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metaid_0000273
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264699
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262830
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264747
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262152
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263143
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263700
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metaid_0000294
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261801
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metaid_0000274
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261753
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265793
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261667
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263216
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261230
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metaid_0000275
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265479
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metaid_0000337
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260673
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260746
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265754
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262661
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262709
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metaid_0000336
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263880
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262044
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264637
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264397
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metaid_0000158
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263639
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265539
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264313
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261243
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263518
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metaid_0000159
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260539
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262770
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261972
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261558
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metaid_0000156
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260953
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262685
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260697
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262589
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264831
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264013
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263748
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metaid_0000028
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261825
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261777
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metaid_0000331
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264037
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metaid_0000351
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260833
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metaid_0000330
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262176
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262854
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263446
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metaid_0000026
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metaid_0000333
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261570
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262116
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metaid_0000290
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metaid_0000353
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264061
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metaid_0000023
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266297
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260722
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262758
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metaid_0000332
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metaid_0000291
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265407
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metaid_0000292
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263591
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metaid_0000127
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260881
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265563
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metaid_0000211
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metaid_0000042
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metaid_0000212
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261728
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264999
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metaid_0000126
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metaid_0000239
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metaid_0000021
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263301
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metaid_0000238
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262733
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metaid_0000125
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260589
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species: metaid_0000007
type: SpeciesReference

metaid_0000210
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units: metaid_0000324
value: 6.409354
type: Parameter

264253
stoichiometry: 1.0
species: metaid_0000069
type: SpeciesReference

metaid_0000124
constant: true
units: metaid_0000324
value: 0.1146248
type: Parameter

metaid_0000237
kinetic law: 261643
product: 261630
reactant: 261618
reactant: 261606
is version of: GO:0006461
fast: false
reversible: true
name: v25
type: Reaction

266131
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

metaid_0000171
constant: true
units: metaid_0000326
value: 5.54527E-5
type: Parameter

261158
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000085
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initial amount: 0.0
has part: Q02750
in compartment: metaid_0000005
is version of: C00562
initial concentration: NaN
has part: P28482
boundary condition: false
type: Species
has only substance units: true

metaid_0000198
constant: true
units: metaid_0000324
value: 9.954943
type: Parameter

metaid_0000123
constant: true
units: metaid_0000326
value: 0.002372521
type: Parameter

265988
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species: metaid_0000097
type: SpeciesReference

261947
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species: metaid_0000040
type: SpeciesReference

265587
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species: metaid_0000094
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264783
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species: metaid_0000058
type: SpeciesReference

metaid_0000170
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units: metaid_0000326
value: 1.096614E-4
type: Parameter

262394
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species: metaid_0000040
type: SpeciesReference

metaid_0000046
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constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 40000.0
in compartment: metaid_0000005
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type: Species

262332
stoichiometry: 1.0
species: metaid_0000044
type: SpeciesReference

metaid_0000086
boundary condition: false
has only substance units: true
is version of: P28482
is version of: C00562
type: Species
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265275
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

metaid_0000199
constant: true
units: metaid_0000326
value: 5.464454E-4
type: Parameter

260502
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scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

264975
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species: metaid_0000082
type: SpeciesReference

262248
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type: SpeciesReference

263663
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species: metaid_0000031
type: SpeciesReference

metaid_0000045
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constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
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type: Species

263976
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species: metaid_0000046
type: SpeciesReference

263325
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

metaid_0000196
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units: metaid_0000326
value: 6.874119E-4
type: Parameter

metaid_0000083
has part: MI:0501
name: MEKi-PP-P'ase2i
has part: Q02750
constant: false
initial amount: 0.0
in compartment: metaid_0000005
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initial concentration: NaN
boundary condition: false
has only substance units: true
type: Species

metaid_0000082
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initial concentration: NaN
in compartment: metaid_0000005
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name: MEKi-PP
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has only substance units: true
is version of: Q02750
type: Species
is version of: C00562

261327
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type: SpeciesReference

264807
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species: metaid_0000084
type: SpeciesReference

metaid_0000044
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constant: false
in compartment: metaid_0000005
type: Species
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266079
stoichiometry: 1.0
species: metaid_0000072
type: SpeciesReference

metaid_0000197
constant: true
units: metaid_0000324
value: 10.73099
type: Parameter

metaid_0000084
has only substance units: true
is version of: C00562
in compartment: metaid_0000005
name: MEKi-P-P'ase2i
type: Species
has part: MI:0501
has part: Q02750
initial concentration: NaN
boundary condition: false
constant: false
initial amount: 0.0

metaid_0000043
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has part: P62993
constant: false
name: Shc*-Grb2-Sos
boundary condition: false
type: Species
initial concentration: NaN
has only substance units: true
has part: P98077
initial amount: 0.0
in compartment: metaid_0000005

260490
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multipler: 1.0
kind: ITEM
type: SBMLUnit

261898
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species: metaid_0000042
type: SpeciesReference

metaid_0000069
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initial concentration: NaN
boundary condition: false
has part: P00533
constant: false
has part: P20936
has part: P98077
has part: P01133
type: Species

metaid_0000316
kinetic law: 265359
product: 265347
reactant: 265335
is version of: MOD:00000
fast: false
reversible: true
name: v104
type: Reaction

metaid_0000155
constant: true
units: metaid_0000324
value: 12.816
type: Parameter

261922
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

263687
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

263361
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

260977
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species: metaid_0000015
type: SpeciesReference

metaid_0000194
constant: true
units: metaid_0000324
value: 1632.425
type: Parameter

262008
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000089
initial concentration: NaN
has part: P28482
boundary condition: false
in compartment: metaid_0000005
initial amount: 0.0
has only substance units: true
type: Species
is version of: C00562
constant: false
name: ERKi-PP-P'ase3i
has part: MI:0501

metaid_0000232
kinetic law: 261413
product: 261401
reactant: 261388
reactant: 261376
is version of: GO:0006461
fast: false
reversible: true
name: v20
type: Reaction

metaid_0000219
kinetic law: 260857
product: 260845
reactant: 260833
is version of: MOD:00000
fast: false
reversible: false
name: v7
type: Reaction

265299
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

265897
stoichiometry: 1.0
species: metaid_0000070
type: SpeciesReference

metaid_0000175
constant: true
units: metaid_0000324
value: 0.2467995
type: Parameter

metaid_0000259
kinetic law: 262697
product: 262685
product: 262673
reactant: 262661
is version of: GO:0043241
fast: false
reversible: true
name: v47
type: Reaction

263772
stoichiometry: 1.0
species: metaid_0000027
type: SpeciesReference

metaid_0000317
kinetic law: 265395
product: 265383
reactant: 265371
is version of: MOD:00000
fast: false
reversible: true
name: v105
type: Reaction

metaid_0000154
constant: true
units: metaid_0000324
value: 349.772
type: Parameter

260454
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

265819
stoichiometry: 1.0
species: metaid_0000039
type: SpeciesReference

metaid_0000195
constant: true
units: metaid_0000324
value: 1489.015
type: Parameter

