COPASI273
type: Reaction
name: reaction29_12
is part of: GO:0002182
fast: false
reversible: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_545d6e9c_ae01_499e_9e53_fa7fed6df172
stoichiometry: 1.0
species: COPASI56
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_73f9caf1_1076_4331_80d6_6158d7adea5e
stoichiometry: 1.0
species: COPASI58
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b9e58d74_a7ea_4c9a_a435_f13b44ea12d8
stoichiometry: 1.0
species: COPASI139
type: SpeciesReference

COPASI85
initial amount: NaN
has only substance units: false
has part: P32324
type: Species
has part: CHEBI:2651
initial concentration: 0.0
boundary condition: false
in compartment: COPASI2
constant: false
has part: CHEBI:15996
name: 80S_aa-tRNA_eEF2_GTP_7

http://identifiers.org/biomodels.db/BIOMD0000000457#b8d6d041_0739_4b48_aeb0_f1b00276bbcc
stoichiometry: 1.0
species: COPASI165
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_50edfdab_1cb5_43d5_a223_b90e912599ec
stoichiometry: 1.0
species: COPASI127
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_87623e0c_1533_48c3_b754_9ba32c382804
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b69cdd06_a6a0_4194_8ce4_54586237965f
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#e5b2c9cf_878c_4645_a288_d612da6b4356
stoichiometry: 1.0
species: COPASI31
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b364ec0b_070e_4f5b_8b40_f0de1b4fd505
stoichiometry: 1.0
species: COPASI138
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#a6f37c88_4c87_4648_90c1_3529479c2ae4
stoichiometry: 1.0
species: COPASI166
type: SpeciesReference

COPASI129
has part: P16521
has part: GO:0022626
boundary condition: false
type: Species
has only substance units: false
initial amount: NaN
initial concentration: 0.0
name: 80S_tRNA_eEF3_GTP_14
has part: CHEBI:15996
in compartment: COPASI2
constant: false
has part: CHEBI:2651

COPASI272
name: reaction28_12
type: Reaction
reversible: false
fast: false
is part of: GO:0002182

COPASI83
name: 80S_aa-tRNA_eEF1A_GTP_7
boundary condition: false
has part: CHEBI:2651
initial amount: NaN
has only substance units: false
in compartment: COPASI2
has part: GO:0022626
has part: P02994
type: Species
initial concentration: 0.0
has part: CHEBI:15996
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000457#b8246f14_d1e6_4981_8463_b7f90ff843fd
value: 47.8215
name: k2
type: LocalParameter

COPASI179
notes: total concentration of mRNA that is not bound to any factor, ribosome sub-unit or 80S
constant: false
value: 7.16464328895E-7
name: mRNA_free
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_4971653c_0551_4e64_8876_f3bbf19462dd
stoichiometry: 1.0
species: COPASI55
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_508d4ebe_a8b4_4968_acf8_91c27bec345a
stoichiometry: 1.0
species: COPASI57
type: SpeciesReference

COPASI84
has part: CHEBI:2651
initial concentration: 0.0
boundary condition: false
in compartment: COPASI2
name: 80S_aa-tRNA_7
initial amount: NaN
has only substance units: false
type: Species
has part: GO:0022626
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_8a093a53_0f0e_4694_b5db_3df8538797ce
stoichiometry: 1.0
species: COPASI35
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_833826ab_a70c_4428_944f_03ae91026816
stoichiometry: 1.0
species: COPASI55
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_51303a0f_778f_43b4_a8b1_37298b2631f7
stoichiometry: 1.0
species: COPASI38
type: SpeciesReference

COPASI128
initial amount: NaN
boundary condition: false
constant: false
name: 80S_tRNA_14
initial concentration: 0.0
has part: GO:0022626
in compartment: COPASI2
has part: CHEBI:17843
has only substance units: false
type: Species

COPASI275
reversible: false
type: Reaction
is part of: GO:0002182
fast: false
name: reaction23_13

http://identifiers.org/biomodels.db/BIOMD0000000457#_97a879aa_81a0_4c8e_8fb3_4cf1d52563e1
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

COPASI82
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_7
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_1aa6030d_0597_4cad_b9ff_557aa955c4f9
stoichiometry: 1.0
species: COPASI80
type: SpeciesReference

COPASI127
boundary condition: false
has only substance units: false
has part: P32324
type: Species
initial concentration: 0.0
in compartment: COPASI2
has part: CHEBI:15996
initial amount: NaN
name: 80S_aa-tRNA_eEF2_GTP_14
has part: CHEBI:2651
constant: false

COPASI274
fast: false
type: Reaction
name: reaction22_13
reversible: true
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_113babbf_119d_4bef_934f_dbb80538fae1
stoichiometry: 1.0
species: COPASI26
type: SpeciesReference

COPASI81
boundary condition: false
has only substance units: false
has part: CHEBI:2651
constant: false
in compartment: COPASI2
name: 80S_tRNA_eEF3_GTP_6
has part: P16521
has part: GO:0022626
initial amount: NaN
initial concentration: 0.0
type: Species
has part: CHEBI:15996

http://identifiers.org/biomodels.db/BIOMD0000000457#_433f7b13_ed00_4864_99c5_cfc783128ba5
stoichiometry: 1.0
species: COPASI64
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_4b8c2614_0e83_4a5e_a748_486d5d13d16e
stoichiometry: 1.0
species: COPASI158
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_936faab3_e72c_4f54_ab82_af1c7d15a7ec
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

COPASI80
name: 80S_tRNA_6
has part: CHEBI:17843
initial concentration: 0.0
has only substance units: false
constant: false
has part: GO:0022626
initial amount: NaN
boundary condition: false
in compartment: COPASI2
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#d284e7d8_624d_407e_b9c0_2d4c6337b686
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_86129624_031c_49e3_a6e5_375c7a3964f2
stoichiometry: 1.0
species: COPASI67
type: SpeciesReference

COPASI176
constant: true
value: 2.24052E9
name: k28f
type: Parameter

COPASI277
fast: false
type: Reaction
name: reaction26_13
reversible: false
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_47857fda_c263_4859_8607_53b005e8a174
stoichiometry: 1.0
species: COPASI112
type: SpeciesReference

COPASI126
has part: CHEBI:2651
initial concentration: 0.0
has only substance units: false
has part: GO:0022626
initial amount: NaN
constant: false
name: 80S_aa-tRNA_14
boundary condition: false
type: Species
in compartment: COPASI2

COPASI175
constant: true
value: 2306950.0
name: k26f
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_9d4c0ed1_18fc_4241_8e8c_ec3c8bd1098a
stoichiometry: 1.0
species: COPASI89
type: SpeciesReference

COPASI276
fast: false
name: reaction25_13
type: Reaction
reversible: true
is part of: GO:0002182

COPASI125
type: Species
has part: CHEBI:15996
boundary condition: false
has only substance units: false
in compartment: COPASI2
has part: GO:0022626
initial amount: NaN
constant: false
has part: P02994
has part: CHEBI:2651
initial concentration: 0.0
name: 80S_aa-tRNA_eEF1A_GTP_14

http://identifiers.org/biomodels.db/BIOMD0000000457#d1115334_9bb6_4f80_914e_b71677543bd8
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

COPASI178
notes: total concentration of mRNA that is bound to any factor, ribosome sub-unit or 80S
constant: false
value: 0.0
name: mRNA_bound
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_410aa261_7e86_4100_b8c7_7630e7a90cae
stoichiometry: 1.0
species: COPASI156
type: SpeciesReference

COPASI279
fast: false
type: Reaction
is part of: GO:0002182
reversible: false
name: reaction29_13

COPASI124
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_14
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_3ba1e932_e981_4dd8_a6e9_f6110a984b8c
stoichiometry: 1.0
species: COPASI70
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_46dc5ff0_a4e3_4991_890a_8b043583aa01
stoichiometry: 1.0
species: COPASI91
type: SpeciesReference

COPASI177
constant: true
value: 72911.6740026381
name: k29f
type: Parameter

COPASI278
type: Reaction
fast: false
is part of: GO:0002182
reversible: false
name: reaction28_13

COPASI123
type: Species
has part: CHEBI:15996
name: 80S_tRNA_eEF3_GTP_13
has only substance units: false
boundary condition: false
in compartment: COPASI2
has part: GO:0022626
has part: P16521
has part: CHEBI:2651
initial amount: NaN
initial concentration: 0.0
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_5a4bfe5b_efbe_4454_9e75_476048ee9160
stoichiometry: 1.0
species: COPASI151
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#c139bca3_c419_4e1c_8aeb_70363809b119
stoichiometry: 1.0
species: COPASI92
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b8dd0227_976a_46ef_83dd_a886f7ce03bd
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

COPASI172
constant: true
value: 28324.3562938545
name: k23f
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#f081378a_cfc7_4f5e_8de0_ea53489406b0
stoichiometry: 1.0
species: COPASI122
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#fc828231_16ec_44ea_9c10_c98e0ab53f17
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI321
type: Reaction
reversible: false
fast: false
is part of: GO:0002184
name: reaction33

http://identifiers.org/biomodels.db/BIOMD0000000457#_2f7087a7_98f7_4b26_80e5_a421dadfc60b
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_9a7eebfe_df41_43be_8e6f_3edc4a472789
stoichiometry: 1.0
species: COPASI96
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_3e464291_8b5c_41d2_b9fd_cd814ac69f41
value: 14.2912
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#ed9e97d3_2163_4f3e_80e9_499f38faae54
stoichiometry: 1.0
species: COPASI94
type: SpeciesReference

COPASI171
constant: true
value: 0.284007213965168
name: k22b
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_1ef18b9a_0265_437f_818b_deeaf0305c2b
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

COPASI174
constant: true
value: 0.00322599
name: k25b
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#b4e2d480_2e1f_4112_b9de_5b45aa982ecd
stoichiometry: 1.0
species: COPASI160
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_472c1590_225b_48a5_ae97_88075fdd7869
stoichiometry: 1.0
species: COPASI82
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_57443adc_8802_4e0e_94d4_02007fe68ee4
stoichiometry: 1.0
species: COPASI73
type: SpeciesReference

COPASI173
constant: true
value: 3.10377169466493E9
name: k25f
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#f56f2e97_e8e0_4144_bb76_04311f03a50d
stoichiometry: 1.0
species: COPASI72
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#ef782747_c1a0_40d2_a1c3_f7c5ae88d890
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_8d601a34_da17_47b9_91bf_fafe0131f9c9
value: 2.70026
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#f327e07f_bd64_4afa_8c46_11fdf4df39e6
stoichiometry: 1.0
species: COPASI106
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_3d1f4b39_4224_406a_bfc0_85c07417a6b9
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f45702c2_58cd_405f_9124_22e073570b7f
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_6d738f3c_dfb4_49aa_8726_bfb5d6302e85
stoichiometry: 1.0
species: COPASI66
type: SpeciesReference

