044346
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species: 891046
type: SpeciesReference

043200
stoichiometry: 1.0
species: 891052
type: SpeciesReference

891118
fast: false
reactant: 041250
kinetic law: 041274
is: SBO:0000526
reversible: false
is version of: GO:0006461
reactant: 041238
product: 041262
type: Reaction

890976
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has part: P62988
has part: IPR000608
boundary condition: false
is: SBO:0000296
type: Species
initial amount: 0.0
constant: false
has only substance units: true
in compartment: 890948

042970
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species: 890978
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044190
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species: 891088
type: SpeciesReference

891443
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constant: true
value: 1.0E-5
type: Parameter

891433
is: SBO:0000337
constant: true
value: 1.0E-8
type: Parameter

042161
stoichiometry: 1.0
species: 890978
type: SpeciesReference

045105
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species: 890984
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890986
is version of: IPR001394
is: SBO:0000014
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 200.0
in compartment: 890948
type: Species

891124
fast: false
is version of: GO:0006461
type: Reaction
reversible: false
reactant: 041335
kinetic law: 041371
product: 041359
reactant: 041347
is: SBO:0000526

ORG:
  orgname: Centre for Integrated Systems Biology of Ageing and Nutrition, Institute for Ageing and Health, Newcastle University, UK
n:
  given: Carole J
  family: Proctor

041056
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species: 891034
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890996
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constant: false
type: Species
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is: SBO:0000296

043946
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species: 891073
type: SpeciesReference

891442
is: SBO:0000337
constant: true
value: 1.0E-5
type: Parameter

890975
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in compartment: 890948
has part: P62988
has only substance units: true
type: Species
is: SBO:0000296
has part: IPR000011
initial concentration: NaN
initial amount: 0.0
constant: false

891432
is: SBO:0000337
constant: true
value: 1.0E-8
type: Parameter

891103
product: 041032
fast: false
kinetic law: 041044
reactant: 041008
is version of: GO:0006351
product: 041020
reversible: false
is: SBO:0000183
type: Reaction

890965
is version of: CHEBI:26523
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
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type: Species

043874
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species: 891061
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041992
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species: 890984
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042402
stoichiometry: 1.0
species: 890973
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041967
stoichiometry: 1.0
species: 890984
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042077
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species: 890980
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042366
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species: 890990
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042029
stoichiometry: 1.0
species: 890998
type: SpeciesReference

041347
stoichiometry: 1.0
species: 890959
type: SpeciesReference

891445
is: SBO:0000009
constant: true
value: 1.0E-5
type: Parameter

044851
stoichiometry: 1.0
species: 890973
type: SpeciesReference

042173
stoichiometry: 4.0
species: 890980
type: SpeciesReference

044007
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species: 891064
type: SpeciesReference

041432
stoichiometry: 1.0
species: 890971
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891106
is: SBO:0000183
reactant: 041056
product: 041068
product: 041080
type: Reaction
fast: false
kinetic law: 041092
reversible: false
is version of: GO:0006351

W3 CDTF: Wed Jan 27 11:31:35 GMT 2010

044358
stoichiometry: 2.0
species: 891046
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041068
stoichiometry: 1.0
species: 891034
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042342
stoichiometry: 1.0
species: 890973
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890984
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is: SBO:0000014
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 200.0
in compartment: 890948
type: Species

045067
stoichiometry: 1.0
species: 891013
type: SpeciesReference

890998
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type: Species
initial amount: 0.0
has only substance units: true
has part: P62988
has part: Q00987
boundary condition: false
initial concentration: NaN
is: SBO:0000296
in compartment: 890948

891136
product: 041590
reactant: 041566
is: SBO:0000526
fast: false
is version of: GO:0016567
reactant: 041578
kinetic law: 041615
type: Reaction
reversible: false
product: 041603

043140
stoichiometry: 1.0
species: 891049
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890978
is version of: GO:0000502
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 500.0
in compartment: 890948
type: Species

045117
stoichiometry: 1.0
species: 890980
type: SpeciesReference

891115
type: Reaction
kinetic law: 041226
is: SBO:0000180
reactant: 041190
is version of: GO:0043241
product: 041202
reversible: false
product: 041214
fast: false

041590
stoichiometry: 1.0
species: 890998
type: SpeciesReference

891444
is: SBO:0000009
constant: true
value: 1.0E-9
type: Parameter

891196
kinetic law: 042886
is: SBO:0000216
reactant: 042850
product: 042862
fast: false
is version of: GO:0016310
type: Reaction
product: 042874
reactant: 042837
reversible: false