265832
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000231
kinetic law: 261364
product: 261352
product: 261339
reactant: 261327
is version of: GO:0043241
fast: false
reversible: true
name: v19
type: Reaction

metaid_0000174
constant: true
units: metaid_0000326
value: 1.788597E-5
type: Parameter

metaid_0000153
constant: true
units: metaid_0000326
value: 5.84737E-6
type: Parameter

265871
stoichiometry: 1.0
species: metaid_0000096
type: SpeciesReference

264121
stoichiometry: 1.0
species: metaid_0000071
type: SpeciesReference

metaid_0000314
kinetic law: 265287
product: 265275
reactant: 265263
is version of: MOD:00000
fast: false
reversible: true
name: v102
type: Reaction

metaid_0000258
kinetic law: 262649
product: 262637
reactant: 262625
reactant: 262613
is version of: GO:0006461
fast: false
reversible: true
name: v46
type: Reaction

metaid_0000067
boundary condition: false
constant: false
is version of: C00562
has part: MI:0501
initial amount: 0.0
initial concentration: NaN
type: Species
in compartment: metaid_0000005
has part: P28482
name: ERK-P-P'ase3
has only substance units: true

metaid_0000191
constant: true
units: metaid_0000324
value: 0.5985189
type: Parameter

metaid_0000230
kinetic law: 261315
product: 261303
reactant: 261291
reactant: 261279
is version of: GO:0006461
fast: false
reversible: true
name: v18
type: Reaction

metaid_0000217
kinetic law: 260783
product: 260770
product: 260758
reactant: 260746
is version of: GO:0043241
fast: false
reversible: true
name: v5
type: Reaction

metaid_0000087
boundary condition: false
in compartment: metaid_0000005
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has only substance units: true
initial amount: 0.0
is version of: C00562
type: Species
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has part: P28482
initial concentration: NaN

261194
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

260770
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000173
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units: metaid_0000324
value: 10.96212
type: Parameter

262284
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000315
kinetic law: 265323
product: 265311
reactant: 265299
is version of: MOD:00000
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reversible: true
name: v103
type: Reaction

265227
stoichiometry: 1.0
species: metaid_0000060
type: SpeciesReference

260917
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species: metaid_0000028
type: SpeciesReference

266309
stoichiometry: 1.0
species: metaid_0000073
type: SpeciesReference

metaid_0000152
constant: true
units: metaid_0000326
value: 0.004463938
type: Parameter

metaid_0000257
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product: 262589
product: 262577
reactant: 262565
is version of: GO:0043241
fast: false
reversible: true
name: v45
type: Reaction

metaid_0000192
constant: true
units: metaid_0000326
value: 0.001406622
type: Parameter

metaid_0000068
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has part: P20936
has only substance units: true
initial amount: 0.0
type: Species
boundary condition: false
has part: P00533
has part: P01133
initial concentration: NaN
name: EGF-EGFRi*^2-GAP-Shc
in compartment: metaid_0000005
constant: false

metaid_0000218
kinetic law: 260820
product: 260808
reactant: 260795
is version of: MOD:00000
fast: false
reversible: true
name: v6
type: Reaction

265083
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

metaid_0000088
name: ERKi-PP
initial amount: 0.0
is version of: C00562
type: Species
initial concentration: NaN
boundary condition: false
is version of: P28482
in compartment: metaid_0000005
constant: false
has only substance units: true

metaid_0000193
constant: true
units: metaid_0000324
value: 6340.081
type: Parameter

264541
stoichiometry: 1.0
species: metaid_0000079
type: SpeciesReference

263820
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

263023
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

metaid_0000172
constant: true
units: metaid_0000324
value: 14.19908
type: Parameter

262517
stoichiometry: 1.0
species: metaid_0000052
type: SpeciesReference

metaid_0000278
kinetic law: 263578
product: 263566
product: 263554
reactant: 263542
is version of: GO:0043241
fast: false
reversible: true
name: v66
type: Reaction

265143
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species: metaid_0000065
type: SpeciesReference

261850
stoichiometry: 1.0
species: metaid_0000040
type: SpeciesReference

metaid_0000065
is version of: MI:0501
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 1.0E7
in compartment: metaid_0000005
name: Phosphotase3
type: Species

metaid_0000312
kinetic law: 265203
product: 265191
reactant: 265179
reactant: 265167
is version of: GO:0006461
fast: false
reversible: true
name: v100
type: Reaction

metaid_0000256
kinetic law: 262553
product: 262541
reactant: 262529
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is version of: GO:0006461
fast: false
reversible: true
name: v44
type: Reaction

262200
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000151
constant: true
units: metaid_0000324
value: 11.1361
type: Parameter

263506
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species: metaid_0000024
type: SpeciesReference

261874
stoichiometry: 1.0
species: metaid_0000042
type: SpeciesReference

metaid_0000236
kinetic law: 261594
product: 261582
reactant: 261570
reactant: 261558
is version of: GO:0006461
fast: false
reversible: true
name: v24
type: Reaction

metaid_0000215
kinetic law: 260685
product: 260673
reactant: 260661
is version of: MOD:00000
fast: false
reversible: true
name: v3
type: Reaction

262493
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species: metaid_0000049
type: SpeciesReference

metaid_0000255
kinetic law: 262505
product: 262493
product: 262481
reactant: 262468
is version of: GO:0006461
fast: false
reversible: true
name: v43
type: Reaction

metaid_0000066
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constant: false
has part: MI:0501
initial amount: 0.0
initial concentration: NaN
type: Species
in compartment: metaid_0000005
is version of: C00562
has only substance units: true
name: ERK-PP-P'ase3
has part: P28482

metaid_0000190
constant: true
units: metaid_0000324
value: 51.60945
type: Parameter

metaid_0000313
kinetic law: 265251
product: 265239
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reactant: 265215
is version of: GO:0043241
fast: false
reversible: true
name: v101
type: Reaction

metaid_0000150
constant: true
units: metaid_0000326
value: 3.099213E-4
type: Parameter

metaid_0000277
kinetic law: 263530
product: 263518
reactant: 263506
reactant: 263494
is version of: GO:0006461
fast: false
reversible: true
name: v65
type: Reaction

263796
stoichiometry: 1.0
species: metaid_0000070
type: SpeciesReference

metaid_0000235
kinetic law: 261546
product: 261533
reactant: 261521
is version of: GO:0006461
fast: false
reversible: true
name: v23
type: Reaction

metaid_0000178
constant: true
units: metaid_0000326
value: 3.866434E-4
type: Parameter

261110
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species: metaid_0000019
type: SpeciesReference

263107
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species: metaid_0000065
type: SpeciesReference

264457
stoichiometry: 1.0
species: metaid_0000046
type: SpeciesReference

260478
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scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

264939
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species: metaid_0000086
type: SpeciesReference

264505
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species: metaid_0000077
type: SpeciesReference

metaid_0000216
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is version of: GO:0006461
fast: false
reversible: true
name: v4
type: Reaction

metaid_0000310
kinetic law: 265107
product: 265095
reactant: 265083
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is version of: GO:0006461
fast: false
reversible: true
name: v98
type: Reaction

metaid_0000254
kinetic law: 262456
product: 262444
reactant: 262431
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is version of: GO:0006461
fast: false
reversible: true
name: v42
type: Reaction

metaid_0000063
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initial concentration: NaN
constant: false
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type: Species
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has only substance units: true
is version of: C00562

