557185
value: 1.0E8
name: k1
type: LocalParameter

557199
value: 1.0
name: k2
type: LocalParameter

COPASI33
constant: true
value: 2.25E-7
name: kappa
type: Parameter

COPASI23
constant: false
initial concentration: 2.0E-5
is: SBO:0000245
name: Z
has only substance units: false
type: Species
initial amount: NaN
is: P0A9H9
boundary condition: false
in compartment: COPASI2

COPASI52
kinetic law: 382313
is: SBO:0000177
reversible: true
reactant: 382277
product: 382301
reactant: 382289
fast: false
type: Reaction
name: T+ni<->Tni
is version of: GO:0016151

557222
value: 0.01
name: k1
type: LocalParameter

COPASI71
reactant: 383203
kinetic law: 383227
name: MYpYp+Yp<->MYpYpYp
is: SBO:0000177
fast: false
reactant: 383191
is version of: GO:0006461
type: Reaction
product: 383215
reversible: true

COPASI13
name: Tasp_A
constant: false
boundary condition: false
has part: P07363
is: SBO:0000253
initial amount: NaN
in compartment: COPASI2
has part: P07017
initial concentration: 0.0
has part: CHEBI:35391
has only substance units: false
type: Species

COPASI62
product: 382783
reactant: 382759
type: Reaction
kinetic law: 382795
reactant: 382771
reversible: true
is: SBO:0000177
name: Tasp_A+W<->Tasp_WA
is version of: GO:0006461
fast: false

557212
value: 10000.0
name: k1
type: LocalParameter

COPASI43
kinetic law: 381868
is: SBO:0000216
product: 381844
fast: false
reversible: false
name: Tni_WA+A->Tni_WA+Ap
is version of: http://identifiers.org/ec-code/2.7.11.1
type: Reaction
modifier: 381856
reactant: 381832
is version of: GO:0006468

383191
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

381832
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

ORG:
  orgname: EMBL-EBI
n:
  given: Nicolas
  family: Le Novère

COPASI8
is: P0A964
initial concentration: 2.89E-6
is: SBO:0000245
has only substance units: false
type: Species
boundary condition: false
initial amount: NaN
constant: false
name: W
in compartment: COPASI2

COPASI53
is: SBO:0000177
type: Reaction
reactant: 382325
fast: false
reactant: 382338
kinetic law: 382362
reversible: true
name: T+W<->TW
product: 382350
is version of: GO:0006461

382289
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

381796
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

557186
value: 200000.0
name: k1
type: LocalParameter

COPASI34
constant: true
value: 0.1
name: ka
type: Parameter

382675
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

557223
value: 1.0
name: k2
type: LocalParameter

COPASI24
type: Species
has only substance units: false
boundary condition: false
in compartment: COPASI2
is version of: P0AE67
constant: false
initial concentration: 9.9E-6
is: SBO:0000245
initial amount: NaN
name: Y

557213
value: 1.0
name: k2
type: LocalParameter

COPASI14
is: SBO:0000253
initial concentration: 0.0
initial amount: NaN
has part: CHEBI:49786
has part: P07017
name: Tni_A
boundary condition: false
has part: P07363
has only substance units: false
in compartment: COPASI2
type: Species
constant: false

COPASI63
kinetic law: 382843
type: Reaction
reactant: 382819
is version of: GO:0006461
fast: false
product: 382831
reversible: true
is: SBO:0000177
reactant: 382807
name: Tasp+WA<->Tasp_WA

COPASI70
product: 383167
fast: false
name: MYp+Yp<->MYpYp
reactant: 383155
kinetic law: 383179
type: Reaction
is version of: GO:0006461
is: SBO:0000177
reactant: 383143
reversible: true

COPASI44
reactant: 381880
is: SBO:0000330
product: 381904
fast: false
is version of: http://identifiers.org/ec-code/3.1.3.16
reversible: false
product: 381916
reactant: 381892
kinetic law: 381929
type: Reaction
name: Tasp_WA+Yp->Tasp_WA+Y
is version of: GO:0006470

