030451
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

974938
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

984119
stoichiometry: 1.0
species: metaid M 698
type: SpeciesReference

998726
units: 958314
value: 0.0
type: LocalParameter

078152
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

111433
stoichiometry: 1.0
species: metaid M 687
type: SpeciesReference

metaid E 439
boundary condition: false
is: S000001769
initial concentration: NaN
has only substance units: false
is: P33550
is: SBO:0000014
type: Species
in compartment: metaid C 2
notes: SHORT NAME: KTR2
constant: false
initial amount: NaN
name: YKR061W

025688
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 201
is: S000000863
has only substance units: false
boundary condition: false
name: YER061C
initial amount: NaN
initial concentration: NaN
notes: SHORT NAME: CEM1
in compartment: metaid C 2
is: P39525
is: SBO:0000014
constant: false
is: sce00061
type: Species

978179
stoichiometry: 1.0
species: metaid M 213
type: SpeciesReference

118656
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

027997
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

082600
stoichiometry: 1.0
species: metaid M 613
type: SpeciesReference

126603
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

080004
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R PEPTxtI
kinetic law: 129011
product: 128999
reactant: 128987
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of peptide
type: Reaction

metaid R POX1 10
name: Acyl-coenzyme A oxidase
reactant: 062096
is: SBO:0000176
modifier: 062144
product: 062120
type: Reaction
kinetic law: 062156
notes: SUBSYSTEM: Fatty acid degradation
product: 062132
is: http://identifiers.org/ec-code/1.3.3.6
reversible: false
reactant: 062108
fast: false

123514
stoichiometry: 1.0
species: metaid M 327
type: SpeciesReference

078743
stoichiometry: 1.0
species: metaid M 156
type: SpeciesReference

994848
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

058287
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R MSR1
product: 046821
is: http://identifiers.org/ec-code/6.1.1.19
fast: false
product: 046845
is: SBO:0000176
notes: SUBSYSTEM: tRNA synthesis
reversible: false
type: Reaction
name: Arginyl-tRNA synthetase, mitochondrial
reactant: 046809
modifier: 046857
kinetic law: 046869
reactant: 046797
reactant: 046785
product: 046833

metaid R UAcyl 5 1
kinetic law: 105489
product: 105477
reactant: 105465
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Acyl-[acyl-carrier-protein] transporter, mitochondrial
type: Reaction

123983
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

058892
stoichiometry: 1.0
species: metaid M 698
type: SpeciesReference

134622
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 202
initial amount: NaN
is: P40106
notes: SHORT NAME: HOR2
name: YER062C
boundary condition: false
in compartment: metaid C 2
is: sce00561
is: SBO:0000014
constant: false
type: Species
initial concentration: NaN
is: S000000864
has only substance units: false

124694
stoichiometry: 1.0
species: metaid M 425
type: SpeciesReference

085140
stoichiometry: 1.0
species: metaid M 77
type: SpeciesReference

095336
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

959505
stoichiometry: 1.0
species: metaid M 578
type: SpeciesReference

035517
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

072237
stoichiometry: 1.0
species: metaid M 687
type: SpeciesReference

001951
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

139959
units: 958314
value: 0.0
type: LocalParameter

076571
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

132973
stoichiometry: 1.0
species: metaid M 999
type: SpeciesReference

979129
stoichiometry: 1.0
species: metaid M 142
type: SpeciesReference

metaid R POX1 11
kinetic law: 062277
modifier: 062265
notes: SUBSYSTEM: Fatty acid degradation
is: SBO:0000176
reversible: false
fast: false
product: 062241
reactant: 062229
type: Reaction
reactant: 062217
product: 062253
is: http://identifiers.org/ec-code/1.3.3.6
name: Acyl-coenzyme A oxidase

064240
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

082829
stoichiometry: 1.0
species: metaid M 694
type: SpeciesReference

091375
stoichiometry: 1.0
species: metaid M 531
type: SpeciesReference

973614
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

135727
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 437
notes: SHORT NAME: GAP1
has only substance units: false
is: P19145
in compartment: metaid C 2
type: Species
is: SBO:0000014
name: YKR039W
is: S000001747
constant: false
initial amount: NaN
boundary condition: false
initial concentration: NaN

115102
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

118114
stoichiometry: 1.0
species: metaid M 716
type: SpeciesReference

133418
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 71
is: S000000498
notes: SHORT NAME: SUL1
type: Species
in compartment: metaid C 2
is: SBO:0000014
has only substance units: false
boundary condition: false
name: YBR294W
is: P38359
constant: false
initial concentration: NaN
initial amount: NaN

143213
stoichiometry: 0.023371
species: metaid M 241
type: SpeciesReference

034032
units: 958314
value: 9.2235E-4
type: LocalParameter

012427
stoichiometry: 1.0
species: metaid M 604
type: SpeciesReference

101560
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R GPM1 2
product: 017570
name: Phosphoglycerate mutase 1
reversible: true
kinetic law: 017594
reactant: 017558
fast: false
modifier: 017582
notes: SUBSYSTEM: Glycolysis / Gluconeogenesis
type: Reaction
is: SBO:0000176
is: http://identifiers.org/ec-code/5.4.2.1

metaid R EPISTxtO
kinetic law: 135606
product: 135594
reactant: 135582
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of episterol
type: Reaction

977085
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R NAM2
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reactant: 048108
kinetic law: 048181
reactant: 048096
reversible: false
reactant: 048120
product: 048157
product: 048145
fast: false
product: 048133
modifier: 048169
is: SBO:0000176
type: Reaction
notes: SUBSYSTEM: tRNA synthesis
name: Leucyl-tRNA synthetase, mitochondrial

994620
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

138681
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R PTRSCxtI
kinetic law: 129515
product: 129503
reactant: 129491
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of putrescine
type: Reaction

065517
units: 958314
value: 0.0
type: LocalParameter

metaid E 438
initial amount: NaN
notes: SHORT NAME: YSR3
is: S000001761
has only substance units: false
type: Species
is: P23501
name: YKR053C
is: SBO:0000014
in compartment: metaid C 2
boundary condition: false
initial concentration: NaN
constant: false
is: sce00600

metaid E 200
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is: Q12119
name: YER060W-A
initial amount: NaN
type: Species
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is: SBO:0000014
constant: false
is: S000002958
notes: SHORT NAME: FCY22
initial concentration: NaN
boundary condition: false

101415
stoichiometry: 1.0
species: metaid M 576
type: SpeciesReference

079318
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

075487
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

139731
stoichiometry: 1.0
species: metaid M 1079
type: SpeciesReference

108857
stoichiometry: 1.0
species: metaid M 733
type: SpeciesReference

076270
stoichiometry: 1.0
species: metaid M 852
type: SpeciesReference

020642
stoichiometry: 4.0
species: metaid M 776
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metaid R GPM1 1
reversible: true
kinetic law: 017498
product: 017474
type: Reaction
is: http://identifiers.org/ec-code/5.4.2.1
name: Phosphoglycerate mutase 1
modifier: 017486
is: SBO:0000176
notes: SUBSYSTEM: Glycolysis / Gluconeogenesis
fast: false
reactant: 017462

metaid R U113
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product: 085681
reactant: 085669
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Transport of methane, mitochondrial
type: Reaction

082360
stoichiometry: 1.0
species: metaid M 311
type: SpeciesReference

964514
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 70
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initial amount: NaN
notes: SHORT NAME: CTP1
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is: S000000495
type: Species
initial concentration: NaN
is: P38152
name: YBR291C
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is: SBO:0000014
has only substance units: false

083624
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

088706
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species: metaid M 831
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metaid E 205
type: Species
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is: SBO:0000014
constant: false
notes: SHORT NAME: RNR1
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is: sce00230
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initial concentration: NaN
has only substance units: false
is: sce00480
initial amount: NaN
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081525
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

999329
stoichiometry: 1.0
species: metaid M 218
type: SpeciesReference

079101
units: 958314
value: 0.0
type: LocalParameter

006304
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

144034
stoichiometry: 0.039
species: metaid M 316
type: SpeciesReference

026312
stoichiometry: 1.0
species: metaid M 465
type: SpeciesReference

049822
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

128393
stoichiometry: 1.0
species: metaid M 1076
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073827
units: 958314
value: 0.0
type: LocalParameter

019595
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

133118
units: 958314
value: 0.0
type: LocalParameter

963967
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid E 206
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initial concentration: NaN
is: P40047
is: sce00310
is: sce00010
name: YER073W
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is: sce00340
is: sce00410
is: sce00071
is: sce00620
notes: SHORT NAME: ALD5
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has only substance units: false
is: S000000875
initial amount: NaN
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is: sce00650
is: sce00561
is: sce00280
type: Species
is: SBO:0000014
constant: false
is: sce00640

054468
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R EPISTxtI
kinetic law: 124538
product: 124526
reactant: 124514
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of episterol
type: Reaction

984853
stoichiometry: 1.0
species: metaid M 967
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013469
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species: metaid M 177
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061385
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species: metaid M 321
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is: sce00630
boundary condition: false
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notes: SHORT NAME: ICL1
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type: Species
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is: SBO:0000014
initial concentration: NaN
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095817
stoichiometry: 1.0
species: metaid M 751
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073935
units: 958314
value: 0.0
type: LocalParameter

032782
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

025363
stoichiometry: 1.0
species: metaid M 267
type: SpeciesReference

117366
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R U71
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kinetic law: 101838
reversible: false
reactant: 101789
product: 101826
name: Hypothetical enzyme
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type: Reaction
notes: SUBSYSTEM: Thiamine (vitamin B1) metabolism
product: 101814
is: SBO:0000176
product: 101802

994500
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

047195
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species: metaid M 263
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036228
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

127432
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

033093
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

083310
stoichiometry: 1.0
species: metaid M 693
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metaid M 518
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initial concentration: NaN
initial amount: NaN
type: Species
is: CHEBI:30904
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boundary condition: false
constant: false
name: homoisocitrate
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metaid R GNxtI
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product: 126303
reactant: 126291
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of guanine
type: Reaction

metaid R POX1 12
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product: 062373
product: 062361
reactant: 062349
name: Acyl-coenzyme A oxidase
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is: SBO:0000176
kinetic law: 062397
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type: Reaction
reversible: false
notes: SUBSYSTEM: Fatty acid degradation
fast: false

095961
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

129191
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R ASP32
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modifier: 971493
notes: SUBSYSTEM: Arginine metabolism
type: Reaction
is: http://identifiers.org/ec-code/3.5.1.1
kinetic law: 971505
product: 971481
reactant: 971457
reversible: false
name: L-asparaginase 2
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product: 971469

128237
stoichiometry: 1.0
species: metaid M 695
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063469
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

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is: SBO:0000014
constant: false
boundary condition: false
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initial amount: NaN
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105285
units: 958314
value: 0.08812361359969
type: LocalParameter

097530
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

082901
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

053782
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species: metaid M 88
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004567
units: 958314
value: 0.0
type: LocalParameter

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boundary condition: false
in compartment: metaid C 2
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initial amount: NaN
notes: SHORT NAME: PHO11
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metaid M 519
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name: H2S
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type: Species
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constant: false
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initial concentration: NaN

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species: metaid M 149
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

003590
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

100731
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value: 0.0
type: LocalParameter

071187
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species: metaid M 479
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metaid R ASP31
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notes: SUBSYSTEM: Asparagine metabolism
is: SBO:0000176
modifier: 971384
product: 971360
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name: L-asparaginase 2
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fast: false
reactant: 971348
product: 971372

068304
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

982625
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

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type: Species
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is: P00815
is: SBO:0000014
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name: YCL030C
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049931
units: 958314
value: 1000.0
name: UPPER_BOUND
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metaid R ARO7
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product: 970477
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type: Reaction
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modifier: 970489
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initial concentration: NaN
initial amount: NaN
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type: Species
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species: metaid M 31
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species: metaid M 218
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boundary condition: false
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constant: false
name: YKL211C
notes: SHORT NAME: TRP3

111154
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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011982
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species: metaid M 262
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value: 0.0
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value: 0.0
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metaid R PTRSCxtO
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product: 140585
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notes: SUBSYSTEM: Exchange reactions
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reversible: false
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initial concentration: NaN
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129083
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species: metaid M 756
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142491
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid R ARO8
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notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
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118006
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051580
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value: 0.00376433561012
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metaid R PEPTxtO
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species: metaid M 203
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984961
stoichiometry: 1.0
species: metaid M 694
type: SpeciesReference

140392
units: 958314
value: 0.0
type: LocalParameter

metaid M 514
constant: false
in compartment: metaid C 3
is: CHEBI:15971
boundary condition: false
name: L-histidine
is: SBO:0000299
has only substance units: false
initial concentration: NaN
type: Species
initial amount: NaN

metaid R CYSxtI
kinetic law: 123526
product: 123514
reactant: 123502
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of L-cysteine
type: Reaction

093601
stoichiometry: 1.0
species: metaid M 368
type: SpeciesReference

053890
stoichiometry: 1.0
species: metaid M 792
type: SpeciesReference

114404
stoichiometry: 1.0
species: metaid M 438
type: SpeciesReference

963811
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

metaid E 207
initial concentration: NaN
initial amount: NaN
type: Species
in compartment: metaid C 2
is: S000000883
is: P40054
notes: SHORT NAME: SER3
constant: false
name: YER081W
is: sce00260
boundary condition: false
is: SBO:0000014
has only substance units: false

962028
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

040258
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

962319
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R KGD1
is: http://identifiers.org/ec-code/1.2.4.2
product: 036768
product: 036744
type: Reaction
reversible: false
is: SBO:0000176
modifier: 036780
reactant: 036732
name: Alpha-ketoglutarate dehydrogenase
reactant: 036720
kinetic law: 036792
product: 036756
notes: SUBSYSTEM: Citrate cycle (TCA cycle)
fast: false
reactant: 036708

100622
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

986683
units: 958314
value: 0.0
type: LocalParameter

metaid E 78
is: SBO:0000014
type: Species
initial concentration: NaN
is: sce00010
is: P17709
is: sce00052
name: YCL040W
in compartment: metaid C 2
is: S000000545
has only substance units: false
boundary condition: false
notes: SHORT NAME: GLK1
is: sce00500
initial amount: NaN
constant: false

073610
stoichiometry: 1.0
species: metaid M 358
type: SpeciesReference

068413
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

043721
stoichiometry: 1.0
species: metaid M 692
type: SpeciesReference

060928
stoichiometry: 1.0
species: metaid M 692
type: SpeciesReference

083202
stoichiometry: 1.0
species: metaid M 891
type: SpeciesReference

968979
stoichiometry: 1.0
species: metaid M 733
type: SpeciesReference

metaid M 515
initial amount: NaN
boundary condition: false
constant: false
in compartment: metaid C 1
name: hydroxide
is: CHEBI:16234
initial concentration: NaN
is: SBO:0000299
has only substance units: false
type: Species

973409
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

128694
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

136211
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 208
name: YER086W
boundary condition: false
notes: SHORT NAME: ILV1
is: P00927
constant: false
is: sce00260
initial concentration: NaN
is: sce00290
is: SBO:0000014
has only substance units: false
is: S000000888
initial amount: NaN
type: Species
in compartment: metaid C 2

141079
stoichiometry: 1.0
species: metaid M 840
type: SpeciesReference

metaid E 430
in compartment: metaid C 2
constant: false
initial concentration: NaN
is: SBO:0000014
initial amount: NaN
name: YKL203C
notes: SHORT NAME: TOR2
is: S000001686
boundary condition: false
has only substance units: false
is: P32600
type: Species

054252
stoichiometry: 1.0
species: metaid M 698
type: SpeciesReference

049063
units: 958314
value: 0.0
type: LocalParameter

973554
stoichiometry: 1.0
species: metaid M 756
type: SpeciesReference

048578
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R ARO3
name: Phospho-2-keto-3-deoxyheptonate aldolase
product: 970261
reactant: 970237
notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
is: SBO:0000176
modifier: 970273
reversible: false
product: 970249
is: http://identifiers.org/ec-code/2.5.1.54
type: Reaction
kinetic law: 970285
reactant: 970225
fast: false

090510
stoichiometry: 1.0
species: metaid M 241
type: SpeciesReference

139500
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

094445
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

020534
units: 958314
value: 0.0
type: LocalParameter

metaid E 73
is: SBO:0000014
initial amount: NaN
boundary condition: false
in compartment: metaid C 2
initial concentration: NaN
is: sce00500
has only substance units: false
is: sce00052
name: YBR299W
is: S000000503
constant: false
notes: SHORT NAME: MAL32
is: P38158
type: Species

035409
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

072345
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

126712
stoichiometry: 1.0
species: metaid M 1056
type: SpeciesReference

metaid R OPI3 2
type: Reaction
product: 051860
name: Methylene-fatty-acyl-phospholipid synthase
modifier: 051873
is: http://identifiers.org/ec-code/2.1.1.16
reactant: 051834
kinetic law: 051886
product: 051847
notes: SUBSYSTEM: Phospholipid biosynthesis
fast: false
reversible: false
reactant: 051822
is: SBO:0000176

140946
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 508
constant: false
is: S000004506
in compartment: metaid C 2
name: YML042W
type: Species
boundary condition: false
initial concentration: NaN
is: SBO:0000014
has only substance units: false
notes: SHORT NAME: CAT2
initial amount: NaN
is: sce00252
is: P32796

102936
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

metaid R PCT1
notes: SUBSYSTEM: Phospholipid biosynthesis
name: Choline-phosphate cytidylyltransferase
modifier: 052782
kinetic law: 052794
is: SBO:0000176
reactant: 052734
reversible: false
product: 052758
reactant: 052746
fast: false
type: Reaction
is: http://identifiers.org/ec-code/2.7.7.15
product: 052770

004265
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

127684
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid R MEP2
name: Ammonium transporter MEP2
modifier: 043009
product: 042997
fast: false
reactant: 042985
type: Reaction
reversible: true
is: SBO:0000185
kinetic law: 043021
notes: SUBSYSTEM: Transport, extracellular

metaid M 512
has only substance units: false
initial concentration: NaN
in compartment: metaid C 1
is: SBO:0000299
notes: FORMULA: C6H11OSR
is: C05749
boundary condition: false
type: Species
name: hexanoyl-[acp]
constant: false
initial amount: NaN

metaid E 435
is: SBO:0000014
is: sce00650
name: YKR009C
notes: SHORT NAME: FOX2
is: sce00350
has only substance units: false
boundary condition: false
is: sce00051
is: Q02207
is: sce00260
initial concentration: NaN
initial amount: NaN
is: sce00460
is: S000001717
type: Species
in compartment: metaid C 2
constant: false

122309
units: 958314
value: 0.0
type: LocalParameter

metaid M 513
name: hexanoyl-CoA
initial amount: NaN
type: Species
initial concentration: NaN
constant: false
is: CHEBI:27540
is: SBO:0000299
has only substance units: false
boundary condition: false
in compartment: metaid C 2

metaid R ARO4
kinetic law: 970405
notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
is: http://identifiers.org/ec-code/2.5.1.54
reversible: false
name: Phospho-2-keto-3-deoxyheptonate aldolase
reactant: 970345
is: SBO:0000176
modifier: 970393
fast: false
product: 970369
reactant: 970357
type: Reaction
product: 970381

078260
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 72
name: YBR298C
type: Species
is: SBO:0000014
initial amount: NaN
notes: SHORT NAME: MAL31
in compartment: metaid C 2
has only substance units: false
is: P38156
is: S000000502
boundary condition: false
initial concentration: NaN
constant: false

133526
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 436
boundary condition: false
in compartment: metaid C 2
has only substance units: false
type: Species
is: sce00564
is: S000001739
constant: false
initial concentration: NaN
name: YKR031C
notes: SHORT NAME: SPO14
initial amount: NaN
is: SBO:0000014
is: P36126

metaid R LACxtO
kinetic law: 138224
product: 138212
reactant: 138200
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of (R)-lactate
type: Reaction

metaid E 509
name: YML054C
notes: SHORT NAME: CYB2
is: P00175
is: SBO:0000014
is: sce00620
has only substance units: false
initial amount: NaN
boundary condition: false
is: S000004518
initial concentration: NaN
constant: false
in compartment: metaid C 2
type: Species

978023
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

025796
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

968537
units: 958314
value: 0.0
type: LocalParameter

994957
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid R MEP1
is: SBO:0000185
product: 042901
reversible: true
reactant: 042889
kinetic law: 042925
type: Reaction
modifier: 042913
notes: SUBSYSTEM: Transport, extracellular
name: Ammonium transporter MEP1
fast: false

058396
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

078369
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

034140
units: 958314
value: 0.0
type: LocalParameter

metaid R U102
name: NAD+ nucleosidase
product: 084646
is: SBO:0000176
reversible: false
fast: false
product: 084659
notes: SUBSYSTEM: NAD biosynthesis
kinetic law: 084671
is: http://identifiers.org/ec-code/3.2.2.5
reactant: 084634
type: Reaction

964624
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

074512
stoichiometry: 1.0
species: metaid M 892
type: SpeciesReference

027563
stoichiometry: 1.0
species: metaid M 468
type: SpeciesReference

126928
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

062084
units: 958314
value: 0.0
type: LocalParameter

105840
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid E 75
is: P04173
boundary condition: false
in compartment: metaid C 2
initial concentration: NaN
is: sce00290
has only substance units: false
constant: false
is: S000000523
name: YCL018W
type: Species
is: SBO:0000014
initial amount: NaN
notes: SHORT NAME: LEU2

064963
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

031839
units: 958314
value: 0.0
type: LocalParameter

037613
stoichiometry: 2.0
species: metaid M 463
type: SpeciesReference

076162
stoichiometry: 1.0
species: metaid M 650
type: SpeciesReference

065625
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

123875
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

115211
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 506
notes: SHORT NAME: APT1
in compartment: metaid C 2
boundary condition: false
constant: false
type: Species
initial concentration: NaN
is: S000004484
is: P49435
has only substance units: false
is: sce00230
name: YML022W
is: SBO:0000014
initial amount: NaN

079426
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid M 510
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initial concentration: NaN
initial amount: NaN
is: CHEBI:15525
name: palmitoyl-CoA
in compartment: metaid C 2
is: SBO:0000299
boundary condition: false
type: Species
has only substance units: false

metaid E 433
constant: false
is: P28272
is: SBO:0000014
is: sce00240
has only substance units: false
name: YKL216W
boundary condition: false
initial concentration: NaN
is: S000001699
in compartment: metaid C 2
type: Species
initial amount: NaN
notes: SHORT NAME: URA1

118884
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

012535
stoichiometry: 1.0
species: metaid M 557
type: SpeciesReference

078899
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

977193
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

064131
units: 958314
value: 0.0
type: LocalParameter

metaid R ARO2
type: Reaction
notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
reversible: false
kinetic law: 970165
reactant: 970117
product: 970141
product: 970129
fast: false
name: Chorismate synthase
is: SBO:0000176
is: http://identifiers.org/ec-code/4.2.3.5
modifier: 970153

075330
stoichiometry: 1.0
species: metaid M 341
type: SpeciesReference

050775
stoichiometry: 1.0
species: metaid M 146
type: SpeciesReference

006739
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 74
notes: SHORT NAME: PGS1
is: SBO:0000014
type: Species
initial amount: NaN
is: S000000510
name: YCL004W
in compartment: metaid C 2
is: sce00564
is: P25578
has only substance units: false
constant: false
boundary condition: false
initial concentration: NaN
is: sce00260

000207
units: 958314
value: 0.0
type: LocalParameter

130092
stoichiometry: 1.0
species: metaid M 844
type: SpeciesReference

metaid E 507
constant: false
type: Species
is: sce00230
is: P15274
name: YML035C
has only substance units: false
boundary condition: false
is: SBO:0000014
initial amount: NaN
initial concentration: NaN
notes: SHORT NAME: AMD1
is: S000004498
in compartment: metaid C 2

metaid R OPI3 1
product: 051736
notes: SUBSYSTEM: Phospholipid biosynthesis
is: http://identifiers.org/ec-code/2.1.1.16
name: Methylene-fatty-acyl-phospholipid synthase
product: 051724
modifier: 051748
reactant: 051700
is: SBO:0000176
reversible: false
kinetic law: 051760
fast: false
reactant: 051712
type: Reaction

998618
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 434
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in compartment: metaid C 2
constant: false
is: P36035
notes: SHORT NAME: JEN1
is: SBO:0000014
boundary condition: false
is: S000001700
name: YKL217W
initial concentration: NaN
has only substance units: false
type: Species

metaid M 511
name: hexanoyl-[acp]
has only substance units: false
constant: false
initial amount: NaN
is: C05749
boundary condition: false
notes: FORMULA: C6H11OSR
is: SBO:0000299
in compartment: metaid C 2
type: Species
initial concentration: NaN

111952
stoichiometry: 1.0
species: metaid M 857
type: SpeciesReference

metaid R MEP3
modifier: 043107
name: Ammonium transporter MEP3
product: 043095
type: Reaction
reversible: true
notes: SUBSYSTEM: Transport, extracellular
reactant: 043083
fast: false
kinetic law: 043119
is: SBO:0000185

112813
stoichiometry: 1.0
species: metaid M 223
type: SpeciesReference

126195
units: 958314
value: 0.0
type: LocalParameter

metaid E 650
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has only substance units: false
is: sce00230
type: Species
is: sce00010
is: sce00710
is: sce00620
name: YOR347C
constant: false
boundary condition: false
notes: SHORT NAME: PYK2
is: S000005874
initial amount: NaN
is: P52489
in compartment: metaid C 2
initial concentration: NaN

051544
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

017210
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

091495
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

031405
stoichiometry: 1.0
species: metaid M 693
type: SpeciesReference

016425
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 505
name: YML008C
notes: SHORT NAME: ERG6
is: P25087
boundary condition: false
constant: false
is: SBO:0000014
initial amount: NaN
type: Species
in compartment: metaid C 2
initial concentration: NaN
has only substance units: false
is: S000004467
is: sce00100

000423
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

138356
units: 958314
value: 0.0
type: LocalParameter

027419
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

049712
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R NH3xtI
kinetic law: 128417
product: 128405
reactant: 128393
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of NH3
type: Reaction

143333
stoichiometry: 0.051
species: metaid M 490
type: SpeciesReference

111372
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

973987
stoichiometry: 1.0
species: metaid M 327
type: SpeciesReference

061879
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

metaid E 504
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is: S000004463
initial concentration: NaN
is: P50107
notes: SHORT NAME: GLO1
constant: false
is: SBO:0000014
initial amount: NaN
type: Species
in compartment: metaid C 2
has only substance units: false
name: YML004C
boundary condition: false

973337
stoichiometry: 1.0
species: metaid M 632
type: SpeciesReference

073719
units: 958314
value: 0.0
type: LocalParameter

969040
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

142274
stoichiometry: 1.0
species: metaid M 1109
type: SpeciesReference

026469
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

086778
stoichiometry: 1.0
species: metaid M 208
type: SpeciesReference

097842
units: 958314
value: 0.0
type: LocalParameter

000363
stoichiometry: 1.0
species: metaid M 718
type: SpeciesReference

990566
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

983866
units: 958314
value: 0.0
type: LocalParameter

metaid R C160xtI
kinetic law: 122683
product: 122671
reactant: 122659
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of palmitic acid
type: Reaction

metaid R RIB1
reactant: 068449
product: 068461
is: SBO:0000176
product: 068473
reversible: false
modifier: 068497
kinetic law: 068509
is: http://identifiers.org/ec-code/3.5.4.25
notes: SUBSYSTEM: Riboflavin metabolism
product: 068485
type: Reaction
name: GTP cyclohydrolase-2
fast: false

015048
stoichiometry: 1.0
species: metaid M 578
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metaid R CDA1
is: SBO:0000176
kinetic law: 977049
name: Chitin deacetylase 1
notes: SUBSYSTEM: Aminosugars metabolism
reactant: 977001
fast: false
product: 977013
reversible: false
modifier: 977037
type: Reaction
is: http://identifiers.org/ec-code/3.5.1.41
product: 977025

981814
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R U82
product: 103080
name: Pyridoxine kinase
reversible: false
reactant: 103044
reactant: 103056
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.35
fast: false
product: 103068
is: SBO:0000176
kinetic law: 103092
notes: SUBSYSTEM: Pyridoxine (vitamin B6) metabolism

