360
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

817730
stoichiometry: 1.0
species: 746327
type: SpeciesReference

812613
stoichiometry: 9.0
species: 746918
type: SpeciesReference

783280
stoichiometry: 1.0
species: 744712
type: SpeciesReference

771758
stoichiometry: 1.0
species: 740180
type: SpeciesReference

829578
stoichiometry: 1.0
species: 736099
type: SpeciesReference

848970
stoichiometry: 1.0
species: 743612
type: SpeciesReference

780145
stoichiometry: 1.0
species: 732829
type: SpeciesReference

743793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: keratan sulfate I biosynthesis, precursor 20_C171H274N12O140S6X
type: Species

748847
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2
type: Species

735445
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2
type: Species

786028
stoichiometry: 1.0
species: 749043
type: SpeciesReference

778095
stoichiometry: 1.0
species: 753206
type: SpeciesReference

823298
stoichiometry: 7.0
species: 733909
type: SpeciesReference

730524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
type: Species

781847
stoichiometry: 1.0
species: 741259
type: SpeciesReference

742782
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Isoleucine_C6H13NO2
type: Species

743216
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 18_C146H235N10O127S7
type: Species

760783
stoichiometry: 4.0
species: 741223
type: SpeciesReference

732985
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

034890
fast: false
product: 793894
is: http://identifiers.org/ec-code/5.4.2.7
notes: R_PPM subsystem: Pentose Phosphate Pathway R_PPM equation: [c] : r1p <==> r5p R_PGMT subsystem: Glycolysis/Gluconeogenesis R_PGMT equation: [c] : g1p <==> g6p
is: ENSCAFG00000018670.2
type: Reaction
reactant: 793858
reactant: 793870
is: http://identifiers.org/ec-code/5.4.2.2
product: 793882
reversible: true

810844
stoichiometry: 2.0
species: 747123
type: SpeciesReference

819522
stoichiometry: 1.0
species: 744181
type: SpeciesReference

757941
stoichiometry: 2.0
species: 743012
type: SpeciesReference

855569
stoichiometry: 2.0
species: 741151
type: SpeciesReference

749972
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Prostaglandin D2_C20H31O5
type: Species

771541
stoichiometry: 1.0
species: 750128
type: SpeciesReference

813591
stoichiometry: 5.0
species: 741283
type: SpeciesReference

751214
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Sulfate_O4S
type: Species

736704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

805775
stoichiometry: 25.0
species: 741259
type: SpeciesReference

838241
stoichiometry: 1.0
species: 741308
type: SpeciesReference

826832
stoichiometry: 1.0
species: 751771
type: SpeciesReference

813446
stoichiometry: 1.0
species: 727881
type: SpeciesReference

812722
stoichiometry: 1.0
species: 752854
type: SpeciesReference

036107
is: http://identifiers.org/ec-code/3.1.4.17
product: 806713
reactant: 806629
is: http://identifiers.org/ec-code/6.4.1.3
product: 806749
reversible: false
fast: false
is: ENSCAFG00000007170.2
reactant: 806677
product: 806701
product: 806725
reactant: 806665
reactant: 806641
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PPCOACm subsystem: Valine, Leucine, and Isoleucine Metabolism R_PPCOACm equation: [m] : atp + hco3 + ppcoa --> adp + h + mmcoa-S + pi
product: 806689
reactant: 806653
product: 806737
type: Reaction

728728
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Hydroxy-L-tryptophan_C11H12N2O3
type: Species

745001
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: lignoceryl carnitine_C31H61NO4
type: Species

033173
product: 778976
is: ENSCAFG00000005354.2
type: Reaction
reactant: 778940
product: 778964
fast: false
name: Ferrochelatase, mitochondrial
reactant: 778952
notes: R_FCLTm subsystem: Heme Biosynthesis R_FCLTm equation: [m] : fe2 + ppp9 --> (2) h + pheme
reversible: false
is: http://identifiers.org/ec-code/4.99.1.1

791497
stoichiometry: 23.0
species: 741139
type: SpeciesReference

765035
stoichiometry: 25.0
species: 741259
type: SpeciesReference

767762
stoichiometry: 6.0
species: 732441
type: SpeciesReference

758630
stoichiometry: 2.0
species: 731803
type: SpeciesReference

833651
stoichiometry: 3.0
species: 727991
type: SpeciesReference

796537
stoichiometry: 1.0
species: 750213
type: SpeciesReference

840520
stoichiometry: 2.0
species: 732925
type: SpeciesReference

783788
stoichiometry: 1.0
species: 751699
type: SpeciesReference

818146
stoichiometry: 1.0
species: 744598
type: SpeciesReference

838133
stoichiometry: 1.0
species: 747698
type: SpeciesReference

850490
stoichiometry: 1.0
species: 736511
type: SpeciesReference

804296
stoichiometry: 1.0
species: 748898
type: SpeciesReference

800255
stoichiometry: 2.0
species: 741308
type: SpeciesReference

732659
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Bilirubin monoglucuronide_C39H44N4O12
type: Species

768174
stoichiometry: 6.0
species: 734005
type: SpeciesReference

805249
stoichiometry: 1.0
species: 750141
type: SpeciesReference

797361
stoichiometry: 1.0
species: 744302
type: SpeciesReference

754692
stoichiometry: 1.0
species: 744700
type: SpeciesReference

774652
stoichiometry: 1.0
species: 733419
type: SpeciesReference

824035
stoichiometry: 1.0
species: 741151
type: SpeciesReference

734791
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 3_C37H54NO41S3
type: Species

809146
stoichiometry: 1.0
species: 742369
type: SpeciesReference

792306
stoichiometry: 1.0
species: 731852
type: SpeciesReference

731164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Adrenaline_C9H14NO3
type: Species

729635
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: R total 3 carnitine_CO2FULLR3C7H14NO2
type: Species

772171
stoichiometry: 1.0
species: 743721
type: SpeciesReference

848041
stoichiometry: 1.0
species: 752253
type: SpeciesReference

822598
stoichiometry: 2.0
species: 740651
type: SpeciesReference

846730
stoichiometry: 1.0
species: 744374
type: SpeciesReference

800556
stoichiometry: 1.0
species: 736922
type: SpeciesReference

763876
stoichiometry: 2.0
species: 733884
type: SpeciesReference

803544
stoichiometry: 6.0
species: 746978
type: SpeciesReference

802700
stoichiometry: 1.0
species: 743240
type: SpeciesReference

036277
fast: false
is: ENSCAFG00000001376.2
product: 808073
product: 808061
is: ENSCAFG00000009051.2
product: 808085
reactant: 808025
is: ENSCAFG00000010191.2
reversible: false
notes: R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e]
reactant: 808037
type: Reaction
reactant: 808049

741874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Homoserine_C4H9NO3
type: Species

743324
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 25_C118H192N8O98S4
type: Species

850021
stoichiometry: 1.0
species: 739877
type: SpeciesReference

032246
product: 771214
fast: false
reactant: 771166
is: http://identifiers.org/ec-code/1.2.3.1
is: ENSCAFG00000023664.1
product: 771239
reactant: 771190
reversible: false
reactant: 771178
type: Reaction
product: 771226
reactant: 771202
notes: R_PYDXDH subsystem: Vitamin B6 Metabolism R_PYDXDH equation: [c] : h2o + o2 + pydx --> 4pyrdx + h2o2 R_5HOXINDACTO2OX subsystem: Tryptophan metabolism R_5HOXINDACTO2OX equation: [c] : 5hoxindact + h2o + o2 --> 5hoxindoa + h + h2o2
is: ENSCAFG00000025299.1
is: ENSCAFG00000011544.2
product: 771251

845259
stoichiometry: 1.0
species: 730922
type: SpeciesReference

750926
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Se-Adenosylselenohomocysteine_C14H20N6O5Se
type: Species

728956
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _6-Hydroxymelatonin_C13H16N2O3
type: Species

