709359
is: SBO:0000010
stoichiometry: 1.0
species: 2
type: SpeciesReference

709238
unit: 709250
name: substance
type: SBMLUnitsDef

709420
is: SBO:0000011
stoichiometry: 1.0
species: 6
type: SpeciesReference

709274
is: SBO:0000011
stoichiometry: 1.0
species: 2
type: SpeciesReference

709226
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

709383
is: SBO:0000011
stoichiometry: 1.0
species: 5
type: SpeciesReference

20
kinetic law: 709613
product: 709601
reactant: 709589
fast: false
reversible: false
name: R8
type: Reaction

34
constant: false
value: 0.0
name: AmAct
type: Parameter

6
is: P12259
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: Va
type: Species

24
is: SBO:0000037
constant: true
value: 122.9
name: k_PT
type: Parameter

14
kinetic law: 709335
product: 709323
reactant: 709311
fast: false
reversible: false
name: R2
type: Reaction

17
kinetic law: 709493
modifier: 709481
product: 709469
reactant: 709457
fast: false
reversible: false
name: R5
type: Reaction

10
initial amount: NaN
boundary condition: false
constant: false
type: Species
has only substance units: false
name: IIa_alpha2M
has part: P01023
initial concentration: 0.0
has part: P00734
in compartment: 35

30
is: SBO:0000025
constant: true
value: 12.4
name: kcat_2
type: Parameter

1
is: P00742
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.1999999
initial amount: NaN
in compartment: 35
name: X
type: Species

709311
is: SBO:0000010
stoichiometry: 1.0
species: 2
type: SpeciesReference

709553
is: SBO:0000010
stoichiometry: 1.0
species: 7
type: SpeciesReference

9
is: P00734
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.4
initial amount: NaN
in compartment: 35
name: II
type: Species

21
is: SBO:0000025
constant: true
value: 239.1
name: kcat_X
type: Parameter

35
constant: true
size: 1.0
spatial dimensions: 3.0
name: compartment_1
type: Compartment

25
is: SBO:0000038
constant: true
value: 801.4
name: k_PL
type: Parameter

709517
is: SBO:0000011
stoichiometry: 1.0
species: 7
type: SpeciesReference

5
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: PT
type: Species

16
kinetic law: 709445
modifier: 709433
product: 709420
reactant: 709408
fast: false
reversible: false
name: R4
type: Reaction

15
kinetic law: 709396
product: 709383
reactant: 709371
reactant: 709359
reactant: 709347
fast: false
reversible: true
name: R3
type: Reaction

709469
is: SBO:0000011
stoichiometry: 1.0
species: 7
type: SpeciesReference

11
name: IIa_ATIII
constant: false
type: Species
initial concentration: 0.0
has only substance units: false
has part: P00734
in compartment: 35
boundary condition: false
has part: P01008
initial amount: NaN

709250
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

2
is: P00742
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: Xa
type: Species

31
is: SBO:0000371
constant: true
value: 0.06148
name: km_2
type: Parameter

29
is: SBO:0000371
constant: true
value: 62.25
name: km_II
type: Parameter

22
is: SBO:0000371
constant: true
value: 23.65
name: km_X
type: Parameter

709565
is: SBO:0000011
stoichiometry: 1.0
species: 10
type: SpeciesReference

709214
unit: 709226
name: time
type: SBMLUnitsDef

32
is: SBO:0000035
constant: true
value: 0.1762
name: ki_IIaAlpha2M
type: Parameter

26
is: SBO:0000025
constant: true
value: 7.844
name: kcat_V
type: Parameter

19
kinetic law: 709577
product: 709565
reactant: 709553
fast: false
reversible: false
name: R7
type: Reaction

8
is: P12259
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.02999999
initial amount: NaN
in compartment: 35
name: V
type: Species

12
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.03
initial amount: NaN
in compartment: 35
name: RVV
type: Species

3
name: Xa_ATIII
initial amount: NaN
has part: P00742
boundary condition: false
has part: P01008
constant: false
initial concentration: 0.0
has only substance units: false
type: Species
in compartment: 35

709408
is: SBO:0000010
stoichiometry: 1.0
species: 8
type: SpeciesReference

709371
is: SBO:0000010
stoichiometry: 1.0
species: 4
type: SpeciesReference

23
is: SBO:0000035
constant: true
value: 4.531
name: ki_Xa
type: Parameter

709323
is: SBO:0000011
stoichiometry: 1.0
species: 3
type: SpeciesReference

27
is: SBO:0000371
constant: true
value: 149.7
name: km_V
type: Parameter

7
is: P00734
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 35
name: IIa
type: Species

18
kinetic law: 709541
modifier: 709529
product: 709517
reactant: 709505
fast: false
reversible: false
name: R6
type: Reaction

33
is: SBO:0000035
constant: true
value: 0.7859
name: ki_IIaATIII
type: Parameter

709505
is: SBO:0000010
stoichiometry: 1.0
species: 9
type: SpeciesReference

13
kinetic law: 709299
modifier: 709286
product: 709274
reactant: 709262
fast: false
reversible: false
name: R1
type: Reaction

709262
is: SBO:0000010
stoichiometry: 1.0
species: 1
type: SpeciesReference

4
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.04999999
initial amount: NaN
in compartment: 35
name: PL
type: Species

709347
is: SBO:0000010
stoichiometry: 1.0
species: 6
type: SpeciesReference

709589
is: SBO:0000010
stoichiometry: 1.0
species: 7
type: SpeciesReference

709601
is: SBO:0000011
stoichiometry: 1.0
species: 11
type: SpeciesReference

BIOMD0000000366
time units: 709214
species: 8
reaction: 16
substance units: 709238
is: GO:0007596
occurs in: http://identifiers.org/taxonomy/2759
reaction: 20
reaction: 13
species: 1
parameter: 22
parameter: 32
species: 12
compartment: 35
reaction: 19
species: 11
parameter: 25
parameter: 31
parameter: 29
species: 7
area units: 498119
length unit: length
reaction: 14
reaction: 17
species: 6
species: 4
units def: 709238
parameter: 23
parameter: 33
species: 10
units def: 709214
parameter: 26
name: Orfao2008_ThrombinGeneration_AmidolyticActivity
modified:
  W3 CDTF: Fri Apr 20 21:02:28 BST 2012
is: MODEL1108260000
is described by: j.jmaa.2008.05.060
type: SBMLModel
rule: 37
name: Henri-Michaelis-Menten (irreversible) kcat
volume units: 498095
reaction: 15
species: 5
species: 3
parameter: 28
parameter: 34
function def: 36
curated: true
species: 2
reaction: 18
parameter: 21
created:
  W3 CDTF: Fri Aug 26 17:38:20 BST 2011
parameter: 27
creator:
  ORG:
    orgname: EBI
  n:
    given: Michael
    family: Schubert
species: 9
parameter: 24
parameter: 30

28
is: SBO:0000025
constant: true
value: 43.87
name: kcat_II
type: Parameter

709457
is: SBO:0000010
stoichiometry: 1.0
species: 9
type: SpeciesReference