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value: 2.0
name: g_K_ATP
type: Parameter

metaid_0000052
is: SBO:0000009
constant: true
value: 0.3
name: g_NaL
type: Parameter

BIOMD0000000378
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type: SBMLModel
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name: Chay1997_CalciumConcentration
is: MODEL0491199816
is version of: GO:0044342
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time units: 709214
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notes: This a model from the article: Effects of extracellular calcium on electrical bursting and intracellular and luminal calcium oscillations in insulin secreting pancreatic beta-cells. Chay TR Biophys J. 1997 Sep;73(3):1673-88. 9284334 , Abstract: The extracellular calcium concentration has interesting effects on bursting of pancreatic beta-cells. The mechanism underlying the extracellular Ca2+ effect is not well understood. By incorporating a low-threshold transient inward current to the store-operated bursting model of Chay, this paper elucidates the role of the extracellular Ca2+ concentration in influencing electrical activity, intracellular Ca2+ concentration, and the luminal Ca2+ concentration in the intracellular Ca2+ store. The possibility that this inward current is a carbachol-sensitive and TTX-insensitive Na+ current discovered by others is discussed. In addition, this paper explains how these three variables respond when various pharmacological agents are applied to the store-operated model. This model was taken from the CellML repository and automatically converted to SBML. The original model was: Chay TR (1997) - version05 The original CellML model was created by: Lloyd, Catherine, May c.lloyd@aukland.ac.nz The University of Auckland The Bioengineering Institute This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. For more information see the terms of use . To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
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occurs in: http://identifiers.org/taxonomy/9606
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metaid_0000058
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metaid_0000047
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metaid_0000083
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ORG:
  orgname: The University of Auckland,The Bioengineering Institute
n:
  given: Catherine
  family: Lloyd

ORG:
  orgname: EMBL-EBI
n:
  given: Ishan
  family: Ajmera

W3 CDTF: Thu Mar 08 12:59:29 GMT 2012

W3 CDTF: Thu Sep 29 23:17:54 BST 2011