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stoichiometry: 1.0
species: meta s 1038
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value: 0.0112908713189552
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meta e 0639
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is: P15624
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constant: true

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 0581
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initial amount: NaN
is: CHEBI:57737
boundary condition: false
initial concentration: 0.1
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type: Species
is: C00231
constant: false
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units: dimensionless
value: 1.0
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stoichiometry: 1.0
species: meta s 0456
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units: dimensionless
value: 1.0
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value: 4.0884339927971E-5
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0126
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meta s 0582
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initial amount: NaN
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initial concentration: 0.1
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name: dADP
constant: false
is: SBO:0000247
is: C00206

meta e 0637
type: Species
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initial amount: NaN
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is encoded by: S000004046
constant: true
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initial concentration: 0.001

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units: dimensionless
value: -1.0
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meta s 0434
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is: CHEBI:30616
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name: ATP
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units: dimensionless
value: -1.0
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constant: true
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units: dimensionless
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meta e 0525
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boundary condition: true
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meta e 0638
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boundary condition: true
is: SBO:0000252
initial amount: NaN
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constant: true
type: Species
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is encoded by: S000004048
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initial concentration: 0.001
name: SHM2

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stoichiometry: 1.0
species: meta s 0403
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stoichiometry: 1.0
species: meta s 1107
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constant: true
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units: dimensionless
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stoichiometry: 1.0
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meta s 0764
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constant: false
initial amount: NaN
initial concentration: 0.1

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units: dimensionless
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value: 2.87599469319674
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 1.0
species: meta s 1198
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value: 0.00375691882979276
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units: dimensionless
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meta s 0432
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is: C02984
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units: dimensionless
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units: dimensionless
value: 1.0
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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
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stoichiometry: 1.0
species: meta s 0061
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stoichiometry: 1.0
species: meta s 0633
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value: 0.0112491235594566
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units: dimensionless
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units: dimensionless
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meta s 0586
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is: CHEBI:61404
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type: Species
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initial amount: NaN
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units: dimensionless
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units: dimensionless
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stoichiometry: 0.1854
species: meta s 1607
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units: dimensionless
value: 1.0
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stoichiometry: 1.0
species: meta s 0066
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stoichiometry: 2.0
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units: dimensionless
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value: 0.00625077817220671
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units: dimensionless
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stoichiometry: 1.0
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meta s 0430
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meta s 0209
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type: Species
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constant: false
boundary condition: false
is: C15816
name: 3-dehydro-4-methylzymosterol
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is: CHEBI:50593

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stoichiometry: 1.0
species: meta s 1271
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stoichiometry: 1.0
species: meta s 1620
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stoichiometry: 1.0
species: meta s 0979
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value: 2.04421699980673E-5
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1538
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stoichiometry: 2.0
species: meta s 1322
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constant: true
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meta s 0584
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is: CHEBI:58245
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has only substance units: false
name: dAMP
type: Species
boundary condition: false
is: C00360

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units: dimensionless
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value: 2.93389817698765
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units: dimensionless
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stoichiometry: 1.0
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value: 1.3575612338737E-4
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value: 0.0100308480322675
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stoichiometry: 1.0
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units: dimensionless
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meta s 0589
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meta e 0631
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is: P54113
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constant: true
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is: SBO:0000252
boundary condition: true
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units: dimensionless
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 2.0
species: meta s 1207
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meta s 0587
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type: Species
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boundary condition: false

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units: dimensionless
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stoichiometry: 1.0
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meta r 0711
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species: meta s 1487
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stoichiometry: 1.0
species: meta s 0420
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meta e 0632
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boundary condition: true
type: Species
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is: SBO:0000252
in compartment: meta cell

meta r 0713
is: R00342
fast: false
name: malate dehydrogenase
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type: Reaction
is: SBO:0000176

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stoichiometry: 1.0
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stoichiometry: 1.0
species: meta s 0362
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value: 0.0386660157978829
type: LocalParameter

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name: ILV3
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constant: true

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stoichiometry: 1.0
species: meta s 0404
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constant: true
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stoichiometry: 1.0
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meta e 0633
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boundary condition: true
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constant: true
value: 0.1
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units: dimensionless
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constant: true
value: 0.1
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stoichiometry: 0.1339
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meta s 0211
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constant: true
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meta e 0401
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stoichiometry: 1.0
species: meta s 1487
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constant: true
value: 0.1
type: Parameter

meta r 0080
is: SBO:0000176
name: 5,10-methylenetetrahydrofolate reductase (NADPH)
type: Reaction
fast: false
is: R01224
reversible: true

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value: 0.0174126109617655
type: LocalParameter

meta s 0210
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boundary condition: false
initial concentration: 0.1
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meta e 0973
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is: P32486
is: SBO:0000252
initial concentration: 0.001
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has only substance units: false
boundary condition: true

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units: dimensionless
value: -1.0
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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0434
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units: dimensionless
value: -1.0
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units: dimensionless
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units: dimensionless
value: -1.0
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units: dimensionless
value: 1.0
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stoichiometry: 1.0
species: meta s 0529
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constant: true
value: 0.1
type: Parameter

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constant: true
value: 0.1
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value: 0.0386660157978829
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0529
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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 2.0
species: meta s 0394
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units: dimensionless
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constant: true
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constant: true
value: 0.1
type: Parameter

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units: dimensionless
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is: SBO:0000176
name: C-5 sterol desaturase
type: Reaction
reversible: true

meta extracellular
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is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
type: Compartment

meta r 1026
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fast: false
is: R00530
type: Reaction
is: SBO:0000176
reversible: true

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constant: true
value: 0.1
type: Parameter

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constant: true
value: 0.1
type: Parameter

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value: 1.09303224869629E-4
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_7bc958a4_7601_4853_8366_014697abfca2
constant: true
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meta e 0970
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initial concentration: 0.001
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is encoded by: sce:YPR145W

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stoichiometry: 1.0
species: meta s 1073
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_391daf29_c6e5_4cf2_9bed_9cde91eb4633
value: 4.80554664340808E-4
type: LocalParameter

meta e 0405
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name: ENO1
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boundary condition: true
type: Species
initial amount: NaN
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meta e 0852
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is encoded by: sce:YOR095C
is encoded by: S000005621
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is: SBO:0000252
boundary condition: true
type: Species
constant: true
name: RKI1
initial amount: NaN
is: Q12189

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stoichiometry: 1.0
species: meta s 0619
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value: 1.09303224869629E-4
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0633
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meta e 0747
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boundary condition: true
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constant: true
initial amount: NaN
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is: P24521
is encoded by: sce:YMR220W
in compartment: meta cell
initial concentration: 0.001

http://identifiers.org/biomodels.db/BIOMD0000000471#d21fd4fe_25c9_4ad5_a279_d420058dbc34
value: 2.58760203874159E-4
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0475
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meta e 0851
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boundary condition: true
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type: Species
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is encoded by: S000005607
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initial amount: NaN
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constant: true

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units: dimensionless
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stoichiometry: 1.0
species: meta s 0301
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stoichiometry: 1.0
species: meta s 0146
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stoichiometry: 1.0
species: meta s 1342
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stoichiometry: 1.0
species: meta s 1620
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meta e 0746
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is encoded by: S000004830
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is: SBO:0000252
boundary condition: true
initial amount: NaN
type: Species

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units: dimensionless
value: 1.0
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value: 1.46007394609031
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meta e 0850
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is: P06785
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is: SBO:0000252
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constant: true
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initial concentration: 0.001
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000471#_681edcb2_9b49_483f_b49f_f321e25bd982
value: 2.56634863390825E-4
type: LocalParameter

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units: dimensionless
value: 1.0
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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0100
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constant: true
boundary condition: true
initial concentration: 0.001
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type: Species
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is encoded by: sce:YCL009C
in compartment: meta cell
name: ILV6
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_34351bfa_d836_4339_8a27_01706ce91e0e
stoichiometry: 1.0
species: meta s 1101
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
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meta e 0745
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initial amount: NaN
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boundary condition: true
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type: Species
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constant: true
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name: ERG12
initial concentration: 0.001

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units: dimensionless
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stoichiometry: 1.0
species: meta s 1207
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meta e 0743
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boundary condition: true
initial amount: NaN
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type: Species
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is encoded by: S000004818

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stoichiometry: 1.0
species: meta s 0747
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units: dimensionless
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http://identifiers.org/biomodels.db/BIOMD0000000471#_3473e3de_1d18_4c4d_aabd_7af079132e23
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type: LocalParameter

meta e 0409
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meta e 0744
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constant: true
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boundary condition: true
in compartment: meta cell
name: HFA1
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stoichiometry: 1.0
species: meta s 1238
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meta s 0218
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boundary condition: false
initial concentration: 0.1
initial amount: NaN
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is: SBO:0000247
is: C00356
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is: CHEBI:11814

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value: 0.0114540671060863
type: LocalParameter

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stoichiometry: 2.0
species: meta s 1207
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meta s 0362
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initial concentration: 0.1
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meta e 0255
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type: Species

meta e 0742
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in compartment: meta cell

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value: 5.30955595806181E-4
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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units: dimensionless
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value: 3.36354094523684E-6
type: LocalParameter

meta e 0101
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stoichiometry: 1.0
species: meta s 0434
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meta e 0741
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initial amount: NaN
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type: Species
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is: P49095
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initial concentration: 0.001
is encoded by: S000004801
boundary condition: true

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stoichiometry: 2.0
species: meta s 1198
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stoichiometry: 1.0
species: meta s 0394
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

meta e 0855
constant: true
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boundary condition: true
type: Species
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initial concentration: 0.001
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is encoded by: sce:YOR108W
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initial amount: NaN

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0195
is: R00836
reversible: true
is: SBO:0000176
type: Reaction
fast: false
name: alpha,alpha-trehalose-phosphate synthase (UDP-forming)

meta s 0754
initial concentration: 0.1
is: C00127
boundary condition: false
is: SBO:0000247
type: Species
is: CHEBI:58297
name: glutathione disulfide
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constant: false
has only substance units: false
initial amount: NaN

meta e 0104
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constant: true
type: Species
is: SBO:0000252
initial amount: NaN
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name: GRX1
in compartment: meta cell
is encoded by: sce:YCL035C
initial concentration: 0.001

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value: 0.00217467874388578
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0445
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0940
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0423
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 6.0
species: meta s 1212
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0019
type: SpeciesReference

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value: 4.0884339927971E-5
type: LocalParameter

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is: SBO:0000252
in compartment: meta cell
constant: true
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is encoded by: sce:YCL030C
initial amount: NaN
boundary condition: true
is: P00815
name: HIS4

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 0367
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initial amount: NaN
constant: false
has only substance units: false
type: Species
initial concentration: 0.1
is: SBO:0000247
name: acetoacetyl-CoA
in compartment: meta cell
is: C00332
boundary condition: false

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stoichiometry: 1.0
species: meta s 0529
type: SpeciesReference

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type: Reaction
is: SBO:0000185
fast: false
reversible: true
name: phosphate transport

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stoichiometry: 1.0
species: meta s 1377
type: SpeciesReference

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value: 0.00209877372781628
type: LocalParameter

meta s 0428
initial amount: NaN
name: Arg-tRNA(Arg)
in compartment: meta cell
type: Species
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is: SBO:0000247
initial concentration: 0.1
boundary condition: false
constant: false
is: C02163
has only substance units: false

meta e 0978
initial amount: NaN
name: QCR2
initial concentration: 0.001
is encoded by: S000006395
constant: true
is: SBO:0000252
in compartment: meta cell
is encoded by: sce:YPR191W
is: P07257
has only substance units: false
type: Species
boundary condition: true

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units: dimensionless
value: 3.9E-4
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 1.02210849110579E-5
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 0.00209877372752306
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0423
type: SpeciesReference

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value: 0.00726411015276989
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

meta s 0757
constant: false
is: CHEBI:29156
initial concentration: 0.1
type: Species
initial amount: NaN
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is: C02412
is: SBO:0000247
boundary condition: false
in compartment: meta cell
has only substance units: false

meta s 0427
is: CHEBI:16567
initial amount: NaN
type: Species
in compartment: meta cell
boundary condition: false
name: anthranilate
is: C00108
initial concentration: 0.1
is: SBO:0000247
has only substance units: false
constant: false

meta e 0107
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type: Species
in compartment: meta cell
is encoded by: sce:YCL050C
initial amount: NaN
initial concentration: 0.001
name: APA1
has only substance units: false
is: P16550
is: SBO:0000252
constant: true
boundary condition: true

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0764
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0250
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initial concentration: 0.001
is: SBO:0000252
boundary condition: true
is encoded by: S000000750
type: Species
has only substance units: false
constant: true
name: RIP1
is encoded by: sce:YEL024W
is: P08067
initial amount: NaN

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reversible: true
type: Reaction
fast: false
is: SBO:0000176
name: C-22 sterol desaturase (NADP)

meta e 0976
type: Species
name: DPM1
is encoded by: sce:YPR183W
initial concentration: 0.001
in compartment: meta cell
constant: true
initial amount: NaN
is encoded by: S000006387
is: SBO:0000252
has only substance units: false
boundary condition: true
is: P14020

http://identifiers.org/biomodels.db/BIOMD0000000471#_086421a1_56ac_4c92_8540_0ffdcc6333ac
stoichiometry: 0.0066
species: meta s 1589
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#da21561e_c891_4bb5_8404_4d56802ccdd2
units: dimensionless
value: -1.0
type: LocalParameter

meta e 0106
is encoded by: S000000545
is: SBO:0000252
boundary condition: true
in compartment: meta cell
type: Species
is encoded by: sce:YCL040W
constant: true
name: GLK1
initial amount: NaN
is: P17709
initial concentration: 0.001
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#ec14740a_80be_443d_a319_757768070388
stoichiometry: 1.0
species: meta s 1487
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0536
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initial amount: NaN
has only substance units: false
type: Species
boundary condition: true
is: SBO:0000252
initial concentration: 0.001
is encoded by: S000003834
is: P05375
is encoded by: sce:YJR073C
name: OPI3
constant: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_55048b6e_dc3c_4c3c_8a05_e78938ed8fad
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_1059bd68_7450_4e90_9c42_d83f57502b6a
stoichiometry: 3.0
species: meta s 1212
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0180
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1271
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units: dimensionless
value: -1.0
type: LocalParameter

meta s 0423
is: SBO:0000247
boundary condition: false
initial amount: NaN
constant: false
name: AMP
initial concentration: 0.1
is: CHEBI:456215
is: C00020
type: Species
has only substance units: false
in compartment: meta cell

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 2.0
species: meta s 1399
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0271
type: Species
initial amount: NaN
boundary condition: true
initial concentration: 0.001
has only substance units: false
name: YND1
constant: true
is encoded by: S000000807
is: SBO:0000252
in compartment: meta cell
is: P40009
is encoded by: sce:YER005W

http://identifiers.org/biomodels.db/BIOMD0000000471#_982f32df_d176_4832_a586_c3872aed1e7a
units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 5.30955594768567E-4
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 0.00609896813767666
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0260
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0423
type: SpeciesReference

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value: 2.50486556991948E-4
type: LocalParameter

meta s 1520
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name: trehalose
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initial amount: NaN
is: C01083
is: SBO:0000247
type: Species
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is: CHEBI:16551
constant: false
initial concentration: 0.1

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0434
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stoichiometry: 1.0
species: meta s 0039
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exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 0.00155984810490327
type: LocalParameter

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units: dimensionless
value: 1.0
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units: dimensionless
value: -1.0
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stoichiometry: 1.0
species: meta s 0419
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stoichiometry: 1.0
species: meta s 1427
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stoichiometry: 1.0
species: meta s 0529
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0434
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stoichiometry: 0.2862
species: meta s 1099
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units: dimensionless
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meta s 0750
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initial concentration: 0.1
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units: dimensionless
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value: 0.00251625132250899
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meta e 0531
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initial concentration: 0.001
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name: CYC1
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stoichiometry: 1.0
species: meta s 0455
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units: dimensionless
value: -1.0
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stoichiometry: 1.0
species: meta s 0362
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units: dimensionless
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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
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value: 0.00375691882979276
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units: dimensionless
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stoichiometry: 0.046
species: meta s 0423
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stoichiometry: 1.0
species: meta s 1538
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meta s 1524
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has only substance units: false
name: triglyceride
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boundary condition: false
type: Species
constant: false
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stoichiometry: 1.0
species: meta s 1524
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units: dimensionless
value: -1.0
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stoichiometry: 1.0
species: meta s 1207
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units: dimensionless
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meta s 0573
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is: C00636
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initial amount: NaN
constant: false
boundary condition: false

meta s 0420
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initial amount: NaN
is: CHEBI:28938
is: SBO:0000247
is: C01342
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type: Species
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constant: true
initial concentration: 1.0

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0456
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stoichiometry: 1.0
species: meta s 1212
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value: 0.0105618036280732
type: LocalParameter

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value: 5.86779635397514
type: LocalParameter

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value: 2.04421705708177E-5
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0313
type: SpeciesReference

meta r 0877
fast: false
reversible: true
name: phosphatidylserine decarboxylase
is: R02055
type: Reaction
is: SBO:0000176

meta s 0574
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is: C00275
boundary condition: false
type: Species
initial amount: NaN
constant: false
is: CHEBI:17369
is: SBO:0000247
initial concentration: 0.1
has only substance units: false
in compartment: meta cell

