321965
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334480
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321603
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species: 880032
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890851
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product: 324677
reactant: 324665
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reversible: false
name: C_ccw8ass
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878112
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name: R_ccw10
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322109
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343304
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species: 878392
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897651
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modifier: 338188
product: 338176
fast: false
reversible: false
name: C_ccwtoE_ccw4
type: Reaction

003493
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319608
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species: 878892
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324857
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species: 879892
type: SpeciesReference

003162
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896631
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product: 336039
reactant: 336027
fast: false
reversible: false
name: Aconfchange_cw20
type: Reaction

336516
stoichiometry: 1.0
species: 882372
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005023
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name: C_cc
type: LocalParameter

887351
kinetic law: 318128
product: 318116
reactant: 318104
fast: false
reversible: false
name: R_cw11diss
type: Reaction

328908
stoichiometry: 1.0
species: 879952
type: SpeciesReference

898410
kinetic law: 339832
modifier: 339819
product: 339807
fast: false
reversible: false
name: C_cwtoE_cw27
type: Reaction

002829
value: 810000.0
name: k10_cw
type: LocalParameter

894911
kinetic law: 332933
product: 332921
reactant: 332909
fast: false
reversible: false
name: C_cw22toA0_cw
type: Reaction

002628
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name: kdissR_cc
type: LocalParameter

884752
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 3.51745986907997E-12
in compartment: 877675
name: E_cw42
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004072
value: 2.07E-9
name: k20_cw
type: LocalParameter

002772
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name: kdissR_cc
type: LocalParameter

004861
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type: LocalParameter

890051
kinetic law: 323028
product: 323016
reactant: 323004
fast: false
reversible: false
name: R_ccw33toC_ccw33
type: Reaction

002601
value: 0.9314
name: kdissR_cw
type: LocalParameter

003721
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name: kdissC_cc
type: LocalParameter

886392
kinetic law: 315528
modifier: 315515
product: 315503
reactant: 315491
fast: false
reversible: false
name: R_ccw24ass
type: Reaction

330960
stoichiometry: 1.0
species: 881032
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326522
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species: 880612
type: SpeciesReference

894991
kinetic law: 333078
product: 333066
reactant: 333054
fast: false
reversible: false
name: C_cw24toA0_cw
type: Reaction

886312
kinetic law: 315334
modifier: 315322
product: 315310
reactant: 315298
fast: false
reversible: false
name: R_ccw22ass
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333861
stoichiometry: 1.0
species: 881272
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345543
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species: 879132
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899210
kinetic law: 341407
modifier: 341395
modifier: 341383
product: 341371
reactant: 341359
fast: false
reversible: false
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326377
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species: 880552
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004315
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899170
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modifier: 341274
modifier: 341262
product: 341250
reactant: 341238
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reversible: false
name: Start_cwtoR_cw1
type: Reaction

898490
kinetic law: 339979
modifier: 339967
product: 339954
fast: false
reversible: false
name: C_cwtoE_cw29
type: Reaction

342640
stoichiometry: 1.0
species: 878172
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003724
value: 0.03338
name: kdissC_cw
type: LocalParameter

896571
kinetic law: 335943
product: 335931
reactant: 335919
fast: false
reversible: false
name: Aconfchange_ccw18
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324135
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species: 879592
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343897
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species: 884872
type: SpeciesReference

004648
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name: ks_cw
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002604
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name: kdissR_cc
type: LocalParameter

324917
stoichiometry: 1.0
species: 879952
type: SpeciesReference

886512
kinetic law: 315816
modifier: 315804
product: 315792
reactant: 315780
fast: false
reversible: false
name: R_ccw27ass
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003517
value: 0.1177
name: kassC_cc
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877932
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw6
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005431
value: 2.48
name: kstop_cc
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004120
value: 2.07E-9
name: k20_cw
type: LocalParameter

340532
stoichiometry: 1.0
species: 884552
type: SpeciesReference

002625
value: 0.9314
name: kdissR_cw
type: LocalParameter

003490
value: 0.1177
name: kassC_cw
type: LocalParameter

319011
stoichiometry: 1.0
species: 878612
type: SpeciesReference

339121
stoichiometry: 1.0
species: 883772
type: SpeciesReference

003403
value: 0.1177
name: kassC_cc
type: LocalParameter

343231
stoichiometry: 1.0
species: 884892
type: SpeciesReference

323841
stoichiometry: 1.0
species: 879472
type: SpeciesReference

002826
value: 0.6
name: R_cc
type: LocalParameter

003727
value: 0.03338
name: kdissC_cc
type: LocalParameter

889291
kinetic law: 321651
product: 321639
reactant: 321627
fast: false
reversible: false
name: R_ccw14toC_ccw14
type: Reaction

004291
value: 0.6
name: C_cw
type: LocalParameter

003400
value: 0.1177
name: kassC_cw
type: LocalParameter

323052
stoichiometry: 1.0
species: 880832
type: SpeciesReference

002982
value: 0.6
name: R_cc
type: LocalParameter

002622
value: 0.9314
name: kdissR_cc
type: LocalParameter

879572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_ccw2
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005380
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name: kstop_cw
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323486
stoichiometry: 1.0
species: 881072
type: SpeciesReference

002775
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name: kdissR_cw
type: LocalParameter

317704
stoichiometry: 1.0
species: 877912
type: SpeciesReference

335588
stoichiometry: 1.0
species: 881832
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334876
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species: 881472
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885412
kinetic law: 313156
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product: 313131
reactant: 313119
fast: false
reversible: false
name: R_cw0ass
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004126
value: 2.07E-9
name: k20_cc
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899870
kinetic law: 343402
modifier: 343390
modifier: 343378
product: 343366
reactant: 343354
fast: false
reversible: false
name: Start_ccwtoR_ccw18
type: Reaction

888611
kinetic law: 320420
product: 320408
reactant: 320396
fast: false
reversible: false
name: R_ccw42diss
type: Reaction

315056
stoichiometry: 1.0
species: 878472
type: SpeciesReference

895731
kinetic law: 334420
product: 334408
reactant: 334395
fast: false
reversible: false
name: C_ccw42toA0_ccw
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327978
stoichiometry: 1.0
species: 881212
type: SpeciesReference

003496
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name: kassC_cw
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003282
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name: R_cc
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338212
stoichiometry: 1.0
species: 883272
type: SpeciesReference

879612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
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name: C_ccw3
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893091
kinetic law: 329628
product: 329616
reactant: 329603
fast: false
reversible: false
name: C_ccw21diss
type: Reaction

004123
value: 0.6
name: C_cw
type: LocalParameter

334756
stoichiometry: 1.0
species: 881372
type: SpeciesReference

005020
value: 2.07E-9
name: k20_cc
type: LocalParameter

334696
stoichiometry: 1.0
species: 881372
type: SpeciesReference

344258
stoichiometry: 1.0
species: 884872
type: SpeciesReference

889971
kinetic law: 322883
product: 322871
reactant: 322859
fast: false
reversible: false
name: R_ccw31toC_ccw31
type: Reaction

324002
stoichiometry: 1.0
species: 879572
type: SpeciesReference

897671
kinetic law: 338274
modifier: 338261
product: 338248
fast: false
reversible: false
name: C_ccwtoE_ccw5
type: Reaction

888031
kinetic law: 319360
product: 319348
reactant: 319336
fast: false
reversible: false
name: R_cw28diss
type: Reaction

002562
value: 0.9314
name: kdissR_cc
type: LocalParameter

319934
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species: 879072
type: SpeciesReference

004537
value: 7.0
name: ks_cc
type: LocalParameter

336809
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species: 882532
type: SpeciesReference

002823
value: 810000.0
name: k10_cc
type: LocalParameter

332365
stoichiometry: 1.0
species: 880052
type: SpeciesReference

880772
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
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name: C_ccw32
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335967
stoichiometry: 1.0
species: 882072
type: SpeciesReference

893951
kinetic law: 331188
product: 331176
reactant: 331164
fast: false
reversible: false
name: C_cw43diss
type: Reaction

331357
stoichiometry: 1.0
species: 881292
type: SpeciesReference

004645
value: 7.0
name: ks_cc
type: LocalParameter

900830
kinetic law: 346305
modifier: 346293
modifier: 346281
product: 346269
reactant: 346257
fast: false
reversible: false
name: Start_ccwtoR_ccw42
type: Reaction

003910
value: 2.07E-9
name: k20_cc
type: LocalParameter

897650
kinetic law: 338163
modifier: 338150
product: 338138
fast: false
reversible: false
name: C_cwtoE_cw4
type: Reaction

341853
stoichiometry: 1.0
species: 877932
type: SpeciesReference

318443
stoichiometry: 1.0
species: 878252
type: SpeciesReference

004312
value: 2.07E-9
name: k20_cw
type: LocalParameter

328195
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species: 879512
type: SpeciesReference

329288
stoichiometry: 1.0
species: 880112
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004426
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name: ks_cw
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884532
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boundary condition: false
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initial concentration: NaN
initial amount: 8.55114003056288E-5
in compartment: 877675
name: E_ccw36
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898950
kinetic law: 340812
modifier: 340799
product: 340786
fast: false
reversible: false
name: C_ccwtoE_ccw40
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883712
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 2.16146975707808E-7
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name: E_cw16
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338102
stoichiometry: 1.0
species: 883212
type: SpeciesReference

003392
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name: kassC_cc
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335859
stoichiometry: 1.0
species: 882012
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331249
stoichiometry: 1.0
species: 881192
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899650
kinetic law: 342737
modifier: 342725
modifier: 342712
product: 342700
reactant: 342688
fast: false
reversible: false
name: Start_cwtoR_cw13
type: Reaction

333174
stoichiometry: 1.0
species: 881292
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344318
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species: 884892
type: SpeciesReference

004129
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name: C_cc
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341044
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species: 884832
type: SpeciesReference

332257
stoichiometry: 1.0
species: 879992
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329066
stoichiometry: 1.0
species: 879992
type: SpeciesReference

005371
value: 2.48
name: kstop_cc
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334984
stoichiometry: 1.0
species: 881532
type: SpeciesReference

002985
value: 810000.0
name: k10_cw
type: LocalParameter

884332
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 7.54214434512586E-4
in compartment: 877675
name: E_ccw31
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002340
value: 0.5341
name: kassR_cc
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895511
kinetic law: 334020
product: 334008
reactant: 333996
fast: false
reversible: false
name: C_cw37toA0_cw
type: Reaction

004294
value: 2.07E-9
name: k20_cc
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004756
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name: k20_cc
type: LocalParameter

340864
stoichiometry: 1.0
species: 884732
type: SpeciesReference

897670
kinetic law: 338236
modifier: 338224
product: 338212
fast: false
reversible: false
name: C_cwtoE_cw5
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340972
stoichiometry: 1.0
species: 884792
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335370
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species: 881712
type: SpeciesReference

004201
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318068
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species: 878112
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334540
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species: 881252
type: SpeciesReference

896291
kinetic law: 335430
product: 335418
reactant: 335406
fast: false
reversible: false
name: Aconfchange_ccw11
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005503
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name: sigmaphi
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892711
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product: 328920
reactant: 328908
fast: false
reversible: false
name: C_cw12diss
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005383
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name: kstop_cc
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900570
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modifier: 345506
modifier: 345494
product: 345482
reactant: 345470
fast: false
reversible: false
name: Start_cwtoR_cw36
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881732
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has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_ccw11
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005586
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value: 0.0212
name: kdemeth
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897391
kinetic law: 337436
product: 337424
reactant: 337412
fast: false
reversible: false
name: Aconfchange_cw39
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897311
kinetic law: 337292
product: 337280
reactant: 337268
fast: false
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name: Aconfchange_cw37
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336918
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species: 882592
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004753
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881432
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boundary condition: false
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initial concentration: NaN
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in compartment: 877675
name: A_cw4
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325599
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species: 880232
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896211
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product: 335273
reactant: 335261
fast: false
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name: Aconfchange_ccw9
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003499
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name: kassC_cc
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319384
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species: 878772
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005506
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name: kr360
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005583
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value: 0.0212
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326034
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species: 880412
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328992
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species: 879952
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318552
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342147
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004429
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002778
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name: kdissR_cc
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319826
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species: 879012
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327536
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883592
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321060
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333380
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331936
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879212
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name: R_ccw38
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004078
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name: k20_cc
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320372
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886452
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879832
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892671
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325199
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316216
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319717
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species: 878952
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005509
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name: kr540
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004759
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name: C_cc
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002343
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882452
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name: A_ccw29
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898390
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name: C_ccwtoE_ccw26
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004204
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name: k20_cw
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335201
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330342
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species: 880692
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882672
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878912
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333234
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878452
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name: R_ccw19
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320043
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species: 879132
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003409
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327246
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species: 880912
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005589
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value: 1.47E-20
name: sigmaphi
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314531
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species: 878292
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896971
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896411
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003514
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315262
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315877
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species: 878812
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005437
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883192
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003406
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338832
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004297
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003051
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345181
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species: 879012
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003511
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name: kassC_cc
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324569
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species: 879772
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002988
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name: R_cw
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343535
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species: 884872
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005386
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name: kstop_cw
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333970
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species: 881292
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004075
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name: C_cw
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886672
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modifier: 316192
product: 316180
reactant: 316168
fast: false
reversible: false
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889751
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product: 322470
reactant: 322458
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893531
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reactant: 330402
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reversible: false
name: C_ccw32diss
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880352
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initial concentration: NaN
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name: C_cw22
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005434
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314967
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species: 878472
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322896
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313602
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004207
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341371
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879152
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005374
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334900
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891611
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340900
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335479
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315600
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325888
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002493
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895491
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339991
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892791
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334323
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896151
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341963
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003658
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319228
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892171
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332511
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332487
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005377
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003385
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323197
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321808
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002346
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004972
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890471
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004288
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002412
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003042
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896751
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005365
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891691
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005164
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877832
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325259
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323113
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002490
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328340
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004420
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894151
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894611
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345905
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346148
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323953
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317183
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320733
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322677
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004978
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882812
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003655
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335128
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336099
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004423
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879372
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003048
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337763
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880132
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005500
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005218
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313180
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327391
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003384
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005592
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005167
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900350
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889131
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887771
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343969
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888591
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339881
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890271
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884272
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004750
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003381
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003159
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331020
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322434
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004975
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003652
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885572
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002349
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893111
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315696
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338905
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329215
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002832
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319192
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003874
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317534
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324086
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322786
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005215
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880992
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320444
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886012
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313758
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314855
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003718
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334116
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004642
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878792
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004531
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892851
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328400
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878092
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004534
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323402
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002565
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004867
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002499
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878712
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887131
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322326
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333017
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339917
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003273
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883692
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003156
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003877
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886092
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886951
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319444
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005212
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345772
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890311
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003153
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004318
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005161
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344619
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878812
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897031
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339771
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003279
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317898
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002415
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002568
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004864
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314230
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003871
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337316
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002496
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888251
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891291
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899550
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333488
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332595
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002619
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333524
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003904
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891331
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005014
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316361
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003389
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003276
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344150
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892391
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reversible: false
name: C_cw4diss
type: Reaction