261533
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species: metaid_0000038
type: SpeciesReference

263253
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species: metaid_0000060
type: SpeciesReference

metaid_0000177
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units: metaid_0000324
value: 1.836058
type: Parameter

metaid_0000129
constant: true
units: metaid_0000326
value: 3.047285E-5
type: Parameter

metaid_0000234
kinetic law: 261509
product: 261497
reactant: 261485
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is version of: GO:0006461
fast: false
reversible: true
name: v22
type: Reaction

264277
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species: metaid_0000045
type: SpeciesReference

metaid_0000213
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reactant: 260589
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is version of: GO:0006461
fast: false
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type: Reaction

264843
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species: metaid_0000052
type: SpeciesReference

260637
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species: metaid_0000009
type: SpeciesReference

metaid_0000253
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is version of: GO:0006461
fast: false
reversible: true
name: v41
type: Reaction

metaid_0000279
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is version of: GO:0006461
fast: false
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type: Reaction

metaid_0000064
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type: Species
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boundary condition: false
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is version of: C00562
constant: false

263844
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type: SpeciesReference

263047
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type: SpeciesReference

264565
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species: metaid_0000077
type: SpeciesReference

metaid_0000311
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reactant: 265119
is version of: GO:0043241
fast: false
reversible: true
name: v99
type: Reaction

metaid_0000128
constant: true
units: metaid_0000324
value: 2.220991
type: Parameter

metaid_0000176
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units: metaid_0000326
value: 1.283286E-4
type: Parameter

260564
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scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

metaid_0000233
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is version of: GO:0043241
fast: false
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type: Reaction

metaid_0000214
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is version of: GO:0042803
fast: false
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type: Reaction

metaid_0000168
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value: 0.9683624
type: Parameter

264661
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species: metaid_0000082
type: SpeciesReference

261960
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species: metaid_0000020
type: SpeciesReference

metaid_0000148
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value: 4.021305E-4
type: Parameter

metaid_0000261
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reactant: 262758
is version of: GO:0043241
fast: false
reversible: true
name: v49
type: Reaction

metaid_0000325
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name: itemspermin
type: SBMLUnitsDef

265467
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species: metaid_0000014
type: SpeciesReference

metaid_0000287
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is version of: GO:0006461
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name: v75
type: Reaction

260758
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species: metaid_0000023
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260661
stoichiometry: 1.0
species: metaid_0000009
type: SpeciesReference

metaid_0000169
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units: metaid_0000324
value: 931.1092
type: Parameter

263494
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

metaid_0000324
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name: permin
type: SBMLUnitsDef

metaid_0000262
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is version of: GO:0006461
fast: false
reversible: true
name: v50
type: Reaction

metaid_0000149
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units: metaid_0000324
value: 2.524092
type: Parameter

263892
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species: metaid_0000072
type: SpeciesReference

metaid_0000288
kinetic law: 264049
product: 264037
product: 264025
reactant: 264013
is version of: GO:0043241
fast: false
reversible: true
name: v76
type: Reaction

262673
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species: metaid_0000056
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263603
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species: metaid_0000024
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266223
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species: metaid_0000073
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263167
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265727
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species: metaid_0000095
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metaid_0000263
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reactant: 262854
is version of: GO:0043241
fast: false
reversible: true
name: v51
type: Reaction

261704
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species: metaid_0000041
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264735
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species: metaid_0000083
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metaid_0000323
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name: pl
type: SBMLUnitsDef

263566
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species: metaid_0000024
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264649
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species: metaid_0000077
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metaid_0000285
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product: 263892
reactant: 263880
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is version of: GO:0006461
fast: false
reversible: true
name: v73
type: Reaction

264409
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species: metaid_0000077
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264349
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species: metaid_0000035
type: SpeciesReference

261279
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species: metaid_0000031
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266171
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species: metaid_0000014
type: SpeciesReference

metaid_0000264
kinetic law: 262938
product: 262926
reactant: 262914
reactant: 262902
is version of: GO:0006461
fast: false
reversible: true
name: v52
type: Reaction

261679
stoichiometry: 1.0
species: metaid_0000041
type: SpeciesReference

263204
stoichiometry: 1.0
species: metaid_0000062
type: SpeciesReference

metaid_0000322
unit: 260454
name: min
type: SBMLUnitsDef

262999
stoichiometry: 1.0
species: metaid_0000056
type: SpeciesReference

metaid_0000286
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product: 263940
product: 263928
reactant: 263916
is version of: GO:0043241
fast: false
reversible: true
name: v74
type: Reaction

261765
stoichiometry: 1.0
species: metaid_0000046
type: SpeciesReference

265311
stoichiometry: 1.0
species: metaid_0000068
type: SpeciesReference

metaid_0000008
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name: EGF-EGFR
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initial concentration: NaN
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in compartment: metaid_0000005
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is version of: REACT 9893
type: Species

262782
stoichiometry: 1.0
species: metaid_0000058
type: SpeciesReference

metaid_0000019
is version of: P20936
is described by: http://identifiers.org/omim/139150
is version of: IPR001936
initial concentration: NaN
has only substance units: true
initial amount: 12000.0
constant: false
in compartment: metaid_0000005
boundary condition: false
type: Species
name: GAP

metaid_0000283
kinetic law: 263808
product: 263796
reactant: 263784
reactant: 263772
is version of: GO:0006461
fast: false
reversible: true
name: v71
type: Reaction

metaid_0000144
constant: true
units: metaid_0000326
value: 6.370566E-7
type: Parameter

metaid_0000329
kinetic law: 265625
product: 265612
product: 265599
reactant: 265587
is version of: GO:0043241
fast: false
reversible: true
name: v110
type: Reaction

265701
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species: metaid_0000095
type: SpeciesReference

262637
stoichiometry: 1.0
species: metaid_0000055
type: SpeciesReference

W3 CDTF: Wed May 16 15:31:52 BST 2012

metaid_0000007
is version of: P00533
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 50000.0
in compartment: metaid_0000003
name: EGFR
type: Species

metaid_0000284
kinetic law: 263856
product: 263844
reactant: 263832
reactant: 263820
is version of: GO:0006461
fast: false
reversible: true
name: v72
type: Reaction

metaid_0000059
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initial amount: 0.0
initial concentration: NaN
is version of: C00562
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constant: false
boundary condition: false
name: MEK-P-P'ase2
type: Species
has part: Q9BZL4

metaid_0000145
constant: true
units: metaid_0000324
value: 196.6479
type: Parameter

263470
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

262577
stoichiometry: 1.0
species: metaid_0000054
type: SpeciesReference

265023
stoichiometry: 1.0
species: metaid_0000087
type: SpeciesReference

metaid_0000328
kinetic law: 265575
product: 265563
reactant: 265551
reactant: 265539
is version of: GO:0006461
fast: false
reversible: true
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type: Reaction

264686
stoichiometry: 1.0
species: metaid_0000082
type: SpeciesReference

265675
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

264711
stoichiometry: 1.0
species: metaid_0000083
type: SpeciesReference

264493
stoichiometry: 1.0
species: metaid_0000052
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262140
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