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 0.0024
species: meta s 0589
type: SpeciesReference

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value: 0.106703478027702
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0456
type: SpeciesReference

meta r 0874
fast: false
name: phosphatidylinositol synthase
reversible: true
type: Reaction
is: SBO:0000176
is: R01802

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units: dimensionless
value: -2.0
type: LocalParameter

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value: 0.00107785124523807
type: LocalParameter

meta r 0722
name: mannose-1-phosphate guanylyltransferase
is: R00885
type: Reaction
is: SBO:0000176
reversible: true
fast: false

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value: 0.00251625132251002
type: LocalParameter

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value: 1.02210851263136E-5
type: LocalParameter

meta r 0079
fast: false
is: SBO:0000176
type: Reaction
is: R04463
reversible: true
name: 5'-phosphoribosylformyl glycinamidine synthetase

meta e 0642
is encoded by: S000004079
initial concentration: 0.001
is: P52893
is: SBO:0000252
boundary condition: true
type: Species
constant: true
is encoded by: sce:YLR089C
initial amount: NaN
name: ALT1
has only substance units: false
in compartment: meta cell

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 1.43675988607776
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0300
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

meta s 0577
boundary condition: false
constant: false
type: Species
name: D-ribulose 5-phosphate
initial concentration: 0.1
is: CHEBI:58121
in compartment: meta cell
is: C00199
initial amount: NaN
has only substance units: false
is: SBO:0000247

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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1073
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 0.001583
type: LocalParameter

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value: 2.48095549098117E-4
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 2.56065575909038E-4
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0644
is: SBO:0000252
initial concentration: 0.001
type: Species
constant: true
boundary condition: true
name: ERG27
is: Q12452
initial amount: NaN
is encoded by: sce:YLR100W
in compartment: meta cell
is encoded by: S000004090
has only substance units: false

meta e 0645
is encoded by: S000004099
is encoded by: sce:YLR109W
has only substance units: false
type: Species
constant: true
initial concentration: 0.001
boundary condition: true
is: SBO:0000252
in compartment: meta cell
is: P38013
initial amount: NaN
name: AHP1

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value: 0.00209877372781628
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1048
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0726
is: R00177
reversible: true
fast: false
type: Reaction
is: SBO:0000176
name: methionine adenosyltransferase

http://identifiers.org/biomodels.db/BIOMD0000000471#_32f70e31_6aa1_43d0_881a_edbb67e10cfc
stoichiometry: 1.0
species: meta s 1386
type: SpeciesReference

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value: 1.29987342075721E-4
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0178
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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value: 0.01086200797138
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#ce4de964_a787_4451_a400_2277af9215ca
name: mM
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/BIOMD0000000471#ccd5221c_f311_4507_bb57_7d5248891a3f
units: dimensionless
value: -1.0
type: LocalParameter

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reversible: true
type: Reaction
is: SBO:0000176
name: deoxyadenylate kinase
fast: false

meta r 0723
reversible: true
type: Reaction
is: SBO:0000176
name: mannose-6-phosphate isomerase
fast: false
is: R00772

http://identifiers.org/biomodels.db/BIOMD0000000471#_26e449c4_b375_412b_926a_0f56a01cd950
stoichiometry: 1.0
species: meta s 0454
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1207
type: SpeciesReference

meta s 0141
boundary condition: false
is: C01304
in compartment: meta cell
constant: false
initial amount: NaN
name: 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine
type: Species
initial concentration: 0.1
is: SBO:0000247
is: CHEBI:58614
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_4ab23b41_eeed_40af_bb80_c2b1a8ed7304
value: 3.06632550169132E-5
type: LocalParameter

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stoichiometry: 2.0
species: meta s 1207
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_039a1f4a_b600_4fb1_985d_2b285b34dec1
stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#daf0c1a2_9d4c_4b13_8a35_fe62a7f6cb2a
constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0724
reversible: true
name: methenyltetrahydrifikate cyclohydrolase
fast: false
type: Reaction
is: SBO:0000176
is: R01655

http://identifiers.org/biomodels.db/BIOMD0000000471#bad69c5b_ad25_4dd6_a772_3d49258e0f16
units: dimensionless
value: -1.0
type: LocalParameter

meta s 0142
has only substance units: false
name: 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone
constant: false
initial amount: NaN
type: Species
is: SBO:0000247
in compartment: meta cell
initial concentration: 0.1
boundary condition: false
is: CHEBI:52957

http://identifiers.org/biomodels.db/BIOMD0000000471#_2e9e5733_a31a_4880_8815_5cabb039d75c
stoichiometry: 1.0
species: meta s 0430
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_395d723e_74f6_4a58_8a2e_343f06599744
units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#ba653da9_c3b0_4a21_a6a4_764b43929fb6
stoichiometry: 1.0
species: meta s 1405
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 0.0212913573443156
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_707eb3c7_f461_4324_a36b_6db64ed82a60
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_1f948ee8_0d8a_4e39_844b_9dd10bd25aec
units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 0.0447
species: meta s 0526
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_80cbc11c_76fa_42ac_b917_737c7a861c66
stoichiometry: 1.0
species: meta s 0373
type: SpeciesReference

meta r 0729
reversible: true
fast: false
type: Reaction
is: SBO:0000176
name: methionyl-tRNA synthetase
is: R03659

http://identifiers.org/biomodels.db/BIOMD0000000471#_471e56e7_6be4_4c49_912b_5a85c82a4bf2
stoichiometry: 1.0
species: meta s 0190
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_7605fc15_1e38_4972_95f3_85d1c9ad92b6
units: dimensionless
value: 1.0
type: LocalParameter

meta r 1010
fast: false
reversible: true
name: squalene epoxidase (NAD)
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#_06638b13_1c78_4634_b46c_93b8059fb69d
constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#b39c7b38_2b2a_4c75_9f43_67748658da5a
stoichiometry: 1.0
species: meta s 1039
type: SpeciesReference

meta s 0146
is: C00900
has only substance units: false
initial concentration: 0.1
name: 2-acetyllactic acid
constant: false
type: Species
boundary condition: false
in compartment: meta cell
is: CHEBI:57774
is: SBO:0000247
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000471#fdb18ff4_1bf9_4ba8_9bb8_92345a41c753
units: dimensionless
value: 1.0
type: LocalParameter

meta e 0962
is: SBO:0000252
constant: true
is: P23254
name: TKL1
initial concentration: 0.001
has only substance units: false
in compartment: meta cell
is encoded by: S000006278
is encoded by: sce:YPR074C
boundary condition: true
type: Species
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000471#_5877ae37_6a4a_491f_ba30_b576e15f89ba
stoichiometry: 3.0
species: meta s 1101
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 1011
reversible: true
name: squalene epoxidase (NADP)
is: R02874
fast: false
type: Reaction
is: SBO:0000176

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 0.00387115588078469
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#faf6a2fe_d7cf_4e6c_85d3_ec8a82d17dd9
stoichiometry: 1.0
species: meta s 1271
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

meta r 0727
reversible: true
is: R00946
fast: false
type: Reaction
is: SBO:0000176
name: methionine synthase

meta s 0145
initial concentration: 0.1
is: C01250
in compartment: meta cell
constant: false
type: Species
boundary condition: false
is: SBO:0000247
is: CHEBI:29123
initial amount: NaN
has only substance units: false
name: 2-acetamido-5-oxopentanoate

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1445
type: SpeciesReference

meta e 0860
in compartment: meta cell
has only substance units: false
initial amount: NaN
initial concentration: 0.001
type: Species
is: SBO:0000252
is: P21264
is encoded by: sce:YOR128C
constant: true
boundary condition: true
name: ADE2
is encoded by: S000005654

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0594
is: SBO:0000176
is: R03364
fast: false
reversible: true
name: IPC synthase
type: Reaction

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value: 0.00375691882979276
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 1012
is: SBO:0000176
reversible: true
is: R06223
name: squalene synthase
fast: false
type: Reaction

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value: 3.08174379214594E-5
type: LocalParameter

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value: 0.00251625132250899
type: LocalParameter

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stoichiometry: 0.2646
species: meta s 1614
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1535
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 6.0
species: meta s 1212
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stoichiometry: 1.0
species: meta s 1377
type: SpeciesReference

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stoichiometry: 2.0
species: meta s 0328
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0394
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1021
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stoichiometry: 1.0
species: meta s 1039
type: SpeciesReference

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units: dimensionless
value: 8.92666666666666E-4
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0862
initial amount: NaN
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is encoded by: sce:YOR136W
boundary condition: true
type: Species
is: SBO:0000252
name: IDH2
is: P28241
constant: true
is encoded by: S000005662
initial concentration: 0.001
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_518a79bf_2826_4251_a8d4_719d03016af0
value: 0.0193330078987431
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0644
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meta e 0867
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meta s 0743
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meta s 0207
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boundary condition: false
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is: SBO:0000247
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meta e 0756
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units: dimensionless
value: -1.0
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units: dimensionless
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species: meta s 1616
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constant: true
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is: SBO:0000252
name: TSA2
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meta s 0231
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is: SBO:0000247
is: C02934
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name: 3-ketosphinganine
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units: dimensionless
value: -1.0
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units: dimensionless
value: -2.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0393
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units: dimensionless
value: -1.0
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meta r 0061
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type: Reaction
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is: R04426
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stoichiometry: 1.0
species: meta s 1029
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units: dimensionless
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is: C04411
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has only substance units: false
name: (2R,3S)-3-isopropylmalate

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stoichiometry: 1.0
species: meta s 1003
type: SpeciesReference

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constant: true
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stoichiometry: 1.0
species: meta s 1447
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stoichiometry: 1.0
species: meta s 0367
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is: R04001
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meta s 0008
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boundary condition: false
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is: C06007
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constant: false
is: SBO:0000247
initial concentration: 0.1

meta e 0724
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units: dimensionless
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meta e 0875
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boundary condition: true
is: SBO:0000252
name: HIS3
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type: Species

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value: 0.00187447440148864
type: LocalParameter

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constant: true
value: 0.1
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fast: false
is: SBO:0000176
name: fatty-acid--CoA ligase (dodecanoate)
reversible: true
type: Reaction

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constant: true
value: 0.1
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stoichiometry: 1.0
species: meta s 0837
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meta e 0234
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constant: true
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is encoded by: S000002862
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is encoded by: sce:YDR454C
initial concentration: 0.001

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constant: true
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units: dimensionless
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units: dimensionless
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meta s 0349
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name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid
initial amount: NaN
is: SBO:0000247
boundary condition: false
type: Species

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value: 0.0768531341901953
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stoichiometry: 1.0
species: meta s 0394
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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
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units: dimensionless
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stoichiometry: 1.0
species: meta s 1620
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units: dimensionless
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constant: true
value: 0.1
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stoichiometry: 1.0
species: meta s 1198
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meta e 0237
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initial concentration: 0.001
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meta e 0729
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constant: true
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name: ARG7
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units: dimensionless
value: 1.0
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units: dimensionless
value: 1.0
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meta s 0739
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is: CHEBI:58189
constant: false
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boundary condition: false
is: SBO:0000247

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units: dimensionless
value: -1.0
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constant: true
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units: dimensionless
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meta e 0872
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boundary condition: true
is: P33330
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is: SBO:0000252
name: SER1

meta r 0739
is: R01121
is: SBO:0000176
name: mevalonate pyrophoshate decarboxylase
type: Reaction
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reversible: true

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value: 0.00187447440148675
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value: 1.36629031085814E-4
type: LocalParameter

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units: dimensionless
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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0835
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stoichiometry: 1.0
species: meta s 1620
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stoichiometry: 1.0
species: meta s 0313
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stoichiometry: 1.0
species: meta s 1212
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stoichiometry: 8.12E-4
species: meta s 0672
type: SpeciesReference

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units: dimensionless
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value: 0.00107785124523996
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value: 0.0047288825765441
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units: dimensionless
value: -1.0
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units: dimensionless
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meta s 0232
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units: dimensionless
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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0394
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meta e 0239
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name: SAM2
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type: Species
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is encoded by: sce:YDR502C
constant: true
is: P19358

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stoichiometry: 1.0
species: meta s 0434
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meta e 0955
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constant: true
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units: dimensionless
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meta e 0129
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type: Species
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initial concentration: 0.001

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units: dimensionless
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units: dimensionless
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value: 2.56634863390825E-4
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stoichiometry: 1.0
species: meta s 1559
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value: 2.56634863390825E-4
type: LocalParameter

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value: 1.02210849818021E-5
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meta e 0128
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value: 0.087517608841966
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stoichiometry: 1.0
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units: dimensionless
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value: 0.0306618317263325
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meta e 0953
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type: Species
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units: dimensionless
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stoichiometry: 1.0
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species: meta s 0118
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value: 5.10195573579038E-4
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stoichiometry: 1.0
species: meta s 1343
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units: dimensionless
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type: Species
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is: SBO:0000252
initial amount: NaN
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type: Reaction
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reversible: true
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units: dimensionless
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units: dimensionless
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meta e 0510
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constant: true
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meta s 0445
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constant: true
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species: meta s 1032
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meta r 0858
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type: Reaction
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meta e 0512
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meta s 1099
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meta e 0514
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stoichiometry: 1.0
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units: dimensionless
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meta e 0515
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meta s 0555
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meta s 0557
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0493
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meta e 0888
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meta r 0300
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type: Reaction
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is: SBO:0000176

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meta s 0018
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meta r 0302
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meta e 0737
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stoichiometry: 1.0
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stoichiometry: 1.0
species: meta s 0304
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type: Species

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stoichiometry: 1.0
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meta e 0889
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stoichiometry: 1.0
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meta s 0120
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units: dimensionless
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meta e 0883
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meta s 0725
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is: CHEBI:29806
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stoichiometry: 1.0
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value: 0.0112491235594554
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value: 8.88088702058448E-4
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value: 0.00419754745504612
type: LocalParameter

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value: 1.36629031089924E-4
type: LocalParameter

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units: dimensionless
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meta e 0940
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boundary condition: true
is: P08417
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stoichiometry: 1.0
species: meta s 0386
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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 0.1647
type: LocalParameter

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units: dimensionless
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type: LocalParameter

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constant: false
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is: C00058
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type: Species
is: SBO:0000247
initial concentration: 0.1
initial amount: NaN
in compartment: meta cell
is: CHEBI:15740

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0542
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units: dimensionless
value: -1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

meta s 0010
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initial concentration: 0.1
initial amount: NaN
in compartment: meta cell
is: C04236
type: Species
boundary condition: false
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constant: false
has only substance units: false

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units: dimensionless
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type: LocalParameter

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units: dimensionless
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type: LocalParameter

meta s 0723
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in compartment: meta extracellular
is: CHEBI:15740
type: Species
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constant: true
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initial amount: NaN
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boundary condition: true

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units: dimensionless
value: -1.0
type: LocalParameter

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type: LocalParameter

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type: LocalParameter

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units: dimensionless
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type: LocalParameter

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units: dimensionless
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type: LocalParameter

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units: dimensionless
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type: LocalParameter

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units: dimensionless
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type: LocalParameter

meta r 0309
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type: Reaction
is: R01290
fast: false
reversible: true
is: SBO:0000176

http://identifiers.org/biomodels.db/BIOMD0000000471#_1fc54c4f_0a52_4bdf_bead_d5c62e101be1
stoichiometry: 1.0
species: meta s 0644
type: SpeciesReference

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value: 0.0100308480322675
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

meta e 0139
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type: Species
in compartment: meta cell
initial concentration: 0.001
is encoded by: S000002243
is: Q07500
boundary condition: true
is: SBO:0000252
has only substance units: false
initial amount: NaN
constant: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_994417dc_b4b0_40be_ab64_940d776052d0
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_257275f1_26dc_4ebf_ab99_eb60251698cc
stoichiometry: 1.0
species: meta s 0739
type: SpeciesReference

meta e 0243
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name: QCR7
is encoded by: S000002937
initial concentration: 0.001
has only substance units: false
in compartment: meta cell
type: Species
boundary condition: true
is encoded by: sce:YDR529C
is: P00128

meta s 0015
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is: CHEBI:57472
initial amount: NaN
has only substance units: false
type: Species
is: C03406
constant: false
initial concentration: 0.1
boundary condition: false
name: (N(omega)-L-arginino)succinic acid

http://identifiers.org/biomodels.db/BIOMD0000000471#_173e2342_319d_4392_bbb6_22f8d9c2499e
stoichiometry: 1.0
species: meta s 1351
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#e6deb2e6_d465_450b_87df_ae10845207b7
stoichiometry: 1.0
species: meta s 0393
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_2e8ef353_e977_4b3a_8dd7_4b42395d522d
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_26fdd6a0_09ca_4c63_9c1f_9f0d8056c680
stoichiometry: 1.0
species: meta s 0785
type: SpeciesReference

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value: 0.00155984810490327
type: LocalParameter

meta e 0242
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initial amount: NaN
is encoded by: S000002921
name: GRX2
initial concentration: 0.001
is: SBO:0000252
in compartment: meta cell
has only substance units: false
is: P17695
constant: true
boundary condition: true
type: Species

meta e 0137
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is: SBO:0000252
is: P32419
initial concentration: 0.001
is encoded by: sce:YDL078C
type: Species
constant: true
boundary condition: true
in compartment: meta cell
has only substance units: false
initial amount: NaN