005017
value: 0.6
name: C_cw
type: LocalParameter

003907
value: 0.6
name: C_cw
type: LocalParameter

332402
stoichiometry: 1.0
species: 880072
type: SpeciesReference

891211
kinetic law: 325575
modifier: 325563
product: 325551
reactant: 325539
fast: false
reversible: false
name: C_ccw17ass
type: Reaction

887471
kinetic law: 318345
product: 318333
reactant: 318321
fast: false
reversible: false
name: R_cw14diss
type: Reaction

337268
stoichiometry: 1.0
species: 882752
type: SpeciesReference

346209
stoichiometry: 1.0
species: 879352
type: SpeciesReference

328123
stoichiometry: 1.0
species: 879472
type: SpeciesReference

329361
stoichiometry: 1.0
species: 880152
type: SpeciesReference

889071
kinetic law: 321252
product: 321240
reactant: 321228
fast: false
reversible: false
name: R_cw9toC_cw9
type: Reaction

887551
kinetic law: 318491
product: 318479
reactant: 318467
fast: false
reversible: false
name: R_cw16diss
type: Reaction

343049
stoichiometry: 1.0
species: 884872
type: SpeciesReference

002418
value: 0.5341
name: kassR_cc
type: LocalParameter

887991
kinetic law: 319288
product: 319276
reactant: 319264
fast: false
reversible: false
name: R_cw27diss
type: Reaction

894851
kinetic law: 332825
product: 332813
reactant: 332801
fast: false
reversible: false
name: C_ccw20toA0_ccw
type: Reaction

002637
value: 0.9314
name: kdissR_cw
type: LocalParameter

321493
stoichiometry: 1.0
species: 879972
type: SpeciesReference

893971
kinetic law: 331224
product: 331212
reactant: 331200
fast: false
reversible: false
name: C_ccw43diss
type: Reaction

317292
stoichiometry: 1.0
species: 879432
type: SpeciesReference

003712
value: 0.03338
name: kdissC_cw
type: LocalParameter

890111
kinetic law: 323137
product: 323125
reactant: 323113
fast: false
reversible: false
name: R_cw35toC_cw35
type: Reaction

324147
stoichiometry: 1.0
species: 879632
type: SpeciesReference

002781
value: 0.9314
name: kdissR_cw
type: LocalParameter

004870
value: 2.07E-9
name: k20_cw
type: LocalParameter

004327
value: 0.6
name: C_cw
type: LocalParameter

329495
stoichiometry: 1.0
species: 880272
type: SpeciesReference

892371
kinetic law: 328315
product: 328303
reactant: 328291
fast: false
reversible: false
name: C_ccw3diss
type: Reaction

889631
kinetic law: 322266
product: 322253
reactant: 322241
fast: false
reversible: false
name: R_cw23toC_cw23
type: Reaction

002616
value: 0.9314
name: kdissR_cc
type: LocalParameter

324905
stoichiometry: 1.0
species: 879912
type: SpeciesReference

337460
stoichiometry: 1.0
species: 882892
type: SpeciesReference

003529
value: 0.1177
name: kassC_cc
type: LocalParameter

003171
value: 810000.0
name: k10_cc
type: LocalParameter

003415
value: 0.1177
name: kassC_cc
type: LocalParameter

343243
stoichiometry: 1.0
species: 878372
type: SpeciesReference

334804
stoichiometry: 1.0
species: 881432
type: SpeciesReference

878192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw13
type: Species

003790
value: 0.03338
name: kdissC_cw
type: LocalParameter

341250
stoichiometry: 1.0
species: 877732
type: SpeciesReference

880572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_ccw27
type: Species

880632
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw29
type: Species

324869
stoichiometry: 1.0
species: 879932
type: SpeciesReference

336504
stoichiometry: 1.0
species: 882332
type: SpeciesReference

883452
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.19571671092132E-17
in compartment: 877675
name: E_ccw9
type: Species

888691
kinetic law: 320565
product: 320553
reactant: 320541
fast: false
reversible: false
name: R_ccw44diss
type: Reaction

003174
value: 0.6
name: R_cc
type: LocalParameter

341479
stoichiometry: 1.0
species: 884872
type: SpeciesReference

889331
kinetic law: 321724
product: 321712
reactant: 321700
fast: false
reversible: false
name: R_ccw15toC_ccw15
type: Reaction

879092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_ccw35
type: Species

884472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0290482001805023
in compartment: 877675
name: E_cw35
type: Species

003481
value: 0.1177
name: kassC_cc
type: LocalParameter

339554
stoichiometry: 1.0
species: 884012
type: SpeciesReference

877732
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw1
type: Species

899910
kinetic law: 343523
modifier: 343511
modifier: 343499
product: 343487
reactant: 343475
fast: false
reversible: false
name: Start_ccwtoR_ccw19
type: Reaction

002817
value: 810000.0
name: k10_cw
type: LocalParameter

004084
value: 2.07E-9
name: k20_cw
type: LocalParameter

320661
stoichiometry: 1.0
species: 879512
type: SpeciesReference

003418
value: 0.1177
name: kassC_cw
type: LocalParameter

005011
value: 0.6
name: C_cc
type: LocalParameter

342507
stoichiometry: 1.0
species: 884892
type: SpeciesReference

898270
kinetic law: 339578
modifier: 339566
product: 339554
fast: false
reversible: false
name: C_ccwtoE_ccw23
type: Reaction

004873
value: 0.6
name: C_cw
type: LocalParameter

882552
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw32
type: Species

005092
value: 2.07E-9
name: k20_cc
type: LocalParameter

002613
value: 0.9314
name: kdissR_cw
type: LocalParameter

326510
stoichiometry: 1.0
species: 880572
type: SpeciesReference

882332
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_ccw26
type: Species

330124
stoichiometry: 1.0
species: 880572
type: SpeciesReference

878572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_ccw22
type: Species

336444
stoichiometry: 1.0
species: 882332
type: SpeciesReference

318333
stoichiometry: 1.0
species: 878192
type: SpeciesReference

890751
kinetic law: 324460
modifier: 324448
product: 324435
reactant: 324423
fast: false
reversible: false
name: C_cw6ass
type: Reaction

890191
kinetic law: 323281
product: 323269
reactant: 323257
fast: false
reversible: false
name: R_cw37toC_cw37
type: Reaction

002784
value: 0.9314
name: kdissR_cc
type: LocalParameter

322932
stoichiometry: 1.0
species: 878972
type: SpeciesReference

881672
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw10
type: Species

004111
value: 0.6
name: C_cw
type: LocalParameter

900450
kinetic law: 345157
modifier: 345145
modifier: 345133
product: 345121
reactant: 345109
fast: false
reversible: false
name: Start_cwtoR_cw33
type: Reaction

319790
stoichiometry: 1.0
species: 878992
type: SpeciesReference

879952
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw12
type: Species

341840
stoichiometry: 1.0
species: 884872
type: SpeciesReference

326132
stoichiometry: 1.0
species: 880452
type: SpeciesReference

003793
value: 0.03338
name: kdissC_cc
type: LocalParameter

894591
kinetic law: 332353
product: 332341
reactant: 332329
fast: false
reversible: false
name: C_cw14toA0_cw
type: Reaction

320878
stoichiometry: 1.0
species: 879632
type: SpeciesReference

002550
value: 0.5341
name: kassR_cc
type: LocalParameter

002811
value: 0.9314
name: kdissR_cw
type: LocalParameter

004549
value: 7.0
name: ks_cc
type: LocalParameter

004210
value: 2.07E-9
name: k20_cc
type: LocalParameter

002610
value: 0.9314
name: kdissR_cc
type: LocalParameter

883932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.04853152731377E-6
in compartment: 877675
name: E_ccw21
type: Species

331345
stoichiometry: 1.0
species: 879492
type: SpeciesReference

314423
stoichiometry: 1.0
species: 878212
type: SpeciesReference

345049
stoichiometry: 1.0
species: 884892
type: SpeciesReference

332377
stoichiometry: 1.0
species: 881292
type: SpeciesReference

899010
kinetic law: 340924
modifier: 340912
product: 340900
fast: false
reversible: false
name: C_cwtoE_cw42
type: Reaction

003595
value: 0.1177
name: kassC_cc
type: LocalParameter

314001
stoichiometry: 1.0
species: 878092
type: SpeciesReference

314038
stoichiometry: 1.0
species: 878072
type: SpeciesReference

004324
value: 2.07E-9
name: k20_cw
type: LocalParameter

881312
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw1
type: Species

319240
stoichiometry: 1.0
species: 878692
type: SpeciesReference

003922
value: 2.07E-9
name: k20_cc
type: LocalParameter

004657
value: 7.0
name: ks_cc
type: LocalParameter

003715
value: 0.03338
name: kdissC_cc
type: LocalParameter

893751
kinetic law: 330826
product: 330814
reactant: 330802
fast: false
reversible: false
name: C_cw38diss
type: Reaction

886712
kinetic law: 316301
modifier: 316289
product: 316277
reactant: 316265
fast: false
reversible: false
name: R_ccw32ass
type: Reaction

893811
kinetic law: 330936
product: 330924
reactant: 330912
fast: false
reversible: false
name: C_ccw39diss
type: Reaction

881712
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw11
type: Species

002814
value: 0.9314
name: kdissR_cc
type: LocalParameter

002787
value: 0.9314
name: kdissR_cw
type: LocalParameter

002970
value: 0.6
name: R_cc
type: LocalParameter

002634
value: 0.9314
name: kdissR_cc
type: LocalParameter

895631
kinetic law: 334238
product: 334225
reactant: 334213
fast: false
reversible: false
name: C_cw40toA0_cw
type: Reaction

004081
value: 0.6
name: C_cc
type: LocalParameter

331597
stoichiometry: 1.0
species: 879632
type: SpeciesReference

005392
value: 2.48
name: kstop_cw
type: LocalParameter

323474
stoichiometry: 1.0
species: 879272
type: SpeciesReference

320938
stoichiometry: 1.0
species: 877892
type: SpeciesReference

325502
stoichiometry: 1.0
species: 880192
type: SpeciesReference

003598
value: 0.1177
name: kassC_cw
type: LocalParameter

003412
value: 0.1177
name: kassC_cw
type: LocalParameter

004321
value: 0.6
name: C_cc
type: LocalParameter

323040
stoichiometry: 1.0
species: 879032
type: SpeciesReference

895051
kinetic law: 333186
product: 333174
reactant: 333162
fast: false
reversible: false
name: C_ccw25toA0_ccw
type: Reaction

323329
stoichiometry: 1.0
species: 879192
type: SpeciesReference

004114
value: 2.07E-9
name: k20_cc
type: LocalParameter

899770
kinetic law: 343097
modifier: 343085
modifier: 343073
product: 343061
reactant: 343049
fast: false
reversible: false
name: Start_cwtoR_cw16
type: Reaction

ORG:
  orgname: Department of Membrane Biochemistry, Max Planck Inst of Biochemistry
n:
  given: Ricardo
  family: del Rosario

332813
stoichiometry: 1.0
species: 881292
type: SpeciesReference

323619
stoichiometry: 1.0
species: 879352
type: SpeciesReference

331501
stoichiometry: 1.0
species: 881292
type: SpeciesReference

327966
stoichiometry: 1.0
species: 881172
type: SpeciesReference

317717
stoichiometry: 1.0
species: 877872
type: SpeciesReference

893011
kinetic law: 329483
product: 329471
reactant: 329459
fast: false
reversible: false
name: C_ccw19diss
type: Reaction

003270
value: 0.6
name: R_cc
type: LocalParameter

883832
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.57582077666219E-5
in compartment: 877675
name: E_cw19
type: Species

003484
value: 0.1177
name: kassC_cw
type: LocalParameter

317667
stoichiometry: 1.0
species: 877892
type: SpeciesReference

003796
value: 0.03338
name: kdissC_cw
type: LocalParameter

894031
kinetic law: 331333
product: 331321
reactant: 331309
fast: false
reversible: false
name: C_cw0toA0_cw
type: Reaction

335491
stoichiometry: 1.0
species: 881812
type: SpeciesReference

331888
stoichiometry: 1.0
species: 879792
type: SpeciesReference

883392
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 4.23583006927007E-17
in compartment: 877675
name: E_cw8
type: Species

884932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: Stop_ccw
type: Species

004765
value: 0.6
name: C_cw
type: LocalParameter

883032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw44
type: Species

900710
kinetic law: 345941
modifier: 345929
modifier: 345917
product: 345905
reactant: 345893
fast: false
reversible: false
name: Start_ccwtoR_ccw39
type: Reaction

003487
value: 0.1177
name: kassC_cc
type: LocalParameter

336906
stoichiometry: 1.0
species: 882552
type: SpeciesReference

318225
stoichiometry: 1.0
species: 878152
type: SpeciesReference

003592
value: 0.1177
name: kassC_cw
type: LocalParameter

885072
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: CheYP_ccw
type: Species

ORG:
  orgname: Department of Membrane Biochemistry, Max Planck Inst of Biochemistry
n:
  given: Ricardo
  family: del Rosario

005571
constant: true
value: 2.07E-9
name: k20_cc
type: Parameter

322823
stoichiometry: 1.0
species: 878912
type: SpeciesReference

342219
stoichiometry: 1.0
species: 878052
type: SpeciesReference

885932
kinetic law: 314411
modifier: 314399
product: 314387
reactant: 314375
fast: false
reversible: false
name: R_cw13ass
type: Reaction