770486
stoichiometry: 1.0
species: 747002
type: SpeciesReference

726283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25
type: Species

761841
stoichiometry: 1.0
species: 731102
type: SpeciesReference

807098
stoichiometry: 1.0
species: 743072
type: SpeciesReference

035191
product: 797036
product: 797060
reactant: 797012
is: ENSCAFG00000014423.2
notes: R_ST3GAL61g subsystem: Blood Group Biosynthesis R_ST3GAL61g equation: [g] : cmpacna + gal14acglcgalgluside_hs --> acngal14acglcgalgluside_hs + cmp + h R_ST3GAL62g subsystem: Blood Group Biosynthesis R_ST3GAL62g equation: [g] : cmpacna + galacglcgal14acglcgalgluside_hs --> acngalacglcgal14acglcgalgluside_hs + cmp + h
type: Reaction
reactant: 797024
is: ENSCAFG00000004982.2
product: 797048
reversible: false
fast: false
reactant: 797000
product: 797072

814540
stoichiometry: 1.0
species: 729955
type: SpeciesReference

749478
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Diphosphate_HO7P2
type: Species

785199
stoichiometry: 1.0
species: 734853
type: SpeciesReference

738341
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Formate_CH1O2
type: Species

776176
stoichiometry: 1.0
species: 742284
type: SpeciesReference

788036
stoichiometry: 1.0
species: 728185
type: SpeciesReference

800327
stoichiometry: 1.0
species: 749430
type: SpeciesReference

835809
stoichiometry: 1.0
species: 739305
type: SpeciesReference

795706
stoichiometry: 1.0
species: 739099
type: SpeciesReference

770692
stoichiometry: 1.0
species: 730777
type: SpeciesReference

827437
stoichiometry: 1.0
species: 746533
type: SpeciesReference

781638
stoichiometry: 2.0
species: 735409
type: SpeciesReference

826918
stoichiometry: 1.0
species: 729675
type: SpeciesReference

814893
stoichiometry: 1.0
species: 730922
type: SpeciesReference

852917
stoichiometry: 5.0
species: 741320
type: SpeciesReference

768587
stoichiometry: 1.0
species: 727759
type: SpeciesReference

039176
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PDE4n subsystem: Nucleotides R_PDE4n equation: [n] : 35cgmp + h2o --> gmp + h
type: Reaction
product: 836014
reactant: 835978
reversible: false
product: 836038
reactant: 835990
product: 836002
fast: false
product: 836026
reactant: 835966
is: http://identifiers.org/ec-code/3.1.4.17
is: ENSCAFG00000010487.2
reactant: 835954

805357
stoichiometry: 1.0
species: 731405
type: SpeciesReference

758520
stoichiometry: 3.0
species: 730922
type: SpeciesReference

849417
stoichiometry: 2.0
species: 734598
type: SpeciesReference

730946
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: ADP_C10H12N5O10P2
type: Species

828050
stoichiometry: 1.0
species: 748194
type: SpeciesReference

765143
stoichiometry: 1.0
species: 732441
type: SpeciesReference

034781
product: 793030
name: heparan sulfate 6-sulfotransferase, Golgi apparatus
product: 793042
reactant: 793005
fast: false
is: ENSCAFG00000018850.2
reversible: false
type: Reaction
notes: R_S6T25g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T25g equation: [g] : hs_pre12 + (3) paps --> (3) h + hs_pre13 + (3) pap
product: 793018
reactant: 792993
is: ENSCAFG00000004232.2

040790
product: 852196
is: ENSCAFG00000023676.1
is: http://identifiers.org/ec-code/3.1.3.5
reactant: 852123
reactant: 852087
reactant: 852160
reactant: 852111
product: 852244
reactant: 852172
product: 852232
product: 852268
type: Reaction
notes: R_NT5C subsystem: NAD Metabolism R_NT5C equation: [c] : h2o + nicrnt --> nicrns + pi R_NTD9 subsystem: Nucleotides R_NTD9 equation: [c] : gmp + h2o --> gsn + pi R_NTD6 subsystem: Nucleotides R_NTD6 equation: [c] : damp + h2o --> dad-2 + pi R_NTD11 subsystem: Purine Catabolism R_NTD11 equation: [c] : h2o + imp --> ins + pi R_NTD10 subsystem: Nucleotides R_NTD10 equation: [c] : h2o + xmp --> pi + xtsn R_NTD8 subsystem: Nucleotides R_NTD8 equation: [c] : dgmp + h2o --> dgsn + pi R_NTD7 subsystem: Nucleotides R_NTD7 equation: [c] : amp + h2o --> adn + pi
reactant: 852148
product: 852208
reactant: 852135
fast: false
product: 852184
reversible: false
product: 852220
is: ENSCAFG00000010354.2
product: 852256
reactant: 852099

739644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: glycochenodeoxycholate_C26H43NO5
type: Species

777818
stoichiometry: 1.0
species: 738690
type: SpeciesReference

842590
stoichiometry: 1.0
species: 749695
type: SpeciesReference

040645
type: Reaction
product: 850791
product: 850779
reactant: 850755
reactant: 850743
is: ENSCAFG00000011241.2
is: ENSCAFG00000024024.1
product: 850803
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c]
reversible: true
fast: false
reactant: 850767

780253
stoichiometry: 1.0
species: 741271
type: SpeciesReference

746243
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Mercaptopyruvate_C3H3O3S
type: Species

832881
stoichiometry: 1.0
species: 745603
type: SpeciesReference

838565
stoichiometry: 1.0
species: 740156
type: SpeciesReference

748699
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2
type: Species

735336
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxyadenosine_C10H13N5O3
type: Species

808337
stoichiometry: 1.0
species: 729355
type: SpeciesReference

815823
stoichiometry: 4.0
species: 741151
type: SpeciesReference

798150
stoichiometry: 1.0
species: 752121
type: SpeciesReference

822406
stoichiometry: 1.0
species: 727504
type: SpeciesReference

732877
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: Butyrate (n-C4:0)_C4H7O2
type: Species

030945
reactant: 758943
notes: R_MCOATAm subsystem: Fatty Acid Metabolism R_MCOATAm equation: [m] : ACP + malcoa <==> coa + malACP
type: Reaction
is: http://identifiers.org/ec-code/2.3.1.39
fast: false
reactant: 758955
product: 758979
is: ENSCAFG00000000918.2
name: Malonyl-CoA-ACP transacylase, mitochondrial
reversible: true
product: 758967

740205
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Glycine_C2H5NO2
type: Species

741947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: heptadecanoyl carnitine_C24H47NO4
type: Species

846840
stoichiometry: 1.0
species: 744121
type: SpeciesReference

784214
stoichiometry: 1.0
species: 731465
type: SpeciesReference

765343
stoichiometry: 1.0
species: 741741
type: SpeciesReference

800666
stoichiometry: 2.0
species: 746918
type: SpeciesReference

778638
stoichiometry: 1.0
species: 751639
type: SpeciesReference

803944
stoichiometry: 2.0
species: 749261
type: SpeciesReference

036990
product: 813506
is: ENSCAFG00000014961.2
product: 813494
type: Reaction
reversible: true
fast: false
name: testicular 17-beta-hydroxysteroid dehydrogenase
reactant: 813482
reactant: 813470
notes: R_HSD17B1 subsystem: Steroid Metabolism R_HSD17B1 equation: [c] : estrone + h + nadph <==> estradiol + nadp
reactant: 813458
is: http://identifiers.org/ec-code/1.1.1.62
is: ENSCAFG00000000927.2

033064
product: 778384
reactant: 778360
reactant: 778348
product: 778372
is: ENSCAFG00000013498.2
is: ENSCAFG00000010165.2
name: glucose transport via sodium symport
is: ENSCAFG00000018237.2
type: Reaction
reversible: true
fast: false
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c]

732441
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: ATP_C10H12N5O13P3
type: Species

034095
product: 786280
fast: false
notes: R_LPCOXp subsystem: Lysine Metabolism R_LPCOXp equation: [x] : Lpipecol + o2 --> h + h2o2 + thp2c R_SARCOXp subsystem: Glycine, Serine, and Threonine Metabolism R_SARCOXp equation: [x] : h2o + o2 + sarcs --> fald + gly + h2o2
is: ENSCAFG00000018883.2
is: http://identifiers.org/ec-code/1.5.3.7
reactant: 786208
product: 786256
reactant: 786244
product: 786268
reactant: 786232
reactant: 786220
type: Reaction
reversible: false
is: http://identifiers.org/ec-code/1.5.3.1
product: 786304
product: 786292

801638
stoichiometry: 1.0
species: 745399
type: SpeciesReference

732188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: C20:4-CoA_C41H62N7O17P3S
type: Species

