iron (III) transport via diffusion (extracellular to periplasm)
chloride (Cl-1) transport via diffusion (extracellular to periplasm)
2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate
4-amino-2-methyl-5-phosphomethylpyrimidine synthetase
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
3-phosphoshikimate 1-carboxyvinyltransferase
4,5-dihydroxy-2,3-pentanedione cyclization (spontaneous)
Phosphatidylserine decarboxylase (n-C16:0)
Phosphatidylserine decarboxylase (n-C16:1)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase
phosphatidylserine (dihexadec-9-enoyl, n-C16:1)
phosphatidylserine (dihexadecanoyl, n-C16:0)
cytochrome oxidase bd (ubiquinol-8: 2 protons) (periplasm)
cytochrome oxidase bd (menaquinol-8: 2 protons) (periplasm)
Sink needed to allow S-Adenosyl-4-methylthio-2-oxobutanoate to leave system
cyclic pyranopterin monophosphate synthase
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran synthesis (spontaneous)
phosphoadenylyl-sulfate reductase (thioredoxin)
nicotinate-nucleotide adenylyltransferase
iron (II) transport via diffusion (extracellular to periplasm)
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)
2-Octaprenylphenol hydroxylase (anaerobic)
2-Dehydro-3-deoxy-D-gluconate 6-phosphate
cobalt (Co+2) transport via diffusion (extracellular to periplasm)
3-Hydroxypimeloyl-[acyl-carrier protein] methyl ester
1-hexadec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:1)
1-hexadecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:0)
copper (Cu+2) transport via diffusion (extracellular to periplasm)
3-Oxotetradecanoyl-[acyl-carrier protein]
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (ipdp)
Fructose transport via PEP:Pyr PTS (f6p generating) (periplasm)
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (dmpp)
Erythronate 4-phosphate (4per) dehydrogenase
3-Hydroxyglutaryl-[acyl-carrier protein] methyl ester
cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)
UDP-3-O-(3-hydroxymyristoyl)glucosamine acyltransferase
Sink needed to allow (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran to leave system
Sink needed to allow 5'-deoxyribose to leave system
dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)
UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
glycine hydroxymethyltransferase, reversible
UDP-N-acetylenolpyruvoylglucosamine reductase
coproporphyrinogen oxidase (O2 required)
3,4-Dihydroxy-2-butanone-4-phosphate synthase
phospho-L-serine phosphatase (periplasmic)
phosphate transport via diffusion (extracellular to periplasm)
ammonia transport via diffusion (extracellular to periplasm)
phosphatidylethanolamine (dihexadecanoyl, n-C16:0)
1,2-dihexadec-9-enoyl-sn-glycerol 3-phosphate
1,2-dihexadecanoyl-sn-glycerol 3-phosphate
5-amino-6-(5-phosphoribosylamino)uracil reductase
phosphatidylethanolamine (dihexadec-9enoyl, n-C16:1)
nicotinate-nucleotide diphosphorylase (carboxylating)
5,10-methylenetetrahydrofolate reductase (NADH)
6-hydroxymethyl-dihydropterin pyrophosphokinase
D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate
Manganese (Mn+2) transport via diffusion (extracellular to periplasm)
ribonucleoside-triphosphate reductase (CTP) (flavodoxin)
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
UDP-N-acetylmuramoyl-L-alanine synthetase
glycerol-3-phosphate dehydrogenase (NADP)
[2Fe-1S] desulfurated iron-sulfur cluster
2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate
2-C-methyl-D-erythritol 2,4-cyclodiphosphate
nickel transport via diffusion (extracellular to periplasm)
dihydoorotic acid dehydrogenase (quinone8)
Sink needed to allow p-Cresol to leave system
glucosamine-1-phosphate N-acetyltransferase
two linked disacharide pentapeptide murein units (uncrosslinked, middle of chain)
3-Oxo-glutaryl-[acyl-carrier protein] methyl ester
O-Phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase
magnesium (Mg+2) transport via diffusion (extracellular to periplasm)
potassium transport via diffusion (extracellular to periplasm)
bis-molybdopterin mono-guanine dinucleotide
Dihydroneopterin triphosphate pyrophosphatase
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
glycerol-3-phosphate acyltransferase (C16:1)
glycerol-3-phosphate acyltransferase (C16:0)
nucleoside-diphosphate kinase (ATP:dTDP)
zinc (Zn+2) transport via diffusion (extracellular to periplasm)
3-deoxy-manno-octulosonate cytidylyltransferase
3-deoxy-D-manno-octulosonic acid transferase
Smallbone2013 - E.coli metabolic model with linlog rate law
3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
3-deoxy -D-manno-octulosonic -acid 8-phosphate synthase
acyl-[acyl-carrier-protein] synthetase (n-C16:0)
acyl-[acyl-carrier-protein] synthetase (n-C12:0)
pantetheine-phosphate adenylyltransferase
Methanol transport via diffusion (extracellular to periplasm)
D-glucose transport via PEP:Pyr PTS (periplasm)
Pimeloyl-[acyl-carrier protein] methyl ester
glutamate-1-semialdehyde aminotransferase
Enoylglutaryl-[ACP] methyl ester reductase
Enoylpimeloyl-[ACP] methyl ester reductase
ketol-acid reductoisomerase (2,3-dihydroxy-3-methylbutanoate)