COPASI230
fast: false
is part of: GO:0002182
reversible: false
type: Reaction
name: reaction28_5

http://identifiers.org/biomodels.db/BIOMD0000000457#_9880ef8d_d10a_4bbf_8b12_7d32fba3f4c9
stoichiometry: 1.0
species: COPASI72
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_98fc05b5_8501_4dd7_87f7_b64bea70dbb0
stoichiometry: 1.0
species: COPASI123
type: SpeciesReference

COPASI271
reversible: false
fast: false
type: Reaction
is part of: GO:0002182
name: reaction26_12

http://identifiers.org/biomodels.db/BIOMD0000000457#_409267c2_1ad4_47bf_a9a0_bd8fe4d0cf25
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#cbce4a75_1a91_4950_9c58_7585f132dc80
stoichiometry: 1.0
species: COPASI121
type: SpeciesReference

COPASI170
constant: true
value: 8.10035535716195E9
name: k22f
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#f8e9fbd3_e133_4707_9580_4eabec1fd39f
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f59a9cbd_1903_4de6_9f27_ec8c010e7470
stoichiometry: 1.0
species: COPASI124
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_6778ef61_f28c_4d1b_a5da_ebcc06ccd7d6
value: 1.97254E7
name: k1
type: LocalParameter

COPASI231
fast: false
is part of: GO:0002182
name: reaction29_5
reversible: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#b7aebb7b_7030_44bf_b223_d630750197d8
value: 3.97698
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#ec98fd68_93b4_4f70_be02_08563bcdc4c1
stoichiometry: 1.0
species: COPASI51
type: SpeciesReference

COPASI270
reversible: true
type: Reaction
name: reaction25_12
fast: false
is part of: GO:0002182

COPASI320
reversible: false
is part of: GO:0002184
name: reaction32
fast: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_193565c6_429c_4bbd_853f_7dbbd8621be5
stoichiometry: 1.0
species: COPASI149
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#ad45e2ee_fe12_477e_9452_7277543944a1
stoichiometry: 1.0
species: COPASI120
type: SpeciesReference

COPASI33
type: Species
in compartment: COPASI2
initial concentration: 1.9450064193577E-7
has part: CHEBI:17552
boundary condition: false
has only substance units: false
constant: false
has part: P39730
name: eIF5B_GDP
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000457#e02ff3e4_e2df_4b6a_8bd0_7a6f37079edd
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

COPASI221
name: reaction23_4
reversible: false
type: Reaction
fast: false
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_9055c7e1_3670_4524_984e_0c415dddc4ac
value: 1977.92
name: k2
type: LocalParameter

COPASI32
constant: false
has part: P06634
name: 48S_Ded1
type: Species
initial amount: NaN
has only substance units: false
initial concentration: 0.0
in compartment: COPASI2
boundary condition: false
has part: GO:0033290

http://identifiers.org/biomodels.db/BIOMD0000000457#fef2ead6_30e8_4b65_b7d4_3d45e4b15de0
stoichiometry: 1.0
species: COPASI48
type: SpeciesReference

COPASI220
reversible: true
fast: false
is part of: GO:0002182
name: reaction22_4
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#fe03ceab_1857_41c0_be03_a72ba88b9177
value: 1.2395
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_61101e7a_c732_4206_8dfc_567475ebabf2
stoichiometry: 1.0
species: COPASI125
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_6eaaed2f_8ff8_4294_a4b8_8557fb832247
stoichiometry: 1.0
species: COPASI125
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_0d0508ed_4051_4b04_b18d_f2bcd8707019
stoichiometry: 1.0
species: COPASI88
type: SpeciesReference

COPASI31
is: P06634
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.13458707795866E-6
initial amount: NaN
in compartment: COPASI2
name: Ded1
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#c393eeee_9fdf_4cbb_8ba1_1425a1cff493
stoichiometry: 1.0
species: COPASI119
type: SpeciesReference

COPASI223
type: Reaction
reversible: false
name: reaction26_4
fast: false
is part of: GO:0002182

COPASI30
is: GO:0033290
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 48S
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_0f6ab946_5682_4a59_88e4_4962dfb80390
stoichiometry: 1.0
species: COPASI91
type: SpeciesReference

COPASI222
is part of: GO:0002182
name: reaction25_4
type: Reaction
reversible: true
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#b32045ae_8554_4dce_860e_7ccf18db2a73
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#fa1bd53b_3529_4d69_9e06_58f0259cd4e0
stoichiometry: 1.0
species: COPASI83
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#ab7ad69e_9812_4a24_a180_2cebf1bd7888
stoichiometry: 1.0
species: COPASI159
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_434ed41c_20a6_479b_ab2f_66f908673065
stoichiometry: 1.0
species: COPASI112
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_2f221629_0307_4adc_9b7d_f850b09dfc01
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b5b6d50f_45dc_4e23_ae36_c6a8421a07bd
stoichiometry: 1.0
species: COPASI142
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_374e0a45_5c24_430a_aa3e_b222bc390290
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_2997bbab_c7b1_4793_b67f_c4f0e7e7f2ff
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_69a9d581_32cc_4be6_ae3f_4bbd74e31fde
stoichiometry: 1.0
species: COPASI50
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_386bfbc3_7b49_41f5_9164_aa8857505783
stoichiometry: 1.0
species: COPASI83
type: SpeciesReference

COPASI225
reversible: false
fast: false
name: reaction29_4
type: Reaction
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_47e27556_4719_4819_b37d_50fdf73be303
stoichiometry: 1.0
species: COPASI60
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI164
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_71ab9d36_ced8_4a65_a52b_261508321439
stoichiometry: 1.0
species: COPASI132
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d96895a5_d075_4fc0_8806_99f428092546
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_45070242_e3b8_47d3_a1f3_a1754764f181
stoichiometry: 1.0
species: COPASI108
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_191f0fd4_d5be_44c4_a022_de2fb698988f
value: 304.768
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#fdd44758_893d_4394_a427_b1a6d6f31a06
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

COPASI224
is part of: GO:0002182
name: reaction28_4
reversible: false
fast: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#d6216f62_7986_4985_bc7f_2e8cb0097b04
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_4d2fc37a_b7a4_4a65_ac52_368a6c73000e
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

COPASI227
type: Reaction
fast: false
reversible: false
is part of: GO:0002182
name: reaction23_5

http://identifiers.org/biomodels.db/BIOMD0000000457#_2fc9c1e7_568e_4920_9cd2_c4cd47287870
stoichiometry: 1.0
species: COPASI167
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_751ba716_8544_4979_bc81_009e3f447ddc
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#afbcc385_5743_4da9_a094_f3067f854c59
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_01fd1d29_8088_4159_8ff3_aa6b3c10ead6
stoichiometry: 1.0
species: COPASI165
type: SpeciesReference

COPASI226
reversible: true
fast: false
name: reaction22_5
type: Reaction
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_650b716e_1e4c_4525_a96c_32a52a39c799
value: 45.4082
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#e9aef5e5_1ee5_43cd_ae2a_980e4affe9cc
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI158
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_0490748d_47f7_43f1_a841_670adc0c2124
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d5620ab2_82ee_49d2_8edc_6d3bc538a23d
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI77
type: SpeciesReference

COPASI133
boundary condition: false
constant: false
name: 80S_aa-tRNA_eEF2_GTP_15
initial concentration: 0.0
initial amount: NaN
has part: CHEBI:15996
type: Species
in compartment: COPASI2
has only substance units: false
has part: P32324
has part: CHEBI:2651

http://identifiers.org/biomodels.db/BIOMD0000000457#_675e406b_1ef6_40d5_bfa2_858098ea0897
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI81
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_99372e57_8ae9_49ac_82ba_976ae87448f6
value: 13.295
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_019897f0_a897_4159_8a26_9250ccc2e013
value: 34.8025
name: k2
type: LocalParameter

COPASI268
type: Reaction
fast: false
reversible: true
name: reaction22_12
is part of: GO:0002182

COPASI229
reversible: false
is part of: GO:0002182
fast: false
name: reaction26_5
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#e58367f3_c52a_425e_9353_6bf7f17d9d59
stoichiometry: 1.0
species: COPASI87
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_9745cc75_454c_4ae3_969f_42bdef9c701c
stoichiometry: 1.0
species: COPASI75
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_6a65527d_6890_4fe3_ba76_608093dcf283
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_3c68c6ac_3d92_4521_a955_83d52e6f9177
stoichiometry: 1.0
species: COPASI56
type: SpeciesReference

COPASI134
in compartment: COPASI2
type: Species
has part: GO:0022626
initial concentration: 0.0
name: 80S_tRNA_15
has part: CHEBI:17843
has only substance units: false
initial amount: NaN
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_56572772_40f4_45d0_a49f_2250f5c77798
stoichiometry: 1.0
species: COPASI146
type: SpeciesReference

COPASI269
is part of: GO:0002182
reversible: false
fast: false
type: Reaction
name: reaction23_12

COPASI228
name: reaction25_5
reversible: true
fast: false
type: Reaction
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_6584002b_1e2d_4633_a6ee_077088092f01
stoichiometry: 1.0
species: COPASI100
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d11a81f1_aac5_47f3_bf19_f247b582a422
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI78
initial amount: NaN
initial concentration: 0.0
boundary condition: false
has part: GO:0022626
name: 80S_aa-tRNA_6
type: Species
has part: CHEBI:2651
constant: false
in compartment: COPASI2
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_4925342d_68d9_4c45_bf4a_9c1e95d28788
stoichiometry: 1.0
species: COPASI117
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_5d52408a_601a_440c_93f5_334527a8dc42
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

COPASI131
has part: P02994
boundary condition: false
has part: GO:0022626
constant: false
initial concentration: 0.0
has only substance units: false
has part: CHEBI:15996
in compartment: COPASI2
type: Species
initial amount: NaN
name: 80S_aa-tRNA_eEF1A_GTP_15
has part: CHEBI:2651

http://identifiers.org/biomodels.db/BIOMD0000000457#_4f46cef2_39bc_4fe1_831c_ac1ee3ddd005
stoichiometry: 1.0
species: COPASI102
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_21aad9e5_fd6e_4fe3_a330_f290157328dd
stoichiometry: 1.0
species: COPASI147
type: SpeciesReference