330052
stoichiometry: 1.0
species: 880532
type: SpeciesReference

316905
stoichiometry: 1.0
species: 879272
type: SpeciesReference

332729
stoichiometry: 1.0
species: 880252
type: SpeciesReference

003520
value: 0.1177
name: kassC_cw
type: LocalParameter

341732
stoichiometry: 1.0
species: 877892
type: SpeciesReference

313470
stoichiometry: 1.0
species: 877872
type: SpeciesReference

888151
kinetic law: 319583
product: 319570
reactant: 319557
fast: false
reversible: false
name: R_cw31diss
type: Reaction

879672
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw5
type: Species

342159
stoichiometry: 1.0
species: 878032
type: SpeciesReference

326022
stoichiometry: 1.0
species: 880372
type: SpeciesReference

320360
stoichiometry: 1.0
species: 879352
type: SpeciesReference

879732
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_ccw6
type: Species

893691
kinetic law: 330717
product: 330705
reactant: 330693
fast: false
reversible: false
name: C_ccw36diss
type: Reaction

889851
kinetic law: 322665
product: 322652
reactant: 322640
fast: false
reversible: false
name: R_ccw28toC_ccw28
type: Reaction

331236
stoichiometry: 1.0
species: 881232
type: SpeciesReference

342447
stoichiometry: 1.0
species: 884872
type: SpeciesReference

895851
kinetic law: 334636
product: 334624
reactant: 334612
fast: false
reversible: false
name: Aconfchange_ccw0
type: Reaction

004438
value: 7.0
name: ks_cw
type: LocalParameter

003380
value: 0.1177
name: kassC_cc
type: LocalParameter

334262
stoichiometry: 1.0
species: 881292
type: SpeciesReference

332269
stoichiometry: 1.0
species: 881272
type: SpeciesReference

880432
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw24
type: Species

891831
kinetic law: 327077
modifier: 327065
product: 327053
reactant: 327041
fast: false
reversible: false
name: C_cw33ass
type: Reaction

893611
kinetic law: 330572
product: 330560
reactant: 330548
fast: false
reversible: false
name: C_ccw34diss
type: Reaction

885152
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: Csum_ccw
type: Species

899990
kinetic law: 343765
modifier: 343753
modifier: 343741
product: 343729
reactant: 343717
fast: false
reversible: false
name: Start_ccwtoR_ccw21
type: Reaction

004117
value: 0.6
name: C_cc
type: LocalParameter

005428
value: 2.48
name: kstop_cw
type: LocalParameter

344499
stoichiometry: 1.0
species: 884872
type: SpeciesReference

888731
kinetic law: 320637
product: 320625
reactant: 320613
fast: false
reversible: false
name: R_ccw0toC_ccw0
type: Reaction

004768
value: 2.07E-9
name: k20_cc
type: LocalParameter

883232
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.37025879604211E-23
in compartment: 877675
name: E_cw4
type: Species

896371
kinetic law: 335575
product: 335563
reactant: 335551
fast: false
reversible: false
name: Aconfchange_ccw13
type: Reaction

004213
value: 0.6
name: C_cc
type: LocalParameter

877692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw0
type: Species

897931
kinetic law: 338965
modifier: 338953
product: 338941
fast: false
reversible: false
name: C_cwtoE_cw15
type: Reaction

323728
stoichiometry: 1.0
species: 879412
type: SpeciesReference

002973
value: 810000.0
name: k10_cw
type: LocalParameter

002631
value: 0.9314
name: kdissR_cw
type: LocalParameter

005395
value: 2.48
name: kstop_cc
type: LocalParameter

005574
constant: true
value: 0.6
name: C_cc
type: Parameter

321385
stoichiometry: 1.0
species: 879912
type: SpeciesReference

335382
stoichiometry: 1.0
species: 881752
type: SpeciesReference

345289
stoichiometry: 1.0
species: 884892
type: SpeciesReference

892011
kinetic law: 327512
modifier: 327499
product: 327487
reactant: 327475
fast: false
reversible: false
name: C_ccw37ass
type: Reaction

334552
stoichiometry: 1.0
species: 881292
type: SpeciesReference

003060
value: 0.6
name: R_cw
type: LocalParameter

898310
kinetic law: 339651
modifier: 339639
product: 339627
fast: false
reversible: false
name: C_ccwtoE_ccw24
type: Reaction

002976
value: 0.6
name: R_cw
type: LocalParameter

884132
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 4.37207282605103E-5
in compartment: 877675
name: E_ccw26
type: Species

886172
kinetic law: 314993
modifier: 314980
product: 314967
reactant: 314954
fast: false
reversible: false
name: R_cw19ass
type: Reaction

003063
value: 810000.0
name: k10_cc
type: LocalParameter

003523
value: 0.1177
name: kassC_cc
type: LocalParameter

884492
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 2.93416221216164E-4
in compartment: 877675
name: E_ccw35
type: Species

346560
stoichiometry: 1.0
species: 884952
type: SpeciesReference

004903
value: 0.6
name: C_cc
type: LocalParameter

005398
value: 2.48
name: kstop_cw
type: LocalParameter

005422
value: 2.48
name: kstop_cw
type: LocalParameter

004087
value: 0.6
name: C_cw
type: LocalParameter

340676
stoichiometry: 1.0
species: 884632
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004219
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319156
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species: 878692
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896771
kinetic law: 336304
product: 336292
reactant: 336280
fast: false
reversible: false
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315116
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species: 878532
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320517
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331128
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892151
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reversible: false
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005362
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899330
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modifier: 341756
modifier: 341744
product: 341732
reactant: 341720
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reversible: false
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334912
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878212
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initial concentration: NaN
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name: R_ccw13
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004216
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name: k20_cw
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002331
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883012
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boundary condition: false
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initial concentration: NaN
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004981
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339663
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897711
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modifier: 338406
product: 338394
fast: false
reversible: false
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892091
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modifier: 327696
product: 327683
reactant: 327670
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reversible: false
name: C_ccw39ass
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004900
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900930
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product: 346573
reactant: 346560
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reversible: false
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887231
kinetic law: 317910
product: 317898
reactant: 317886
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reversible: false
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005577
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898530
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modifier: 340039
product: 340027
fast: false
reversible: false
name: C_cwtoE_cw30
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321893
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species: 880192
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002979
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320031
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species: 879172
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333246
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species: 881292
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315310
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900610
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modifier: 345615
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reversible: false
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335297
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species: 881672
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897710
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modifier: 338370
product: 338358
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reversible: false
name: C_cwtoE_cw7
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318939
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species: 878572
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321748
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species: 880112
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003300
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003526
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883792
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321821
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species: 880152
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005425
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319300
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species: 878772
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337160
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species: 882692
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328267
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319680
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315889
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335406
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331092
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331719
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species: 881292
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005389
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322604
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species: 878792
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005209
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name: C_cw
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332475
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species: 880112
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320215
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species: 879272
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330838
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species: 881012
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002334
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324713
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species: 879832
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003054
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004984
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name: k20_cc
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002400
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name: kassR_cc
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317329
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species: 879412
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003373
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type: LocalParameter

897451
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product: 337532
reactant: 337520
fast: false
reversible: false
name: Aconfchange_ccw40
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344270
stoichiometry: 1.0
species: 878712
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005353
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886871
kinetic law: 316977
modifier: 316965
product: 316953
reactant: 316941
fast: false
reversible: false
name: R_ccw39ass
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005176
value: 2.07E-9
name: k20_cc
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880212
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boundary condition: false
has only substance units: false
initial concentration: NaN
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in compartment: 877675
name: C_ccw18
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887611
kinetic law: 318601
product: 318589
reactant: 318576
fast: false
reversible: false
name: R_ccw17diss
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329980
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species: 880492
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888511
kinetic law: 320240
product: 320227
reactant: 320215
fast: false
reversible: false
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320178
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species: 879252
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332620
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species: 880192
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886232
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reversible: false
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004432
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327869
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species: 881132
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897151
kinetic law: 337002
product: 336990
reactant: 336978
fast: false
reversible: false
name: Aconfchange_cw33
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325247
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species: 880052
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336003
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species: 882092
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313312
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species: 877772
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885612
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reactant: 313602
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reversible: false
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324581
stoichiometry: 1.0
species: 879812
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895411
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product: 333825
reactant: 333813
fast: false
reversible: false
name: C_ccw34toA0_ccw
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327487
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species: 881012
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886872
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modifier: 317013
product: 317001
reactant: 316989
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reversible: false
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887811
kinetic law: 318963
product: 318951
reactant: 318939
fast: false
reversible: false
name: R_ccw22diss
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899430
kinetic law: 342075
modifier: 342062
modifier: 342049
product: 342036
reactant: 342024
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reversible: false
name: Start_ccwtoR_ccw7
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333428
stoichiometry: 1.0
species: 881272
type: SpeciesReference

005356
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891451
kinetic law: 326158
modifier: 326145
product: 326132
reactant: 326120
fast: false
reversible: false
name: C_ccw23ass
type: Reaction

880292
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has only substance units: false
initial concentration: NaN
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name: C_ccw20
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338322
stoichiometry: 1.0
species: 883332
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002559
value: 0.9314
name: kdissR_cw
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887691
kinetic law: 318745
product: 318733
reactant: 318721
fast: false
reversible: false
name: R_ccw19diss
type: Reaction

002481
value: 0.5341
name: kassR_cw
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325876
stoichiometry: 1.0
species: 880312
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888371
kinetic law: 319982
product: 319970
reactant: 319958
fast: false
reversible: false
name: R_ccw36diss
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334044
stoichiometry: 1.0
species: 881292
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334335
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species: 881292
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336978
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species: 882592
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878932
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initial concentration: NaN
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name: R_ccw31
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321168
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species: 879792
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321228
stoichiometry: 1.0
species: 878052
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003303
value: 810000.0
name: k10_cc
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003646
value: 0.03338
name: kdissC_cw
type: LocalParameter

003057
value: 810000.0
name: k10_cw
type: LocalParameter

003376
value: 0.1177
name: kassC_cc
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321445
stoichiometry: 1.0
species: 878153
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888851
kinetic law: 320854
product: 320841
reactant: 320829
fast: false
reversible: false
name: R_ccw3toC_ccw3
type: Reaction

005179
value: 0.6
name: C_cc
type: LocalParameter

887831
kinetic law: 318999
product: 318987
reactant: 318975
fast: false
reversible: false
name: R_cw23diss
type: Reaction

005580
constant: true
value: 2.48
name: kstop_cc
type: Parameter

335626
stoichiometry: 1.0
species: 881852
type: SpeciesReference

330560
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species: 880812
type: SpeciesReference

004762
value: 2.07E-9
name: k20_cw
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344988
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species: 884872
type: SpeciesReference

894691
kinetic law: 332535
product: 332523
reactant: 332511
fast: false
reversible: false
name: C_ccw16toA0_ccw
type: Reaction

003868
value: 0.03338
name: kdissC_cw
type: LocalParameter

003306
value: 0.6
name: R_cc
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318140
stoichiometry: 1.0
species: 878152
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883572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.20942184380734E-13
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900150
kinetic law: 344246
modifier: 344234
modifier: 344222
product: 344210
reactant: 344198
fast: false
reversible: false
name: Start_ccwtoR_ccw25
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887011
kinetic law: 317438
product: 317426
reactant: 317414
fast: false
reversible: false
name: R_ccw1diss
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314182
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species: 878132
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345651
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species: 884892
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329140
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species: 880032
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326413
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species: 880532
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003640
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name: kdissC_cw
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315684
stoichiometry: 1.0
species: 878732
type: SpeciesReference

002337
value: 0.5341
name: kassR_cw
type: LocalParameter

004987
value: 0.6
name: C_cc
type: LocalParameter

878672
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw25
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315780
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species: 878772
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342628
stoichiometry: 1.0
species: 884892
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003309
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name: k10_cw
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320589
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species: 879472
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893471
kinetic law: 330317
product: 330305
reactant: 330293
fast: false
reversible: false
name: C_cw31diss
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322689
stoichiometry: 1.0
species: 880632
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323691
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323941
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species: 879512
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317195
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888911
kinetic law: 320962
product: 320950
reactant: 320938
fast: false
reversible: false
name: R_cw5toC_cw5
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900550
kinetic law: 345458
modifier: 345446
modifier: 345434
product: 345422
reactant: 345410
fast: false
reversible: false
name: Start_ccwtoR_ccw35
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320721
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species: 877772
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003371
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name: kassC_cw
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004435
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name: ks_cc
type: LocalParameter

898170
kinetic law: 339397
modifier: 339385
product: 339373
fast: false
reversible: false
name: C_cwtoE_cw21
type: Reaction

316410
stoichiometry: 1.0
species: 879032
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884312
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initial concentration: NaN
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325356
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900070
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reactant: 343957
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reversible: false
name: Start_ccwtoR_ccw23
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003643
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name: kdissC_cc
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005359
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name: kstop_cc
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330415
stoichiometry: 1.0
species: 880732
type: SpeciesReference