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units: dimensionless
value: -1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

meta e 0947
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is encoded by: S000006205
is: P43635
type: Species
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name: CIT3
in compartment: meta cell
is: SBO:0000252

meta e 0733
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in compartment: meta cell
initial amount: NaN
type: Species
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is encoded by: sce:YMR105C
is: SBO:0000252
is: P37012
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name: PGM2

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value: 0.01004223378483
type: LocalParameter

meta e 0136
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type: Species
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is encoded by: sce:YDL067C
is: P07255
initial amount: NaN
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is encoded by: S000002225

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units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#af7cc117_cbd5_4bb5_8077_122bb2c23140
units: dimensionless
value: 1.0
type: LocalParameter

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is: SBO:0000176
name: fatty-acyl-CoA synthase (n-C18:0CoA)
type: Reaction
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http://identifiers.org/biomodels.db/BIOMD0000000471#_61778e4a_28be_4607_a83c_4d50d49f1614
units: dimensionless
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type: LocalParameter

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constant: true
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type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_3cbeb80d_aa80_490a_8329_f957adca7ac2
constant: true
value: 0.1
type: Parameter

meta s 0016
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in compartment: meta cell
is: CHEBI:49072
initial concentration: 0.1
is: SBO:0000247
initial amount: NaN
is: C04272
boundary condition: false

meta e 0135
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is: P21954
is encoded by: S000002224
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boundary condition: true
is: SBO:0000252
constant: true
type: Species
has only substance units: false
in compartment: meta cell

http://identifiers.org/biomodels.db/BIOMD0000000471#c48f1b88_2d73_4e95_a9c4_31285f17ae11
stoichiometry: 1.0
species: meta s 0322
type: SpeciesReference

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units: dimensionless
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http://identifiers.org/biomodels.db/BIOMD0000000471#_69caf507_bac6_4b16_afa4_84f65db491a2
units: dimensionless
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type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#bbbeb152_f2e9_4109_80c3_80044206b3bd
value: 2.50486556991948E-4
type: LocalParameter

meta r 0536
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type: Reaction
fast: false
reversible: true
is: R01158

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value: 0.00107785124523807
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_8dea7d7d_ee67_44ec_82de_a284286d2c16
value: 0.01086200797138
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#db887be1_e26e_4f42_9647_82c9fb0aca28
stoichiometry: 1.0
species: meta s 1207
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#d307944c_3e5b_4a39_9a85_635645ef5558
value: 0.892327912279146
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#d0e80829_8239_46fc_8810_461e9c66e414
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#e1e370b9_5d93_4823_bad5_52654d55b1e3
stoichiometry: 1.0
species: meta s 1006
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http://identifiers.org/biomodels.db/BIOMD0000000471#_61d02120_96fe_4210_be88_a4cb65688772
stoichiometry: 1.0
species: meta s 1577
type: SpeciesReference

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stoichiometry: 3.0
species: meta s 0456
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 1063
reversible: true
type: Reaction
is: SBO:0000176
fast: false
name: tyrosine transaminase
is: R00734

W3 CDTF: Wed Feb 20 10:05:10 GMT 2008

http://identifiers.org/biomodels.db/BIOMD0000000471#_14ef806f_348c_410c_8163_349e05741a95
units: dimensionless
value: 1.0
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stoichiometry: 1.0
species: meta s 0291
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stoichiometry: 1.0
species: meta s 0456
type: SpeciesReference

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value: 0.0430685067991607
type: LocalParameter

meta s 0475
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is: CHEBI:52961
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has only substance units: false

meta r 0534
reversible: true
name: hexokinase (D-glucose:ATP)
fast: false
is: SBO:0000176
type: Reaction
is: R00299

http://identifiers.org/biomodels.db/BIOMD0000000471#d0d60776_aa1d_44a0_8565_ee745e1f73a2
stoichiometry: 1.0
species: meta s 1447
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units: dimensionless
value: -2.0
type: LocalParameter

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constant: true
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type: Parameter

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units: dimensionless
value: 1.0
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W3 CDTF: Mon Oct 07 22:27:32 BST 2013

meta r 0757
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type: Reaction
is: SBO:0000176
reversible: true
name: myo-inositol 1-phosphatase
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http://identifiers.org/biomodels.db/BIOMD0000000471#_7b5c35ac_809f_4ac2_89b8_25f1f5e204f7
units: dimensionless
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stoichiometry: 1.0
species: meta s 1032
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constant: true
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type: Parameter

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stoichiometry: 1.0
species: meta s 1416
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stoichiometry: 1.0
species: meta s 0849
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constant: true
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type: Parameter

meta s 1405
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initial amount: NaN
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is: C00255
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has only substance units: false
constant: false
name: riboflavin

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value: 0.00508184090605392
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0145
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units: dimensionless
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value: 0.01004223378483
type: LocalParameter

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value: 0.00107785124523996
type: LocalParameter

meta s 0178
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initial concentration: 0.1
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constant: false
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has only substance units: false
in compartment: meta cell

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units: dimensionless
value: 1.25E-4
type: LocalParameter

meta s 1270
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has only substance units: false
is: C01103
name: orotidine 5'-(dihydrogen phosphate)
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in compartment: meta cell
initial concentration: 0.1
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value: 0.00726411015276989
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0991
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http://identifiers.org/biomodels.db/BIOMD0000000471#_0a27b9bd_497d_4771_91e7_b6e80fc43ae0
units: dimensionless
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type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_5c881d67_48c1_4c02_a725_5553a4a9127f
stoichiometry: 0.5185
species: meta s 0773
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http://identifiers.org/biomodels.db/BIOMD0000000471#_52f3ba22_f537_4b18_b833_f1cdcc8ac03c
units: dimensionless
value: 1.0
type: LocalParameter

meta r 1066
type: Reaction
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fast: false
reversible: true
is: R02918
name: tyrosyl-tRNA synthetase

http://identifiers.org/biomodels.db/BIOMD0000000471#_785a1091_4594_4f38_ae45_1cfdea1f335f
stoichiometry: 1.0
species: meta s 1014
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stoichiometry: 1.0
species: meta s 0567
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meta s 1271
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type: Species
is: C00036
is: SBO:0000247
constant: false
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has only substance units: false
initial amount: NaN
in compartment: meta cell

meta r 0759
fast: false
type: Reaction
is: SBO:0000176
name: N-acetyl-g-glutamyl-phosphate reductase
reversible: true
is: R03443

http://identifiers.org/biomodels.db/BIOMD0000000471#_721dc363_6bcf_400d_9cdf_f8782fbd5f4f
stoichiometry: 1.0
species: meta s 1101
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stoichiometry: 1.0
species: meta s 0633
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stoichiometry: 1.0
species: meta s 0969
type: SpeciesReference

meta r 0470
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is: SBO:0000176
name: glutamate dehydrogenase (NAD)
type: Reaction
fast: false

meta e 0364
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in compartment: meta cell
initial concentration: 0.001
initial amount: NaN
has only substance units: false
is: SBO:0000252
is encoded by: S000003264
boundary condition: true
type: Species
name: GSC2

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value: 2.50486556092046E-4
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_0bb291d1_2c1a_4fba_ae98_8e96229e4863
value: 0.0193330078983478
type: LocalParameter

meta s 0176
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is: SBO:0000247
has only substance units: false
is: C00322
constant: false
initial amount: NaN
is: CHEBI:57499
initial concentration: 0.1
in compartment: meta cell
type: Species
name: 2-oxoadipic acid

meta s 0471
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is: C00269
is: SBO:0000247
constant: false
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initial amount: NaN
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units: dimensionless
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stoichiometry: 1.0
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value: 0.00627317015230181
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 3.0
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units: dimensionless
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has only substance units: false
type: Species
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is: P47190

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0943
type: SpeciesReference

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units: dimensionless
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stoichiometry: 1.0
species: meta s 1322
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stoichiometry: 1.0
species: meta s 1198
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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0434
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constant: true
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type: Parameter

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is: SBO:0000252
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is encoded by: sce:YGR037C
is encoded by: S000003269
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is: P31787
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meta s 1275
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initial concentration: 0.1
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is: CHEBI:15379
type: Species
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stoichiometry: 1.0
species: meta s 1275
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stoichiometry: 1.0
species: meta s 0162
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stoichiometry: 1.0
species: meta s 1322
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units: dimensionless
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type: LocalParameter

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type: LocalParameter

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is encoded by: S000003293
constant: true
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type: Species
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initial amount: NaN
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boundary condition: true
is: SBO:0000252

http://identifiers.org/biomodels.db/BIOMD0000000471#_5eca8642_ef43_45ee_ad34_956ae0c51aca
stoichiometry: 0.1017
species: meta s 0430
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0028
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units: dimensionless
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initial amount: NaN
constant: true
name: ERG25
is encoded by: sce:YGR060W
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initial concentration: 0.001
is: P53045

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stoichiometry: 2.0
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units: dimensionless
value: 5.6E-5
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stoichiometry: 1.0
species: meta s 0782
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meta s 1559
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initial amount: NaN
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is: C00075
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boundary condition: false
constant: false
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value: 0.00251625132250899
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units: dimensionless
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meta r 0479
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is: R05578
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fast: false

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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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meta e 0926
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stoichiometry: 1.0
species: meta s 1207
type: SpeciesReference

ORG:
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n:
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meta r 0539
is: SBO:0000176
is: R03655
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units: dimensionless
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meta r 0478
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reversible: true
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value: 9.19873934027924E-6
type: LocalParameter

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units: dimensionless
value: 8.12E-4
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units: dimensionless
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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0633
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units: dimensionless
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units: dimensionless
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units: dimensionless
value: 1.0
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meta r 0538
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type: Reaction
reversible: true

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stoichiometry: 1.0
species: meta s 1271
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meta r 0476
is: SBO:0000176
type: Reaction
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reversible: true

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constant: true
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stoichiometry: 1.0
species: meta s 0409
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meta s 1277
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meta r 0537
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type: Reaction
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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initial concentration: 0.1
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meta e 0934
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boundary condition: true
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is: SBO:0000252
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constant: true

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units: dimensionless
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units: dimensionless
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fast: false
type: Reaction
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reversible: true
is: SBO:0000176

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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0973
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type: LocalParameter

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value: 2.04421702621944E-5
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type: LocalParameter

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value: 1.02210838883012E-5
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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value: 6.43295039602845E-5
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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 1.0
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constant: true
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meta e 0296
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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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meta e 0788
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meta e 0297
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meta r 0970
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is: SBO:0000176
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meta s 1101
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in compartment: meta cell
constant: false
initial concentration: 0.1
initial amount: NaN
type: Species
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value: 0.00965062714998262
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type: Parameter

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units: dimensionless
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meta e 0298
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stoichiometry: 0.2975
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meta r 0313
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meta r 0311
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meta s 0188
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is: CHEBI:58289
boundary condition: false
in compartment: meta cell
has only substance units: false
constant: false
name: 2-phospho-D-glyceric acid
type: Species
is: SBO:0000247
initial concentration: 0.1
is: C00631

meta e 0376
is encoded by: sce:YGR124W
boundary condition: true
in compartment: meta cell
constant: true
is: P49090
is encoded by: S000003356
initial concentration: 0.001
initial amount: NaN
name: ASN2
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is: SBO:0000252
type: Species

meta s 1565
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is: C00655
type: Species
is: CHEBI:57464
initial amount: NaN
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has only substance units: false
is: SBO:0000247
name: xanthosine-5-phosphate
boundary condition: false
constant: false

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0516
type: SpeciesReference

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units: dimensionless
value: 0.0234
type: LocalParameter

meta r 0542
type: Reaction
name: homoacontinate hydratase
is: R04371
reversible: true
fast: false
is: SBO:0000176

meta r 0481
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fast: false
is: R00115
reversible: true
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#_60998800_499b_489d_88f7_f864973e9c83
stoichiometry: 1.0
species: meta s 0037
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 1052
type: Reaction
is: SBO:0000176
fast: false
name: triacylglycerol lipase
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000471#dc1b2ed7_72c2_4bf5_8267_475d4b08aef7
units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 58.70001
species: meta s 1322
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0146
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1322
type: SpeciesReference

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units: dimensionless
value: 1.0
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meta s 1413
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initial concentration: 0.1
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is: SBO:0000247
name: S-adenosyl-L-homocysteine
constant: false
boundary condition: false
type: Species

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stoichiometry: 1.0
species: meta s 1038
type: SpeciesReference

meta e 0160
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name: GDH2
boundary condition: true
is encoded by: S000002374
constant: true
initial concentration: 0.001
is encoded by: sce:YDL215C
in compartment: meta cell
is: P33327
type: Species
is: SBO:0000252
initial amount: NaN

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stoichiometry: 1.0
species: meta s 0557
type: SpeciesReference

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units: dimensionless
value: 0.2862
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0394
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units: dimensionless
value: -1.0
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meta r 0483
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name: glutathione peridoxase
is: SBO:0000176
reversible: true
type: Reaction
is: R00274

meta r 0330
fast: false
is: R02090
name: deoxyguanylate kinase (dGMP:ATP)
is: SBO:0000176
reversible: true
type: Reaction

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value: 1.46007394609031
type: LocalParameter

meta r 1054
type: Reaction
is: SBO:0000176
name: triose-phosphate isomerase
fast: false
reversible: true

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0574
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1569
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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0543
fast: false
type: Reaction
name: homocitrate synthase
is: R00271
reversible: true
is: SBO:0000176

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units: dimensionless
value: -1.0
type: LocalParameter

meta r 1055
fast: false
reversible: true
type: Reaction
is: SBO:0000176
name: tryptophan synthase (indoleglycerol phosphate)

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value: 0.0212913573443156
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1212
type: SpeciesReference

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value: 1.29987342075721E-4
type: LocalParameter

meta s 1569
is: CHEBI:18252
boundary condition: false
is: C05437
in compartment: meta cell
constant: false
has only substance units: false
initial concentration: 0.1
is: SBO:0000247
name: zymosterol
initial amount: NaN
type: Species

meta r 0699
type: Reaction
fast: false
is: R01090
reversible: true
is: SBO:0000176
name: leucine transaminase

http://identifiers.org/biomodels.db/BIOMD0000000471#fe35e67a_cbff_473f_b739_de5cb71db14e
units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0314
type: SpeciesReference

meta r 0698
is: R03199
is: SBO:0000176
fast: false
name: lanosterol synthase
reversible: true
type: Reaction

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stoichiometry: 1.0
species: meta s 0629
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0793
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is encoded by: sce:YNL247W
has only substance units: false
constant: true
boundary condition: true
is: P53852
is encoded by: S000005191
initial concentration: 0.001
is: SBO:0000252
name: YNL247W
in compartment: meta cell
type: Species

meta e 0379
initial amount: NaN
constant: true
boundary condition: true
is: SBO:0000252
initial concentration: 0.001
is encoded by: S000003375
is encoded by: sce:YGR143W
type: Species
name: SKN1
is: P33336
in compartment: meta cell
has only substance units: false

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stoichiometry: 1.0
species: meta s 1039
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 0.1914
species: meta s 1491
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0991
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units: dimensionless
value: -1.0
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units: dimensionless
value: -1.0
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http://identifiers.org/biomodels.db/BIOMD0000000471#_6eceef5f_e24a_4847_98ad_d6ab9222ecae
units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0568
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http://identifiers.org/biomodels.db/BIOMD0000000471#_08b3e597_60b9_4520_af49_f665cf2f1696
stoichiometry: 1.0
species: meta s 1212
type: SpeciesReference

meta r 0486
fast: false
name: glyceraldehyde-3-phosphate dehydrogenase
reversible: true
is: SBO:0000176
type: Reaction

meta e 0603
boundary condition: true
is: P36143
is encoded by: S000001766
name: GLG1
initial amount: NaN
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is: SBO:0000252
constant: true
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is encoded by: sce:YKR058W
type: Species
initial concentration: 0.001

http://identifiers.org/biomodels.db/BIOMD0000000471#_148705dc_b27c_4e9d_835d_5f18ddc1bd12
stoichiometry: 1.0
species: meta s 0456
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units: dimensionless
value: -1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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value: 0.00627317015230181
type: LocalParameter

meta s 0467
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has only substance units: false
is: SBO:0000247
initial amount: NaN
boundary condition: false
is: CHEBI:58069
initial concentration: 0.1
type: Species
constant: false
is: C00112

meta s 0180
type: Species
boundary condition: false
initial amount: NaN
is: CHEBI:16810
is: C00026
name: 2-oxoglutarate
constant: false
is: SBO:0000247
initial concentration: 0.1
in compartment: meta cell
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#ffa5a784_553a_421b_8694_36855736dd90
stoichiometry: 1.0
species: meta s 0232
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_50f5aebc_72a2_4a09_b17c_a46ee0f21bbb
stoichiometry: 1.0
species: meta s 1233
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#d981252a_de3c_45cf_aa33_038eaf6ce42e
stoichiometry: 1.0
species: meta s 1366
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_66cee6b1_b52e_4fd1_88e2_636203befb11
units: dimensionless
value: -3.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0785
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stoichiometry: 0.0507
species: meta s 1602
type: SpeciesReference

meta r 0549
is: R01776
type: Reaction
reversible: true
fast: false
is: SBO:0000176
name: homoserine O-trans-acetylase

