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type: LocalParameter

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name: LRRGSmGaGTPEffectorOFF hydrolyzes GTP
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type: LocalParameter

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persistant: true
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type: Trigger

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name: 1/hr
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type: LocalParameter

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BIOMD0000000479
is: MODEL1305280000
length unit: length
creator:
  ORG:
    orgname: EMBL-EBI
  n:
    given: Vijayalakshmi
    family: Chelliah
area units: area
is described by: http://identifiers.org/pubmed/23900842
curated: true
created:
  W3 CDTF: Fri Sep 13 13:39:39 BST 2013
type: SBMLModel
creator:
  ORG:
    orgname: University of Warwick
  n:
    given: Manuel
    family: Esparza-Franco
modified:
  W3 CDTF: Wed Oct 09 14:28:27 BST 2013
is version of: GO:0043087
notes: This is a model from the article: Compartmentalized regulation of the GTPase-cycle by RGS. Croft W, Hill C, McCann E, Bond M, Esparza-Franco M A, Bennett J, Rand D, Davey J, Ladds G. 2013,submitted. To reproduce dose-response plots in the publication, the model is simulated with 12 different ligand concentrations (see parameter Ligand_conc). For each ligand concentration, a single value corresponding to total amount of output must be obtained, by calculating the area under the curve of the trajectory of species z3, from time=0 to time=30. These total output values are then used to build a dose-response plot (authors used GraphPad Prism). Mutant strains are simulated with alternative parameter values or initial conditions specified in the Supplementary Material.
time units: metaid_0000039
creator:
  ORG:
    orgname: University of Warwick
  n:
    given: Wayne
    family: Croft
occurs in: http://identifiers.org/taxonomy/4932
name: Croft2013 - GPCR-RGS interaction that compartmentalizes RGS activity

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name: nM
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name: LRGabg
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name: RGSmGaGTP
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_304bd4e6_3eff_4295_81ae_3d3f792a4376
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: z3
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_1b94c956_3391_4420_9197_78cd2a0da37e
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/BIOMD0000000479#_54403e85_8e3b_411d_b860_acaf783ddf93
value: 0.5
name: k31
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#c49d365a_5e5e_43b5_a011_112efdf4eaca
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_26e29572_846e_4528_bcf7_f67f310a6033
notes: Dose-response plots use: 0.1, 1, 3.16228, 10, 31.6228, 100, 316.228, 1000, 3162.28, 10000, 31622.8, 100000
constant: true
value: 0.1
name: Ligand_conc
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000479#a9f6ded1_eaf4_49ed_be0a_bce7b9570a6f
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_19e0a7ca_267c_4f56_ae82_96880d799f10
constant: false
boundary condition: false
has only substance units: false
initial concentration: 60.0
initial amount: NaN
name: RGSc
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_5db51d1a_eb99_461b_bdf3_8ef1bf9b36b9
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#e08e1699_3df3_4db6_8f4d_bbf5ee474eaf
value: 1000.0
name: k38
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#a27a787a_a9e6_47bc_9c14_6b285cd7a055
name: hr
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/BIOMD0000000479#e154c312_3483_4c5c_8ba5_e86e93dbc048
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#bb3f0140_c7b2_41a1_8834_ec9efd6531f9
fast: false
reversible: false
name: RGS in cytosol moves to membrane
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#e192f78b_1901_434c_9ad1_f781f0dd99f3
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#deaf6102_467d_409e_9f85_76b91d2513d3
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_3755d5b6_25ad_48b5_91d7_256cbf2a3397
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#cbc5a4de_55a2_4d60_8410_e554d5a68729
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_1863e76d_536a_4dec_ae20_ffb068457bf7
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_650086b9_5b27_4fea_b0c1_c2c305a0c5a5
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: RGSm
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#cf29a3e5_04a6_4bb3_b2dd_5d057b8fea6c
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#d0df6b67_c5be_4bdb_9c1e_13ddf3a67562
value: 0.1
name: k20
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#_17a0a68b_b7e5_41f3_aa14_0efdf56530b7
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_445a59ec_3c3d_479c_be08_e69cf65560cc
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: GaGDPP
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_4c0020f6_e94d_43ee_bd98_cfe8fdaaad35
value: 10.0
name: k40
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#f272bab2_c1f7_4c50_ab72_b662a199111f
name: Gprotein activation by LRRGSm
type: Reaction
fast: false
reversible: false