COPASI39
has part: P02994
boundary condition: false
has part: P32471
constant: false
initial concentration: 0.0
name: eEF1A_GDP_eEF1B
in compartment: COPASI2
type: Species
is part of: GO:0005853
has only substance units: false
initial amount: NaN
has part: CHEBI:17552
has part: P36008
has part: P29547

COPASI79
constant: false
initial amount: NaN
boundary condition: false
initial concentration: 0.0
has only substance units: false
name: 80S_aa-tRNA_eEF2_GTP_6
has part: CHEBI:15996
type: Species
has part: CHEBI:2651
in compartment: COPASI2
has part: P32324

http://identifiers.org/biomodels.db/BIOMD0000000457#_0f554ca6_c139_44a7_8df6_95a089cf1e53
stoichiometry: 1.0
species: COPASI51
type: SpeciesReference

COPASI132
initial concentration: 0.0
in compartment: COPASI2
constant: false
name: 80S_aa-tRNA_15
has part: CHEBI:2651
has part: GO:0022626
type: Species
initial amount: NaN
has only substance units: false
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_49e2e9d3_7cf1_4f01_a2ec_5c54cf90ad95
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_1a9689fa_9c4d_4d13_8f3b_cdccfb00606a
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_60de651d_36d7_460e_aafd_04e3eeed2e2b
stoichiometry: 1.0
species: COPASI114
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f0db637d_02be_4540_a466_594abee5e98a
stoichiometry: 1.0
species: COPASI95
type: SpeciesReference

COPASI38
has part: P36008
has part: GO:0005853
name: eEF1B
constant: false
boundary condition: false
has only substance units: false
type: Species
in compartment: COPASI2
initial amount: NaN
has part: P29547
initial concentration: 3.20115639852622E-6
has part: P32471

http://identifiers.org/biomodels.db/BIOMD0000000457#_06e4114a_b2d7_4dc2_9a09_95663aeadf6a
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_8b8d260b_b926_4fad_9ef1_4489436c6e37
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI76
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_6
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#d62e21d5_2f0c_4d7f_a31b_23b2b7817c8d
value: 3.5208E14
name: k1
type: LocalParameter

COPASI37
in compartment: COPASI2
has only substance units: false
constant: false
type: Species
has part: GO:0005853
name: eEF1A_GDP
boundary condition: false
initial amount: NaN
initial concentration: 4.05209670699521E-5
has part: CHEBI:17552
has part: P02994

http://identifiers.org/biomodels.db/BIOMD0000000457#b43f92e4_b360_4930_a0f3_08afa2fefc62
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_3a2001ab_a5c9_4faa_bb20_fe2e304b0743
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

COPASI130
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_15
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_1f61d1b5_bfdf_430c_87db_306fb0fedbff
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#df5e971f_0953_4112_93b5_45252c0322a5
stoichiometry: 1.0
species: COPASI168
type: SpeciesReference

COPASI77
has only substance units: false
constant: false
name: 80S_aa-tRNA_eEF1A_GTP_6
initial amount: NaN
has part: CHEBI:15996
has part: CHEBI:2651
in compartment: COPASI2
has part: GO:0022626
has part: P02994
boundary condition: false
initial concentration: 0.0
type: Species

COPASI36
is: GO:0015934
constant: false
boundary condition: false
has only substance units: false
initial concentration: 7.6989833745501E-6
initial amount: NaN
in compartment: COPASI2
name: 60S
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_6fda06ec_1e51_47b1_8ff0_12321994baad
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d8b65799_4e4b_4e72_8bd0_20b4555caa62
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#fe8cb6a9_c203_41a8_93e0_43d689ba902b
stoichiometry: 1.0
species: COPASI143
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f30fa866_c89a_4594_a261_c349f1818d6d
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

COPASI74
in compartment: COPASI2
has only substance units: false
initial amount: NaN
boundary condition: false
type: Species
has part: GO:0022626
constant: false
initial concentration: 0.0
name: 80S_tRNA_5
has part: CHEBI:17843

http://identifiers.org/biomodels.db/BIOMD0000000457#b946657c_ab14_4cf3_b0ab_eb7d6fe8fbc2
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

COPASI35
has part: GO:0033290
initial amount: NaN
boundary condition: false
type: Species
has part: P06634
in compartment: COPASI2
has part: P39730
has only substance units: false
has part: CHEBI:15996
name: 48S_Ded1_eIF5B_GTP
initial concentration: 0.0
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_3b2c702b_ee9f_4f3a_b0ce_85621b999b4a
stoichiometry: 1.0
species: COPASI124
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b9bd622a_1c3b_4246_b1e6_e2d548168918
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_82486c2f_a4cf_404d_aca0_2f25115a6349
stoichiometry: 1.0
species: COPASI58
type: SpeciesReference

COPASI75
boundary condition: false
has only substance units: false
initial amount: NaN
type: Species
name: 80S_tRNA_eEF3_GTP_5
has part: P16521
has part: CHEBI:15996
has part: CHEBI:2651
initial concentration: 0.0
in compartment: COPASI2
constant: false
has part: GO:0022626

http://identifiers.org/biomodels.db/BIOMD0000000457#fa37f2b6_58ae_4e26_9829_99c74bf2e3a6
stoichiometry: 1.0
species: COPASI77
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_6b1a8f87_cc0e_4806_970f_441f921c506c
stoichiometry: 1.0
species: COPASI137
type: SpeciesReference

COPASI34
initial concentration: 0.0
name: eIF5B_GTP
type: Species
has part: P39730
boundary condition: false
has only substance units: false
has part: CHEBI:15996
in compartment: COPASI2
constant: false
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000457#_19883c2d_ec89_4d38_9a5c_42e02006e1ee
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

COPASI70
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_5
type: Species

COPASI116
type: Species
name: 80S_tRNA_12
initial amount: NaN
boundary condition: false
constant: false
has part: CHEBI:17843
has only substance units: false
initial concentration: 0.0
has part: GO:0022626
in compartment: COPASI2

COPASI287
name: reaction23_15
type: Reaction
is part of: GO:0002182
fast: false
reversible: false

http://identifiers.org/biomodels.db/BIOMD0000000457#c2d57c18_bdf9_47ed_9c4a_a28f5539518d
stoichiometry: 1.0
species: COPASI102
type: SpeciesReference

COPASI319
type: Reaction
fast: false
reversible: true
is part of: GO:0002184
name: reaction31

http://identifiers.org/biomodels.db/BIOMD0000000457#ab5b50c5_d5e0_449b_a025_cc3308fc3d49
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#ea5ac519_2554_494b_9be7_6c84cfdcd5a5
stoichiometry: 1.0
species: COPASI98
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#ef3dd2b1_f399_42a0_85c9_d0aea8d0fc4c
stoichiometry: 1.0
species: COPASI166
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_66c55067_bf9c_47e8_a3bd_1da2a4fc7390
value: 5026500.0
name: k1
type: LocalParameter

COPASI169
notes: concentration of total mRNA
has part: P39936
has part: P39935
constant: true
value: 7.16464328895E-7
name: mRNA_tot
type: Parameter

COPASI286
is part of: GO:0002182
reversible: true
fast: false
type: Reaction
name: reaction22_15

COPASI115
constant: false
boundary condition: false
in compartment: COPASI2
type: Species
has part: CHEBI:2651
name: 80S_aa-tRNA_eEF2_GTP_12
initial concentration: 0.0
has part: CHEBI:15996
has part: P32324
initial amount: NaN
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_76c13170_68b2_4501_8ac1_8f3bf4258e79
stoichiometry: 1.0
species: COPASI138
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d86794e4_29da_4d52_9123_e056d1cd1ed9
value: 18032.6
name: k2
type: LocalParameter

COPASI168
initial amount: NaN
has part: CHEBI:33699
type: Species
name: eIF4A_eIF4E_eIF4G_mRNA_Pab1
initial concentration: 0.0
has only substance units: false
constant: false
has part: P39935
in compartment: COPASI2
has part: P07260
boundary condition: false
has part: P10081
has part: P39936

COPASI72
has part: GO:0022626
boundary condition: false
type: Species
has part: CHEBI:2651
constant: false
in compartment: COPASI2
initial amount: NaN
has only substance units: false
name: 80S_aa-tRNA_5
initial concentration: 0.0

http://identifiers.org/biomodels.db/BIOMD0000000457#ef0b5fbc_f438_4231_b0a0_88a1d76c813f
stoichiometry: 1.0
species: COPASI133
type: SpeciesReference

COPASI285
type: Reaction
is part of: GO:0002182
name: reaction29_14
fast: false
reversible: false

COPASI118
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_13
type: Species

COPASI317
name: reaction29_20
reversible: false
type: Reaction
is part of: GO:0002182
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#fd94c19c_7650_4ba8_8180_95bada88eb57
stoichiometry: 1.0
species: COPASI99
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_15b88a38_2559_4efc_b1cc_b585b02e8dd1
value: 3.5491E9
name: k1
type: LocalParameter

COPASI9
name: eIF3
initial amount: NaN
constant: false
type: Species
is: GO:0005852
has part: P40217
in compartment: COPASI2
boundary condition: false
has part: Q04067
initial concentration: 9.31982242608899E-7
has only substance units: false
has part: P32497
has part: P06103
has part: P38249

COPASI73
initial amount: NaN
has only substance units: false
has part: P32324
type: Species
boundary condition: false
name: 80S_aa-tRNA_eEF2_GTP_5
constant: false
has part: CHEBI:2651
initial concentration: 0.0
in compartment: COPASI2
has part: CHEBI:15996

http://identifiers.org/biomodels.db/BIOMD0000000457#a22d0264_9cc3_4581_9552_af877014f2e8
stoichiometry: 1.0
species: COPASI104
type: SpeciesReference

COPASI71
has only substance units: false
initial amount: NaN
name: 80S_aa-tRNA_eEF1A_GTP_5
has part: CHEBI:2651
has part: P02994
in compartment: COPASI2
has part: GO:0022626
type: Species
initial concentration: 0.0
has part: CHEBI:15996
constant: false
boundary condition: false

COPASI167
initial concentration: 0.0
has part: CHEBI:15996
initial amount: NaN
in compartment: COPASI2
boundary condition: false
type: Species
has only substance units: false
constant: false
has part: GO:0022626
has part: P12385
name: 80S_eRF1_eRF3_GTP

http://identifiers.org/biomodels.db/BIOMD0000000457#_15759901_b103_469e_8efe_c1af586f9744
stoichiometry: 1.0
species: COPASI78
type: SpeciesReference

COPASI284
name: reaction28_14
is part of: GO:0002182
fast: false
reversible: false
type: Reaction

