054122
stoichiometry: 1.0
species: 030746
type: SpeciesReference

039008
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Malate_C4H4O5
type: Species

129488
stoichiometry: 2.0
species: 025577
type: SpeciesReference

041874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Phosphocreatine_C4H9N3O5P
type: Species

072815
stoichiometry: 1.0
species: 024792
type: SpeciesReference

128510
stoichiometry: 1.0
species: 030066
type: SpeciesReference

087269
stoichiometry: 1.0
species: 035435
type: SpeciesReference

130455
stoichiometry: 23.0
species: 034363
type: SpeciesReference

106896
stoichiometry: 1.0
species: 020617
type: SpeciesReference

062294
stoichiometry: 1.0
species: 032911
type: SpeciesReference

927990
product: 087244
is: ENSMMUG00000014056.2
fast: false
notes: R_S2T4g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T4g equation: [g] : hs_pre11 + (2) paps --> (2) h + hs_pre12 + (2) pap
name: uronyl 2-sulfotransferase, Golgi
reactant: 087232
reactant: 087220
product: 087256
product: 087269
type: Reaction
reversible: false

058650
stoichiometry: 1.0
species: 042283
type: SpeciesReference

044560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S
type: Species

035049
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: heptadecanoyl carnitine_C24H47NO4
type: Species

928987
reversible: false
is: http://identifiers.org/ec-code/1.13.11.42
reactant: 097227
reactant: 097251
notes: R_SRTN23OX subsystem: Tryptophan metabolism R_SRTN23OX equation: [c] : o2 + srtn --> f5hoxkyn R_MELATN23DOX subsystem: Tryptophan metabolism R_MELATN23DOX equation: [c] : melatn + o2 --> fna5moxam R_5HTRPDOX subsystem: Tryptophan metabolism R_5HTRPDOX equation: [c] : 5htrp + o2 --> 5hoxnfkyn
fast: false
product: 097275
reactant: 097239
product: 097287
product: 097263
reactant: 097215
type: Reaction
is: ENSMMUG00000016206.2

035326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 4_C73H104N4O92S10
type: Species

926909
product: 077037
reactant: 077025
notes: R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c]
is: ENSMMUG00000003565.2
fast: false
reversible: true
name: Urea transport via facilitate diffusion
type: Reaction

095391
stoichiometry: 3.0
species: 034179
type: SpeciesReference

076749
stoichiometry: 1.0
species: 035593
type: SpeciesReference

048584
stoichiometry: 2.0
species: 028680
type: SpeciesReference

084590
stoichiometry: 1.0
species: 044585
type: SpeciesReference

078501
stoichiometry: 1.0
species: 020386
type: SpeciesReference

141498
stoichiometry: 1.0
species: 033930
type: SpeciesReference

077473
stoichiometry: 1.0
species: 021050
type: SpeciesReference

021400
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: D-4'-Phosphopantothenate_C9H15NO8P
type: Species

115068
stoichiometry: 1.0
species: 027290
type: SpeciesReference

108936
stoichiometry: 1.0
species: 021243
type: SpeciesReference

117414
stoichiometry: 1.0
species: 028981
type: SpeciesReference

029372
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Dehydroepiandrosterone_C19H28O2
type: Species

071003
stoichiometry: 1.0
species: 031871
type: SpeciesReference

151331
stoichiometry: 1.0
species: 025396
type: SpeciesReference

135903
stoichiometry: 1.0
species: 044259
type: SpeciesReference

112394
stoichiometry: 1.0
species: 030249
type: SpeciesReference

025879
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Biotinyl-5'-AMP_C20H27N7O9PS
type: Species

040174
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2
type: Species

148541
stoichiometry: 1.0
species: 024154
type: SpeciesReference

024166
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: adrenic acid_C22H35O2
type: Species

924124
product: 052568
fast: false
type: Reaction
reactant: 052520
reactant: 052544
product: 052580
name: phosphatidylcholine transporter
product: 052556
product: 052592
reversible: true
is: ENSMMUG00000010788.2
reactant: 052532
notes: R_PCt subsystem: Transport, Extracellular R_PCt equation: atp[c] + h2o[c] + pchol_hs[c] <==> adp[c] + h[c] + pchol_hs[e] + pi[c]

066221
stoichiometry: 2.0
species: 034363
type: SpeciesReference

123469
stoichiometry: 1.0
species: 041283
type: SpeciesReference

104391
stoichiometry: 2.0
species: 040017
type: SpeciesReference

036401
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 23_C124H201N8O106S5
type: Species

070285
stoichiometry: 1.0
species: 039402
type: SpeciesReference

105692
stoichiometry: 1.0
species: 042439
type: SpeciesReference

931933
reactant: 126399
product: 126448
product: 126436
notes: R_GluForTx subsystem: Histidine Metabolism R_GluForTx equation: [c] : forglu + h + thf --> 5forthf + glu-L R_FTCD subsystem: Folate Metabolism R_FTCD equation: [c] : 5forthf + (2) h --> methf + nh4
is: ENSMMUG00000022324.2
fast: false
reactant: 126387
is: http://identifiers.org/ec-code/4.3.1.4
reversible: false
is: http://identifiers.org/ec-code/2.1.2.5
product: 126460
reactant: 126375
type: Reaction
reactant: 126412
product: 126424

075230
stoichiometry: 4.0
species: 034277
type: SpeciesReference

933652
is: http://identifiers.org/ec-code/1.1.1.105
product: 142693
notes: R_RDH1 subsystem: Vitamin A Metabolism R_RDH1 equation: [c] : nad + retinol <==> h + nadh + retinal
type: Reaction
reversible: true
product: 142717
reactant: 142680
name: retinol dehydrogenase (all-trans)
product: 142705
fast: false
is: ENSMMUG00000003763.2
reactant: 142668

025517
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Aspartate_C4H6NO4
type: Species

137205
stoichiometry: 1.0
species: 035483
type: SpeciesReference

086909
stoichiometry: 1.0
species: 034363
type: SpeciesReference

105067
stoichiometry: 1.0
species: 042331
type: SpeciesReference

927461
reactant: 082589
reactant: 082601
is: ENSMMUG00000020665.2
reversible: false
product: 082637
type: Reaction
product: 082625
fast: false
notes: R_SERHL subsystem: Glycine, Serine, and Threonine Metabolism R_SERHL equation: [c] : ser-L --> 2amac + h2o R_THRD_L subsystem: Glycine, Serine, and Threonine Metabolism R_THRD_L equation: [c] : thr-L --> 2obut + nh4
is: http://identifiers.org/ec-code/4.3.1.19
product: 082649
product: 082613
is: ENSMMUG00000004208.2

050939
stoichiometry: 1.0
species: 027073
type: SpeciesReference

924412
product: 054881
reactant: 054809
product: 054857
is: ENSMMUG00000005389.2
reactant: 054796
reversible: false
fast: false
reactant: 054845
product: 054930
product: 054905
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6ET3er equation: [r] : m2emgacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs R_H4ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ET3er equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + em3gacpail_hs R_M4CET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4CET3er equation: [r] : m3emgacpail_hs + pe_hs --> dag_hs + mem2emgacpail_hs
reactant: 054772
reactant: 054784
reactant: 054821
product: 054918
reactant: 054833
type: Reaction
product: 054869
product: 054893

103765
stoichiometry: 1.0
species: 039571
type: SpeciesReference

120044
stoichiometry: 1.0
species: 024226
type: SpeciesReference

070586
stoichiometry: 5.0
species: 034375
type: SpeciesReference

026832
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Chloride_Cl
type: Species

031738
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
type: Species

066113
stoichiometry: 1.0
species: 023478
type: SpeciesReference

088209
stoichiometry: 1.0
species: 027205
type: SpeciesReference

142439
stoichiometry: 1.0
species: 021678
type: SpeciesReference

068186
stoichiometry: 4.0
species: 031931
type: SpeciesReference

035025
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: heptadecanoyl coa_C38H64N7O17P3S
type: Species

129260
stoichiometry: 1.0
species: 029474
type: SpeciesReference

101638
stoichiometry: 1.0
species: 019719
type: SpeciesReference

030783
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Estradiol_C18H24O2
type: Species

064453
stoichiometry: 1.0
species: 021424
type: SpeciesReference

113936
stoichiometry: 24.0
species: 046391
type: SpeciesReference

933916
fast: false
reactant: 146925
product: 147059
reactant: 146986
is: ENSMMUG00000006697.2
product: 147023
product: 147071
is: ENSMMUG00000006891.2
product: 147083
product: 147035
reactant: 146950
product: 147095
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_LALDO2x subsystem: Pyruvate Metabolism R_LALDO2x equation: [c] : h + mthgxl + nadh --> lald-D + nad R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_PPDOx subsystem: Pyruvate Metabolism R_PPDOx equation: [c] : h + lald-D + nadh --> 12ppd-R + nad R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
reactant: 146937
reactant: 147011
reactant: 146999
reactant: 146962
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.21
product: 147107
reactant: 146974
reversible: false
product: 147047

078850
stoichiometry: 1.0
species: 045477
type: SpeciesReference

110656
stoichiometry: 1.0
species: 041295
type: SpeciesReference

141282
stoichiometry: 1.0
species: 025541
type: SpeciesReference

135637
stoichiometry: 2.0
species: 040017
type: SpeciesReference

125483
stoichiometry: 4.0
species: 040270
type: SpeciesReference

048175
stoichiometry: 5.0
species: 023514
type: SpeciesReference

134134
stoichiometry: 5.0
species: 040017
type: SpeciesReference

114611
stoichiometry: 1.0
species: 036521
type: SpeciesReference

053832
stoichiometry: 1.0
species: 037329
type: SpeciesReference

049683
stoichiometry: 1.0
species: 030783
type: SpeciesReference

149095
stoichiometry: 1.0
species: 039559
type: SpeciesReference

042391
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S
type: Species

085746
stoichiometry: 1.0
species: 034436
type: SpeciesReference

061466
stoichiometry: 1.0
species: 020070
type: SpeciesReference

932871
product: 135601
reactant: 135493
product: 135565
is: http://identifiers.org/ec-code/3.10.1.1
reversible: false
reactant: 135481
product: 135541
notes: R_HS1ly subsystem: Heparan sulfate degradation R_HS1ly equation: [l] : h2o + hs_deg1 --> h + hs_deg2 + so4 R_HS2ly subsystem: Heparan sulfate degradation R_HS2ly equation: [l] : h2o + hs_deg6 --> h + hs_deg7 + so4 R_HS4ly subsystem: Heparan sulfate degradation R_HS4ly equation: [l] : h2o + hs_deg18 --> h + hs_deg19 + so4 R_HS3ly subsystem: Heparan sulfate degradation R_HS3ly equation: [l] : h2o + hs_deg12 --> h + hs_deg13 + so4
fast: false
reactant: 135529
product: 135577
reactant: 135517
is: ENSMMUG00000002849.2
reactant: 135505
product: 135589
product: 135553
type: Reaction

071438
stoichiometry: 2.0
species: 042548
type: SpeciesReference

078621
stoichiometry: 3.0
species: 034387
type: SpeciesReference

930855
reversible: false
product: 116366
is: http://identifiers.org/ec-code/1.4.3.4
reactant: 116268
product: 116402
product: 116317
product: 116305
reactant: 116219
reactant: 116232
reactant: 116158
reactant: 116195
product: 116378
product: 116426
reactant: 116122
product: 116341
product: 116329
product: 116293
notes: R_3MOXTYROX subsystem: Tyrosine metabolism R_3MOXTYROX equation: [c] : 3moxtyr + h2o + o2 --> 3mox4hpac + h2o2 + nh4 R_MAOLNOR subsystem: Tyrosine metabolism R_MAOLNOR equation: [c] : h2o + normete-L + o2 --> 3m4hpga + h2o2 + nh4 R_APRTO2 subsystem: Arginine and Proline Metabolism R_APRTO2 equation: [c] : aprut + h2o + o2 --> h2o2 + n4abutn + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_3HXKYNOXDA subsystem: Tryptophan metabolism R_3HXKYNOXDA equation: [c] : 3hxkynam + o2 --> 48dhoxquin + h2o2 + nh4 R_41R2A1H12BOOX subsystem: Tyrosine metabolism R_41R2A1H12BOOX equation: [c] : h2o + nrpphr + o2 --> 34dhmald + h2o2 + nh4 R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_5HXKYNOXDA subsystem: Tryptophan metabolism R_5HXKYNOXDA equation: [c] : 5hxkynam + o2 --> 46dhoxquin + h2o2 + nh4 R_TYROXDAc subsystem: Tyrosine metabolism R_TYROXDAc equation: [c] : h2o + o2 + tym --> 4hoxpacd + h2o2 + nh4 R_5HOXINOXDA subsystem: Tryptophan metabolism R_5HOXINOXDA equation: [c] : h2o + o2 + srtn --> 5hoxindact + h2o2 + nh4 R_41R1H2MAE12BOOX subsystem: Tyrosine metabolism R_41R1H2MAE12BOOX equation: [c] : adrnl + h2o + o2 --> 34dhmald + h2o2 + mma
reactant: 116256
is: ENSMMUG00000019489.2
product: 116414
product: 116281
fast: false
reactant: 116146
is: http://identifiers.org/ec-code/1.4.3.6
reactant: 116183
reactant: 116244
product: 116353
product: 116438
product: 116390
type: Reaction
reactant: 116170
reactant: 116207
reactant: 116134
reactant: 116110

074110
stoichiometry: 1.0
species: 022522
type: SpeciesReference

075798
stoichiometry: 1.0
species: 024010
type: SpeciesReference

030030
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10
type: Species

065091
stoichiometry: 10.0
species: 040017
type: SpeciesReference

041295
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Ornithine_C5H13N2O2
type: Species

051914
stoichiometry: 1.0
species: 041319
type: SpeciesReference

145455
stoichiometry: 1.0
species: 037220
type: SpeciesReference

109453
stoichiometry: 1.0
species: 045381
type: SpeciesReference

046079
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: tetradecenoate (n-C14:1)_C14H25O2
type: Species

033445
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Glycolate_C2H3O3
type: Species

141137
stoichiometry: 1.0
species: 037693
type: SpeciesReference

926741
product: 075988
reactant: 075926
reactant: 075939
reactant: 075952
reactant: 075913
product: 076012
is: ENSMMUG00000017472.2
product: 076000
product: 075976
reversible: false
fast: false
product: 075964
notes: R_DOLPGT2_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT2_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g1m8mpdol_L --> (0.1) dolp_L + (0.1) g2m8mpdol_L + h R_DOLPGT2_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT2_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g1m8mpdol_U --> (0.1) dolp_U + (0.1) g2m8mpdol_U + h
type: Reaction

073034
stoichiometry: 1.0
species: 040017
type: SpeciesReference

036149
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: ITP_C10H11N4O14P3
type: Species

925528
reactant: 065945
product: 066053
reversible: false
reactant: 065909
is: ENSMMUG00000001871.2
reactant: 065897
product: 066017
reactant: 065885
reactant: 065933
reactant: 065873
reactant: 065861
product: 065993
product: 065957
reactant: 065921
product: 066041
type: Reaction
fast: false
reactant: 065849
is: http://identifiers.org/ec-code/1.4.3.4
product: 066029
product: 066005
product: 065969
notes: R_PTRCOX1 subsystem: Arginine and Proline Metabolism R_PTRCOX1 equation: [c] : h2o + o2 + ptrc --> 4abutn + h2o2 + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_NMPTRCOX subsystem: Alkaloid biosynthesis II R_NMPTRCOX equation: [c] : nmptrc + o2 --> 1mpyr + h2o2 + nh4 R_MHISOR subsystem: Histidine Metabolism R_MHISOR equation: [c] : h2o + mhista + o2 --> 3mldz + h2o2 + nh4 R_AACTOOR subsystem: Glycine, Serine, and Threonine Metabolism R_AACTOOR equation: [c] : aact + h2o + o2 --> h2o2 + mthgxl + nh4 R_MAOX subsystem: Tyrosine metabolism R_MAOX equation: [c] : h2o + mma + o2 --> fald + h2o2 + nh4 R_13DAMPPOX subsystem: beta-Alanine metabolism R_13DAMPPOX equation: [c] : 13dampp + h2o + o2 --> bamppald + h2o2 + nh4
is: http://identifiers.org/ec-code/1.4.3.6
product: 065981

082456
stoichiometry: 1.0
species: 028812
type: SpeciesReference

096794
stoichiometry: 1.0
species: 025529
type: SpeciesReference

060770
stoichiometry: 1.0
species: 030066
type: SpeciesReference

084350
stoichiometry: 1.0
species: 024130
type: SpeciesReference

038176
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: linoelaidyl coenzyme A_C39H62N7O17P3S
type: Species

029223
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _6,7-Dihydrobiopterin_C9H13N5O3
type: Species

138398
stoichiometry: 1.0
species: 034363
type: SpeciesReference

059829
stoichiometry: 1.0
species: 025505
type: SpeciesReference

088907
stoichiometry: 1.0
species: 043476
type: SpeciesReference

065163
stoichiometry: 1.0
species: 042956
type: SpeciesReference

139785
stoichiometry: 1.0
species: 042331
type: SpeciesReference

060998
stoichiometry: 1.0
species: 034412
type: SpeciesReference

039981
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N4-Acetylaminobutanal_C6H11NO2
type: Species

050649
stoichiometry: 3.0
species: 034327
type: SpeciesReference

108077
stoichiometry: 4.0
species: 031339
type: SpeciesReference

047754
stoichiometry: 1.0
species: 042860
type: SpeciesReference

124965
stoichiometry: 1.0
species: 029199
type: SpeciesReference

041138
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)_C29H53N2O8PRS
type: Species

035593
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate proteoglycan_C79H113N5O101S12X
type: Species

148662
stoichiometry: 2.0
species: 026710
type: SpeciesReference

030637
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S
type: Species

059278
stoichiometry: 1.0
species: 038333
type: SpeciesReference

063778
stoichiometry: 1.0
species: 040162
type: SpeciesReference

094173
stoichiometry: 1.0
species: 039764
type: SpeciesReference

090588
stoichiometry: 1.0
species: 042524
type: SpeciesReference

133742
stoichiometry: 3.0
species: 031133
type: SpeciesReference

121296
stoichiometry: 1.0
species: 041657
type: SpeciesReference

106005
stoichiometry: 1.0
species: 024804
type: SpeciesReference

028547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dAMP_C10H12N5O6P
type: Species

064717
stoichiometry: 1.0
species: 042572
type: SpeciesReference

138941
stoichiometry: 3.0
species: 025541
type: SpeciesReference

089994
stoichiometry: 1.0
species: 021123
type: SpeciesReference

033542
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: glycogen, structure 5 (glycogenin-2[1,4-Glc])_C12H21O11X
type: Species

106428
stoichiometry: 1.0
species: 037790
type: SpeciesReference

031411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Folate_C19H18N7O6
type: Species

140183
stoichiometry: 1.0
species: 037609
type: SpeciesReference

127640
stoichiometry: 1.0
species: 025565
type: SpeciesReference

126279
stoichiometry: 2.0
species: 041742
type: SpeciesReference

022220
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: heptaglutamyl folate (DHF)_C49H55N13O24
type: Species

061442
stoichiometry: 1.0
species: 044778
type: SpeciesReference

111703
stoichiometry: 1.0
species: 046863
type: SpeciesReference

044005
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Se-Adenosylselenohomocysteine_C14H20N6O5Se
type: Species

081791
stoichiometry: 1.0
species: 031169
type: SpeciesReference

067740
stoichiometry: 4.0
species: 025541
type: SpeciesReference

085071
stoichiometry: 1.0
species: 034002
type: SpeciesReference

113669
stoichiometry: 1.0
species: 034241
type: SpeciesReference

102687
stoichiometry: 1.0
species: 029090
type: SpeciesReference

102253
stoichiometry: 1.0
species: 029837
type: SpeciesReference

037934
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Leukotriene B4_C20H31O4
type: Species

056866
stoichiometry: 1.0
species: 044790
type: SpeciesReference

131811
stoichiometry: 1.0
species: 037390
type: SpeciesReference

059061
stoichiometry: 1.0
species: 026059
type: SpeciesReference

145188
stoichiometry: 1.0
species: 036221
type: SpeciesReference

063090
stoichiometry: 8.0
species: 041754
type: SpeciesReference

037256
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate II (core 2-linked), degradation product 6_C44H72N4O33SX
type: Species

147071
stoichiometry: 6.0
species: 040198
type: SpeciesReference

048706
stoichiometry: 2.0
species: 042283
type: SpeciesReference

042223
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: _2-Hydroxyphytanoyl-CoA_C41H70N7O18P3S
type: Species

069995
stoichiometry: 1.0
species: 044754
type: SpeciesReference

117836
stoichiometry: 1.0
species: 030042
type: SpeciesReference

927173
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2
is: ENSMMUG00000015754.2
reactant: 079214
is: ENSMMUG00000021772.2
is: http://identifiers.org/ec-code/1.3.99.3
product: 079250
reactant: 079202
is: ENSMMUG00000006338.2
product: 079238
reversible: false
product: 079226
type: Reaction
fast: false
reactant: 079190
is: http://identifiers.org/ec-code/1.3.99.2

057167
stoichiometry: 1.0
species: 034929
type: SpeciesReference

064320
stoichiometry: 2.0
species: 026977
type: SpeciesReference

924700
is: http://identifiers.org/ec-code/2.4.1.83
product: 057625
product: 057600
is: ENSMMUG00000002759.2
notes: R_DOLPMT_L subsystem: N-Glycan Biosynthesis R_DOLPMT_L equation: [c] : (0.1) dolp_L + gdpmann --> (0.1) dolmanp_L + gdp R_DOLPMT_U subsystem: N-Glycan Biosynthesis R_DOLPMT_U equation: [c] : (0.1) dolp_U + gdpmann --> (0.1) dolmanp_U + gdp
fast: false
reversible: false
product: 057613
reactant: 057564
type: Reaction
reactant: 057588
reactant: 057576
is: ENSMMUG00000019036.2

075083
stoichiometry: 1.0
species: 032826
type: SpeciesReference

019253
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19
type: Species

091402
stoichiometry: 1.0
species: 037052
type: SpeciesReference

147299
stoichiometry: 1.0
species: 039237
type: SpeciesReference

119136
stoichiometry: 1.0
species: 034253
type: SpeciesReference

068380
stoichiometry: 1.0
species: 046199
type: SpeciesReference

098982
stoichiometry: 1.0
species: 045297
type: SpeciesReference

029776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

069839
stoichiometry: 1.0
species: 026432
type: SpeciesReference

098476
stoichiometry: 1.0
species: 026916
type: SpeciesReference

019671
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _18 hydroxy arachidonic acid_C20H31O3
type: Species

134688
stoichiometry: 1.0
species: 033251
type: SpeciesReference

047645
stoichiometry: 1.0
species: 035253
type: SpeciesReference

084241
stoichiometry: 1.0
species: 031133
type: SpeciesReference

047537
stoichiometry: 1.0
species: 038947
type: SpeciesReference

100974
stoichiometry: 1.0
species: 043452
type: SpeciesReference

077845
stoichiometry: 10.0
species: 024010
type: SpeciesReference

090238
stoichiometry: 1.0
species: 047417
type: SpeciesReference

045839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Reduced thioredoxin_XH2
type: Species

134532
stoichiometry: 1.0
species: 030054
type: SpeciesReference

055766
stoichiometry: 1.0
species: 023671
type: SpeciesReference

934312
product: 150137
reactant: 150125
type: Reaction
is: ENSMMUG00000016623.2
notes: R_UPPDC1 subsystem: Heme Biosynthesis R_UPPDC1 equation: [c] : (4) h + uppg3 --> (4) co2 + cpppg3
reactant: 150113
is: http://identifiers.org/ec-code/4.1.1.37
reversible: false
name: uroporphyrinogen decarboxylase (uroporphyrinogen III)
product: 150149
fast: false

120321
stoichiometry: 1.0
species: 038260
type: SpeciesReference

136193
stoichiometry: 1.0
species: 040270
type: SpeciesReference

052243
stoichiometry: 1.0
species: 029372
type: SpeciesReference

119850
stoichiometry: 1.0
species: 045729
type: SpeciesReference

101506
stoichiometry: 1.0
species: 046972
type: SpeciesReference

132798
stoichiometry: 1.0
species: 021291
type: SpeciesReference

932269
product: 129609
reversible: false
type: Reaction
notes: R_CHLPCTD subsystem: Glycerophospholipid Metabolism R_CHLPCTD equation: [c] : cholp + ctp + h --> cdpchol + ppi R_CPCTDTX subsystem: Glycerophospholipid Metabolism R_CPCTDTX equation: [c] : ctp + h + ntm2amep --> cmpntm2amep + ppi
is: http://identifiers.org/ec-code/2.7.7.15
reactant: 129573
fast: false
product: 129597
reactant: 129585
reactant: 129548
is: ENSMMUG00000022675.2
reactant: 129560
is: ENSMMUG00000012821.2
product: 129621

116014
stoichiometry: 10.0
species: 024010
type: SpeciesReference

136807
stoichiometry: 1.0
species: 043295
type: SpeciesReference

092088
stoichiometry: 1.0
species: 041150
type: SpeciesReference

103837
stoichiometry: 1.0
species: 039595
type: SpeciesReference

075689
stoichiometry: 1.0
species: 025541
type: SpeciesReference

020179
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3,4-Dihydroxymandelaldehyde_C8H8O4
type: Species

111921
stoichiometry: 1.0
species: 047081
type: SpeciesReference

038068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

058977
stoichiometry: 1.0
species: 025239
type: SpeciesReference

060493
stoichiometry: 2.0
species: 047033
type: SpeciesReference

027870
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 2_C37H53NO44S4
type: Species

053327
stoichiometry: 1.0
species: 035073
type: SpeciesReference

049261
stoichiometry: 2.0
species: 034363
type: SpeciesReference

094282
stoichiometry: 2.0
species: 027097
type: SpeciesReference

128826
stoichiometry: 2.0
species: 034363
type: SpeciesReference

042379
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S
type: Species

122183
stoichiometry: 1.0
species: 040198
type: SpeciesReference

095992
stoichiometry: 1.0
species: 046343
type: SpeciesReference

090479
stoichiometry: 1.0
species: 038309
type: SpeciesReference

047863
stoichiometry: 1.0
species: 035762
type: SpeciesReference

925636
modifier: 067098
reversible: false
modifier: 067086
reactant: 066714
product: 066870
reactant: 066702
notes: R_SERGLYexR subsystem: Transport, Extracellular R_SERGLYexR equation: gly[c] + ser-L[e] <==> gly[e] + ser-L[c] R_THRGLNexR subsystem: Transport, Extracellular R_THRGLNexR equation: gln-L[c] + thr-L[e] <==> gln-L[e] + thr-L[c] R_ALAGLYexR subsystem: Transport, Extracellular R_ALAGLYexR equation: ala-L[e] + gly[c] <==> ala-L[c] + gly[e] R_SERGLNexR subsystem: Transport, Extracellular R_SERGLNexR equation: gln-L[c] + ser-L[e] <==> gln-L[e] + ser-L[c] R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_AMY1e subsystem: Starch and Sucrose Metabolism R_AMY1e equation: [e] : (8) h2o + strch1 --> (8) glc-D + strch2 R_CYSTGLUex subsystem: Transport, Extracellular R_CYSTGLUex equation: Lcystin[e] + glu-L[c] --> Lcystin[c] + glu-L[e] R_THRGLYexR subsystem: Transport, Extracellular R_THRGLYexR equation: gly[c] + thr-L[e] <==> gly[e] + thr-L[c] R_METLEUex subsystem: Transport, Extracellular R_METLEUex equation: leu-L[c] + met-L[e] --> leu-L[e] + met-L[c] R_ALADGLNexR subsystem: Transport, Extracellular R_ALADGLNexR equation: ala-D[e] + gln-L[c] <==> ala-D[c] + gln-L[e] R_CYSGLYex subsystem: Transport, Extracellular R_CYSGLYex equation: cys-L[c] + gly[e] --> cys-L[e] + gly[c] R_AMY2e subsystem: Starch and Sucrose Metabolism R_AMY2e equation: [e] : glygn2 + (8) h2o --> (8) glc-D + glygn4 R_CYSGLUexR subsystem: Transport, Extracellular R_CYSGLUexR equation: cys-L[e] + gln-L[c] <==> cys-L[c] + gln-L[e] R_SERDGLNexR subsystem: Transport, Extracellular R_SERDGLNexR equation: gln-L[c] + ser-D[e] <==> gln-L[e] + ser-D[c] R_ALADGLYexR subsystem: Transport, Extracellular R_ALADGLYexR equation: ala-D[e] + gly[c] <==> ala-D[c] + gly[e] R_SERDGLYexR subsystem: Transport, Extracellular R_SERDGLYexR equation: gly[c] + ser-D[e] <==> gly[e] + ser-D[c] R_ALAGLNexR subsystem: Transport, Extracellular R_ALAGLNexR equation: ala-L[e] + gln-L[c] <==> ala-L[c] + gln-L[e] R_ARGLYSex subsystem: Transport, Extracellular R_ARGLYSex equation: arg-L[e] + ly…
product: 066786
is: http://identifiers.org/ec-code/3.2.1.1
type: Reaction
reactant: 066690
reactant: 066750
reactant: 066642
product: 066918
reactant: 066738
reactant: 066630
product: 066822
reactant: 066726
modifier: 066954
modifier: 067014
modifier: 067050
product: 066882
product: 066834
modifier: 066942
modifier: 067002
reactant: 066774
product: 066894
modifier: 067038
reactant: 066762
modifier: 067026
reactant: 066678
modifier: 067123
reactant: 066666
product: 066846
reactant: 066654
modifier: 067110
product: 066906
modifier: 066990
is: ENSMMUG00000020354.2
fast: false
product: 066810
product: 066798
modifier: 066978
product: 066930
modifier: 067074
product: 066858
modifier: 066966
modifier: 067062

926633
notes: R_THMt3 subsystem: Transport, Extracellular R_THMt3 equation: h[c] + thm[e] <==> h[e] + thm[c]
reactant: 075120
type: Reaction
reversible: true
product: 075145
product: 075133
name: Thiamine transport in via proton antiport
fast: false
reactant: 075108
is: ENSMMUG00000001508.2

099549
stoichiometry: 1.0
species: 032972
type: SpeciesReference

054521
stoichiometry: 1.0
species: 046235
type: SpeciesReference

928542
type: Reaction
is: ENSMMUG00000008462.2
notes: R_ETHAK subsystem: Glycerophospholipid Metabolism R_ETHAK equation: [c] : atp + etha --> adp + ethamp + h
reactant: 094101
product: 094149
product: 094125
name: Ethanolamine kinase
reactant: 094113
is: ENSMMUG00000006643.2
fast: false
is: http://identifiers.org/ec-code/2.7.1.82
product: 094137
reversible: false

138736
stoichiometry: 1.0
species: 024010
type: SpeciesReference

105367
stoichiometry: 1.0
species: 039619
type: SpeciesReference

125821
stoichiometry: 1.0
species: 027602
type: SpeciesReference

074002
stoichiometry: 1.0
species: 040198
type: SpeciesReference

064609
stoichiometry: 1.0
species: 039020
type: SpeciesReference

114105
stoichiometry: 24.0
species: 034387
type: SpeciesReference

150800
stoichiometry: 3.0
species: 024646
type: SpeciesReference

132919
stoichiometry: 1.0
species: 032753
type: SpeciesReference

067631
stoichiometry: 1.0
species: 040246
type: SpeciesReference

923980
product: 051420
reactant: 051348
product: 051396
reactant: 051336
reversible: false
reactant: 051324
product: 051408
product: 051372
is: http://identifiers.org/ec-code/2.4.99.4
product: 051384
type: Reaction
is: ENSMMUG00000012531.2
reactant: 051360
fast: false
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_S23Tg subsystem: O-Glycan Biosynthesis R_S23Tg equation: [g] : T_antigen + cmpacna --> cmp + h + sT_antigen R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1

026602
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
type: Species

083627
stoichiometry: 1.0
species: 029547
type: SpeciesReference

113778
stoichiometry: 1.0
species: 031363
type: SpeciesReference

103523
stoichiometry: 2.0
species: 040150
type: SpeciesReference

039873
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: ((N-acetyl-D-glucosaminyl)2-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C50H83N4O35X
type: Species

924856
is: http://identifiers.org/ec-code/2.5.1.10
notes: R_MI34PP subsystem: Inositol Phosphate Metabolism R_MI34PP equation: [c] : h2o + mi34p --> mi3p-D + pi R_DMATTx subsystem: Cholesterol Metabolism R_DMATTx equation: [x] : dmpp + ipdp --> grdp + ppi R_GRTTx subsystem: Cholesterol Metabolism R_GRTTx equation: [x] : grdp + ipdp --> frdp + ppi
is: ENSMMUG00000023144.2
reactant: 058686
product: 058758
reactant: 058698
is: ENSMMUG00000006496.2
reactant: 058710
is: http://identifiers.org/ec-code/3.1.3.66
reactant: 058662
product: 058722
product: 058734
type: Reaction
fast: false
reactant: 058674
is: ENSMMUG00000003504.1
reversible: false
is: ENSMMUG00000021101.1
is: ENSMMUG00000019889.2
is: http://identifiers.org/ec-code/2.5.1.1
product: 058770
product: 058746

117944
stoichiometry: 1.0
species: 033408
type: SpeciesReference

115929
stoichiometry: 1.0
species: 046211
type: SpeciesReference

022111
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _6-phospho-D-glucono-1,5-lactone_C6H9O9P
type: Species

139677
stoichiometry: 3.0
species: 026844
type: SpeciesReference

028134
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b_C45H64N2O51S5X
type: Species

085349
stoichiometry: 1.0
species: 029398
type: SpeciesReference

055015
stoichiometry: 20.0
species: 034363
type: SpeciesReference

031520
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide_C10H13N4O9P
type: Species

106319
stoichiometry: 1.0
species: 042367
type: SpeciesReference

050251
stoichiometry: 2.0
species: 028764
type: SpeciesReference

066654
stoichiometry: 1.0
species: 028303
type: SpeciesReference

057275
stoichiometry: 1.0
species: 032729
type: SpeciesReference

028436
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Deoxyadenosine_C10H13N5O3
type: Species

098873
stoichiometry: 1.0
species: 044705
type: SpeciesReference

045947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Testosterone_C19H28O2
type: Species

933243
is: ENSMMUG00000003122.2
reactant: 138446
notes: R_CHOLK subsystem: Glycerophospholipid Metabolism R_CHOLK equation: [c] : atp + chol --> adp + cholp + h
type: Reaction
product: 138458
is: http://identifiers.org/ec-code/2.7.1.32
name: Choline kinase
reversible: false
product: 138482
reactant: 138434
fast: false
product: 138470

131967
stoichiometry: 1.0
species: 023526
type: SpeciesReference

029667
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dihomo-gamma-linolenic acid (n-6)_C20H33O2
type: Species

120477
stoichiometry: 1.0
species: 039595
type: SpeciesReference

082673
stoichiometry: 1.0
species: 025541
type: SpeciesReference

145030
stoichiometry: 1.0
species: 028026
type: SpeciesReference

032935
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: D-Glucose_C6H12O6
type: Species

033335
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Glycine betaine_C5H11NO2
type: Species

146275
stoichiometry: 2.0
species: 023162
type: SpeciesReference

109345
stoichiometry: 2.0
species: 024010
type: SpeciesReference

121860
stoichiometry: 1.0
species: 027302
type: SpeciesReference

076060
stoichiometry: 2.0
species: 042355
type: SpeciesReference

032160
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GA2 (homo sapiens)_C38H69N2O17FULLRCO
type: Species

085975
stoichiometry: 1.0
species: 034412
type: SpeciesReference

037365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 3_C47H76N4O33X
type: Species

101903
stoichiometry: 1.0
species: 020228
type: SpeciesReference

931037
type: Reaction
is: ENSMMUG00000005959.2
is: ENSMMUG00000011292.2
is: ENSMMUG00000020782.2
product: 117968
reversible: false
reactant: 117944
fast: false
notes: R_GLYKm subsystem: Glycerophospholipid Metabolism R_GLYKm equation: [m] : atp + glyc --> adp + glyc3p + h R_GLYK subsystem: Glycerophospholipid Metabolism R_GLYK equation: [c] : atp + glyc --> adp + glyc3p + h
is: http://identifiers.org/ec-code/2.7.1.30
reactant: 117908
product: 117956
reactant: 117920
product: 117992
reactant: 117932
product: 117980
product: 118016
product: 118004

111813
stoichiometry: 6.0
species: 034412
type: SpeciesReference

930337
product: 110113
reactant: 110065
reactant: 110077
type: Reaction
product: 110101
product: 110089
fast: false
reversible: false
reactant: 110040
reactant: 110053
is: ENSMMUG00000020213.2
notes: R_AKR1D2 subsystem: Bile Acid Biosynthesis R_AKR1D2 equation: [c] : h + nadph + xoldiolone --> nadp + xoldioloneh R_AKR1D subsystem: Bile Acid Biosynthesis R_AKR1D equation: [c] : h + nadph + xol7aone --> nadp + xol7ah

087679
stoichiometry: 1.0
species: 028231
type: SpeciesReference

043079
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Prostaglandin E1_C20H33O5
type: Species

137145
stoichiometry: 111.0
species: 034412
type: SpeciesReference

126387
stoichiometry: 1.0
species: 031484
type: SpeciesReference

066594
stoichiometry: 1.0
species: 030394
type: SpeciesReference

041982
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Phenethylamine_C8H12N
type: Species

148433
stoichiometry: 1.0
species: 023950
type: SpeciesReference

119244
stoichiometry: 1.0
species: 032221
type: SpeciesReference

025445
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Asparagine_C4H8N2O3
type: Species

114767
stoichiometry: 1.0
species: 036703
type: SpeciesReference

091510
stoichiometry: 1.0
species: 042524
type: SpeciesReference

141342
stoichiometry: 1.0
species: 034253
type: SpeciesReference

133857
stoichiometry: 1.0
species: 034472
type: SpeciesReference

048814
stoichiometry: 1.0
species: 040077
type: SpeciesReference

072706
stoichiometry: 1.0
species: 023066
type: SpeciesReference

128401
stoichiometry: 1.0
species: 043777
type: SpeciesReference

135529
stoichiometry: 1.0
species: 035350
type: SpeciesReference

928830
reactant: 096187
reactant: 096200
product: 096212
product: 096225
reversible: false
name: phosphopantothenoylcysteine decarboxylase
notes: R_PPCDC subsystem: CoA Biosynthesis R_PPCDC equation: [c] : 4ppcys + h --> co2 + pan4p
is: ENSMMUG00000018801.1
is: http://identifiers.org/ec-code/4.1.1.36
type: Reaction
fast: false

117522
stoichiometry: 1.0
species: 044210
type: SpeciesReference

062548
stoichiometry: 1.0
species: 040789
type: SpeciesReference

022644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: R total 2 coenzyme A_CO2FULLR2C21H31N7O15P3S
type: Species

126869
stoichiometry: 1.0
species: 032160
type: SpeciesReference

051096
stoichiometry: 2.0
species: 039377
type: SpeciesReference

111065
stoichiometry: 1.0
species: 028848
type: SpeciesReference

W3 CDTF: Fri Feb 03 12:35:00 GMT 2012

020702
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3-Methyl-2-oxobutanoate_C5H7O3
type: Species

123578
stoichiometry: 3.0
species: 040450
type: SpeciesReference

110330
stoichiometry: 1.0
species: 041934
type: SpeciesReference

933099
is: ENSMMUG00000010575.2
name: succinate dehydrogenase
is: ENSMMUG00000014452.2
fast: false
product: 137713
reversible: true
is: ENSMMUG00000009488.2
reactant: 137688
reactant: 137676
is: ENSMMUG00000030925.1
is: ENSMMUG00000001614.2
type: Reaction
is: ENSMMUG00000015247.2
is: http://identifiers.org/ec-code/1.3.99.1
product: 137701
is: ENSMMUG00000000346.2
notes: R_SUCD1m subsystem: Citric Acid Cycle R_SUCD1m equation: [m] : fad + succ <==> fadh2 + fum
is: ENSMMUG00000012411.2

062693
stoichiometry: 1.0
species: 034253
type: SpeciesReference

099271
stoichiometry: 5.0
species: 034363
type: SpeciesReference

060095
stoichiometry: 2.0
species: 025541
type: SpeciesReference

040065
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Nicotinate_C6H4NO2
type: Species

096064
stoichiometry: 1.0
species: 042548
type: SpeciesReference

136903
stoichiometry: 2.0
species: 028752
type: SpeciesReference

056599
stoichiometry: 2.0
species: 034363
type: SpeciesReference

074831
stoichiometry: 3.0
species: 034253
type: SpeciesReference

137424
stoichiometry: 3.0
species: 040813
type: SpeciesReference

087377
stoichiometry: 2.0
species: 040282
type: SpeciesReference

043295
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S
type: Species

092378
stoichiometry: 1.0
species: 024226
type: SpeciesReference

070177
stoichiometry: 1.0
species: 024501
type: SpeciesReference

933544
product: 141692
reversible: true
reactant: 141668
fast: false
product: 141680
reactant: 141656
type: Reaction
name: phosphate transport in/out via three Na+ symporter
is: ENSMMUG00000021135.2
is: ENSMMUG00000019814.2
notes: R_PIt7 subsystem: Transport, Extracellular R_PIt7 equation: (3) na1[e] + pi[e] <==> (3) na1[c] + pi[c]

W3 CDTF: Fri Feb 03 12:35:00 GMT 2012

148770
stoichiometry: 1.0
species: 020131
type: SpeciesReference

142029
stoichiometry: 1.0
species: 029424
type: SpeciesReference

924016
is: ENSMMUG00000002579.2
fast: false
type: Reaction
reactant: 051612
is: ENSMMUG00000007110.1
is: ENSMMUG00000002586.2
is: ENSMMUG00000004701.1
product: 051637
is: ENSMMUG00000016494.2
is: ENSMMUG00000002582.2
reversible: false
name: phosphate transport in/out via three Na+ symporter (irreversible)
product: 051624
notes: R_PIt7ir subsystem: Transport, Extracellular R_PIt7ir equation: (3) na1[e] + pi[e] --> (3) na1[c] + pi[c]
reactant: 051600

093450
stoichiometry: 2.0
species: 034363
type: SpeciesReference

032076
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1960H3228N20O770P20
type: Species

088318
stoichiometry: 2.0
species: 027073
type: SpeciesReference

145601
stoichiometry: 2.0
species: 027614
type: SpeciesReference

024010
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: ADP_C10H12N5O10P2
type: Species

131546
stoichiometry: 1.0
species: 033604
type: SpeciesReference

027494
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Cortisol_C21H30O5
type: Species

134026
stoichiometry: 2.0
species: 034363
type: SpeciesReference

107992
stoichiometry: 3.0
species: 028534
type: SpeciesReference

093306
stoichiometry: 1.0
species: 028146
type: SpeciesReference

061874
stoichiometry: 1.0
species: 024275
type: SpeciesReference

134808
stoichiometry: 1.0
species: 041295
type: SpeciesReference

118726
stoichiometry: 3.0
species: 024046
type: SpeciesReference

077581
stoichiometry: 1.0
species: 024792
type: SpeciesReference

W3 CDTF: Thu Aug 12 17:06:23 BST 2010

127753
stoichiometry: 2.0
species: 040198
type: SpeciesReference

032597
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Glycolaldehyde_C2H4O2
type: Species

131690
stoichiometry: 1.0
species: 036992
type: SpeciesReference

075387
stoichiometry: 1.0
species: 047417
type: SpeciesReference

064561
stoichiometry: 1.0
species: 039032
type: SpeciesReference

052471
stoichiometry: 1.0
species: 036161
type: SpeciesReference

022909
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (S)-Squalene-2,3-epoxide_C30H50O
type: Species

065849
stoichiometry: 1.0
species: 039475
type: SpeciesReference

023090
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Acetate_C2H3O2
type: Species

042668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Protoporphyrinogen IX_C34H38N4O4
type: Species

129152
stoichiometry: 1.0
species: 031351
type: SpeciesReference

076459
stoichiometry: 2.0
species: 034363
type: SpeciesReference

933808
notes: R_SERGLYexR subsystem: Transport, Extracellular R_SERGLYexR equation: gly[c] + ser-L[e] <==> gly[e] + ser-L[c] R_THRGLNexR subsystem: Transport, Extracellular R_THRGLNexR equation: gln-L[c] + thr-L[e] <==> gln-L[e] + thr-L[c] R_ALAGLYexR subsystem: Transport, Extracellular R_ALAGLYexR equation: ala-L[e] + gly[c] <==> ala-L[c] + gly[e] R_SERGLNexR subsystem: Transport, Extracellular R_SERGLNexR equation: gln-L[c] + ser-L[e] <==> gln-L[e] + ser-L[c] R_THRGLYexR subsystem: Transport, Extracellular R_THRGLYexR equation: gly[c] + thr-L[e] <==> gly[e] + thr-L[c] R_ALADGLNexR subsystem: Transport, Extracellular R_ALADGLNexR equation: ala-D[e] + gln-L[c] <==> ala-D[c] + gln-L[e] R_CYSGLUexR subsystem: Transport, Extracellular R_CYSGLUexR equation: cys-L[e] + gln-L[c] <==> cys-L[c] + gln-L[e] R_SERDGLNexR subsystem: Transport, Extracellular R_SERDGLNexR equation: gln-L[c] + ser-D[e] <==> gln-L[e] + ser-D[c] R_ALADGLYexR subsystem: Transport, Extracellular R_ALADGLYexR equation: ala-D[e] + gly[c] <==> ala-D[c] + gly[e] R_SERDGLYexR subsystem: Transport, Extracellular R_SERDGLYexR equation: gly[c] + ser-D[e] <==> gly[e] + ser-D[c] R_ALAGLNexR subsystem: Transport, Extracellular R_ALAGLNexR equation: ala-L[e] + gln-L[c] <==> ala-L[c] + gln-L[e] R_CYSGLYexR subsystem: Transport, Extracellular R_CYSGLYexR equation: cys-L[c] + gly[e] <==> cys-L[e] + gly[c]
fast: false
type: Reaction
reactant: 144077
product: 144197
reactant: 144005
product: 144173
reversible: true
product: 144125
product: 144233
product: 144221
reactant: 144065
product: 144185
reactant: 144041
reactant: 144113
reactant: 144053
product: 144161
reactant: 144029
reactant: 144101
is: ENSMMUG00000022875.2
product: 144209
product: 144149
reactant: 144017
product: 144137
reactant: 144089

085854
stoichiometry: 2.0
species: 042956
type: SpeciesReference

110547
stoichiometry: 4.0
species: 040029
type: SpeciesReference

073335
stoichiometry: 1.0
species: 042896
type: SpeciesReference

101747
stoichiometry: 1.0
species: 026662
type: SpeciesReference

063212
stoichiometry: 1.0
species: 041356
type: SpeciesReference

133305
stoichiometry: 30.0
species: 040198
type: SpeciesReference

138518
stoichiometry: 1.0
species: 040522
type: SpeciesReference

095800
stoichiometry: 1.0
species: 044778
type: SpeciesReference

023731
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-Acetylneuraminate_C11H18NO9
type: Species

067415
stoichiometry: 1.0
species: 032657
type: SpeciesReference

930557
is: http://identifiers.org/ec-code/3.5.4.9
type: Reaction
is: http://identifiers.org/ec-code/1.5.1.5
product: 112308
reactant: 112212
reactant: 112248
notes: R_MTHFDm subsystem: Folate Metabolism R_MTHFDm equation: [m] : mlthf + nadp <==> methf + nadph R_FTHFLm subsystem: Folate Metabolism R_FTHFLm equation: [m] : atp + for + thf <==> 10fthf + adp + pi R_MTHFCm subsystem: Folate Metabolism R_MTHFCm equation: [m] : h2o + methf <==> 10fthf + h
product: 112296
product: 112284
is: ENSMMUG00000019774.2
reactant: 112188
product: 112272
product: 112260
product: 112320
is: http://identifiers.org/ec-code/6.3.4.3
reactant: 112200
reactant: 112224
reactant: 112236
fast: false
reactant: 112176
is: ENSMMUG00000007137.2
reversible: true

020337
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3,5-Diiodo-L-tyrosine_C9H9I2NO3
type: Species

022364
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-2-Aminoadipate_C6H10NO4
type: Species

124857
stoichiometry: 1.0
species: 034253
type: SpeciesReference

125037
stoichiometry: 1.0
species: 032136
type: SpeciesReference

104800
stoichiometry: 1.0
species: 027554
type: SpeciesReference

136265
stoichiometry: 1.0
species: 034253
type: SpeciesReference

042824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Progesterone_C21H30O2
type: Species

057383
stoichiometry: 1.0
species: 022897
type: SpeciesReference

926201
fast: false
is: ENSMMUG00000012165.2
reactant: 071523
reversible: true
reactant: 071535
product: 071559
name: phosphate transport in/out via two Na+ symporter
notes: R_PIt9 subsystem: Transport, Extracellular R_PIt9 equation: (2) na1[e] + pi[e] <==> (2) na1[c] + pi[c]
product: 071547
type: Reaction

085638
stoichiometry: 3.0
species: 041754
type: SpeciesReference

930634
product: 113296
reactant: 113127
reactant: 113103
is: ENSMMUG00000008336.2
reactant: 113187
reactant: 113175
reactant: 113151
product: 113356
fast: false
reactant: 113223
type: Reaction
product: 113320
product: 113260
reactant: 113211
is: http://identifiers.org/ec-code/1.2.1.3
reactant: 113199
product: 113368
product: 113247
product: 113344
product: 113284
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_BAMPPALDOXm subsystem: beta-Alanine metabolism R_BAMPPALDOXm equation: [m] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_ALDD2xm subsystem: Glycolysis/Gluconeogenesis R_ALDD2xm equation: [m] : acald + h2o + nad --> ac + (2) h + nadh R_NABTNOm subsystem: Arginine and Proline Metabolism R_NABTNOm equation: [m] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_PYLALDOXm subsystem: Limonene and pinene degradation R_PYLALDOXm equation: [m] : h2o + nad + pylald --> (2) h + nadh + peracd R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD_m subsystem: Histidine Metabolism R_IMACTD_m equation: [m] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD20xm subsystem: Tryptophan metabolism R_ALDD20xm equation: [m] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_5HOXINDACTOXm subsystem: Tryptophan metabolism R_5HOXINDACTOXm equation: [m] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_GLACOm subsystem: Ascorbate and Aldarate Metabolism R_GLACOm equation: [m] : glac + (2) h2o + nad --> glcr + (3) h + nadh
reversible: false
reactant: 113091
reactant: 113079
product: 113380
is: http://identifiers.org/ec-code/1.2.1.21
is: ENSMMUG00000013057.1
product: 113272
product: 113308
reactant: 113163
product: 113235
product: 113332
reactant: 113139
reactant: 113115

033009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: D-Glucuronate_C6H9O7
type: Species

054942
stoichiometry: 4.0
species: 039020
type: SpeciesReference

144643
stoichiometry: 1.0
species: 044681
type: SpeciesReference

148129
stoichiometry: 1.0
species: 032621
type: SpeciesReference

026287
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: CDP_C9H12N3O11P2
type: Species

923836
reactant: 049768
is: ENSMMUG00000022409.2
reactant: 049743
notes: R_TCHOLAt2 subsystem: Transport, Extracellular R_TCHOLAt2 equation: (2) na1[e] + tchola[e] --> (2) na1[c] + tchola[c] R_ESTRONESt2 subsystem: Transport, Extracellular R_ESTRONESt2 equation: estrones[e] + (2) na1[e] --> estrones[c] + (2) na1[c] R_CHOLATEt2 subsystem: Transport, Extracellular R_CHOLATEt2 equation: cholate[e] + (2) na1[e] --> cholate[c] + (2) na1[c] R_GCHOLAt2 subsystem: Transport, Extracellular R_GCHOLAt2 equation: gchola[e] + (2) na1[e] --> gchola[c] + (2) na1[c]
fast: false
product: 049828
product: 049816
reversible: false
reactant: 049756
product: 049804
product: 049852
product: 049840
reactant: 049792
reactant: 049780
type: Reaction

067813
stoichiometry: 1.0
species: 044947
type: SpeciesReference

932161
reactant: 128607
type: Reaction
is: http://identifiers.org/ec-code/2.5.1.10
is: http://identifiers.org/ec-code/2.5.1.29
reactant: 128570
reversible: false
product: 128680
reactant: 128582
product: 128656
is: ENSMMUG00000007145.2
is: http://identifiers.org/ec-code/2.5.1.1
product: 128619
product: 128631
is: http://identifiers.org/ec-code/2.4.1.155
product: 128644
reactant: 128595
reactant: 128546
product: 128692
reactant: 128558
fast: false
product: 128668
notes: R_DMATT subsystem: Cholesterol Metabolism R_DMATT equation: [c] : dmpp + ipdp --> grdp + ppi R_FRTT subsystem: Cholesterol Metabolism R_FRTT equation: [c] : frdp + ipdp --> ggdp + ppi R_M16N6Tg subsystem: N-Glycan Biosynthesis R_M16N6Tg equation: [g] : n3m2masn + uacgam --> h + n4m2masn + udp R_GRTT subsystem: Cholesterol Metabolism R_GRTT equation: [c] : grdp + ipdp --> frdp + ppi

116873
stoichiometry: 1.0
species: 039800
type: SpeciesReference

108330
stoichiometry: 1.0
species: 036101
type: SpeciesReference

106283
stoichiometry: 1.0
species: 021690
type: SpeciesReference

083085
stoichiometry: 1.0
species: 034363
type: SpeciesReference

146986
stoichiometry: 8.0
species: 034363
type: SpeciesReference

128753
stoichiometry: 2.0
species: 025541
type: SpeciesReference

146829
stoichiometry: 5.0
species: 034253
type: SpeciesReference

093522
stoichiometry: 1.0
species: 044621
type: SpeciesReference

033119
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Glutamate_C5H8NO4
type: Species

071547
stoichiometry: 1.0
species: 042283
type: SpeciesReference

116232
stoichiometry: 1.0
species: 030078
type: SpeciesReference

143693
stoichiometry: 1.0
species: 041681
type: SpeciesReference

096915
stoichiometry: 4.0
species: 034448
type: SpeciesReference

094826
stoichiometry: 1.0
species: 034253
type: SpeciesReference

092907
stoichiometry: 6.0
species: 028812
type: SpeciesReference

932594
reactant: 133464
reactant: 133428
type: Reaction
notes: R_SR5ARr subsystem: Steroid Metabolism R_SR5ARr equation: [r] : h + nadph + tststerone --> 5adtststerone + nadp R_SR5AR2r subsystem: Steroid Metabolism R_SR5AR2r equation: [r] : andrstndn + h + nadph --> andrstandn + nadp
product: 133476
reactant: 133452
reversible: false
product: 133488
is: http://identifiers.org/ec-code/1.3.99.5
reactant: 133440
product: 133500
is: ENSMMUG00000013186.1
fast: false

060662
stoichiometry: 4.0
species: 024010
type: SpeciesReference

090696
stoichiometry: 1.0
species: 025300
type: SpeciesReference

084023
stoichiometry: 1.0
species: 029151
type: SpeciesReference

051637
stoichiometry: 3.0
species: 040017
type: SpeciesReference

083843
stoichiometry: 1.0
species: 029054
type: SpeciesReference

147659
stoichiometry: 1.0
species: 030722
type: SpeciesReference

049961
stoichiometry: 1.0
species: 028098
type: SpeciesReference

035471
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 15_C79H114N5O98S11X
type: Species

134964
stoichiometry: 1.0
species: 023974
type: SpeciesReference

089307
stoichiometry: 1.0
species: 037028
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name: de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)_C54H91N3O41
type: Species

061166
stoichiometry: 1.0
species: 044560
type: SpeciesReference

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stoichiometry: 1.0
species: 045633
type: SpeciesReference

058542
stoichiometry: 1.0
species: 040789
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126797
stoichiometry: 4.0
species: 046307
type: SpeciesReference

W3 CDTF: Fri Feb 03 12:35:00 GMT 2012

039703
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _5,10-Methylenetetrahydrofolate_C20H21N7O6
type: Species

152162
stoichiometry: 1.0
species: 021895
type: SpeciesReference

044113
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Selenide_HSe
type: Species

089452
stoichiometry: 1.0
species: 037414
type: SpeciesReference

021111
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _4-Aminobutanoate_C4H9NO2
type: Species

927882
product: 086338
reactant: 086290
is: http://identifiers.org/ec-code/2.4.99.3
type: Reaction
reversible: false
product: 086350
product: 086362
reactant: 086302
notes: R_NS26T2g subsystem: O-Glycan Biosynthesis R_NS26T2g equation: [g] : cmpacna + sT_antigen --> cmp + dsT_antigen + h R_NS26Tg subsystem: O-Glycan Biosynthesis R_NS26Tg equation: [g] : Tn_antigen + cmpacna --> cmp + h + sTn_antigen
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fast: false
product: 086326
reactant: 086314

086701
stoichiometry: 1.0
species: 038803
type: SpeciesReference

049816
stoichiometry: 1.0
species: 026506
type: SpeciesReference

112418
stoichiometry: 1.0
species: 020690
type: SpeciesReference

092594
stoichiometry: 1.0
species: 046803
type: SpeciesReference

098656
stoichiometry: 1.0
species: 025239
type: SpeciesReference

055356
stoichiometry: 1.0
species: 027374
type: SpeciesReference

066438
stoichiometry: 1.0
species: 022607
type: SpeciesReference

046355
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: UDPglucose_C15H22N2O17P2
type: Species

090019
stoichiometry: 1.0
species: 019731
type: SpeciesReference

027650
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 5_C23H36O24S
type: Species

132377
stoichiometry: 1.0
species: 034387
type: SpeciesReference

118185
stoichiometry: 1.0
species: 032016
type: SpeciesReference

082516
stoichiometry: 10.0
species: 024034
type: SpeciesReference

120898
stoichiometry: 1.0
species: 032923
type: SpeciesReference

123241
stoichiometry: 1.0
species: 041369
type: SpeciesReference

095271
stoichiometry: 1.0
species: 027181
type: SpeciesReference

079358
stoichiometry: 1.0
species: 025445
type: SpeciesReference

032717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO
type: Species

929927
reactant: 105812
fast: false
product: 105848
product: 105872
reactant: 105824
product: 105836
reversible: true
type: Reaction
notes: R_CERT2rt subsystem: Transport, Endoplasmic Reticular R_CERT2rt equation: gluside_hs[c] <==> gluside_hs[r] R_CERT1gt subsystem: Transport, Golgi Apparatus R_CERT1gt equation: crm_hs[c] <==> crm_hs[g] R_CERT2gt subsystem: Transport, Golgi Apparatus R_CERT2gt equation: gluside_hs[c] <==> gluside_hs[g] R_CERT1rt subsystem: Transport, Endoplasmic Reticular R_CERT1rt equation: crm_hs[c] <==> crm_hs[r]
is: ENSMMUG00000006141.2
product: 105860

052990
stoichiometry: 1.0
species: 041549
type: SpeciesReference

069103
stoichiometry: 2.0
species: 034387
type: SpeciesReference

W3 CDTF: Fri Feb 03 12:35:00 GMT 2012

143140
stoichiometry: 1.0
species: 036413
type: SpeciesReference

082891
stoichiometry: 1.0
species: 034363
type: SpeciesReference

082008
stoichiometry: 1.0
species: 043091
type: SpeciesReference

103305
stoichiometry: 1.0
species: 028692
type: SpeciesReference

116474
stoichiometry: 1.0
species: 046525
type: SpeciesReference

137362
stoichiometry: 1.0
species: 031169
type: SpeciesReference

088642
stoichiometry: 1.0
species: 042283
type: SpeciesReference

061910
stoichiometry: 2.0
species: 034363
type: SpeciesReference

072926
stoichiometry: 1.0
species: 044005
type: SpeciesReference

095667
stoichiometry: 1.0
species: 026820
type: SpeciesReference

112296
stoichiometry: 2.0
species: 019421
type: SpeciesReference

031303
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Fe2+_Fe
type: Species

067969
stoichiometry: 1.0
species: 046283
type: SpeciesReference

025661
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: cis-beta-D-Glucosyl-2-hydroxycinnamate_C15H18O8
type: Species

027169
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: Coenzyme A_C21H32N7O16P3S
type: Species

114323
stoichiometry: 2.0
species: 034363
type: SpeciesReference

091968
stoichiometry: 1.0
species: 022632
type: SpeciesReference

051312
stoichiometry: 2.0
species: 040162
type: SpeciesReference

057071
stoichiometry: 2.0
species: 026977
type: SpeciesReference

038754
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

077364
stoichiometry: 1.0
species: 025637
type: SpeciesReference

089874
stoichiometry: 1.0
species: 039728
type: SpeciesReference

932305
reactant: 129910
modifier: 129995
modifier: 129983
reversible: false
modifier: 129971
product: 129946
notes: R_THMt3 subsystem: Transport, Extracellular R_THMt3 equation: h[c] + thm[e] <==> h[e] + thm[c] R_BTNt4i subsystem: Transport, Extracellular R_BTNt4i equation: btn[e] + h[c] --> btn[c] + h[e]
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fast: false
modifier: 129959
product: 129934
reactant: 129922
type: Reaction

025987
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Butyrate (n-C4:0)_C4H7O2
type: Species

924568
reversible: false
type: Reaction
product: 056660
product: 056648
is: http://identifiers.org/ec-code/2.4.1.79
product: 056672
notes: R_B3GALT3g subsystem: Sphingolipid Metabolism R_B3GALT3g equation: [g] : thcrm_hs + udpacgal --> gbside_hs + h + udp
reactant: 056636
name: Beta-1,3-galactosyltransferase 3
fast: false
reactant: 056623
is: ENSMMUG00000003541.2

087823
stoichiometry: 1.0
species: 034339
type: SpeciesReference

926093
reversible: false
fast: false
product: 070743
is: ENSMMUG00000023608.2
is: ENSMMUG00000011486.2
is: ENSMMUG00000017370.2
is: ENSMMUG00000004408.2
is: ENSMMUG00000022784.2
product: 070755
reactant: 070731
notes: R_PLYSPSer subsystem: Lysine Metabolism R_PLYSPSer equation: [r] : Ntmelys + h2o --> pepslys + tmlys
reactant: 070719
is: ENSMMUG00000018959.2
type: Reaction
is: ENSMMUG00000010685.2
name: protein lysine peptidase (endoplasmic reticulum)

023610
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
type: Species

933976
is: ENSMMUG00000008417.2
type: Reaction
reactant: 147515
is: ENSMMUG00000014705.2
reactant: 147491
is: http://identifiers.org/ec-code/1.10.2.2
notes: R_CYOR_DASH_u10m subsystem: Oxidative Phosphorylation R_CYOR_DASH_u10m equation: (2) ficytC[m] + (2) h[m] + q10h2[m] --> (2) focytC[m] + (4) h[c] + q10[m]
is: ENSMMUG00000011495.2
reactant: 147503
is: ENSMMUG00000030221.1
is: ENSMMUG00000015635.2
name: ubiquinol-6 cytochrome c reductase, Complex III
is: ENSMMUG00000018287.2
is: ENSMMUG00000023048.1
product: 147539
is: ENSMMUG00000028670.1
is: ENSMMUG00000009016.2
is: ENSMMUG00000030152.1
is: ENSMMUG00000031090.1
is: ENSMMUG00000007149.1
reversible: false
is: ENSMMUG00000008804.2
product: 147527
is: ENSMMUG00000004204.2
product: 147551
fast: false

081467
stoichiometry: 1.0
species: 035860
type: SpeciesReference

050685
stoichiometry: 1.0
species: 031956
type: SpeciesReference

061718
stoichiometry: 1.0
species: 023235
type: SpeciesReference

086011
stoichiometry: 1.0
species: 023235
type: SpeciesReference

930409
is: ENSMMUG00000001498.2
type: Reaction
reactant: 110752
product: 110776
reactant: 110716
product: 110764
product: 110788
notes: R_DCYTD subsystem: Pyrimidine Catabolism R_DCYTD equation: [c] : dcyt + h + h2o --> duri + nh4 R_CYTD subsystem: Pyrimidine Catabolism R_CYTD equation: [c] : cytd + h + h2o --> nh4 + uri
reactant: 110740
is: http://identifiers.org/ec-code/3.5.4.5
reactant: 110728
reversible: false
is: http://identifiers.org/ec-code/3.5.4.14
fast: false

090997
stoichiometry: 1.0
species: 040282
type: SpeciesReference

079130
stoichiometry: 1.0
species: 024792
type: SpeciesReference

109129
stoichiometry: 1.0
species: 042055
type: SpeciesReference

046575
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Uracil_C4H4N2O2
type: Species

021558
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8
type: Species

144389
stoichiometry: 1.0
species: 044585
type: SpeciesReference

107811
stoichiometry: 1.0
species: 041850
type: SpeciesReference

115176
stoichiometry: 1.0
species: 036655
type: SpeciesReference

094307
stoichiometry: 1.0
species: 023235
type: SpeciesReference

071111
stoichiometry: 1.0
species: 031750
type: SpeciesReference

141560
stoichiometry: 1.0
species: 026844
type: SpeciesReference

040318
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3
type: Species

927245
reactant: 079914
reactant: 079890
product: 079962
is: ENSMMUG00000012994.2
product: 079974
product: 079950
reactant: 079938
product: 079986
type: Reaction
product: 079998
reactant: 079902
reversible: false
notes: R_C4STMO1r subsystem: Cholesterol Metabolism R_C4STMO1r equation: [r] : 44mzym + (3) h + (3) nadph + (3) o2 --> 4mzym_int1 + (4) h2o + (3) nadp R_C4STMO2r subsystem: Cholesterol Metabolism R_C4STMO2r equation: [r] : 4mzym_int2 + nad + o2 --> co2 + h + nadh + zym_int2
fast: false
product: 080010
reactant: 079878
reactant: 079926
product: 080022

104283
stoichiometry: 1.0
species: 040789
type: SpeciesReference

117740
stoichiometry: 1.0
species: 041657
type: SpeciesReference

042512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Propanoyl-CoA_C24H36N7O17P3S
type: Species

082745
stoichiometry: 1.0
species: 031109
type: SpeciesReference

148215
stoichiometry: 1.0
species: 043259
type: SpeciesReference

110113
stoichiometry: 1.0
species: 047153
type: SpeciesReference

134351
stoichiometry: 1.0
species: 040789
type: SpeciesReference

098188
stoichiometry: 1.0
species: 044533
type: SpeciesReference

133040
stoichiometry: 2.0
species: 040017
type: SpeciesReference

029921
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Dolichol diphosphate, human uterine homolog_C1025H1670O70P20
type: Species

030357
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dUDP_C9H11N2O11P2
type: Species

073482
stoichiometry: 1.0
species: 024214
type: SpeciesReference

074291
stoichiometry: 1.0
species: 026251
type: SpeciesReference

115712
stoichiometry: 2.0
species: 034363
type: SpeciesReference

113031
stoichiometry: 1.0
species: 033481
type: SpeciesReference

136037
stoichiometry: 1.0
species: 044283
type: SpeciesReference

078741
stoichiometry: 1.0
species: 034303
type: SpeciesReference

043331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Putrescine_C4H14N2
type: Species

140931
stoichiometry: 1.0
species: 025975
type: SpeciesReference

931465
fast: false
name: citrate synthase
is: ENSMMUG00000002483.2
reactant: 122316
reactant: 122328
type: Reaction
product: 122376
product: 122364
reversible: false
notes: R_CSm subsystem: Citric Acid Cycle R_CSm equation: [m] : accoa + h2o + oaa --> cit + coa + h
reactant: 122340
product: 122352

139339
stoichiometry: 1.0
species: 033275
type: SpeciesReference

925252
product: 062922
product: 062909
reactant: 062861
is: ENSMMUG00000017651.2
product: 062897
type: Reaction
fast: false
reactant: 062849
reversible: false
is: http://identifiers.org/ec-code/2.8.2.23
reactant: 062873
product: 062885
notes: R_S3T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T1g equation: [g] : hs_pre13 + paps --> h + hs_pre14 + pap R_S3T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T2g equation: [g] : hs_pre14 + paps --> h + hs_pre15 + pap

097900
stoichiometry: 2.0
species: 034315
type: SpeciesReference

040632
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Naphthalene_C10H8
type: Species

074411
stoichiometry: 1.0
species: 034520
type: SpeciesReference

137640
stoichiometry: 1.0
species: 042764
type: SpeciesReference

102036
stoichiometry: 1.0
species: 046199
type: SpeciesReference

096200
stoichiometry: 1.0
species: 034363
type: SpeciesReference

039535
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: _1D-myo-Inositol 1,3,4,6-tetrakisphosphate_C6H8O18P4
type: Species

021847
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Hydroxykynurenine_C10H12N2O4
type: Species

928326
product: 090997
name: malic enzyme (NADP), mitochondrial
reactant: 090949
product: 090985
notes: R_ME2m subsystem: Pyruvate Metabolism R_ME2m equation: [m] : mal-L + nadp --> co2 + nadph + pyr
reversible: false
product: 090973
reactant: 090961
is: http://identifiers.org/ec-code/1.1.1.40
is: ENSMMUG00000013055.2
fast: false
type: Reaction

097083
stoichiometry: 1.0
species: 033082
type: SpeciesReference

144221
stoichiometry: 2.0
species: 024646
type: SpeciesReference

066005
stoichiometry: 1.0
species: 020216
type: SpeciesReference

079069
stoichiometry: 1.0
species: 033082
type: SpeciesReference

135745
stoichiometry: 1.0
species: 041934
type: SpeciesReference

071897
stoichiometry: 2.0
species: 038128
type: SpeciesReference

110764
stoichiometry: 1.0
species: 030418
type: SpeciesReference

097395
stoichiometry: 6.0
species: 040150
type: SpeciesReference

134243
stoichiometry: 1.0
species: 026444
type: SpeciesReference

121211
stoichiometry: 1.0
species: 029909
type: SpeciesReference

100371
stoichiometry: 1.0
species: 042283
type: SpeciesReference

044453
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

146407
stoichiometry: 1.0
species: 020191
type: SpeciesReference

150101
stoichiometry: 1.0
species: 022776
type: SpeciesReference

063911
stoichiometry: 1.0
species: 027205
type: SpeciesReference

111281
stoichiometry: 1.0
species: 027735
type: SpeciesReference

100638
stoichiometry: 1.0
species: 034363
type: SpeciesReference

117090
stoichiometry: 1.0
species: 043103
type: SpeciesReference

113247
stoichiometry: 1.0
species: 033457
type: SpeciesReference

128982
stoichiometry: 2.0
species: 038754
type: SpeciesReference

140304
stoichiometry: 1.0
species: 037414
type: SpeciesReference

128607
stoichiometry: 3.0
species: 036077
type: SpeciesReference

058458
stoichiometry: 1.0
species: 043512
type: SpeciesReference

107100
stoichiometry: 1.0
species: 021038
type: SpeciesReference

928614
reactant: 094717
product: 094729
name: inositol transport via sodium symport
product: 094741
fast: false
reversible: true
notes: R_INSTt4_2 subsystem: Transport, Extracellular R_INSTt4_2 equation: inost[e] + (2) na1[e] <==> inost[c] + (2) na1[c]
reactant: 094705
type: Reaction
is: ENSMMUG00000001407.2

925684
is: ENSMMUG00000001731.2
type: Reaction
is: ENSMMUG00000013797.2
reactant: 067329
is: http://identifiers.org/ec-code/2.6.1.16
product: 067353
notes: R_GF6PTA subsystem: Aminosugar Metabolism R_GF6PTA equation: [c] : f6p + gln-L --> gam6p + glu-L
name: glutamine-fructose-6-phosphate transaminase
reversible: false
product: 067366
fast: false
reactant: 067341

090840
stoichiometry: 103.0
species: 034412
type: SpeciesReference

044669
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: stearidonyl coenzyme A_C39H58N7O17P3S
type: Species

103982
stoichiometry: 3.0
species: 027181
type: SpeciesReference

029813
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: _4,8 dimethylnonanoyl carnitine_C18H37NO4
type: Species

110221
stoichiometry: 5.0
species: 046235
type: SpeciesReference

142656
stoichiometry: 1.0
species: 034253
type: SpeciesReference

019524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: (R)-Propane-1,2-diol_C3H8O2
type: Species