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value: 0.00375691882979276
type: LocalParameter

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is: SBO:0000185
fast: false
reversible: false
name: formate transport
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#a8825c30_4e17_42fc_8b7d_06d3662a33aa
units: dimensionless
value: 1.0
type: LocalParameter

meta e 0915
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boundary condition: true
constant: true
initial concentration: 0.001
is: SBO:0000252
in compartment: meta cell
is: P41921
type: Species
initial amount: NaN
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is encoded by: sce:YPL091W
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_6f1b4024_c4c5_4f98_be37_262dbf6f82b3
stoichiometry: 1.0
species: meta s 1449
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units: dimensionless
value: -1.0
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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0259
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meta s 1266
initial amount: NaN
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is: SBO:0000247
is: CHEBI:46912
name: ornithine
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is: C01602
type: Species
boundary condition: false
constant: false
initial concentration: 0.1

http://identifiers.org/biomodels.db/BIOMD0000000471#_22945886_09bb_4c67_a7e4_da17854a3078
stoichiometry: 1.0
species: meta s 1014
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meta e 0607
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boundary condition: true
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initial concentration: 0.001
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name: GPT2
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is: SBO:0000252
constant: true

http://identifiers.org/biomodels.db/BIOMD0000000471#a250fd7f_61b8_4eff_b376_dae6c4960d45
stoichiometry: 1.0
species: meta s 0973
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units: dimensionless
value: 1.0
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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0914
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is: SBO:0000252
is encoded by: S000006008
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constant: true
is: Q02896
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http://identifiers.org/biomodels.db/BIOMD0000000471#_364a2e6d_00d0_4d29_9662_76239918148e
stoichiometry: 1.0
species: meta s 1416
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units: dimensionless
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units: dimensionless
value: 1.0
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stoichiometry: 1.0
species: meta s 0301
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units: dimensionless
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meta e 0791
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stoichiometry: 1.0
species: meta s 1487
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units: dimensionless
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meta s 1269
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is: SBO:0000247
has only substance units: false
in compartment: meta cell
name: orotate
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is: CHEBI:30839
constant: false

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value: 2.93389817698765
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units: dimensionless
value: -1.0
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stoichiometry: 1.0
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constant: true
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stoichiometry: 3.9E-4
species: meta s 1337
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constant: true
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type: Parameter

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stoichiometry: 0.1054
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value: 0.00965062714996943
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units: dimensionless
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stoichiometry: 1.0
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stoichiometry: 1.0
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units: dimensionless
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meta s 0039
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boundary condition: false
type: Species
constant: false
initial concentration: 0.1
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units: dimensionless
value: 0.0663
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value: 6.43295039602845E-5
type: LocalParameter

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units: dimensionless
value: 0.0036
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constant: true
value: 0.1
type: Parameter

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units: dimensionless
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type: Species
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name: IDI1
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stoichiometry: 4.0
species: meta s 0709
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stoichiometry: 1.0
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stoichiometry: 3.0
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n:
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stoichiometry: 1.0
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ORG:
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n:
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value: 0.0100308480322675
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stoichiometry: 1.0
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constant: true
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constant: true
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meta r 0770
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value: 1.50557601754342E-4
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units: dimensionless
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value: 3.06632551696157E-5
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value: 2.58760203874159E-4
type: LocalParameter

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stoichiometry: 0.0663
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species: meta s 0037
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meta r 1057
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value: 0.1
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value: 0.00375691882979276
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stoichiometry: 1.0
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type: LocalParameter

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stoichiometry: 0.0056
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units: dimensionless
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units: dimensionless
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meta r 0988
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value: 0.850333043996831
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stoichiometry: 1.0
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stoichiometry: 1.0
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meta r 0986
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meta s 0313
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stoichiometry: 1.0
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meta e 0380
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meta r 1042
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type: Reaction
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stoichiometry: 1.0
species: meta s 1255
type: SpeciesReference

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constant: true
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type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 0.00703639510095562
type: LocalParameter

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boundary condition: true
initial concentration: 0.001
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is encoded by: sce:YKR089C

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is: P05150
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initial amount: NaN
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initial concentration: 0.001

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constant: true
value: 0.1
type: Parameter

meta r 0880
is: R01800
type: Reaction
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is: SBO:0000176
reversible: true

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stoichiometry: 1.0
species: meta s 1399
type: SpeciesReference

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units: dimensionless
value: 3.0
type: LocalParameter

meta r 0212
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is: R03648
is: SBO:0000176
reversible: true

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1360
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1275
type: SpeciesReference

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units: dimensionless
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boundary condition: true

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constant: true
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units: dimensionless
value: -1.0
type: LocalParameter

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boundary condition: true
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is encoded by: S000002444
initial concentration: 0.001
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is: SBO:0000252

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units: dimensionless
value: -1.0
type: LocalParameter

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reversible: true
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type: Reaction

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1322
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0211
reversible: true
fast: false
type: Reaction
name: asparagine synthase (glutamine-hydrolysing)
is: R00578
is: SBO:0000176

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stoichiometry: 1.0
species: meta s 1233
type: SpeciesReference

meta r 0340
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is: SBO:0000176
name: dihydroceramidase
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fast: false

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
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meta r 1041
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is: R01466
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fast: false
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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 0.0284
species: meta s 1527
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0467
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stoichiometry: 1.0
species: meta s 0657
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

meta e 0387
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boundary condition: true
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type: Species
is: P49723
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constant: true
is: SBO:0000252

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value: 0.0100308480322675
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0261
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value: 9.44495616410234E-5
type: LocalParameter

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value: 0.00251625132250899
type: LocalParameter

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value: 0.00179092669763194
type: LocalParameter

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units: dimensionless
value: 1.0
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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1203
type: SpeciesReference

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boundary condition: true
type: Species
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initial amount: NaN
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is: SBO:0000252
is encoded by: sce:YGR170W

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units: dimensionless
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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
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stoichiometry: 1.0
species: meta s 1203
type: SpeciesReference

meta s 1427
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type: Species
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is: CHEBI:57483
is: SBO:0000247
initial amount: NaN

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units: dimensionless
value: 1.0
type: LocalParameter

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is: SBO:0000176
reversible: true
type: Reaction

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stoichiometry: 1.0
species: meta s 0262
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0471
type: SpeciesReference

meta e 0381
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type: Species
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name: CHO2
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constant: true
is encoded by: S000003389
is encoded by: sce:YGR157W
is: SBO:0000252
is: P05374
initial concentration: 0.001

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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0559
is: R01978
type: Reaction
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is: SBO:0000176
fast: false
reversible: true

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 0.01086200797138
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1275
type: SpeciesReference

meta s 1428
initial amount: NaN
boundary condition: false
name: Ser-tRNA(Ser)
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initial concentration: 0.1
is: CHEBI:29162
constant: false
in compartment: meta cell

meta r 0344
is: SBO:0000176
fast: false
name: dihydrofolate reductase
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is: R00939
type: Reaction

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units: dimensionless
value: 0.0056
type: LocalParameter

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value: 1.43675988607776
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

meta s 0499
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name: ceramide-4 (C24)
is: CHEBI:60256
has only substance units: false
in compartment: meta cell
type: Species
constant: false
boundary condition: false
initial amount: NaN

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 3.75729835487922E-5
type: LocalParameter

meta r 0558
name: hydroxymethylglutaryl CoA reductase
reversible: true
fast: false
type: Reaction
is: R02082
is: SBO:0000176

meta s 1429
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type: Species
is: SBO:0000247
has only substance units: false
boundary condition: false
initial concentration: 0.1
constant: false
in compartment: meta cell
initial amount: NaN
is: C00493
name: shikimate

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value: 4.08843399368032E-5
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1322
type: SpeciesReference

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value: 0.00251625132250899
type: LocalParameter

meta r 0886
is: R00756
reversible: true
is: SBO:0000176
type: Reaction
fast: false
name: phosphofructokinase

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stoichiometry: 1.0
species: meta s 0019
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value: 0.0014653985431621
type: LocalParameter

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value: 0.0300082373429098
type: LocalParameter

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exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

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units: dimensionless
value: -1.0
type: LocalParameter

meta r 0669
reversible: true
is: SBO:0000176
fast: false
type: Reaction
name: ketol-acid reductoisomerase (2-aceto-2-hydroxybutanoate)

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value: 0.305666406674421
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 0.0212913573443156
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value: 0.00439869575080998
type: LocalParameter

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units: dimensionless
value: 1.0
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meta e 0903
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is: P46151
boundary condition: true
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type: Species
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units: dimensionless
value: 1.0
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units: dimensionless
value: 2.0
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constant: true
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meta e 0490
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constant: true
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meta r 0888
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name: mM per s
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constant: true
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units: dimensionless
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meta r 0667
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value: 2.40277332169094E-4
type: LocalParameter

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initial amount: NaN
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stoichiometry: 1.0
species: meta s 1207
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units: dimensionless
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value: 2.5173898992709E-4
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value: 0.00439869575080998
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value: 1.0
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constant: false
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stoichiometry: 1.0
species: meta s 1413
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constant: true
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initial concentration: 0.001
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is: SBO:0000252

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stoichiometry: 1.0
species: meta s 1003
type: SpeciesReference

meta s 1538
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has only substance units: false
in compartment: meta cell
is: CHEBI:58223
initial concentration: 0.1
name: UDP
initial amount: NaN
is: C00015
boundary condition: false
constant: false

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0180
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0529
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1212
type: SpeciesReference

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type: Species
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is: P10869
is encoded by: sce:YER052C
is encoded by: S000000854
boundary condition: true
initial concentration: 0.001
constant: true
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initial amount: NaN
is: SBO:0000252

http://identifiers.org/biomodels.db/BIOMD0000000471#bd2cad0e_7e36_41d6_904f_8f071be83821
stoichiometry: 2.0
species: meta s 0190
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

meta r 0665
name: isoleucyl-tRNA synthetase
fast: false
reversible: true
is: SBO:0000176
is: R03656
type: Reaction

meta e 0495
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is: SBO:0000252
type: Species
initial concentration: 0.001
name: TDH1
constant: true
initial amount: NaN
has only substance units: false
is: P00360
is encoded by: sce:YJL052W
boundary condition: true
in compartment: meta cell

meta r 0451
is: SBO:0000176
name: fumarase
is: R01082
type: Reaction
reversible: true
fast: false

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value: 2.04421699920047E-5
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0280
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is encoded by: sce:YER043C
constant: true
boundary condition: true
is: SBO:0000252
initial concentration: 0.001
type: Species
initial amount: NaN
is encoded by: S000000845

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stoichiometry: 1.0
species: meta s 1520
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0389
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initial concentration: 0.001
initial amount: NaN
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is encoded by: S000003415
name: QCR9
is encoded by: sce:YGR183C
boundary condition: true
constant: true
has only substance units: false

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stoichiometry: 1.0
species: meta s 1537
type: SpeciesReference

meta r 0450
name: fructose-bisphosphate aldolase
type: Reaction
fast: false
reversible: true
is: SBO:0000176

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stoichiometry: 1.0
species: meta s 0445
type: SpeciesReference

meta e 0615
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boundary condition: true
type: Species
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is: SBO:0000252
constant: true
initial amount: NaN
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name: DPS1
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is encoded by: S000003941
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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0456
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

meta e 0283
type: Species
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constant: true
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initial concentration: 0.001
boundary condition: true
initial amount: NaN
in compartment: meta cell
name: HIS1
is: P00498
is encoded by: S000000857
is: SBO:0000252

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stoichiometry: 2.0
species: meta s 1212
type: SpeciesReference

meta s 1533
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is: SBO:0000247
constant: false
type: Species
has only substance units: false
initial amount: NaN
boundary condition: false
is: C02839
initial concentration: 0.1
in compartment: meta cell
name: Tyr-tRNA(Tyr)

http://identifiers.org/biomodels.db/BIOMD0000000471#f4ac4857_12f5_47ef_80b6_ed5803841a41
stoichiometry: 1.0
species: meta s 1616
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0390
type: SpeciesReference

meta r 0663
reversible: true
type: Reaction
is: SBO:0000176
is: R02199
name: isoleucine transaminase
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000471#f58a0224_9a8b_4390_b501_d5dedcb55c30
stoichiometry: 1.0
species: meta s 1035
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 0.00385977012819758
type: LocalParameter

meta s 0782
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is: C00144
type: Species
has only substance units: false
is: SBO:0000247
initial concentration: 0.1
initial amount: NaN
boundary condition: false
is: CHEBI:58115
name: GMP
constant: false

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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0496
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name: BNA3
constant: true
has only substance units: false
is: SBO:0000252
in compartment: meta cell
boundary condition: true
type: Species
initial concentration: 0.001
is encoded by: sce:YJL060W
initial amount: NaN
is: P47039

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type: Reaction
is: SBO:0000176
fast: false
name: mevalonate kinase (ctp)
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_0898bf2a_535c_449f_b5d6_9542b46edd29
stoichiometry: 1.0
species: meta s 0943
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#b75044e8_0b5c_4e60_b337_cd98bc674f02
units: dimensionless
value: 1.0
type: LocalParameter

meta e 0613
is: Q07804
name: YEH1
type: Species
constant: true
is: SBO:0000252
is encoded by: sce:YLL012W
has only substance units: false
initial concentration: 0.001
is encoded by: S000003935
initial amount: NaN
boundary condition: true
in compartment: meta cell

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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0904
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initial concentration: 0.001
initial amount: NaN
is: SBO:0000252
is encoded by: sce:YPL028W
constant: true
has only substance units: false
name: ERG10
is encoded by: S000005949
is: P41338
in compartment: meta cell
type: Species

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value: 3.06632551696157E-5
type: LocalParameter

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value: 0.0306618317263325
type: LocalParameter

meta r 0993
fast: false
type: Reaction
reversible: true
is: SBO:0000176
is: R01281
name: serine palmitotransferase

http://identifiers.org/biomodels.db/BIOMD0000000471#_202a459c_bfbf_4d97_9bf9_e61004d6d3c2
stoichiometry: 1.0
species: meta s 0403
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_8408c83a_2bc4_49ac_841d_bdb14c758b09
units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0218
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#ede2af7c_9b9c_4089_ae95_6a5d41e39587
stoichiometry: 1.0
species: meta s 0700
type: SpeciesReference

meta e 0763
is: P04046
initial concentration: 0.001
initial amount: NaN
boundary condition: true
in compartment: meta cell
name: ADE4
is encoded by: S000004915
is encoded by: sce:YMR300C
constant: true
is: SBO:0000252
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#a062c40d_e607_4bef_b750_d76788156ee8
constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_7dac1d56_3f30_4107_9609_bc35dc7f9010
stoichiometry: 1.0
species: meta s 0432
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_3bb76fff_2f4b_477e_93f4_0d6c77e56e4c
units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1003
type: SpeciesReference

meta e 0273
boundary condition: true
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is: SBO:0000252
initial amount: NaN
in compartment: meta cell
is: P39518
is encoded by: S000000817
constant: true
type: Species
is encoded by: sce:YER015W
has only substance units: false
initial concentration: 0.001

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value: 0.00703639510095562
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#dbc98c5e_1bf1_4c88_82bc_f662ee2d6b8d
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#dd606949_0e14_4d23_99cb_bab43eb6aafa
stoichiometry: 1.0
species: meta s 1203
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_8363b806_55f1_413b_8f0f_4fbecf474ac5
value: 8.05209910738368E-5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_680e5770_d62c_4fcb_b0c7_51c88deb23ff
value: 0.010042233784859
type: LocalParameter

meta e 0761
name: LCB1
has only substance units: false
is encoded by: sce:YMR296C
constant: true
is: P25045
initial amount: NaN
in compartment: meta cell
is: SBO:0000252
type: Species
initial concentration: 0.001
boundary condition: true
is encoded by: S000004911

http://identifiers.org/biomodels.db/BIOMD0000000471#_4e190ea2_c155_493c_b623_fedbca83ad23
stoichiometry: 1.0
species: meta s 0018
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#f80d8543_17e7_4669_a719_37a605b5f5ce
units: dimensionless
value: 1.0
type: LocalParameter

meta r 0995
name: seryl-tRNA synthetase
is: SBO:0000176
fast: false
type: Reaction
reversible: true
is: R03662

http://identifiers.org/biomodels.db/BIOMD0000000471#_8b0d0f66_998a_4f01_a6f4_e0c2d58d9cf2
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_1a41405b_e5bb_4845_b536_1684dcb6d1e4
stoichiometry: 1.0
species: meta s 0981
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#ac9e577a_f504_4b44_a1b0_ee4f60d6ae9e
units: dimensionless
value: -1.0
type: LocalParameter

meta r 0996
reversible: true
fast: false
is: SBO:0000176
is: R02413
name: shikimate dehydrogenase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#c161b5cf_b8dc_494c_935d_84233ca8d6f0
stoichiometry: 1.0
species: meta s 1608
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#cf0a7933_a69c_47d5_8ba5_97923a685b2a
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#e288bdab_f153_4077_b9e4_ed5c48ac228c
stoichiometry: 1.0
species: meta s 1073
type: SpeciesReference

meta e 0910
boundary condition: true
is: Q02784
in compartment: meta cell
is encoded by: S000005980
initial amount: NaN
name: GRX5
initial concentration: 0.001
is: SBO:0000252
has only substance units: false
type: Species
is encoded by: sce:YPL059W
constant: true

