COPASI130
fast: false
reversible: false
name: Degradation of M1-vRNP complexes in the nucleus
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_67fcffb9_7b98_4d7c_8b8c_ae253765a9f9
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_2e240223_34ba_44b8_8296_c8b4b6402fd4
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

COPASI120
fast: false
reversible: false
name: Synthesis of HA
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_8cb14922_47f9_449b_92ee_d2141ba98536
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#b3d0bddd_bfb9_4389_9972_4d3f40b45962
value: 1650.0
name: KmH
type: LocalParameter

COPASI110
fast: false
reversible: false
name: Synthesis of mRNA of segment 6
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_070e2b3f_d927_422b_9ec5_4f8d14127b49
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#f56b6610_70cf_4c90_8705_d2bea9fe9f80
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_6ec50ed4_b99e_441f_ac49_024cd2ce4687
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_718b9e9e_eff0_4103_b53b_4cca4ec9aa34
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_087e2a04_9c7f_42fc_84ed_e08ffb9b1078
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#f31a7a89_ea17_4246_98eb_7b8d1565b736
stoichiometry: 1.0
species: COPASI31
type: SpeciesReference

COPASI122
fast: false
reversible: false
name: Synthesis of M2
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#ab5eb159_b182_495f_ad60_5e460ea774e8
value: 450.0
name: KmB
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_867d9342_4518_41d7_a6e9_2908ffda6457
stoichiometry: 1.0
species: COPASI35
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_216f301d_ace5_401b_9c3e_f4f86e2ec721
stoichiometry: 71.0
species: COPASI15
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#e674ccb9_3377_41d9_87cf_69b1f92c665c
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_56c6ea51_ed5f_4b3f_82f7_76b286d617db
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_1dbc9d4b_a2d4_4593_be7d_1da2b5a0dc64
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

COPASI70
notes: synthesis rate of NEP proteins (1/h)
constant: false
value: 50.625
name: kSynP_NEP
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_9ade80cc_4a8c_48c3_87a5_d21cefd421dd
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#edb36ccf_a0de_469e_b0ee_afc762b36291
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

W3 CDTF: Wed Oct 09 13:58:00 BST 2013

http://identifiers.org/biomodels.db/BIOMD0000000463#b256dcaf_11ff_41ae_855d_f8d4768145d3
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

COPASI121
fast: false
reversible: false
name: Synthesis of NA
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#f248bef8_0868_41db_83d3_5ca8ec01bc02
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#bc1608b3_cac7_46f4_8c69_21186e3da342
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#a1fce1c1_3f0e_469f_9a43_83fa535ca707
name: volume
type: SBMLUnitsDef

COPASI134
fast: false
reversible: false
name: Degradation of mRNA of segment 3
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#bd750410_45fe_42f3_bfa0_92a089ab340b
stoichiometry: 37.0
species: COPASI13
type: SpeciesReference

COPASI3
boundary condition: false
initial concentration: 150.0
name: Bhi
in compartment: COPASI2
initial amount: NaN
notes: free high-affinity binding sites (sites)
type: Species
constant: false
has only substance units: false
substance units: mole

http://identifiers.org/biomodels.db/BIOMD0000000463#d1afd016_2335_46d2_ae24_5843f095bbf8
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_4d214602_5fc0_4300_b278_2687ae839ec0
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#d9abefac_863c_4ce5_b52e_c62e9e6364ef
stoichiometry: 1.0
species: COPASI31
type: SpeciesReference

COPASI133
fast: false
reversible: false
name: Degradation of mRNA of segment 2
type: Reaction

COPASI2
is: GO:0005623
constant: true
units: litre
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

http://identifiers.org/biomodels.db/BIOMD0000000463#_8c7bd3ed_6349_4030_ae2b_990cba37c6e7
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#d62053c6_cd14_4cac_bcc6_5776fce9d1a4
stoichiometry: 1.0
species: COPASI30
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#db3c3ee6_e3b8_4720_b607_ffb0f22e90fe
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#f2a2e084_f5ef_4e3c_aeb4_903a8116eced
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_840cfe22_585f_497c_b34f_76e350aed554
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#d098c7e4_bec8_41e9_86e6_9017a304b1f9
value: 5000.0
name: KmC
type: LocalParameter

COPASI132
fast: false
reversible: false
name: Degradation of mRNA of segment 1
type: Reaction

COPASI5
substance units: mole
initial amount: NaN
name: Vex
boundary condition: false
in compartment: COPASI2
constant: false
type: Species
notes: virions in the extracellular medium (virions)
initial concentration: 10.0
has only substance units: false

COPASI131
fast: false
reversible: false
name: Degradation of M1-vRNP complexes in the cytoplasm
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#a697f578_c32d_43d4_a45f_c27a88f3d5d9
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