020848
stoichiometry: 1.0
species: metaid M 215
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024018
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 503
notes: SHORT NAME: HMG2
boundary condition: false
in compartment: metaid C 2
has only substance units: false
type: Species
initial concentration: NaN
constant: false
is: S000004442
is: P12684
is: SBO:0000014
initial amount: NaN
is: sce00100
name: YLR450W

021293
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

042352
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R ENO1
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product: 990734
is: http://identifiers.org/ec-code/4.2.1.11
kinetic law: 990758
reversible: true
name: Enolase 1
fast: false
notes: SUBSYSTEM: Glycolysis / Gluconeogenesis
modifier: 990746
type: Reaction
is: SBO:0000176

087355
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid R U187
reactant: 092433
fast: false
type: Reaction
kinetic law: 092457
reactant: 092421
product: 092445
reversible: false
notes: SUBSYSTEM: Transport, extracellular
name: Transport of thymidine, extracellular
is: SBO:0000185

970321
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

020992
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

007415
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

093063
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

051436
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

072864
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species: metaid M 614
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metaid R CDA2
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product: 977121
product: 977133
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kinetic law: 977157
notes: SUBSYSTEM: Aminosugars metabolism
reactant: 977109
reversible: false
name: Chitin deacetylase 2
modifier: 977145
type: Reaction

007971
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species: metaid M 118
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965312
stoichiometry: 1.0
species: metaid M 501
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986466
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value: 0.0
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metaid R U172
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kinetic law: 090906
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product: 090894
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reactant: 090870
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notes: SUBSYSTEM: Transport, extracellular

metaid E 502
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043299
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047494
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species: metaid M 177
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144181
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species: metaid M 569
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metaid R ENO2
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product: 990830
reversible: true
is: http://identifiers.org/ec-code/4.2.1.11
modifier: 990843
notes: SUBSYSTEM: Glycolysis / Gluconeogenesis
fast: false
name: Enolase 2
reactant: 990818
kinetic law: 990855

086550
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128950
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959614
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species: metaid M 214
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998834
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121258
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043565
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species: metaid M 178
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968319
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species: metaid M 687
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060700
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metaid E 501
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metaid R U60
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notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
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type: Reaction
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is: http://identifiers.org/ec-code/3.7.1.2

metaid E 654
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metaid E 440
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constant: false
initial concentration: NaN

080378
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141465
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116069
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105623
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012977
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970549
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962174
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020317
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metaid E 68
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metaid E 69
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101862
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094228
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species: metaid M 978
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978685
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name: OBJECTIVE_COEFFICIENT
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109506
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value: 1000.0
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metaid E 500
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metaid E 653
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128538
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961095
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value: 0.03577801499999
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142177
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species: metaid M 968
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metaid R CYSxtO
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product: 134574
reactant: 134562
notes: SUBSYSTEM: Exchange reactions
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fast: false
reversible: false
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096455
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value: 0.0
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052806
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137392
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987188
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species: metaid M 461
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070946
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species: metaid M 746
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metaid R UAcyl 2 1
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product: 105225
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notes: SUBSYSTEM: Transport, mitochondrial
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fast: false
reversible: true
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090966
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species: metaid M 501
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085032
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079209
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140729
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value: 6.81235932928619
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046761
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044661
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metaid R RIB5
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product: 068593
modifier: 068618
kinetic law: 068630
product: 068605
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notes: SUBSYSTEM: Riboflavin metabolism

057770
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species: metaid M 262
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metaid E 652
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notes: SHORT NAME: PDE2
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003445
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087828
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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959931
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979345
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species: metaid M 613
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094373
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086874
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species: metaid M 865
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000784
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967047
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992092
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140220
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129611
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metaid R TRExtO
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product: 141936
reactant: 141924
notes: SUBSYSTEM: Exchange reactions
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fast: false
reversible: false
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000123
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species: metaid M 691
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058179
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value: 0.0
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139176
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value: 1000.0
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name: OBJECTIVE_COEFFICIENT
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968102
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species: metaid M 795
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118957
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species: metaid M 230
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name: OBJECTIVE_COEFFICIENT
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133959
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061277
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species: metaid M 214
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035625
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969959
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value: 1000.0
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086261
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species: metaid M 610
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072455
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value: 1000.0
name: UPPER_BOUND
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118439
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metaid R ASP33
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985913
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value: 1000.0
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080221
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species: metaid M 795
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028774
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value: 0.0
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027839
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127792
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value: 0.0
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metaid R PSA1
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type: Reaction
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modifier: 064915
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036372
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965420
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034369
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species: metaid M 39
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value: 1000.0
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modifier: 971709
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reactant: 971673
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062361
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metaid R GNxtO
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product: 137368
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notes: SUBSYSTEM: Exchange reactions
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reversible: false
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080161
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987297
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species: metaid M 851
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species: metaid M 569
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110719
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species: metaid M 795
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metaid R FAS2 2 1
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087936
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metaid R FAS2 2 2
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kinetic law: 001012
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product: 000976
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057613
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089656
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142599
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122901
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123996
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115114
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139031
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110611
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094661
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973771
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product: 052205
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098769
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020630
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078164
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082613
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species: metaid M 348
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030463
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981706
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085152
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994512
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initial concentration: NaN
is: CHEBI:16240
is: SBO:0000299
in compartment: metaid C 2
has only substance units: false
boundary condition: false
initial amount: NaN
type: Species
constant: false
name: hydrogen peroxide

100634
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

073622
stoichiometry: 1.0
species: metaid M 687
type: SpeciesReference

060916
stoichiometry: 1.0
species: metaid M 231
type: SpeciesReference

068425
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

986695
stoichiometry: 1.0
species: metaid M 13
type: SpeciesReference

054240
units: 958314
value: 0.0
type: LocalParameter

049051
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

110287
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

973542
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

964902
stoichiometry: 1.0
species: metaid M 578
type: SpeciesReference

metaid R FOX2 6
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reactant: 008443
product: 008455
is: SBO:0000176
is: http://identifiers.org/ec-code/1.1.1.-
modifier: 008479
reversible: false
type: Reaction
reactant: 008431
kinetic law: 008491
product: 008467
notes: SUBSYSTEM: Fatty acid degradation
name: D-3-hydroxyacyl-CoA dehydrogenase

128682
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

136223
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 504
boundary condition: false
is: SBO:0000299
name: heme
initial amount: NaN
has only substance units: false
constant: false
initial concentration: NaN
is: CHEBI:30413
type: Species
in compartment: metaid C 1

006449
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

000868
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

082262
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

982613
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid E 89
initial concentration: NaN
name: YCR036W
is: P25332
initial amount: NaN
constant: false
type: Species
is: SBO:0000014
is: S000000632
is: sce00030
notes: SHORT NAME: RBK1
boundary condition: false
has only substance units: false
in compartment: metaid C 2

049943
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R AONAxtI
kinetic law: 121583
product: 121571
reactant: 121559
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of 8-amino-7-oxononanoate
type: Reaction

054300
stoichiometry: 1.0
species: metaid M 791
type: SpeciesReference

111215
stoichiometry: 1.0
species: metaid M 363
type: SpeciesReference

111142
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

992273
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species: metaid M 691
type: SpeciesReference

011994
stoichiometry: 1.0
species: metaid M 613
type: SpeciesReference

975300
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 505
is: SBO:0000299
initial concentration: NaN
name: palmitic acid
in compartment: metaid C 2
is: CHEBI:15756
initial amount: NaN
boundary condition: false
has only substance units: false
constant: false
type: Species

051592
stoichiometry: 1.0
species: metaid M 723
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metaid E 88
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initial concentration: NaN
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has only substance units: false
in compartment: metaid C 2
notes: SHORT NAME: FEN1
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118018
stoichiometry: 1.0
species: metaid M 688
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007827
stoichiometry: 1.0
species: metaid M 102
type: SpeciesReference

983058
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

019692
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

083746
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

989939
stoichiometry: 1.0
species: metaid M 644
type: SpeciesReference

metaid R FOX2 8
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product: 008695
is: http://identifiers.org/ec-code/1.1.1.-
type: Reaction
reactant: 008683
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reactant: 008671
modifier: 008720
notes: SUBSYSTEM: Fatty acid degradation
name: D-3-hydroxyacyl-CoA dehydrogenase
kinetic law: 008732
product: 008708
reversible: false

994404
stoichiometry: 1.0
species: metaid M 694
type: SpeciesReference

metaid E 420
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has only substance units: false
in compartment: metaid C 2
is: sce00052
constant: false
is: sce00030
is: P33401
type: Species
name: YKL127W
notes: SHORT NAME: PGM1
initial amount: NaN
is: sce00500
initial concentration: NaN
is: SBO:0000014
boundary condition: false
is: S000001610

048361
stoichiometry: 1.0
species: metaid M 214
type: SpeciesReference

025243
stoichiometry: 1.0
species: metaid M 351
type: SpeciesReference

064975
units: 958314
value: 0.32034873
type: LocalParameter

metaid E 87
is: P25356
notes: SHORT NAME: BPH1
name: YCR032W
initial amount: NaN
boundary condition: false
constant: false
type: Species
is: SBO:0000014
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initial concentration: NaN
is: S000000628
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085260
stoichiometry: 1.0
species: metaid M 74
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037601
stoichiometry: 1.0
species: metaid M 271
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074500
units: 958314
value: 0.0
type: LocalParameter

062072
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

126916
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

968760
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R FOX2 3
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type: Reaction
reactant: 008080
modifier: 008116
product: 008092
name: D-3-hydroxyacyl-CoA dehydrogenase
product: 008104
is: http://identifiers.org/ec-code/1.1.1.-
kinetic law: 008128
notes: SUBSYSTEM: Fatty acid degradation
fast: false
reactant: 008068
is: SBO:0000176

metaid E 421
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has only substance units: false
is: SBO:0000014
boundary condition: false
is: sce00790
is: S000001615
notes: SHORT NAME: RMA1
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in compartment: metaid C 2
initial concentration: NaN
initial amount: NaN
type: Species
constant: false

123887
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

027551
units: 958314
value: 0.0
type: LocalParameter

012523
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

989491
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

977181
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

106790
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

076150
stoichiometry: 1.0
species: metaid M 535
type: SpeciesReference

metaid R ALAVxtI
kinetic law: 121330
product: 121318
reactant: 121306
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of 5-aminolevulinate
type: Reaction

115223
units: 958314
value: 0.0
type: LocalParameter

065613
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

098613
stoichiometry: 3.0
species: metaid M 733
type: SpeciesReference

metaid R SRT1
reactant: 075099
notes: SUBSYSTEM: Quinone biosynthesis
product: 075123
is: SBO:0000176
reactant: 075111
modifier: 075147
product: 075135
reversible: false
name: Cis-prenyltransferase
kinetic law: 075159
type: Reaction
is: http://identifiers.org/ec-code/2.5.1.-
fast: false

metaid E 86
is: P25621
type: Species
is: SBO:0000014
name: YCR028C
initial amount: NaN
in compartment: metaid C 2
notes: SHORT NAME: FEN2
has only substance units: false
initial concentration: NaN
is: S000000623
constant: false
boundary condition: false

118728
stoichiometry: 1.0
species: metaid M 392
type: SpeciesReference

964611
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

050763
units: 958314
value: 0.08807001836371
type: LocalParameter

metaid E 422
has only substance units: false
initial concentration: NaN
is: SBO:0000014
name: YKL140W
is: sce00960
notes: SHORT NAME: TGL1
in compartment: metaid C 2
initial amount: NaN
type: Species
constant: false
boundary condition: false
is: S000001623
is: P34163

metaid R FOX2 2
kinetic law: 008007
reactant: 007959
product: 007971
product: 007983
name: D-3-hydroxyacyl-CoA dehydrogenase
is: SBO:0000176
reactant: 007947
is: http://identifiers.org/ec-code/1.1.1.-
type: Reaction
notes: SUBSYSTEM: Fatty acid degradation
fast: false
reversible: false
modifier: 007995

metaid R U101
reactant: 084538
is: http://identifiers.org/ec-code/3.1.2.-
product: 084562
fast: false
product: 084550
notes: SUBSYSTEM: NAD biosynthesis
kinetic law: 084574
name: NADP phosphatase
type: Reaction
is: SBO:0000176
reversible: false

992189
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

123310
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

989347
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

020522
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

094433
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

126700
units: 958314
value: 0.0
type: LocalParameter

027852
stoichiometry: 1.0
species: metaid M 468
type: SpeciesReference

metaid E 85
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type: Species
is: SBO:0000014
name: YCR024C-A
is: S000000619
initial amount: NaN
initial concentration: NaN
notes: SHORT NAME: PMP1
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in compartment: metaid C 2
is: P32903
has only substance units: false

072357
stoichiometry: 1.0
species: metaid M 613
type: SpeciesReference

129779
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

115780
stoichiometry: 1.0
species: metaid M 337
type: SpeciesReference

139512
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

127672
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R TRExtI
kinetic law: 130866
product: 130854
reactant: 130841
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of alpha,alpha-trehalose
type: Reaction

136944
stoichiometry: 1.0
species: metaid M 1046
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metaid E 423
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is: S000001624
is: SBO:0000014
is: P33421
has only substance units: false
boundary condition: false
name: YKL141W
initial amount: NaN
in compartment: metaid C 2
is: sce00020
is: sce00190
initial concentration: NaN
constant: false
type: Species

metaid M 500
in compartment: metaid C 1
initial concentration: NaN
is: SBO:0000299
is: CHEBI:16750
boundary condition: false
name: guanosine
type: Species
constant: false
initial amount: NaN
has only substance units: false

metaid R FOX2 5
reactant: 008322
kinetic law: 008371
product: 008347
product: 008334
fast: false
modifier: 008359
is: http://identifiers.org/ec-code/1.1.1.-
reversible: false
name: D-3-hydroxyacyl-CoA dehydrogenase
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reactant: 008310
type: Reaction
notes: SUBSYSTEM: Fatty acid degradation

004277
stoichiometry: 1.0
species: metaid M 223
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016137
stoichiometry: 1.0
species: metaid M 693
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102948
stoichiometry: 1.0
species: metaid M 793
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095215
stoichiometry: 1.0
species: metaid M 718
type: SpeciesReference

078272
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

133514
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid E 84
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is: S000000618
constant: false
type: Species
is: SBO:0000014
name: YCR024C
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in compartment: metaid C 2
notes: SHORT NAME: SLM5
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initial concentration: NaN
is: sce00252
boundary condition: false

114693
stoichiometry: 1.0
species: metaid M 795
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metaid M 501
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in compartment: metaid C 3
is: CHEBI:24636
name: H(+)
type: Species
initial concentration: NaN
constant: false
initial amount: NaN
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boundary condition: false

metaid E 424
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is: S000001635
notes: SHORT NAME: GPM1
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in compartment: metaid C 2
constant: false
type: Species
name: YKL152C
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is: sce00010
is: SBO:0000014
is: P00950

metaid R C160xtO
kinetic law: 133742
product: 133730
reactant: 133718
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of palmitic acid
type: Reaction

978035
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R FOX2 4
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fast: false
is: SBO:0000176
is: http://identifiers.org/ec-code/1.1.1.-
type: Reaction
reactant: 008201
reversible: false
reactant: 008189
kinetic law: 008249
name: D-3-hydroxyacyl-CoA dehydrogenase
product: 008213
notes: SUBSYSTEM: Fatty acid degradation
modifier: 008237

968549
stoichiometry: 1.0
species: metaid M 221
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020836
units: 958314
value: 0.0
type: LocalParameter

985709
stoichiometry: 1.0
species: metaid M 734
type: SpeciesReference

986538
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

021281
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

064578
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

055190
stoichiometry: 1.0
species: metaid M 340
type: SpeciesReference

024006
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

981826
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

136005
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species: metaid M 440
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020980
units: 958314
value: 0.69940502600246
type: LocalParameter

010910
stoichiometry: 1.0
species: metaid M 347
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970333
units: 958314
value: 0.046572045
type: LocalParameter

998630
units: 958314
value: 0.0
type: LocalParameter

122491
stoichiometry: 1.0
species: metaid M 1006
type: SpeciesReference

035301
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

132488
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

986478
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species: metaid M 469
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017378
stoichiometry: 1.0
species: metaid M 347
type: SpeciesReference

144193
stoichiometry: 0.231
species: metaid M 575
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047482
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value: 0.0
type: LocalParameter

043287
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R AONAxtO
kinetic law: 132644
product: 132632
reactant: 132620
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of 8-amino-7-oxononanoate
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107344
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

072876
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species: metaid M 874
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965324
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species: metaid M 660
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095191
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value: 0.0
type: LocalParameter

metaid R GAP1 21
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name: General amino-acid permease GAP1
reactant: 012415
modifier: 012439
fast: false
reversible: true
product: 012427
reactant: 012403
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kinetic law: 012451
type: Reaction

007983
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species: metaid M 689
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030317
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

021919
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

112801
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species: metaid M 253
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992490
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species: metaid M 539
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100058
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species: metaid M 592
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metaid R U81
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reactant: 102936
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kinetic law: 102984
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notes: SUBSYSTEM: Pyridoxine (vitamin B6) metabolism
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product: 102960
name: Pyridoxine kinase
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020209
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value: 0.0
type: LocalParameter

016437
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

051556
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value: 1000.0
name: UPPER_BOUND
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081889
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species: metaid M 578
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143321
stoichiometry: 0.51852
species: metaid M 485
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

986322
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid R GAP1 20
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type: Reaction
name: General amino-acid permease GAP1
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notes: SUBSYSTEM: Transport, extracellular
is: SBO:0000185
modifier: 012330
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product: 012318
reactant: 012294
kinetic law: 012342

138344
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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960803
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species: metaid M 453
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049724
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

973325
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species: metaid M 501
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966093
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species: metaid M 687
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106393
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species: metaid M 102
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

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species: metaid M 501
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072660
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species: metaid M 689
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131815
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

061867
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species: metaid M 116
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097830
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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016581
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species: metaid M 501
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086766
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species: metaid M 207
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007402
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value: 1000.0
name: UPPER_BOUND
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990578
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value: 0.04086069000001
type: LocalParameter

000351
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species: metaid M 218
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068642
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

983854
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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product: 132380
reactant: 132368
notes: SUBSYSTEM: Exchange reactions
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fast: false
reversible: false
name: Excretion of 5-aminolevulinate
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979333
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value: 0.0
type: LocalParameter

003457
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value: 0.0
type: LocalParameter

959943
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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species: metaid M 230
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140717
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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967059
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species: metaid M 698
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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species: metaid M 981
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992080
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value: 1000.0
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type: LocalParameter

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type: LocalParameter

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value: 0.0
name: OBJECTIVE_COEFFICIENT
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961082
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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102403
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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044505
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

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value: 0.0
name: OBJECTIVE_COEFFICIENT
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species: metaid M 923
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064819
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061289
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species: metaid M 408
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058070
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R MNTxtO
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reversible: false
name: Excretion of D-mannitol
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118945
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994138
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metaid E 642
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143092
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998846
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959602
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057902
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012965
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species: metaid M 501
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metaid R GIT1 2
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reactant: 014434
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type: Reaction
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969258
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087815
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metaid E 641
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044085
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101850
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978697
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034248
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072575
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070934
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090954
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085044
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139839
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142165
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052818
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metaid R GIT1 1
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product: 014350
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087924
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024690
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metaid R TKL2 1
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967168
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metaid R ECM40 2
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039946
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product: 104320
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073128
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is: SBO:0000014
initial amount: NaN
boundary condition: false
in compartment: metaid C 2

128213
units: 958314
value: 0.0
type: LocalParameter

128938
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

039380
units: 958314
value: 0.0
type: LocalParameter

974493
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

073959
stoichiometry: 1.0
species: metaid M 831
type: SpeciesReference

metaid R CRD1
product: 981886
type: Reaction
is: http://identifiers.org/ec-code/2.7.8.-
reversible: false
reactant: 981874
kinetic law: 981922
notes: SUBSYSTEM: Phospholipid biosynthesis
name: Cardiolipin synthetase
is: SBO:0000176
fast: false
modifier: 981910
product: 981898
reactant: 981862

993597
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 417
is: sce00530
in compartment: metaid C 2
constant: false
name: YKL104C
is: S000001587
notes: SHORT NAME: GFA1
type: Species
initial concentration: NaN
is: SBO:0000014
is: sce00251
has only substance units: false
boundary condition: false
is: P14742
initial amount: NaN

047171
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

994524
stoichiometry: 1.0
species: metaid M 694
type: SpeciesReference

043709
stoichiometry: 1.0
species: metaid M 187
type: SpeciesReference

139634
stoichiometry: 1.0
species: metaid M 717
type: SpeciesReference

983468
stoichiometry: 1.0
species: metaid M 239
type: SpeciesReference

metaid E 90
notes: SHORT NAME: ARE1
initial concentration: NaN
is: P25628
initial amount: NaN
in compartment: metaid C 2
has only substance units: false
name: YCR048W
type: Species
is: S000000644
boundary condition: false
constant: false
is: SBO:0000014

metaid R FUR1
reactant: 010033
is: http://identifiers.org/ec-code/2.4.2.9
kinetic law: 010081
name: Uracil phosphoribosyltransferase
type: Reaction
product: 010045
modifier: 010069
notes: SUBSYSTEM: Pyrimidine metabolism
reversible: false
product: 010057
fast: false
is: SBO:0000176
reactant: 010021

100755
stoichiometry: 1.0
species: metaid M 207
type: SpeciesReference

025099
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

073743
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

986550
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

121692
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

973421
units: 958314
value: 0.0
type: LocalParameter

metaid E 418
notes: SHORT NAME: AAT1
type: Species
initial amount: NaN
is: Q01802
is: S000001589
is: SBO:0000014
boundary condition: false
is: sce00350
in compartment: metaid C 2
initial concentration: NaN
is: sce00252
is: sce00272
is: sce00330
has only substance units: false
is: sce00251
constant: false
name: YKL106W
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is: sce00710
is: sce00400

961896
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R GLYxtI
kinetic law: 126231
product: 126219
reactant: 126207
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of glycine
type: Reaction

082925
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

032612
stoichiometry: 1.0
species: metaid M 82
type: SpeciesReference

021498
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

004132
units: 958314
value: 0.0
type: LocalParameter

metaid E 93
notes: SHORT NAME: GIT1
name: YCR098C
boundary condition: false
constant: false
is: S000000695
has only substance units: false
is: SBO:0000014
initial concentration: NaN
initial amount: NaN
type: Species
is: P25346
in compartment: metaid C 2

metaid R U95
is: http://identifiers.org/ec-code/2.7.7.3
name: Phospho-pantethiene adenylyltransferase
product: 104633
type: Reaction
kinetic law: 104645
notes: SUBSYSTEM: Pantothenate and CoA metabolism
reversible: false
product: 104621
fast: false
reactant: 104597
is: SBO:0000176
reactant: 104609

109530
units: 958314
value: 0.0
type: LocalParameter

076596
units: 958314
value: 0.0
type: LocalParameter

016885
units: 958314
value: 0.0
type: LocalParameter

045914
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 302
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notes: SHORT NAME: ARG4
has only substance units: false
boundary condition: false
is: P04076
name: YHR018C
initial concentration: NaN
type: Species
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constant: false
is: sce00252
is: sce00330
is: S000001060
is: sce00220
initial amount: NaN

080029
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

111457
stoichiometry: 1.0
species: metaid M 980
type: SpeciesReference

metaid E 415
notes: SHORT NAME: YNK1
initial amount: NaN
initial concentration: NaN
constant: false
name: YKL067W
has only substance units: false
is: S000001550
boundary condition: false
is: sce00230
is: P36010
is: SBO:0000014
type: Species
is: sce00240
in compartment: metaid C 2

978155
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

102803
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

057312
units: 958314
value: 0.0
type: LocalParameter

975589
stoichiometry: 1.0
species: metaid M 245
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094577
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

129899
units: 958314
value: 0.0
type: LocalParameter

959529
stoichiometry: 1.0
species: metaid M 575
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072213
units: 958314
value: 0.13452855000002
type: LocalParameter

139935
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

048446
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 92
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type: Species
in compartment: metaid C 2
initial concentration: NaN
is: S000000718
is: P37262
constant: false
has only substance units: false
is: SBO:0000014
notes: SHORT NAME: SOL2
boundary condition: false
is: sce00030
initial amount: NaN

132997
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

074907
stoichiometry: 1.0
species: metaid M 888
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979105
stoichiometry: 1.0
species: metaid M 509
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078767
stoichiometry: 1.0
species: metaid M 154
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134646
stoichiometry: 1.0
species: metaid M 328
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metaid E 303
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has only substance units: false
is: P38707
type: Species
in compartment: metaid C 2
is: sce00970
constant: false
notes: SHORT NAME: DED81
initial amount: NaN
boundary condition: false
name: YHR019C
is: S000001061
initial concentration: NaN
is: SBO:0000014

116081
stoichiometry: 1.0
species: metaid M 795
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metaid E 416
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is: P17505
is: sce00630
initial concentration: NaN
initial amount: NaN
in compartment: metaid C 2
is: sce00720
is: sce00710
boundary condition: false
is: sce00020
constant: false
notes: SHORT NAME: MDH1
is: sce00620
name: YKL085W
has only substance units: false
is: SBO:0000014
type: Species

981610
units: 958314
value: 0.05046775500001
type: LocalParameter

079655
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

118138
stoichiometry: 1.0
species: metaid M 698
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metaid E 95
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type: Species
initial amount: NaN
is: Q12008
is: S000002179
constant: false
initial concentration: NaN
boundary condition: false
is: SBO:0000014
notes: SHORT NAME: GPM2
is: sce00010
name: YDL021W
has only substance units: false

metaid R UAcyl 4 1
kinetic law: 105405
product: 105393
reactant: 105381
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Acyl-[acyl-carrier-protein] transporter, mitochondrial
type: Reaction

037746
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

094673
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

140207
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 413
notes: SHORT NAME: OAR1
is: P35731
initial concentration: NaN
is: SBO:0000014
type: Species
initial amount: NaN
name: YKL055C
has only substance units: false
in compartment: metaid C 2
boundary condition: false
constant: false
is: S000001538

metaid E 300
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is: S000001028
boundary condition: false
is: SBO:0000014
initial concentration: NaN
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name: YHL036W
is: P38734
type: Species
constant: false
notes: SHORT NAME: MUP3

091351
stoichiometry: 1.0
species: metaid M 501
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064264
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

047292
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

973638
units: 958314
value: 0.0
type: LocalParameter

050053
units: 958314
value: 0.0
type: LocalParameter

082805
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R PYRxtO
kinetic law: 140681
product: 140669
reactant: 140657
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of pyruvate
type: Reaction

064119
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

098010
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 639
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boundary condition: false
notes: SHORT NAME: NPT1
constant: false
type: Species
initial concentration: NaN
is: sce00760
is: SBO:0000014
has only substance units: false
name: YOR209C
initial amount: NaN
is: P39683
is: S000005735

135703
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 94
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notes: SHORT NAME: TSC13
has only substance units: false
in compartment: metaid C 2
initial concentration: NaN
is: Q99190
boundary condition: false
is: sce01040
type: Species
initial amount: NaN
name: YDL015C
is: S000002173
constant: false

993380
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

082384
stoichiometry: 1.0
species: metaid M 797
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031707
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

020666
stoichiometry: 4.0
species: metaid M 698
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108833
stoichiometry: 1.0
species: metaid M 324
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982757
stoichiometry: 1.0
species: metaid M 28
type: SpeciesReference

075463
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

050642
units: 958314
value: 0.08812361359969
type: LocalParameter

metaid E 301
is: P10614
is: SBO:0000014
notes: SHORT NAME: ERG11
is: S000001049
in compartment: metaid C 2
type: Species
is: sce00100
constant: false
boundary condition: false
initial concentration: NaN
initial amount: NaN
has only substance units: false
name: YHR007C

977061
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

046737
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

015712
units: 958314
value: 0.0
type: LocalParameter

012403
stoichiometry: 1.0
species: metaid M 501
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127552
stoichiometry: 1.0
species: metaid M 1066
type: SpeciesReference

992068
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

076294
stoichiometry: 1.0
species: metaid M 770
type: SpeciesReference

098757
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 414
notes: SHORT NAME: FBA1
is: SBO:0000014
initial concentration: NaN
in compartment: metaid C 2
is: sce00010
boundary condition: false
initial amount: NaN
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is: sce00030
is: sce00051
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has only substance units: false
name: YKL060C
is: P14540
is: S000001543
type: Species