043897
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Sedoheptulose 7-phosphate_C7H13O10P
type: Species

051204
stoichiometry: 6.0
species: 042331
type: SpeciesReference

098032
stoichiometry: 1.0
species: 034351
type: SpeciesReference

039225
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Melatonin_C13H16N2O2
type: Species

925937
reactant: 069695
product: 069743
is: ENSMMUG00000003325.2
reversible: true
fast: false
product: 069767
reactant: 069719
reactant: 069731
is: http://identifiers.org/ec-code/1.4.3.5
notes: R_PDX5PO subsystem: Vitamin B6 Metabolism R_PDX5PO equation: [c] : o2 + pdx5p <==> h2o2 + pydx5p R_PYAM5POr subsystem: Vitamin B6 Metabolism R_PYAM5POr equation: [c] : h2o + o2 + pyam5p <==> h2o2 + nh4 + pydx5p
reactant: 069707
product: 069755
type: Reaction

070068
stoichiometry: 1.0
species: 020978
type: SpeciesReference

151078
stoichiometry: 1.0
species: 042668
type: SpeciesReference

140713
stoichiometry: 1.0
species: 032657
type: SpeciesReference

095559
stoichiometry: 1.0
species: 026396
type: SpeciesReference

038863
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1665H2740N20O570P20
type: Species

077255
stoichiometry: 1.0
species: 041621
type: SpeciesReference

060349
stoichiometry: 1.0
species: 034363
type: SpeciesReference

093751
stoichiometry: 1.0
species: 043416
type: SpeciesReference

039164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: D-Mannose_C6H12O6
type: Species

071221
stoichiometry: 1.0
species: 031738
type: SpeciesReference

036848
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 17_C157H252N11O127S5X
type: Species

086446
stoichiometry: 3.0
species: 034387
type: SpeciesReference

149737
stoichiometry: 1.0
species: 032826
type: SpeciesReference

071741
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species: 044729
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135855
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species: 038766
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is: http://identifiers.org/ec-code/6.4.1.1
reversible: false
product: 139797
reactant: 139761
is: ENSMMUG00000004533.2
product: 139809
reactant: 139737
name: pyruvate carboxylase
type: Reaction
reactant: 139749
product: 139785
notes: R_PCm subsystem: Pyruvate Metabolism R_PCm equation: [m] : atp + hco3 + pyr --> adp + h + oaa + pi
product: 139773
fast: false

148324
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species: 033628
type: SpeciesReference

080070
stoichiometry: 1.0
species: 023211
type: SpeciesReference

059915
stoichiometry: 1.0
species: 034351
type: SpeciesReference

108618
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species: 019537
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096359
stoichiometry: 1.0
species: 040620
type: SpeciesReference

076893
stoichiometry: 1.0
species: 042211
type: SpeciesReference

117631
stoichiometry: 1.0
species: 033299
type: SpeciesReference

104174
stoichiometry: 2.0
species: 042993
type: SpeciesReference

023502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: N-Acetyl-D-glucosamine_C8H15NO6
type: Species

052170
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species: 027181
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081359
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species: 030795
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

932413
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reactant: 131582
is: ENSMMUG00000012280.2
product: 132004
reactant: 131218
product: 131919
reactant: 131401
product: 131751
reactant: 131303
product: 131847
reactant: 131425
product: 131799
reversible: false
type: Reaction
product: 132028
reactant: 131182
reactant: 131413
product: 131871
reactant: 131606
reactant: 131497
reactant: 131449
is: ENSMMUG00000018173.2
product: 131642
reactant: 131206
reactant: 131437
reactant: 131522
reactant: 131291
product: 131726
reactant: 131594
reactant: 131510
reactant: 131534
product: 131823
reactant: 131339
product: 131775
product: 131690
reactant: 131194
reactant: 131327
reactant: 131546
product: 131835
product: 131980
product: 131943
product: 131895
is: http://identifiers.org/ec-code/2.4.1.149
product: 131630
reactant: 131243
product: 131992
product: 131883
product: 131702
reactant: 131230
product: 131678
product: 131654
reactant: 131267
reactant: 131352
product: 131907
reactant: 131255
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reactant: 131558
reactant: 131461
product: 131787
reactant: 131364
fast: false
product: 132016
product: 131931
reactant: 131485
product: 131859
product: 131618
reactant: 131388
reactant: 131473
product: 132040
product: 131955
product: 131714
product: 131666
product: 131967
reactant: 131570
product: 131811
reactant: 131376
product: 131738
reactant: 131279
product: 131763

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species: 028303
type: SpeciesReference

140823
stoichiometry: 2.0
species: 043452
type: SpeciesReference

074987
stoichiometry: 1.0
species: 026359
type: SpeciesReference

144498
stoichiometry: 1.0
species: 045080
type: SpeciesReference

119402
stoichiometry: 1.0
species: 035544
type: SpeciesReference

086859
stoichiometry: 1.0
species: 033263
type: SpeciesReference

121102
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species: 024010
type: SpeciesReference

148999
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species: 032947
type: SpeciesReference

110873
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species: 024889
type: SpeciesReference

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species: 039008
type: SpeciesReference

100262
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species: 024010
type: SpeciesReference

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species: 032789
type: SpeciesReference

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initial amount: NaN
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species: 037886
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
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stoichiometry: 1.0
species: 045875
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118474
stoichiometry: 3.0
species: 028571
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
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initial amount: NaN
in compartment: 019205
type: Species

102145
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species: 023271
type: SpeciesReference

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species: 034363
type: SpeciesReference

121704
stoichiometry: 1.0
species: 034387
type: SpeciesReference

077013
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species: 046283
type: SpeciesReference

039426
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
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type: Species

043488
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Pyruvate_C3H3O3
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
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type: Species

059605
stoichiometry: 1.0
species: 045741
type: SpeciesReference

137797
stoichiometry: 2.0
species: 040198
type: SpeciesReference

072211
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species: 034327
type: SpeciesReference

043753
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Riboflavin_C17H20N4O6
type: Species

019925
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: cis-2-Hydroxy cinnamate_C9H7O3
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929299
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reactant: 100890
product: 100914
fast: false
is: ENSMMUG00000000584.2
reactant: 100878
is: ENSMMUG00000003897.2
type: Reaction
product: 100938
reactant: 100902
reversible: true
product: 100926

058301
stoichiometry: 1.0
species: 037996
type: SpeciesReference

099995
stoichiometry: 2.0
species: 039849
type: SpeciesReference

078959
stoichiometry: 2.0
species: 034253
type: SpeciesReference

046295
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
type: Species

150909
stoichiometry: 3.0
species: 044174
type: SpeciesReference

079286
stoichiometry: 1.0
species: 034363
type: SpeciesReference

048019
stoichiometry: 1.0
species: 021050
type: SpeciesReference

143933
stoichiometry: 1.0
species: 026856
type: SpeciesReference

053615
stoichiometry: 1.0
species: 039390
type: SpeciesReference

065705
stoichiometry: 1.0
species: 036836
type: SpeciesReference

141065
stoichiometry: 1.0
species: 034448
type: SpeciesReference

074567
stoichiometry: 1.0
species: 025541
type: SpeciesReference

088040
stoichiometry: 1.0
species: 033505
type: SpeciesReference

931357
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fast: false
reversible: false
reactant: 121728
reactant: 121752
type: Reaction
is: http://identifiers.org/ec-code/3.2.1.49
is: ENSMMUG00000001267.2
product: 121800
product: 121776
product: 121788
reactant: 121740
notes: R_NAGAly subsystem: Sphingolipid Metabolism R_NAGAly equation: [l] : acgagbside_hs + h + udp --> gbside_hs + udpacgal R_NAGA2ly subsystem: Keratan sulfate degradation R_NAGA2ly equation: [l] : Tn_antigen + h + udp --> Ser/Thr + udpacgal

121428
stoichiometry: 1.0
species: 022111
type: SpeciesReference

124302
stoichiometry: 1.0
species: 032560
type: SpeciesReference

083194
stoichiometry: 1.0
species: 041501
type: SpeciesReference

101083
stoichiometry: 1.0
species: 032584
type: SpeciesReference

023889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Adenine_C5H5N5
type: Species

067523
stoichiometry: 1.0
species: 040306
type: SpeciesReference

073190
stoichiometry: 1.0
species: 025939
type: SpeciesReference

064898
stoichiometry: 2.0
species: 034253
type: SpeciesReference

072295
stoichiometry: 1.0
species: 042355
type: SpeciesReference

070927
stoichiometry: 1.0
species: 029030
type: SpeciesReference

031883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Type IH glycolipid_C50H89N2O26FULLRCO
type: Species

144534
stoichiometry: 1.0
species: 038381
type: SpeciesReference

054833
stoichiometry: 1.0
species: 038610
type: SpeciesReference

107678
stoichiometry: 1.0
species: 023454
type: SpeciesReference

132642
stoichiometry: 2.0
species: 040029
type: SpeciesReference

124748
stoichiometry: 3.0
species: 042283
type: SpeciesReference

934060
product: 148275
product: 148251
reversible: false
notes: R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PSP_L subsystem: Glycine, Serine, and Threonine Metabolism R_PSP_L equation: [c] : h2o + pser-L --> pi + ser-L
product: 148239
product: 148263
is: http://identifiers.org/ec-code/3.1.3.3
reactant: 148215
type: Reaction
fast: false
reactant: 148202
is: ENSMMUG00000007490.2
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 148227

085529
stoichiometry: 1.0
species: 041838
type: SpeciesReference

116122
stoichiometry: 1.0
species: 040620
type: SpeciesReference

053760
stoichiometry: 2.0
species: 041742
type: SpeciesReference

106173
stoichiometry: 1.0
species: 034363
type: SpeciesReference

065957
stoichiometry: 1.0
species: 039849
type: SpeciesReference

095235
stoichiometry: 1.0
species: 027181
type: SpeciesReference

108486
stoichiometry: 1.0
species: 021606
type: SpeciesReference

047971
stoichiometry: 1.0
species: 024561
type: SpeciesReference

043608
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: cis-11-retinal_C20H28O
type: Species

082238
stoichiometry: 2.0
species: 027097
type: SpeciesReference

084132
stoichiometry: 1.0
species: 036125
type: SpeciesReference

081899
stoichiometry: 1.0
species: 030090
type: SpeciesReference

076303
stoichiometry: 1.0
species: 033457
type: SpeciesReference

097287
stoichiometry: 1.0
species: 031375
type: SpeciesReference

051746
stoichiometry: 3.0
species: 034363
type: SpeciesReference

060553
stoichiometry: 1.0
species: 040306
type: SpeciesReference

041549
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2
type: Species

125145
stoichiometry: 1.0
species: 034436
type: SpeciesReference

112526
stoichiometry: 12.0
species: 034253
type: SpeciesReference

042932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: D-Proline_C5H9NO2
type: Species

057491
stoichiometry: 1.0
species: 019385
type: SpeciesReference

047429
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Zymostenol_C27H46O
type: Species

026904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: clupanodonyl CoA_C43H64N7O17P3S
type: Species

062825
stoichiometry: 1.0
species: 027181
type: SpeciesReference

044995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: taurochenodeoxycholate_C26H45NO6S
type: Species

925360
fast: false
type: Reaction
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product: 064332
reactant: 064272
product: 064320
product: 064308
reactant: 064284
reactant: 064260
is: http://identifiers.org/ec-code/2.4.99.8
reversible: false
is: ENSMMUG00000003685.2
notes: R_ST8SIA12 subsystem: Sphingolipid Metabolism R_ST8SIA12 equation: [g] : cmpacna + gm3_hs --> cmp + gd3_hs + h R_ST8SIA11 subsystem: Sphingolipid Metabolism R_ST8SIA11 equation: [g] : acngalgbside_hs + cmpacna --> acnacngalgbside_hs + cmp + h

931717
notes: R_MI4PP subsystem: Inositol Phosphate Metabolism R_MI4PP equation: [c] : h2o + mi4p-D --> inost + pi R_MI3PP subsystem: Inositol Phosphate Metabolism R_MI3PP equation: [c] : h2o + mi3p-D --> inost + pi R_MI1PP subsystem: Inositol Phosphate Metabolism R_MI1PP equation: [c] : h2o + mi1p-D --> inost + pi
reactant: 124724
product: 124760
product: 124748
is: ENSMMUG00000010471.2
reversible: false
reactant: 124712
fast: false
is: http://identifiers.org/ec-code/3.1.3.25
reactant: 124736
type: Reaction
reactant: 124700

064103
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species: 033275
type: SpeciesReference

105211
stoichiometry: 3.0
species: 034412
type: SpeciesReference

028291
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Hydrogen cyanide_CHN
type: Species

093679
stoichiometry: 1.0
species: 041597
type: SpeciesReference

137580
stoichiometry: 1.0
species: 026698
type: SpeciesReference

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species: 022692
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species: 039390
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
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type: Species

102470
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species: 032911
type: SpeciesReference

061010
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species: 040162
type: SpeciesReference

126508
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species: 028352
type: SpeciesReference

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species: 034363
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species: 040282
type: SpeciesReference

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species: 043440
type: SpeciesReference

120789
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species: 040138
type: SpeciesReference

052024
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species: 045887
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _2-Hydroxybutyrate_C4H7O3
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023199
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
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type: Species

126640
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species: 033616
type: SpeciesReference

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species: 034833
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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052882
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species: 041669
type: SpeciesReference

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species: 025541
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
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type: Species

022003
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

093967
stoichiometry: 1.0
species: 034253
type: SpeciesReference

131255
stoichiometry: 1.0
species: 032464
type: SpeciesReference

033227
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Glyoxylate_C2H1O3
type: Species

039812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human liver homolog_C1300H2128N20O220P20
type: Species

089561
stoichiometry: 1.0
species: 037560
type: SpeciesReference

071957
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species: 025045
type: SpeciesReference

923632
reactant: 048368
reactant: 048380
reactant: 048392
product: 048416
is: http://identifiers.org/ec-code/1.8.1.9
notes: R_TRDRm subsystem: Nucleotides R_TRDRm equation: [m] : h + nadph + trdox --> nadp + trdrd
reversible: false
is: ENSMMUG00000001714.2
name: thioredoxin reductase (NADPH)
type: Reaction
is: ENSMMUG00000017147.2
product: 048404
fast: false

927017
product: 078258
product: 078233
product: 078209
product: 078184
product: 078246
reactant: 078088
product: 078221
reactant: 078148
product: 078172
is: http://identifiers.org/ec-code/3.1.2.14
reactant: 078076
reactant: 078124
is: ENSMMUG00000010590.2
is: ENSMMUG00000016267.2
product: 078283
reactant: 078136
type: Reaction
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reversible: true
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product: 078197
reactant: 078064
reactant: 078160
reactant: 078112
reactant: 078100
fast: false

139073
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species: 028497
type: SpeciesReference

132485
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species: 046476
type: SpeciesReference

152004
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species: 040789
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075508
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149957
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069659
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species: 027626
type: SpeciesReference

057975
stoichiometry: 1.0
species: 021763
type: SpeciesReference

127305
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species: 043596
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127062
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species: 025782
type: SpeciesReference

043187
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Propenoyl-CoA_C24H34N7O17P3S
type: Species

130176
stoichiometry: 1.0
species: 039981
type: SpeciesReference

040885
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Superoxide anion_O2
type: Species

020447
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
type: Species

087523
stoichiometry: 1.0
species: 027966
type: SpeciesReference

924424
reactant: 054942
reactant: 054954
product: 055075
reactant: 055015
reversible: false
product: 055087
is: http://identifiers.org/ec-code/2.3.1.86
type: Reaction
reactant: 055002
product: 055051
product: 055125
product: 055111
notes: R_FAEL184 subsystem: Fatty acid elongation R_FAEL184 equation: [c] : (5) h + malcoa + (4) nadph + o2 + strdnccoa --> co2 + coa + eicostetcoa + (3) h2o + (4) nadp R_FAEL183 subsystem: Fatty acid elongation R_FAEL183 equation: [c] : (5) h + lnlncgcoa + malcoa + (4) nadph + o2 --> co2 + coa + dlnlcgcoa + (3) h2o + (4) nadp R_FAEL205 subsystem: Fatty acid elongation R_FAEL205 equation: [c] : (5) h + malcoa + (4) nadph + o2 + tmndnccoa --> clpndcoa + co2 + coa + (3) h2o + (4) nadp R_FAEL204 subsystem: Fatty acid elongation R_FAEL204 equation: [c] : arachdcoa + (5) h + malcoa + (4) nadph + o2 --> adrncoa + co2 + coa + (3) h2o + (4) nadp
is: ENSMMUG00000020208.2
product: 055039
product: 055063
product: 055099
reactant: 054978
reactant: 054966
reactant: 055027
fast: false
reactant: 054990

105079
stoichiometry: 1.0
species: 024034
type: SpeciesReference

140508
stoichiometry: 1.0
species: 023162
type: SpeciesReference

105680
stoichiometry: 5.0
species: 024646
type: SpeciesReference

933640
reactant: 142524
product: 142596
reversible: false
is: ENSMMUG00000016857.1
reactant: 142536
notes: R_PGS subsystem: Eicosanoid Metabolism R_PGS equation: [c] : arachd + h + nadph + (2) o2 --> h2o + nadp + prostgh2 R_PGSr subsystem: Eicosanoid Metabolism R_PGSr equation: [r] : arachd + h + nadph + (2) o2 --> h2o + nadp + prostgh2
reactant: 142572
reactant: 142499
type: Reaction
product: 142656
reactant: 142584
is: http://identifiers.org/ec-code/1.14.99.1
product: 142632
product: 142644
is: ENSMMUG00000012886.2
product: 142620
product: 142608
reactant: 142511
reactant: 142560
reactant: 142548
fast: false

025529
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Aspartate_C4H6NO4
type: Species

931945
product: 126496
name: urocanase
notes: R_URCN subsystem: Histidine Metabolism R_URCN equation: [c] : h2o + urcan --> 4izp
fast: false
type: Reaction
is: ENSMMUG00000004197.2
reactant: 126484
reactant: 126472
reversible: false
is: http://identifiers.org/ec-code/4.2.1.49

058758
stoichiometry: 1.0
species: 039655
type: SpeciesReference

068174
stoichiometry: 1.0
species: 044742
type: SpeciesReference

035037
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: heptadecanoyl coa_C38H64N7O17P3S
type: Species

066125
stoichiometry: 1.0
species: 023466
type: SpeciesReference

071330
stoichiometry: 1.0
species: 040270
type: SpeciesReference

129272
stoichiometry: 2.0
species: 039716
type: SpeciesReference

142427
stoichiometry: 1.0
species: 022208
type: SpeciesReference

120032
stoichiometry: 1.0
species: 034725
type: SpeciesReference

026820
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Citrulline_C6H13N3O3
type: Species

070598
stoichiometry: 1.0
species: 037742
type: SpeciesReference

033749
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: glycophosphatidylinositol (GPI) anchor precursor (3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol) (H8)_C55H106N4O38P4FULLRCO2FULLR2CO2
type: Species

025106
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: (+)-alpha-Pinene_C10H16
type: Species

068029
stoichiometry: 1.0
species: 033517
type: SpeciesReference

078729
stoichiometry: 1.0
species: 040813
type: SpeciesReference

103777
stoichiometry: 4.0
species: 034253
type: SpeciesReference

070370
stoichiometry: 1.0
species: 022135
type: SpeciesReference

113924
stoichiometry: 1.0
species: 037172
type: SpeciesReference

110668
stoichiometry: 1.0
species: 037874
type: SpeciesReference

099102
stoichiometry: 1.0
species: 020593
type: SpeciesReference

933928
product: 147155
product: 147167
reactant: 147143
reversible: true
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c]
is: ENSMMUG00000001740.2
reactant: 147131
type: Reaction
product: 147179
reactant: 147119
fast: false

125495
stoichiometry: 1.0
species: 039849
type: SpeciesReference

141270
stoichiometry: 1.0
species: 020738
type: SpeciesReference

135649
stoichiometry: 1.0
species: 044283
type: SpeciesReference

074279
stoichiometry: 2.0
species: 024010
type: SpeciesReference

064465
stoichiometry: 2.0
species: 034179
type: SpeciesReference

030795
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: estradiol glucuronide_C24H32O8
type: Species

097803
stoichiometry: 1.0
species: 042752
type: SpeciesReference

141125
stoichiometry: 1.0
species: 037754
type: SpeciesReference

114623
stoichiometry: 1.0
species: 036631
type: SpeciesReference

049695
stoichiometry: 2.0
species: 034327
type: SpeciesReference

149083
stoichiometry: 5.0
species: 025577
type: SpeciesReference

053844
stoichiometry: 1.0
species: 036740
type: SpeciesReference

079081
stoichiometry: 1.0
species: 025433
type: SpeciesReference

048163
stoichiometry: 1.0
species: 035157
type: SpeciesReference

130467
stoichiometry: 11.0
species: 040150
type: SpeciesReference

031725
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Ley glycolipid_C56H99N2O30FULLRCO
type: Species

048428
stoichiometry: 1.0
species: 034253
type: SpeciesReference

134122
stoichiometry: 2.0
species: 032221
type: SpeciesReference

108923
stoichiometry: 1.0
species: 035774
type: SpeciesReference

137568
stoichiometry: 1.0
species: 024780
type: SpeciesReference

128522
stoichiometry: 1.0
species: 032076
type: SpeciesReference

072803
stoichiometry: 1.0
species: 034140
type: SpeciesReference

062282
stoichiometry: 1.0
species: 032536
type: SpeciesReference

106884
stoichiometry: 1.0
species: 044533
type: SpeciesReference

117728
stoichiometry: 2.0
species: 034253
type: SpeciesReference

025867
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Biocytin_C16H28N4O4S
type: Species

054110
stoichiometry: 3.0
species: 028534
type: SpeciesReference

062403
stoichiometry: 1.0
species: 043536
type: SpeciesReference

041886
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Phosphocreatine_C4H9N3O5P
type: Species

092703
stoichiometry: 8.0
species: 030212
type: SpeciesReference

092149
stoichiometry: 1.0
species: 043283
type: SpeciesReference

020605
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3
type: Species

113019
stoichiometry: 1.0
species: 022969
type: SpeciesReference

025300
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: C20:4-CoA_C41H62N7O17P3S
type: Species

048572
stoichiometry: 2.0
species: 044911
type: SpeciesReference

928999
reactant: 097347
product: 097419
reactant: 097311
fast: false
notes: R_DESAT24_1 subsystem: Fatty acid elongation R_DESAT24_1 equation: [c] : h + nadh + o2 + tetpent3coa --> (2) h2o + nad + tethex3coa R_DESAT18_8 subsystem: Fatty acid elongation R_DESAT18_8 equation: [c] : h + nadh + o2 + od2coa --> (2) h2o + lneldccoa + nad R_DESAT18_9 subsystem: Fatty acid elongation R_DESAT18_9 equation: [c] : h + lnlccoa + nadh + o2 --> (2) h2o + lnlncgcoa + nad R_DESAT18_6 subsystem: Fatty acid elongation R_DESAT18_6 equation: [c] : h + nadh + o2 + odecoa --> (2) h2o + lneldccoa + nad R_DESAT18_10 subsystem: Fatty acid elongation R_DESAT18_10 equation: [c] : h + lnlncacoa + nadh + o2 --> (2) h2o + nad + strdnccoa R_DESAT18_7 subsystem: Fatty acid elongation R_DESAT18_7 equation: [c] : h + nadh + o2 + vacccoa --> (2) h2o + lneldccoa + nad
is: ENSMMUG00000000327.2
product: 097467
is: ENSMMUG00000005151.2
is: http://identifiers.org/ec-code/1.14.19.1
product: 097407
reactant: 097323
reactant: 097383
reactant: 097395
is: ENSMMUG00000000328.2
reactant: 097359
product: 097455
reactant: 097371
reactant: 097299
product: 097443
type: Reaction
reactant: 097335
product: 097431
reversible: false

035314
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 3_C81H117N5O97S10
type: Species

077461
stoichiometry: 1.0
species: 023066
type: SpeciesReference

151343
stoichiometry: 1.0
species: 031919
type: SpeciesReference

117402
stoichiometry: 2.0
species: 026977
type: SpeciesReference

061730
stoichiometry: 1.0
species: 033119
type: SpeciesReference

024489
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: _1-alkyldihydroxyacetone phosphate_C3H4O6PFULLRC2H4
type: Species

078513
stoichiometry: 1.0
species: 019973
type: SpeciesReference

084699
stoichiometry: 1.0
species: 045754
type: SpeciesReference

066233
stoichiometry: 1.0
species: 028243
type: SpeciesReference

123457
stoichiometry: 4.0
species: 040849
type: SpeciesReference

036413
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 24_C118H191N8O101S5
type: Species

924136
is: http://identifiers.org/ec-code/2.6.1.1
is: http://identifiers.org/ec-code/2.6.1.3
modifier: 052785
modifier: 052773
modifier: 052688
is: http://identifiers.org/ec-code/2.6.1.58
reactant: 052616
modifier: 052761
product: 052676
is: http://identifiers.org/ec-code/2.6.1.5
fast: false
modifier: 052749
is: ENSMMUG00000010356.2
modifier: 052737
product: 052664
type: Reaction
reactant: 052628
notes: R_EHGLAT subsystem: Arginine and Proline Metabolism R_EHGLAT equation: [c] : akg + e4hglu --> 4h2oglt + glu-L R_LCYSTAT subsystem: Cysteine Metabolism R_LCYSTAT equation: [c] : Lcyst + akg <==> 3spyr + glu-L R_CYSTA subsystem: Cysteine Metabolism R_CYSTA equation: [c] : akg + cys-L <==> glu-L + mercppyr R_ASPTA subsystem: Alanine and Aspartate Metabolism R_ASPTA equation: [c] : akg + asp-L <==> glu-L + oaa R_3SALATAi subsystem: Cysteine Metabolism R_3SALATAi equation: [c] : 3sala + akg + h --> 3snpyr + glu-L R_TYRTA subsystem: Tyrosine metabolism R_TYRTA equation: [c] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1 subsystem: Phenylalanine metabolism R_PHETA1 equation: [c] : akg + phe-L <==> glu-L + phpyr
modifier: 052821
reversible: false
modifier: 052725
modifier: 052809
reactant: 052640
product: 052652
modifier: 052712
reactant: 052604
modifier: 052797
modifier: 052700

070273
stoichiometry: 1.0
species: 019485
type: SpeciesReference

112382
stoichiometry: 2.0
species: 024010
type: SpeciesReference

049671
stoichiometry: 2.0
species: 040246
type: SpeciesReference

040186
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2
type: Species

148553
stoichiometry: 1.0
species: 027530
type: SpeciesReference

031423
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Formate_CH1O2
type: Species

024154
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: adrenic acid_C22H35O2
type: Species

112971
stoichiometry: 1.0
species: 046307
type: SpeciesReference

044017
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Se-Adenosylselenomethionine_C15H23N6O5Se
type: Species

060878
stoichiometry: 2.0
species: 024010
type: SpeciesReference

022232
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heptaglutamyl folate (DHF)_C49H55N13O24
type: Species

056853
stoichiometry: 1.0
species: 044633
type: SpeciesReference

138953
stoichiometry: 1.0
species: 041681
type: SpeciesReference

075096
stoichiometry: 1.0
species: 042548
type: SpeciesReference

106416
stoichiometry: 1.0
species: 019537
type: SpeciesReference

085204
stoichiometry: 1.0
species: 027145
type: SpeciesReference

140195
stoichiometry: 1.0
species: 036944
type: SpeciesReference

050372
stoichiometry: 1.0
species: 034809
type: SpeciesReference

126267
stoichiometry: 1.0
species: 026650
type: SpeciesReference

032379
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)6 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C96H165N4O60FULLRCO
type: Species

028534
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2
type: Species

113392
stoichiometry: 1.0
species: 032850
type: SpeciesReference

069429
stoichiometry: 1.0
species: 027434
type: SpeciesReference

147179
stoichiometry: 2.0
species: 034532
type: SpeciesReference

102241
stoichiometry: 1.0
species: 036089
type: SpeciesReference

102675
stoichiometry: 1.0
species: 024034
type: SpeciesReference

113657
stoichiometry: 1.0
species: 040946
type: SpeciesReference

057155
stoichiometry: 1.0
species: 043873
type: SpeciesReference

117848
stoichiometry: 2.0
species: 038923
type: SpeciesReference

927185
reversible: true
is: ENSMMUG00000017409.2
is: http://identifiers.org/ec-code/1.1.1.49
product: 079310
name: glucose 6-phosphate dehydrogenase
reactant: 079274
product: 079298
fast: false
type: Reaction
reactant: 079262
product: 079286
notes: R_G6PDH2r subsystem: Pentose Phosphate Pathway R_G6PDH2r equation: [c] : g6p + nadp <==> 6pgl + h + nadph

037244
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate II (core 2-linked), degradation product 5_C50H82N4O38SX
type: Species

064332
stoichiometry: 1.0
species: 032729
type: SpeciesReference

098308
stoichiometry: 1.0
species: 041211
type: SpeciesReference

055211
stoichiometry: 1.0
species: 043452
type: SpeciesReference

042235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: phytanic acid_C20H39O2
type: Species

930842
product: 116098
product: 116086
reactant: 115844
product: 115978
product: 116014
product: 116002
fast: false
notes: R_NDPK9 subsystem: Nucleotides R_NDPK9 equation: [c] : atp + idp <==> adp + itp R_NDPK8 subsystem: Nucleotides R_NDPK8 equation: [c] : atp + dadp <==> adp + datp R_NDPK2 subsystem: Nucleotides R_NDPK2 equation: [c] : atp + udp <==> adp + utp R_NDPK6 subsystem: Nucleotides R_NDPK6 equation: [c] : atp + dudp <==> adp + dutp R_NDPK5 subsystem: Nucleotides R_NDPK5 equation: [c] : atp + dgdp <==> adp + dgtp R_NDPK3 subsystem: Nucleotides R_NDPK3 equation: [c] : atp + cdp <==> adp + ctp R_NDPK4 subsystem: Nucleotides R_NDPK4 equation: [c] : atp + dtdp <==> adp + dttp R_NDPK1 subsystem: Nucleotides R_NDPK1 equation: [c] : atp + gdp <==> adp + gtp R_NDPK7 subsystem: Nucleotides R_NDPK7 equation: [c] : atp + dcdp <==> adp + dctp R_NDPK10 subsystem: Nucleotides R_NDPK10 equation: [c] : atp + didp <==> adp + ditp
is: ENSMMUG00000021079.2
reactant: 115868
reactant: 115954
reactant: 115941
product: 116038
reversible: true
product: 116026
is: ENSMMUG00000004867.2
reactant: 115917
product: 115990
reactant: 115856
product: 116050
is: http://identifiers.org/ec-code/2.7.4.6
reactant: 115893
is: ENSMMUG00000023712.2
type: Reaction
reactant: 115880
product: 116074
is: ENSMMUG00000003078.2
reactant: 115966
is: ENSMMUG00000030981.1
product: 116062
reactant: 115929
reactant: 115905

098994
stoichiometry: 1.0
species: 029716
type: SpeciesReference

090116
stoichiometry: 1.0
species: 031217
type: SpeciesReference

145879
stoichiometry: 2.0
species: 036558
type: SpeciesReference

098464
stoichiometry: 1.0
species: 022656
type: SpeciesReference

047657
stoichiometry: 3.0
species: 034399
type: SpeciesReference

029788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

019683
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _1-alpha,25-Dihydroxyvitamin D2_C28H44O3
type: Species

134676
stoichiometry: 1.0
species: 024694
type: SpeciesReference

091414
stoichiometry: 15.0
species: 041754
type: SpeciesReference

147287
stoichiometry: 1.0
species: 033749
type: SpeciesReference

150922
stoichiometry: 1.0
species: 044441
type: SpeciesReference

027302
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Cortisone_C21H28O5
type: Species

019265
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19
type: Species

119148
stoichiometry: 1.0
species: 042283
type: SpeciesReference

041283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: D-Ornithine_C5H13N2O2
type: Species

055620
stoichiometry: 4.0
species: 044331
type: SpeciesReference

073603
stoichiometry: 1.0
species: 042403
type: SpeciesReference

061454
stoichiometry: 1.0
species: 036161
type: SpeciesReference

085758
stoichiometry: 1.0
species: 045959
type: SpeciesReference

066450
stoichiometry: 1.0
species: 034363
type: SpeciesReference

118318
stoichiometry: 1.0
species: 038996
type: SpeciesReference

075786
stoichiometry: 1.0
species: 033082
type: SpeciesReference

129597
stoichiometry: 1.0
species: 026323
type: SpeciesReference

096782
stoichiometry: 1.0
species: 025505
type: SpeciesReference

030929
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: estrone glucuronide_C24H30O8
type: Species

090575
stoichiometry: 1.0
species: 038248
type: SpeciesReference

082468
stoichiometry: 1.0
species: 034088
type: SpeciesReference

020894
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3-Sulfino-L-alanine_C3H5NO4S
type: Species

036137
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: ITP_C10H11N4O14P3
type: Species

109441
stoichiometry: 1.0
species: 045393
type: SpeciesReference

051902
stoichiometry: 1.0
species: 034363
type: SpeciesReference

145467
stoichiometry: 1.0
species: 037268
type: SpeciesReference

033457
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Glycolate_C2H3O3
type: Species

046067
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: tetradecanoate (n-C14:0)_C14H27O2
type: Species

049521
stoichiometry: 1.0
species: 042283
type: SpeciesReference

925516
reactant: 065801
is: http://identifiers.org/ec-code/2.6.1.52
type: Reaction
reactant: 065813
reversible: false
product: 065825
is: ENSMMUG00000018263.2
name: phosphoserine transaminase
is: ENSMMUG00000019516.1
fast: false
notes: R_PSERT subsystem: Glycine, Serine, and Threonine Metabolism R_PSERT equation: [c] : 3php + glu-L --> akg + pser-L
is: ENSMMUG00000011868.2
product: 065837

926753
reactant: 076036
type: Reaction
is: ENSMMUG00000023556.2
product: 076060
product: 076084
notes: R_SBPP1er subsystem: Sphingolipid Metabolism R_SBPP1er equation: [r] : h2o + sph1p --> pi + sphgn R_SBPP3er subsystem: Sphingolipid Metabolism R_SBPP3er equation: [r] : h2o + sphs1p --> pi + sphings
reactant: 076024
reversible: false
reactant: 076048
fast: false
product: 076072

073046
stoichiometry: 1.0
species: 026771
type: SpeciesReference

053990
stoichiometry: 1.0
species: 030892
type: SpeciesReference

065151
stoichiometry: 1.0
species: 042115
type: SpeciesReference

099404
stoichiometry: 1.0
species: 032584
type: SpeciesReference

060986
stoichiometry: 1.0
species: 040102
type: SpeciesReference

093739
stoichiometry: 1.0
species: 034166
type: SpeciesReference

108065
stoichiometry: 1.0
species: 040885
type: SpeciesReference

040498
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Nicotinate D-ribonucleotide_C11H12NO9P
type: Species

037946
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Leukotriene B4_C20H31O4
type: Species

038489
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Lysine_C6H15N2O2
type: Species

116219
stoichiometry: 1.0
species: 020617
type: SpeciesReference

029211
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Dihydroxyacetone phosphate_C3H5O6P
type: Species

139773
stoichiometry: 1.0
species: 040933
type: SpeciesReference

038164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: linoelaidic acid (all trans C18:2)_C18H31O2
type: Species

928770
reactant: 095848
product: 095872
reactant: 095836
reactant: 095824
is: http://identifiers.org/ec-code/4.2.1.17
reversible: true
reactant: 095812
type: Reaction
product: 095860
fast: false
product: 095884
is: ENSMMUG00000014927.2
notes: R_ECOAH1x subsystem: Tryptophan metabolism R_ECOAH1x equation: [x] : 3hbcoa <==> b2coa + h2o R_C2M26DCOAHLx subsystem: Limonene and pinene degradation R_C2M26DCOAHLx equation: [x] : c2m26dcoa + h2o <==> 3h26dm5coa R_T2M26DCOAHLx subsystem: Limonene and pinene degradation R_T2M26DCOAHLx equation: [x] : h2o + t2m26dcoa <==> 3h26dm5coa

088919
stoichiometry: 1.0
species: 040102
type: SpeciesReference

036558
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 35_C68H113N4O54S1
type: Species

094161
stoichiometry: 1.0
species: 039752
type: SpeciesReference

059266
stoichiometry: 1.0
species: 028788
type: SpeciesReference

039390
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Methionine_C5H11NO2S
type: Species

133754
stoichiometry: 3.0
species: 031181
type: SpeciesReference

063766
stoichiometry: 1.0
species: 040282
type: SpeciesReference

036293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 16_C160H258N11O137S7
type: Species

064705
stoichiometry: 1.0
species: 027013
type: SpeciesReference

146841
stoichiometry: 1.0
species: 028692
type: SpeciesReference

050637
stoichiometry: 1.0
species: 031968
type: SpeciesReference

047766
stoichiometry: 1.0
species: 037790
type: SpeciesReference

106017
stoichiometry: 1.0
species: 044778
type: SpeciesReference

124977
stoichiometry: 1.0
species: 034253
type: SpeciesReference

061430
stoichiometry: 6.0
species: 040102
type: SpeciesReference

046139
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Tyramine O-sulfate_C8H11NO4S
type: Species

030649
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Eicosatetranoyl carnitine_C27H45NO4
type: Species

929711
reactant: 103969
reactant: 103957
reactant: 103945
product: 104018
notes: R_SUCOAS1m subsystem: Citric Acid Cycle R_SUCOAS1m equation: [m] : coa + gtp + succ <==> gdp + pi + succoa R_MECOAS1m subsystem: C5-Branched dibasic acid metabolism R_MECOAS1m equation: [m] : coa + gtp + mescon <==> gdp + mescoa + pi R_ITCOAL1m subsystem: C5-Branched dibasic acid metabolism R_ITCOAL1m equation: [m] : coa + gtp + itacon <==> gdp + itaccoa + pi
is: http://identifiers.org/ec-code/6.2.1.4
type: Reaction
is: ENSMMUG00000009693.2
is: ENSMMUG00000005640.2
product: 104054
reversible: true
product: 104006
reactant: 103994
product: 104030
reactant: 103982
fast: false
product: 104042

148650
stoichiometry: 1.0
species: 022570
type: SpeciesReference

041126
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: octanoate (n-C8:0)_C8H15O2
type: Species

147395
stoichiometry: 2.0
species: 039716
type: SpeciesReference

150812
stoichiometry: 3.0
species: 044162
type: SpeciesReference

045609
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Thymine_C5H6N2O2
type: Species

123349
stoichiometry: 1.0
species: 046488
type: SpeciesReference

026614
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Choline phosphate_C5H13NO4P
type: Species

083615
stoichiometry: 1.0
species: 029522
type: SpeciesReference

068597
stoichiometry: 1.0
species: 019253
type: SpeciesReference

102398
stoichiometry: 1.0
species: 024646
type: SpeciesReference

114117
stoichiometry: 1.0
species: 037064
type: SpeciesReference

145903
stoichiometry: 1.0
species: 027650
type: SpeciesReference

047321
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Xylulose 1-phosphate_C5H9O8P
type: Species

026494
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Choline_C5H14NO
type: Species

139665
stoichiometry: 2.0
species: 035689
type: SpeciesReference

028122
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5a_C45H64N2O51S5X
type: Species

050263
stoichiometry: 1.0
species: 045080
type: SpeciesReference

031532
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Farnesyl diphosphate_C15H25O7P2
type: Species

106307
stoichiometry: 1.0
species: 027121
type: SpeciesReference

057263
stoichiometry: 1.0
species: 033918
type: SpeciesReference

066666
stoichiometry: 1.0
species: 037886
type: SpeciesReference

930998
modifier: 117668
fast: false
notes: R_GHMT2rm subsystem: Glycine, Serine, and Threonine Metabolism R_GHMT2rm equation: [m] : ser-L + thf <==> gly + h2o + mlthf R_GHMT3m subsystem: Lysine Metabolism R_GHMT3m equation: [m] : 3htmelys + h --> 4tmeabut + gly
product: 117631
modifier: 117692
product: 117619
reversible: false
modifier: 117643
is: http://identifiers.org/ec-code/2.1.2.1
type: Reaction
reactant: 117595
is: ENSMMUG00000021785.2
modifier: 117680
modifier: 117656
reactant: 117607

043066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Prostaglandin E1_C20H33O5
type: Species

039861
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Myristoyl-ACP (n-C14:0ACP)_C25H47N2O8PRS
type: Species

117956
stoichiometry: 1.0
species: 033371
type: SpeciesReference

110439
stoichiometry: 1.0
species: 043247
type: SpeciesReference

924844
product: 058614
is: ENSMMUG00000032610.1
is: ENSMMUG00000023378.2
notes: R_CAATPS subsystem: Transport, Extracellular R_CAATPS equation: atp[c] + (2) ca2[c] + h2o[c] --> adp[c] + (2) ca2[e] + h[e] + pi[c]
is: http://identifiers.org/ec-code/3.6.3.6
reactant: 058578
product: 058626
is: ENSMMUG00000011478.2
name: Ca ATPase
reactant: 058590
product: 058650
type: Reaction
is: ENSMMUG00000019938.2
fast: false
is: ENSMMUG00000031394.1
product: 058638
reversible: false
reactant: 058602

022123
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _6-Pyruvoyl-5,6,7,8-tetrahydropterin_C9H11N5O3
type: Species

103535
stoichiometry: 1.0
species: 025288
type: SpeciesReference

091523
stoichiometry: 1.0
species: 035714
type: SpeciesReference

145042
stoichiometry: 1.0
species: 027930
type: SpeciesReference

120489
stoichiometry: 3.0
species: 034363
type: SpeciesReference

082685
stoichiometry: 1.0
species: 031109
type: SpeciesReference

032923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: D-Glucose_C6H12O6
type: Species

033347
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Glycine betaine_C5H11NO2
type: Species

146287
stoichiometry: 1.0
species: 020642
type: SpeciesReference

109333
stoichiometry: 1.0
species: 026614
type: SpeciesReference

048802
stoichiometry: 2.0
species: 031520
type: SpeciesReference

098885
stoichiometry: 1.0
species: 038092
type: SpeciesReference

045959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Testosterone_C19H28O2
type: Species

028424
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Deoxyadenosine_C10H13N5O3
type: Species

102458
stoichiometry: 1.0
species: 032524
type: SpeciesReference

933231
product: 138422
reactant: 138410
notes: R_COAtm subsystem: Transport, Mitochondrial R_COAtm equation: coa[c] <==> coa[m]
is: ENSMMUG00000030533.1
fast: false
reversible: true
name: CoA transporter
type: Reaction

131955
stoichiometry: 1.0
species: 037584
type: SpeciesReference

029679
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S
type: Species

106992
stoichiometry: 1.0
species: 020216
type: SpeciesReference

033688
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GlcNAc-alpha-1,4-Core 1_C22H37N2O15X
type: Species

047549
stoichiometry: 1.0
species: 034253
type: SpeciesReference

024378
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: S-Adenosyl-L-homocysteine_C14H20N6O5S
type: Species

126375
stoichiometry: 1.0
species: 045429
type: SpeciesReference

137133
stoichiometry: 2.0
species: 038369
type: SpeciesReference

111402
stoichiometry: 1.0
species: 024010
type: SpeciesReference

076072
stoichiometry: 1.0
species: 044416
type: SpeciesReference

085963
stoichiometry: 1.0
species: 040282
type: SpeciesReference

037353
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 2_C39H63N3O28X
type: Species

111801
stoichiometry: 8.0
species: 040813
type: SpeciesReference

930349
product: 110233
is: ENSMMUG00000017700.2
product: 110269
reactant: 110185
reactant: 110173
reactant: 110149
reactant: 110161
type: Reaction
product: 110257
reactant: 110125
reactant: 110137
notes: R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp R_GLCNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT1g equation: [g] : cs,hs_linkage + uacgam --> h + hs_pre1 + udp
fast: false
reversible: false
product: 110197
product: 110245
product: 110209
product: 110221

934324
product: 150234
product: 150222
product: 150258
is: http://identifiers.org/ec-code/1.8.1.9
reactant: 150161
reactant: 150210
product: 150246
reactant: 150198
reactant: 150185
reactant: 150173
is: ENSMMUG00000012091.2
fast: false
notes: R_TRDR subsystem: Nucleotides R_TRDR equation: [c] : h + nadph + trdox --> nadp + trdrd R_TRDR2 subsystem: Miscellaneous R_TRDR2 equation: [c] : h + nadph + q10 --> nadp + q10h2 R_TRDR3 subsystem: Miscellaneous R_TRDR3 equation: [c] : h + nadh + q10 --> nad + q10h2
reversible: false
type: Reaction

145310
stoichiometry: 1.0
species: 027906
type: SpeciesReference

055778
stoichiometry: 1.0
species: 024010
type: SpeciesReference

120333
stoichiometry: 1.0
species: 045285
type: SpeciesReference

089549
stoichiometry: 1.0
species: 036908
type: SpeciesReference

096891
stoichiometry: 1.0
species: 042247
type: SpeciesReference

063658
stoichiometry: 1.0
species: 040029
type: SpeciesReference

121006
stoichiometry: 1.0
species: 025541
type: SpeciesReference

145769
stoichiometry: 2.0
species: 036305
type: SpeciesReference

100962
stoichiometry: 1.0
species: 040198
type: SpeciesReference

077833
stoichiometry: 3.0
species: 034893
type: SpeciesReference

134520
stoichiometry: 1.0
species: 030030
type: SpeciesReference

090226
stoichiometry: 1.0
species: 030175
type: SpeciesReference

038056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

075677
stoichiometry: 1.0
species: 033021
type: SpeciesReference

103849
stoichiometry: 1.0
species: 026832
type: SpeciesReference

132786
stoichiometry: 3.0
species: 033082
type: SpeciesReference

101518
stoichiometry: 1.0
species: 034363
type: SpeciesReference

052231
stoichiometry: 3.0
species: 040126
type: SpeciesReference

116002
stoichiometry: 1.0
species: 028571
type: SpeciesReference

095980
stoichiometry: 3.0
species: 034532
type: SpeciesReference

050528
stoichiometry: 1.0
species: 044585
type: SpeciesReference

047875
stoichiometry: 1.0
species: 025637
type: SpeciesReference

092076
stoichiometry: 1.0
species: 024190
type: SpeciesReference

114899
stoichiometry: 5.0
species: 023743
type: SpeciesReference

925624
reactant: 066474
type: Reaction
reactant: 066510
product: 066618
product: 066594
product: 066546
is: http://identifiers.org/ec-code/2.7.1.21
product: 066558
reactant: 066486
reactant: 066522
product: 066582
reversible: false
reactant: 066462
fast: false
is: ENSMMUG00000000029.2
product: 066534
reactant: 066498
product: 066606
product: 066570
notes: R_DURIK1m subsystem: Nucleotides R_DURIK1m equation: [m] : atp + duri --> adp + dump + h R_TMDK1 subsystem: Nucleotides R_TMDK1 equation: [c] : atp + thymd --> adp + dtmp + h R_DURIK1 subsystem: Nucleotides R_DURIK1 equation: [c] : atp + duri --> adp + dump + h R_TMDK1m subsystem: Nucleotides R_TMDK1m equation: [m] : atp + thymd --> adp + dtmp + h

054534
stoichiometry: 1.0
species: 034387
type: SpeciesReference

926645
notes: R_PAFH subsystem: Glycerophospholipid Metabolism R_PAFH equation: [c] : h2o + paf_hs --> ac + ak2lgchol_hs + h
reversible: false
reactant: 075157
is: ENSMMUG00000021893.1
is: ENSMMUG00000000655.2
type: Reaction
product: 075193
product: 075205
is: http://identifiers.org/ec-code/3.1.1.47
is: ENSMMUG00000012172.2
name: Platelet-activating factor acetylhydrolase
is: ENSMMUG00000002050.2
fast: false
is: ENSMMUG00000008412.2
reactant: 075169
is: ENSMMUG00000020524.2
product: 075181

090467
stoichiometry: 2.0
species: 026023
type: SpeciesReference

094270
stoichiometry: 2.0
species: 027121
type: SpeciesReference

082310
stoichiometry: 5.0
species: 040162
type: SpeciesReference

122195
stoichiometry: 1.0
species: 034363
type: SpeciesReference

058989
stoichiometry: 1.0
species: 038212
type: SpeciesReference

128814
stoichiometry: 3.0
species: 023635
type: SpeciesReference

053339
stoichiometry: 1.0
species: 034253
type: SpeciesReference

038598
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21
type: Species

067981
stoichiometry: 1.0
species: 034436
type: SpeciesReference

055002
stoichiometry: 4.0
species: 040789
type: SpeciesReference

151691
stoichiometry: 1.0
species: 030151
type: SpeciesReference

928554
fast: false
product: 094294
reactant: 094246
product: 094343
reactant: 094186
product: 094282
reactant: 094258
product: 094307
reactant: 094198
is: http://identifiers.org/ec-code/4.1.1.9
notes: R_MMCDm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDm equation: [m] : h + mmcoa-S --> co2 + ppcoa R_MMCDp subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDp equation: [x] : h + mmcoa-S --> co2 + ppcoa R_MMCD subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCD equation: [c] : h + mmcoa-S --> co2 + ppcoa R_MCDp subsystem: Fatty Acid Metabolism R_MCDp equation: [x] : h + malcoa --> accoa + co2 R_MCD subsystem: Fatty Acid Metabolism R_MCD equation: [c] : h + malcoa --> accoa + co2 R_MCDm subsystem: Fatty Acid Metabolism R_MCDm equation: [m] : h + malcoa --> accoa + co2
reactant: 094210
reversible: false
is: ENSMMUG00000009849.2
reactant: 094222
product: 094355
type: Reaction
product: 094319
reactant: 094161
product: 094367
is: http://identifiers.org/ec-code/4.1.1.41
product: 094270
reactant: 094173
reactant: 094234
product: 094331

105355
stoichiometry: 1.0
species: 032124
type: SpeciesReference

131558
stoichiometry: 1.0
species: 037378
type: SpeciesReference

134014
stoichiometry: 2.0
species: 024010
type: SpeciesReference

086591
stoichiometry: 2.0
species: 038875
type: SpeciesReference

142017
stoichiometry: 18.0
species: 025541
type: SpeciesReference

924028
reactant: 051674
is: http://identifiers.org/ec-code/2.7.1.3
product: 051710
reactant: 051649
reactant: 051686
reactant: 051661
product: 051746
product: 051722
notes: R_KHK3 subsystem: Galactose metabolism R_KHK3 equation: [c] : atp + tagat-D --> adp + h + tag1p-D R_KHK2 subsystem: Glyoxylate and Dicarboxylate Metabolism R_KHK2 equation: [c] : atp + xylu-D --> adp + h + xu1p-D R_KHK subsystem: Fructose and Mannose Metabolism R_KHK equation: [c] : atp + fru --> adp + f1p + h
type: Reaction
fast: false
reversible: false
product: 051734
is: ENSMMUG00000016047.2
product: 051698

088306
stoichiometry: 1.0
species: 020033
type: SpeciesReference

032064
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C88H147N2O70X
type: Species

093462
stoichiometry: 1.0
species: 022437
type: SpeciesReference

054269
stoichiometry: 2.0
species: 023962
type: SpeciesReference

064573
stoichiometry: 1.0
species: 042283
type: SpeciesReference

034605
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Hexadecanoate (n-C16:0)_C16H31O2
type: Species

138723
stoichiometry: 1.0
species: 033082
type: SpeciesReference

075375
stoichiometry: 2.0
species: 042548
type: SpeciesReference

093318
stoichiometry: 1.0
species: 026131
type: SpeciesReference

120609
stoichiometry: 1.0
species: 033263
type: SpeciesReference

118738
stoichiometry: 10.0
species: 046211
type: SpeciesReference

127741
stoichiometry: 1.0
species: 020642
type: SpeciesReference

061886
stoichiometry: 1.0
species: 020858
type: SpeciesReference

083903
stoichiometry: 1.0
species: 036149
type: SpeciesReference

929395
product: 101843
reversible: false
is: ENSMMUG00000008442.2
product: 101867
product: 101855
is: ENSMMUG00000019481.2
reactant: 101819
type: Reaction
fast: false
notes: R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e]
reactant: 101807
is: ENSMMUG00000014694.2
reactant: 101831

103621
stoichiometry: 3.0
species: 024816
type: SpeciesReference

117619
stoichiometry: 1.0
species: 021448
type: SpeciesReference

022656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: R total 2 carnitine_CO2FULLR2C7H14NO2
type: Species

065837
stoichiometry: 1.0
species: 043259
type: SpeciesReference

042656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Protoporphyrin_C34H32N4O4
type: Species

101759
stoichiometry: 1.0
species: 022498
type: SpeciesReference

129164
stoichiometry: 1.0
species: 034363
type: SpeciesReference

085866
stoichiometry: 1.0
species: 032016
type: SpeciesReference

073323
stoichiometry: 1.0
species: 042403
type: SpeciesReference

110559
stoichiometry: 1.0
species: 025372
type: SpeciesReference

131098
stoichiometry: 1.0
species: 046549
type: SpeciesReference

928842
product: 096299
notes: R_NNDPR subsystem: NAD Metabolism R_NNDPR equation: [c] : (2) h + prpp + quln --> co2 + nicrnt + ppi
reactant: 096237
type: Reaction
product: 096273
product: 096286
reversible: false
is: http://identifiers.org/ec-code/2.4.2.19
reactant: 096249
reactant: 096261
fast: false
is: ENSMMUG00000011969.2
name: nicotinate-nucleotide diphosphorylase (carboxylating)

148445
stoichiometry: 1.0
species: 036017
type: SpeciesReference

076604
stoichiometry: 4.0
species: 040102
type: SpeciesReference

025457
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Asparagine_C4H8N2O3
type: Species

119256
stoichiometry: 1.0
species: 032208
type: SpeciesReference

114779
stoichiometry: 30.0
species: 034290
type: SpeciesReference

931024
is: ENSMMUG00000031409.1
reactant: 117776
reactant: 117812
product: 117884
product: 117896
reactant: 117824
reactant: 117788
product: 117860
fast: false
type: Reaction
reversible: false
notes: R_H6MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_L equation: [r] : (0.1) dolmanp_L + m2emgacpail_hs --> (0.1) dolp_L + h + m3emgacpail_hs R_H8MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_L equation: [r] : (0.1) dolmanp_L + gpi_hs --> (0.1) dolp_L + h + m(em)3gacpail_hs R_H6MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_U equation: [r] : (0.1) dolmanp_U + m2emgacpail_hs --> (0.1) dolp_U + h + m3emgacpail_hs R_H7MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_U equation: [r] : (0.1) dolmanp_U + em2emgacpail_hs --> (0.1) dolp_U + h + mem2emgacpail_hs R_H7MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_L equation: [r] : (0.1) dolmanp_L + em2emgacpail_hs --> (0.1) dolp_L + h + mem2emgacpail_hs R_H8MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_U equation: [r] : (0.1) dolmanp_U + gpi_hs --> (0.1) dolp_U + h + m(em)3gacpail_hs
product: 117848
product: 117836
product: 117872
reactant: 117800

126857
stoichiometry: 4.0
species: 034387
type: SpeciesReference

117510
stoichiometry: 2.0
species: 034387
type: SpeciesReference

051084
stoichiometry: 1.0
species: 023066
type: SpeciesReference

128413
stoichiometry: 1.0
species: 027073
type: SpeciesReference

111053
stoichiometry: 1.0
species: 028388
type: SpeciesReference

020714
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _3-Methyl-2-oxobutanoate_C5H7O3
type: Species

041995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Phosphoenolpyruvate_C3H2O6P
type: Species

133869
stoichiometry: 4.0
species: 046211
type: SpeciesReference

141354
stoichiometry: 1.0
species: 020155
type: SpeciesReference

137411
stoichiometry: 2.0
species: 042680
type: SpeciesReference

105896
stoichiometry: 1.0
species: 040921
type: SpeciesReference

062391
stoichiometry: 1.0
species: 043512
type: SpeciesReference

931597
is: http://identifiers.org/ec-code/1.3.1.2
reversible: true
reactant: 123614
notes: R_DURAD2 subsystem: Pyrimidine Catabolism R_DURAD2 equation: [c] : 56dthm + nadp <==> h + nadph + thym R_DURAD subsystem: Pyrimidine Catabolism R_DURAD equation: [c] : 56dura + nadp <==> h + nadph + ura
reactant: 123626
product: 123650
is: ENSMMUG00000016137.2
product: 123674
type: Reaction
product: 123662
reactant: 123602
product: 123638
fast: false

060203
stoichiometry: 1.0
species: 026335
type: SpeciesReference

130310
stoichiometry: 1.0
species: 037766
type: SpeciesReference

110921
stoichiometry: 1.0
species: 029078
type: SpeciesReference

108631
stoichiometry: 1.0
species: 023042
type: SpeciesReference

060083
stoichiometry: 1.0
species: 040474
type: SpeciesReference

058229
stoichiometry: 25.0
species: 034363
type: SpeciesReference

040077
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

122292
stoichiometry: 1.0
species: 027061
type: SpeciesReference

123566
stoichiometry: 1.0
species: 034448
type: SpeciesReference

038309
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: alpha-Linolenoyl-CoA_C39H60N7O17P3S
type: Species

078405
stoichiometry: 1.0
species: 035556
type: SpeciesReference

058868
stoichiometry: 1.0
species: 030115
type: SpeciesReference

144970
stoichiometry: 1.0
species: 027638
type: SpeciesReference

070165
stoichiometry: 1.0
species: 035726
type: SpeciesReference

043283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S
type: Species

933532
reactant: 141584
product: 141608
is: ENSMMUG00000005648.1
reversible: false
reactant: 141596
fast: false
product: 141632
product: 141620
type: Reaction
notes: R_GLNS subsystem: Glutamate metabolism R_GLNS equation: [c] : atp + glu-L + nh4 --> adp + gln-L + h + pi
is: ENSMMUG00000022884.2
reactant: 141572
name: glutamine synthetase
is: http://identifiers.org/ec-code/6.3.1.2
product: 141644

148141
stoichiometry: 1.0
species: 026518
type: SpeciesReference

087389
stoichiometry: 2.0
species: 040813
type: SpeciesReference

096076
stoichiometry: 1.0
species: 019459
type: SpeciesReference

092366
stoichiometry: 1.0
species: 034725
type: SpeciesReference

136915
stoichiometry: 1.0
species: 038369
type: SpeciesReference

074843
stoichiometry: 1.0
species: 034363
type: SpeciesReference

025757
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Bilirubin monoglucuronide_C39H44N4O12
type: Species

927870
product: 086266
product: 086254
product: 086230
reactant: 086170
product: 086278
product: 086242
product: 086218
type: Reaction
reactant: 086157
reactant: 086194
reversible: false
reactant: 086145
notes: R_H6_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ETer equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H3ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3ETer equation: [r] : m2gacpail_hs + pe_hs --> dag_hs + memgacpail_hs R_H4ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ETer equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + m2emgacpail_hs R_H7_APOS_ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_ETer equation: [r] : emem2gacpail_hs + pe_hs --> dag_hs + gpi_hs R_H2ETer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H2ETer equation: [r] : mgacpail_hs + pe_hs --> dag_hs + emgacpail_hs
reactant: 086182
reactant: 086206
is: ENSMMUG00000002204.2
fast: false

118028
stoichiometry: 1.0
species: 027230
type: SpeciesReference

086713
stoichiometry: 1.0
species: 038754
type: SpeciesReference

055368
stoichiometry: 1.0
species: 041790
type: SpeciesReference

098668
stoichiometry: 1.0
species: 038212
type: SpeciesReference

049804
stoichiometry: 1.0
species: 030941
type: SpeciesReference

085059
stoichiometry: 1.0
species: 033978
type: SpeciesReference

027061
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _2-Amino-3-carboxymuconate semialdehyde_C7H6NO5
type: Species

021123
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _4-Aminobutanal_C4H10NO
type: Species

058530
stoichiometry: 1.0
species: 034845
type: SpeciesReference

119996
stoichiometry: 1.0
species: 029704
type: SpeciesReference

126785
stoichiometry: 1.0
species: 032440
type: SpeciesReference

131110
stoichiometry: 1.0
species: 046428
type: SpeciesReference

044125
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Selenophosphate_H2O3PSe
type: Species

152174
stoichiometry: 1.0
species: 044507
type: SpeciesReference

089440
stoichiometry: 1.0
species: 036860
type: SpeciesReference

032705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GD2 (homo sapiens)_C60H101N4O33FULLRCO
type: Species

099562
stoichiometry: 1.0
species: 020191
type: SpeciesReference

130019
stoichiometry: 1.0
species: 031580
type: SpeciesReference

090007
stoichiometry: 1.0
species: 035920
type: SpeciesReference

929939
reversible: false
is: ENSMMUG00000003558.2
notes: R_CITL subsystem: Citric Acid Cycle R_CITL equation: [c] : cit --> ac + oaa
is: http://identifiers.org/ec-code/4.1.3.6
product: 105896
type: Reaction
name: Citrate lyase
reactant: 105884
product: 105908
fast: false

046367
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: UDPglucose_C15H22N2O17P2
type: Species

132365
stoichiometry: 1.0
species: 046235
type: SpeciesReference

095283
stoichiometry: 1.0
species: 042524
type: SpeciesReference

118173
stoichiometry: 1.0
species: 046476
type: SpeciesReference

151799
stoichiometry: 1.0
species: 028303
type: SpeciesReference

134820
stoichiometry: 1.0
species: 043897
type: SpeciesReference

053555
stoichiometry: 1.0
species: 028497
type: SpeciesReference

082528
stoichiometry: 1.0
species: 046743
type: SpeciesReference

095655
stoichiometry: 1.0
species: 025360
type: SpeciesReference

088630
stoichiometry: 1.0
species: 034363
type: SpeciesReference

061922
stoichiometry: 2.0
species: 042548
type: SpeciesReference

137350
stoichiometry: 2.0
species: 042956
type: SpeciesReference

069851
stoichiometry: 1.0
species: 026227
type: SpeciesReference

072914
stoichiometry: 2.0
species: 034424
type: SpeciesReference

077991
stoichiometry: 2.0
species: 034424
type: SpeciesReference

116462
stoichiometry: 3.0
species: 034303
type: SpeciesReference

143152
stoichiometry: 1.0
species: 036245
type: SpeciesReference

103317
stoichiometry: 3.0
species: 042283
type: SpeciesReference

063224
stoichiometry: 1.0
species: 040077
type: SpeciesReference

146999
stoichiometry: 2.0
species: 040150
type: SpeciesReference

051300
stoichiometry: 2.0
species: 034412
type: SpeciesReference

025673
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Betaine aldehyde_C5H12NO
type: Species

091956
stoichiometry: 1.0
species: 026011
type: SpeciesReference

057083
stoichiometry: 1.0
species: 043801
type: SpeciesReference

031315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Fe3+_Fe
type: Species

112284
stoichiometry: 1.0
species: 024034
type: SpeciesReference

146696
stoichiometry: 1.0
species: 044479
type: SpeciesReference

114335
stoichiometry: 1.0
species: 033493
type: SpeciesReference

069538
stoichiometry: 8.0
species: 034290
type: SpeciesReference

042812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Progesterone_C21H30O2
type: Species

057371
stoichiometry: 1.0
species: 033966
type: SpeciesReference

144631
stoichiometry: 3.0
species: 034339
type: SpeciesReference

054954
stoichiometry: 1.0
species: 025288
type: SpeciesReference

089197
stoichiometry: 1.0
species: 043861
type: SpeciesReference

061178
stoichiometry: 1.0
species: 041006
type: SpeciesReference

020325
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: _3',5'-Cyclic GMP_C10H11N5O7P
type: Species

133317
stoichiometry: 1.0
species: 041006
type: SpeciesReference

138506
stoichiometry: 1.0
species: 040535
type: SpeciesReference

023743
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: N-Acetylneuraminate_C11H18NO9
type: Species

080204
stoichiometry: 1.0
species: 043632
type: SpeciesReference

106295
stoichiometry: 1.0
species: 025601
type: SpeciesReference

125025
stoichiometry: 1.0
species: 026275
type: SpeciesReference

124869
stoichiometry: 2.0
species: 036173
type: SpeciesReference

022352
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-2-Aminoadipate 6-semialdehyde_C6H11NO3
type: Species

092294
stoichiometry: 1.0
species: 038080
type: SpeciesReference

932173
fast: false
reactant: 128704
reactant: 128716
product: 128728
notes: R_CGLYt3_LPAREN_2_RPAREN_ subsystem: Transport, Extracellular R_CGLYt3_LPAREN_2_RPAREN_ equation: cgly[e] + (2) h[e] --> cgly[c] + (2) h[c]
type: Reaction
product: 128741
name: Cys-Gly transport in via proton symport
is: ENSMMUG00000001049.2
reversible: false

108342
stoichiometry: 1.0
species: 044778
type: SpeciesReference

083097
stoichiometry: 1.0
species: 030090
type: SpeciesReference

128741
stoichiometry: 2.0
species: 034363
type: SpeciesReference

036980
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 27_C205H328N14O171S8X
type: Species

929179
modifier: 100189
is: http://identifiers.org/ec-code/1.1.1.78
modifier: 100092
reactant: 099959
is: http://identifiers.org/ec-code/1.2.1.49
product: 100056
modifier: 100177
notes: R_ALCD22_D subsystem: Pyruvate Metabolism R_ALCD22_D equation: [c] : lald-D + nad --> h + mthgxl + nadh R_34DHOXPEGOX subsystem: Tyrosine metabolism R_34DHOXPEGOX equation: [c] : 34dhmald + h + nadh <==> 34dhoxpeg + nad R_ALCD1 subsystem: Miscellaneous R_ALCD1 equation: [c] : meoh + nad <==> fald + h + nadh R_ALCD2if subsystem: Glycolysis/Gluconeogenesis R_ALCD2if equation: [c] : etoh + nad --> acald + h + nadh R_ALCD21_D subsystem: Pyruvate Metabolism R_ALCD21_D equation: [c] : 12ppd-R + nad --> h + lald-D + nadh R_ALCD22_L subsystem: Pyruvate Metabolism R_ALCD22_L equation: [c] : lald-L + nad --> h + mthgxl + nadh R_LALDO subsystem: Pyruvate Metabolism R_LALDO equation: [c] : gthrd + lald-D + nad <==> h + lgt-S + nadh R_ALCD21_L subsystem: Pyruvate Metabolism R_ALCD21_L equation: [c] : 12ppd-S + nad --> h + lald-L + nadh R_FALDH subsystem: Tyrosine metabolism R_FALDH equation: [c] : fald + gthrd + nad <==> Sfglutth + h + nadh
modifier: 100152
is: ENSMMUG00000014993.2
modifier: 100068
modifier: 100116
reactant: 099983
is: ENSMMUG00000006184.2
reactant: 099923
reactant: 099971
product: 100044
product: 100020
product: 100008
is: ENSMMUG00000003552.2
is: http://identifiers.org/ec-code/1.1.1.1
product: 100032
product: 099995
is: http://identifiers.org/ec-code/1.2.1.1
modifier: 100080
modifier: 100128
reactant: 099947
modifier: 100165
modifier: 100140
type: Reaction
reversible: false
modifier: 100104
reactant: 099935
fast: false

030018
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10
type: Species

026275
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Carbamoyl phosphate_CH2NO5P
type: Species

081779
stoichiometry: 1.0
species: 040198
type: SpeciesReference

058011
stoichiometry: 1.0
species: 043428
type: SpeciesReference

116885
stoichiometry: 1.0
species: 034375
type: SpeciesReference

067825
stoichiometry: 4.0
species: 042283
type: SpeciesReference

923824
product: 049731
reactant: 049719
notes: R_PGISr subsystem: Eicosanoid Metabolism R_PGISr equation: [r] : prostgh2 <==> prostgi2
is: ENSMMUG00000021692.2
is: http://identifiers.org/ec-code/5.3.99.4
fast: false
reversible: true
name: Prostaglandin I2 synthase
type: Reaction

094838
stoichiometry: 1.0
species: 042283
type: SpeciesReference

136278
stoichiometry: 1.0
species: 040077
type: SpeciesReference

071559
stoichiometry: 2.0
species: 040017
type: SpeciesReference

930621
is: ENSMMUG00000016171.2
reactant: 112995
product: 113055
reactant: 113007
is: http://identifiers.org/ec-code/2.4.1.11
notes: R_GLGNS1 subsystem: Starch and Sucrose Metabolism R_GLGNS1 equation: [c] : ggn + (3) udpg --> glygn1 + (3) h + (3) udp R_GGNG subsystem: Starch and Sucrose Metabolism R_GGNG equation: [c] : Tyr-ggn + (8) udpg --> ggn + (8) h + (8) udp
product: 113043
is: ENSMMUG00000003932.2
reactant: 113019
fast: false
product: 113067
is: ENSMMUG00000003911.2
reversible: false
product: 113031
is: ENSMMUG00000005521.2
type: Reaction

107558
stoichiometry: 1.0
species: 030880
type: SpeciesReference

093534
stoichiometry: 1.0
species: 044174
type: SpeciesReference

045501
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Thiamin monophosphate_C12H16N4O4PS
type: Species

096927
stoichiometry: 1.0
species: 042848
type: SpeciesReference

051649
stoichiometry: 1.0
species: 047381
type: SpeciesReference

134976
stoichiometry: 1.0
species: 023914
type: SpeciesReference

089319
stoichiometry: 1.0
species: 032196
type: SpeciesReference

100530
stoichiometry: 1.0
species: 020289
type: SpeciesReference

109586
stoichiometry: 1.0
species: 028376
type: SpeciesReference

037645
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
type: Species

067403
stoichiometry: 1.0
species: 034387
type: SpeciesReference

150701
stoichiometry: 3.0
species: 028303
type: SpeciesReference

926309
product: 072199
type: Reaction
product: 072211
reactant: 072175
reactant: 072150
reactant: 072187
reactant: 072162
reversible: false
reactant: 072138
is: ENSMMUG00000004411.2
fast: false
notes: R_P4507B11r subsystem: Bile Acid Biosynthesis R_P4507B11r equation: [r] : h + nadph + o2 + xol25oh --> h2o + nadp + xoltri25 R_P4507B12r subsystem: Bile Acid Biosynthesis R_P4507B12r equation: [r] : h + nadph + o2 + xol27oh --> h2o + nadp + xoltri27
product: 072235
product: 072223

084011
stoichiometry: 1.0
species: 034063
type: SpeciesReference

122953
stoichiometry: 1.0
species: 034303
type: SpeciesReference

090684
stoichiometry: 1.0
species: 044573
type: SpeciesReference

037790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Lactaldehyde_C3H6O2
type: Species

083831
stoichiometry: 1.0
species: 028644
type: SpeciesReference

097912
stoichiometry: 1.0
species: 042620
type: SpeciesReference

925264
product: 063115
reactant: 062982
is: ENSMMUG00000014783.2
reactant: 062946
product: 063066
reactant: 062994
reactant: 062958
product: 063054
fast: false
product: 063127
product: 063030
reversible: false
product: 063103
product: 063090
product: 063078
reactant: 063018
type: Reaction
is: http://identifiers.org/ec-code/2.8.2.17
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T24g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T24g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5b + h + pap R_S6T20g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T20g equation: [g] : cs_c_pre3 + paps --> cspg_c + h + pap R_S6T19g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T19g equation: [g] : cs_pre + (2) paps --> cs_c,d,e_pre1 + (2) h + (2) pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap R_S6T21g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T21g equation: [g] : cs_d_pre4 + paps --> cs_d_pre5 + h + pap
product: 063042
reactant: 063006
reactant: 062970
reactant: 062934

074423
stoichiometry: 1.0
species: 031423
type: SpeciesReference

040644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Norepinephrine_C8H12NO3
type: Species

932979
product: 136459
reversible: false
product: 136471
is: http://identifiers.org/ec-code/4.2.1.46
type: Reaction
notes: R_TDPGDH subsystem: Nucleotide Sugar Metabolism R_TDPGDH equation: [c] : dtdpglu --> dtdp4d6dg + h2o
fast: false
reactant: 136447
is: ENSMMUG00000013063.2
name: dTDPglucose 4,6-dehydratase