COPASI4
notes: virions attached to high-affinity binding sites (virions)
boundary condition: false
constant: false
type: Species
name: VattHi
has only substance units: false
initial concentration: 0.0
substance units: mole
in compartment: COPASI2
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000463#_8cf7abef_3107_404c_ac3e_76828ce641bb
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

COPASI118
fast: false
reversible: false
name: Synthesis of M1
type: Reaction

COPASI106
fast: false
reversible: false
name: Synthesis of mRNA of segment 2
type: Reaction

COPASI16
in compartment: COPASI2
name: P_M1
type: Species
boundary condition: false
substance units: mole
initial amount: NaN
constant: false
has only substance units: false
initial concentration: 0.0
notes: M1 proteins (molecules)

COPASI128
fast: false
reversible: false
name: Degradation of RdRp-vRNA
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#a7df2a82_4c50_4f75_be43_8fcc6a266fbd
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_99fae9cc_5454_4862_9e35_c7d8302ac63f
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

COPASI138
fast: false
reversible: false
name: Degradation of mRNA of segment 7
type: Reaction

COPASI105
fast: false
reversible: false
name: Synthesis of mRNA of segment 1
type: Reaction

COPASI117
fast: false
reversible: false
name: Synthesis of NP
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_122b3ec4_640d_4d0b_a48b_3f5b377b35b6
stoichiometry: 1.0
species: COPASI26
type: SpeciesReference

COPASI15
name: P_Np
substance units: mole
type: Species
has only substance units: false
initial amount: NaN
constant: false
boundary condition: false
in compartment: COPASI2
initial concentration: 0.0
notes: NP proteins (molecules)

COPASI127
fast: false
reversible: false
name: Degradation of RdRp-cRNA
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#edfae76b_3ea2_4447_9a79_c96d75b37668
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI29
constant: false
in compartment: COPASI2
substance units: mole
boundary condition: false
has only substance units: false
name: Rm8
initial concentration: 0.0
notes: unspliced mRNA of segment 8 (molecules)
initial amount: NaN
type: Species

COPASI137
fast: false
reversible: false
name: Degradation of mRNA of segment 6
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_48356cc2_bb0d_421f_b916_d7dfde18d0ba
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#c9b351d1_a18d_42e8_9312_8e8a6547cefd
stoichiometry: 2932.0
species: COPASI16
type: SpeciesReference

COPASI116
reversible: false
name: Formation of polymerases
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000463#_93141527_b2a8_4e0f_9d99_8a1298b14c36
exponent: 1.0
scale: 0
multipler: 1.0
kind: DIMENSIONLESS
type: SBMLUnit

http://identifiers.org/biomodels.db/BIOMD0000000463#_6ceb59c1_7197_4ff0_a7da_140d121a80b7
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

COPASI104
type: Reaction
reversible: false
fast: false
name: Binding of NP to RdRp-vRNA complexes

COPASI39
initial amount: NaN
type: Species
name: total cRNA of a segment
substance units: mole
initial concentration: 0.0
has only substance units: false
in compartment: COPASI2
boundary condition: true
notes: total amount of cRNA in the cell considering an arbitrary segment (molecules)
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000463#_371e0025_dee1_44ed_a218_ebe00c1fb895
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#d8ad686b_eb24_4497_b5d9_c9bac739ad90
name: length
type: SBMLUnitsDef

COPASI28
type: Species
name: Rm7
substance units: mole
boundary condition: false
notes: unspliced mRNA of segment 7 (molecules)
initial amount: NaN
initial concentration: 0.0
constant: false
has only substance units: false
in compartment: COPASI2

http://identifiers.org/biomodels.db/BIOMD0000000463#e21db5be_0957_41a0_b000_a172e386a619
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#c3cbc01f_65d5_4baf_9235_0bd2a62b6502
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#d4f53069_00ef_4e9a_a364_69e8fe18676e
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

COPASI90
reversible: true
name: Binding of virions to high-affinity sites
fast: false
type: Reaction