773343
stoichiometry: 2.0
species: 730922
type: SpeciesReference

786244
stoichiometry: 1.0
species: 750890
type: SpeciesReference

726608
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: _1 acyl phosphoglycerol_C6H13O7PFULLRCO2
type: Species

731054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: ADPribose_C15H21N5O14P2
type: Species

832556
stoichiometry: 1.0
species: 733274
type: SpeciesReference

834192
stoichiometry: 12.0
species: 741151
type: SpeciesReference

809713
stoichiometry: 1.0
species: 732188
type: SpeciesReference

736813
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Dolichol diphosphate, human liver homolog_C1080H1758O70P20
type: Species

805666
stoichiometry: 1.0
species: 740349
type: SpeciesReference

767087
stoichiometry: 1.0
species: 738087
type: SpeciesReference

848763
stoichiometry: 1.0
species: 744193
type: SpeciesReference

775607
stoichiometry: 1.0
species: 732465
type: SpeciesReference

838025
stoichiometry: 1.0
species: 733347
type: SpeciesReference

031777
fast: false
is: http://identifiers.org/ec-code/1.1.1.94
name: glycerol-3-phosphate dehydrogenase (NAD)
notes: R_G3PD1 subsystem: Glycerophospholipid Metabolism R_G3PD1 equation: [c] : glyc3p + nad <==> dhap + h + nadh
type: Reaction
reactant: 766714
reversible: true
product: 766738
product: 766762
product: 766750
reactant: 766726
is: ENSCAFG00000008288.2

798042
stoichiometry: 1.0
species: 744952
type: SpeciesReference

843818
stoichiometry: 1.0
species: 743951
type: SpeciesReference

795454
stoichiometry: 1.0
species: 732308
type: SpeciesReference

771866
stoichiometry: 10.0
species: 746918
type: SpeciesReference

767654
stoichiometry: 1.0
species: 727384
type: SpeciesReference

766388
stoichiometry: 1.0
species: 729726
type: SpeciesReference

741296
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: H+_H
type: Species

749261
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Phosphate_HO4P
type: Species

746942
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: Sodium_Na
type: Species

834313
stoichiometry: 1.0
species: 744637
type: SpeciesReference

812830
stoichiometry: 12.0
species: 747698
type: SpeciesReference

781746
stoichiometry: 1.0
species: 746315
type: SpeciesReference

840291
stoichiometry: 1.0
species: 740530
type: SpeciesReference

759039
stoichiometry: 1.0
species: 736279
type: SpeciesReference

831498
stoichiometry: 4.0
species: 741283
type: SpeciesReference

732768
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Biocytin_C16H28N4O4S
type: Species

749322
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S
type: Species

854183
stoichiometry: 1.0
species: 741777
type: SpeciesReference

840411
stoichiometry: 1.0
species: 736595
type: SpeciesReference

774942
stoichiometry: 1.0
species: 746774
type: SpeciesReference

783897
stoichiometry: 1.0
species: 748411
type: SpeciesReference

736219
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
type: Species

765404
stoichiometry: 1.0
species: 741151
type: SpeciesReference

822165
stoichiometry: 1.0
species: 739232
type: SpeciesReference

802386
stoichiometry: 1.0
species: 750466
type: SpeciesReference

739087
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
type: Species

824143
stoichiometry: 1.0
species: 739123
type: SpeciesReference

034661
reversible: true
is: ENSCAFG00000019667.2
type: Reaction
is: ENSCAFG00000000212.2
reactant: 792269
name: glucose transport (uniport)
fast: false
notes: R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]
product: 792281
is: ENSCAFG00000015634.2

780687
stoichiometry: 1.0
species: 732212
type: SpeciesReference

803616
stoichiometry: 1.0
species: 747209
type: SpeciesReference

039503
product: 838613
notes: R_SPTix subsystem: Glycine, Serine, and Threonine Metabolism R_SPTix equation: [x] : pyr + ser-L --> ala-L + hpyr R_AGTix subsystem: Alanine and Aspartate Metabolism R_AGTix equation: [x] : ala-L + glx --> gly + pyr
is: http://identifiers.org/ec-code/2.6.1.44
fast: false
product: 838601
reactant: 838565
reactant: 838589
reversible: false
product: 838638
is: ENSCAFG00000012744.2
product: 838626
reactant: 838553
reactant: 838577
type: Reaction

776588
stoichiometry: 1.0
species: 728161
type: SpeciesReference

738123
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Formaldehyde_CH2O
type: Species

808025
stoichiometry: 4.0
species: 741416
type: SpeciesReference

802422
stoichiometry: 1.0
species: 749466
type: SpeciesReference

829999
stoichiometry: 2.0
species: 731549
type: SpeciesReference

779868
stoichiometry: 2.0
species: 736752
type: SpeciesReference

794115
stoichiometry: 8.0
species: 748687
type: SpeciesReference

839305
stoichiometry: 4.0
species: 741187
type: SpeciesReference

746086
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: D-Mannose_C6H12O6
type: Species

839955
stoichiometry: 1.0
species: 732176
type: SpeciesReference

779158
stoichiometry: 1.0
species: 739027
type: SpeciesReference

748735
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2
type: Species

855002
stoichiometry: 8.0
species: 741283
type: SpeciesReference

805454
stoichiometry: 2.0
species: 741151
type: SpeciesReference

798402
stoichiometry: 1.0
species: 752049
type: SpeciesReference

728836
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Oxoproline_C5H6NO3
type: Species

790762
stoichiometry: 1.0
species: 747050
type: SpeciesReference

811554
stoichiometry: 5.0
species: 739939
type: SpeciesReference

740168
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Glycine_C2H5NO2
type: Species

837279
stoichiometry: 2.0
species: 747148
type: SpeciesReference

823660
stoichiometry: 3.0
species: 735962
type: SpeciesReference

032811
is: http://identifiers.org/ec-code/2.5.1.17
modifier: 776514
modifier: 776526
product: 776478
modifier: 776502
is: ENSCAFG00000007682.2
notes: R_CBLATm subsystem: Vitamin B12 Metabolism R_CBLATm equation: [m] : atp + cbl1 + h <==> adocbl + pppi R_CBL2tm subsystem: Transport, Mitochondrial R_CBL2tm equation: cbl2[c] --> cbl2[m]
modifier: 776539
reversible: false
fast: false
reactant: 776466
type: Reaction
modifier: 776490

038124
reactant: 826651
is: http://identifiers.org/ec-code/3.2.1.49
product: 826687
reversible: false
product: 826712
reactant: 826663
product: 826699
reactant: 826675
type: Reaction
fast: false
notes: R_NAGAly subsystem: Sphingolipid Metabolism R_NAGAly equation: [l] : acgagbside_hs + h + udp --> gbside_hs + udpacgal R_NAGA2ly subsystem: Keratan sulfate degradation R_NAGA2ly equation: [l] : Tn_antigen + h + udp --> Ser/Thr + udpacgal
is: ENSCAFG00000019874.2
reactant: 826639

741548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Hexadecenoyl carnitine_C23H43NO4
type: Species

742079
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 17_C43H65N2O48S4
type: Species

855677
stoichiometry: 1.0
species: 751422
type: SpeciesReference

782919
stoichiometry: 3.0
species: 747002
type: SpeciesReference

727795
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Sulfino-L-alanine_C3H5NO4S
type: Species

845475
stoichiometry: 1.0
species: 726826
type: SpeciesReference

753471
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: UMP_C9H11N2O9P
type: Species

843116
stoichiometry: 1.0
species: 746303
type: SpeciesReference

837074
stoichiometry: 1.0
species: 749297
type: SpeciesReference

766521
stoichiometry: 1.0
species: 732404
type: SpeciesReference

834727
stoichiometry: 1.0
species: 732056
type: SpeciesReference

836447
stoichiometry: 1.0
species: 740180
type: SpeciesReference

742672
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Indole-3-acetaldehyde_C10H9NO
type: Species

801403
stoichiometry: 2.0
species: 742588
type: SpeciesReference

750393
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Pyruvate_C3H3O3
type: Species