040887
stoichiometry: 1.0
species: 890950
type: SpeciesReference

042777
stoichiometry: 1.0
species: 890994
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041445
stoichiometry: 1.0
species: 890980
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045466
stoichiometry: 1.0
species: 891040
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041359
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species: 891034
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043934
stoichiometry: 1.0
species: 891061
type: SpeciesReference

890963
is: SBO:0000405
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

044659
stoichiometry: 1.0
species: 890950
type: SpeciesReference

041190
stoichiometry: 1.0
species: 890952
type: SpeciesReference

042378
stoichiometry: 1.0
species: 890976
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040935
stoichiometry: 1.0
species: 890953
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043609
stoichiometry: 1.0
species: 891049
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043549
stoichiometry: 1.0
species: 891052
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043730
stoichiometry: 2.0
species: 891055
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041955
stoichiometry: 1.0
species: 891000
type: SpeciesReference

891052
is version of: IPR002955
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

045031
stoichiometry: 1.0
species: 890984
type: SpeciesReference

043104
stoichiometry: 1.0
species: 891058
type: SpeciesReference

891193
product: 042813
product: 042801
is: SBO:0000216
fast: false
is version of: GO:0016310
type: Reaction
reversible: false
kinetic law: 042825
reactant: 042789
reactant: 042777

041918
stoichiometry: 1.0
species: 890984
type: SpeciesReference

041032
stoichiometry: 1.0
species: 890953
type: SpeciesReference

042330
stoichiometry: 1.0
species: 890990
type: SpeciesReference

041383
stoichiometry: 1.0
species: 891034
type: SpeciesReference

891100
product: 040984
is: SBO:0000183
reversible: false
is version of: GO:0006351
product: 040972
type: Reaction
fast: false
kinetic law: 040996
reactant: 040960

042439
stoichiometry: 1.0
species: 890976
type: SpeciesReference

891013
boundary condition: false
has only substance units: true
has part: Q00987
initial amount: 0.0
initial concentration: NaN
constant: false
type: Species
is: SBO:0000296
has part: P62988
in compartment: 890948

044887
stoichiometry: 1.0
species: 890976
type: SpeciesReference

042789
stoichiometry: 1.0
species: 891028
type: SpeciesReference

W3 CDTF: Fri Mar 09 15:49:24 GMT 2012

042704
stoichiometry: 1.0
species: 890988
type: SpeciesReference

045141
stoichiometry: 1.0
species: 891010
type: SpeciesReference

043537
stoichiometry: 1.0
species: 891070
type: SpeciesReference

043898
stoichiometry: 2.0
species: 891061
type: SpeciesReference

042053
stoichiometry: 1.0
species: 890950
type: SpeciesReference

890961
is version of: Q00987
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

890971
is version of: IPR000011
is: SBO:0000014
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 100.0
in compartment: 890948
type: Species

891090
kinetic law: 040815
product: 040803
reactant: 040791
is version of: GO:0006351
is: SBO:0000183
fast: false
reversible: false
type: Reaction

041457
stoichiometry: 1.0
species: 891076
type: SpeciesReference

043694
stoichiometry: 1.0
species: 891061
type: SpeciesReference

045430
stoichiometry: 1.0
species: 891043
type: SpeciesReference

044250
stoichiometry: 1.0
species: 891037
type: SpeciesReference

891127
reactant: 041383
fast: false
product: 041408
type: Reaction
is version of: GO:0043241
reversible: false
product: 041395
is: SBO:0000180
kinetic law: 041420

890988
is: SBO:0000296
constant: false
has part: P62988
has part: Q00987
initial concentration: NaN
initial amount: 0.0
type: Species
has part: P04637
in compartment: 890948
has only substance units: true
boundary condition: false

891391
is: SBO:0000337
constant: true
value: 0.001155
type: Parameter

891441
is: SBO:0000337
constant: true
value: 0.001
type: Parameter

891112
is: SBO:0000526
product: 041166
reactant: 041154
type: Reaction
reversible: false
reactant: 041142
fast: false
kinetic law: 041178
is version of: GO:0006461

041395
stoichiometry: 1.0
species: 891028
type: SpeciesReference

045043
stoichiometry: 1.0
species: 890980
type: SpeciesReference

891091
kinetic law: 040851
product: 040839
reactant: 040827
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: false
type: Reaction