BIOMD0000000463
parameter: COPASI63
species: COPASI20
reaction: COPASI118
parameter: COPASI46
parameter: COPASI75
reaction: COPASI100
reaction: COPASI92
curated: true
reaction: COPASI114
reaction: COPASI111
reaction: COPASI107
reaction: COPASI99
species: COPASI35
parameter: COPASI71
parameter: COPASI89
reaction: COPASI123
parameter: COPASI51
species: COPASI9
species: COPASI23
reaction: COPASI108
parameter: COPASI72
reaction: COPASI101
species: COPASI34
reaction: COPASI93
parameter: COPASI86
species: COPASI11
reaction: COPASI119
parameter: COPASI52
species: COPASI22
reaction: COPASI94
parameter: COPASI61
species: COPASI10
parameter: COPASI81
reaction: COPASI109
species: COPASI37
compartment: COPASI2
parameter: COPASI73
reaction: COPASI90
reaction: COPASI131
parameter: COPASI53
species: COPASI25
parameter: COPASI74
species: COPASI36
species: COPASI13
reaction: COPASI103
reaction: COPASI98
parameter: COPASI88
type: SBMLModel
species: COPASI24
reaction: COPASI139
parameter: COPASI67
function def: COPASI141
parameter: COPASI50
parameter: COPASI47
species: COPASI12
parameter: COPASI79
reaction: COPASI135
reaction: COPASI104
parameter: COPASI64
parameter: COPASI59
reaction: COPASI133
reaction: COPASI115
parameter: COPASI43
reaction: COPASI120
species: COPASI29
species: COPASI27
parameter: COPASI60
species: COPASI39
is version of: GO:0046718
reaction: COPASI127
parameter: COPASI55
parameter: COPASI80
reaction: COPASI112
species: COPASI38
species: COPASI15
parameter: COPASI76
reaction: COPASI105
species: COPASI26
parameter: COPASI69
reaction: COPASI128

COPASI136
fast: false
reversible: false
name: Degradation of mRNA of segment 5
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#d5150009_49fa_423d_8396_983798e3d717
stoichiometry: 1.0
species: COPASI36
type: SpeciesReference

COPASI18
initial concentration: 0.0
in compartment: COPASI2
has only substance units: false
substance units: mole
notes: M1-vRNP complexes in the cytoplasm (virions)
initial amount: NaN
type: Species
boundary condition: false
constant: false
name: VpCytM1

COPASI17
notes: M1-vRNP complexes in the nucleus (virions)
substance units: mole
type: Species
initial amount: NaN
constant: false
has only substance units: false
boundary condition: false
in compartment: COPASI2
initial concentration: 0.0
name: VpNucM1

COPASI115
fast: false
reversible: false
name: Synthesis of PA
type: Reaction

COPASI103
reversible: false
fast: false
name: Binding of polymerase to nascent vRNA
type: Reaction

COPASI129
fast: false
reversible: false
name: Degradation of cRNPs
type: Reaction

COPASI27
constant: false
has only substance units: false
in compartment: COPASI2
boundary condition: false
name: Rm6
initial concentration: 0.0
notes: mRNA of segment 6 (molecules)
type: Species
substance units: mole
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000463#_4b5af3f0_9cfe_4a23_adca_e0cb619430a3
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

COPASI135
fast: false
reversible: false
name: Degradation of mRNA of segment 4
type: Reaction

COPASI124
fast: false
reversible: false
name: Degradation of vRNPs in the nucleus
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_48cc2971_fd9e_4828_a528_1f2ea3c1058d
stoichiometry: 8.5
species: COPASI16
type: SpeciesReference

COPASI102
fast: false
reversible: false
name: Synthesis of vRNA
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#e4d1070d_69f8_4bc0_8322_b1166f31dcf2
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI114
fast: false
reversible: false
name: Synthesis of PB2
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_08bdd6a4_482f_4aad_8f05_6010cccf0c87
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

COPASI92
fast: false
reversible: false
name: Endocytosis of virions bound to high-affinity sites
type: Reaction

COPASI82
notes: synthesis rate of segment 3's mRNA (1/h)
constant: false
value: 14.1338760741746
name: kSynM3
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_17862aa6_0c9e_4f6e_acf7_437d890c60a3
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#dd4b3bbd_7450_4f38_b768_e133f629b9f7
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_0b25452d_9e96_4e21_bb7d_d04cee4b593b
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#f67e6f1f_d651_459c_bf7c_e973c5110921
stoichiometry: 433.0
species: COPASI15
type: SpeciesReference

COPASI101
name: Nuclear export of vRNPs
reversible: false
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000463#d3aaa3ac_86b9_4e99_8e75_3d4cefd0799a
stoichiometry: 71.0
species: COPASI15
type: SpeciesReference

COPASI123
name: Virus release
fast: false
type: Reaction
reversible: false

COPASI113
fast: false
reversible: false
name: Synthesis of PB1
type: Reaction

COPASI19
notes: cRNPs (molecules)
has only substance units: false
boundary condition: false
in compartment: COPASI2
initial amount: NaN
substance units: mole
type: Species
initial concentration: 0.0
constant: false
name: Cp

COPASI91
type: Reaction
name: Binding of virions to low-affinity sites
fast: false
reversible: true