934480
type: Reaction
is: ENSMMUG00000018155.2
product: 151787
is: ENSMMUG00000018532.2
reactant: 151763
reactant: 151751
is: ENSMMUG00000032466.1
reversible: false
is: ENSMMUG00000031292.1
product: 151775
fast: false
is: http://identifiers.org/ec-code/3.5.1.15
name: N-Acetyl-L-aspartate amidohydrolase
notes: R_NACASPAH subsystem: Alanine and Aspartate Metabolism R_NACASPAH equation: [c] : Nacasp + h2o --> ac + asp-L

021835
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: _5-Hydroxy-L-tryptophan_C11H12N2O3
type: Species

102048
stoichiometry: 1.0
species: 022933
type: SpeciesReference

039547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _1D-myo-Inositol 1,3,4-trisphosphate_C6H9O15P3
type: Species

139230
stoichiometry: 2.0
species: 038574
type: SpeciesReference

136049
stoichiometry: 1.0
species: 038803
type: SpeciesReference

140943
stoichiometry: 8.0
species: 034363
type: SpeciesReference

142994
stoichiometry: 5.0
species: 034363
type: SpeciesReference

043343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Putrescine_C4H14N2
type: Species

931477
product: 122424
reversible: false
product: 122436
notes: R_MALTly subsystem: Starch and Sucrose Metabolism R_MALTly equation: [l] : h2o + malt --> (2) glc-D R_MLTG1ly subsystem: Starch and Sucrose Metabolism R_MLTG1ly equation: [l] : h2o + malttr --> glc-D + malt
fast: false
is: http://identifiers.org/ec-code/3.2.1.20
is: ENSMMUG00000009589.2
reactant: 122400
reactant: 122412
reactant: 122388
type: Reaction

121223
stoichiometry: 2.0
species: 034327
type: SpeciesReference

135757
stoichiometry: 1.0
species: 031001
type: SpeciesReference

110776
stoichiometry: 2.0
species: 040390
type: SpeciesReference

132906
stoichiometry: 1.0
species: 034063
type: SpeciesReference

119560
stoichiometry: 1.0
species: 025288
type: SpeciesReference

028981
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: all trans Decaprenyl diphosphate_C50H81O7P2
type: Species

134231
stoichiometry: 1.0
species: 023078
type: SpeciesReference

928338
reactant: 091009
product: 091070
reversible: false
product: 091058
fast: false
product: 091046
notes: R_ST3GAL61g subsystem: Blood Group Biosynthesis R_ST3GAL61g equation: [g] : cmpacna + gal14acglcgalgluside_hs --> acngal14acglcgalgluside_hs + cmp + h R_ST3GAL62g subsystem: Blood Group Biosynthesis R_ST3GAL62g equation: [g] : cmpacna + galacglcgal14acglcgalgluside_hs --> acngalacglcgal14acglcgalgluside_hs + cmp + h
reactant: 091021
type: Reaction
product: 091082
reactant: 091033
is: ENSMMUG00000013429.2

066017
stoichiometry: 1.0
species: 025637
type: SpeciesReference

097095
stoichiometry: 1.0
species: 024853
type: SpeciesReference

034821
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: hexacosanoyl carnitine_C33H65NO4
type: Species

044441
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

093895
stoichiometry: 8.0
species: 040017
type: SpeciesReference

928626
type: Reaction
is: ENSMMUG00000022536.2
product: 094802
is: ENSMMUG00000022535.2
notes: R_FBP26 subsystem: Fructose and Mannose Metabolism R_FBP26 equation: [c] : f26bp + h2o --> f6p + pi R_FBP subsystem: Glycolysis/Gluconeogenesis R_FBP equation: [c] : fdp + h2o --> f6p + pi
reactant: 094753
reversible: false
is: http://identifiers.org/ec-code/3.1.3.46
reactant: 094765
product: 094789
is: http://identifiers.org/ec-code/3.1.3.11
fast: false
reactant: 094777

148879
stoichiometry: 1.0
species: 033628
type: SpeciesReference

138809
stoichiometry: 1.0
species: 019634
type: SpeciesReference

034088
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: GTP_C10H12N5O14P3
type: Species

078838
stoichiometry: 1.0
species: 025541
type: SpeciesReference

120189
stoichiometry: 1.0
species: 022656
type: SpeciesReference

058446
stoichiometry: 1.0
species: 034179
type: SpeciesReference

104909
stoichiometry: 8.0
species: 032838
type: SpeciesReference

087691
stoichiometry: 1.0
species: 028086
type: SpeciesReference

113235
stoichiometry: 1.0
species: 021062
type: SpeciesReference

128970
stoichiometry: 1.0
species: 038803
type: SpeciesReference

933988
product: 147599
type: Reaction
reactant: 147563
reactant: 147587
notes: R_SQLSr subsystem: Cholesterol Metabolism R_SQLSr equation: [r] : (2) frdp + h + nadph --> nadp + (2) ppi + sql
product: 147623
product: 147611
is: http://identifiers.org/ec-code/2.5.1.21
reversible: false
reactant: 147575
is: ENSMMUG00000019211.2
name: Squalene synthase
fast: false

926081
reactant: 070598
reactant: 070610
type: Reaction
product: 070646
reversible: true
reactant: 070574
product: 070682
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c]
reactant: 070622
product: 070670
reactant: 070586
is: ENSMMUG00000010121.2
reactant: 070634
fast: false
product: 070658
product: 070707
product: 070694

050673
stoichiometry: 3.0
species: 039200
type: SpeciesReference

081455
stoichiometry: 1.0
species: 046827
type: SpeciesReference

038766
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

077352
stoichiometry: 1.0
species: 023162
type: SpeciesReference

089886
stoichiometry: 1.0
species: 041982
type: SpeciesReference

127207
stoichiometry: 12.0
species: 034532
type: SpeciesReference

024598
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Alanine_C3H7NO2
type: Species

036703
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 8_C194H311N13O171S10
type: Species

025975
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Butyrate (n-C4:0)_C4H7O2
type: Species

087811
stoichiometry: 1.0
species: 029498
type: SpeciesReference

066678
stoichiometry: 1.0
species: 039402
type: SpeciesReference

046587
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Uracil_C4H4N2O2
type: Species

062970
stoichiometry: 8.0
species: 041778
type: SpeciesReference

021546
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _5alpha-Dihydrotestosterone_C19H30O2
type: Species

049249
stoichiometry: 2.0
species: 024010
type: SpeciesReference

113765
stoichiometry: 1.0
species: 036776
type: SpeciesReference

109117
stoichiometry: 1.0
species: 035981
type: SpeciesReference

079142
stoichiometry: 1.0
species: 034881
type: SpeciesReference

121848
stoichiometry: 1.0
species: 034436
type: SpeciesReference

104295
stoichiometry: 1.0
species: 045309
type: SpeciesReference

107823
stoichiometry: 1.0
species: 044717
type: SpeciesReference

115188
stoichiometry: 1.0
species: 036533
type: SpeciesReference

076471
stoichiometry: 1.0
species: 046343
type: SpeciesReference

927233
product: 079830
type: Reaction
reversible: false
product: 079842
notes: R_LPCOXp subsystem: Lysine Metabolism R_LPCOXp equation: [x] : Lpipecol + o2 --> h + h2o2 + thp2c R_SARCOXp subsystem: Glycine, Serine, and Threonine Metabolism R_SARCOXp equation: [x] : h2o + o2 + sarcs --> fald + gly + h2o2
is: ENSMMUG00000009937.2
product: 079854
reactant: 079782
fast: false
product: 079866
reactant: 079806
is: http://identifiers.org/ec-code/1.5.3.7
reactant: 079794
reactant: 079770
product: 079818
is: http://identifiers.org/ec-code/1.5.3.1

039020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Malonyl-CoA_C24H33N7O19P3S
type: Species

094319
stoichiometry: 1.0
species: 042524
type: SpeciesReference

141572
stoichiometry: 1.0
species: 025541
type: SpeciesReference

040306
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Nicotinamide adenine dinucleotide phosphate - reduced_C21H26N7O17P3
type: Species

115700
stoichiometry: 1.0
species: 038538
type: SpeciesReference

030345
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dUDP_C9H11N2O11P2
type: Species

082757
stoichiometry: 1.0
species: 034363
type: SpeciesReference

092582
stoichiometry: 1.0
species: 022728
type: SpeciesReference

137990
stoichiometry: 1.0
species: 042572
type: SpeciesReference

130589
stoichiometry: 2.0
species: 040426
type: SpeciesReference

138290
stoichiometry: 1.0
species: 030030
type: SpeciesReference

133149
stoichiometry: 1.0
species: 028607
type: SpeciesReference

042500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Porphobilinogen_C10H13N2O4
type: Species

148227
stoichiometry: 2.0
species: 034253
type: SpeciesReference

035061
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: heptadecanoyl carnitine_C24H47NO4
type: Species

110101
stoichiometry: 2.0
species: 040198
type: SpeciesReference

091740
stoichiometry: 1.0
species: 040270
type: SpeciesReference

098176
stoichiometry: 1.0
species: 021859
type: SpeciesReference

077569
stoichiometry: 1.0
species: 040644
type: SpeciesReference

121114
stoichiometry: 1.0
species: 028644
type: SpeciesReference

148987
stoichiometry: 1.0
species: 027398
type: SpeciesReference

110885
stoichiometry: 1.0
species: 046513
type: SpeciesReference

028872
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: trans-Dodec-2-enoyl-CoA_C33H52N7O17P3S
type: Species

107244
stoichiometry: 1.0
species: 034253
type: SpeciesReference

100250
stoichiometry: 4.0
species: 034399
type: SpeciesReference

044331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Sulfate_O4S
type: Species

072223
stoichiometry: 2.0
species: 040246
type: SpeciesReference

059617
stoichiometry: 1.0
species: 045261
type: SpeciesReference

137785
stoichiometry: 1.0
species: 043127
type: SpeciesReference

039438
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (R)-Mevalonate_C6H11O4
type: Species

141052
stoichiometry: 1.0
species: 025963
type: SpeciesReference

118462
stoichiometry: 3.0
species: 046755
type: SpeciesReference

052399
stoichiometry: 1.0
species: 020714
type: SpeciesReference

040753
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Nervonyl carnitine_C31H59NO4
type: Species

034713
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
type: Species

102157
stoichiometry: 1.0
species: 027145
type: SpeciesReference

143597
stoichiometry: 1.0
species: 023466
type: SpeciesReference

077001
stoichiometry: 1.0
species: 024997
type: SpeciesReference

094427
stoichiometry: 4.0
species: 040150
type: SpeciesReference

102807
stoichiometry: 2.0
species: 026795
type: SpeciesReference

053627
stoichiometry: 2.0
species: 034253
type: SpeciesReference

102897
stoichiometry: 1.0
species: 035993
type: SpeciesReference

048007
stoichiometry: 27.0
species: 034363
type: SpeciesReference

086157
stoichiometry: 1.0
species: 038622
type: SpeciesReference

143945
stoichiometry: 1.0
species: 034363
type: SpeciesReference

059049
stoichiometry: 1.0
species: 044609
type: SpeciesReference

065717
stoichiometry: 1.0
species: 036872
type: SpeciesReference

099983
stoichiometry: 1.0
species: 037766
type: SpeciesReference

114551
stoichiometry: 1.0
species: 027145
type: SpeciesReference

019913
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _2-Carboxy-2,3-dihydro-5,6-dihydroxyindole_C9H8NO4
type: Species

929287
reactant: 100842
reactant: 100830
name: Adenosine monophosphate deaminase
is: ENSMMUG00000016253.2
type: Reaction
fast: false
product: 100866
product: 100854
is: ENSMMUG00000001978.2
is: ENSMMUG00000005820.2
reactant: 100818
notes: R_AMPDA subsystem: Nucleotides R_AMPDA equation: [c] : amp + h + h2o --> imp + nh4
reversible: false

122097
stoichiometry: 1.0
species: 031351
type: SpeciesReference

046283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: UDP_C9H11N2O12P2
type: Species

078947
stoichiometry: 1.0
species: 044077
type: SpeciesReference

079298
stoichiometry: 1.0
species: 022099
type: SpeciesReference

124314
stoichiometry: 1.0
species: 046391
type: SpeciesReference

088052
stoichiometry: 1.0
species: 022425
type: SpeciesReference

121416
stoichiometry: 4.0
species: 034363
type: SpeciesReference

077242
stoichiometry: 2.0
species: 042283
type: SpeciesReference

931369
name: triose-phosphate isomerase
is: ENSMMUG00000004310.2
is: http://identifiers.org/ec-code/5.3.1.1
reversible: true
reactant: 121812
product: 121824
is: ENSMMUG00000005194.2
notes: R_TPI subsystem: Glycolysis/Gluconeogenesis R_TPI equation: [c] : dhap <==> g3p
type: Reaction
fast: false

074579
stoichiometry: 1.0
species: 044113
type: SpeciesReference

114407
stoichiometry: 7.0
species: 032911
type: SpeciesReference

142644
stoichiometry: 1.0
species: 040246
type: SpeciesReference

052459
stoichiometry: 1.0
species: 035714
type: SpeciesReference

098020
stoichiometry: 1.5
species: 040017
type: SpeciesReference

044657
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: stearidonyl coenzyme A_C39H58N7O17P3S
type: Species

029801
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

925672
is: ENSMMUG00000008502.2
fast: false
product: 067292
product: 067316
type: Reaction
notes: R_AGPSx subsystem: Glycerophospholipid Metabolism R_AGPSx equation: [x] : adhap_hs + alkylR1oh --> Rtotal + akdhap_hs + h
reactant: 067281
name: alkylglycerone phosphate synthase
reactant: 067268
is: http://identifiers.org/ec-code/2.5.1.26
product: 067304
reversible: false

132040
stoichiometry: 1.0
species: 036872
type: SpeciesReference

103994
stoichiometry: 1.0
species: 036113
type: SpeciesReference

056708
stoichiometry: 1.0
species: 034412
type: SpeciesReference

031205
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2
type: Species

087968
stoichiometry: 1.0
species: 026953
type: SpeciesReference

038875
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X
type: Species

107931
stoichiometry: 3.0
species: 041970
type: SpeciesReference

095547
stoichiometry: 2.0
species: 032850
type: SpeciesReference

105788
stoichiometry: 1.0
species: 034412
type: SpeciesReference

927389
product: 081791
type: Reaction
product: 081815
reactant: 081779
reversible: false
product: 081827
is: ENSMMUG00000002400.2
fast: false
product: 081803
reactant: 081767
notes: R_DHCRD1 subsystem: Sphingolipid Metabolism R_DHCRD1 equation: [c] : dhcrm_hs + nadp --> crm_hs + h + nadph R_DHCRD2 subsystem: Sphingolipid Metabolism R_DHCRD2 equation: [c] : dhcrm_hs + fad --> crm_hs + fadh2
reactant: 081755

039176
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: D-Mannose_C6H12O6
type: Species

086434
stoichiometry: 1.0
species: 035435
type: SpeciesReference

070056
stoichiometry: 2.0
species: 033082
type: SpeciesReference

039237
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2
type: Species

925949
type: Reaction
reactant: 069779
product: 069839
is: ENSMMUG00000002436.2
fast: false
reactant: 069803
is: http://identifiers.org/ec-code/2.7.7.15
product: 069827
reversible: false
notes: R_CHLP subsystem: Glycerophospholipid Metabolism R_CHLP equation: [c] : cholp + h2o --> chol + pi R_ETHP subsystem: Glycerophospholipid Metabolism R_ETHP equation: [c] : ethamp + h2o --> etha + pi
reactant: 069791
product: 069815

140725
stoichiometry: 1.0
species: 033906
type: SpeciesReference

019537
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: (S)-Propane-1,2-diol_C3H8O2
type: Species

075217
stoichiometry: 1.0
species: 035581
type: SpeciesReference

148336
stoichiometry: 1.0
species: 035944
type: SpeciesReference

080082
stoichiometry: 1.0
species: 027193
type: SpeciesReference

059903
stoichiometry: 1.0
species: 024561
type: SpeciesReference

091631
stoichiometry: 1.0
species: 025541
type: SpeciesReference

096347
stoichiometry: 2.0
species: 024365
type: SpeciesReference

090853
stoichiometry: 103.0
species: 040162
type: SpeciesReference

033529
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})_C18H31O16X
type: Species

149725
stoichiometry: 1.0
species: 034363
type: SpeciesReference

933387
product: 139713
reactant: 139641
fast: false
reversible: false
notes: R_CLI2tex subsystem: Transport, Extracellular R_CLI2tex equation: cl[e] + (2) i[c] --> cl[c] + (2) i[e] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e] R_CLFORtex subsystem: Transport, Extracellular R_CLFORtex equation: cl[e] + (2) for[c] --> cl[c] + (2) for[e]
reactant: 139665
type: Reaction
product: 139701
reactant: 139677
is: ENSMMUG00000019125.2
product: 139725
reactant: 139653
product: 139689

929071
type: Reaction
notes: R_PMI1346PHn subsystem: Inositol Phosphate Metabolism R_PMI1346PHn equation: [n] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI12346PHn subsystem: Inositol Phosphate Metabolism R_PMI12346PHn equation: [n] : h2o + ppmi12346p --> h + minohp + pi
product: 097972
reactant: 097912
is: http://identifiers.org/ec-code/3.6.1.52
product: 097936
reversible: false
product: 097960
reactant: 097924
fast: false
reactant: 097900
product: 097948
is: ENSMMUG00000014730.2

135867
stoichiometry: 2.0
species: 031339
type: SpeciesReference

109718
stoichiometry: 2.0
species: 042596
type: SpeciesReference

137881
stoichiometry: 1.0
species: 023562
type: SpeciesReference

130698
stoichiometry: 1.0
species: 042283
type: SpeciesReference

071753
stoichiometry: 1.0
species: 024513
type: SpeciesReference

091203
stoichiometry: 1.0
species: 036920
type: SpeciesReference

140835
stoichiometry: 1.0
species: 025915
type: SpeciesReference

119414
stoichiometry: 1.0
species: 035581
type: SpeciesReference

074999
stoichiometry: 2.0
species: 026953
type: SpeciesReference

104186
stoichiometry: 1.0
species: 040102
type: SpeciesReference

081347
stoichiometry: 1.0
species: 030941
type: SpeciesReference

052182
stoichiometry: 1.0
species: 038984
type: SpeciesReference

125278
stoichiometry: 1.0
species: 033275
type: SpeciesReference

021943
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: (R)-5-Phosphomevalonate_C6H10O7P
type: Species

932401
notes: R_UGALNACter subsystem: Transport, Endoplasmic Reticular R_UGALNACter equation: udpacgal[c] + ump[r] <==> udpacgal[r] + ump[c] R_UDPGLCAter subsystem: Transport, Endoplasmic Reticular R_UDPGLCAter equation: udpglcur[r] + ump[c] <==> udpglcur[c] + ump[r]
reactant: 131122
is: ENSMMUG00000000645.1
reactant: 131110
product: 131134
product: 131170
type: Reaction
product: 131158
product: 131146
reversible: true
reactant: 131086
fast: false
reactant: 131098

113175
stoichiometry: 1.0
species: 032899
type: SpeciesReference

048911
stoichiometry: 1.0
species: 033396
type: SpeciesReference

047093
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _7alpha-Hydroxy-5beta-cholestan-3-one_C27H46O2
type: Species

064115
stoichiometry: 1.0
species: 021099
type: SpeciesReference

061022
stoichiometry: 1.0
species: 034581
type: SpeciesReference

069201
stoichiometry: 1.0
species: 025251
type: SpeciesReference

022015
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

039800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: beta-1,4-mannose-N-acetylglucosamine_C14H25NO11
type: Species

052870
stoichiometry: 1.0
species: 041705
type: SpeciesReference

033239
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Glyoxylate_C2H1O3
type: Species

093955
stoichiometry: 1.0
species: 019598
type: SpeciesReference

131267
stoichiometry: 1.0
species: 037609
type: SpeciesReference

044234
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-sulfolactate_C3H4O6S
type: Species

067619
stoichiometry: 1.0
species: 040198
type: SpeciesReference

133428
stoichiometry: 2.0
species: 040306
type: SpeciesReference

052036
stoichiometry: 1.0
species: 030807
type: SpeciesReference

069647
stoichiometry: 7.0
species: 033009
type: SpeciesReference

020033
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _2-Hydroxyphenylacetate_C8H7O3
type: Species

123001
stoichiometry: 1.0
species: 040270
type: SpeciesReference

098777
stoichiometry: 1.0
species: 026929
type: SpeciesReference

930777
modifier: 115272
modifier: 115406
reactant: 114767
modifier: 115285
reactant: 114611
modifier: 115236
reactant: 114599
type: Reaction
notes: R_SIAASE3ly subsystem: Keratan sulfate degradation R_SIAASE3ly equation: [l] : h2o + ksii_core2 --> acnam + ksii_core2_deg1 R_LACZly subsystem: Galactose metabolism R_LACZly equation: [l] : h2o + lcts --> gal + glc-D R_GALASE5ly subsystem: Keratan sulfate degradation R_GALASE5ly equation: [l] : h2o + ksi_deg11 --> gal + ksi_deg12 R_GALASE1ly subsystem: N-Glycan Degradation R_GALASE1ly equation: [l] : (2) h2o + l2n2m2mn --> (2) gal + n2m2mn R_S6TASE9ly subsystem: Chondroitin sulfate degradation R_S6TASE9ly equation: [l] : cs_e_deg5 + h2o <==> cs_e_deg6 + h + so4 R_S6TASE25ly subsystem: Keratan sulfate degradation R_S6TASE25ly equation: [l] : h2o + ksii_core4_deg1 <==> h + ksii_core4_deg2 + so4 R_GLB1 subsystem: Sphingolipid Metabolism R_GLB1 equation: [l] : galgluside_hs + h2o --> gal + gluside_hs R_GALASE13ly subsystem: Keratan sulfate degradation R_GALASE13ly equation: [l] : h2o + ksi_deg35 --> gal + ksi_deg36 R_S6TASE10ly subsystem: Keratan sulfate degradation R_S6TASE10ly equation: [l] : h2o + ksi_deg4 <==> h + ksi_deg5 + so4 R_GALASE17ly subsystem: Keratan sulfate degradation R_GALASE17ly equation: [l] : h2o + ksii_core2_deg5 --> gal + ksii_core2_deg6 R_GALASE6ly subsystem: Keratan sulfate degradation R_GALASE6ly equation: [l] : h2o + ksi_deg14 --> gal + ksi_deg15 R_GALASE11ly subsystem: Keratan sulfate degradation R_GALASE11ly equation: [l] : h2o + ksi_deg29 --> gal + ksi_deg30 R_GALASE3ly subsystem: Keratan sulfate degradation R_GALASE3ly equation: [l] : (2) h2o + ksi_deg5 --> (2) gal + ksi_deg6 R_S6TASE5ly subsystem: Chondroitin sulfate degradation R_S6TASE5ly equation: [l] : cs_c_deg3 + h2o <==> cs_c_deg4 + h + so4 R_GALASE19ly subsystem: Keratan sulfate degradation R_GALASE19ly equation: [l] : f1a + h2o --> core6 + gal R_SIAASE2ly subsystem: Keratan sulfate degradation R_SIAASE2ly equation: [l] : h2o + ksi_deg3 --> acnam + ksi_deg4 R_S6TASE22ly subsystem: Keratan sulfate degradation R_S6TASE22ly equation: [l] : h2o + ksii_core2_deg1 <==> h + ksii_core2_deg2…
reactant: 114803
modifier: 115248
modifier: 115382
reactant: 114695
reactant: 114683
product: 115152
product: 115104
product: 114935
product: 115164
product: 115007
product: 115080
modifier: 115442
product: 114947
reactant: 114659
modifier: 115358
product: 115092
product: 115068
modifier: 115468
modifier: 115298
is: ENSMMUG00000012145.2
modifier: 115334
reactant: 114779
reactant: 114839
is: http://identifiers.org/ec-code/3.1.6.4
product: 115200
modifier: 115418
product: 115031
product: 115019
reactant: 114851
modifier: 115322
modifier: 115394
modifier: 115260
product: 115212
product: 115043
product: 114911
reactant: 114635
modifier: 115224
fast: false
is: http://identifiers.org/ec-code/3.2.1.18
modifier: 115370
product: 115056
reactant: 114719
modifier: 115310
reactant: 114755
product: 114899
reactant: 114815
is: ENSMMUG00000032286.1
is: http://identifiers.org/ec-code/3.2.1.23
reactant: 114707
reactant: 114887
reactant: 114743
reactant: 114731
modifier: 115455
product: 114995
reactant: 114875
reactant: 114863
reversible: false
reactant: 114647
is: ENSMMUG00000014011.2
is: ENSMMUG00000012430.2
reactant: 114587
reactant: 114671
reactant: 114827
product: 114971
modifier: 115430
product: 115116
product: 115176
modifier: 115346
product: 115140
product: 114983
reactant: 114791

127074
stoichiometry: 1.0
species: 030941
type: SpeciesReference

149945
stoichiometry: 2.0
species: 040150
type: SpeciesReference

924292
reactant: 054062
reactant: 054050
type: Reaction
product: 054098
reactant: 054086
notes: R_M4BET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BET2er equation: [r] : mem2emgacpail_hs + pe_hs --> dag_hs + m(em)3gacpail_hs R_H6_APOS_ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6_APOS_ET2er equation: [r] : em3gacpail_hs + pe_hs --> dag_hs + emem2gacpail_hs R_H7ET2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7ET2er equation: [r] : em2emgacpail_hs + pe_hs --> dag_hs + gpi_hs
product: 054134
reactant: 054074
fast: false
is: ENSMMUG00000017457.2
product: 054122
reversible: false
product: 054110

068488
stoichiometry: 1.0
species: 022280
type: SpeciesReference

070914
stoichiometry: 4.0
species: 034253
type: SpeciesReference

132473
stoichiometry: 1.0
species: 046452
type: SpeciesReference

041441
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2
type: Species

093040
stoichiometry: 7.0
species: 030467
type: SpeciesReference

027796
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 4_C31H49NO29S
type: Species

923620
notes: R_ATPH2e subsystem: Nucleotides R_ATPH2e equation: [e] : adp + h2o --> amp + h + pi R_ATPH1e subsystem: Nucleotides R_ATPH1e equation: [e] : atp + (2) h2o --> amp + (2) h + (2) pi
is: ENSMMUG00000029273.1
is: ENSMMUG00000013330.2
is: ENSMMUG00000004589.2
fast: false
type: Reaction
reversible: false
product: 048356
is: ENSMMUG00000011874.2
product: 048344
product: 048331
is: ENSMMUG00000005056.2
is: http://identifiers.org/ec-code/3.6.1.5
reactant: 048307
reactant: 048295
reactant: 048319

071969
stoichiometry: 1.0
species: 026191
type: SpeciesReference

927029
product: 078369
product: 078356
type: Reaction
fast: false
reactant: 078344
notes: R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp
reactant: 078320
product: 078380
reversible: false
reactant: 078307
product: 078417
reactant: 078295
product: 078393
reactant: 078332
product: 078405
is: ENSMMUG00000012329.1

139061
stoichiometry: 1.0
species: 027145
type: SpeciesReference

040873
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Superoxide anion_O2
type: Species

143261
stoichiometry: 1.0
species: 036377
type: SpeciesReference

020435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
type: Species

087535
stoichiometry: 1.0
species: 027566
type: SpeciesReference

057987
stoichiometry: 1.0
species: 040198
type: SpeciesReference

043175
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Prostaglandin I2_C20H31O5
type: Species

075952
stoichiometry: 1.0
species: 031992
type: SpeciesReference

130164
stoichiometry: 1.0
species: 037790
type: SpeciesReference

127317
stoichiometry: 1.0
species: 034253
type: SpeciesReference

096621
stoichiometry: 4.0
species: 040029
type: SpeciesReference

101095
stoichiometry: 1.0
species: 021436
type: SpeciesReference

091848
stoichiometry: 1.0
species: 024046
type: SpeciesReference

931729
product: 124797
notes: R_AGTim subsystem: Alanine and Aspartate Metabolism R_AGTim equation: [m] : ala-L + glx --> gly + pyr
is: ENSMMUG00000006301.2
is: http://identifiers.org/ec-code/2.6.1.44
reactant: 124784
reversible: false
product: 124809
name: alanine-glyoxylate transaminase (irreversible), mitochondrial
type: Reaction
is: ENSMMUG00000011903.2
fast: false
reactant: 124772

067511
stoichiometry: 1.0
species: 030783
type: SpeciesReference

107666
stoichiometry: 5.0
species: 032838
type: SpeciesReference

116110
stoichiometry: 1.0
species: 040644
type: SpeciesReference

132630
stoichiometry: 1.0
species: 034363
type: SpeciesReference

103207
stoichiometry: 1.0
species: 025541
type: SpeciesReference

104102
stoichiometry: 1.0
species: 046343
type: SpeciesReference

053772
stoichiometry: 1.0
species: 029385
type: SpeciesReference

045851
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Trehalose_C12H22O11
type: Species

031871
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: VI2Fuc-nLc6_C64H112N3O36FULLRCO
type: Species

054845
stoichiometry: 1.0
species: 030710
type: SpeciesReference

144522
stoichiometry: 1.0
species: 045273
type: SpeciesReference

084120
stoichiometry: 1.0
species: 046719
type: SpeciesReference

076315
stoichiometry: 2.0
species: 042331
type: SpeciesReference

044839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Tagatose 1-phosphate_C6H11O9P
type: Species

097299
stoichiometry: 1.0
species: 045105
type: SpeciesReference

051758
stoichiometry: 1.0
species: 042488
type: SpeciesReference

065945
stoichiometry: 7.0
species: 040789
type: SpeciesReference

095247
stoichiometry: 1.0
species: 023006
type: SpeciesReference

029090
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dGMP_C10H12N5O7P
type: Species

108498
stoichiometry: 2.0
species: 034363
type: SpeciesReference

932281
product: 129741
product: 129729
reactant: 129681
is: ENSMMUG00000003376.2
fast: false
product: 129717
product: 129693
reversible: false
reactant: 129669
type: Reaction
reactant: 129645
reactant: 129657
notes: R_GLYVESSEC subsystem: Transport, Extracellular R_GLYVESSEC equation: atp[c] + (3) gly[c] + h2o[c] --> adp[c] + (3) gly[e] + h[c] + pi[c] R_BALAVECSEC subsystem: Transport, Extracellular R_BALAVECSEC equation: (3) ala-B[c] + atp[c] + h2o[c] --> adp[c] + (3) ala-B[e] + h[c] + pi[c] R_GABAVESSEC subsystem: Transport, Extracellular R_GABAVESSEC equation: (3) 4abut[c] + atp[c] + h2o[c] --> (3) 4abut[e] + adp[c] + h[c] + pi[c]
product: 129705
reactant: 129633
product: 129753

081887
stoichiometry: 1.0
species: 032476
type: SpeciesReference

047983
stoichiometry: 1.0
species: 035969
type: SpeciesReference

066882
stoichiometry: 1.0
species: 044633
type: SpeciesReference

076194
stoichiometry: 1.0
species: 025565
type: SpeciesReference

925372
name: sulfate transport via bicarbonate countertransport
type: Reaction
reactant: 064356
product: 064368
is: ENSMMUG00000002850.2
product: 064380
reversible: false
reactant: 064344
notes: R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c]
fast: false

067727
stoichiometry: 1.0
species: 033493
type: SpeciesReference

062813
stoichiometry: 1.0
species: 027145
type: SpeciesReference

071668
stoichiometry: 1.0
species: 028509
type: SpeciesReference

021279
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _4-Maleylacetoacetate_C8H6O6
type: Species

089100
stoichiometry: 1.0
species: 021388
type: SpeciesReference

106185
stoichiometry: 1.0
species: 040150
type: SpeciesReference

125133
stoichiometry: 1.0
species: 032959
type: SpeciesReference

119838
stoichiometry: 1.0
species: 026880
type: SpeciesReference

043740
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Ribose_C5H10O5
type: Species

060541
stoichiometry: 1.0
species: 040174
type: SpeciesReference

112538
stoichiometry: 1.0
species: 032887
type: SpeciesReference

042920
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: D-Proline_C5H9NO2
type: Species

044983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Thiocyanate_CNS
type: Species

083819
stoichiometry: 10.0
species: 025577
type: SpeciesReference

090044
stoichiometry: 1.0
species: 025637
type: SpeciesReference

036125
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: ITP_C10H11N4O14P3
type: Species

147671
stoichiometry: 2.0
species: 034605
type: SpeciesReference

109477
stoichiometry: 1.0
species: 029259
type: SpeciesReference

032801
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: GDP_C10H12N5O11P2
type: Species

045405
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO
type: Species

926765
is: http://identifiers.org/ec-code/3.1.3.36
reversible: false
fast: false
product: 076121
reactant: 076109
type: Reaction
reactant: 076096
product: 076133
notes: R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi
name: phosphatidylinositol-4,5-bisphosphate 5-phosphatase
is: ENSMMUG00000008825.2

046911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: omega hydroxy hexadecanoate (n-C16:0)_C16H31O3
type: Species

020472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
type: Species

089428
stoichiometry: 1.0
species: 037184
type: SpeciesReference

925504
notes: R_NTD4 subsystem: Pyrimidine Catabolism R_NTD4 equation: [c] : cmp + h2o --> cytd + pi R_NTD2 subsystem: Pyrimidine Catabolism R_NTD2 equation: [c] : h2o + ump --> pi + uri
product: 065777
type: Reaction
reactant: 065729
reversible: false
reactant: 065741
fast: false
is: ENSMMUG00000011695.2
product: 065789
reactant: 065753
product: 065765
is: http://identifiers.org/ec-code/3.1.3.5

084374
stoichiometry: 1.0
species: 024106
type: SpeciesReference

096770
stoichiometry: 2.0
species: 033119
type: SpeciesReference

125809
stoichiometry: 1.0
species: 027990
type: SpeciesReference

046055
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: tetracosanoyl-CoA (n-C24:0CoA)_C45H78N7O17P3S
type: Species

020882
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3-Phosphohydroxypyruvate_C3H2O7P
type: Species

054509
stoichiometry: 1.0
species: 022945
type: SpeciesReference

066462
stoichiometry: 1.0
species: 030418
type: SpeciesReference

074134
stoichiometry: 1.0
species: 022510
type: SpeciesReference

129585
stoichiometry: 2.0
species: 028243
type: SpeciesReference

085722
stoichiometry: 1.0
species: 040306
type: SpeciesReference

030054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10
type: Species

111909
stoichiometry: 1.0
species: 047201
type: SpeciesReference

055632
stoichiometry: 1.0
species: 026650
type: SpeciesReference

124941
stoichiometry: 1.0
species: 025565
type: SpeciesReference

145430
stoichiometry: 1.0
species: 027796
type: SpeciesReference

104716
stoichiometry: 1.0
species: 019803
type: SpeciesReference

047730
stoichiometry: 1.0
species: 039981
type: SpeciesReference

041114
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: octadecadienoate (n-C18:2)_C18H31O2
type: Species

059193
stoichiometry: 1.0
species: 038092
type: SpeciesReference

082431
stoichiometry: 1.0
species: 028656
type: SpeciesReference

057046
stoichiometry: 1.0
species: 037645
type: SpeciesReference

038477
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Gal-Xyl-L-Ser (protein)_C11H19O9X
type: Species

930985
reversible: true
is: ENSMMUG00000001002.2
name: L-ascorbate transport via proton symport
type: Reaction
fast: false
notes: R_ASCBt4 subsystem: Transport, Extracellular R_ASCBt4 equation: ascb-L[e] + na1[e] <==> ascb-L[c] + na1[c]
product: 117570
reactant: 117546
is: ENSMMUG00000020005.2
reactant: 117558
product: 117583

150294
stoichiometry: 1.0
species: 023586
type: SpeciesReference

037958
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: w-hydroxyl leukotriene B4_C20H31O5
type: Species

029247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4
type: Species

028002
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 2_C45H66N2O49S4
type: Species

065187
stoichiometry: 1.0
species: 024525
type: SpeciesReference

099416
stoichiometry: 1.0
species: 020216
type: SpeciesReference

073058
stoichiometry: 1.0
species: 035726
type: SpeciesReference

138603
stoichiometry: 3.0
species: 040198
type: SpeciesReference

056190
stoichiometry: 1.0
species: 035860
type: SpeciesReference

060974
stoichiometry: 1.0
species: 020045
type: SpeciesReference

932137
fast: false
name: phosphogluconate dehydrogenase
product: 128401
notes: R_GND subsystem: Pentose Phosphate Pathway R_GND equation: [c] : 6pgc + nadp --> co2 + nadph + ru5p-D
reversible: false
is: http://identifiers.org/ec-code/1.1.1.44
is: ENSMMUG00000023029.2
product: 128425
is: ENSMMUG00000031723.1
product: 128413
reactant: 128389
reactant: 128377
type: Reaction

145164
stoichiometry: 1.0
species: 036546
type: SpeciesReference

081611
stoichiometry: 1.0
species: 021279
type: SpeciesReference

067764
stoichiometry: 1.0
species: 044935
type: SpeciesReference

113645
stoichiometry: 1.0
species: 025493
type: SpeciesReference

131835
stoichiometry: 1.0
species: 036920
type: SpeciesReference

042247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: phytanic acid_C20H39O2
type: Species

085095
stoichiometry: 1.0
species: 034412
type: SpeciesReference

933111
product: 137797
reactant: 137737
reactant: 137749
product: 137785
fast: false
reactant: 137761
reversible: false
reactant: 137725
product: 137773
type: Reaction
notes: R_CBR2 subsystem: Eicosanoid Metabolism R_CBR2 equation: [c] : h + nadph + prostge2 --> nadp + prostgf2 R_CBR1 subsystem: Eicosanoid Metabolism R_CBR1 equation: [c] : h + nadph + prostg1 --> nadp + prostge1
is: ENSMMUG00000020565.2

102277
stoichiometry: 1.0
species: 024658
type: SpeciesReference

033021
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Glutamine_C5H10N2O3
type: Species

059085
stoichiometry: 1.0
species: 035061
type: SpeciesReference

049395
stoichiometry: 5.0
species: 034375
type: SpeciesReference

060361
stoichiometry: 1.0
species: 029752
type: SpeciesReference

113380
stoichiometry: 11.0
species: 040162
type: SpeciesReference

033566
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GM1alpha (homo sapiens)_C55H95N3O30FULLRCO
type: Species

126255
stoichiometry: 2.0
species: 041766
type: SpeciesReference

050384
stoichiometry: 1.0
species: 045201
type: SpeciesReference

137011
stoichiometry: 1.0
species: 020057
type: SpeciesReference

085216
stoichiometry: 1.0
species: 024010
type: SpeciesReference

071246
stoichiometry: 1.0
species: 046464
type: SpeciesReference

032294
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: i-antigen_C58H102N3O32FULLRCO
type: Species

110318
stoichiometry: 4.0
species: 025541
type: SpeciesReference

123229
stoichiometry: 4.0
species: 034520
type: SpeciesReference

112983
stoichiometry: 1.0
species: 046391
type: SpeciesReference

022244
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: heptaglutamyl folate (DHF)_C49H55N13O24
type: Species

930203
notes: R_CYOOm3 subsystem: Oxidative Phosphorylation R_CYOOm3 equation: (4) focytC[m] + (7.92) h[m] + o2[m] --> (4) ficytC[m] + (4) h[c] + (1.96) h2o[m] + (0.02) o2s[m]
fast: false
is: ENSMMUG00000002837.2
is: ENSMMUG00000029774.1
reactant: 108041
is: ENSMMUG00000001767.1
is: http://identifiers.org/ec-code/1.9.3.1
is: ENSMMUG00000016278.2
is: ENSMMUG00000009730.2
is: ENSMMUG00000006763.2
is: ENSMMUG00000000165.2
is: ENSMMUG00000000455.2
is: ENSMMUG00000031143.1
is: ENSMMUG00000011677.2
name: cytochrome c oxidase, mitochondrial Complex IV
product: 108065
is: ENSMMUG00000015861.2
is: ENSMMUG00000030183.1
reversible: false
product: 108077
is: ENSMMUG00000016765.2
is: ENSMMUG00000030892.1
reactant: 108029
is: ENSMMUG00000028686.1
product: 108053
is: ENSMMUG00000014353.2
is: ENSMMUG00000031920.1
product: 108089
is: ENSMMUG00000000250.2
is: ENSMMUG00000007383.2
type: Reaction
reactant: 108017

044029
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Se-Adenosylselenomethionine_C15H23N6O5Se
type: Species

082540
stoichiometry: 1.0
species: 036137
type: SpeciesReference

150934
stoichiometry: 1.0
species: 044453
type: SpeciesReference

027314
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: coumarin_C9H6O2
type: Species

119112
stoichiometry: 1.0
species: 033918
type: SpeciesReference

147275
stoichiometry: 4.0
species: 042740
type: SpeciesReference

090104
stoichiometry: 1.0
species: 035762
type: SpeciesReference

041850
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Procollagen 5-hydroxy-L-lysine_C6H14N2O3
type: Species

118919
stoichiometry: 1.0
species: 027145
type: SpeciesReference

134664
stoichiometry: 1.0
species: 023938
type: SpeciesReference

069815
stoichiometry: 1.0
species: 031001
type: SpeciesReference

019695
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _1-alpha,25-Dihydroxyvitamin D3_C27H44O3
type: Species

077979
stoichiometry: 1.0
species: 039679
type: SpeciesReference

082867
stoichiometry: 1.0
species: 034857
type: SpeciesReference

059803
stoichiometry: 1.0
species: 020894
type: SpeciesReference

057143
stoichiometry: 1.0
species: 039945
type: SpeciesReference

058893
stoichiometry: 1.0
species: 021376
type: SpeciesReference

037232
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate II (core 2-linked), degradation product 4_C58H95N5O43SX
type: Species

033469
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Glycolate_C2H3O3
type: Species

069019
stoichiometry: 1.0
species: 024034
type: SpeciesReference

128305
stoichiometry: 4.0
species: 034375
type: SpeciesReference

924724
reactant: 057721
fast: false
type: Reaction
reversible: true
notes: R_KCC2t subsystem: Transport, Extracellular R_KCC2t equation: cl[e] + nh4[e] <==> cl[c] + nh4[c] R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]
product: 057758
product: 057746
is: ENSMMUG00000019441.2
product: 057770
reactant: 057709
is: ENSMMUG00000008491.2
reactant: 057733
is: ENSMMUG00000020935.2

117812
stoichiometry: 2.0
species: 038562
type: SpeciesReference

928963
product: 097071
type: Reaction
reactant: 097023
notes: R_GMPS2 subsystem: Nucleotides R_GMPS2 equation: [c] : atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi
reactant: 097059
reversible: false
product: 097107
name: GMP synthase
fast: false
reactant: 097035
product: 097119
product: 097095
is: ENSMMUG00000007324.2
is: http://identifiers.org/ec-code/6.3.5.2
reactant: 097047
product: 097083

062114
stoichiometry: 1.0
species: 024034
type: SpeciesReference

076725
stoichiometry: 1.0
species: 041778
type: SpeciesReference

132618
stoichiometry: 1.0
species: 023114
type: SpeciesReference

025312
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: C20:4-CoA_C41H62N7O17P3S
type: Species

078525
stoichiometry: 2.0
species: 024378
type: SpeciesReference

058674
stoichiometry: 1.0
species: 039643
type: SpeciesReference

062415
stoichiometry: 1.0
species: 041344
type: SpeciesReference

128534
stoichiometry: 2.0
species: 034436
type: SpeciesReference

054146
stoichiometry: 1.0
species: 037838
type: SpeciesReference

137556
stoichiometry: 1.0
species: 027073
type: SpeciesReference

126881
stoichiometry: 1.0
species: 033942
type: SpeciesReference

120753
stoichiometry: 3.0
species: 034339
type: SpeciesReference

021582
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8
type: Species

108911
stoichiometry: 1.0
species: 035932
type: SpeciesReference

062270
stoichiometry: 1.0
species: 029346
type: SpeciesReference

106872
stoichiometry: 1.0
species: 021859
type: SpeciesReference

130431
stoichiometry: 1.0
species: 024561
type: SpeciesReference

040330
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-Acetyl-D-glucosaminyldiphosphodolichol, human liver homolog_C1160H1898N10O120P20
type: Species

058108
stoichiometry: 1.0
species: 035896
type: SpeciesReference

050239
stoichiometry: 22.0
species: 040849
type: SpeciesReference

035799
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: L-Iduronate_C6H9O7
type: Species

150500
stoichiometry: 1.0
species: 019731
type: SpeciesReference

123590
stoichiometry: 1.0
species: 043488
type: SpeciesReference

040198
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3
type: Species

024142
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: ADPribose_C15H21N5O14P2
type: Species

110463
stoichiometry: 1.0
species: 043223
type: SpeciesReference

123445
stoichiometry: 3.0
species: 034339
type: SpeciesReference

924148
notes: R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs R_PIK3er subsystem: Inositol Phosphate Metabolism R_PIK3er equation: [r] : atp + pail_hs --> adp + h + pail3p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3Ker subsystem: Inositol Phosphate Metabolism R_PI5P3Ker equation: [r] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3Ker subsystem: Inositol Phosphate Metabolism R_PI4P3Ker equation: [r] : atp + pail4p_hs --> adp + h + pail34p_hs
product: 053014
product: 052954
product: 052990
product: 052930
reactant: 052882
reactant: 052918
product: 052978
product: 052942
product: 053038
reactant: 052870
reactant: 052845
reactant: 052906
is: http://identifiers.org/ec-code/2.7.1.137
product: 053002
reactant: 052833
is: ENSMMUG00000016563.2
reversible: false
fast: false
product: 053026
type: Reaction
reactant: 052894
reactant: 052858
product: 052966

148565
stoichiometry: 1.0
species: 025263
type: SpeciesReference

067195
stoichiometry: 1.0
species: 027278
type: SpeciesReference

079481
stoichiometry: 1.0
species: 033263
type: SpeciesReference

047441
stoichiometry: 1.0
species: 031073
type: SpeciesReference

066245
stoichiometry: 1.0
species: 032234
type: SpeciesReference

058746
stoichiometry: 1.0
species: 042283
type: SpeciesReference

106716
stoichiometry: 9.0
species: 040017
type: SpeciesReference

074819
stoichiometry: 1.0
species: 025541
type: SpeciesReference

071027
stoichiometry: 11.0
species: 032838
type: SpeciesReference

087244
stoichiometry: 2.0
species: 034387
type: SpeciesReference

141474
stoichiometry: 4.0
species: 034387
type: SpeciesReference

061742
stoichiometry: 1.0
species: 023598
type: SpeciesReference

057903
stoichiometry: 1.0
species: 022437
type: SpeciesReference

120020
stoichiometry: 1.0
species: 041211
type: SpeciesReference

103741
stoichiometry: 1.0
species: 041597
type: SpeciesReference

128958
stoichiometry: 1.0
species: 038766
type: SpeciesReference

068017
stoichiometry: 1.0
species: 034253
type: SpeciesReference

071981
stoichiometry: 1.0
species: 022051
type: SpeciesReference

086470
stoichiometry: 1.0
species: 035447
type: SpeciesReference

049535
stoichiometry: 1.0
species: 021895
type: SpeciesReference

035001
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Homovanillate_C9H9O4
type: Species

142415
stoichiometry: 1.0
species: 019325
type: SpeciesReference

040486
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Nicotinate D-ribonucleotide_C11H12NO9P
type: Species

128631
stoichiometry: 1.0
species: 031532
type: SpeciesReference

933676
type: Reaction
product: 142958
reactant: 142910
notes: R_SRTNt6_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_SRTNt6_LPAREN_2_RPAREN_r equation: (2) k[c] + (2) na1[e] + srtn[e] <==> (2) k[e] + (2) na1[c] + srtn[c]
reactant: 142922
product: 142934
reversible: true
is: ENSMMUG00000003515.2
fast: false
name: Seratonin reversible transport in via sodium symport/potassium antiport (1:2)
product: 142946
reactant: 142898

137229
stoichiometry: 1.0
species: 034387
type: SpeciesReference

075254
stoichiometry: 4.0
species: 023090
type: SpeciesReference

144209
stoichiometry: 2.0
species: 044137
type: SpeciesReference

928410
reactant: 092715
fast: false
product: 092955
product: 092907
product: 093028
reactant: 092811
product: 093016
reactant: 092775
product: 092943
type: Reaction
reactant: 092847
reactant: 092727
is: ENSMMUG00000018031.2
reactant: 092871
product: 093040
reactant: 092690
reversible: false
reactant: 092751
reactant: 092823
reactant: 092787
reactant: 092703
product: 092992
product: 092931
product: 092980
product: 092968
product: 092895
product: 093076
product: 093004
reactant: 092859
reactant: 092763
reactant: 092739
notes: R_DNDPt49m subsystem: Transport, Mitochondrial R_DNDPt49m equation: dadp[m] + dttp[c] --> dadp[c] + dttp[m] R_DNDPt22m subsystem: Transport, Mitochondrial R_DNDPt22m equation: dtdp[c] + dudp[m] --> dtdp[m] + dudp[c] R_DNDPt17m subsystem: Transport, Mitochondrial R_DNDPt17m equation: dcdp[m] + dudp[c] --> dcdp[c] + dudp[m] R_DNDPt11m subsystem: Transport, Mitochondrial R_DNDPt11m equation: dadp[c] + dgdp[m] --> dadp[m] + dgdp[c] R_DNDPt52m subsystem: Transport, Mitochondrial R_DNDPt52m equation: dctp[c] + dudp[m] --> dctp[m] + dudp[c] R_DNDPt2m subsystem: Transport, Mitochondrial R_DNDPt2m equation: atp[m] + datp[c] --> atp[c] + datp[m] R_DNDPt63m subsystem: Transport, Mitochondrial R_DNDPt63m equation: dcdp[m] + dgtp[c] --> dcdp[c] + dgtp[m] R_DNDPt47m subsystem: Transport, Mitochondrial R_DNDPt47m equation: dtdp[m] + dttp[c] --> dtdp[c] + dttp[m] R_DNDPt13m subsystem: Transport, Mitochondrial R_DNDPt13m equation: atp[m] + dadp[c] --> atp[c] + dadp[m] R_DNDPt32m subsystem: Transport, Mitochondrial R_DNDPt32m equation: atp[m] + dgdp[c] --> atp[c] + dgdp[m] R_DNDPt12m subsystem: Transport, Mitochondrial R_DNDPt12m equation: adp[m] + dadp[c] --> adp[c] + dadp[m] R_DNDPt46m subsystem: Transport, Mitochondrial R_DNDPt46m equation: dttp[c] + dudp[m] --> dttp[m] + dudp[c] R_DNDPt28m subsystem: Transport, Mitochondrial R_DNDPt28m equation: dcdp[c] + dgdp[m] --> dcdp[m] + dgdp[c] R_DNDPt60m subsystem: Transport, Mitochondrial R_DNDPt60m equation: dgtp[c] + dudp[m] --> dgtp[m] + dudp[c] R_DNDPt24m subsystem: Transport, Mitochondrial R_DNDPt24m equation: dadp[m] + dtdp[c] --> dadp[c] + dtdp[m] R_DNDPt30m subsystem: Transport, Mitochondrial R_DNDPt30m equation: adp[m] + dcdp[c] --> adp[c] + dcdp[m] R_DNDPt54m subsystem: Transport, Mitochondrial R_DNDPt54m equation: dadp[m] + dctp[c] --> dadp[c] + dctp[m] R_DNDPt29m subsystem: Transport, Mitochondrial R_DNDPt29m equation: dadp[m] + dcdp[c] --> dadp[c] + dcdp[m] R_DNDPt8m subsystem: Transport, Mitochondrial R_DNDPt8m equation: da…
reactant: 092883
product: 093064
product: 092919
product: 093052
reactant: 092835
reactant: 092799
product: 093089

117066
stoichiometry: 1.0
species: 026143
type: SpeciesReference

927485
type: Reaction
product: 082805
is: ENSMMUG00000028843.1
product: 082817
reactant: 082781
reactant: 082769
fast: false
reversible: true
reactant: 082793
product: 082830
notes: R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c] R_NAIt subsystem: Transport, Extracellular R_NAIt equation: i[e] + (2) na1[e] <==> i[c] + (2) na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]

105043
stoichiometry: 1.0
species: 031834
type: SpeciesReference

030916
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: estrone glucuronide_C24H30O8
type: Species

048151
stoichiometry: 1.0
species: 035241
type: SpeciesReference

131678
stoichiometry: 1.0
species: 037040
type: SpeciesReference

031713
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
type: Species

134158
stoichiometry: 2.0
species: 032911
type: SpeciesReference

048416
stoichiometry: 1.0
species: 040222
type: SpeciesReference

053856
stoichiometry: 3.0
species: 041754
type: SpeciesReference

114635
stoichiometry: 1.0
species: 037463
type: SpeciesReference

097815
stoichiometry: 4.0
species: 041766
type: SpeciesReference

111197
stoichiometry: 1.0
species: 028110
type: SpeciesReference

101614
stoichiometry: 1.0
species: 040354
type: SpeciesReference

094910
stoichiometry: 1.0
species: 031181
type: SpeciesReference

022510
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Protein N6,N6-dimethyl-L-lysine_C2H7X
type: Species

042091
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2
type: Species

136061
stoichiometry: 1.0
species: 038754
type: SpeciesReference

113912
stoichiometry: 1.0
species: 036932
type: SpeciesReference

070382
stoichiometry: 2.0
species: 034363
type: SpeciesReference

093991
stoichiometry: 1.0
species: 020870
type: SpeciesReference

093438
stoichiometry: 1.0
species: 024853
type: SpeciesReference

099114
stoichiometry: 5.0
species: 025541
type: SpeciesReference

073202
stoichiometry: 1.0
species: 025915
type: SpeciesReference

135929
stoichiometry: 1.0
species: 038670
type: SpeciesReference

046791
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: vaccenyl coenzyme A_C39H64N7O17P3S
type: Species

103969
stoichiometry: 1.0
species: 044742
type: SpeciesReference

052146
stoichiometry: 1.0
species: 039032
type: SpeciesReference

126990
stoichiometry: 1.0
species: 025794
type: SpeciesReference

135505
stoichiometry: 1.0
species: 035121
type: SpeciesReference

111089
stoichiometry: 2.0
species: 023974
type: SpeciesReference

141366
stoichiometry: 1.0
species: 033445
type: SpeciesReference

048838
stoichiometry: 1.0
species: 034253
type: SpeciesReference

039250
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: ({[(mannosyl),(phosphoethanolaminyl)]-dimannosyl},{phosphoethanolaminyl})-mannosyl-glucosaminyl-acylphosphatidylinositol-Protein (M4B)_C59H110N3O40P3FULLRCO2FULLR2CO2X
type: Species

110933
stoichiometry: 10.0
species: 034290
type: SpeciesReference

117607
stoichiometry: 1.0
species: 034412
type: SpeciesReference

117546
stoichiometry: 1.0
species: 040029
type: SpeciesReference

044693
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: stearidonyl carnitine_C25H41NO4
type: Species

062524
stoichiometry: 1.0
species: 024501
type: SpeciesReference

029359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Dehydroepiandrosterone_C19H28O2
type: Species

105884
stoichiometry: 1.0
species: 026771
type: SpeciesReference

020726
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: (S)-3-Methyl-2-oxopentanoate_C6H9O3
type: Species

137857
stoichiometry: 1.0
species: 046199
type: SpeciesReference

076616
stoichiometry: 1.0
species: 044803
type: SpeciesReference

119268
stoichiometry: 1.0
species: 024010
type: SpeciesReference

114743
stoichiometry: 1.0
species: 037244
type: SpeciesReference

132509
stoichiometry: 2.0
species: 034375
type: SpeciesReference

070153
stoichiometry: 1.0
species: 035750
type: SpeciesReference

023418
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Type IIIA glycolipid_C78H135N4O45FULLRCO
type: Species

928854
reactant: 096311
reactant: 096335
fast: false
product: 096383
type: Reaction
product: 096371
reversible: false
notes: R_SALMCOM2 subsystem: Tyrosine metabolism R_SALMCOM2 equation: [c] : adrnl + amet --> ahcys + h + mepi R_SALMCOM subsystem: Tyrosine metabolism R_SALMCOM equation: [c] : amet + nrpphr --> ahcys + h + normete-L
is: http://identifiers.org/ec-code/2.1.1.6
product: 096359
reactant: 096323
is: ENSMMUG00000008694.2
product: 096347

151319
stoichiometry: 1.0
species: 032669
type: SpeciesReference

035459
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 14_C79H115N5O95S10X
type: Species

044319
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Sulfate_O4S
type: Species

104379
stoichiometry: 1.0
species: 040053
type: SpeciesReference

072404
stoichiometry: 1.0
species: 042223
type: SpeciesReference

130795
stoichiometry: 2.0
species: 039849
type: SpeciesReference

137448
stoichiometry: 2.0
species: 042656
type: SpeciesReference

925961
is: http://identifiers.org/ec-code/2.5.1.17
fast: false
modifier: 069911
modifier: 069923
modifier: 069899
notes: R_CBLATm subsystem: Vitamin B12 Metabolism R_CBLATm equation: [m] : atp + cbl1 + h <==> adocbl + pppi R_CBL2tm subsystem: Transport, Mitochondrial R_CBL2tm equation: cbl2[c] --> cbl2[m]
modifier: 069887
product: 069863
type: Reaction
modifier: 069875
reversible: false
is: ENSMMUG00000005382.2
reactant: 069851

025745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Bilirubin monoglucuronide_C39H44N4O12
type: Species

130323
stoichiometry: 1.0
species: 035896
type: SpeciesReference

096088
stoichiometry: 1.0
species: 040282
type: SpeciesReference

117102
stoichiometry: 1.0
species: 030807
type: SpeciesReference

127627
stoichiometry: 1.0
species: 034303
type: SpeciesReference

933520
type: Reaction
product: 141560
product: 141547
reversible: true
is: ENSMMUG00000015605.2
reactant: 141535
is: ENSMMUG00000002520.2
is: ENSMMUG00000017100.2
notes: R_HCO3_CLt subsystem: Transport, Extracellular R_HCO3_CLt equation: cl[c] + hco3[e] <==> cl[e] + hco3[c]
is: ENSMMUG00000003723.2
fast: false
is: ENSMMUG00000020456.2
reactant: 141522
name: bicarbonate transport (Cl-/HCO3- exchange)

933075
name: picolinic acid decarboxylase
notes: R_PCLAD subsystem: Tryptophan metabolism R_PCLAD equation: [c] : cmusa + h --> am6sa + co2
product: 137556
type: Reaction
reactant: 137532
is: http://identifiers.org/ec-code/4.1.1.45
reversible: false
reactant: 137544
is: ENSMMUG00000010195.2
fast: false
product: 137568

103122
stoichiometry: 1.0
species: 033009
type: SpeciesReference

021690
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: (R)-5-Diphosphomevalonate_C6H10O10P2
type: Species

932703
product: 134399
product: 134387
reversible: false
is: ENSMMUG00000001243.2
reactant: 134351
is: http://identifiers.org/ec-code/4.6.1.1
reactant: 134339
product: 134411
reactant: 134315
product: 134375
product: 134363
fast: false
reactant: 134327
notes: R_ADNCYC subsystem: Nucleotides R_ADNCYC equation: [c] : atp --> camp + ppi R_ALOX52 subsystem: Eicosanoid Metabolism R_ALOX52 equation: [c] : 5HPET --> h2o + leuktrA4 R_ALOX5 subsystem: Eicosanoid Metabolism R_ALOX5 equation: [c] : arachd + o2 --> 5HPET
is: ENSMMUG00000029965.1
type: Reaction
is: http://identifiers.org/ec-code/1.13.11.34

084578
stoichiometry: 41.0
species: 027218
type: SpeciesReference

049647
stoichiometry: 1.0
species: 024961
type: SpeciesReference

122280
stoichiometry: 1.0
species: 040789
type: SpeciesReference

122058
stoichiometry: 1.0
species: 042007
type: SpeciesReference

025420
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Ascorbate_C6H8O6
type: Species

082020
stoichiometry: 1.0
species: 028956
type: SpeciesReference

127909
stoichiometry: 23.0
species: 034363
type: SpeciesReference

149823
stoichiometry: 1.0
species: 032512
type: SpeciesReference

099295
stoichiometry: 1.0
species: 026747
type: SpeciesReference

040041
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Sodium_Na
type: Species

123794
stoichiometry: 1.0
species: 032609
type: SpeciesReference

031544
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Farnesyl diphosphate_C15H25O7P2
type: Species

118702
stoichiometry: 3.0
species: 024010
type: SpeciesReference

061850
stoichiometry: 1.0
species: 025142
type: SpeciesReference

039365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Mesaconyl-CoA_C26H35N7O19P3S
type: Species

052495
stoichiometry: 3.0
species: 027097
type: SpeciesReference

127777
stoichiometry: 12.0
species: 034253
type: SpeciesReference

064585
stoichiometry: 1.0
species: 042331
type: SpeciesReference

054257
stoichiometry: 2.0
species: 028376
type: SpeciesReference

137338
stoichiometry: 1.0
species: 040077
type: SpeciesReference

138711
stoichiometry: 1.0
species: 042283
type: SpeciesReference

034617
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Hexadecanoate (n-C16:0)_C16H31O2
type: Species

053966
stoichiometry: 1.0
species: 030783
type: SpeciesReference

148794
stoichiometry: 1.0
species: 024525
type: SpeciesReference

071451
stoichiometry: 1.0
species: 040029
type: SpeciesReference

024034
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: ADP_C10H12N5O10P2
type: Species

085650
stoichiometry: 1.0
species: 030989
type: SpeciesReference

110523
stoichiometry: 1.0
species: 037886
type: SpeciesReference

048043
stoichiometry: 1.0
species: 037729
type: SpeciesReference

134002
stoichiometry: 1.0
species: 026143
type: SpeciesReference

058216
stoichiometry: 1.0
species: 037693
type: SpeciesReference

027470
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: L-Carnitine_C7H15NO3
type: Species

073311
stoichiometry: 1.0
species: 022619
type: SpeciesReference

085878
stoichiometry: 1.0
species: 039128
type: SpeciesReference

121018
stoichiometry: 1.0
species: 028571
type: SpeciesReference

927593
is: ENSMMUG00000010257.2
product: 083495
fast: false
reactant: 083410
reactant: 083362
product: 083458
reversible: false
notes: R_BTNt3i subsystem: Transport, Extracellular R_BTNt3i equation: atp[c] + btn[e] + h2o[c] + (2) na1[e] --> adp[c] + btn[c] + h[c] + (2) na1[c] + pi[c] R_LIPOti subsystem: Transport, Extracellular R_LIPOti equation: atp[c] + h2o[c] + lipoate[e] + (2) na1[e] --> adp[c] + h[c] + lipoate[c] + (2) na1[c] + pi[c] R_PNTOt5 subsystem: Transport, Extracellular R_PNTOt5 equation: atp[c] + h2o[c] + (2) na1[e] + pnto-R[e] --> adp[c] + h[c] + (2) na1[c] + pi[c] + pnto-R[c]
reactant: 083386
reactant: 083398
product: 083483
product: 083446
product: 083422
reactant: 083350
product: 083471
type: Reaction
product: 083434
reactant: 083374

075362
stoichiometry: 1.0
species: 026941
type: SpeciesReference

142198
stoichiometry: 1.0
species: 019385
type: SpeciesReference

025649
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: beta-Aminopropion aldehyde_C3H8NO
type: Species

142307
stoichiometry: 18.0
species: 042331
type: SpeciesReference

028848
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: Deoxycytidine_C9H13N3O4
type: Species

065825
stoichiometry: 1.0
species: 024501
type: SpeciesReference

079370
stoichiometry: 8.0
species: 040029
type: SpeciesReference

929383
is: http://identifiers.org/ec-code/2.3.1.87
is: ENSMMUG00000018970.2
notes: R_SRTNACT subsystem: Tryptophan metabolism R_SRTNACT equation: [c] : accoa + srtn --> Nacsertn + coa + h R_CHSTEROLtg subsystem: Transport, Golgi Apparatus R_CHSTEROLtg equation: atp[c] + chsterol[g] + h2o[c] --> adp[c] + chsterol[c] + h[c] + pi[c] R_CHSTEROLt subsystem: Transport, Extracellular R_CHSTEROLt equation: atp[c] + chsterol[c] + h2o[c] --> adp[c] + chsterol[e] + h[c] + pi[c]
reactant: 101686
reversible: false
product: 101759
product: 101735
reactant: 101698
type: Reaction
product: 101795
reactant: 101710
fast: false
reactant: 101650
product: 101747
product: 101723
product: 101783
product: 101771
reactant: 101674
reactant: 101662

083915
stoichiometry: 1.0
species: 028267
type: SpeciesReference

030807
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: estradiol glucuronide_C24H32O8
type: Species

103633
stoichiometry: 1.0
species: 022510
type: SpeciesReference

143128
stoichiometry: 1.0
species: 037256
type: SpeciesReference

078609
stoichiometry: 1.0
species: 027735
type: SpeciesReference

031604
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: V3Fuc-nLc6Cer_C64H112N3O36FULLRCO
type: Species

048307
stoichiometry: 1.0
species: 024022
type: SpeciesReference

052267
stoichiometry: 1.0
species: 040174
type: SpeciesReference

118342
stoichiometry: 1.0
species: 020942
type: SpeciesReference

934000
product: 147707
product: 147683
is: ENSMMUG00000002196.1
fast: false
product: 147695
reactant: 147635
is: ENSMMUG00000002198.2
type: Reaction
reversible: false
reactant: 147647
product: 147671
notes: R_GPIDAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDAer equation: [r] : gpi_prot_hs + h2o --> dgpi_prot_hs + h + hdca R_GPIDA2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDA2er equation: [r] : em2emgacpail_prot_hs + h2o --> dem2emgacpail_prot_hs + h + hdca
reactant: 147659

075926
stoichiometry: 1.0
species: 029969
type: SpeciesReference

070490
stoichiometry: 1.0
species: 027145
type: SpeciesReference

058953
stoichiometry: 1.0
species: 031181
type: SpeciesReference

038044
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

116038
stoichiometry: 1.0
species: 029151
type: SpeciesReference

138266
stoichiometry: 1.0
species: 034363
type: SpeciesReference

075665
stoichiometry: 3.0
species: 027073
type: SpeciesReference

065297
stoichiometry: 1.0
species: 036944
type: SpeciesReference

063790
stoichiometry: 1.0
species: 029801
type: SpeciesReference

047513
stoichiometry: 1.0
species: 032584
type: SpeciesReference

134556
stoichiometry: 2.0
species: 046211
type: SpeciesReference

054687
stoichiometry: 1.0
species: 023078
type: SpeciesReference

063646
stoichiometry: 1.0
species: 032911
type: SpeciesReference

151895
stoichiometry: 3.0
species: 040138
type: SpeciesReference

145757
stoichiometry: 2.0
species: 036401
type: SpeciesReference

045815
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Oxidized thioredoxin_X
type: Species

100950
stoichiometry: 1.0
species: 038996
type: SpeciesReference

934336
reactant: 150282
product: 150306
product: 150318
name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
reversible: false
product: 150294
type: Reaction
fast: false
is: ENSMMUG00000031605.1
reactant: 150270
notes: R_B3GNT51g subsystem: Blood Group Biosynthesis R_B3GNT51g equation: [g] : galgluside_hs + uacgam --> acglcgalgluside_hs + h + udp

147780
stoichiometry: 4.0
species: 040017
type: SpeciesReference

145322
stoichiometry: 82.0
species: 034290
type: SpeciesReference

028279
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Hydrogen cyanide_CHN
type: Species

120345
stoichiometry: 1.0
species: 035049
type: SpeciesReference

041006
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S
type: Species

061310
stoichiometry: 1.0
species: 020131
type: SpeciesReference

060758
stoichiometry: 1.0
species: 030042
type: SpeciesReference

931801
reactant: 125266
product: 125290
notes: R_CYSGLYex subsystem: Transport, Extracellular R_CYSGLYex equation: cys-L[c] + gly[e] --> cys-L[e] + gly[c]
product: 125302
is: ENSMMUG00000019653.2
reactant: 125278
reversible: false
type: Reaction
name: L-cysteine/glycine exchanger
fast: false

071306
stoichiometry: 1.0
species: 040789
type: SpeciesReference

027894
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4_C31H47NO35S3
type: Species

090455
stoichiometry: 1.0
species: 041018
type: SpeciesReference

053303
stoichiometry: 1.0
species: 039595
type: SpeciesReference

082322
stoichiometry: 1.0
species: 030357
type: SpeciesReference

050516
stoichiometry: 32.0
species: 034448
type: SpeciesReference

092064
stoichiometry: 33.0
species: 027434
type: SpeciesReference

047887
stoichiometry: 1.0
species: 035896
type: SpeciesReference

073166
stoichiometry: 1.0
species: 038489
type: SpeciesReference

107690
stoichiometry: 5.0
species: 034387
type: SpeciesReference

114887
stoichiometry: 1.0
species: 036233
type: SpeciesReference

927041
product: 078477
notes: R_PNTK subsystem: CoA Biosynthesis R_PNTK equation: [c] : atp + pnto-R --> 4ppan + adp + h
name: pantothenate kinase
fast: false
type: Reaction
product: 078453
product: 078465
is: ENSMMUG00000014686.2
reactant: 078441
reversible: false
is: http://identifiers.org/ec-code/2.7.1.33
is: ENSMMUG00000012521.2
is: ENSMMUG00000010780.2
reactant: 078429

057299
stoichiometry: 1.0
species: 033894
type: SpeciesReference

085950
stoichiometry: 1.0
species: 040102
type: SpeciesReference

117968
stoichiometry: 1.0
species: 024034
type: SpeciesReference

115905
stoichiometry: 1.0
species: 030199
type: SpeciesReference

099524
stoichiometry: 1.0
species: 033445
type: SpeciesReference

924832
type: Reaction
fast: false
reactant: 058542
is: ENSMMUG00000001593.2
reversible: false
name: Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)
product: 058554
notes: R_HGNTOR subsystem: Tyrosine metabolism R_HGNTOR equation: [c] : hgentis + o2 --> 4mlacac + h
is: http://identifiers.org/ec-code/1.13.11.5
product: 058566
reactant: 058530

105499
stoichiometry: 5.0
species: 033034
type: SpeciesReference

930312
product: 109742
fast: false
product: 109706
modifier: 109839
reactant: 109574
modifier: 109827
product: 109634
modifier: 109851
reactant: 109453
modifier: 109975
modifier: 109949
reactant: 109441
notes: R_VLCSp subsystem: Bile Acid Biosynthesis R_VLCSp equation: [x] : atp + coa + thcholstoic --> amp + cholcoar + ppi R_VLCS2p subsystem: Bile Acid Biosynthesis R_VLCS2p equation: [x] : atp + coa + dhcholestanate --> amp + dhcholestancoa + ppi R_FATP9t subsystem: Transport, Extracellular R_FATP9t equation: na1[c] + nrvnc[c] <==> na1[e] + nrvnc[e] R_FATP7t subsystem: Transport, Extracellular R_FATP7t equation: crvnc[c] + na1[c] <==> crvnc[e] + na1[e] R_FACOAL191 subsystem: Fatty acid activation R_FACOAL191 equation: [c] : atp + coa + prist --> amp + ppi + pristcoa R_FACOAL206 subsystem: Fatty acid activation R_FACOAL206 equation: [c] : atp + coa + phyt <==> amp + phytcoa + ppi R_VLCSr subsystem: Bile Acid Biosynthesis R_VLCSr equation: [r] : atp + coa + thcholstoic --> amp + cholcoar + ppi R_CYTDt4 subsystem: Transport, Extracellular R_CYTDt4 equation: cytd[e] + na1[e] --> cytd[c] + na1[c] R_FATP6t subsystem: Transport, Extracellular R_FATP6t equation: adrn[c] + na1[c] <==> adrn[e] + na1[e] R_FATP8t subsystem: Transport, Extracellular R_FATP8t equation: lgnc[c] + na1[c] <==> lgnc[e] + na1[e] R_ADNt4 subsystem: Transport, Extracellular R_ADNt4 equation: adn[e] + na1[e] --> adn[c] + na1[c] R_URIt4 subsystem: Transport, Extracellular R_URIt4 equation: na1[e] + uri[e] --> na1[c] + uri[c] R_THMDt4 subsystem: Transport, Extracellular R_THMDt4 equation: na1[e] + thymd[e] --> na1[c] + thymd[c] R_VLCS2r subsystem: Bile Acid Biosynthesis R_VLCS2r equation: [r] : atp + coa + dhcholestanate --> amp + dhcholestancoa + ppi
product: 109803
modifier: 109875
modifier: 109936
modifier: 109863
reactant: 109598
product: 109718
reactant: 109586
product: 109682
reactant: 109477
reactant: 109489
product: 109622
reactant: 109465
modifier: 109962
reversible: false
is: http://identifiers.org/ec-code/6.2.1.7
product: 109766
product: 109791
reactant: 109550
type: Reaction
product: 109646
reactant: 109538
modifier: 109912
product: 109779
reactant: 109514
product: 109694
reactant: 109501
reactant: 109610
product: 109754
is: http://identifiers.org/ec-code/6.2.1.3
product: 109670
modifier: 109899
is: ENSMMUG00000016772.2
reactant: 109562
modifier: 109988
modifier: 109887
modifier: 109924
product: 109730
modifier: 110001
reactant: 109526
product: 109658
modifier: 109815
reactant: 109429