005206
value: 2.07E-9
name: k20_cw
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314759
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species: 878352
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346135
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species: 884892
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315491
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333753
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896071
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337604
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species: 882972
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337750
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species: 883012
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003372
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name: kassC_cc
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898970
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fast: false
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name: C_cwtoE_cw41
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326849
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336219
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316989
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316422
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894251
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881072
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338541
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880912
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name: C_cw36
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002487
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004879
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882772
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initial concentration: NaN
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in compartment: 877675
name: A_ccw37
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002553
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893231
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fast: false
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890531
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880052
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885832
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882112
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name: A_cw21
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004546
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333029
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species: 881292
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891931
kinetic law: 327319
modifier: 327307
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reactant: 327283
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321554
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892951
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339049
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species: 883732
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005098
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name: k20_cw
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002409
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888471
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product: 320154
reactant: 320142
fast: false
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889111
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product: 321312
reactant: 321300
fast: false
reversible: false
name: R_cw10toC_cw10
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003865
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name: kdissC_cc
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337532
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species: 882932
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897870
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modifier: 338844
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897231
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339807
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species: 884152
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332801
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species: 880292
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003168
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889491
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product: 322001
reactant: 321989
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reversible: false
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003261
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898610
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modifier: 340183
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891071
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name: C_cw14ass
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005200
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name: k20_cc
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005008
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345169
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species: 884892
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881932
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322799
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319456
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species: 878812
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880852
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name: C_ccw34
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003709
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name: kdissC_cc
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880792
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boundary condition: false
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initial concentration: NaN
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name: C_cw33
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003862
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885452
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modifier: 313240
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342087
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898810
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modifier: 340544
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324098
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336662
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species: 882452
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326619
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species: 880652
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002820
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898690
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modifier: 340328
product: 340315
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reversible: false
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889411
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product: 321857
reactant: 321845
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reversible: false
name: R_ccw17toC_ccw17
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317086
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313891
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891131
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reversible: false
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335515
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species: 881792
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003913
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005203
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320432
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species: 879392
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334104
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species: 881012
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003706
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314867
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313746
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316168
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004654
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003799
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338651
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004543
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329202
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894371
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reactant: 331924
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reversible: false
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005170
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333644
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332693
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895391
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reversible: false
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328412
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878892
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327101
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321676
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003264
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883612
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330632
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003377
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322713
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species: 878852
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003919
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892231
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reversible: false
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886532
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319517
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877952
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005005
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884612
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005095
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895111
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reversible: false
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896871
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reversible: false
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327186
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003649
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892511
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reversible: false
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891711
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reactant: 326751
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reversible: false
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002607
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002406
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328111
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318080
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317935
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004651
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329749
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338431
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323257
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004540
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003165
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324291
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species: 879692
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328811
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species: 879852
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005173
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891791
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reversible: false
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892591
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reactant: 328690
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reversible: false
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321276
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species: 879852
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002484
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881192
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initial concentration: NaN
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name: C_cw43
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337304
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003267
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317886
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species: 878012
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002556
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name: kdissR_cc
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004876
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002403
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003916
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890831
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reactant: 324617
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reversible: false
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005002
value: 2.07E-9
name: k20_cw
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318661
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species: 878372
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321337
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332583
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900230
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modifier: 344463
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reversible: false
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881892
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333536
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species: 881292
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003931
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342568
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339193
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331561
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004333
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002646
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002291
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879892
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boundary condition: false
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initial concentration: NaN
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name: C_ccw10
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002751
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313228
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species: 877772
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881152
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334141
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species: 881032
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002802
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005452
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322386
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species: 878672
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003784
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884772
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887371
kinetic law: 318164
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reversible: false
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331682
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species: 881272
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003472
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name: kassC_cw
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002913
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name: k10_cw
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004102
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332849
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species: 881272
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343183
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species: 878352
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886032
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886372
kinetic law: 315479
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product: 315455
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reversible: false
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341178
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898470
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324617
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319958
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species: 879132
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330196
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species: 880612
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897850
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reversible: false
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003781
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name: kdissC_cc
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899150
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modifier: 341202
product: 341190
reactant: 341178
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reversible: false
name: Start_ccwtoR_ccw0
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327881
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species: 881172
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005646
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334732
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891051
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884072
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322944
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species: 880772
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003180
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335563
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species: 881852
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003703
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name: kdissC_cc
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004621
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name: ks_cc
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003934
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name: k20_cc
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895931
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reversible: false
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880072
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881912
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name: A_cw16
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004336
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name: k20_cw
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896811
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product: 336369
reactant: 336356
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891951
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314435
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879812
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332045
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335153
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899570
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339265
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900210
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894331
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name: C_ccw7toA0_ccw
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882692
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name: A_ccw35
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339337
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003186
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326861
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species: 880752
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005640
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327379
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species: 880932
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889271
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891311
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name: C_cw20ass
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005242
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330112
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species: 880612
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336432
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species: 882292
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315395
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896951
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318369
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315455
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species: 878672
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321627
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species: 878252
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004627
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005080
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895711
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reactant: 334359
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897011
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314663
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346499
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species: 884892
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002805
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315744
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species: 878792
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342809
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species: 884872
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004339
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003700
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896891
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fast: false
reversible: false
name: Aconfchange_ccw26
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004624
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880372
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317280
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336183
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889991
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reversible: false
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343717
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328219
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337280
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344559
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species: 884892
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002649
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886692
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product: 316229
reactant: 316216
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reversible: false
name: R_cw32ass
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002910
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name: R_cc
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003892
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name: k20_cw
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897630
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product: 338066
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005643
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900850
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product: 346329
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reversible: false
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882612
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name: A_ccw33
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003183
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880752
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initial concentration: NaN
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name: C_cw32
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005568
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891391
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product: 325986
reactant: 325974
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005455
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name: kstop_cc
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885012
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initial concentration: NaN
initial amount: 1.0
in compartment: 877675
name: M1
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005565
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name: kassC_cc
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333996
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species: 880952
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333210
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346389
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894071
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899630
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318878
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004912
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884552
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339699
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318902
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896611
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name: Aconfchange_ccw19
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004489
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name: ks_cc
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004993
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name: C_cw
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330004
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species: 880552
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317049
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species: 879332
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003670
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name: kdissC_cw
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319886
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species: 879092
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881752
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894931
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reactant: 332945
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335418
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900590
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897371
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reactant: 337376
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reversible: false
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886852
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322871
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species: 880732
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004408
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name: k20_cw
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893891
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product: 331068
reactant: 331056
fast: false
reversible: false
name: C_ccw41diss
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897690
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modifier: 338298
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fast: false
reversible: false
name: C_cwtoE_cw6
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314375
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320104
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species: 879212
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321736
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species: 878312
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003538
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name: kassC_cw
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003312
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name: R_cw
type: LocalParameter

326655
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species: 880632
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335261
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species: 881652
type: SpeciesReference

884812
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884352
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886851
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345229
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002808
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004051
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345410
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891671
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004915
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005458
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336292
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003535
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894631
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881452
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896231
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004273
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896591
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320190
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002757
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005350
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004108
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343607
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320068
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315104
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003478
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319096
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338176
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322001
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004105
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332233
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332305
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002916
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889551
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313119
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325647
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004402
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337340
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342459
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004270
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321373
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005562
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329531
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341672
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002643
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004990
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883312
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333849
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004330
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893551
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323547
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888011
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003475
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002640
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329349
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343475
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328063
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897691
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004483
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004777
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321084
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893931
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344078
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002919
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887851
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334624
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004054
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879172
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003673
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318576
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341720
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002754
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004405
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325539
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330088
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003532
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002328
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004492
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003679
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887091
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003024
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336075
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897750
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325344
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005290
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002430
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894491
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002391
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318297
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320577
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004048
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316458
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316023
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900010
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881232
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897751
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335044
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336395
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336207
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336540
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002700
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881012
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890411
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898030
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898110
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345591
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892771
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322652
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004909
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005347
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345711
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892831
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314723
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004849
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890491
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003318
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336317
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004774
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896731
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886932
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331453
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335638
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892191
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878732
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318007
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003676
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337677
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326425
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004846
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894131
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004999
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002325
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002433
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881812
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329603
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886931
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322458
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888991
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879392
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337136
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003258
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002547
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892431
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005344
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344631
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313662
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334408
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004771
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004267
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894411
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324484
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003315
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003021
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336942
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333355
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888231
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334032
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898750
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890251
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895231
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004996
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002436
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324725
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002322
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004264
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004906
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330778
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330802
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889151
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894711
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331707
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884292
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005293
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002394
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327475
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882252
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005188
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889771
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005341
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323765
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340063
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005185
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340496
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335346
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species: 881732
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002439
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313807
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319570
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003177
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004552
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899270
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886752
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334516
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344330
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005299
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321349
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329090
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893331
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reversible: false
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003928
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002544
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003895
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324375
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004840
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344740
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003255
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005233
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322169
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005296
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340171
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322725
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330669
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887151
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327723
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003252
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313554
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002397
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316711
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332741
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325064
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005083
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887152
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reversible: false
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894551
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reactant: 332257
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344862
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881372
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003925
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005239
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005461
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879412
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897590
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893031
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329239
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326703
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005649
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336650
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342099
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882832
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003898
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317558
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320469
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005089
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880152
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897591
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891271
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004555
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005182
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317607
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316567
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882192
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003787
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337099
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species: 882692
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318721
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321566
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887751
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reversible: false
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005086
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318116
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900370
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340388
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004558
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004843
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317486
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002541
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889051
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reversible: false
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005236
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887951
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327439
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003027
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900430
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reversible: false
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337568
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885592
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887491
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324038
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885092
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330184
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883052
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889031
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reversible: false
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005559
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003946
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334684
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003192
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343170
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334720
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887971
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003102
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328183
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318431
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319742
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004348
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878172
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002991
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004633
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343595
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319264
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338248
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889831
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893671
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331815
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324629
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889611
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320914
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895871
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002658
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004345
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002994
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323450
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889691
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883432
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884452
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331573
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002763
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313216
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897091
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003943
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897950
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889311
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879072
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322398
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888671
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878872
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888751
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343837
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005440
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880592
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003460
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342024
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003772
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890731
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315068
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882532
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892319
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326993
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331670
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002901
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332837
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334864
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004636
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003105
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881392
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340315
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326365
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879972
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343729
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336171
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003195
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338795
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883632
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316229
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319023
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003880
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318503
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329471
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005443
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900290
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878232
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322241
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005556
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003198
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335165
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330221
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881872
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338030
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886592
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893771
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005230
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886732
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898550
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332032
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321953
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004639
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892071
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002760
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330293
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884672
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003940
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899290
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318357
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004060
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319668
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315443
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886731
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320685
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314675
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005446
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004927
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877812
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336280
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878512
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345422
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326084
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004063
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878392
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322097
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003321
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003547
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342761
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004285
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319480
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890971
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317341
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880492
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314954
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879692
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337448
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888171
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319132
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004498
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003466
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896691
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name: Aconfchange_ccw21
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880652
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has only substance units: false
initial concentration: NaN
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in compartment: 877675
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346377
stoichiometry: 1.0
species: 884892
type: SpeciesReference

005553
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value: 0.5341
name: kassR_cc
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885132
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: Csum_cw
type: Species

880412
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has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
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320793
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species: 877812
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318914
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897530
kinetic law: 337738
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product: 337713
reactant: 337701
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name: Aconfchange_cw43
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319898
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species: 879052
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330330
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species: 880732
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334936
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species: 881472
type: SpeciesReference

004924
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type: LocalParameter

318866
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species: 878532
type: SpeciesReference

003469
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name: kassC_cc
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314387
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species: 878232
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321845
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species: 878372
type: SpeciesReference

898330
kinetic law: 339687
modifier: 339675
product: 339663
fast: false
reversible: false
name: C_cwtoE_cw25
type: Reaction

320116
stoichiometry: 1.0
species: 879172
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005449
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name: kstop_cc
type: LocalParameter

877752
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_ccw1
type: Species

882312
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boundary condition: false
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initial concentration: NaN
initial amount: 0.0
in compartment: 877675
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315298
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species: 878572
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335273
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species: 881692
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883212
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initial concentration: NaN
initial amount: 1.93861154940201E-27
in compartment: 877675
name: E_ccw3
type: Species

897531
kinetic law: 337787
product: 337775
product: 337763
reactant: 337750
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reversible: false
name: Aconfchange_ccw43
type: Reaction

878592
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has only substance units: false
initial concentration: NaN
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in compartment: 877675
name: R_cw23
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337993
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species: 883152
type: SpeciesReference

898250
kinetic law: 339542
modifier: 339530
product: 339518
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reversible: false
name: C_cwtoE_cw23
type: Reaction

896351
kinetic law: 335539
product: 335527
reactant: 335515
fast: false
reversible: false
name: Aconfchange_cw13
type: Reaction

003324
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name: R_cw
type: LocalParameter

342821
stoichiometry: 1.0
species: 878232
type: SpeciesReference

323559
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species: 881112
type: SpeciesReference

886152
kinetic law: 314941
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reversible: false
name: R_ccw18ass
type: Reaction

319372
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species: 878812
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883912
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has only substance units: false
initial concentration: NaN
initial amount: 1.03804165223578E-4
in compartment: 877675
name: E_cw21
type: Species

894111
kinetic law: 331477
product: 331465
reactant: 331453
fast: false
reversible: false
name: C_cw2toA0_cw
type: Reaction

895591
kinetic law: 334165
product: 334153
reactant: 334141
fast: false
reversible: false
name: C_cw39toA0_cw
type: Reaction

004789
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name: C_cw
type: LocalParameter

004495
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name: ks_cc
type: LocalParameter

002652
value: 0.9314
name: kdissR_cc
type: LocalParameter

003463
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name: kassC_cc
type: LocalParameter

318589
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species: 878332
type: SpeciesReference

884112
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.00432834981103483
in compartment: 877675
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328075
stoichiometry: 1.0
species: 881252
type: SpeciesReference

343487
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species: 878452
type: SpeciesReference

004066
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name: k20_cc
type: LocalParameter

334612
stoichiometry: 1.0
species: 881292
type: SpeciesReference

002907
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name: k10_cc
type: LocalParameter

877892
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw5
type: Species

331212
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species: 881172
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321096
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331924
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344138
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species: 884872
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330076
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species: 880592
type: SpeciesReference

004921
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name: C_cw
type: LocalParameter

319814
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species: 879052
type: SpeciesReference

322181
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species: 880352
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003544
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name: kassC_cw
type: LocalParameter

003661
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name: kdissC_cc
type: LocalParameter

899030
kinetic law: 340960
modifier: 340948
product: 340936
fast: false
reversible: false
name: C_ccwtoE_ccw42
type: Reaction

328980
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899350
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modifier: 341816
modifier: 341804
product: 341792
reactant: 341780
fast: false
reversible: false
name: Start_ccwtoR_ccw5
type: Reaction

004417
value: 0.6
name: C_cc
type: LocalParameter

002766
value: 0.9314
name: kdissR_cc
type: LocalParameter

327524
stoichiometry: 1.0
species: 880992
type: SpeciesReference

002904
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name: R_cw
type: LocalParameter

327670
stoichiometry: 1.0
species: 881052
type: SpeciesReference

332945
stoichiometry: 1.0
species: 880372
type: SpeciesReference

004069
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name: C_cc
type: LocalParameter

336736
stoichiometry: 1.0
species: 882492
type: SpeciesReference

335847
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species: 881972
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332197
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species: 881272
type: SpeciesReference

893831
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product: 330960
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reversible: false
name: C_cw40diss
type: Reaction

897731
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modifier: 338480
product: 338468
fast: false
reversible: false
name: C_ccwtoE_ccw8
type: Reaction