COPASI81
notes: synthesis rate of segment 2's mRNA (1/h)
constant: false
value: 13.4698275862069
name: kSynM2
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_00f74539_f9c9_4a8d_a9eb_a9bf59a40b6c
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

COPASI100
type: Reaction
reversible: false
name: Binding of M1 to vRNPs in the nucleus
fast: false

COPASI126
fast: false
reversible: false
name: Degradation of nascent vRNA
type: Reaction

COPASI112
fast: false
reversible: false
name: Synthesis of mRNA of segment 8
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#ce4c5264_adee_4c1f_85b1_8da93097ef57
exponent: 2.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

http://identifiers.org/biomodels.db/BIOMD0000000463#_1a6ce4d3_51f7_49eb_ad7c_3fa9a64479d2
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_65011a13_49ee_4b07_8743_ca9fd47697e4
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_295d620a_facf_427e_8b49_686f2daa551a
stoichiometry: 1.0
species: COPASI34
type: SpeciesReference

COPASI94
fast: false
reversible: false
name: Fusion of virions with endosomes
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_02c30e57_a85c_457f_a414_9f660688c5ee
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

COPASI80
notes: synthesis rate of segment 1's mRNA (1/h)
constant: false
value: 13.4698275862069
name: kSynM1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#b57ebd43_423b_43ba_b496_83bb48d13089
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#d0945f65_c724_4a06_888e_9d2c7765beed
name: time
type: SBMLUnitsDef

COPASI111
fast: false
reversible: false
name: Synthesis of mRNA of segment 7
type: Reaction

COPASI125
fast: false
reversible: false
name: Degradation of nascent cRNA
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_0c436316_7ddd_4945_83d3_485aac7ac339
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_8e82d718_361f_4b4f_9358_ca0b7291a120
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

COPASI93
fast: false
reversible: false
name: Endocytosis of virions bound to low-affinity sites
type: Reaction

COPASI139
fast: false
reversible: false
name: Degradation of mRNA of segment 8
type: Reaction

ORG:
  orgname: Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany
n:
  given: Frank Stefan
  family: Heldt

COPASI85
notes: synthesis rate of segment 6's mRNA (1/h)
constant: false
value: 22.4497126436782
name: kSynM6
type: Parameter

COPASI13
initial amount: NaN
in compartment: COPASI2
constant: false
initial concentration: 0.0
type: Species
substance units: mole
boundary condition: false
has only substance units: false
notes: viral polymerase complex (molecules)
name: P_Rdrp

http://identifiers.org/biomodels.db/BIOMD0000000463#dac4dc82_dbe9_449d_b15a_68a23f141903
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

COPASI95
fast: false
reversible: false
name: Degradation of virions in endosomes
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#f4d566f5_f782_41ee_b5ed_ad4fc4feb4fb
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

COPASI56
notes: combined rate of NEP binding to M1-vRNP complexes and subsequent transport out of the nucleus (1/(molecule*h))
constant: true
value: 1.0E-6
name: kExp
type: Parameter

COPASI33
in compartment: COPASI2
type: Species
boundary condition: false
constant: false
name: P_Nep
initial concentration: 0.0
notes: NEP proteins (molecules)
substance units: mole
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000463#_80fe83de_db94_4593_b527_b6ebf6651892
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

COPASI46
notes: endocytosis rate of virions bound to high-affinity or low-affinity binding sites (1/h)
constant: true
value: 4.8
name: kEn
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#c7b749ae_9315_4877_8a8b_784fec985e93
stoichiometry: 1.0
species: COPASI32
type: SpeciesReference

COPASI86
notes: synthesis rate of segment 7's mRNA (1/h)
constant: false
value: 31.0945273631841
name: kSynM7
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_48b25c02_2225_46c0_b88e_c4119a780373
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI14
initial concentration: 0.0
initial amount: NaN
notes: complex of viral polymerase and cRNA (molecules)
in compartment: COPASI2
has only substance units: false
constant: false
name: RcRdrp
substance units: mole
type: Species
boundary condition: false

COPASI96
fast: false
reversible: false
name: Nuclear import of vRNPs
type: Reaction

COPASI55
notes: binding rate of M1 to nuclear vRNPs (1/(h*molecule))
constant: true
value: 1.39E-6
name: kBindM1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_89db7f0b_51bc_4e96_947e_cb6af8c0b502
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

COPASI20
has only substance units: false
initial concentration: 0.0
name: Rv
boundary condition: false
notes: nascent vRNA (molecules)
substance units: mole
type: Species
in compartment: COPASI2
constant: false
initial amount: NaN