762980
stoichiometry: 1.0
species: 731549
type: SpeciesReference

788746
stoichiometry: 2.0
species: 734091
type: SpeciesReference

835292
stoichiometry: 1.0
species: 752325
type: SpeciesReference

034216
is: http://identifiers.org/ec-code/3.6.1.21
reversible: false
reactant: 787928
reactant: 787952
type: Reaction
is: http://identifiers.org/ec-code/3.6.1.13
fast: false
product: 788000
is: ENSCAFG00000004794.2
product: 787976
reactant: 787964
product: 788012
notes: R_ADPGLC subsystem: Nucleotides R_ADPGLC equation: [c] : adpglc + h2o --> amp + g1p + (2) h R_ADPMAN subsystem: Nucleotides R_ADPMAN equation: [c] : adpman + h2o --> amp + (2) h + man1p R_ADPRDP subsystem: Nucleotides R_ADPRDP equation: [c] : adprib + h2o --> amp + (2) h + r5p
product: 787988
product: 788024
reactant: 787940

763646
stoichiometry: 2.0
species: 741259
type: SpeciesReference

796104
stoichiometry: 1.0
species: 743914
type: SpeciesReference

746677
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S
type: Species

803314
stoichiometry: 1.0
species: 741308
type: SpeciesReference

844796
stoichiometry: 1.0
species: 750369
type: SpeciesReference

729368
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Kynurenine_C10H12N2O3
type: Species

727009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _2-Oxobutanoate_C4H5O3
type: Species

845583
stoichiometry: 1.0
species: 726199
type: SpeciesReference

852244
stoichiometry: 1.0
species: 742916
type: SpeciesReference

728113
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-4-Hydroxyglutamate semialdehyde_C5H9NO4
type: Species

846960
stoichiometry: 1.0
species: 743288
type: SpeciesReference

819775
stoichiometry: 5.0
species: 730657
type: SpeciesReference

035828
reactant: 803134
product: 803182
is: http://identifiers.org/ec-code/6.3.5.2
product: 803230
reactant: 803158
notes: R_GMPS2 subsystem: Nucleotides R_GMPS2 equation: [c] : atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi
name: GMP synthase
type: Reaction
product: 803206
fast: false
reversible: false
product: 803194
product: 803218
reactant: 803170
is: ENSCAFG00000008780.2
reactant: 803146

789978
stoichiometry: 3.0
species: 741151
type: SpeciesReference

819268
stoichiometry: 1.0
species: 737399
type: SpeciesReference

768439
stoichiometry: 1.0
species: 730512
type: SpeciesReference

833350
stoichiometry: 1.0
species: 749200
type: SpeciesReference

789579
stoichiometry: 2.0
species: 730922
type: SpeciesReference

797096
stoichiometry: 1.0
species: 744522
type: SpeciesReference

747014
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

038731
product: 831258
type: Reaction
product: 831270
notes: R_SIAT9g subsystem: Sphingolipid Metabolism R_SIAT9g equation: [g] : cmpacna + galgluside_hs --> cmp + gm3_hs + h
reactant: 831234
is: http://identifiers.org/ec-code/2.4.99.9
fast: false
name: Lactosylceramide alpha-2,3-sialyltransferase, Golgi apparatus
product: 831282
is: ENSCAFG00000007653.2
reactant: 831246
reversible: false

826275
stoichiometry: 1.0
species: 748459
type: SpeciesReference

741729
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: hexacosanoyl carnitine_C33H65NO4
type: Species

738798
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)3 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1_C62H109N2O35FULLRCO
type: Species

798582
stoichiometry: 7.0
species: 737215
type: SpeciesReference

828218
stoichiometry: 1.0
species: 752508
type: SpeciesReference

769264
stoichiometry: 1.0
species: 751627
type: SpeciesReference

793594
stoichiometry: 1.0
species: 734537
type: SpeciesReference

802808
stoichiometry: 1.0
species: 727807
type: SpeciesReference

807663
stoichiometry: 2.0
species: 749249
type: SpeciesReference

788180
stoichiometry: 1.0
species: 746074
type: SpeciesReference

828808
stoichiometry: 1.0
species: 753314
type: SpeciesReference

040863
is: http://identifiers.org/ec-code/2.7.1.151
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.127
reactant: 852869
product: 852941
product: 852893
fast: false
reactant: 852881
is: http://identifiers.org/ec-code/2.7.1.140
is: ENSCAFG00000012264.2
reversible: false
product: 852929
notes: R_MI145P6Kn subsystem: Inositol Phosphate Metabolism R_MI145P6Kn equation: [n] : atp + mi145p --> adp + h + mi1456p R_MI1456PKn subsystem: Inositol Phosphate Metabolism R_MI1456PKn equation: [n] : atp + mi1456p --> adp + h + mi13456p R_MI1346PKn subsystem: Inositol Phosphate Metabolism R_MI1346PKn equation: [n] : atp + mi1346p --> adp + h + mi13456p R_MI1345PKn subsystem: Inositol Phosphate Metabolism R_MI1345PKn equation: [n] : atp + mi1345p --> adp + h + mi13456p R_MI145PKn subsystem: Inositol Phosphate Metabolism R_MI145PKn equation: [n] : atp + mi145p --> adp + h + mi1345p
product: 852917
reactant: 852845
reactant: 852833
product: 852905
reactant: 852857

830519
stoichiometry: 1.0
species: 741127
type: SpeciesReference

852652
stoichiometry: 2.0
species: 747062
type: SpeciesReference

823406
stoichiometry: 1.0
species: 740970
type: SpeciesReference

835677
stoichiometry: 1.0
species: 741175
type: SpeciesReference

847183
stoichiometry: 1.0
species: 752593
type: SpeciesReference

841809
stoichiometry: 1.0
species: 737302
type: SpeciesReference

800992
stoichiometry: 1.0
species: 746978
type: SpeciesReference

739426
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Glucosamine_C6H14NO5
type: Species

794670
stoichiometry: 2.0
species: 747698
type: SpeciesReference

776019
stoichiometry: 1.0
species: 745399
type: SpeciesReference

764058
stoichiometry: 1.0
species: 740711
type: SpeciesReference

780037
stoichiometry: 1.0
species: 741199
type: SpeciesReference

039394
type: Reaction
product: 837808
reactant: 837736
reactant: 837724
fast: false
reactant: 837748
product: 837796
product: 837772
reversible: false
is: ENSCAFG00000012085.2
reactant: 837760
product: 837820
product: 837784
notes: R_CAMPt subsystem: Transport, Extracellular R_CAMPt equation: atp[c] + camp[c] + h2o[c] --> adp[c] + camp[e] + h[c] + pi[c] R_CGMPt subsystem: Transport, Extracellular R_CGMPt equation: _35cgmp[c] + atp[c] + h2o[c] --> 35cgmp[e] + adp[c] + h[c] + pi[c]

797626
stoichiometry: 1.0
species: 748338
type: SpeciesReference

830825
stoichiometry: 1.0
species: 733395
type: SpeciesReference

737079
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Desmosterol_C27H44O
type: Species

769542
stoichiometry: 1.0
species: 731646
type: SpeciesReference

808746
stoichiometry: 1.0
species: 748411
type: SpeciesReference

787626
stoichiometry: 1.0
species: 740922
type: SpeciesReference

848149
stoichiometry: 2.0
species: 741344
type: SpeciesReference

031993
is: ENSCAFG00000003922.2
product: 768915
reactant: 768855
type: Reaction
reactant: 768879
product: 768891
reversible: true
reactant: 768843
product: 768903
notes: R_PHEtec subsystem: Transport, Extracellular R_PHEtec equation: phe-L[e] <==> phe-L[c] R_TYRt subsystem: Transport, Extracellular R_TYRt equation: tyr-L[e] <==> tyr-L[c] R_TRPt subsystem: Transport, Extracellular R_TRPt equation: trp-L[e] <==> trp-L[c] R_34DHPHEt subsystem: Transport, Extracellular R_34DHPHEt equation: _34dhphe[e] <==> 34dhphe[c]
fast: false
reactant: 768867
product: 768927

755333
stoichiometry: 1.0
species: 752752
type: SpeciesReference

036579
is: http://identifiers.org/ec-code/6.2.1.4
reactant: 810147
reactant: 810183
reactant: 810135
reactant: 810171
product: 810243
notes: R_SUCOAS1m subsystem: Citric Acid Cycle R_SUCOAS1m equation: [m] : coa + gtp + succ <==> gdp + pi + succoa R_MECOAS1m subsystem: C5-Branched dibasic acid metabolism R_MECOAS1m equation: [m] : coa + gtp + mescon <==> gdp + mescoa + pi R_ITCOAL1m subsystem: C5-Branched dibasic acid metabolism R_ITCOAL1m equation: [m] : coa + gtp + itacon <==> gdp + itaccoa + pi
product: 810207
reversible: true
type: Reaction
is: ENSCAFG00000006612.2
reactant: 810159
fast: false
product: 810195
product: 810231
product: 810219