139653
stoichiometry: 2.0
species: 031423
type: SpeciesReference

057588
stoichiometry: 1.0
species: 030030
type: SpeciesReference

126520
stoichiometry: 1.0
species: 044077
type: SpeciesReference

132208
stoichiometry: 2.0
species: 038622
type: SpeciesReference

028110
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 4_C45H65N2O48S4X
type: Species

085325
stoichiometry: 1.0
species: 027398
type: SpeciesReference

024365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: S-Adenosyl-L-homocysteine_C14H20N6O5S
type: Species

055039
stoichiometry: 1.0
species: 024190
type: SpeciesReference

042355
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Phosphate_HO4P
type: Species

083603
stoichiometry: 2.0
species: 034436
type: SpeciesReference

049286
stoichiometry: 1.0
species: 046223
type: SpeciesReference

068585
stoichiometry: 1.0
species: 019409
type: SpeciesReference

069707
stoichiometry: 1.0
species: 043368
type: SpeciesReference

102386
stoichiometry: 1.0
species: 025433
type: SpeciesReference

064308
stoichiometry: 1.0
species: 023719
type: SpeciesReference

066570
stoichiometry: 2.0
species: 024010
type: SpeciesReference

111837
stoichiometry: 1.0
species: 045357
type: SpeciesReference

032184
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
type: Species

055742
stoichiometry: 1.0
species: 025541
type: SpeciesReference

076084
stoichiometry: 1.0
species: 044379
type: SpeciesReference

069671
stoichiometry: 1.0
species: 023514
type: SpeciesReference

103548
stoichiometry: 2.0
species: 040077
type: SpeciesReference

033676
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: GMP_C10H12N5O8P
type: Species

137121
stoichiometry: 2.0
species: 042524
type: SpeciesReference

146299
stoichiometry: 2.0
species: 040198
type: SpeciesReference

028412
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Cytidine_C9H13N3O5
type: Species

044546
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Serotonin_C10H13N2O
type: Species

927713
type: Reaction
notes: R_PTPAT subsystem: CoA Biosynthesis R_PTPAT equation: [c] : atp + h + pan4p <==> dpcoa + ppi R_DPCOAK subsystem: CoA Biosynthesis R_DPCOAK equation: [c] : atp + dpcoa --> adp + coa + h
modifier: 085288
modifier: 085276
product: 085216
is: ENSMMUG00000009886.2
product: 085204
is: http://identifiers.org/ec-code/2.7.1.24
modifier: 085264
modifier: 085252
fast: false
reactant: 085179
is: http://identifiers.org/ec-code/2.7.7.3
modifier: 085240
reactant: 085191
product: 085228
reversible: false

131943
stoichiometry: 1.0
species: 032306
type: SpeciesReference

113272
stoichiometry: 1.0
species: 037717
type: SpeciesReference

091535
stoichiometry: 3.0
species: 031133
type: SpeciesReference

033311
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Glycine_C2H5NO2
type: Species

036017
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Inosine_C10H12N4O5
type: Species

ORG:
  orgname: University of Missouri - Columbia
n:
  given: Michael
  family: Bekaert

120453
stoichiometry: 1.0
species: 039619
type: SpeciesReference

145054
stoichiometry: 1.0
species: 027674
type: SpeciesReference

029643
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dITP_C10H11N4O13P3
type: Species

032911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Glucose_C6H12O6
type: Species

109321
stoichiometry: 1.0
species: 031013
type: SpeciesReference

147059
stoichiometry: 2.0
species: 040077
type: SpeciesReference

109105
stoichiometry: 1.0
species: 033119
type: SpeciesReference

931063
fast: false
product: 118173
is: http://identifiers.org/ec-code/2.7.7.18
is: ENSMMUG00000017549.2
is: http://identifiers.org/ec-code/3.6.1.9
product: 118185
reactant: 118137
product: 118161
reactant: 118100
is: ENSMMUG00000004903.2
product: 118221
reactant: 118149
product: 118197
reactant: 118112
product: 118233
reactant: 118125
reactant: 118088
product: 118209
reversible: false
notes: R_UDPGP subsystem: Starch and Sucrose Metabolism R_UDPGP equation: [c] : h2o + udpg --> g1p + (2) h + ump R_NNAT subsystem: NAD Metabolism R_NNAT equation: [c] : atp + h + nicrnt --> dnad + ppi R_DNADDP subsystem: NAD Metabolism R_DNADDP equation: [c] : dnad + h2o --> amp + (2) h + nicrnt
type: Reaction

079154
stoichiometry: 1.0
species: 024365
type: SpeciesReference

135301
stoichiometry: 1.0
species: 040246
type: SpeciesReference

023635
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Acetylcholine_C7H16NO2
type: Species

926609
reversible: false
reactant: 074975
is: ENSMMUG00000002461.2
product: 075011
reactant: 074963
fast: false
reactant: 074987
product: 075035
product: 075023
type: Reaction
notes: R_CEPTE subsystem: Glycerophospholipid Metabolism R_CEPTE equation: [c] : cdpea + dag_hs --> cmp + h + pe_hs R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs
product: 074999

090973
stoichiometry: 1.0
species: 027097
type: SpeciesReference

046599
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Urate_C5H4N4O3
type: Species

024586
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: beta-Alanine_C3H7NO2
type: Species

072622
stoichiometry: 1.0
species: 032717
type: SpeciesReference

076484
stoichiometry: 1.0
species: 046500
type: SpeciesReference

038730
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

089850
stoichiometry: 1.0
species: 039475
type: SpeciesReference

086579
stoichiometry: 2.0
species: 038754
type: SpeciesReference

933952
is: ENSMMUG00000012240.2
reactant: 147263
product: 147347
product: 147323
is: ENSMMUG00000007161.2
reactant: 147287
reactant: 147275
notes: R_M4BTAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4BTAer equation: [r] : mem2emgacpail_hs + pre_prot --> gpi_sig + mem2emgacpail_prot_hs R_H8TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8TAer equation: [r] : gpi_hs + pre_prot --> gpi_prot_hs + gpi_sig R_M4ATAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4ATAer equation: [r] : m(em)3gacpail_hs + pre_prot --> gpi_sig + m(em)3gacpail_prot_hs R_H7_APOS_TAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7_APOS_TAer equation: [r] : em2emgacpail_hs + pre_prot --> em2emgacpail_prot_hs + gpi_sig
product: 147311
reactant: 147299
is: ENSMMUG00000020217.2
product: 147335
type: Reaction
product: 147359
fast: false
reactant: 147251
reversible: false
is: ENSMMUG00000017682.2

036715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 9_C188H301N13O166S10
type: Species

030333
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: dTTP_C10H13N2O14P3
type: Species

025963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Butyrate (n-C4:0)_C4H7O2
type: Species

149506
stoichiometry: 1.0
species: 025879
type: SpeciesReference

070080
stoichiometry: 1.0
species: 033046
type: SpeciesReference

035073
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Hydroxypyruvate_C3H3O4
type: Species

098164
stoichiometry: 1.0
species: 041982
type: SpeciesReference

109742
stoichiometry: 1.0
species: 029283
type: SpeciesReference

091752
stoichiometry: 1.0
species: 028497
type: SpeciesReference

927269
product: 080204
product: 080192
notes: R_RDH3 subsystem: Vitamin A Metabolism R_RDH3 equation: [c] : nad + retinol-cis-11 <==> h + nadh + retinal-11-cis R_RDH2 subsystem: Vitamin A Metabolism R_RDH2 equation: [c] : nad + retinol-9-cis <==> h + nadh + retinal-cis-9 R_RDH1 subsystem: Vitamin A Metabolism R_RDH1 equation: [c] : nad + retinol <==> h + nadh + retinal R_RDH4 subsystem: Vitamin A Metabolism R_RDH4 equation: [c] : nad + retinol-cis-13 <==> h + nadh + retinal-cis-13
is: ENSMMUG00000013228.2
product: 080252
product: 080240
reactant: 080132
reversible: true
product: 080228
reactant: 080180
reactant: 080156
is: http://identifiers.org/ec-code/1.1.1.105
reactant: 080144
reactant: 080168
fast: false
type: Reaction
product: 080216

134375
stoichiometry: 1.0
species: 026131
type: SpeciesReference

112694
stoichiometry: 1.0
species: 020750
type: SpeciesReference

029945
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10
type: Species

113055
stoichiometry: 11.0
species: 046211
type: SpeciesReference

082769
stoichiometry: 3.0
species: 040029
type: SpeciesReference

091607
stoichiometry: 1.0
species: 039703
type: SpeciesReference

141584
stoichiometry: 1.0
species: 040390
type: SpeciesReference

087848
stoichiometry: 1.0
species: 026530
type: SpeciesReference

130576
stoichiometry: 1.0
species: 030418
type: SpeciesReference

115152
stoichiometry: 1.0
species: 036497
type: SpeciesReference

039032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Malonyl-CoA_C24H33N7O19P3S
type: Species

062982
stoichiometry: 1.0
species: 028146
type: SpeciesReference

140956
stoichiometry: 1.0
species: 020009
type: SpeciesReference

077389
stoichiometry: 1.0
species: 035762
type: SpeciesReference

144365
stoichiometry: 1.0
species: 025215
type: SpeciesReference

117764
stoichiometry: 1.0
species: 041681
type: SpeciesReference

121836
stoichiometry: 1.0
species: 040174
type: SpeciesReference

034833
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: hexacosanoyl carnitine_C33H65NO4
type: Species

020191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3,4-Dihydroxymandelate_C8H7O5
type: Species

125399
stoichiometry: 2.0
species: 034363
type: SpeciesReference

081187
stoichiometry: 1.0
species: 024010
type: SpeciesReference

127488
stoichiometry: 1.5
species: 040849
type: SpeciesReference

042692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Inorganic triphosphate_HO10P3
type: Species

034192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Hydrogen peroxide_H2O2
type: Species

096225
stoichiometry: 1.0
species: 027073
type: SpeciesReference

136699
stoichiometry: 1.0
species: 041018
type: SpeciesReference

079045
stoichiometry: 1.0
species: 025505
type: SpeciesReference

052279
stoichiometry: 2.0
species: 030551
type: SpeciesReference

110740
stoichiometry: 2.0
species: 034253
type: SpeciesReference

928110
product: 088245
product: 088185
reversible: false
product: 088233
reactant: 088149
type: Reaction
product: 088197
is: http://identifiers.org/ec-code/1.1.1.34
product: 088221
reactant: 088161
notes: R_HMGCOARr subsystem: Cholesterol Metabolism R_HMGCOARr equation: [r] : (2) h + hmgcoa + (2) nadph --> coa + mev-R + (2) nadp R_HMGCOARx subsystem: Cholesterol Metabolism R_HMGCOARx equation: [x] : (2) h + hmgcoa + (2) nadph --> coa + mev-R + (2) nadp
fast: false
reactant: 088125
reactant: 088137
is: ENSMMUG00000006139.2
product: 088209
reactant: 088112
reactant: 088173

121235
stoichiometry: 1.0
species: 029921
type: SpeciesReference

135721
stoichiometry: 1.0
species: 019549
type: SpeciesReference

028993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
type: Species

056406
stoichiometry: 2.0
species: 022388
type: SpeciesReference

926489
type: Reaction
reversible: false
fast: false
product: 074014
product: 074002
is: ENSMMUG00000007828.2
notes: R_MTHFR3 subsystem: Folate Metabolism R_MTHFR3 equation: [c] : (2) h + mlthf + nadph --> 5mthf + nadp
reactant: 073978
name: _5,10-methylenetetrahydrofolatereductase (NADPH)
reactant: 073990
reactant: 073966
is: http://identifiers.org/ec-code/1.5.1.20

071873
stoichiometry: 1.0
species: 041259
type: SpeciesReference

142982
stoichiometry: 3.0
species: 040789
type: SpeciesReference

078765
stoichiometry: 1.0
species: 038489
type: SpeciesReference

119572
stoichiometry: 1.0
species: 045105
type: SpeciesReference

137664
stoichiometry: 1.0
species: 040222
type: SpeciesReference

925096
notes: R_ADSELK subsystem: Selenoamino acid metabolism R_ADSELK equation: [c] : adsel + atp --> 3padsel + adp + h R_SELADT subsystem: Selenoamino acid metabolism R_SELADT equation: [c] : atp + h + sel --> adsel + ppi R_SADT subsystem: Nucleotides R_SADT equation: [c] : atp + h + so4 --> aps + ppi R_ADSK subsystem: Nucleotides R_ADSK equation: [c] : aps + atp --> adp + h + paps
product: 061910
reactant: 061778
is: http://identifiers.org/ec-code/2.7.1.25
product: 061886
product: 061862
reactant: 061814
reactant: 061802
reversible: false
fast: false
is: ENSMMUG00000019907.2
product: 061850
reactant: 061838
type: Reaction
product: 061922
reactant: 061790
reactant: 061826
product: 061898
product: 061874
is: ENSMMUG00000006411.2
is: http://identifiers.org/ec-code/2.7.7.4

054699
stoichiometry: 1.0
species: 034375
type: SpeciesReference

043620
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: cis-13-retinal_C20H28O
type: Species

141908
stoichiometry: 1.0
species: 025541
type: SpeciesReference

931489
reversible: false
product: 122617
is: http://identifiers.org/ec-code/3.1.4.11
reactant: 122485
product: 122593
reactant: 122533
reactant: 122497
product: 122629
notes: R_PI4PLC subsystem: Inositol Phosphate Metabolism R_PI4PLC equation: [c] : h2o + pail4p_hs --> dag_hs + h + mi14p R_PI45PLC subsystem: Inositol Phosphate Metabolism R_PI45PLC equation: [c] : h2o + pail45p_hs --> dag_hs + h + mi145p R_PIPLC subsystem: Inositol Phosphate Metabolism R_PIPLC equation: [c] : h2o + pail_hs --> dag_hs + h + mi1p-D R_PI45PLCn subsystem: Inositol Phosphate Metabolism R_PI45PLCn equation: [n] : h2o + pail45p_hs --> dag_hs + h + mi145p R_PIPLCn subsystem: Inositol Phosphate Metabolism R_PIPLCn equation: [n] : h2o + pail_hs --> dag_hs + h + mi1p-D R_PI4PLCn subsystem: Inositol Phosphate Metabolism R_PI4PLCn equation: [n] : h2o + pail4p_hs --> dag_hs + h + mi14p
product: 122641
reactant: 122509
product: 122545
fast: false
product: 122569
reactant: 122473
product: 122653
product: 122557
is: ENSMMUG00000004313.2
product: 122605
reactant: 122449
type: Reaction
reactant: 122521
reactant: 122461
product: 122581
is: http://identifiers.org/ec-code/3.1.4.3

039559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: _1D-myo-Inositol 1,4,5,6-tetrakisphosphate_C6H8O18P4
type: Species

074435
stoichiometry: 1.0
species: 026832
type: SpeciesReference

021823
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Hydroxy-L-tryptophan_C11H12N2O3
type: Species

047959
stoichiometry: 1.0
species: 021787
type: SpeciesReference

928302
reactant: 090600
product: 090853
reactant: 090359
reactant: 090563
reactant: 090322
reactant: 090551
product: 090768
product: 090780
product: 090708
reactant: 090479
product: 090720
reactant: 090419
notes: R_FAOXC183806m subsystem: Fatty acid oxidation R_FAOXC183806m equation: [m] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC161802m subsystem: Fatty acid activation R_FAOXC161802m equation: [m] : (4) coa + (3) fad + (4) h2o + hdd2coa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC160 subsystem: Fatty acid oxidation R_FAOXC160 equation: [m] : (7) coa + (7) fad + (7) h2o + (7) nad + pmtcoa --> (8) accoa + (7) fadh2 + (7) h + (7) nadh R_FAOXC2031836m subsystem: Fatty acid oxidation R_FAOXC2031836m equation: [m] : coa + dlnlcgcoa + fad + h2o + nad --> accoa + fadh2 + h + lnlncgcoa + nadh R_FAOXC80 subsystem: Fatty acid oxidation R_FAOXC80 equation: [m] : (3) coa + (3) fad + (3) h2o + (3) nad + occoa --> (4) accoa + (3) fadh2 + (3) h + (3) nadh R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_FAOXC2251836m subsystem: Fatty acid oxidation R_FAOXC2251836m equation: [m] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC18280m subsystem: Fatty acid oxidation R_FAOXC18280m equation: [m] : (5) coa + (3) fad + (5) h2o + lneldccoa + (5) nad --> (5) accoa + (3) fadh2 + (5) h + (5) nadh + occoa R_FAOXC16180m subsystem: Fatty acid oxidation R_FAOXC16180m equation: [m] : (4) coa + (3) fad + (4) h2o + hdcoa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC2051843m subsystem: Fatty acid oxidation R_FAOXC2051843m equation: [m] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC183803m subsystem: Fatty acid oxidation R_FAOXC183803m equation: [m] : (5) coa + (2) fad + (5) h2o + lnlncacoa + (5) nad --> (5) accoa + (2) fadh2 + (5) h + (5) nadh + occoa R_FAOXC2242046m subsystem: Fatty acid oxidation R_FAOXC2242046m equation: [m] : adrncoa + coa + fad + h2o + nad --> accoa + arachdcoa + fadh2 + h + nadh R_FAOXC200180m subsystem: Fatty acid oxidation R_FAOXC200180m equatio…
reactant: 090467
reactant: 090407
product: 090816
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 090371
is: ENSMMUG00000020648.2
product: 090744
reactant: 090527
fast: false
reactant: 090455
reactant: 090515
reactant: 090443
reactant: 090672
product: 090684
reactant: 090660
product: 090828
product: 090792
product: 090840
reactant: 090588
reactant: 090648
reactant: 090395
reactant: 090503
reactant: 090431
reactant: 090383
reactant: 090539
product: 090756
reactant: 090636
reactant: 090624
reactant: 090491
product: 090696
is: http://identifiers.org/ec-code/1.3.99.3
product: 090804
reversible: false
reactant: 090346
type: Reaction
reactant: 090575
reactant: 090334
product: 090732
reactant: 090612

100396
stoichiometry: 2.0
species: 034363
type: SpeciesReference

053748
stoichiometry: 1.0
species: 030941
type: SpeciesReference

086036
stoichiometry: 1.0
species: 034929
type: SpeciesReference

114527
stoichiometry: 1.0
species: 020545
type: SpeciesReference

034076
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: GTP_C10H12N5O14P3
type: Species

142524
stoichiometry: 1.0
species: 040306
type: SpeciesReference

077449
stoichiometry: 1.0
species: 035969
type: SpeciesReference

107124
stoichiometry: 2.0
species: 020179
type: SpeciesReference

058434
stoichiometry: 1.0
species: 040198
type: SpeciesReference

149602
stoichiometry: 1.0
species: 042560
type: SpeciesReference

928638
type: Reaction
fast: false
reactant: 094814
product: 094838
reversible: false
is: ENSMMUG00000004142.1
is: http://identifiers.org/ec-code/3.6.1.28
reactant: 094826
name: thiamine-triphosphatase
notes: R_THMTP subsystem: Thiamine Metabolism R_THMTP equation: [c] : h2o + thmtp --> h + pi + thmpp
product: 094862
product: 094850

148867
stoichiometry: 1.0
species: 029066
type: SpeciesReference

078826
stoichiometry: 1.0
species: 038501
type: SpeciesReference

093883
stoichiometry: 1.0
species: 040402
type: SpeciesReference

043356
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Pantetheine_C11H22N2O4S
type: Species

088486
stoichiometry: 1.0
species: 024300
type: SpeciesReference

105668
stoichiometry: 5.0
species: 044174
type: SpeciesReference

063935
stoichiometry: 1.0
species: 041910
type: SpeciesReference

084795
stoichiometry: 1.0
species: 038068
type: SpeciesReference

066029
stoichiometry: 7.0
species: 040390
type: SpeciesReference

067837
stoichiometry: 1.0
species: 030916
type: SpeciesReference

082104
stoichiometry: 1.0
species: 034253
type: SpeciesReference

046163
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Tyrosine_C9H11NO3
type: Species

144668
stoichiometry: 35.0
species: 040186
type: SpeciesReference

081767
stoichiometry: 2.0
species: 029320
type: SpeciesReference

923812
fast: false
notes: R_HSD17B7r subsystem: Steroid Metabolism R_HSD17B7r equation: [r] : estrone + h + nadph --> estradiol + nadp R_HSD17B9r subsystem: Steroid Metabolism R_HSD17B9r equation: [r] : andrstrn + h + nadph + (1.5) o2 --> eandrstrn + (2) h2o + nadp
product: 049707
reversible: false
is: http://identifiers.org/ec-code/1.1.1.62
reactant: 049634
reactant: 049659
is: ENSMMUG00000009332.2
type: Reaction
reactant: 049610
product: 049695
product: 049683
reactant: 049647
reactant: 049622
product: 049671

116897
stoichiometry: 1.0
species: 040402
type: SpeciesReference

051612
stoichiometry: 3.0
species: 040029
type: SpeciesReference

929167
product: 099899
product: 099911
notes: R_ASNNm subsystem: Alanine and Aspartate Metabolism R_ASNNm equation: [m] : asn-L + h2o --> asp-L + nh4
reactant: 099875
type: Reaction
is: ENSMMUG00000013831.2
reactant: 099887
name: L-asparaginase (mitochondrial)
reversible: false
fast: false
is: http://identifiers.org/ec-code/3.5.1.1

108354
stoichiometry: 1.0
species: 039365
type: SpeciesReference

092282
stoichiometry: 1.0
species: 038393
type: SpeciesReference

129092
stoichiometry: 1.0
species: 038803
type: SpeciesReference

083061
stoichiometry: 1.0
species: 043452
type: SpeciesReference

036582
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 37_C62H104N4O46
type: Species

150714
stoichiometry: 3.0
species: 044162
type: SpeciesReference

020313
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: _3',5'-Cyclic GMP_C10H11N5O7P
type: Species

022388
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Dopachrome_C9H6NO4
type: Species

023755
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: N-Acetylneuraminate_C11H18NO9
type: Species

095824
stoichiometry: 1.0
species: 026083
type: SpeciesReference

148105
stoichiometry: 1.0
species: 044947
type: SpeciesReference

136289
stoichiometry: 1.0
species: 043981
type: SpeciesReference

125013
stoichiometry: 1.0
species: 042584
type: SpeciesReference

044863
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2
type: Species

042800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: pregnenolone sulfate_C21H31O5S
type: Species

054966
stoichiometry: 1.0
species: 044657
type: SpeciesReference

125918
stoichiometry: 2.0
species: 040897
type: SpeciesReference

090672
stoichiometry: 3.0
species: 040813
type: SpeciesReference

932570
is: http://identifiers.org/ec-code/1.1.1.31
is: ENSMMUG00000023134.2
product: 133100
reactant: 133052
reactant: 133064
reversible: true
product: 133076
fast: false
type: Reaction
product: 133088
notes: R_HIBDm subsystem: Valine, Leucine, and Isoleucine Metabolism R_HIBDm equation: [m] : 3hmp + nad <==> 2mop + h + nadh
name: _3-hydroxyisobutyrate dehydrogenase, mitochondrial

049985
stoichiometry: 1.0
species: 027747
type: SpeciesReference

037633
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 9_C83H133N7O64S2X
type: Species

095102
stoichiometry: 1.0
species: 030381
type: SpeciesReference

109598
stoichiometry: 1.0
species: 023962
type: SpeciesReference

037390
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 5_C61H99N5O43X
type: Species

061142
stoichiometry: 1.0
species: 045008
type: SpeciesReference

093546
stoichiometry: 1.0
species: 033505
type: SpeciesReference

116256
stoichiometry: 12.0
species: 040789
type: SpeciesReference

071523
stoichiometry: 2.0
species: 040029
type: SpeciesReference

146805
stoichiometry: 1.0
species: 030381
type: SpeciesReference

934192
notes: R_LPASE subsystem: Glycerophospholipid Metabolism R_LPASE equation: [c] : h2o + lpchol_hs --> Rtotal + g3pc + h
product: 149422
reactant: 149386
product: 149410
is: ENSMMUG00000004245.2
is: ENSMMUG00000003527.2
reactant: 149374
is: ENSMMUG00000009527.2
product: 149398
name: lysophospholipase
type: Reaction
is: ENSMMUG00000021423.2
reversible: false
fast: false

060686
stoichiometry: 1.0
species: 039140
type: SpeciesReference

119717
stoichiometry: 1.0
species: 038296
type: SpeciesReference

055488
stoichiometry: 1.0
species: 030965
type: SpeciesReference

078972
stoichiometry: 1.0
species: 022704
type: SpeciesReference

094802
stoichiometry: 2.0
species: 031109
type: SpeciesReference

065079
stoichiometry: 1.0
species: 034857
type: SpeciesReference

107546
stoichiometry: 1.0
species: 020978
type: SpeciesReference

930532
is: ENSMMUG00000020132.2
product: 112066
product: 112078
reactant: 112029
product: 112103
is: http://identifiers.org/ec-code/2.4.1.148
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.102
reactant: 112041
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE4GTg subsystem: O-Glycan Biosynthesis R_CORE4GTg equation: [g] : core3 + uacgam --> core4 + h + udp
reversible: false
product: 112090
is: ENSMMUG00000018426.2
reactant: 112053
fast: false

045971
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: testosterone glucuronide_C25H36O8
type: Species

132353
stoichiometry: 2.0
species: 034436
type: SpeciesReference

068368
stoichiometry: 1.0
species: 022159
type: SpeciesReference

046379
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: UDPgalactose_C15H22N2O17P2
type: Species

027674
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 1_C45H67N2O46S3
type: Species

052158
stoichiometry: 1.0
species: 022316
type: SpeciesReference

041561
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: phosphatidylinositol-3,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2
type: Species

111498
stoichiometry: 1.0
species: 031834
type: SpeciesReference

929903
product: 105559
product: 105535
type: Reaction
reactant: 105403
reactant: 105451
is: ENSMMUG00000022163.2
product: 105620
product: 105632
reactant: 105439
product: 105596
reactant: 105523
product: 105668
reactant: 105391
product: 105547
product: 105571
fast: false
reactant: 105487
product: 105680
product: 105608
reactant: 105499
reversible: false
reactant: 105511
product: 105644
reactant: 105463
reactant: 105427
reactant: 105415
product: 105583
reactant: 105379
reactant: 105475
notes: R_ALAASNNaEx subsystem: Transport, Extracellular R_ALAASNNaEx equation: ala-L[e] + asn-L[c] + na1[e] --> ala-L[c] + asn-L[e] + na1[c] R_SERASNNaEx subsystem: Transport, Extracellular R_SERASNNaEx equation: asn-L[c] + na1[e] + ser-L[e] --> asn-L[e] + na1[c] + ser-L[c] R_GLNSERNaEx subsystem: Transport, Extracellular R_GLNSERNaEx equation: gln-L[e] + na1[e] + ser-L[c] --> gln-L[c] + na1[c] + ser-L[e] R_SERGLNNaEx subsystem: Transport, Extracellular R_SERGLNNaEx equation: gln-L[c] + na1[e] + ser-L[e] --> gln-L[e] + na1[c] + ser-L[c] R_CYSTHRNaEx subsystem: Transport, Extracellular R_CYSTHRNaEx equation: cys-L[e] + na1[e] + thr-L[c] --> cys-L[c] + na1[c] + thr-L[e] R_ASNGLNNaEx subsystem: Transport, Extracellular R_ASNGLNNaEx equation: asn-L[e] + gln-L[c] + na1[e] --> asn-L[c] + gln-L[e] + na1[c] R_GLNTHRNaEx subsystem: Transport, Extracellular R_GLNTHRNaEx equation: gln-L[e] + na1[e] + thr-L[c] --> gln-L[c] + na1[c] + thr-L[e] R_ASNTHRNaEx subsystem: Transport, Extracellular R_ASNTHRNaEx equation: asn-L[e] + na1[e] + thr-L[c] --> asn-L[c] + na1[c] + thr-L[e] R_THRSERNaEx subsystem: Transport, Extracellular R_THRSERNaEx equation: na1[e] + ser-L[c] + thr-L[e] --> na1[c] + ser-L[e] + thr-L[c] R_ALACYSNaEx subsystem: Transport, Extracellular R_ALACYSNaEx equation: ala-L[e] + cys-L[c] + na1[e] --> ala-L[c] + cys-L[e] + na1[c] R_GLNCYSNaEx subsystem: Transport, Extracellular R_GLNCYSNaEx equation: cys-L[c] + gln-L[e] + na1[e] --> cys-L[e] + gln-L[c] + na1[c] R_THRALANaEx subsystem: Transport, Extracellular R_THRALANaEx equation: ala-L[c] + na1[e] + thr-L[e] --> ala-L[e] + na1[c] + thr-L[c] R_GLNASNNaEx subsystem: Transport, Extracellular R_GLNASNNaEx equation: asn-L[c] + gln-L[e] + na1[e] --> asn-L[e] + gln-L[c] + na1[c] R_CYSALANaEx subsystem: Transport, Extracellular R_CYSALANaEx equation: ala-L[c] + cys-L[e] + na1[e] --> ala-L[e] + cys-L[c] + na1[c] R_CYSGLNNaEx subsystem: Transport, Extracellular R_CYSGLNNaEx equation: cys-L[e] + gln-L[c] + na1[e] --> cys-L[c] + gln-L[e]…
product: 105656

130007
stoichiometry: 1.0
species: 032923
type: SpeciesReference

927149
product: 079106
type: Reaction
notes: R_ASNS1 subsystem: Alanine and Aspartate Metabolism R_ASNS1 equation: [c] : asp-L + atp + gln-L + h2o --> amp + asn-L + glu-L + h + ppi
name: asparagine synthase (glutamine-hydrolysing)
reactant: 079045
product: 079093
fast: false
product: 079069
is: http://identifiers.org/ec-code/6.3.5.4
is: ENSMMUG00000019157.1
product: 079081
reactant: 079020
reactant: 079057
reversible: false
product: 079118
reactant: 079033

088342
stoichiometry: 1.0
species: 034253
type: SpeciesReference

134988
stoichiometry: 1.0
species: 045645
type: SpeciesReference

021135
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _4-(2-Aminophenyl)-2,4-dioxobutanoate_C10H8NO4
type: Species

063078
stoichiometry: 1.0
species: 027978
type: SpeciesReference

111619
stoichiometry: 1.0
species: 032343
type: SpeciesReference

131122
stoichiometry: 1.0
species: 046295
type: SpeciesReference

152186
stoichiometry: 1.0
species: 034363
type: SpeciesReference

056890
stoichiometry: 3.0
species: 034265
type: SpeciesReference

033894
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GT1a (homo sapiens)_C77H127N5O46FULLRCO
type: Species

118016
stoichiometry: 1.0
species: 034412
type: SpeciesReference

069526
stoichiometry: 1.0
species: 027882
type: SpeciesReference

086725
stoichiometry: 15.0
species: 039176
type: SpeciesReference

138110
stoichiometry: 1.0
species: 023659
type: SpeciesReference

122965
stoichiometry: 1.0
species: 025384
type: SpeciesReference

023066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Acetate_C2H3O2
type: Species

126773
stoichiometry: 1.0
species: 033966
type: SpeciesReference

041417
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2
type: Species

092390
stoichiometry: 1.0
species: 025324
type: SpeciesReference

031327
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide_C8H13N2O9P
type: Species

112272
stoichiometry: 1.0
species: 042331
type: SpeciesReference

098632
stoichiometry: 1.0
species: 035049
type: SpeciesReference

067945
stoichiometry: 1.0
species: 046367
type: SpeciesReference

051336
stoichiometry: 1.0
species: 037536
type: SpeciesReference

112115
stoichiometry: 1.0
species: 025541
type: SpeciesReference

079902
stoichiometry: 3.0
species: 040306
type: SpeciesReference

051492
stoichiometry: 1.0
species: 023235
type: SpeciesReference

103329
stoichiometry: 1.0
species: 023950
type: SpeciesReference

123121
stoichiometry: 1.0
species: 047045
type: SpeciesReference

106452
stoichiometry: 5.0
species: 040077
type: SpeciesReference

050661
stoichiometry: 1.0
species: 031980
type: SpeciesReference

116450
stoichiometry: 1.0
species: 030273
type: SpeciesReference

072902
stoichiometry: 2.0
species: 029849
type: SpeciesReference

140098
stoichiometry: 23.0
species: 046391
type: SpeciesReference

026929
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: clupanodonyl carnitine_C29H47NO4
type: Species

085505
stoichiometry: 3.0
species: 034436
type: SpeciesReference

053411
stoichiometry: 1.0
species: 033396
type: SpeciesReference

084229
stoichiometry: 1.0
species: 036161
type: SpeciesReference

024792
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: S-Adenosyl-L-methionine_C15H23N6O5S
type: Species

144510
stoichiometry: 2.0
species: 034448
type: SpeciesReference

097479
stoichiometry: 1.0
species: 040837
type: SpeciesReference

068911
stoichiometry: 1.0
species: 038634
type: SpeciesReference

925660
product: 067244
notes: R_B_MANNASEly subsystem: N-Glycan Degradation R_B_MANNASEly equation: [l] : h2o + mn --> acgam + man
product: 067256
is: ENSMMUG00000003739.2
reversible: false
reactant: 067232
name: beta-mannosidase, lysosomal
is: http://identifiers.org/ec-code/3.2.1.25
type: Reaction
fast: false
reactant: 067220

100506
stoichiometry: 1.0
species: 042524
type: SpeciesReference

136398
stoichiometry: 4.0
species: 034327
type: SpeciesReference

104933
stoichiometry: 1.0
species: 032306
type: SpeciesReference

934084
fast: false
reactant: 148481
reactant: 148517
product: 148589
reactant: 148541
product: 148637
reversible: true
is: ENSMMUG00000017873.2
product: 148577
reactant: 148529
reactant: 148505
product: 148625
product: 148601
reactant: 148493
notes: R_FATP9t subsystem: Transport, Extracellular R_FATP9t equation: na1[c] + nrvnc[c] <==> na1[e] + nrvnc[e] R_FATP7t subsystem: Transport, Extracellular R_FATP7t equation: crvnc[c] + na1[c] <==> crvnc[e] + na1[e] R_FATP4t subsystem: Transport, Extracellular R_FATP4t equation: arach[c] + na1[c] <==> arach[e] + na1[e] R_FATP5t subsystem: Transport, Extracellular R_FATP5t equation: arachd[c] + na1[c] <==> arachd[e] + na1[e] R_FATP6t subsystem: Transport, Extracellular R_FATP6t equation: adrn[c] + na1[c] <==> adrn[e] + na1[e] R_FATP8t subsystem: Transport, Extracellular R_FATP8t equation: lgnc[c] + na1[c] <==> lgnc[e] + na1[e]
product: 148565
reactant: 148553
product: 148613
type: Reaction

053122
stoichiometry: 1.0
species: 039873
type: SpeciesReference

092173
stoichiometry: 1.0
species: 026880
type: SpeciesReference

100650
stoichiometry: 1.0
species: 040270
type: SpeciesReference

091836
stoichiometry: 1.0
species: 024010
type: SpeciesReference

036691
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 7_C210H337N15O181S10
type: Species

064874
stoichiometry: 1.0
species: 034179
type: SpeciesReference

072271
stoichiometry: 1.0
species: 036173
type: SpeciesReference

083711
stoichiometry: 1.0
species: 030199
type: SpeciesReference

068790
stoichiometry: 18.0
species: 033094
type: SpeciesReference

115080
stoichiometry: 1.0
species: 036281
type: SpeciesReference

133716
stoichiometry: 1.0
species: 025903
type: SpeciesReference

119826
stoichiometry: 1.0
species: 046779
type: SpeciesReference

073797
stoichiometry: 35.0
species: 034448
type: SpeciesReference

926333
reactant: 072307
notes: R_PIter subsystem: Transport, Endoplasmic Reticular R_PIter equation: pi[r] <==> pi[c] R_G6Pter subsystem: Transport, Endoplasmic Reticular R_G6Pter equation: g6p[c] <==> g6p[r]
product: 072331
type: Reaction
reactant: 072295
product: 072319
fast: false
is: ENSMMUG00000016890.2
reversible: true

042956
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Proline_C5H9NO2
type: Species

044971
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Thiocyanate_CNS
type: Species

039837
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Malonate semialdehyde_C3H3O3
type: Species

025891
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Biotinyl-5'-AMP_C20H27N7O9PS
type: Species

093655
stoichiometry: 1.0
species: 025541
type: SpeciesReference

021243
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: trans-4-Hydroxy-L-proline_C5H9NO3
type: Species

023865
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: O-Acetylcarnitine_C9H17NO4
type: Species

079589
stoichiometry: 1.0
species: 042115
type: SpeciesReference

062801
stoichiometry: 1.0
species: 024731
type: SpeciesReference

925384
reactant: 064417
fast: false
reactant: 064429
reactant: 064404
reactant: 064392
product: 064477
product: 064453
is: ENSMMUG00000005835.2
is: ENSMMUG00000021931.2
is: http://identifiers.org/ec-code/1.2.3.1
type: Reaction
reversible: false
product: 064465
product: 064441
notes: R_PYDXDH subsystem: Vitamin B6 Metabolism R_PYDXDH equation: [c] : h2o + o2 + pydx --> 4pyrdx + h2o2 R_5HOXINDACTO2OX subsystem: Tryptophan metabolism R_5HOXINDACTO2OX equation: [c] : 5hoxindact + h2o + o2 --> 5hoxindoa + h + h2o2

108462
stoichiometry: 1.0
species: 042283
type: SpeciesReference

124724
stoichiometry: 1.0
species: 039667
type: SpeciesReference

090262
stoichiometry: 1.0
species: 026420
type: SpeciesReference

932293
product: 129850
product: 129886
reactant: 129802
is: ENSMMUG00000017561.2
notes: R_METtec subsystem: Transport, Extracellular R_METtec equation: met-L[e] <==> met-L[c] R_ILEtec subsystem: Transport, Extracellular R_ILEtec equation: ile-L[e] <==> ile-L[c] R_CYStec subsystem: Transport, Extracellular R_CYStec equation: cys-L[e] <==> cys-L[c] R_LEUtec subsystem: Transport, Extracellular R_LEUtec equation: leu-L[e] <==> leu-L[c] R_VALtec subsystem: Transport, Extracellular R_VALtec equation: val-L[e] <==> val-L[c] R_PHEtec subsystem: Transport, Extracellular R_PHEtec equation: phe-L[e] <==> phe-L[c]
product: 129898
product: 129874
reactant: 129814
reversible: true
product: 129838
reactant: 129777
fast: false
reactant: 129826
type: Reaction
reactant: 129789
reactant: 129765
product: 129862

037524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 10_C89H143N7O69S2X
type: Species

097263
stoichiometry: 1.0
species: 031097
type: SpeciesReference

084156
stoichiometry: 1.0
species: 047333
type: SpeciesReference

082214
stoichiometry: 1.0
species: 032597
type: SpeciesReference

923704
fast: false
reactant: 048826
is: http://identifiers.org/ec-code/1.2.3.5
product: 048923
reactant: 048863
product: 048911
modifier: 048995
product: 048935
is: ENSMMUG00000022037.2
modifier: 048959
reactant: 048850
type: Reaction
modifier: 048983
modifier: 048947
reactant: 048875
reactant: 048838
product: 048899
reversible: false
reactant: 048814
is: http://identifiers.org/ec-code/1.1.1.28
product: 048887
notes: R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_LDH_D subsystem: Pyruvate Metabolism R_LDH_D equation: [c] : lac-D + nad <==> h + nadh + pyr
modifier: 048971

034412
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: H+_H
type: Species

033785
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GQ1b (homo sapiens)_C88H143N6O54FULLRCO
type: Species

123013
stoichiometry: 1.0
species: 041319
type: SpeciesReference

047081
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _3alpha,7alpha,26-Trihydroxy-5beta-cholestane_C27H48O3
type: Species

098789
stoichiometry: 1.0
species: 040753
type: SpeciesReference

094003
stoichiometry: 1.0
species: 034363
type: SpeciesReference

122605
stoichiometry: 3.0
species: 028521
type: SpeciesReference

043091
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Prostaglandin E2_C20H31O5
type: Species

083278
stoichiometry: 1.0
species: 042343
type: SpeciesReference

022027
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

089585
stoichiometry: 1.0
species: 037621
type: SpeciesReference

069237
stoichiometry: 1.0
species: 024853
type: SpeciesReference

067607
stoichiometry: 1.0
species: 034327
type: SpeciesReference

045621
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Thymidine_C10H14N2O5
type: Species

061034
stoichiometry: 1.0
species: 046067
type: SpeciesReference

931909
is: ENSMMUG00000022155.2
type: Reaction
notes: R_PRGNLONESULT subsystem: Steroid Metabolism R_PRGNLONESULT equation: [c] : paps + prgnlone --> h + pap + prgnlones R_CHSTEROLSULT subsystem: Steroid Metabolism R_CHSTEROLSULT equation: [c] : chsterol + paps --> chsterols + h + pap
product: 126303
reactant: 126255
reactant: 126243
reactant: 126267
fast: false
product: 126291
reversible: false
product: 126279
product: 126315
is: http://identifiers.org/ec-code/2.8.2.2

933219
reactant: 138278
notes: R_PIACGT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_PIACGT equation: [c] : pail_hs + uacgam --> acgpail_hs + h + udp R_DOLPMT_L subsystem: N-Glycan Biosynthesis R_DOLPMT_L equation: [c] : (0.1) dolp_L + gdpmann --> (0.1) dolmanp_L + gdp R_DOLPMT_U subsystem: N-Glycan Biosynthesis R_DOLPMT_U equation: [c] : (0.1) dolp_U + gdpmann --> (0.1) dolmanp_U + gdp
reactant: 138326
type: Reaction
reversible: false
product: 138362
product: 138350
is: ENSMMUG00000014374.2
reactant: 138314
is: http://identifiers.org/ec-code/2.4.1.198
product: 138338
is: http://identifiers.org/ec-code/2.4.1.83
product: 138386
product: 138374
reactant: 138290
product: 138398
reactant: 138302
fast: false

102494
stoichiometry: 1.0
species: 041681
type: SpeciesReference

113163
stoichiometry: 1.0
species: 037778
type: SpeciesReference

046488
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: UMP_C9H11N2O9P
type: Species

113791
stoichiometry: 1.0
species: 037004
type: SpeciesReference

057999
stoichiometry: 1.0
species: 035762
type: SpeciesReference

100674
stoichiometry: 1.0
species: 040198
type: SpeciesReference

027037
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: CMP-N-acetylneuraminate_C20H29N4O16P
type: Species

120765
stoichiometry: 2.0
species: 040849
type: SpeciesReference

132932
stoichiometry: 1.0
species: 041995
type: SpeciesReference

082649
stoichiometry: 1.0
species: 034253
type: SpeciesReference

070901
stoichiometry: 1.0
species: 028644
type: SpeciesReference

027783
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 3_C31H48NO32S2
type: Species

930421
is: http://identifiers.org/ec-code/2.7.7.22
is: ENSMMUG00000014584.2
notes: R_MAN1PT2 subsystem: Fructose and Mannose Metabolism R_MAN1PT2 equation: [c] : gdp + h + man1p --> gdpmann + pi
is: ENSMMUG00000017938.2
product: 110837
reactant: 110812
reactant: 110800
fast: false
reactant: 110825
reversible: false
type: Reaction
name: mannose-1-phosphate guanylyltransferase (GDP)
product: 110849

139376
stoichiometry: 1.0
species: 044174
type: SpeciesReference

043163
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Prostaglandin H2_C20H31O5
type: Species

077870
stoichiometry: 3.0
species: 021835
type: SpeciesReference

152029
stoichiometry: 1.0
species: 046151
type: SpeciesReference

127329
stoichiometry: 1.0
species: 043692
type: SpeciesReference

930764
product: 114563
product: 114551
product: 114575
reversible: false
reactant: 114539
is: http://identifiers.org/ec-code/3.1.2.4
name: _3-hydroxyisobutyryl-Coenzyme A hydrolase
notes: R_3HPCOAHYD subsystem: beta-Alanine metabolism R_3HPCOAHYD equation: [c] : 3hpcoa + h2o --> 3hpp + coa + h
fast: false
reactant: 114527
is: ENSMMUG00000007283.2
type: Reaction

143273
stoichiometry: 1.0
species: 036533
type: SpeciesReference

126665
stoichiometry: 1.0
species: 046391
type: SpeciesReference

139097
stoichiometry: 1.0
species: 040029
type: SpeciesReference

027181
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Coenzyme A_C21H32N7O16P3S
type: Species

022498
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-Acetylserotonin_C12H14N2O2
type: Species

044247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-sulfolactate_C3H4O6S
type: Species

067547
stoichiometry: 1.0
species: 034436
type: SpeciesReference

923656
product: 048524
type: Reaction
name: Hydroxymethylglutaryl CoA synthase (ir)
is: http://identifiers.org/ec-code/4.1.3.5
product: 048512
is: ENSMMUG00000006948.1
fast: false
reactant: 048488
is: ENSMMUG00000001226.2
notes: R_HMGCOASi subsystem: Cholesterol Metabolism R_HMGCOASi equation: [c] : aacoa + accoa + h2o --> coa + h + hmgcoa
product: 048500
reactant: 048476
reactant: 048464
reversible: false

093052
stoichiometry: 6.0
species: 028656
type: SpeciesReference

151679
stoichiometry: 2.0
species: 025541
type: SpeciesReference

149933
stoichiometry: 3.0
species: 034363
type: SpeciesReference

052048
stoichiometry: 1.0
species: 030953
type: SpeciesReference

091980
stoichiometry: 1.0
species: 034665
type: SpeciesReference

123373
stoichiometry: 4.0
species: 042295
type: SpeciesReference

151054
stoichiometry: 1.0
species: 040789
type: SpeciesReference

140737
stoichiometry: 3.0
species: 026977
type: SpeciesReference

107943
stoichiometry: 1.0
species: 038562
type: SpeciesReference

087956
stoichiometry: 1.0
species: 042103
type: SpeciesReference

038887
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X
type: Species

095535
stoichiometry: 1.0
species: 026408
type: SpeciesReference

093775
stoichiometry: 3.0
species: 025541
type: SpeciesReference

141692
stoichiometry: 3.0
species: 040017
type: SpeciesReference

036824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 15_C149H240N10O119S4X
type: Species

927377
type: Reaction
modifier: 081719
is: ENSMMUG00000014891.2
fast: false
modifier: 081743
reactant: 081647
product: 081707
product: 081671
reversible: false
notes: R_CBPSam subsystem: Glutamate metabolism R_CBPSam equation: [m] : (2) atp + hco3 + nh4 --> (2) adp + cbp + (2) h + pi R_H2CO3D subsystem: Miscellaneous R_H2CO3D equation: [c] : co2 + h2o <==> h2co3
reactant: 081635
product: 081683
is: http://identifiers.org/ec-code/6.3.4.16
product: 081695
reactant: 081659
modifier: 081731
is: http://identifiers.org/ec-code/4.2.1.1

039140
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Mannose 6-phosphate_C6H11O9P
type: Species

066798
stoichiometry: 1.0
species: 037886
type: SpeciesReference

928746
reactant: 095691
reactant: 095643
reactant: 095619
reactant: 095631
notes: R_CITRtm subsystem: Transport, Mitochondrial R_CITRtm equation: citr-L[m] <==> citr-L[c] R_ORNt3m subsystem: Transport, Mitochondrial R_ORNt3m equation: h[c] + orn[m] <==> h[m] + orn[c] R_ARGtm subsystem: Transport, Mitochondrial R_ARGtm equation: arg-L[c] + h[m] <==> arg-L[m] + h[c] R_ORNt4m subsystem: Transport, Mitochondrial R_ORNt4m equation: citr-L[c] + h[c] + orn[m] <==> citr-L[m] + h[m] + orn[c] R_LYStm subsystem: Transport, Mitochondrial R_LYStm equation: h[m] + lys-L[c] <==> h[c] + lys-L[m]
product: 095775
product: 095739
product: 095751
reactant: 095679
product: 095715
reversible: true
fast: false
is: ENSMMUG00000022585.2
product: 095763
reactant: 095667
product: 095727
product: 095703
is: ENSMMUG00000021943.1
reactant: 095655
type: Reaction

924580
name: _5-aminolevulinate synthase
product: 056732
fast: false
reversible: false
product: 056744
is: ENSMMUG00000008429.2
type: Reaction
product: 056720
is: http://identifiers.org/ec-code/2.3.1.37
reactant: 056696
reactant: 056708
reactant: 056684
is: ENSMMUG00000005596.2
notes: R_ALASm subsystem: Glycine, Serine, and Threonine Metabolism R_ALASm equation: [m] : gly + h + succoa --> 5aop + co2 + coa

136483
stoichiometry: 1.0
species: 033628
type: SpeciesReference

132052
stoichiometry: 1.0
species: 020289
type: SpeciesReference

107088
stoichiometry: 1.0
species: 035762
type: SpeciesReference

147491
stoichiometry: 1.0
species: 043536
type: SpeciesReference

028571
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dATP_C10H12N5O12P3
type: Species

098056
stoichiometry: 1.0
species: 020240
type: SpeciesReference

136603
stoichiometry: 1.0
species: 029692
type: SpeciesReference

110245
stoichiometry: 1.0
species: 035532
type: SpeciesReference

143801
stoichiometry: 1.0
species: 032428
type: SpeciesReference

104150
stoichiometry: 1.0
species: 024010
type: SpeciesReference

041717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Palmitoyl-ACP (n-C16:0ACP)_C27H51N2O8PRS
type: Species

021979
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

932859
fast: false
reversible: false
type: Reaction
reactant: 135385
product: 135457
reactant: 135409
product: 135469
is: ENSMMUG00000009192.2
reactant: 135421
product: 135433
reactant: 135397
is: ENSMMUG00000016567.2
notes: R_GLXO2p subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO2p equation: [x] : glx + h2o + o2 --> h + h2o2 + oxa R_GLYCTO1p subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLYCTO1p equation: [x] : glyclt + o2 --> glx + h2o2
product: 135445

131230
stoichiometry: 1.0
species: 037112
type: SpeciesReference

081335
stoichiometry: 1.0
species: 030953
type: SpeciesReference

095259
stoichiometry: 1.0
species: 023235
type: SpeciesReference

932437
product: 132196
reversible: false
product: 132232
type: Reaction
product: 132220
reactant: 132148
product: 132208
reactant: 132172
reactant: 132160
product: 132244
is: ENSMMUG00000010797.2
reactant: 132184
notes: R_BMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_L equation: [r] : (0.1) dolmanp_L + memgacpail_hs --> (0.1) dolp_L + h + m2emgacpail_hs R_BMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_U equation: [r] : (0.1) dolmanp_U + memgacpail_hs --> (0.1) dolp_U + h + m2emgacpail_hs R_H3MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_L equation: [r] : (0.1) dolmanp_L + m2gacpail_hs --> (0.1) dolp_L + h + m3gacpail_hs R_H3MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_U equation: [r] : (0.1) dolmanp_U + m2gacpail_hs --> (0.1) dolp_U + h + m3gacpail_hs
fast: false

076592
stoichiometry: 1.0
species: 037802
type: SpeciesReference

044479
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Sphingosine 1-phosphate_C18H37NO5P
type: Species

133173
stoichiometry: 1.0
species: 041006
type: SpeciesReference

929083
reactant: 097984
is: ENSMMUG00000004574.2
reactant: 097996
product: 098008
name: phosphate transport in/out via Na+ symporter
product: 098020
notes: R_PIt8 subsystem: Transport, Extracellular R_PIt8 equation: (1.5) na1[e] + pi[e] <==> (1.5) na1[c] + pi[c]
type: Reaction
is: ENSMMUG00000020186.2
fast: false
reversible: true

030224
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: dTDP_C10H13N2O11P2
type: Species

149713
stoichiometry: 1.0
species: 041393
type: SpeciesReference

071765
stoichiometry: 1.0
species: 044717
type: SpeciesReference

133028
stoichiometry: 1.0
species: 040390
type: SpeciesReference

148348
stoichiometry: 1.0
species: 028547
type: SpeciesReference

080094
stoichiometry: 1.0
species: 027145
type: SpeciesReference

096335
stoichiometry: 1.0
species: 024250
type: SpeciesReference

094584
stoichiometry: 2.0
species: 032184
type: SpeciesReference

078307
stoichiometry: 1.0
species: 035519
type: SpeciesReference

090865
stoichiometry: 1.0
species: 025541
type: SpeciesReference

052387
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species: 019659
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species: 034520
type: SpeciesReference

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species: 025541
type: SpeciesReference

072840
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species: 027338
type: SpeciesReference

077037
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species: 046623
type: SpeciesReference

095211
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species: 023235
type: SpeciesReference

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species: 045887
type: SpeciesReference

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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: N-Trimethyl-2-aminoethylphosphonate_C5H13NO3P
type: Species

137773
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species: 043066
type: SpeciesReference

121728
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species: 034399
type: SpeciesReference

039402
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: L-Methionine_C5H11NO2S
type: Species

102169
stoichiometry: 1.0
species: 027218
type: SpeciesReference

139351
stoichiometry: 1.0
species: 045585
type: SpeciesReference

094439
stoichiometry: 1.0
species: 041175
type: SpeciesReference

142041
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species: 019241
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Pyruvate_C3H3O3
type: Species

139206
stoichiometry: 1.0
species: 030042
type: SpeciesReference

141040
stoichiometry: 1.0
species: 037717
type: SpeciesReference

135879
stoichiometry: 1.0
species: 038803
type: SpeciesReference

110897
stoichiometry: 1.0
species: 028704
type: SpeciesReference

107232
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species: 031931
type: SpeciesReference

132076
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species: 034315
type: SpeciesReference

019900
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-2-Amino-3-oxobutanoate_C4H7NO3
type: Species

119681
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species: 045008
type: SpeciesReference

138929
stoichiometry: 1.0
species: 041657
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934456
modifier: 151463
modifier: 151535
fast: false
reversible: false
modifier: 151475
modifier: 151595
modifier: 151643
modifier: 151607
modifier: 151571
modifier: 151547
modifier: 151487
modifier: 151511
modifier: 151499
modifier: 151655
modifier: 151619
reactant: 151439
type: Reaction
modifier: 151583
is: ENSMMUG00000022685.2
modifier: 151559
modifier: 151523
modifier: 151631
product: 151451
notes: R_ADNt subsystem: Transport, Extracellular R_ADNt equation: adn[e] <==> adn[c] R_ADNtm subsystem: Transport, Mitochondrial R_ADNtm equation: adn[c] <==> adn[m] R_INSt subsystem: Transport, Extracellular R_INSt equation: ins[e] <==> ins[c] R_URIt subsystem: Transport, Extracellular R_URIt equation: uri[e] <==> uri[c] R_GSNt subsystem: Transport, Extracellular R_GSNt equation: gsn[e] <==> gsn[c] R_GSNtm subsystem: Transport, Mitochondrial R_GSNtm equation: gsn[c] <==> gsn[m] R_Uritm subsystem: Transport, Mitochondrial R_Uritm equation: uri[c] <==> uri[m] R_CYTDtm subsystem: Transport, Mitochondrial R_CYTDtm equation: cytd[c] <==> cytd[m] R_INStm subsystem: Transport, Mitochondrial R_INStm equation: ins[c] <==> ins[m] R_THYMDtm subsystem: Transport, Mitochondrial R_THYMDtm equation: thymd[c] <==> thymd[m] R_THYMDt1 subsystem: Transport, Extracellular R_THYMDt1 equation: thymd[e] --> thymd[c] R_CYTDt subsystem: Transport, Extracellular R_CYTDt equation: cytd[e] <==> cytd[c]

089706
stoichiometry: 1.0
species: 036920
type: SpeciesReference

143405
stoichiometry: 1.0
species: 036509
type: SpeciesReference

035181
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 17_C43H65N2O48S4
type: Species

074543
stoichiometry: 1.0
species: 034532
type: SpeciesReference

142632
stoichiometry: 1.0
species: 040198
type: SpeciesReference

107968
stoichiometry: 1.0
species: 030734
type: SpeciesReference

114419
stoichiometry: 1.0
species: 022969
type: SpeciesReference

088064
stoichiometry: 16.0
species: 032923
type: SpeciesReference

036956
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 25_C199H319N14O163S7X
type: Species

077230
stoichiometry: 2.0
species: 034253
type: SpeciesReference

121404
stoichiometry: 1.0
species: 041573
type: SpeciesReference

931333
notes: R_METS subsystem: Methionine Metabolism R_METS equation: [c] : 5mthf + hcys-L --> h + met-L + thf
product: 121644
reactant: 121620
reactant: 121608
product: 121656
name: methionine synthase
fast: false
is: ENSMMUG00000010073.2
reversible: false
type: Reaction
is: http://identifiers.org/ec-code/2.1.1.13
product: 121632

099971
stoichiometry: 1.0
species: 031037
type: SpeciesReference

046271
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: UDP_C9H11N2O12P2
type: Species

058325
stoichiometry: 1.0
species: 026771
type: SpeciesReference

022619
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: R total 2 position_CO2FULLR2
type: Species

053639
stoichiometry: 2.0
species: 025541
type: SpeciesReference

086145
stoichiometry: 1.0
species: 030734
type: SpeciesReference

079262
stoichiometry: 1.0
species: 032124
type: SpeciesReference

042259
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: phytanyl coa_C41H70N7O17P3S
type: Species

049383
stoichiometry: 1.0
species: 046488
type: SpeciesReference

060373
stoichiometry: 1.0
species: 034303
type: SpeciesReference

056878
stoichiometry: 1.0
species: 033529
type: SpeciesReference

027990
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 1_C45H65N2O52S5
type: Species

059073
stoichiometry: 1.0
species: 034653
type: SpeciesReference

131823
stoichiometry: 1.0
species: 037426
type: SpeciesReference

ORG:
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n:
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145176
stoichiometry: 1.0
species: 036643
type: SpeciesReference

082553
stoichiometry: 1.0
species: 029643
type: SpeciesReference

102699
stoichiometry: 1.0
species: 034412
type: SpeciesReference

067752
stoichiometry: 1.0
species: 030904
type: SpeciesReference

113633
stoichiometry: 1.0
species: 040849
type: SpeciesReference

102265
stoichiometry: 1.0
species: 034869
type: SpeciesReference

085083
stoichiometry: 1.0
species: 040282
type: SpeciesReference

022256
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: heptaglutamyl folate (THF)_C49H57N13O24
type: Species

032282
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: nLc8Cer_C72H125N4O42FULLRCO
type: Species

112995
stoichiometry: 11.0
species: 046343
type: SpeciesReference

110306
stoichiometry: 1.0
species: 019498
type: SpeciesReference

115808
stoichiometry: 2.0
species: 034303
type: SpeciesReference

116438
stoichiometry: 1.0
species: 021026
type: SpeciesReference

070297
stoichiometry: 1.0
species: 037874
type: SpeciesReference

930215
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type: Reaction
reactant: 108137
modifier: 108209
is: http://identifiers.org/ec-code/2.7.7.18
modifier: 108197
reactant: 108125
product: 108149
modifier: 108185
reversible: false
modifier: 108257
modifier: 108233
modifier: 108221
reactant: 108113
product: 108161
is: http://identifiers.org/ec-code/2.7.7.1
is: ENSMMUG00000000287.2
product: 108173
modifier: 108245
fast: false
reactant: 108101

085228
stoichiometry: 1.0
species: 034363
type: SpeciesReference

095968
stoichiometry: 1.0
species: 043030
type: SpeciesReference

033554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: ganglioside GM1 (homo sapiens)_C55H95N3O30FULLRCO
type: Species

074711
stoichiometry: 1.0
species: 039414
type: SpeciesReference

126243
stoichiometry: 1.0
species: 042752
type: SpeciesReference

050396
stoichiometry: 1.0
species: 026904
type: SpeciesReference

134652
stoichiometry: 1.0
species: 023926
type: SpeciesReference

075653
stoichiometry: 1.0
species: 035677
type: SpeciesReference

077967
stoichiometry: 2.0
species: 042283
type: SpeciesReference

118907
stoichiometry: 1.0
species: 022632
type: SpeciesReference

033034
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Glutamine_C5H10N2O3
type: Species

069827
stoichiometry: 2.0
species: 042283
type: SpeciesReference

082879
stoichiometry: 1.0
species: 024561
type: SpeciesReference

098488
stoichiometry: 1.0
species: 025227
type: SpeciesReference

150946
stoichiometry: 1.0
species: 034277
type: SpeciesReference

133881
stoichiometry: 4.0
species: 034363
type: SpeciesReference

027326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Coproporphyrinogen III_C36H40N4O8
type: Species

019241
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19
type: Species

147263
stoichiometry: 1.0
species: 030710
type: SpeciesReference

119124
stoichiometry: 1.0
species: 019791
type: SpeciesReference

090031
stoichiometry: 1.0
species: 020216
type: SpeciesReference

117824
stoichiometry: 1.0
species: 029994
type: SpeciesReference

055380
stoichiometry: 1.0
species: 028497
type: SpeciesReference

069007
stoichiometry: 1.0
species: 042331
type: SpeciesReference

037220
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate II (core 2-linked), degradation product 3_C58H94N5O46S2X
type: Species

128317
stoichiometry: 1.0
species: 044162
type: SpeciesReference

924712
reactant: 057661
type: Reaction
product: 057697
fast: false
notes: R_TKT2 subsystem: Pentose Phosphate Pathway R_TKT2 equation: [c] : e4p + xu5p-D <==> f6p + g3p R_TKT1 subsystem: Pentose Phosphate Pathway R_TKT1 equation: [c] : r5p + xu5p-D <==> g3p + s7p
reversible: true
is: http://identifiers.org/ec-code/2.2.1.1
is: ENSMMUG00000013667.2
is: ENSMMUG00000003388.1
reactant: 057649
reactant: 057637
product: 057685
is: ENSMMUG00000014433.2
product: 057673

151883
stoichiometry: 3.0
species: 027218
type: SpeciesReference

072828
stoichiometry: 1.0
species: 024365
type: SpeciesReference

103342
stoichiometry: 1.0
species: 036017
type: SpeciesReference

057131
stoichiometry: 2.0
species: 023490
type: SpeciesReference

927161
is: http://identifiers.org/ec-code/2.1.1.8
type: Reaction
reactant: 079142
reactant: 079130
is: ENSMMUG00000007849.2
notes: R_SAMHISTA subsystem: Histidine Metabolism R_SAMHISTA equation: [c] : amet + hista --> ahcys + h + mhista
fast: false
product: 079154
is: ENSMMUG00000006918.2
reversible: false
name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase
product: 079178
product: 079166

128197
stoichiometry: 1.0
species: 022051
type: SpeciesReference

113900
stoichiometry: 1.0
species: 037088
type: SpeciesReference

084362
stoichiometry: 2.0
species: 040366
type: SpeciesReference

046043
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Thiosulfate_O3S2
type: Species

020870
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3-Phospho-D-glycerate_C3H4O7P
type: Species

148360
stoichiometry: 7.0
species: 034253
type: SpeciesReference

109465
stoichiometry: 1.0
species: 029247
type: SpeciesReference

145443
stoichiometry: 1.0
species: 027858
type: SpeciesReference

147683
stoichiometry: 1.0
species: 028993
type: SpeciesReference

083807
stoichiometry: 1.0
species: 030224
type: SpeciesReference

036113
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Itaconate_C5H4O4
type: Species

055645
stoichiometry: 1.0
species: 030892
type: SpeciesReference

141149
stoichiometry: 8.0
species: 034363
type: SpeciesReference

926777
reversible: false
product: 076375
reactant: 076158
reactant: 076218
product: 076387
fast: false
product: 076291
reactant: 076242
is: ENSMMUG00000003102.2
is: http://identifiers.org/ec-code/2.7.2.11
product: 076315
reactant: 076170
product: 076303
product: 076399
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_G5SDym subsystem: Urea cycle/amino group metabolism R_G5SDym equation: [m] : glu5p + h + nadph --> glu5sa + nadp + pi R_GLU5Km subsystem: Urea cycle/amino group metabolism R_GLU5Km equation: [m] : atp + glu-L --> adp + glu5p R_AGPRim subsystem: Urea cycle/amino group metabolism R_AGPRim equation: [m] : acg5p + h + nadph --> acg5sa + nadp + pi R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh
is: http://identifiers.org/ec-code/1.2.1.41
reactant: 076230
product: 076363
product: 076339
reactant: 076206
reactant: 076194
type: Reaction
is: http://identifiers.org/ec-code/1.2.1.21
product: 076351
product: 076327
reactant: 076254
reactant: 076145
product: 076279
reactant: 076267
reactant: 076182
is: http://identifiers.org/ec-code/1.2.1.38

089416
stoichiometry: 1.0
species: 037064
type: SpeciesReference

045417
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO
type: Species

041102
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Octadecynoyl-ACP (n-C18:2ACP)_C29H51N2O8PRS
type: Species

930972
type: Reaction
is: ENSMMUG00000002677.2
reactant: 117462
fast: false
product: 117498
reactant: 117486
reactant: 117474
reversible: false
product: 117534
product: 117510
notes: R_GAL3ST11 subsystem: Sphingolipid Metabolism R_GAL3ST11 equation: [g] : galside_hs + paps --> h + pap + sgalside_hs R_GAL3ST12 subsystem: Sphingolipid Metabolism R_GAL3ST12 equation: [g] : digalside_hs + paps --> digalsgalside_hs + h + pap
is: http://identifiers.org/ec-code/2.8.2.11
product: 117522

104704
stoichiometry: 2.0
species: 034303
type: SpeciesReference

059816
stoichiometry: 1.0
species: 033082
type: SpeciesReference

074122
stoichiometry: 3.0
species: 024816
type: SpeciesReference

085734
stoichiometry: 1.0
species: 024949
type: SpeciesReference

061478
stoichiometry: 6.0
species: 027097
type: SpeciesReference

066474
stoichiometry: 1.0
species: 030430
type: SpeciesReference

129573
stoichiometry: 2.0
species: 034363
type: SpeciesReference

030042
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10
type: Species

053206
stoichiometry: 1.0
species: 034363
type: SpeciesReference

028559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: dAMP_C10H12N5O6P
type: Species

057058
stoichiometry: 2.0
species: 034387
type: SpeciesReference

082443
stoichiometry: 1.0
species: 028473
type: SpeciesReference

064729
stoichiometry: 1.0
species: 027037
type: SpeciesReference

147479
stoichiometry: 1.0
species: 040162
type: SpeciesReference

124953
stoichiometry: 2.0
species: 024034
type: SpeciesReference

108089
stoichiometry: 4.0
species: 034363
type: SpeciesReference

047742
stoichiometry: 1.0
species: 032584
type: SpeciesReference

035581
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 9_C87H129N5O69X
type: Species

099428
stoichiometry: 2.0
species: 023162
type: SpeciesReference

039993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: N4-Acetylaminobutanal_C6H11NO2
type: Species

057359
stoichiometry: 1.0
species: 033785
type: SpeciesReference

932149
type: Reaction
reversible: false
reactant: 128438
notes: R_DOLPGT3_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT3_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g2m8mpdol_L --> (0.1) dolp_L + (0.1) g3m8mpdol_L + h R_DOLPGT3_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT3_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g2m8mpdol_U --> (0.1) dolp_U + (0.1) g3m8mpdol_U + h
product: 128486
product: 128510
reactant: 128462
reactant: 128450
is: ENSMMUG00000001214.2
reactant: 128474
product: 128498
product: 128534
product: 128522
fast: false

038465
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _5alpha-Cholest-7-en-3beta-ol_C27H46O
type: Species

079794
stoichiometry: 1.0
species: 022474
type: SpeciesReference

060962
stoichiometry: 1.0
species: 020484
type: SpeciesReference

029235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4
type: Species

038188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: linoelaidyl coenzyme A_C39H62N7O17P3S
type: Species

131570
stoichiometry: 1.0
species: 032500
type: SpeciesReference

065175
stoichiometry: 1.0
species: 041319
type: SpeciesReference

059181
stoichiometry: 1.0
species: 045153
type: SpeciesReference

139797
stoichiometry: 1.0
species: 024034
type: SpeciesReference

930868
is: ENSMMUG00000030292.1
fast: false
product: 116510
notes: R_NTD1m subsystem: Nucleotides R_NTD1m equation: [m] : dump + h2o --> duri + pi R_NTD5m subsystem: Nucleotides R_NTD5m equation: [m] : dtmp + h2o --> pi + thymd R_NTD2m subsystem: Nucleotides R_NTD2m equation: [m] : h2o + ump --> pi + uri
type: Reaction
is: http://identifiers.org/ec-code/3.1.3.5
reactant: 116486
product: 116534
reversible: false
reactant: 116450
reactant: 116474
reactant: 116462
product: 116498
product: 116522

035013
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: heptadecanoate_C17H33O2
type: Species

097491
stoichiometry: 1.0
species: 026710
type: SpeciesReference

068198
stoichiometry: 2.0
species: 044283
type: SpeciesReference

042788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: pregnenolone sulfate_C21H31O5S
type: Species

052858
stoichiometry: 1.0
species: 041657
type: SpeciesReference

066101
stoichiometry: 3.0
species: 040017
type: SpeciesReference

040474
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Nicotinate D-ribonucleotide_C11H12NO9P
type: Species

142403
stoichiometry: 1.0
species: 019277
type: SpeciesReference

128946
stoichiometry: 1.0
species: 038742
type: SpeciesReference

103753
stoichiometry: 1.0
species: 039511
type: SpeciesReference

068005
stoichiometry: 1.0
species: 030491
type: SpeciesReference

057915
stoichiometry: 1.0
species: 033094
type: SpeciesReference

071993
stoichiometry: 5.0
species: 040198
type: SpeciesReference

099127
stoichiometry: 1.0
species: 041934
type: SpeciesReference

105055
stoichiometry: 1.0
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product: 082745
product: 082709
reactant: 082697
reactant: 082673
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product: 082757
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type: Reaction
is: http://identifiers.org/ec-code/3.1.3.46
is: ENSMMUG00000008425.2
notes: R_FBP26 subsystem: Fructose and Mannose Metabolism R_FBP26 equation: [c] : f26bp + h2o --> f6p + pi R_PFK26 subsystem: Fructose and Mannose Metabolism R_PFK26 equation: [c] : atp + f6p --> adp + f26bp + h
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product: 082733
product: 082721
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924400
product: 054760
is: http://identifiers.org/ec-code/2.4.2.2
is: ENSMMUG00000007037.2
reversible: true
type: Reaction
product: 054748
name: pyrimidine-nucleoside phosphorylase (uracil)
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reactant: 054723

931921
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reactant: 126339
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reactant: 126327
type: Reaction
reversible: true
product: 126363
name: glutathione peridoxase
product: 126351
is: http://identifiers.org/ec-code/1.11.1.9

075242
stoichiometry: 4.0
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137217
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species: 046235
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933664
product: 142789
modifier: 142873
modifier: 142861
modifier: 142849
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product: 142813
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product: 142777
reactant: 142765
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modifier: 142825
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928422
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product: 093125
product: 093137
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species: 034581
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117078
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species: 037766
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boundary condition: false
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species: 040270
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type: SpeciesReference

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species: 024365
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stoichiometry: 1.0
species: 025927
type: SpeciesReference

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species: 021787
type: SpeciesReference

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species: 022607
type: SpeciesReference

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species: 027590
type: SpeciesReference

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species: 039176
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078537
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type: SpeciesReference

132606
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type: SpeciesReference

062102
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reactant: 097143
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product: 097203
product: 097191
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reactant: 097131
product: 097167
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name: Propionyl-CoA carboxylase, mitochondrial
product: 097179
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035338
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initial amount: NaN
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8
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species: 030649
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species: 034363
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boundary condition: false
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species: 037693
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species: 041982
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type: SpeciesReference