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constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_73043b9b_93c9_4116_8802_b1d257dc35d6
stoichiometry: 0.3018
species: meta s 1591
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0373
type: SpeciesReference

meta e 0276
boundary condition: true
type: Species
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initial amount: NaN
is: P32263
name: PRO3
constant: true
is encoded by: sce:YER023W
is: SBO:0000252
initial concentration: 0.001
in compartment: meta cell
has only substance units: false

meta r 0446
is: R00943
type: Reaction
name: formate-tetrahydrofolate ligase
fast: false
is: SBO:0000176
reversible: true

meta s 1527
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constant: false
is: C03512
type: Species
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boundary condition: false
is: SBO:0000247
initial amount: NaN
is: CHEBI:29159
initial concentration: 0.1
has only substance units: false

meta e 0769
initial concentration: 0.001
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has only substance units: false
is: P53982
type: Species
constant: true
boundary condition: true
is encoded by: sce:YNL009W
is: SBO:0000252
initial amount: NaN
name: IDP3
is encoded by: S000004954

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value: 1.3575612338737E-4
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0849
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stoichiometry: 1.0
species: meta s 0302
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0522
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0999
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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0278
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initial amount: NaN
is encoded by: sce:YER026C
is: P08456
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initial concentration: 0.001
type: Species
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name: CHO1
boundary condition: true
constant: true
in compartment: meta cell

meta e 0765
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constant: true
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is: SBO:0000252
boundary condition: true
type: Species
is encoded by: S000004930
is: P40308
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_342ea941_16d3_40d3_b580_d6ff6afec6df
stoichiometry: 1.0
species: meta s 0557
type: SpeciesReference

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value: 0.00731344841399458
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 0.0112491235594554
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0587
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value: 0.231348466852626
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0764
type: SpeciesReference

meta r 0208
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is: SBO:0000176
type: Reaction
is: R01954
reversible: true
name: argininosuccinate synthase

meta r 0337
type: Reaction
reversible: true
name: diacylglycerol pyrophosphate phosphatase
is: SBO:0000176
fast: false

meta e 0167
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constant: true
type: Species
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name: GCV1
is: P48015
is: SBO:0000252
initial amount: NaN
boundary condition: true
initial concentration: 0.001
has only substance units: false
is encoded by: sce:YDR019C

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stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

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reversible: true
type: Reaction
fast: false
name: fatty acyl-CoA synthase (n-C8:0CoA), lumped reaction
is: SBO:0000176

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0180
type: SpeciesReference

meta e 0168
constant: true
name: SES1
in compartment: meta cell
is: P07284
type: Species
boundary condition: true
initial amount: NaN
initial concentration: 0.001
has only substance units: false
is encoded by: sce:YDR023W
is encoded by: S000002430
is: SBO:0000252

http://identifiers.org/biomodels.db/BIOMD0000000471#_1f7ea715_9da2_48e2_9adb_a06255626f31
units: dimensionless
value: -1.0
type: LocalParameter

meta r 0209
is: R03646
is: SBO:0000176
type: Reaction
fast: false
reversible: true
name: arginyl-tRNA synthetase

meta e 0390
is encoded by: sce:YGR185C
constant: true
in compartment: meta cell
name: TYS1
is encoded by: S000003417
boundary condition: true
initial concentration: 0.001
has only substance units: false
initial amount: NaN
is: SBO:0000252
type: Species
is: P36421

http://identifiers.org/biomodels.db/BIOMD0000000471#_3df1bde8_37ee_4d4a_8e59_46424bdff251
constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#a927fdd0_c353_4bfd_89ee_291b088a11e9
stoichiometry: 0.8079
species: meta s 1107
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_54202e35_3834_4093_ba80_87d977eb3cdc
units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0122
type: SpeciesReference

meta s 0304
has only substance units: false
boundary condition: false
constant: false
is: SBO:0000247
in compartment: meta cell
name: 5,10-methenyl-THF
initial amount: NaN
type: Species
is: CHEBI:57455
is: C00445
initial concentration: 0.1

meta e 0169
is encoded by: sce:YDR035W
in compartment: meta cell
is encoded by: S000002442
initial amount: NaN
initial concentration: 0.001
is: P14843
boundary condition: true
constant: true
type: Species
has only substance units: false
is: SBO:0000252
name: ARO3

http://identifiers.org/biomodels.db/BIOMD0000000471#db57d892_4878_45fc_aeb9_ae42782cca97
units: dimensionless
value: 1.0
type: LocalParameter

meta s 0301
in compartment: meta cell
initial concentration: 0.1
has only substance units: false
type: Species
is: CHEBI:58426
initial amount: NaN
is: C04376
name: 5'-phosphoribosyl-N-formylglycineamide
boundary condition: false
constant: false
is: SBO:0000247

meta r 1049
name: transketolase 1
is: SBO:0000176
type: Reaction
fast: false
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_0c0ddcf5_7ae4_4f90_b932_f0cc23d5513f
value: 0.0115748193375687
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1449
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0008
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#c958e0ff_0882_4261_9184_8ac500867f29
stoichiometry: 1.0
species: meta s 0745
type: SpeciesReference

meta r 0207
is: SBO:0000176
reversible: true
is: R01086
fast: false
type: Reaction
name: argininosuccinate lyase

meta r 0336
is: SBO:0000176
type: Reaction
name: diacylglycerol acyltransferase
fast: false
reversible: true

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constant: true
value: 0.1
type: Parameter

meta e 0392
is: SBO:0000252
initial concentration: 0.001
boundary condition: true
in compartment: meta cell
type: Species
has only substance units: false
is encoded by: S000003424
name: TDH3
initial amount: NaN
is encoded by: sce:YGR192C
constant: true
is: P00359

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value: 0.00400019441014414
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_8f73f749_829e_4dc0_86a0_4abae70a4503
stoichiometry: 1.0
species: meta s 1203
type: SpeciesReference

meta s 0302
name: 5'-phosphoribosyl-N-formylglycineamidine
constant: false
in compartment: meta cell
is: SBO:0000247
type: Species
is: C04640
initial amount: NaN
initial concentration: 0.1
has only substance units: false
is: CHEBI:58478
boundary condition: false

meta r 1048
is: SBO:0000176
reversible: true
name: transaldolase
fast: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#_2a935d82_6c8e_40c4_b7dc_12f1262331b0
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_1ec280d7_7927_4d87_8e9b_35ca5bc53bc6
stoichiometry: 1.0
species: meta s 1207
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#ccd61222_24f2_47f3_a152_34e082ef2b20
stoichiometry: 1.0
species: meta s 0745
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_1e00549f_f3a4_4664_9264_9fe67d8eab3e
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_83c99146_2f2f_4e15_9ef3_761cdb74b174
stoichiometry: 1.0
species: meta s 0423
type: SpeciesReference

meta r 0997
name: shikimate kinase
is: SBO:0000176
fast: false
is: R02412
type: Reaction
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000471#e17e6fa7_cbaf_4cb6_8535_0e1bb6ec5868
reversible: true
type: Reaction
fast: false
is: SBO:0000176
name: transketolase 2

http://identifiers.org/biomodels.db/BIOMD0000000471#_1752ad02_41d7_4279_9b0c_e717ffbe3b1f
stoichiometry: 1.0
species: meta s 1322
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_96d981fa_3c59_45e7_8b87_1a8ff7d1e26d
stoichiometry: 1.0
species: meta s 0209
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#db2f80f8_29dc_4c5a_9f40_bbc11d3ed2c7
value: 1.46007394609031
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_138511a7_6029_44a7_a740_be833a80f782
value: 5.86779635397514
type: LocalParameter

meta r 0563
is: SBO:0000176
fast: false
reversible: true
is: R04558
name: Imidazole-glycerol-3-phosphate synthase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#ac2c1520_c3b7_4b4a_acae_1abbf43bbb15
value: 2.88565330302391
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_5864000c_c5c2_48ec_a61e_e21258e1ff7f
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#c69db5cb_e694_4919_bc2b_3827cdbea3e8
units: dimensionless
value: 1.0
type: LocalParameter

meta s 0493
constant: false
name: ceramide-3 (C24)
boundary condition: false
type: Species
is: CHEBI:52373
is: SBO:0000247
has only substance units: false
initial concentration: 0.1
in compartment: meta cell
initial amount: NaN

meta s 0300
is: C03373
constant: false
initial concentration: 0.1
is: CHEBI:58592
has only substance units: false
in compartment: meta cell
boundary condition: false
type: Species
initial amount: NaN
name: 5'-phosphoribosyl-5-aminoimidazole
is: SBO:0000247

http://identifiers.org/biomodels.db/BIOMD0000000471#_9623bdc3_870c_4a93_be78_c51243caa6d4
units: dimensionless
value: -1.0
type: LocalParameter

meta s 0158
initial amount: NaN
boundary condition: false
is: SBO:0000247
is: CHEBI:50606
name: 2-hydroxy-3-oxobutyl phosphate
has only substance units: false
initial concentration: 0.1
in compartment: meta cell
constant: false
is: C15556
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000471#_5a03c687_4b69_473d_8401_cbb052eb7c2e
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_5f9b3118_6c93_4e90_b9a4_d85bbecb6c61
stoichiometry: 1.0
species: meta s 0662
type: SpeciesReference

meta r 0564
reversible: true
fast: false
type: Reaction
is: SBO:0000176
is: R03457
name: imidazoleglycerol-phosphate dehydratase

http://identifiers.org/biomodels.db/BIOMD0000000471#a00ff456_a48f_44f1_9e75_d903bbcbd6d9
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_80eabbe7_8fd3_4f0b_9d55_dcf2ba967270
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_2377a2e0_4211_4497_8edb_84438905289b
is: SBO:0000176
type: Reaction
fast: false
name: ornithine carbamoyltransferase
reversible: true

meta e 0165
is: P00912
in compartment: meta cell
constant: true
type: Species
is encoded by: sce:YDR007W
is: SBO:0000252
is encoded by: S000002414
boundary condition: true
has only substance units: false
initial amount: NaN
initial concentration: 0.001
name: TRP1

meta r 0202
type: Reaction
reversible: true
is: R01073
is: SBO:0000176
name: anthranilate phosphoribosyltransferase
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_754b30c6_caf6_4475_a96c_08bfe3cc9f43
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#a456ce30_e252_4130_b92c_bf48f7ebecd3
constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_310c1132_f2d7_4d75_a94c_81e8f9d12038
stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_6aea2e97_65ae_4ef7_aaac_7e3b6536ad7a
units: dimensionless
value: 1.0
type: LocalParameter

meta r 1045
fast: false
is: SBO:0000176
reversible: true
is: R02101
name: thymidylate synthase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#cb63c6ae_faed_42d9_bec3_5c4898ca1965
value: 0.0112491235594474
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_23ba4df7_69a3_4f4f_b9da_eb7d167dab6d
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#de89be5f_a148_4db6_b3d9_14a6ab083743
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_6db40d59_16f3_4357_8c61_8218fe203555
value: 0.00217467874480475
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#c550a68d_279f_46a2_b044_da67a5019901
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_00b9d808_7aa6_49dd_bc45_f638d29f39c2
stoichiometry: 1.0
species: meta s 0550
type: SpeciesReference

meta r 0203
fast: false
is: SBO:0000176
is: R00986
type: Reaction
name: anthranilate synthase
reversible: true

meta r 0891
is: R01513
fast: false
reversible: true
type: Reaction
name: phosphoglycerate dehydrogenase
is: SBO:0000176

http://identifiers.org/biomodels.db/BIOMD0000000471#_3e53d2b7_fb07_4ba6_a4d2_4c4c70e560af
stoichiometry: 1.0
species: meta s 1203
type: SpeciesReference

meta r 0352
is: R04441
type: Reaction
fast: false
name: dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)
is: SBO:0000176
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_00d5de93_c250_4dac_ade6_c3cd60e6092e
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_8e47874f_28c9_4e3c_855c_6038342d8210
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#fa093337_f051_459e_849b_9edb6a6edc50
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#ce46085c_df6c_4870_bde1_29aa9ee93724
stoichiometry: 1.0
species: meta s 1191
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_5afd95a4_7ac9_49e2_8846_0a10f6367b10
value: 0.00375691882979276
type: LocalParameter

meta r 0566
is: SBO:0000176
name: indole-3-glycerol-phosphate synthase
reversible: true
type: Reaction
is: R03508
fast: false

meta e 0186
initial amount: NaN
boundary condition: true
has only substance units: false
in compartment: meta cell
is encoded by: S000002565
name: HOM2
is: SBO:0000252
initial concentration: 0.001
is: P13663
is encoded by: sce:YDR158W
type: Species
constant: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_6984ed50_ca5a_40a1_92bd_4206eadad72b
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#d1b798e4_4b15_414c_93d3_134e92160059
value: 9.10860206851083E-5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_8a66cccc_360a_4496_97bc_0f8578c3bd32
value: 5.30955594768567E-4
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#a97ba33d_5967_4349_a7d7_b8e4d9587ba0
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#cc2e64ae_97ed_4c94_9d9a_6ede6e25a80e
constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_393fa326_78a3_4fe6_a272_0edd7adc74a4
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#a1c29457_abdc_400d_95d1_3403d1b4331c
value: 1.32100771565048E-12
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_2a25f092_753c_4c65_ad22_649870dc3270
value: 0.00187447440148675
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#cf04f604_0fe1_4ddc_8d0b_e1516a29b21c
stoichiometry: 1.0
species: meta s 0306
type: SpeciesReference

meta r 0565
name: IMP dehydrogenase
is: R01130
is: SBO:0000176
fast: false
reversible: true
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#_74128d1d_5c04_40b7_abd5_da4aa6e1091e
stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_45d634a1_e627_4761_831e_0534b53423f1
value: 0.0174126109618039
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_359f94ae_eee5_4198_8805_858106dd8fc4
stoichiometry: 1.0
species: meta s 0423
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#e62c7899_1a06_4a80_b391_950ef11cf2a2
units: dimensionless
value: -1.0
type: LocalParameter

meta r 0893
name: phosphoglycerate mutase
fast: false
reversible: true
is: R01518
type: Reaction
is: SBO:0000176

http://identifiers.org/biomodels.db/BIOMD0000000471#c95ef850_ef38_4771_a006_b12b78d580cd
units: dimensionless
value: 1.0
type: LocalParameter

meta r 0568
type: Reaction
name: inorganic diphosphatase
reversible: true
fast: false
is: SBO:0000176

meta e 0398
name: TRX2
is: SBO:0000252
boundary condition: true
initial amount: NaN
has only substance units: false
type: Species
constant: true
is encoded by: sce:YGR209C
is encoded by: S000003441
initial concentration: 0.001
in compartment: meta cell
is: P22803

meta r 0225
is: R01071
type: Reaction
reversible: true
name: ATP phosphoribosyltransferase
fast: false
is: SBO:0000176

http://identifiers.org/biomodels.db/BIOMD0000000471#_9ff7309a_2487_4920_8955_a81c610ef690
stoichiometry: 1.0
species: meta s 0526
type: SpeciesReference

meta r 0353
type: Reaction
name: dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)
is: SBO:0000176
is: R05070
reversible: true
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_6a232ed5_e0eb_4476_9ee4_1cb2dee340a2
units: dimensionless
value: 1.0
type: LocalParameter

meta r 0892
name: phosphoglycerate kinase
is: R01512
type: Reaction
fast: false
is: SBO:0000176
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_193c30d0_eab5_48f3_a58e_76c3e8a4dc08
units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_87687520_9861_4069_a98e_36d3532fe783
stoichiometry: 1.0
species: meta s 1270
type: SpeciesReference

meta s 0165
initial amount: NaN
is: C02631
in compartment: meta cell
initial concentration: 0.1
type: Species
boundary condition: false
constant: false
is: SBO:0000247
is: CHEBI:58085
name: 2-isopropylmaleic acid
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#b8dd2767_7a11_4698_b9f1_6ef2b6f3fac6
value: 0.00251625132250899
type: LocalParameter

meta e 0397
initial concentration: 0.001
in compartment: meta cell
constant: true
is encoded by: sce:YGR208W
is: SBO:0000252
boundary condition: true
initial amount: NaN
has only substance units: false
type: Species
name: SER2
is encoded by: S000003440
is: P42941

meta e 0396
is encoded by: sce:YGR204W
boundary condition: true
is encoded by: S000003436
has only substance units: false
name: ADE3
is: SBO:0000252
initial amount: NaN
initial concentration: 0.001
in compartment: meta cell
type: Species
constant: true
is: P07245

meta e 0182
is: SBO:0000252
in compartment: meta cell
is encoded by: sce:YDR127W
boundary condition: true
type: Species
has only substance units: false
initial amount: NaN
is: P08566
constant: true
initial concentration: 0.001
is encoded by: S000002534
name: ARO1

http://identifiers.org/biomodels.db/BIOMD0000000471#_697b1276_6e45_462d_abae_543e775b8ed3
stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_804917a3_78ce_4cdc_aa90_f5e6cdebb20f
units: dimensionless
value: 6.97E-4
type: LocalParameter

meta r 0355
name: dimethylallyltranstransferase
type: Reaction
is: R01658
is: SBO:0000176
reversible: true
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000471#c678bdc9_7fb3_42ac_b700_1c7e9db73081
value: 0.00179092669763194
type: LocalParameter

meta e 0181
is encoded by: sce:YDR098C
in compartment: meta cell
name: GRX3
type: Species
boundary condition: true
initial amount: NaN
is: Q03835
is: SBO:0000252
constant: true
has only substance units: false
is encoded by: S000002505
initial concentration: 0.001

http://identifiers.org/biomodels.db/BIOMD0000000471#_42dd377b_6f20_4ce8_812d_da10e6482ecb
units: dimensionless
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_83013020_d597_45e3_904d_9301a26945c7
units: dimensionless
value: -1.0
type: LocalParameter

meta s 0162
boundary condition: false
is: CHEBI:35129
is: C02504
initial concentration: 0.1
in compartment: meta cell
name: 2-isopropylmalate
initial amount: NaN
is: SBO:0000247
has only substance units: false
type: Species
constant: false

meta s 1399
type: Species
is: CHEBI:15361
boundary condition: false
constant: false
initial concentration: 0.1
initial amount: NaN
in compartment: meta cell
name: pyruvate
is: C00022
is: SBO:0000247
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_770c8a82_bb32_4908_b2c3_c70a8bff0007
value: 0.00609896813766758
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_11fed5fb_88a8_47b3_8966_944270a922ec
value: 2.59974684150501E-4
type: LocalParameter

meta r 0220
name: Aspartyl-tRNA synthetase
reversible: true
is: SBO:0000176
is: R05577
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000471#f26ebec3_ed45_4970_96db_0758bf2a6421
stoichiometry: 1.0
species: meta s 0764
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_7e1d02df_492b_4317_b918_9e86fc36480e
units: dimensionless
value: -4.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_88176d0d_65bc_4802_87c6_cee7dfa13ed4
constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_380e4724_2857_44b0_992a_42c93f500b84
value: 5.30955595806181E-4
type: LocalParameter

meta e 0393
in compartment: meta cell
initial amount: NaN
constant: true
is encoded by: S000003425
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stoichiometry: 1.0
species: meta s 0999
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units: dimensionless
value: 9.6E-5
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units: dimensionless
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meta s 0773
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meta e 0291
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boundary condition: true
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is encoded by: S000000872
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value: 0.0094001405938857
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stoichiometry: 1.0
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stoichiometry: 0.00288
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units: dimensionless
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units: dimensionless
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constant: false
initial concentration: 0.1
is: CHEBI:27689
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meta e 0290
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initial amount: NaN
is: Q01217
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boundary condition: true
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units: dimensionless
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meta r 0678
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is: SBO:0000176