382374
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

383396
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

383215
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

557233
value: 1000000.0
name: k1
type: LocalParameter

COPASI64
reactant: 382855
name: Tni+W<->Tni_W
product: 382879
is: SBO:0000177
type: Reaction
reversible: true
is version of: GO:0006461
kinetic law: 382891
reactant: 382867
fast: false

382193
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

COPASI54
name: T+A<->TA
reversible: true
is version of: GO:0006461
fast: false
reactant: 382374
kinetic law: 382410
is: SBO:0000177
type: Reaction
product: 382398
reactant: 382386

382097
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

382975
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

382482
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI7
has part: P07017
in compartment: COPASI2
name: Tni
initial amount: NaN
has only substance units: false
is: SBO:0000253
initial concentration: 0.0
has part: CHEBI:49786
type: Species
constant: false
boundary condition: false

382879
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

COPASI25
has only substance units: false
is version of: P0AE67
name: Yp
initial concentration: 7.0E-9
constant: false
boundary condition: false
initial amount: NaN
in compartment: COPASI2
has property: MOD:00696
type: Species

383239
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

COPASI50
kinetic law: 382217
is version of: GO:0006470
name: Bp->B
is version of: http://identifiers.org/ec-code/3.1.3.16
reactant: 382193
fast: false
reversible: false
is: SBO:0000330
product: 382205
type: Reaction

557224
value: 0.4
name: k1
type: LocalParameter

557187
value: 0.0
name: kcat
type: LocalParameter

COPASI31
is: SBO:0000247
initial concentration: 0.1
type: Species
boundary condition: true
is: CHEBI:15422
in compartment: COPASI2
constant: true
has only substance units: false
name: ATP
initial amount: NaN

COPASI45
is version of: GO:0006468
product: 381977
kinetic law: 381989
is: SBO:0000216
reactant: 381953
type: Reaction
fast: false
reactant: 381941
product: 381965
reversible: false
is version of: http://identifiers.org/ec-code/2.7.11.1
name: Ap+Y->A+Yp

COPASI11
name: Tni_W
has only substance units: false
is: SBO:0000253
initial amount: NaN
type: Species
boundary condition: false
initial concentration: 0.0
in compartment: COPASI2
has part: CHEBI:49786
constant: false
has part: P0A964
has part: P07017

557197
value: 1.0
name: k2
type: LocalParameter

557210
value: 100000.0
name: k1
type: LocalParameter

382711
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

COPASI73
is: SBO:0000177
fast: false
type: Reaction
reactant: 383299
reversible: true
kinetic law: 383323
is version of: GO:0070335
product: 383311
name: TA + asp <-> Tasp_A
reactant: 383287

COPASI65
is version of: GO:0006461
reactant: 382915
is: SBO:0000177
type: Reaction
fast: false
name: Tni+A<->Tni_A
reversible: true
product: 382927
kinetic law: 382939
reactant: 382903

382277
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

381784
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

382639
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

382422
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

COPASI30
initial concentration: 2.31E-9
name: MYpYpYpYp
boundary condition: false
type: Species
has part: P06974
has only substance units: false
initial amount: NaN
in compartment: COPASI2
constant: false
is: SBO:0000253
has part: P0AE67

COPASI6
type: Species
in compartment: COPASI2
name: Tasp
constant: false
initial concentration: 0.0
has part: P07017
has part: CHEBI:35391
has only substance units: false
initial amount: NaN
is: SBO:0000253
boundary condition: false

381844
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

383299
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

COPASI26
type: Species
boundary condition: false
has only substance units: false
initial concentration: 6.24E-9
in compartment: COPASI2
constant: false
is: SBO:0000245
initial amount: NaN
name: M
is: P06974

COPASI51
fast: false
reactant: 382241
is: SBO:0000177
kinetic law: 382265
reversible: true
is version of: GO:0070335
name: T+asp<->Tasp
product: 382253
reactant: 382229
type: Reaction

382783
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

COPASI32
constant: true
value: 0.14
name: alpha
type: Parameter

557225
value: 1.0
name: k2
type: LocalParameter

383384
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

557198
value: 100000.0
name: k1
type: LocalParameter

382687
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

COPASI12
in compartment: COPASI2
initial concentration: 4.44E-7
is: SBO:0000253
initial amount: NaN
type: Species
name: TA
constant: false
has part: P07017
has part: P07363
has only substance units: false
boundary condition: false