COPASI117
in compartment: COPASI2
has part: CHEBI:15996
constant: false
has part: CHEBI:2651
has part: P16521
boundary condition: false
has only substance units: false
has part: GO:0022626
name: 80S_tRNA_eEF3_GTP_12
type: Species
initial amount: NaN
initial concentration: 0.0

COPASI318
type: Reaction
reversible: true
is part of: GO:0002184
name: reaction30
fast: false

COPASI8
has only substance units: false
has part: CHEBI:29173
name: eIF2_GTP_Met-tRNA
has part: GO:0044207
has part: CHEBI:15996
in compartment: COPASI2
initial amount: NaN
constant: false
boundary condition: false
has part: GO:0005850
type: Species
initial concentration: 0.0

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stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI46
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COPASI166
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type: Species
initial concentration: 0.0
initial amount: NaN
name: eRF1_eRF3_GTP
constant: false
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has part: P05453
in compartment: COPASI2
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boundary condition: false

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stoichiometry: 1.0
species: COPASI84
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI85
type: SpeciesReference

COPASI315
type: Reaction
reversible: false
is part of: GO:0002182
name: reaction29_19
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#c8443caa_abdf_4982_93a4_dab0cf5bea9a
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

COPASI112
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_12
type: Species

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stoichiometry: 1.0
species: COPASI38
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COPASI165
is: P12385
constant: false
boundary condition: false
has only substance units: false
initial concentration: 8.91461275538947E-7
initial amount: NaN
in compartment: COPASI2
name: eRF1
type: Species

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stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

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value: 3865650.0
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#dcf4c670_4c45_40cd_a5a8_acd152ee835b
stoichiometry: 1.0
species: COPASI87
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COPASI316
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reversible: false
type: Reaction
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fast: false

COPASI111
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has only substance units: false
boundary condition: false
initial amount: NaN
initial concentration: 0.0
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type: Species
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constant: false

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stoichiometry: 1.0
species: COPASI131
type: SpeciesReference

COPASI289
fast: false
type: Reaction
reversible: false
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COPASI313
fast: false
type: Reaction
reversible: false
is part of: GO:0002182
name: reaction26_19

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stoichiometry: 1.0
species: COPASI117
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COPASI164
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initial amount: NaN
constant: false
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boundary condition: false
name: eRF3_GTP

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stoichiometry: 1.0
species: COPASI134
type: SpeciesReference

COPASI114
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initial amount: NaN
initial concentration: 0.0
constant: false
has part: GO:0022626
name: 80S_aa-tRNA_12
boundary condition: false
type: Species
in compartment: COPASI2

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stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

COPASI288
is part of: GO:0002182
name: reaction25_15
type: Reaction
fast: false
reversible: true

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stoichiometry: 1.0
species: COPASI41
type: SpeciesReference

COPASI163
initial concentration: 5.6729353897933E-7
type: Species
in compartment: COPASI2
has version: P05453
boundary condition: false
has part: CHEBI:17552
initial amount: NaN
name: eRF3_GDP
constant: false
has only substance units: false

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stoichiometry: 1.0
species: COPASI153
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI128
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stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

COPASI113
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in compartment: COPASI2
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has part: GO:0022626
initial amount: NaN
constant: false
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initial concentration: 0.0
has part: CHEBI:15996
type: Species
boundary condition: false
has only substance units: false

COPASI314
name: reaction28_19
type: Reaction
is part of: GO:0002182
fast: false
reversible: false

http://identifiers.org/biomodels.db/BIOMD0000000457#e625fcdf_03cb_4b59_b76a_f2dd16071af9
stoichiometry: 1.0
species: COPASI30
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d860aeeb_0558_42f0_a132_3b30c38809b4
stoichiometry: 1.0
species: COPASI84
type: SpeciesReference

COPASI162
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initial amount: NaN
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has part: CHEBI:2651
name: 80S_tRNA_eEF3_GTP_20
boundary condition: false
type: Species
constant: false
has part: CHEBI:15996
initial concentration: 0.0
has part: GO:0022626
in compartment: COPASI2

http://identifiers.org/biomodels.db/BIOMD0000000457#_55ef0761_ee9c_4024_9b37_f90670a8e783
stoichiometry: 1.0
species: COPASI141
type: SpeciesReference

COPASI311
reversible: false
fast: false
type: Reaction
is part of: GO:0002182
name: reaction23_19

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stoichiometry: 1.0
species: COPASI116
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI157
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI144
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI54
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COPASI312
fast: false
name: reaction25_19
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reversible: true
type: Reaction

COPASI161
boundary condition: false
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name: 80S_tRNA_20
has only substance units: false
initial amount: NaN
initial concentration: 0.0
has part: CHEBI:17843
in compartment: COPASI2
type: Species
constant: false

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stoichiometry: 1.0
species: COPASI154
type: SpeciesReference

COPASI160
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constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_20
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_0037be07_fb78_46f1_929f_0722b1071d04
stoichiometry: 1.0
species: COPASI156
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_07d93f87_e498_49db_aa48_f8c2f13521bf
stoichiometry: 1.0
species: COPASI107
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI133
type: SpeciesReference

COPASI310
fast: false
reversible: true
is part of: GO:0002182
name: reaction22_19
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_44e72a01_1622_4522_830e_a3ed5b96536d
value: 1.96096E7
name: k1
type: LocalParameter

COPASI242
reversible: false
type: Reaction
name: reaction28_7
fast: false
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_0a1c78b6_9673_4da3_8175_702996296f2e
stoichiometry: 1.0
species: COPASI61
type: SpeciesReference

ORG:
  orgname: University of Manchester
n:
  given: Pedro
  family: Mendes

http://identifiers.org/biomodels.db/BIOMD0000000457#_4659325a_a9c9_458a_8b1e_8c1410019a0c
stoichiometry: 1.0
species: COPASI111
type: SpeciesReference

COPASI283
fast: false
type: Reaction
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name: reaction26_14
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http://identifiers.org/biomodels.db/BIOMD0000000457#_4d2a8488_eafe_4a87_a617_3ab38211b939
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

COPASI243
type: Reaction
fast: false
is part of: GO:0002182
reversible: false
name: reaction29_7

http://identifiers.org/biomodels.db/BIOMD0000000457#_46c76dae_5cde_416a_896e_9b9752dca2b7
stoichiometry: 1.0
species: COPASI46
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stoichiometry: 1.0
species: COPASI53
type: SpeciesReference

COPASI119
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has part: GO:0022626
initial amount: NaN
boundary condition: false
initial concentration: 0.0
in compartment: COPASI2
constant: false
has part: CHEBI:2651
name: 80S_aa-tRNA_eEF1A_GTP_13
has only substance units: false
has part: P02994

http://identifiers.org/biomodels.db/BIOMD0000000457#e1cc7e67_81cc_40f7_a3b7_28779300bccc
stoichiometry: 1.0
species: COPASI8
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http://identifiers.org/biomodels.db/BIOMD0000000457#f7d4804f_586f_4f35_95ee_e9fb608cc9f7
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

COPASI282
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reversible: true
type: Reaction
fast: false

COPASI240
is part of: GO:0002182
name: reaction25_7
type: Reaction
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fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_18157d4c_3d70_4b5d_bef1_1323b91f9567
stoichiometry: 1.0
species: COPASI70
type: SpeciesReference

COPASI281
fast: false
type: Reaction
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reversible: false
name: reaction23_14

http://identifiers.org/biomodels.db/BIOMD0000000457#b70ec1fc_60ad_4c31_9df5_490c4fdacd2f
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

COPASI241
name: reaction26_7
fast: false
type: Reaction
reversible: false
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#a6c9e60a_7023_479a_b02e_9d496ae55003
value: 2.00245E7
name: k1
type: LocalParameter

COPASI280
name: reaction22_14
is part of: GO:0002182
reversible: true
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_086d6bf2_ecea_4011_8b6c_ad636c2991a2
stoichiometry: 1.0
species: COPASI74
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_77f44db3_2d14_412e_8863_fef9c49f0311
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

COPASI235
is part of: GO:0002182
fast: false
reversible: false
type: Reaction
name: reaction26_6

http://identifiers.org/biomodels.db/BIOMD0000000457#_93eac681_4f8e_4376_8c27_33f5168bf25e
stoichiometry: 1.0
species: COPASI68
type: SpeciesReference

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value: 0.406929
name: k2
type: LocalParameter

COPASI234
is part of: GO:0002182
name: reaction25_6
reversible: true
fast: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_86260ce8_2517_4ab0_9abf_8ede8cc81942
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI5
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COPASI21
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boundary condition: false
initial concentration: 0.0
in compartment: COPASI2
initial amount: NaN
name: eIF4E_eIF4G
has only substance units: false
type: Species
has part: P07260
constant: false
has part: P39935

http://identifiers.org/biomodels.db/BIOMD0000000457#c2b996ad_fe3f_4880_9add_bc65dfee01fb
stoichiometry: 1.0
species: COPASI98
type: SpeciesReference

COPASI233
type: Reaction
is part of: GO:0002182
fast: false
reversible: false
name: reaction23_6

http://identifiers.org/biomodels.db/BIOMD0000000457#_2cd39f14_a331_470d_bb94_2b9e4d81ec3f
value: 8.7134E10
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_8e984632_d799_4d5f_981f_60f618f284b5
stoichiometry: 1.0
species: COPASI44
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COPASI20
constant: false
name: eIF4G
initial amount: NaN
has only substance units: false
has part: P39935
type: Species
initial concentration: 8.91461275538947E-7
has part: P39936
boundary condition: false
in compartment: COPASI2

http://identifiers.org/biomodels.db/BIOMD0000000457#_28431bc0_b6e4_4293_9011_96a5e7004fce
stoichiometry: 1.0
species: COPASI71
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_151d9563_d771_4838_8e4e_6bafbe829db8
stoichiometry: 1.0
species: COPASI97
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f22ea6e2_af23_45ec_ab9c_8e4ccad75c15
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_31820c3e_3662_4da4_aec7_0086227e1def
stoichiometry: 1.0
species: COPASI151
type: SpeciesReference

COPASI232
type: Reaction
reversible: true
name: reaction22_6
fast: false
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_8929df4d_a2e2_449e_ba92_ab0a04eb74e5
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#eb0db633_4aef_4788_a980_5eddb85bb093
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

COPASI239
is part of: GO:0002182
reversible: false
type: Reaction
name: reaction23_7
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#de1e0c47_9803_484c_b548_afaf41a174ee
stoichiometry: 1.0
species: COPASI52
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_19bbd1f8_0a19_4cdf_a70f_79325032bcc3
stoichiometry: 1.0
species: COPASI126
type: SpeciesReference