040018
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

102912
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 306
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has only substance units: false
is: sce00330
type: Species
in compartment: metaid C 2
notes: SHORT NAME: PUT2
is: S000001079
constant: false
is: SBO:0000014
name: YHR037W
boundary condition: false
initial concentration: NaN
initial amount: NaN
is: P07275

141054
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R JEN1 1
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type: Reaction
modifier: 036528
product: 036516
name: Carboxylic acid transporter protein homolog
reversible: true
is: SBO:0000185
kinetic law: 036540
notes: SUBSYSTEM: Transport, extracellular
reactant: 036504
reactant: 036492

974805
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid E 411
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boundary condition: false
initial amount: NaN
is: P36013
type: Species
in compartment: metaid C 2
is: SBO:0000014
constant: false
notes: SHORT NAME: MAE1
has only substance units: false
is: sce00620
initial concentration: NaN
name: YKL029C

090534
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

048554
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

094469
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

118523
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

004241
units: 958314
value: 0.0
type: LocalParameter

027864
stoichiometry: 1.0
species: metaid M 245
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072369
stoichiometry: 1.0
species: metaid M 950
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983239
stoichiometry: 1.0
species: metaid M 230
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metaid E 97
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is: S000002198
name: YDL040C
is: P12945
type: Species
boundary condition: false
in compartment: metaid C 2
is: SBO:0000014
initial amount: NaN
notes: SHORT NAME: NAT1
constant: false
initial concentration: NaN

metaid E 307
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boundary condition: false
name: YHR042W
initial concentration: NaN
constant: false
is: SBO:0000014
is: S000001084
initial amount: NaN
notes: SHORT NAME: NCP1
has only substance units: false
type: Species
in compartment: metaid C 2

095949
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

111565
stoichiometry: 1.0
species: metaid M 215
type: SpeciesReference

078284
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R PPA2
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type: Reaction
modifier: 063445
reversible: false
notes: SUBSYSTEM: Oxidative phosphorylation
is: SBO:0000176
kinetic law: 063457
product: 063433
reactant: 063421
is: http://identifiers.org/ec-code/3.6.1.1

978047
units: 958314
value: 0.0
type: LocalParameter

metaid R U100
product: 084466
kinetic law: 084478
type: Reaction
product: 084454
reactant: 084442
is: http://identifiers.org/ec-code/1.4.3.16
reversible: false
is: SBO:0000176
fast: false
name: Quinolate synthase
reactant: 084430
notes: SUBSYSTEM: NAD biosynthesis

metaid R RFLAVxtI
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product: 129671
reactant: 129659
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of riboflavin
type: Reaction

080137
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 412
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is: P32861
initial amount: NaN
name: YKL035W
type: Species
notes: SHORT NAME: UGP1
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is: SBO:0000014
in compartment: metaid C 2
is: S000001518
initial concentration: NaN
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is: sce00052
is: sce00500
is: sce00040

metaid R JEN1 2
kinetic law: 036648
product: 036624
fast: false
reversible: true
reactant: 036600
notes: SUBSYSTEM: Transport, extracellular
modifier: 036636
name: Carboxylic acid transporter protein homolog
reactant: 036612
type: Reaction
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034164
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species: metaid M 38
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142249
units: 958314
value: 0.0
type: LocalParameter

037638
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species: metaid M 461
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metaid R CHS3
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modifier: 980067
type: Reaction
name: Chitin synthase 3
kinetic law: 980079
reversible: false
product: 980043
is: SBO:0000176
notes: SUBSYSTEM: Glutamate metabolism (aminosugars metabolism)
is: http://identifiers.org/ec-code/2.4.1.16
fast: false
product: 980055

114681
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species: metaid M 612
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metaid R COX1
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kinetic law: 981285
fast: false
notes: SUBSYSTEM: Oxidative phosphorylation
is: http://identifiers.org/ec-code/1.9.3.1
reactant: 981249
reactant: 981225
product: 981261
reversible: false
name: Cytochrome c oxidase subunit 1
type: Reaction
is: SBO:0000176
reactant: 981237

064831
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

095203
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species: metaid M 287
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metaid R NPT1 2
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is: SBO:0000176
product: 049676
type: Reaction
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notes: SUBSYSTEM: Nicotinic acid synthesis from TRP
product: 049664
reversible: false
modifier: 049688
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initial concentration: NaN
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type: Species
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is: SBO:0000014
initial amount: NaN

019414
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species: metaid M 461
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973747
units: 958314
value: 0.0
type: LocalParameter

098649
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 304
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is: SBO:0000014
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initial concentration: NaN
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123851
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species: metaid M 368
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065649
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species: metaid M 356
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115235
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species: metaid M 491
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078875
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species: metaid M 262
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metaid R STT4
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is: http://identifiers.org/ec-code/2.7.1.67
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is: SBO:0000176
fast: false
reactant: 075620
product: 075644
notes: SUBSYSTEM: Phospholipid biosynthesis
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reactant: 075608
kinetic law: 075668
modifier: 075656
product: 075632

964648
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value: 0.0
type: LocalParameter

062060
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

031815
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 99
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constant: false
is: S000002210
notes: SHORT NAME: SLC1
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type: Species
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product: 049544
kinetic law: 049580
is: http://identifiers.org/ec-code/2.4.2.11
is: SBO:0000176
name: Nicotinate phosphoribosyltransferase
type: Reaction
notes: SUBSYSTEM: NAD biosynthesis
reactant: 049532
modifier: 049568
product: 049556
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reversible: false

133394
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species: metaid M 1004
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101548
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 305
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initial concentration: NaN
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is: SBO:0000014
name: YHR025W
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notes: SHORT NAME: THR1
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metaid E 410
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initial concentration: NaN
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has only substance units: false
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boundary condition: false

968773
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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097818
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

050751
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid R U115
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product: 085851
reactant: 085839
notes: SUBSYSTEM: Transport, mitochondrial
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reversible: true
name: Transport of 5,10-methylenetetrahydrofolate, mitochondrial
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140922
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species: metaid M 1093
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144168
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species: metaid M 562
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989359
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value: 1000.0
name: UPPER_BOUND
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metaid E 98
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notes: SHORT NAME: FAD1
type: Species
is: SBO:0000014
is: P38913
constant: false
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initial amount: NaN
boundary condition: false
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011318
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species: metaid M 501
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111130
units: 958314
value: 0.0
name: LOWER_BOUND
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982092
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species: metaid M 463
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054336
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

958371
stoichiometry: 1.0
species: metaid M 263
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metaid R PYRxtI
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product: 129587
reactant: 129575
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of pyruvate
type: Reaction

081658
units: 958314
value: 0.00227867250019
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029195
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value: 0.89012300739788
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994752
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value: 0.08812361359969
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026590
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080791
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species: metaid M 38
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982649
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value: 0.17188743000026
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139863
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
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049955
units: 958314
value: 0.0
type: LocalParameter

metaid R ADE3 3
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kinetic law: 961738
reversible: true
reactant: 961702
is: http://identifiers.org/ec-code/3.5.4.9
type: Reaction
modifier: 961726
product: 961714
notes: SUBSYSTEM: One carbon pool by folate
fast: false

006437
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species: metaid M 58
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072008
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species: metaid M 613
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989903
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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103584
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value: 0.0
type: LocalParameter

025231
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species: metaid M 230
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134068
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species: metaid M 1012
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061108
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

083758
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value: 1000.0
name: UPPER_BOUND
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983022
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species: metaid M 698
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110071
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value: -1000.0
name: LOWER_BOUND
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007815
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094997
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value: 0.0
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970561
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species: metaid M 92
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143575
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species: metaid M 633
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981069
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047062
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species: metaid M 617
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metaid E 308
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in compartment: metaid C 2
type: Species
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constant: false
initial amount: NaN
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993440
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species: metaid M 441
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969971
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid R FUR4
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product: 010165
name: Uracil permease
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modifier: 010177
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notes: SUBSYSTEM: Transport, extracellular
fast: false
is: SBO:0000185
type: Reaction
reversible: false

063336
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species: metaid M 892
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071055
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species: metaid M 221
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metaid R ADE3 1
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reactant: 961448
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type: Reaction
product: 961472
notes: SUBSYSTEM: One carbon pool by folate
kinetic law: 961496
product: 961460

097518
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value: 0.0
name: LOWER_BOUND
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modifier: 979958
type: Reaction
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kinetic law: 979970
fast: false
is: SBO:0000176
notes: SUBSYSTEM: Glutamate metabolism (aminosugars metabolism)
product: 979934
reactant: 979922

984985
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species: metaid M 874
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117499
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value: 1000.0
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079233
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species: metaid M 179
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005629
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value: 0.0
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032503
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species: metaid M 590
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110299
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value: 1000.0
name: UPPER_BOUND
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initial amount: NaN
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value: 0.0
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species: metaid M 529
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128105
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value: 0.0
name: UPPER_BOUND
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metaid R ADE3 2
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notes: SUBSYSTEM: One carbon pool by folate
is: SBO:0000176
modifier: 961630
kinetic law: 961642
reactant: 961568
name: Formyltetrahydrofolate synthetase
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fast: false
product: 961617
reactant: 961580
type: Reaction
product: 961592
product: 961604
is: http://identifiers.org/ec-code/6.3.4.3

060904
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species: metaid M 688
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069268
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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068437
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961472
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species: metaid M 693
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metaid R CHS1
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kinetic law: 979862
type: Reaction
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modifier: 979850
product: 979838
reactant: 979814
notes: SUBSYSTEM: Glutamate metabolism (aminosugars metabolism)
product: 979826
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048337
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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085128
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086249
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119633
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062493
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species: metaid M 891
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962198
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value: 0.04229004000001
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043589
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species: metaid M 187
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product: 006256
reactant: 006243
notes: SUBSYSTEM: Other
is: SBO:0000176
fast: false
reversible: false
name: Model-specific reaction, used to affect NADPH levels by converting NADP+ to NADPH
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107972
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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constant: false
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969390
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value: 1000.0
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057938
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

998810
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

984203
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species: metaid M 371
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metaid E 630
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994102
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species: metaid M 768
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046953
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120707
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species: metaid M 693
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096431
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value: 1000.0
name: UPPER_BOUND
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species: metaid M 463
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103068
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species: metaid M 230
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109687
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species: metaid M 230
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034236
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041388
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species: metaid M 84
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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species: metaid M 689
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001939
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value: 1000.0
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101886
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121233
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species: metaid M 235
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value: -1000.0
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species: metaid M 327
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notes: SUBSYSTEM: Transport, extracellular
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139719
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species: metaid M 727
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961070
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value: 1000.0
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967023
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species: metaid M 403
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057794
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species: metaid M 501
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product: 013736
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metaid E 523
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species: metaid M 262
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994608
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value: 1000.0
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959955
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value: 0.7564755118464
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metaid R RFLAVxtO
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product: 140753
reactant: 140741
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
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reversible: false
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metaid R U80
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reversible: false
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kinetic law: 102876
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notes: SUBSYSTEM: Riboflavin metabolism
reactant: 102839
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073008
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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118307
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value: 1000.0
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111782
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species: metaid M 592
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product: 125283
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reversible: false
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077537
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value: -1000.0
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102415
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962343
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120115
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species: metaid M 318
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979934
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species: metaid M 307
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species: metaid M 448
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value: 0.0
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081877
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species: metaid M 311
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has only substance units: false
is: P06633
is: SBO:0000014

994307
stoichiometry: 1.0
species: metaid M 278
type: SpeciesReference

072996
stoichiometry: 1.0
species: metaid M 873
type: SpeciesReference

962453
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

013590
stoichiometry: 1.0
species: metaid M 484
type: SpeciesReference

976905
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

086646
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

035541
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

990698
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R GAP1 12
notes: SUBSYSTEM: Transport, extracellular
reversible: true
name: General amino-acid permease GAP1
is: SBO:0000185
fast: false
kinetic law: 011366
type: Reaction
modifier: 011354
reactant: 011330
reactant: 011318
product: 011342

138489
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

018617
stoichiometry: 1.0
species: metaid M 29
type: SpeciesReference

000556
units: 958314
value: 0.08812361359972
type: LocalParameter

124068
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

030439
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

133286
units: 958314
value: 0.39
type: LocalParameter

972023
stoichiometry: 1.0
species: metaid M 534
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metaid E 637
is: Q08579
initial concentration: NaN
is: SBO:0000014
initial amount: NaN
name: YOR192C
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type: Species
in compartment: metaid C 2
notes: SHORT NAME: THI72
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has only substance units: false
boundary condition: false

036492
stoichiometry: 1.0
species: metaid M 501
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055070
stoichiometry: 1.0
species: metaid M 266
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112945
stoichiometry: 1.0
species: metaid M 254
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960925
stoichiometry: 1.0
species: metaid M 873
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983999
stoichiometry: 1.0
species: metaid M 321
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099397
units: 958314
value: 0.0
type: LocalParameter

095721
units: 958314
value: 0.0
type: LocalParameter

metaid R GAP1 11
is: SBO:0000185
fast: false
reactant: 011222
notes: SUBSYSTEM: Transport, extracellular
kinetic law: 011258
reversible: true
name: General amino-acid permease GAP1
reactant: 011210
product: 011234
type: Reaction
modifier: 011246

969173
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species: metaid M 263
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998750
stoichiometry: 1.0
species: metaid M 915
type: SpeciesReference

986659
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 636
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has only substance units: false
initial concentration: NaN
name: YOR190W
is: sce00500
is: SBO:0000014
is: S000005716
initial amount: NaN
boundary condition: false
is: P32603
constant: false
type: Species
notes: SHORT NAME: SPR1

043167
units: 958314
value: 0.83520186750002
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064699
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

136812
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

054228
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

035975
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

090642
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

983686
stoichiometry: 1.0
species: metaid M 488
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971095
stoichiometry: 1.0
species: metaid M 562
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097974
stoichiometry: 1.0
species: metaid M 979
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139416
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

042485
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R GAP1 14
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notes: SUBSYSTEM: Transport, extracellular
reactant: 011535
is: SBO:0000185
product: 011559
reactant: 011547
type: Reaction
name: General amino-acid permease GAP1
kinetic law: 011583
modifier: 011571
fast: false

020714
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

050305
stoichiometry: 1.0
species: metaid M 694
type: SpeciesReference

137176
units: 958314
value: 0.0
type: LocalParameter

metaid E 635
is: P33330
notes: SHORT NAME: SER1
initial concentration: NaN
name: YOR184W
is: SBO:0000014
initial amount: NaN
in compartment: metaid C 2
has only substance units: false
type: Species
constant: false
boundary condition: false
is: S000005710

968405
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

007222
units: 958314
value: 0.0
type: LocalParameter

metaid R FBA1
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kinetic law: 003758
reactant: 003710
modifier: 003746
reversible: true
is: SBO:0000176
product: 003734
type: Reaction
notes: SUBSYSTEM: Glycolysis / Gluconeogenesis
fast: false
is: http://identifiers.org/ec-code/4.1.2.13
name: Fructose-bisphosphate aldolase

056554
stoichiometry: 3.0
species: metaid M 733
type: SpeciesReference

977602
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

093195
units: 958314
value: 0.0
type: LocalParameter

037023
stoichiometry: 1.0
species: metaid M 599
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metaid R GAP1 13
reactant: 011438
kinetic law: 011475
reversible: true
notes: SUBSYSTEM: Transport, extracellular
fast: false
product: 011451
type: Reaction
reactant: 011426
name: General amino-acid permease GAP1
is: SBO:0000185
modifier: 011463

087487
units: 958314
value: 2.86596484969523
type: LocalParameter

999798
stoichiometry: 1.0
species: metaid M 218
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120007
stoichiometry: 1.0
species: metaid M 770
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metaid E 521
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in compartment: metaid C 2
has only substance units: false
initial amount: NaN
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is: sce00564
is: S000004608
notes: SHORT NAME: PLB2
initial concentration: NaN
type: Species
boundary condition: false
is: SBO:0000014
name: YMR006C

040126
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 634
in compartment: metaid C 2
constant: false
type: Species
is: S000005706
boundary condition: false
notes: SHORT NAME: DCI1
is: SBO:0000014
initial amount: NaN
initial concentration: NaN
name: YOR180C
has only substance units: false
is: Q08558

965444
stoichiometry: 1.0
species: metaid M 606
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077645
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

115018
stoichiometry: 1.0
species: metaid M 331
type: SpeciesReference

973859
units: 958314
value: 0.0
type: LocalParameter

065781
stoichiometry: 1.0
species: metaid M 784
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101994
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

118415
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R GAP1 16
kinetic law: 011800
reversible: true
is: SBO:0000185
reactant: 011752
modifier: 011788
notes: SUBSYSTEM: Transport, extracellular
reactant: 011764
type: Reaction
product: 011776
name: General amino-acid permease GAP1
fast: false

968331
stoichiometry: 1.0
species: metaid M 333
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073116
stoichiometry: 1.0
species: metaid M 221
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985937
units: 958314
value: 0.0
type: LocalParameter

028798
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

128550
units: 958314
value: 0.0
type: LocalParameter

079727
stoichiometry: 1.0
species: metaid M 230
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metaid E 520
is: sce00650
name: YML126C
is: SBO:0000014
initial concentration: NaN
constant: false
in compartment: metaid C 2
is: sce00280
is: P54839
has only substance units: false
boundary condition: false
initial amount: NaN
notes: SHORT NAME: ERG13
is: S000004595
type: Species
is: sce00072

metaid E 633
is: P16622
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is: SBO:0000014
has only substance units: false
is: S000005702
constant: false
notes: SHORT NAME: HEM15
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name: YOR176W
initial amount: NaN
initial concentration: NaN

978552
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

043697
stoichiometry: 1.0
species: metaid M 694
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111675
stoichiometry: 1.0
species: metaid M 299
type: SpeciesReference

998968
units: 958314
value: 5.33880676E-5
type: LocalParameter

969282
units: 958314
value: 0.05295810000003
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016173
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

970417
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

959748
units: 958314
value: 0.32688552000008
type: LocalParameter

020449
stoichiometry: 1.0
species: metaid M 780
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metaid R GAP1 15
modifier: 011680
reversible: true
fast: false
notes: SUBSYSTEM: Transport, extracellular
is: SBO:0000185
reactant: 011656
reactant: 011644
product: 011668
type: Reaction
kinetic law: 011692
name: General amino-acid permease GAP1

141333
stoichiometry: 1.0
species: metaid M 854
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096588
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

142044
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

052939
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

003578
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 632
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initial amount: NaN
is: Q12246
has only substance units: false
is: SBO:0000014
is: sce00600
notes: SHORT NAME: LCB4
name: YOR171C
constant: false
initial concentration: NaN
type: Species
boundary condition: false
in compartment: metaid C 2

111022
units: 958314
value: 0.0
type: LocalParameter

044649
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

106273
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

064939
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R U185
notes: SUBSYSTEM: Transport, extracellular
kinetic law: 092264
product: 092252
reversible: false
is: SBO:0000185
type: Reaction
reactant: 092228
fast: false
name: Transport of adenosine, extracellular
reactant: 092240

035757
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

106116
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R GAP1 18
name: General amino-acid permease GAP1
reactant: 011982
reactant: 011970
fast: false
type: Reaction
notes: SUBSYSTEM: Transport, extracellular
reversible: true
is: SBO:0000185
product: 011994
kinetic law: 012018
modifier: 012006

metaid E 631
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initial amount: NaN
boundary condition: false
is: S000005694
is: SBO:0000014
is: sce00970
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in compartment: metaid C 2
is: P13188
type: Species
is: sce00251
name: YOR168W
initial concentration: NaN
has only substance units: false

963273
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

984311
stoichiometry: 1.0
species: metaid M 903
type: SpeciesReference

979213
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

081769
units: 958314
value: 0.0
type: LocalParameter

046893
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 1100
is: SBO:0000299
initial concentration: NaN
has only substance units: false
type: Species
initial amount: NaN
name: succinate
boundary condition: true
in compartment: metaid C 4
is: CHEBI:30031
constant: false

001710
units: 958314
value: 0.0
type: LocalParameter

000652
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

048229
units: 958314
value: 0.0
type: LocalParameter

126952
units: 958314
value: 0.0
type: LocalParameter

127985
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species: metaid M 663
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091915
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

133971
stoichiometry: 1.0
species: metaid M 288
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086139
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

058191
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R U73
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is: SBO:0000176
reactant: 102055
name: ThiE protein
product: 102091
type: Reaction
fast: false
reactant: 102031
reversible: false
kinetic law: 102103
product: 102067
product: 102079
notes: SUBSYSTEM: Thiamine (vitamin B1) metabolism

metaid R GAP1 17
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product: 011885
modifier: 011897
name: General amino-acid permease GAP1
is: SBO:0000185
reactant: 011860
reactant: 011873
kinetic law: 011909
type: Reaction
notes: SUBSYSTEM: Transport, extracellular
reversible: true

039910
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

128225
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species: metaid M 1074
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039392
stoichiometry: 1.0
species: metaid M 70
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063433
stoichiometry: 2.0
species: metaid M 734
type: SpeciesReference

974481
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

083322
stoichiometry: 1.0
species: metaid M 893
type: SpeciesReference

metaid R MVD1
product: 047975
product: 048011
type: Reaction
notes: SUBSYSTEM: Sterol biosynthesis
product: 047987
reactant: 047963
kinetic law: 048035
name: Diphosphomevalonate decarboxylase
product: 047999
reversible: false
is: SBO:0000176
is: http://identifiers.org/ec-code/4.1.1.33
modifier: 048023
fast: false
reactant: 047951

117378
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R YAT1
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name: Putative mitochondrial carnitine O-acetyltransferase
product: 111565
reactant: 111541
is: SBO:0000176
product: 111577
kinetic law: 111601
is: http://identifiers.org/ec-code/2.3.1.7
notes: SUBSYSTEM: Alanine and aspartate metabolism
modifier: 111589
type: Reaction
reversible: false
reactant: 111553

973529
units: 958314
value: 0.0
type: LocalParameter

metaid M 1104
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has only substance units: false
boundary condition: true
is: SBO:0000299
initial concentration: NaN
initial amount: NaN
constant: false
is: CHEBI:17821
name: thymine
type: Species

127420
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

994536
stoichiometry: 1.0
species: metaid M 922
type: SpeciesReference

047183
units: 958314
value: 0.0
type: LocalParameter

974336
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species: metaid M 601
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metaid E 405
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is: S000003921
is: P47186
notes: SHORT NAME: MPH3
has only substance units: false
type: Species
initial concentration: NaN
is: SBO:0000014
boundary condition: false
initial amount: NaN
in compartment: metaid C 2
name: YJR160C

993585
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

095829
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species: metaid M 226
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998981
stoichiometry: 1.0
species: metaid M 406
type: SpeciesReference

metaid R ACH1
product: 959772
name: Acetyl-CoA hydrolase
modifier: 959797
kinetic law: 959809
fast: false
product: 959784
is: http://identifiers.org/ec-code/3.1.2.1
is: SBO:0000176
reversible: false
reactant: 959760
type: Reaction
notes: SUBSYSTEM: Pyruvate metabolism

100767
stoichiometry: 1.0
species: metaid M 453
type: SpeciesReference

986562
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

073755
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species: metaid M 786
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983456
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species: metaid M 240
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139646
stoichiometry: 1.0
species: metaid M 1078
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053770
units: 958314
value: 0.0
type: LocalParameter

004579
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species: metaid M 234
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032624
stoichiometry: 1.0
species: metaid M 699
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122479
units: 958314
value: 0.0
type: LocalParameter

metaid R YAT2
product: 111686
is: http://identifiers.org/ec-code/2.3.1.-
kinetic law: 111722
name: Carnitine acetyltransferase
reactant: 111662
modifier: 111710
is: SBO:0000176
reversible: false
fast: false
notes: SUBSYSTEM: Fatty acid biosynthesis
reactant: 111675
product: 111698
type: Reaction

052951
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

999449
stoichiometry: 1.0
species: metaid M 867
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082913
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 1103
type: Species
initial concentration: NaN
in compartment: metaid C 4
name: L-threonine
is: CHEBI:16857
has only substance units: false
boundary condition: true
is: SBO:0000299
initial amount: NaN
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025087
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species: metaid M 245
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metaid E 406
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is: S000001484
is: sce00920
has only substance units: false
type: Species
is: SBO:0000014
initial amount: NaN
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is: sce00450
notes: SHORT NAME: MET14
is: Q02196
name: YKL001C
constant: false
initial concentration: NaN

000327
units: 958314
value: 0.08296592527666
type: LocalParameter

110191
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

026300
units: 958314
value: 0.0
type: LocalParameter

metaid R TGL2
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fast: false
reversible: false
is: SBO:0000176
reactant: 078308
product: 078332
notes: SUBSYSTEM: Glycerol metabolism (glycerolipid metabolism)
product: 078320
name: Lipase 2
is: http://identifiers.org/ec-code/3.1.1.3
modifier: 078345
type: Reaction

133694
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

975432
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R HXT3 2
notes: SUBSYSTEM: Transport, extracellular
reactant: 028244
modifier: 028268
type: Reaction
fast: false
kinetic law: 028280
name: High-affinity hexose transporter HXT6
reversible: false
is: SBO:0000185
product: 028256

091591
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R U19
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product: 092750
product: 092738
is: SBO:0000176
notes: SUBSYSTEM: Salvage pathways
reactant: 092726
type: Reaction
is: http://identifiers.org/ec-code/2.7.4.11
kinetic law: 092762
reactant: 092714
reversible: true

026493
units: 958314
value: 0.0
type: LocalParameter

metaid E 407
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is: S000001487
boundary condition: false
constant: false
notes: SHORT NAME: AUR1
initial concentration: NaN
is: P36107
name: YKL004W
initial amount: NaN
is: SBO:0000014
type: Species
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metaid M 1102
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constant: false
name: thiamin
initial concentration: NaN
type: Species
has only substance units: false
is: SBO:0000299
in compartment: metaid C 4
initial amount: NaN
boundary condition: true

metaid R TGL1
kinetic law: 078248
type: Reaction
modifier: 078236
product: 078212
product: 078224
is: http://identifiers.org/ec-code/3.1.1.13
notes: SUBSYSTEM: Sterol biosynthesis
is: SBO:0000176
fast: false
name: Sterol esterase TGL1
reversible: false
reactant: 078200

024294
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

006317
units: 958314
value: 0.0
type: LocalParameter

084187
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species: metaid M 624
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984841
stoichiometry: 1.0
species: metaid M 356
type: SpeciesReference

127312
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species: metaid M 632
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metaid R HXT3 1
is: SBO:0000185
product: 028160
type: Reaction
reactant: 028148
kinetic law: 028184
name: High-affinity hexose transporter HXT6
notes: SUBSYSTEM: Transport, extracellular
fast: false
modifier: 028172
reversible: false

081538
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value: 0.00911469000001
type: LocalParameter

073815
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

054432
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species: metaid M 790
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metaid M 1101
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initial amount: NaN
boundary condition: true
initial concentration: NaN
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constant: false
name: sucrose
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metaid E 408
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type: Species
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notes: SHORT NAME: LAC1
is: P28496
is: S000001491
initial concentration: NaN

094685
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species: metaid M 453
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metaid R TGL4
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reversible: false
is: SBO:0000176
modifier: 078562
notes: SUBSYSTEM: Glycerol metabolism (glycerolipid metabolism)
is: http://identifiers.org/ec-code/3.1.1.3
product: 078550
product: 078537
name: Lipase 4
kinetic law: 078574
reactant: 078525
type: Reaction

037734
stoichiometry: 1.0
species: metaid M 852
type: SpeciesReference

098022
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

050065
stoichiometry: 1.0
species: metaid M 735
type: SpeciesReference

064107
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

082817
units: 958314
value: 0.04092854999999
type: LocalParameter

989479
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 627
notes: SHORT NAME: ADE2
in compartment: metaid C 2
boundary condition: false
constant: false
is: P21264
is: sce00230
is: S000005654
type: Species
name: YOR128C
has only substance units: false
initial concentration: NaN
initial amount: NaN
is: SBO:0000014

metaid M 1108
type: Species
name: uracil
in compartment: metaid C 4
has only substance units: false
initial amount: NaN
is: CHEBI:17568
boundary condition: true
is: SBO:0000299
constant: false
initial concentration: NaN

metaid E 401
is: S000003909
is: sce00770
initial concentration: NaN
initial amount: NaN
is: SBO:0000014
type: Species
is: P47176
is: sce00280
is: sce00290
name: YJR148W
has only substance units: false
in compartment: metaid C 2
boundary condition: false
constant: false
notes: SHORT NAME: BAT2