785452
stoichiometry: 1.0
species: 741259
type: SpeciesReference

756152
stoichiometry: 1.0
species: 740542
type: SpeciesReference

740421
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: glycogen, structure 3 (glycogenin-7[1,4-Glc])_C42H71O36X
type: Species

800882
stoichiometry: 1.0
species: 738039
type: SpeciesReference

842434
stoichiometry: 1.0
species: 750562
type: SpeciesReference

754850
stoichiometry: 1.0
species: 739877
type: SpeciesReference

726065
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

771649
stoichiometry: 1.0
species: 741078
type: SpeciesReference

040212
product: 845051
is: http://identifiers.org/ec-code/2.6.1.6
reactant: 845003
is: http://identifiers.org/ec-code/2.6.1.42
is: ENSCAFG00000003901.2
reactant: 844990
product: 845039
reversible: true
product: 845063
fast: false
reactant: 845015
product: 845075
reactant: 845027
type: Reaction
notes: R_VALTAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTAm equation: [m] : akg + val-L <==> 3mob + glu-L R_ILETAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETAm equation: [m] : akg + ile-L <==> 3mop + glu-L R_LEUTAm subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTAm equation: [m] : akg + leu-L <==> 4mop + glu-L

811012
stoichiometry: 1.0
species: 737955
type: SpeciesReference

754257
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: D-Xylulose 5-phosphate_C5H9O8P
type: Species

729066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726077
name: hexaglutamyl folate (THF)_C44H51N12O21
type: Species

785753
stoichiometry: 1.0
species: 732805
type: SpeciesReference

759353
stoichiometry: 1.0
species: 730922
type: SpeciesReference

831029
stoichiometry: 1.0
species: 741199
type: SpeciesReference

815268
stoichiometry: 1.0
species: 731755
type: SpeciesReference

804187
stoichiometry: 1.0
species: 727142
type: SpeciesReference

839522
stoichiometry: 1.0
species: 750622
type: SpeciesReference

032667
product: 774894
fast: false
reactant: 774833
product: 774906
notes: R_GLUCYS subsystem: Glutathione Metabolism R_GLUCYS equation: [c] : atp + cys-L + glu-L --> adp + glucys + h + pi
type: Reaction
product: 774870
reversible: false
is: ENSCAFG00000002288.2
is: ENSCAFG00000020126.2
reactant: 774846
name: gamma-glutamylcysteine synthetase
product: 774882
is: http://identifiers.org/ec-code/6.3.2.2
reactant: 774858

726826
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: cis-2-Hydroxy cinnamate_C9H7O3
type: Species

749104
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: O-Phospho-L-homoserine_C4H8NO6P
type: Species

799521
stoichiometry: 1.0
species: 730922
type: SpeciesReference

758303
stoichiometry: 1.0
species: 751687
type: SpeciesReference

756008
stoichiometry: 1.0
species: 751312
type: SpeciesReference

761041
stoichiometry: 2.0
species: 753591
type: SpeciesReference

776734
stoichiometry: 1.0
species: 740023
type: SpeciesReference

831174
stoichiometry: 2.0
species: 741151
type: SpeciesReference

747343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: Ammonium_H4N
type: Species

791389
stoichiometry: 1.0
species: 735673
type: SpeciesReference

846621
stoichiometry: 5.0
species: 741259
type: SpeciesReference

731273
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: S-Adenosyl-L-homocysteine_C14H20N6O5S
type: Species

818473
stoichiometry: 11.0
species: 753266
type: SpeciesReference

786461
stoichiometry: 1.0
species: 728245
type: SpeciesReference

770269
stoichiometry: 4.0
species: 746930
type: SpeciesReference

765560
stoichiometry: 1.0
species: 737019
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Oxalate_C2O4
type: Species

031198
reactant: 761222
product: 761283
is: ENSCAFG00000015315.2
type: Reaction
fast: false
product: 761271
notes: R_FATP3t subsystem: Transport, Extracellular R_FATP3t equation: na1[c] + ocdca[c] <==> na1[e] + ocdca[e] R_FATP1t subsystem: Transport, Extracellular R_FATP1t equation: hdca[c] + na1[c] <==> hdca[e] + na1[e] R_FATP2t subsystem: Transport, Extracellular R_FATP2t equation: na1[c] + ocdcea[c] <==> na1[e] + ocdcea[e]
product: 761258
product: 761295
reversible: true
reactant: 761210
reactant: 761246
reactant: 761234

801855
stoichiometry: 1.0
species: 752914
type: SpeciesReference

844918
stoichiometry: 1.0
species: 750393
type: SpeciesReference

764697
stoichiometry: 1.0
species: 739987
type: SpeciesReference

753810
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726065
name: w-hydroxyl arachidonic acid_C20H31O3
type: Species

749538
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _5-Diphosphoinositol pentakisphosphate_C6H6O27P7
type: Species

832124
stoichiometry: 1.0
species: 746134
type: SpeciesReference

783427
stoichiometry: 1.0
species: 741283
type: SpeciesReference

841653
stoichiometry: 1.0
species: 741259
type: SpeciesReference

738678
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO
type: Species

769818
stoichiometry: 1.0
species: 744399
type: SpeciesReference

753010
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: tetradecanoyl carnitine_C21H41NO4
type: Species

743540
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: keratan sulfate I, degradation product 41_C34H58N2O26
type: Species

805020
stoichiometry: 1.0
species: 745001
type: SpeciesReference

792751
stoichiometry: 1.0
species: 745483
type: SpeciesReference

843962
stoichiometry: 1.0
species: 743878
type: SpeciesReference

777854
stoichiometry: 11.0
species: 739741
type: SpeciesReference

773270
stoichiometry: 2.0
species: 732441
type: SpeciesReference

764384
stoichiometry: 2.0
species: 739754
type: SpeciesReference

783571
stoichiometry: 1.0
species: 753096
type: SpeciesReference

745423
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Lysine_C6H15N2O2
type: Species

787760
stoichiometry: 1.0
species: 737858
type: SpeciesReference

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stoichiometry: 1.0
species: 739827
type: SpeciesReference

843068
stoichiometry: 4.0
species: 741332
type: SpeciesReference

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stoichiometry: 15.0
species: 746086
type: SpeciesReference

728619
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Formyltetrahydrofolate_C20H21N7O7
type: Species

770534
stoichiometry: 1.0
species: 747185
type: SpeciesReference

817958
stoichiometry: 1.0
species: 727540
type: SpeciesReference

842026
stoichiometry: 1.0
species: 745013
type: SpeciesReference

801088
stoichiometry: 1.0
species: 747294
type: SpeciesReference

762143
stoichiometry: 1.0
species: 750405
type: SpeciesReference

841341
stoichiometry: 1.0
species: 733969
type: SpeciesReference

035323
is: http://identifiers.org/ec-code/4.2.1.1
product: 799569
reversible: true
fast: false
reactant: 799557
is: ENSCAFG00000019899.2
type: Reaction
name: carboxylic acid dissociation
reactant: 799545
is: ENSCAFG00000012150.2
notes: R_H2CO3Dm subsystem: Miscellaneous R_H2CO3Dm equation: [m] : co2 + h2o <==> h2co3

789131
stoichiometry: 1.0
species: 736073
type: SpeciesReference

037919
is: ENSCAFG00000003165.2
modifier: 824107
product: 824059
product: 824047
is: http://identifiers.org/ec-code/5.4.2.1
modifier: 824119
modifier: 824095
is: http://identifiers.org/ec-code/3.1.3.13
fast: false
notes: R_DPGase subsystem: Glycolysis/Gluconeogenesis R_DPGase equation: [c] : 23dpg + h2o --> 3pg + pi R_DPGM subsystem: Glycolysis/Gluconeogenesis R_DPGM equation: [c] : 13dpg <==> 23dpg + h R_PGM subsystem: Glycolysis/Gluconeogenesis R_PGM equation: [c] : 2pg <==> 3pg
modifier: 824083
reactant: 824035
reactant: 824023
modifier: 824071
type: Reaction
is: ENSCAFG00000009062.2
is: ENSCAFG00000002877.2
reversible: false