COPASI34
initial amount: NaN
substance units: mole
has only substance units: false
type: Species
notes: HA proteins (molecules)
in compartment: COPASI2
boundary condition: false
initial concentration: 0.0
constant: false
name: P_Ha

http://identifiers.org/biomodels.db/BIOMD0000000463#b60d9415_1723_4313_b9c6_2d831d273907
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

COPASI45
notes: dissociation rate of virions from low-affinity binding sites (1/h)
constant: false
value: 5.46218487394958
name: kDisLo
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_6ae8b8e0_ed29_4ff4_9ea1_5ef4e19d821c
stoichiometry: 8.0
species: COPASI10
type: SpeciesReference

COPASI83
notes: synthesis rate of segment 4's mRNA (1/h)
constant: false
value: 17.7859988616961
name: kSynM4
type: Parameter

COPASI11
in compartment: COPASI2
initial concentration: 0.0
initial amount: NaN
constant: false
has only substance units: false
type: Species
substance units: mole
boundary condition: false
notes: vRNPs in the nucleus (virions)
name: VpNuc

http://identifiers.org/biomodels.db/BIOMD0000000463#cb218ee6_f025_48c8_be4f_480ae10bd4cb
stoichiometry: 500.0
species: COPASI34
type: SpeciesReference

COPASI97
fast: false
reversible: false
name: Synthesis of cRNA
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#c2704aad_de39_4fcc_9a27_51841886b61c
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_6e048dcb_e0e8_4c0a_8333_ecbc9f1e24a8
stoichiometry: 1.0
species: COPASI33
type: SpeciesReference

COPASI21
substance units: mole
in compartment: COPASI2
type: Species
name: RvRdrp
notes: complex of viral polymerase and vRNA (molecules)
boundary condition: false
constant: false
initial concentration: 0.0
initial amount: NaN
has only substance units: false

COPASI58
notes: formation rate of functional polymerase complexes from the three subunits (1/(h*molecule^2))
constant: true
value: 1.0
name: kRdrp
type: Parameter

COPASI31
in compartment: COPASI2
boundary condition: false
constant: false
initial amount: NaN
name: P_Pb2
has only substance units: false
notes: PB2 proteins (molecules)
initial concentration: 0.0
substance units: mole
type: Species

COPASI44
notes: dissociation rate of virions from high-affinity binding sites (1/h)
constant: false
value: 7.15929203539823
name: kDisHi
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#d94316ae_aa07_4410_88c1_979f15504af2
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_528fa0ee_62ba_43ad_a28c_90d5571ecbe7
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

COPASI12
notes: nascent cRNA (molecules)
initial concentration: 0.0
name: Rc
in compartment: COPASI2
initial amount: NaN
boundary condition: false
constant: false
type: Species
has only substance units: false
substance units: mole

http://identifiers.org/biomodels.db/BIOMD0000000463#e6594513_61a4_46d1_ba31_4d8430b03a98
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI98
reversible: false
name: Binding of polymerase to nascent cRNA
fast: false
type: Reaction

COPASI84
notes: synthesis rate of segment 5's mRNA (1/h)
constant: false
value: 20.2922077922078
name: kSynM5
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_73535c2f_f639_490a_baa0_4160a90d6f23
stoichiometry: 100.0
species: COPASI35
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#ec0c83d3_80f3_4f3f_bb54_95732c3d7ed9
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

COPASI22
in compartment: COPASI2
type: Species
initial concentration: 0.0
notes: mRNA of segment 1 (molecules)
constant: false
name: Rm1
initial amount: NaN
has only substance units: false
substance units: mole
boundary condition: false

COPASI57
notes: fraction of protein synthesis rate and distance between two adjacent ribosomes (1/h)
constant: false
value: 405.0
name: kSynP_Drib
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#f4a1590a_c53c_4dd9_bfa0_09f5be260d7c
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

COPASI43
notes: attachment rate of virus particles to low-affinity binding sites (1/(site*h))
constant: true
value: 4.55E-4
name: kAttLo
type: Parameter

COPASI32
has only substance units: false
substance units: mole
initial amount: NaN
notes: PA proteins (molecules)
type: Species
boundary condition: false
in compartment: COPASI2
initial concentration: 0.0
name: P_Pa
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000463#_0e7d9bb6_5399_42ad_8338_05531e3d370d
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI89
notes: equilibrium constant for the attachment of virions to the low-affinity binding sites (1/site)
constant: true
value: 8.33E-5
name: kEqLo
type: Parameter

COPASI99
name: Binding of NP to RdRp-cRNA complexes
reversible: false
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000463#d47ead10_d875_489a_95a3_07b391a34a89
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

COPASI37
initial concentration: 0.0
substance units: mole
notes: total amount of released virions (virions)
type: Species
in compartment: COPASI2
boundary condition: false
initial amount: NaN
constant: false
name: Vrel
has only substance units: false