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species: 033821
type: SpeciesReference

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boundary condition: false
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054134
stoichiometry: 1.0
species: 038923
type: SpeciesReference

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species: 040693
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type: SpeciesReference

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species: 044839
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species: 040077
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024130
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species: 041754
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type: SpeciesReference

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species: 031592
type: SpeciesReference

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species: 025469
type: SpeciesReference

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type: SpeciesReference

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species: 045633
type: SpeciesReference

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species: 041465
type: SpeciesReference

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species: 024034
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species: 031121
type: SpeciesReference

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species: 035495
type: SpeciesReference

052483
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species: 020070
type: SpeciesReference

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type: SpeciesReference

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type: SpeciesReference

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species: 033712
type: SpeciesReference

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species: 028668
type: SpeciesReference

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boundary condition: false
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initial amount: NaN
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stoichiometry: 1.0
species: 024365
type: SpeciesReference

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constant: false
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initial amount: NaN
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148637
stoichiometry: 1.0
species: 038032
type: SpeciesReference

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stoichiometry: 12.0
species: 040150
type: SpeciesReference

085662
stoichiometry: 1.0
species: 043512
type: SpeciesReference

027482
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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058204
stoichiometry: 1.0
species: 024561
type: SpeciesReference

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stoichiometry: 1.0
species: 032923
type: SpeciesReference

148782
stoichiometry: 2.0
species: 027181
type: SpeciesReference

053978
stoichiometry: 4.0
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type: SpeciesReference

930095
product: 107316
reactant: 107304
product: 107328
reactant: 107280
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notes: R_HSD11B1r subsystem: Steroid Metabolism R_HSD11B1r equation: [r] : cortsn + h + nadph <==> crtsl + nadp
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reversible: true
reactant: 107292
type: Reaction

924004
reactant: 051552
name: threonine synthase
type: Reaction
notes: R_THRS subsystem: Glycine, Serine, and Threonine Metabolism R_THRS equation: [c] : h2o + phom --> pi + thr-L
is: http://identifiers.org/ec-code/4.2.3.1
product: 051588
reactant: 051564
is: ENSMMUG00000022383.2
fast: false
reversible: false
product: 051576

032088
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: (alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1905H3140N20O770P20
type: Species

075350
stoichiometry: 1.0
species: 026359
type: SpeciesReference

142186
stoichiometry: 1.0
species: 021991
type: SpeciesReference

039263
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (mannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (B)_C45H84N2O27P2FULLRCO2FULLR2CO2
type: Species

102181
stoichiometry: 1.0
species: 022994
type: SpeciesReference

110535
stoichiometry: 1.0
species: 024658
type: SpeciesReference

927581
product: 083314
reactant: 083302
notes: R_EGMESTr subsystem: Alkaloid biosynthesis II R_EGMESTr equation: [r] : egme + h2o --> ecgon + h + meoh
reactant: 083290
type: Reaction
is: ENSMMUG00000001664.2
product: 083338
product: 083326
name: ecgonine methyl esterase (ER)
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fast: false

077218
stoichiometry: 1.0
species: 041597
type: SpeciesReference

103645
stoichiometry: 1.0
species: 022522
type: SpeciesReference

121692
stoichiometry: 1.0
species: 046235
type: SpeciesReference

083927
stoichiometry: 1.0
species: 030309
type: SpeciesReference

100238
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species: 042283
type: SpeciesReference

065813
stoichiometry: 1.0
species: 033082
type: SpeciesReference

079382
stoichiometry: 1.0
species: 042968
type: SpeciesReference

129140
stoichiometry: 1.0
species: 025541
type: SpeciesReference

929371
type: Reaction
notes: R_NNMT subsystem: NAD Metabolism R_NNMT equation: [c] : amet + ncam --> 1mncam + ahcys
reversible: false
product: 101626
reactant: 101614
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name: Nicotinamide N-methyltransferase
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is: http://identifiers.org/ec-code/2.1.1.1
reactant: 101602
product: 101638

127614
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species: 034363
type: SpeciesReference

022632
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boundary condition: false
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initial amount: NaN
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name: R total 2 coenzyme A_CO2FULLR2C21H31N7O15P3S
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062536
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species: 021460
type: SpeciesReference

105872
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species: 033203
type: SpeciesReference

020738
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: (S)-3-Methyl-2-oxopentanoate_C6H9O3
type: Species

135517
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species: 035193
type: SpeciesReference

048826
stoichiometry: 1.0
species: 035073
type: SpeciesReference

141378
stoichiometry: 1.0
species: 042283
type: SpeciesReference

111077
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species: 033870
type: SpeciesReference

110945
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species: 027169
type: SpeciesReference

037378
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boundary condition: false
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initial amount: NaN
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134219
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species: 034375
type: SpeciesReference

044681
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117534
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044307
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130335
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species: 033445
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059702
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type: SpeciesReference

149810
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species: 034253
type: SpeciesReference

035447
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124881
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148421
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species: 033846
type: SpeciesReference

137869
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type: SpeciesReference

076628
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species: 032597
type: SpeciesReference

114755
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species: 043885
type: SpeciesReference

070141
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species: 040198
type: SpeciesReference

025433
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boundary condition: false
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initial amount: NaN
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initial amount: NaN
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933087
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reactant: 137616
product: 137652
name: Cytochrome P450 11A1, mitochondrial [Precursor]
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reactant: 137604
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103110
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084566
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species: 025215
type: SpeciesReference

130783
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species: 021472
type: SpeciesReference

137436
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species: 034303
type: SpeciesReference

138821
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species: 034436
type: SpeciesReference

025733
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boundary condition: false
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initial amount: NaN
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reactant: 069959
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reactant: 069947
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099283
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species: 030892
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type: SpeciesReference

147191
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species: 047393
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species: 032246
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species: 032850
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species: 040270
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species: 033724
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product: 078537
product: 078561
product: 078525
type: Reaction
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reactant: 078489
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115917
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species: 035811
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species: 034253
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105487
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species: 045573
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is: ENSMMUG00000001592.2
is: ENSMMUG00000002929.2
is: ENSMMUG00000018526.2
is: ENSMMUG00000004447.2
is: ENSMMUG00000001553.2
fast: false
notes: R_NADH2_DASH_u10m subsystem: Oxidative Phosphorylation R_NADH2_DASH_u10m equation: (5) h[m] + nadh[m] + q10[m] --> (4) h[c] + nad[m] + q10h2[m]
reactant: 058470
is: ENSMMUG00000030508.1
is: ENSMMUG00000018897.2
is: ENSMMUG00000029347.1
is: ENSMMUG00000006636.2
product: 058506
is: ENSMMUG00000010090.2
is: ENSMMUG00000013060.2
is: ENSMMUG00000004520.2
is: ENSMMUG00000030210.1
is: ENSMMUG00000007657.2
name: NADH dehydrogenase, mitochondrial
is: ENSMMUG00000029268.1
is: ENSMMUG00000007068.2
is: ENSMMUG00000009746.2
is: ENSMMUG00000012225.1

923992
product: 051528
product: 051504
is: http://identifiers.org/ec-code/1.2.4.1
reversible: false
is: ENSMMUG00000006448.2
fast: false
product: 051540
reactant: 051468
reactant: 051480
reactant: 051456
is: http://identifiers.org/ec-code/1.2.4.2
product: 051492
reactant: 051444
product: 051516
notes: R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
type: Reaction
reactant: 051432

133440
stoichiometry: 1.0
species: 045959
type: SpeciesReference

102374
stoichiometry: 8.0
species: 040017
type: SpeciesReference

020009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _2-Hydroxybutyrate_C4H7O3
type: Species

098596
stoichiometry: 1.0
species: 034821
type: SpeciesReference

069719
stoichiometry: 1.0
species: 034253
type: SpeciesReference

039571
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3
type: Species

033664
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: GMP_C10H12N5O8P
type: Species

145745
stoichiometry: 2.0
species: 027918
type: SpeciesReference

044533
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Serotonin_C10H13N2O
type: Species

029346
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Dehydroascorbate_C6H6O6
type: Species

932991
name: GMP reductase
fast: false
is: ENSMMUG00000012455.2
reversible: false
is: ENSMMUG00000002936.2
reactant: 136495
type: Reaction
product: 136531
reactant: 136483
product: 136543
product: 136519
reactant: 136507
notes: R_GMPR subsystem: Nucleotides R_GMPR equation: [c] : gmp + (2) h + nadph --> imp + nadp + nh4
is: http://identifiers.org/ec-code/1.7.1.7

066582
stoichiometry: 1.0
species: 030249
type: SpeciesReference

126399
stoichiometry: 1.0
species: 021702
type: SpeciesReference

032172
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
type: Species

075939
stoichiometry: 1.0
species: 032004
type: SpeciesReference

076096
stoichiometry: 1.0
species: 041597
type: SpeciesReference

055754
stoichiometry: 1.0
species: 034253
type: SpeciesReference

930325
product: 110027
reactant: 110014
notes: R_FRUt1r subsystem: Transport, Extracellular R_FRUt1r equation: fru[e] <==> fru[c]
is: ENSMMUG00000003472.2
fast: false
reversible: true
name: D-fructose transport in via uniport
type: Reaction

111825
stoichiometry: 1.0
species: 047069
type: SpeciesReference

082661
stoichiometry: 1.0
species: 031085
type: SpeciesReference

033323
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Glyceraldehyde_C3H6O3
type: Species

047069
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al_C27H46O3
type: Species

145066
stoichiometry: 1.0
species: 036389
type: SpeciesReference

120465
stoichiometry: 1.0
species: 039571
type: SpeciesReference

028400
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Cytidine_C9H13N3O5
type: Species

147047
stoichiometry: 2.0
species: 019524
type: SpeciesReference

085191
stoichiometry: 1.0
species: 025541
type: SpeciesReference

036005
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: myo-Inositol_C6H12O6
type: Species

098861
stoichiometry: 1.0
species: 045153
type: SpeciesReference

029655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: dITP_C10H11N4O13P3
type: Species

927701
reactant: 085095
notes: R_GTHO subsystem: Glutamate metabolism R_GTHO equation: [c] : gthox + h + nadph --> (2) gthrd + nadp R_GTHOm subsystem: Glutamate metabolism R_GTHOm equation: [m] : gthox + h + nadph --> (2) gthrd + nadp
product: 085155
reactant: 085107
reactant: 085059
is: ENSMMUG00000016458.2
product: 085143
reactant: 085083
product: 085167
type: Reaction
product: 085131
is: http://identifiers.org/ec-code/1.8.1.7
reactant: 085119
fast: false
reactant: 085071
reversible: false

091547
stoichiometry: 3.0
species: 031181
type: SpeciesReference

113260
stoichiometry: 1.0
species: 021799
type: SpeciesReference

131931
stoichiometry: 1.0
species: 037124
type: SpeciesReference

138278
stoichiometry: 2.0
species: 032850
type: SpeciesReference

058965
stoichiometry: 1.0
species: 022849
type: SpeciesReference

038032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: lignoceric acid_C24H47O2
type: Species

094149
stoichiometry: 1.0
species: 034363
type: SpeciesReference

118330
stoichiometry: 1.0
species: 044234
type: SpeciesReference

052255
stoichiometry: 2.0
species: 034436
type: SpeciesReference

100008
stoichiometry: 1.0
species: 037790
type: SpeciesReference

116026
stoichiometry: 1.0
species: 034063
type: SpeciesReference

136819
stoichiometry: 1.0
species: 046791
type: SpeciesReference

147792
stoichiometry: 1.0
species: 033846
type: SpeciesReference

145334
stoichiometry: 1.0
species: 028002
type: SpeciesReference

934348
reactant: 150354
is: http://identifiers.org/ec-code/1.4.3.6
product: 150548
reversible: false
product: 150536
reactant: 150439
fast: false
reactant: 150342
reactant: 150367
type: Reaction
reactant: 150415
product: 150560
reactant: 150452
product: 150584
product: 150572
product: 150500
reactant: 150391
product: 150512
reactant: 150427
is: http://identifiers.org/ec-code/1.4.3.4
product: 150476
notes: R_PTRCOX1 subsystem: Arginine and Proline Metabolism R_PTRCOX1 equation: [c] : h2o + o2 + ptrc --> 4abutn + h2o2 + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_NMPTRCOX subsystem: Alkaloid biosynthesis II R_NMPTRCOX equation: [c] : nmptrc + o2 --> 1mpyr + h2o2 + nh4 R_MHISOR subsystem: Histidine Metabolism R_MHISOR equation: [c] : h2o + mhista + o2 --> 3mldz + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_HISTASE subsystem: Histidine Metabolism R_HISTASE equation: [c] : h2o + hista + o2 --> h2o2 + im4act + nh4 R_MAOX subsystem: Tyrosine metabolism R_MAOX equation: [c] : h2o + mma + o2 --> fald + h2o2 + nh4 R_13DAMPPOX subsystem: beta-Alanine metabolism R_13DAMPPOX equation: [c] : 13dampp + h2o + o2 --> bamppald + h2o2 + nh4
product: 150464
is: ENSMMUG00000020435.2
reactant: 150403
reactant: 150330
product: 150488
reactant: 150379
product: 150524

141258
stoichiometry: 3.0
species: 033119
type: SpeciesReference

136181
stoichiometry: 1.0
species: 034363
type: SpeciesReference

033251
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Glyoxylate_C2H1O3
type: Species

134544
stoichiometry: 1.0
species: 029933
type: SpeciesReference

047525
stoichiometry: 4.0
species: 029199
type: SpeciesReference

077857
stoichiometry: 3.0
species: 040657
type: SpeciesReference

083290
stoichiometry: 1.0
species: 030599
type: SpeciesReference

045827
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Reduced thioredoxin_XH2
type: Species

063634
stoichiometry: 1.0
species: 031568
type: SpeciesReference

026808
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Citrulline_C6H13N3O3
type: Species

071318
stoichiometry: 1.0
species: 034363
type: SpeciesReference

065284
stoichiometry: 1.0
species: 037609
type: SpeciesReference

105379
stoichiometry: 5.0
species: 028303
type: SpeciesReference

931813
type: Reaction
reactant: 125314
product: 125399
product: 125351
is: ENSMMUG00000018483.2
is: http://identifiers.org/ec-code/4.4.1.16
product: 125375
notes: R_SELCYSLY2 subsystem: Selenoamino acid metabolism R_SELCYSLY2 equation: [c] : pdx5p + selcys --> ala-L + h + pydx5p + seln R_SELCYSLY subsystem: Selenoamino acid metabolism R_SELCYSLY equation: [c] : dtt + selcys --> ala-L + dttOX + h + seln
product: 125363
reversible: false
fast: false
reactant: 125327
product: 125387
reactant: 125339

099537
stoichiometry: 2.0
species: 023066
type: SpeciesReference

928530
type: Reaction
product: 094053
is: ENSMMUG00000031829.1
reactant: 094041
product: 094077
is: ENSMMUG00000010695.2
fast: false
product: 094065
reactant: 094029
notes: R_FBA2 subsystem: Fructose and Mannose Metabolism R_FBA2 equation: [c] : f1p <==> dhap + glyald R_FBA subsystem: Glycolysis/Gluconeogenesis R_FBA equation: [c] : fdp <==> dhap + g3p R_FBA4 subsystem: Glyoxylate and Dicarboxylate Metabolism R_FBA4 equation: [c] : xu1p-D <==> dhap + gcald
is: http://identifiers.org/ec-code/4.1.2.13
is: ENSMMUG00000020322.2
reactant: 094016
product: 094089
reversible: true

060746
stoichiometry: 1.0
species: 029994
type: SpeciesReference

024352
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8
type: Species

047899
stoichiometry: 2.0
species: 023066
type: SpeciesReference

071680
stoichiometry: 1.0
species: 023610
type: SpeciesReference

092052
stoichiometry: 1.0
species: 038296
type: SpeciesReference

114875
stoichiometry: 1.0
species: 037862
type: SpeciesReference

925648
is: ENSMMUG00000020406.2
reactant: 067135
reversible: false
product: 067183
is: http://identifiers.org/ec-code/2.4.1.102
fast: false
reactant: 067147
product: 067195
product: 067207
type: Reaction
reactant: 067159
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp R_CORE6GTg subsystem: O-Glycan Biosynthesis R_CORE6GTg equation: [g] : Tn_antigen + uacgam --> core6 + h + udp
product: 067171

073178
stoichiometry: 1.0
species: 025927
type: SpeciesReference

926621
fast: false
is: ENSMMUG00000019488.2
notes: R_F1PGT subsystem: Fructose and Mannose Metabolism R_F1PGT equation: [c] : fuc1p-L + gtp + h <==> gdpfuc + ppi
is: http://identifiers.org/ec-code/2.7.7.30
product: 075083
reactant: 075059
type: Reaction
product: 075096
reversible: true
name: fucose-1-phosphate guanylyltransferase
reactant: 075071
reactant: 075047

053315
stoichiometry: 1.0
species: 040077
type: SpeciesReference

094294
stoichiometry: 1.0
species: 042536
type: SpeciesReference

090443
stoichiometry: 1.0
species: 024202
type: SpeciesReference

060481
stoichiometry: 1.0
species: 040162
type: SpeciesReference

049273
stoichiometry: 1.0
species: 046731
type: SpeciesReference

027882
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 3_C37H54NO41S3
type: Species

128838
stoichiometry: 1.0
species: 041393
type: SpeciesReference

050504
stoichiometry: 2.0
species: 045754
type: SpeciesReference

060890
stoichiometry: 2.0
species: 034363
type: SpeciesReference

082334
stoichiometry: 1.0
species: 030212
type: SpeciesReference

058421
stoichiometry: 1.0
species: 040270
type: SpeciesReference

110752
stoichiometry: 2.0
species: 034363
type: SpeciesReference

071885
stoichiometry: 1.0
species: 039225
type: SpeciesReference

121247
stoichiometry: 1.0
species: 030042
type: SpeciesReference

135733
stoichiometry: 1.0
species: 044162
type: SpeciesReference

100383
stoichiometry: 1.0
species: 032753
type: SpeciesReference

926477
product: 073701
product: 073713
is: http://identifiers.org/ec-code/4.2.1.17
product: 073640
reactant: 073335
reactant: 073432
modifier: 073845
product: 073773
modifier: 073893
product: 073591
product: 073725
product: 073603
reactant: 073419
modifier: 073869
reactant: 073579
modifier: 073918
product: 073749
reactant: 073395
reactant: 073359
product: 073809
reactant: 073469
product: 073785
reactant: 073519
reactant: 073531
reactant: 073456
reactant: 073506
product: 073797
product: 073821
reversible: false
is: http://identifiers.org/ec-code/1.3.99.3
reactant: 073323
modifier: 073930
fast: false
product: 073616
product: 073689
product: 073652
product: 073628
reactant: 073494
reactant: 073555
product: 073833
modifier: 073954
reactant: 073371
notes: R_PRPNCOAHYDx subsystem: beta-Alanine metabolism R_PRPNCOAHYDx equation: [x] : h2o + prpncoa --> 3hpcoa R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_ECOAH1x subsystem: Tryptophan metabolism R_ECOAH1x equation: [x] : 3hbcoa <==> b2coa + h2o R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_FAOXC260240x subsystem: Fatty acid oxidation, peroxisome R_FAOXC260240x equation: [x] : coa + h2o + hexccoa + nad + o2 --> accoa + h + h2o2 + lgnccoa + nadh R_C2M26DCOAHLx subsystem: Limonene and pinene degradation R_C2M26DCOAHLx equation: [x] : c2m2…
product: 073664
reactant: 073407
modifier: 073857
product: 073737
reactant: 073567
reactant: 073383
reactant: 073347
modifier: 073881
is: http://identifiers.org/ec-code/1.1.1.35
is: ENSMMUG00000005531.2
reactant: 073444
modifier: 073905
product: 073676
type: Reaction
product: 073761
reactant: 073482
reactant: 073543
modifier: 073942

096607
stoichiometry: 1.0
species: 043849
type: SpeciesReference

928314
reactant: 090865
product: 090901
reactant: 090889
product: 090925
notes: R_ARGSS subsystem: Alanine and Aspartate Metabolism R_ARGSS equation: [c] : asp-L + atp + citr-L --> amp + argsuc + h + ppi
is: http://identifiers.org/ec-code/6.3.4.5
name: argininosuccinate synthase
product: 090913
reversible: false
fast: false
product: 090937
is: ENSMMUG00000018468.2
reactant: 090877
type: Reaction

048139
stoichiometry: 1.0
species: 035387
type: SpeciesReference

034063
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: GTP_C10H12N5O14P3
type: Species

079057
stoichiometry: 1.0
species: 034253
type: SpeciesReference

140520
stoichiometry: 1.0
species: 037766
type: SpeciesReference

021811
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Hydroxy-N-formylkynurenine_C11H12N2O5
type: Species

040620
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Normetanephrine_C9H14NO3
type: Species

074447
stoichiometry: 4.0
species: 044295
type: SpeciesReference

137109
stoichiometry: 2.0
species: 045741
type: SpeciesReference

933940
reactant: 147191
reactant: 147203
product: 147239
name: xylulose reductase
notes: R_XYLUR subsystem: Pentose and Glucuronate Interconversions R_XYLUR equation: [c] : h + nadph + xylu-L <==> nadp + xylt
reversible: true
type: Reaction
product: 147227
fast: false
is: http://identifiers.org/ec-code/1.1.1.10
is: ENSMMUG00000010896.2
reactant: 147215

137652
stoichiometry: 1.0
species: 021316
type: SpeciesReference

102024
stoichiometry: 1.0
species: 041886
type: SpeciesReference

096212
stoichiometry: 1.0
species: 041730
type: SpeciesReference

925240
type: Reaction
product: 062801
notes: R_GPAMm_hs subsystem: Triacylglycerol Synthesis R_GPAMm_hs equation: [m] : Rtotalcoa + glyc3p --> alpa_hs + coa R_GPAM_hs subsystem: Triacylglycerol Synthesis R_GPAM_hs equation: [c] : Rtotalcoa + glyc3p --> alpa_hs + coa
product: 062837
fast: false
reversible: false
reactant: 062777
product: 062825
reactant: 062789
reactant: 062753
is: ENSMMUG00000007526.2
reactant: 062765
product: 062813
is: http://identifiers.org/ec-code/2.3.1.15

114539
stoichiometry: 1.0
species: 034253
type: SpeciesReference

142970
stoichiometry: 1.0
species: 042151
type: SpeciesReference

049104
stoichiometry: 1.0
species: 034265
type: SpeciesReference

078753
stoichiometry: 1.0
species: 019949
type: SpeciesReference

128619
stoichiometry: 1.0
species: 033821
type: SpeciesReference

078814
stoichiometry: 1.0
species: 040017
type: SpeciesReference

077437
stoichiometry: 1.0
species: 033445
type: SpeciesReference

148855
stoichiometry: 2.0
species: 040162
type: SpeciesReference

107112
stoichiometry: 2.0
species: 034363
type: SpeciesReference

931050
product: 118052
product: 118076
is: ENSMMUG00000017445.2
reversible: false
reactant: 118040
is: http://identifiers.org/ec-code/3.1.1.1
name: Carboxylesterase (cocaine) (er)
fast: false
product: 118064
type: Reaction
is: ENSMMUG00000022825.2
reactant: 118028
notes: R_COKECBESr subsystem: Alkaloid biosynthesis II R_COKECBESr equation: [r] : coke + h2o --> bz + egme + h

110680
stoichiometry: 1.0
species: 034977
type: SpeciesReference

142511
stoichiometry: 1.0
species: 025251
type: SpeciesReference

063923
stoichiometry: 1.0
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species: 038670
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species: 042295
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product: 105800
product: 105740
reactant: 105704
product: 105788
reactant: 105692
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is: ENSMMUG00000019956.2

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species: 024853
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species: 034363
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boundary condition: false
has only substance units: false
initial concentration: NaN
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145891
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species: 028062
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species: 040102
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species: 019524
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reversible: false
name: lactoylglutathione lyase
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is: ENSMMUG00000001638.2
notes: R_LGTHL subsystem: Pyruvate Metabolism R_LGTHL equation: [c] : gthrd + mthgxl --> lgt-S
reactant: 049574
is: http://identifiers.org/ec-code/4.4.1.5
reactant: 049586
type: Reaction

108366
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species: 042331
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083073
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species: 044971
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087511
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species: 034363
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species: 031121
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has only substance units: false
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initial amount: NaN
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name: N-Acetylneuraminate 9-phosphate_C11H17NO12P
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species: 034689
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boundary condition: false
has only substance units: false
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boundary condition: false
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067849
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product: 099524
modifier: 099815
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modifier: 099791

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species: 045729
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species: 040029
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species: 045225
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initial amount: NaN
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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063200
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species: 040150
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071463
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has only substance units: false
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061154
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species: 042379
type: SpeciesReference

125906
stoichiometry: 3.0
species: 023490
type: SpeciesReference

073070
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species: 034303
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species: 040102
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species: 046415
type: SpeciesReference

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119705
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species: 045177
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species: 031109
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species: 045537
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932582
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product: 133245
product: 133293
reactant: 133137
type: Reaction
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product: 133257
product: 133233
reactant: 133209
reactant: 133149
modifier: 133416
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reactant: 133112
product: 133317
product: 133221
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product: 133305
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reactant: 133185
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is: http://identifiers.org/ec-code/2.3.1.86
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modifier: 133366
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065067
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species: 033021
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is: ENSMMUG00000008169.2
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product: 112152
is: ENSMMUG00000008642.2
notes: R_MI145PK subsystem: Inositol Phosphate Metabolism R_MI145PK equation: [c] : atp + mi145p --> adp + h + mi1345p
product: 112140
reactant: 112115
name: inositol-1,4,5-trisphosphate 3-kinase
reactant: 112128
product: 112164
reversible: false
type: Reaction
fast: false

033107
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: L-Glutamate_C5H8NO4
type: Species

107534
stoichiometry: 3.0
species: 033082
type: SpeciesReference

029078
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: dGMP_C10H12N5O7P
type: Species

060529
stoichiometry: 2.0
species: 047117
type: SpeciesReference

093558
stoichiometry: 1.0
species: 044162
type: SpeciesReference

ORG:
  orgname: University of Missouri
n:
  given: Michaël
  family: Bekaert

071535
stoichiometry: 1.0
species: 042295
type: SpeciesReference

116244
stoichiometry: 10.0
species: 034253
type: SpeciesReference

096903
stoichiometry: 4.0
species: 027218
type: SpeciesReference

934180
reversible: false
fast: false
product: 149362
is: http://identifiers.org/ec-code/1.5.99.1
notes: R_SARDHm subsystem: Urea cycle/amino group metabolism R_SARDHm equation: [m] : fad + sarcs + thf --> fadh2 + gly + mlthf
product: 149337
is: ENSMMUG00000017210.2
reactant: 149325
name: Sarcosine dehydrogenase (m)
type: Reaction
product: 149349
reactant: 149301
reactant: 149313

022039
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

069225
stoichiometry: 1.0
species: 025288
type: SpeciesReference

131243
stoichiometry: 1.0
species: 023586
type: SpeciesReference

045633
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Thymidine_C10H14N2O5
type: Species

039824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol, human uterine homolog_C1245H2040N20O220P20
type: Species

093979
stoichiometry: 1.0
species: 042283
type: SpeciesReference

089573
stoichiometry: 1.0
species: 036956
type: SpeciesReference

103560
stoichiometry: 1.0
species: 045729
type: SpeciesReference

033773
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: glycophosphatidylinositol (GPI) signal sequence (C-terminal peptide)_Y
type: Species

123025
stoichiometry: 1.0
species: 025118
type: SpeciesReference

139389
stoichiometry: 1.0
species: 042127
type: SpeciesReference

122617
stoichiometry: 1.0
species: 039583
type: SpeciesReference

126652
stoichiometry: 1.0
species: 038477
type: SpeciesReference

927858
fast: false
name: L-glutamate secretion via secretory vesicle (ATP driven)
type: Reaction
notes: R_GLUVESSEC subsystem: Transport, Extracellular R_GLUVESSEC equation: atp[c] + glu-L[c] + h2o[c] --> adp[c] + glu-L[e] + h[c] + pi[c]
product: 086108
is: ENSMMUG00000020368.2
is: ENSMMUG00000017646.2
product: 086096
is: ENSMMUG00000014800.2
reactant: 086084
reactant: 086060
reversible: false
product: 086132
product: 086120
reactant: 086072

100686
stoichiometry: 2.0
species: 019779
type: SpeciesReference

027049
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
type: Species

120777
stoichiometry: 1.0
species: 035653
type: SpeciesReference

027771
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 2_C37H55NO38S2
type: Species

132944
stoichiometry: 1.0
species: 027073
type: SpeciesReference

113151
stoichiometry: 1.0
species: 035774
type: SpeciesReference

933207
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D
name: hydroxyacylglutathione hydrolase
reactant: 138230
reactant: 138218
product: 138254
product: 138242
fast: false
is: http://identifiers.org/ec-code/3.1.2.6
is: ENSMMUG00000006453.2
reversible: false
type: Reaction
product: 138266

102482
stoichiometry: 5.0
species: 025541
type: SpeciesReference

043151
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Prostaglandin H2_C20H31O5
type: Species

027193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Coenzyme A_C21H32N7O16P3S
type: Species

040897
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Superoxide anion_O2
type: Species

022486
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-Acetyl-L-aspartate_C6H7NO5
type: Species

066690
stoichiometry: 1.0
species: 040029
type: SpeciesReference

044259
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Sulfite_O3S
type: Species

020459
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3-Hydroxyanthranilate_C7H7NO3
type: Species

130188
stoichiometry: 1.0
species: 035920
type: SpeciesReference

930647
reactant: 113392
notes: R_GMAND subsystem: Fructose and Mannose Metabolism R_GMAND equation: [c] : gdpmann --> gdpddman + h2o
is: http://identifiers.org/ec-code/4.2.1.47
name: GDP-D-mannose dehydratase
reversible: false
is: ENSMMUG00000018517.2
fast: false
type: Reaction
product: 113404
product: 113416

117980
stoichiometry: 1.0
species: 024010
type: SpeciesReference

930433
reactant: 110981
reactant: 110969
reactant: 110909
notes: R_NTD7l subsystem: Nucleic acid degradation R_NTD7l equation: [l] : amp + h2o --> adn + pi R_NTD9l subsystem: Nucleic acid degradation R_NTD9l equation: [l] : gmp + h2o --> gsn + pi R_NTD4l subsystem: Nucleic acid degradation R_NTD4l equation: [l] : cmp + h2o --> cytd + pi R_NTD3l subsystem: Nucleic acid degradation R_NTD3l equation: [l] : dcmp + h2o --> dcyt + pi R_NTD8l subsystem: Nucleic acid degradation R_NTD8l equation: [l] : dgmp + h2o --> dgsn + pi R_NTD2l subsystem: Nucleic acid degradation R_NTD2l equation: [l] : h2o + ump --> pi + uri R_LAPCOAl subsystem: CoA Catabolism R_LAPCOAl equation: [l] : coa + h2o --> dpcoa + pi R_NTD5l subsystem: Nucleic acid degradation R_NTD5l equation: [l] : dtmp + h2o --> pi + thymd R_3NTD7l subsystem: Nucleic acid degradation R_3NTD7l equation: [l] : 3amp + h2o --> adn + pi R_NTD6l subsystem: Nucleic acid degradation R_NTD6l equation: [l] : damp + h2o --> dad-2 + pi
product: 111029
product: 110993
product: 111065
product: 111077
reactant: 110933
product: 111101
reactant: 110945
product: 111005
fast: false
reactant: 110897
is: http://identifiers.org/ec-code/3.1.3.5
reactant: 110861
reversible: false
is: ENSMMUG00000015597.2
product: 111017
product: 111089
product: 111041
reactant: 110921
product: 111053
reactant: 110957
reactant: 110873
reactant: 110885
type: Reaction

152017
stoichiometry: 1.0
species: 045309
type: SpeciesReference

143285
stoichiometry: 1.0
species: 036679
type: SpeciesReference

127050
stoichiometry: 1.0
species: 030953
type: SpeciesReference

132497
stoichiometry: 1.0
species: 046355
type: SpeciesReference

929807
reversible: false
reactant: 104667
product: 104728
fast: false
reactant: 104643
is: ENSMMUG00000000001.2
reactant: 104692
notes: R_24_COMMA_25VITD3Hm subsystem: Vitamin D R_24_COMMA_25VITD3Hm equation: [m] : 25hvitd3 + h + nadph + o2 --> 2425dhvitd3 + h2o + nadp R_24_COMMA_25VITD2Hm subsystem: Vitamin D R_24_COMMA_25VITD2Hm equation: [m] : 25hvitd2 + h + nadph + o2 --> 2425dhvitd2 + h2o + nadp
product: 104740
reactant: 104655
type: Reaction
product: 104716
reactant: 104680
product: 104704

053423
stoichiometry: 2.0
species: 034363
type: SpeciesReference

150727
stoichiometry: 3.0
species: 024658
type: SpeciesReference

123361
stoichiometry: 1.0
species: 046671
type: SpeciesReference

122497
stoichiometry: 1.0
species: 041621
type: SpeciesReference

149921
stoichiometry: 1.0
species: 046403
type: SpeciesReference

151667
stoichiometry: 1.0
species: 043740
type: SpeciesReference

114202
stoichiometry: 1.0
species: 037572
type: SpeciesReference

139085
stoichiometry: 1.0
species: 034375
type: SpeciesReference

923644
reactant: 048428
fast: false
reactant: 048440
notes: R_LTA4H subsystem: Eicosanoid Metabolism R_LTA4H equation: [c] : h2o + leuktrA4 --> leuktrB4
name: Leukotriene A-4 hydrolase
reversible: false
product: 048452
type: Reaction
is: ENSMMUG00000009312.2
is: http://identifiers.org/ec-code/3.3.2.6

093064
stoichiometry: 9.0
species: 028644
type: SpeciesReference

124736
stoichiometry: 3.0
species: 034253
type: SpeciesReference

100518
stoichiometry: 1.0
species: 025565
type: SpeciesReference

934072
product: 148445
reactant: 148336
is: ENSMMUG00000003749.2
fast: false
product: 148433
product: 148385
product: 148409
reactant: 148324
reactant: 148360
product: 148469
product: 148421
product: 148397
reactant: 148373
is: http://identifiers.org/ec-code/3.1.3.5
reversible: false
product: 148457
reactant: 148312
reactant: 148348
reactant: 148288
reactant: 148300
type: Reaction
notes: R_NT5C subsystem: NAD Metabolism R_NT5C equation: [c] : h2o + nicrnt --> nicrns + pi R_NTD9 subsystem: Nucleotides R_NTD9 equation: [c] : gmp + h2o --> gsn + pi R_NTD6 subsystem: Nucleotides R_NTD6 equation: [c] : damp + h2o --> dad-2 + pi R_NTD11 subsystem: Purine Catabolism R_NTD11 equation: [c] : h2o + imp --> ins + pi R_NTD10 subsystem: Nucleotides R_NTD10 equation: [c] : h2o + xmp --> pi + xtsn R_NTD8 subsystem: Nucleotides R_NTD8 equation: [c] : dgmp + h2o --> dgsn + pi R_NTD7 subsystem: Nucleotides R_NTD7 equation: [c] : amp + h2o --> adn + pi

104921
stoichiometry: 1.0
species: 032258
type: SpeciesReference

090250
stoichiometry: 3.0
species: 031193
type: SpeciesReference

031895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)3 (Glc)1 (GlcNAc)1 (LFuc)2 (Cer)1_C62H109N2O35FULLRCO
type: Species

085517
stoichiometry: 3.0
species: 034412
type: SpeciesReference

054821
stoichiometry: 1.0
species: 039237
type: SpeciesReference

084217
stoichiometry: 1.0
species: 040077
type: SpeciesReference

064886
stoichiometry: 1.0
species: 031217
type: SpeciesReference

072283
stoichiometry: 1.0
species: 026832
type: SpeciesReference

039849
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Methylglyoxal_C3H4O2
type: Species

088618
stoichiometry: 1.0
species: 040065
type: SpeciesReference

115092
stoichiometry: 1.0
species: 037220
type: SpeciesReference

092161
stoichiometry: 1.0
species: 046779
type: SpeciesReference

100662
stoichiometry: 1.0
species: 044367
type: SpeciesReference

091824
stoichiometry: 1.0
species: 041393
type: SpeciesReference

023877
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: O-Acetylcarnitine_C9H17NO4
type: Species

053110
stoichiometry: 1.0
species: 046199
type: SpeciesReference

067535
stoichiometry: 1.0
species: 040789
type: SpeciesReference

931705
reactant: 124640
reactant: 124616
fast: false
is: http://identifiers.org/ec-code/3.6.3.10
product: 124652
notes: R_HKt subsystem: Transport, Extracellular R_HKt equation: atp[c] + h2o[c] + k[e] --> adp[c] + h[e] + k[c] + pi[c]
is: ENSMMUG00000007425.2
reversible: false
product: 124664
reactant: 124628
product: 124676
is: ENSMMUG00000031570.1
product: 124688
name: H+/K+ gastric/non-gastric P-ATPase and ABC ATPase
type: Reaction
is: ENSMMUG00000000845.2

146708
stoichiometry: 1.0
species: 044355
type: SpeciesReference

079577
stoichiometry: 1.0
species: 024646
type: SpeciesReference

061046
stoichiometry: 6.0
species: 027145
type: SpeciesReference

093667
stoichiometry: 1.0
species: 041621
type: SpeciesReference

125157
stoichiometry: 1.0
species: 041657
type: SpeciesReference

021255
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: trans-4-Hydroxy-L-proline_C5H9NO3
type: Species

925396
product: 064633
product: 064561
product: 064597
reactant: 064489
product: 064573
is: ENSMMUG00000021434.2
reactant: 064549
notes: R_ACCOACm subsystem: Fatty Acid Metabolism R_ACCOACm equation: [m] : accoa + atp + hco3 --> adp + h + malcoa + pi R_ACCOAC subsystem: Fatty Acid Metabolism R_ACCOAC equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi
product: 064609
product: 064645
reactant: 064525
reversible: false
product: 064621
reactant: 064537
reactant: 064501
is: http://identifiers.org/ec-code/6.4.1.2
product: 064585
type: Reaction
reactant: 064513
fast: false

094705
stoichiometry: 2.0
species: 040029
type: SpeciesReference

073785
stoichiometry: 2.0
species: 045754
type: SpeciesReference

042944
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: D-Proline_C5H9NO2
type: Species

926321
type: Reaction
reactant: 072259
product: 072271
reactant: 072247
fast: false
reversible: true
product: 072283
is: ENSMMUG00000016553.2
name: K+-Cl- cotransport
notes: R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]

026916
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: clupanodonyl carnitine_C29H47NO4
type: Species

119814
stoichiometry: 1.0
species: 043283
type: SpeciesReference

097275
stoichiometry: 1.0
species: 021811
type: SpeciesReference

082226
stoichiometry: 1.0
species: 033457
type: SpeciesReference

084144
stoichiometry: 1.0
species: 043777
type: SpeciesReference

135661
stoichiometry: 1.0
species: 025541
type: SpeciesReference

106161
stoichiometry: 1.0
species: 020882
type: SpeciesReference

108474
stoichiometry: 1.0
species: 024010
type: SpeciesReference

037512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate II (core 4-linked)_C89H142N7O72S3X
type: Species

065969
stoichiometry: 1.0
species: 020690
type: SpeciesReference

095223
stoichiometry: 1.0
species: 020045
type: SpeciesReference

119693
stoichiometry: 1.0
species: 030624
type: SpeciesReference

043476
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Pyruvate_C3H3O3
type: Species

078197
stoichiometry: 1.0
species: 028908
type: SpeciesReference

133729
stoichiometry: 1.0
species: 042524
type: SpeciesReference

139218
stoichiometry: 2.0
species: 039263
type: SpeciesReference

077025
stoichiometry: 1.0
species: 046635
type: SpeciesReference

143573
stoichiometry: 1.0
species: 045669
type: SpeciesReference

137761
stoichiometry: 2.0
species: 040270
type: SpeciesReference

052375
stoichiometry: 3.0
species: 040174
type: SpeciesReference

040777
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-(omega)-Hydroxyarginine_C6H15N4O3
type: Species

139363
stoichiometry: 1.0
species: 033034
type: SpeciesReference

094596
stoichiometry: 1.0
species: 030042
type: SpeciesReference

039414
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5,10-Methenyltetrahydrofolate_C20H20N7O6
type: Species

121716
stoichiometry: 1.0
species: 022945
type: SpeciesReference

934468
reactant: 151667
fast: false
reversible: false
product: 151703
reactant: 151679
product: 151715
is: ENSMMUG00000014458.2
reactant: 151691
notes: R_RBK subsystem: Pentose Phosphate Pathway R_RBK equation: [c] : atp + rib-D --> adp + h + r5p R_DRBK subsystem: Pentose Phosphate Pathway R_DRBK equation: [c] : atp + drib --> 2dr5p + adp + h
product: 151727
product: 151739
is: http://identifiers.org/ec-code/2.7.1.15
type: Reaction

035193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 18_C43H66N2O45S3
type: Species

143417
stoichiometry: 1.0
species: 036293
type: SpeciesReference

089718
stoichiometry: 1.0
species: 037016
type: SpeciesReference

132088
stoichiometry: 1.0
species: 020325
type: SpeciesReference

107220
stoichiometry: 1.0
species: 031919
type: SpeciesReference

062258
stoichiometry: 1.0
species: 032923
type: SpeciesReference

931345
is: ENSMMUG00000019177.2
product: 121704
is: ENSMMUG00000003735.2
is: http://identifiers.org/ec-code/2.4.1.41
product: 121716
reversible: false
is: ENSMMUG00000020815.2
type: Reaction
is: ENSMMUG00000017717.2
is: ENSMMUG00000016728.2
is: ENSMMUG00000013106.2
is: ENSMMUG00000012238.2
is: ENSMMUG00000019561.2
product: 121692
is: ENSMMUG00000003474.2
reactant: 121668
is: ENSMMUG00000022690.2
name: GalNAc transferase, Golgi apparatus
fast: false
is: ENSMMUG00000010615.2
is: ENSMMUG00000003239.2
reactant: 121680
notes: R_GALNTg subsystem: O-Glycan Biosynthesis R_GALNTg equation: [g] : Ser/Thr + udpacgal --> Tn_antigen + h + udp
is: ENSMMUG00000023165.2

036968
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 26_C199H318N14O166S8X
type: Species

074555
stoichiometry: 1.0
species: 026844
type: SpeciesReference

142620
stoichiometry: 1.0
species: 034327
type: SpeciesReference

088076
stoichiometry: 1.0
species: 044633
type: SpeciesReference

143921
stoichiometry: 1.0
species: 026953
type: SpeciesReference

079274
stoichiometry: 1.0
species: 040198
type: SpeciesReference

113368
stoichiometry: 1.0
species: 032984
type: SpeciesReference

028704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: dCMP_C9H12N3O7P
type: Species

058313
stoichiometry: 1.0
species: 027145
type: SpeciesReference

026095
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Calcium_Ca
type: Species

128728
stoichiometry: 1.0
species: 026371
type: SpeciesReference

107955
stoichiometry: 1.0
species: 038610
type: SpeciesReference

086458
stoichiometry: 3.0
species: 041754
type: SpeciesReference

071233
stoichiometry: 1.0
species: 022861
type: SpeciesReference

036836
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 16_C157H253N11O124S4X
type: Species

095523
stoichiometry: 2.0
species: 034363
type: SpeciesReference

093763
stoichiometry: 1.0
species: 043404
type: SpeciesReference

927365
product: 081623
reactant: 081611
notes: R_MACACI subsystem: Tyrosine metabolism R_MACACI equation: [c] : 4mlacac --> 4fumacac
is: ENSMMUG00000020777.2
is: http://identifiers.org/ec-code/5.2.1.2
fast: false
reversible: false
name: maleylacetoacetate isomerase
type: Reaction

925696
is: ENSMMUG00000005990.2
product: 067427
fast: false
product: 067415
type: Reaction
notes: R_ST6GALNAC31 subsystem: Sphingolipid Metabolism R_ST6GALNAC31 equation: [g] : cmpacna + gm1b_hs --> cmp + gd1alpha_hs + h
reversible: false
product: 067403
name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
reactant: 067391
reactant: 067378
is: ENSMMUG00000005994.2

030212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dTDP_C10H13N2O11P2
type: Species

038899
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1780H2928N20O620P20
type: Species

087944
stoichiometry: 1.0
species: 026335
type: SpeciesReference

039152
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Mannose_C6H12O6
type: Species

151066
stoichiometry: 2.0
species: 034363
type: SpeciesReference

930751
product: 114491
notes: R_PDXPP subsystem: Vitamin B6 Metabolism R_PDXPP equation: [c] : h2o + pdx5p --> pi + pydxn R_PYDXPP subsystem: Vitamin B6 Metabolism R_PYDXPP equation: [c] : h2o + pydx5p --> pi + pydx R_HYPOE subsystem: Vitamin B6 Metabolism R_HYPOE equation: [c] : h2o + pyam5p --> pi + pydam
is: ENSMMUG00000003854.2
reactant: 114455
reversible: false
type: Reaction
reactant: 114443
reactant: 114467
reactant: 114431
fast: false
product: 114479
product: 114515
product: 114503

110233
stoichiometry: 5.0
species: 034387
type: SpeciesReference

086132
stoichiometry: 1.0
species: 034363
type: SpeciesReference

098044
stoichiometry: 1.0
species: 034857
type: SpeciesReference

025541
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: ATP_C10H12N5O13P3
type: Species

143813
stoichiometry: 1.0
species: 046391
type: SpeciesReference

136495
stoichiometry: 2.0
species: 034363
type: SpeciesReference

924592
product: 056829
reversible: false
product: 056841
product: 056805
is: http://identifiers.org/ec-code/3.1.1.3
is: ENSMMUG00000004712.2
reactant: 056756
notes: R_LPS2 subsystem: Triacylglycerol Synthesis R_LPS2 equation: [c] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS subsystem: Triacylglycerol Synthesis R_LPS equation: [c] : h2o + tag_hs --> Rtotal3 + dag_hs + h
product: 056793
reactant: 056780
type: Reaction
fast: false
product: 056817
reactant: 056768

928758
product: 095800
reactant: 095787
notes: R_MMMm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMMm equation: [m] : mmcoa-R <==> succoa
is: ENSMMUG00000002458.2
is: http://identifiers.org/ec-code/5.4.99.2
fast: false
reversible: true
name: methylmalonyl-CoA mutase
type: Reaction

132064
stoichiometry: 1.0
species: 034253
type: SpeciesReference

019512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _12 hydroxy arachidonic acid_C20H31O3
type: Species

932425
fast: false
reversible: false
product: 132100
product: 132136
type: Reaction
reactant: 132064
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PDE4n subsystem: Nucleotides R_PDE4n equation: [n] : 35cgmp + h2o --> gmp + h
reactant: 132088
reactant: 132052
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 132076
product: 132124
is: ENSMMUG00000022107.2
product: 132112

044467
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Sphingosine 1-phosphate_C18H37NO5P
type: Species

140811
stoichiometry: 1.0
species: 023297
type: SpeciesReference

058880
stoichiometry: 1.0
species: 046139
type: SpeciesReference

119280
stoichiometry: 1.0
species: 034363
type: SpeciesReference

021967
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

041705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2
type: Species

104162
stoichiometry: 1.0
species: 019598
type: SpeciesReference

932847
type: Reaction
fast: false
is: ENSMMUG00000009053.2
reversible: true
reactant: 135325
reactant: 135313
product: 135349
name: glycine reversible transport via sodium and chloride symport (3:1:1)
reactant: 135337
notes: R_GLYt7_LPAREN_311_RPAREN_r subsystem: Transport, Extracellular R_GLYt7_LPAREN_311_RPAREN_r equation: cl[e] + gly[e] + (3) na1[e] <==> cl[c] + gly[c] + (3) na1[c]
product: 135361
product: 135373

081323
stoichiometry: 1.0
species: 030807
type: SpeciesReference

133016
stoichiometry: 4.0
species: 026832
type: SpeciesReference

928206
type: Reaction
name: fatty acid electroneutral transport
notes: R_FATP1t subsystem: Transport, Extracellular R_FATP1t equation: hdca[c] + na1[c] <==> hdca[e] + na1[e]
product: 088991
reactant: 088979
reversible: true
is: ENSMMUG00000014148.2
fast: false
reactant: 088967
is: ENSMMUG00000019487.2
product: 089003

096323
stoichiometry: 2.0
species: 024792
type: SpeciesReference

090877
stoichiometry: 1.0
species: 026808
type: SpeciesReference

058518
stoichiometry: 4.0
species: 034363
type: SpeciesReference

047670
stoichiometry: 1.0
species: 027699
type: SpeciesReference

108606
stoichiometry: 6.0
species: 040270
type: SpeciesReference

929095
product: 098212
product: 098188
product: 098140
product: 098236
is: http://identifiers.org/ec-code/4.1.1.25
is: http://identifiers.org/ec-code/4.1.1.22
notes: R_5HXKYNDCL subsystem: Tryptophan metabolism R_5HXKYNDCL equation: [c] : 5hxkyn + h --> 5hxkynam + co2 R_HISDC subsystem: Histidine Metabolism R_HISDC equation: [c] : h + his-L --> co2 + hista R_TYRCBOX subsystem: Tyrosine metabolism R_TYRCBOX equation: [c] : h + tyr-L --> co2 + tym R_5HLTDL subsystem: Tryptophan metabolism R_5HLTDL equation: [c] : 5htrp + h --> co2 + srtn R_PHYCBOXL subsystem: Phenylalanine metabolism R_PHYCBOXL equation: [c] : h + phe-L --> co2 + peamn R_LTDCL subsystem: Tryptophan metabolism R_LTDCL equation: [c] : h + trp-L --> co2 + trypta R_3HXKYNDCL subsystem: Tryptophan metabolism R_3HXKYNDCL equation: [c] : h + hLkynr --> 3hxkynam + co2 R_3HLYTCL subsystem: Tyrosine metabolism R_3HLYTCL equation: [c] : 34dhphe + h --> co2 + dopa
is: http://identifiers.org/ec-code/4.1.1.28
reactant: 098068
reactant: 098044
reactant: 098080
product: 098224
product: 098164
reversible: false
reactant: 098104
reactant: 098056
reactant: 098092
reactant: 098128
product: 098200
type: Reaction
product: 098176
reactant: 098032
fast: false
reactant: 098116
product: 098152
is: ENSMMUG00000019991.2

133161
stoichiometry: 1.0
species: 042379
type: SpeciesReference

122071
stoichiometry: 1.0
species: 027097
type: SpeciesReference

071777
stoichiometry: 1.0
species: 024501
type: SpeciesReference

149701
stoichiometry: 1.0
species: 026432
type: SpeciesReference

090431
stoichiometry: 1.0
species: 025203
type: SpeciesReference

082346
stoichiometry: 1.0
species: 035836
type: SpeciesReference

055307
stoichiometry: 1.0
species: 023114
type: SpeciesReference

930191
product: 108005
reactant: 107919
reactant: 107955
product: 107980
reactant: 107931
fast: false
reversible: false
product: 107968
is: ENSMMUG00000011866.2
product: 107992
notes: R_H6ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6ET3er equation: [r] : m2emgacpail_hs + pe_hs --> dag_hs + em2emgacpail_hs R_H4ET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H4ET3er equation: [r] : m3gacpail_hs + pe_hs --> dag_hs + em3gacpail_hs R_M4CET3er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_M4CET3er equation: [r] : m3emgacpail_hs + pe_hs --> dag_hs + mem2emgacpail_hs
type: Reaction
reactant: 107943

052954
stoichiometry: 1.0
species: 041561
type: SpeciesReference

068778
stoichiometry: 1.0
species: 045453
type: SpeciesReference

146720
stoichiometry: 1.0
species: 034327
type: SpeciesReference

021219
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _4-Hydroxyphenylacetaldehyde_C8H8O2
type: Species

092040
stoichiometry: 1.0
species: 045177
type: SpeciesReference

023998
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Adenosylcobalamin_C72H100CoN18O17P
type: Species

099500
stoichiometry: 1.0
species: 037766
type: SpeciesReference

073142
stoichiometry: 1.0
species: 025855
type: SpeciesReference

931825
product: 125519
is: ENSMMUG00000006339.2
reactant: 125471
type: Reaction
reversible: false
fast: false
product: 125531
notes: R_ACTNMO subsystem: Pyruvate Metabolism R_ACTNMO equation: [c] : acetone + h + nadph + o2 --> acetol + h2o + nadp R_ETOHMO subsystem: Glycolysis/Gluconeogenesis R_ETOHMO equation: [c] : etoh + h + nadph + o2 --> acald + (2) h2o + nadp R_P4502E1 subsystem: CYP Metabolism R_P4502E1 equation: [c] : 4nph + h + nadph + o2 --> 24nph + h2o + nadp R_ACTLMO subsystem: Pyruvate Metabolism R_ACTLMO equation: [c] : acetol + h + nadph + o2 --> (2) h2o + mthgxl + nadp
reactant: 125483
product: 125495
product: 125543
reactant: 125411
product: 125555
reactant: 125459
reactant: 125435
reactant: 125423
reactant: 125447
product: 125507

139519
stoichiometry: 1.0
species: 042115
type: SpeciesReference

129500
stoichiometry: 1.0
species: 040572
type: SpeciesReference

031774
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO
type: Species

081419
stoichiometry: 1.0
species: 039402
type: SpeciesReference

119958
stoichiometry: 1.0
species: 038080
type: SpeciesReference

927209
reactant: 079649
reactant: 079637
product: 079722
fast: false
is: ENSMMUG00000032143.1
is: ENSMMUG00000019871.2
product: 079685
reactant: 079661
is: ENSMMUG00000016998.2
product: 079734
reactant: 079673
product: 079709
notes: R_FAH3 subsystem: CYP Metabolism R_FAH3 equation: [c] : h + hdca + nadph + o2 --> h2o + nadp + whhdca R_FAH1 subsystem: CYP Metabolism R_FAH1 equation: [c] : ddca + h + nadph + o2 --> h2o + nadp + whddca R_FAH2 subsystem: CYP Metabolism R_FAH2 equation: [c] : h + nadph + o2 + ttdca --> h2o + nadp + whttdca
product: 079697
reversible: false
reactant: 079625
type: Reaction
reactant: 079613

145491
stoichiometry: 1.0
species: 036425
type: SpeciesReference

132112
stoichiometry: 1.0
species: 034424
type: SpeciesReference

063622
stoichiometry: 4.0
species: 040017
type: SpeciesReference

128293
stoichiometry: 4.0
species: 034363
type: SpeciesReference

113972
stoichiometry: 1.0
species: 037028
type: SpeciesReference

135782
stoichiometry: 2.0
species: 038815
type: SpeciesReference

934024
is: http://identifiers.org/ec-code/1.1.1.27
modifier: 147972
modifier: 147996
reversible: false
is: ENSMMUG00000000336.2
modifier: 147960
modifier: 147912
modifier: 147984
product: 147876
is: http://identifiers.org/ec-code/1.2.3.5
fast: false
modifier: 148009
modifier: 147936
reactant: 147864
modifier: 147924
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
reactant: 147852
type: Reaction
modifier: 147948
product: 147900
product: 147888
reactant: 147840

145346
stoichiometry: 1.0
species: 036715
type: SpeciesReference

051576
stoichiometry: 1.0
species: 045573
type: SpeciesReference

118366
stoichiometry: 2.0
species: 034363
type: SpeciesReference

132750
stoichiometry: 1.0
species: 037874
type: SpeciesReference

119898
stoichiometry: 1.0
species: 038176
type: SpeciesReference

095090
stoichiometry: 1.0
species: 040390
type: SpeciesReference

094137
stoichiometry: 1.0
species: 024010
type: SpeciesReference

076411
stoichiometry: 2.0
species: 031339
type: SpeciesReference

020131
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _2-Oxoadipate_C6H6O5
type: Species

138242
stoichiometry: 1.0
species: 034014
type: SpeciesReference

146443
stoichiometry: 2.0
species: 041453
type: SpeciesReference

113296
stoichiometry: 1.0
species: 035981
type: SpeciesReference

927737
reactant: 085349
notes: R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_DHEASt subsystem: Transport, Extracellular R_DHEASt equation: dheas[e] + hco3[c] <==> dheas[c] + hco3[e]
is: ENSMMUG00000009126.2
reactant: 085361
fast: false
type: Reaction
product: 085409
reversible: true
reactant: 085373
product: 085385
product: 085397

081527
stoichiometry: 1.0
species: 024082
type: SpeciesReference

146119
stoichiometry: 4.0
species: 046235
type: SpeciesReference

059581
stoichiometry: 1.0
species: 034797
type: SpeciesReference

049407
stoichiometry: 5.0
species: 042295
type: SpeciesReference

047057
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _3alpha,7alpha-Dihydroxy-5beta-cholestane_C27H48O2
type: Species

066846
stoichiometry: 1.0
species: 040017
type: SpeciesReference

102795
stoichiometry: 2.0
species: 026771
type: SpeciesReference

124290
stoichiometry: 9.0
species: 034532
type: SpeciesReference

071849
stoichiometry: 1.0
species: 044633
type: SpeciesReference

126604
stoichiometry: 1.0
species: 032440
type: SpeciesReference

083145
stoichiometry: 1.0
species: 034881
type: SpeciesReference

131364
stoichiometry: 1.0
species: 023442
type: SpeciesReference

931429
reactant: 122159
fast: false
is: ENSMMUG00000010879.2
product: 122171
product: 122183
is: http://identifiers.org/ec-code/2.7.1.23
reversible: false
name: NAD kinase
notes: R_NADK subsystem: NAD Metabolism R_NADK equation: [c] : atp + nad --> adp + h + nadp
reactant: 122147
type: Reaction
product: 122195

116534
stoichiometry: 3.0
species: 042331
type: SpeciesReference

067679
stoichiometry: 1.0
species: 043211
type: SpeciesReference

064211
stoichiometry: 2.0
species: 024646
type: SpeciesReference

039583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3
type: Species

033652
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GMP_C10H12N5O8P
type: Species

069695
stoichiometry: 1.0
species: 041922
type: SpeciesReference

075047
stoichiometry: 1.0
species: 031641
type: SpeciesReference

930595
is: http://identifiers.org/ec-code/4.3.1.8
name: hydroxymethylbilane synthase
notes: R_HMBS subsystem: Heme Biosynthesis R_HMBS equation: [c] : h2o + (4) ppbng --> hmbil + (4) nh4
reactant: 112886
product: 112911
type: Reaction
product: 112898
is: ENSMMUG00000014866.2
reactant: 112874
reversible: false
fast: false

098584
stoichiometry: 1.0
species: 044693
type: SpeciesReference

085300
stoichiometry: 1.0
species: 034290
type: SpeciesReference

111438
stoichiometry: 1.0
species: 031846
type: SpeciesReference

127026
stoichiometry: 1.0
species: 030807
type: SpeciesReference

122376
stoichiometry: 1.0
species: 034412
type: SpeciesReference

150848
stoichiometry: 3.0
species: 028315
type: SpeciesReference

082903
stoichiometry: 1.0
species: 040270
type: SpeciesReference

087631
stoichiometry: 8.0
species: 034387
type: SpeciesReference

123313
stoichiometry: 1.0
species: 026965
type: SpeciesReference

136735
stoichiometry: 1.0
species: 041187
type: SpeciesReference

112357
stoichiometry: 1.0
species: 045621
type: SpeciesReference

102362
stoichiometry: 1.0
species: 034857
type: SpeciesReference

093185
stoichiometry: 1.0
species: 028098
type: SpeciesReference

149993
stoichiometry: 2.0
species: 034290
type: SpeciesReference

022159
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: hexaglutamyl folate (THF)_C44H51N12O21
type: Species

927065
product: 078621
reactant: 078597
fast: false
product: 078633
reactant: 078609
is: ENSMMUG00000014360.2
notes: R_S2T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T1g equation: [g] : cs_c,d,e_pre1 + paps --> cs_d_pre2 + h + pap R_S2T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T2g equation: [g] : cs_d_pre5 + paps --> cspg_d + h + pap R_S2T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T3g equation: [g] : cs_b_pre5 + paps --> cspg_b + h + pap
product: 078657
product: 078645
reactant: 078585
reactant: 078573
product: 078669
type: Reaction
reversible: false

043030
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Prostaglandin D2_C20H31O5
type: Species

105475
stoichiometry: 5.0
species: 045585
type: SpeciesReference

093859
stoichiometry: 2.0
species: 026107
type: SpeciesReference

050830
stoichiometry: 4.0
species: 034436
type: SpeciesReference

075193
stoichiometry: 1.0
species: 024465
type: SpeciesReference

097347
stoichiometry: 1.0
species: 041150
type: SpeciesReference

056974
stoichiometry: 1.0
species: 040390
type: SpeciesReference

021520
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: _5-Amino-2-oxopentanoate_C5H9NO3
type: Species

042331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Phosphate_HO4P
type: Species

057564
stoichiometry: 1.0
species: 030054
type: SpeciesReference

040849
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: O2_O2
type: Species

136459
stoichiometry: 1.0
species: 030187
type: SpeciesReference

123770
stoichiometry: 3.0
species: 025541
type: SpeciesReference

024913
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: AMP_C10H12N5O7P
type: Species

082044
stoichiometry: 1.0
species: 043127
type: SpeciesReference

110378
stoichiometry: 1.0
species: 043223
type: SpeciesReference

130916
stoichiometry: 1.0
species: 023042
type: SpeciesReference

150415
stoichiometry: 8.0
species: 034253
type: SpeciesReference

108667
stoichiometry: 6.0
species: 040198
type: SpeciesReference

056829
stoichiometry: 1.0
species: 022680
type: SpeciesReference

031568
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Fructose_C6H12O6
type: Species

050299
stoichiometry: 32.0
species: 027218
type: SpeciesReference

056768
stoichiometry: 1.0
species: 044851
type: SpeciesReference

928879
product: 096528
is: http://identifiers.org/ec-code/3.1.2.6
fast: false
product: 096480
product: 096468
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D R_GLYOXm subsystem: Pyruvate Metabolism R_GLYOXm equation: [m] : h2o + lgt-S --> gthrd + h + lac-D
reactant: 096420
product: 096492
reactant: 096444
product: 096516
product: 096504
reactant: 096456
is: ENSMMUG00000000737.2
reactant: 096432
type: Reaction
reversible: false

931201
type: Reaction
is: ENSMMUG00000014682.2
reactant: 120393
is: ENSMMUG00000000694.2
fast: false
is: ENSMMUG00000000985.2
notes: R_PI4PLC subsystem: Inositol Phosphate Metabolism R_PI4PLC equation: [c] : h2o + pail4p_hs --> dag_hs + h + mi14p R_PI45PLC subsystem: Inositol Phosphate Metabolism R_PI45PLC equation: [c] : h2o + pail45p_hs --> dag_hs + h + mi145p R_PIPLC subsystem: Inositol Phosphate Metabolism R_PIPLC equation: [c] : h2o + pail_hs --> dag_hs + h + mi1p-D
is: ENSMMUG00000012948.2
product: 120453
reactant: 120405
is: ENSMMUG00000022175.2
is: ENSMMUG00000005334.2
is: ENSMMUG00000005905.2
reversible: false
product: 120477
is: http://identifiers.org/ec-code/3.1.4.3
reactant: 120429
product: 120465
is: ENSMMUG00000020535.2
is: http://identifiers.org/ec-code/3.1.4.11
product: 120489
is: ENSMMUG00000031170.1
reactant: 120417
is: ENSMMUG00000018341.2
is: ENSMMUG00000009626.2
is: ENSMMUG00000001608.2
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079517
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species: 034857
type: SpeciesReference

092330
stoichiometry: 1.0
species: 029704
type: SpeciesReference

056322
stoichiometry: 2.0
species: 020240
type: SpeciesReference

119510
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species: 035507
type: SpeciesReference

101119
stoichiometry: 1.0
species: 025637
type: SpeciesReference

025721
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Bilirubin beta-diglucuronide_C45H50N4O18
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074879
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species: 046476
type: SpeciesReference

035702
constant: false
boundary condition: false
has only substance units: false
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initial amount: NaN
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932727
is: ENSMMUG00000003585.2
product: 134568
is: http://identifiers.org/ec-code/2.4.1.117
type: Reaction
notes: R_UDPDOLPT_L subsystem: N-Glycan Biosynthesis R_UDPDOLPT_L equation: [c] : (0.1) dolp_L + udpg --> (0.1) dolglcp_L + udp R_UDPDOLPT_U subsystem: N-Glycan Biosynthesis R_UDPDOLPT_U equation: [c] : (0.1) dolp_U + udpg --> (0.1) dolglcp_U + udp
reactant: 134520
product: 134544
product: 134556
reactant: 134507
fast: false
reversible: false
reactant: 134532

148177
stoichiometry: 6.0
species: 040017
type: SpeciesReference

076785
stoichiometry: 1.0
species: 029223
type: SpeciesReference

933051
is: http://identifiers.org/ec-code/1.3.3.4
fast: false
product: 137436
name: protoporphyrinogen oxidase, mitochondrial
product: 137448
notes: R_PPPGOm subsystem: Heme Biosynthesis R_PPPGOm equation: [m] : (3) o2 + (2) pppg9 --> (6) h2o + (2) ppp9
reversible: false
is: ENSMMUG00000022630.2
type: Reaction
reactant: 137424
reactant: 137411

039116
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Maltotriose_C18H32O16
type: Species

084554
stoichiometry: 2.0
species: 028764
type: SpeciesReference

065741
stoichiometry: 1.0
species: 046476
type: SpeciesReference

139402
stoichiometry: 1.0
species: 033263
type: SpeciesReference

137833
stoichiometry: 2.0
species: 034253
type: SpeciesReference

019634
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _17alpha-Hydroxypregnenolone_C21H32O3
type: Species

049622
stoichiometry: 2.0
species: 040306
type: SpeciesReference

094451
stoichiometry: 1.0
species: 034665
type: SpeciesReference

048693
stoichiometry: 2.0
species: 034253
type: SpeciesReference

108727
stoichiometry: 1.0
species: 040270
type: SpeciesReference

096468
stoichiometry: 1.0
species: 037717
type: SpeciesReference

149846
stoichiometry: 1.0
species: 027145
type: SpeciesReference

059714
stoichiometry: 1.0
species: 022644
type: SpeciesReference

035435
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 12_C79H119N5O83S6X
type: Species

059867
stoichiometry: 1.0
species: 021074
type: SpeciesReference

098356
stoichiometry: 1.0
species: 022837
type: SpeciesReference

095403
stoichiometry: 2.0
species: 035689
type: SpeciesReference

931561
product: 123385
product: 123361
type: Reaction
reactant: 123313
product: 123397
reversible: false
reactant: 123337
product: 123409
fast: false
reactant: 123301
is: ENSMMUG00000005442.2
is: http://identifiers.org/ec-code/3.1.3.5
reactant: 123325
notes: R_NTD7e subsystem: Nucleotides R_NTD7e equation: [e] : amp + h2o --> adn + pi R_NTD2e subsystem: Nucleotides R_NTD2e equation: [e] : h2o + ump --> pi + uri R_NTD9e subsystem: Nucleotides R_NTD9e equation: [e] : gmp + h2o --> gsn + pi R_NTD4e subsystem: Nucleotides R_NTD4e equation: [e] : cmp + h2o --> cytd + pi
product: 123373
reactant: 123349

110957
stoichiometry: 1.0
species: 030261
type: SpeciesReference

043596
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: fatty acid retinol_C20H29OFULLR2CO
type: Species

042103
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: phosphatidyl glycerol phosphate (homo sapiens)_C6H11O9P2FULLRCO2FULLR2CO2
type: Species

086896
stoichiometry: 1.0
species: 043945
type: SpeciesReference

028509
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2
type: Species

054905
stoichiometry: 1.0
species: 030746
type: SpeciesReference

925829
reactant: 068452
reactant: 068428
product: 068669
reactant: 068356
product: 068826
fast: false
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reactant: 068416
product: 068766
product: 068597
product: 068718
is: ENSMMUG00000009146.2
product: 068645
product: 068681
product: 068802
reactant: 068536
product: 068572
product: 068730
reactant: 068380
product: 068838
product: 068621
reactant: 068524
reactant: 068512
reactant: 068488
product: 068778
reactant: 068343
reactant: 068440
reactant: 068331
reactant: 068368
is: http://identifiers.org/ec-code/2.4.1.144
product: 068657
reactant: 068548
product: 068814
reactant: 068560
product: 068694
type: Reaction
reactant: 068500
reversible: false
reactant: 068476
reactant: 068392
product: 068742
reactant: 068307
reactant: 068464
product: 068754
product: 068609
product: 068585
product: 068790
product: 068706
product: 068633
reactant: 068404

125218
stoichiometry: 1.0
species: 041525
type: SpeciesReference

121680
stoichiometry: 1.0
species: 022873
type: SpeciesReference

079394
stoichiometry: 1.0
species: 025372
type: SpeciesReference

141993
stoichiometry: 1.0
species: 021642
type: SpeciesReference

035993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: myo-Inositol_C6H12O6
type: Species

128595
stoichiometry: 1.0
species: 039969
type: SpeciesReference

145565
stoichiometry: 1.0
species: 039885
type: SpeciesReference

028824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: dCTP_C9H12N3O13P3
type: Species

019409
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: _10-Formyltetrahydrofolate_C20H21N7O7
type: Species

140750
stoichiometry: 1.0
species: 023308
type: SpeciesReference

077206
stoichiometry: 1.0
species: 041501
type: SpeciesReference

051674
stoichiometry: 3.0
species: 025541
type: SpeciesReference

107365
stoichiometry: 1.0
species: 046452
type: SpeciesReference

031628
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Lea glycolipid_C50H89N2O26FULLRCO
type: Species

102193
stoichiometry: 1.0
species: 023018
type: SpeciesReference

929503
product: 102579
is: ENSMMUG00000008137.2
product: 102543
product: 102615
reactant: 102494
product: 102591
type: Reaction
reactant: 102519
is: ENSMMUG00000012472.2
reactant: 102482
fast: false
reactant: 102507
product: 102567
product: 102603
product: 102555
notes: R_PI3P5K subsystem: Inositol Phosphate Metabolism R_PI3P5K equation: [c] : atp + pail3p_hs --> adp + h + pail35p_hs R_PI34P5K subsystem: Inositol Phosphate Metabolism R_PI34P5K equation: [c] : atp + pail34p_hs --> adp + h + pail345p_hs R_PIK5 subsystem: Inositol Phosphate Metabolism R_PIK5 equation: [c] : atp + pail_hs --> adp + h + pail5p_hs R_PI4P5K subsystem: Glycerophospholipid Metabolism R_PI4P5K equation: [c] : atp + pail4p_hs --> adp + h + pail45p_hs R_PI3P4K subsystem: Inositol Phosphate Metabolism R_PI3P4K equation: [c] : atp + pail3p_hs --> adp + h + pail34p_hs
is: ENSMMUG00000005228.2
reactant: 102531
reversible: false
is: http://identifiers.org/ec-code/2.7.1.68

924304
reactant: 054159
name: b-galactosidase, extracellular
is: http://identifiers.org/ec-code/3.2.1.23
product: 054171
product: 054184
notes: R_LACZe subsystem: Galactose metabolism R_LACZe equation: [e] : h2o + lcts --> gal + glc-D
fast: false
is: ENSMMUG00000012250.2
type: Reaction
reversible: false
reactant: 054146

099959
stoichiometry: 5.0
species: 040077
type: SpeciesReference

040705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: nervonyl coenzyme A_C45H76N7O17P3S
type: Species

124410
stoichiometry: 1.0
species: 034412
type: SpeciesReference

141173
stoichiometry: 1.0
species: 043488
type: SpeciesReference

126074
stoichiometry: 1.0
species: 034303
type: SpeciesReference

923572
reactant: 047633
product: 047694
reactant: 047609
is: ENSMMUG00000000671.2
product: 047645
is: ENSMMUG00000000673.1
product: 047657
reactant: 047621
reactant: 047597
type: Reaction
is: http://identifiers.org/ec-code/3.1.6.13
fast: false
reversible: false
product: 047670
product: 047682
notes: R_S2TASE2ly subsystem: Heparan sulfate degradation R_S2TASE2ly equation: [l] : h2o + hs_deg21 --> h + hs_deg22 + so4 R_S2TASE1ly subsystem: Heparan sulfate degradation R_S2TASE1ly equation: [l] : h2o + hs_deg15 --> h + hs_deg16 + so4 R_S2TASE3ly subsystem: Chondroitin sulfate degradation R_S2TASE3ly equation: [l] : cs_b_deg2 + h2o --> cs_b_deg3 + h + so4