262056
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species: metaid_0000020
type: SpeciesReference

metaid_0000280
kinetic law: 263675
product: 263663
product: 263651
reactant: 263639
is version of: GO:0043241
fast: false
reversible: true
name: v68
type: Reaction

265780
stoichiometry: 1.0
species: metaid_0000039
type: SpeciesReference

262974
stoichiometry: 1.0
species: metaid_0000062
type: SpeciesReference

metaid_0000281
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product: 263712
reactant: 263700
reactant: 263687
is version of: GO:0006461
fast: false
reversible: true
name: v69
type: Reaction

265741
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000327
unit: 260564
unit: 260552
unit: 260539
name: plperitempermin
type: SBMLUnitsDef

metaid_0000146
constant: true
units: metaid_0000324
value: 46468.78
type: Parameter

261255
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

metaid_0000240
kinetic law: 261789
product: 261777
reactant: 261765
reactant: 261753
is version of: GO:0006461
fast: false
reversible: true
name: v28
type: Reaction

261655
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

metaid_0000009
name: EGF-EGFR^2
type: Species
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initial concentration: NaN
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in compartment: metaid_0000005
is version of: REACT 9820
constant: false
boundary condition: false
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264325
stoichiometry: 1.0
species: metaid_0000044
type: SpeciesReference

261182
stoichiometry: 1.0
species: metaid_0000027
type: SpeciesReference

metaid_0000099
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initial concentration: NaN
constant: false
has part: CHEBI:15996
has part: P62993
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has part: P00533
has part: GO:0030119
has part: P20936
has only substance units: true
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos-Ras-GTP-Prot
in compartment: metaid_0000005
boundary condition: false
has part: Q07889

260527
exponent: -1.0
scale: 0
multipler: 1.0
kind: ITEM
type: SBMLUnit

263712
stoichiometry: 1.0
species: metaid_0000068
type: SpeciesReference

metaid_0000282
kinetic law: 263760
product: 263748
reactant: 263736
is version of: MOD:00000
fast: false
reversible: true
name: v70
type: Reaction

metaid_0000326
unit: 260527
unit: 260514
name: peritempermin
type: SBMLUnitsDef

266248
stoichiometry: 1.0
species: metaid_0000042
type: SpeciesReference

metaid_0000147
constant: true
units: metaid_0000324
value: 0.4509308
type: Parameter

metaid_0000260
kinetic law: 262746
product: 262733
reactant: 262721
reactant: 262709
is version of: GO:0006461
fast: false
reversible: true
name: v48
type: Reaction

260710
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

265047
stoichiometry: 1.0
species: metaid_0000082
type: SpeciesReference

264217
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

blabla 3
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_MEK_PP
type: Species

metaid_0000035
constant: false
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name: Grb2-Sos
initial concentration: NaN
type: Species
in compartment: metaid_0000005
initial amount: 40000.0
has part: Q07889
boundary condition: false
has only substance units: true

264073
stoichiometry: 1.0
species: metaid_0000071
type: SpeciesReference

264891
stoichiometry: 1.0
species: metaid_0000082
type: SpeciesReference

262104
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

metaid_0000098
has part: P98077
has part: CHEBI:17552
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos-Ras-GDP-Prot
constant: false
has part: Q07889
has part: P00533
has part: P01133
has part: GO:0030119
has part: P01112
in compartment: metaid_0000005
has part: P62993
has only substance units: true
has part: P20936
initial concentration: NaN
initial amount: 0.0
boundary condition: false
type: Species

metaid_0000015
initial concentration: NaN
constant: false
type: Species
boundary condition: false
has part: P01133
initial amount: 0.0
name: EGF-EGFRi
in compartment: metaid_0000005
has part: P00533
has only substance units: true

260795
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

metaid_0000004
is: GO:0005768
constant: true
size: 4.3E-6
spatial dimensions: 3.0
name: endosomal volume
type: Compartment

metaid_0000036
initial amount: 101000.0
in compartment: metaid_0000005
type: Species
boundary condition: false
has only substance units: true
initial concentration: NaN
is described by: http://identifiers.org/omim/605217
constant: false
name: Shc
is version of: P98077

264795
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

blabla 4
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_ERK_PP
type: Species

262468
stoichiometry: 1.0
species: metaid_0000051
type: SpeciesReference

metaid_0000097
in compartment: metaid_0000005
has part: P62993
has part: P98077
has part: Q07889
has only substance units: true
type: Species
boundary condition: false
has part: P20936
constant: false
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Sos-Prot
has part: P00533
initial amount: 0.0
has part: GO:0030119
has part: P01133
initial concentration: NaN

261473
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

265335
stoichiometry: 1.0
species: metaid_0000038
type: SpeciesReference

metaid_0000016
boundary condition: false
name: EGF-EGFRi^2
constant: false
type: Species
in compartment: metaid_0000005
initial amount: 0.0
has part: P00533
has part: P01133
has only substance units: true
initial concentration: NaN

metaid_0000344
kinetic law: 266333
product: 266321
product: 266309
reactant: 266297
is version of: GO:0043241
fast: false
reversible: true
name: v125
type: Reaction

metaid_0000003
is: GO:0005615
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular volume
type: Compartment

blabla 1
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_Raf*
type: Species

metaid_0000037
type: Species
in compartment: metaid_0000005
initial amount: 0.0
has part: P00533
boundary condition: false
constant: false
has only substance units: true
has part: P98077
name: EGF-EGFR*^2-GAP-Shc
initial concentration: NaN
has part: P01133
has part: P20936

263736
stoichiometry: 1.0
species: metaid_0000068
type: SpeciesReference

260869
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

262381
stoichiometry: 1.0
species: metaid_0000038
type: SpeciesReference

metaid_0000343
kinetic law: 266285
product: 266272
reactant: 266260
reactant: 266248
is version of: GO:0006461
fast: false
reversible: true
name: v124
type: Reaction

264301
stoichiometry: 1.0
species: metaid_0000070
type: SpeciesReference

metaid_0000096
initial amount: 0.0
has only substance units: true
has part: P01133
name: EGF-EGFR*^2-GAP-Shc*-Grb2-Prot
boundary condition: false
has part: P98077
type: Species
has part: P00533
has part: GO:0030119
has part: P20936
initial concentration: NaN
constant: false
in compartment: metaid_0000005
has part: P62993

metaid_0000006
type: Species
name: EGF
initial concentration: NaN
notes: 4962 molecules correspond roughly to 50 ng/ml, concentration used throughout the article (MW~6045 Da, vol=1e-12l) Similarly, 496.2 molecules correspond roughly to 5 ng/ml, 49.62 molecules correspond roughly to .5 ng/ml, 12.405 molecules correspond roughly to 0.125 ng/ml, 6.2025 molecules correspond roughly to 0.0625 ng/ml
in compartment: metaid_0000003
boundary condition: true
is version of: P01133
has only substance units: true
constant: false
initial amount: 4962.0

266118
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000130
constant: true
units: metaid_0000324
value: 0.1230832
type: Parameter

metaid_0000017
is version of: GO:0030119
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 81000.0
in compartment: metaid_0000005
name: Prot
type: Species