ketol-acid reductoisomerase (2-Acetolactate)
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
(R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
Octaprenyl-hydroxybenzoate decarboxylase
aconitase (half-reaction B, Isocitrate hydro-lyase)
aconitase (half-reaction A, Citrate hydro-lyase)
ribonucleoside-triphosphate reductase (GTP) (flavodoxin)
3-hydroxyacyl-CoA dehydratase (3-hydroxyoctanoyl-CoA)
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexanoyl-CoA)
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexadecanoyl-CoA)
3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA)
sulfate transport via diffusion (extracellular to periplasm)
3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA)
3-hydroxyacyl-CoA dehydratase (3-hydroxytetradecanoyl-CoA)
murein crosslinking transpeptidase 1A:(A2pm->D-ala) (periplasm)
2,3,2'3'-Tetrakis(beta-hydroxymyristoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
acetyl-CoA C-acyltransferase (tetradecanoyl-CoA) (r)
acetyl-CoA C-acyltransferase (octanoyl-CoA) (r)
acetyl-CoA C-acyltransferase (hexanoyl-CoA) (r)
2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate
acetyl-CoA C-acyltransferase (dodecanoyl-CoA) (r)
acetyl-CoA C-acyltransferase (decanoyl-CoA) (r)
Dihydroneopterin monophosphate dephosphorylase
acetyl-CoA C-acyltransferase (butanoyl-CoA) (r)
fatty-acid-CoA thioesterase (hexadecanoate)
2C-methyl-D-erythritol 2,4 cyclodiphosphate dehydratase
3-hydroxyacyl-CoA dehydratase (3-hydroxydecanoyl-CoA)
3-hydroxyacyl-CoA dehydratase (3-hydroxydodecanoyl-CoA)
glyceraldehyde-3-phosphate dehydrogenase
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA)
acetaldehyde dehydrogenase (acetylating)
molybdate transport via diffusion (extracellular to periplasm)
ribonucleoside-triphosphate reductase (UTP) (flavodoxin)
3-dehydroquinate dehydratase, irreversible
methylenetetrahydrofolate dehydrogenase (NADP)
glutamine-fructose-6-phosphate transaminase
Enoylglutaryl-[acyl-carrier protein] methyl ester
2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5'-phosphate
tryptophan synthase (indoleglycerol phosphate)
3-Oxo-pimeloyl-[acyl-carrier protein] methyl ester
glutamine phosphoribosyldiphosphate amidotransferase
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
fatty-acid-CoA thioesterase (dodecanoate)
3-Oxo-pimeloyl-[ACP] methyl ester reductase
3-Oxo-glutaryl-[ACP] methyl ester synthase
3-Oxo-pimeloyl-[ACP] methyl ester dehydratase
3-Oxo-glutaryl-[ACP] methyl ester reductase
3-Oxo-glutaryl-[ACP] methyl ester dehydratase
3-methyl-2-oxobutanoate hydroxymethyltransferase
6-hydroxymethyl-dihydropterin pyrophosphate
ribonucleoside-triphosphate reductase (ATP) (flavodoxin)
adenosylmethionine-8-amino-7-oxononanoate transaminase
3-Deoxy-D-manno-octulosonate 8-phosphate
Dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)
oxygen transport via diffusion (extracellular to periplasm)
purine-nucleoside phosphorylase (Adenosine)
ATP synthase (four protons for one ATP) (periplasm)
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)
3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA)
3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA)
3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA)
pyridoxine 5'-phosphate oxidase (anaerboic
3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA)
CO2 transport via diffusion (extracellular to periplasm)
D-glucose transport via diffusion (extracellular to periplasm) irreversible
2-Oxo-4-methyl-3-carboxypentanoate decarboxylation
uroporphyrinogen decarboxylase (uroporphyrinogen III)
Glutaryl-[acyl-carrier protein] methyl ester
bis-molybdopterin guanine dinucleotide synthase
Enoylpimeloyl-[acyl-carrier protein] methyl ester
bis-molybdopterin guanine dinucleotide synthase (single GDP)
3-oxoacyl-[acyl-carrier-protein] synthase (n-C14:0)
phosphoribosylaminoimidazolecarboxamide formyltransferase
two disacharide linked murein units, pentapeptide crosslinked tetrapeptide (A2pm->D-ala) (middle of chain)
phosphoribosylaminoimidazole carboxylase
phosphoribosylaminoimidazole carboxylase (mutase rxn)
phosphopantothenoylcysteine decarboxylase
acyl-CoA dehydrogenase (tetradecanoyl-CoA)
diaminohydroxyphosphoribosylaminopryrimidine deaminase (25drapp)
phosphoribosylanthranilate isomerase (irreversible)
phosphoribosylaminoimidazolesuccinocarboxamide synthase
calcium (Ca+2) transport via diffusion (extracellular to periplasm)
L-glutamate 5-semialdehyde dehydratase (spontaneous)
acyl-CoA dehydrogenase (hexadecanoyl-CoA)
Nicotinamide adenine dinucleotide - reduced
Nicotinamide adenine dinucleotide phosphate
Nicotinamide adenine dinucleotide phosphate - reduced
3-oxoacyl-[acyl-carrier-protein] reductase (n-C14:0)
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
2-dehydro-3-deoxy-phosphogluconate aldolase
1-hexadec-9-enoyl-sn-glycerol 3-phosphate
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
fatty-acid-CoA thioesterase (hexadecenoate)
acyl-[acyl-carrier-protein] synthetase (n-C16:1)
phosphoribosylformylglycinamidine synthase
3-Oxo-pimeloyl-[ACP] methyl ester synthase