COPASI46
is version of: GO:0006468
kinetic law: 382025
name: Y ->Yp
reversible: false
product: 382013
is: SBO:0000216
type: Reaction
fast: false
is version of: http://identifiers.org/ec-code/2.7.11.1
reactant: 382001

COPASI72
kinetic law: 383275
reactant: 383251
type: Reaction
reactant: 383239
reversible: true
fast: false
name: MYpYpYp+Yp<->MYpYpYpYp
product: 383263
is version of: GO:0006461
is: SBO:0000177

557211
value: 1.0
name: k2
type: LocalParameter

COPASI66
name: Tni_W+A<->Tni_WA
product: 382975
is: SBO:0000177
reactant: 382951
type: Reaction
kinetic law: 382987
reversible: true
fast: false
reactant: 382963
is version of: GO:0006461

382085
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

382470
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

COPASI5
constant: false
in compartment: COPASI2
has only substance units: false
is: P07017
initial amount: NaN
is: SBO:0000245
name: T
initial concentration: 3.12E-6
boundary condition: false
type: Species

382963
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

383047
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

383456
persistant: true
initial value: true
type: Trigger

557189
value: 0.037
name: k1
type: LocalParameter

COPASI17
type: Species
in compartment: COPASI2
has part: P07363
name: Tasp_WA
initial concentration: 0.0
boundary condition: false
is: SBO:0000253
has part: P07017
has part: P0A964
constant: false
has part: CHEBI:35391
has only substance units: false
initial amount: NaN

382627
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

COPASI27
constant: false
has only substance units: false
initial amount: NaN
has part: P06974
has part: P0AE67
is: SBO:0000253
initial concentration: 7.77E-10
in compartment: COPASI2
type: Species
boundary condition: false
name: MYp

382723
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI4
initial concentration: 0.0
in compartment: COPASI2
name: ni
is: SBO:0000247
type: Species
has only substance units: false
constant: true
boundary condition: true
is: CHEBI:49786
initial amount: NaN

COPASI57
is: SBO:0000177
name: TA+W<->TWA
reversible: true
reactant: 382531
is version of: GO:0006461
kinetic law: 382555
fast: false
product: 382543
reactant: 382519
type: Reaction

557236
value: 1.0
name: k2
type: LocalParameter

COPASI67
product: 383023
fast: false
name: Tni_A+W<->Tni_WA
reactant: 383011
type: Reaction
is version of: GO:0006461
reactant: 382999
reversible: true
kinetic law: 383035
is: SBO:0000177

382495
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

COPASI28
name: MYpYp
in compartment: COPASI2
boundary condition: false
type: Species
initial amount: NaN
initial concentration: 2.99E-10
is: SBO:0000253
has part: P06974
has part: P0AE67
constant: false
has only substance units: false