262950
stoichiometry: 1.0
species: metaid_0000061
type: SpeciesReference

blabla 2
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_Ras_GTP
type: Species

metaid_0000038
type: Species
in compartment: metaid_0000005
has part: P20936
has part: P00533
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
constant: false
name: EGF-EGFR*^2-GAP-Shc*
has part: P98077
has part: P01133

metaid_0000342
kinetic law: 266236
product: 266223
reactant: 266210
is version of: MOD:00000
fast: false
reversible: true
name: v123
type: Reaction

262914
stoichiometry: 1.0
species: metaid_0000056
type: SpeciesReference

262866
stoichiometry: 1.0
species: metaid_0000052
type: SpeciesReference

metaid_0000095
has part: CHEBI:15996
has part: P62993
has part: Q07889
has only substance units: true
has part: P20936
has part: P01112
boundary condition: false
type: Species
constant: false
has part: P00533
name: EGF-EGFR*^2-GAP-Grb2-Sos-Ras-GTP-Prot
has part: GO:0030119
has part: P01133
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005

metaid_0000005
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: cytoplasm
type: Compartment

metaid_0000018
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000004
name: EGFideg
type: Species

metaid_0000131
constant: false
units: metaid_0000324
value: NaN
type: Parameter

264601
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

263337
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000321
unit: 260442
name: items
type: SBMLUnitsDef

metaid_0000093
constant: false
has part: P01133
has part: Q07889
has part: P00533
in compartment: metaid_0000005
has part: GO:0030119
has part: P62993
name: EGF-EGFR*^2-GAP-Grb2-Sos-Prot
has only substance units: true
has part: P20936
type: Species
boundary condition: false
initial concentration: NaN
initial amount: 0.0

metaid_0000039
has part: P20936
name: EGF-EGFR*^2-GAP-Shc*-Grb2
initial amount: 0.0
has part: P62993
constant: false
in compartment: metaid_0000005
has part: P00533
boundary condition: false
type: Species
has only substance units: true
has part: P98077
initial concentration: NaN
has part: P01133

261582
stoichiometry: 1.0
species: metaid_0000039
type: SpeciesReference

261437
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

metaid_0000094
boundary condition: false
initial amount: 0.0
has part: P00533
has part: GO:0030119
has part: Q07889
has part: P20936
initial concentration: NaN
in compartment: metaid_0000005
has part: P01112
has part: P62993
has part: CHEBI:17552
type: Species
name: EGF-EGFR*^2-GAP-Grb2-Sos-Ras-GDP-Prot
has only substance units: true
has part: P01133
constant: false

metaid_0000011
is version of: P00533
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: EGFRi
type: Species

metaid_0000341
kinetic law: 266197
product: 266184
product: 266171
reactant: 266157
is version of: GO:0043241
fast: false
reversible: true
name: v122
type: Reaction

261497
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

262444
stoichiometry: 1.0
species: metaid_0000051
type: SpeciesReference

metaid_0000092
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: EGF-EGFRi*^2deg
type: Species

261630
stoichiometry: 1.0
species: metaid_0000040
type: SpeciesReference

metaid_0000320
kinetic law: 265527
product: 265515
reactant: 265503
is version of: MOD:00000
fast: false
reversible: true
name: v108
type: Reaction

265650
stoichiometry: 1.0
species: metaid_0000026
type: SpeciesReference

metaid_0000340
kinetic law: 266144
product: 266131
reactant: 266118
reactant: 266105
is version of: GO:0006461
fast: false
reversible: true
name: v121
type: Reaction

metaid_0000012
has part: P00533
name: EGF-EGFR*^2-GAP-Grb2-Prot
type: Species
initial amount: 0.0
boundary condition: false
has part: P01133
has part: P20936
has part: GO:0030119
initial concentration: NaN
in compartment: metaid_0000005
has part: P62993
constant: false
has only substance units: true

266157
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

265419
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000091
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: EGFRideg
type: Species

261050
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

blabla 5
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_SHC_P_t
type: Species

261813
stoichiometry: 1.0
species: metaid_0000048
type: SpeciesReference

260845
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

264951
stoichiometry: 1.0
species: metaid_0000082
type: SpeciesReference

262092
stoichiometry: 1.0
species: metaid_0000035
type: SpeciesReference

metaid_0000013
type: Species
name: EGF-EGFRi*^2
has only substance units: true
has part: P00533
has part: P01133
boundary condition: false
constant: false
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005

264025
stoichiometry: 1.0
species: metaid_0000076
type: SpeciesReference

265383
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

metaid_0000090
in compartment: metaid_0000005
type: Species
has only substance units: true
initial amount: 0.0
constant: false
boundary condition: false
has part: MI:0501
initial concentration: NaN
has part: P28482
name: ERKi-P-P'ase3i
is version of: C00562

262188
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

264759
stoichiometry: 1.0
species: metaid_0000058
type: SpeciesReference

blabla 6
constant: false
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: t_EGF_EGFR*
type: Species

263542
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

264361
stoichiometry: 1.0
species: metaid_0000069
type: SpeciesReference

261388
stoichiometry: 1.0
species: metaid_0000048
type: SpeciesReference

260808
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

265503
stoichiometry: 1.0
species: metaid_0000032
type: SpeciesReference

263940
stoichiometry: 1.0
species: metaid_0000074
type: SpeciesReference

metaid_0000014
is version of: GO:0030119
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: Proti
type: Species

263458
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000221
kinetic law: 260941
product: 260929
reactant: 260917
is version of: MOD:00000
fast: false
reversible: false
name: v9
type: Reaction

metaid_0000137
constant: true
units: metaid_0000326
value: 3803.728
type: Parameter

metaid_0000188
constant: true
units: metaid_0000326
value: 0.009688174
type: Parameter

266027
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

263964
stoichiometry: 1.0
species: metaid_0000074
type: SpeciesReference

metaid_0000249
kinetic law: 262212
product: 262200
product: 262188
reactant: 262176
is version of: GO:0043241
fast: false
reversible: true
name: v37
type: Reaction

266210
stoichiometry: 1.0
species: metaid_0000042
type: SpeciesReference

metaid_0000222
kinetic law: 260989
product: 260977
reactant: 260965
reactant: 260953
is version of: GO:0006461
fast: false
reversible: true
name: v10
type: Reaction

261206
stoichiometry: 1.0
species: metaid_0000028
type: SpeciesReference

metaid_0000136
constant: true
units: metaid_0000324
value: 0.9058936
type: Parameter

metaid_0000189
constant: true
units: metaid_0000324
value: 1.870396
type: Parameter

264157
stoichiometry: 1.0
species: metaid_0000071
type: SpeciesReference

260577
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

261074
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

264421
stoichiometry: 1.0
species: metaid_0000078
type: SpeciesReference

260893
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000010
name: EGF-EGFR*^2
is version of: C00562
has part: P01133
has only substance units: true
initial concentration: NaN
in compartment: metaid_0000005
boundary condition: false
constant: false
has part: P00533
initial amount: 0.0
type: Species

metaid_0000139
constant: true
units: metaid_0000324
value: 0.5100538
type: Parameter