http://identifiers.org/biomodels.db/BIOMD0000000479#_1f14ba90_6c64_4fe2_a52c_2f8b2fe1f1d7
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: RRGSmGabg
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#a4011b80_c527_44ef_bd46_d320afbf9c5b
fast: false
reversible: false
name: Effector turns off
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#c0e411d0_1d5b_48c7_8495_af5ad215666f
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: LRRGSm
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_0eb9517d_4f5f_483e_a075_54751c5c50d9
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_7fafb7d2_3dfc_4199_bdc0_6c1eb928e658
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#b7b97554_ec12_4187_83d4_2fb6446f981d
fast: false
reversible: false
name: Delay 2
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#_04a204d5_2ad0_4a55_a63f_3aae761881f5
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_4e489dac_db6b_4117_9990_aabaa2e07ca8
fast: false
reversible: false
name: LRRGSmGaGTP hydrolyzes GTP
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#e9efc02e_4317_4260_bada_0c63424c977d
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#c55d21db_c5fe_4974_87d4_41ef2f7fe87c
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_5e1a312b_0d87_4344_bfc3_3f5ed8ca0d79
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_1bc8cd95_491d_488f_aea5_de7c2bc05bcc
constant: true
value: 1.5
name: ka
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000479#ab37fd09_be6d_46e6_8dbc_5a35897f56a3
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#a9c818f7_7f64_452b_b951_3779b57bce97
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#f1dbc3d9_733b_4081_93b9_2f80465873d7
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#b4cd1fa8_b50e_404a_9df5_19afcaea5e9b
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: GaGTPEffector
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_1a69dd6e_cab3_4ed3_8d18_05c899d4c4d2
constant: false
boundary condition: false
has only substance units: false
initial concentration: 305.0
initial amount: NaN
name: Effector
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_2fc6f6d5_4360_4eb9_b5c2_f64d5ce43fa2
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_393b6108_63da_484b_b976_fae41c3bbe2e
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_038c9cf9_5368_4c70_a9ed_a6ee21e07f22
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_0a05bb18_d533_4e6d_be0e_016437ebb339
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#dd3b2217_04c4_4f16_a6cc_bdd71a3d4e87
fast: false
reversible: false
name: RRGSmGaGTP hydrolyzes GTP
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#ccb3f138_cba9_4683_b26f_44d43ce0eb6e
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#dbc3a1ed_0bce_4503_bb9d_66c1828b4743
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_7acc7efd_c94e_45cc_a3db_1bfb7d5e1562
fast: false
reversible: false
name: RGSmGaGTP hydrolyzes GTP
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#_0f6fd2d3_1db6_4f64_9597_9046ffeed0c0
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_7e133cc3_6e4a_42e8_91f7_ab503a529356
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_11efcf35_d681_4b64_bd3d_37874b1c4c69
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_9de56aba_d053_46e2_a925_efe719b62606
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: z2
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#f0fa934b_f481_46f3_bfb3_4d6795c527b7
value: 50.0
name: k9
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#bc97f308_5b7c_4675_9d6c_94c804ad324e
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#a788300b_26b5_4728_a7d8_a85dd6e0c0fe
value: 100.0
name: k18
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#ef1929db_dbfa_4275_bad7_898d713c81e7
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: Gabg
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_5e24f579_f49a_40eb_9961_eff62e3db803
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_9adf43fb_21bd_47d8_b888_0f25aa29c6e2
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/BIOMD0000000479#_3f017476_801b_45c4_a620_6822cd2341ad
name: RRGSm-Gprotein association
reversible: false
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000479#dffefe3c_ead4_4385_888c_fcc2f0a88938
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_159342eb_350b_48d9_9824_0cf0e8c87347
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_75d95b78_dcfc_477e_bc63_1bdb738cf8c1
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#cf23fcd5_a158_418b_9b28_eb0a1dd487b2
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#bf9707d6_5b22_411a_b752_b43b2194b4c6
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: LRRGSmGaGTPEffectorOFF
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#_9f8df46f_ad4a_47b7_acef_4ef94ceac0f4
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_647db476_e17e_45d5_9c03_28686602c45b
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#ffa7dcfa_ffd2_480b_828e_f29362b3d3bb
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_97dbebc8_29fc_436f_97ff_f667fcd2e24c
value: 0.0025
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#d5581ff8_f00c_43b5_b5f9_153dbb08c0d9
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_28d9093c_4040_4c02_8104_02ed89734a1e
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_8882c673_7374_4751_8f12_b021807beb5e
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_8ce641be_d9bb_4cc6_8af5_f9812ae4a343
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#d9ff1f8f_ac95_40f1_a9dd_feedc0f83bed
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_48230bd3_e384_44db_bf97_d42c1a2049b6
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_511c40fb_1d12_408b_9f8d_80ec47bf2bdb
value: 0.3
name: k35
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#_5f2bf915_3455_4b5d_8ac2_d12b515e5c6f
type: Reaction
reversible: false
name: LRGabg recruits RGSc to membrane
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000479#_65ef3f04_1af0_47d7_9c22_cfe7eeeb0048
exponent: -1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/BIOMD0000000479#_7beddffc_125f_4e61_9232_9eb3b49c09a5
value: 40.0
name: k11
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#_7cca5f26_bd4d_453c_935e_437094fbd66d
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_2bc5606d_5fc8_4572_8e22_350874c4be30
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