BIOMD0000000404
reaction: COPASI59
reaction: COPASI74
reaction: COPASI42
name: Autophosphorylation
species: COPASI31
reaction: COPASI47
is: MODEL6929313478
rule: 557279
reaction: COPASI71
species: COPASI15
function def: COPASI77
species: COPASI28
species: COPASI27
parameter: COPASI36
name: function_4_motor_r3
name: function_4_motor_r2
parameter: COPASI32
species: COPASI20
length unit: length
function def: COPASI76
reaction: COPASI63
reaction: COPASI68
occurs in: http://identifiers.org/taxonomy/562
species: COPASI6
reaction: COPASI51
species: COPASI5
reaction: COPASI56
reaction: COPASI60
reaction: COPASI65
species: COPASI3
species: COPASI11
reaction: COPASI44
function def: 557284
type: SBMLModel
reaction: COPASI53
reaction: COPASI49
species: COPASI24
species: COPASI23
reaction: COPASI73
species: COPASI17
curated: true
species: COPASI16
reaction: COPASI70
reaction: COPASI75
species: COPASI29
parameter: COPASI38
name: function_4_motor_r4
parameter: COPASI34
species: COPASI22
species: COPASI21
time units: metaid_0000322
name: ModAutophosphorylation
species: COPASI19
event: COPASI39
parameter: COPASI35
name: Bray1993_chemotaxis
species: COPASI30
function def: 557280
function def: 557281
area units: 498119
species: COPASI8
species: COPASI7
reaction: COPASI58
reaction: COPASI62
reaction: COPASI67
species: COPASI13
notes: This version of the model is very close to the version described in the paper with one exception: the binding of aspartate to the various receptor complexes, as well as the formation of the different complexes are modeled using chemical kinetics (mass action law), rather than instant equilibrium. The qualitative behaviour of the model is unchanged. Note that in order to quantitatively replicate the figure 8b, and in particular to have a basal bias of 0.7, we have to change the rate constant of the aspartate-triggered dephosphorylation of CheY from 59000 to 70000. The peaks have then slightly different values. This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2012 The BioModels.net Team. For more information see the terms of use . To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
species: COPASI12
reaction: COPASI41
reaction: COPASI46
reaction: COPASI50
reaction: COPASI55
reaction: COPASI64
species: COPASI26
species: COPASI25
species: COPASI9
reaction: COPASI43
reaction: COPASI48
compartment: COPASI2
species: COPASI18

383011
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

W3 CDTF: Mon Nov 03 11:29:04 GMT 2008

COPASI3
constant: false
name: asp
is: CHEBI:35391
initial amount: NaN
in compartment: COPASI2
is: SBO:0000247
has only substance units: false
type: Species
initial concentration: 0.0
boundary condition: true

382915
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

382999
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

382567
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

COPASI18
has part: P07017
name: Tni_WA
constant: false
in compartment: COPASI2
has part: P07363
has only substance units: false
initial concentration: 0.0
boundary condition: false
has part: CHEBI:49786
has part: P0A964
initial amount: NaN
type: Species
is: SBO:0000253

COPASI58
reactant: 382567
name: T+WA<->TWA
product: 382591
reactant: 382579
is version of: GO:0006461
type: Reaction
kinetic law: 382603
is: SBO:0000177
fast: false
reversible: true

COPASI68
is version of: GO:0006461
fast: false
reactant: 383047
type: Reaction
reversible: true
is: SBO:0000177
product: 383071
reactant: 383059
kinetic law: 383083
name: Tni+WA<->Tni_WA

383311
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

383287
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

382350
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

557237
value: 1000000.0
name: k1
type: LocalParameter

382615
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

382253
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

381760
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

COPASI29
type: Species
initial amount: NaN
in compartment: COPASI2
boundary condition: false
is: SBO:0000253
has part: P06974
constant: false
name: MYpYpYp
initial concentration: 3.78E-10
has only substance units: false
has part: P0AE67

382591
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

557220
value: 0.1
name: k1
type: LocalParameter

COPASI15
constant: false
has part: P0A964
has only substance units: false
initial amount: NaN
initial concentration: 6.78E-7
is: SBO:0000253
in compartment: COPASI2
has part: P07363
boundary condition: false
type: Species
name: WA

COPASI2
is version of: GO:0005623
is: SBO:0000290
constant: true
size: 1.41E-15
spatial dimensions: 3.0
name: cell
type: Compartment

COPASI55
type: Reaction
product: 382446
is version of: GO:0006461
reactant: 382422
fast: false
kinetic law: 382458
name: W+A<->WA
reactant: 382434
reversible: true
is: SBO:0000177

COPASI40
event assignment: 383469
trigger: 383456
use values from trigger time: true
name: Remove ASP
type: Event

557234
value: 1.0
name: k2
type: LocalParameter

382735
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

COPASI69
type: Reaction
reversible: true
is: SBO:0000177
reactant: 383095
name: M+Yp<->MYp
product: 383119
kinetic law: 383131
is version of: GO:0006461
fast: false
reactant: 383107

COPASI42
is version of: http://identifiers.org/ec-code/2.7.11.1
fast: false
is version of: GO:0006468
is: SBO:0000216
reversible: false
product: 381796
name: TWA+A->TWA+Ap
type: Reaction
modifier: 381808
kinetic law: 381820
reactant: 381784