895651
kinetic law: 334274
product: 334262
reactant: 334250
fast: false
reversible: false
name: C_ccw40toA0_ccw
type: Reaction

884892
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has only substance units: false
initial concentration: NaN
initial amount: 0.99
in compartment: 877675
name: Start_ccw
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900910
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modifier: 346535
modifier: 346523
product: 346511
reactant: 346499
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reversible: false
name: Start_ccwtoR_ccw44
type: Reaction

323341
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species: 880992
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325635
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species: 880212
type: SpeciesReference

318649
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species: 878412
type: SpeciesReference

320805
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species: 879592
type: SpeciesReference

004414
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name: k20_cc
type: LocalParameter

879292
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_ccw40
type: Species

884192
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0168206672232275
in compartment: 877675
name: E_cw28
type: Species

005550
constant: true
value: 2.48
name: kstop_cw
type: Parameter

002769
value: 0.9314
name: kdissR_cw
type: LocalParameter

334576
stoichiometry: 1.0
species: 881272
type: SpeciesReference

340748
stoichiometry: 1.0
species: 884672
type: SpeciesReference

335786
stoichiometry: 1.0
species: 881972
type: SpeciesReference

336882
stoichiometry: 1.0
species: 882572
type: SpeciesReference

004282
value: 2.07E-9
name: k20_cc
type: LocalParameter

324279
stoichiometry: 1.0
species: 879652
type: SpeciesReference

897730
kinetic law: 338455
modifier: 338443
product: 338431
fast: false
reversible: false
name: C_cwtoE_cw8
type: Reaction

894051
kinetic law: 331369
product: 331357
reactant: 331345
fast: false
reversible: false
name: C_ccw0toA0_ccw
type: Reaction

883772
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.19541780392875E-8
in compartment: 877675
name: E_ccw17
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887071
kinetic law: 317583
product: 317570
reactant: 317558
fast: false
reversible: false
name: R_ccw3diss
type: Reaction

004342
value: 2.07E-9
name: k20_cc
type: LocalParameter

329543
stoichiometry: 1.0
species: 880252
type: SpeciesReference

002655
value: 0.9314
name: kdissR_cw
type: LocalParameter

900630
kinetic law: 345699
modifier: 345687
modifier: 345675
product: 345663
reactant: 345651
fast: false
reversible: false
name: Start_ccwtoR_ccw37
type: Reaction

002997
value: 810000.0
name: k10_cw
type: LocalParameter

883992
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 4.9451226337277E-4
in compartment: 877675
name: E_cw23
type: Species

003393
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name: kassC_cw
type: LocalParameter

331465
stoichiometry: 1.0
species: 881272
type: SpeciesReference

897471
kinetic law: 337580
product: 337568
reactant: 337556
fast: false
reversible: false
name: Aconfchange_cw41
type: Reaction

885852
kinetic law: 314218
modifier: 314206
product: 314194
reactant: 314182
fast: false
reversible: false
name: R_cw11ass
type: Reaction

881092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_ccw40
type: Species

003997
value: 0.6
name: C_cc
type: LocalParameter

885912
kinetic law: 314363
modifier: 314351
product: 314339
reactant: 314327
fast: false
reversible: false
name: R_ccw12ass
type: Reaction

341238
stoichiometry: 1.0
species: 884872
type: SpeciesReference

004786
value: 2.07E-9
name: k20_cw
type: LocalParameter

318793
stoichiometry: 1.0
species: 878492
type: SpeciesReference

321421
stoichiometry: 1.0
species: 879932
type: SpeciesReference

343957
stoichiometry: 1.0
species: 884892
type: SpeciesReference

892971
kinetic law: 329410
product: 329398
reactant: 329385
fast: false
reversible: false
name: C_ccw18diss
type: Reaction

004708
value: 2.07E-9
name: k20_cc
type: LocalParameter

879752
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw7
type: Species

891891
kinetic law: 327222
modifier: 327210
product: 327198
reactant: 327186
fast: false
reversible: false
name: C_ccw34ass
type: Reaction

890611
kinetic law: 324123
modifier: 324110
product: 324098
reactant: 324086
fast: false
reversible: false
name: C_ccw2ass
type: Reaction

337665
stoichiometry: 1.0
species: 882972
type: SpeciesReference

884952
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.0
in compartment: 877675
name: SRII487
type: Species

W3 CDTF: Mon Mar 17 10:31:42 GMT 2008

002313
value: 0.5341
name: kassR_cw
type: LocalParameter

003249
value: 810000.0
name: k10_cw
type: LocalParameter

003664
value: 0.03338
name: kdissC_cw
type: LocalParameter

895431
kinetic law: 333873
product: 333861
reactant: 333849
fast: false
reversible: false
name: C_cw35toA0_cw
type: Reaction

897171
kinetic law: 337038
product: 337026
reactant: 337014
fast: false
reversible: false
name: Aconfchange_ccw33
type: Reaction

004858
value: 2.07E-9
name: k20_cw
type: LocalParameter

002421
value: 0.5341
name: kassR_cw
type: LocalParameter

330948
stoichiometry: 1.0
species: 881072
type: SpeciesReference

887631
kinetic law: 318637
product: 318625
reactant: 318613
fast: false
reversible: false
name: R_cw18diss
type: Reaction

886252
kinetic law: 315189
modifier: 315177
product: 315164
reactant: 315152
fast: false
reversible: false
name: R_cw21ass
type: Reaction

328774
stoichiometry: 1.0
species: 879832
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880872
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw35
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888311
kinetic law: 319874
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name: R_cw35diss
type: Reaction

315552
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species: 878712
type: SpeciesReference

888391
kinetic law: 320018
product: 320006
reactant: 319994
fast: false
reversible: false
name: R_cw37diss
type: Reaction

004411
value: 0.6
name: C_cw
type: LocalParameter

003036
value: 0.6
name: R_cw
type: LocalParameter

337775
stoichiometry: 1.0
species: 883052
type: SpeciesReference

003395
value: 0.1177
name: kassC_cc
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003667
value: 0.03338
name: kdissC_cc
type: LocalParameter

002316
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name: kassR_cc
type: LocalParameter

885792
kinetic law: 314074
modifier: 314062
product: 314050
reactant: 314038
fast: false
reversible: false
name: R_ccw9ass
type: Reaction

W3 CDTF: Fri Jan 20 18:25:13 GMT 2012

336063
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species: 882092
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900770
kinetic law: 346123
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name: Start_cwtoR_cw41
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880272
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has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw20
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318285
stoichiometry: 1.0
species: 878212
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899410
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modifier: 341999
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product: 341975
reactant: 341963
fast: false
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name: Start_cwtoR_cw7
type: Reaction

891151
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modifier: 325418
product: 325405
reactant: 325393
fast: false
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name: C_cw16ass
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893191
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product: 329798
reactant: 329786
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name: C_cw24diss
type: Reaction

891471
kinetic law: 326208
modifier: 326195
product: 326182
reactant: 326170
fast: false
reversible: false
name: C_cw24ass
type: Reaction

003541
value: 0.1177
name: kassC_cc
type: LocalParameter

003396
value: 0.1177
name: kassC_cw
type: LocalParameter

335056
stoichiometry: 1.0
species: 881572
type: SpeciesReference

885992
kinetic law: 314555
modifier: 314543
product: 314531
reactant: 314519
fast: false
reversible: false
name: R_ccw14ass
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316035
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species: 878912
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317414
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species: 877752
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325974
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species: 880352
type: SpeciesReference

W3 CDTF: Fri Jan 20 18:25:13 GMT 2012

316180
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species: 878972
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330439
stoichiometry: 1.0
species: 880792
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323740
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species: 881212
type: SpeciesReference

005335
value: 2.48
name: kstop_cc
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328545
stoichiometry: 1.0
species: 879752
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878952
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
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338394
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species: 883372
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333777
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species: 880832
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883552
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boundary condition: false
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initial concentration: NaN
initial amount: 1.19731882553901E-11
in compartment: 877675
name: E_cw12
type: Species

002310
value: 0.5341
name: kassR_cc
type: LocalParameter

887291
kinetic law: 318020
product: 318007
reactant: 317995
fast: false
reversible: false
name: R_ccw9diss
type: Reaction

002424
value: 0.5341
name: kassR_cc
type: LocalParameter

003030
value: 0.6
name: R_cc
type: LocalParameter

004276
value: 2.07E-9
name: k20_cw
type: LocalParameter

003397
value: 0.1177
name: kassC_cc
type: LocalParameter

323815
stoichiometry: 1.0
species: 881252
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335991
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species: 882052
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891511
kinetic law: 326304
modifier: 326292
product: 326280
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fast: false
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name: C_cw25ass
type: Reaction

330814
stoichiometry: 1.0
species: 880952
type: SpeciesReference

002538
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name: kassR_cc
type: LocalParameter

332523
stoichiometry: 1.0
species: 881292
type: SpeciesReference

313989
stoichiometry: 1.0
species: 878052
type: SpeciesReference

004918
value: 2.07E-9
name: k20_cw
type: LocalParameter

004561
value: 7.0
name: ks_cc
type: LocalParameter

886891
kinetic law: 317074
modifier: 317061
product: 317049
reactant: 317037
fast: false
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name: R_ccw40ass
type: Reaction

323125
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species: 880872
type: SpeciesReference

003994
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name: k20_cc
type: LocalParameter

327053
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species: 880832
type: SpeciesReference

888191
kinetic law: 319656
product: 319644
reactant: 319632
fast: false
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name: R_cw32diss
type: Reaction

879312
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has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw41
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323777
stoichiometry: 1.0
species: 881232
type: SpeciesReference

004705
value: 0.6
name: C_cw
type: LocalParameter

003246
value: 0.6
name: R_cc
type: LocalParameter

317741
stoichiometry: 1.0
species: 877932
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333090
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329616
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species: 880292
type: SpeciesReference

ORG:
  orgname: Department of Membrane Biochemistry, Max Planck Inst of Biochemistry
n:
  given: Ricardo
  family: del Rosario

002535
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name: kassR_cw
type: LocalParameter

886892
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modifier: 317110
product: 317098
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name: R_cw41ass
type: Reaction

314807
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898190
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modifier: 339421
product: 339409
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name: C_ccwtoE_ccw21
type: Reaction

900090
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modifier: 344054
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product: 344030
reactant: 344017
fast: false
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name: Start_cwtoR_cw24
type: Reaction

329761
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329016
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species: 880012
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003991
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type: LocalParameter

005332
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name: kstop_cw
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878652
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initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_ccw24
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893451
kinetic law: 330281
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reactant: 330257
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reversible: false
name: C_ccw30diss
type: Reaction

333342
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330766
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884572
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boundary condition: false
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initial concentration: NaN
initial amount: 1.4081566745238E-5
in compartment: 877675
name: E_ccw37
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003033
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name: k10_cw
type: LocalParameter

003327
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name: k10_cc
type: LocalParameter

004702
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name: k20_cw
type: LocalParameter

313650
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323016
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325405
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898990
kinetic law: 340888
modifier: 340876
product: 340864
fast: false
reversible: false
name: C_ccwtoE_ccw41
type: Reaction

004279
value: 0.6
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004783
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336954
stoichiometry: 1.0
species: 882612
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332450
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334359
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species: 881152
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877675
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size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

887211
kinetic law: 317874
product: 317862
reactant: 317850
fast: false
reversible: false
name: R_ccw7diss
type: Reaction

321204
stoichiometry: 1.0
species: 879812
type: SpeciesReference

330657
stoichiometry: 1.0
species: 880912
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342989
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330705
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species: 880892
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887411
kinetic law: 318237
product: 318225
reactant: 318213
fast: false
reversible: false
name: R_ccw12diss
type: Reaction

005221
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name: C_cw
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890511
kinetic law: 323880
modifier: 323867
product: 323854
reactant: 323841
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type: Reaction

893251
kinetic law: 329920
product: 329907
reactant: 329895
fast: false
reversible: false
name: C_ccw25diss
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900410
kinetic law: 345037
modifier: 345025
modifier: 345013
product: 345000
reactant: 344988
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reversible: false
name: Start_cwtoR_cw32
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003240
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894271
kinetic law: 331767
product: 331755
reactant: 331743
fast: false
reversible: false
name: C_cw6toA0_cw
type: Reaction

003778
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type: LocalParameter

882752
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boundary condition: false
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name: A_cw37
type: Species

325113
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892291
kinetic law: 328171
product: 328159
reactant: 328147
fast: false
reversible: false
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type: Reaction

888451
kinetic law: 320129
product: 320116
reactant: 320104
fast: false
reversible: false
name: R_ccw38diss
type: Reaction

888531
kinetic law: 320276
product: 320264
reactant: 320252
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reversible: false
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type: Reaction

893991
kinetic law: 331261
product: 331249
reactant: 331236
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reversible: false
name: C_cw44diss
type: Reaction

894831
kinetic law: 332789
product: 332777
reactant: 332765
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reversible: false
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type: Reaction

889471
kinetic law: 321977
product: 321965
reactant: 321953
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reversible: false
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type: Reaction

897251
kinetic law: 337184
product: 337172
reactant: 337160
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reversible: false
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885632
kinetic law: 313686
modifier: 313674
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reversible: false
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898630
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modifier: 340219
product: 340207
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reversible: false
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329968
stoichiometry: 1.0
species: 880532
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005071
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327736
stoichiometry: 1.0
species: 881112
type: SpeciesReference

890131
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product: 323161
reactant: 323149
fast: false
reversible: false
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type: Reaction

005197
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326909
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species: 880772
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004780
value: 2.07E-9
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002298
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317959
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323233
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003108
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325743
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317850
stoichiometry: 1.0
species: 877992
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885432
kinetic law: 313204
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reversible: false
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003189
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name: k10_cw
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004564
value: 7.0
name: ks_cw
type: LocalParameter

889251
kinetic law: 321578
product: 321566
reactant: 321554
fast: false
reversible: false
name: R_ccw13toC_ccw13
type: Reaction

325052
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species: 879972
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334504
stoichiometry: 1.0
species: 881232
type: SpeciesReference

334468
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species: 881212
type: SpeciesReference