W3 CDTF: Fri Jun 21 12:28:41 BST 2013

http://identifiers.org/biomodels.db/BIOMD0000000457#_6386f691_4354_4332_a599_d180f89b5175
stoichiometry: 1.0
species: COPASI115
type: SpeciesReference

COPASI238
reversible: true
fast: false
is part of: GO:0002182
type: Reaction
name: reaction22_7

http://identifiers.org/biomodels.db/BIOMD0000000457#_1de5679b_eb93_442c_a609_ce9f34904055
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#fe0e7e86_e77b_4097_9bfa_28c08845c84a
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#daf3c1a8_3746_47b0_a73a_85bcbf4c3442
stoichiometry: 1.0
species: COPASI134
type: SpeciesReference

W3 CDTF: Sat Apr 30 22:53:18 BST 2011

http://identifiers.org/biomodels.db/BIOMD0000000457#_5bc44d4e_b0f2_4fbd_966c_6b09217a67ac
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

COPASI237
reversible: false
is part of: GO:0002182
name: reaction29_6
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#fc528f6d_92ea_4e98_be30_ae1aff819a3f
stoichiometry: 1.0
species: COPASI142
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_5804fdee_d584_4bac_a660_b123036aca10
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_0a13d224_56de_4ae9_9df8_4498addb801e
value: 1.80542
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#c88c4448_7b9b_4787_8853_de4f27444938
value: 0.00774034
name: k2
type: LocalParameter

COPASI236
is part of: GO:0002182
reversible: false
fast: false
type: Reaction
name: reaction28_6

http://identifiers.org/biomodels.db/BIOMD0000000457#ed746618_0624_44e9_9353_4e676ddad260
stoichiometry: 1.0
species: COPASI90
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#fc4de251_5814_4c0b_9312_fcf1e3afbaf5
value: 814356.0
name: k1
type: LocalParameter

COPASI66
boundary condition: false
name: 80S_aa-tRNA_4
initial concentration: 0.0
has part: GO:0022626
type: Species
constant: false
has only substance units: false
has part: CHEBI:2651
initial amount: NaN
in compartment: COPASI2

COPASI27
is: P34167
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.13458707795866E-6
initial amount: NaN
in compartment: COPASI2
name: eIF4B
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#bd5abdfe_5b29_4723_a4ac_46d7458d7191
stoichiometry: 1.0
species: COPASI33
type: SpeciesReference

COPASI120
has only substance units: false
has part: CHEBI:2651
has part: GO:0022626
initial amount: NaN
boundary condition: false
type: Species
name: 80S_aa-tRNA_13
initial concentration: 0.0
in compartment: COPASI2
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_691ce170_f951_4132_af8d_ae77afebe4f7
stoichiometry: 1.0
species: COPASI69
type: SpeciesReference

COPASI67
has part: CHEBI:2651
in compartment: COPASI2
type: Species
has part: P32324
name: 80S_aa-tRNA_eEF2_GTP_4
boundary condition: false
constant: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
has part: CHEBI:15996

COPASI26
is: P10081
constant: false
boundary condition: false
has only substance units: false
initial concentration: 9.72503209678849E-6
initial amount: NaN
in compartment: COPASI2
name: eIF4A
type: Species

COPASI121
boundary condition: false
constant: false
initial amount: NaN
has only substance units: false
initial concentration: 0.0
type: Species
has part: CHEBI:15996
name: 80S_aa-tRNA_eEF2_GTP_13
in compartment: COPASI2
has part: P32324
has part: CHEBI:2651

http://identifiers.org/biomodels.db/BIOMD0000000457#_44cad8ae_df57_4fad_8a36_4cdfe7fa1858
stoichiometry: 1.0
species: COPASI144
type: SpeciesReference

COPASI68
has only substance units: false
in compartment: COPASI2
has part: CHEBI:17843
boundary condition: false
initial concentration: 0.0
name: 80S_tRNA_4
has part: GO:0022626
type: Species
constant: false
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000457#_554e214d_fb09_466a_b3af_431461894ce7
stoichiometry: 1.0
species: COPASI162
type: SpeciesReference

COPASI29
type: Species
has part: P10081
has part: P39936
boundary condition: false
name: eIF4E_eIF4G_mRNA_Pab1_eIF4A_eIF4B
has part: P39935
constant: false
has part: CHEBI:33699
initial concentration: 0.0
has part: P34167
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COPASI122
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COPASI69
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COPASI28
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initial amount: NaN
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COPASI62
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COPASI23
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initial amount: NaN
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COPASI61
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COPASI63
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COPASI22
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initial concentration: 7.16464328895E-7
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initial amount: NaN
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stoichiometry: 1.0
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COPASI64
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species: COPASI42
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COPASI25
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COPASI159
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COPASI65
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species: COPASI94
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COPASI24
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COPASI109
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COPASI10
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initial amount: NaN
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COPASI301
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COPASI253
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stoichiometry: 1.0
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COPASI11
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COPASI199
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COPASI302
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COPASI149
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COPASI252
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COPASI303
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value: 14200.8
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COPASI148
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COPASI107
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COPASI12
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COPASI255
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COPASI304
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COPASI147
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COPASI108
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COPASI13
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boundary condition: false
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initial concentration: 1.53979674865818E-6
initial amount: NaN
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COPASI254
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COPASI14
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stoichiometry: 1.0
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COPASI305
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stoichiometry: 1.0
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COPASI306
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stoichiometry: 1.0
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COPASI15
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initial concentration: 7.69898374329091E-6
initial amount: NaN
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stoichiometry: 1.0
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stoichiometry: 1.0
species: COPASI122
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COPASI16
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initial concentration: 2.30969512298727E-6
initial amount: NaN
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stoichiometry: 1.0
species: COPASI45
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COPASI307
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type: Reaction
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stoichiometry: 1.0
species: COPASI130
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COPASI251
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reversible: false
type: Reaction
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stoichiometry: 1.0
species: COPASI118
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COPASI17
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initial amount: NaN
type: Species
initial concentration: 0.0
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boundary condition: false
name: 40S_eIF1A
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in compartment: COPASI2

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stoichiometry: 1.0
species: COPASI45
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stoichiometry: 1.0
species: COPASI76
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COPASI308
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reversible: false
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type: Reaction
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COPASI250
type: Reaction
is part of: GO:0002182
reversible: true
name: reaction22_9
fast: false

COPASI101
initial amount: NaN
boundary condition: false
initial concentration: 0.0
name: 80S_aa-tRNA_eEF1A_GTP_10
type: Species
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has only substance units: false
has part: GO:0022626
has part: P02994
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constant: false

COPASI192
reversible: true
type: Reaction
fast: false
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stoichiometry: 1.0
species: COPASI35
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stoichiometry: 1.0
species: COPASI109
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value: 43714.4
name: k2
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stoichiometry: 1.0
species: COPASI12
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value: 1170250.0
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_078f9691_7464_4819_a21e_672b5109b3a5
stoichiometry: 1.0
species: COPASI8
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stoichiometry: 1.0
species: COPASI57
type: SpeciesReference

COPASI102
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name: 80S_aa-tRNA_10
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boundary condition: false
initial concentration: 0.0
constant: false
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initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_1986bac1_7ef3_4b5f_b171_7ea269e06c60
stoichiometry: 1.0
species: COPASI168
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI103
type: SpeciesReference

COPASI191
type: Reaction
name: reaction11
reversible: true
fast: false
is part of: GO:0002183

http://identifiers.org/biomodels.db/BIOMD0000000457#b228a4d0_dcce_4736_ae5f_d1eaade3f959
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

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value: 57.1854
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_03e83bce_b983_4458_b679_d9ca2334d11e
stoichiometry: 1.0
species: COPASI132
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI50
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

COPASI194
type: Reaction
name: reaction14
fast: false
is part of: GO:0002183
reversible: false

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stoichiometry: 1.0
species: COPASI127
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI148
type: SpeciesReference

COPASI100
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_10
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#bfd99688_4819_4579_80ba_dc1db3117e08
value: 4.33541E7
name: k2
type: LocalParameter

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stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI193
type: Reaction
is part of: GO:0002183
name: reaction13
fast: false
reversible: true

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stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI93
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI157
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI93
type: SpeciesReference

COPASI196
name: reaction16
fast: false
type: Reaction
is part of: GO:0002183
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000457#d0d731d1_d56f_4ee9_a916_cf804f641123
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

COPASI105
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has part: GO:0022626
has only substance units: false
type: Species
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name: 80S_tRNA_eEF3_GTP_10
boundary condition: false
initial concentration: 0.0
constant: false
in compartment: COPASI2
has part: CHEBI:15996
initial amount: NaN

COPASI195
type: Reaction
name: reaction15
fast: false
is part of: GO:0002183
reversible: true

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stoichiometry: 1.0
species: COPASI52
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

COPASI106
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_11
type: Species

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stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI61
type: SpeciesReference

COPASI60
name: 80S_aa-tRNA_3
constant: false
in compartment: COPASI2
has only substance units: false
boundary condition: false
has part: CHEBI:2651
has part: GO:0022626
initial concentration: 0.0
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_7e136a23_9d0b_4c00_a227_91e4f00a7c93
value: 1.60265E8
name: k1
type: LocalParameter

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stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI76
type: SpeciesReference

COPASI198
type: Reaction
is part of: GO:0002183
name: reaction18
fast: false
reversible: false

COPASI103
in compartment: COPASI2
boundary condition: false
initial concentration: 0.0
name: 80S_aa-tRNA_eEF2_GTP_10
has part: CHEBI:15996
has part: P32324
has only substance units: false
constant: false
has part: CHEBI:2651
initial amount: NaN
type: Species

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stoichiometry: 1.0
species: COPASI126
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

COPASI300
reversible: true
is part of: GO:0002182
type: Reaction
name: reaction25_17
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#f04b68ac_8b0b_4f04_8af9_eca0c0c3d7f9
stoichiometry: 1.0
species: COPASI85
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI131
type: SpeciesReference

COPASI197
name: reaction17
fast: false
is part of: GO:0002183
reversible: true
type: Reaction

COPASI104
has part: GO:0022626
in compartment: COPASI2
has only substance units: false
constant: false
has part: CHEBI:17843
initial amount: NaN
boundary condition: false
type: Species
initial concentration: 0.0
name: 80S_tRNA_10

http://identifiers.org/biomodels.db/BIOMD0000000457#_4bd2f60d_2705_4c7b_bb63_e0503cb52c25
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI74
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

COPASI5
initial concentration: 0.0
type: Species
constant: false
in compartment: COPASI2
has part: P20459
has part: P32481
has part: P09064
has part: P14741
has part: CHEBI:17552
name: eIF2_GDP_eIF2B
has part: P12754
has only substance units: false
initial amount: NaN
has part: P09032
boundary condition: false
has part: P32502
has part: P32501