737786
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Estrone_C18H22O2
type: Species

777689
stoichiometry: 1.0
species: 735373
type: SpeciesReference

848691
stoichiometry: 1.0
species: 743288
type: SpeciesReference

842602
stoichiometry: 4.0
species: 747209
type: SpeciesReference

825531
stoichiometry: 1.0
species: 735228
type: SpeciesReference

811336
stoichiometry: 5.0
species: 732344
type: SpeciesReference

824360
stoichiometry: 1.0
species: 742394
type: SpeciesReference

816198
stoichiometry: 1.0
species: 732260
type: SpeciesReference

844349
stoichiometry: 5.0
species: 747050
type: SpeciesReference

771202
stoichiometry: 2.0
species: 747698
type: SpeciesReference

796683
stoichiometry: 1.0
species: 732200
type: SpeciesReference

810171
stoichiometry: 3.0
species: 734091
type: SpeciesReference

802169
stoichiometry: 2.0
species: 753302
type: SpeciesReference

794331
stoichiometry: 1.0
species: 733238
type: SpeciesReference

816909
stoichiometry: 1.0
species: 738750
type: SpeciesReference

769968
stoichiometry: 1.0
species: 747050
type: SpeciesReference

750177
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: O-Phospho-L-serine_C3H6NO6P
type: Species

784947
stoichiometry: 2.0
species: 731706
type: SpeciesReference

038598
reactant: 830241
product: 830337
product: 830265
is: http://identifiers.org/ec-code/3.1.6.12
is: ENSCAFG00000009168.2
reversible: true
product: 830277
reactant: 830217
product: 830289
type: Reaction
product: 830301
reactant: 830253
reactant: 830205
notes: R_S4TASE2ly subsystem: Chondroitin sulfate degradation R_S4TASE2ly equation: [l] : cs_a_deg3 + h2o <==> cs_a_deg4 + h + so4 R_S4TASE3ly subsystem: Chondroitin sulfate degradation R_S4TASE3ly equation: [l] : cs_b + h2o <==> cs_b_deg1 + h + so4 R_S4TASE1ly subsystem: Chondroitin sulfate degradation R_S4TASE1ly equation: [l] : cs_a + h2o <==> cs_a_deg1 + h + so4 R_S4TASE5ly subsystem: Chondroitin sulfate degradation R_S4TASE5ly equation: [l] : cs_e_deg4 + h2o <==> cs_e_deg5 + h + so4 R_S4TASE4ly subsystem: Chondroitin sulfate degradation R_S4TASE4ly equation: [l] : cs_e + h2o <==> cs_e_deg1 + h + so4
product: 830313
fast: false
product: 830325
reactant: 830229
reactant: 830193

819883
stoichiometry: 25.0
species: 739147
type: SpeciesReference

786184
stoichiometry: 1.0
species: 728824
type: SpeciesReference

853338
stoichiometry: 1.0
species: 731996
type: SpeciesReference

034444
product: 789843
product: 789831
reactant: 789759
product: 789807
type: Reaction
reactant: 789795
notes: R_PI345P3Pn subsystem: Inositol Phosphate Metabolism R_PI345P3Pn equation: [n] : h2o + pail345p_hs --> pail45p_hs + pi R_PI345P3P subsystem: Inositol Phosphate Metabolism R_PI345P3P equation: [c] : h2o + pail345p_hs --> pail45p_hs + pi
reactant: 789771
is: ENSCAFG00000015670.2
fast: false
reversible: false
reactant: 789783
is: http://identifiers.org/ec-code/3.1.3.67
product: 789819

854713
stoichiometry: 1.0
species: 751372
type: SpeciesReference

828772
stoichiometry: 1.0
species: 752790
type: SpeciesReference

758907
stoichiometry: 1.0
species: 737702
type: SpeciesReference

797481
stoichiometry: 1.0
species: 732805
type: SpeciesReference

806821
stoichiometry: 2.0
species: 726680
type: SpeciesReference

837616
stoichiometry: 2.0
species: 753326
type: SpeciesReference

823514
stoichiometry: 3.0
species: 735155
type: SpeciesReference

792414
stoichiometry: 1.0
species: 747099
type: SpeciesReference

773123
stoichiometry: 1.0
species: 730922
type: SpeciesReference

829890
stoichiometry: 1.0
species: 735216
type: SpeciesReference

742345
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: heparan sulfate, precursor 13_C79H116N5O92S9X
type: Species

850743
stoichiometry: 2.0
species: 741416
type: SpeciesReference

763427
stoichiometry: 1.0
species: 753230
type: SpeciesReference

775222
stoichiometry: 18.0
species: 740011
type: SpeciesReference

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stoichiometry: 1.0
species: 726973
type: SpeciesReference

735745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Deoxycytidine_C9H13N3O4
type: Species

727335
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
type: Species

849380
stoichiometry: 2.0
species: 743300
type: SpeciesReference

838349
stoichiometry: 4.0
species: 741223
type: SpeciesReference

758206
stoichiometry: 3.0
species: 741283
type: SpeciesReference

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reactant: 757467
reactant: 757455
product: 757516
is: ENSCAFG00000019517.2
fast: false
reactant: 757443
reversible: false
product: 757480
reactant: 757432
is: http://identifiers.org/ec-code/3.2.1.113
type: Reaction
product: 757504
notes: R_MAN1_7Ber subsystem: N-Glycan Biosynthesis R_MAN1_7Ber equation: [r] : g1m8masn + h2o --> g1m7masnB + man R_MAN1_6B1er subsystem: N-Glycan Biosynthesis R_MAN1_6B1er equation: [r] : g1m7masnC + h2o --> g1m6masnB1 + man R_MM8Ber subsystem: N-Glycan Biosynthesis R_MM8Ber equation: [r] : h2o + m8masn --> m7masnB + man
product: 757492

757651
stoichiometry: 2.0
species: 747074
type: SpeciesReference

739729
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: GDP-L-fucose_C16H23N5O15P2
type: Species

744808
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Leucine_C6H13NO2
type: Species

734054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Coenzyme A_C21H32N7O16P3S
type: Species

798740
stoichiometry: 6.0
species: 735721
type: SpeciesReference

813168
stoichiometry: 1.0
species: 745904
type: SpeciesReference

839113
stoichiometry: 1.0
species: 747148
type: SpeciesReference

806713
stoichiometry: 1.0
species: 749249
type: SpeciesReference

767339
stoichiometry: 1.0
species: 739027
type: SpeciesReference

788493
stoichiometry: 1.0
species: 751458
type: SpeciesReference

727576
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _3-Methylimidazoleacetic acid_C6H7N2O2
type: Species

727227
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726125
name: _3',5'-Cyclic GMP_C10H11N5O7P
type: Species

843262
stoichiometry: 1.0
species: 732332
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: L-Carnitine_C7H15NO3
type: Species

756419
stoichiometry: 2.0
species: 747209
type: SpeciesReference

847594
stoichiometry: 1.0
species: 746930
type: SpeciesReference

834883
stoichiometry: 1.0
species: 750902
type: SpeciesReference

839739
stoichiometry: 1.0
species: 745579
type: SpeciesReference

037351
notes: R_NH4t3r subsystem: Transport, Extracellular R_NH4t3r equation: h[e] + nh4[c] <==> h[c] + nh4[e]
fast: false
is: ENSCAFG00000016811.2
type: Reaction
is: ENSCAFG00000004004.1
product: 817487
reactant: 817451
name: ammonia transport via proton antiport
product: 817475
reversible: true
reactant: 817463

825314
stoichiometry: 1.0
species: 748531
type: SpeciesReference

816620
stoichiometry: 1.0
species: 746291
type: SpeciesReference

811926
stoichiometry: 1.0
species: 740205
type: SpeciesReference

734915
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 2_C45H66N2O49S4
type: Species