http://identifiers.org/biomodels.db/BIOMD0000000479#_7ce965c1_22e5_43a9_91f4_04e0b58c3a0a
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: RRGSm
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#f0916b69_f1a3_4337_a284_b6ff9ed07b92
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_0b661d93_5e24_483f_9ccd_8d1de348cb43
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#b8b10726_2f21_428a_9209_5395fa619853
fast: false
reversible: false
name: Final output
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#_18f30462_645c_4769_8900_8161943bf4d3
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_3d49bbf6_e436_4a88_b3c9_77ae7794c07a
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_451e2bc6_396e_4e18_ab41_20b09ecfbe5c
reversible: false
type: Reaction
name: Effector-GaGTP association
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000479#a683bbc0_1b01_40b1_a68e_808c6e8fe350
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#a4797be9_0cdb_4fd4_be99_6cd6b6af06ea
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#c853880e_fc75_4cb3_beab_d58ecd96b54b
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_36d86ae3_3280_4c0c_8a0b_fd4368a0fe5d
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_7866f0d8_26ff_4f6f_878b_54c1a3232090
fast: false
reversible: false
name: GaGTPEffectorOFF hydrolyzes GTP
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#c7958856_abd7_4a0f_a778_f8ddd8ba5e4a
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_49ebfd6e_3549_426f_a627_93fd123d82a0
stoichiometry: 1.0
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http://identifiers.org/biomodels.db/BIOMD0000000479#afb0af2a_e2b5_40d3_a9bc_67211176e37d
reversible: false
name: GaGTPEffectorOFF recruits RGS from cytosol
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000479#_15be997d_6a59_4c96_9fa5_5a463db3ff64
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#ec988ed5_6c08_4fc7_ba4d_a499df35320a
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_945d0240_2a66_4358_9be2_f57fc3e6d3fd
type: Reaction
reversible: false
fast: false
name: GaGTP recruits RGSc to membrane

http://identifiers.org/biomodels.db/BIOMD0000000479#_60019822_1780_4963_a1a0_67ed1b3e21b6
fast: false
reversible: false
name: RGS in membrane moves to cytosol
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#_2902c868_a163_4507_b2a8_a00215ecb7be
stoichiometry: 1.0
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http://identifiers.org/biomodels.db/BIOMD0000000479#_451bc047_2b4e_461e_8029_eb9656dfd808
stoichiometry: 1.0
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http://identifiers.org/biomodels.db/BIOMD0000000479#_6ca69dc8_a82b_45ce_ae0a_b0c9bebcc8dd
fast: false
reversible: false
name: Delay 3
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#e43c930b_3185_4438_b8d3_615af6013442
value: 0.1
name: k21
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000479#f198b488_6e47_4def_b5f9_63717702250f
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_18ef07a7_0efe_460d_960e_0b8fcc700baa
fast: false
reversible: false
name: R-RGSm dissociation
type: Reaction

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stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#ac2777d6_583e_4950_a463_458dc0fd4348
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: z1
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000479#b0a1c17c_85c8_48e4_b7be_d346a81ed3b2
value: 0.2
name: k10
type: LocalParameter

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fast: false
reversible: false
name: Gprotein spontaneous activation
type: Reaction

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stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_777afc8b_e07f_4ab6_801c_3be73857b163
type: Reaction
reversible: false
fast: false
name: Gprotein activation by LR

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stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#_59d3bf81_3148_4a2f_b6c0_63a0cba983eb
stoichiometry: 1.0
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constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: RRGSmGaGTP
type: Species

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fast: false
reversible: false
name: LR-RGSm dissociation
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#_03a1548c_e8e2_49f7_bd18_3df5c9a46361
fast: false
reversible: false
name: RGSmGaGTP dissociation
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000479#eeabc557_eb95_4230_bb21_ce0407ad0119
stoichiometry: 1.0
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000479#b781b991_d1a2_4d21_8b18_440d1014be13
stoichiometry: 1.0
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