462491
constant: true
units: dimensionless
value: 1.5
name: AUSLP
type: Parameter

462483
constant: true
units: dimensionless
value: 0.1
name: O2A
type: Parameter

462437
constant: false
units: dimensionless
value: NaN
name: AUC
type: Parameter

462505
constant: true
units: dimensionless
value: 0.0
name: CRRFLX
type: Parameter

462467
constant: false
units: dimensionless
value: NaN
name: AUM
type: Parameter

462487
constant: true
units: dimensionless
value: 0.3
name: AUDMP
type: Parameter

462448
constant: false
units: dimensionless
value: 1.00132
name: AU6
type: Parameter

462430
constant: true
units: dimensionless
value: 97.0439
name: PO2ART
type: Parameter

462496
constant: true
units: dimensionless
value: 0.5
name: AUN1
type: Parameter

462444
constant: false
units: dimensionless
value: NaN
name: A1B
type: Parameter

462501
constant: true
units: dimensionless
value: 1.0
name: AUX
type: Parameter

462434
constant: true
units: dimensionless
value: 15.6376
name: PPA
type: Parameter

462477
constant: true
units: dimensionless
value: 1.5
name: AUL
type: Parameter

462440
constant: false
units: dimensionless
value: NaN
name: AUC2
type: Parameter

462463
constant: false
units: dimensionless
value: NaN
name: AUH
type: Parameter

462492
constant: true
units: dimensionless
value: 1.0
name: EXC
type: Parameter

462466
constant: false
units: dimensionless
value: NaN
name: AOM
type: Parameter

462452
constant: false
units: dimensionless
value: NaN
name: AUEX
type: Parameter

462456
constant: false
units: dimensionless
value: NaN
name: AU
type: Parameter

MODEL0911270005
parameter: 462479
parameter: 462489
rule: 462401
parameter: 462452
parameter: 462431
parameter: 462441
volume units: volume
notes: This a model from the article: Circulation: overall regulation. Guyton AC, Coleman TG, Granger HJ. Annu Rev Physiol 1972;34:13-46 4334846 , Abstract: This article is an experiment, one undertaken primarily because of the long-term belief of Dr. Victor Hall, Editor of the Annual Review of Physiology fo r many years, that physiology is, or at least should be, an analytical subject, and that a method not utilized to its fullest advantage for organizing review material is the systems analysis. Furthermore, one of the most likely areas in physiology for which a systems analysis could be of value would be in a discussion of circulatory regulation. Therefore, this article was undertaken directly at the request of the editors of the A ogy to attempt the welding togeth er of a systemsn annuaally Rsiesv ioewf coifr cPuhlaytsoiorlyregulation with a review of the current literature in this field. The systems analysis of circulatory regulation developed for this article is based on earlier, much less extensive analyses (Guyton and Coleman 1, 2); it i s illustrated in Figure 1. This analysis is comprised of 354 blocks, each of which represents one or more mathematical equations describing some physiological facet of circulatory function. In general, each of the functional blocks has been the subject of research investigation by one or many investigator s, but the analysis is based on cumulative knowledge of the circulation rather than simply on current literature. Therefore, the analysis presented here is not a review of the current literature but is a framework to show how the different regulations operate together in the overall system. Later in this review we will attempt to show some of the voids still present in our knowledge of circulatory regulation (which is perhaps the most important value of performing systems analyses), and we will discuss the current research that is attempting to fill these voids. A criticism that has often been made against systems analyses, and ver…
parameter: 462483
rule: 462422
rule: 462414
parameter: 462493
parameter: 462432
parameter: 462500
parameter: 462485
parameter: 462496
parameter: 462456
rule: 462405
parameter: 462435
parameter: 462445
area units: area
rule: 462424
parameter: 462477
curated: false
parameter: 462442
parameter: 462454
rule: 462398
rule: 462394
rule: 462418
rule: 462421
rule: 462411
parameter: 462467
rule: 462413
parameter: 462440
rule: 462403
rule: 462409
parameter: 462480
parameter: 462491
is described by: http://identifiers.org/pubmed/4334846
parameter: 462470
parameter: 462495
parameter: 462438
parameter: 462446
parameter: 462487
parameter: 462458
parameter: 462449
parameter: 462484
type: SBMLModel
parameter: 462497
parameter: 462488
name: Guyton1972_Autonomics
parameter: 462463
rule: 462417
rule: 462407
parameter: 462504
parameter: 462478
parameter: 462460
parameter: 462428
parameter: 462464
rule: 462426
parameter: 462501
rule: 462395
parameter: 462451
parameter: 462505
substance units: 573275
parameter: 462455
rule: 462397
parameter: 462430
rule: 462420
rule: 462410
time units: 577459
rule: 462402
parameter: 462492
parameter: 462471
parameter: 462481
parameter: 462444
parameter: 462468
parameter: 462499
parameter: 462459
length unit: 027038