COPASI109
fast: false
reversible: false
name: Synthesis of mRNA of segment 5
type: Reaction

COPASI23
has only substance units: false
initial concentration: 0.0
type: Species
notes: mRNA of segment 2 (molecules)
substance units: mole
constant: false
in compartment: COPASI2
initial amount: NaN
boundary condition: false
name: Rm2

COPASI79
notes: synthesis rate of mRNAs (nucleotides/h)
constant: true
value: 250000.0
name: kSynM
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#b056e068_ee40_410f_be46_926a7a30e567
exponent: 1.0
scale: 0
multipler: 1.0
kind: DIMENSIONLESS
type: SBMLUnit

COPASI69
notes: synthesis rate of M2 proteins (1/h)
constant: false
value: 8.1
name: kSynP_M2
type: Parameter

COPASI10
in compartment: COPASI2
boundary condition: false
name: VpCyt
substance units: mole
initial amount: NaN
has only substance units: false
constant: false
notes: parental vRNPs in the cytoplasm (virions)
initial concentration: 0.0
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000463#_9a551ce0_854a_4824_8f59_69ad647e09cf
value: 1000.0
name: KmE
type: LocalParameter

COPASI49
notes: nuclear import rate of cytoplasmic vRNPs which are not bound to M1 (1/h)
constant: true
value: 6.0
name: kImp
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#a3c510f0_1b80_4e4c_ad96_9ff3ba9b66a7
name: area
type: SBMLUnitsDef

COPASI38
notes: total amount of cRNA in the cell considering all segments (molecules)
has only substance units: false
type: Species
name: total cRNA
substance units: mole
initial amount: NaN
boundary condition: true
in compartment: COPASI2
constant: false
initial concentration: 0.0

http://identifiers.org/biomodels.db/BIOMD0000000463#_13ed1689_f67e_48bd_9d25_da1fb02a5474
name: substance
type: SBMLUnitsDef

COPASI24
name: Rm3
substance units: mole
notes: mRNA of segment 3 (molecules)
boundary condition: false
constant: false
in compartment: COPASI2
initial concentration: 0.0
initial amount: NaN
has only substance units: false
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000463#_46a2bd98_984e_41d1_b954_0c3c4e9c0245
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

COPASI59
notes: release rate of progeny virions from the cell (virions/(molecule*h))
constant: true
value: 0.0037
name: kRel
type: Parameter

COPASI87
notes: synthesis rate of segment 8's mRNA (1/h)
constant: false
value: 36.0023041474654
name: kSynM8
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_67e46c66_129d_4f65_b885_17265686648b
stoichiometry: 1.0
species: COPASI32
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_4d5b619d_9175_41c5_9292_f1996fa133d7
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

COPASI68
notes: synthesis rate of M1 proteins (1/h)
constant: false
value: 396.9
name: kSynP_M1
type: Parameter

COPASI48
notes: degradation rate of virions which do not fuse with the endosomal membrane (1/h)
constant: false
value: 3.08411764705882
name: kDegVen
type: Parameter

COPASI35
initial concentration: 0.0
type: Species
name: P_Na
has only substance units: false
substance units: mole
in compartment: COPASI2
constant: false
notes: NA proteins (molecules)
initial amount: NaN
boundary condition: false

COPASI119
fast: false
reversible: false
name: Synthesis of NEP
type: Reaction

COPASI25
initial concentration: 0.0
substance units: mole
notes: mRNA of segment 4 (molecules)
boundary condition: false
type: Species
initial amount: NaN
in compartment: COPASI2
constant: false
name: Rm4
has only substance units: false

COPASI107
fast: false
reversible: false
name: Synthesis of mRNA of segment 3
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000463#_0672b324_88ee_438c_95c3_3ef6c72869f7
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

COPASI88
notes: equilibrium constant for the attachment of virions to the high-affinity binding sites (1/site)
constant: true
value: 0.0113
name: kEqHi
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_8b777d64_6755_4144_8a8b_f35234f3c402
stoichiometry: 1.0
species: COPASI33
type: SpeciesReference

COPASI67
notes: fraction of spliced NEP mRNAs compared to total mRNAs of segment 8 (-)
constant: true
value: 0.125
name: Fspl8
type: Parameter

COPASI36
constant: false
has only substance units: false
boundary condition: false
notes: M2 proteins (molecules)
type: Species
substance units: mole
in compartment: COPASI2
initial concentration: 0.0
name: P_M2
initial amount: NaN

COPASI47
notes: fusion rate of virions in late endosomes (1/h)
constant: true
value: 3.21
name: kFus
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#c24c78a4_5a5d_460d_907b_550211b7149f
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI108
fast: false
reversible: false
name: Synthesis of mRNA of segment 4
type: Reaction

