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209838
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kind: METRE
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209901
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name: pg_per_cells
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679053
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units: 209962
value: 0.2
name: d1
type: Parameter

679044
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units: dimensionless
value: 0.8
name: alpha
type: Parameter

209705
unit: 209730
unit: 209717
name: cells_per_mm3_day
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209962
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name: first_order_rate_constant
type: SBMLUnitsDef

MODEL1006230002
type: SBMLModel
parameter: 679035
parameter: 679045
units def: 209986
units def: 209875
units def: 209925
modified:
  W3 CDTF: Fri Jun 25 13:01:19 BST 2010
units def: 209705
parameter: 679044
units def: 209901
created:
  W3 CDTF: Fri Jun 25 13:01:19 BST 2010
units def: 209742
parameter: 679054
parameter: 679036
parameter: 679046
rule: 679027
length unit: 335510
parameter: 679031
parameter: 679041
rule: 679028
parameter: 679033
modified:
  W3 CDTF: Fri Jun 25 13:01:19 BST 2010
volume units: 950046
parameter: 679050
time units: 210023
curated: false
name: Waugh2006_WoundHealingMacrophageDynamics_Diabetic_ModelB
creator:
  ORG:
    orgname: University of Auckland
  n:
    given: Catherine
    family: Lloyd
units def: 209680
rule: 679026
parameter: 679032
units def: 209962
units def: 210023
units def: 209778
substance units: 178797
parameter: 679034
area units: area
units def: 209655
modified:
  W3 CDTF: Fri Jun 25 13:01:19 BST 2010
parameter: 679039
parameter: 679049
creator:
  ORG:
    orgname: University of Auckland
  n:
    given: Catherine
    family: Lloyd
parameter: 679040
rule: 679029
units def: 209826
notes: This a model from the article: Macrophage dynamics in diabetic wound dealing. Waugh HV, Sherratt JA. Bull Math Biol 2006 Jan;68(1):197-207 16794927 , Abstract: Wound healing in diabetes is a complex process, characterised by a chronic inflammation phase. The exact mechanism by which this occurs is not fully understood, and whilst several treatments for healing diabetic wounds exist, very little research has been conducted towards the causes of the extended inflammation phase. We describe a mathematical model which offers a possible explanation for diabetic wound healing in terms of the distribution of macrophage phenotypes being altered in the diabetic patient compared to normal wound repair. As a consequence of this, we put forward a suggestion for treatment based on rectifying the macrophage phenotype imbalance. This model was taken from the CellML repository and automatically converted to SBML. The original model was: Waugh HV, Sherratt JA. (2006) - version=1.0 The original CellML model was created by: Catherine Lloyd c.lloyd@auckland.ac.nz The University of Auckland This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitati…
parameter: 679053
is described by: http://identifiers.org/pubmed/16794927
compartment: 679021
creator:
  ORG:
    orgname: University of Auckland
  n:
    given: Catherine
    family: Lloyd

679040
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209888
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209986
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679033
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units: 209680
value: 200.0
name: phi_R
type: Parameter

679050
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value: 0.07
name: k4
type: Parameter

209742
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unit: 209754
name: cells_per_pg_day
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209937
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kind: GRAM
type: SBMLUnit

209875
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type: SBMLUnitsDef

679054
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units: 209962
value: 9.1
name: d2
type: Parameter

209862
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209667
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209814
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209913
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210011
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679034
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value: 6.0
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209974
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210023
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209998
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679045
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value: 0.05
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209717
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679039
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value: 21.94
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679049
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value: 0.002
name: k3
type: Parameter

679032
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679035
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value: NaN
name: K_T
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679021
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units: litre
size: 1.0
spatial dimensions: 3.0
type: Compartment

209949
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209692
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209754
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209925
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209802
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679046
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value: 0.693
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type: Parameter

679041
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units: 209705
value: 1.75
name: tau4
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679036
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units: 209826
value: -2.47
name: tau1
type: Parameter

209850
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679031
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value: NaN
name: time
type: Parameter

209778
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type: SBMLUnitsDef

209655
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