265551
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000223
kinetic law: 261026
product: 261013
reactant: 261001
is version of: GO:0042803
fast: false
reversible: true
name: v11
type: Reaction

263119
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

264903
stoichiometry: 1.0
species: metaid_0000085
type: SpeciesReference

266066
stoichiometry: 1.0
species: metaid_0000041
type: SpeciesReference

metaid_0000030
has only substance units: true
in compartment: metaid_0000005
has part: P01133
has part: Q07889
type: Species
has part: P20936
has part: P62993
has part: P00533
constant: false
initial amount: 0.0
initial concentration: NaN
boundary condition: false
name: EGF-EGFR*^2-GAP-Grb2-Sos

metaid_0000138
constant: true
units: metaid_0000324
value: 171.6947
type: Parameter

265612
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

263651
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

261013
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

metaid_0000224
kinetic law: 261062
product: 261050
reactant: 261038
is version of: MOD:00000
fast: false
reversible: true
name: v12
type: Reaction

262236
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000050
is version of: P04049
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: Raf*
type: Species

262320
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

265179
stoichiometry: 1.0
species: metaid_0000086
type: SpeciesReference

263397
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

265263
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000133
constant: true
units: metaid_0000324
value: 0.294324
type: Parameter

metaid_0000184
constant: true
units: metaid_0000326
value: 7.409959E-5
type: Parameter

260601
stoichiometry: 1.0
species: metaid_0000008
type: SpeciesReference

263988
stoichiometry: 1.0
species: metaid_0000075
type: SpeciesReference

metaid_0000032
initial concentration: NaN
in compartment: metaid_0000005
has part: P62993
has part: P00533
type: Species
initial amount: 0.0
has part: P01133
has part: CHEBI:17552
has part: P20936
has part: P01112
boundary condition: false
name: EGF-EGFR*^2-GAP-Grb2-Sos-Ras-GDP
has part: Q07889
constant: false
has only substance units: true

262721
stoichiometry: 1.0
species: metaid_0000058
type: SpeciesReference

metaid_0000070
in compartment: metaid_0000005
has part: P62993
name: EGF-EGFRi*^2-GAP-Shc*-Grb2
initial concentration: NaN
constant: false
has part: P20936
boundary condition: false
has part: P98077
has only substance units: true
has part: P00533
has part: P01133
type: Species
initial amount: 0.0

260929
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

261606
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

ORG:
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n:
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  family: Chelliah

metaid_0000132
constant: true
units: metaid_0000324
value: 4.123214E-4
type: Parameter

265975
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000072
initial concentration: NaN
has part: Q07889
has only substance units: true
has part: P00533
name: EGF-EGFRi*^2-GAP-Shc*-Grb2-Sos-Ras-GDP
in compartment: metaid_0000005
has part: P01133
has part: P62993
has part: P01112
has part: P98077
type: Species
has part: CHEBI:17552
has part: P20936
boundary condition: false
constant: false
initial amount: 0.0

metaid_0000185
constant: true
units: metaid_0000324
value: 2.748877
type: Parameter

265638
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

261098
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

metaid_0000031
initial concentration: NaN
name: Ras-GDP
boundary condition: false
constant: false
has only substance units: true
in compartment: metaid_0000005
has part: CHEBI:17552
has part: P01112
initial amount: 72000.0
type: Species

261996
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species: metaid_0000043
type: SpeciesReference

metaid_0000071
has part: P00533
has part: P20936
has part: P98077
in compartment: metaid_0000005
name: EGF-EGFRi*^2-GAP-Shc*-Grb2-Sos
has part: P62993
initial concentration: NaN
has part: P01133
type: Species
initial amount: 0.0
boundary condition: false
has part: Q07889
has only substance units: true
constant: false

264133
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

262431
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

metaid_0000073
boundary condition: false
initial concentration: NaN
has part: P01133
has only substance units: true
has part: P00533
has part: P01112
has part: P98077
type: Species
constant: false
initial amount: 0.0
in compartment: metaid_0000005
has part: P20936
has part: P62993
has part: CHEBI:15996
has part: Q07889
name: EGF-EGFRi*^2-GAP-Shc*-Grb2-Sos-Ras-GTP

metaid_0000186
constant: true
units: metaid_0000324
value: 44.60169
type: Parameter

metaid_0000135
constant: true
units: metaid_0000326
value: 5.174108E-4
type: Parameter

262345
stoichiometry: 1.0
species: metaid_0000043
type: SpeciesReference

263916
stoichiometry: 1.0
species: metaid_0000072
type: SpeciesReference

261352
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

265688
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000034
has part: Q07889
has only substance units: true
initial concentration: NaN
in compartment: metaid_0000005
name: EGF-EGFR*^2-GAP-Grb2-Sos-Ras-GTP
initial amount: 0.0
has part: CHEBI:15996
type: Species
has part: P62993
has part: P00533
has part: P01133
has part: P20936
has part: P01112
constant: false
boundary condition: false

metaid_0000074
initial concentration: NaN
has only substance units: true
name: Rasi-GTP
in compartment: metaid_0000005
has part: P01112
has part: CHEBI:15996
type: Species
constant: false
initial amount: 0.0
boundary condition: false

metaid_0000134
constant: true
units: metaid_0000324
value: 0.003011324
type: Parameter

metaid_0000187
constant: true
units: metaid_0000326
value: 0.001522817
type: Parameter

260514
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

263373
stoichiometry: 1.0
species: metaid_0000092
type: SpeciesReference

265936
stoichiometry: 1.0
species: metaid_0000071
type: SpeciesReference

metaid_0000220
kinetic law: 260905
product: 260893
reactant: 260881
reactant: 260869
is version of: GO:0006461
fast: false
reversible: true
name: v8
type: Reaction

262818
stoichiometry: 1.0
species: metaid_0000054
type: SpeciesReference

metaid_0000033
name: Ras-GTP
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
type: Species
has part: P01112
has part: CHEBI:15996
constant: false
boundary condition: false

264987
stoichiometry: 1.0
species: metaid_0000086
type: SpeciesReference

ORG:
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n:
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metaid_0000055
initial amount: 0.0
in compartment: metaid_0000005
has only substance units: true
type: Species
boundary condition: false
has part: P04049
has part: Q02750
is version of: C00562
constant: false
name: MEK-P-Raf*
initial concentration: NaN

264879
stoichiometry: 1.0
species: metaid_0000060
type: SpeciesReference

metaid_0000201
constant: true
units: metaid_0000326
value: 0.003826571
type: Parameter

262541
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

263192
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

metaid_0000302
kinetic law: 264723
product: 264711
reactant: 264699
reactant: 264686
is version of: GO:0006461
fast: false
reversible: true
name: v90
type: Reaction

metaid_0000141
constant: true
units: metaid_0000324
value: 2.220991
type: Parameter

261521
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

263265
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

metaid_0000161
constant: true
units: metaid_0000324
value: 420.3359
type: Parameter

metaid_0000242
kinetic law: 261886
product: 261874
reactant: 261862
reactant: 261850
is version of: GO:0006461
fast: false
reversible: true
name: v30
type: Reaction