777252
stoichiometry: 1.0
species: 741259
type: SpeciesReference

789277
stoichiometry: 1.0
species: 737991
type: SpeciesReference

822743
stoichiometry: 1.0
species: 732465
type: SpeciesReference

756982
stoichiometry: 1.0
species: 744976
type: SpeciesReference

755634
stoichiometry: 2.0
species: 749200
type: SpeciesReference

852172
stoichiometry: 1.0
species: 731755
type: SpeciesReference

853121
stoichiometry: 1.0
species: 738039
type: SpeciesReference

801940
stoichiometry: 2.0
species: 741235
type: SpeciesReference

836930
stoichiometry: 15.0
species: 745928
type: SpeciesReference

852027
stoichiometry: 2.0
species: 741151
type: SpeciesReference

033815
is: ENSCAFG00000000644.2
reactant: 783922
fast: false
product: 783947
type: Reaction
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi
reactant: 783897
is: http://identifiers.org/ec-code/3.1.3.36
reactant: 783910
reversible: false
product: 783934
product: 783959

851298
stoichiometry: 2.0
species: 741500
type: SpeciesReference

838861
stoichiometry: 1.0
species: 730826
type: SpeciesReference

836665
stoichiometry: 1.0
species: 744447
type: SpeciesReference

793930
stoichiometry: 2.0
species: 747185
type: SpeciesReference

035047
is: http://identifiers.org/ec-code/2.4.2.1
modifier: 795130
modifier: 795106
modifier: 795118
modifier: 795178
product: 795045
modifier: 795154
reactant: 795021
reversible: false
modifier: 795274
modifier: 795190
type: Reaction
modifier: 795166
modifier: 795202
reactant: 795009
notes: R_PUNP5 subsystem: Purine Catabolism R_PUNP5 equation: [c] : ins + pi <==> hxan + r1p R_PUNP3 subsystem: Purine Catabolism R_PUNP3 equation: [c] : gsn + pi <==> gua + r1p R_PUNP4 subsystem: Purine Catabolism R_PUNP4 equation: [c] : dgsn + pi <==> 2dr1p + gua R_PUNP2 subsystem: Purine Catabolism R_PUNP2 equation: [c] : dad-2 + pi <==> 2dr1p + ade R_PUNP1 subsystem: Nucleotides R_PUNP1 equation: [c] : adn + pi <==> ade + r1p R_PUNP7 subsystem: Nucleotides R_PUNP7 equation: [c] : pi + xtsn <==> r1p + xan R_PUNP6 subsystem: Purine Catabolism R_PUNP6 equation: [c] : din + pi <==> 2dr1p + hxan R_DURIPP subsystem: Nucleotides R_DURIPP equation: [c] : duri + pi <==> 2dr1p + ura R_PNP subsystem: NAD Metabolism R_PNP equation: [c] : pi + rnam <==> h + ncam + r1p R_NP1 subsystem: NAD Metabolism R_NP1 equation: [c] : h + nac + r1p --> nicrns + pi
modifier: 795070
is: ENSCAFG00000005419.2
modifier: 795057
product: 795033
modifier: 795226
fast: false
modifier: 795142
modifier: 795214
reactant: 794997
modifier: 795094
modifier: 795262
modifier: 795082
modifier: 795238
modifier: 795250

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stoichiometry: 1.0
species: 744676
type: SpeciesReference

812082
stoichiometry: 1.0
species: 747050
type: SpeciesReference

794440
stoichiometry: 1.0
species: 729331
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: N-Acetylputrescine_C6H15N2O
type: Species

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stoichiometry: 17.0
species: 730307
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: (alpha-D-mannosyl)5-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C52H87N2O40X
type: Species

802012
stoichiometry: 2.0
species: 727347
type: SpeciesReference

825640
stoichiometry: 2.0
species: 749466
type: SpeciesReference

816041
stoichiometry: 1.0
species: 737326
type: SpeciesReference

814001
stoichiometry: 1.0
species: 747466
type: SpeciesReference

752866
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Testosterone_C19H28O2
type: Species

814747
stoichiometry: 1.0
species: 741308
type: SpeciesReference

828664
stoichiometry: 1.0
species: 737858
type: SpeciesReference

745290
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: gamma-linolenoyl-CoA_C39H60N7O17P3S
type: Species

757392
stoichiometry: 1.0
species: 731127
type: SpeciesReference

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stoichiometry: 103.0
species: 741308
type: SpeciesReference

790486
stoichiometry: 1.0
species: 735180
type: SpeciesReference

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stoichiometry: 1.0
species: 743685
type: SpeciesReference

792523
stoichiometry: 1.0
species: 747002
type: SpeciesReference

759630
stoichiometry: 1.0
species: 748591
type: SpeciesReference

842712
stoichiometry: 1.0
species: 726536
type: SpeciesReference

824252
stoichiometry: 1.0
species: 742431
type: SpeciesReference

797770
stoichiometry: 1.0
species: 751566
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: heparan sulfate, degradation product 5_C67H97N4O86S10
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726137
name: _3-Oxodecanoyl-CoA_C31H48N7O18P3S
type: Species

808481
stoichiometry: 1.0
species: 732344
type: SpeciesReference

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stoichiometry: 5.0
species: 751082
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Superoxide anion_O2
type: Species

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stoichiometry: 2.0
species: 731755
type: SpeciesReference

807507
stoichiometry: 1.0
species: 739877
type: SpeciesReference

850851
stoichiometry: 1.0
species: 747099
type: SpeciesReference

779049
stoichiometry: 1.0
species: 754159
type: SpeciesReference

823804
stoichiometry: 1.0
species: 729537
type: SpeciesReference

806605
stoichiometry: 4.0
species: 746918
type: SpeciesReference

768708
stoichiometry: 1.0
species: 747185
type: SpeciesReference

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stoichiometry: 1.0
species: 750104
type: SpeciesReference

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stoichiometry: 1.0
species: 748061
type: SpeciesReference

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stoichiometry: 1.0
species: 742660
type: SpeciesReference

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stoichiometry: 1.0
species: 732513
type: SpeciesReference

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product: 814564
is: ENSCAFG00000001290.2
reactant: 814504
product: 814614
reactant: 814516
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_ALR subsystem: Glycine, Serine, and Threonine Metabolism R_ALR equation: [c] : h2o + mthgxl + nadp --> (2) h + nadph + pyr R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_GALOR subsystem: Galactose metabolism R_GALOR equation: [c] : gal + h + nadph <==> galt + nadp R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
modifier: 814699
is: ENSCAFG00000025304.1
reactant: 814456
product: 814552
product: 814540
product: 814639
modifier: 814687
modifier: 814651
product: 814589
product: 814528
reactant: 814444
is: http://identifiers.org/ec-code/1.1.1.2
fast: false
reversible: false
reactant: 814492
modifier: 814675
reactant: 814432
reactant: 814420
type: Reaction
product: 814627
modifier: 814663
is: ENSCAFG00000024828.1
reactant: 814480
product: 814577
is: http://identifiers.org/ec-code/1.1.1.21
reactant: 814468

038489
is: http://identifiers.org/ec-code/2.7.4.3
reactant: 829506
is: ENSCAFG00000013746.2
is: ENSCAFG00000012522.2
name: adenylate kinase, mitochondrial
product: 829530
is: ENSCAFG00000010390.2
reversible: true
fast: false
is: ENSCAFG00000000211.1
notes: R_ADK1m subsystem: Nucleotides R_ADK1m equation: [m] : amp + atp <==> (2) adp
is: ENSCAFG00000015156.2
reactant: 829518
type: Reaction
is: ENSCAFG00000018611.2

750068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: Prostaglandin H2_C20H31O5
type: Species

819992
stoichiometry: 1.0
species: 744350
type: SpeciesReference

765790
stoichiometry: 1.0
species: 741729
type: SpeciesReference

766931
stoichiometry: 1.0
species: 732260
type: SpeciesReference

036422
type: Reaction
reactant: 808962
is: ENSCAFG00000023963.1
reversible: true
reactant: 808974
reactant: 808986
product: 808998
notes: R_CITtbm subsystem: Transport, Mitochondrial R_CITtbm equation: cit[c] + pep[m] <==> cit[m] + pep[c] R_CITtam subsystem: Transport, Mitochondrial R_CITtam equation: cit[c] + mal-L[m] <==> cit[m] + mal-L[c]
product: 809010
product: 809022
fast: false

756872
stoichiometry: 1.0
species: 735023
type: SpeciesReference

765851
stoichiometry: 1.0
species: 749346
type: SpeciesReference

832989
stoichiometry: 3.0
species: 745543
type: SpeciesReference

817090
stoichiometry: 1.0
species: 739244
type: SpeciesReference

040368
reversible: true
product: 846318
reactant: 846306
type: Reaction
reactant: 846294
fast: false
is: http://identifiers.org/ec-code/1.1.1.105
is: ENSCAFG00000000148.2
name: retinol dehydrogenase (all-trans)
notes: R_RDH1 subsystem: Vitamin A Metabolism R_RDH1 equation: [c] : nad + retinol <==> h + nadh + retinal
product: 846330
product: 846342