894351
kinetic law: 331912
product: 331900
reactant: 331888
fast: false
reversible: false
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344752
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species: 878872
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897631
kinetic law: 338126
modifier: 338114
product: 338102
fast: false
reversible: false
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003243
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324387
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species: 879732
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002532
value: 0.5341
name: kassR_cc
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003883
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890591
kinetic law: 324074
modifier: 324062
product: 324050
reactant: 324038
fast: false
reversible: false
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004852
value: 2.07E-9
name: k20_cc
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002427
value: 0.5341
name: kassR_cw
type: LocalParameter

895371
kinetic law: 333765
product: 333753
reactant: 333741
fast: false
reversible: false
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type: Reaction

314050
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892211
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modifier: 327990
product: 327978
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fast: false
reversible: false
name: C_ccw42ass
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322314
stoichiometry: 1.0
species: 878632
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331140
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species: 881132
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877972
constant: false
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initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw7
type: Species

002319
value: 0.5341
name: kassR_cw
type: LocalParameter

888871
kinetic law: 320890
product: 320878
reactant: 320866
fast: false
reversible: false
name: R_cw4toC_cw4
type: Reaction

337086
stoichiometry: 1.0
species: 882652
type: SpeciesReference

005338
value: 2.48
name: kstop_cw
type: LocalParameter

005074
value: 2.07E-9
name: k20_cw
type: LocalParameter

890811
kinetic law: 324605
modifier: 324593
product: 324581
reactant: 324569
fast: false
reversible: false
name: C_ccw7ass
type: Reaction

W3 CDTF: Fri Jan 20 18:25:13 GMT 2012

317498
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species: 877752
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900130
kinetic law: 344186
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product: 344150
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reversible: false
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type: Reaction

004855
value: 0.6
name: C_cc
type: LocalParameter

005191
value: 0.6
name: C_cc
type: LocalParameter

002292
value: 0.5341
name: kassR_cc
type: LocalParameter

896011
kinetic law: 334924
product: 334912
reactant: 334900
fast: false
reversible: false
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type: Reaction

316796
stoichiometry: 1.0
species: 879192
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878012
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has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw8
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005224
value: 2.07E-9
name: k20_cc
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881652
constant: false
boundary condition: false
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initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_ccw9
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345784
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327427
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899710
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328883
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892531
kinetic law: 328606
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891731
kinetic law: 326837
modifier: 326824
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reactant: 326800
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reversible: false
name: C_ccw30ass
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003889
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name: C_cc
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337556
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species: 882912
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895131
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product: 333318
reactant: 333306
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reversible: false
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329128
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species: 880072
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003039
value: 810000.0
name: k10_cc
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346269
stoichiometry: 1.0
species: 879372
type: SpeciesReference

003937
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name: C_cc
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005227
value: 0.6
name: C_cc
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003886
value: 2.07E-9
name: k20_cc
type: LocalParameter

884792
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boundary condition: false
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initial concentration: NaN
initial amount: 4.85675846421248E-15
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326571
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335919
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899790
kinetic law: 343158
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modifier: 343134
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name: Start_ccwtoR_ccw16
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322506
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326715
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species: 880692
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337884
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883852
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337208
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328291
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314519
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896091
kinetic law: 335068
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reactant: 335044
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name: Aconfchange_ccw6
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315975
stoichiometry: 1.0
species: 878852
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328436
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species: 879692
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005077
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330548
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species: 880852
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895071
kinetic law: 333222
product: 333210
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317680
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species: 877852
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316555
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species: 879092
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003775
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name: kdissC_cc
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002295
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name: kassR_cw
type: LocalParameter

004567
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name: ks_cc
type: LocalParameter

004630
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name: ks_cw
type: LocalParameter

005194
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name: k20_cw
type: LocalParameter

881172
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boundary condition: false
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initial concentration: NaN
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316603
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884712
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initial concentration: NaN
initial amount: 9.40836649930441E-10
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name: E_cw41
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002667
value: 0.9314
name: kdissR_cw
type: LocalParameter

003003
value: 810000.0
name: k10_cc
type: LocalParameter

878153
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
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327683
stoichiometry: 1.0
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002388
value: 0.5341
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890011
kinetic law: 322956
product: 322944
reactant: 322932
fast: false
reversible: false
name: R_ccw32toC_ccw32
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324243
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317971
stoichiometry: 1.0
species: 878012
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887391
kinetic law: 318200
product: 318188
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fast: false
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328594
stoichiometry: 1.0
species: 879732
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003096
value: 0.6
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type: LocalParameter

893871
kinetic law: 331044
product: 331032
reactant: 331020
fast: false
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888971
kinetic law: 321072
product: 321060
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type: Reaction

886832
kinetic law: 316832
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name: R_cw38ass
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340424
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894951
kinetic law: 333005
product: 332993
reactant: 332981
fast: false
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005113
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334588
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species: 881312
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346647
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species: 884952
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341190
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329834
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317813
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878152
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initial concentration: NaN
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323377
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900530
kinetic law: 345398
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005062
value: 2.07E-9
name: k20_cw
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313939
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317789
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species: 877912
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004699
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338577
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313903
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species: 878052
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002307
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333560
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332185
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316470
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320264
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890431
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product: 323704
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344874
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313421
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species: 877852
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004696
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004933
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338687
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883492
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003556
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003763
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322859
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003697
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name: kdissC_cc
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335810
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331200
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005065
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895171
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reactant: 333380
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type: Reaction

332777
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species: 881272
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003619
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004015
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346317
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species: 884872
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334648
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329325
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899250
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002385
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002664
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329398
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species: 880172
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894651
kinetic law: 332463
product: 332450
reactant: 332438
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325551
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313566
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species: 877912
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327283
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004609
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313710
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886831
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891651
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modifier: 326631
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002715
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323523
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335773
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885752
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889211
kinetic law: 321505
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328231
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324520
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879532
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891191
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880692
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888651
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004936
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878972
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892411
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899830
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319336
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316663
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325101
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003613
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328944
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004711
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003766
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003006
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319862
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003694
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334948
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900390
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reversible: false
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314579
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335600
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species: 881872
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004012
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334008
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324809
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345953
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320336
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002661
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897990
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reversible: false
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339844
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897191
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319120
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003009
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328303
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887871
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reversible: false
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333126
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322422
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331285
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002718
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004606
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893911
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reversible: false
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880732
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888551
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003829
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003559
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003099
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329103
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893051
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002940
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890651
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340640
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892491
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889931
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005116
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004939
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003616
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345362
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328654
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892751
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004717
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323631
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319970
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320697
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886911
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reversible: false
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003691
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884012
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boundary condition: false
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004690
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898850
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reversible: false
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895551
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324677
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004603
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003769
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886052
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reversible: false
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325211
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species: 880072
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004828
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345844
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328666
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331393
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323802
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892891
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879872
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317134
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881132
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316325
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887171
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reversible: false
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004360
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337640
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898910
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reversible: false
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339409
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337799
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005479
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886132
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reversible: false
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892811
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reactant: 329090
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reversible: false
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005119
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345470
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species: 884872
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004168
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322531
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891971
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reversible: false
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880092
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339735
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893271
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315019
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337713
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species: 884912
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890371
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reversible: false
name: R_ccw41toC_ccw41
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004714
value: 2.07E-9
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003610
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name: kassC_cw
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317244
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species: 879412
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346027
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species: 879292
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880952
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891031
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891591
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330305
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884092
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884212
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881472
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name: A_cw5
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897351
kinetic law: 337364
product: 337352
reactant: 337340
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reversible: false
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003117
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339085
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325840
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896251
kinetic law: 335358
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004600
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314819
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species: 878412
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344571
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335883
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341081
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species: 884852
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880312
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332293
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333452
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887511
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002301
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324472
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species: 879732
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002457
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317631
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species: 877872
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004822
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890351
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product: 323559
reactant: 323547
fast: false
reversible: false
name: R_cw41toC_cw41
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005476
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321012
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species: 877932
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332669
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species: 881292
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003093
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340936
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species: 884772
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003111
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894311
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318176
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003448
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329725
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883112
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320902
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327573
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332109
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895791
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333789
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885032
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888211
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891251
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882932
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331827
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species: 881272
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003090
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323149
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329895
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884972
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325986
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319276
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322968
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003349
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003114
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319754
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species: 878972
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002382
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888071
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316953
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320841
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319408
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880392
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893571
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005269
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004018
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005068
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334225
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004825
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002454
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889891
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002304
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887591
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880012
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003000
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325295
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004930
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005622
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004693
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884432
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004579
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896111
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339627
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900030
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896471
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003988
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330996
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327137
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328448
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881552
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336480
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005625
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899130
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320625
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339301
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895451
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003445
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342700
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321700
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886352
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346257
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005485
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005278
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004174
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004249
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332329
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003442
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004171
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338941
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890911
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332070
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315201
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003346
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004354
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898450
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322470
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894191
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340712
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328871
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877872
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005482
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322073
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896711
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002451
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878272
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315164
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003345
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317462
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339013
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005326
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333813
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896191
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331176
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002520
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900870
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896311
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reactant: 335442
fast: false
reversible: false
name: Aconfchange_cw12
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004462
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338468
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species: 883412
type: SpeciesReference

005628
constant: true
value: 0.0
name: a360M0
type: Parameter

897571
kinetic law: 337908
modifier: 337896
product: 337884
fast: false
reversible: false
name: C_ccwtoE_ccw0
type: Reaction

882592
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boundary condition: false
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initial concentration: NaN
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name: A_cw33
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003231
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name: k10_cc
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314278
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species: 878153
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002877
value: 810000.0
name: k10_cw
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899470
kinetic law: 342195
modifier: 342183
modifier: 342171
product: 342159
reactant: 342147
fast: false
reversible: false
name: Start_ccwtoR_ccw8
type: Reaction

877772
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw2
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004177
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005275
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894731
kinetic law: 332608
product: 332595
reactant: 332583
fast: false
reversible: false
name: C_ccw17toA0_ccw
type: Reaction

888811
kinetic law: 320781
product: 320769
reactant: 320757
fast: false
reversible: false
name: R_ccw2toC_ccw2
type: Reaction

331779
stoichiometry: 1.0
species: 879732
type: SpeciesReference

898230
kinetic law: 339506
modifier: 339494
product: 339482
fast: false
reversible: false
name: C_ccwtoE_ccw22
type: Reaction

334432
stoichiometry: 1.0
species: 881192
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899930
kinetic law: 343583
modifier: 343571
modifier: 343559
product: 343547
reactant: 343535
fast: false
reversible: false
name: Start_cwtoR_cw20
type: Reaction

879052
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
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name: R_ccw34
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882852
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
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name: A_ccw39
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004351
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882392
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boundary condition: false
has only substance units: false
initial concentration: NaN
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name: A_cw28
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319492
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species: 878832
type: SpeciesReference

897570
kinetic law: 337872
modifier: 337860
product: 337848
fast: false
reversible: false
name: C_cwtoE_cw0
type: Reaction

004576
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name: ks_cw
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002889
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name: k10_cw
type: LocalParameter

336330
stoichiometry: 1.0
species: 882272
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323221
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species: 879132
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325779
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335712
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species: 881932
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321240
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species: 879832
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326072
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species: 880392
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333066
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species: 881272
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004819
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341551
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species: 877832
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883332
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boundary condition: false
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initial concentration: NaN
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name: E_ccw6
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329932
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species: 880512
type: SpeciesReference

003342
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name: R_cc
type: LocalParameter

333704
stoichiometry: 1.0
species: 880792
type: SpeciesReference

326559
stoichiometry: 1.0
species: 880592
type: SpeciesReference

002886
value: 0.6
name: R_cc
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343001
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species: 878292
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879652
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
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name: C_ccw4
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327929
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species: 881192
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890991
kinetic law: 325039
modifier: 325027
product: 325015
reactant: 325002
fast: false
reversible: false
name: C_cw12ass
type: Reaction

005329
value: 2.48
name: kstop_cc
type: LocalParameter

316808
stoichiometry: 1.0
species: 879232
type: SpeciesReference

342267
stoichiometry: 1.0
species: 884892
type: SpeciesReference

004465
value: 7.0
name: ks_cc
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336625
stoichiometry: 1.0
species: 882432
type: SpeciesReference

321917
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species: 878412
type: SpeciesReference

886272
kinetic law: 315237
modifier: 315225
product: 315213
reactant: 315201
fast: false
reversible: false
name: R_ccw21ass
type: Reaction

889571
kinetic law: 322157
product: 322145
reactant: 322133
fast: false
reversible: false
name: R_ccw21toC_ccw21
type: Reaction

002874
value: 0.6
name: R_cc
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884232
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0307197516454501
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name: E_cw29
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320481
stoichiometry: 1.0
species: 879372
type: SpeciesReference

005541
constant: true
value: 2.07E-9
name: k20_cw
type: Parameter

344198
stoichiometry: 1.0
species: 884892
type: SpeciesReference

005272
value: 2.48
name: kstop_cw
type: LocalParameter

334371
stoichiometry: 1.0
species: 881272
type: SpeciesReference

887731
kinetic law: 318818
product: 318805
reactant: 318793
fast: false
reversible: false
name: R_ccw20diss
type: Reaction

322145
stoichiometry: 1.0
species: 880332
type: SpeciesReference

333282
stoichiometry: 1.0
species: 881272
type: SpeciesReference

322253
stoichiometry: 1.0
species: 880392
type: SpeciesReference

005544
constant: true
value: 0.6
name: C_cw
type: Parameter

898010
kinetic law: 339109
modifier: 339097
product: 339085
fast: false
reversible: false
name: C_cwtoE_cw17
type: Reaction

321132
stoichiometry: 1.0
species: 879772
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886412
kinetic law: 315576
modifier: 315564
product: 315552
reactant: 315540
fast: false
reversible: false
name: R_cw25ass
type: Reaction

326182
stoichiometry: 1.0
species: 880472
type: SpeciesReference

878052
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw9
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318515
stoichiometry: 1.0
species: 878292
type: SpeciesReference

883752
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.18345513147593E-6
in compartment: 877675
name: E_cw17
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881032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw39
type: Species

004243
value: 0.6
name: C_cw
type: LocalParameter

894211
kinetic law: 331658
product: 331646
reactant: 331633
fast: false
reversible: false
name: C_ccw4toA0_ccw
type: Reaction

895911
kinetic law: 334744
product: 334732
reactant: 334720
fast: false
reversible: false
name: Aconfchange_cw2
type: Reaction

897771
kinetic law: 338639
modifier: 338626
product: 338614
fast: false
reversible: false
name: C_ccwtoE_ccw10
type: Reaction