091363
stoichiometry: 1.0
species: metaid M 536
type: SpeciesReference

064252
units: 958314
value: 0.0
type: LocalParameter

050630
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

963117
stoichiometry: 2.0
species: metaid M 230
type: SpeciesReference

metaid R HXT3 3
notes: SUBSYSTEM: Transport, extracellular
type: Reaction
kinetic law: 028376
modifier: 028364
name: High-affinity hexose transporter HXT6
fast: false
reversible: false
reactant: 028340
product: 028352
is: SBO:0000185

995090
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

031719
units: 958314
value: 0.0
type: LocalParameter

metaid R TGL3
type: Reaction
name: Lipase 3
reactant: 078417
notes: SUBSYSTEM: Glycerol metabolism (glycerolipid metabolism)
modifier: 078453
is: SBO:0000176
kinetic law: 078465
product: 078441
fast: false
product: 078429
reversible: false
is: http://identifiers.org/ec-code/3.1.1.3

108845
stoichiometry: 1.0
species: metaid M 575
type: SpeciesReference

020654
stoichiometry: 1.0
species: metaid M 520
type: SpeciesReference

metaid R UAcyl 3 1
kinetic law: 105321
product: 105309
reactant: 105297
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Acyl-[acyl-carrier-protein] transporter, mitochondrial
type: Reaction

982745
units: 958314
value: 0.0
type: LocalParameter

015724
stoichiometry: 1.0
species: metaid M 83
type: SpeciesReference

138693
units: 958314
value: 0.0
type: LocalParameter

076282
stoichiometry: 1.0
species: metaid M 691
type: SpeciesReference

metaid E 628
constant: false
type: Species
has only substance units: false
initial amount: NaN
is: SBO:0000014
notes: SHORT NAME: ORT1
name: YOR130C
is: Q12375
boundary condition: false
is: S000005656
in compartment: metaid C 2
initial concentration: NaN

098745
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

047392
stoichiometry: 1.0
species: metaid M 626
type: SpeciesReference

119089
stoichiometry: 1.0
species: metaid M 414
type: SpeciesReference

metaid E 402
initial amount: NaN
boundary condition: false
is: SBO:0000014
type: Species
notes: SHORT NAME: DAL5
has only substance units: false
in compartment: metaid C 2
initial concentration: NaN
constant: false
is: P15365
is: S000003913
name: YJR152W

metaid M 1107
type: Species
is: CHEBI:17895
in compartment: metaid C 4
has only substance units: false
initial amount: NaN
initial concentration: NaN
boundary condition: true
is: SBO:0000299
name: L-tyrosine
constant: false

111831
stoichiometry: 1.0
species: metaid M 691
type: SpeciesReference

127540
units: 958314
value: 0.0
type: LocalParameter

020005
stoichiometry: 1.0
species: metaid M 185
type: SpeciesReference

095492
stoichiometry: 1.0
species: metaid M 733
type: SpeciesReference

109542
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

076584
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

118644
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

021486
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

978167
units: 958314
value: 0.00246441000001
type: LocalParameter

metaid E 629
is: sce00640
name: YOR142W
is: S000005668
notes: SHORT NAME: LSC1
constant: false
in compartment: metaid C 2
boundary condition: false
is: sce00020
is: sce00720
type: Species
initial amount: NaN
is: SBO:0000014
initial concentration: NaN
is: sce00660
is: P53598
has only substance units: false

metaid E 403
notes: SHORT NAME: HXT16
initial amount: NaN
is: S000003919
constant: false
initial concentration: NaN
is: P47185
has only substance units: false
boundary condition: false
name: YJR158W
is: SBO:0000014
type: Species
in compartment: metaid C 2

975577
stoichiometry: 1.0
species: metaid M 29
type: SpeciesReference

057324
stoichiometry: 1.0
species: metaid M 636
type: SpeciesReference

004144
stoichiometry: 1.0
species: metaid M 331
type: SpeciesReference

968895
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid M 1106
in compartment: metaid C 4
name: L-tryptophan
initial amount: NaN
constant: false
has only substance units: false
is: SBO:0000299
boundary condition: true
type: Species
is: CHEBI:16828
initial concentration: NaN

028690
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

016897
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

048458
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

095348
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

121092
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid R TGL5
product: 078646
type: Reaction
fast: false
is: SBO:0000176
notes: SUBSYSTEM: Glycerol metabolism (glycerolipid metabolism)
modifier: 078671
reversible: false
name: Lipase 5
reactant: 078634
is: http://identifiers.org/ec-code/3.1.1.3
kinetic law: 078683
product: 078658

094565
stoichiometry: 1.0
species: metaid M 315
type: SpeciesReference

968561
stoichiometry: 1.0
species: metaid M 429
type: SpeciesReference

072225
stoichiometry: 1.0
species: metaid M 147
type: SpeciesReference

139923
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

035529
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

959517
stoichiometry: 1.0
species: metaid M 155
type: SpeciesReference

116093
stoichiometry: 1.0
species: metaid M 965
type: SpeciesReference

metaid E 404
constant: false
is: S000003920
has only substance units: false
notes: SHORT NAME: SOR1
is: sce00051
is: P35497
name: YJR159W
is: SBO:0000014
type: Species
in compartment: metaid C 2
initial concentration: NaN
boundary condition: false
initial amount: NaN

981622
stoichiometry: 1.0
species: metaid M 303
type: SpeciesReference

028096
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

102816
units: 958314
value: 0.0
type: LocalParameter

123502
stoichiometry: 1.0
species: metaid M 1018
type: SpeciesReference

metaid M 1105
name: alpha,alpha-trehalose
in compartment: metaid C 4
initial concentration: NaN
initial amount: NaN
constant: false
has only substance units: false
is: SBO:0000299
boundary condition: true
type: Species
is: CHEBI:16551

079667
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

078779
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

134658
stoichiometry: 1.0
species: metaid M 1019
type: SpeciesReference

metaid R U170
kinetic law: 090714
product: 090702
reactant: 090690
notes: SUBSYSTEM: Transport, extracellular
is: SBO:0000185
fast: false
reversible: true
name: Transport of D-xylose, extracellular
type: Reaction

078887
stoichiometry: 1.0
species: metaid M 71
type: SpeciesReference

973759
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

metaid R CEM1 2
modifier: 978372
product: 978336
fast: false
product: 978360
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
is: SBO:0000176
type: Reaction
product: 978348
reversible: false
kinetic law: 978384
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog
reactant: 978312
is: http://identifiers.org/ec-code/2.3.1.41
reactant: 978324

079438
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

098637
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

115247
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

metaid E 518
constant: false
initial amount: NaN
is: SBO:0000014
is: P32340
notes: SHORT NAME: NDI1
name: YML120C
is: sce00190
type: Species
has only substance units: false
initial concentration: NaN
in compartment: metaid C 2
is: S000004589
boundary condition: false

065637
units: 958314
value: 0.00525027749995
type: LocalParameter

085284
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R RPE1
reactant: 069893
kinetic law: 069929
notes: SUBSYSTEM: Pentose phosphate pathway
reversible: true
product: 069905
is: SBO:0000176
modifier: 069917
name: Ribulose-phosphate 3-epimerase
type: Reaction
fast: false
is: http://identifiers.org/ec-code/5.1.3.1

972893
stoichiometry: 1.0
species: metaid M 424
type: SpeciesReference

064951
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

031827
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

037625
stoichiometry: 1.0
species: metaid M 1
type: SpeciesReference

964636
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

097806
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R HXT17 1
fast: false
notes: SUBSYSTEM: Transport, extracellular
name: Hexose transporter HXT17
modifier: 027587
is: SBO:0000185
kinetic law: 027599
reactant: 027563
type: Reaction
product: 027575
reversible: false

123707
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

961678
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

111988
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R CEM1 1
is: SBO:0000176
type: Reaction
product: 978227
modifier: 978240
reactant: 978179
product: 978203
reactant: 978191
reversible: false
kinetic law: 978252
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
is: http://identifiers.org/ec-code/2.3.1.41
product: 978215
fast: false

016269
stoichiometry: 1.0
species: metaid M 693
type: SpeciesReference

998606
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 519
is: P25297
constant: false
initial amount: NaN
is: SBO:0000014
in compartment: metaid C 2
notes: SHORT NAME: PHO84
name: YML123C
initial concentration: NaN
is: S000004592
type: Species
boundary condition: false
has only substance units: false

000219
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

140910
stoichiometry: 1.0
species: metaid M 826
type: SpeciesReference

108736
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

133382
stoichiometry: 1.0
species: metaid M 280
type: SpeciesReference

094793
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

141066
units: 958314
value: 0.0
type: LocalParameter

968786
units: 958314
value: 1.5834000004E-4
type: LocalParameter

metaid R HXT17 2
name: Hexose transporter HXT17
modifier: 027683
reversible: false
reactant: 027659
fast: false
kinetic law: 027695
is: SBO:0000185
type: Reaction
product: 027671
notes: SUBSYSTEM: Transport, extracellular

028581
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

102924
units: 958314
value: 0.0
type: LocalParameter

metaid R CEM1 4
product: 978624
fast: false
reactant: 978588
reactant: 978576
kinetic law: 978649
modifier: 978637
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
product: 978612
is: SBO:0000176
type: Reaction
is: http://identifiers.org/ec-code/2.3.1.41
product: 978600
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog
reversible: false

094457
units: 958314
value: 0.0
type: LocalParameter

118535
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R FUMxtO
kinetic law: 136367
product: 136355
reactant: 136343
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of fumarate
type: Reaction

004253
stoichiometry: 1.0
species: metaid M 234
type: SpeciesReference

126724
stoichiometry: 1.0
species: metaid M 514
type: SpeciesReference

090546
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

048566
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

073188
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

127696
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R HXT17 3
kinetic law: 027791
name: Hexose transporter HXT17
reactant: 027755
modifier: 027779
notes: SUBSYSTEM: Transport, extracellular
is: SBO:0000185
fast: false
reversible: false
type: Reaction
product: 027767

metaid E 400
type: Species
in compartment: metaid C 2
initial concentration: NaN
notes: SHORT NAME: PMT4
constant: false
boundary condition: false
is: SBO:0000014
has only substance units: false
name: YJR143C
initial amount: NaN
is: sce01030
is: S000003904
is: P46971

metaid M 1109
is: CHEBI:16199
name: urea
constant: false
is: SBO:0000299
in compartment: metaid C 4
type: Species
has only substance units: false
initial amount: NaN
boundary condition: true
initial concentration: NaN

080149
units: 958314
value: 0.0
type: LocalParameter

078296
units: 958314
value: 0.0
type: LocalParameter

111577
stoichiometry: 1.0
species: metaid M 300
type: SpeciesReference

095937
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

978059
stoichiometry: 1.0
species: metaid M 324
type: SpeciesReference

metaid R CEM1 3
kinetic law: 978516
product: 978492
reactant: 978444
reactant: 978456
product: 978480
product: 978468
is: http://identifiers.org/ec-code/2.3.1.41
modifier: 978504
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog
reversible: false
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
is: SBO:0000176
type: Reaction
fast: false

133538
units: 958314
value: 0.0
type: LocalParameter

105006
units: 958314
value: 0.0
type: LocalParameter

034007
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

019402
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

115030
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

064843
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

121391
stoichiometry: 1.0
species: metaid M 993
type: SpeciesReference

034152
stoichiometry: 1.0
species: metaid M 40
type: SpeciesReference

076692
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R U114
kinetic law: 085778
product: 085766
reactant: 085754
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Transport of tetrahydrofolate, mitochondrial
type: Reaction

127768
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

969983
units: 958314
value: 0.09314409000001
type: LocalParameter

040246
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R CEM1 6
kinetic law: 978913
is: http://identifiers.org/ec-code/2.3.1.41
reactant: 978853
reversible: false
fast: false
modifier: 978901
is: SBO:0000176
type: Reaction
product: 978865
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog
product: 978877
reactant: 978841
product: 978889

032516
stoichiometry: 1.0
species: metaid M 795
type: SpeciesReference

117487
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

047074
stoichiometry: 1.0
species: metaid M 952
type: SpeciesReference

035108
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R FOL2
kinetic law: 006835
is: SBO:0000176
is: http://identifiers.org/ec-code/3.5.4.16
reactant: 006787
type: Reaction
notes: SUBSYSTEM: Folate metabolism
modifier: 006823
reversible: false
product: 006799
fast: false
name: GTP cyclohydrolase 1
product: 006811

086417
units: 958314
value: 0.0
type: LocalParameter

071067
stoichiometry: 1.0
species: metaid M 845
type: SpeciesReference

063324
stoichiometry: 1.0
species: metaid M 503
type: SpeciesReference

metaid R HXT10 1
is: SBO:0000185
type: Reaction
product: 025748
modifier: 025760
name: Hexose transporter HXT10
reversible: false
fast: false
kinetic law: 025772
reactant: 025736
notes: SUBSYSTEM: Transport, extracellular

110888
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R CEM1 5
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
product: 978757
is: http://identifiers.org/ec-code/2.3.1.41
reactant: 978721
modifier: 978769
reversible: false
fast: false
kinetic law: 978781
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog
product: 978733
reactant: 978709
product: 978745
is: SBO:0000176
type: Reaction

964211
units: 958314
value: 0.0
type: LocalParameter

049075
stoichiometry: 1.0
species: metaid M 113
type: SpeciesReference

089692
units: 958314
value: 0.0
type: LocalParameter

105091
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

079221
units: 958314
value: 0.0
type: LocalParameter

004688
stoichiometry: 1.0
species: metaid M 491
type: SpeciesReference

metaid R FOL3
fast: false
is: http://identifiers.org/ec-code/6.3.2.17
name: Folylpolyglutamate synthase
notes: SUBSYSTEM: Folate metabolism
type: Reaction
is: SBO:0000176
reversible: true
product: 006932
reactant: 006896
reactant: 006908
modifier: 006968
product: 006956
reactant: 006920
product: 006944
kinetic law: 006980

961460
stoichiometry: 1.0
species: metaid M 175
type: SpeciesReference

061891
stoichiometry: 2.0
species: metaid M 214
type: SpeciesReference

100610
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

007209
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

128117
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R HXT10 2
notes: SUBSYSTEM: Transport, extracellular
reversible: false
product: 025844
type: Reaction
name: Hexose transporter HXT10
modifier: 025856
reactant: 025832
kinetic law: 025868
fast: false
is: SBO:0000185

068449
stoichiometry: 1.0
species: metaid M 495
type: SpeciesReference

986671
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

044060
stoichiometry: 1.0
species: metaid M 657
type: SpeciesReference

metaid R CEM1 8
is: http://identifiers.org/ec-code/2.3.1.41
product: 979129
kinetic law: 979177
product: 979141
reactant: 979117
is: SBO:0000176
type: Reaction
product: 979153
fast: false
reactant: 979105
reversible: false
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
modifier: 979165
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog

metaid R CRC1
name: Mitochondrial carnitine carrier
reversible: false
reactant: 981754
fast: false
product: 981766
is: SBO:0000185
modifier: 981790
product: 981778
notes: SUBSYSTEM: Transport, mitochondrial
kinetic law: 981802
type: Reaction
reactant: 981742

029183
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

994740
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

982080
units: 958314
value: 1.287E-5
type: LocalParameter

011306
units: 958314
value: 0.0
type: LocalParameter

081646
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

006425
units: 958314
value: 0.0
type: LocalParameter

049967
stoichiometry: 1.0
species: metaid M 241
type: SpeciesReference

970574
stoichiometry: 1.0
species: metaid M 575
type: SpeciesReference

021822
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

982637
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R ATH1
name: Vacuolar acid trehalase
product: 971794
kinetic law: 971818
fast: false
reversible: false
modifier: 971806
notes: SUBSYSTEM: Trehalose metabolism
is: SBO:0000176
is: http://identifiers.org/ec-code/3.2.1.28
reactant: 971782
type: Reaction

metaid R HXT10 3
kinetic law: 025964
fast: false
type: Reaction
reversible: false
reactant: 025928
modifier: 025952
name: Hexose transporter HXT10
notes: SUBSYSTEM: Transport, extracellular
product: 025940
is: SBO:0000185

139851
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R CEM1 7
reactant: 978973
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
kinetic law: 979045
fast: false
product: 979009
reversible: false
reactant: 978985
product: 979021
name: 3-oxoacyl-[acyl-carrier-protein] synthase homolog
product: 978997
modifier: 979033
is: SBO:0000176
type: Reaction
is: http://identifiers.org/ec-code/2.3.1.41

989915
units: 958314
value: 0.04086069000001
type: LocalParameter

103596
stoichiometry: 1.0
species: metaid M 57
type: SpeciesReference

082709
stoichiometry: 1.0
species: metaid M 693
type: SpeciesReference

134056
stoichiometry: 1.0
species: metaid M 293
type: SpeciesReference

007803
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

143563
stoichiometry: 0.25728
species: metaid M 627
type: SpeciesReference

110083
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R HXT10 4
notes: SUBSYSTEM: Transport, extracellular
type: Reaction
reversible: false
reactant: 026024
name: Hexose transporter HXT10
kinetic law: 026060
product: 026036
is: SBO:0000185
modifier: 026048
fast: false

991790
stoichiometry: 1.0
species: metaid M 975
type: SpeciesReference

129071
stoichiometry: 1.0
species: metaid M 1084
type: SpeciesReference

000772
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

086862
stoichiometry: 1.0
species: metaid M 502
type: SpeciesReference

967035
stoichiometry: 1.0
species: metaid M 253
type: SpeciesReference

978997
stoichiometry: 1.0
species: metaid M 138
type: SpeciesReference

959967
stoichiometry: 1.0
species: metaid M 690
type: SpeciesReference

139707
units: 958314
value: 0.0
type: LocalParameter

metaid R PSD1
notes: SUBSYSTEM: Phospholipid biosynthesis
product: 065000
modifier: 065024
is: SBO:0000176
reactant: 064987
reversible: false
type: Reaction
name: Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
product: 065012
kinetic law: 065036
is: http://identifiers.org/ec-code/4.1.1.65
fast: false

metaid E 511
has only substance units: false
constant: false
initial amount: NaN
is: Q04958
is: S000004524
boundary condition: false
in compartment: metaid C 2
notes: SHORT NAME: NTE1
name: YML059C
is: SBO:0000014
initial concentration: NaN
type: Species

metaid R ARO9 1
type: Reaction
notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
modifier: 970732
reactant: 970684
is: http://identifiers.org/ec-code/2.6.1.-
fast: false
product: 970720
product: 970708
is: SBO:0000176
name: Aromatic amino acid aminotransferase 2
kinetic law: 970744
reversible: true
reactant: 970696

065216
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

105707
units: 958314
value: -1.5863262909E-4
type: LocalParameter

118319
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

083770
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

061265
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

007004
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

118969
stoichiometry: 1.0
species: metaid M 371
type: SpeciesReference

962331
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

039813
units: 958314
value: 0.08172138000001
type: LocalParameter

139007
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 510
initial concentration: NaN
constant: false
name: YML056C
in compartment: metaid C 2
is: P50094
initial amount: NaN
notes: SHORT NAME: IMD4
boundary condition: false
is: S000004520
is: SBO:0000014
type: Species
has only substance units: false
is: sce00230

017811
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R ARO9 2
notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
fast: false
reversible: false
reactant: 970806
reactant: 970818
type: Reaction
product: 970843
name: Aromatic amino acid aminotransferase 2
is: SBO:0000176
modifier: 970855
kinetic law: 970867
product: 970830
is: http://identifiers.org/ec-code/2.6.1.-

120127
stoichiometry: 1.0
species: metaid M 689
type: SpeciesReference

044529
units: 958314
value: 0.01951053
type: LocalParameter

000135
stoichiometry: 1.0
species: metaid M 721
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111794
stoichiometry: 1.0
species: metaid M 693
type: SpeciesReference

102427
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

112312
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

119645
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

141453
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

142479
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

086237
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

048349
units: 958314
value: 0.0
type: LocalParameter

metaid R CHOxtI
kinetic law: 123274
product: 123262
reactant: 123250
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of choline
type: Reaction

050738
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

046941
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

metaid E 513
is: sce00100
initial amount: NaN
boundary condition: false
notes: SHORT NAME: HMG1
is: SBO:0000014
type: Species
name: YML075C
is: P12683
in compartment: metaid C 2
constant: false
is: S000004540
has only substance units: false
initial concentration: NaN

107960
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R U186
product: 092349
is: SBO:0000185
fast: false
name: Transport of cytidine, extracellular
reversible: false
notes: SUBSYSTEM: Transport, extracellular
reactant: 092325
type: Reaction
reactant: 092337
kinetic law: 092361

998822
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

972677
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

043408
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

072599
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

090978
stoichiometry: 1.0
species: metaid M 709
type: SpeciesReference

070910
units: 958314
value: 0.0
type: LocalParameter

106598
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

085068
stoichiometry: 1.0
species: metaid M 702
type: SpeciesReference

096443
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

142189
stoichiometry: 1.0
species: metaid M 1108
type: SpeciesReference

987152
stoichiometry: 1.0
species: metaid M 411
type: SpeciesReference

103056
stoichiometry: 1.0
species: metaid M 791
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109699
stoichiometry: 1.0
species: metaid M 691
type: SpeciesReference

034224
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

974059
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 512
initial concentration: NaN
has only substance units: false
initial amount: NaN
in compartment: metaid C 2
is: S000004535
is: SBO:0000014
boundary condition: false
notes: SHORT NAME: DAK1
is: P54838
type: Species
name: YML070W
is: sce00561
constant: false

metaid R PSD2
name: Phosphatidylserine decarboxylase proenzyme 2
type: Reaction
product: 065120
fast: false
reversible: false
reactant: 065096
product: 065108
is: SBO:0000176
notes: SUBSYSTEM: Phospholipid biosynthesis
kinetic law: 065144
modifier: 065132
is: http://identifiers.org/ec-code/4.1.1.65

001927
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

978276
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

986214
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

101874
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

010802
stoichiometry: 1.0
species: metaid M 963
type: SpeciesReference

087367
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

007427
units: 958314
value: 0.0
type: LocalParameter

093075
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

970357
stoichiometry: 1.0
species: metaid M 768
type: SpeciesReference

006763
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

132464
stoichiometry: 1.0
species: metaid M 993
type: SpeciesReference

035325
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 515
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type: Species
is: SBO:0000014
initial concentration: NaN
boundary condition: false
constant: false
is: S000004566
in compartment: metaid C 2
is: P38427
name: YML100W
initial amount: NaN
notes: SHORT NAME: TSL1

094108
units: 958314
value: 0.0
type: LocalParameter

054107
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

056650
stoichiometry: 1.0
species: metaid M 774
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015036
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

076125
units: 958314
value: 1.287E-5
type: LocalParameter

055286
stoichiometry: 1.0
species: metaid M 267
type: SpeciesReference

metaid R THR1
is: SBO:0000176
fast: false
modifier: 079872
type: Reaction
kinetic law: 079884
is: http://identifiers.org/ec-code/2.7.1.39
reversible: false
product: 079847
product: 079860
reactant: 079823
reactant: 079835
notes: SUBSYSTEM: Glycine, serine, and threonine metabolism
name: Homoserine kinase

107368
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

086562
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

027539
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

072141
stoichiometry: 1.0
species: metaid M 689
type: SpeciesReference

986454
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

020812
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

141888
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

965300
units: 958314
value: 0.0
type: LocalParameter

080583
stoichiometry: 1.0
species: metaid M 839
type: SpeciesReference

036252
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 514
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is: sce00920
is: S000004547
in compartment: metaid C 2
is: Q04533
initial concentration: NaN
constant: false
boundary condition: false
is: sce00450
has only substance units: false
name: YML082W
initial amount: NaN
is: sce00271
type: Species
is: SBO:0000014

005521
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

017928
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

134778
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

120996
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

143345
stoichiometry: 0.35734
species: metaid M 554
type: SpeciesReference

metaid R O2xtO
kinetic law: 139658
product: 139646
reactant: 139634
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of oxygen
type: Reaction

979946
stoichiometry: 1.0
species: metaid M 962
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143406
stoichiometry: 0.268
species: metaid M 575
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142261
stoichiometry: 1.0
species: metaid M 971
type: SpeciesReference

052506
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

069496
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

138320
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

050209
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species: metaid M 801
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metaid E 517
boundary condition: false
is: sce00130
is: P49017
initial concentration: NaN
notes: SHORT NAME: COQ5
is: SBO:0000014
type: Species
is: S000004578
in compartment: metaid C 2
has only substance units: false
constant: false
initial amount: NaN
name: YML110C

986346
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

126183
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

013493
stoichiometry: 1.0
species: metaid M 689
type: SpeciesReference

081865
units: 958314
value: 0.01092
type: LocalParameter

017222
units: 958314
value: 0.0
type: LocalParameter

100034
stoichiometry: 1.0
species: metaid M 573
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112825
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species: metaid M 356
type: SpeciesReference

016413
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

049749
units: 958314
value: 0.0
type: LocalParameter

064409
stoichiometry: 1.0
species: metaid M 191
type: SpeciesReference

140104
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

068666
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

983878
stoichiometry: 1.0
species: metaid M 264
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000436
units: 958314
value: 0.0
type: LocalParameter

990554
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

095600
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

969052
units: 958314
value: 0.05295810000001
type: LocalParameter

metaid R U171
product: 090798
name: Transport of putrescine, extracellular
reversible: false
is: SBO:0000185
fast: false
reactant: 090774
type: Reaction
notes: SUBSYSTEM: Transport, extracellular
reactant: 090786
kinetic law: 090810

metaid E 516
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notes: SHORT NAME: URA5
is: P13298
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in compartment: metaid C 2
initial concentration: NaN
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is: S000004574
boundary condition: false
initial amount: NaN
is: SBO:0000014
has only substance units: false
type: Species

983251
stoichiometry: 1.0
species: metaid M 479
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122321
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species: metaid M 1004
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973301
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

005074
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

973975
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value: 0.0
type: LocalParameter

089536
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species: metaid M 334
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057601
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

054216
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

993368
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

136800
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

043155
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R CHOxtO
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product: 134320
reactant: 134308
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of choline
type: Reaction

metaid E 624
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042473
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

020702
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

971083
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species: metaid M 262
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090654
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value: 1000.0
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983674
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species: metaid M 318
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139428
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value: 1000.0
name: UPPER_BOUND
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species: metaid M 727
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099203
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species: metaid M 267
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097962
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species: metaid M 733
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metaid R O2xtI
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product: 128574
reactant: 128562
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of oxygen
type: Reaction

056542
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species: metaid M 56
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117596
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

016305
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value: 0.0
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type: LocalParameter

024138
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value: 0.08801663029614
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994006
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species: metaid M 768
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050317
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species: metaid M 692
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137188
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species: metaid M 476
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metaid E 623
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initial amount: NaN
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constant: false
is: sce00030
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notes: SHORT NAME: RKI1
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968417
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value: 0.0
type: LocalParameter

006871
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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087475
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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977614
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species: metaid M 413
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metaid R U94
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product: 104512
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fast: false
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type: Reaction
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product: 104524

037035
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species: metaid M 795
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metaid R U129
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notes: SUBSYSTEM: Transport, mitochondrial
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name: Transport of 2-oxoadipate, mitochondrial
type: Reaction

970201
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value: 0.0
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093183
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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value: 1000.0
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species: metaid M 712
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994319
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value: 0.0
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000544
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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species: metaid M 802
type: SpeciesReference

983987
stoichiometry: 1.0
species: metaid M 488
type: SpeciesReference

106261
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid M 1111
in compartment: metaid C 4
constant: false
is: CHEBI:16414
is: SBO:0000299
type: Species
has only substance units: false
initial amount: NaN
initial concentration: NaN
boundary condition: true
name: L-valine