COPASI294
reversible: true
is part of: GO:0002182
fast: false
name: reaction25_16
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_6abe318c_1655_4751_8bfc_e9e3d2e8f27e
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

COPASI201
reversible: true
name: reaction21
fast: false
is part of: GO:0002182
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_3b13c9e0_5148_4d4b_9a03_d6ee93f407cd
stoichiometry: 1.0
species: COPASI49
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

COPASI53
initial concentration: 0.0
in compartment: COPASI2
has part: CHEBI:2651
has only substance units: false
type: Species
has part: P02994
name: 80S_aa-tRNA_eEF1A_GTP_2
initial amount: NaN
constant: false
boundary condition: false
has part: GO:0022626
has part: CHEBI:15996

http://identifiers.org/biomodels.db/BIOMD0000000457#_27d9188f_e4cc_4dfa_be30_6130e0a82bc5
value: 307831.0
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_3e7c9b01_fb25_4c74_a5b6_0e116ff1a899
stoichiometry: 1.0
species: COPASI152
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI145
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stoichiometry: 1.0
species: COPASI73
type: SpeciesReference

COPASI4
initial concentration: 2.26917415591732E-7
name: eIF2B
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type: Species
constant: false
has part: P09032
boundary condition: false
has part: P32502
has part: P32501
has part: P14741
has only substance units: false
in compartment: COPASI2
initial amount: NaN

COPASI295
is part of: GO:0002182
name: reaction26_16
reversible: false
fast: false
type: Reaction

COPASI200
fast: false
type: Reaction
name: reaction20
is part of: GO:0002182
reversible: true

ORG:
  orgname: The University of Manchester
n:
  given: Juergen
  family: Pahle

COPASI52
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_2
type: Species

COPASI50
has only substance units: false
constant: false
in compartment: COPASI2
has part: CHEBI:2651
initial concentration: 0.0
name: 80S_aa-tRNA_1
type: Species
has part: GO:0022626
initial amount: NaN
boundary condition: false

COPASI292
reversible: true
fast: false
is part of: GO:0002182
name: reaction22_16
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_47ad4240_3fff_48ef_9cdd_a5df593929b4
stoichiometry: 1.0
species: COPASI150
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI145
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI143
type: SpeciesReference

COPASI203
reversible: true
fast: false
is part of: GO:0002182
name: reaction27
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#b57bc5c4_ffa3_4325_b427_f406e786bd50
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI129
type: SpeciesReference

COPASI7
is: CHEBI:29173
constant: true
boundary condition: true
has only substance units: false
initial concentration: 2.59334189247694E-5
initial amount: NaN
in compartment: COPASI2
name: Met-tRNA
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_0dbe57c8_8ef7_4ba2_a853_f9cbf3d56457
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI92
type: SpeciesReference

COPASI51
initial concentration: 0.0
in compartment: COPASI2
has only substance units: false
has part: CHEBI:2651
name: 80S_aa-tRNA_eEF2_GTP_1
type: Species
has part: P32324
boundary condition: false
initial amount: NaN
has part: CHEBI:15996
constant: false

COPASI293
reversible: false
type: Reaction
fast: false
is part of: GO:0002182
name: reaction23_16

COPASI202
type: Reaction
fast: false
is part of: GO:0002182
reversible: true
name: reaction24

http://identifiers.org/biomodels.db/BIOMD0000000457#_688651cf_e2b4_474d_b016_b3f92c715bba
stoichiometry: 1.0
species: COPASI109
type: SpeciesReference

COPASI6
name: eIF2_GTP
initial concentration: 0.0
has only substance units: false
has part: P32481
constant: false
in compartment: COPASI2
type: Species
is version of: GO:0005850
has part: P20459
boundary condition: false
has part: P09064
initial amount: NaN
has part: CHEBI:15996

COPASI290
fast: false
name: reaction28_15
is part of: GO:0002182
reversible: false
type: Reaction

COPASI57
in compartment: COPASI2
has part: CHEBI:2651
has part: P16521
has only substance units: false
initial amount: NaN
initial concentration: 0.0
has part: GO:0022626
name: 80S_tRNA_eEF3_GTP_2
has part: CHEBI:15996
type: Species
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000457#c7047992_d353_4564_9f00_4b0c045e3374
stoichiometry: 1.0
species: COPASI146
type: SpeciesReference

COPASI110
initial amount: NaN
has part: CHEBI:17843
name: 80S_tRNA_11
constant: false
initial concentration: 0.0
boundary condition: false
has part: GO:0022626
in compartment: COPASI2
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_559b79bc_e8c6_4fe8_b9e5_b1d1c929d34e
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_8480bbca_0831_480b_9f4b_9293cdfcde40
stoichiometry: 1.0
species: COPASI40
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI96
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

COPASI150
has part: CHEBI:2651
constant: false
in compartment: COPASI2
has part: GO:0022626
initial concentration: 0.0
initial amount: NaN
has only substance units: false
boundary condition: false
name: 80S_aa-tRNA_18
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#_14d4268b_d217_4204_aa9b_4a6a4365bc4c
stoichiometry: 1.0
species: COPASI150
type: SpeciesReference

COPASI291
reversible: false
name: reaction29_15
is part of: GO:0002182
fast: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_6635447b_f516_4772_97fe_7678d4d84c45
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI137
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f9f14a47_439e_475d_8c61_02c59cbfba97
value: 5.79912E7
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_9fa3cbad_77ae_4c7b_8360_5ae454255931
value: 39591.9
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_53c17c72_e773_4ff5_84d2_cdcf907423c9
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

COPASI56
has only substance units: false
in compartment: COPASI2
initial amount: NaN
has part: GO:0022626
name: 80S_tRNA_2
initial concentration: 0.0
type: Species
has part: CHEBI:17843
constant: false
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_64c5e76c_582a_4d90_9b83_d8d9314fac8e
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_9bb09e30_c150_41c4_9f50_19c7a51f71aa
stoichiometry: 1.0
species: COPASI68
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_8a1fef35_0ae8_491f_bcaa_bfe5d38406c6
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#dfb6713f_6c49_48b4_9b47_e576f6666f90
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_1dde80af_b94f_43de_8afd_51c3d4db1e12
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

COPASI3
is version of: GO:0005850
has part: P32481
has part: P20459
has part: P09064
constant: false
type: Species
has only substance units: false
name: eIF2_GDP
boundary condition: false
has part: CHEBI:17552
initial concentration: 1.17510804502861E-6
initial amount: NaN
in compartment: COPASI2

COPASI55
in compartment: COPASI2
constant: false
has part: P32324
has only substance units: false
has part: CHEBI:2651
initial concentration: 0.0
name: 80S_aa-tRNA_eEF2_GTP_2
initial amount: NaN
has part: CHEBI:15996
boundary condition: false
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#a093f6af_6264_4cca_8f45_6535da4607ae
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

COPASI2
is: GO:0005737
constant: true
size: 4.0E-14
spatial dimensions: 3.0
name: cytoplasm
type: Compartment

http://identifiers.org/biomodels.db/BIOMD0000000457#cf74c3d3_ad82_4e28_bd76_1fe029c595fc
stoichiometry: 1.0
species: COPASI65
type: SpeciesReference

COPASI190
fast: false
type: Reaction
is part of: GO:0002183
name: reaction10
reversible: true

COPASI54
name: 80S_aa-tRNA_2
type: Species
boundary condition: false
has only substance units: false
initial amount: NaN
initial concentration: 0.0
constant: false
in compartment: COPASI2
has part: GO:0022626
has part: CHEBI:2651

http://identifiers.org/biomodels.db/BIOMD0000000457#d749a5d6_2160_490b_8856_03ee05965365
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_9122fa32_70b7_43af_86ab_c88721243fff
stoichiometry: 1.0
species: COPASI63
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f6c9c7e4_b4ba_44c3_8576_5137c3c1fd00
value: 93.5995
name: k1
type: LocalParameter

COPASI209
reversible: false
fast: false
name: reaction23_2
is part of: GO:0002182
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_397080a0_dcec_4fd0_915c_3719df710a2e
stoichiometry: 1.0
species: COPASI82
type: SpeciesReference

COPASI153
in compartment: COPASI2
has part: GO:0022626
has only substance units: false
has part: CHEBI:15996
has part: P16521
boundary condition: false
name: 80S_tRNA_eEF3_GTP_18
initial amount: NaN
type: Species
constant: false
has part: CHEBI:2651
initial concentration: 0.0

COPASI248
type: Reaction
fast: false
reversible: false
is part of: GO:0002182
name: reaction28_8

COPASI19
is: P07260
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.24167736559617E-6
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COPASI205
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COPASI298
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COPASI157
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COPASI245
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COPASI204
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COPASI299
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value: 4.33274E7
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COPASI158
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COPASI207
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value: 533.26
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type: LocalParameter

COPASI296
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value: 6.32998
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type: LocalParameter

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stoichiometry: 1.0
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COPASI155
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name: 80S_aa-tRNA_eEF1A_GTP_19

COPASI247
fast: false
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value: 35378.1
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type: LocalParameter

COPASI206
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COPASI297
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COPASI156
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type: Species
in compartment: COPASI2
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COPASI136
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COPASI267
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COPASI90
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COPASI135
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value: 1.29513
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COPASI266
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COPASI189
is part of: GO:0002183
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stoichiometry: 1.0
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COPASI138
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initial amount: NaN

COPASI265
fast: false
is part of: GO:0002182
reversible: false
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type: Reaction

COPASI92
in compartment: COPASI2
constant: false
type: Species
has only substance units: false
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initial concentration: 0.0
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has part: CHEBI:17843
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stoichiometry: 1.0
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COPASI188
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stoichiometry: 1.0
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COPASI137
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COPASI264
type: Reaction
name: reaction25_11
fast: false
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COPASI91
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initial concentration: 0.0
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type: Species
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has only substance units: false
name: 80S_aa-tRNA_eEF2_GTP_8
in compartment: COPASI2
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initial amount: NaN

COPASI187
reversible: false
fast: false
name: reaction7
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type: Reaction

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stoichiometry: 1.0
species: COPASI152
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stoichiometry: 1.0
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COPASI95
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has part: CHEBI:15996
has only substance units: false
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name: 80S_aa-tRNA_eEF1A_GTP_9

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stoichiometry: 1.0
species: COPASI36
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value: 1.06204E9
name: k1
type: LocalParameter

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stoichiometry: 1.0
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COPASI94
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initial concentration: 0.0
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in compartment: COPASI2
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COPASI263
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is part of: GO:0002182
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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COPASI93
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has only substance units: false
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COPASI262
type: Reaction
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is part of: GO:0002182