930894
name: alpha-mannosidase, lysosomal
is: http://identifiers.org/ec-code/3.2.1.24
reversible: false
product: 116861
product: 116873
notes: R_A_MANASEly subsystem: N-Glycan Degradation R_A_MANASEly equation: [l] : (2) h2o + m2mn --> (2) man + mn
reactant: 116836
fast: false
type: Reaction
reactant: 116848
is: ENSMMUG00000016863.2

142174
stoichiometry: 1.0
species: 021678
type: SpeciesReference

119669
stoichiometry: 1.0
species: 038236
type: SpeciesReference

083422
stoichiometry: 1.0
species: 042439
type: SpeciesReference

086278
stoichiometry: 1.0
species: 030759
type: SpeciesReference

068295
stoichiometry: 1.0
species: 034363
type: SpeciesReference

058072
stoichiometry: 1.0
species: 032887
type: SpeciesReference

114371
stoichiometry: 7.0
species: 034253
type: SpeciesReference

120080
stoichiometry: 1.0
species: 042415
type: SpeciesReference

104848
stoichiometry: 1.0
species: 047165
type: SpeciesReference

025130
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-Acetylputrescine_C6H15N2O
type: Species

024058
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: ADP_C10H12N5O10P2
type: Species

930083
fast: false
is: ENSMMUG00000005667.2
reactant: 107220
reversible: true
product: 107256
reactant: 107232
is: http://identifiers.org/ec-code/4.2.1.2
reactant: 107208
product: 107268
notes: R_FUM subsystem: Citric Acid Cycle R_FUM equation: [c] : fum + h2o <==> mal-L R_FUMm subsystem: Citric Acid Cycle R_FUMm equation: [m] : fum + h2o <==> mal-L
type: Reaction
reactant: 107244

038718
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1545H2540N20O470P20
type: Species

112454
stoichiometry: 1.0
species: 032584
type: SpeciesReference

148625
stoichiometry: 1.0
species: 025179
type: SpeciesReference

057818
stoichiometry: 1.0
species: 043331
type: SpeciesReference

097515
stoichiometry: 1.0
species: 034436
type: SpeciesReference

044150
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: D-Serine_C3H7NO3
type: Species

023211
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Acetyl-CoA_C23H34N7O17P3S
type: Species

151223
stoichiometry: 8.0
species: 034387
type: SpeciesReference

053591
stoichiometry: 1.0
species: 034363
type: SpeciesReference

039276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Methanol_CH4O1
type: Species

103147
stoichiometry: 1.0
species: 040306
type: SpeciesReference

056177
stoichiometry: 1.0
species: 024646
type: SpeciesReference

143104
stoichiometry: 1.0
species: 037475
type: SpeciesReference

030673
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: elaidic acid_C18H33O2
type: Species

127244
stoichiometry: 1.0
species: 032076
type: SpeciesReference

118582
stoichiometry: 3.0
species: 028800
type: SpeciesReference

088197
stoichiometry: 1.0
species: 027218
type: SpeciesReference

072974
stoichiometry: 1.0
species: 032221
type: SpeciesReference

932618
is: ENSMMUG00000000684.2
reversible: false
is: http://identifiers.org/ec-code/1.3.99.3
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD10m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ACOAD10m equation: [m] : 2mbcoa + fad --> 2mb2coa + fadh2 R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2
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fast: false
is: http://identifiers.org/ec-code/1.3.99.12
product: 133767
product: 133780
product: 133793
product: 133754
reactant: 133729
type: Reaction
is: http://identifiers.org/ec-code/1.3.99.2
reactant: 133716
reactant: 133704

121968
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species: 038959
type: SpeciesReference

143321
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species: 036461
type: SpeciesReference

042560
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Diphosphate_HO7P2
type: Species

084663
stoichiometry: 1.0
species: 020846
type: SpeciesReference

032972
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Glucarate_C6H8O8
type: Species

103037
stoichiometry: 1.0
species: 039969
type: SpeciesReference

076351
stoichiometry: 1.0
species: 033070
type: SpeciesReference

024453
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole_C8H12N3O7P
type: Species

087220
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species: 035423
type: SpeciesReference

141450
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species: 033554
type: SpeciesReference

030467
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dUTP_C9H11N2O14P3
type: Species

108510
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species: 039849
type: SpeciesReference

045237
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: tetracosatetraenoic acid n-6_C24H39O2
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150524
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species: 025637
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122268
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species: 020459
type: SpeciesReference

098200
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species: 020617
type: SpeciesReference

067391
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species: 033579
type: SpeciesReference

148589
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species: 027542
type: SpeciesReference

130807
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species: 040198
type: SpeciesReference

110487
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species: 034327
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129814
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species: 035872
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094343
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species: 027073
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species: 030345
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148021
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species: 022462
type: SpeciesReference

128558
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species: 031532
type: SpeciesReference

042620
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: _5-Diphosphoinositol pentakisphosphate_C6H6O27P7
type: Species

127355
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species: 034363
type: SpeciesReference

039475
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-Methylhistamine_C6H12N3
type: Species

100818
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species: 034253
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137532
stoichiometry: 1.0
species: 027061
type: SpeciesReference

092486
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species: 030686
type: SpeciesReference

025831
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Biocytin_C16H28N4O4S
type: Species

111029
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species: 046683
type: SpeciesReference

151379
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species: 034953
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101264
stoichiometry: 2.0
species: 023066
type: SpeciesReference

062138
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species: 045923
type: SpeciesReference

044404
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: Sphingosine_C18H38NO2
type: Species

038923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2
type: Species

078549
stoichiometry: 1.0
species: 020398
type: SpeciesReference

104090
stoichiometry: 1.0
species: 046719
type: SpeciesReference

137942
stoichiometry: 1.0
species: 030467
type: SpeciesReference

129922
stoichiometry: 1.0
species: 034363
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111173
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species: 041778
type: SpeciesReference

080034
stoichiometry: 1.0
species: 026481
type: SpeciesReference

093414
stoichiometry: 2.0
species: 034387
type: SpeciesReference

078898
stoichiometry: 1.0
species: 034569
type: SpeciesReference

140352
stoichiometry: 1.0
species: 037572
type: SpeciesReference

131291
stoichiometry: 1.0
species: 036788
type: SpeciesReference

142283
stoichiometry: 1.0
species: 022292
type: SpeciesReference

094934
stoichiometry: 1.0
species: 025613
type: SpeciesReference

073226
stoichiometry: 1.0
species: 038501
type: SpeciesReference

051782
stoichiometry: 2.0
species: 027181
type: SpeciesReference

087860
stoichiometry: 3.0
species: 042536
type: SpeciesReference

063514
stoichiometry: 1.0
species: 032028
type: SpeciesReference

076568
stoichiometry: 4.0
species: 034303
type: SpeciesReference

112562
stoichiometry: 1.0
species: 020179
type: SpeciesReference

114659
stoichiometry: 1.0
species: 036473
type: SpeciesReference

141884
stoichiometry: 1.0
species: 042163
type: SpeciesReference

134291
stoichiometry: 1.0
species: 024010
type: SpeciesReference

059424
stoichiometry: 1.0
species: 029692
type: SpeciesReference

140641
stoichiometry: 1.0
species: 032645
type: SpeciesReference

052207
stoichiometry: 1.0
species: 040306
type: SpeciesReference

113139
stoichiometry: 1.0
species: 035932
type: SpeciesReference

031001
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Ethanolamine_C2H8NO
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notes: R_BPNT2 subsystem: Nucleotides R_BPNT2 equation: [c] : h2o + paps --> aps + pi R_BPNT subsystem: Nucleotides R_BPNT equation: [c] : h2o + pap --> amp + pi
product: 048706
reactant: 048693
is: http://identifiers.org/ec-code/3.1.3.7
reversible: false
is: ENSMMUG00000017396.2
type: Reaction
product: 048730
reactant: 048681
fast: false
product: 048718
reactant: 048669

928434
fast: false
is: ENSMMUG00000000130.2
reactant: 093185
reactant: 093149
is: http://identifiers.org/ec-code/2.4.1.175
product: 093306
reactant: 093173
product: 093258
product: 093234
product: 093294
product: 093270
reactant: 093210
reactant: 093198
product: 093246
product: 093282
type: Reaction
is: ENSMMUG00000015405.2
is: http://identifiers.org/ec-code/2.4.1.174
reactant: 093161
reactant: 093222
notes: R_GALNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT1g equation: [g] : cs,hs_linkage + udpacgal --> cs_pre + h + udp R_GALNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT5g equation: [g] : cs_e_pre3 + uacgam --> cs_e_pre4 + h + udp R_GALNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT4g equation: [g] : cs_d_pre3 + uacgam --> cs_d_pre4 + h + udp R_GALNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT3g equation: [g] : cs_c_pre2 + uacgam --> cs_c_pre3 + h + udp R_GALNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT2g equation: [g] : cs_a,b_pre2 + uacgam --> cs_a,b_pre3 + h + udp
reversible: false

081200
stoichiometry: 1.0
species: 034014
type: SpeciesReference

075278
stoichiometry: 4.0
species: 041754
type: SpeciesReference

056430
stoichiometry: 4.0
species: 034253
type: SpeciesReference

023102
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Acetate_C2H3O2
type: Species

102085
stoichiometry: 1.0
species: 027242
type: SpeciesReference

143213
stoichiometry: 1.0
species: 037220
type: SpeciesReference

146516
stoichiometry: 2.0
species: 040270
type: SpeciesReference

065310
stoichiometry: 1.0
species: 036788
type: SpeciesReference

056286
stoichiometry: 1.0
species: 024010
type: SpeciesReference

138482
stoichiometry: 1.0
species: 034363
type: SpeciesReference

038827
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C64H107N2O50X
type: Species

148734
stoichiometry: 2.0
species: 027145
type: SpeciesReference

077316
stoichiometry: 1.0
species: 043428
type: SpeciesReference

086494
stoichiometry: 1.0
species: 038682
type: SpeciesReference

057927
stoichiometry: 1.0
species: 022425
type: SpeciesReference

084963
stoichiometry: 4.0
species: 041030
type: SpeciesReference

073371
stoichiometry: 36.0
species: 034339
type: SpeciesReference

136567
stoichiometry: 1.0
species: 025300
type: SpeciesReference

058494
stoichiometry: 1.0
species: 043536
type: SpeciesReference

021895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Methylthioadenosine_C11H15N5O3S
type: Species

042776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Pregnenolone_C21H32O2
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138772
stoichiometry: 1.0
species: 042824
type: SpeciesReference

020289
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3',5'-Cyclic GMP_C10H11N5O7P
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150270
stoichiometry: 1.0
species: 046199
type: SpeciesReference

131582
stoichiometry: 1.0
species: 037148
type: SpeciesReference

138350
stoichiometry: 2.0
species: 032753
type: SpeciesReference

138627
stoichiometry: 1.0
species: 043644
type: SpeciesReference

060950
stoichiometry: 1.0
species: 040162
type: SpeciesReference

093703
stoichiometry: 1.0
species: 034363
type: SpeciesReference

065476
stoichiometry: 1.0
species: 036908
type: SpeciesReference

124809
stoichiometry: 1.0
species: 043476
type: SpeciesReference

080301
stoichiometry: 4.0
species: 025541
type: SpeciesReference

052845
stoichiometry: 1.0
species: 041621
type: SpeciesReference

071583
stoichiometry: 1.0
species: 024300
type: SpeciesReference

146877
stoichiometry: 5.0
species: 042283
type: SpeciesReference

026239
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Cob(II)alamin_C62H92CoN13O14P
type: Species

087571
stoichiometry: 1.0
species: 028122
type: SpeciesReference

128862
stoichiometry: 1.0
species: 028497
type: SpeciesReference

122521
stoichiometry: 3.0
species: 034253
type: SpeciesReference

063730
stoichiometry: 1.0
species: 040222
type: SpeciesReference

050601
stoichiometry: 22.0
species: 034241
type: SpeciesReference

046319
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
type: Species

030078
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Dopamine_C8H12NO2
type: Species

098728
stoichiometry: 1.0
species: 044609
type: SpeciesReference

094246
stoichiometry: 2.0
species: 034363
type: SpeciesReference

136157
stoichiometry: 1.0
species: 034436
type: SpeciesReference

087787
stoichiometry: 1.0
species: 026554
type: SpeciesReference

119741
stoichiometry: 1.0
species: 024190
type: SpeciesReference

083314
stoichiometry: 1.0
species: 039302
type: SpeciesReference

083037
stoichiometry: 1.0
species: 028279
type: SpeciesReference

139857
stoichiometry: 2.0
species: 023731
type: SpeciesReference

074303
stoichiometry: 2.0
species: 034363
type: SpeciesReference

068886
stoichiometry: 1.0
species: 029346
type: SpeciesReference

135891
stoichiometry: 2.0
species: 038754
type: SpeciesReference

020496
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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type: Species

147695
stoichiometry: 1.0
species: 029102
type: SpeciesReference

926789
type: Reaction
reactant: 076411
is: http://identifiers.org/ec-code/1.1.2.3
product: 076435
notes: R_L_DASH_LACDcm subsystem: Pyruvate Metabolism R_L_DASH_LACDcm equation: (2) ficytC[m] + lac-L[c] --> (2) focytC[m] + (2) h[c] + pyr[c]
product: 076447
is: ENSMMUG00000008179.2
name: L-Lactate dehydrogenase, cytosolic/mitochondrial
product: 076459
reactant: 076423
fast: false
reversible: false

055657
stoichiometry: 1.0
species: 042752
type: SpeciesReference

037766
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Lactaldehyde_C3H6O2
type: Species

024889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: AMP_C10H12N5O7P
type: Species

037693
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Lactate_C3H5O3
type: Species

041693
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: phosphatidylinositol (homo sapiens)_C9H16O9PFULLRCO2FULLR2CO2
type: Species

078003
stoichiometry: 1.0
species: 039499
type: SpeciesReference

046031
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Thiosulfate_O3S2
type: Species

084398
stoichiometry: 1.0
species: 028255
type: SpeciesReference

049852
stoichiometry: 8.0
species: 040017
type: SpeciesReference

097239
stoichiometry: 1.0
species: 021823
type: SpeciesReference

069586
stoichiometry: 1.0
species: 027771
type: SpeciesReference

924748
product: 057878
is: ENSMMUG00000010206.2
reactant: 057854
reactant: 057842
is: ENSMMUG00000023454.2
reactant: 057830
fast: false
notes: R_PYK subsystem: Glycolysis/Gluconeogenesis R_PYK equation: [c] : adp + h + pep --> atp + pyr
reversible: false
product: 057866
name: pyruvate kinase
type: Reaction
is: ENSMMUG00000004145.2
is: http://identifiers.org/ec-code/2.7.1.40
is: ENSMMUG00000014623.2
is: ENSMMUG00000017301.2
is: ENSMMUG00000023143.2

118149
stoichiometry: 1.0
species: 029873
type: SpeciesReference

118076
stoichiometry: 1.0
species: 034436
type: SpeciesReference

928182
product: 088642
modifier: 088823
modifier: 088811
is: ENSMMUG00000017109.1
product: 088654
modifier: 088726
modifier: 088702
modifier: 088678
reversible: false
modifier: 088762
modifier: 088786
type: Reaction
modifier: 088738
modifier: 088714
modifier: 088859
modifier: 088835
modifier: 088774
reactant: 088606
modifier: 088750
modifier: 088871
modifier: 088798
notes: R_PUNP5 subsystem: Purine Catabolism R_PUNP5 equation: [c] : ins + pi <==> hxan + r1p R_PUNP3 subsystem: Purine Catabolism R_PUNP3 equation: [c] : gsn + pi <==> gua + r1p R_PUNP4 subsystem: Purine Catabolism R_PUNP4 equation: [c] : dgsn + pi <==> 2dr1p + gua R_PUNP2 subsystem: Purine Catabolism R_PUNP2 equation: [c] : dad-2 + pi <==> 2dr1p + ade R_PUNP1 subsystem: Nucleotides R_PUNP1 equation: [c] : adn + pi <==> ade + r1p R_PUNP7 subsystem: Nucleotides R_PUNP7 equation: [c] : pi + xtsn <==> r1p + xan R_PUNP6 subsystem: Purine Catabolism R_PUNP6 equation: [c] : din + pi <==> 2dr1p + hxan R_DURIPP subsystem: Nucleotides R_DURIPP equation: [c] : duri + pi <==> 2dr1p + ura R_PNP subsystem: NAD Metabolism R_PNP equation: [c] : pi + rnam <==> h + ncam + r1p R_NP1 subsystem: NAD Metabolism R_NP1 equation: [c] : h + nac + r1p --> nicrns + pi
fast: false
reactant: 088618
modifier: 088847
is: http://identifiers.org/ec-code/2.4.2.1
is: ENSMMUG00000019126.2
modifier: 088666
reactant: 088630
modifier: 088883
modifier: 088690

049925
stoichiometry: 1.0
species: 027942
type: SpeciesReference

055247
stoichiometry: 1.0
species: 020009
type: SpeciesReference

129560
stoichiometry: 1.0
species: 040765
type: SpeciesReference

037329
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 10_C81H130N6O64S2X
type: Species

128185
stoichiometry: 1.0
species: 040270
type: SpeciesReference

089355
stoichiometry: 1.0
species: 037609
type: SpeciesReference

021002
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _4,4-dimethylcholesta-8,14,24-trienol_C29H46O
type: Species

032826
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: GDP-L-fucose_C16H23N5O15P2
type: Species

027614
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 2_C37H55NO38S2
type: Species

125519
stoichiometry: 1.0
species: 019828
type: SpeciesReference

051468
stoichiometry: 1.0
species: 043476
type: SpeciesReference

109610
stoichiometry: 2.0
species: 025589
type: SpeciesReference

136843
stoichiometry: 1.0
species: 042524
type: SpeciesReference

020386
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _3-Decaprenyl-4,5-dihdydroxybenzoate_C57H85O4
type: Species

147251
stoichiometry: 1.0
species: 038923
type: SpeciesReference

027338
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Creatine_C4H9N3O2
type: Species

132220
stoichiometry: 1.0
species: 030066
type: SpeciesReference

077955
stoichiometry: 1.0
species: 042644
type: SpeciesReference

101891
stoichiometry: 3.0
species: 024792
type: SpeciesReference

033046
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Glutamine_C5H10N2O3
type: Species

150958
stoichiometry: 1.0
species: 034290
type: SpeciesReference

074723
stoichiometry: 1.0
species: 034253
type: SpeciesReference

085938
stoichiometry: 1.0
species: 040162
type: SpeciesReference

057673
stoichiometry: 2.0
species: 032100
type: SpeciesReference

096174
stoichiometry: 1.0
species: 039764
type: SpeciesReference

075900
stoichiometry: 1.0
species: 022933
type: SpeciesReference

032270
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO
type: Species

022268
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: heptaglutamyl folate (THF)_C49H57N13O24
type: Species

129067
stoichiometry: 1.0
species: 038742
type: SpeciesReference

116426
stoichiometry: 2.0
species: 020179
type: SpeciesReference

095956
stoichiometry: 1.0
species: 043066
type: SpeciesReference

067789
stoichiometry: 1.0
species: 026506
type: SpeciesReference

145140
stoichiometry: 1.0
species: 037292
type: SpeciesReference

064368
stoichiometry: 1.0
species: 044283
type: SpeciesReference

121752
stoichiometry: 1.0
species: 022957
type: SpeciesReference

113621
stoichiometry: 1.0
species: 034339
type: SpeciesReference

112248
stoichiometry: 1.0
species: 040222
type: SpeciesReference

927629
fast: false
reversible: true
name: ribulose 5-phosphate 3-epimerase
notes: R_RPE subsystem: Pentose Phosphate Pathway R_RPE equation: [c] : ru5p-D <==> xu5p-D
reactant: 084144
is: http://identifiers.org/ec-code/5.1.3.1
type: Reaction
is: ENSMMUG00000007655.2
is: ENSMMUG00000010513.2
product: 084156

093294
stoichiometry: 1.0
species: 028110
type: SpeciesReference

923944
reactant: 051060
name: N-acetylglucosamine-6-phosphate deacetylase
type: Reaction
fast: false
product: 051072
reactant: 051048
reversible: false
is: http://identifiers.org/ec-code/3.5.1.25
is: ENSMMUG00000019095.2
notes: R_AGDC subsystem: Aminosugar Metabolism R_AGDC equation: [c] : acgam6p + h2o --> ac + gam6p
product: 051084

042860
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: pristanal_C19H38O
type: Species

933135
reactant: 137857
is: ENSMMUG00000020132.2
product: 137905
fast: false
notes: R_GCNTg subsystem: Blood Group Biosynthesis R_GCNTg equation: [g] : galacglcgal14acglcgalgluside_hs + uacgam --> acglcgalacglcgal14acglcgalgluside_hs + h + udp
type: Reaction
product: 137893
is: http://identifiers.org/ec-code/2.4.1.150
reversible: false
product: 137881
name: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
reactant: 137869

064910
stoichiometry: 1.0
species: 034869
type: SpeciesReference

081635
stoichiometry: 1.0
species: 034545
type: SpeciesReference

021678
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: pentaglutamyl folate (DHF)_C39H43N11O18
type: Species

047165
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: cholesterol ester (from FULLR2)_C27H45FULLR2CO2
type: Species

036800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 13_C143H231N10O111S3X
type: Species

133197
stoichiometry: 44.0
species: 034363
type: SpeciesReference

073591
stoichiometry: 1.0
species: 029801
type: SpeciesReference

035556
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 7_C73H109N4O58X
type: Species

101674
stoichiometry: 1.0
species: 044533
type: SpeciesReference

042403
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S
type: Species

058506
stoichiometry: 1.0
species: 040102
type: SpeciesReference

047682
stoichiometry: 1.0
species: 035169
type: SpeciesReference

090889
stoichiometry: 1.0
species: 025505
type: SpeciesReference

070020
stoichiometry: 1.0
species: 034351
type: SpeciesReference

094560
stoichiometry: 1.0
species: 030018
type: SpeciesReference

097191
stoichiometry: 1.0
species: 024034
type: SpeciesReference

142066
stoichiometry: 1.0
species: 022003
type: SpeciesReference

081311
stoichiometry: 1.0
species: 045887
type: SpeciesReference

062657
stoichiometry: 3.0
species: 022328
type: SpeciesReference

932835
reactant: 135241
product: 135289
reactant: 135253
product: 135277
reversible: false
type: Reaction
notes: R_CH25H subsystem: Bile Acid Biosynthesis R_CH25H equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol25oh
name: cholesterol 25-hydroxylase
fast: false
product: 135301
reactant: 135229
reactant: 135265
is: ENSMMUG00000013506.2

046887
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: w-hydroxyl arachidonic acid_C20H31O3
type: Species

072538
stoichiometry: 1.0
species: 022123
type: SpeciesReference

091239
stoichiometry: 1.0
species: 037584
type: SpeciesReference

925180
fast: false
is: ENSMMUG00000002321.2
product: 062488
reactant: 062440
reactant: 062452
name: Na+/Ca2+-K+ exchange
product: 062464
reactant: 062427
reversible: true
is: ENSMMUG00000013960.2
type: Reaction
notes: R_NCKt subsystem: Transport, Extracellular R_NCKt equation: ca2[e] + k[e] + (4) na1[c] <==> ca2[c] + k[c] + (4) na1[e]
product: 062476

125652
stoichiometry: 3.0
species: 034363
type: SpeciesReference

933351
reversible: false
reactant: 139194
product: 139206
product: 139254
type: Reaction
reactant: 139158
product: 139218
is: ENSMMUG00000012700.2
product: 139242
reactant: 139170
fast: false
product: 139230
reactant: 139182
notes: R_H2MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H2MTer_U equation: [r] : (0.1) dolmanp_U + mgacpail_hs --> (0.1) dolp_U + h + m2gacpail_hs R_H5MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H5MTer_U equation: [r] : (0.1) dolmanp_U + emgacpail_hs --> (0.1) dolp_U + h + memgacpail_hs R_H2MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H2MTer_L equation: [r] : (0.1) dolmanp_L + mgacpail_hs --> (0.1) dolp_L + h + m2gacpail_hs R_H5MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H5MTer_L equation: [r] : (0.1) dolmanp_L + emgacpail_hs --> (0.1) dolp_L + h + memgacpail_hs

924676
type: Reaction
is: ENSMMUG00000004209.2
notes: R_SFGTH subsystem: Tyrosine metabolism R_SFGTH equation: [c] : Sfglutth + h2o <==> for + gthrd + h
product: 057419
reactant: 057395
reactant: 057383
name: S-Formylglutathione hydralase
product: 057407
product: 057431
reversible: true
fast: false
is: http://identifiers.org/ec-code/3.1.2.12

104247
stoichiometry: 1.0
species: 040162
type: SpeciesReference

928722
product: 095463
reversible: false
product: 095511
is: http://identifiers.org/ec-code/1.11.1.8
product: 095451
reactant: 095379
type: Reaction
is: ENSMMUG00000009662.2
reactant: 095343
reactant: 095355
reactant: 095391
reactant: 095403
reactant: 095367
notes: R_IDHPOXOXb subsystem: Tyrosine metabolism R_IDHPOXOXb equation: [c] : iodine + tyr-L --> 3ityr-L + h + i R_IDHPOXOX2b subsystem: Tyrosine metabolism R_IDHPOXOX2b equation: [c] : 3ityr-L + iodine --> 35diotyr + h + i R_IDHPOXOX3 subsystem: Tyrosine metabolism R_IDHPOXOX3 equation: [c] : 35diotyr + 3ityr-L + h2o2 --> 2amac + (2) h2o + triodthy R_IDHPOXOX4 subsystem: Tyrosine metabolism R_IDHPOXOX4 equation: [c] : (2) 35diotyr + h2o2 --> 2amac + (2) h2o + thyox-L R_THYPX subsystem: Tyrosine metabolism R_THYPX equation: [c] : (2) h + h2o2 + (2) i --> (2) h2o + iodine
product: 095499
product: 095439
reactant: 095415
fast: false
product: 095475
product: 095487
product: 095523
product: 095427

030249
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dTMP_C10H13N2O8P
type: Species

147611
stoichiometry: 1.0
species: 044520
type: SpeciesReference

070321
stoichiometry: 1.0
species: 039390
type: SpeciesReference

085782
stoichiometry: 2.0
species: 019767
type: SpeciesReference

070755
stoichiometry: 1.0
species: 045705
type: SpeciesReference

025553
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: ATP_C10H12N5O13P3
type: Species

062584
stoichiometry: 1.0
species: 027073
type: SpeciesReference

050082
stoichiometry: 1.0
species: 027954
type: SpeciesReference

088943
stoichiometry: 1.0
species: 023235
type: SpeciesReference

054389
stoichiometry: 18.0
species: 040017
type: SpeciesReference

151030
stoichiometry: 1.0
species: 027386
type: SpeciesReference

105752
stoichiometry: 1.0
species: 024034
type: SpeciesReference

122207
stoichiometry: 1.0
species: 032560
type: SpeciesReference

107064
stoichiometry: 1.0
species: 041465
type: SpeciesReference

130662
stoichiometry: 1.0
species: 023066
type: SpeciesReference

060301
stoichiometry: 2.0
species: 026808
type: SpeciesReference

087002
stoichiometry: 1.0
species: 035181
type: SpeciesReference

095511
stoichiometry: 6.0
species: 034253
type: SpeciesReference

927353
product: 081551
reactant: 081515
notes: R_ADPGLC subsystem: Nucleotides R_ADPGLC equation: [c] : adpglc + h2o --> amp + g1p + (2) h R_ADPMAN subsystem: Nucleotides R_ADPMAN equation: [c] : adpman + h2o --> amp + (2) h + man1p R_ADPRDP subsystem: Nucleotides R_ADPRDP equation: [c] : adprib + h2o --> amp + (2) h + r5p
reactant: 081527
product: 081599
product: 081575
reversible: false
fast: false
is: ENSMMUG00000017141.2
type: Reaction
is: http://identifiers.org/ec-code/3.6.1.13
reactant: 081539
product: 081587
product: 081563
is: http://identifiers.org/ec-code/3.6.1.21
reactant: 081503

026083
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
type: Species

128716
stoichiometry: 1.0
species: 026384
type: SpeciesReference

052628
stoichiometry: 1.0
species: 034363
type: SpeciesReference

058349
stoichiometry: 1.0
species: 024010
type: SpeciesReference

059013
stoichiometry: 1.0
species: 038405
type: SpeciesReference

028716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: dCMP_C9H12N3O7P
type: Species

135217
stoichiometry: 1.0
species: 032172
type: SpeciesReference

929251
notes: R_3DSPHR subsystem: Sphingolipid Metabolism R_3DSPHR equation: [c] : 3dsphgn + h + nadph --> nadp + sphgn
reactant: 100626
is: http://identifiers.org/ec-code/1.1.1.102
fast: false
type: Reaction
name: _3-Dehydrosphinganine reductase
reactant: 100650
is: ENSMMUG00000006578.2
reactant: 100638
product: 100674
product: 100662
reversible: false

061826
stoichiometry: 1.0
species: 044283
type: SpeciesReference

075496
stoichiometry: 1.0
species: 026566
type: SpeciesReference

088088
stoichiometry: 1.0
species: 044174
type: SpeciesReference

065885
stoichiometry: 1.0
species: 030078
type: SpeciesReference

078441
stoichiometry: 1.0
species: 025541
type: SpeciesReference

106632
stoichiometry: 3.0
species: 036173
type: SpeciesReference

926573
product: 074675
reactant: 074663
notes: R_GLCAE2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAE2g equation: [g] : hs_pre10 --> hs_pre11
is: ENSMMUG00000021364.2
is: http://identifiers.org/ec-code/5.1.3.17
fast: false
reversible: false
name: heparosan-N-sulfate-glucuronate 5-epimerase
type: Reaction

062030
stoichiometry: 1.0
species: 040162
type: SpeciesReference

078184
stoichiometry: 1.0
species: 046067
type: SpeciesReference

097047
stoichiometry: 1.0
species: 025541
type: SpeciesReference

022945
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Tn antigen_C8H14NO5X
type: Species

138905
stoichiometry: 1.0
species: 019634
type: SpeciesReference

062246
stoichiometry: 1.0
species: 032234
type: SpeciesReference

143429
stoichiometry: 1.0
species: 037232
type: SpeciesReference

934432
reactant: 151331
type: Reaction
product: 151343
reversible: true
is: http://identifiers.org/ec-code/4.3.2.1
name: argininosuccinate lyase
product: 151355
is: ENSMMUG00000013434.2
notes: R_ARGSL subsystem: Alanine and Aspartate Metabolism R_ARGSL equation: [c] : argsuc <==> arg-L + fum
fast: false

133905
stoichiometry: 1.0
species: 036005
type: SpeciesReference

929686
is: ENSMMUG00000004624.2
product: 103801
type: Reaction
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_MI145PP subsystem: Inositol Phosphate Metabolism R_MI145PP equation: [c] : h2o + mi145p --> mi14p + pi R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi R_MI1345PP subsystem: Inositol Phosphate Metabolism R_MI1345PP equation: [c] : h2o + mi1345p --> mi134p + pi
product: 103789
is: ENSMMUG00000003105.2
product: 103813
product: 103825
reversible: false
is: ENSMMUG00000023277.2
reactant: 103765
is: http://identifiers.org/ec-code/3.1.3.36
is: http://identifiers.org/ec-code/3.1.3.56
product: 103837
reactant: 103777
reactant: 103741
reactant: 103729
fast: false
is: ENSMMUG00000019334.1
reactant: 103753

118774
stoichiometry: 3.0
species: 029030
type: SpeciesReference

052363
stoichiometry: 3.0
species: 034436
type: SpeciesReference

034749
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)_C27H49N2O8PRS
type: Species

082492
stoichiometry: 1.0
species: 028255
type: SpeciesReference

073444
stoichiometry: 35.0
species: 027218
type: SpeciesReference

031460
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Formate_CH1O2
type: Species

133806
stoichiometry: 1.0
species: 034496
type: SpeciesReference

090286
stoichiometry: 3.0
species: 031145
type: SpeciesReference

124700
stoichiometry: 1.0
species: 039619
type: SpeciesReference

051108
stoichiometry: 6.0
species: 027181
type: SpeciesReference

111861
stoichiometry: 9.0
species: 034303
type: SpeciesReference

028932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Dodecanoyl-CoA (n-C12:0CoA)_C33H54N7O17P3S
type: Species

081851
stoichiometry: 1.0
species: 034290
type: SpeciesReference

037548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II boisynthesis, precursor 2_C47H76N4O33X
type: Species

043933
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Saccharopine_C11H19N2O6
type: Species

923728
reactant: 049104
product: 049128
type: Reaction
reactant: 049080
product: 049177
fast: false
notes: R_PLA2_2 subsystem: Glycerophospholipid Metabolism R_PLA2_2 equation: [c] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs R_PLA2_2e subsystem: Glycerophospholipid Metabolism R_PLA2_2e equation: [e] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
reversible: false
is: ENSMMUG00000021862.2
reactant: 049092
product: 049164
reactant: 049068
is: http://identifiers.org/ec-code/3.1.1.4
product: 049140
product: 049116
product: 049152

928026
is: ENSMMUG00000022144.1
reactant: 087377
reversible: false
type: Reaction
product: 087437
reactant: 087353
product: 087449
product: 087413
reactant: 087389
product: 087425
fast: false
reactant: 087401
reactant: 087365
notes: R_25VITD3Hm subsystem: Vitamin D R_25VITD3Hm equation: [m] : 25hvitd3 + h + nadph + o2 --> 1a25dhvitd3 + h2o + nadp R_25VITD2Hm subsystem: Vitamin D R_25VITD2Hm equation: [m] : 25hvitd2 + h + nadph + o2 --> 1a25dhvitd2 + h2o + nadp

926357
fast: false
reversible: false
product: 072489
product: 072465
name: Squalene epoxidase, endoplasmic reticular (NADP)
type: Reaction
reactant: 072429
product: 072477
is: ENSMMUG00000003535.2
reactant: 072417
is: http://identifiers.org/ec-code/1.14.99.7
reactant: 072441
notes: R_SQLEr subsystem: Cholesterol Metabolism R_SQLEr equation: [r] : h + nadph + o2 + sql --> Ssq23epx + h2o + nadp
reactant: 072453

034179
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Hydrogen peroxide_H2O2
type: Species

034436
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: H+_H
type: Species

073773
stoichiometry: 3.0
species: 041030
type: SpeciesReference

110607
stoichiometry: 1.0
species: 042127
type: SpeciesReference

023394
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: N-Acetyl-D-galactosamine_C8H15NO6
type: Species

105259
stoichiometry: 1.0
species: 042307
type: SpeciesReference

099090
stoichiometry: 1.0
species: 027073
type: SpeciesReference

061058
stoichiometry: 1.0
species: 025251
type: SpeciesReference

047815
stoichiometry: 1.0
species: 037766
type: SpeciesReference

079565
stoichiometry: 1.0
species: 037874
type: SpeciesReference

116982
stoichiometry: 1.0
species: 026131
type: SpeciesReference

091812
stoichiometry: 1.0
species: 034424
type: SpeciesReference

053146
stoichiometry: 1.0
species: 034387
type: SpeciesReference

934204
reactant: 149434
product: 149554
reactant: 149542
reactant: 149458
is: http://identifiers.org/ec-code/6.3.4.15
reactant: 149482
reversible: false
reactant: 149506
product: 149651
reactant: 149470
product: 149602
reactant: 149530
reactant: 149446
product: 149664
notes: R_BACCL subsystem: Biotin Metabolism R_BACCL equation: [c] : atp + btn + h --> btamp + ppi R_BTNPLm subsystem: Biotin Metabolism R_BTNPLm equation: [m] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BTNPL subsystem: Biotin Metabolism R_BTNPL equation: [c] : apoC-Lys + btamp --> amp + apoC-Lys_btn + h R_BACCLm subsystem: Biotin Metabolism R_BACCLm equation: [m] : atp + btn + h --> btamp + ppi
reactant: 149494
fast: false
product: 149627
product: 149615
product: 149590
product: 149566
reactant: 149518
is: ENSMMUG00000015566.2
product: 149639
product: 149578
type: Reaction

143657
stoichiometry: 1.0
species: 035993
type: SpeciesReference

101542
stoichiometry: 1.0
species: 024792
type: SpeciesReference

027554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: chondroitin sulfate/heparan sulfate linkage region (GlcA-(Gal)2-Xyl-L-Ser (protein))_C23H36O20X
type: Species

923872
product: 050516
is: ENSMMUG00000014172.2
product: 050552
reactant: 050191
reactant: 050203
product: 050480
is: http://identifiers.org/ec-code/1.3.99.3
reactant: 050372
product: 050528
reactant: 050275
product: 050589
reactant: 050347
product: 050564
product: 050576
product: 050492
reactant: 050227
product: 050396
product: 050504
reactant: 050167
reactant: 050311
product: 050468
reversible: false
reactant: 050263
product: 050420
reactant: 050335
reactant: 050215
reactant: 050299
fast: false
product: 050432
is: http://identifiers.org/ec-code/1.3.3.6
reactant: 050384
reactant: 050287
product: 050601
product: 050444
type: Reaction
reactant: 050359
product: 050408
reactant: 050239
reactant: 050154
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_FAOXC2051843x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2051843x equation: [x] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_FAOXC16080x subsystem: Fatty acid oxidation, peroxisome R_FAOXC16080x equation: [x] : (4) coa + (4) h2o + (4) nad + (4) o2 + pmtcoa --> (4) accoa + (4) h + (4) h2o2 + (4) nadh + occoa R_FAOXC2242046x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2242046x equation: [x] : adrncoa + coa + h2o + nad + o2 --> accoa + arachdcoa + h + h2o2 + nadh R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_ACOAO7p subsystem: Fatty Acid Metabolism R_ACOAO7p equation: [x] : o2 + pmtcoa --> h2o2 + hdd2coa R_FAOXC18480x subsystem: Fatty acid …
product: 050540
reactant: 050179
reactant: 050251
product: 050613
product: 050456
reactant: 050323

079818
stoichiometry: 1.0
species: 031253
type: SpeciesReference

135096
stoichiometry: 1.0
species: 046659
type: SpeciesReference

026396
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N,N'-Diacetylchitobiosyldiphosphodolichol, human liver homolog_C1240H2028N20O170P20
type: Species

036932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 23_C185H296N13O153S7X
type: Species

070610
stoichiometry: 1.0
species: 037705
type: SpeciesReference

088606
stoichiometry: 1.0
species: 043560
type: SpeciesReference

083735
stoichiometry: 1.0
species: 046271
type: SpeciesReference

103729
stoichiometry: 1.0
species: 041501
type: SpeciesReference

094029
stoichiometry: 1.0
species: 031265
type: SpeciesReference

082092
stoichiometry: 1.0
species: 027073
type: SpeciesReference

928590
product: 094620
reactant: 094560
product: 094608
product: 094632
reactant: 094584
reactant: 094572
is: ENSMMUG00000003774.2
is: ENSMMUG00000009930.1
notes: R_GPIMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIMTer_L equation: [r] : (0.1) dolmanp_L + gacpail_hs --> (0.1) dolp_L + h + mgacpail_hs R_GPIMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIMTer_U equation: [r] : (0.1) dolmanp_U + gacpail_hs --> (0.1) dolp_U + h + mgacpail_hs
reversible: false
fast: false
product: 094596
type: Reaction

125930
stoichiometry: 2.0
species: 040909
type: SpeciesReference

095739
stoichiometry: 2.0
species: 041295
type: SpeciesReference

097623
stoichiometry: 1.0
species: 034387
type: SpeciesReference

104511
stoichiometry: 2.0
species: 034265
type: SpeciesReference

924964
product: 060337
is: ENSMMUG00000014027.2
fast: false
product: 060301
reactant: 060227
reactant: 060240
reactant: 060252
reversible: false
product: 060325
type: Reaction
is: ENSMMUG00000010083.2
reactant: 060265
product: 060289
product: 060349
product: 060313
is: http://identifiers.org/ec-code/1.14.13.39
notes: R_NOS2 subsystem: Arginine and Proline Metabolism R_NOS2 equation: [c] : nadph + (2) nwharg + (2) o2 --> (2) citr-L + h + (2) h2o + nadp + (2) no R_NOS1 subsystem: Arginine and Proline Metabolism R_NOS1 equation: [c] : arg-L + h + nadph + o2 --> h2o + nadp + nwharg
reactant: 060277
is: ENSMMUG00000020437.2

060625
stoichiometry: 1.0
species: 032911
type: SpeciesReference

104957
stoichiometry: 1.0
species: 031846
type: SpeciesReference

092198
stoichiometry: 1.0
species: 022800
type: SpeciesReference

120585
stoichiometry: 1.0
species: 034253
type: SpeciesReference

093076
stoichiometry: 6.0
species: 028473
type: SpeciesReference

066546
stoichiometry: 2.0
species: 024034
type: SpeciesReference

072065
stoichiometry: 1.0
species: 042175
type: SpeciesReference

068452
stoichiometry: 1.0
species: 019265
type: SpeciesReference

929819
product: 104800
is: ENSMMUG00000031126.1
is: ENSMMUG00000017557.1
notes: R_GLCATg subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCATg equation: [g] : l2xser + udpglcur --> cs,hs_linkage + h + udp
product: 104776
reactant: 104764
name: UDP-D-glucuronate:galactosylgalactosylxylose glucuronosyltransferase, Golgi apparatus
reversible: false
product: 104788
reactant: 104752
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.135
fast: false
is: ENSMMUG00000002250.2

147359
stoichiometry: 1.0
species: 039250
type: SpeciesReference

053435
stoichiometry: 1.0
species: 040150
type: SpeciesReference

116836
stoichiometry: 2.0
species: 034290
type: SpeciesReference

114214
stoichiometry: 1.0
species: 037378
type: SpeciesReference

124132
stoichiometry: 1.0
species: 026518
type: SpeciesReference

039691
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: myo-Inositol hexakisphosphate_C6H6O24P6
type: Species

138026
stoichiometry: 1.0
species: 034412
type: SpeciesReference

127692
stoichiometry: 9.0
species: 040077
type: SpeciesReference

129224
stoichiometry: 2.0
species: 045465
type: SpeciesReference

127575
stoichiometry: 1.0
species: 026542
type: SpeciesReference

139629
stoichiometry: 1.0
species: 039250
type: SpeciesReference

926897
reversible: false
type: Reaction
is: ENSMMUG00000000337.2
name: UDP-glucuronosyltransferase 1-10 precursor, microsomal
reactant: 076977
product: 077013
fast: false
product: 077001
reactant: 076989
notes: R_UGT1A3r subsystem: Steroid Metabolism R_UGT1A3r equation: [r] : andrstrn + udpglcur --> andrstrnglc + udp
is: http://identifiers.org/ec-code/2.4.1.17
is: ENSMMUG00000023715.2

097791
stoichiometry: 1.0
species: 021533
type: SpeciesReference

092895
stoichiometry: 6.0
species: 030357
type: SpeciesReference

027013
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: CMP-N-acetylneuraminate_C20H29N4O16P
type: Species

113404
stoichiometry: 1.0
species: 034253
type: SpeciesReference

112029
stoichiometry: 2.0
species: 046199
type: SpeciesReference

033906
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GT1aalpha (homo sapiens)_C77H127N5O46FULLRCO
type: Species

111583
stoichiometry: 1.0
species: 023418
type: SpeciesReference

046464
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: UDP-D-xylose_C14H20N2O16P2
type: Species

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notes: R_HMGCOASim subsystem: Cholesterol Metabolism R_HMGCOASim equation: [m] : aacoa + accoa + h2o --> coa + h + hmgcoa
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product: 086036
is: ENSMMUG00000006948.1
product: 086048
reactant: 085987
reactant: 085999
product: 086023
reversible: false
reactant: 086011
is: http://identifiers.org/ec-code/4.1.3.5
is: ENSMMUG00000023097.2
type: Reaction
name: Hydroxymethylglutaryl CoA synthase (ir)

036041
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: Inosine_C10H12N4O5
type: Species

077737
stoichiometry: 10.0
species: 025541
type: SpeciesReference

082625
stoichiometry: 1.0
species: 020107
type: SpeciesReference

118294
stoichiometry: 1.0
species: 040162
type: SpeciesReference

132956
stoichiometry: 1.0
species: 036185
type: SpeciesReference

033371
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Glycerol 3-phosphate_C3H7O6P
type: Species

091668
stoichiometry: 1.0
species: 034253
type: SpeciesReference

103572
stoichiometry: 4.0
species: 034253
type: SpeciesReference

123037
stoichiometry: 1.0
species: 040198
type: SpeciesReference

122629
stoichiometry: 1.0
species: 039571
type: SpeciesReference

041477
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2
type: Species

072367
stoichiometry: 1.0
species: 024549
type: SpeciesReference

049707
stoichiometry: 1.0
species: 030551
type: SpeciesReference

032124
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Glucose 6-phosphate_C6H11O9P
type: Species

137254
stoichiometry: 1.0
species: 025541
type: SpeciesReference

041187
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S
type: Species

055875
stoichiometry: 1.0
species: 034869
type: SpeciesReference

045645
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: Thymidine_C10H14N2O5
type: Species

930446
reactant: 111125
is: http://identifiers.org/ec-code/2.1.1.5
is: ENSMMUG00000009897.2
type: Reaction
reactant: 111113
product: 111137
notes: R_BHMT subsystem: Glycine, Serine, and Threonine Metabolism R_BHMT equation: [c] : glyb + hcys-L --> dmgly + met-L
fast: false
product: 111149
is: ENSMMUG00000006796.1
reversible: false
name: betaine-homocysteine S-methyltransferase

929963
reversible: true
reactant: 105969
type: Reaction
is: ENSMMUG00000001529.2
product: 106005
fast: false
reactant: 105981
product: 105993
notes: R_AMETt2m subsystem: Transport, Mitochondrial R_AMETt2m equation: ahcys[m] + amet[c] <==> ahcys[c] + amet[m]
name: S-Adenosyl-L-methionine reversible transport, mitochondrial

109393
stoichiometry: 1.0
species: 042283
type: SpeciesReference

082781
stoichiometry: 1.0
species: 035702
type: SpeciesReference

029066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dGMP_C10H12N5O7P
type: Species

060517
stoichiometry: 1.0
species: 040126
type: SpeciesReference

047706
stoichiometry: 1.0
species: 043428
type: SpeciesReference

147828
stoichiometry: 1.0
species: 046659
type: SpeciesReference

078996
stoichiometry: 1.0
species: 027145
type: SpeciesReference

065055
stoichiometry: 1.0
species: 044162
type: SpeciesReference

055464
stoichiometry: 1.0
species: 029411
type: SpeciesReference

104403
stoichiometry: 1.0
species: 044911
type: SpeciesReference

033481
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: glycogen, structure 1 (glycogenin-11[1,4-Glc])_C66H111O56X
type: Species

044887
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Taurine_C2H7NO3S
type: Species

027230
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: cocaine_C17H21NO4
type: Species

036197
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: potassium_K
type: Species

069947
stoichiometry: 1.0
species: 024537
type: SpeciesReference

148481
stoichiometry: 1.0
species: 025251
type: SpeciesReference

096016
stoichiometry: 1.0
species: 034363
type: SpeciesReference

092787
stoichiometry: 6.0
species: 030199
type: SpeciesReference

143549
stoichiometry: 1.0
species: 045681
type: SpeciesReference

141028
stoichiometry: 1.0
species: 025915
type: SpeciesReference

117390
stoichiometry: 1.0
species: 023805
type: SpeciesReference

139737
stoichiometry: 1.0
species: 034545
type: SpeciesReference

132533
stoichiometry: 1.0
species: 037705
type: SpeciesReference

053038
stoichiometry: 3.0
species: 034363
type: SpeciesReference

079673
stoichiometry: 3.0
species: 040270
type: SpeciesReference

034327
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: H2O_H2O
type: Species

069731
stoichiometry: 2.0
species: 040789
type: SpeciesReference

031992
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1840H3028N20O670P20
type: Species

095848
stoichiometry: 1.0
species: 044827
type: SpeciesReference

054086
stoichiometry: 1.0
species: 030710
type: SpeciesReference

043716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Retinoate_C20H27O2
type: Species

046187
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
type: Species

926249
product: 071789
fast: false
reversible: true
reactant: 071741
product: 071777
notes: R_SUCCt4_3 subsystem: Transport, Extracellular R_SUCCt4_3 equation: (3) na1[e] + succ[e] <==> (3) na1[c] + succ[c] R_AKGt4_3 subsystem: Transport, Extracellular R_AKGt4_3 equation: akg[e] + (3) na1[e] <==> akg[c] + (3) na1[c]
type: Reaction
is: ENSMMUG00000016924.2
reactant: 071729
reactant: 071753
product: 071765

929143
fast: false
is: ENSMMUG00000008857.2
product: 099343
reactant: 099331
is: http://identifiers.org/ec-code/3.2.1.14
product: 099356
notes: R_CHTNASEe subsystem: Aminosugar Metabolism R_CHTNASEe equation: [e] : chtn + (2) h2o --> (3) acgam R_CHTNASE subsystem: Aminosugar Metabolism R_CHTNASE equation: [c] : chtn + (2) h2o --> (3) acgam
is: ENSMMUG00000002454.1
reactant: 099319
reversible: false
type: Reaction
reactant: 099295
reactant: 099307

933592
product: 141860
product: 141848
product: 141872
reactant: 141824
notes: R_BDG2HCGHD subsystem: Stilbene, coumarine and lignin biosynthesis R_BDG2HCGHD equation: [c] : bdg2hc + h2o --> 2coum + glc-D + h
fast: false
is: ENSMMUG00000005569.2
reversible: false
is: http://identifiers.org/ec-code/3.2.1.21
type: Reaction
reactant: 141836
name: beta-D-Glucosyl-2-coumarinate glucohydrolase

058047
stoichiometry: 13.0
species: 034253
type: SpeciesReference

133004
stoichiometry: 1.0
species: 036173
type: SpeciesReference

036257
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 13_C174H280N12O150S8
type: Species

117908
stoichiometry: 1.0
species: 025541
type: SpeciesReference

041247
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: hydroxide ion_HO
type: Species

059169
stoichiometry: 1.0
species: 044705
type: SpeciesReference

040994
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO
type: Species

096396
stoichiometry: 1.0
species: 028872
type: SpeciesReference

072259
stoichiometry: 1.0
species: 026844
type: SpeciesReference

061406
stoichiometry: 1.0
species: 043476
type: SpeciesReference

098428
stoichiometry: 1.0
species: 023841
type: SpeciesReference

140074
stoichiometry: 1.0
species: 036932
type: SpeciesReference

029486
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Dihydrolipolprotein_H2S2X
type: Species

100710
stoichiometry: 4.0
species: 034412
type: SpeciesReference

067921
stoichiometry: 1.0
species: 043452
type: SpeciesReference

068343
stoichiometry: 1.0
species: 022232
type: SpeciesReference

134796
stoichiometry: 1.0
species: 034140
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _4-Methyl-2-oxopentanoate_C6H9O3
type: Species

131702
stoichiometry: 1.0
species: 032282
type: SpeciesReference

027446
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Carnitine_C7H15NO3
type: Species

027121
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: CO2_CO2
type: Species

079926
stoichiometry: 1.0
species: 040126
type: SpeciesReference

037970
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Leukotriene C4_C30H45N3O9S
type: Species

091920
stoichiometry: 1.0
species: 040705
type: SpeciesReference

129116
stoichiometry: 13.0
species: 039176
type: SpeciesReference

052060
stoichiometry: 1.0
species: 030941
type: SpeciesReference

087413
stoichiometry: 2.0
species: 034303
type: SpeciesReference

131146
stoichiometry: 1.0
species: 046549
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S
type: Species

128438
stoichiometry: 1.0
species: 032052
type: SpeciesReference

105103
stoichiometry: 2.0
species: 034217
type: SpeciesReference

138134
stoichiometry: 1.0
species: 024598
type: SpeciesReference

042115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Phenylalanine_C9H11NO2
type: Species

041585
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2
type: Species

019217
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

151763
stoichiometry: 1.0
species: 022486
type: SpeciesReference

111751
stoichiometry: 1.0
species: 047057
type: SpeciesReference

045537
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Thiamin triphosphate_C12H16N4O10P3S
type: Species

111474
stoichiometry: 2.0
species: 031592
type: SpeciesReference

104138
stoichiometry: 1.0
species: 020870
type: SpeciesReference

051890
stoichiometry: 1.0
species: 031351
type: SpeciesReference

130552
stoichiometry: 2.0
species: 034315
type: SpeciesReference

125375
stoichiometry: 2.0
species: 024646
type: SpeciesReference

078295
stoichiometry: 4.0
species: 046199
type: SpeciesReference

060457
stoichiometry: 1.0
species: 023138
type: SpeciesReference

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stoichiometry: 2.0
species: 033749
type: SpeciesReference

106848
stoichiometry: 1.0
species: 020774
type: SpeciesReference

058614
stoichiometry: 1.0
species: 024010
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 36_C247H394N17O210S11X
type: Species

127464
stoichiometry: 1.0
species: 031181
type: SpeciesReference

051240
stoichiometry: 1.0
species: 044247
type: SpeciesReference

115019
stoichiometry: 1.0
species: 032947
type: SpeciesReference

034857
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Histidine_C6H9N3O2
type: Species

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stoichiometry: 1.0
species: 040017
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N1-(5-Phospho-D-ribosyl)glycinamide_C7H14N2O8P
type: Species

046779
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: vaccenyl coenzyme A_C39H64N7O17P3S
type: Species

112670
stoichiometry: 1.0
species: 037693
type: SpeciesReference

101783
stoichiometry: 1.0
species: 026650
type: SpeciesReference

077809
stoichiometry: 3.0
species: 024263
type: SpeciesReference

133088
stoichiometry: 1.0
species: 034412
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 10_C55H80N3O70S8
type: Species

047573
stoichiometry: 1.0
species: 034363
type: SpeciesReference

026662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Cholesterol_C27H46O
type: Species

091776
stoichiometry: 1.0
species: 028521
type: SpeciesReference

019561
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _13-cis-retinoate_C20H27O2
type: Species

048548
stoichiometry: 1.0
species: 029018
type: SpeciesReference

134399
stoichiometry: 1.0
species: 037910
type: SpeciesReference

098140
stoichiometry: 1.0
species: 045935
type: SpeciesReference

035665
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Hexadecanal_C16H32O
type: Species

085890
stoichiometry: 1.0
species: 032124
type: SpeciesReference

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product: 087026
reactant: 086935
type: Reaction
is: http://identifiers.org/ec-code/3.2.1.76
reactant: 086961
reactant: 086922
fast: false
reversible: false
reactant: 086974
product: 087014
notes: R_IDOAASE3ly subsystem: Heparan sulfate degradation R_IDOAASE3ly equation: [l] : h2o + hs_deg22 --> hs_deg23 + idour R_IDOAASE2ly subsystem: Heparan sulfate degradation R_IDOAASE2ly equation: [l] : h2o + hs_deg16 --> hs_deg17 + idour R_IDOAASE4ly subsystem: Chondroitin sulfate degradation R_IDOAASE4ly equation: [l] : cs_b_deg3 + h2o --> cs_a_deg3 + idour R_IDOAASE1ly subsystem: Heparan sulfate degradation R_IDOAASE1ly equation: [l] : h2o + hs_deg4 --> hs_deg5 + idour
product: 087002
product: 086988
reactant: 086948
is: ENSMMUG00000032299.1
product: 087038

035217
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 1_C79H115N5O99S11
type: Species

150379
stoichiometry: 1.0
species: 040584
type: SpeciesReference

046611
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Urocanate_C6H5N2O2
type: Species

072646
stoichiometry: 1.0
species: 034253
type: SpeciesReference

924520
type: Reaction
reactant: 056334
reactant: 056322
product: 056418
notes: R_T4HCINNOX subsystem: Stilbene, coumarine and lignin biosynthesis R_T4HCINNOX equation: [c] : (2) T4hcinnm + o2 --> (2) 34dhcinm R_TYRDOPO3 subsystem: Tyrosine metabolism R_TYRDOPO3 equation: [c] : (2) 34dhphe + o2 --> (2) dopaqn + (2) h2o R_TYRDOPO subsystem: Tyrosine metabolism R_TYRDOPO equation: [c] : o2 + (2) tyr-L --> (2) 34dhphe R_DOPACHRMISO subsystem: Tyrosine metabolism R_DOPACHRMISO equation: [c] : (2) 2c23dh56dhoxin + o2 --> (2) L-dpchrm + (2) h2o
is: ENSMMUG00000011115.2
reactant: 056370
product: 056406
is: http://identifiers.org/ec-code/1.14.18.1
reactant: 056346
product: 056394
reactant: 056358
fast: false
product: 056382
reversible: false
product: 056430

100926
stoichiometry: 1.0
species: 040041
type: SpeciesReference

132449
stoichiometry: 1.0
species: 046440
type: SpeciesReference

105319
stoichiometry: 1.0
species: 040342
type: SpeciesReference

106740
stoichiometry: 1.0
species: 025505
type: SpeciesReference

050191
stoichiometry: 32.0
species: 034339
type: SpeciesReference

108984
stoichiometry: 1.0
species: 019779
type: SpeciesReference

053182
stoichiometry: 1.0
species: 026953
type: SpeciesReference

135325
stoichiometry: 1.0
species: 033275
type: SpeciesReference

141728
stoichiometry: 2.0
species: 034026
type: SpeciesReference

023659
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: N-Acetyl-D-mannosamine_C8H15NO6
type: Species

045093
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: tetracosapentaenoic acid, n-3_C24H37O2
type: Species

121464
stoichiometry: 1.0
species: 040126
type: SpeciesReference

070478
stoichiometry: 1.0
species: 034363
type: SpeciesReference

103873
stoichiometry: 1.0
species: 034532
type: SpeciesReference

058929
stoichiometry: 1.0
species: 026469
type: SpeciesReference

068706
stoichiometry: 1.0
species: 021979
type: SpeciesReference

149410
stoichiometry: 1.0
species: 032112
type: SpeciesReference

063959
stoichiometry: 1.0
species: 023877
type: SpeciesReference

105644
stoichiometry: 5.0
species: 045573
type: SpeciesReference

057239
stoichiometry: 1.0
species: 023780
type: SpeciesReference

055051
stoichiometry: 4.0
species: 027145
type: SpeciesReference

025408
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Ascorbate_C6H8O6
type: Species

114503
stoichiometry: 3.0
species: 042283
type: SpeciesReference

071693
stoichiometry: 1.0
species: 034253
type: SpeciesReference

053724
stoichiometry: 1.0
species: 030880
type: SpeciesReference

068077
stoichiometry: 2.0
species: 044319
type: SpeciesReference

142548
stoichiometry: 1.0
species: 034436
type: SpeciesReference

142813
stoichiometry: 2.0
species: 042548
type: SpeciesReference

926105
name: alpha,alpha-trehalase
product: 070791
reactant: 070779
is: ENSMMUG00000004625.2
reversible: false
reactant: 070767
notes: R_TREH subsystem: Starch and Sucrose Metabolism R_TREH equation: [c] : h2o + tre --> (2) glc-D
is: http://identifiers.org/ec-code/3.2.1.28
fast: false
type: Reaction

026941
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
type: Species

135953
stoichiometry: 3.0
species: 038634
type: SpeciesReference

120153
stoichiometry: 1.0
species: 030686
type: SpeciesReference

087329
stoichiometry: 1.0
species: 043572
type: SpeciesReference

107148
stoichiometry: 1.0
species: 040150
type: SpeciesReference

147503
stoichiometry: 2.0
species: 031339
type: SpeciesReference

108886
stoichiometry: 1.0
species: 039993
type: SpeciesReference

032524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Glucosamine_C6H14NO5
type: Species

107292
stoichiometry: 1.0
species: 034436
type: SpeciesReference

926465
reactant: 073274
product: 073286
name: phospholipase
reactant: 073262
notes: R_LPS4e subsystem: Triacylglycerol Synthesis R_LPS4e equation: [e] : h2o + pglyc_hs --> 1glyc_hs + Rtotal2 + h
product: 073298
reversible: false
product: 073311
fast: false
type: Reaction
is: ENSMMUG00000031036.1

097948
stoichiometry: 1.0
species: 039499
type: SpeciesReference

026191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: (E)-carveol_C10H16O
type: Species

137688
stoichiometry: 1.0
species: 031133
type: SpeciesReference

925072
product: 061502
product: 061562
modifier: 061646
reactant: 061394
product: 061490
reactant: 061310
reactant: 061430
reactant: 061322
fast: false
product: 061478
modifier: 061658
modifier: 061598
product: 061514
modifier: 061706
is: http://identifiers.org/ec-code/1.8.1.4
is: http://identifiers.org/ec-code/1.2.4.1
modifier: 061634
reactant: 061370
modifier: 061622
reactant: 061382
product: 061454
is: http://identifiers.org/ec-code/1.4.4.2
product: 061574
modifier: 061586
notes: R_GCCbim subsystem: Glycine, Serine, and Threonine Metabolism R_GCCbim equation: [m] : alpro + thf --> dhlpro + mlthf + nh4 R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh R_OIVD2m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD2m equation: [m] : 3mob + coa + nad --> co2 + ibcoa + nadh R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_GCCcm subsystem: Glycine, Serine, and Threonine Metabolism R_GCCcm equation: [m] : dhlpro + nad <==> h + lpro + nadh R_GCC2bim subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2bim equation: [m] : alpam + thf --> dhlam + mlthf + nh4 R_OIVD3m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD3m equation: [m] : 3mop + coa + nad --> 2mbcoa + co2 + nadh R_GCCam subsystem: Glycine, Serine, and Threonine Metabolism R_GCCam equation: [m] : gly + h + lpro <==> alpro + co2 R_GCC2cm subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2cm equation: [m] : dhlam + nad <==> h + lpam + nadh R_OIVD1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD1m equation: [m] : 4mop + coa + nad --> co2 + ivcoa + nadh R_GCC2am subsystem: Glycine, Serine, and Threonine Metabolism R_GCC2am equation: [m] : gly + h + lpam <==> alpam + co2 R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
product: 061550
type: Reaction
modifier: 061682
modifier: 061610
is: http://identifiers.org/ec-code/1.2.4.2
product: 061538
reactant: 061358
reactant: 061406
product: 061466
is: ENSMMUG00000006564.2
reactant: 061418
product: 061526
is: http://identifiers.org/ec-code/1.2.1.25
modifier: 061694
reversible: false
is: http://identifiers.org/ec-code/2.1.2.10
modifier: 061670
reactant: 061334
product: 061442
reactant: 061346

030892
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Estrone_C18H22O2
type: Species

932943
is: ENSMMUG00000018364.2
product: 136229
product: 136217
reactant: 136121
reactant: 136145
reactant: 136193
reactant: 136169
product: 136253
product: 136205
type: Reaction
product: 136241
is: http://identifiers.org/ec-code/1.14.14.1
reactant: 136133
reactant: 136157
reactant: 136181
fast: false
product: 136265
reactant: 136109
reversible: false
notes: R_P4502F1 subsystem: CYP Metabolism R_P4502F1 equation: [c] : h + nadph + npthl + o2 --> h2o + nadp + onpthl R_P4504B1r subsystem: Eicosanoid Metabolism R_P4504B1r equation: [r] : arachd + h + nadph + o2 --> 12harachd + h2o + nadp

118883
stoichiometry: 6.0
species: 034532
type: SpeciesReference

117198
stoichiometry: 2.0
species: 034363
type: SpeciesReference

065993
stoichiometry: 1.0
species: 019731
type: SpeciesReference

106956
stoichiometry: 1.0
species: 020762
type: SpeciesReference

028607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Decanoyl-CoA (n-C10:0CoA)_C31H50N7O17P3S
type: Species

096249
stoichiometry: 2.0
species: 034363
type: SpeciesReference

084290
stoichiometry: 2.0
species: 034265
type: SpeciesReference

076857
stoichiometry: 1.0
species: 042139
type: SpeciesReference

034051
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Reduced glutathione_C10H16N3O6S
type: Species

048127
stoichiometry: 1.0
species: 035145
type: SpeciesReference

121259
stoichiometry: 2.0
species: 042355
type: SpeciesReference

062355
stoichiometry: 1.0
species: 032524
type: SpeciesReference

031846
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO
type: Species

048476
stoichiometry: 1.0
species: 034253
type: SpeciesReference

144053
stoichiometry: 2.0
species: 024658
type: SpeciesReference

130407
stoichiometry: 1.0
species: 037729
type: SpeciesReference

928134
product: 088402
is: http://identifiers.org/ec-code/3.5.4.16
notes: R_GTPCI subsystem: Tetrahydrobiopterin R_GTPCI equation: [c] : gtp + h2o --> ahdt + for + h R_GTPCIn subsystem: Tetrahydrobiopterin R_GTPCIn equation: [n] : gtp + h2o --> ahdt + for + h
product: 088438
reactant: 088342
reactant: 088366
product: 088414
product: 088390
product: 088378
product: 088426
is: ENSMMUG00000004084.2
reactant: 088330
reactant: 088354
fast: false
reversible: false
type: Reaction

036029
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Inosine_C10H12N4O5
type: Species

066834
stoichiometry: 16.0
species: 032923
type: SpeciesReference

027759
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 1_C45H68N2O43S2
type: Species

121896
stoichiometry: 1.0
species: 038959
type: SpeciesReference

102783
stoichiometry: 1.0
species: 039008
type: SpeciesReference

113284
stoichiometry: 1.0
species: 023102
type: SpeciesReference

146431
stoichiometry: 1.0
species: 020678
type: SpeciesReference

927725
product: 085337
is: http://identifiers.org/ec-code/3.2.1.46
fast: false
type: Reaction
notes: R_GALC subsystem: Sphingolipid Metabolism R_GALC equation: [l] : galside_hs + h2o --> crm_hs + gal
reactant: 085300
is: ENSMMUG00000017261.2
reversible: false
name: Galactocerebrosidase
reactant: 085313
product: 085325

146107
stoichiometry: 1.0
species: 027833
type: SpeciesReference

061490
stoichiometry: 1.0
species: 033215
type: SpeciesReference

045911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Tryptophan_C11H12N2O2
type: Species

047045
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3alpha,7alpha-Dihydroxy-5beta-cholestane_C27H48O2
type: Species

933279
reactant: 138579
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal
reactant: 138603
is: http://identifiers.org/ec-code/1.1.1.105
type: Reaction
reversible: true
reactant: 138591
product: 138663
product: 138651
is: ENSMMUG00000014810.2
is: ENSMMUG00000014811.2
product: 138627
product: 138615
reactant: 138567
product: 138639
fast: false
is: ENSMMUG00000022322.2
is: ENSMMUG00000015869.2
is: ENSMMUG00000015868.2
is: ENSMMUG00000011897.1

081515
stoichiometry: 1.0
species: 024118
type: SpeciesReference

075059
stoichiometry: 1.0
species: 034063
type: SpeciesReference

037208
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate II (core 2-linked), degradation product 2_C70H114N5O56S2X
type: Species

033640
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: GMP_C10H12N5O8P
type: Species

039595
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2
type: Species

111849
stoichiometry: 1.0
species: 045369
type: SpeciesReference

083157
stoichiometry: 1.0
species: 030078
type: SpeciesReference

116522
stoichiometry: 1.0
species: 046695
type: SpeciesReference

089210
stoichiometry: 2.0
species: 031677
type: SpeciesReference

131376
stoichiometry: 1.0
species: 032560
type: SpeciesReference

069683
stoichiometry: 1.0
species: 034460
type: SpeciesReference

064223
stoichiometry: 2.0
species: 042956
type: SpeciesReference

136723
stoichiometry: 1.0
species: 038309
type: SpeciesReference

087643
stoichiometry: 1.0
species: 027978
type: SpeciesReference

067667
stoichiometry: 1.0
species: 025541
type: SpeciesReference

140496
stoichiometry: 1.0
species: 037790
type: SpeciesReference

112345
stoichiometry: 2.0
species: 025541
type: SpeciesReference

127038
stoichiometry: 1.0
species: 037983
type: SpeciesReference

149981
stoichiometry: 1.0
species: 031229
type: SpeciesReference

102350
stoichiometry: 1.0
species: 033021
type: SpeciesReference

123301
stoichiometry: 1.0
species: 033640
type: SpeciesReference

144706
stoichiometry: 1.0
species: 044585
type: SpeciesReference

143789
stoichiometry: 1.0
species: 032440
type: SpeciesReference

098572
stoichiometry: 1.0
species: 038200
type: SpeciesReference

049298
stoichiometry: 1.0
species: 035824
type: SpeciesReference

122641
stoichiometry: 1.0
species: 039595
type: SpeciesReference

122364
stoichiometry: 1.0
species: 027181
type: SpeciesReference

930300
reactant: 109381
name: _5-formethyltetrahydrofolate cyclo-ligase
notes: R_FTHFCL subsystem: Folate Metabolism R_FTHFCL equation: [c] : 5fthf + atp --> adp + methf + pi
fast: false
reversible: false
product: 109417
type: Reaction
is: ENSMMUG00000015224.2
product: 109393
is: http://identifiers.org/ec-code/6.3.3.2
reactant: 109369
product: 109405

097359
stoichiometry: 1.0
species: 046779
type: SpeciesReference

056962
stoichiometry: 1.0
species: 046719
type: SpeciesReference

040837
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: O2_O2
type: Species

042343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Phosphate_HO4P
type: Species

057552
stoichiometry: 1.0
species: 040270
type: SpeciesReference

085313
stoichiometry: 1.0
species: 032476
type: SpeciesReference

050842
stoichiometry: 2.0
species: 040174
type: SpeciesReference

927077
product: 078693
reactant: 078681
name: gamma-glutamylcyclotransferase
is: http://identifiers.org/ec-code/2.3.2.4
is: ENSMMUG00000012550.2
notes: R_GGLUCT subsystem: Glutathione Metabolism R_GGLUCT equation: gluala[e] --> 5oxpro[c] + ala-L[c]
product: 078705
reversible: false
type: Reaction
fast: false

093847
stoichiometry: 3.0
species: 034363
type: SpeciesReference

049419
stoichiometry: 1.0
species: 032765
type: SpeciesReference

105463
stoichiometry: 5.0
species: 025433
type: SpeciesReference

099512
stoichiometry: 1.0
species: 020179
type: SpeciesReference

073154
stoichiometry: 1.0
species: 025843
type: SpeciesReference

146732
stoichiometry: 1.0
species: 034605
type: SpeciesReference

052942
stoichiometry: 3.0
species: 024010
type: SpeciesReference

025288
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: C20:4-CoA_C41H62N7O17P3S
type: Species

082358
stoichiometry: 1.0
species: 026299
type: SpeciesReference

079106
stoichiometry: 1.0
species: 034363
type: SpeciesReference

055319
stoichiometry: 1.0
species: 037693
type: SpeciesReference

031762
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)3 (Glc)1 (GlcNAc)2 (LFuc)3 (Cer)1_C76H132N3O44FULLRCO
type: Species

075913
stoichiometry: 1.0
species: 029945
type: SpeciesReference

150391
stoichiometry: 1.0
species: 034881
type: SpeciesReference

119946
stoichiometry: 1.0
species: 038393
type: SpeciesReference

081407
stoichiometry: 1.0
species: 037886
type: SpeciesReference

139507
stoichiometry: 1.0
species: 024646
type: SpeciesReference

931837
product: 125616
product: 125640
reactant: 125568
product: 125628
reactant: 125592
reactant: 125580
is: ENSMMUG00000031203.1
fast: false
product: 125652
type: Reaction
reversible: false
product: 125664
reactant: 125604
notes: R_NTPP11 subsystem: Nucleotides R_NTPP11 equation: [c] : h2o + xtp --> h + ppi + xmp R_NTPP10 subsystem: Nucleotides R_NTPP10 equation: [c] : ditp + h2o --> dimp + h + ppi R_NTPP9 subsystem: Nucleotides R_NTPP9 equation: [c] : h2o + itp --> h + imp + ppi
is: http://identifiers.org/ec-code/3.6.1.19