111010
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 620
is: SBO:0000014
notes: SHORT NAME: NRT1
constant: false
boundary condition: false
in compartment: metaid C 2
initial concentration: NaN
is: S000005597
name: YOR071C
type: Species
has only substance units: false
initial amount: NaN
is: Q08485

044637
units: 958314
value: 0.03623373000001
type: LocalParameter

metaid R MET17 1
name: O-acetylhomoserine sulfhydrylase
fast: false
type: Reaction
reactant: 044073
product: 044097
kinetic law: 044121
product: 044085
is: SBO:0000176
reversible: false
is: http://identifiers.org/ec-code/2.5.1.49
modifier: 044109
notes: SUBSYSTEM: Methionine metabolism
reactant: 044060

080041
units: 958314
value: 0.0
type: LocalParameter

106104
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

133984
stoichiometry: 1.0
species: metaid M 1011
type: SpeciesReference

035745
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

020509
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 1112
has only substance units: false
boundary condition: true
constant: false
name: pyridoxine
in compartment: metaid C 4
is: SBO:0000299
initial concentration: NaN
type: Species
is: CHEBI:16709
initial amount: NaN

metaid E 409
initial amount: NaN
boundary condition: false
type: Species
name: YKL024C
notes: SHORT NAME: URA6
in compartment: metaid C 2
has only substance units: false
is: sce00240
is: P15700
constant: false
is: SBO:0000014
is: S000001507
initial concentration: NaN

046881
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

133839
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

058058
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

081757
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

979201
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

962440
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

039922
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

086127
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

020221
stoichiometry: 1.0
species: metaid M 323
type: SpeciesReference

000664
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

105816
stoichiometry: 1.0
species: metaid M 721
type: SpeciesReference

091927
units: 958314
value: 0.0
type: LocalParameter

126940
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

040138
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

015508
stoichiometry: 1.0
species: metaid M 13
type: SpeciesReference

111686
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

036360
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

101982
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 622
is: S000005607
constant: false
boundary condition: false
in compartment: metaid C 2
initial concentration: NaN
type: Species
initial amount: NaN
name: YOR081C
notes: SHORT NAME: TGL5
has only substance units: false
is: Q12043
is: SBO:0000014

metaid R GLYxtO
kinetic law: 137296
product: 137284
reactant: 137272
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of glycine
type: Reaction

985925
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

080257
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R MET17 3
product: 044337
is: http://identifiers.org/ec-code/2.5.1.47
reactant: 044301
reversible: false
is: SBO:0000176
kinetic law: 044361
fast: false
modifier: 044349
reactant: 044313
name: O-acetylserine sulfhydrylase
product: 044325
type: Reaction
notes: SUBSYSTEM: Methionine metabolism

073104
stoichiometry: 1.0
species: metaid M 220
type: SpeciesReference

118427
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

968343
stoichiometry: 1.0
species: metaid M 689
type: SpeciesReference

001818
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid M 1110
is: CHEBI:16704
name: uridine
boundary condition: true
initial amount: NaN
in compartment: metaid C 4
constant: false
initial concentration: NaN
is: SBO:0000299
type: Species
has only substance units: false

969270
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

094349
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

978564
units: 958314
value: 0.0881236135997
type: LocalParameter

087948
stoichiometry: 1.0
species: metaid M 389
type: SpeciesReference

057106
stoichiometry: 1.0
species: metaid M 666
type: SpeciesReference

079739
stoichiometry: 1.0
species: metaid M 879
type: SpeciesReference

metaid E 621
boundary condition: false
initial concentration: NaN
has only substance units: false
name: YOR074C
is: SBO:0000014
constant: false
in compartment: metaid C 2
is: sce00670
notes: SHORT NAME: CDC21
is: P06785
type: Species
is: S000005600
initial amount: NaN
is: sce00240

metaid R U72
fast: false
name: ThiG protein
reversible: false
is: SBO:0000176
reactant: 101922
notes: SUBSYSTEM: Thiamine (vitamin B1) metabolism
kinetic law: 101970
product: 101946
type: Reaction
reactant: 101898
product: 101958
product: 101934
reactant: 101910

141345
stoichiometry: 1.0
species: metaid M 1098
type: SpeciesReference

metaid R MET17 2
product: 044217
is: SBO:0000176
product: 044205
fast: false
name: O-acetylserine sulfhydrylase
reactant: 044181
is: http://identifiers.org/ec-code/2.5.1.47
kinetic law: 044241
modifier: 044229
type: Reaction
reversible: false
reactant: 044193
notes: SUBSYSTEM: Methionine metabolism

072442
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

970429
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

959736
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

020437
units: 958314
value: 0.0
type: LocalParameter

metaid R DED81
fast: false
modifier: 984769
reactant: 984697
is: http://identifiers.org/ec-code/6.1.1.22
notes: SUBSYSTEM: tRNA synthesis
name: Asparaginyl-tRNA synthetase, cytoplasmic
reactant: 984709
reactant: 984721
type: Reaction
product: 984733
kinetic law: 984781
product: 984757
is: SBO:0000176
reversible: false
product: 984745

143599
stoichiometry: 0.02
species: metaid M 864
type: SpeciesReference

026204
units: 958314
value: 0.0
type: LocalParameter

998882
stoichiometry: 1.0
species: metaid M 218
type: SpeciesReference

143068
stoichiometry: 0.002884
species: metaid M 761
type: SpeciesReference

128913
stoichiometry: 1.0
species: metaid M 751
type: SpeciesReference

metaid R HXT11 5
notes: SUBSYSTEM: Transport, extracellular
is: SBO:0000185
product: 026517
reversible: false
reactant: 026505
type: Reaction
kinetic law: 026542
fast: false
modifier: 026530
name: Hexose transporter HXT11

metaid R YPC1 1
notes: SUBSYSTEM: Sphingoglycolipid metabolism
product: 119911
name: Alkaline ceramidase YPC1
reactant: 119899
is: http://identifiers.org/ec-code/3.5.1.-
is: SBO:0000176
kinetic law: 119935
fast: false
reversible: false
modifier: 119923
type: Reaction

metaid R SPRMxtO
kinetic law: 141441
product: 141429
reactant: 141417
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of spermine
type: Reaction

086513
stoichiometry: 1.0
species: metaid M 712
type: SpeciesReference

064638
stoichiometry: 1.0
species: metaid M 356
type: SpeciesReference

013578
units: 958314
value: 0.0
type: LocalParameter

103560
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

990626
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

091339
units: 958314
value: 0.0
type: LocalParameter

133009
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

973722
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

962586
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R YJL068C
product: 116787
reversible: true
reactant: 116775
modifier: 116812
is: SBO:0000176
type: Reaction
fast: false
is: http://identifiers.org/ec-code/3.1.2.12
name: S-formylglutathione hydrolase
kinetic law: 116824
notes: SUBSYSTEM: Pyruvate metabolism
product: 116799

138428
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

144143
stoichiometry: 0.098
species: metaid M 557
type: SpeciesReference

081079
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R HXT11 4
reversible: false
reactant: 026409
type: Reaction
kinetic law: 026445
modifier: 026433
fast: false
name: Hexose transporter HXT11
notes: SUBSYSTEM: Transport, extracellular
is: SBO:0000185
product: 026421

082323
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

972083
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

053409
stoichiometry: 1.0
species: metaid M 253
type: SpeciesReference

metaid R OLE1 c14
is: SBO:0000176
modifier: 051412
reversible: false
kinetic law: 051424
name: Acyl-CoA desaturase 1
product: 051400
is: http://identifiers.org/ec-code/1.14.19.1
fast: false
notes: SUBSYSTEM: Fatty acid biosynthesis
type: Reaction
reactant: 051388
reactant: 051376

970586
stoichiometry: 1.0
species: metaid M 83
type: SpeciesReference

049979
stoichiometry: 2.0
species: metaid M 245
type: SpeciesReference

090918
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

120767
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

055058
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

006413
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

010850
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

101814
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

081634
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

093795
stoichiometry: 1.0
species: metaid M 448
type: SpeciesReference

122575
stoichiometry: 1.0
species: metaid M 1007
type: SpeciesReference

099263
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

069244
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid E 30
notes: SHORT NAME: GAL1
has only substance units: false
is: sce00052
is: S000000224
name: YBR020W
boundary condition: false
constant: false
type: Species
is: P04385
is: SBO:0000014
initial concentration: NaN
initial amount: NaN
in compartment: metaid C 2

metaid R HXT11 3
kinetic law: 026348
reactant: 026312
modifier: 026336
fast: false
name: Hexose transporter HXT11
product: 026324
is: SBO:0000185
type: Reaction
reversible: false
notes: SUBSYSTEM: Transport, extracellular

095853
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

128129
units: 958314
value: 0.0
type: LocalParameter

metaid R U86
reversible: true
reactant: 103487
is: SBO:0000176
name: 8-amino-7-oxononanoate synthase
type: Reaction
notes: SUBSYSTEM: Pantothenate and CoA metabolism
reactant: 103474
product: 103511
kinetic law: 103535
is: http://identifiers.org/ec-code/2.3.1.47
product: 103523
fast: false
product: 103499

metaid R U117
kinetic law: 086031
product: 086019
reactant: 086007
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Transport of glycine, mitochondrial
type: Reaction

043769
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

983553
stoichiometry: 1.0
species: metaid M 239
type: SpeciesReference

139549
stoichiometry: 1.0
species: metaid M 709
type: SpeciesReference

037155
stoichiometry: 2.0
species: metaid M 461
type: SpeciesReference

057722
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

064300
stoichiometry: 1.0
species: metaid M 253
type: SpeciesReference

035915
stoichiometry: 1.0
species: metaid M 534
type: SpeciesReference

136259
stoichiometry: 1.0
species: metaid M 452
type: SpeciesReference

043034
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

136884
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

968465
stoichiometry: 1.0
species: metaid M 693
type: SpeciesReference

968150
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

099323
stoichiometry: 1.0
species: metaid M 483
type: SpeciesReference

metaid R HXT11 2
modifier: 026240
reactant: 026216
kinetic law: 026252
name: Hexose transporter HXT11
product: 026228
type: Reaction
notes: SUBSYSTEM: Transport, extracellular
fast: false
reversible: false
is: SBO:0000185

metaid E 31
constant: false
type: Species
is: SBO:0000014
initial amount: NaN
is: P05316
boundary condition: false
in compartment: metaid C 2
is: S000000225
name: YBR021W
has only substance units: false
initial concentration: NaN
notes: SHORT NAME: FUR4

035673
stoichiometry: 1.0
species: metaid M 394
type: SpeciesReference

014097
stoichiometry: 1.0
species: metaid M 693
type: SpeciesReference

metaid M 409
name: dolichol
type: Species
in compartment: metaid C 2
is: SBO:0000299
constant: false
has only substance units: false
is: CHEBI:16091
initial concentration: NaN
initial amount: NaN
boundary condition: false

metaid R OLE1 c16
reactant: 051484
is: http://identifiers.org/ec-code/1.14.19.1
modifier: 051520
reversible: false
reactant: 051496
type: Reaction
name: Acyl-CoA desaturase 1
fast: false
notes: SUBSYSTEM: Fatty acid biosynthesis
is: SBO:0000176
kinetic law: 051532
product: 051508

086405
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

037095
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

047086
stoichiometry: 1.0
species: metaid M 254
type: SpeciesReference

076089
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

050438
stoichiometry: 1.0
species: metaid M 692
type: SpeciesReference

963859
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

961980
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

028045
stoichiometry: 1.0
species: metaid M 651
type: SpeciesReference

974433
stoichiometry: 1.0
species: metaid M 756
type: SpeciesReference

032891
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

072491
stoichiometry: 1.0
species: metaid M 447
type: SpeciesReference

984384
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

142225
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R ILV3 3
is: SBO:0000176
reactant: 033141
modifier: 033165
type: Reaction
kinetic law: 033177
name: Dihydroxy-acid dehydratase, mitochondrial
is: http://identifiers.org/ec-code/4.2.1.9
reversible: false
notes: SUBSYSTEM: Branched chain amino acid metabolism (valine, leucine, and isoleucine)
fast: false
product: 033153

086007
stoichiometry: 1.0
species: metaid M 484
type: SpeciesReference

977734
stoichiometry: 1.0
species: metaid M 698
type: SpeciesReference

metaid R HXT4 2
product: 028545
reversible: false
modifier: 028557
notes: SUBSYSTEM: Transport, extracellular
name: Low-affinity glucose transporter HXT4
reactant: 028533
fast: false
is: SBO:0000185
type: Reaction
kinetic law: 028569

112360
stoichiometry: 1.0
species: metaid M 36
type: SpeciesReference

999665
stoichiometry: 1.0
species: metaid M 919
type: SpeciesReference

000051
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

064855
units: 958314
value: 0.03261336000002
type: LocalParameter

001842
stoichiometry: 1.0
species: metaid M 406
type: SpeciesReference

111541
stoichiometry: 1.0
species: metaid M 322
type: SpeciesReference

012691
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R GFA1
name: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]
fast: false
kinetic law: 014278
product: 014253
reactant: 014217
reactant: 014229
product: 014241
type: Reaction
is: http://identifiers.org/ec-code/2.6.1.16
modifier: 014265
is: SBO:0000176
notes: SUBSYSTEM: Glutamate metabolism (aminosugars metabolism)
reversible: false

metaid R ILV3 2
reactant: 033045
reversible: false
notes: SUBSYSTEM: Branched chain amino acid metabolism (valine, leucine, and isoleucine)
type: Reaction
fast: false
name: Dihydroxy-acid dehydratase, mitochondrial
kinetic law: 033081
product: 033057
is: SBO:0000176
is: http://identifiers.org/ec-code/4.2.1.9
modifier: 033069

080113
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R HXT4 3
name: Low-affinity glucose transporter HXT4
kinetic law: 028666
is: SBO:0000185
notes: SUBSYSTEM: Transport, extracellular
fast: false
reversible: false
modifier: 028654
reactant: 028630
type: Reaction
product: 028642

109445
stoichiometry: 1.0
species: metaid M 316
type: SpeciesReference

metaid R OLE1 c18
reactant: 051592
product: 051616
kinetic law: 051640
type: Reaction
name: Acyl-CoA desaturase 1
is: http://identifiers.org/ec-code/1.14.19.1
modifier: 051628
reactant: 051604
reversible: false
fast: false
notes: SUBSYSTEM: Fatty acid biosynthesis
is: SBO:0000176

118547
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

005014
stoichiometry: 1.0
species: metaid M 491
type: SpeciesReference

073176
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

959772
stoichiometry: 1.0
species: metaid M 205
type: SpeciesReference

015628
stoichiometry: 2.0
species: metaid M 473
type: SpeciesReference

metaid R UGA4 1
is: SBO:0000185
kinetic law: 106983
name: GABA-specific permease
reactant: 106935
product: 106959
reactant: 106947
modifier: 106971
reversible: false
type: Reaction
notes: SUBSYSTEM: Transport, extracellular
fast: false

965576
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

123406
units: 958314
value: 0.0
type: LocalParameter

974829
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

016970
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

052023
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

141030
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

995693
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R ILV3 1
notes: SUBSYSTEM: Branched chain amino acid metabolism (valine, leucine, and isoleucine)
product: 032954
is: SBO:0000176
fast: false
kinetic law: 032980
modifier: 032967
name: Dihydroxy-acid dehydratase, mitochondrial
reactant: 032942
is: http://identifiers.org/ec-code/4.2.1.9
type: Reaction
reversible: false

metaid M 559
is: CHEBI:17196
is: SBO:0000299
in compartment: metaid C 2
has only substance units: false
initial amount: NaN
boundary condition: false
constant: false
type: Species
name: L-asparagine
initial concentration: NaN

053638
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

133370
units: 958314
value: 0.0
type: LocalParameter

046131
stoichiometry: 1.0
species: metaid M 796
type: SpeciesReference

061012
stoichiometry: 1.0
species: metaid M 119
type: SpeciesReference

036588
units: 958314
value: 0.0
type: LocalParameter

021209
units: 958314
value: 0.02926599
type: LocalParameter

016257
stoichiometry: 1.0
species: metaid M 357
type: SpeciesReference

metaid R CKI1
reactant: 980514
modifier: 980562
product: 980550
fast: false
reversible: false
reactant: 980526
name: Choline kinase
kinetic law: 980574
is: SBO:0000176
notes: SUBSYSTEM: Phospholipid biosynthesis
type: Reaction
product: 980538
is: http://identifiers.org/ec-code/2.7.1.32

metaid R ISC1 3 2
type: Reaction
notes: SUBSYSTEM: Sphingoglycolipid metabolism
reversible: false
reactant: 036023
fast: false
product: 036047
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name: Inositol phosphosphingolipids phospholipase C
is: SBO:0000176
kinetic law: 036071
modifier: 036059
product: 036035

057228
stoichiometry: 1.0
species: metaid M 217
type: SpeciesReference

007350
stoichiometry: 1.0
species: metaid M 108
type: SpeciesReference

metaid R HXT4 1
kinetic law: 028473
fast: false
is: SBO:0000185
modifier: 028461
notes: SUBSYSTEM: Transport, extracellular
reversible: false
product: 028448
name: Low-affinity glucose transporter HXT4
reactant: 028436
type: Reaction

105888
stoichiometry: 1.0
species: metaid M 280
type: SpeciesReference

963213
stoichiometry: 1.0
species: metaid M 495
type: SpeciesReference

099902
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value: 0.09337380000001
type: LocalParameter

123719
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid M 558
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is: SBO:0000299
has only substance units: false
name: L-arginyl-tRNA(Arg)
notes: FORMULA: C21H33N9O11PR(C5H8O6PR)n
initial amount: NaN
is: CHEBI:18366
constant: false
type: Species
boundary condition: false
initial concentration: NaN

085296
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R YPC1 2
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type: Reaction
name: Alkaline ceramidase YPC1
modifier: 120019
is: SBO:0000176
notes: SUBSYSTEM: Sphingoglycolipid metabolism
reactant: 119995
kinetic law: 120031
reversible: false
is: http://identifiers.org/ec-code/3.5.1.-
fast: false

090702
stoichiometry: 1.0
species: metaid M 361
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086934
units: 958314
value: 0.0
type: LocalParameter

078851
units: 958314
value: 0.0
type: LocalParameter

115259
stoichiometry: 1.0
species: metaid M 497
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106141
stoichiometry: 1.0
species: metaid M 296
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985312
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

077779
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

033598
stoichiometry: 1.0
species: metaid M 526
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119185
stoichiometry: 1.0
species: metaid M 364
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046821
stoichiometry: 1.0
species: metaid M 253
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039970
stoichiometry: 1.0
species: metaid M 757
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metaid R ISC1 3 1
product: 035927
is: http://identifiers.org/ec-code/3.1.4.-
name: Inositol phosphosphingolipids phospholipase C
kinetic law: 035963
type: Reaction
notes: SUBSYSTEM: Sphingoglycolipid metabolism
reactant: 035915
modifier: 035951
product: 035939
is: SBO:0000176
reversible: false
fast: false

057950
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

048072
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

121294
units: 958314
value: 0.0
type: LocalParameter

070291
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

124092
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species: metaid M 1025
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043456
stoichiometry: 1.0
species: metaid M 866
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959662
stoichiometry: 1.0
species: metaid M 644
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129875
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value: 0.0
name: UPPER_BOUND
type: LocalParameter

019329
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

001999
stoichiometry: 1.0
species: metaid M 691
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085188
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

968573
stoichiometry: 1.0
species: metaid M 321
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962065
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value: 0.04229004000001
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090858
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value: 0.0
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107912
stoichiometry: 1.0
species: metaid M 26
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121080
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid M 404
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is: C00107
initial concentration: NaN
boundary condition: false
notes: FORMULA: C4H6N2O3R2
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initial amount: NaN
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is: SBO:0000299
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987032
units: 958314
value: 0.0
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142334
units: 958314
value: 0.0
type: LocalParameter

034104
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

128792
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 249
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is: sce00230
in compartment: metaid C 2
initial amount: NaN
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is: S000003217
boundary condition: false
is: SBO:0000014
constant: false
notes: SHORT NAME: PDE1
type: Species
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137344
units: 958314
value: 0.0
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016861
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

055599
stoichiometry: 1.0
species: metaid M 267
type: SpeciesReference

047698
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

054902
units: 958314
value: 0.0
type: LocalParameter

978131
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

043528
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

015737
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species: metaid M 578
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057336
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species: metaid M 217
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004156
stoichiometry: 1.0
species: metaid M 501
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117910
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species: metaid M 796
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101753
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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106538
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

073285
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

094481
stoichiometry: 1.0
species: metaid M 861
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metaid M 403
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initial concentration: NaN
boundary condition: false
has only substance units: false
in compartment: metaid C 2
name: dipeptide
notes: FORMULA: C4H6N2O3R2
type: Species
initial amount: NaN
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is: SBO:0000299

991153
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

141575
units: 958314
value: 0.0
type: LocalParameter

095480
stoichiometry: 1.0
species: metaid M 230
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977842
stoichiometry: 1.0
species: metaid M 385
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109554
stoichiometry: 1.0
species: metaid M 972
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126255
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

119077
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

003336
stoichiometry: 1.0
species: metaid M 291
type: SpeciesReference

071511
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid M 402
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boundary condition: false
type: Species
is: CHEBI:28997
in compartment: metaid C 3
has only substance units: false
initial amount: NaN
constant: false
name: deoxyinosine
is: SBO:0000299

metaid R UGA4 2
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is: SBO:0000185
reversible: false
reactant: 107055
modifier: 107079
name: GABA-specific permease
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reactant: 107043
notes: SUBSYSTEM: Transport, extracellular
type: Reaction
product: 107067

989371
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

985608
stoichiometry: 1.0
species: metaid M 639
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metaid E 248
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type: Species
boundary condition: false
is: sce00970
is: S000003214
initial concentration: NaN
initial amount: NaN
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has only substance units: false
is: sce00251
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is: SBO:0000014
notes: SHORT NAME: GUS1
constant: false

965684
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R CO2xtI
kinetic law: 123442
product: 123430
reactant: 123418
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of CO2
type: Reaction

057661
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

130056
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

140982
units: 958314
value: 0.0
type: LocalParameter

016100
stoichiometry: 1.0
species: metaid M 691
type: SpeciesReference

982733
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

963105
stoichiometry: 1.0
species: metaid M 262
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050666
stoichiometry: 1.0
species: metaid M 694
type: SpeciesReference

959349
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

967095
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid M 401
name: dimethylallyl diphosphate
type: Species
in compartment: metaid C 2
is: CHEBI:16057
initial concentration: NaN
has only substance units: false
boundary condition: false
initial amount: NaN
constant: false
is: SBO:0000299

097902
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

999557
stoichiometry: 1.0
species: metaid M 104
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106032
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 247
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is: SBO:0000014
constant: false
is: sce00230
type: Species
is: S000003203
initial amount: NaN
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name: YGL234W
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boundary condition: false
initial concentration: NaN

967787
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

098034
units: 958314
value: 0.0
type: LocalParameter

086826
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

037722
stoichiometry: 1.0
species: metaid M 635
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118848
stoichiometry: 1.0
species: metaid M 419
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044409
units: 958314
value: 0.00975526499984
type: LocalParameter

061120
units: 958314
value: 0.0
type: LocalParameter

139128
stoichiometry: 1.0
species: metaid M 664
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105731
stoichiometry: 1.0
species: metaid M 509
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006847
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R YPL275W
product: 120115
notes: SUBSYSTEM: Methane metabolism
fast: false
reactant: 120103
reversible: false
name: Formate dehydrogenase 2
modifier: 120139
type: Reaction
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kinetic law: 120151
is: SBO:0000176
reactant: 120091
product: 120127

085887
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

120875
stoichiometry: 1.0
species: metaid M 987
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064529
stoichiometry: 1.0
species: metaid M 191
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016461
stoichiometry: 1.0
species: metaid M 327
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metaid M 408
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is: CHEBI:15521
initial amount: NaN
boundary condition: false
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name: lauroyl-CoA
is: SBO:0000299
type: Species
initial concentration: NaN
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025291
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

013421
units: 958314
value: 0.0
type: LocalParameter

036336
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R HXT11 1
notes: SUBSYSTEM: Transport, extracellular
modifier: 026144
is: SBO:0000185
kinetic law: 026156
reversible: false
reactant: 026120
fast: false
product: 026132
type: Reaction
name: Hexose transporter HXT11

093686
units: 958314
value: 0.0
type: LocalParameter

016533
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

133682
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid R U97
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product: 104850
notes: SUBSYSTEM: Pantothenate and CoA metabolism
product: 104838
name: Dephosphocoa kinase
kinetic law: 104862
reactant: 104814
reversible: false
fast: false
is: SBO:0000176
type: Reaction
reactant: 104826

091447
stoichiometry: 1.0
species: metaid M 501
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970477
stoichiometry: 1.0
species: metaid M 779
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000472
stoichiometry: 1.0
species: metaid M 212
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metaid M 407
notes: FORMULA: C12H23OSR
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constant: false
name: dodecanoyl-[acp]
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initial concentration: NaN
initial amount: NaN
in compartment: metaid C 1
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is: SBO:0000299
type: Species

103670
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

000315
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R LYS20 2
product: 041424
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name: Homocitrate synthase, cytosolic isozyme
notes: SUBSYSTEM: Pyruvate metabolism
is: http://identifiers.org/ec-code/2.3.3.14
product: 041412
reactant: 041388
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type: Reaction
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kinetic law: 041448
reactant: 041400
modifier: 041436

105018
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species: metaid M 439
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082214
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

992249
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species: metaid M 693
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973445
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species: metaid M 660
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136993
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

025075
units: 958314
value: 0.0
type: LocalParameter

964950
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

122467
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

136102
stoichiometry: 1.0
species: metaid M 1036
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999437
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species: metaid M 218
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023546
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

035781
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value: 0.0
type: LocalParameter

055166
stoichiometry: 1.0
species: metaid M 267
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983444
units: 958314
value: 0.0
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133790
units: 958314
value: 0.0
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074811
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species: metaid M 888
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043878
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

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type: Species
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initial concentration: NaN
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notes: FORMULA: C12H23OSR
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998993
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species: metaid M 218
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001290
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

968042
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

021245
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species: metaid M 733
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metaid R LYS20 1
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type: Reaction
is: SBO:0000176
kinetic law: 041328
name: Homocitrate synthase, cytosolic isozyme
notes: SUBSYSTEM: Pyruvate metabolism
modifier: 041316
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product: 041292
reactant: 041280
reactant: 041268
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991297
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species: metaid M 693
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990301
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

020956
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

994548
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species: metaid M 692
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958397
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species: metaid M 231
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041749
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species: metaid M 693
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974324
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species: metaid M 660
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979995
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value: 1000.0
name: UPPER_BOUND
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057878
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value: 0.0
type: LocalParameter

040294
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species: metaid M 263
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015158
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species: metaid M 578
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072756
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species: metaid M 857
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metaid M 405
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initial concentration: NaN
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has only substance units: false
type: Species
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name: lauric acid
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is: SBO:0000299

015097
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R U106
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type: Reaction
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product: 085068
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kinetic law: 085080
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fast: false
reversible: false
reactant: 085044
notes: SUBSYSTEM: Nicotinic acid synthesis from TRP

041893
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species: metaid M 694
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986575
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value: 0.0
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020884
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species: metaid M 231
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121194
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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004374
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species: metaid M 501
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027731
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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991008
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value: 1000.0
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type: LocalParameter

983106
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species: metaid M 516
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metaid R U107
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name: 2-octaprenylphenol hydroxylase
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notes: SUBSYSTEM: Quinone biosynthesis
type: Reaction
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reactant: 085152
is: SBO:0000176
is: http://identifiers.org/ec-code/1.13.14.-
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127648
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species: metaid M 654
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128574
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species: metaid M 717
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017978
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species: metaid M 221
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metaid R GNP1 1
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name: High-affinity glutamine permease
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reactant: 016365
product: 016377
reactant: 016353
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058735
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value: 1000.0
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initial amount: NaN
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043673
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product: 074823
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notes: SUBSYSTEM: Fatty acid degradation

079896
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value: 0.0
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metaid E 253
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metaid R FAS2 7 2
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product: 002263
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984817
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962283
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972773
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090402
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species: metaid M 824
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metaid R SUR2
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reactant: 076270
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modifier: 076306
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type: Reaction
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095263
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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037505
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017824
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name: OBJECTIVE_COEFFICIENT
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metaid M 690
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initial concentration: NaN