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constant: true
value: 0.1
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units: dimensionless
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is: P23542
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constant: true
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type: Parameter

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value: 8.88088702058448E-4
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1212
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meta r 0467
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reversible: true
fast: false
type: Reaction
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is: R00771

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units: dimensionless
value: -1.0
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units: dimensionless
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value: 0.0112491235594474
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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0456
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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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value: 7.22995270761245E-5
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stoichiometry: 1.0
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stoichiometry: 1.0
species: meta s 0434
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meta s 1545
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units: dimensionless
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units: dimensionless
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meta e 0294
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boundary condition: true
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value: 0.00375691882979276
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units: dimensionless
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stoichiometry: 1.0
species: meta s 1576
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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0204
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stoichiometry: 2.0
species: meta s 1203
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http://identifiers.org/biomodels.db/BIOMD0000000471#_101758ed_46f5_4520_9b92_83430c47fe1c
units: dimensionless
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meta r 0674
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is: R00258
is: SBO:0000176

meta s 1543
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initial concentration: 0.1
initial amount: NaN
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boundary condition: false
is: C00029
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type: Species
is: CHEBI:58367

meta s 1286
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initial amount: NaN
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is: SBO:0000247
is: C00249
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name: palmitate
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units: dimensionless
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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
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meta e 0771
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stoichiometry: 2.0
species: meta s 1212
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meta s 0056
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type: Species
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is: SBO:0000247
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initial amount: NaN

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value: 2.94122930652654
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value: 4.80554664340808E-4
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stoichiometry: 1.0
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meta r 0462
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meta s 0991
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meta e 0774
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meta r 0792
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units: dimensionless
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stoichiometry: 1.0
species: meta s 1212
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units: dimensionless
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meta r 0570
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stoichiometry: 2.0
species: meta s 1207
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meta cell
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is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

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units: dimensionless
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meta e 0179
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constant: true
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name: TPS2
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is encoded by: sce:YDR074W
is: P31688
initial concentration: 0.001
type: Species

meta r 0349
is: SBO:0000176
is: R01993
reversible: true
fast: false
type: Reaction
name: dihydroorotase

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value: 0.168650639524106
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meta r 0096
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type: Reaction
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is: SBO:0000176

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units: dimensionless
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value: 1.33265490575614E-4
type: LocalParameter

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units: dimensionless
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stoichiometry: 1.0
species: meta s 1039
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meta r 1038
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type: Reaction
is: R02016
reversible: true
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is: SBO:0000176

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units: dimensionless
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stoichiometry: 1.0
species: meta s 0423
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stoichiometry: 1.0
species: meta s 1198
type: SpeciesReference

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units: dimensionless
value: 1.0
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units: dimensionless
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stoichiometry: 1.0
species: meta s 1275
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meta r 0097
type: Reaction
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is: SBO:0000176
is: R00006
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constant: true
value: 0.1
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constant: true
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units: dimensionless
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type: LocalParameter

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stoichiometry: 1.0
species: meta s 0991
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meta e 0177
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boundary condition: true
is: P40970
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is encoded by: S000002469
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type: Species
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meta r 0214
type: Reaction
is: R01397
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is: SBO:0000176
reversible: true

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constant: true
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type: Parameter

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constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#fb3a9627_a3a6_47c0_8c21_b6d27b5a5d3c
stoichiometry: 1.0
species: meta s 1322
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stoichiometry: 1.0
species: meta s 0322
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units: dimensionless
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units: dimensionless
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meta r 0215
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fast: false
is: R00480
is: SBO:0000176

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units: dimensionless
value: -1.0
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units: dimensionless
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units: dimensionless
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meta r 0216
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is: SBO:0000176
fast: false
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meta e 0175
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is: SBO:0000252
initial concentration: 0.001
has only substance units: false
is encoded by: sce:YDR050C
initial amount: NaN
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name: TPI1
is: P00942
type: Species
constant: true

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 0.2646
species: meta s 1561
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stoichiometry: 1.0
species: meta s 1386
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value: 8.05209910738368E-5
type: LocalParameter

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units: dimensionless
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units: dimensionless
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meta e 0176
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constant: true
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is encoded by: S000002465
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initial concentration: 0.001
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meta s 0481
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boundary condition: false
type: Species
has only substance units: false
is: SBO:0000247
is: CHEBI:52979
initial concentration: 0.1
initial amount: NaN
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name: ceramide-2 (C24)

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value: 0.0196783757273199
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value: 0.0524417011110143
type: LocalParameter

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units: dimensionless
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units: dimensionless
value: -1.0
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stoichiometry: 1.0
species: meta s 0456
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stoichiometry: 1.0
species: meta s 1364
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value: 8.05209911324267E-5
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1578
type: SpeciesReference

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constant: true
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type: Parameter

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stoichiometry: 1.0
species: meta s 0574
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meta s 0615
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has only substance units: false
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boundary condition: false
is: C00362
initial concentration: 0.1

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value: 0.00387115588138798
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units: dimensionless
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units: dimensionless
value: 1.0
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meta s 1379
initial concentration: 0.1
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name: Pro-tRNA(Pro)
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type: Species
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initial amount: NaN
boundary condition: false
in compartment: meta cell
is: CHEBI:29154
is: C02702

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0010
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units: dimensionless
value: -1.0
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meta r 0012
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fast: false
type: Reaction
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value: 0.00627317015230181
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1101
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units: dimensionless
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meta s 1590
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constant: false
boundary condition: false
initial amount: NaN
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name: tRNA(Gln)
is: SBO:0000247
is: CHEBI:29168

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stoichiometry: 1.0
species: meta s 0306
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units: dimensionless
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constant: true
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type: Parameter

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constant: true
value: 0.1
type: Parameter

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value: 0.00107785124523996
type: LocalParameter

meta s 0613
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name: dGDP
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is: CHEBI:58595
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is: C00361
type: Species
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units: dimensionless
value: -1.0
type: LocalParameter

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value: 3.75729835487922E-5
type: LocalParameter

meta r 0015
is: R09376
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reversible: true
type: Reaction
is: SBO:0000176

meta s 1377
is: C00254
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type: Species
is: SBO:0000247
constant: false
is: CHEBI:29934
boundary condition: false
initial amount: NaN
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initial concentration: 0.1

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is: SBO:0000185
fast: false
reversible: false
name: CO2 transport
type: Reaction

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value: 0.0115748193382789
type: LocalParameter

meta r 0014
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fast: false
reversible: true
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#_947cccbf_8ccb_48fe_b9aa_e0056f461dca
units: dimensionless
value: 1.0
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units: dimensionless
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value: 0.00965062714996943
type: LocalParameter

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units: dimensionless
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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0757
type: SpeciesReference

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constant: true
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type: Parameter

meta s 1593
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constant: false
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initial concentration: 0.1
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is: CHEBI:29176
initial amount: NaN
is: C01642
name: tRNA(Gly)

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units: dimensionless
value: 1.0
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meta e 0045
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is: P38221
initial concentration: 0.001
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is encoded by: S000000233
type: Species
constant: true
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initial amount: NaN
boundary condition: true
is: SBO:0000252
has only substance units: false

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stoichiometry: 1.0
species: meta s 0066
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 1594
type: Species
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is version of: CHEBI:29178
constant: false
name: tRNA(His)
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initial amount: NaN

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stoichiometry: 1.0
species: meta s 0841
type: SpeciesReference

meta r 0016
reversible: true
fast: false
name: 2-aceto-2-hydroxybutanoate synthase
type: Reaction
is: R08648
is: SBO:0000176

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 1029
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is: C00073
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boundary condition: false
name: L-methionine
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constant: false
initial amount: NaN
is: CHEBI:16643

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stoichiometry: 1.0
species: meta s 0325
type: SpeciesReference

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value: 0.00217467874388578
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0619
type: SpeciesReference

meta s 1591
is version of: CHEBI:29175
initial amount: NaN
name: tRNA(Glu)
in compartment: meta cell
type: Species
boundary condition: false
is: SBO:0000247
constant: false
initial concentration: 0.1
has only substance units: false

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units: dimensionless
value: 3.0
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units: dimensionless
value: 1.0
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constant: true
value: 0.1
type: Parameter

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value: 1.33265490575614E-4
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1025
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

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units: dimensionless
value: 2.0
type: LocalParameter

meta r 0018
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reversible: true
fast: false
is: R01939
type: Reaction
is: SBO:0000176

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1561
type: SpeciesReference

meta r 0661
type: Reaction
is: SBO:0000176
is: R00267
name: isocitrate dehydrogenase (NADP+), peroxisomal
fast: false
reversible: true

meta e 0329
constant: true
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is encoded by: sce:YGL012W
name: ERG4
boundary condition: true
is encoded by: S000002980
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initial concentration: 0.001
type: Species
initial amount: NaN
is: SBO:0000252

http://identifiers.org/biomodels.db/BIOMD0000000471#_7679ba6d_b5a6_4137_b177_ff6186001c54
stoichiometry: 1.0
species: meta s 0991
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#d84fee55_cf52_4ea1_a05a_0166596d686f
stoichiometry: 1.0
species: meta s 0666
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#bac55480_cc60_4256_8489_b3b54c26dac4
stoichiometry: 1.0
species: meta s 1607
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
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meta e 0328
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is: SBO:0000252
has only substance units: false
is encoded by: sce:YGL009C
boundary condition: true
is encoded by: S000002977
is: P07264
constant: true
in compartment: meta cell
initial concentration: 0.001
type: Species
initial amount: NaN

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1003
type: SpeciesReference

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value: 0.00625077817220527
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0619
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 0.892327912279146
type: LocalParameter

meta e 0325
is: P04806
is encoded by: S000001949
boundary condition: true
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is encoded by: sce:YFR053C
initial concentration: 0.001
is: SBO:0000252
constant: true
initial amount: NaN
type: Species
in compartment: meta cell
has only substance units: false

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0326
type: Species
initial amount: NaN
name: ERG26
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is encoded by: S000002969
is: SBO:0000252
boundary condition: true
is encoded by: sce:YGL001C
is: P53199
in compartment: meta cell
constant: true
initial concentration: 0.001

meta r 0118
fast: false
is: R02283
type: Reaction
reversible: true
is: SBO:0000176
name: acteylornithine transaminase

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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#fe7ac9ed_4e58_4186_bbe2_86d1a95374fe
stoichiometry: 1.0
species: meta s 1212
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_65e8dcb7_c0a2_4713_823d_24d374b94cbc
stoichiometry: 3.2E-5
species: meta s 1059
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#d111a245_3995_4766_833c_05d91d971fab
stoichiometry: 1.0
species: meta s 1212
type: SpeciesReference

meta s 0619
boundary condition: false
in compartment: meta cell
initial amount: NaN
initial concentration: 0.1
has only substance units: false
is: CHEBI:18035
is: C00165
is: SBO:0000247
type: Species
name: diglyceride
constant: false

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 0980
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constant: false
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is: SBO:0000247
type: Species
name: L-cystathionine
is: CHEBI:17482
has only substance units: false
boundary condition: false
is: C02291
initial amount: NaN

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1266
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_4b73c701_6ddd_4b70_a048_5cae463f3e22
name: C-4 methyl sterol oxidase
is: SBO:0000176
type: Reaction
reversible: true
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000471#e16389d2_387c_4c8b_ac5f_4297d0051dc0
stoichiometry: 1.0
species: meta s 0165
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0456
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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value: 0.00155984810490301
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1322
type: SpeciesReference

meta s 0981
in compartment: meta cell
is: SBO:0000247
type: Species
has only substance units: false
is: C00097
name: L-cysteine
initial amount: NaN
initial concentration: 0.1
constant: false
boundary condition: false
is: CHEBI:17561

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1101
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0456
type: SpeciesReference

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units: dimensionless
value: 0.8079
type: LocalParameter

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value: 0.0188389294905409
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0456
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 3.75729835487922E-5
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0973
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0767
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0394
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

meta s 1445
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in compartment: meta cell
type: Species
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is: C00836
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boundary condition: false
is: SBO:0000247
initial concentration: 0.1
constant: false
name: sphinganine

meta e 0472
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constant: true
is encoded by: S000001356
initial amount: NaN
type: Species
is: P40495
is encoded by: sce:YIL094C
name: LYS12
initial concentration: 0.001
in compartment: meta cell
boundary condition: true
is: SBO:0000252

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constant: true
value: 0.1
type: Parameter

meta s 0076
type: Species
has only substance units: false
initial amount: NaN
name: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
is: C01302
in compartment: meta cell
is: CHEBI:58613
initial concentration: 0.1
boundary condition: false
is: SBO:0000247
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000471#_1d903c46_2d9f_4ed9_b4ef_2ae842b66fc3
units: dimensionless
value: 1.0
type: LocalParameter

meta e 0320
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has only substance units: false
is encoded by: S000001921
boundary condition: true
initial concentration: 0.001
in compartment: meta cell
type: Species
name: HIS2
constant: true
is encoded by: sce:YFR025C
is: P38635
initial amount: NaN

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constant: true
value: 0.1
type: Parameter

meta s 0077
boundary condition: false
name: 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide
in compartment: meta cell
initial concentration: 0.1
is: CHEBI:58435
is: C04896
is: SBO:0000247
constant: false
type: Species
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000471#_2bf81980_f1f4_4c5b_b602_3327ac586d8f
stoichiometry: 1.0
species: meta s 1275
type: SpeciesReference

meta r 0361
reversible: true
name: dolichyl-phosphate D-mannosyltransferase
is: R01009
is: SBO:0000176
fast: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000471#b044247a_98cd_4162_a6c7_d29b4c736095
stoichiometry: 1.0
species: meta s 1591
type: SpeciesReference

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stoichiometry: 3.0
species: meta s 1212
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

meta e 0470
type: Species
name: THS1
initial concentration: 0.001
boundary condition: true
has only substance units: false
is: SBO:0000252
is encoded by: S000001340
constant: true
initial amount: NaN
is: P04801
in compartment: meta cell
is encoded by: sce:YIL078W

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value: 0.00192419218780178
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1416
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_16b95ac9_e5de_4e82_ad3f_3c96a273ef21
name: mmol
type: SBMLUnitsDef