090539
stoichiometry: 1.0
species: 045741
type: SpeciesReference

102910
stoichiometry: 1.0
species: 032911
type: SpeciesReference

934012
product: 147804
is: ENSMMUG00000001284.2
reactant: 147732
reversible: false
product: 147816
product: 147780
reactant: 147720
notes: R_ADNt4 subsystem: Transport, Extracellular R_ADNt4 equation: adn[e] + na1[e] --> adn[c] + na1[c] R_URIt4 subsystem: Transport, Extracellular R_URIt4 equation: na1[e] + uri[e] --> na1[c] + uri[c] R_INSt4 subsystem: Transport, Extracellular R_INSt4 equation: ins[e] + na1[e] --> ins[c] + na1[c] R_GSNt4 subsystem: Transport, Extracellular R_GSNt4 equation: gsn[e] + na1[e] --> gsn[c] + na1[c]
reactant: 147768
fast: false
type: Reaction
reactant: 147756
product: 147828
product: 147792
reactant: 147744

145358
stoichiometry: 1.0
species: 036570
type: SpeciesReference

041018
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S
type: Species

051564
stoichiometry: 1.0
species: 042187
type: SpeciesReference

045803
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Oxidized thioredoxin_X
type: Species

134568
stoichiometry: 1.0
species: 029957
type: SpeciesReference

084277
stoichiometry: 1.0
species: 040210
type: SpeciesReference

132100
stoichiometry: 1.0
species: 033628
type: SpeciesReference

128281
stoichiometry: 1.0
species: 044174
type: SpeciesReference

113960
stoichiometry: 1.0
species: 037597
type: SpeciesReference

063610
stoichiometry: 1.0
species: 032221
type: SpeciesReference

135794
stoichiometry: 1.0
species: 038682
type: SpeciesReference

094125
stoichiometry: 1.0
species: 031013
type: SpeciesReference

058941
stoichiometry: 1.0
species: 025685
type: SpeciesReference

138254
stoichiometry: 1.0
species: 037693
type: SpeciesReference

076423
stoichiometry: 1.0
species: 037729
type: SpeciesReference

020143
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Glycerate 2-phosphate_C3H4O7P
type: Species

079830
stoichiometry: 1.0
species: 045561
type: SpeciesReference

118354
stoichiometry: 1.0
species: 040921
type: SpeciesReference

119886
stoichiometry: 1.0
species: 035025
type: SpeciesReference

051686
stoichiometry: 1.0
species: 044875
type: SpeciesReference

107353
stoichiometry: 1.0
species: 046415
type: SpeciesReference

031616
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: III3Fuc-nLc6Cer_C64H112N3O36FULLRCO
type: Species

028836
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Deoxycytidine_C9H13N3O4
type: Species

021991
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

145577
stoichiometry: 1.0
species: 027602
type: SpeciesReference

140762
stoichiometry: 8.0
species: 034375
type: SpeciesReference

142693
stoichiometry: 1.0
species: 043644
type: SpeciesReference

923560
name: lipase
is: http://identifiers.org/ec-code/3.1.1.23
product: 047585
notes: R_LPS3 subsystem: Triacylglycerol Synthesis R_LPS3 equation: [c] : h2o + mag_hs --> Rtotal2 + glyc + h
type: Reaction
reactant: 047537
reactant: 047549
reversible: false
fast: false
product: 047561
is: ENSMMUG00000000168.2
product: 047573

032560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: globoside (homo sapiens)_C44H79N2O22FULLRCO
type: Species

126062
stoichiometry: 1.0
species: 041814
type: SpeciesReference

083410
stoichiometry: 3.0
species: 034253
type: SpeciesReference

924316
product: 054221
is: ENSMMUG00000011916.2
is: ENSMMUG00000018235.2
is: ENSMMUG00000022947.2
fast: false
is: http://identifiers.org/ec-code/4.2.1.11
reactant: 054196
name: enolase
reversible: true
type: Reaction
is: ENSMMUG00000012567.2
product: 054208
notes: R_ENO subsystem: Glycolysis/Gluconeogenesis R_ENO equation: [c] : 2pg <==> h2o + pep
is: ENSMMUG00000012040.1
is: ENSMMUG00000032242.1

929515
product: 102639
reactant: 102627
notes: R_TYRASE subsystem: Tyrosine metabolism R_TYRASE equation: [c] : 56dihindlcrbxlt --> melanin
is: ENSMMUG00000013288.2
fast: false
reversible: false
name: Tyrosinase
type: Reaction

142162
stoichiometry: 1.0
species: 019421
type: SpeciesReference

059726
stoichiometry: 1.0
species: 028752
type: SpeciesReference

124422
stoichiometry: 2.0
species: 033119
type: SpeciesReference

141161
stoichiometry: 7.0
species: 034412
type: SpeciesReference

040717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: nervonyl coenzyme A_C45H76N7O17P3S
type: Species

099947
stoichiometry: 1.0
species: 019524
type: SpeciesReference

110511
stoichiometry: 1.0
species: 033131
type: SpeciesReference

112466
stoichiometry: 1.0
species: 023162
type: SpeciesReference

924460
type: Reaction
reversible: true
is: ENSMMUG00000008294.2
reactant: 055404
product: 055440
product: 055428
notes: R_GTHPm subsystem: Glutathione Metabolism R_GTHPm equation: [m] : (2) gthrd + h2o2 <==> gthox + (2) h2o
is: http://identifiers.org/ec-code/1.11.1.9
is: ENSMMUG00000004923.2
reactant: 055416
fast: false
name: glutathione peroxidase, mitochondria

148613
stoichiometry: 1.0
species: 024166
type: SpeciesReference

101107
stoichiometry: 2.0
species: 023162
type: SpeciesReference

143909
stoichiometry: 1.0
species: 026335
type: SpeciesReference

068283
stoichiometry: 1.0
species: 024010
type: SpeciesReference

058084
stoichiometry: 1.0
species: 037766
type: SpeciesReference

114383
stoichiometry: 3.0
species: 032016
type: SpeciesReference

086266
stoichiometry: 1.0
species: 038562
type: SpeciesReference

025142
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Adenosine 5'-phosphosulfate_C10H12N5O10PS
type: Species

118570
stoichiometry: 7.0
species: 028716
type: SpeciesReference

930071
reactant: 107160
type: Reaction
product: 107184
notes: R_PIt2m subsystem: Transport, Mitochondrial R_PIt2m equation: h[c] + pi[c] <==> h[m] + pi[m]
is: ENSMMUG00000023036.2
reversible: true
fast: false
product: 107196
reactant: 107172
name: phosphate transporter, mitochondrial

030686
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Elaidic carnitine_C25H47NO4
type: Species

024046
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: ADP_C10H12N5O10P2
type: Species

034761
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _4,17 dihydroxy estradiol_C18H24O3
type: Species

127789
stoichiometry: 1.0
species: 032887
type: SpeciesReference

072962
stoichiometry: 1.0
species: 032923
type: SpeciesReference

127256
stoichiometry: 1.0
species: 029909
type: SpeciesReference

143441
stoichiometry: 1.0
species: 037487
type: SpeciesReference

930881
modifier: 116582
modifier: 116704
modifier: 116764
modifier: 116630
modifier: 116800
modifier: 116618
modifier: 116752
type: Reaction
modifier: 116692
modifier: 116679
modifier: 116643
modifier: 116812
reversible: false
modifier: 116594
modifier: 116716
modifier: 116776
modifier: 116728
reactant: 116546
is: ENSMMUG00000015984.2
modifier: 116788
product: 116558
modifier: 116655
notes: R_ADNt subsystem: Transport, Extracellular R_ADNt equation: adn[e] <==> adn[c] R_INSt subsystem: Transport, Extracellular R_INSt equation: ins[e] <==> ins[c] R_HYXNt subsystem: Transport, Extracellular R_HYXNt equation: hxan[e] <==> hxan[c] R_URIt subsystem: Transport, Extracellular R_URIt equation: uri[e] <==> uri[c] R_GSNt subsystem: Transport, Extracellular R_GSNt equation: gsn[e] <==> gsn[c] R_CSNt subsystem: Transport, Extracellular R_CSNt equation: csn[e] <==> csn[c] R_URAt subsystem: Transport, Extracellular R_URAt equation: ura[e] <==> ura[c] R_ADEt subsystem: Transport, Extracellular R_ADEt equation: ade[e] <==> ade[c] R_GUAt subsystem: Transport, Extracellular R_GUAt equation: gua[e] <==> gua[c] R_THYMt subsystem: Transport, Extracellular R_THYMt equation: thym[e] <==> thym[c] R_THYMDt1 subsystem: Transport, Extracellular R_THYMDt1 equation: thymd[e] --> thymd[c] R_CYTDt subsystem: Transport, Extracellular R_CYTDt equation: cytd[e] <==> cytd[c]
modifier: 116570
modifier: 116606
modifier: 116740
modifier: 116824
fast: false
modifier: 116667

053880
stoichiometry: 1.0
species: 037499
type: SpeciesReference

030394
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dUMP_C9H11N2O8P
type: Species

044162
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Serine_C3H7NO3
type: Species

143116
stoichiometry: 1.0
species: 036317
type: SpeciesReference

097503
stoichiometry: 1.0
species: 040306
type: SpeciesReference

149835
stoichiometry: 1.0
species: 023211
type: SpeciesReference

133293
stoichiometry: 1.0
species: 044560
type: SpeciesReference

123493
stoichiometry: 1.0
species: 025348
type: SpeciesReference

150403
stoichiometry: 1.0
species: 030078
type: SpeciesReference

151235
stoichiometry: 1.0
species: 033797
type: SpeciesReference

056817
stoichiometry: 1.0
species: 022752
type: SpeciesReference

056756
stoichiometry: 1.0
species: 028497
type: SpeciesReference

062018
stoichiometry: 2.0
species: 034412
type: SpeciesReference

132004
stoichiometry: 1.0
species: 029571
type: SpeciesReference

024901
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: AMP_C10H12N5O7P
type: Species

130928
stoichiometry: 1.0
species: 019524
type: SpeciesReference

108679
stoichiometry: 1.0
species: 037766
type: SpeciesReference

082032
stoichiometry: 1.0
species: 026432
type: SpeciesReference

110366
stoichiometry: 1.0
species: 043235
type: SpeciesReference

039128
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Mannose 1-phosphate_C6H11O9P
type: Species

054918
stoichiometry: 1.0
species: 038923
type: SpeciesReference

076797
stoichiometry: 1.0
species: 034253
type: SpeciesReference

933063
fast: false
is: ENSMMUG00000013435.2
is: ENSMMUG00000006443.2
is: ENSMMUG00000011266.2
is: ENSMMUG00000009529.2
notes: R_GAPD subsystem: Glycolysis/Gluconeogenesis R_GAPD equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh
is: ENSMMUG00000000295.2
is: ENSMMUG00000023544.2
product: 137508
is: ENSMMUG00000008461.2
is: ENSMMUG00000000837.1
reversible: true
is: ENSMMUG00000012016.2
is: ENSMMUG00000003028.2
is: ENSMMUG00000002973.2
name: glyceraldehyde-3-phosphate dehydrogenase
is: ENSMMUG00000002734.2
product: 137520
is: ENSMMUG00000018679.2
reactant: 137484
reactant: 137460
product: 137496
type: Reaction
is: ENSMMUG00000008712.2
reactant: 137472
is: ENSMMUG00000018635.2
is: http://identifiers.org/ec-code/1.2.1.12

932715
reversible: false
reactant: 134423
reactant: 134459
is: ENSMMUG00000006604.2
type: Reaction
reactant: 134435
notes: R_COQ7m subsystem: Ubiquinone Biosynthesis R_COQ7m equation: [m] : 2dp6mobq_me + h + nadph + o2 --> 2dpmhobq + h2o + nadp
product: 134495
product: 134471
reactant: 134447
name: Ubiquinone biosynthesis COQ7
product: 134483
is: ENSMMUG00000011613.2
fast: false

084542
stoichiometry: 23.0
species: 040849
type: SpeciesReference

065753
stoichiometry: 2.0
species: 034253
type: SpeciesReference

103134
stoichiometry: 1.0
species: 035799
type: SpeciesReference

079505
stoichiometry: 1.0
species: 033021
type: SpeciesReference

931213
reactant: 120513
reactant: 120501
is: http://identifiers.org/ec-code/1.1.1.42
product: 120525
reversible: true
notes: R_ICDHyrm subsystem: Citric Acid Cycle R_ICDHyrm equation: [m] : icit + nadp <==> akg + co2 + nadph
type: Reaction
fast: false
product: 120537
name: Isocitrate dehydrogenase (NADP+)
is: ENSMMUG00000014833.2
product: 120549

087341
stoichiometry: 1.0
species: 032124
type: SpeciesReference

056310
stoichiometry: 1.0
species: 034363
type: SpeciesReference

119522
stoichiometry: 1.0
species: 035544
type: SpeciesReference

019791
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _2,3-Disphospho-D-glycerate_C3H3O10P2
type: Species

098344
stoichiometry: 1.0
species: 042415
type: SpeciesReference

108305
stoichiometry: 3.0
species: 025565
type: SpeciesReference

035423
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 11_C79H121N5O77S4X
type: Species

059879
stoichiometry: 1.0
species: 035677
type: SpeciesReference

137845
stoichiometry: 1.0
species: 034363
type: SpeciesReference

094463
stoichiometry: 4.0
species: 040077
type: SpeciesReference

096456
stoichiometry: 1.0
species: 038116
type: SpeciesReference

049634
stoichiometry: 2.0
species: 034436
type: SpeciesReference

934504
reversible: false
name: peroxisomal lumped long chain fatty acid oxidation
product: 151968
reactant: 151895
product: 151944
notes: R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa
product: 151908
reactant: 151859
reactant: 151871
product: 151956
fast: false
is: ENSMMUG00000006234.2
reactant: 151847
product: 151932
product: 151920
type: Reaction
reactant: 151883

048681
stoichiometry: 1.0
species: 041766
type: SpeciesReference

110969
stoichiometry: 1.0
species: 020374
type: SpeciesReference

038501
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Lysine_C6H15N2O2
type: Species

048319
stoichiometry: 3.0
species: 034265
type: SpeciesReference

078886
stoichiometry: 1.0
species: 034363
type: SpeciesReference

142271
stoichiometry: 1.0
species: 021642
type: SpeciesReference

931102
product: 118630
reactant: 118450
fast: false
product: 118762
product: 118678
reactant: 118402
product: 118654
product: 118690
reactant: 118474
product: 118786
reactant: 118426
reactant: 118510
reactant: 118618
reactant: 118486
is: http://identifiers.org/ec-code/2.7.4.14
reactant: 118570
notes: R_CYTK5 subsystem: Nucleotides R_CYTK5 equation: [c] : ctp + dcmp <==> cdp + dcdp R_CYTK10n subsystem: Nucleotides R_CYTK10n equation: [n] : cmp + dgtp <==> cdp + dgdp R_CYTK6n subsystem: Nucleotides R_CYTK6n equation: [n] : cmp + ctp <==> (2) cdp R_CYTK6 subsystem: Nucleotides R_CYTK6 equation: [c] : cmp + ctp <==> (2) cdp R_UMPK5 subsystem: Nucleotides R_UMPK5 equation: [c] : datp + ump <==> dadp + udp R_CYTK11 subsystem: Nucleotides R_CYTK11 equation: [c] : dcmp + dgtp <==> dcdp + dgdp R_UMPK3n subsystem: Nucleotides R_UMPK3n equation: [n] : ump + utp <==> (2) udp R_UMPK6n subsystem: Nucleotides R_UMPK6n equation: [n] : dctp + ump <==> dcdp + udp R_CYTK14n subsystem: Nucleotides R_CYTK14n equation: [n] : dcmp + utp <==> dcdp + udp R_UMPK2 subsystem: Nucleotides R_UMPK2 equation: [c] : ctp + ump <==> cdp + udp R_CYTK2n subsystem: Nucleotides R_CYTK2n equation: [n] : atp + dcmp <==> adp + dcdp R_UMPK6 subsystem: Nucleotides R_UMPK6 equation: [c] : dctp + ump <==> dcdp + udp R_UMPK4 subsystem: Nucleotides R_UMPK4 equation: [c] : gtp + ump <==> gdp + udp R_CYTK2 subsystem: Nucleotides R_CYTK2 equation: [c] : atp + dcmp <==> adp + dcdp R_UMPK5n subsystem: Nucleotides R_UMPK5n equation: [n] : datp + ump <==> dadp + udp R_UMPK subsystem: Nucleotides R_UMPK equation: [c] : atp + ump <==> adp + udp R_CYTK13 subsystem: Nucleotides R_CYTK13 equation: [c] : datp + dcmp <==> dadp + dcdp R_CYTK13n subsystem: Nucleotides R_CYTK13n equation: [n] : datp + dcmp <==> dadp + dcdp R_UMPK2n subsystem: Nucleotides R_UMPK2n equation: [n] : ctp + ump <==> cdp + udp R_CYTK9n subsystem: Nucleotides R_CYTK9n equation: [n] : cmp + dctp <==> cdp + dcdp R_CYTK7n subsystem: Nucleotides R_CYTK7n equation: [n] : cmp + utp <==> cdp + udp R_CYTK7 subsystem: Nucleotides R_CYTK7 equation: [c] : cmp + utp <==> cdp + udp R_CYTK3n subsystem: Nucleotides R_CYTK3n equation: [n] : ctp + dcmp <==> cdp + dcdp R_CYTK1 subsystem: Nucleotides R_CYTK1 equation: [c] : atp + cmp <==> adp + cdp R_CYTK14 subsystem: …
reactant: 118606
reactant: 118414
is: ENSMMUG00000007151.1
reactant: 118594
product: 118714
product: 118642
reactant: 118438
product: 118774
product: 118726
reactant: 118522
reactant: 118498
is: ENSMMUG00000017375.2
reactant: 118582
reactant: 118534
reactant: 118558
type: Reaction
product: 118666
reversible: true
reactant: 118546
product: 118738
reactant: 118462
reactant: 118390
product: 118750
product: 118702

044597
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: stearoylcarnitine_C25H49NO4
type: Species

094946
stoichiometry: 1.0
species: 033021
type: SpeciesReference

140340
stoichiometry: 1.0
species: 037353
type: SpeciesReference

073214
stoichiometry: 1.0
species: 038513
type: SpeciesReference

040608
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Nitric oxide_NO
type: Species

051794
stoichiometry: 2.0
species: 025565
type: SpeciesReference

111161
stoichiometry: 1.0
species: 027723
type: SpeciesReference

129934
stoichiometry: 1.0
species: 034375
type: SpeciesReference

080046
stoichiometry: 1.0
species: 023247
type: SpeciesReference

093426
stoichiometry: 1.0
species: 033652
type: SpeciesReference

098128
stoichiometry: 8.0
species: 034363
type: SpeciesReference

059436
stoichiometry: 1.0
species: 034677
type: SpeciesReference

113127
stoichiometry: 1.0
species: 021775
type: SpeciesReference

100020
stoichiometry: 1.0
species: 023162
type: SpeciesReference

146504
stoichiometry: 10.0
species: 040150
type: SpeciesReference

112574
stoichiometry: 1.0
species: 033445
type: SpeciesReference

061070
stoichiometry: 6.0
species: 025541
type: SpeciesReference

063502
stoichiometry: 1.0
species: 034327
type: SpeciesReference

137809
stoichiometry: 2.0
species: 021618
type: SpeciesReference

044271
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Sulfite_O3S
type: Species

927497
reversible: false
type: Reaction
fast: false
is: ENSMMUG00000008942.2
is: http://identifiers.org/ec-code/3.4.13.3
product: 082867
notes: R_NBAHH_ir subsystem: beta-Alanine metabolism R_NBAHH_ir equation: [c] : carn + h2o --> ala-B + his-L
product: 082879
reactant: 082854
name: Nalpha-(beta-alanyl)-L-histidine hydrolase IR
reactant: 082842

050903
stoichiometry: 1.0
species: 041332
type: SpeciesReference

138494
stoichiometry: 2.0
species: 034277
type: SpeciesReference

929407
reactant: 101891
fast: false
is: ENSMMUG00000008728.2
reactant: 101903
reversible: false
product: 101939
product: 101927
product: 101951
notes: R_34DHPHAMT subsystem: Tyrosine metabolism R_34DHPHAMT equation: [c] : 34dhpha + amet --> ahcys + h + homoval R_DOPAMT subsystem: Tyrosine metabolism R_DOPAMT equation: [c] : amet + dopa --> 3moxtyr + ahcys + h R_SALMCOM subsystem: Tyrosine metabolism R_SALMCOM equation: [c] : amet + nrpphr --> ahcys + h + normete-L
type: Reaction
is: http://identifiers.org/ec-code/2.1.1.6
product: 101975
product: 101963
reactant: 101915
reactant: 101879

102097
stoichiometry: 1.0
species: 045911
type: SpeciesReference

105031
stoichiometry: 1.0
species: 031592
type: SpeciesReference

143225
stoichiometry: 1.0
species: 036449
type: SpeciesReference

056298
stoichiometry: 1.0
species: 027422
type: SpeciesReference

933688
product: 143068
product: 143030
reactant: 142994
product: 143043
reversible: false
reactant: 142970
is: http://identifiers.org/ec-code/1.14.99.3
is: ENSMMUG00000009901.2
is: ENSMMUG00000007221.2
type: Reaction
product: 143018
reactant: 143006
notes: R_HOXG subsystem: Heme Degradation R_HOXG equation: [c] : (5) h + (3) nadph + (3) o2 + pheme --> biliverd + co + fe2 + (3) h2o + (3) nadp
name: Heme oxygenase 1
fast: false
reactant: 142982
product: 143056

031013
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Ethanolamine phosphate_C2H7NO4P
type: Species

140653
stoichiometry: 3.0
species: 027025
type: SpeciesReference

043380
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Pyridoxamine_C8H13N2O2
type: Species

075266
stoichiometry: 4.0
species: 034387
type: SpeciesReference

091680
stoichiometry: 1.0
species: 042283
type: SpeciesReference

021883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Methoxyindoleacetate_C11H10NO3
type: Species

144811
stoichiometry: 1.0
species: 026904
type: SpeciesReference

928446
product: 093390
product: 093426
reactant: 093354
reactant: 093378
notes: R_PDE4g subsystem: Nucleotides R_PDE4g equation: [g] : 35cgmp + h2o --> gmp + h R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PDE1g subsystem: Nucleotides R_PDE1g equation: [g] : camp + h2o --> amp + h
reactant: 093342
product: 093438
reactant: 093318
reactant: 093330
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 093366
product: 093414
product: 093450
type: Reaction
is: ENSMMUG00000023614.2
reversible: false
fast: false
product: 093402

058482
stoichiometry: 1.0
species: 040162
type: SpeciesReference

042764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Pregnenolone_C21H32O2
type: Species

136579
stoichiometry: 1.0
species: 041163
type: SpeciesReference

084975
stoichiometry: 2.0
species: 045754
type: SpeciesReference

038839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)_C64H107N2O50X
type: Species

077304
stoichiometry: 1.0
species: 035920
type: SpeciesReference

148722
stoichiometry: 2.0
species: 047189
type: SpeciesReference

057939
stoichiometry: 1.0
species: 037790
type: SpeciesReference

086482
stoichiometry: 2.0
species: 038815
type: SpeciesReference

103025
stoichiometry: 1.0
species: 034387
type: SpeciesReference

039289
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: Methanol_CH4O1
type: Species

076363
stoichiometry: 1.0
species: 037754
type: SpeciesReference

024441
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide_C9H13N4O8P
type: Species

141462
stoichiometry: 4.0
species: 046235
type: SpeciesReference

087232
stoichiometry: 2.0
species: 041778
type: SpeciesReference

030454
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dUTP_C9H11N2O14P3
type: Species

932606
reactant: 133512
modifier: 133680
modifier: 133644
modifier: 133620
notes: R_THFt2 subsystem: Transport, Extracellular R_THFt2 equation: oh1[c] + thf[e] <==> oh1[e] + thf[c] R_FOLt2 subsystem: Transport, Extracellular R_FOLt2 equation: fol[e] + oh1[c] <==> fol[c] + oh1[e] R_5MTHFt2 subsystem: Transport, Extracellular R_5MTHFt2 equation: _5mthf[e] + oh1[c] <==> 5mthf[c] + oh1[e] R_THMMPt4 subsystem: Transport, Extracellular R_THMMPt4 equation: oh1[c] + thmmp[e] <==> oh1[e] + thmmp[c] R_THMTPt subsystem: Transport, Extracellular R_THMTPt equation: (3) oh1[e] + thmtp[c] --> (3) oh1[c] + thmtp[e] R_5FTHFt2 subsystem: Transport, Extracellular R_5FTHFt2 equation: _5fthf[e] + oh1[c] <==> 5fthf[c] + oh1[e]
product: 133536
modifier: 133668
fast: false
type: Reaction
modifier: 133608
modifier: 133584
modifier: 133560
reactant: 133524
modifier: 133572
modifier: 133632
is: ENSMMUG00000004477.2
reversible: false
product: 133548
modifier: 133596
modifier: 133692
modifier: 133656

054809
stoichiometry: 1.0
species: 038622
type: SpeciesReference

106728
stoichiometry: 1.0
species: 033082
type: SpeciesReference

076640
stoichiometry: 1.0
species: 033457
type: SpeciesReference

143333
stoichiometry: 1.0
species: 036389
type: SpeciesReference

121956
stoichiometry: 1.0
species: 022692
type: SpeciesReference

054159
stoichiometry: 1.0
species: 034265
type: SpeciesReference

110475
stoichiometry: 1.0
species: 037996
type: SpeciesReference

130819
stoichiometry: 1.0
species: 025154
type: SpeciesReference

045225
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: tetracosapentaenoyl carnitine_C31H51NO4
type: Species

108522
stoichiometry: 1.0
species: 040198
type: SpeciesReference

150512
stoichiometry: 1.0
species: 020216
type: SpeciesReference

092474
stoichiometry: 1.0
species: 043307
type: SpeciesReference

038610
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
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initial amount: NaN
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species: 036245
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species: 028448
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species: 023211
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species: 040789
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species: 042127
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species: 040150
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initial amount: NaN
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species: 020822
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species: 034315
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type: Species

121151
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species: 020894
type: SpeciesReference

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species: 035969
type: SpeciesReference

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species: 032789
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stoichiometry: 1.0
species: 035205
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2
type: Species

089367
stoichiometry: 1.0
species: 036944
type: SpeciesReference

132894
stoichiometry: 1.0
species: 040921
type: SpeciesReference

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stoichiometry: 3.0
species: 034253
type: SpeciesReference

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stoichiometry: 1.0
species: 030018
type: SpeciesReference

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stoichiometry: 1.0
species: 034363
type: SpeciesReference

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product: 057806
is: http://identifiers.org/ec-code/4.1.1.17
reactant: 057782
name: Ornithine Decarboxylase
fast: false
notes: R_ORNDC subsystem: Urea cycle/amino group metabolism R_ORNDC equation: [c] : h + orn --> co2 + ptrc
reversible: false
reactant: 057794
type: Reaction
product: 057818
is: ENSMMUG00000030822.1
is: ENSMMUG00000020441.2
is: ENSMMUG00000002927.2

128450
stoichiometry: 1.0
species: 029945
type: SpeciesReference

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stoichiometry: 1.0
species: 028014
type: SpeciesReference

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notes: R_ALOX15 subsystem: Eicosanoid Metabolism R_ALOX15 equation: [c] : arachd + o2 --> 15HPET
product: 088594
is: ENSMMUG00000030381.1
is: http://identifiers.org/ec-code/1.13.11.33
type: Reaction
reversible: false
reactant: 088570
name: Arachidonate 15-lipoxygenase
is: ENSMMUG00000009995.2
reactant: 088582
fast: false

096187
stoichiometry: 1.0
species: 021412
type: SpeciesReference

055259
stoichiometry: 1.0
species: 023297
type: SpeciesReference

128173
stoichiometry: 1.0
species: 034363
type: SpeciesReference

145006
stoichiometry: 1.0
species: 027662
type: SpeciesReference

049912
stoichiometry: 1.0
species: 027566
type: SpeciesReference

033058
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Glutamate 5-phosphate_C5H8NO7P
type: Species

118064
stoichiometry: 1.0
species: 025999
type: SpeciesReference

119100
stoichiometry: 6.0
species: 026977
type: SpeciesReference

125507
stoichiometry: 1.0
species: 023162
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1_C45H68N2O43S2
type: Species

140388
stoichiometry: 1.0
species: 037148
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _3'-AMP_C10H12N5O7P
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
type: Species

051456
stoichiometry: 1.0
species: 024525
type: SpeciesReference

136831
stoichiometry: 1.0
species: 038248
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Cholate_C24H39O5
type: Species

111739
stoichiometry: 1.0
species: 047081
type: SpeciesReference

116414
stoichiometry: 1.0
species: 021038
type: SpeciesReference

095944
stoichiometry: 1.0
species: 043091
type: SpeciesReference

086603
stoichiometry: 1.0
species: 038670
type: SpeciesReference

071258
stoichiometry: 1.0
species: 047285
type: SpeciesReference

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stoichiometry: 1.0
species: 034363
type: SpeciesReference

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stoichiometry: 1.0
species: 039414
type: SpeciesReference

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product: 100554
is: ENSMMUG00000003262.2
product: 100578
is: http://identifiers.org/ec-code/6.4.1.3
product: 100566
reactant: 100530
fast: false
type: Reaction
reactant: 100518
reversible: false
product: 100602
product: 100590
reactant: 100542
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PPCOACm subsystem: Valine, Leucine, and Isoleucine Metabolism R_PPCOACm equation: [m] : atp + hco3 + ppcoa --> adp + h + mmcoa-S + pi
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 100494
reactant: 100506
product: 100614

037316
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate II (core 2-linked)_C81H129N6O67S3X
type: Species

057661
stoichiometry: 2.0
species: 047333
type: SpeciesReference

927617
product: 084132
reactant: 083747
type: Reaction
product: 084035
reactant: 083699
is: ENSMMUG00000001940.2
reactant: 083807
reactant: 083795
reactant: 083735
product: 083987
reactant: 083783
reactant: 083723
product: 083975
product: 084011
product: 083915
reactant: 083843
reactant: 083831
product: 083879
product: 083927
product: 083891
reactant: 083639
reactant: 083819
product: 083939
product: 084096
reactant: 083627
fast: false
reactant: 083615
product: 083999
reactant: 083867
reactant: 083663
product: 084047
is: http://identifiers.org/ec-code/2.7.4.6
product: 084120
reactant: 083855
reactant: 083651
product: 083951
product: 084108
product: 084084
reactant: 083711
reactant: 083771
product: 083963
product: 084071
product: 083903
reversible: true
notes: R_NDPK9 subsystem: Nucleotides R_NDPK9 equation: [c] : atp + idp <==> adp + itp R_NDPK6n subsystem: Nucleotides R_NDPK6n equation: [n] : atp + dudp <==> adp + dutp R_NDPK8n subsystem: Nucleotides R_NDPK8n equation: [n] : atp + dadp <==> adp + datp R_NDPK3n subsystem: Nucleotides R_NDPK3n equation: [n] : atp + cdp <==> adp + ctp R_NDPK7n subsystem: Nucleotides R_NDPK7n equation: [n] : atp + dcdp <==> adp + dctp R_NDPK8 subsystem: Nucleotides R_NDPK8 equation: [c] : atp + dadp <==> adp + datp R_NDPK2 subsystem: Nucleotides R_NDPK2 equation: [c] : atp + udp <==> adp + utp R_NDPK6 subsystem: Nucleotides R_NDPK6 equation: [c] : atp + dudp <==> adp + dutp R_NDPK2n subsystem: Nucleotides R_NDPK2n equation: [n] : atp + udp <==> adp + utp R_NDPK5 subsystem: Nucleotides R_NDPK5 equation: [c] : atp + dgdp <==> adp + dgtp R_NDPK3 subsystem: Nucleotides R_NDPK3 equation: [c] : atp + cdp <==> adp + ctp R_NDPK4 subsystem: Nucleotides R_NDPK4 equation: [c] : atp + dtdp <==> adp + dttp R_NDPK10n subsystem: Nucleotides R_NDPK10n equation: [n] : atp + didp <==> adp + ditp R_NDPK1 subsystem: Nucleotides R_NDPK1 equation: [c] : atp + gdp <==> adp + gtp R_NDPK7 subsystem: Nucleotides R_NDPK7 equation: [c] : atp + dcdp <==> adp + dctp R_NDPK10 subsystem: Nucleotides R_NDPK10 equation: [c] : atp + didp <==> adp + ditp R_NDPK4n subsystem: Nucleotides R_NDPK4n equation: [n] : atp + dtdp <==> adp + dttp R_NDPK9n subsystem: Nucleotides R_NDPK9n equation: [n] : atp + idp <==> adp + itp R_NDPK5n subsystem: Nucleotides R_NDPK5n equation: [n] : atp + dgdp <==> adp + dgtp R_NDPK1n subsystem: Nucleotides R_NDPK1n equation: [n] : atp + gdp <==> adp + gtp
product: 084023
reactant: 083687
reactant: 083759
reactant: 083675
product: 084059

933123
product: 137821
notes: R_PPBNGS subsystem: Heme Biosynthesis R_PPBNGS equation: [c] : (2) 5aop --> h + (2) h2o + ppbng
type: Reaction
fast: false
product: 137845
name: porphobilinogen synthase
is: ENSMMUG00000031965.1
reactant: 137809
reversible: false
is: http://identifiers.org/ec-code/4.2.1.24
product: 137833

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stoichiometry: 1.0
species: 034387
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: pentaglutamyl folate (DHF)_C39H43N11O18
type: Species

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one_C27H46O3
type: Species

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stoichiometry: 1.0
species: 032609
type: SpeciesReference

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stoichiometry: 1.0
species: 021147
type: SpeciesReference

145152
stoichiometry: 1.0
species: 027894
type: SpeciesReference

121740
stoichiometry: 1.0
species: 023370
type: SpeciesReference

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stoichiometry: 1.0
species: 039716
type: SpeciesReference

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product: 051036
fast: false
name: Se-Adenosylselenohomocysteine hydrolase
reactant: 051000
reversible: false
is: ENSMMUG00000016306.2
is: ENSMMUG00000019358.2
notes: R_SEAHCYSHYD subsystem: Selenoamino acid metabolism R_SEAHCYSHYD equation: [c] : h2o + seahcys --> adn + selhcys
type: Reaction
is: http://identifiers.org/ec-code/3.3.1.1
product: 051024
reactant: 051012

089088
stoichiometry: 1.0
species: 025541
type: SpeciesReference

065464
stoichiometry: 1.0
species: 037148
type: SpeciesReference

138615
stoichiometry: 1.0
species: 043632
type: SpeciesReference

080313
stoichiometry: 1.0
species: 041054
type: SpeciesReference

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stoichiometry: 1.0
species: 037790
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4
type: Species

138760
stoichiometry: 3.0
species: 040837
type: SpeciesReference

150282
stoichiometry: 1.0
species: 032440
type: SpeciesReference

138362
stoichiometry: 1.0
species: 029981
type: SpeciesReference

065199
stoichiometry: 1.0
species: 033119
type: SpeciesReference

131594
stoichiometry: 1.0
species: 023382
type: SpeciesReference

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stoichiometry: 3.0
species: 034315
type: SpeciesReference

093198
stoichiometry: 1.0
species: 046307
type: SpeciesReference

052833
stoichiometry: 1.0
species: 041681
type: SpeciesReference

128850
stoichiometry: 1.0
species: 034253
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Cob(II)alamin_C62H92CoN13O14P
type: Species

146889
stoichiometry: 1.0
species: 045621
type: SpeciesReference

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stoichiometry: 1.0
species: 028146
type: SpeciesReference

107594
stoichiometry: 1.0
species: 030771
type: SpeciesReference

141896
stoichiometry: 1.0
species: 042151
type: SpeciesReference

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stoichiometry: 1.0
species: 034327
type: SpeciesReference

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stoichiometry: 1.0
species: 029283
type: SpeciesReference

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stoichiometry: 1.0
species: 039341
type: SpeciesReference

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stoichiometry: 14.0
species: 040150
type: SpeciesReference

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stoichiometry: 2.0
species: 043211
type: SpeciesReference

139869
stoichiometry: 1.0
species: 037560
type: SpeciesReference

071595
stoichiometry: 1.0
species: 043343
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10
type: Species

136169
stoichiometry: 1.0
species: 040789
type: SpeciesReference

094234
stoichiometry: 1.0
species: 039776
type: SpeciesReference

119450
stoichiometry: 1.0
species: 035519
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)2-Xyl-L-Ser (protein)_C17H29O14X
type: Species

084386
stoichiometry: 1.0
species: 041417
type: SpeciesReference

049840
stoichiometry: 1.0
species: 032609
type: SpeciesReference

077942
stoichiometry: 1.0
species: 042620
type: SpeciesReference

078015
stoichiometry: 1.0
species: 039487
type: SpeciesReference

055669
stoichiometry: 1.0
species: 026710
type: SpeciesReference

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stoichiometry: 2.0
species: 031290
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Lactate_C3H5O3
type: Species

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product: 139121
reactant: 139097
reactant: 139085
reversible: true
type: Reaction
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_GLCt2r subsystem: Transport, Extracellular R_GLCt2r equation: glc-D[e] + h[e] <==> glc-D[c] + h[c]
reactant: 139109
product: 139146
is: ENSMMUG00000000897.1
product: 139134
fast: false

071705
stoichiometry: 1.0
species: 023066
type: SpeciesReference

020484
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
type: Species

109489
stoichiometry: 2.0
species: 027218
type: SpeciesReference

022607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: R total 2 position_CO2FULLR2
type: Species

062440
stoichiometry: 1.0
species: 036185
type: SpeciesReference

034290
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: H2O_H2O
type: Species

079250
stoichiometry: 1.0
species: 025613
type: SpeciesReference

135229
stoichiometry: 1.0
species: 040837
type: SpeciesReference

052616
stoichiometry: 1.0
species: 030503
type: SpeciesReference

092186
stoichiometry: 1.0
species: 045729
type: SpeciesReference

151908
stoichiometry: 1.0
species: 029801
type: SpeciesReference

057119
stoichiometry: 2.0
species: 034253
type: SpeciesReference

128704
stoichiometry: 2.0
species: 034375
type: SpeciesReference

115893
stoichiometry: 1.0
species: 030345
type: SpeciesReference

142958
stoichiometry: 1.0
species: 044533
type: SpeciesReference

059001
stoichiometry: 1.0
species: 045778
type: SpeciesReference

066270
stoichiometry: 1.0
species: 031580
type: SpeciesReference

025709
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Bilirubin beta-diglucuronide_C45H50N4O18
type: Species

058337
stoichiometry: 1.0
species: 025541
type: SpeciesReference

106620
stoichiometry: 3.0
species: 034375
type: SpeciesReference

068609
stoichiometry: 18.0
species: 033107
type: SpeciesReference

926561
product: 074651
reactant: 074639
notes: R_PGI subsystem: Glycolysis/Gluconeogenesis R_PGI equation: [c] : g6p <==> f6p
is: ENSMMUG00000005880.2
is: http://identifiers.org/ec-code/5.3.1.9
fast: false
reversible: true
name: glucose-6-phosphate isomerase
type: Reaction

026071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
type: Species

078172
stoichiometry: 1.0
species: 034581
type: SpeciesReference

931321
modifier: 121560
product: 121476
reactant: 121452
is: ENSMMUG00000031999.1
reactant: 121440
reactant: 121428
reversible: false
modifier: 121572
reactant: 121464
product: 121512
modifier: 121548
product: 121488
modifier: 121524
notes: R_PGLer subsystem: Pentose Phosphate Pathway R_PGLer equation: [r] : 6pgl + h2o --> 6pgc + h R_G6PDH2rer subsystem: Pentose Phosphate Pathway R_G6PDH2rer equation: [r] : g6p + nadp <==> 6pgl + h + nadph R_G6PDH1rer subsystem: Pentose Phosphate Pathway R_G6PDH1rer equation: [r] : g6p + nad <==> 6pgl + h + nadh R_G6PDH1er subsystem: Pentose Phosphate Pathway R_G6PDH1er equation: [r] : g6p + nad --> 6pgl + h + nadh
modifier: 121584
type: Reaction
product: 121500
modifier: 121536
is: ENSMMUG00000002213.2
modifier: 121596
fast: false
is: http://identifiers.org/ec-code/3.1.1.31

075484
stoichiometry: 1.0
species: 029283
type: SpeciesReference

133819
stoichiometry: 2.0
species: 046187
type: SpeciesReference

078453
stoichiometry: 1.0
species: 024010
type: SpeciesReference

065873
stoichiometry: 1.0
species: 040584
type: SpeciesReference

061838
stoichiometry: 2.0
species: 034363
type: SpeciesReference

100298
stoichiometry: 1.0
species: 027218
type: SpeciesReference

074531
stoichiometry: 4.0
species: 044283
type: SpeciesReference

093570
stoichiometry: 1.0
species: 022425
type: SpeciesReference

934444
notes: R_HMGLx subsystem: Cholesterol Metabolism R_HMGLx equation: [x] : hmgcoa --> acac + accoa R_HMGLm subsystem: Cholesterol Metabolism R_HMGLm equation: [m] : hmgcoa --> acac + accoa
product: 151403
type: Reaction
product: 151415
reversible: false
reactant: 151379
product: 151427
fast: false
is: ENSMMUG00000019548.2
product: 151391
is: http://identifiers.org/ec-code/4.1.3.4
reactant: 151367

097059
stoichiometry: 1.0
species: 034253
type: SpeciesReference

022957
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: Tn antigen_C8H14NO5X
type: Species

062234
stoichiometry: 1.0
species: 039164
type: SpeciesReference

027350
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Creatine_C4H9N3O2
type: Species

138917
stoichiometry: 1.0
species: 019659
type: SpeciesReference

130200
stoichiometry: 1.0
species: 043428
type: SpeciesReference

057830
stoichiometry: 1.0
species: 024010
type: SpeciesReference

143006
stoichiometry: 3.0
species: 040270
type: SpeciesReference

073432
stoichiometry: 1.0
species: 025215
type: SpeciesReference

031472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Formate_CH1O2
type: Species

118786
stoichiometry: 9.0
species: 026287
type: SpeciesReference

140907
stoichiometry: 1.0
species: 043464
type: SpeciesReference

102639
stoichiometry: 1.0
species: 039212
type: SpeciesReference

077049
stoichiometry: 1.0
species: 034014
type: SpeciesReference

052351
stoichiometry: 1.0
species: 040126
type: SpeciesReference

142053
stoichiometry: 1.0
species: 029462
type: SpeciesReference

028728
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: docosa-4,7,10,13,16-pentaenoic acid (n-6)_C22H33O2
type: Species

101686
stoichiometry: 1.0
species: 023211
type: SpeciesReference

047694
stoichiometry: 3.0
species: 044307
type: SpeciesReference

094572
stoichiometry: 1.0
species: 029994
type: SpeciesReference

082793
stoichiometry: 1.0
species: 046635
type: SpeciesReference

126749
stoichiometry: 1.0
species: 039056
type: SpeciesReference

035568
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 8_C79H116N4O64X
type: Species

036812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 14_C143H230N10O114S4X
type: Species

133185
stoichiometry: 2.0
species: 023211
type: SpeciesReference

125664
stoichiometry: 3.0
species: 042548
type: SpeciesReference

125230
stoichiometry: 3.0
species: 024010
type: SpeciesReference

104259
stoichiometry: 1.0
species: 045321
type: SpeciesReference

074951
stoichiometry: 1.0
species: 042548
type: SpeciesReference

072526
stoichiometry: 1.0
species: 042716
type: SpeciesReference

924688
product: 057527
reactant: 057467
reactant: 057479
reactant: 057491
is: http://identifiers.org/ec-code/1.2.1.2
notes: R_FTHFDH subsystem: Folate Metabolism R_FTHFDH equation: [c] : 10fthf + h2o + nadp --> co2 + h + nadph + thf R_FDH subsystem: Fatty Acid Metabolism R_FDH equation: [c] : for + nad --> co2 + nadh
reversible: false
reactant: 057443
is: ENSMMUG00000006581.2
type: Reaction
product: 057539
reactant: 057455
product: 057552
product: 057503
product: 057515
fast: false
is: http://identifiers.org/ec-code/1.5.1.6
is: ENSMMUG00000007630.2

045393
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5
type: Species

925841
name: Fe(III) reduction (ascorbate)
product: 068874
reversible: false
notes: R_FE3R2e subsystem: Heme Biosynthesis R_FE3R2e equation: [e] : ascb-L + (2) fe3 --> dhdascb + (2) fe2 + (2) h
fast: false
is: ENSMMUG00000007295.2
product: 068898
type: Reaction
reactant: 068850
reactant: 068862
product: 068886

062343
stoichiometry: 1.0
species: 032221
type: SpeciesReference

062669
stoichiometry: 1.0
species: 036485
type: SpeciesReference

929673
notes: R_UDPG4E subsystem: Galactose metabolism R_UDPG4E equation: [c] : udpg <==> udpgal R_UAG4E subsystem: Aminosugar Metabolism R_UAG4E equation: [c] : uacgam <==> udpacgal
type: Reaction
reactant: 103693
product: 103717
product: 103705
is: http://identifiers.org/ec-code/5.1.3.2
is: http://identifiers.org/ec-code/5.1.3.7
reversible: true
reactant: 103681
is: ENSMMUG00000019549.2
fast: false

046899
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: omega hydroxy dodecanoate (n-C12:0)_C12H23O3
type: Species

932823
product: 135217
name: glucosaminylphosphatidyl inositol acetyltransferase
type: Reaction
reversible: false
reactant: 135192
product: 135204
notes: R_GPIAT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIAT equation: [c] : gpail_hs + pmtcoa --> coa + gacpail_hs
fast: false
reactant: 135180
is: ENSMMUG00000007923.1

076580
stoichiometry: 1.0
species: 037778
type: SpeciesReference

925192
product: 062512
reactant: 062500
notes: R_PAPStg subsystem: Transport, Golgi Apparatus R_PAPStg equation: paps[c] <==> paps[g]
is: ENSMMUG00000022687.2
fast: false
reversible: true
name: _3'-Phosphoadenylyl sufate Golgi transport
type: Reaction

107076
stoichiometry: 12.0
species: 034179
type: SpeciesReference

023538
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: nLc7Cer_C66H115N4O37FULLRCO
type: Species

062596
stoichiometry: 1.0
species: 039933
type: SpeciesReference

025565
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: ATP_C10H12N5O13P3
type: Species

928734
notes: R_BDMT_U subsystem: N-Glycan Biosynthesis R_BDMT_U equation: [c] : (0.1) chito2pdol_U + gdpmann --> gdp + h + (0.1) mpdol_U R_BDMT_L subsystem: N-Glycan Biosynthesis R_BDMT_L equation: [c] : (0.1) chito2pdol_L + gdpmann --> gdp + h + (0.1) mpdol_L
reactant: 095547
product: 095607
fast: false
is: http://identifiers.org/ec-code/2.4.1.142
product: 095595
reversible: false
reactant: 095559
product: 095583
is: ENSMMUG00000007494.2
product: 095571
reactant: 095535
type: Reaction

136471
stoichiometry: 1.0
species: 034253
type: SpeciesReference

070767
stoichiometry: 1.0
species: 045851
type: SpeciesReference

030237
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dTDPglucose_C16H24N2O16P2
type: Species

147623
stoichiometry: 1.0
species: 040246
type: SpeciesReference

085794
stoichiometry: 4.0
species: 034363
type: SpeciesReference

070333
stoichiometry: 1.0
species: 022123
type: SpeciesReference

120297
stoichiometry: 1.0
species: 044693
type: SpeciesReference

130650
stoichiometry: 3.0
species: 027145
type: SpeciesReference

927341
is: ENSMMUG00000010983.2
reactant: 081443
product: 081467
reactant: 081419
product: 081455
reactant: 081407
reactant: 081431
product: 081479
fast: false
notes: R_METtec subsystem: Transport, Extracellular R_METtec equation: met-L[e] <==> met-L[c] R_ILEtec subsystem: Transport, Extracellular R_ILEtec equation: ile-L[e] <==> ile-L[c] R_LEUtec subsystem: Transport, Extracellular R_LEUtec equation: leu-L[e] <==> leu-L[c] R_VALtec subsystem: Transport, Extracellular R_VALtec equation: val-L[e] <==> val-L[c]
product: 081491
reversible: true
type: Reaction

087014
stoichiometry: 1.0
species: 035265
type: SpeciesReference

021654
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: pentaglutamyl folate (DHF)_C39H43N11O18
type: Species

149530
stoichiometry: 1.0
species: 034363
type: SpeciesReference

060313
stoichiometry: 2.0
species: 040198
type: SpeciesReference

925901
product: 069237
modifier: 069321
is: ENSMMUG00000004188.2
modifier: 069273
modifier: 069261
fast: false
reactant: 069189
product: 069225
modifier: 069345
modifier: 069333
notes: R_FACOAL150 subsystem: Fatty acid activation R_FACOAL150 equation: [c] : atp + coa + ptdca <==> amp + ppi + ptdcacoa R_FACOAL204i subsystem: Fatty acid activation R_FACOAL204i equation: [c] : arachd + atp + coa --> amp + arachdcoa + ppi R_FACOAL170 subsystem: Fatty acid activation R_FACOAL170 equation: [c] : atp + coa + hpdca <==> amp + hpdcacoa + ppi
modifier: 069309
reversible: false
is: http://identifiers.org/ec-code/6.2.1.3
reactant: 069201
reactant: 069213
modifier: 069297
modifier: 069285
product: 069249
type: Reaction

088955
stoichiometry: 1.0
species: 040162
type: SpeciesReference

050094
stoichiometry: 1.0
species: 028098
type: SpeciesReference

092318
stoichiometry: 1.0
species: 045213
type: SpeciesReference

151042
stoichiometry: 1.0
species: 027326
type: SpeciesReference

054377
stoichiometry: 2.0
species: 028364
type: SpeciesReference

105740
stoichiometry: 1.0
species: 021400
type: SpeciesReference

072053
stoichiometry: 1.0
species: 031303
type: SpeciesReference

066558
stoichiometry: 1.0
species: 030381
type: SpeciesReference

147347
stoichiometry: 1.0
species: 038935
type: SpeciesReference

116848
stoichiometry: 1.0
species: 038598
type: SpeciesReference

118281
stoichiometry: 1.0
species: 024525
type: SpeciesReference

114226
stoichiometry: 1.0
species: 037329
type: SpeciesReference

021448
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _4-Trimethylammoniobutanal_C7H16NO
type: Species

045657
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Thymidine_C10H14N2O5
type: Species

120597
stoichiometry: 1.0
species: 026384
type: SpeciesReference

068440
stoichiometry: 18.0
species: 034265
type: SpeciesReference

923668
is: ENSMMUG00000023793.2
fast: false
is: http://identifiers.org/ec-code/2.3.1.65
reactant: 048572
reactant: 048536
product: 048608
product: 048596
reactant: 048560
type: Reaction
product: 048632
product: 048620
reversible: false
reactant: 048584
reactant: 048548
product: 048644
notes: R_BAAT1x subsystem: Bile Acid Biosynthesis R_BAAT1x equation: [x] : cholcoa + gly --> coa + gchola R_BAAT4x subsystem: Bile Acid Biosynthesis R_BAAT4x equation: [x] : dcholcoa + gly --> coa + gdchola R_BAAT2x subsystem: Bile Acid Biosynthesis R_BAAT2x equation: [x] : cholcoa + taur --> coa + tchola R_BAAT3x subsystem: Bile Acid Biosynthesis R_BAAT3x equation: [x] : dgcholcoa + gly --> coa + dgchol R_BAAT5x subsystem: Bile Acid Biosynthesis R_BAAT5x equation: [x] : dcholcoa + taur --> coa + tdchola
product: 048656

095619
stoichiometry: 2.0
species: 041319
type: SpeciesReference

138038
stoichiometry: 1.0
species: 023211
type: SpeciesReference

093089
stoichiometry: 9.0
species: 029030
type: SpeciesReference

129236
stoichiometry: 1.0
species: 029486
type: SpeciesReference

139617
stoichiometry: 1.0
species: 030722
type: SpeciesReference

132329
stoichiometry: 1.0
species: 024949
type: SpeciesReference

124120
stoichiometry: 1.0
species: 043103
type: SpeciesReference

132968
stoichiometry: 1.0
species: 040402
type: SpeciesReference

046476
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: UMP_C9H11N2O9P
type: Species

927834
reactant: 085914
product: 085950
product: 085975
reactant: 085926
fast: false
reactant: 085938
reversible: true
notes: R_THD1m subsystem: NAD Metabolism R_THD1m equation: h[c] + nadh[m] + nadp[m] <==> h[m] + nad[m] + nadph[m]
is: ENSMMUG00000011734.2
type: Reaction
product: 085963
is: http://identifiers.org/ec-code/1.6.1.1
name: NAD(P) transhydrogenase

077725
stoichiometry: 3.0
species: 024250
type: SpeciesReference

021508
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate_C20H31O4
type: Species

082637
stoichiometry: 1.0
species: 040390
type: SpeciesReference

929975
is: http://identifiers.org/ec-code/2.3.1.37
product: 106065
notes: R_ALASm subsystem: Glycine, Serine, and Threonine Metabolism R_ALASm equation: [m] : gly + h + succoa --> 5aop + co2 + coa R_GLYATm subsystem: Glycine, Serine, and Threonine Metabolism R_GLYATm equation: [m] : accoa + gly <==> 2aobut + coa
modifier: 106089
reactant: 106041
modifier: 106101
reactant: 106029
type: Reaction
is: http://identifiers.org/ec-code/2.3.1.29
product: 106077
fast: false
reactant: 106017
modifier: 106125
is: ENSMMUG00000015258.2
reversible: false
is: ENSMMUG00000011944.2
modifier: 106113
product: 106053

027025
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: CMP-N-acetylneuraminate_C20H29N4O16P
type: Species

112017
stoichiometry: 1.0
species: 034363
type: SpeciesReference

033918
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GT1b (homo sapiens)_C77H127N5O46FULLRCO
type: Species

111595
stoichiometry: 1.0
species: 023442
type: SpeciesReference

MODEL1008120001
is described by: http://identifiers.org/pubmed/21051442
species: 026953
reaction: 925408
species: 043584
species: 024937
reaction: 930143
reaction: 926117
reaction: 925817
species: 035157
species: 028134
species: 036764
species: 029247
species: 043054
species: 042175
species: 021582
species: 019361
species: 038188
species: 019852
species: 034303
reaction: 933568
species: 026686
reaction: 929999
species: 031435
reaction: 929431
compartment: 019205
reaction: 924532
species: 021618
species: 022994
species: 021702
species: 033773
reaction: 924040
species: 047225
reaction: 925865
reaction: 925372
species: 029359
species: 043765
species: 038851
species: 041561
species: 031895
species: 045923
reaction: 933351
species: 041102
species: 043127
species: 031290
species: 027314
species: 020678
species: 020398
reaction: 929131
species: 029559
species: 042512
species: 032911
species: 040693
reaction: 929587
species: 044839
reaction: 924688
species: 026759
species: 035109
species: 034051
species: 033203
species: 044234
species: 032221
species: 034581
substance units: 867736
reaction: 934192
reaction: 933892
reaction: 924196
species: 045153
species: 029127
species: 035532
species: 022837
species: 033616
species: 036341
reaction: 931011
species: 044778
species: 019241
species: 031968
species: 031025
species: 033700
species: 025867
species: 024178

109381
stoichiometry: 1.0
species: 021714
type: SpeciesReference

089597
stoichiometry: 1.0
species: 037040
type: SpeciesReference

069249
stoichiometry: 1.0
species: 042548
type: SpeciesReference

930458
reactant: 111161
is: ENSMMUG00000006475.2
reversible: false
product: 111269
is: ENSMMUG00000017167.2
product: 111245
is: http://identifiers.org/ec-code/2.8.2.5
reactant: 111209
is: ENSMMUG00000004201.2
reactant: 111197
product: 111257
product: 111221
type: Reaction
is: ENSMMUG00000017127.2
reactant: 111185
fast: false
notes: R_S4T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T1g equation: [g] : cs_pre + (2) paps --> cs_a,b,e_pre1 + (2) h + (2) pap R_S4T6g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T6g equation: [g] : cs_b_pre4 + paps --> cs_b_pre5 + h + pap R_S4T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T3g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5a + h + pap R_S4T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T2g equation: [g] : cs_a,b_pre3 + paps --> cspg_a + h + pap
product: 111233
reactant: 111173
product: 111281

041175
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Octadecenoyl-CoA (n-C18:1CoA)_C39H64N7O17P3S
type: Species

041489
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2
type: Species

033797
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: GQ1balpha (homo sapiens)_C88H143N6O54FULLRCO
type: Species

103584
stoichiometry: 1.0
species: 022510
type: SpeciesReference

124278
stoichiometry: 1.0
species: 045875
type: SpeciesReference

072379
stoichiometry: 1.0
species: 027121
type: SpeciesReference

123049
stoichiometry: 1.0
species: 046647
type: SpeciesReference

137242
stoichiometry: 1.0
species: 034520
type: SpeciesReference

032112
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: sn-Glycero-3-phosphocholine_C8H20NO6P
type: Species

127588
stoichiometry: 1.0
species: 042331
type: SpeciesReference

928014
product: 087341
is: ENSMMUG00000020049.2
reactant: 087305
is: http://identifiers.org/ec-code/5.4.2.2
is: http://identifiers.org/ec-code/5.4.2.7
product: 087329
fast: false
reactant: 087317
reversible: true
type: Reaction
notes: R_PPM subsystem: Pentose Phosphate Pathway R_PPM equation: [c] : r1p <==> r5p R_PGMT subsystem: Glycolysis/Gluconeogenesis R_PGMT equation: [c] : g1p <==> g6p

097251
stoichiometry: 3.0
species: 040789
type: SpeciesReference

034424
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: H+_H
type: Species

038092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: lignoceryl carnitine_C31H61NO4
type: Species

926345
is: http://identifiers.org/ec-code/1.14.11.18
reactant: 072367
fast: false
name: Phytanoyl-CoA dioxygenase, peroxisomal
reversible: false
type: Reaction
product: 072404
is: ENSMMUG00000023798.2
reactant: 072355
product: 072379
notes: R_PHYHx subsystem: Fatty acid oxidation, peroxisome R_PHYHx equation: [x] : akg + o2 + phytcoa --> co2 + phyt2ohcoa + succ
reactant: 072343
product: 072392

923716
product: 049044
reactant: 049019
product: 049056
reversible: false
product: 049032
reactant: 049007
fast: false
type: Reaction
is: ENSMMUG00000019043.2
is: ENSMMUG00000006634.1
notes: R_ADPRDPm subsystem: Nucleotides R_ADPRDPm equation: [m] : adprib + h2o --> amp + (2) h + r5p
is: http://identifiers.org/ec-code/3.6.1.13
name: ADPribose diphosphatase (mitochondrial)

124712
stoichiometry: 1.0
species: 039655
type: SpeciesReference

090274
stoichiometry: 1.0
species: 038465
type: SpeciesReference

055887
stoichiometry: 1.0
species: 045585
type: SpeciesReference

028944
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _7-Dehydrodesmosterol_C27H42O
type: Species

132678
stoichiometry: 1.0
species: 033263
type: SpeciesReference

037536
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 1_C36H60N3O25X
type: Species

043921
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: sialyl-Tn antigen_C19H30N2O13X
type: Species

021231
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _4-Hydroxyphenylacetate_C8H7O3
type: Species

047827
stoichiometry: 1.0
species: 035920
type: SpeciesReference

079553
stoichiometry: 1.0
species: 025433
type: SpeciesReference

108450
stoichiometry: 1.0
species: 019840
type: SpeciesReference

095078
stoichiometry: 1.0
species: 034363
type: SpeciesReference

042968
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Proline_C5H9NO2
type: Species

094016
stoichiometry: 1.0
species: 047321
type: SpeciesReference

110619
stoichiometry: 1.0
species: 038489
type: SpeciesReference

023780
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
type: Species

105247
stoichiometry: 1.0
species: 034387
type: SpeciesReference

133704
stoichiometry: 1.0
species: 020070
type: SpeciesReference

026384
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Cys-Gly_C5H10N2O3S
type: Species

135084
stoichiometry: 1.0
species: 036017
type: SpeciesReference

036944
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 24_C191H306N13O158S7X
type: Species

073761
stoichiometry: 1.0
species: 026904
type: SpeciesReference

083723
stoichiometry: 1.0
species: 026311
type: SpeciesReference

082201
stoichiometry: 5.0
species: 040102
type: SpeciesReference

934216
name: choline phosphatase
reactant: 149688
product: 149713
product: 149725
type: Reaction
is: ENSMMUG00000005666.2
notes: R_PCHOLP_hs subsystem: Glycerophospholipid Metabolism R_PCHOLP_hs equation: [c] : h2o + pchol_hs --> chol + h + pa_hs
reactant: 149676
reversible: false
is: http://identifiers.org/ec-code/3.1.4.4
fast: false
product: 149701

053134
stoichiometry: 1.0
species: 046235
type: SpeciesReference

116994
stoichiometry: 5.0
species: 025541
type: SpeciesReference

091800
stoichiometry: 1.0
species: 041429
type: SpeciesReference

101554
stoichiometry: 1.0
species: 044533
type: SpeciesReference

923860
fast: false
product: 050082
product: 050034
is: ENSMMUG00000003312.2
reactant: 049961
product: 050142
product: 050070
product: 050106
is: http://identifiers.org/ec-code/2.4.1.175
reactant: 049949
is: ENSMMUG00000013242.2
product: 050046
reactant: 050022
reactant: 049937
product: 050094
product: 050058
is: ENSMMUG00000011819.2
reactant: 049912
reactant: 049997
reactant: 050010
reactant: 049925
notes: R_GLCAT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT5g equation: [g] : cs_e_pre2 + udpglcur --> cs_e_pre3 + h + udp R_GLCAT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT4g equation: [g] : cs_d_pre2 + udpglcur --> cs_d_pre3 + h + udp R_GLCAT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT3g equation: [g] : cs_c,d,e_pre1 + udpglcur --> cs_c_pre2 + h + udp R_GLCAT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT2g equation: [g] : cs_a,b,e_pre1 + udpglcur --> cs_a,b_pre2 + h + udp R_GALNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT5g equation: [g] : cs_e_pre3 + uacgam --> cs_e_pre4 + h + udp R_GALNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT4g equation: [g] : cs_d_pre3 + uacgam --> cs_d_pre4 + h + udp R_GALNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT3g equation: [g] : cs_c_pre2 + uacgam --> cs_c_pre3 + h + udp R_GALNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALNACT2g equation: [g] : cs_a,b_pre2 + uacgam --> cs_a,b_pre3 + h + udp
reactant: 049985
product: 050118
type: Reaction
reversible: false
product: 050130
reactant: 049973

033385
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: (R)-Glycerate_C3H5O4
type: Species

143669
stoichiometry: 1.0
species: 026335
type: SpeciesReference

027566
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: chondroitin sulfate A (GalNAc4S-GlcA), B (IdoA2S-GalNAc4S), and E (GalNAc4,6diS-GlcA), precursor 1_C31H47NO31S2X
type: Species

924952
is: ENSMMUG00000021162.2
is: http://identifiers.org/ec-code/2.7.7.41
fast: false
product: 060215
name: phosphatidate cytidylyltransferase
notes: R_CDS subsystem: Glycerophospholipid Metabolism R_CDS equation: [c] : ctp + h + pa_hs --> cdpdag_hs + ppi
product: 060203
reversible: false
type: Reaction
reactant: 060191
reactant: 060179
reactant: 060167

082080
stoichiometry: 1.0
species: 030078
type: SpeciesReference

934096
reactant: 148650
reactant: 148710
reactant: 148674
product: 148734
reversible: false
product: 148746
product: 148722
fast: false
reactant: 148698
product: 148758
type: Reaction
reactant: 148662
notes: R_SOAT12 subsystem: Cholesterol Metabolism R_SOAT12 equation: [c] : R2coa_hs + chsterol --> coa + xolest_hs R_SOAT12r subsystem: Cholesterol Metabolism R_SOAT12r equation: [r] : R2coa_hs + chsterol --> coa + xolest_hs R_SOAT11r subsystem: Cholesterol Metabolism R_SOAT11r equation: [r] : R1coa_hs + chsterol --> coa + xolest_hs R_SOAT11 subsystem: Cholesterol Metabolism R_SOAT11 equation: [c] : R1coa_hs + chsterol --> coa + xolest_hs
reactant: 148686
is: ENSMMUG00000003768.2

926681
fast: false
is: ENSMMUG00000018336.2
product: 075424
is: http://identifiers.org/ec-code/5.3.3.5
reversible: false
notes: R_EBP2r subsystem: Cholesterol Metabolism R_EBP2r equation: [r] : zymstnl --> lthstrl R_EBP1r subsystem: Cholesterol Metabolism R_EBP1r equation: [r] : zymst --> chlstol
reactant: 075387
type: Reaction
product: 075412
reactant: 075400

116158
stoichiometry: 1.0
species: 046127
type: SpeciesReference

104945
stoichiometry: 1.0
species: 032294
type: SpeciesReference

127897
stoichiometry: 1.0
species: 037693
type: SpeciesReference

097611
stoichiometry: 1.0
species: 046235
type: SpeciesReference

095727
stoichiometry: 1.0
species: 025384
type: SpeciesReference

149289
stoichiometry: 1.0
species: 040246
type: SpeciesReference

123903
stoichiometry: 1.0
species: 030078
type: SpeciesReference

024780
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _2-Aminomuconate 6-semialdehyde_C6H7NO3
type: Species

060613
stoichiometry: 1.0
species: 032524
type: SpeciesReference

056744
stoichiometry: 1.0
species: 027097
type: SpeciesReference

029474
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Dihydrolipoamide_C8H17NOS2
type: Species

151751
stoichiometry: 1.0
species: 034253
type: SpeciesReference

098416
stoichiometry: 1.0
species: 030686
type: SpeciesReference

140086
stoichiometry: 1.0
species: 037172
type: SpeciesReference

040982
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO
type: Species

069139
stoichiometry: 2.0
species: 040029
type: SpeciesReference

079938
stoichiometry: 3.0
species: 034436
type: SpeciesReference

027458
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Carnitine_C7H15NO3
type: Species

027133
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Carbon monoxide_CO
type: Species

051348
stoichiometry: 1.0
species: 027242
type: SpeciesReference

067933
stoichiometry: 1.0
species: 033082
type: SpeciesReference

098620
stoichiometry: 1.0
species: 045285
type: SpeciesReference

134784
stoichiometry: 1.0
species: 025360
type: SpeciesReference

068331
stoichiometry: 1.0
species: 039873
type: SpeciesReference

060240
stoichiometry: 1.0
species: 025360
type: SpeciesReference

103475
stoichiometry: 1.0
species: 029679
type: SpeciesReference

064380
stoichiometry: 2.0
species: 034532
type: SpeciesReference

137399
stoichiometry: 1.0
species: 040150
type: SpeciesReference

138146
stoichiometry: 1.0
species: 020119
type: SpeciesReference

129128
stoichiometry: 2.0
species: 038670
type: SpeciesReference

089488
stoichiometry: 1.0
species: 037548
type: SpeciesReference

052072
stoichiometry: 1.0
species: 043091
type: SpeciesReference

087425
stoichiometry: 1.0
species: 019695
type: SpeciesReference

131158
stoichiometry: 1.0
species: 046331
type: SpeciesReference

045549
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Thiamin triphosphate_C12H16N4O10P3S
type: Species

111486
stoichiometry: 5.0
species: 046307
type: SpeciesReference

037983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Leukotriene C4_C30H45N3O9S
type: Species

024339
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8
type: Species

019421
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _10-Formyltetrahydrofolate_C20H21N7O7
type: Species

042127
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Phenylalanine_C9H11NO2
type: Species

041597
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2
type: Species

019574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _13-cis-retinoyl glucuronide_C26H35O8
type: Species

147239
stoichiometry: 1.0
species: 047369
type: SpeciesReference

019229
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

147816
stoichiometry: 1.0
species: 036017
type: SpeciesReference

055476
stoichiometry: 4.0
species: 034327
type: SpeciesReference

066402
stoichiometry: 1.0
species: 041790
type: SpeciesReference

078984
stoichiometry: 1.0
species: 028497
type: SpeciesReference

119729
stoichiometry: 33.0
species: 027434
type: SpeciesReference

065043
stoichiometry: 1.0
species: 033263
type: SpeciesReference

060505
stoichiometry: 1.0
species: 040246
type: SpeciesReference

029054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: dGDP_C10H12N5O10P2
type: Species

047718
stoichiometry: 12.0
species: 040077
type: SpeciesReference

116268
stoichiometry: 1.0
species: 025130
type: SpeciesReference

080168
stoichiometry: 1.0
species: 043668
type: SpeciesReference

053026
stoichiometry: 3.0
species: 034436
type: SpeciesReference

124821
stoichiometry: 2.0
species: 036185
type: SpeciesReference

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stoichiometry: 1.0
species: 029175
type: SpeciesReference

092799
stoichiometry: 9.0
species: 029042
type: SpeciesReference

141016
stoichiometry: 1.0
species: 025939
type: SpeciesReference

020593
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3-Hydroxy-N6,N6,N6-trimethyl-L-lysine_C9H20N2O3
type: Species

135192
stoichiometry: 1.0
species: 033736
type: SpeciesReference

033493
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]})_C66H111O56X
type: Species

036185
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: potassium_K
type: Species

069959
stoichiometry: 1.0
species: 043006
type: SpeciesReference

096028
stoichiometry: 1.0
species: 046719
type: SpeciesReference

034315
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: H2O_H2O
type: Species

148493
stoichiometry: 1.0
species: 038020
type: SpeciesReference

076206
stoichiometry: 1.0
species: 023333
type: SpeciesReference

027242
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Core 2_C22H37N2O15X
type: Species

091094
stoichiometry: 1.0
species: 036956
type: SpeciesReference

085602
stoichiometry: 1.0
species: 035471
type: SpeciesReference

067207
stoichiometry: 1.0
species: 027242
type: SpeciesReference

031980
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: (alpha-D-Glucosyl)-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C76H127N2O60X
type: Species

060938
stoichiometry: 1.0
species: 034412
type: SpeciesReference

044875
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: D-Tagatose_C6H12O6
type: Species

054098
stoichiometry: 1.0
species: 033749
type: SpeciesReference

095836
stoichiometry: 1.0
species: 020496
type: SpeciesReference

069743
stoichiometry: 1.0
species: 040390
type: SpeciesReference

149398
stoichiometry: 1.0
species: 022752
type: SpeciesReference

031193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2
type: Species

139725
stoichiometry: 2.0
species: 034532
type: SpeciesReference

132521
stoichiometry: 1.0
species: 037742
type: SpeciesReference

104836
stoichiometry: 1.0
species: 038441
type: SpeciesReference

079661
stoichiometry: 3.0
species: 034363
type: SpeciesReference

036245
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 12_C174H279N12O153S9
type: Species

146950
stoichiometry: 1.0
species: 032911
type: SpeciesReference

058059
stoichiometry: 2.0
species: 023162
type: SpeciesReference

129080
stoichiometry: 2.0
species: 038766
type: SpeciesReference

933580
product: 141800
reversible: false
fast: false
is: http://identifiers.org/ec-code/3.5.3.1
type: Reaction
name: arginase
reactant: 141788
product: 141812
reactant: 141776
notes: R_ARGN subsystem: Urea cycle/amino group metabolism R_ARGN equation: [c] : arg-L + h2o --> orn + urea
is: ENSMMUG00000017540.2

136891
stoichiometry: 1.0
species: 045020
type: SpeciesReference

036594
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: keratan sulfate I, degradation product 38_C54H91N3O41
type: Species

041235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: hydroxide ion_HO
type: Species

059157
stoichiometry: 1.0
species: 042427
type: SpeciesReference

046175
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: L-Tyrosine_C9H11NO3
type: Species

043704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Retinoate_C20H27O2
type: Species

141306
stoichiometry: 1.0
species: 031265
type: SpeciesReference

926237
product: 071717
fast: false
is: ENSMMUG00000030296.1
is: http://identifiers.org/ec-code/3.5.1.89
reactant: 071693
type: Reaction
name: N-acetylglucosaminylphosphatidylinositol deacetylase
product: 071705
reversible: false
reactant: 071680
notes: R_ACGPID subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_ACGPID equation: [c] : acgpail_hs + h2o --> ac + gpail_hs