COPASI139
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type: Species
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initial concentration: 0.0
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boundary condition: false

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stoichiometry: 1.0
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stoichiometry: 1.0
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COPASI97
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initial amount: NaN
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has only substance units: false
has part: CHEBI:2651
type: Species

COPASI261
name: reaction29_10
is part of: GO:0002182
fast: false
reversible: false
type: Reaction

BIOMD0000000457
species: COPASI65
species: COPASI9
species: COPASI31
reaction: COPASI197
species: COPASI135
species: COPASI67
species: COPASI49
reaction: COPASI232
reaction: COPASI241
reaction: COPASI295
reaction: COPASI244
reaction: COPASI253
species: COPASI110
species: COPASI146
species: COPASI119
reaction: COPASI192
reaction: COPASI230
is part of: http://identifiers.org/taxonomy/4932
reaction: COPASI205
species: COPASI30
reaction: COPASI181
species: COPASI53
species: COPASI11
species: COPASI89
species: COPASI165
species: COPASI123
species: COPASI150
parameter: COPASI170
species: COPASI55
species: COPASI37
reaction: COPASI265
reaction: COPASI256
parameter: COPASI179
reaction: COPASI303
reaction: COPASI315
species: COPASI167
reaction: COPASI268
reaction: COPASI277
species: COPASI107
species: COPASI134
compartment: COPASI2
species: COPASI39
species: COPASI118
reaction: COPASI242
reaction: COPASI296
reaction: COPASI254
species: COPASI52
reaction: COPASI310
species: COPASI10
reaction: COPASI217
reaction: COPASI229
reaction: COPASI193
species: COPASI54
species: COPASI77
reaction: COPASI291
species: COPASI7
species: COPASI133
species: COPASI147
species: COPASI38
reaction: COPASI206
species: COPASI79
species: COPASI19
reaction: COPASI289
species: COPASI117
species: COPASI158
parameter: COPASI171
reaction: COPASI201
is described by: http://identifiers.org/pubmed/23340841
reaction: COPASI266
species: COPASI40
name: Translocation with blocking (for codon number (length(mRNA)-length(Ribosome)) [1] [1]
reaction: COPASI278
species: COPASI76
species: COPASI42
species: COPASI78
reaction: COPASI261
parameter: COPASI175
species: COPASI18
reaction: COPASI311
notes: Firczuk2013 - Eukaryotic mRNA translation machinery This is a model of Saccharomyces cerevisiae mRNA translation which includes the initiation, elongation and termination phases. The model is for 20 condon mRNAs. The building of a multi-factor complex in initiation and also the different processes in elongation and termination are modelled in detail. The model takes into account that ribosomes cover more than one codon of mRNA so that the movement of ribosomes are effectively blocked by other ribosomes several codons downstream. It is assumed that 15 codons are occupied by each ribosome. This blocking effect is considered in reaction R18 in initiation and also reaction R26, the reaction where translocation of ribosomes takes place in elongation. The kinetic functions of these two reactions are based on MacDonald et al. 1968 and Heinrich & Rapaport 1980. All other kinetic functions follow mass-action kinetics. The concentrations of transfer RNA species (Met-tRNA, aa-tRNA and tRNA in the model) are kept constant, while the other species' concentrations can change in the course of the simulation. The model describes the translation of a short mRNA with 20 codons. Therefore, all reactions in the elongation cycle (R22, R23, R25, R26, R28 and R29) and the corresponding species are replicated accordingly to model the species with ribosomes bound at different positions. In summary, the model contains 165 different species and 141 reactions. The value of the 56 rate constant parameters were estimated by fitting the model against a series of experimental data consisting of modulation of the various translation factors (Figures 2, 3 and S3). Overall the parameter estimation was carried out over 212 different data points (steady states). This model is described in the article: An in vivo control map for the eukaryotic mRNA translation machinery Helena Firczuk, Shichina Kannambath, Jürgen Pahle, Amy Claydon, Robert Beynon, John Duncan, Hans Westerhoff, Pedro Mendes and John EG M…

COPASI96
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name: 80S_aa-tRNA_9
initial concentration: 0.0
in compartment: COPASI2
initial amount: NaN
has only substance units: false
constant: false
type: Species
has part: GO:0022626
boundary condition: false

COPASI260
is part of: GO:0002182
type: Reaction
name: reaction28_10
fast: false
reversible: false

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stoichiometry: 1.0
species: COPASI136
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI182
name: reaction2
fast: false
is part of: GO:0002183
type: Reaction
reversible: true

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stoichiometry: 1.0
species: COPASI107
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_27872bef_a326_4bb6_9b42_d21c40227c36
stoichiometry: 1.0
species: COPASI155
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b2779669_19c6_4d4c_bda0_c26e94c3944b
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#e6ebb286_fb37_46bc_8e92_be61ea497fd8
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_9a22f4cc_2777_46c8_bcb0_5da534b360ed
value: 5.61005E8
name: k1
type: LocalParameter

COPASI181
reversible: true
is part of: GO:0002183
name: reaction1
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_252f6160_0b6e_4107_b24f_91e560293bc0
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_031ebe99_3d8a_406b_a00f_1e5fa2a1cf7a
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_456e4d43_e0cd_4610_80d7_4da96efbbeef
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI180
constant: true
value: 2.86585731558E-20
name: mRNA_tot_Molar
type: Parameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_3f47f6a5_0adb_4143_9e92_b9eaf41b8e24
stoichiometry: 1.0
species: COPASI111
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_56305aa4_145c_45e6_813a_1f98c5032a80
stoichiometry: 1.0
species: COPASI79
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d678e851_3fcb_42af_9600_79a34af0b9e0
stoichiometry: 1.0
species: COPASI75
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#f6981b2a_8a86_4604_914f_322de687a17f
stoichiometry: 1.0
species: COPASI119
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_84893eff_45ef_40d1_a5b4_d239b2c4122b
stoichiometry: 1.0
species: COPASI159
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#ce36f429_957e_4e26_937c_5108ef656ca4
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_875fecba_ffeb_45d2_b874_05b4e55d5bff
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

COPASI186
reversible: true
type: Reaction
fast: false
is part of: GO:0002183
name: reaction6

http://identifiers.org/biomodels.db/BIOMD0000000457#_53c8fd53_ee80_46d5_be79_6cce46fdd665
stoichiometry: 1.0
species: COPASI128
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_04e7db9f_e5f6_4c15_8c30_e967732fff91
stoichiometry: 1.0
species: COPASI90
type: SpeciesReference

COPASI185
name: reaction5
fast: false
is part of: GO:0002183
reversible: true
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_4ff9c535_e6a1_4f4b_bcc1_03f87e7c3405
stoichiometry: 1.0
species: COPASI31
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_38fc6a49_6b8a_47c4_8db6_c2faeea4af26
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_7cc76701_20ec_4e97_8bde_ee6d3d534f97
stoichiometry: 1.0
species: COPASI110
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI86
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_8862ee9d_c6f8_416b_a266_2af61103e158
stoichiometry: 1.0
species: COPASI140
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_1e4982ba_f703_4ac3_a87d_3704799bc9f9
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

COPASI184
fast: false
is part of: GO:0002183
name: reaction4
type: Reaction
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000457#_1882fd49_fd76_4694_85bd_e7f26d96b80c
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_1ec76e3f_397e_4803_9e52_acb04a8b5c5c
stoichiometry: 1.0
species: COPASI105
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_7b1d96ad_c6e6_41cc_ba76_a4895d87b2ab
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#c196187f_d9e1_4cea_8854_3b370aa33781
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#c32ad234_1fb0_4909_8ba8_a03dfe648ef3
stoichiometry: 1.0
species: COPASI39
type: SpeciesReference

COPASI183
type: Reaction
is part of: GO:0002183
reversible: true
name: reaction3
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_71a723b9_9b9d_4ea8_b935_a35fe40c5e54
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_647b9485_e95e_4e15_8c7b_f9e8158bf2ee
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#a956a023_6a47_4872_8537_c08d0eb49b4f
stoichiometry: 1.0
species: COPASI135
type: SpeciesReference

COPASI215
type: Reaction
fast: false
reversible: false
is part of: GO:0002182
name: reaction23_3

COPASI214
fast: false
is part of: GO:0002182
type: Reaction
reversible: true
name: reaction22_3

http://identifiers.org/biomodels.db/BIOMD0000000457#a4e6b8e2_239c_48d9_abe8_469221ee3de4
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#e2b72adc_1991_4562_81c6_c811983fa192
value: 0.785013
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_82fce69c_59af_48f2_b4d1_572f4c9b76a8
value: 8.80234E-6
name: k2
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#f7d55cd6_21e9_4daa_bf56_40aa21b6f270
stoichiometry: 1.0
species: COPASI115
type: SpeciesReference

COPASI213
name: reaction29_2
reversible: false
type: Reaction
fast: false
is part of: GO:0002182

http://identifiers.org/biomodels.db/BIOMD0000000457#_2a085d53_cc23_4d51_9ae2_12f4615b6ba9
stoichiometry: 1.0
species: COPASI49
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#afb23213_8f5d_48e8_818d_dc610c7b69b2
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#b3aa48ee_9082_41da_8fbb_b7683683b2d1
stoichiometry: 1.0
species: COPASI67
type: SpeciesReference

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stoichiometry: 1.0
species: COPASI86
type: SpeciesReference

COPASI41
is: CHEBI:2651
constant: true
boundary condition: true
has only substance units: false
initial concentration: 5.18668391964828E-4
initial amount: NaN
in compartment: COPASI2
name: aa-tRNA
type: Species

COPASI212
fast: false
reversible: false
is part of: GO:0002182
type: Reaction
name: reaction28_2

http://identifiers.org/biomodels.db/BIOMD0000000457#d6880de2_72a6_4154_874c_ba0b80bcbbb7
stoichiometry: 1.0
species: COPASI120
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#ad4193ac_1d9b_42ef_88ec_eea92b2aa5f0
stoichiometry: 1.0
species: COPASI105
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_00e99b4c_5d87_4b66_960b_3e09ffc8eb7c
stoichiometry: 1.0
species: COPASI101
type: SpeciesReference

COPASI40
has only substance units: false
is part of: GO:0005853
name: eEF1A_GTP
initial concentration: 0.0
in compartment: COPASI2
initial amount: NaN
type: Species
constant: false
has part: P02994
has part: CHEBI:15996
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_646421f6_9b45_4fee_8d10_24a1edd04df6
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d7fdca93_7019_409e_b586_4e70a4fc8205
value: 31.1969
name: k2
type: LocalParameter