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stoichiometry: 1.0
species: meta s 1039
type: SpeciesReference

meta s 0973
boundary condition: false
name: L-aspartate
initial concentration: 0.1
has only substance units: false
constant: false
in compartment: meta cell
is: CHEBI:29991
type: Species
is: C00049
initial amount: NaN
is: SBO:0000247

http://identifiers.org/biomodels.db/BIOMD0000000471#_804bae12_78b9_4542_8b89_1707133e37c8
stoichiometry: 1.0
species: meta s 0259
type: SpeciesReference

meta s 0075
initial concentration: 0.1
in compartment: meta cell
initial amount: NaN
is: C00236
is: CHEBI:57604
has only substance units: false
is: SBO:0000247
constant: false
type: Species
boundary condition: false
name: 1,3-bisphospho-D-glycerate

meta s 0291
constant: false
in compartment: meta cell
is: CHEBI:17865
has only substance units: false
is: C00233
name: 4-methyl-2-oxopentanoate
type: Species
is: SBO:0000247
boundary condition: false
initial amount: NaN
initial concentration: 0.1

meta r 0502
type: Reaction
is: SBO:0000176
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reversible: true
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meta r 0008
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meta s 1598
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boundary condition: false
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stoichiometry: 1.0
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stoichiometry: 1.0
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meta r 0231
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meta s 0979
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value: 0.00250816743817059
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units: dimensionless
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stoichiometry: 1.0
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meta s 1596
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constant: true
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units: dimensionless
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meta s 0299
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constant: false
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meta e 0077
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units: dimensionless
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stoichiometry: 1.0
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units: dimensionless
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meta r 0939
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meta e 0476
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initial amount: NaN
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boundary condition: false
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stoichiometry: 1.0
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meta s 1021
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type: Species
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name: CTP synthase (NH3)
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units: dimensionless
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meta e 0071
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units: dimensionless
value: 1.0
type: LocalParameter

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value: 0.00375691882979276
type: LocalParameter

meta r 0364
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fast: false
name: dUTP diphosphatase
type: Reaction
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stoichiometry: 1.0
species: meta s 0394
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stoichiometry: 1.0
species: meta s 0832
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constant: true
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value: 0.0188389294905409
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meta r 0658
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is: SBO:0000176
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meta r 0236
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name: C-3 sterol keto reductase (4-methylzymosterol)
type: Reaction
is: SBO:0000176
fast: false

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stoichiometry: 1.0
species: meta s 0999
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stoichiometry: 1.0
species: meta s 0456
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stoichiometry: 1.0
species: meta s 0458
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units: dimensionless
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units: dimensionless
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boundary condition: false
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type: Species
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units: dimensionless
value: 1.0
type: LocalParameter

meta r 0938
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type: Reaction
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name: prephenate dehydratase
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reversible: true

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value: 0.0386660157978829
type: LocalParameter

meta e 0475
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type: Species
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initial concentration: 0.001
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type: Species
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is: SBO:0000247
is: CHEBI:30407
in compartment: meta cell
initial amount: NaN
is: C03082
constant: false
name: 4-phospho-L-aspartate

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constant: true
value: 0.1
type: Parameter

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value: 0.00217467874479323
type: LocalParameter

meta r 0366
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type: Reaction
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reversible: true
is: SBO:0000176

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 0625
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boundary condition: false
initial concentration: 0.1
is: C00415
type: Species
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is: CHEBI:57451
initial amount: NaN
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meta r 0024
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meta e 0031
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meta e 0057
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value: 0.00609896813767666
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meta s 1039
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type: Species
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value: 0.00209877372752306
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meta r 0941
reversible: true
type: Reaction
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stoichiometry: 1.0
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meta e 0030
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units: dimensionless
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units: dimensionless
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value: 2.56065575909038E-4
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meta r 0029
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meta e 0054
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meta s 1238
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stoichiometry: 1.0
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units: dimensionless
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units: dimensionless
value: 1.0
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stoichiometry: 0.0507
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value: 5.83975250367414E-4
type: LocalParameter

meta r 0023
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type: Reaction
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meta s 0629
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boundary condition: false
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BIOMD0000000471
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species: meta s 1408
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species: meta s 1612
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species: meta s 1577
species: meta e 0757
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reaction: meta r 0353
species: meta s 1048
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species: meta s 1270
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reaction: meta r 0154
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species: meta e 0613
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reaction: meta r 0901
species: meta e 0515
species: meta s 1578
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species: meta s 1233
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reaction: meta r 0538
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species: meta e 0805
species: meta s 1014
species: meta s 1010
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meta e 0038
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meta s 1233
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stoichiometry: 1.0
species: meta s 1212
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value: 0.00609896813766667
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value: 0.0112491235594566
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value: 2.56634863390825E-4
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value: 0.0306618317263325
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meta r 0020
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constant: true
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type: Parameter

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stoichiometry: 1.0
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value: 9.10860206737184E-5
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value: 0.00609896813766667
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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 0.0386660157978829
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value: 0.00419754745504612
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meta r 0241
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is: R07509
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meta s 0965
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name: L-arginine
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constant: false
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initial concentration: 0.1

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units: dimensionless
value: 2.0
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meta e 0334
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is: P11154
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stoichiometry: 0.1017
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stoichiometry: 1.0
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value: 1.02210849818021E-5
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meta s 1035
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units: dimensionless
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meta r 0244
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type: Reaction
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stoichiometry: 1.0
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meta e 0065
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is encoded by: sce:YBR126C
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units: dimensionless
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stoichiometry: 1.0
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meta s 0969
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type: Species
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name: L-asparagine

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units: dimensionless
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meta e 0062
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is encoded by: sce:YBR115C
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constant: true
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meta e 0063
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meta s 0409
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meta r 0243
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stoichiometry: 1.0
species: meta s 0456
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meta s 0404
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is: CHEBI:17732
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constant: false

meta s 0061
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in compartment: meta cell
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is: C00337
constant: false
is: CHEBI:30864
initial amount: NaN

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value: 5.83975250368712E-4
type: LocalParameter

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value: 3.75729835487922E-5
type: LocalParameter

meta e 0489
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is encoded by: S000001473
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initial concentration: 0.001
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constant: true
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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 1161
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units: dimensionless
value: 0.046
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value: 0.00217467874480475
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meta s 1032
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is: SBO:0000247
is: CHEBI:17295
initial amount: NaN
is: C00079
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type: Species
constant: false
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constant: true
value: 0.1
type: Parameter

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value: 2.58760203874159E-4
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meta e 0594
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constant: true
boundary condition: true
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is: P28272
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value: 0.231348466852626
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stoichiometry: 1.0
species: meta s 0475
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value: 0.00155984810490327
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units: dimensionless
value: 1.1348
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is encoded by: sce:YBL011W
is: P32784
boundary condition: true
initial concentration: 0.001

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units: dimensionless
value: -1.0
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stoichiometry: 1.0
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units: dimensionless
value: -1.0
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value: -1.0
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stoichiometry: 1.0
species: meta s 1543
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constant: true
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stoichiometry: 1.0
species: meta s 0980
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scale: -3
multipler: 1.0
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constant: true
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stoichiometry: 1.0
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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
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stoichiometry: 1.0
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constant: true
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stoichiometry: 1.0
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meta s 1006
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value: 0.00251625132250899
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meta r 0039
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units: dimensionless
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stoichiometry: 1.0
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constant: true
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stoichiometry: 1.0
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stoichiometry: 1.0
species: meta s 0951
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value: 0.0306618317263326
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meta e 0022
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boundary condition: true
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stoichiometry: 1.0
species: meta s 0581
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meta r 0038
is: SBO:0000176
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type: Reaction
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units: dimensionless
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units: dimensionless
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stoichiometry: 1.0
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meta e 0029
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meta r 0032
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type: Reaction
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stoichiometry: 1.0
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meta e 0028
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initial concentration: 0.001
is: SBO:0000252
type: Species
is encoded by: S000003159
constant: true
boundary condition: true
has only substance units: false
is encoded by: sce:YGL191W
name: COX13

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0314
type: SpeciesReference

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value: 2.3107859282821E-4
type: LocalParameter

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units: dimensionless
value: 0.1017
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

meta e 0348
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is: P53090
type: Species
initial amount: NaN
initial concentration: 0.001
constant: true
name: ARO8
is encoded by: S000003170
boundary condition: true
is encoded by: sce:YGL202W
has only substance units: false
is: SBO:0000252

meta r 0250
name: carbamoyl-phosphate synthase (glutamine-hydrolysing)
is: SBO:0000176
reversible: true
fast: false
type: Reaction
is: R00575

http://identifiers.org/biomodels.db/BIOMD0000000471#_26628f22_0f29_4f59_a562_7cc6b3ab86a3
value: 0.0386660157978829
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 1192
type: SpeciesReference

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value: 1.2998734207478E-4
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 0951
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is: SBO:0000247
initial concentration: 0.1
has only substance units: false
is: C00166
in compartment: meta cell
is: CHEBI:18005
boundary condition: false
type: Species

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units: dimensionless
value: 2.0
type: LocalParameter

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units: dimensionless
value: -2.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1524
type: SpeciesReference

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value: 0.0658655350433608
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0722
type: SpeciesReference

meta e 0346
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initial amount: NaN
type: Species
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initial concentration: 0.001
is: SBO:0000252
boundary condition: true
is encoded by: sce:YGL187C
has only substance units: false

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stoichiometry: 1.0
species: meta s 0629
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0188
type: SpeciesReference

meta s 0953
initial amount: NaN
name: L-2-aminoadipate
is: SBO:0000247
is: CHEBI:58672
is: C00956
initial concentration: 0.1
has only substance units: false
constant: false
type: Species
in compartment: meta cell
boundary condition: false

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 9.9E-4
species: meta s 1405
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0419
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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stoichiometry: 1.0
species: meta s 0568
type: SpeciesReference

meta e 0090
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has only substance units: false
type: Species
is: P38145
initial amount: NaN
constant: true
is encoded by: S000000460
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is: SBO:0000252
name: RIB5
boundary condition: true
initial concentration: 0.001

meta e 0343
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is: SBO:0000252
type: Species
is: P50113
constant: true
name: LYS5
initial amount: NaN
boundary condition: true
initial concentration: 0.001
has only substance units: false
is encoded by: S000003122
is encoded by: sce:YGL154C

meta s 1469
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is: C11481
initial concentration: 0.1
type: Species
constant: false
boundary condition: false
name: sulphite
initial amount: NaN
is: SBO:0000247
has only substance units: false
is: CHEBI:17137

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0959
type: SpeciesReference

meta e 0091
type: Species
initial amount: NaN
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is: SBO:0000252
name: SHM1
is encoded by: sce:YBR263W
initial concentration: 0.001
boundary condition: true
constant: true
is: P37292
has only substance units: false
is encoded by: S000000467

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units: dimensionless
value: -1.0
type: LocalParameter

meta r 0528
name: guanylate kinase
is: R00332
is: SBO:0000176
reversible: true
fast: false
type: Reaction

meta s 1468
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is: SBO:0000247
has only substance units: false
constant: true
initial concentration: 1.0
is: CHEBI:16189
type: Species
is: C00059
boundary condition: true
name: sulphate
initial amount: NaN

meta s 1153
initial amount: NaN
name: myo-inositol
boundary condition: false
initial concentration: 0.1
is: CHEBI:17268
is: SBO:0000247
has only substance units: false
in compartment: meta cell
type: Species
constant: false
is: C00137

meta e 0092
initial concentration: 0.001
boundary condition: true
initial amount: NaN
type: Species
is encoded by: sce:YBR265W
has only substance units: false
constant: true
is: SBO:0000252
is encoded by: S000000469
in compartment: meta cell
name: TSC10
is: P38342

http://identifiers.org/biomodels.db/BIOMD0000000471#ea01f8f1_238f_4b0e_8d7f_93ce6d406ae2
units: dimensionless
value: 6.0
type: LocalParameter

meta r 0525
type: Reaction
fast: false
is: R00425
name: GTP cyclohydrolase II
reversible: true
is: SBO:0000176

http://identifiers.org/biomodels.db/BIOMD0000000471#c33e633a_28d7_4920_94ea_c2547893091f
value: 0.0100308480322675
type: LocalParameter

meta s 1467
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boundary condition: false
is: CHEBI:16189
has only substance units: false
name: sulphate
constant: false
is: SBO:0000247
initial concentration: 0.1
initial amount: NaN
type: Species
in compartment: meta cell

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constant: true
value: 0.1
type: Parameter

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value: 2.88565330302391
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

meta r 0499
name: glycinamide ribotide transformylase
is: SBO:0000176
is: R04325
reversible: true
type: Reaction
fast: false

meta e 0342
is encoded by: S000003116
is encoded by: sce:YGL148W
type: Species
in compartment: meta cell
is: SBO:0000252
boundary condition: true
initial amount: NaN
has only substance units: false
initial concentration: 0.001
name: ARO2
is: P28777
constant: true

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 1579
is: SBO:0000247
type: Species
initial concentration: 0.1
initial amount: NaN
has only substance units: false
boundary condition: false
is: CHEBI:52386
in compartment: meta cell
name: zymosterol intermediate 2
constant: false

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constant: true
value: 0.1
type: Parameter

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value: 1.46007394609031
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#c50cfb8e_9e5e_4966_8942_56e191ead37f
stoichiometry: 1.0
species: meta s 0056
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#cb02e58c_629c_49c8_9f43_fa78c3d98ca1
stoichiometry: 1.0
species: meta s 1606
type: SpeciesReference

meta r 1089
type: Reaction
is: SBO:0000176
fast: false
name: valyl-tRNA synthetase
reversible: true
is: R03665

http://identifiers.org/biomodels.db/BIOMD0000000471#_12c81ea1_3e6a_421d_af66_d321fb27a10b
units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1322
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_0d4be35f_72bc_41f3_a076_f59e3267db2d
stoichiometry: 1.0
species: meta s 0991
type: SpeciesReference

meta s 1578
initial concentration: 0.1
type: Species
initial amount: NaN
name: zymosterol intermediate 1c
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constant: false
boundary condition: false
is: SBO:0000247
has only substance units: false
is: CHEBI:52389

meta e 0452
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initial amount: NaN
type: Species
name: DCD1
is: SBO:0000252
initial concentration: 0.001
constant: true
has only substance units: false
is: P06773
in compartment: meta cell
is encoded by: sce:YHR144C
boundary condition: true

http://identifiers.org/biomodels.db/BIOMD0000000471#_8581c81f_81d7_4252_a6ea_16fce65854db
constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_08dbbce9_91b7_43f3_829b_d6a253d4ed25
stoichiometry: 1.0
species: meta s 1545
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_46517be5_f018_49ea_9955_3b66e1de39a8
constant: true
value: 0.1
type: Parameter

meta s 0959
is: C04076
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has only substance units: false
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name: L-allysine
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is: SBO:0000247
is: CHEBI:17917
initial concentration: 0.1
constant: false
initial amount: NaN

meta s 1577
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initial amount: NaN
is: SBO:0000247
in compartment: meta cell
constant: false
initial concentration: 0.1
boundary condition: false
is: CHEBI:52615
type: Species
name: zymosterol intermediate 1b

meta e 0340
is encoded by: S000003093
type: Species
constant: true
initial amount: NaN
boundary condition: true
is: P53128
is: SBO:0000252
has only substance units: false
is encoded by: sce:YGL125W
name: MET13
initial concentration: 0.001
in compartment: meta cell

meta s 1351
is: C00350
name: phosphatidylethanolamine
type: Species
in compartment: meta cell
constant: false
is: CHEBI:16038
has only substance units: false
initial amount: NaN
boundary condition: false
is: SBO:0000247
initial concentration: 0.1

meta r 0259
is: SBO:0000176
fast: false
type: Reaction
name: ceramide-1 hydroxylase (24C)
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000471#fabd6c08_ec9a_430c_8b6c_ce8e5ed7ba92
units: dimensionless
value: -3.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1610
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 1579
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

meta s 1576
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initial amount: NaN
boundary condition: false
is: SBO:0000247
initial concentration: 0.1
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constant: false
is: CHEBI:52388
type: Species

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stoichiometry: 1.0
species: meta s 1203
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 1.51989569594335
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

meta r 0495
type: Reaction
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is: SBO:0000176
fast: false
is: R00851

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 5.19949368301002E-4
type: LocalParameter

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fast: false
reversible: true
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is: SBO:0000176
type: Reaction

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1322
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1065
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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0456
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type: Species
initial concentration: 0.001
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is encoded by: sce:YHR190W
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is: SBO:0000252
name: ERG9
constant: true
initial amount: NaN
boundary condition: true
in compartment: meta cell

meta e 0458
type: Species
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is: P38697
is encoded by: S000001259
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has only substance units: false
initial amount: NaN
name: IMD2
boundary condition: true
is encoded by: sce:YHR216W
is: SBO:0000252

meta r 1084
type: Reaction
fast: false
reversible: true
is: SBO:0000176
name: UTP-glucose-1-phosphate uridylyltransferase
is: R00289

meta s 0955
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is: SBO:0000247
boundary condition: false
in compartment: meta cell
type: Species
name: L-alanine
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constant: false
is: CHEBI:16977
is: C00041
initial concentration: 0.1

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units: dimensionless
value: 0.1054
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 0.0112491235594486
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0654
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meta e 0457
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is: SBO:0000252
name: BAT1
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initial amount: NaN
boundary condition: true
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is encoded by: sce:YHR208W
is encoded by: S000001251
type: Species
initial concentration: 0.001
constant: true

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stoichiometry: 1.0
species: meta s 0785
type: SpeciesReference

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value: 1.69142241294296
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0999
type: SpeciesReference

meta r 1087
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fast: false
is: SBO:0000176
name: valine transaminase
is: R01214
type: Reaction

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value: 0.00217467874480193
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0551
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value: 0.00731344841399218
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0529
type: SpeciesReference

meta e 0454
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type: Species
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boundary condition: true
is encoded by: S000001217
is: SBO:0000252
constant: true
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is: P00925
initial amount: NaN
is encoded by: sce:YHR174W
name: ENO2