265845
stoichiometry: 1.0
species: metaid_0000096
type: SpeciesReference

metaid_0000229
kinetic law: 261267
product: 261255
reactant: 261243
reactant: 261230
is version of: GO:0006461
fast: false
reversible: true
name: v17
type: Reaction

metaid_0000075
has only substance units: true
has part: P01112
initial concentration: NaN
has part: P04049
name: Rafi-Rasi-GTP
type: Species
boundary condition: false
constant: false
initial amount: 0.0
in compartment: metaid_0000005
has part: CHEBI:15996

metaid_0000180
constant: true
units: metaid_0000325
value: 615.0325
type: Parameter

metaid_0000056
has only substance units: true
initial amount: 0.0
name: MEK-PP
boundary condition: false
is version of: Q02750
type: Species
initial concentration: NaN
constant: false
in compartment: metaid_0000005
is version of: C00562

metaid_0000202
constant: true
units: metaid_0000324
value: 19.85279
type: Parameter

262296
stoichiometry: 1.0
species: metaid_0000044
type: SpeciesReference

metaid_0000140
constant: true
units: metaid_0000326
value: 4.80156E-4
type: Parameter

266040
stoichiometry: 1.0
species: metaid_0000071
type: SpeciesReference

metaid_0000303
kinetic law: 264771
product: 264759
product: 264747
reactant: 264735
is version of: GO:0043241
fast: false
reversible: true
name: v91
type: Reaction

261339
stoichiometry: 1.0
species: metaid_0000033
type: SpeciesReference

metaid_0000269
kinetic law: 263179
product: 263167
product: 263155
reactant: 263143
is version of: GO:0043241
fast: false
reversible: true
name: v57
type: Reaction

264229
stoichiometry: 1.0
species: metaid_0000035
type: SpeciesReference

263832
stoichiometry: 1.0
species: metaid_0000070
type: SpeciesReference

265239
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

metaid_0000160
constant: true
units: metaid_0000324
value: 0.6220457
type: Parameter

262529
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

metaid_0000076
name: Rasi-GTP*
initial amount: 0.0
has part: P01112
type: Species
boundary condition: false
initial concentration: NaN
in compartment: metaid_0000005
constant: false
has only substance units: true
has part: CHEBI:15996

265071
stoichiometry: 1.0
species: metaid_0000088
type: SpeciesReference

260625
stoichiometry: 2.0
species: metaid_0000008
type: SpeciesReference

metaid_0000241
kinetic law: 261837
product: 261825
product: 261813
reactant: 261801
is version of: GO:0043241
fast: false
reversible: true
name: v29
type: Reaction

metaid_0000203
constant: true
units: metaid_0000324
value: 62181.84
type: Parameter

metaid_0000057
initial concentration: NaN
in compartment: metaid_0000005
has only substance units: true
type: Species
boundary condition: false
has part: Q9BZL4
has part: Q02750
name: MEK-PP-P'ase2
constant: false
is version of: C00562
initial amount: 0.0

metaid_0000181
constant: true
units: metaid_0000321
value: 7.719778E14
type: Parameter

metaid_0000318
kinetic law: 265443
product: 265431
reactant: 265419
reactant: 265407
is version of: GO:0006461
fast: false
reversible: true
name: v106
type: Reaction

262926
stoichiometry: 1.0
species: metaid_0000061
type: SpeciesReference

metaid_0000304
kinetic law: 264819
product: 264807
reactant: 264795
reactant: 264783
is version of: GO:0006461
fast: false
reversible: true
name: v92
type: Reaction

metaid_0000143
constant: true
units: metaid_0000325
value: 0.4545611
type: Parameter

metaid_0000163
constant: true
units: metaid_0000326
value: 0.007178843
type: Parameter

265131
stoichiometry: 1.0
species: metaid_0000086
type: SpeciesReference

metaid_0000182
constant: true
units: metaid_0000324
value: 29.34687
type: Parameter

260965
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

metaid_0000077
is version of: P04049
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: Rafi*
type: Species

metaid_0000244
kinetic law: 261984
product: 261972
product: 261960
reactant: 261947
is version of: GO:0043241
fast: false
reversible: true
name: v32
type: Reaction

metaid_0000204
constant: true
units: metaid_0000324
value: 1120.398
type: Parameter

261291
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

265599
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

264517
stoichiometry: 1.0
species: metaid_0000079
type: SpeciesReference

262369
stoichiometry: 1.0
species: metaid_0000035
type: SpeciesReference

metaid_0000058
is version of: MI:0501
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 40000.0
in compartment: metaid_0000005
name: Phosphatase2
type: Species

263784
stoichiometry: 1.0
species: metaid_0000069
type: SpeciesReference

262613
stoichiometry: 1.0
species: metaid_0000054
type: SpeciesReference

261146
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000142
constant: true
units: metaid_0000324
value: 31.71871
type: Parameter

metaid_0000305
kinetic law: 264867
product: 264855
product: 264843
reactant: 264831
is version of: GO:0043241
fast: false
reversible: true
name: v93
type: Reaction

metaid_0000162
constant: true
units: metaid_0000324
value: 17.39321
type: Parameter

metaid_0000183
constant: true
units: metaid_0000326
value: 5.477036E-6
type: Parameter

265191
stoichiometry: 1.0
species: metaid_0000090
type: SpeciesReference

metaid_0000319
kinetic law: 265491
product: 265479
product: 265467
reactant: 265455
is version of: GO:0043241
fast: false
reversible: true
name: v107
type: Reaction

264181
stoichiometry: 1.0
species: metaid_0000043
type: SpeciesReference

metaid_0000243
kinetic law: 261934
product: 261922
product: 261910
reactant: 261898
is version of: GO:0043241
fast: false
reversible: true
name: v31
type: Reaction

264469
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

BIOMD0000000399
units def: metaid_0000321
reaction: metaid_0000217
reaction: metaid_0000311
parameter: metaid_0000160
reaction: metaid_0000307
parameter: metaid_0000176
species: metaid_0000094
reaction: metaid_0000215
parameter: metaid_0000207
parameter: metaid_0000174
species: metaid_0000023
reaction: metaid_0000222
rule: metaid_0000465
species: metaid_0000046
compartment: metaid_0000004
species: metaid_0000017
volume units: metaid_0000323
species: metaid_0000048
reaction: metaid_0000291
reaction: metaid_0000332
reaction: metaid_0000220
reaction: metaid_0000252
rule: metaid_0000463
parameter: metaid_0000170
reaction: metaid_0000236
species: blabla 6
species: metaid_0000067
species: metaid_0000038
is version of: GO:0007173
reaction: metaid_0000289
reaction: metaid_0000303
parameter: metaid_0000152
species: metaid_0000060
parameter: metaid_0000197
parameter: metaid_0000168
reaction: metaid_0000301
parameter: metaid_0000150
parameter: metaid_0000195
reaction: metaid_0000317
species: metaid_0000077
parameter: metaid_0000166
species: metaid_0000081
parameter: metaid_0000137
species: metaid_0000022
rule: metaid_0000352
parameter: metaid_0000135
species: metaid_0000098
reaction: metaid_0000281
species: metaid_0000043
species: metaid_0000014
species: metaid_0000091
reaction: metaid_0000253
reaction: metaid_0000297
reaction: metaid_0000269
parameter: metaid_0000144
species: blabla 3
reaction: metaid_0000295
species: metaid_0000007
parameter: metaid_0000189
reaction: metaid_0000267
reaction: metaid_0000279
species: metaid_0000084
parameter: metaid_0000142
species: metaid_0000053
parameter: metaid_0000187
species: metaid_0000058
parameter: metaid_0000158
reaction: metaid_0000334
parameter: metaid_0000129
reaction: metaid_0000238
species: metaid_0000074
parameter: metaid_0000127
parameter: metaid_0000212
reaction: metaid_0000261
reaction: metaid_0000273
reaction: metaid_0000245
reaction: metaid_0000271
reaction: metaid_0000308
species: metaid_0000028
reaction: metaid_0000243