096419
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002805
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metaid E 545
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is: SBO:0000014
type: Species
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initial amount: NaN
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078212
stoichiometry: 1.0
species: metaid M 217
type: SpeciesReference

metaid R SPS19 3
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fast: false
is: SBO:0000176
reactant: 074715
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product: 074727
modifier: 074739
notes: SUBSYSTEM: Fatty acid degradation
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kinetic law: 074751

111698
stoichiometry: 1.0
species: metaid M 712
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metaid E 254
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is: sce00251
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initial amount: NaN
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is: S000003251
is: sce00410
is: P17649
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069196
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species: metaid M 733
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020233
stoichiometry: 1.0
species: metaid M 744
type: SpeciesReference

127961
units: 958314
value: 0.0
type: LocalParameter

126976
stoichiometry: 1.0
species: metaid M 536
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143479
stoichiometry: 0.050027
species: metaid M 601
type: SpeciesReference

metaid R FAS2 7 1
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reversible: false
name: 3-oxoacyl-[acyl-carrier-protein] synthase
kinetic law: 002167
reactant: 002107
modifier: 002155
type: Reaction
fast: false
product: 002131
product: 002119
is: SBO:0000176
notes: SUBSYSTEM: Cytosolic fatty acid synthesis
reactant: 002095
is: http://identifiers.org/ec-code/2.3.1.41

129503
stoichiometry: 1.0
species: metaid M 785
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metaid E 250
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is: sce00530
notes: SHORT NAME: HXK2
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is: sce00052
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boundary condition: false
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is: SBO:0000014
initial amount: NaN

metaid R PFK27
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notes: SUBSYSTEM: Fructose and mannose metabolism
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modifier: 055322
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product: 055310
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reactant: 055274
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product: 055298

metaid R OPEPxtI
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product: 128743
reactant: 128730
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fast: false
reversible: false
name: Uptake of oligopeptide
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metaid R GNP1 3
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name: High-affinity glutamine permease
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reactant: 016569
type: Reaction
reversible: true
product: 016593
fast: false
kinetic law: 016617
modifier: 016605
reactant: 016581

080269
units: 958314
value: 1000.0
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123827
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metaid E 542
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has only substance units: false
constant: false
in compartment: metaid C 2
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058022
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species: metaid M 733
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961556
stoichiometry: 1.0
species: metaid M 262
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132937
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979237
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species: metaid M 616
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033057
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species: metaid M 129
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012583
units: 958314
value: 1000.0
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metaid R SPS19 6
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type: Reaction
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product: 075015
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metaid R FNADH
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reactant: 006158
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fast: false
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name: Model-specific reaction, used to affect NADH levels by converting NAD+ to NADH
type: Reaction

981898
stoichiometry: 1.0
species: metaid M 317
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metaid R PFK26
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reactant: 055166
reactant: 055154
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metaid E 251
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is: SBO:0000014
is: sce00010
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094337
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid R GLACxtO
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product: 136608
reactant: 136596
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of D-galactose
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109771
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value: 0.0
type: LocalParameter

075221
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species: metaid M 468
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062192
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid E 543
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notes: SHORT NAME: ERG8
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139284
units: 958314
value: 0.0
type: LocalParameter

metaid R GNP1 2
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product: 016485
fast: false
is: SBO:0000185
reversible: true
reactant: 016473
modifier: 016497
notes: SUBSYSTEM: Transport, extracellular
reactant: 016461

044625
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

024799
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 252
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is: sce00440
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boundary condition: false
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is: SBO:0000014
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106694
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

053746
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R SPS19 5
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kinetic law: 074943
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notes: SUBSYSTEM: Fatty acid degradation
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type: Reaction
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name: Peroxisomal 2,4-dienoyl-CoA reductase SPS19

metaid R THS1
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product: 080221
product: 080209
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reactant: 080161
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reactant: 080185
modifier: 080233
product: 080197
is: SBO:0000176
type: Reaction

100671
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species: metaid M 162
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metaid R U128
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product: 086958
reactant: 086946
notes: SUBSYSTEM: Transport, mitochondrial
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fast: false
reversible: true
name: Transport of L-threonine, mitochondrial
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958913
stoichiometry: 1.0
species: metaid M 521
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050883
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value: 0.08801663029614
type: LocalParameter

998184
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value: 0.0
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068569
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species: metaid M 183
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982516
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

021943
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

026578
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

106369
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

119657
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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994885
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species: metaid M 694
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011946
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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993200
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species: metaid M 691
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metaid E 29
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constant: false
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054360
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid M 693
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boundary condition: false
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name: NADPH
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111892
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
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name: OBJECTIVE_COEFFICIENT
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has only substance units: false
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112921
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species: metaid M 559
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111263
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value: 1000.0
name: UPPER_BOUND
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065289
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid R GNP1 5
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reactant: 016788
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reactant: 016800
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122248
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species: metaid M 275
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061988
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species: metaid M 744
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value: 0.0
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species: metaid M 44
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073983
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species: metaid M 850
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initial concentration: NaN
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boundary condition: false
initial amount: NaN
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974107
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species: metaid M 525
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104092
units: 958314
value: 0.0
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in compartment: metaid C 1
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units: 958314
value: 0.0
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033478
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species: metaid M 64
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metaid M 400
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initial amount: NaN
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boundary condition: false
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initial concentration: NaN
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metaid E 541
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type: Species
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metaid R GNP1 4
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reactant: 016678
notes: SUBSYSTEM: Transport, extracellular
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kinetic law: 016728
product: 016702
name: High-affinity glutamine permease
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078707
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

133466
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species: metaid M 281
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084063
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species: metaid M 92
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977626
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species: metaid M 230
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137790
stoichiometry: 1.0
species: metaid M 1056
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115150
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species: metaid M 223
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metaid E 255
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notes: SHORT NAME: GSC2

960208
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

085706
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

016317
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

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name: NADP(+)
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boundary condition: false
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035228
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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072069
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value: 1000.0
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type: LocalParameter

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reactant: 017018
product: 017030
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reactant: 017006
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116394
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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080559
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species: metaid M 363
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metaid M 692
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initial amount: NaN
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is: CHEBI:18009
type: Species

005689
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species: metaid M 446
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020739
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981850
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metaid R GNP1 6
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079366
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010429
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094757
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species: metaid M 282
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metaid R UAcyl 6 1
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133226
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metaid R MET6
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122357
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product: 139815
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notes: SUBSYSTEM: Exchange reactions
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reversible: false
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100022
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value: 0.0
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initial concentration: NaN
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998292
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128345
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metaid R U139
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reactant: 087936
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Transport of dethiobiotin, mitochondrial
type: Reaction

metaid M 557
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constant: false
type: Species
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initial concentration: NaN
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boundary condition: false
is: CHEBI:16467
in compartment: metaid C 2

098661
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
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973872
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species: metaid M 501
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002913
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species: metaid M 506
type: SpeciesReference

metaid M 554
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initial amount: NaN
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name: L-alanine
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in compartment: metaid C 2
boundary condition: false
is: SBO:0000299
type: Species
is: CHEBI:16977

metaid E 695
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is: SBO:0000014
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species: metaid M 1020
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metaid M 695
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is: CHEBI:17411
initial amount: NaN
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initial concentration: NaN
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metaid E 27
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in compartment: metaid C 2
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constant: false
boundary condition: false
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is: P00817
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974215
stoichiometry: 1.0
species: metaid M 632
type: SpeciesReference

128285
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R FAA4 4
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reactant: 996917
kinetic law: 996979
product: 996929
fast: false
product: 996942
notes: SUBSYSTEM: Fatty acid biosynthesis
reactant: 996905
reversible: false
type: Reaction
product: 996955
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reactant: 996893
is: SBO:0000176

005533
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

027527
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

080669
stoichiometry: 1.0
species: metaid M 337
type: SpeciesReference

036119
units: 958314
value: 0.0
type: LocalParameter

072177
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

095034
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

117318
stoichiometry: 1.0
species: metaid M 230
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032745
stoichiometry: 1.0
species: metaid M 319
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metaid E 696
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boundary condition: false
type: Species
initial amount: NaN
constant: false
has only substance units: false
in compartment: metaid C 2
initial concentration: NaN
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is: P32178
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079475
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

057504
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R RKI1
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kinetic law: 069087
reactant: 069051
reversible: true
is: SBO:0000176
fast: false
is: http://identifiers.org/ec-code/5.3.1.6
notes: SUBSYSTEM: Pentose phosphate pathway
name: Ribose-5-phosphate isomerase
product: 069063
modifier: 069075

metaid R MET7
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fast: false
is: SBO:0000176
modifier: 044963
name: Folylpolyglutamate synthase
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type: Reaction
product: 044938
reactant: 044902
is: http://identifiers.org/ec-code/6.3.2.17
notes: SUBSYSTEM: Folate metabolism
reversible: true
kinetic law: 044975
product: 044950
product: 044926

metaid M 555
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constant: false
initial amount: NaN
initial concentration: NaN
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has only substance units: false
is: CHEBI:16977
name: L-alanine
is: SBO:0000299
in compartment: metaid C 1

105176
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

032672
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 26
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in compartment: metaid C 2
has only substance units: false
initial amount: NaN
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is: P38067
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is: sce00650
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boundary condition: false
is: S000000210
is: sce00251
is: sce00350

095709
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R FAA4 3
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is: http://identifiers.org/ec-code/6.2.1.3
reactant: 996773
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is: SBO:0000176
reversible: false
name: Long-chain-fatty-acid--CoA ligase 4
kinetic law: 996833
product: 996809
modifier: 996821
reactant: 996761
notes: SUBSYSTEM: Fatty acid biosynthesis
product: 996797
reactant: 996749
type: Reaction

058843
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 696
is: SBO:0000299
constant: false
notes: FORMULA: C6H8N2O4R2(C2H2NOR)n
name: Nalpha-acetylpeptide
is: C03011
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type: Species
initial concentration: NaN
boundary condition: false
in compartment: metaid C 2
initial amount: NaN

metaid R SPRMxtI
kinetic law: 130358
product: 130346
reactant: 130334
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of spermine
type: Reaction

099481
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

060301
stoichiometry: 1.0
species: metaid M 355
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035337
units: 958314
value: 1.8924515935998
type: LocalParameter

metaid R HXT4 4
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kinetic law: 028762
modifier: 028750
is: SBO:0000185
type: Reaction
notes: SUBSYSTEM: Transport, extracellular
fast: false
reversible: false
name: Low-affinity glucose transporter HXT4
reactant: 028726

099106
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species: metaid M 698
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977518
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species: metaid M 795
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978288
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R FAA4 2
product: 996653
reactant: 996617
name: Long-chain-fatty-acid--CoA ligase 4
product: 996641
kinetic law: 996689
notes: SUBSYSTEM: Fatty acid biosynthesis
fast: false
type: Reaction
reactant: 996629
is: http://identifiers.org/ec-code/6.2.1.3
reversible: false
product: 996665
is: SBO:0000176
reactant: 996605
modifier: 996677

metaid R MET2
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product: 044457
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fast: false
is: SBO:0000176
name: Homoserine O-acetyltransferase
modifier: 044469
reactant: 044433
product: 044445
type: Reaction
kinetic law: 044481
notes: SUBSYSTEM: Cysteine metabolism

981742
stoichiometry: 1.0
species: metaid M 300
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metaid E 548
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initial amount: NaN
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notes: SHORT NAME: URA10
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has only substance units: false
is: S000004884
boundary condition: false
type: Species
initial concentration: NaN
is: P30402
name: YMR271C
constant: false

078104
stoichiometry: 1.0
species: metaid M 217
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098889
stoichiometry: 1.0
species: metaid M 578
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079787
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

142779
stoichiometry: 1.0
species: metaid M 1115
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134514
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid M 552
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initial concentration: NaN
initial amount: NaN
is: CHEBI:17917
in compartment: metaid C 2
is: SBO:0000299
has only substance units: false
boundary condition: false
constant: false
type: Species

987140
units: 958314
value: 0.0
type: LocalParameter

109663
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species: metaid M 262
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042901
stoichiometry: 1.0
species: metaid M 698
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139803
stoichiometry: 1.0
species: metaid M 729
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is: P38169
initial concentration: NaN
is: S000000194
is: SBO:0000014
name: YBL098W
has only substance units: false
initial amount: NaN
type: Species
constant: false
boundary condition: false

metaid R MET1
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name: Uroporphyrinogen-III C-methyltransferase
is: http://identifiers.org/ec-code/2.1.1.107
is: SBO:0000176
notes: SUBSYSTEM: Porphyrin metabolism
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reactant: 043323
kinetic law: 043384
fast: false
type: Reaction
product: 043360
modifier: 043372
product: 043348

metaid E 549
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type: Species
notes: SHORT NAME: SCS7
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initial concentration: NaN
constant: false
is: SBO:0000014
initial amount: NaN
is: Q03529
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metaid R FAA4 1
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modifier: 996533
reactant: 996485
is: SBO:0000176
fast: false
reversible: false
reactant: 996461
name: Long-chain-fatty-acid--CoA ligase 4
notes: SUBSYSTEM: Fatty acid biosynthesis
kinetic law: 996545
product: 996521
product: 996497
product: 996509
type: Reaction
is: http://identifiers.org/ec-code/6.2.1.3

110011
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

123562
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

096528
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

124658
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

078634
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species: metaid M 928
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metaid M 553
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constant: false
initial amount: NaN
type: Species
is: C15556
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is: SBO:0000299
name: 3,4-dihydroxy-2-butanone 4-phosphate
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initial concentration: NaN

060748
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

123935
stoichiometry: 1.0
species: metaid M 372
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984227
stoichiometry: 1.0
species: metaid M 698
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086225
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

048313
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

027948
stoichiometry: 1.0
species: metaid M 451
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metaid R U118
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product: 086103
reactant: 086091
notes: SUBSYSTEM: Transport, mitochondrial
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fast: false
reversible: true
name: Transport of 3-isopropylmalate, mitochondrial
type: Reaction

095372
stoichiometry: 1.0
species: metaid M 235
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112324
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 20
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notes: SHORT NAME: ILS1
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is: sce00970
is: sce00290
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972664
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

992672
units: 958314
value: 0.00263835
type: LocalParameter

066210
units: 958314
value: 0.0
type: LocalParameter

metaid E 546
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constant: false
has only substance units: false
notes: SHORT NAME: TPS3
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initial amount: NaN
is: S000004874
boundary condition: false
initial concentration: NaN
type: Species
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name: YMR261C
is: sce00500

053854
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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type: Species
name: NH3
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initial amount: NaN
in compartment: metaid C 1
has only substance units: false
constant: false
is: SBO:0000299

082865
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species: metaid M 820
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124514
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species: metaid M 1030
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101307
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species: metaid M 744
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is: SBO:0000014
boundary condition: false
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initial amount: NaN
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notes: SHORT NAME: TKL1
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is: sce00710
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metaid M 550
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initial amount: NaN
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in compartment: metaid C 2
name: L-1-pyrroline-3-hydroxy-5-carboxylate
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type: Species
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962367
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species: metaid M 44
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112216
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

114440
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species: metaid M 857
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058131
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species: metaid M 501
type: SpeciesReference

metaid R SPS19 2
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reactant: 074610
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product: 074623
notes: SUBSYSTEM: Fatty acid degradation
kinetic law: 074649
fast: false
is: SBO:0000176
type: Reaction
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metaid E 23
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initial concentration: NaN
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initial amount: NaN
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notes: SHORT NAME: NTH2
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is: S000000205
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969911
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species: metaid M 842
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984925
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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019655
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species: metaid M 461
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metaid R ACxtO
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product: 132043
reactant: 132031
notes: SUBSYSTEM: Exchange reactions
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fast: false
reversible: false
name: Excretion of acetate
type: Reaction

007016
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

024642
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species: metaid M 246
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974975
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species: metaid M 131
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R MET3
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reactant: 044661
product: 044685
product: 044673
type: Reaction
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reactant: 044649
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notes: SUBSYSTEM: Cysteine metabolism
name: Sulfate adenylyltransferase
modifier: 044697

016039
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

012475
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

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is: S000004880
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initial concentration: NaN
in compartment: metaid C 2
constant: false
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initial amount: NaN
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metaid M 551
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has only substance units: false
in compartment: metaid C 2
is: SBO:0000299
initial concentration: NaN
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961448
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species: metaid M 691
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fast: false
reactant: 097566
product: 097578
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kinetic law: 097602
product: 097590
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notes: SUBSYSTEM: Salvage pathways
type: Reaction
is: http://identifiers.org/ec-code/3.1.3.5

133887
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species: metaid M 287
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081781
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species: metaid M 668
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020125
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species: metaid M 318
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126868
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value: 0.0
type: LocalParameter

061831
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

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name: YBL099W
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notes: SHORT NAME: ATP1
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is: SBO:0000014
initial amount: NaN
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type: Species
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metaid R SPS19 1
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kinetic law: 074548
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type: Reaction
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reactant: 074512
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reversible: false
is: http://identifiers.org/ec-code/1.3.1.34
name: Peroxisomal 2,4-dienoyl-CoA reductase SPS19

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species: metaid M 1091
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047231
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species: metaid M 254
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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species: metaid M 346
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983541
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value: 0.0
type: LocalParameter

099275
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value: 0.0
type: LocalParameter

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is: SBO:0000014
initial concentration: NaN
initial amount: NaN
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069256
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

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reversible: false
kinetic law: 115066

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value: 0.0
name: LOWER_BOUND
type: LocalParameter

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is: http://identifiers.org/ec-code/1.1.1.284
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product: 072660
product: 072647
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modifier: 072672
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reactant: 072635
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137054
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value: 0.0
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type: LocalParameter

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species: metaid M 744
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value: 1000.0
name: UPPER_BOUND
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value: 0.0
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035903
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099335
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species: metaid M 689
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metaid R YGL186C 2
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product: 115150
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reactant: 115138
kinetic law: 115175
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initial amount: NaN
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961992
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species: metaid M 733
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028033
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name: L-threonine dehydratase
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

141792
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

086501
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value: 0.37549115831233
type: LocalParameter

143587
stoichiometry: 0.82099
species: metaid M 648
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990638
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

metaid R U116
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product: 085935
reactant: 085923
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Transport of L-serine, mitochondrial
type: Reaction

metaid R YGL186C 3
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fast: false
kinetic law: 115284
notes: SUBSYSTEM: Transport, extracellular
modifier: 115271
is: SBO:0000185
product: 115259
reactant: 115235
name: Vitamin B6 transporter TPN1
type: Reaction
reactant: 115247

033490
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species: metaid M 694
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026216
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species: metaid M 468
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metaid E 40
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has only substance units: false
notes: SHORT NAME: BAP2
type: Species
is: S000000272
boundary condition: false
initial concentration: NaN
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constant: false
is: P38084
is: SBO:0000014
initial amount: NaN

133142
stoichiometry: 1.0
species: metaid M 1001
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983010
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species: metaid M 569
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981032
stoichiometry: 1.0
species: metaid M 830
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973734
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

958384
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species: metaid M 733
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metaid E 109
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initial amount: NaN
type: Species
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has only substance units: false
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constant: false
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962574
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R FAB1
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is: SBO:0000176
reactant: 997195
fast: false
reactant: 997183
kinetic law: 997243
notes: SUBSYSTEM: Phospholipid biosynthesis
reversible: false
modifier: 997231
product: 997219
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.150
name: 1-phosphatidylinositol-3-phosphate 5-kinase FAB1

120755
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

970598
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species: metaid M 624
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055046
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species: metaid M 267
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006401
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

131995
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

144155
stoichiometry: 0.153
species: metaid M 559
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138416
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

082335
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 41
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name: YBR069C
is: P38085
initial concentration: NaN
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998895
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species: metaid M 408
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972095
units: 958314
value: 2.574E-5
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005761
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

122563
units: 958314
value: 0.0
type: LocalParameter

metaid R SFA1 1
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is: SBO:0000176
reactant: 072491
product: 072539
reactant: 072503
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kinetic law: 072563
modifier: 072551
product: 072527
reactant: 072515
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notes: SUBSYSTEM: Pyruvate metabolism
fast: false
reversible: true

049870
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species: metaid M 241
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010862
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

090102
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species: metaid M 501
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metaid E 108
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notes: SHORT NAME: QRI1
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068581
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species: metaid M 553
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054348
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value: 1000.0
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101802
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species: metaid M 37
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067607
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species: metaid M 192
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081622
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R TRP3 2
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type: Reaction
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product: 082262
modifier: 082286
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fast: false
is: http://identifiers.org/ec-code/4.1.1.48
kinetic law: 082299
product: 082274
notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)

006703
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species: metaid M 400
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061024
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species: metaid M 321
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106237
stoichiometry: 1.0
species: metaid M 889
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metaid R EPT1
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is: SBO:0000176
modifier: 990971
product: 990945
name: Choline/ethanolaminephosphotransferase 1
notes: SUBSYSTEM: Phospholipid biosynthesis
reactant: 990932
is: http://identifiers.org/ec-code/2.7.8.1
fast: false
kinetic law: 990984
product: 990958
reversible: true
reactant: 990919

036576
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R HOM6 1
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reactant: 022978
reactant: 022966
product: 022990
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notes: SUBSYSTEM: Glycine, serine, and threonine metabolism
modifier: 023015
type: Reaction
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product: 023003
kinetic law: 023027
is: http://identifiers.org/ec-code/1.1.1.3

080995
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value: 1000.0
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type: LocalParameter

995681
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

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constant: false
initial concentration: NaN
type: Species
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is: SBO:0000299
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boundary condition: false

metaid E 691
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type: Species
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initial amount: NaN
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notes: SHORT NAME: AGC1
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102331
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species: metaid M 165
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is: sce00500
has only substance units: false
in compartment: metaid C 2
type: Species
boundary condition: false
constant: false
is: SBO:0000014
initial amount: NaN
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metaid E 103
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is: SBO:0000014
notes: SHORT NAME: NDE2
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is: sce00190
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boundary condition: false
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016245
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species: metaid M 318
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087391
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value: 0.0
type: LocalParameter

101536
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid R TRP3 3
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notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
product: 082372
is: SBO:0000176
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kinetic law: 082408
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product: 082384
reactant: 082360
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031803
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R HOM6 2
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is: SBO:0000176
product: 023112
modifier: 023137
type: Reaction
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reactant: 023100
notes: SUBSYSTEM: Glycine, serine, and threonine metabolism
reactant: 023088
product: 023124
kinetic law: 023150
fast: false

metaid R HYR1
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name: Peroxiredoxin HYR1
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modifier: 030402
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product: 030390
type: Reaction
reactant: 030378
is: http://identifiers.org/ec-code/1.11.1.15
reversible: true

105876
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value: 0.08296592527666
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963201
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species: metaid M 253
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099914
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species: metaid M 687
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initial concentration: NaN
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metaid M 546
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in compartment: metaid C 1
initial amount: NaN
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is: CHEBI:15528
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type: Species

988092
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

078863
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species: metaid M 154
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metaid E 102
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is: P32419
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is: sce00620
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name: YDL078C
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initial concentration: NaN

076198
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

119173
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species: metaid M 262
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985324
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species: metaid M 613
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969706
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

064867
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species: metaid M 249
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080281
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

001830
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value: 0.0
type: LocalParameter

142237
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid M 549
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name: potassium
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initial concentration: NaN
is: SBO:0000299
is: CHEBI:26216
initial amount: NaN
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boundary condition: false

131851
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value: 0.0
type: LocalParameter

metaid R FORxtI
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product: 125031
reactant: 125019
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of formate
type: Reaction

984372
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

126159
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

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species: metaid M 972
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112372
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species: metaid M 341
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999677
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species: metaid M 508
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109458
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species: metaid M 461
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040150
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

043311
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value: 0.0
type: LocalParameter

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has only substance units: false
type: Species
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is: P32288
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079607
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111553
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species: metaid M 713
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value: 0.0
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metaid R TRP3 1
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notes: SUBSYSTEM: Phenylalanine, tyrosine, and tryptophan biosynthesis (aromatic amino acids)
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965588
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value: 1000.0
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005002
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value: 0.0
type: LocalParameter

129731
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value: 0.0
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118559
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value: 0.67379949000006
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constant: false
type: Species
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value: 0.0
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080125
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value: 1000.0
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value: 1000.0
name: UPPER_BOUND
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value: -1000.0
name: LOWER_BOUND
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name: OBJECTIVE_COEFFICIENT
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initial amount: NaN
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959760
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species: metaid M 214
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141042
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value: 1000.0
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species: metaid M 959
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123418
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species: metaid M 1017
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974817
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value: 1000.0
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

040006
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

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initial amount: NaN
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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129671
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species: metaid M 821
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012790
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

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species: metaid M 501
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

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species: metaid M 878
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003348
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species: metaid M 321
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987248
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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119065
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species: metaid M 412
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metaid R TAL1
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modifier: 076426
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product: 076402
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value: 0.0
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982721
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value: 1000.0
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995790
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959337
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value: 1000.0
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071524
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050654
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130068
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140970
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type: LocalParameter

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106020
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value: 1000.0
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086838
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099806
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metaid R U96
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006859
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037710
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061132
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124080
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043468
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048084
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959650
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metaid R GUT1
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085007
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metaid R YPL276W
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991141
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135908
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109566
stoichiometry: 1.0
species: metaid M 230
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126267
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

028521
units: 958314
value: 0.0
type: LocalParameter

093650
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

977854
stoichiometry: 1.0
species: metaid M 698
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121180
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

108820
stoichiometry: 1.0
species: metaid M 230
type: SpeciesReference

036468
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

027961
stoichiometry: 1.0
species: metaid M 338
type: SpeciesReference

106526
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

141152
units: 958314
value: 0.0
type: LocalParameter

007451
stoichiometry: 1.0
species: metaid M 107
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064421
stoichiometry: 1.0
species: metaid M 253
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985745
stoichiometry: 1.0
species: metaid M 859
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023558
units: 958314
value: 0.0
type: LocalParameter

999425
stoichiometry: 1.0
species: metaid M 870
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961884
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

973433
stoichiometry: 1.0
species: metaid M 501
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122455
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

136981
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

025063
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R FAS1 2 2
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kinetic law: 997919
modifier: 997907
fast: false
is: http://identifiers.org/ec-code/1.3.1.9
is: SBO:0000176
product: 997883
name: Enoyl-[acyl-carrier-protein] reductase [NADH]
reactant: 997871
notes: SUBSYSTEM: Cytosolic fatty acid synthesis
reactant: 997859
type: Reaction
product: 997895

968030
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

021233
stoichiometry: 1.0
species: metaid M 584
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006630
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

020944
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

071669
stoichiometry: 1.0
species: metaid M 411
type: SpeciesReference

990313
units: 958314
value: 0.04086069000001
type: LocalParameter

034818
stoichiometry: 1.0
species: metaid M 40
type: SpeciesReference

983432
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

055154
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

025399
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

093504
stoichiometry: 1.0
species: metaid M 393
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043239
stoichiometry: 1.0
species: metaid M 795
type: SpeciesReference

008695
stoichiometry: 1.0
species: metaid M 116
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986587
stoichiometry: 1.0
species: metaid M 501
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974312
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

069364
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R FAS1 2 1
type: Reaction
reversible: false
product: 997775
reactant: 997763
notes: SUBSYSTEM: Cytosolic fatty acid synthesis
name: 3-hydroxyacyl-[acyl-carrier-protein] dehydrase
modifier: 997787
is: SBO:0000176
is: http://identifiers.org/ec-code/4.2.1.61
kinetic law: 997799
fast: false

095997
stoichiometry: 1.0
species: metaid M 972
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020872
stoichiometry: 1.0
species: metaid M 318
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072768
stoichiometry: 1.0
species: metaid M 453
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085875
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

090210
stoichiometry: 1.0
species: metaid M 695
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101958
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

089404
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

093699
stoichiometry: 1.0
species: metaid M 372
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036348
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

016473
stoichiometry: 1.0
species: metaid M 501
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994440
stoichiometry: 1.0
species: metaid M 692
type: SpeciesReference

120863
units: 958314
value: 0.0
type: LocalParameter

981141
stoichiometry: 1.0
species: metaid M 98
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013433
stoichiometry: 1.0
species: metaid M 483
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068690
stoichiometry: 1.0
species: metaid M 48
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992382
stoichiometry: 1.0
species: metaid M 537
type: SpeciesReference