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stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

meta r 0491
name: glycerol-3-phosphate dehydrogenase (NAD)
fast: false
type: Reaction
is: R00842
is: SBO:0000176
reversible: true

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units: dimensionless
value: -1.0
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units: dimensionless
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constant: true
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stoichiometry: 1.0
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units: dimensionless
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meta r 0257
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value: 3.06632551696157E-5
type: LocalParameter

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stoichiometry: 0.001583
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stoichiometry: 1.0
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value: 1.46007394609031
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value: 0.00419754745504612
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stoichiometry: 0.3018
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stoichiometry: 1.0
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meta r 0968
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meta e 0582
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units: dimensionless
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stoichiometry: 1.0
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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

meta r 0967
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is: SBO:0000176
fast: false
is: R04457
type: Reaction

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value: 0.00609896813766667
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units: dimensionless
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meta e 0011
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meta r 0962
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is: R00200
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stoichiometry: 0.0036
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value: 0.00508184090624576
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units: dimensionless
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species: meta s 0953
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units: dimensionless
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meta s 1366
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constant: true
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units: dimensionless
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meta r 0961
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stoichiometry: 1.0
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meta e 0010
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units: dimensionless
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stoichiometry: 1.0
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stoichiometry: 1.0
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units: dimensionless
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stoichiometry: 1.0
species: meta s 0764
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meta e 0012
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boundary condition: true
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constant: true
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meta s 0602
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type: Species
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meta e 0802
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boundary condition: true

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stoichiometry: 1.0
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units: dimensionless
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meta r 0108
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meta e 0800
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units: dimensionless
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meta e 0017
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meta e 0016
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meta r 0041
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meta e 0586
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units: dimensionless
value: -1.0
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units: dimensionless
value: 1.0
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meta r 0040
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is: R03083
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is: SBO:0000176

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value: 2.48095549098117E-4
type: LocalParameter

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stoichiometry: 0.1914
species: meta s 1608
type: SpeciesReference

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value: 0.0350981004584189
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stoichiometry: 1.0
species: meta s 1198
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initial amount: NaN
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constant: true
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type: Species
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initial concentration: 0.001
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value: 5.83975250318604E-4
type: LocalParameter

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stoichiometry: 2.0
species: meta s 1207
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1045
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units: dimensionless
value: -1.0
type: LocalParameter

meta r 0393
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reversible: true
type: Reaction
is: SBO:0000176

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stoichiometry: 1.0
species: meta s 1187
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stoichiometry: 1.0
species: meta s 1377
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0423
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units: dimensionless
value: -3.0
type: LocalParameter

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value: 0.0112908713189552
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units: dimensionless
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units: dimensionless
value: -2.0
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units: dimensionless
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species: meta s 0456
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stoichiometry: 1.0
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units: dimensionless
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constant: false
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units: dimensionless
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meta e 0196
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boundary condition: true
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type: Species
initial concentration: 0.001
is: SBO:0000252

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constant: true
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units: dimensionless
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type: Species
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is: C00448
constant: false

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constant: true
value: 0.1
type: Parameter

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value: 0.00107785124523716
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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0836
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meta r 0110
type: Reaction
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is: SBO:0000176
name: acetyl-CoA hydrolase
reversible: true

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value: 0.0112491235594474
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meta s 0086
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is: CHEBI:60820
is: SBO:0000247
is: C03506
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type: Species
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initial concentration: 0.1
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constant: false
name: 1-C-(indol-3-yl)glycerol 3-phosphate

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stoichiometry: 1.0
species: meta s 0739
type: SpeciesReference

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stoichiometry: 3.0
species: meta s 1212
type: SpeciesReference

meta e 0353
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boundary condition: true
initial amount: NaN
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is: P46655
name: GUS1
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is encoded by: S000003214
is encoded by: sce:YGL245W
is: SBO:0000252
constant: true

meta r 0115
type: Reaction
is: R02649
name: acetylglutamate kinase
is: SBO:0000176
fast: false
reversible: true

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stoichiometry: 1.0
species: meta s 0180
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stoichiometry: 1.0
species: meta s 1386
type: SpeciesReference

meta r 0514
is: R01231
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is: SBO:0000176
reversible: true
type: Reaction
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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0194
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is: SBO:0000252
initial amount: NaN
type: Species
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boundary condition: true
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constant: true
initial concentration: 0.001
is encoded by: S000002634
is: P07170
is encoded by: sce:YDR226W

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value: 0.087517608841966
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0078
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
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meta e 0355
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constant: true
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initial concentration: 0.001
is encoded by: sce:YGL253W
boundary condition: true
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is encoded by: S000003222
is: P04807
type: Species
has only substance units: false
initial amount: NaN

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stoichiometry: 1.0
species: meta s 0291
type: SpeciesReference

meta s 1255
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name: octanoyl-CoA
initial concentration: 0.1
in compartment: meta cell
is: C01944
boundary condition: false
initial amount: NaN
is: SBO:0000247
is: CHEBI:57386

http://identifiers.org/biomodels.db/BIOMD0000000471#_36dd45b8_240d_44b1_b8f6_3e66d579df69
value: 5.19949368301002E-4
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0423
type: SpeciesReference

meta s 0089
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name: 1-phosphatidyl-1D-myo-inositol
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constant: false
is: C01194
initial amount: NaN
is: SBO:0000247
initial concentration: 0.1
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000471#_870f391d_d7d1_46f1_8cc1_88435264cb54
stoichiometry: 1.0
species: meta s 1589
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#_29f657b4_41a5_40db_81bd_406d82199768
stoichiometry: 1.0
species: meta s 0394
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0581
type: SpeciesReference

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value: 1.36629031036409E-4
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 1.36629031089924E-4
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000471#f92344ae_b3e4_499b_95e5_053ccad3482f
fast: false
reversible: true
name: sulfite reductase (NADPH2)
type: Reaction
is: SBO:0000176

meta e 0084
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is: SBO:0000252
initial concentration: 0.001
boundary condition: true
type: Species
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in compartment: meta cell
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initial amount: NaN
constant: true
is encoded by: sce:YBR218C

meta s 0082
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name: 1-acyl-sn-glycerol 3-phosphate
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is: C00681
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initial concentration: 0.1
is: SBO:0000247
initial amount: NaN
type: Species
boundary condition: false

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stoichiometry: 1.0
species: meta s 0373
type: SpeciesReference

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constant: true
value: 0.1
type: Parameter

meta e 0462
type: Species
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initial amount: NaN
is: P39002
initial concentration: 0.001
has only substance units: false
in compartment: meta cell
is: SBO:0000252
constant: true
is encoded by: sce:YIL009W
boundary condition: true
name: FAA3

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constant: true
value: 0.1
type: Parameter

meta e 0085
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is: P32473
type: Species
constant: true
boundary condition: true
is encoded by: sce:YBR221C
has only substance units: false
initial amount: NaN
in compartment: meta cell

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value: 0.00251625132250899
type: LocalParameter

meta e 0463
boundary condition: true
is encoded by: sce:YIL010W
type: Species
constant: true
initial amount: NaN
name: DOT5
initial concentration: 0.001
is: P40553
is: SBO:0000252
has only substance units: false
in compartment: meta cell
is encoded by: S000001272

meta s 1587
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type: Species
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has only substance units: false
is: SBO:0000247
initial concentration: 0.1
is version of: CHEBI:29186
initial amount: NaN
in compartment: meta cell
name: tRNA(Asp)

meta r 0510
type: Reaction
reversible: true
name: glycogen (starch) synthase
fast: false
is: SBO:0000176

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stoichiometry: 1.0
species: meta s 0739
type: SpeciesReference

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value: 0.00726411015276649
type: LocalParameter

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stoichiometry: 0.2862
species: meta s 1600
type: SpeciesReference

meta s 1364
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type: Species
initial concentration: 0.1
is: C04751
in compartment: meta cell
is: CHEBI:58564
constant: false
boundary condition: false
initial amount: NaN
is: SBO:0000247

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

meta s 1161
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name: myristate
type: Species
boundary condition: false
constant: false
initial amount: NaN
initial concentration: 0.1
in compartment: meta cell
is: CHEBI:30807
is: SBO:0000247

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constant: true
value: 0.1
type: Parameter

meta s 1589
constant: false
has only substance units: false
initial concentration: 0.1
is: C01639
type: Species
boundary condition: false
initial amount: NaN
in compartment: meta cell
is: CHEBI:29167
name: tRNA(Cys)
is: SBO:0000247

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0427
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 0.00625077817220527
type: LocalParameter

meta e 0352
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constant: true
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initial amount: NaN
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is: SBO:0000252
initial concentration: 0.001
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in compartment: meta cell
is: P07244

meta r 0512
is: R03654
reversible: true
name: glycyl-tRNA synthetase
is: SBO:0000176
fast: false
type: Reaction

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0573
type: SpeciesReference

meta e 0465
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is encoded by: S000001282
is encoded by: sce:YIL020C
initial concentration: 0.001
type: Species
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is: P40545
constant: true
boundary condition: true
in compartment: meta cell

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units: dimensionless
value: -1.0
type: LocalParameter

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value: 5.19949368301002E-4
type: LocalParameter

meta s 1011
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is: C01100
in compartment: meta cell
is: CHEBI:57980
constant: false
name: L-histidinol phosphate
initial amount: NaN
type: Species
is: SBO:0000247
initial concentration: 0.1
boundary condition: false

meta e 0088
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boundary condition: true
constant: true
is encoded by: sce:YBR249C
has only substance units: false
is: SBO:0000252
initial amount: NaN
type: Species
in compartment: meta cell
initial concentration: 0.001

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value: 0.0386660157978829
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0664
type: SpeciesReference

meta s 1010
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boundary condition: false
is: C00860
constant: false
initial concentration: 0.1
initial amount: NaN
type: Species
is: SBO:0000247
has only substance units: false
is: CHEBI:57699
name: L-histidinol

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0089
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name: DUT1
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is: P33317
is encoded by: sce:YBR252W
boundary condition: true
is: SBO:0000252
is encoded by: S000000456
initial amount: NaN
has only substance units: false
type: Species
constant: true

meta s 1583
type: Species
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initial amount: NaN
boundary condition: false
is: SBO:0000247
name: tRNA(Arg)
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in compartment: meta cell
initial concentration: 0.1
constant: false

meta e 0467
boundary condition: true
initial amount: NaN
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type: Species
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constant: true
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is encoded by: sce:YIL066C
is: SBO:0000252
in compartment: meta cell

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value: 0.10862767021555
type: LocalParameter

meta r 0269
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is: SBO:0000176
type: Reaction
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reversible: true

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1010
type: SpeciesReference

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exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
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meta e 0469
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is encoded by: S000001336

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units: dimensionless
value: -1.0
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stoichiometry: 1.0
species: meta s 1207
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meta e 0086
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constant: true
in compartment: meta cell
name: GPX2
is: SBO:0000252

meta s 1360
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initial amount: NaN
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constant: false
initial concentration: 0.1
is: SBO:0000247
is: CHEBI:58702
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meta s 1012
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boundary condition: false
constant: false
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initial amount: NaN
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is: SBO:0000247
type: Species
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stoichiometry: 0.0599
species: meta s 1545
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is: C00129
is: CHEBI:128769
is: SBO:0000247
constant: false
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initial amount: NaN
initial concentration: 0.1
in compartment: meta cell
name: isopentenyl diphosphate

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stoichiometry: 1.0
species: meta s 0965
type: SpeciesReference

meta r 0267
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is: SBO:0000176
reversible: true
fast: false
type: Reaction

meta r 1072
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reversible: true
is: SBO:0000176
is: R00158
name: UMP kinase
type: Reaction

meta s 1585
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initial concentration: 0.1
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is: SBO:0000247
in compartment: meta cell
initial amount: NaN
name: tRNA(Asn)
boundary condition: false

meta e 0087
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initial concentration: 0.001
is: P33734
boundary condition: true
name: HIS7
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is encoded by: sce:YBR248C
is: SBO:0000252
initial amount: NaN
type: Species
is encoded by: S000000452
constant: true

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value: 3.06632551696157E-5
type: LocalParameter

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value: 0.00155984810489089
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 4.33333333333333
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0434
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1207
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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units: dimensionless
value: -1.0
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meta e 0574
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is: SBO:0000252
boundary condition: true
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type: Species
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initial amount: NaN

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units: dimensionless
value: -1.0
type: LocalParameter

meta s 1604
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has only substance units: false
boundary condition: false
name: tRNA(Phe)
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initial amount: NaN
is: SBO:0000247
constant: false

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stoichiometry: 1.0
species: meta s 0633
type: SpeciesReference

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units: dimensionless
value: 1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 1538
type: SpeciesReference

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stoichiometry: 1.0
species: meta s 0999
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0006
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constant: true
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boundary condition: true
initial concentration: 0.001
initial amount: NaN
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is encoded by: sce:Q0250
name: COX2
is encoded by: S000007281
is: P00410
type: Species

meta e 0571
constant: true
type: Species
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is: P17505
initial amount: NaN
has only substance units: false
boundary condition: true
is encoded by: sce:YKL085W
is encoded by: S000001568
in compartment: meta cell
is: SBO:0000252
initial concentration: 0.001

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units: dimensionless
value: 1.0
type: LocalParameter

meta s 1607
initial amount: NaN
name: tRNA(Ser)
is: SBO:0000247
is: CHEBI:29179
is: C01650
constant: false
boundary condition: false
type: Species
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initial concentration: 0.1
has only substance units: false

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value: 1.02210853716592E-5
type: LocalParameter

meta e 0007
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is encoded by: sce:Q0275
boundary condition: true
initial amount: NaN
has only substance units: false
is encoded by: S000007283
is: SBO:0000252
name: COX3
type: Species
in compartment: meta cell

meta s 1337
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initial concentration: 0.1
type: Species
boundary condition: false
initial amount: NaN
constant: false
has only substance units: false
in compartment: meta cell
is: C02737
is: SBO:0000247
name: phosphatidyl-L-serine

meta s 1606
is: CHEBI:29177
in compartment: meta cell
initial concentration: 0.1
has only substance units: false
is: C01649
initial amount: NaN
boundary condition: false
is: SBO:0000247
name: tRNA(Pro)
constant: false
type: Species

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units: dimensionless
value: 1.0
type: LocalParameter

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value: 2.40277332169094E-4
type: LocalParameter

meta e 0008
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name: CYS3
boundary condition: true
initial amount: NaN
is: P31373
has only substance units: false
is encoded by: S000000010
is: SBO:0000252
constant: true
type: Species
in compartment: meta cell

http://identifiers.org/biomodels.db/BIOMD0000000471#b38b4fe5_f3e1_4add_ac7c_32b7138471bf
stoichiometry: 1.0
species: meta s 0394
type: SpeciesReference

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stoichiometry: 2.0
species: meta s 1212
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meta e 0004
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initial concentration: 0.001
name: COB
is: SBO:0000252
constant: true
initial amount: NaN
boundary condition: true
is: P00163
is encoded by: sce:Q0105
is encoded by: S000007270
in compartment: meta cell

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units: dimensionless
value: -1.0
type: LocalParameter

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stoichiometry: 1.0
species: meta s 0423
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000471#d05a7080_dc99_45c5_ab97_994a296355fc
name: fatty-acyl-CoA synthase (n-C12:0CoA)
type: Reaction
is: SBO:0000176
fast: false
reversible: true

meta s 0710
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constant: false
in compartment: meta cell
type: Species
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is: SBO:0000247
initial amount: NaN
initial concentration: 0.1
is: CHEBI:16928

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stoichiometry: 1.0
species: meta s 0999
type: SpeciesReference

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units: dimensionless
value: -1.0
type: LocalParameter

meta e 0578
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constant: true
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initial concentration: 0.001
is: P34163
initial amount: NaN
boundary condition: true
name: TGL1
is: SBO:0000252
type: Species
in compartment: meta cell

http://identifiers.org/biomodels.db/BIOMD0000000471#_2dd204fc_d8e3_41f6_bc04_54cbe65d3501
stoichiometry: 0.0036
species: meta s 0584
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units: dimensionless
value: -1.0
type: LocalParameter

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units: dimensionless
value: 1.0
type: LocalParameter

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constant: true
value: 0.1
type: Parameter

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units: dimensionless
value: 1.0
type: LocalParameter

meta e 0812
initial amount: NaN
boundary condition: true
is encoded by: S000005326
constant: true
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has only substance units: false
type: Species
is encoded by: sce:YNR043W
name: MVD1
is: SBO:0000252
is: P32377
initial concentration: 0.001

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stoichiometry: 1.0
species: meta s 1543
type: SpeciesReference

meta s 1600
initial concentration: 0.1
has only substance units: false
is: SBO:0000247
name: tRNA(Lys)
boundary condition: false
initial amount: NaN
constant: false
type: Species
in compartment: meta cell
is version of: CHEBI:29185

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constant: true
value: 0.1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000471#_79f9bc97_97a5_43d3_8426_5a03b10359c8
stoichiometry: 2.0
species: meta s 1207
type: SpeciesReference

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units: dimensionless
value: 1.1348
type: LocalParameter

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units: dimensionless
value: -1.0
type: LocalParameter