382927
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

COPASI16
is: SBO:0000253
has part: P0A964
has part: P07017
type: Species
initial concentration: 8.47E-7
in compartment: COPASI2
constant: false
has part: P07363
has only substance units: false
boundary condition: false
name: TWA
initial amount: NaN

381880
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

383203
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

557221
value: 1.0
name: k2
type: LocalParameter

382579
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

382109
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

383023
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

COPASI56
product: 382495
reactant: 382482
kinetic law: 382507
reversible: true
reactant: 382470
is version of: GO:0006461
fast: false
is: SBO:0000177
type: Reaction
name: TW+A<->TWA

382663
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

557235
value: 1000000.0
name: k1
type: LocalParameter

COPASI41
name: A->Ap
reversible: false
type: Reaction
is version of: GO:0006468
fast: false
product: 381760
is: SBO:0000216
kinetic law: 381772
reactant: 381748
is version of: http://identifiers.org/ec-code/2.7.11.1

382205
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

382169
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

381916
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

557209
value: 1.0
name: k2
type: LocalParameter

557219
value: 1.0
name: k2
type: LocalParameter

383335
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

382229
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

382831
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

383263
stoichiometry: 1.0
species: COPASI30
type: SpeciesReference

557201
value: 1.0
name: k2
type: LocalParameter

382543
stoichiometry: 1.0
species: COPASI16
type: SpeciesReference

381965
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

557229
value: 1.0
name: k2
type: LocalParameter

557228
value: 0.4
name: k1
type: LocalParameter

557190
value: 500000.0
name: k1
type: LocalParameter

383119
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

557208
value: 400000.0
name: k1
type: LocalParameter

382519
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

382157
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

557218
value: 400000.0
name: k1
type: LocalParameter

557238
value: 1.0
name: k2
type: LocalParameter

382807
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

557200
value: 10000.0
name: k1
type: LocalParameter

382241
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

383071
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

557191
value: 1000000.0
name: k1
type: LocalParameter

557207
value: 1.0
name: k2
type: LocalParameter

382301
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

382001
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

557227
value: 1.0
name: k2
type: LocalParameter

383167
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

COPASI19
boundary condition: false
is: SBO:0000245
initial concentration: 3.0E-6
in compartment: COPASI2
initial amount: NaN
type: Species
name: A
constant: false
has only substance units: false
is version of: P07363

381977
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

383408
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

381892
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

382903
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

382771
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

383251
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

557226
value: 0.4
name: k1
type: LocalParameter

382819
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

382145
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

382759
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

383107
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

COPASI59
name: Tasp+W<->Tasp_W
kinetic law: 382651
type: Reaction
reactant: 382627
reversible: true
product: 382639
is version of: GO:0006461
is: SBO:0000177
fast: false
reactant: 382615

COPASI39
event assignment: 383444
trigger: 383432
use values from trigger time: true
name: Add ASP
type: Event

557206
value: 400000.0
name: k1
type: LocalParameter

382398
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

382073
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

381941
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

382855
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

COPASI10
type: Species
has part: P07017
in compartment: COPASI2
boundary condition: false
is: SBO:0000253
constant: false
has part: P0A964
has only substance units: false
name: Tasp_W
initial concentration: 0.0
initial amount: NaN
has part: CHEBI:35391

383155
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

557196
value: 1000.0
name: k1
type: LocalParameter

557205
value: 1.0
name: k2
type: LocalParameter

COPASI48
reactant: 382073
is: SBO:0000330
product: 382109
product: 382097
is version of: GO:0006470
reversible: false
fast: false
reactant: 382085
name: Yp+Z->Y+Z
type: Reaction
is version of: http://identifiers.org/ec-code/3.1.3.16
kinetic law: 382121

COPASI38
constant: true
value: 3.0E-4
name: KmATP
type: Parameter

557182
value: 75000.0
name: kcat
type: LocalParameter

557215
value: 1.0
name: k2
type: LocalParameter

COPASI20
is version of: P07363
has only substance units: false
has property: MOD:00696
is: SBO:0000245
type: Species
initial concentration: 3.48E-8
initial amount: NaN
name: Ap
in compartment: COPASI2
boundary condition: false
constant: false