016545
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

990421
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

000303
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

082226
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

992237
stoichiometry: 1.0
species: metaid M 152
type: SpeciesReference

133670
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

982068
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

091459
stoichiometry: 1.0
species: metaid M 982
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051508
stoichiometry: 1.0
species: metaid M 507
type: SpeciesReference

metaid R U105
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fast: false
reactant: 084947
is: SBO:0000176
kinetic law: 084983
reversible: false
product: 084959
name: NADP phosphatase
notes: SUBSYSTEM: Nicotinic acid synthesis from TRP
is: http://identifiers.org/ec-code/3.1.2.-
product: 084971

103682
units: 958314
value: 0.0
type: LocalParameter

000460
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species: metaid M 218
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metaid R U127
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is: SBO:0000185
fast: false
kinetic law: 086886
product: 086874
notes: SUBSYSTEM: Transport, mitochondrial
name: Transport of sulfate, mitochondrial
reactant: 086850
product: 086862
type: Reaction

metaid R ASPxtO
kinetic law: 132985
product: 132973
reactant: 132961
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of L-aspartate
type: Reaction

020245
stoichiometry: 2.0
species: metaid M 318
type: SpeciesReference

127973
stoichiometry: 1.0
species: metaid M 1071
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126964
stoichiometry: 1.0
species: metaid M 1059
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106129
units: 958314
value: 0.0
type: LocalParameter

143467
stoichiometry: 0.23942
species: metaid M 597
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metaid E 262
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initial concentration: NaN
name: YGR088W
in compartment: metaid C 2
type: Species
is: sce00680
constant: false
notes: SHORT NAME: CTT1
is: P06115
is: S000003320
boundary condition: false
is: sce00380
is: SBO:0000014
has only substance units: false

012571
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid E 263
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is: sce00290
has only substance units: false
initial amount: NaN
constant: false
type: Species
name: YGR094W
is: sce00970
is: S000003326
initial concentration: NaN
is: SBO:0000014
boundary condition: false
is: P07806

057890
stoichiometry: 1.0
species: metaid M 351
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123839
stoichiometry: 1.0
species: metaid M 1022
type: SpeciesReference

134188
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 530
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type: Species
is: S000004711
is: sce00052
is: sce00010
notes: SHORT NAME: PGM2
is: SBO:0000014
is: sce00030
initial concentration: NaN
constant: false
boundary condition: false
is: sce00500
is: P37012
name: YMR105C
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132949
units: 958314
value: 0.0
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979225
units: 958314
value: 0.08296592527666
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961544
units: 958314
value: 0.13936337999979
type: LocalParameter

033045
stoichiometry: 1.0
species: metaid M 4
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113703
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

062180
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

109783
stoichiometry: 1.0
species: metaid M 263
type: SpeciesReference

metaid R FAA3 1
reactant: 996164
notes: SUBSYSTEM: Fatty acid biosynthesis
reversible: false
type: Reaction
product: 996212
fast: false
product: 996200
kinetic law: 996248
modifier: 996236
is: http://identifiers.org/ec-code/6.2.1.3
name: Long-chain-fatty-acid--CoA ligase 3
product: 996224
is: SBO:0000176
reactant: 996176
reactant: 996188

108603
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

035769
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

010717
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

001109
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species: metaid M 218
type: SpeciesReference

metaid E 264
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initial concentration: NaN
constant: false
boundary condition: false
type: Species
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name: YGR096W
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in compartment: metaid C 2
notes: SHORT NAME: TPC1
has only substance units: false

053758
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

106682
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R FAA3 2
kinetic law: 996399
notes: SUBSYSTEM: Fatty acid biosynthesis
reactant: 996309
product: 996373
product: 996360
reversible: false
type: Reaction
product: 996347
name: Long-chain-fatty-acid--CoA ligase 3
reactant: 996334
reactant: 996322
is: SBO:0000176
modifier: 996386
is: http://identifiers.org/ec-code/6.2.1.3
fast: false

123731
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

044613
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 531
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boundary condition: false
in compartment: metaid C 2
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is: sce00770
notes: SHORT NAME: ILV2
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is: sce00290
initial amount: NaN
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is: S000004714
has only substance units: false

003566
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

139296
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species: metaid M 695
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983891
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species: metaid M 239
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141369
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

034284
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species: metaid M 733
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127636
stoichiometry: 1.0
species: metaid M 1067
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027743
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value: 0.0
type: LocalParameter

983118
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species: metaid M 613
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047379
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species: metaid M 254
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969294
stoichiometry: 1.0
species: metaid M 672
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004386
stoichiometry: 1.0
species: metaid M 497
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110179
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

034975
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 265
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is: P40260
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is: S000003353
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has only substance units: false
name: YGR121C
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is: SBO:0000014
initial concentration: NaN
notes: SHORT NAME: MEP1
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017837
units: 958314
value: 4.202447509718
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128562
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species: metaid M 1078
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metaid R ETHxtO
kinetic law: 135945
product: 135933
reactant: 135920
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of ethanol
type: Reaction

018919
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species: metaid M 733
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metaid E 532
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type: Species
is: S000004719
initial concentration: NaN
initial amount: NaN
constant: false
has only substance units: false
in compartment: metaid C 2
name: YMR113W

043685
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species: metaid M 178
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027803
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

090414
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species: metaid M 354
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095251
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

118403
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

984829
units: 958314
value: 0.0
type: LocalParameter

972761
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

019535
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species: metaid M 390
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078224
stoichiometry: 1.0
species: metaid M 429
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042804
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species: metaid M 735
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metaid E 266
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initial concentration: NaN
has only substance units: false
type: Species
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is: sce00910
is: P49090
is: sce00252
notes: SHORT NAME: ASN2
initial amount: NaN
is: S000003356
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012679
units: 958314
value: -1000.0
name: LOWER_BOUND
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metaid E 533
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has only substance units: false
in compartment: metaid C 2
name: YMR120C
initial concentration: NaN
is: S000004727
is: SBO:0000014
type: Species
initial amount: NaN
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is: P38009
notes: SHORT NAME: ADE17
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009094
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species: metaid M 795
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078719
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

133454
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value: 0.0
type: LocalParameter

963871
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

095155
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

977638
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species: metaid M 412
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metaid R GUT2
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product: 019885
type: Reaction
name: Glycerol-3-phosphate dehydrogenase, mitochondrial
modifier: 019909
is: http://identifiers.org/ec-code/1.1.99.5
notes: SUBSYSTEM: Glycerol metabolism (glycerolipid metabolism)
fast: false
product: 019897
reversible: false
kinetic law: 019921
is: SBO:0000176
reactant: 019861

977025
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species: metaid M 308
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016329
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid E 267
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in compartment: metaid C 2
constant: false
type: Species
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is: S000003357
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is: SBO:0000014
initial amount: NaN

995078
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

042497
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R HFA1
type: Reaction
kinetic law: 020932
reactant: 020848
modifier: 020920
is: http://identifiers.org/ec-code/6.4.1.2
product: 020884
reactant: 020860
reversible: true
name: Acetyl-CoA carboxylase, mitochondrial
fast: false
reactant: 020872
product: 020908
notes: SUBSYSTEM: Fatty acid biosynthesis
product: 020896
is: SBO:0000176

072057
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

069797
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species: metaid M 364
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079354
stoichiometry: 1.0
species: metaid M 71
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metaid R MSW1
reactant: 047219
name: Tryptophanyl-tRNA synthetase, mitochondrial
reactant: 047207
product: 047243
type: Reaction
reversible: false
notes: SUBSYSTEM: tRNA synthesis
fast: false
reactant: 047195
is: http://identifiers.org/ec-code/6.1.1.2
product: 047231
kinetic law: 047279
product: 047255
modifier: 047267
is: SBO:0000176

094613
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

020727
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

089620
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species: metaid M 501
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981862
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species: metaid M 305
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128141
stoichiometry: 1.0
species: metaid M 1073
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058722
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 268
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constant: false
type: Species
initial concentration: NaN
notes: SHORT NAME: NAT2
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initial amount: NaN
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has only substance units: false
name: YGR147C
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998172
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

982504
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

021955
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value: 0.02926599
type: LocalParameter

139984
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species: metaid M 1082
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106357
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

960913
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species: metaid M 35
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119669
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value: 0.0
type: LocalParameter

958925
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species: metaid M 698
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050871
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

016690
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species: metaid M 632
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111251
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

083709
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species: metaid M 691
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061976
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species: metaid M 723
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131706
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species: metaid M 983
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metaid R PIK1
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modifier: 057015
notes: SUBSYSTEM: Phospholipid biosynthesis
reactant: 056976
product: 056989
product: 057002
reversible: false
kinetic law: 057028
is: http://identifiers.org/ec-code/2.7.1.67
name: Phosphatidylinositol 4-kinase PIK1
is: SBO:0000176
type: Reaction

122236
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species: metaid M 1003
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011958
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value: 0.0
type: LocalParameter

metaid E 269
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initial amount: NaN
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notes: SHORT NAME: CYS4

metaid R GPM2
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notes: SUBSYSTEM: Glycolysis / Gluconeogenesis
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is: http://identifiers.org/ec-code/5.4.2.1
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kinetic law: 017690
modifier: 017678
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product: 017666

084050
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species: metaid M 779
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114500
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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048470
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type: LocalParameter

metaid R CO2xtO
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product: 134489
reactant: 134477
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of CO2
type: Reaction

969851
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

030426
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

994872
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value: 0.08807001836371
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metaid E 110
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005545
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value: 0.0
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128297
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type: LocalParameter

metaid R ETHxtI
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product: 124862
reactant: 124850
notes: SUBSYSTEM: Exchange reactions
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reversible: false
name: Uptake of ethanol
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has only substance units: false
boundary condition: false
type: Species
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032685
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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974203
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notes: SHORT NAME: ERG2
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metaid E 683
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species: metaid M 253
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initial amount: NaN
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species: metaid M 976
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constant: false
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reversible: false
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082118
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026360
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is: sce00910
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product: 121908
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fast: false
reversible: false
name: Uptake of L-aspartate
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value: 0.0
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initial concentration: NaN
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065120
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species: metaid M 762
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007337
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species: metaid M 900
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value: 0.0
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species: metaid M 949
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species: metaid M 216
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species: metaid M 1072
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961435
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species: metaid M 177
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species: metaid M 94
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066222
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species: metaid M 237
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value: 0.0
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value: 1000.0
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is: sce00350
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is: sce00450
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007028
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value: 0.0
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000604
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species: metaid M 218
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112228
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value: 0.0
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initial concentration: NaN
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species: metaid M 131
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species: metaid M 348
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value: -1000.0
name: LOWER_BOUND
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modifier: 994018
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is: sce00340
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072309
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value: 1000.0
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is: S000000233
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species: metaid M 323
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species: metaid M 733
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species: metaid M 321
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value: 1000.0
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initial amount: NaN
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species: metaid M 712
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value: 0.0
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initial amount: NaN
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reactant: 994090
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kinetic law: 994126
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has only substance units: false
initial amount: NaN
initial concentration: NaN
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057204
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value: 9.2235000001E-4
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product: 007052
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metaid M 535
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050799
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species: metaid M 692
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product: 103272
product: 103284

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value: 1000.0
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product: 124104
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value: 1000.0
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013554
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992261
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species: metaid M 293
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value: 0.0
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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value: 0.046572045
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species: metaid M 253
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species: metaid M 568
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981718
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998702
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value: 1000.0
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086802
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product: 126639
reactant: 126627
notes: SUBSYSTEM: Exchange reactions
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fast: false
reversible: false
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959919
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119053
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003312
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966286
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value: 1000.0
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000183
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061144
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125199
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139043
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species: metaid M 663
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077791
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116369
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product: 007549

115126
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014398
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value: 1000.0
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122224
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064650
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138440
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initial concentration: NaN
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118680
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value: -9.9957000028E-4
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111287
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value: 0.0
type: LocalParameter

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reactant: 048241
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value: 0.0
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type: LocalParameter

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boundary condition: false
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is: CHEBI:23929
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initial amount: NaN
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968847
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species: metaid M 669
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969028
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value: 1000.0
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type: LocalParameter

998160
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

026554
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type: LocalParameter

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species: metaid M 751
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080681
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species: metaid M 363
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name: OBJECTIVE_COEFFICIENT
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initial amount: NaN
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kinetic law: 048421
product: 048397
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modifier: 048409
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type: Reaction

114536
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species: metaid M 733
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111408
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value: 0.0
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species: metaid M 442
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value: 1000.0
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128478
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species: metaid M 1077
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product: 129419
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boundary condition: false
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species: metaid M 205
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fast: false
reactant: 005134
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reactant: 089704
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initial concentration: NaN
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initial concentration: NaN
initial amount: NaN
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boundary condition: false
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value: 0.0
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species: metaid M 659
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value: 1000.0
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species: metaid M 321
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product: 128321
reactant: 128309
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reversible: false
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value: 0.11074050000016
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type: LocalParameter

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initial amount: NaN

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value: 1000.0
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boundary condition: false
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value: 0.1789848728927
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species: metaid M 473
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metaid E 677
is: P41835
boundary condition: false
initial concentration: NaN
is: sce00730
name: YPL214C
notes: SHORT NAME: THI6
constant: false
is: S000006135
is: SBO:0000014
has only substance units: false
in compartment: metaid C 2
initial amount: NaN
type: Species

053650
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R CDC8
reactant: 977602
is: SBO:0000176
product: 977626
product: 977638
kinetic law: 977662
fast: false
is: http://identifiers.org/ec-code/2.7.4.9
modifier: 977650
name: Thymidylate kinase
type: Reaction
reactant: 977614
notes: SUBSYSTEM: Pyrimidine metabolism
reversible: true

058868
units: 958314
value: 0.08004652499994
type: LocalParameter

027924
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R FRUxtI
kinetic law: 125127
product: 125115
reactant: 125103
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of D-fructose
type: Reaction

141489
units: 958314
value: 0.0
type: LocalParameter

095396
stoichiometry: 1.0
species: metaid M 83
type: SpeciesReference

112348
units: 958314
value: 0.0
type: LocalParameter

metaid R ECM17
reactant: 988417
reactant: 988404
name: Sulfite reductase [NADPH] subunit beta
fast: false
notes: SUBSYSTEM: Cysteine metabolism
product: 988429
product: 988441
modifier: 988453
reversible: true
is: SBO:0000176
type: Reaction
is: http://identifiers.org/ec-code/1.8.1.2
kinetic law: 988465

992696
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

metaid R PDE2 5
kinetic law: 053818
reversible: false
is: http://identifiers.org/ec-code/3.1.4.17
name: 3',5'-cyclic-nucleotide phosphodiesterase 2
modifier: 053806
type: Reaction
is: SBO:0000176
product: 053794
fast: false
reactant: 053782
notes: SUBSYSTEM: Purine metabolism

metaid R NIT2 1
modifier: 049111
fast: false
product: 049099
type: Reaction
kinetic law: 049123
product: 049087
is: http://identifiers.org/ec-code/3.5.-.-
name: Probable hydrolase NIT2
is: SBO:0000176
reversible: false
reactant: 049075
notes: SUBSYSTEM: Nitrogen metabolism

metaid E 44
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is: SBO:0000014
has only substance units: false
initial amount: NaN
type: Species
initial concentration: NaN
is: S000000319
in compartment: metaid C 2
is: P07702
boundary condition: false
is: sce00310
notes: SHORT NAME: LYS2
constant: false
is: sce00300

959638
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

metaid R TKL1 2
notes: SUBSYSTEM: Pentose phosphate pathway
reactant: 080426
name: Transketolase 1
kinetic law: 080487
is: http://identifiers.org/ec-code/2.2.1.1
reactant: 080438
product: 080462
fast: false
modifier: 080475
product: 080450
reversible: true
type: Reaction
is: SBO:0000176

metaid E 678
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initial concentration: NaN
constant: false
is: P19097
is: SBO:0000014
is: S000006152
has only substance units: false
name: YPL231W
type: Species
boundary condition: false
is: sce01040
notes: SHORT NAME: FAS2
initial amount: NaN
is: sce00061

998858
stoichiometry: 1.0
species: metaid M 321
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082733
stoichiometry: 1.0
species: metaid M 691
type: SpeciesReference

110035
stoichiometry: 1.0
species: metaid M 583
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069063
stoichiometry: 1.0
species: metaid M 356
type: SpeciesReference

078610
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 121
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name: YDR007W
is: SBO:0000014
is: sce00400
has only substance units: false
constant: false
boundary condition: false
initial concentration: NaN
notes: SHORT NAME: TRP1
initial amount: NaN
is: P00912
type: Species
is: S000002414

143080
stoichiometry: 6.97E-4
species: metaid M 762
type: SpeciesReference

metaid R YIL145C
reactant: 116442
is: SBO:0000176
name: Pantoate--beta-alanine ligase
reactant: 116418
notes: SUBSYSTEM: Pantothenate and CoA metabolism
fast: false
product: 116478
product: 116466
reactant: 116430
product: 116454
type: Reaction
reversible: false
kinetic law: 116502
is: http://identifiers.org/ec-code/6.3.2.1
modifier: 116490

060724
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

961422
units: 958314
value: -0.04229004000001
type: LocalParameter

123959
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

000616
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species: metaid M 318
type: SpeciesReference

035649
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

032082
units: 958314
value: 0.08172138000001
type: LocalParameter

106008
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

984949
stoichiometry: 1.0
species: metaid M 397
type: SpeciesReference

metaid R NIT2 2
name: Probable hydrolase NIT2
is: http://identifiers.org/ec-code/3.5.-.-
fast: false
reversible: false
type: Reaction
notes: SUBSYSTEM: Cyanoamino acid metabolism
modifier: 049220
kinetic law: 049232
product: 049196
reactant: 049184
product: 049208
is: SBO:0000176

metaid E 47
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constant: false
is: Q00764
initial amount: NaN
is: SBO:0000014
initial concentration: NaN
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type: Species
is: S000000330
boundary condition: false
in compartment: metaid C 2
notes: SHORT NAME: TPS1
is: sce00500

053878
stoichiometry: 1.0
species: metaid M 744
type: SpeciesReference

metaid E 675
type: Species
boundary condition: false
initial amount: NaN
initial concentration: NaN
notes: SHORT NAME: POS5
name: YPL188W
has only substance units: false
constant: false
in compartment: metaid C 2
is: S000006109
is: SBO:0000014
is: Q06892

127516
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid E 46
initial amount: NaN
notes: SHORT NAME: GRS1
type: Species
is: S000000325
has only substance units: false
initial concentration: NaN
is: sce00970
in compartment: metaid C 2
is: sce00260
boundary condition: false
is: P38088
constant: false
is: SBO:0000014
name: YBR121C

020101
units: 958314
value: 0.0
type: LocalParameter

126844
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid R THI80 1
product: 079619
is: http://identifiers.org/ec-code/2.7.6.2
kinetic law: 079643
reactant: 079595
is: SBO:0000176
product: 079607
modifier: 079631
name: Thiamine pyrophosphokinase
reversible: false
type: Reaction
notes: SUBSYSTEM: Thiamine (vitamin B1) metabolism
reactant: 079583
fast: false

129635
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R NIT2 3
kinetic law: 049340
type: Reaction
notes: SUBSYSTEM: Cyanoamino acid metabolism
product: 049304
product: 049316
is: http://identifiers.org/ec-code/3.5.-.-
fast: false
reversible: false
is: SBO:0000176
reactant: 049292
name: Probable hydrolase NIT2
modifier: 049328

010838
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

094204
units: 958314
value: 0.0
type: LocalParameter

047255
stoichiometry: 1.0
species: metaid M 796
type: SpeciesReference

133863
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

078959
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

974951
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

064009
units: 958314
value: 0.05016960000002
type: LocalParameter

metaid E 676
initial concentration: NaN
type: Species
name: YPL212C
initial amount: NaN
notes: SHORT NAME: PUS1
is: Q12211
is: S000006133
constant: false
has only substance units: false
is: SBO:0000014
boundary condition: false
in compartment: metaid C 2

979369
stoichiometry: 1.0
species: metaid M 797
type: SpeciesReference

003421
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

077683
units: 958314
value: 0.0
type: LocalParameter

033189
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R NAxtO
kinetic law: 139404
product: 139392
reactant: 139380
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of sodium
type: Reaction

metaid R PDE2 2
notes: SUBSYSTEM: Purine metabolism
modifier: 053517
name: 3',5'-cyclic-nucleotide phosphodiesterase 2
kinetic law: 053529
fast: false
is: http://identifiers.org/ec-code/3.1.4.17
product: 053505
type: Reaction
is: SBO:0000176
reactant: 053493
reversible: false

108917
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

084089
stoichiometry: 1.0
species: metaid M 693
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073851
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

983287
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

959227
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

967604
stoichiometry: 1.0
species: metaid M 733
type: SpeciesReference

metaid M 532
is: SBO:0000299
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: metaid C 2
name: inositol-mannose-P-inositol-P-D-ceramide
type: Species

metaid E 673
is: sce00970
boundary condition: false
initial amount: NaN
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constant: false
is: SBO:0000014
is: sce00290
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notes: SHORT NAME: CDC60
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name: YPL160W
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type: Species
initial concentration: NaN

048590
units: 958314
value: 0.0
type: LocalParameter

111396
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

065156
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

973898
stoichiometry: 1.0
species: metaid M 627
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061855
units: 958314
value: 0.0
type: LocalParameter

131827
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

141006
stoichiometry: 1.0
species: metaid M 1094
type: SpeciesReference

metaid E 124
is: sce00400
type: Species
in compartment: metaid C 2
has only substance units: false
initial concentration: NaN
initial amount: NaN
is: SBO:0000014
is: S000002442
is: P14843
constant: false
name: YDR035W
notes: SHORT NAME: ARO3
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metaid E 49
initial amount: NaN
is: SBO:0000014
has only substance units: false
is: S000000349
is: sce00350
is: sce00071
is: sce00010
type: Species
name: YBR145W
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initial concentration: NaN
notes: SHORT NAME: ADH5
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constant: false
boundary condition: false

019463
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

118571
stoichiometry: 1.0
species: metaid M 262
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106381
units: 958314
value: 0.0
type: LocalParameter

105042
stoichiometry: 1.0
species: metaid M 201
type: SpeciesReference

metaid R PDE2 1
name: 3',5'-cyclic-nucleotide phosphodiesterase 2
modifier: 053421
notes: SUBSYSTEM: Purine metabolism
kinetic law: 053433
product: 053409
fast: false
reactant: 053397
is: http://identifiers.org/ec-code/3.1.4.17
reversible: false
type: Reaction
is: SBO:0000176

metaid R FAA2 2
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kinetic law: 996104
reactant: 996044
notes: SUBSYSTEM: Fatty acid biosynthesis
type: Reaction
product: 996080
is: http://identifiers.org/ec-code/6.2.1.3
reversible: false
is: SBO:0000176
reactant: 996019
product: 996068
product: 996056
reactant: 996032
name: Long-chain-fatty-acid--CoA ligase 2
fast: false

128369
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

120960
stoichiometry: 1.0
species: metaid M 988
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969136
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

133598
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

963991
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

007324
units: 958314
value: 0.0
type: LocalParameter

metaid M 533
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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: metaid C 2
name: inositol-mannose-P-inositol-P-P-ceramide
type: Species

114645
stoichiometry: 1.0
species: metaid M 610
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metaid E 674
notes: SHORT NAME: COX10
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is: P21592
initial amount: NaN
type: Species
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name: YPL172C
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boundary condition: false
has only substance units: false
initial concentration: NaN
constant: false
in compartment: metaid C 2
is: sce00860

016449
units: 958314
value: 0.0
type: LocalParameter

091471
stoichiometry: 1.0
species: metaid M 979
type: SpeciesReference

111517
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 48
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boundary condition: false
notes: SHORT NAME: AGP2
is: P38090
type: Species
name: YBR132C
in compartment: metaid C 2
initial concentration: NaN
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constant: false
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metaid E 125
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has only substance units: false
is: S000002444
initial amount: NaN
boundary condition: false
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is: P15180
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notes: SHORT NAME: KRS1
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initial concentration: NaN
name: YDR037W
type: Species
is: sce00970

054492
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R PDE2 4
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product: 053698
kinetic law: 053722
reversible: false
reactant: 053686
notes: SUBSYSTEM: Purine metabolism
name: 3',5'-cyclic-nucleotide phosphodiesterase 2
is: http://identifiers.org/ec-code/3.1.4.17
fast: false
type: Reaction
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metaid R FAA2 1
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kinetic law: 995959
product: 995923
product: 995935
name: Long-chain-fatty-acid--CoA ligase 2
reactant: 995887
notes: SUBSYSTEM: Fatty acid biosynthesis
modifier: 995947
type: Reaction
product: 995911
is: http://identifiers.org/ec-code/6.2.1.3
fast: false
is: SBO:0000176
reactant: 995899
reactant: 995875

965336
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species: metaid M 601
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063481
units: 958314
value: 1000.0
name: UPPER_BOUND
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015182
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species: metaid M 579
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100863
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species: metaid M 321
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002937
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species: metaid M 507
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metaid M 530
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is: SBO:0000299
constant: false
initial amount: NaN
boundary condition: false
initial concentration: NaN
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name: 1-(indol-3-yl)glycerol 3-phosphate
type: Species
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098685
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species: metaid M 392
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103547
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

metaid E 671
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initial amount: NaN
constant: false
in compartment: metaid C 2
has only substance units: false
is: SBO:0000014
initial concentration: NaN
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005557
units: 958314
value: 0.16611074999992
type: LocalParameter

metaid E 122
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is: P48015
is: SBO:0000014
in compartment: metaid C 2
boundary condition: false
initial concentration: NaN
constant: false
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initial amount: NaN
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type: Species
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104910
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value: 0.0
type: LocalParameter

128261
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value: 0.0
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type: LocalParameter

075318
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species: metaid M 465
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042376
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R PDE2 3
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reactant: 053590
reversible: false
is: http://identifiers.org/ec-code/3.1.4.17
type: Reaction
is: SBO:0000176
kinetic law: 053626
product: 053602
fast: false
notes: SUBSYSTEM: Purine metabolism
modifier: 053614

043890
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R DINxtO
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product: 135165
reactant: 135153
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Excretion of deoxyinosine
type: Reaction

043963
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species: metaid M 742
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094733
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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078839
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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069676
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species: metaid M 417
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025495
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R U27
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reactant: 097373
reversible: false
is: http://identifiers.org/ec-code/3.1.3.5
notes: SUBSYSTEM: Salvage pathways
product: 097385
fast: false
is: SBO:0000176
name: 5'-nucleotidase
product: 097397
kinetic law: 097409

057528
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value: 0.0
type: LocalParameter

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type: Species
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initial amount: NaN
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initial concentration: NaN
is: SBO:0000014
notes: SHORT NAME: PPT2
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079499
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species: metaid M 877
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initial concentration: NaN
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type: Species
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metaid E 123
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is: SBO:0000014
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constant: false
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type: Species
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initial concentration: NaN

001278
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value: -1000.0
name: LOWER_BOUND
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099938
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species: metaid M 92
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101512
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species: metaid M 22
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003215
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species: metaid M 253
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metaid M 523
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initial amount: NaN
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type: Species
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metaid R ADE17 1
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type: Reaction
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modifier: 961156
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reactant: 961107
kinetic law: 961168
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product: 961144
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057216
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species: metaid M 636
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017850
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species: metaid M 221
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metaid R PDX3 2
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product: 054046
reactant: 054010
modifier: 054058
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notes: SUBSYSTEM: Pyridoxine (vitamin B6) metabolism
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is: http://identifiers.org/ec-code/1.4.3.5

130080
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species: metaid M 1096
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metaid R ECM31
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is: SBO:0000176
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metaid E 127
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metaid R PIMExtO
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product: 140246
reactant: 140233
notes: SUBSYSTEM: Exchange reactions
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reversible: false
name: Excretion of pimelic acid
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057540
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975095
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species: metaid M 130
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106658
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016221
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106213
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061000
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118704
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050787
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reactant: 107645
reactant: 107633