COPASI26
substance units: mole
type: Species
initial amount: NaN
in compartment: COPASI2
constant: false
initial concentration: 0.0
has only substance units: false
notes: mRNA of segment 5 (molecules)
boundary condition: false
name: Rm5

http://identifiers.org/biomodels.db/BIOMD0000000463#_2ca17506_50e0_4c9f_9b05_db4370437e6f
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#dadf7d8c_5e1b_4cba_98af_16afd88f1bee
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_1a3315a2_07dc_484b_aadf_26e981525fe1
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

COPASI6
boundary condition: false
notes: free low-affinity binding sites (sites)
initial concentration: 1000.0
initial amount: NaN
type: Species
constant: false
in compartment: COPASI2
has only substance units: false
name: Blo
substance units: mole

http://identifiers.org/biomodels.db/BIOMD0000000463#_15fd9908_0bf6_4b73_a8d7_ad559666faba
value: 400.0
name: KmG
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_97a190ca_0fe1_4a6a_8e5a_67e5889a01a5
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_22988e76_a0b5_4932_8ba6_7f98032dc3a9
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#f485bffd_4fbe_4a53_8e14_6b476ff11032
stoichiometry: 1.0
species: COPASI26
type: SpeciesReference

COPASI66
notes: fraction of spliced M2 mRNAs compared to total mRNAs of segment 7 (-)
constant: true
value: 0.02
name: Fspl7
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_94d6a7a3_dfdd_4dc8_8b7e_979b157f05df
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI76
notes: length of segment 6's mRNA encoding NA (nucleotides)
constant: true
value: 1392.0
name: L6
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#c3b67813_e19f_41ee_a52a_a805625e21c8
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#e249fd01_7c72_48bd_ad11_52af909c5e76
stoichiometry: 1.0
species: COPASI26
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_0128f736_ae93_49c1_9194_6eec74666af4
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI7
notes: virions attached to low-affinity binding sites (virions)
in compartment: COPASI2
constant: false
type: Species
name: VattLo
substance units: mole
initial amount: NaN
boundary condition: false
has only substance units: false
initial concentration: 0.0

http://identifiers.org/biomodels.db/BIOMD0000000463#b16e48c8_91f4_4175_8374_c594f5f109c0
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

COPASI65
notes: distance between two adjacent ribosomes on an mRNA (nucleotides)
constant: true
value: 160.0
name: Drib
type: Parameter

COPASI75
notes: length of segment 5's mRNA encoding NP (nucleotides)
constant: true
value: 1540.0
name: L5
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#da1818a5_c9dd_43f4_9efb_ba75c8454f5f
stoichiometry: 157.0
species: COPASI33
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#b9fea7a2_f926_428e_9024_f6ca16ec8d7b
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_162d2bad_44ce_4264_94b1_e2ebefac555b
value: 30000.0
name: KmF
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000463#be5e7890_6e22_454e_bf30_0395d1c28eee
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_83d26ff9_adbf_476f_ab97_276f2a91e4e9
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#b68fd87d_1a10_4775_a705_c84de91557ca
value: 10000.0
name: KmD
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_6c28e92c_dfff_4afa_9965_8e97f3ab161d
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

COPASI8
substance units: mole
type: Species
initial amount: NaN
name: Ven
notes: virions in endosomes (virions)
has only substance units: false
boundary condition: false
in compartment: COPASI2
initial concentration: 0.0
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000463#d2d5c455_cc27_40cc_ae70_8a6d16f2cae4
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

COPASI50
notes: synthesis rate of proteins (nucleotides/h)
constant: true
value: 64800.0
name: kSynP
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#c9852d88_d413_4d71_b977_083db9eaf2b4
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#b7c9561e_0ad2_4558_9d49_d44368d2c6c6
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

COPASI78
notes: length of segment 8's unspliced mRNA encoding NS1 (nucleotides)
constant: true
value: 868.0
name: L8
type: Parameter

COPASI64
notes: fraction of fusion-competent virions (-)
constant: true
value: 0.51
name: Ffus
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_456f661b_56e8_421b_8d45_81ec41bf71a4
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#ecfb5c4d_d477_4294_9396_2d7000cb52eb
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

COPASI9
constant: false
in compartment: COPASI2
type: Species
initial amount: NaN
substance units: mole
boundary condition: false
name: Vfus
initial concentration: 0.0
has only substance units: false
notes: total amount of virions fused with endosomes (virions)

http://identifiers.org/biomodels.db/BIOMD0000000463#f8b732e8_5efe_4984_b6b9_d83be1d223f7
stoichiometry: 1.0
species: COPASI30
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#e4e374f4_2d2c_49a0_8561_124344b779f8
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