462497
constant: true
units: dimensionless
value: 0.0
name: MDMP
type: Parameter

462431
constant: true
units: dimensionless
value: 2.0
name: PLA
type: Parameter

462435
constant: false
units: dimensionless
value: NaN
name: PA1
type: Parameter

462449
constant: false
units: dimensionless
value: NaN
name: AUN
type: Parameter

462462
constant: false
units: dimensionless
value: NaN
name: VVR
type: Parameter

462445
constant: false
units: dimensionless
value: NaN
name: AU6A
type: Parameter

462441
constant: false
units: dimensionless
value: NaN
name: AU6C
type: Parameter

462493
constant: true
units: dimensionless
value: 0.01
name: EXCML
type: Parameter

462481
constant: true
units: dimensionless
value: 1.0
name: AUS
type: Parameter

462485
constant: true
units: dimensionless
value: 1.0
name: AUM2
type: Parameter

462471
constant: true
units: dimensionless
value: 2.51
name: VV9
type: Parameter

462459
constant: false
units: dimensionless
value: 1.00007
name: AU1
type: Parameter

462455
constant: false
units: dimensionless
value: NaN
name: AUTTL1
type: Parameter

462507
constant: true
units: dimensionless
value: 0.0
name: EXE
type: Parameter

462479
constant: true
units: dimensionless
value: 0.0
name: AUY
type: Parameter

462503
constant: true
units: dimensionless
value: 0.01
name: O2CHMO
type: Parameter

462451
constant: false
units: dimensionless
value: NaN
name: AULP
type: Parameter

462480
constant: true
units: dimensionless
value: 0.55
name: AUV
type: Parameter

462442
constant: false
units: dimensionless
value: NaN
name: AUB
type: Parameter

462432
constant: true
units: dimensionless
value: 0.00852183
name: PRA
type: Parameter

462446
constant: true
units: dimensionless
value: -0.060024
name: AU4
type: Parameter

462489
constant: true
units: dimensionless
value: 0.4
name: AUMIN
type: Parameter

462464
constant: false
units: dimensionless
value: NaN
name: AUR
type: Parameter

462428
constant: true
units: dimensionless
value: 103.525
name: PA
type: Parameter

462438
constant: false
units: dimensionless
value: NaN
name: AUC3
type: Parameter

462468
constant: false
units: dimensionless
value: NaN
name: AVE
type: Parameter

462458
constant: false
units: dimensionless
value: NaN
name: DAU
type: Parameter

462470
constant: false
units: dimensionless
value: NaN
name: AUO
type: Parameter

462390
constant: true
units: litre
size: 1.0
spatial dimensions: 3.0
type: Compartment

462484
constant: true
units: dimensionless
value: 3.0
name: AUM1
type: Parameter

462454
constant: false
units: dimensionless
value: NaN
name: AUTTL
type: Parameter

462478
constant: true
units: dimensionless
value: 0.0
name: AULPM
type: Parameter

462488
constant: true
units: dimensionless
value: 5.0
name: AUMAX
type: Parameter

462499
constant: true
units: dimensionless
value: 0.16
name: BAROTC
type: Parameter

462504
constant: true
units: dimensionless
value: 0.3
name: AUC1
type: Parameter

462500
constant: true
units: dimensionless
value: 0.004
name: AUK
type: Parameter

462495
constant: true
units: dimensionless
value: 1.0
name: EXCXP
type: Parameter

462460
constant: false
units: dimensionless
value: NaN
name: AUT
type: Parameter