822851
stoichiometry: 1.0
species: 741223
type: SpeciesReference

827281
stoichiometry: 3.0
species: 739852
type: SpeciesReference

845944
stoichiometry: 18.0
species: 730946
type: SpeciesReference

778916
stoichiometry: 5.0
species: 741151
type: SpeciesReference

813011
stoichiometry: 2.0
species: 741259
type: SpeciesReference

847032
stoichiometry: 1.0
species: 743408
type: SpeciesReference

732308
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: L-Ascorbate_C6H8O6
type: Species

034336
is: ENSCAFG00000009089.2
reversible: false
product: 789180
notes: R_SERHL subsystem: Glycine, Serine, and Threonine Metabolism R_SERHL equation: [c] : ser-L --> 2amac + h2o R_THRD_L subsystem: Glycine, Serine, and Threonine Metabolism R_THRD_L equation: [c] : thr-L --> 2obut + nh4
type: Reaction
fast: false
reactant: 789167
product: 789204
is: http://identifiers.org/ec-code/4.3.1.19
product: 789216
product: 789192
reactant: 789155

847812
stoichiometry: 5.0
species: 740180
type: SpeciesReference

785079
stoichiometry: 2.0
species: 741332
type: SpeciesReference

773559
stoichiometry: 1.0
species: 740168
type: SpeciesReference

035937
fast: false
notes: R_PIt8 subsystem: Transport, Extracellular R_PIt8 equation: (1.5) na1[e] + pi[e] <==> (1.5) na1[c] + pi[c]
type: Reaction
is: ENSCAFG00000007200.2
reversible: true
reactant: 803968
product: 803992
is: ENSCAFG00000005472.2
product: 804004
reactant: 803980
name: phosphate transport in/out via Na+ symporter

752962
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: Thiosulfate_O3S2
type: Species

855110
stoichiometry: 1.0
species: 741826
type: SpeciesReference

762494
stoichiometry: 4.0
species: 741332
type: SpeciesReference

821775
stoichiometry: 1.0
species: 738414
type: SpeciesReference

769698
stoichiometry: 1.0
species: 735023
type: SpeciesReference

837820
stoichiometry: 1.0
species: 727202
type: SpeciesReference

762567
stoichiometry: 1.0
species: 730585
type: SpeciesReference

793078
stoichiometry: 1.0
species: 745603
type: SpeciesReference

845148
stoichiometry: 1.0
species: 733738
type: SpeciesReference

728269
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _4-Nitrophenol_C6H5NO3
type: Species

854376
stoichiometry: 1.0
species: 738123
type: SpeciesReference

844459
stoichiometry: 3.0
species: 733933
type: SpeciesReference

755743
stoichiometry: 1.0
species: 746978
type: SpeciesReference

740994
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726113
name: GTP_C10H12N5O14P3
type: Species

825988
stoichiometry: 2.0
species: 735373
type: SpeciesReference

791039
stoichiometry: 1.0
species: 749815
type: SpeciesReference

760478
stoichiometry: 1.0
species: 750938
type: SpeciesReference

797909
stoichiometry: 1.0
species: 731102
type: SpeciesReference

847245
stoichiometry: 1.0
species: 741259
type: SpeciesReference

037242
reactant: 816137
product: 816210
product: 816173
is: ENSCAFG00000025499.1
is: ENSCAFG00000025568.1
product: 816246
reactant: 816089
is: ENSCAFG00000025557.1
notes: R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_HOMt4 subsystem: Transport, Extracellular R_HOMt4 equation: hom-L[e] + na1[e] --> hom-L[c] + na1[c] R_ORNtiDF subsystem: Transport, Extracellular R_ORNtiDF equation: orn[e] --> orn[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_ARGtiDF subsystem: Transport, Extracellular R_ARGtiDF equation: arg-L[e] --> arg-L[c] R_LYStiDF subsystem: Transport, Extracellular R_LYStiDF equation: lys-L[e] --> lys-L[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c]
product: 816198
is: ENSCAFG00000002736.2
reactant: 816125
reactant: 816101
product: 816234
reactant: 816161
is: ENSCAFG00000016278.2
is: ENSCAFG00000025484.1
type: Reaction
product: 816186
reversible: false
is: ENSCAFG00000016289.2
reactant: 816077
reactant: 816149
is: ENSCAFG00000006660.2
product: 816258
is: ENSCAFG00000016908.2
is: ENSCAFG00000024414.1
fast: false
is: ENSCAFG00000006653.1
reactant: 816113
is: ENSCAFG00000006944.2
is: ENSCAFG00000012267.2
product: 816222

835171
stoichiometry: 1.0
species: 744510
type: SpeciesReference

031439
is: ENSCAFG00000014308.2
type: Reaction
name: _5-aminolevulinate synthase
is: ENSCAFG00000009881.2
reactant: 763500
notes: R_ALASm subsystem: Glycine, Serine, and Threonine Metabolism R_ALASm equation: [m] : gly + h + succoa --> 5aop + co2 + coa
product: 763548
reactant: 763512
product: 763536
product: 763524
reversible: false
is: http://identifiers.org/ec-code/2.3.1.37
fast: false
reactant: 763488

841233
stoichiometry: 3.0
species: 747722
type: SpeciesReference

839005
stoichiometry: 1.0
species: 740639
type: SpeciesReference

739839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726089
name: D-Glucose_C6H12O6
type: Species

757030
stoichiometry: 1.0
species: 751591
type: SpeciesReference

726175
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19
type: Species

803760
stoichiometry: 2.0
species: 746061
type: SpeciesReference

817802
stoichiometry: 1.0
species: 737326
type: SpeciesReference

733542
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: Choline phosphate_C5H13NO4P
type: Species

750806
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726101
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57
type: Species

037665
modifier: 821523
reversible: false
modifier: 821426
modifier: 821450
modifier: 821571
modifier: 821535
modifier: 821475
fast: false
modifier: 821595
modifier: 821583
modifier: 821547
modifier: 821487
modifier: 821631
modifier: 821462
modifier: 821643
modifier: 821499
modifier: 821607
modifier: 821655
reactant: 821402
modifier: 821619
is: ENSCAFG00000012739.2
modifier: 821667
modifier: 821679
modifier: 821438
modifier: 821559
modifier: 821511
product: 821414
type: Reaction
notes: R_ADNt subsystem: Transport, Extracellular R_ADNt equation: adn[e] <==> adn[c] R_INSt subsystem: Transport, Extracellular R_INSt equation: ins[e] <==> ins[c] R_HYXNt subsystem: Transport, Extracellular R_HYXNt equation: hxan[e] <==> hxan[c] R_URIt subsystem: Transport, Extracellular R_URIt equation: uri[e] <==> uri[c] R_GSNt subsystem: Transport, Extracellular R_GSNt equation: gsn[e] <==> gsn[c] R_CSNt subsystem: Transport, Extracellular R_CSNt equation: csn[e] <==> csn[c] R_URAt subsystem: Transport, Extracellular R_URAt equation: ura[e] <==> ura[c] R_ADEt subsystem: Transport, Extracellular R_ADEt equation: ade[e] <==> ade[c] R_GUAt subsystem: Transport, Extracellular R_GUAt equation: gua[e] <==> gua[c] R_THYMt subsystem: Transport, Extracellular R_THYMt equation: thym[e] <==> thym[c] R_THYMDt1 subsystem: Transport, Extracellular R_THYMDt1 equation: thymd[e] --> thymd[c] R_CYTDt subsystem: Transport, Extracellular R_CYTDt equation: cytd[e] <==> cytd[c]

792643
stoichiometry: 1.0
species: 739987
type: SpeciesReference

749646
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: _5-Phospho-beta-D-ribosylamine_C5H11NO7P
type: Species

747454
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 726053
name: NMN_C11H14N2O8P
type: Species

799088
stoichiometry: 1.0
species: 740554
type: SpeciesReference

778795
stoichiometry: 2.0
species: 745037
type: SpeciesReference

841761
stoichiometry: 1.0
species: 741211
type: SpeciesReference