929131
fast: false
product: 099211
reactant: 099187
reactant: 099114
reactant: 099139
reactant: 099127
reactant: 099163
product: 099235
notes: R_PCFLOPm subsystem: Transport, Mitochondrial R_PCFLOPm equation: atp[c] + h2o[c] + pchol_hs[m] --> adp[c] + h[c] + pchol_hs[c] + pi[c] R_PSFLIP subsystem: Transport, Extracellular R_PSFLIP equation: atp[c] + h2o[c] + ps_hs[e] --> adp[c] + h[c] + pi[c] + ps_hs[c] R_PEFLIP subsystem: Transport, Extracellular R_PEFLIP equation: atp[c] + h2o[c] + pe_hs[e] --> adp[c] + h[c] + pe_hs[c] + pi[c] R_PSFLIPm subsystem: Transport, Mitochondrial R_PSFLIPm equation: atp[c] + h2o[c] + ps_hs[c] --> adp[c] + h[c] + pi[c] + ps_hs[m] R_PEFLIPm subsystem: Transport, Mitochondrial R_PEFLIPm equation: atp[c] + h2o[c] + pe_hs[c] --> adp[c] + h[c] + pe_hs[m] + pi[c]
product: 099223
product: 099271
product: 099259
is: ENSMMUG00000017641.2
reactant: 099175
type: Reaction
reversible: false
reactant: 099151
product: 099247
product: 099199
product: 099283

057227
stoichiometry: 6.0
species: 027025
type: SpeciesReference

100602
stoichiometry: 1.0
species: 034412
type: SpeciesReference

083591
stoichiometry: 1.0
species: 031992
type: SpeciesReference

068718
stoichiometry: 1.0
species: 029437
type: SpeciesReference

931981
reversible: false
reactant: 126665
notes: R_GALT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GALT2g equation: [g] : lxser + udpgal --> h + l2xser + udp
product: 126701
product: 126677
reactant: 126652
product: 126689
name: UDP-D-galactose:galactosylxylose galactosyltransferase, Golgi apparatus
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.134
fast: false
is: ENSMMUG00000019519.2

031580
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: D-Fructose_C6H12O6
type: Species

105632
stoichiometry: 5.0
species: 045585
type: SpeciesReference

063947
stoichiometry: 1.0
species: 023235
type: SpeciesReference

149422
stoichiometry: 1.0
species: 034363
type: SpeciesReference

026650
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Cholesterol_C27H46O
type: Species

107136
stoichiometry: 1.0
species: 021026
type: SpeciesReference

147515
stoichiometry: 2.0
species: 034412
type: SpeciesReference

926117
type: Reaction
product: 070901
is: http://identifiers.org/ec-code/1.17.4.1
reactant: 070851
product: 070863
reactant: 070839
product: 070888
product: 070875
reversible: false
reactant: 070827
notes: R_RNDR1 subsystem: Nucleotides R_RNDR1 equation: [c] : adp + trdrd --> dadp + h2o + trdox R_RNDR3 subsystem: Nucleotides R_RNDR3 equation: [c] : cdp + trdrd --> dcdp + h2o + trdox R_RNDR2 subsystem: Nucleotides R_RNDR2 equation: [c] : gdp + trdrd --> dgdp + h2o + trdox R_RNDR4 subsystem: Nucleotides R_RNDR4 equation: [c] : trdrd + udp --> dudp + h2o + trdox
product: 070914
reactant: 070815
product: 070927
fast: false
is: ENSMMUG00000003962.2
reactant: 070803
is: ENSMMUG00000002057.2

120141
stoichiometry: 1.0
species: 043307
type: SpeciesReference

135941
stoichiometry: 1.0
species: 034253
type: SpeciesReference

068138
stoichiometry: 2.0
species: 046019
type: SpeciesReference

032536
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: D-Glucosamine_C6H14NO5
type: Species

066161
stoichiometry: 1.0
species: 034253
type: SpeciesReference

142801
stoichiometry: 2.0
species: 024853
type: SpeciesReference

086048
stoichiometry: 1.0
species: 034412
type: SpeciesReference

068065
stoichiometry: 1.0
species: 044717
type: SpeciesReference

053736
stoichiometry: 2.0
species: 041766
type: SpeciesReference

924892
reactant: 059278
reactant: 058965
reactant: 059121
type: Reaction
reactant: 059061
reactant: 059314
reactant: 059218
product: 059448
product: 059521
product: 059726
reactant: 059206
is: ENSMMUG00000007606.2
product: 059702
product: 059424
reactant: 059097
product: 059436
product: 059777
reactant: 059290
product: 059690
product: 059641
reactant: 059254
product: 059654
product: 059605
product: 059569
product: 059497
reactant: 059242
product: 059751
reactant: 059193
product: 059581
reversible: false
reactant: 059145
product: 059593
reactant: 059169
reactant: 059364
product: 059400
reactant: 059133
reactant: 059157
product: 059509
reactant: 059230
product: 059533
product: 059738
reactant: 059339
product: 059376
product: 059388
product: 059764
product: 059629
reactant: 059049
product: 059714
fast: false
reactant: 058989
reactant: 059181
product: 059666
product: 059460
product: 059678
product: 059472
product: 059617
reactant: 059109
reactant: 059327
reactant: 059013
reactant: 059037
reactant: 059302
reactant: 059001
notes: R_HEXCCPT2 subsystem: Carnitine shuttle R_HEXCCPT2 equation: [m] : coa + hexccrn --> crn + hexccoa R_C181CPT2 subsystem: Carnitine shuttle R_C181CPT2 equation: [m] : coa + odecrn --> crn + odecoa R_C160CPT2 subsystem: Carnitine shuttle R_C160CPT2 equation: [m] : coa + pmtcrn --> crn + pmtcoa R_RTOTALCRNCPT2 subsystem: Carnitine shuttle R_RTOTALCRNCPT2 equation: [m] : Rtotalcrn + coa --> Rtotalcoa + crn R_RTOTAL2CRNCPT2 subsystem: Carnitine shuttle R_RTOTAL2CRNCPT2 equation: [m] : Rtotal2crn + coa --> Rtotal2coa + crn R_VACCCPT2 subsystem: Carnitine shuttle R_VACCCPT2 equation: [m] : coa + vacccrn --> crn + vacccoa R_EICOSTETCPT2 subsystem: Carnitine shuttle R_EICOSTETCPT2 equation: [m] : coa + eicostetcrn --> crn + eicostetcoa R_TTDCPT2 subsystem: Carnitine shuttle R_TTDCPT2 equation: [m] : coa + ttdcrn --> crn + tdcoa R_PTDCACRNCPT2 subsystem: Carnitine shuttle R_PTDCACRNCPT2 equation: [m] : coa + ptdcacrn --> crn + ptdcacoa R_LGNCCPT2 subsystem: Carnitine shuttle R_LGNCCPT2 equation: [m] : coa + lgnccrn --> crn + lgnccoa R_C226CPT2 subsystem: Carnitine shuttle R_C226CPT2 equation: [m] : c226crn + coa --> c226coa + crn R_C161CPT22 subsystem: Carnitine shuttle R_C161CPT22 equation: [m] : coa + hdd2crn --> crn + hdd2coa R_DLNLCGCPT2 subsystem: Carnitine shuttle R_DLNLCGCPT2 equation: [m] : coa + dlnlcgcrn --> crn + dlnlcgcoa R_LNLCCPT2 subsystem: Carnitine shuttle R_LNLCCPT2 equation: [m] : coa + lnlccrn --> crn + lnlccoa R_CLPNDCPT2 subsystem: Carnitine shuttle R_CLPNDCPT2 equation: [m] : clpndcrn + coa --> clpndcoa + crn R_DCSPTN1CPT2 subsystem: Carnitine shuttle R_DCSPTN1CPT2 equation: [m] : coa + dcsptn1crn --> crn + dcsptn1coa R_HPDCACRNCPT2 subsystem: Carnitine shuttle R_HPDCACRNCPT2 equation: [m] : coa + hpdcacrn --> crn + hpdcacoa R_LNELDCCPT2 subsystem: Carnitine shuttle R_LNELDCCPT2 equation: [m] : coa + lneldccrn --> crn + lneldccoa R_STRDNCCPT2 subsystem: Carnitine shuttle R_STRDNCCPT2 equation: [m] : coa + strdnccrn --> crn + strdnccoa R_NRVNCCPT2 subsys…
reactant: 059025
reactant: 059266
product: 059412
reactant: 059085
reactant: 058977
product: 059545
reactant: 059351
product: 059557
product: 059485
reactant: 059073

114515
stoichiometry: 1.0
species: 043380
type: SpeciesReference

142536
stoichiometry: 1.0
species: 025276
type: SpeciesReference

049092
stoichiometry: 1.0
species: 041802
type: SpeciesReference

933796
fast: false
is: ENSMMUG00000019327.2
reversible: true
product: 143993
notes: R_HCO3_NAt subsystem: Transport, Extracellular R_HCO3_NAt equation: hco3[e] + na1[e] <==> hco3[c] + na1[c]
is: ENSMMUG00000015605.2
type: Reaction
name: bicarbonate transport (Na/HCO3 cotransport)
reactant: 143957
product: 143981
reactant: 143969

932931
reversible: false
reactant: 135941
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_SULFOX subsystem: Cysteine Metabolism R_SULFOX equation: (2) ficytC[m] + h2o[c] + so3[c] --> (2) focytC[m] + (2) h[c] + so4[c] R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
is: http://identifiers.org/ec-code/3.2.1.113
reactant: 135843
reactant: 135867
product: 136097
product: 135977
product: 136073
product: 136025
product: 136013
product: 135989
is: http://identifiers.org/ec-code/1.8.3.1
is: ENSMMUG00000013304.2
product: 135965
product: 135953
reactant: 135929
product: 136061
product: 136001
product: 136085
reactant: 135903
type: Reaction
reactant: 135831
reactant: 135855
reactant: 135818
reactant: 135794
reactant: 135782
reactant: 135916
reactant: 135891
product: 136049
fast: false
product: 136037
reactant: 135879
reactant: 135806

106944
stoichiometry: 1.0
species: 025130
type: SpeciesReference

118895
stoichiometry: 1.0
species: 024731
type: SpeciesReference

065981
stoichiometry: 1.0
species: 021123
type: SpeciesReference

136001
stoichiometry: 1.0
species: 038839
type: SpeciesReference

926453
product: 073250
product: 073166
is: ENSMMUG00000020762.2
is: http://identifiers.org/ec-code/3.5.1.12
product: 073214
notes: R_BTND1 subsystem: Biotin Metabolism R_BTND1 equation: [c] : biocyt + h2o --> btn + lys-L R_BTND1n subsystem: Biotin Metabolism R_BTND1n equation: [n] : biocyt + h2o --> btn + lys-L R_BTNDe subsystem: Biotin Metabolism R_BTNDe equation: [e] : biocyt + h2o --> btn + lys-L R_BTNDm subsystem: Biotin Metabolism R_BTNDm equation: [m] : biocyt + h2o --> btn + lys-L
reactant: 073142
reversible: false
product: 073178
reactant: 073154
type: Reaction
reactant: 073106
product: 073190
reactant: 073130
reactant: 073070
product: 073226
reactant: 073118
fast: false
reactant: 073082
product: 073202
product: 073238
reactant: 073094

139303
stoichiometry: 1.0
species: 039402
type: SpeciesReference

137676
stoichiometry: 1.0
species: 044742
type: SpeciesReference

925084
product: 061742
type: Reaction
reactant: 061730
reversible: false
fast: false
is: ENSMMUG00000009713.2
product: 061754
notes: R_ACGSm subsystem: Urea cycle/amino group metabolism R_ACGSm equation: [m] : accoa + glu-L --> acglu + coa + h
reactant: 061718
is: http://identifiers.org/ec-code/2.3.1.1
name: N-acteylglutamate synthase, mitochondrial
product: 061766

107280
stoichiometry: 1.0
species: 040306
type: SpeciesReference

086194
stoichiometry: 5.0
species: 041970
type: SpeciesReference

928122
product: 088318
fast: false
reactant: 088257
notes: R_34HPPOR subsystem: Tyrosine metabolism R_34HPPOR equation: [c] : 34hpp + o2 --> co2 + hgentis R_PPOR subsystem: Phenylalanine metabolism R_PPOR equation: [c] : o2 + phpyr --> 2hyoxplac + co2
type: Reaction
product: 088306
product: 088294
reactant: 088281
is: http://identifiers.org/ec-code/1.13.11.27
reversible: false
is: ENSMMUG00000016454.2
reactant: 088269

134279
stoichiometry: 1.0
species: 040547
type: SpeciesReference

056418
stoichiometry: 2.0
species: 020167
type: SpeciesReference

031834
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Type IIIH glycolipid_C70H122N3O40FULLRCO
type: Species

071861
stoichiometry: 1.0
species: 033529
type: SpeciesReference

022800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S
type: Species

130419
stoichiometry: 1.0
species: 042043
type: SpeciesReference

144065
stoichiometry: 1.0
species: 028315
type: SpeciesReference

132738
stoichiometry: 1.0
species: 035860
type: SpeciesReference

108899
stoichiometry: 1.0
species: 021775
type: SpeciesReference

096237
stoichiometry: 1.0
species: 043211
type: SpeciesReference

048464
stoichiometry: 1.0
species: 023211
type: SpeciesReference

131919
stoichiometry: 1.0
species: 032258
type: SpeciesReference

048115
stoichiometry: 1.0
species: 035375
type: SpeciesReference

076869
stoichiometry: 2.0
species: 024525
type: SpeciesReference

119305
stoichiometry: 4.0
species: 046199
type: SpeciesReference

058795
stoichiometry: 1.0
species: 040644
type: SpeciesReference

106836
stoichiometry: 1.0
species: 046127
type: SpeciesReference

058602
stoichiometry: 1.0
species: 025541
type: SpeciesReference

127476
stoichiometry: 1.0
species: 029199
type: SpeciesReference

034869
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Histidine_C6H9N3O2
type: Species

092751
stoichiometry: 7.0
species: 030309
type: SpeciesReference

078283
stoichiometry: 1.0
species: 046079
type: SpeciesReference

130540
stoichiometry: 2.0
species: 034253
type: SpeciesReference

123879
stoichiometry: 1.0
species: 026518
type: SpeciesReference

125387
stoichiometry: 1.0
species: 043392
type: SpeciesReference

151451
stoichiometry: 1.0
species: 045621
type: SpeciesReference

117776
stoichiometry: 2.0
species: 030710
type: SpeciesReference

060469
stoichiometry: 1.0
species: 034412
type: SpeciesReference

930738
is: http://identifiers.org/ec-code/2.4.1.1
reversible: false
product: 114419
is: ENSMMUG00000022604.2
is: ENSMMUG00000009199.2
reactant: 114371
product: 114407
type: Reaction
product: 114383
product: 114395
is: ENSMMUG00000014670.2
fast: false
reactant: 114359
reactant: 114335
notes: R_GLPASE2 subsystem: Starch and Sucrose Metabolism R_GLPASE2 equation: [c] : glygn3 + (7) h2o --> Tyr-ggn + (7) glc-D R_GLPASE1 subsystem: Starch and Sucrose Metabolism R_GLPASE1 equation: [c] : glygn2 + (3) pi --> dxtrn + (3) g1p
reactant: 114347

091788
stoichiometry: 1.0
species: 025577
type: SpeciesReference

026674
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Cholesterol_C27H46O
type: Species

927942
type: Reaction
name: glycine N-methyltransferase
reactant: 086859
product: 086883
product: 086909
is: http://identifiers.org/ec-code/2.1.1.20
reversible: false
fast: false
is: ENSMMUG00000001393.2
notes: R_GNMT subsystem: Glycine, Serine, and Threonine Metabolism R_GNMT equation: [c] : amet + gly --> ahcys + h + sarcs
reactant: 086871
product: 086896

047585
stoichiometry: 1.0
species: 033408
type: SpeciesReference

035677
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Hypotaurine_C2H6NO2S
type: Species

048536
stoichiometry: 2.0
species: 026530
type: SpeciesReference

134387
stoichiometry: 1.0
species: 034253
type: SpeciesReference

133076
stoichiometry: 1.0
species: 020082
type: SpeciesReference

035205
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 19_C43H67N2O42S2
type: Species

115748
stoichiometry: 1.0
species: 019433
type: SpeciesReference

101795
stoichiometry: 3.0
species: 034363
type: SpeciesReference

114911
stoichiometry: 1.0
species: 036317
type: SpeciesReference

112682
stoichiometry: 23.0
species: 034363
type: SpeciesReference

042548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Diphosphate_HO7P2
type: Species

094681
stoichiometry: 2.0
species: 031919
type: SpeciesReference

097671
stoichiometry: 1.0
species: 034375
type: SpeciesReference

108972
stoichiometry: 1.0
species: 043440
type: SpeciesReference

078561
stoichiometry: 2.0
species: 034412
type: SpeciesReference

151391
stoichiometry: 1.0
species: 023138
type: SpeciesReference

053170
stoichiometry: 1.0
species: 026323
type: SpeciesReference

924532
product: 056478
reactant: 056442
fast: false
product: 056466
is: http://identifiers.org/ec-code/2.3.1.7
is: ENSMMUG00000010787.2
reversible: true
type: Reaction
reactant: 056454
notes: R_CSNAT2x subsystem: Fatty Acid Metabolism R_CSNAT2x equation: [x] : crn + dmnoncoa <==> coa + dmnoncrn
name: carnitine dimethyl nonanoyl transferase, revsible, peroxisomal

071148
stoichiometry: 1.0
species: 031786
type: SpeciesReference

100914
stoichiometry: 1.0
species: 036197
type: SpeciesReference

072634
stoichiometry: 2.0
species: 023211
type: SpeciesReference

930179
reversible: true
product: 107895
is: ENSMMUG00000029371.1
product: 107907
reactant: 107859
notes: R_PROSTGF2t subsystem: Transport, Extracellular R_PROSTGF2t equation: prostgf2[e] <==> prostgf2[c] R_SRTNtu subsystem: Transport, Extracellular R_SRTNtu equation: srtn[e] <==> srtn[c] R_PROSTGE2t2 subsystem: Transport, Extracellular R_PROSTGE2t2 equation: prostge2[e] <==> prostge2[c]
reactant: 107871
reactant: 107847
is: ENSMMUG00000015662.2
product: 107883
fast: false
type: Reaction

121308
stoichiometry: 4.0
species: 025541
type: SpeciesReference

105307
stoichiometry: 2.0
species: 046187
type: SpeciesReference

132437
stoichiometry: 1.0
species: 046343
type: SpeciesReference

025819
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Biliverdin_C33H32N4O6
type: Species

121452
stoichiometry: 1.0
species: 034327
type: SpeciesReference

141716
stoichiometry: 1.0
species: 043777
type: SpeciesReference

065609
stoichiometry: 1.0
species: 037426
type: SpeciesReference

103885
stoichiometry: 1.0
species: 034363
type: SpeciesReference

933495
is: http://identifiers.org/ec-code/3.1.3.18
type: Reaction
product: 141378
is: ENSMMUG00000019234.2
product: 141366
reactant: 141342
name: Phosphoglycolate phosphatase
fast: false
notes: R_PGLYCP subsystem: Glyoxylate and Dicarboxylate Metabolism R_PGLYCP equation: [c] : 2pglyc + h2o --> glyclt + pi
reversible: false
reactant: 141354

112128
stoichiometry: 1.0
species: 039571
type: SpeciesReference

135337
stoichiometry: 1.0
species: 026844
type: SpeciesReference

023647
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Acetylcholine_C7H16NO2
type: Species

092354
stoichiometry: 1.0
species: 041211
type: SpeciesReference

096040
stoichiometry: 2.0
species: 046379
type: SpeciesReference

931225
product: 120645
product: 120621
reactant: 120585
is: http://identifiers.org/ec-code/3.4.11.2
reactant: 120561
reactant: 120597
type: Reaction
product: 120609
is: ENSMMUG00000014983.2
notes: R_AMPTASECGe subsystem: Glutathione Metabolism R_AMPTASECGe equation: [e] : cgly + h2o --> cys-L + gly R_AMPTASECG subsystem: Glutathione Metabolism R_AMPTASECG equation: [c] : cgly + h2o --> cys-L + gly
fast: false
product: 120633
reactant: 120573
reversible: false

087353
stoichiometry: 1.0
species: 019852
type: SpeciesReference

074855
stoichiometry: 1.0
species: 029873
type: SpeciesReference

113609
stoichiometry: 1.0
species: 024070
type: SpeciesReference

096383
stoichiometry: 2.0
species: 034363
type: SpeciesReference

076761
stoichiometry: 1.0
species: 041754
type: SpeciesReference

931011
reactant: 117716
product: 117740
notes: R_PI3PP subsystem: Inositol Phosphate Metabolism R_PI3PP equation: [c] : h2o + pail3p_hs --> pail_hs + pi R_PI35P3P subsystem: Inositol Phosphate Metabolism R_PI35P3P equation: [c] : h2o + pail35p_hs --> pail5p_hs + pi
reactant: 117728
type: Reaction
reactant: 117704
reversible: false
is: ENSMMUG00000022236.2
product: 117764
product: 117752
fast: false

148153
stoichiometry: 1.0
species: 044935
type: SpeciesReference

933568
reactant: 141728
is: ENSMMUG00000004617.2
fast: false
type: Reaction
reversible: true
reactant: 141740
name: glutathione peroxidase (e)
product: 141764
is: http://identifiers.org/ec-code/1.11.1.9
notes: R_GTHPe subsystem: Glutathione Metabolism R_GTHPe equation: [e] : (2) gthrd + h2o2 <==> gthox + (2) h2o
product: 141752

110354
stoichiometry: 4.0
species: 034253
type: SpeciesReference

132016
stoichiometry: 1.0
species: 036836
type: SpeciesReference

080192
stoichiometry: 1.0
species: 043620
type: SpeciesReference

078417
stoichiometry: 1.0
species: 035507
type: SpeciesReference

136435
stoichiometry: 1.0
species: 022196
type: SpeciesReference

062006
stoichiometry: 1.0
species: 040282
type: SpeciesReference

108643
stoichiometry: 1.0
species: 019524
type: SpeciesReference

151247
stoichiometry: 1.0
species: 023695
type: SpeciesReference

123481
stoichiometry: 1.0
species: 024634
type: SpeciesReference

133281
stoichiometry: 1.0
species: 042379
type: SpeciesReference

021316
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: _4-Methylpentanal_C6H12O
type: Species

095427
stoichiometry: 1.0
species: 020629
type: SpeciesReference

931585
product: 123541
reactant: 123481
notes: R_DPROOp subsystem: Arginine and Proline Metabolism R_DPROOp equation: [x] : o2 + pro-D --> 1p2cbxl + h + h2o2 R_DALAOXx subsystem: D-alanine metabolism R_DALAOXx equation: [x] : ala-D + h2o + o2 --> h2o2 + nh4 + pyr R_DARGOp subsystem: D-arg and D-orn metabolism R_DARGOp equation: [x] : arg-D + h2o + o2 --> 5g2oxpt + h2o2 + nh4 R_DORNOp subsystem: D-arg and D-orn metabolism R_DORNOp equation: [x] : h2o + o2 + orn-D --> 5a2opntn + h2o2 + nh4
product: 123517
product: 123529
product: 123578
reversible: false
reactant: 123493
product: 123590
reactant: 123445
product: 123553
fast: false
reactant: 123469
reactant: 123457
is: ENSMMUG00000006893.2
type: Reaction
product: 123566
reactant: 123505
is: http://identifiers.org/ec-code/1.4.3.3

060215
stoichiometry: 1.0
species: 042548
type: SpeciesReference

149107
stoichiometry: 1.0
species: 039523
type: SpeciesReference

119535
stoichiometry: 1.0
species: 028740
type: SpeciesReference

128570
stoichiometry: 1.0
species: 046199
type: SpeciesReference

925805
reactant: 068126
notes: R_SUCCt2m subsystem: Transport, Mitochondrial R_SUCCt2m equation: pi[m] + succ[c] <==> pi[c] + succ[m] R_MALSO4tm subsystem: Transport, Mitochondrial R_MALSO4tm equation: mal-L[c] + so4[m] <==> mal-L[m] + so4[c] R_FUMTSULtm subsystem: Transport, Mitochondrial R_FUMTSULtm equation: fum[c] + tsul[m] <==> fum[m] + tsul[c] R_FUMSO3tm subsystem: Transport, Mitochondrial R_FUMSO3tm equation: fum[c] + so3[m] <==> fum[m] + so3[c] R_MALSO3tm subsystem: Transport, Mitochondrial R_MALSO3tm equation: mal-L[c] + so3[m] <==> mal-L[m] + so3[c] R_MALTSULtm subsystem: Transport, Mitochondrial R_MALTSULtm equation: mal-L[c] + tsul[m] <==> mal-L[m] + tsul[c] R_FUMSO4tm subsystem: Transport, Mitochondrial R_FUMSO4tm equation: fum[c] + so4[m] <==> fum[m] + so4[c] R_FUMtm subsystem: Transport, Mitochondrial R_FUMtm equation: fum[c] + pi[m] <==> fum[m] + pi[c] R_MALtm subsystem: Transport, Mitochondrial R_MALtm equation: mal-L[c] + pi[m] <==> mal-L[m] + pi[c]
product: 068186
product: 068150
reactant: 068065
product: 068210
is: ENSMMUG00000004457.2
type: Reaction
reactant: 068114
fast: false
product: 068174
reversible: true
product: 068198
reactant: 068053
product: 068162
reactant: 068101
product: 068138
reactant: 068077
reactant: 068089

092606
stoichiometry: 1.0
species: 040741
type: SpeciesReference

117378
stoichiometry: 2.0
species: 034387
type: SpeciesReference

098008
stoichiometry: 1.0
species: 042283
type: SpeciesReference

081226
stoichiometry: 1.0
species: 047381
type: SpeciesReference

128425
stoichiometry: 1.0
species: 040270
type: SpeciesReference

111041
stoichiometry: 1.0
species: 030139
type: SpeciesReference

084530
stoichiometry: 1.0
species: 044681
type: SpeciesReference

148457
stoichiometry: 1.0
species: 029115
type: SpeciesReference

151006
stoichiometry: 1.0
species: 026626
type: SpeciesReference

101397
stoichiometry: 1.0
species: 040270
type: SpeciesReference

934516
type: Reaction
product: 152029
name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
product: 152017
notes: R_PHETHPTOX2 subsystem: Tyr, Phe, Trp Biosynthesis R_PHETHPTOX2 equation: [c] : o2 + phe-L + thbpt --> thbpt4acam + tyr-L
reactant: 151980
reactant: 151992
reactant: 152004
is: http://identifiers.org/ec-code/1.14.16.1
is: ENSMMUG00000011908.2
fast: false
reversible: false

086871
stoichiometry: 1.0
species: 024792
type: SpeciesReference

035411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: heparan sulfate, precursor 10_C79H121N5O77S4X
type: Species

131086
stoichiometry: 1.0
species: 046476
type: SpeciesReference

030599
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: ecgonine methyl ester_C10H17NO3
type: Species

061190
stoichiometry: 6.0
species: 024853
type: SpeciesReference

037996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Leukotriene C4_C30H45N3O9S
type: Species

098332
stoichiometry: 1.0
species: 024226
type: SpeciesReference

133832
stoichiometry: 2.0
species: 046403
type: SpeciesReference

108317
stoichiometry: 1.0
species: 036113
type: SpeciesReference

087992
stoichiometry: 1.0
species: 022437
type: SpeciesReference

150077
stoichiometry: 1.0
species: 034290
type: SpeciesReference

929527
is: ENSMMUG00000017830.2
product: 102675
reactant: 102663
reversible: false
reactant: 102651
name: deoxyguanosine kinase
is: http://identifiers.org/ec-code/2.7.1.113
product: 102699
notes: R_DGNSKm subsystem: Nucleotides R_DGNSKm equation: [m] : atp + dgsn --> adp + dgmp + h
product: 102687
type: Reaction
fast: false

924328
product: 054365
product: 054341
reactant: 054257
reactant: 054305
product: 054329
product: 054389
product: 054377
reversible: false
product: 054317
fast: false
type: Reaction
reactant: 054269
reactant: 054233
reactant: 054281
product: 054353
is: ENSMMUG00000008685.2
reactant: 054245
notes: R_THMDt5 subsystem: Transport, Extracellular R_THMDt5 equation: (2) na1[e] + thymd[e] --> (2) na1[c] + thymd[c] R_CYTDt4 subsystem: Transport, Extracellular R_CYTDt4 equation: cytd[e] + na1[e] --> cytd[c] + na1[c] R_URIt5 subsystem: Transport, Extracellular R_URIt5 equation: (2) na1[e] + uri[e] --> (2) na1[c] + uri[c] R_GSNt5 subsystem: Transport, Extracellular R_GSNt5 equation: gsn[e] + (2) na1[e] --> gsn[c] + (2) na1[c] R_CYTDt5 subsystem: Transport, Extracellular R_CYTDt5 equation: cytd[e] + (2) na1[e] --> cytd[c] + (2) na1[c] R_INSt5 subsystem: Transport, Extracellular R_INSt5 equation: ins[e] + (2) na1[e] --> ins[c] + (2) na1[c] R_ADNt4 subsystem: Transport, Extracellular R_ADNt4 equation: adn[e] + na1[e] --> adn[c] + na1[c] R_URIt4 subsystem: Transport, Extracellular R_URIt4 equation: na1[e] + uri[e] --> na1[c] + uri[c] R_THMDt4 subsystem: Transport, Extracellular R_THMDt4 equation: na1[e] + thymd[e] --> na1[c] + thymd[c] R_INSt4 subsystem: Transport, Extracellular R_INSt4 equation: ins[e] + na1[e] --> ins[c] + na1[c] R_GSNt4 subsystem: Transport, Extracellular R_GSNt4 equation: gsn[e] + na1[e] --> gsn[c] + na1[c] R_ADNt5 subsystem: Transport, Extracellular R_ADNt5 equation: adn[e] + (2) na1[e] --> adn[c] + (2) na1[c]
reactant: 054293

073359
stoichiometry: 1.0
species: 038068
type: SpeciesReference

119645
stoichiometry: 1.0
species: 034665
type: SpeciesReference

142150
stoichiometry: 1.0
species: 045465
type: SpeciesReference

059738
stoichiometry: 1.0
species: 038369
type: SpeciesReference

029909
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Dolichol diphosphate, human liver homolog_C1080H1758O70P20
type: Species

099935
stoichiometry: 1.0
species: 037790
type: SpeciesReference

040729
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: nervonyl coenzyme A_C45H76N7O17P3S
type: Species

032572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: globoside (homo sapiens)_C44H79N2O22FULLRCO
type: Species

140775
stoichiometry: 1.0
species: 037742
type: SpeciesReference

083446
stoichiometry: 1.0
species: 025915
type: SpeciesReference

141197
stoichiometry: 1.0
species: 037898
type: SpeciesReference

094475
stoichiometry: 1.0
species: 041150
type: SpeciesReference

094548
stoichiometry: 1.0
species: 039008
type: SpeciesReference

042644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6
type: Species

145589
stoichiometry: 1.0
species: 036679
type: SpeciesReference

028800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dCTP_C9H12N3O13P3
type: Species

114671
stoichiometry: 1.0
species: 036365
type: SpeciesReference

107389
stoichiometry: 1.0
species: 046343
type: SpeciesReference

934408
name: coproporphyrinogen oxidase (O2 required)
reactant: 151054
product: 151103
product: 151078
is: ENSMMUG00000010833.2
product: 151090
notes: R_CPPPGO subsystem: Heme Biosynthesis R_CPPPGO equation: [c] : cpppg3 + (2) h + o2 --> (2) co2 + (2) h2o + pppg9
reactant: 151042
reactant: 151066
fast: false
reversible: false
is: http://identifiers.org/ec-code/1.3.3.3
type: Reaction

076435
stoichiometry: 2.0
species: 031387
type: SpeciesReference

059842
stoichiometry: 4.0
species: 034363
type: SpeciesReference

124435
stoichiometry: 2.0
species: 021171
type: SpeciesReference

088173
stoichiometry: 2.0
species: 034436
type: SpeciesReference

023235
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Acetyl-CoA_C23H34N7O17P3S
type: Species

075290
stoichiometry: 1.0
species: 035411
type: SpeciesReference

056153
stoichiometry: 1.0
species: 045573
type: SpeciesReference

053892
stoichiometry: 3.0
species: 034387
type: SpeciesReference

143453
stoichiometry: 1.0
species: 035121
type: SpeciesReference

072950
stoichiometry: 1.0
species: 032234
type: SpeciesReference

142680
stoichiometry: 1.0
species: 043692
type: SpeciesReference

126099
stoichiometry: 1.0
species: 034327
type: SpeciesReference

082068
stoichiometry: 1.0
species: 034881
type: SpeciesReference

096594
stoichiometry: 2.0
species: 031665
type: SpeciesReference

058096
stoichiometry: 1.0
species: 025637
type: SpeciesReference

058361
stoichiometry: 1.0
species: 040921
type: SpeciesReference

052339
stoichiometry: 1.0
species: 040246
type: SpeciesReference

030698
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Elaidic carnitine_C25H47NO4
type: Species

068271
stoichiometry: 1.0
species: 033155
type: SpeciesReference

112430
stoichiometry: 1.0
species: 037790
type: SpeciesReference

148601
stoichiometry: 6.0
species: 040029
type: SpeciesReference

025009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Anthranilate_C7H6NO2
type: Species

045105
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S
type: Species

105343
stoichiometry: 1.0
species: 040330
type: SpeciesReference

931849
product: 125760
reactant: 125700
product: 125785
product: 125772
reactant: 125688
product: 125797
reversible: true
is: ENSMMUG00000006792.2
product: 125809
reactant: 125724
notes: R_S4TASE2ly subsystem: Chondroitin sulfate degradation R_S4TASE2ly equation: [l] : cs_a_deg3 + h2o <==> cs_a_deg4 + h + so4 R_S4TASE3ly subsystem: Chondroitin sulfate degradation R_S4TASE3ly equation: [l] : cs_b + h2o <==> cs_b_deg1 + h + so4 R_S4TASE1ly subsystem: Chondroitin sulfate degradation R_S4TASE1ly equation: [l] : cs_a + h2o <==> cs_a_deg1 + h + so4 R_S4TASE5ly subsystem: Chondroitin sulfate degradation R_S4TASE5ly equation: [l] : cs_e_deg4 + h2o <==> cs_e_deg5 + h + so4 R_S4TASE4ly subsystem: Chondroitin sulfate degradation R_S4TASE4ly equation: [l] : cs_e + h2o <==> cs_e_deg1 + h + so4
product: 125821
product: 125748
is: http://identifiers.org/ec-code/3.1.6.12
reactant: 125712
type: Reaction
fast: false
reactant: 125676
reactant: 125736

928566
is: http://identifiers.org/ec-code/1.14.19.1
reversible: false
notes: R_DESAT18_3 subsystem: Fatty acid elongation R_DESAT18_3 equation: [c] : h + nadh + o2 + stcoa --> (2) h2o + nad + odecoa R_DESAT18_5 subsystem: Fatty acid elongation R_DESAT18_5 equation: [c] : h + nadh + o2 + stcoa --> (2) h2o + nad + od2coa R_DESAT16_2 subsystem: Fatty acid elongation R_DESAT16_2 equation: [c] : h + nadh + o2 + pmtcoa --> (2) h2o + hdcoa + nad R_DESAT18_4 subsystem: Fatty acid elongation R_DESAT18_4 equation: [c] : h + nadh + o2 + stcoa --> (2) h2o + nad + vacccoa
reactant: 094415
product: 094475
reactant: 094391
product: 094487
reactant: 094427
fast: false
is: ENSMMUG00000010817.2
type: Reaction
product: 094451
product: 094439
product: 094463
product: 094499
reactant: 094379
reactant: 094403

925492
product: 065717
product: 065609
product: 065525
reactant: 065272
reactant: 065336
reactant: 065362
reactant: 065259
is: http://identifiers.org/ec-code/2.4.1.149
product: 065501
product: 065561
product: 065669
product: 065645
is: ENSMMUG00000014347.2
reactant: 065349
reactant: 065323
is: ENSMMUG00000001110.2
product: 065705
reactant: 065310
is: ENSMMUG00000011777.1
product: 065681
reactant: 065375
reactant: 065452
reactant: 065388
reversible: false
notes: R_AG13T6g subsystem: Keratan sulfate biosynthesis R_AG13T6g equation: [g] : ksi_pre6 + uacgam --> h + ksi_pre7 + udp R_AG13T17g subsystem: Keratan sulfate biosynthesis R_AG13T17g equation: [g] : ksii_core4_pre4 + uacgam --> h + ksii_core4_pre5 + udp R_AG13T2g subsystem: Keratan sulfate biosynthesis R_AG13T2g equation: [g] : ksii_core2_pre4 + uacgam --> h + ksii_core2_pre5 + udp R_AG13T5g subsystem: Keratan sulfate biosynthesis R_AG13T5g equation: [g] : ksi_pre3 + uacgam --> h + ksi_pre4 + udp R_AG13T8g subsystem: Keratan sulfate biosynthesis R_AG13T8g equation: [g] : ksi_pre12 + uacgam --> h + ksi_pre13 + udp R_AG13T12g subsystem: Keratan sulfate biosynthesis R_AG13T12g equation: [g] : ksi_pre24 + uacgam --> h + ksi_pre25 + udp R_AG13T1g subsystem: Keratan sulfate biosynthesis R_AG13T1g equation: [g] : ksii_core2_pre2 + uacgam --> h + ksii_core2_pre3 + udp R_AG13T10g subsystem: Keratan sulfate biosynthesis R_AG13T10g equation: [g] : ksi_pre18 + uacgam --> h + ksi_pre19 + udp R_AG13T14g subsystem: Keratan sulfate biosynthesis R_AG13T14g equation: [g] : ksi_pre30 + uacgam --> h + ksi_pre31 + udp R_AG13T13g subsystem: Keratan sulfate biosynthesis R_AG13T13g equation: [g] : ksi_pre27 + uacgam --> h + ksi_pre28 + udp R_AG13T9g subsystem: Keratan sulfate biosynthesis R_AG13T9g equation: [g] : ksi_pre15 + uacgam --> h + ksi_pre16 + udp R_AG13T15g subsystem: Keratan sulfate biosynthesis R_AG13T15g equation: [g] : ksi_pre33 + uacgam --> h + ksi_pre34 + udp R_AG13T4g subsystem: Keratan sulfate biosynthesis R_AG13T4g equation: [g] : ksi_pre1 + uacgam --> h + ksi_pre2 + udp R_AG13T11g subsystem: Keratan sulfate biosynthesis R_AG13T11g equation: [g] : ksi_pre21 + uacgam --> h + ksi_pre22 + udp R_AG13T16g subsystem: Keratan sulfate biosynthesis R_AG13T16g equation: [g] : ksii_core4_pre2 + uacgam --> h + ksii_core4_pre3 + udp R_AG13T18g subsystem: Keratan sulfate biosynthesis R_AG13T18g equation: [g] : ksii_core4_pre7 + uacgam --> h + ksii_core4_pre8 + udp R_AG13T7g subsystem: Ker…
is: ENSMMUG00000012654.2
product: 065657
reactant: 065414
reactant: 065439
product: 065549
reactant: 065247
reactant: 065401
product: 065633
product: 065537
product: 065693
reactant: 065284
product: 065585
reactant: 065427
product: 065621
reactant: 065297
product: 065513
reactant: 065464
product: 065573
product: 065597
reactant: 065476
type: Reaction
is: ENSMMUG00000015992.2
fast: false
product: 065488

112658
stoichiometry: 1.0
species: 037729
type: SpeciesReference

129524
stoichiometry: 2.0
species: 042572
type: SpeciesReference

031750
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)3 (Cer)1_C90H155N4O54FULLRCO
type: Species

144401
stoichiometry: 1.0
species: 045345
type: SpeciesReference

122701
stoichiometry: 1.0
species: 044983
type: SpeciesReference

079118
stoichiometry: 1.0
species: 042548
type: SpeciesReference

051878
stoichiometry: 1.0
species: 024010
type: SpeciesReference

926657
name: GlcNAc N-deacetylase / N-sulfotransferase
fast: false
product: 075278
product: 075266
is: ENSMMUG00000015259.2
reactant: 075242
is: ENSMMUG00000005414.2
reactant: 075230
is: ENSMMUG00000022976.2
type: Reaction
product: 075290
product: 075254
reactant: 075217
notes: R_GLCNACDASg subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACDASg equation: [g] : (4) h2o + hs_pre9 + (4) paps --> (4) ac + (4) h + hs_pre10 + (4) pap
reversible: false
is: ENSMMUG00000002883.2

068754
stoichiometry: 1.0
species: 022027
type: SpeciesReference

052978
stoichiometry: 1.0
species: 041573
type: SpeciesReference

925612
notes: R_PLA2_2 subsystem: Glycerophospholipid Metabolism R_PLA2_2 equation: [c] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
is: http://identifiers.org/ec-code/3.1.1.4
product: 066450
reversible: false
fast: false
name: phospholipase A2
reactant: 066414
reactant: 066402
is: ENSMMUG00000002701.2
product: 066426
type: Reaction
product: 066438

146744
stoichiometry: 2.0
species: 031025
type: SpeciesReference

132774
stoichiometry: 1.0
species: 020726
type: SpeciesReference

024755
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: S-aminomethyldihydrolipoamide_C9H21N2OS2
type: Species

102923
stoichiometry: 1.0
species: 041778
type: SpeciesReference

119874
stoichiometry: 1.0
species: 038044
type: SpeciesReference

104970
stoichiometry: 1.0
species: 031907
type: SpeciesReference

020155
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _2-Phosphoglycolate_C2H2O6P
type: Species

094113
stoichiometry: 1.0
species: 025541
type: SpeciesReference

037560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 3_C55H89N5O38X
type: Species

084265
stoichiometry: 1.0
species: 031181
type: SpeciesReference

077821
stoichiometry: 3.0
species: 030090
type: SpeciesReference

934048
notes: R_TCHOLAt2 subsystem: Transport, Extracellular R_TCHOLAt2 equation: (2) na1[e] + tchola[e] --> (2) na1[c] + tchola[c] R_GCHOLAt2 subsystem: Transport, Extracellular R_GCHOLAt2 equation: gchola[e] + (2) na1[e] --> gchola[c] + (2) na1[c] R_CHOLATEt2 subsystem: Transport, Extracellular R_CHOLATEt2 equation: cholate[e] + (2) na1[e] --> cholate[c] + (2) na1[c]
fast: false
is: ENSMMUG00000007664.2
type: Reaction
product: 148190
product: 148165
reversible: false
reactant: 148129
product: 148177
product: 148153
reactant: 148117
reactant: 148105
reactant: 148141

089222
stoichiometry: 1.0
species: 036353
type: SpeciesReference

116558
stoichiometry: 1.0
species: 045621
type: SpeciesReference

119766
stoichiometry: 1.0
species: 034785
type: SpeciesReference

083169
stoichiometry: 1.0
species: 034253
type: SpeciesReference

131388
stoichiometry: 1.0
species: 045417
type: SpeciesReference

087655
stoichiometry: 8.0
species: 041754
type: SpeciesReference

089694
stoichiometry: 1.0
species: 037426
type: SpeciesReference

064235
stoichiometry: 2.0
species: 024598
type: SpeciesReference

129548
stoichiometry: 1.0
species: 026614
type: SpeciesReference

037341
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate II biosynthesis, precursor 1_C33H53N3O23X
type: Species

106980
stoichiometry: 1.0
species: 021219
type: SpeciesReference

111414
stoichiometry: 1.0
species: 024853
type: SpeciesReference

098898
stoichiometry: 1.0
species: 043319
type: SpeciesReference

129693
stoichiometry: 3.0
species: 024574
type: SpeciesReference

102771
stoichiometry: 1.0
species: 042007
type: SpeciesReference

068730
stoichiometry: 1.0
species: 019265
type: SpeciesReference

933267
product: 138554
reactant: 138542
notes: R_ACONTm subsystem: Citric Acid Cycle R_ACONTm equation: [m] : cit <==> icit
is: ENSMMUG00000001454.2
is: http://identifiers.org/ec-code/4.2.1.3
fast: false
reversible: true
name: Aconitate hydratase
type: Reaction

144618
stoichiometry: 1.0
species: 038068
type: SpeciesReference

081503
stoichiometry: 1.0
species: 024094
type: SpeciesReference

045923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: L-Tryptophan_C11H12N2O2
type: Species

047033
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: _7 alpha-Hydroxycholesterol_C27H46O2
type: Species

121884
stoichiometry: 1.0
species: 040126
type: SpeciesReference

109369
stoichiometry: 1.0
species: 025541
type: SpeciesReference

032959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: D-Glucose_C6H12O6
type: Species

071825
stoichiometry: 1.0
species: 033505
type: SpeciesReference

027205
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Coenzyme A_C21H32N7O16P3S
type: Species

027747
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1_C31H47NO31S2X
type: Species

116293
stoichiometry: 1.0
species: 039981
type: SpeciesReference

022135
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019217
name: _6-Pyruvoyl-5,6,7,8-tetrahydropterin_C9H11N5O3
type: Species

109093
stoichiometry: 1.0
species: 037717
type: SpeciesReference

105451
stoichiometry: 30.0
species: 040029
type: SpeciesReference

927089
product: 078741
fast: false
reactant: 078717
is: ENSMMUG00000011148.2
type: Reaction
name: Ubiquinone biosynthesis monooxgenase COQ6
reactant: 078729
notes: R_COQ6m subsystem: Ubiquinone Biosynthesis R_COQ6m equation: [m] : 2dp6mep + o2 --> 2dp6mobq + h2o
product: 078753
reversible: false

117920
stoichiometry: 1.0
species: 033433
type: SpeciesReference

033359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Glycerol 3-phosphate_C3H7O6P
type: Species

093835
stoichiometry: 1.0
species: 043392
type: SpeciesReference

930570
product: 112382
is: http://identifiers.org/ec-code/2.7.1.21
fast: false
notes: R_TMDK1 subsystem: Nucleotides R_TMDK1 equation: [c] : atp + thymd --> adp + dtmp + h R_DURIK1 subsystem: Nucleotides R_DURIK1 equation: [c] : atp + duri --> adp + dump + h
is: ENSMMUG00000021867.2
product: 112394
reactant: 112357
type: Reaction
product: 112370
reactant: 112333
reactant: 112345
reversible: false
product: 112406

056950
stoichiometry: 1.0
species: 025541
type: SpeciesReference

057251
stoichiometry: 1.0
species: 033809
type: SpeciesReference

043054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Prostaglandin D2_C20H31O5
type: Species

050275
stoichiometry: 1.0
species: 025215
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species: 045887
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species: 046803
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species: 027759
type: SpeciesReference

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species: 034363
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species: 027833
type: SpeciesReference

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type: SpeciesReference

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species: 034303
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has only substance units: false
initial concentration: NaN
initial amount: NaN
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species: 030637
type: SpeciesReference

146853
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species: 030418
type: SpeciesReference

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species: 040270
type: SpeciesReference

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stoichiometry: 2.0
species: 038815
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: keratan sulfate I, degradation product 15_C160H257N11O140S8
type: Species

063754
stoichiometry: 2.0
species: 043476
type: SpeciesReference

050625
stoichiometry: 1.0
species: 038887
type: SpeciesReference

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stoichiometry: 1.0
species: 038706
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Fucose 1-phosphate_C6H11O8P
type: Species

104680
stoichiometry: 2.0
species: 040813
type: SpeciesReference

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name: trimethyllysine dioxygenase
fast: false
is: http://identifiers.org/ec-code/1.14.11.8
reactant: 099042
reversible: false
product: 099078
reactant: 099066
product: 099090
type: Reaction
product: 099102
notes: R_TMLYSOX subsystem: Lysine Metabolism R_TMLYSOX equation: [c] : akg + o2 + tmlys --> 3htmelys + co2 + succ
is: ENSMMUG00000009481.2
reactant: 099054

138374
stoichiometry: 1.0
species: 046211
type: SpeciesReference

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stoichiometry: 1.0
species: 043476
type: SpeciesReference

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stoichiometry: 1.0
species: 028303
type: SpeciesReference

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stoichiometry: 1.0
species: 027097
type: SpeciesReference

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stoichiometry: 1.0
species: 027109
type: SpeciesReference

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stoichiometry: 1.0
species: 033736
type: SpeciesReference

145479
stoichiometry: 1.0
species: 036449
type: SpeciesReference

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stoichiometry: 8.0
species: 034387
type: SpeciesReference

073010
stoichiometry: 1.0
species: 026444
type: SpeciesReference

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stoichiometry: 1.0
species: 046791
type: SpeciesReference

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stoichiometry: 1.0
species: 043054
type: SpeciesReference

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stoichiometry: 1.0
species: 046307
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4
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stoichiometry: 1.0
species: 040270
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: naphthalene epoxide_C10H8O
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136133
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species: 040632
type: SpeciesReference

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species: 033628
type: SpeciesReference

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species: 024010
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species: 020690
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species: 027181
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species: 027181
type: SpeciesReference

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initial concentration: NaN
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name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 4_C31H49NO29S
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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name: L-3-Amino-isobutanoate_C4H9NO2
type: Species

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species: 037329
type: SpeciesReference

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stoichiometry: 1.0
species: 040849
type: SpeciesReference

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boundary condition: false
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initial concentration: NaN
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name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2
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146131
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species: 034387
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species: 040789
type: SpeciesReference

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species: 028050
type: SpeciesReference

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species: 034436
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species: 044597
type: SpeciesReference

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species: 030599
type: SpeciesReference

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species: 043981
type: SpeciesReference

039450
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: (R)-Mevalonate_C6H11O4
type: Species

088510
stoichiometry: 2.0
species: 034253
type: SpeciesReference

097215
stoichiometry: 1.0
species: 039225
type: SpeciesReference

069971
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species: 021255
type: SpeciesReference

049949
stoichiometry: 4.0
species: 046199
type: SpeciesReference

077930
stoichiometry: 2.0
species: 034315
type: SpeciesReference

055223
stoichiometry: 1.0
species: 043464
type: SpeciesReference

077073
stoichiometry: 1.0
species: 026384
type: SpeciesReference

132882
stoichiometry: 2.0
species: 026977
type: SpeciesReference

126737
stoichiometry: 2.0
species: 034253
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product: 079577
reactant: 079407
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product: 079565
type: Reaction
product: 079541
product: 079481
is: ENSMMUG00000012331.2
reactant: 079443
product: 079529
product: 079517
reactant: 079394
fast: false
product: 079589
product: 079553
reactant: 079431
reactant: 079346
reactant: 079334
reactant: 079358
reversible: false
reactant: 079322
reactant: 079456
product: 079505
reactant: 079382
reactant: 079370
product: 079469
reactant: 079419
product: 079493
product: 079601

114093
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species: 037645
type: SpeciesReference

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stoichiometry: 1.0
species: 036968
type: SpeciesReference

089331
stoichiometry: 1.0
species: 036980
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019229
name: Oxalate_C2O4
type: Species

131497
stoichiometry: 1.0
species: 037548
type: SpeciesReference

069562
stoichiometry: 1.0
species: 035387
type: SpeciesReference

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stoichiometry: 2.0
species: 034520
type: SpeciesReference

121776
stoichiometry: 1.0
species: 022885
type: SpeciesReference

112224
stoichiometry: 1.0
species: 045465
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: cholesterol ester_C27H45XCO2
type: Species

102663
stoichiometry: 1.0
species: 025565
type: SpeciesReference

067909
stoichiometry: 1.0
species: 024646
type: SpeciesReference

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stoichiometry: 1.0
species: 046755
type: SpeciesReference

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reactant: 051252
is: http://identifiers.org/ec-code/1.1.1.37
is: ENSMMUG00000003198.2
product: 051312
product: 051288
is: http://identifiers.org/ec-code/1.1.1.272
product: 051300
product: 051276
reactant: 051264
reactant: 051240
type: Reaction
fast: false
notes: R_MDHm subsystem: Citric Acid Cycle R_MDHm equation: [m] : mal-L + nad <==> h + nadh + oaa R_SLDxm subsystem: Cysteine Metabolism R_SLDxm equation: [m] : nad + sl-L <==> 3spyr + h + nadh
reversible: true

930608
fast: false
is: ENSMMUG00000004553.2
product: 112971
type: Reaction
notes: R_UDPGALtg subsystem: Transport, Golgi Apparatus R_UDPGALtg equation: udpgal[c] + ump[g] <==> udpgal[g] + ump[c] R_UGALNACtg subsystem: Transport, Golgi Apparatus R_UGALNACtg equation: udpacgal[c] + ump[g] <==> udpacgal[g] + ump[c]
reactant: 112935
product: 112983
product: 112959
reactant: 112923
reversible: true
reactant: 112947

927605
reactant: 083543
type: Reaction
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is: ENSMMUG00000020046.2
reactant: 083531
reversible: false
product: 083567
reactant: 083507
product: 083579
product: 083603
reactant: 083519
fast: false
product: 083591
product: 083555

079226
stoichiometry: 2.0
species: 031181
type: SpeciesReference

933159
fast: false
notes: R_PTRCAT1 subsystem: Arginine and Proline Metabolism R_PTRCAT1 equation: [c] : accoa + ptrc --> aprut + coa + h
reactant: 138050
product: 138062
is: ENSMMUG00000013511.2
name: Putrescine acetyltransferase
product: 138074
is: ENSMMUG00000008335.2
product: 138086
reactant: 138038
reversible: false
type: Reaction
is: http://identifiers.org/ec-code/2.3.1.57

081659
stoichiometry: 2.0
species: 025565
type: SpeciesReference

069417
stoichiometry: 3.0
species: 040017
type: SpeciesReference

122243
stoichiometry: 1.0
species: 046235
type: SpeciesReference

074747
stoichiometry: 1.0
species: 034363
type: SpeciesReference

055111
stoichiometry: 12.0
species: 034253
type: SpeciesReference

085914
stoichiometry: 1.0
species: 040222
type: SpeciesReference

056841
stoichiometry: 2.0
species: 034363
type: SpeciesReference

106404
stoichiometry: 1.0
species: 034363
type: SpeciesReference

057697
stoichiometry: 1.0
species: 043897
type: SpeciesReference

036908
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: keratan sulfate I biosynthesis, precursor 21_C177H284N12O145S6X
type: Species

096150
stoichiometry: 1.0
species: 040222
type: SpeciesReference

074507
stoichiometry: 8.0
species: 026832
type: SpeciesReference

129043
stoichiometry: 1.0
species: 038694
type: SpeciesReference

116402
stoichiometry: 1.0
species: 035762
type: SpeciesReference

026518
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Cholate_C24H39O5
type: Species

124989
stoichiometry: 1.0
species: 042283
type: SpeciesReference

111727
stoichiometry: 1.0
species: 047201
type: SpeciesReference

095932
stoichiometry: 1.0
species: 043103
type: SpeciesReference

150548
stoichiometry: 1.0
species: 041465
type: SpeciesReference

045213
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: tetracosapentaenoyl carnitine_C31H51NO4
type: Species

043307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: pendtadenoyl carnitine_C22H43NO4
type: Species

108534
stoichiometry: 1.0
species: 025154
type: SpeciesReference

098224
stoichiometry: 8.0
species: 027073
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: Formate_CH1O2
type: Species

112370
stoichiometry: 1.0
species: 030381
type: SpeciesReference

933039
reactant: 137338
reactant: 137326
fast: false
reactant: 137350
product: 137374
is: http://identifiers.org/ec-code/1.5.99.8
is: ENSMMUG00000030814.1
product: 137387
type: Reaction
is: ENSMMUG00000019749.2
notes: R_PRO1x subsystem: Arginine and Proline Metabolism R_PRO1x equation: [c] : nad + pro-L --> 1pyr5c + (2) h + nadh R_PROD2 subsystem: Arginine and Proline Metabolism R_PROD2 equation: [c] : fad + pro-L --> 1pyr5c + fadh2 + h
reversible: false
is: http://identifiers.org/ec-code/1.5.1.2
product: 137362
product: 137399

063971
stoichiometry: 1.0
species: 042524
type: SpeciesReference

047297
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: XTP_C10H11N4O15P3
type: Species

076652
stoichiometry: 1.0
species: 044742
type: SpeciesReference

038947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: monoacylglycerol 2 (homo sapiens)_C3H7O2FULLR2CO2
type: Species

103013
stoichiometry: 1.0
species: 046235
type: SpeciesReference

924100
reactant: 052243
product: 052351
is: ENSMMUG00000013499.2
notes: R_HSD3B3r subsystem: Steroid Metabolism R_HSD3B3r equation: [r] : eandrstrn + h + nadph --> andrstandn + h2o + nadp R_HSD3B2r subsystem: Steroid Metabolism R_HSD3B2r equation: [r] : eandrstrn + h + nadh --> andrstandn + h2o + nad R_HSD3B11r subsystem: Steroid Metabolism R_HSD3B11r equation: [r] : nad + prgnlone --> h + nadh + prgstrn R_HSD3B12r subsystem: Steroid Metabolism R_HSD3B12r equation: [r] : dhea + nad --> andrstndn + h + nadh R_HSD3B13r subsystem: Steroid Metabolism R_HSD3B13r equation: [r] : 17ahprgnlone + nad --> 17ahprgstrn + h + nadh
reactant: 052255
product: 052339
product: 052375
product: 052363
reactant: 052279
product: 052303
reactant: 052267
product: 052291
is: ENSMMUG00000007545.2
reactant: 052207
reversible: false
fast: false
reactant: 052219
product: 052387
product: 052315
type: Reaction
product: 052327
reactant: 052231
reactant: 052194
is: ENSMMUG00000019847.2
is: ENSMMUG00000003702.2

084687
stoichiometry: 1.0
species: 020786
type: SpeciesReference

024477
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: _1-alkyl 2-lysoglycerol 3-phosphocholine_C10H21O5NPFULLR
type: Species

931693
is: ENSMMUG00000006000.2
modifier: 124604
modifier: 124544
reactant: 124374
is: http://identifiers.org/ec-code/2.6.1.5
reversible: false
modifier: 124508
reactant: 124398
is: ENSMMUG00000019316.2
modifier: 124484
is: http://identifiers.org/ec-code/2.6.1.58
modifier: 124592
product: 124447
modifier: 124520
modifier: 124496
product: 124435
reactant: 124362
notes: R_EHGLAT2m subsystem: Arginine and Proline Metabolism R_EHGLAT2m equation: [m] : e4hglu + oaa --> 4h2oglt + asp-L R_TYRTAm subsystem: Tyrosine metabolism R_TYRTAm equation: [m] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1m subsystem: Phenylalanine metabolism R_PHETA1m equation: [m] : akg + phe-L <==> glu-L + phpyr R_LCYSTATm subsystem: Cysteine Metabolism R_LCYSTATm equation: [m] : Lcyst + akg <==> 3spyr + glu-L R_CYSTAm subsystem: Cysteine Metabolism R_CYSTAm equation: [m] : akg + cys-L <==> glu-L + mercppyr R_ASPTAm subsystem: Alanine and Aspartate Metabolism R_ASPTAm equation: [m] : akg + asp-L <==> glu-L + oaa R_EHGLATm subsystem: Arginine and Proline Metabolism R_EHGLATm equation: [m] : akg + e4hglu --> 4h2oglt + glu-L R_3SALATAim subsystem: Cysteine Metabolism R_3SALATAim equation: [m] : 3sala + akg + h --> 3snpyr + glu-L
type: Reaction
product: 124422
reactant: 124410
modifier: 124556
reactant: 124386
is: http://identifiers.org/ec-code/2.6.1.21
is: http://identifiers.org/ec-code/2.6.1.1
modifier: 124472
modifier: 124580
is: http://identifiers.org/ec-code/2.6.1.3
is: ENSMMUG00000008258.2
product: 124459
modifier: 124568
modifier: 124532
fast: false

077497
stoichiometry: 1.0
species: 037729
type: SpeciesReference

060107
stoichiometry: 1.0
species: 040547
type: SpeciesReference

151355
stoichiometry: 1.0
species: 025360
type: SpeciesReference

030381
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: dUMP_C9H11N2O8P
type: Species

044428
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

045068
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S
type: Species

120922
stoichiometry: 1.0
species: 032536
type: SpeciesReference

108426
stoichiometry: 1.0
species: 025505
type: SpeciesReference

035302
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: heparan sulfate, degradation product 2_C79H116N5O96S10
type: Species

146311
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species: 041465
type: SpeciesReference

135613
stoichiometry: 2.0
species: 040029
type: SpeciesReference

113007
stoichiometry: 1.0
species: 032875
type: SpeciesReference

137966
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species: 030406
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _1-Pyrroline-5-carboxylate_C5H6NO2
type: Species

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stoichiometry: 3.0
species: 033311
type: SpeciesReference

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stoichiometry: 1.0
species: 032972
type: SpeciesReference

148045
stoichiometry: 1.0
species: 034363
type: SpeciesReference

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stoichiometry: 1.0
species: 040474
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: propionyl-carnitine_C10H19NO4
type: Species

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stoichiometry: 7.0
species: 030454
type: SpeciesReference

127379
stoichiometry: 1.0
species: 027446
type: SpeciesReference

103183
stoichiometry: 1.0
species: 021014
type: SpeciesReference

092462
stoichiometry: 1.0
species: 026047
type: SpeciesReference

038622
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)_C49H88NO29PFULLRCO2FULLR2CO2
type: Species

115043
stoichiometry: 1.0
species: 036715
type: SpeciesReference

025855
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: Biocytin_C16H28N4O4S
type: Species

132980
stoichiometry: 2.0
species: 040029
type: SpeciesReference

079093
stoichiometry: 1.0
species: 024853
type: SpeciesReference

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stoichiometry: 1.0
species: 039164
type: SpeciesReference

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stoichiometry: 4.0
species: 040017
type: SpeciesReference

100032
stoichiometry: 1.0
species: 037766
type: SpeciesReference

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stoichiometry: 1.0
species: 023066
type: SpeciesReference

130528
stoichiometry: 1.0
species: 028836
type: SpeciesReference

107498
stoichiometry: 1.0
species: 022462
type: SpeciesReference

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boundary condition: false
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initial amount: NaN
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species: 041163
type: SpeciesReference

141860
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species: 032911
type: SpeciesReference

113115
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species: 039993
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144824
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species: 041030
type: SpeciesReference

061082
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species: 041054
type: SpeciesReference

121271
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species: 030066
type: SpeciesReference

034881
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Histamine_C5H10N3
type: Species

064477
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species: 034363
type: SpeciesReference

042752
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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boundary condition: false
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initial concentration: NaN
initial amount: NaN
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142572
stoichiometry: 1.0
species: 034363
type: SpeciesReference

080058
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species: 026432
type: SpeciesReference

098116
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species: 042115
type: SpeciesReference

123061
stoichiometry: 1.0
species: 047093
type: SpeciesReference

129946
stoichiometry: 1.0
species: 025915
type: SpeciesReference

078874
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species: 024853
type: SpeciesReference

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S
type: Species

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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: Dehydroepiandrosterone sulfate_C19H27O5S
type: Species

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stoichiometry: 1.0
species: 025541
type: SpeciesReference

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stoichiometry: 35.0
species: 034448
type: SpeciesReference

148758
stoichiometry: 2.0
species: 047177
type: SpeciesReference

086290
stoichiometry: 1.0
species: 043909
type: SpeciesReference

025118
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
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name: _20alpha-Hydroxyprogesterone_C21H32O2
type: Species

078717
stoichiometry: 1.0
species: 019937
type: SpeciesReference

120068
stoichiometry: 1.0
species: 022837
type: SpeciesReference

068162
stoichiometry: 4.0
species: 039008
type: SpeciesReference

066137
stoichiometry: 1.0
species: 033021
type: SpeciesReference

021871
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _5-Methylthio-5-deoxy-D-ribose 1-phosphate_C6H11O7PS
type: Species

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product: 093582
is: ENSMMUG00000006310.2
product: 093618
fast: false
notes: R_AMY1e subsystem: Starch and Sucrose Metabolism R_AMY1e equation: [e] : (8) h2o + strch1 --> (8) glc-D + strch2 R_CYSTSERex subsystem: Transport, Extracellular R_CYSTSERex equation: Lcystin[e] + ser-L[c] --> Lcystin[c] + ser-L[e] R_AMY2e subsystem: Starch and Sucrose Metabolism R_AMY2e equation: [e] : glygn2 + (8) h2o --> (8) glc-D + glygn4 R_SERLYSNaex subsystem: Transport, Extracellular R_SERLYSNaex equation: lys-L[c] + na1[e] + ser-L[e] --> lys-L[e] + na1[c] + ser-L[c]
reactant: 093510
product: 093630
product: 093606
reactant: 093534
reactant: 093486
product: 093643
product: 093570
reactant: 093522
reactant: 093474
reactant: 093462
product: 093594
reactant: 093546
reactant: 093498
type: Reaction
reversible: false
product: 093558
is: http://identifiers.org/ec-code/3.2.1.1

058470
stoichiometry: 5.0
species: 034412
type: SpeciesReference

031025
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: Ethanolamine phosphate_C2H7NO4P
type: Species

039667
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _1D-myo-Inositol 4-phosphate_C6H11O9P
type: Species

043392
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Pyridoxal 5'-phosphate_C8H8NO6P
type: Species

931957
is: http://identifiers.org/ec-code/4.4.1.1
reactant: 126532
product: 126544
reversible: false
type: Reaction
product: 126556
reactant: 126520
reactant: 126508
product: 126568
product: 126580
fast: false
notes: R_SELCYSTGL subsystem: Selenoamino acid metabolism R_SELCYSTGL equation: [c] : h2o + selcyst --> 2obut + nh4 + selcys R_CYSTGL subsystem: Cysteine Metabolism R_CYSTGL equation: [c] : cyst-L + h2o --> 2obut + cys-L + nh4
is: ENSMMUG00000019326.2

924436
product: 055331
reactant: 055137
reactant: 055211
product: 055343
reactant: 055186
product: 055271
reactant: 055223
reversible: true
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_ACACt2 subsystem: Transport, Extracellular R_ACACt2 equation: acac[e] + h[e] <==> acac[c] + h[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_PYRt2p subsystem: D-alanine metabolism R_PYRt2p equation: h[c] + pyr[c] <==> h[x] + pyr[x] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c]
type: Reaction
reactant: 055150
fast: false
product: 055307
product: 055247
product: 055259
reactant: 055198
reactant: 055162
reactant: 055235
product: 055319
product: 055283
is: ENSMMUG00000014368.2
reactant: 055174
product: 055295

030273
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dTMP_C10H13N2O8P
type: Species

056454
stoichiometry: 1.0
species: 027482
type: SpeciesReference

050915
stoichiometry: 1.0
species: 034363
type: SpeciesReference

102061
stoichiometry: 1.0
species: 046235
type: SpeciesReference

044283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Sulfate_O4S
type: Species

143237
stoichiometry: 1.0
species: 035399
type: SpeciesReference

125121
stoichiometry: 1.0
species: 040438
type: SpeciesReference

055331
stoichiometry: 6.0
species: 034363
type: SpeciesReference

023370
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019192
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO
type: Species

066870
stoichiometry: 1.0
species: 025360
type: SpeciesReference

105235
stoichiometry: 1.0
species: 034277
type: SpeciesReference

119983
stoichiometry: 1.0
species: 045213
type: SpeciesReference

079541
stoichiometry: 1.0
species: 025360
type: SpeciesReference

138218
stoichiometry: 1.0
species: 038104
type: SpeciesReference

047839
stoichiometry: 1.0
species: 021763
type: SpeciesReference

106197
stoichiometry: 2.0
species: 040306
type: SpeciesReference

121992
stoichiometry: 1.0
species: 033420
type: SpeciesReference

028956
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: debrisoquine_C10H14N3
type: Species

145697
stoichiometry: 2.0
species: 036473
type: SpeciesReference

095860
stoichiometry: 1.0
species: 034339
type: SpeciesReference

111885
stoichiometry: 1.0
species: 029235
type: SpeciesReference

055899
stoichiometry: 1.0
species: 033034
type: SpeciesReference

134592
stoichiometry: 1.0
species: 022800
type: SpeciesReference

033203
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO
type: Species

081875
stoichiometry: 1.0
species: 034399
type: SpeciesReference

047995
stoichiometry: 1.0
species: 037693
type: SpeciesReference

029692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
name: dihomo-gamma-linolenyl coenzyme A_C41H64N7O17P3S
type: Species

928002
is: ENSMMUG00000018354.2
fast: false
product: 087293
is: ENSMMUG00000030331.1
reactant: 087281
is: http://identifiers.org/ec-code/5.3.99.3
type: Reaction
name: Prostaglandin E synthase
notes: R_PGESr subsystem: Eicosanoid Metabolism R_PGESr equation: [r] : prostgh2 <==> prostge2
reversible: true
is: ENSMMUG00000018258.2

026371
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Cys-Gly_C5H10N2O3S
type: Species

038080
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: lignoceryl carnitine_C31H61NO4
type: Species

076327
stoichiometry: 1.0
species: 024034
type: SpeciesReference

125954
stoichiometry: 2.0
species: 040861
type: SpeciesReference

024190
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: adrenyl coenzyme A_C43H66N7O17P3S
type: Species

097647
stoichiometry: 2.0
species: 039152
type: SpeciesReference

103705
stoichiometry: 1.0
species: 046379
type: SpeciesReference

104535
stoichiometry: 1.0
species: 023962
type: SpeciesReference

095715
stoichiometry: 1.0
species: 026808
type: SpeciesReference

139543
stoichiometry: 1.0
species: 030710
type: SpeciesReference

149277
stoichiometry: 1.0
species: 034327
type: SpeciesReference

060649
stoichiometry: 1.0
species: 032124
type: SpeciesReference

132666
stoichiometry: 1.0
species: 026844
type: SpeciesReference

924988
type: Reaction
product: 060457
reversible: true
reactant: 060433
reactant: 060445
product: 060481
is: http://identifiers.org/ec-code/1.1.1.30
notes: R_BDHm subsystem: Butanoate Metabolism R_BDHm equation: [m] : bhb + nad <==> acac + h + nadh
product: 060469
name: (R)-3-Hydroxybutanoate:NAD+ oxidoreductase
is: ENSMMUG00000002021.2
fast: false

127885
stoichiometry: 1.0
species: 037729
type: SpeciesReference

116146
stoichiometry: 1.0
species: 045935
type: SpeciesReference

083759
stoichiometry: 1.0
species: 028668
type: SpeciesReference

027578
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2_C37H54NO37S2X
type: Species

047405
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019156
name: zymosterol intermediate 2_C27H42O
type: Species

135072
stoichiometry: 1.0
species: 023950
type: SpeciesReference

114239
stoichiometry: 1.0
species: 037148
type: SpeciesReference

042307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019180
name: Phosphate_HO4P
type: Species

056623
stoichiometry: 1.0
species: 046307
type: SpeciesReference

035824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019168
name: IDP_C10H11N4O11P2
type: Species

138002
stoichiometry: 1.0
species: 030394
type: SpeciesReference

040861
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Superoxide anion_O2
type: Species

129248
stoichiometry: 2.0
species: 040414
type: SpeciesReference

087547
stoichiometry: 1.0
species: 027846
type: SpeciesReference

139605
stoichiometry: 1.0
species: 033761
type: SpeciesReference

045669
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: L-Thyroxine_C15H11I4NO4
type: Species

115481
stoichiometry: 1.0
species: 038791
type: SpeciesReference

050408
stoichiometry: 1.0
species: 042403
type: SpeciesReference

034153
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: carbonic acid_H2CO3
type: Species

068476
stoichiometry: 18.0
species: 034290
type: SpeciesReference

132461
stoichiometry: 2.0
species: 046500
type: SpeciesReference

072089
stoichiometry: 1.0
species: 042283
type: SpeciesReference

141426
stoichiometry: 1.0
species: 033591
type: SpeciesReference

021436
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: _4-Trimethylammoniobutanal_C7H16NO
type: Species

041453
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019144
name: Phenylacetic acid_C8H7O2
type: Species

020045
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 019205
type: Species

066522
stoichiometry: 2.0
species: 025565
type: SpeciesReference

137278
stoichiometry: 1.0
species: 042283
type: SpeciesReference