COPASI211
is part of: GO:0002182
fast: false
reversible: false
name: reaction26_2
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_7a9d473d_ec8c_4b2f_b63d_4af5e5e197a6
stoichiometry: 1.0
species: COPASI59
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#a71c0a99_012e_4e0c_80f0_e04c0445f5a9
stoichiometry: 1.0
species: COPASI59
type: SpeciesReference

COPASI43
type: Species
initial amount: NaN
name: eEF2_GDP
constant: false
boundary condition: false
has part: CHEBI:17552
initial concentration: 5.6729353897933E-6
has part: P32324
in compartment: COPASI2
has only substance units: false

COPASI210
is part of: GO:0002182
type: Reaction
name: reaction25_2
reversible: true
fast: false

COPASI42
name: aa-tRNA_eEF1A_GTP
boundary condition: false
has only substance units: false
type: Species
initial amount: NaN
constant: false
initial concentration: 0.0
in compartment: COPASI2
has part: P02994
has part: CHEBI:15996
has part: CHEBI:2651

http://identifiers.org/biomodels.db/BIOMD0000000457#_3dda3acb_a60c_4c76_927b_81c4e8d97d37
stoichiometry: 1.0
species: COPASI89
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_8b19284a_4a80_42e3_bd63_2595efdfaf96
stoichiometry: 1.0
species: COPASI135
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_9654aec4_956d_4158_b518_8d385fa0246b
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#a0f62f03_48bd_4c44_8fa5_01ae13f3ab8b
stoichiometry: 1.0
species: COPASI34
type: SpeciesReference

COPASI45
boundary condition: false
initial concentration: 4.45730637769471E-6
name: eEF3_GDP
has part: CHEBI:17552
type: Species
constant: false
in compartment: COPASI2
has part: P16521
has only substance units: false
initial amount: NaN

http://identifiers.org/biomodels.db/BIOMD0000000457#_58b305bf_08a1_4eed_81e1_58be33a2ce52
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

COPASI44
initial amount: NaN
in compartment: COPASI2
has part: P32324
has part: CHEBI:15996
initial concentration: 0.0
name: eEF2_GTP
type: Species
constant: false
boundary condition: false
has only substance units: false

COPASI47
is: CHEBI:17843
constant: true
boundary condition: true
has only substance units: false
initial concentration: 2.59333683546025E-4
initial amount: NaN
in compartment: COPASI2
name: tRNA
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#de7b0c0b_6558_4bd2_af79_c423336963bc
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#eb279cc7_8b90_47eb_b29d_480076b1ff47
stoichiometry: 1.0
species: COPASI47
type: SpeciesReference

COPASI86
type: Species
has part: CHEBI:17843
name: 80S_tRNA_7
has part: GO:0022626
boundary condition: false
has only substance units: false
initial amount: NaN
initial concentration: 0.0
in compartment: COPASI2
constant: false

COPASI46
constant: false
has only substance units: false
has part: P16521
has part: CHEBI:15996
initial amount: NaN
name: eEF3_GTP
in compartment: COPASI2
boundary condition: false
type: Species
initial concentration: 0.0

http://identifiers.org/biomodels.db/BIOMD0000000457#cab3ade4_73ec_4a5c_9660_86d5ad2284a0
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_15d2f02a_9cea_461a_bd1e_36205bc345cc
stoichiometry: 1.0
species: COPASI100
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_5d89a8b4_b0ae_4ee0_bf7f_09f27edd56cc
stoichiometry: 1.0
species: COPASI130
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d84fd007_199f_4cf5_bf78_91fed67d3ba9
stoichiometry: 1.0
species: COPASI43
type: SpeciesReference

COPASI140
has only substance units: false
initial concentration: 0.0
initial amount: NaN
has part: GO:0022626
name: 80S_tRNA_16
boundary condition: false
type: Species
in compartment: COPASI2
constant: false
has part: CHEBI:17843

COPASI87
initial concentration: 0.0
in compartment: COPASI2
has part: GO:0022626
name: 80S_tRNA_eEF3_GTP_7
has only substance units: false
initial amount: NaN
constant: false
has part: CHEBI:2651
type: Species
has part: P16521
has part: CHEBI:15996
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000457#_8989ede4_6fed_49ec_b2d1_e6747b4ca5bc
stoichiometry: 1.0
species: COPASI32
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_06e5006a_2c45_4ee1_b20a_79334a71faab
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

COPASI49
has part: GO:0022626
constant: false
initial concentration: 0.0
in compartment: COPASI2
has only substance units: false
boundary condition: false
has part: CHEBI:2651
name: 80S_aa-tRNA_eEF1A_GTP_1
has part: P02994
has part: CHEBI:15996
initial amount: NaN
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#acdeccc6_46f0_4683_9ef1_2d45c8db8de0
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

COPASI88
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_8
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000457#f385f16d_e43e_47dc_8b47_a7d075924f88
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI141
initial concentration: 0.0
in compartment: COPASI2
has part: GO:0022626
has part: P16521
boundary condition: false
has part: CHEBI:15996
initial amount: NaN
type: Species
name: 80S_tRNA_eEF3_GTP_16
constant: false
has part: CHEBI:2651
has only substance units: false

http://identifiers.org/biomodels.db/BIOMD0000000457#d19c2f2e_0744_44d3_8f40_1bca27315c00
stoichiometry: 1.0
species: COPASI167
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#cbd05362_3ac2_4d6f_bae1_fd142c5351ba
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI48
name: 80S_1
in compartment: COPASI2
initial amount: NaN
type: Species
boundary condition: false
has part: GO:0022626
constant: false
is: GO:0070992
has only substance units: false
initial concentration: 0.0

COPASI89
initial concentration: 0.0
type: Species
has only substance units: false
name: 80S_aa-tRNA_eEF1A_GTP_8
has part: CHEBI:2651
initial amount: NaN
has part: P02994
has part: CHEBI:15996
boundary condition: false
in compartment: COPASI2
has part: GO:0022626
constant: false

COPASI142
has part: GO:0022626
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: COPASI2
name: 80S_17
type: Species

COPASI219
fast: false
name: reaction29_3
is part of: GO:0002182
reversible: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_296c9cf9_f8ab_4374_858d_e563557fe099
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_9f4b0ebe_6c5a_4524_8076_f9a358826697
value: 1.53068E8
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#_3d018fd6_f529_4577_9537_bf5aba7eb2b0
stoichiometry: 1.0
species: COPASI95
type: SpeciesReference

COPASI258
is part of: GO:0002182
type: Reaction
fast: false
reversible: true
name: reaction25_10

http://identifiers.org/biomodels.db/BIOMD0000000457#d0846dae_b002_4300_a0f8_381d9fc4bec2
stoichiometry: 1.0
species: COPASI155
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_48e3fc48_97bb_4a9e_9f4d_4f4d9477030e
stoichiometry: 1.0
species: COPASI97
type: SpeciesReference

COPASI143
initial amount: NaN
has only substance units: false
has part: GO:0022626
type: Species
has part: CHEBI:2651
initial concentration: 0.0
has part: CHEBI:15996
in compartment: COPASI2
has part: P02994
boundary condition: false
constant: false
name: 80S_aa-tRNA_eEF1A_GTP_17

http://identifiers.org/biomodels.db/BIOMD0000000457#_95c783ce_5d81_40da_bde5_e3d9c8112f9e
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_625e1e80_779e_4ca6_a7bf_9c47ce79f276
stoichiometry: 1.0
species: COPASI66
type: SpeciesReference

COPASI218
is part of: GO:0002182
reversible: false
fast: false
name: reaction28_3
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#ff2bdfc6_c7c8_4f5a_921e_a84b89ca02d7
stoichiometry: 1.0
species: COPASI60
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_56d0905d_fbd7_4144_ab6a_baccdd18f431
stoichiometry: 1.0
species: COPASI44
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#d0a8882d_e331_40e2_b9bc_4b2a7d126fd0
value: 1.3072E13
name: k
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#c94b91d6_abf9_406c_a09e_c6bc247d1af9
stoichiometry: 1.0
species: COPASI62
type: SpeciesReference

COPASI144
constant: false
name: 80S_aa-tRNA_17
has part: CHEBI:2651
initial concentration: 0.0
in compartment: COPASI2
boundary condition: false
initial amount: NaN
has only substance units: false
has part: GO:0022626
type: Species

COPASI259
name: reaction26_10
is part of: GO:0002182
reversible: false
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000457#b1c939bb_3e4f_4508_8736_b0f933fc0f14
stoichiometry: 1.0
species: COPASI37
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_4ff1dd2a_13f8_4e48_915a_3841ca766c4d
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000457#_190041b1_cea8_482d_906d_feb45377e74a
stoichiometry: 1.0
species: COPASI147
type: SpeciesReference

COPASI217
fast: false
reversible: false
is part of: GO:0002182
type: Reaction
name: reaction26_3

COPASI256
is part of: GO:0002182
type: Reaction
fast: false
name: reaction22_10
reversible: true

http://identifiers.org/biomodels.db/BIOMD0000000457#c4ac7ae6_d00a_4033_b812_e39fd46effe4
stoichiometry: 1.0
species: COPASI45
type: SpeciesReference

COPASI145
boundary condition: false
initial concentration: 0.0
name: 80S_aa-tRNA_eEF2_GTP_17
has part: P32324
type: Species
constant: false
has part: CHEBI:2651
has only substance units: false
has part: CHEBI:15996
initial amount: NaN
in compartment: COPASI2

http://identifiers.org/biomodels.db/BIOMD0000000457#eb048d6d_7456_41ac_ac7f_2270a94252a3
stoichiometry: 1.0
species: COPASI114
type: SpeciesReference

COPASI216
name: reaction25_3
is part of: GO:0002182
fast: false
reversible: true
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000457#_78239b57_a20b_4ad9_91f3_8cc5169c1ba9
stoichiometry: 1.0
species: COPASI42
type: SpeciesReference

COPASI257
is part of: GO:0002182
fast: false
reversible: false
type: Reaction
name: reaction23_10

COPASI146
has part: CHEBI:17843
in compartment: COPASI2
type: Species
boundary condition: false
constant: false
has part: GO:0022626
has only substance units: false
initial concentration: 0.0
initial amount: NaN
name: 80S_tRNA_17

http://identifiers.org/biomodels.db/BIOMD0000000457#b62e9558_28fd_4d69_9a6c_9b278258af25
value: 1.6E9
name: k1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000457#f634be6e_ed89_4b18_8fe7_00b6bcc7ed9f
stoichiometry: 1.0
species: COPASI46
type: SpeciesReference

given: Shichina
family: Kannambath

ORG:
  orgname: The University of Manchester