046833
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119197
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species: metaid M 230
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064216
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985300
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982709
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metaid E 63
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062096
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product: 054300
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095239
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notes: SUBSYSTEM: Pyridoxine (vitamin B6) metabolism
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metaid E 128
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015761
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species: metaid M 575
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metaid R ADE17 2
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metaid R PDX3 5
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product: 054420
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product: 054408
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140958
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016113
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129755
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072333
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value: 0.13452855000002
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metaid R ACxtI
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reversible: false
name: Uptake of acetate
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is: SBO:0000299
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species: metaid M 495
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species: metaid M 606
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035927
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species: metaid M 46
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in compartment: metaid C 2
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species: metaid M 606
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value: 1000.0
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072635
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species: metaid M 687
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initial concentration: NaN
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016341
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value: 0.69532542867807
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species: metaid M 333
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984396
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species: metaid M 713
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055022
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144131
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metaid R FAS2 6 2
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name: LOWER_BOUND
type: LocalParameter

050678
stoichiometry: 1.0
species: metaid M 692
type: SpeciesReference

metaid M 414
is: CHEBI:18077
constant: false
name: dTTP
initial concentration: NaN
initial amount: NaN
type: Species
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has only substance units: false
boundary condition: false
is: SBO:0000299

977097
units: 958314
value: 0.0
type: LocalParameter

metaid E 236
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constant: false
initial amount: NaN
notes: SHORT NAME: PNC1
is: S000003005
is: sce00760
has only substance units: false
boundary condition: false
is: SBO:0000014
is: P53184
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type: Species
initial concentration: NaN

966298
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

119041
units: 958314
value: 0.0
type: LocalParameter

101403
units: 958314
value: 0.0
type: LocalParameter

065264
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

102464
stoichiometry: 1.0
species: metaid M 880
type: SpeciesReference

003324
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

metaid R U181
name: Transport of deoxyguanosine, extracellular
type: Reaction
reactant: 091855
fast: false
product: 091867
kinetic law: 091879
reactant: 091843
is: SBO:0000185
notes: SUBSYSTEM: Transport, extracellular
reversible: false

118812
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

000171
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

967799
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

061156
stoichiometry: 1.0
species: metaid M 214
type: SpeciesReference

115138
stoichiometry: 1.0
species: metaid M 501
type: SpeciesReference

125187
stoichiometry: 1.0
species: metaid M 1038
type: SpeciesReference

metaid E 235
notes: SHORT NAME: TRP5
is: P00931
has only substance units: false
constant: false
initial concentration: NaN
initial amount: NaN
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name: YGL026C
is: S000002994
is: SBO:0000014
boundary condition: false
type: Species
in compartment: metaid C 2

086814
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

118102
units: 958314
value: 0.0
type: LocalParameter

097914
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 413
name: dTMP
in compartment: metaid C 2
is: CHEBI:17013
boundary condition: false
constant: false
is: SBO:0000299
type: Species
has only substance units: false
initial amount: NaN
initial concentration: NaN

973602
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

999545
stoichiometry: 1.0
species: metaid M 806
type: SpeciesReference

121282
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

987044
stoichiometry: 1.0
species: metaid M 771
type: SpeciesReference

metaid M 416
initial amount: NaN
type: Species
initial concentration: NaN
name: thymidine
is: SBO:0000299
has only substance units: false
boundary condition: false
is: CHEBI:17748
constant: false
in compartment: metaid C 3

metaid R YDL100C
kinetic law: 113293
notes: SUBSYSTEM: Folate metabolism
product: 113257
name: ATPase GET3
reversible: false
fast: false
reactant: 113245
product: 113269
modifier: 113281
is: SBO:0000176
type: Reaction
is: http://identifiers.org/ec-code/3.6.3.16

969839
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

129863
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

070802
stoichiometry: 1.0
species: metaid M 516
type: SpeciesReference

132961
stoichiometry: 1.0
species: metaid M 260
type: SpeciesReference

034116
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

962053
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

086670
units: 958314
value: 0.0
type: LocalParameter

090822
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

001963
units: 958314
value: 0.0
type: LocalParameter

123971
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

111420
stoichiometry: 1.0
species: metaid M 526
type: SpeciesReference

134610
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

043444
stoichiometry: 3.0
species: metaid M 693
type: SpeciesReference

124682
stoichiometry: 1.0
species: metaid M 1032
type: SpeciesReference

078731
units: 958314
value: 0.0
type: LocalParameter

metaid E 238
is: SBO:0000014
initial concentration: NaN
boundary condition: false
is: P21147
in compartment: metaid C 2
notes: SHORT NAME: OLE1
type: Species
is: S000003023
constant: false
is: sce01040
initial amount: NaN
name: YGL055W
has only substance units: false

057962
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 561
is: sce00290
is: sce00620
name: YNL104C
is: SBO:0000014
initial concentration: NaN
initial amount: NaN
is: S000005048
notes: SHORT NAME: LEU4
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is: P06208
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boundary condition: false
constant: false
type: Species

metaid M 415
type: Species
initial concentration: NaN
name: dTTP
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in compartment: metaid C 3
is: SBO:0000299
is: CHEBI:18077
constant: false
boundary condition: false
initial amount: NaN

metaid R URA2 1
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notes: SUBSYSTEM: Pyrimidine metabolism
name: Aspartate carbamoyltransferase
is: SBO:0000176
type: Reaction
fast: false
product: 107548
reactant: 107512
product: 107536
kinetic law: 107572
modifier: 107560
reactant: 107524
is: http://identifiers.org/ec-code/2.1.3.2

094493
stoichiometry: 1.0
species: metaid M 857
type: SpeciesReference

028545
stoichiometry: 1.0
species: metaid M 245
type: SpeciesReference

metaid R U103
name: Purine-nucleoside phosphorylase
reversible: true
type: Reaction
fast: false
reactant: 084743
is: http://identifiers.org/ec-code/2.4.2.1
product: 084755
reactant: 084731
product: 084767
kinetic law: 084779
notes: SUBSYSTEM: NAD biosynthesis
is: SBO:0000176

036444
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

073297
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

998714
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 237
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name: YGL040C
is: S000003008
initial concentration: NaN
has only substance units: false
is: SBO:0000014
boundary condition: false
is: sce00860
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constant: false
initial amount: NaN
notes: SHORT NAME: HEM2

metaid R PDX3 1
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kinetic law: 053950
product: 053926
notes: SUBSYSTEM: Pyridoxine (vitamin B6) metabolism
product: 053914
name: Pyridoxamine 5'-phosphate oxidase
type: Reaction
reactant: 053890
product: 053902
reactant: 053878
fast: false
reversible: false
is: SBO:0000176
is: http://identifiers.org/ec-code/1.4.3.5

metaid E 560
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constant: false
initial concentration: NaN
type: Species
name: YNL073W
notes: SHORT NAME: MSK1
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is: sce00300
is: SBO:0000014
initial amount: NaN
is: S000005017
is: P32048
has only substance units: false

metaid R FUI1 1
name: Uridine permease
notes: SUBSYSTEM: Transport, extracellular
type: Reaction
fast: false
reactant: 009382
is: SBO:0000185
modifier: 009418
product: 009406
reversible: false
kinetic law: 009430
reactant: 009394

963895
units: 958314
value: 0.0
type: LocalParameter

metaid E 550
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constant: false
is: sce00251
is: SBO:0000014
in compartment: metaid C 2
is: sce00252
has only substance units: false
is: Q03557
notes: SHORT NAME: HER2
is: S000004907
initial amount: NaN
boundary condition: false
name: YMR293C
initial concentration: NaN

085718
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid E 243
name: YGL148W
is: P28777
initial concentration: NaN
initial amount: NaN
type: Species
is: S000003116
has only substance units: false
in compartment: metaid C 2
boundary condition: false
notes: SHORT NAME: ARO2
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constant: false
is: sce00400

032552
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

977001
stoichiometry: 1.0
species: metaid M 307
type: SpeciesReference

116381
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

095179
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

133430
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

136848
stoichiometry: 1.0
species: metaid M 468
type: SpeciesReference

037191
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

098781
stoichiometry: 1.0
species: metaid M 22
type: SpeciesReference

079330
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

064663
stoichiometry: 1.0
species: metaid M 253
type: SpeciesReference

989804
stoichiometry: 1.0
species: metaid M 644
type: SpeciesReference

057649
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

094637
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 551
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type: Species
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is: SBO:0000014
notes: SHORT NAME: LCB1
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in compartment: metaid C 2
name: YMR296C
boundary condition: false
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initial amount: NaN
initial concentration: NaN
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050028
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid M 410
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is: SBO:0000299
name: dolichyl phosphate D-mannose
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constant: false
initial concentration: NaN
boundary condition: false
type: Species
has only substance units: false
initial amount: NaN

metaid E 244
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initial amount: NaN
type: Species
has only substance units: false
in compartment: metaid C 2
initial concentration: NaN
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is: SBO:0000014
constant: false
is: P53099
notes: SHORT NAME: TPN1
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005677
stoichiometry: 1.0
species: metaid M 437
type: SpeciesReference

035361
stoichiometry: 1.0
species: metaid M 649
type: SpeciesReference

981886
stoichiometry: 1.0
species: metaid M 298
type: SpeciesReference

993320
stoichiometry: 1.0
species: metaid M 426
type: SpeciesReference

099360
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

075415
stoichiometry: 1.0
species: metaid M 475
type: SpeciesReference

080547
stoichiometry: 1.0
species: metaid M 356
type: SpeciesReference

049027
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

035216
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

117438
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species: metaid M 84
type: SpeciesReference

084076
stoichiometry: 1.0
species: metaid M 318
type: SpeciesReference

metaid M 411
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constant: false
name: dolichyl phosphate
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notes: FORMULA: C20H37O4P(C5H8)n
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has only substance units: false
is: C00110
initial concentration: NaN
in compartment: metaid C 2
boundary condition: false

111275
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 552
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notes: SHORT NAME: ADE4
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is: S000004915
is: sce00230
initial amount: NaN
is: P04046
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boundary condition: false
constant: false
is: SBO:0000014
name: YMR300C
type: Species
initial concentration: NaN

126291
stoichiometry: 1.0
species: metaid M 1051
type: SpeciesReference

metaid R FUI1 3
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notes: SUBSYSTEM: Transport, extracellular
reactant: 009599
product: 009623
is: SBO:0000185
kinetic law: 009647
reactant: 009611
modifier: 009635
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type: Reaction

metaid R U15
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reactant: 088802
kinetic law: 088838
notes: SUBSYSTEM: Pyrimidine metabolism
reactant: 088790
name: Thymidine (deoxyuridine) kinase
product: 088814
is: http://identifiers.org/ec-code/2.7.1.21
reversible: false
is: SBO:0000176
fast: false

metaid E 245
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constant: false
initial amount: NaN
is: S000003170
initial concentration: NaN
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has only substance units: false
name: YGL202W
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is: P53090
type: Species

061228
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

122212
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

118692
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

111880
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

054372
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value: 0.0
type: LocalParameter

068557
units: 958314
value: 0.0
type: LocalParameter

050245
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

021931
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

026566
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

050895
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species: metaid M 138
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969016
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

968859
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species: metaid M 795
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962489
stoichiometry: 1.0
species: metaid M 432
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metaid M 412
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is: SBO:0000299
constant: false
is: CHEBI:18075
type: Species
initial concentration: NaN
boundary condition: false
initial amount: NaN
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114524
stoichiometry: 1.0
species: metaid M 515
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metaid E 553
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constant: false
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is: SBO:0000014
notes: SHORT NAME: ADH2
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type: Species
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initial amount: NaN
has only substance units: false
is: sce00010
initial concentration: NaN
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is: sce00350

metaid R FUI1 2
kinetic law: 009538
modifier: 009526
type: Reaction
reactant: 009502
name: Uridine permease
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reversible: false
reactant: 009490
product: 009514
fast: false
is: SBO:0000185

048494
stoichiometry: 1.0
species: metaid M 693
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metaid E 246
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is: P13711
is: sce00592
is: sce01040
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notes: SHORT NAME: POX1
initial concentration: NaN
is: sce00071
boundary condition: false
type: Species
is: SBO:0000014
constant: false
name: YGL205W
initial amount: NaN

metaid R U182
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type: Reaction
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product: 091963
is: SBO:0000185
kinetic law: 091975
reactant: 091951
notes: SUBSYSTEM: Transport, extracellular
reactant: 091939
fast: false

080693
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species: metaid M 267
type: SpeciesReference

033466
units: 958314
value: 0.06689280000001
type: LocalParameter

106995
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R ZYMSTxtI
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product: 131791
reactant: 131779
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of zymosterol
type: Reaction

039850
stoichiometry: 1.0
species: metaid M 634
type: SpeciesReference

012595
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

007040
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species: metaid M 893
type: SpeciesReference

metaid E 667
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in compartment: metaid C 2
constant: false
has only substance units: false
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is: sce00970
is: P15179
notes: SHORT NAME: MSD1
initial concentration: NaN
type: Species
is: sce00252
initial amount: NaN

077561
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

123815
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 554
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type: Species
constant: false
is: SBO:0000014
is: Q04952
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initial concentration: NaN
initial amount: NaN
has only substance units: false
boundary condition: false
notes: SHORT NAME: FKS3
is: sce00500

961568
stoichiometry: 1.0
species: metaid M 448
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979249
stoichiometry: 1.0
species: metaid M 81
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143443
stoichiometry: 0.17152
species: metaid M 588
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058010
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species: metaid M 501
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metaid R AUS1 6
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notes: SUBSYSTEM: Transport, extracellular
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type: Reaction
modifier: 972725
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kinetic law: 972737
product: 972713
reactant: 972701

129539
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

133346
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

053734
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

102319
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species: metaid M 624
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metaid E 668
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initial amount: NaN
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in compartment: metaid C 2
initial concentration: NaN
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has only substance units: false
notes: SHORT NAME: GDE1

123755
stoichiometry: 1.0
species: metaid M 1021
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139272
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 555
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is: SBO:0000014
name: YMR313C
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boundary condition: false
in compartment: metaid C 2
notes: SHORT NAME: TGL3
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metaid R FUN63
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type: Reaction
notes: SUBSYSTEM: Purine metabolism
reactant: 009912
reversible: false
is: SBO:0000176
fast: false
modifier: 009948
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kinetic law: 009960
product: 009936
product: 009924

137490
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

087900
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

082130
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species: metaid M 578
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000736
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species: metaid M 800
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113727
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species: metaid M 18
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061952
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid R AUS1 7
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product: 972809
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kinetic law: 972833
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140801
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid R YDR531W
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product: 113751
product: 113763
is: http://identifiers.org/ec-code/2.7.1.33
kinetic law: 113787
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modifier: 113775
reactant: 113727
reactant: 113739
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name: Pantothenate kinase

094301
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species: metaid M 450
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980091
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 669
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has only substance units: false
is: sce00330
boundary condition: false
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initial concentration: NaN
type: Species
is: S000006032
initial amount: NaN
is: SBO:0000014
notes: SHORT NAME: CAR1

metaid E 241
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constant: false
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initial amount: NaN
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metaid R DTxtI
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product: 124357
reactant: 124345
notes: SUBSYSTEM: Exchange reactions
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fast: false
reversible: false
name: Uptake of thymidine
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034999
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

960488
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

060602
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species: metaid M 378
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043661
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid R ZYMSTxtO
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product: 142863
reactant: 142851
notes: SUBSYSTEM: Exchange reactions
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fast: false
reversible: false
name: Excretion of zymosterol
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metaid E 556
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initial concentration: NaN
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notes: SHORT NAME: DIA1
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metaid R THI20 2
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kinetic law: 078923
reactant: 078875
is: http://identifiers.org/ec-code/2.7.4.7
modifier: 078911
product: 078887
reactant: 078863
type: Reaction
name: Phosphomethylpyrimidine kinase THI20
product: 078899
reversible: false
notes: SUBSYSTEM: Thiamine (vitamin B1) metabolism

034260
stoichiometry: 1.0
species: metaid M 42
type: SpeciesReference

096552
stoichiometry: 1.0
species: metaid M 855
type: SpeciesReference

110707
stoichiometry: 1.0
species: metaid M 628
type: SpeciesReference

958816
stoichiometry: 1.0
species: metaid M 698
type: SpeciesReference

metaid R THYxtI
kinetic law: 130780
product: 130768
reactant: 130756
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of thymine
type: Reaction

metaid R FAS2 5 1
type: Reaction
name: 3-oxoacyl-[acyl-carrier-protein] synthase
kinetic law: 001662
modifier: 001650
reactant: 001585
product: 001624
product: 001637
reactant: 001598
product: 001611
fast: false
notes: SUBSYSTEM: Cytosolic fatty acid synthesis
reversible: false
is: http://identifiers.org/ec-code/2.3.1.41
is: SBO:0000176

metaid E 240
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initial amount: NaN
boundary condition: false
initial concentration: NaN
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notes: SHORT NAME: PUS2

133646
stoichiometry: 1.0
species: metaid M 1007
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008419
units: 958314
value: 0.0
type: LocalParameter

metaid R AUS1 8
modifier: 972917
fast: false
is: SBO:0000185
notes: SUBSYSTEM: Transport, extracellular
type: Reaction
name: ATP-dependent permease AUS1
product: 972905
reversible: true
kinetic law: 972929
reactant: 972893

metaid E 557
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initial concentration: NaN
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is: S000004954
is: P53982
notes: SHORT NAME: IDP3
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069184
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species: metaid M 230
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metaid E 242
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notes: SHORT NAME: MET13
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type: Species
is: P53128
is: sce00680
is: SBO:0000014
constant: false
boundary condition: false
is: S000003093
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metaid R THI20 1
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reactant: 078743
kinetic law: 078803
reversible: false
notes: SUBSYSTEM: Thiamine (vitamin B1) metabolism
modifier: 078791
type: Reaction
reactant: 078755
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product: 078779
is: SBO:0000176
name: Phosphomethylpyrimidine kinase THI20
product: 078767

078513
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017965
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value: 0.0
type: LocalParameter

027827
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name: OBJECTIVE_COEFFICIENT
type: LocalParameter

047354
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species: metaid M 624
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962271
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species: metaid M 575
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019511
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species: metaid M 391
type: SpeciesReference

984805
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value: 1000.0
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type: LocalParameter

082853
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species: metaid M 692
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972785
units: 958314
value: 0.0
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metaid R LACxtI
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product: 127144
reactant: 127132
notes: SUBSYSTEM: Exchange reactions
is: SBO:0000185
fast: false
reversible: false
name: Uptake of (R)-lactate
type: Reaction

969947
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value: 0.0
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032094
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species: metaid M 121
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112204
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

098070
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species: metaid M 972
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035637
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

metaid R U125
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product: 086694
reactant: 086682
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Transport of 2-acetolactate, mitochondrial
type: Reaction

metaid R OAR1 3
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is: http://identifiers.org/ec-code/1.-.-.-
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
reversible: true
modifier: 050462
name: Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase
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reactant: 050426
kinetic law: 050474
product: 050438
reactant: 050414
fast: false

metaid R AUS1 2
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name: ATP-dependent permease AUS1
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reactant: 972311
type: Reaction
fast: false
kinetic law: 972348
reversible: true
modifier: 972336
product: 972324

139164
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

077670
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

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is: S000005982
initial concentration: NaN
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is: sce00650
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is: P54115
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007311
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name: OBJECTIVE_COEFFICIENT
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962379
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species: metaid M 195
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metaid E 558
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boundary condition: false
has only substance units: false
initial amount: NaN
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initial concentration: NaN
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constant: false
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metaid E 59
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is: SBO:0000014
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initial amount: NaN
initial concentration: NaN
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987260
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value: 0.3201861
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126832
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

991128
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value: 0.0
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type: LocalParameter

129647
units: 958314
value: 0.0
type: LocalParameter

metaid E 130
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has only substance units: false
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is: SBO:0000014
in compartment: metaid C 2
boundary condition: false
initial amount: NaN
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047243
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species: metaid M 623
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027611
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

081793
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species: metaid M 31
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133875
units: 958314
value: 0.0
type: LocalParameter

metaid R U119
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product: 086188
reactant: 086175
notes: SUBSYSTEM: Transport, mitochondrial
is: SBO:0000185
fast: false
reversible: true
name: Transport of 4-methyl-2-oxopentanoate, mitochondrial
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963008
stoichiometry: 1.0
species: metaid M 689
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metaid R OAR1 4
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modifier: 050582
product: 050570
is: SBO:0000176
kinetic law: 050594
reactant: 050534
is: http://identifiers.org/ec-code/1.-.-.-
name: Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase
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type: Reaction
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
product: 050558
reversible: true

127504
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

020113
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species: metaid M 974
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metaid R AUS1 3
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modifier: 972434
fast: false
product: 972422
reactant: 972410
notes: SUBSYSTEM: Transport, extracellular
name: ATP-dependent permease AUS1
type: Reaction
kinetic law: 972447
is: SBO:0000185

006509
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

061843
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid E 664
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constant: false
boundary condition: false
is: Q02896
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name: YPL087W
initial concentration: NaN
is: SBO:0000014
initial amount: NaN
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003433
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value: 1000.0
name: UPPER_BOUND
type: LocalParameter

001121
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species: metaid M 318
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024678
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

979357
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species: metaid M 698
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metaid E 131
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boundary condition: false
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in compartment: metaid C 2
is: SBO:0000014
has only substance units: false
initial concentration: NaN
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016003
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species: metaid M 671
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has only substance units: false
is: SBO:0000014
constant: false
boundary condition: false
initial amount: NaN
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notes: SHORT NAME: KTR4

metaid E 559
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is: sce00620
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initial concentration: NaN
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is: SBO:0000014
type: Species
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notes: SHORT NAME: LAT1
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078947
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

095456
units: 958314
value: 0.0
type: LocalParameter

090930
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

021377
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

076390
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species: metaid M 839
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metaid E 57
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constant: false
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notes: SHORT NAME: PGI1
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is: S000000400

085020
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

metaid R AUS1 4
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is: SBO:0000185
notes: SUBSYSTEM: Transport, extracellular
modifier: 972531
type: Reaction
name: ATP-dependent permease AUS1
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reactant: 972507
kinetic law: 972543
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metaid R OAR1 1
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product: 050209
is: http://identifiers.org/ec-code/1.-.-.-
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
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product: 050197
fast: false
kinetic law: 050233
reactant: 050173
type: Reaction
reactant: 050185
reversible: true

109651
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value: 0.0
type: LocalParameter

139815
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species: metaid M 1080
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974011
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species: metaid M 569
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108808
stoichiometry: 1.0
species: metaid M 975
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053662
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

058856
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value: 0.0
name: OBJECTIVE_COEFFICIENT
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metaid E 665
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initial concentration: NaN
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in compartment: metaid C 2
name: YPL091W
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is: P41921
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notes: SHORT NAME: GLR1
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981730
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value: 0.0
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106550
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value: 0.08172138000001
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079775
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid E 132
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is: S000002479
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name: YDR072C
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initial amount: NaN
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115296
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value: -1000.0
name: LOWER_BOUND
type: LocalParameter

962162
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value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R AUS1 5
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reactant: 972604
kinetic law: 972640
notes: SUBSYSTEM: Transport, extracellular
name: ATP-dependent permease AUS1
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reversible: true
fast: false
product: 972616

metaid E 56
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boundary condition: false
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959626
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species: metaid M 262
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968747
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value: 0.0
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027936
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value: 0.0
type: LocalParameter

metaid R OAR1 2
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kinetic law: 050353
name: Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase
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reactant: 050293
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reactant: 050305
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notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
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reversible: true
type: Reaction

095384
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species: metaid M 501
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078622
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value: 0.0
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043553
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value: 0.01811686499989
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961410
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value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

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is: P48527
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in compartment: metaid C 2
is: SBO:0000014
initial amount: NaN
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initial concentration: NaN
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notes: SHORT NAME: MSY1
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082745
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species: metaid M 819
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971263
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species: metaid M 698
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initial amount: NaN

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value: 0.0
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species: metaid M 229
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968307
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species: metaid M 334
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value: -1000.0
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name: OBJECTIVE_COEFFICIENT
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015194
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species: metaid M 795
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100875
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species: metaid M 682
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metaid R OAR1 7
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reversible: true
modifier: 050943
kinetic law: 050955
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reactant: 050895
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notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
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name: Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase
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134730
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species: metaid M 965
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128273
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098673
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notes: SUBSYSTEM: Exchange reactions
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product: 051039
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111384
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

131839
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

122369
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid R AUS1 1
reversible: true
is: SBO:0000185
notes: SUBSYSTEM: Transport, extracellular
fast: false
kinetic law: 972251
type: Reaction
name: ATP-dependent permease AUS1
modifier: 972239
reactant: 972215
product: 972227

969124
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

133586
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

metaid R OAR1 6
kinetic law: 050835
notes: SUBSYSTEM: Mitochondrial type II fatty acid synthase
is: http://identifiers.org/ec-code/1.-.-.-
fast: false
is: SBO:0000176
product: 050811
reactant: 050775
reversible: true
name: Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase
reactant: 050787
type: Reaction
modifier: 050823
product: 050799

095021
stoichiometry: 1.0
species: metaid M 499
type: SpeciesReference

063589
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

118584
stoichiometry: 1.0
species: metaid M 302
type: SpeciesReference

metaid E 137
is: sce00300
notes: SHORT NAME: HOM2
type: Species
is: sce00260
initial concentration: NaN
is: S000002565
name: YDR158W
is: SBO:0000014
initial amount: NaN
is: P13663
in compartment: metaid C 2
has only substance units: false
constant: false
boundary condition: false

054480
units: 958314
value: 1000.0
name: UPPER_BOUND
type: LocalParameter

114633
stoichiometry: 1.0
species: metaid M 262
type: SpeciesReference

metaid M 521
type: Species
is: CHEBI:17368
constant: false
has only substance units: false
boundary condition: false
in compartment: metaid C 2
is: SBO:0000299
initial amount: NaN
initial concentration: NaN
name: hypoxanthine

metaid E 662
name: YPL057C
in compartment: metaid C 2
is: S000005978
initial concentration: NaN
notes: SHORT NAME: SUR1
is: SBO:0000014
boundary condition: false
has only substance units: false
type: Species
initial amount: NaN
is: P33300
constant: false

111529
units: 958314
value: 0.00525027749995
type: LocalParameter

metaid R U26
kinetic law: 097313
reactant: 097277
product: 097301
product: 097289
is: http://identifiers.org/ec-code/3.1.3.5
reversible: false
notes: SUBSYSTEM: Salvage pathways
is: SBO:0000176
fast: false
type: Reaction
name: 5'-nucleotidase

066108
stoichiometry: 1.0
species: metaid M 692
type: SpeciesReference

014169
units: 958314
value: 0.0
name: LOWER_BOUND
type: LocalParameter

088370
stoichiometry: 1.0
species: metaid M 224
type: SpeciesReference

124826
units: dimensionless
value: 0.0
name: OBJECTIVE_COEFFICIENT
type: LocalParameter

989707
stoichiometry: 1.0
species: metaid M 321
type: SpeciesReference

066330
stoichiometry: 1.0
species: metaid M 489
type: SpeciesReference

metaid M 874
boundary condition: false
in compartment: metaid C 1
type: Species
is: CHEBI:20506
initial concentration: NaN
has only substance units: false
initial amount: NaN
constant: false
is: SBO:0000299
name: tetrahydrofolate

metaid M 1058
is: SBO:0000299
constant: false
in compartment: metaid C 4
has only substance units: false
type: Species
boundary condition: true
name: L-isoleucine
is: CHEBI:17191
initial amount: NaN
initial concentration: NaN

metaid R HPT1 2
reversible: false
is: SBO:0000176
name: Hypoxanthine-guanine phosphoribosyltransferase
fast: false
notes: SUBSYSTEM: Salvage pathways
kinetic law: 023510
type: Reaction
product: 023485
is: http://identifiers.org/ec-code/2.4.2.8
product: 023473
reactant: 023449
reactant: 023461
modifier: 023498

960562
stoichiometry: 1.0
species: metaid M 461
type: SpeciesReference

011270
units: 958314
value: -1000.0
name: LOWER_BOUND
type: LocalParameter

123382
units: 958314
value: 0.0
name: UPPER_BOUND
type: LocalParameter

metaid R GAP1 1
reactant: 011006
reversible: true
is: SBO:0000185
type: Reaction
fast: false
modifier: 011030
kinetic law: 011042
product: 011018
name: General amino-acid permease GAP1
notes: SUBSYSTEM: Transport, extracellular