891040
is version of: GO:0000502
is version of: P05067
in compartment: 890948
type: Species
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
is: SBO:0000296
constant: false

044911
stoichiometry: 1.0
species: 890973
type: SpeciesReference

891190
fast: false
is version of: GO:0016567
kinetic law: 042765
reversible: false
type: Reaction
product: 042740
product: 042728
is: SBO:0000526
product: 042753
reactant: 042704
reactant: 042716

891421
is: SBO:0000009
constant: true
value: 0.1
type: Parameter

044875
stoichiometry: 1.0
species: 891010
type: SpeciesReference

042427
stoichiometry: 1.0
species: 890992
type: SpeciesReference

044334
stoichiometry: 1.0
species: 891043
type: SpeciesReference

044056
stoichiometry: 1.0
species: 891031
type: SpeciesReference

891392
is: SBO:0000282
constant: true
value: 1.155E-5
type: Parameter

043910
stoichiometry: 2.0
species: 891073
type: SpeciesReference

043297
stoichiometry: 1.0
species: 891049
type: SpeciesReference

041469
stoichiometry: 1.0
species: 890975
type: SpeciesReference

891440
is: SBO:0000337
constant: true
value: 1.0E-8
type: Parameter

041979
stoichiometry: 1.0
species: 890998
type: SpeciesReference

890973
is version of: IPR000608
is: SBO:0000014
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 100.0
in compartment: 890948
type: Species

045153
stoichiometry: 1.0
species: 890984
type: SpeciesReference

042065
stoichiometry: 1.0
species: 890984
type: SpeciesReference

891420
is: SBO:0000009
constant: true
value: 0.5
type: Parameter

044262
stoichiometry: 1.0
species: 891043
type: SpeciesReference

891010
in compartment: 890948
constant: false
type: Species
is: SBO:0000296
boundary condition: false
has only substance units: true
has part: Q00987
initial concentration: NaN
initial amount: 0.0
has part: P62988

043826
stoichiometry: 2.0
species: 891061
type: SpeciesReference

043525
stoichiometry: 1.0
species: 891055
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891139
kinetic law: 041677
reactant: 041639
product: 041664
is version of: GO:0016567
type: Reaction
reversible: false
product: 041652
is: SBO:0000526
reactant: 041627
fast: false

045442
stoichiometry: 1.0
species: 890965
type: SpeciesReference

041541
stoichiometry: 1.0
species: 890971
type: SpeciesReference

891000
has part: P62988
is: SBO:0000296
in compartment: 890948
type: Species
initial amount: 0.0
boundary condition: false
has only substance units: true
has part: Q00987
initial concentration: NaN
constant: false

044995
stoichiometry: 1.0
species: 891016
type: SpeciesReference

044635
stoichiometry: 1.0
species: 890951
type: SpeciesReference

891387
is: SBO:0000009
constant: true
value: 7.0E-4
type: Parameter

891413
is: SBO:0000349
constant: true
value: 5.0E-4
type: Parameter

891022
has part: P62988
initial amount: 0.0
in compartment: 890948
type: Species
has part: GO:0000502
is: SBO:0000296
initial concentration: NaN
has only substance units: true
has part: Q00987
boundary condition: false
constant: false

043814
stoichiometry: 2.0
species: 891049
type: SpeciesReference

040827
stoichiometry: 1.0
species: 890954
type: SpeciesReference

891423
is: SBO:0000009
constant: true
value: 2.0E-4
type: Parameter

044479
stoichiometry: 1.0
species: 891088
type: SpeciesReference

041809
stoichiometry: 1.0
species: 891004
type: SpeciesReference

044539
stoichiometry: 1.0
species: 890955
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042221
stoichiometry: 1.0
species: 890954
type: SpeciesReference

043417
stoichiometry: 1.0
species: 891049
type: SpeciesReference

891257
reversible: false
product: 044007
fast: false
reactant: 043995
is version of: GO:0008539
is: SBO:0000169
reactant: 043983
type: Reaction
kinetic law: 044019

041905
stoichiometry: 1.0
species: 891000
type: SpeciesReference

043285
stoichiometry: 1.0
species: 891034
type: SpeciesReference

891393
is: SBO:0000337
constant: true
value: 2.0E-6
type: Parameter

041833
stoichiometry: 1.0
species: 891002
type: SpeciesReference

891412
is: SBO:0000363
constant: true
value: 1.0E-4
type: Parameter

891388
is: SBO:0000009
constant: true
value: 0.007
type: Parameter

041773
stoichiometry: 1.0
species: 891004
type: SpeciesReference

042632
stoichiometry: 1.0
species: 890990
type: SpeciesReference

043585
stoichiometry: 1.0
species: 891052
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044044
stoichiometry: 1.0
species: 891037
type: SpeciesReference