382013
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

383359
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

382434
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

381904
stoichiometry: 1.0
species: COPASI17
type: SpeciesReference

383095
stoichiometry: 1.0
species: COPASI26
type: SpeciesReference

COPASI75
product: 383408
name: TWA+asp <-> Tasp_WA
is: SBO:0000177
kinetic law: 383420
reactant: 383396
fast: false
is version of: GO:0070335
reversible: true
type: Reaction
reactant: 383384

382049
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

382133
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

557204
value: 400000.0
name: k1
type: LocalParameter

557195
value: 1.0
name: k2
type: LocalParameter

COPASI74
kinetic law: 383372
is version of: GO:0070335
is: SBO:0000177
name: TW+asp <-> Tasp_W
type: Reaction
reversible: true
fast: false
reactant: 383347
product: 383359
reactant: 383335

COPASI47
reactant: 382037
is: SBO:0000330
product: 382049
kinetic law: 382061
is version of: http://identifiers.org/ec-code/3.1.3.16
type: Reaction
is version of: GO:0006470
name: Yp->Y
reversible: false
fast: false

COPASI37
constant: false
value: 0.997008973080758
name: autoPhospho
type: Parameter

557181
value: 0.001
name: kcat
type: LocalParameter

557214
value: 400000.0
name: k1
type: LocalParameter

381953
stoichiometry: 1.0
species: COPASI24
type: SpeciesReference

383059
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

382531
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

382951
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

382867
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

383432
persistant: true
initial value: true
type: Trigger

382386
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

557194
value: 1000000.0
name: k1
type: LocalParameter

COPASI60
type: Reaction
product: 382687
reactant: 382675
kinetic law: 382699
is: SBO:0000177
reactant: 382663
is version of: GO:0006461
reversible: true
name: Tasp+A<->Tasp_A
fast: false

557203
value: 1.0
name: k2
type: LocalParameter

382325
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

383347
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

383143
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

COPASI22
type: Species
has only substance units: false
has property: MOD:00696
initial amount: NaN
initial concentration: 6.87E-8
name: Bp
is version of: P07330
constant: false
in compartment: COPASI2
boundary condition: false

557217
value: 1.0
name: k2
type: LocalParameter

381748
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

COPASI36
constant: true
value: 1.0E-7
name: asp_pulse
type: Parameter

COPASI9
has only substance units: false
has part: P07017
name: TW
boundary condition: false
is: SBO:0000253
type: Species
initial concentration: 5.91E-7
has part: P0A964
initial amount: NaN
constant: false
in compartment: COPASI2

382037
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

382446
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

557193
value: 1.0
name: k1
type: LocalParameter

557202
value: 100000.0
name: k1
type: LocalParameter

COPASI49
reactant: 382133
name: Ap+B->A+Bp
has part: http://identifiers.org/ec-code/2.7.11.1
is: SBO:0000402
product: 382169
kinetic law: 382181
has part: GO:0006470
type: Reaction
product: 382157
has part: GO:0006468
reversible: false
has part: http://identifiers.org/ec-code/3.1.3.16
fast: false
reactant: 382145

382338
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

COPASI61
is version of: GO:0006461
reactant: 382723
reactant: 382711
fast: false
is: SBO:0000177
kinetic law: 382747
product: 382735
reversible: true
name: Tasp_W+A<->Tasp_WA
type: Reaction

557216
value: 400000.0
name: k1
type: LocalParameter

COPASI21
is: SBO:0000245
has only substance units: false
type: Species
initial concentration: 1.93E-6
initial amount: NaN
is version of: P07330
name: B
constant: false
in compartment: COPASI2
boundary condition: false

COPASI35
constant: false
value: 0.701419432227109
name: Bias
type: Parameter

557183
value: 200000.0
name: kcat
type: LocalParameter

orgname: Department of Physiology, Development and Neuroscience - University of Cambridge

given: Dennis
family: Bray

ORG:
  orgname: EMBL-EBI
n:
  given: Vijayalakshmi
  family: Chelliah

W3 CDTF: Thu Mar 08 11:12:55 GMT 2012