003835
value: 0.03338
name: kdissC_cc
type: LocalParameter

899690
kinetic law: 342857
modifier: 342845
modifier: 342833
product: 342821
reactant: 342809
fast: false
reversible: false
name: Start_cwtoR_cw14
type: Reaction

893371
kinetic law: 330136
product: 330124
reactant: 330112
fast: false
reversible: false
name: C_ccw28diss
type: Reaction

881832
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw14
type: Species

005320
value: 2.48
name: kstop_cw
type: LocalParameter

002934
value: 0.6
name: R_cc
type: LocalParameter

881772
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_ccw12
type: Species

004021
value: 0.6
name: C_cc
type: LocalParameter

003550
value: 0.1177
name: kassC_cw
type: LocalParameter

344801
stoichiometry: 1.0
species: 884892
type: SpeciesReference

329028
stoichiometry: 1.0
species: 879972
type: SpeciesReference

340207
stoichiometry: 1.0
species: 884372
type: SpeciesReference

334080
stoichiometry: 1.0
species: 881272
type: SpeciesReference

897770
kinetic law: 338602
modifier: 338589
product: 338577
fast: false
reversible: false
name: C_cwtoE_cw10
type: Reaction

003234
value: 0.6
name: R_cc
type: LocalParameter

892911
kinetic law: 329300
product: 329288
reactant: 329276
fast: false
reversible: false
name: C_cw17diss
type: Reaction

315648
stoichiometry: 1.0
species: 878752
type: SpeciesReference

002523
value: 0.5341
name: kassR_cw
type: LocalParameter

342688
stoichiometry: 1.0
species: 884872
type: SpeciesReference

897830
kinetic law: 338783
modifier: 338771
product: 338759
fast: false
reversible: false
name: C_ccwtoE_ccw12
type: Reaction

883272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 7.63993708305633E-22
in compartment: 877675
name: E_cw5
type: Species

338358
stoichiometry: 1.0
species: 883352
type: SpeciesReference

340825
stoichiometry: 1.0
species: 884712
type: SpeciesReference

334792
stoichiometry: 1.0
species: 881392
type: SpeciesReference

003838
value: 0.03338
name: kdissC_cw
type: LocalParameter

319557
stoichiometry: 1.0
species: 878912
type: SpeciesReference

892111
kinetic law: 327761
modifier: 327749
product: 327736
reactant: 327723
fast: false
reversible: false
name: C_cw40ass
type: Reaction

878372
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_ccw17
type: Species

002871
value: 810000.0
name: k10_cc
type: LocalParameter

004468
value: 7.0
name: ks_cw
type: LocalParameter

883652
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 2.75423207436283E-11
in compartment: 877675
name: E_ccw14
type: Species

002526
value: 0.5341
name: kassR_cc
type: LocalParameter

004573
value: 7.0
name: ks_cc
type: LocalParameter

003982
value: 2.07E-9
name: k20_cc
type: LocalParameter

899610
kinetic law: 342616
modifier: 342604
modifier: 342592
product: 342580
reactant: 342568
fast: false
reversible: false
name: Start_cwtoR_cw12
type: Reaction

878752
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_cw27
type: Species

886612
kinetic law: 316059
modifier: 316047
product: 316035
reactant: 316023
fast: false
reversible: false
name: R_cw30ass
type: Reaction

332559
stoichiometry: 1.0
species: 881272
type: SpeciesReference

343061
stoichiometry: 1.0
species: 878312
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328015
stoichiometry: 1.0
species: 881192
type: SpeciesReference

899070
kinetic law: 341032
modifier: 341020
product: 341008
fast: false
reversible: false
name: C_ccwtoE_ccw43
type: Reaction

002883
value: 810000.0
name: k10_cc
type: LocalParameter

886492
kinetic law: 315768
modifier: 315756
product: 315744
reactant: 315732
fast: false
reversible: false
name: R_cw27ass
type: Reaction

004501
value: 7.0
name: ks_cc
type: LocalParameter

895991
kinetic law: 334888
product: 334876
reactant: 334864
fast: false
reversible: false
name: Aconfchange_cw4
type: Reaction

002931
value: 810000.0
name: k10_cc
type: LocalParameter

004240
value: 2.07E-9
name: k20_cw
type: LocalParameter

342327
stoichiometry: 1.0
species: 884872
type: SpeciesReference

318407
stoichiometry: 1.0
species: 878232
type: SpeciesReference

005323
value: 2.48
name: kstop_cc
type: LocalParameter

313795
stoichiometry: 1.0
species: 877972
type: SpeciesReference

005122
value: 2.07E-9
name: k20_cw
type: LocalParameter

891371
kinetic law: 325961
modifier: 325949
product: 325937
reactant: 325925
fast: false
reversible: false
name: C_ccw21ass
type: Reaction

878412
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: R_ccw18
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899510
kinetic law: 342315
modifier: 342303
modifier: 342291
product: 342279
reactant: 342267
fast: false
reversible: false
name: Start_ccwtoR_ccw9
type: Reaction

330888
stoichiometry: 1.0
species: 880992
type: SpeciesReference

002529
value: 0.5341
name: kassR_cw
type: LocalParameter

891431
kinetic law: 326108
modifier: 326096
product: 326084
reactant: 326072
fast: false
reversible: false
name: C_cw23ass
type: Reaction

344090
stoichiometry: 1.0
species: 878652
type: SpeciesReference

339518
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species: 883992
type: SpeciesReference

002880
value: 0.6
name: R_cw
type: LocalParameter

882172
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_ccw22
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882632
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boundary condition: false
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initial concentration: NaN
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in compartment: 877675
name: A_cw34
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336407
stoichiometry: 1.0
species: 882312
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003553
value: 0.1177
name: kassC_cc
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329178
stoichiometry: 1.0
species: 880052
type: SpeciesReference

335020
stoichiometry: 1.0
species: 881552
type: SpeciesReference

319644
stoichiometry: 1.0
species: 878912
type: SpeciesReference

002724
value: 0.9314
name: kdissR_cc
type: LocalParameter

004504
value: 7.0
name: ks_cw
type: LocalParameter

320553
stoichiometry: 1.0
species: 879412
type: SpeciesReference

880192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_cw18
type: Species

005547
constant: true
value: 7.0
name: ks_cw
type: Parameter

343789
stoichiometry: 1.0
species: 878552
type: SpeciesReference

324954
stoichiometry: 1.0
species: 879932
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326897
stoichiometry: 1.0
species: 880732
type: SpeciesReference

879472
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
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name: C_cw0
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316507
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species: 879072
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315588
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species: 878692
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895891
kinetic law: 334708
product: 334696
reactant: 334684
fast: false
reversible: false
name: Aconfchange_ccw1
type: Reaction

004246
value: 2.07E-9
name: k20_cc
type: LocalParameter

002937
value: 810000.0
name: k10_cw
type: LocalParameter

004507
value: 7.0
name: ks_cc
type: LocalParameter

331068
stoichiometry: 1.0
species: 881092
type: SpeciesReference

317570
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species: 877792
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330912
stoichiometry: 1.0
species: 881052
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003237
value: 810000.0
name: k10_cw
type: LocalParameter

320408
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species: 879332
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342036
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species: 877992
type: SpeciesReference

889791
kinetic law: 322555
product: 322543
reactant: 322531
fast: false
reversible: false
name: R_cw27toC_cw27
type: Reaction

326220
stoichiometry: 1.0
species: 880452
type: SpeciesReference

003760
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name: kdissC_cw
type: LocalParameter

322362
stoichiometry: 1.0
species: 880452
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333922
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species: 880912
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343849
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species: 878572
type: SpeciesReference

882032
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boundary condition: false
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initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw19
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003832
value: 0.03338
name: kdissC_cw
type: LocalParameter

004570
value: 7.0
name: ks_cw
type: LocalParameter

003985
value: 0.6
name: C_cc
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885532
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modifier: 313434
product: 313421
reactant: 313409
fast: false
reversible: false
name: R_cw3ass
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341299
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species: 884892
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002721
value: 0.9314
name: kdissR_cw
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004357
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name: C_cc
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316893
stoichiometry: 1.0
species: 879232
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343414
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species: 884872
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003568
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name: kassC_cw
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885552
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modifier: 313482
product: 313470
reactant: 313458
fast: false
reversible: false
name: R_ccw3ass
type: Reaction

004945
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name: C_cw
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337920
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species: 883112
type: SpeciesReference

003751
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name: kdissC_cc
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003685
value: 0.03338
name: kdissC_cc
type: LocalParameter

896671
kinetic law: 336123
product: 336111
reactant: 336099
fast: false
reversible: false
name: Aconfchange_cw21
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003228
value: 0.6
name: R_cw
type: LocalParameter

004684
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name: kstop_cw
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004003
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name: C_cw
type: LocalParameter

326280
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species: 880512
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005053
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name: C_cw
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887911
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product: 319132
reactant: 319120
fast: false
reversible: false
name: R_cw25diss
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003607
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name: kassC_cc
type: LocalParameter

892331
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product: 328231
reactant: 328219
fast: false
reversible: false
name: C_ccw2diss
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332765
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species: 880272
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005101
value: 0.6
name: C_cw
type: LocalParameter

331309
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species: 879472
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327295
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species: 880932
type: SpeciesReference

002373
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name: kassR_cw
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893171
kinetic law: 329773
product: 329761
reactant: 329749
fast: false
reversible: false
name: C_ccw23diss
type: Reaction

002676
value: 0.9314
name: kdissR_cc
type: LocalParameter

890091
kinetic law: 323101
product: 323088
reactant: 323076
fast: false
reversible: false
name: R_ccw34toC_ccw34
type: Reaction

002703
value: 0.9314
name: kdissR_cw
type: LocalParameter

888331
kinetic law: 319910
product: 319898
reactant: 319886
fast: false
reversible: false
name: R_ccw35diss
type: Reaction

897111
kinetic law: 336930
product: 336918
reactant: 336906
fast: false
reversible: false
name: Aconfchange_cw32
type: Reaction

002376
value: 0.5341
name: kassR_cc
type: LocalParameter

003120
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name: R_cw
type: LocalParameter

003604
value: 0.1177
name: kassC_cw
type: LocalParameter

318032
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species: 878092
type: SpeciesReference

004720
value: 2.07E-9
name: k20_cc
type: LocalParameter

002679
value: 0.9314
name: kdissR_cw
type: LocalParameter

879492
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_ccw0
type: Species

890791
kinetic law: 324557
modifier: 324545
product: 324533
reactant: 324520
fast: false
reversible: false
name: C_cw7ass
type: Reaction

341660
stoichiometry: 1.0
species: 884892
type: SpeciesReference

003015
value: 810000.0
name: k10_cc
type: LocalParameter

894431
kinetic law: 332057
product: 332045
reactant: 332032
fast: false
reversible: false
name: C_cw10toA0_cw
type: Reaction