041566
stoichiometry: 1.0
species: 890950
type: SpeciesReference

891037
is version of: P05067
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

891043
is version of: P05067
is: SBO:0000296
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

045526
stoichiometry: 1.0
species: 890965
type: SpeciesReference

040791
stoichiometry: 1.0
species: 891085
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041214
stoichiometry: 1.0
species: 890950
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045237
stoichiometry: 1.0
species: 890961
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891256
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is version of: GO:0051787
kinetic law: 043970
reversible: false
product: 043958
reactant: 043934
is: SBO:0000526
fast: false
type: Reaction

891394
is: SBO:0000282
constant: true
value: 0.002
type: Parameter

044587
stoichiometry: 1.0
species: 890959
type: SpeciesReference

891034
constant: false
has part: P04637
in compartment: 890948
type: Species
initial amount: 0.0
initial concentration: NaN
is: SBO:0000296
has only substance units: true
has part: P49841
boundary condition: false

042536
stoichiometry: 1.0
species: 890980
type: SpeciesReference

043501
stoichiometry: 1.0
species: 891055
type: SpeciesReference

891411
is: SBO:0000009
constant: true
value: 2.0E-5
type: Parameter

040839
stoichiometry: 1.0
species: 891088
type: SpeciesReference

891385
is: SBO:0000009
constant: true
value: 5.0E-4
type: Parameter

891425
is: SBO:0000337
constant: true
value: 0.1
type: Parameter

044971
stoichiometry: 1.0
species: 890973
type: SpeciesReference

044031
stoichiometry: 1.0
species: 891031
type: SpeciesReference

041286
stoichiometry: 1.0
species: 891031
type: SpeciesReference

045261
stoichiometry: 1.0
species: 890980
type: SpeciesReference

891269
kinetic law: 044491
product: 044479
reactant: 044467
is version of: GO:0006281
is: SBO:0000179
fast: false
reversible: false
type: Reaction

041821
stoichiometry: 1.0
species: 890984
type: SpeciesReference

891259
product: 044092
kinetic law: 044116
is version of: GO:0034205
reactant: 044080
fast: false
type: Reaction
product: 044104
reversible: false
is: SBO:0000393

044527
stoichiometry: 1.0
species: 890969
type: SpeciesReference

891395
is: SBO:0000009
constant: true
value: 4.95E-4
type: Parameter

043429
stoichiometry: 1.0
species: 891028
type: SpeciesReference

041578
stoichiometry: 1.0
species: 890976
type: SpeciesReference

045333
stoichiometry: 1.0
species: 891025
type: SpeciesReference

891025
constant: false
has part: GO:0000502
has part: P62988
type: Species
has only substance units: true
in compartment: 890948
initial amount: 0.0
is: SBO:0000296
has part: Q00987
boundary condition: false
initial concentration: NaN

891238
kinetic law: 043670
product: 043658
reactant: 043646
is version of: GO:0070841
is: SBO:0000526
fast: false
reversible: false
type: Reaction

891410
is: SBO:0000009
constant: true
value: 0.08
type: Parameter

891386
is: SBO:0000356
constant: true
value: 5.0E-4
type: Parameter

041761
stoichiometry: 1.0
species: 890976
type: SpeciesReference

043597
stoichiometry: 1.0
species: 891070
type: SpeciesReference

891424
is: SBO:0000009
constant: true
value: 0.01
type: Parameter

042644
stoichiometry: 1.0
species: 890982
type: SpeciesReference

891268
kinetic law: 044455
modifier: 044443
product: 044431
is version of: GO:0006950
is: SBO:0000357
fast: false
reversible: false
type: Reaction

043188
stoichiometry: 1.0
species: 891031
type: SpeciesReference

045249
stoichiometry: 1.0
species: 890984
type: SpeciesReference

044599
stoichiometry: 1.0
species: 890955
type: SpeciesReference

045538
stoichiometry: 1.0
species: 890969
type: SpeciesReference

891438
is: SBO:0000282
constant: true
value: 1.0E-4
type: Parameter

891055
is version of: IPR002955
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