COPASI77
notes: length of segment 7's unspliced mRNA encoding M1 (nucleotides)
constant: true
value: 1005.0
name: L7
type: Parameter

COPASI63
notes: degradation rate of RdRp-cRNA and RdRp-vRNA complexes (1/h)
constant: true
value: 4.25
name: kDegRrdrp
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_0220a9aa_d4aa_42f4_a761_912ff50ef4c1
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI52
notes: synthesis rate of cRNAs (1/h)
constant: true
value: 1.38
name: kSynC
type: Parameter

COPASI42
notes: attachment rate of virus particles to high-affinity binding sites (1/(site*h))
constant: true
value: 0.0809
name: kAttHi
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_43c74df6_6959_453b_939d_7ef3de6bf071
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

COPASI62
notes: degradation rate of mRNA (1/h)
constant: true
value: 0.33
name: kDegM
type: Parameter

COPASI72
notes: length of segment 2's mRNA encoding PB1 (nucleotides)
constant: true
value: 2320.0
name: L2
type: Parameter

COPASI51
notes: synthesis rate of vRNAs (1/h)
constant: true
value: 13.86
name: kSynV
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_609368e1_0ea1_45d0_913f_d1e702f71c98
stoichiometry: 8.0
species: COPASI18
type: SpeciesReference

COPASI41
constant: false
in compartment: COPASI2
boundary condition: true
has only substance units: false
notes: total amount of vRNA in the cell considering an arbitrary segments (molecules)
initial amount: NaN
type: Species
substance units: mole
initial concentration: 0.0
name: total vRNA of a segment

COPASI30
constant: false
boundary condition: false
initial amount: NaN
initial concentration: 0.0
in compartment: COPASI2
has only substance units: false
name: P_Pb1
substance units: mole
notes: PB1 proteins (molecules)
type: Species

COPASI61
notes: degradation rate of RNPs (1/h)
constant: true
value: 0.09
name: kDegRnp
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#d29dd967_264f_4c18_bd38_c12b9f8eb966
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_408b74cf_a403_444a_b0ba_9171d0e49398
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#a92a6a25_dc57_4ed9_b71e_6a826555c311
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

COPASI71
notes: length of segment 1's mRNA encoding PB2 (nucleotides)
constant: true
value: 2320.0
name: L1
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#f74a6cbc_1634_408e_a20f_465e2a7fa2e2
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#e559f4ed_ec02_408d_8853_806b92301a0d
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_26223af9_04cf_43d6_9ad9_727297ef4a2d
exponent: 1.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

COPASI54
notes: binding rate of NP to RdRp-cRNA and RdRp-vRNA complexes (1/(h*molecule))
constant: true
value: 3.01E-4
name: kBindNp
type: Parameter

COPASI40
constant: false
initial concentration: 0.0
initial amount: NaN
substance units: mole
type: Species
name: total vRNA
in compartment: COPASI2
boundary condition: true
notes: total amount of vRNA in the cell considering all segments (molecules)
has only substance units: false

COPASI60
notes: degradation rate of nascent cRNA and vRNA (1/h)
constant: true
value: 36.36
name: kDegR
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_2e3d17ac_1f71_49b5_9fb6_18be63e1eaeb
stoichiometry: 1.0
species: COPASI26
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_77dd8446_2bd8_48fa_b482_60a4bae75d83
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

COPASI74
notes: length of segment 4's mRNA encoding HA (nucleotides)
constant: true
value: 1757.0
name: L4
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_91ae5662_25da_470e_b8bd_b39e4b4f3425
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

COPASI53
notes: binding rate of polymerase complexes to cRNA and vRNA (1/(h*molecule))
constant: true
value: 1.0
name: kBindRdrp
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#b555c7fe_f22e_4afa_82c6_cf152fc46c24
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

ORG:
  orgname: EMBL-EBI
n:
  given: Nick
  family: Juty

http://identifiers.org/biomodels.db/BIOMD0000000463#be4b925e_9443_4af6_9636_feed58819913
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

COPASI73
notes: length of segment 3's mRNA encoding PA (nucleotides)
constant: true
value: 2211.0
name: L3
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000463#_9696d47d_8224_4f82_b197_e7aa0635a902
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_13f0f680_9e93_4cbe_9a95_e9caf86ed513
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000463#_8a47b10a_8e35_485b_8424_e52e75d9f3b8
stoichiometry: 40.0
species: COPASI36
type: SpeciesReference

W3 CDTF: Wed Aug 07 14:32:58 BST 2013

orgname: EMBL-EBI

n:
  given: Vijayalakshmi
  family: Chelliah