323905
stoichiometry: 1.0
species: 879532
type: SpeciesReference

346635
stoichiometry: 1.0
species: 884992
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005125
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341539
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345121
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880172
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002508
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887651
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reversible: false
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003808
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005050
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330524
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004831
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317777
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343109
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004687
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004792
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325307
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329822
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883412
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317825
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323365
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344451
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320252
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889371
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335823
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333572
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332221
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900190
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319084
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002673
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881352
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899050
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313131
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337424
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895211
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004618
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003817
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889171
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895091
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331609
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002706
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333138
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331273
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316699
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324533
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887052
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004261
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895291
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reactant: 333596
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reversible: false
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879912
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005128
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003805
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900490
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326667
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881252
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883972
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887051
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004948
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319348
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893351
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reversible: false
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315841
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325393
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316083
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886792
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890711
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320987
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879992
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003018
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317037
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896031
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reversible: false
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330016
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species: 880512
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003682
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004723
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003754
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884872
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002379
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895011
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335237
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895671
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reactant: 334286
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reversible: false
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003601
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315006
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species: 878452
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003802
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318842
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900110
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modifier: 344102
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328956
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320324
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887311
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886791
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modifier: 316579
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reversible: false
name: R_ccw35ass
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341915
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878032
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name: R_ccw8
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002709
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322580
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species: 880572
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004000
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005104
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004156
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887711
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888111
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333898
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889811
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005467
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005631
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337701
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species: 882992
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004726
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885972
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897271
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328702
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888431
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889011
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reversible: false
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004798
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004612
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883072
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883352
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003129
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328376
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species: 879612
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005107
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005059
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315732
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species: 878752
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004729
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004615
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321639
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species: 880052
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003757
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344938
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891871
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329251
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331381
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888771
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314471
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878852
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345832
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899950
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004372
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885872
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reversible: false
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318951
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002448
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316313
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897071
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317146
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890571
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335189
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335931
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004837
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002859
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900270
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878252
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003126
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899370
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002370
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316941
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894531
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313855
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892551
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005056
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004159
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004006
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334213
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892611
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318261
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313360
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884172
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004681
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005634
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002442
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341008
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004480
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336699
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337014
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003012
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004942
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891751
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341117
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333464
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004009
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004795
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900650
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323004
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003339
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004834
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002445
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336111
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332657
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892051
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334153
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321024
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005464
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329713
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327585
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879272
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898870
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323088
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003123
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318188
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887271
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339954
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003454
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315213
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885652
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004366
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890151
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332921
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329567
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005470
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894811
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002868
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003979
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345241
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318625
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337352
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003333
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323438
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330451
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897411
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322061
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320829
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889671
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888051
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321481
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331164
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002928
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345349
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318104
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315152
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005314
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337062
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003336
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897611
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883132
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330984
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003976
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318733
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895771
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897491
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320613
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880532
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327149
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316120
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321784
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342941
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321857
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882512
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004471
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003457
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005637
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878472
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878532
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004162
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005473
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322750
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891491
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324050
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321712
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894891
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880252
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896511
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333716
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003330
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002898
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343354
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337232
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321517
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329944
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005317
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878632
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899730
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335333
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328159
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879332
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881632
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897610
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883532
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003451
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004477
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326120
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002862
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321929
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336613
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888891
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333680
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891531
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332438
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878312
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005284
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893791
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reversible: false
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329677
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002865
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884392
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883292
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333825
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004474
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893711
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reversible: false
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335663
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342339
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004165
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005287
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334444
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species: 881272
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004588
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898130
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883872
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895571
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882272
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004363
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324183
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890891
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893431
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335700
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881972
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889911
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346511
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880892
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name: C_ccw35
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003826
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335442
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species: 881752
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002514
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004585
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890211
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reactant: 323293
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reversible: false
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005281
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898650
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889451
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reversible: false
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003970
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320769
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879192
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327821
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885112
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879772
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889711
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887431
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product: 318261
reactant: 318249
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reversible: false
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003814
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892991
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332547
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894291
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reactant: 331779
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004252
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341431
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897970
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330741
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species: 880912
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002895
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002592
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320080
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species: 879152
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323161
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326170
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005532
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893651
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reactant: 330620
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reversible: false
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321120
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880472
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346598
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339157
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004255
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895351
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product: 333716
reactant: 333704
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reversible: false
name: C_cw33toA0_cw
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002670
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895811
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product: 334552
reactant: 334540
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reversible: false
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003823
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882732
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896931
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329786
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002922
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885192
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891171
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337124
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900750
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315636
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003811
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002511
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898350
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321409
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885492
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885772
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003562
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899590
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882412
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003222
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331056
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005538
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336797
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330924
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species: 881012
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005110
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002925
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880512
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334840
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886632
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002595
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896831
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326232
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003688
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884652
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003225
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892271
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333934
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321590
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877992
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879112
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886572
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005131
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338723
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331489
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004369
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343426
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329459
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343291
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004582
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003820
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003973
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898570
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337172
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002517
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345723
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314711
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881992
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005134
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005311
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322640
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002712
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002892
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331996
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900970
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003565
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884592
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882492
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320541
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335551
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005535
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345000
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332008
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323989
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326800
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330233
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336553
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333608
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329312
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004258
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896451
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002598
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330876
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330160
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328255
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316071
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888951
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337848
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004678
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886072
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884732
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884032
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321881
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341903
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002967
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333318
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004036
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328799
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346196
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002367
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881112
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003742
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318830
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004735
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335225
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003637
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317001
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328920
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898930
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878132
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334299
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333500
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892691
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891991
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878772
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332909
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322616
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895151
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337412
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317377
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339229
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898070
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002685
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890451
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328847
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004099
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340027
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891011
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003075
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322908
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332885
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002964
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004522
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326462
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878992
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005137
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888631
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331429
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003297
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002961
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885732
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002364
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336256
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326316
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896991
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003132
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003072
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004732
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318044
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317995
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320288
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332161
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330512
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002589
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882652
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003219
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329858
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895311
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004675
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005041
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005529
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004039
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321664
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344030
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320396
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882952
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884992
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004672
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329907
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891911
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004957
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003216
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337956
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322835
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889951
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882092
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892471
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320974
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886652
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317098
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002739
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325002
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002361
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002688
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880032
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880712
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881412
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313698
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004951
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336147
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895531
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332993
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334068
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339590
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314903
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886812
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892731
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003424
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887191
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314290
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318152
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316277
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323076
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002799
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900510
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004093
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003135
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336833
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329053
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331537
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334189
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005419
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313409
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330402
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893291
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319778
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003138
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004090
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324761
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002847
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332341
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886112
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887111
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340099
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885672
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004954
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341780
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004801
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002478
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896551
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337026
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003631
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313372
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899230
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336687
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897331
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881492
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894671
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891571
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344391
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005245
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899310
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330729
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341419
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882912
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315792
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313843
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891631
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005044
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329870
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004147
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886811
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896271
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336039
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319994
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002796
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004885
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325683
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003745
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325925
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882872
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889231
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005047
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328630
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893511
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328364
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004096
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323655
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320866
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889091
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879592
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313168
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004384
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335116
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318987
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004804
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887791
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327331
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898210
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319204
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314483
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877792
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315938
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314627
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888091
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338614
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003634
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003427
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004381
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313276
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340135
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005248
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891231
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321300
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003748
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004144
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887891
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004882
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893071
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890671
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893211
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002793
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004738
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344511
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333885
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893591
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328738
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339373
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879852
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005251
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005038
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004153
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892871
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896491
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335675
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881572
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004888
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318697
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900050
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885892
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884412
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005604
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879232
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002472
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002853
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005410
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881852
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335736
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321264
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899110
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005308
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886332
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modifier: 315370
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reversible: false
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315407
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004198
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897790
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reversible: false
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004375
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324195
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species: 879652
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003967
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895471
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329640
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331755
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897810
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reversible: false
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005607
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328147
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898430
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modifier: 339857
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reversible: false
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005413
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327198
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332122
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005305
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892131
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reversible: false
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325454
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337244
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004195
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321529
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340786
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894171
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reversible: false
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883672
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886971
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reversible: false
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897811
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modifier: 338735
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reversible: false
name: C_cwtoE_cw12
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896171
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product: 335201
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reversible: false
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334395
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334660
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900690
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reactant: 345832
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reversible: false
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002790
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004441
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341600
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species: 884872
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330620
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878292
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004228
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002850
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895971
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product: 334840
reactant: 334828
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reversible: false
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900890
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modifier: 346475
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reactant: 346439
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reversible: false
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892031
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reversible: false
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321772
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894751
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reactant: 332620
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reversible: false
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899530
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modifier: 342351
product: 342339
reactant: 342327
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reversible: false
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891351
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reversible: false
name: C_cw21ass
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882572
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318769
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899450
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modifier: 342111
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reversible: false
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888271
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reactant: 319778
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reversible: false
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330040
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343657
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316132
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species: 878952
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003964
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315249
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331851
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species: 879772
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896331
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326763
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345603
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322762
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314327
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species: 878172
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004150
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880332
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boundary condition: false
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initial concentration: NaN
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name: C_ccw21
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335527
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species: 881832
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005254
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320649
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species: 877732
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005601
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002856
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330378
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species: 880712
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890331
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reactant: 323510
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reversible: false
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003850
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882372
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initial concentration: NaN
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name: A_ccw27
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324821
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342881
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003421
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879032
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name: R_cw34
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889871
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887571
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322494
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879632
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345301
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species: 879052
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004378
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004225
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882212
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329579
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330488
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319420
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species: 878792
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003853
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005302
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337050
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species: 882632
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005416
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335080
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320142
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885052
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898790
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319048
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316760
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884252
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336356
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338868
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343547
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890291
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314086
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340568
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886292
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318613
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341359
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900810
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reactant: 346196
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reversible: false
name: Start_cwtoR_cw42
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002475
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337388
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species: 882852
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004591
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336468
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894231
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331960
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899670
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003577
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315358
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883732
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327621
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004528
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878072
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886432
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005146
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002505
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877912
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initial concentration: NaN
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319531
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004222
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883252
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002586
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325163
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336589
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895611
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326812
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004447
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324339
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339445
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330269
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002748
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325828
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894971
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893391
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881792
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323583
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327005
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893851
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005523
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890931
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003213
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002583
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329422
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327773
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878352
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890071
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314194
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877852
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name: R_cw4
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005526
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336761
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species: 882472
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003856
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004594
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899090
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003961
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330596
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species: 880832
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896651
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317595
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884512
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002745
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338759
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005143
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321457
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003069
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889391
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897551
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344679
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329798
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895691
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318539
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882152
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name: A_cw22
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002682
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337496
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891411
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880112
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initial concentration: NaN
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name: C_cw16
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005520
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889511
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897550
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879452
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name: R_ccw44
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003574
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331646
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326957
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species: 880792
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003210
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338138
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species: 883232
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003859
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name: kdissC_cc
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880672
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879512
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name: C_cw1
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004045
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002958
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name: R_cc
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318479
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species: 878272
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893131
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reactant: 329677
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reversible: false
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notes: A quantitative model of the switch cycle of an archaeal flagellar motor and its sensory control, Nutsch et al, Biophys. J. 2005 ( 16192281 ) and del Rosario et al, IET Syst. Biol. 2007 ( 17708428 ). This is the non-cyclic model for spontaneous simulations used in creating Figure 5C of del Rosario 2007. The value plotted in the figure is ks*A_43(t)/max(ks*A_43(t)), where ks is a model parameter. In the figure, the asymmetric model with 10% and 50% increase in parameter R_cw are compared with data for spontaneous, repellent and attractant stimuli. There are 5 SBML models provided: spontaneous simulations (all light parameters Iuv, Ibl and Ior are zero) repellent dark (sensor via SRII but with Ibl = 0) repellent light (sensor via SRII) attractant dark (sensor via SRI but with Iuv=Ior=0) attractant light (sensor via SRI) The 5 SBML files are "symmetric" models since the parameters in the clockwise and counter-clockwise directions are equal. For the asymmetric simulations in Figure 5c, parameter R_cw must be increased 10% and 50%. We provide the following Matlab code to plot figure 5c using the Systems Biology Toolbox: ---- begining of Matlab code myodeoptions = odeset('AbsTol', 1e-10, 'RelTol', 1e-8); dark1 = linspace(0, 2, 1000); lighton = linspace(2, 2+0.02, 100); dark2 = linspace(2+0.02, 60, 1000); %for spontaneous, no need to separate since all dark tspan = [dark1,lighton(2:end),dark2(2:end)]; sbmodspont = SBmodel('Nutsch2005_phototaxis_noncyc_spont.xml'); sbmodrepdark = SBmodel('Nutsch2005_phototaxis_noncyc_rep_dark.xml'); sbmodreplight = SBmodel('Nutsch2005_phototaxis_noncyc_rep_light.xml'); sbmodattdark = SBmodel('Nutsch2005_phototaxis_noncyc_att_dark.xml'); sbmodattlight = SBmodel('Nutsch2005_phototaxis_noncyc_att_light.xml'); R_cw_nominal = SBparameters(sbmodspont, 'R_cw'); R_cw_10inc = R_cw_nominal + 0.1*R_cw_nominal; R_cw_50inc = R_cw_nominal + 0.5*R_cw_nominal; sbmodspont10 = SBparameters(sbmodspont, 'R_cw', R_cw_10inc); sbmodspont50 = SBparameters(sbmodspon…
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fast: false
reversible: false
name: C_cw1ass
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003147
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003436
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316265
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899970
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product: 343669
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reversible: false
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003739
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003081
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005407
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880612
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340243
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336845
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334177
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321048
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005488
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002838
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003439
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313264
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894511
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885692
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reversible: false
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881332
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004393
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003622
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317232
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316857
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330693
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334828
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899390
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343909
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322543
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004132
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346014
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321312
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345482
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886192
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reversible: false
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003736
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886991
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884152
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004894
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004303
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328726
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900470
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892571
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887031
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reactant: 317450
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reversible: false
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004897
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894011
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fast: false
reversible: false
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325791
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325695
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324665
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325937
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003733
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336027
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330148
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323667
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900670
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886772
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891771
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005035
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322567
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345530
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337726
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335008
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004396
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895031
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reactant: 333126
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318975
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879252
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884852
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004960
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886771
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reversible: false
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315926
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314615
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004816
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003949
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320006
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327343
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888831
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005401
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886212
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reversible: false
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883092
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005619
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881952
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899190
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325442
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004183
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897890
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reversible: false
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003502
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335748
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species: 881952
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342207
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species: 884872
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332414
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322133
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888711
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003958
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344925
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species: 884892
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889651
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product: 322290
reactant: 322278
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reversible: false
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004309
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name: C_cc
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005029
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889731
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reactant: 322422
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reversible: false
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344210
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321192
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005260
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003580
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885812
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modifier: 314110
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reactant: 314086
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reversible: false
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897431
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005491
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879792
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name: C_cw8
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342279
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004453
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319705
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341612
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880932
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331104
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893491
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336990
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005026
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880552
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344439
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879712
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name: C_cw6
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005263
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004141
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344017
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species: 884872
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002841
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323293
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species: 879172
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005616
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341491
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314242
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895751
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002460
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318685
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888791
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004450
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313614
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328690
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883152
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333054
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004807
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340460
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880232
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332148
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331743
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329652
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004306
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327917
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898830
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878492
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900730
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315503
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004387
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003955
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004186
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005494
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878612
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003841
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336369
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896851
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896531
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324435
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004237
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884632
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879352
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003430
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338977
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886552
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878332
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335092
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346087
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320154
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334972
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323854
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005404
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317450
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891551
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333162
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337376
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323414
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330475
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002463
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314098
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883512
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893731
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004189
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343669
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003952
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896791
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318757
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326751
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318805
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884372
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328509
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314339
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893411
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005497
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005266
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332083
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331864
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882292
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338286
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003433
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878692
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317522
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340604
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002844
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005613
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898150
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890171
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329434
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898670
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002571
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003294
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327785
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890231
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321989
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003201
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337592
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005514
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336773
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004519
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002949
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889431
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331032
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002733
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882792
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326268
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003844
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323305
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330584
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887451
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fast: false
reversible: false
name: R_ccw13diss
type: Reaction

322350
stoichiometry: 1.0
species: 878652
type: SpeciesReference

005155
value: 0.6
name: C_cc
type: LocalParameter

327633
stoichiometry: 1.0
species: 881072
type: SpeciesReference

319632
stoichiometry: 1.0
species: 878952
type: SpeciesReference

318321
stoichiometry: 1.0
species: 878232
type: SpeciesReference

885172
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 1.0
in compartment: 877675
name: Esum_cw
type: Species

004516
value: 7.0
name: ks_cw
type: LocalParameter

337628
stoichiometry: 1.0
species: 882952
type: SpeciesReference

895331
kinetic law: 333692
product: 333680
reactant: 333668
fast: false
reversible: false
name: C_ccw32toA0_ccw
type: Reaction

003589
value: 0.1177
name: kassC_cc
type: LocalParameter

882712
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw36
type: Species

331972
stoichiometry: 1.0
species: 881272
type: SpeciesReference

330851
stoichiometry: 1.0
species: 880972
type: SpeciesReference

337196
stoichiometry: 1.0
species: 882712
type: SpeciesReference

329166
stoichiometry: 1.0
species: 880092
type: SpeciesReference

005158
value: 2.07E-9
name: k20_cw
type: LocalParameter

880452
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: C_ccw24
type: Species

336577
stoichiometry: 1.0
species: 882372
type: SpeciesReference

004459
value: 7.0
name: ks_cc
type: LocalParameter

324327
stoichiometry: 1.0
species: 879672
type: SpeciesReference

882432
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 877675
name: A_cw29
type: Species