260442
exponent: 1.0
scale: 0
multipler: 1.0
kind: ITEM
type: SBMLUnit

metaid_0000078
type: Species
constant: false
boundary condition: false
initial concentration: NaN
in compartment: metaid_0000005
has part: P04049
has part: MI:0501
has only substance units: true
name: Rafi*-P'ase
initial amount: 0.0

263241
stoichiometry: 1.0
species: metaid_0000067
type: SpeciesReference

metaid_0000205
constant: true
units: metaid_0000324
value: 1.229629
type: Parameter

metaid_0000266
kinetic law: 263035
product: 263023
reactant: 263011
reactant: 262999
is version of: GO:0006461
fast: false
reversible: true
name: v54
type: Reaction

metaid_0000051
has part: P04049
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: metaid_0000005
name: Raf*-P'ase
type: Species

metaid_0000079
constant: false
has part: P04049
name: MEKi-Rafi*
initial amount: 0.0
boundary condition: false
initial concentration: NaN
in compartment: metaid_0000005
has part: Q02750
type: Species
has only substance units: true

264265
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

262565
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

264855
stoichiometry: 1.0
species: metaid_0000058
type: SpeciesReference

metaid_0000225
kinetic law: 261086
product: 261074
is version of: GO:0032800
fast: false
reversible: false
name: v13
type: Reaction

metaid_0000165
constant: true
units: metaid_0000324
value: 1.218132
type: Parameter

metaid_0000246
kinetic law: 262080
product: 262068
product: 262056
reactant: 262044
is version of: GO:0043241
fast: false
reversible: true
name: v34
type: Reaction

260552
exponent: -1.0
scale: 0
multipler: 1.0
kind: ITEM
type: SBMLUnit

264553
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

263059
stoichiometry: 1.0
species: metaid_0000064
type: SpeciesReference

metaid_0000265
kinetic law: 262987
product: 262974
product: 262962
reactant: 262950
is version of: GO:0043241
fast: false
reversible: true
name: v53
type: Reaction

metaid_0000206
constant: true
units: metaid_0000326
value: 0.004700229
type: Parameter

265095
stoichiometry: 1.0
species: metaid_0000089
type: SpeciesReference

metaid_0000052
in compartment: metaid_0000005
initial amount: 2.2E7
has only substance units: true
type: Species
boundary condition: false
initial concentration: NaN
is described by: http://identifiers.org/omim/176872
is version of: Q02750
is version of: A4QPA9
constant: false
name: MEK

metaid_0000226
kinetic law: 261134
product: 261122
reactant: 261110
reactant: 261098
is version of: GO:0006461
fast: false
reversible: true
name: v14
type: Reaction

262272
stoichiometry: 1.0
species: metaid_0000039
type: SpeciesReference

metaid_0000164
constant: true
units: metaid_0000324
value: 563.2135
type: Parameter

265215
stoichiometry: 1.0
species: metaid_0000090
type: SpeciesReference

265884
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000245
kinetic law: 262032
product: 262020
product: 262008
reactant: 261996
is version of: GO:0043241
fast: false
reversible: true
name: v33
type: Reaction

metaid_0000268
kinetic law: 263131
product: 263119
reactant: 263107
reactant: 263095
is version of: GO:0006461
fast: false
reversible: true
name: v56
type: Reaction

metaid_0000300
kinetic law: 264625
product: 264613
reactant: 264601
reactant: 264589
is version of: GO:0006461
fast: false
reversible: true
name: v88
type: Reaction

metaid_0000053
type: Species
initial amount: 0.0
in compartment: metaid_0000005
has only substance units: true
boundary condition: false
constant: false
initial concentration: NaN
has part: P04049
has part: Q02750
name: MEK-Raf*

262418
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000207
constant: true
units: metaid_0000324
value: 19.75184
type: Parameter

metaid_0000227
kinetic law: 261170
product: 261158
reactant: 261146
is version of: MOD:00000
fast: false
reversible: false
name: v15
type: Reaction

262481
stoichiometry: 1.0
species: metaid_0000046
type: SpeciesReference

metaid_0000248
kinetic law: 262164
product: 262152
reactant: 262140
is version of: MOD:00000
fast: false
reversible: false
name: v36
type: Reaction

261862
stoichiometry: 1.0
species: metaid_0000048
type: SpeciesReference

261910
stoichiometry: 1.0
species: metaid_0000040
type: SpeciesReference

metaid_0000167
constant: true
units: metaid_0000326
value: 9.826084E-6
type: Parameter

metaid_0000267
kinetic law: 263083
product: 263071
product: 263059
reactant: 263047
is version of: GO:0043241
fast: false
reversible: true
name: v55
type: Reaction

metaid_0000301
kinetic law: 264673
product: 264661
product: 264649
reactant: 264637
is version of: GO:0043241
fast: false
reversible: true
name: v89
type: Reaction

261038
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

metaid_0000289
kinetic law: 264097
product: 264085
reactant: 264073
reactant: 264061
is version of: GO:0006461
fast: false
reversible: true
name: v77
type: Reaction

metaid_0000054
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initial amount: 0.0
is version of: Q02750
name: MEK-P
initial concentration: NaN
in compartment: metaid_0000005
type: Species
is version of: C00562
has only substance units: true
is described by: http://identifiers.org/omim/176872
is version of: A4QPA9
boundary condition: false

metaid_0000208
constant: true
units: metaid_0000324
value: 0.1138168
type: Parameter

260466
exponent: 1.0
scale: -12
multipler: 1.0
kind: LITRE
type: SBMLUnit

264445
stoichiometry: 1.0
species: metaid_0000078
type: SpeciesReference

metaid_0000228
kinetic law: 261218
product: 261206
reactant: 261194
reactant: 261182
is version of: GO:0006461
fast: false
reversible: true
name: v16
type: Reaction

metaid_0000247
kinetic law: 262128
product: 262116
product: 262104
reactant: 262092
is version of: GO:0043241
fast: false
reversible: true
name: v35
type: Reaction

metaid_0000166
constant: true
units: metaid_0000326
value: 6.871213E-4
type: Parameter

264927
stoichiometry: 1.0
species: metaid_0000085
type: SpeciesReference

261122
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

W3 CDTF: Thu Nov 03 14:33:48 GMT 2011