891258
product: 044044
reversible: false
fast: false
product: 044056
type: Reaction
kinetic law: 044068
is: SBO:0000393
is version of: GO:0034205
reactant: 044031

891396
is: SBO:0000356
constant: true
value: 0.01
type: Parameter

043237
stoichiometry: 1.0
species: 891052
type: SpeciesReference

891427
is: SBO:0000009
constant: true
value: 8.0E-5
type: Parameter

891383
is: SBO:0000009
constant: true
value: 0.001
type: Parameter

BIOMD0000000286
reaction: 891196
rule: metaid_0000049
reaction: 891184
reaction: 891190
reaction: 891275
reaction: 891291
reaction: 891229
reaction: 891250
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reaction: 891259
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reaction: 891281
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parameter: 891438
reaction: 891166
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reaction: 891094
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species: 891002
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reaction: 891241
reaction: 891235
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species: 891070
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reaction: 891142
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species: 891076
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species: 891040
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reaction: 891163
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reaction: 891157
species: 890971
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is version of: DOID:10652
species: 891079
reaction: 891260
reaction: 891133

041250
stoichiometry: 1.0
species: 890951
type: SpeciesReference

891247
product: 043790
type: Reaction
reactant: 043766
kinetic law: 043802
fast: false
is: SBO:0000526
reversible: false
reactant: 043778
is version of: GO:0070841

043261
stoichiometry: 1.0
species: 891055
type: SpeciesReference

041857
stoichiometry: 1.0
species: 890980
type: SpeciesReference

891417
is: SBO:0000009
constant: true
value: 2.0
type: Parameter

891397
is: SBO:0000337
constant: true
value: 2.0E-4
type: Parameter

891409
is: SBO:0000337
constant: true
value: 0.00456
type: Parameter

891437
is: SBO:0000261
constant: true
value: 1.0E-5
type: Parameter

891046
is version of: P05067
is: SBO:0000296
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

044792
stoichiometry: 1.0
species: 890973
type: SpeciesReference

044515
stoichiometry: 1.0
species: 890957
type: SpeciesReference

040803
stoichiometry: 1.0
species: 890954
type: SpeciesReference

891426
is: SBO:0000282
constant: true
value: 1.0E-4
type: Parameter

891148
product: 041845
product: 041833
reversible: false
kinetic law: 041869
product: 041857
is version of: GO:0016567
is: SBO:0000526
fast: false
type: Reaction
reactant: 041821
reactant: 041809

891232
is version of: GO:0016310
reactant: 043537
type: Reaction
reactant: 043525
reversible: false
fast: false
kinetic law: 043573
is: SBO:0000330
product: 043549
product: 043561

891384
is: SBO:0000356
constant: true
value: 1.0E-4
type: Parameter

043176
stoichiometry: 1.0
species: 891049
type: SpeciesReference

045213
stoichiometry: 1.0
species: 891007
type: SpeciesReference

890969
is version of: CHEBI:16991
is: SBO:0000251
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

891416
is: SBO:0000009
constant: true
value: 0.5
type: Parameter

043224
stoichiometry: 1.0
species: 891031
type: SpeciesReference

891408
is: SBO:0000337
constant: true
value: 6.84E-6
type: Parameter

891436
is: SBO:0000337
constant: true
value: 5.0E-5
type: Parameter

042656
stoichiometry: 1.0
species: 890988
type: SpeciesReference

042740
stoichiometry: 1.0
species: 890982
type: SpeciesReference

041238
stoichiometry: 1.0
species: 891028
type: SpeciesReference

045490
stoichiometry: 1.0
species: 890965
type: SpeciesReference

043561
stoichiometry: 1.0
species: 891070
type: SpeciesReference

891446
is: SBO:0000009
constant: false
value: 1.0
type: Parameter

041845
stoichiometry: 1.0
species: 890984
type: SpeciesReference

045285
stoichiometry: 1.0
species: 891016
type: SpeciesReference

891415
is: SBO:0000009
constant: true
value: 2.0E-4
type: Parameter

043249
stoichiometry: 1.0
species: 891031
type: SpeciesReference

043405
stoichiometry: 1.0
species: 891028
type: SpeciesReference

041262
stoichiometry: 1.0
species: 891031
type: SpeciesReference

891235
kinetic law: 043634
type: Reaction
product: 043609
is: SBO:0000330
reactant: 043597
is version of: GO:0016310
fast: false
reactant: 043585
product: 043621
reversible: false

891407
is: SBO:0000337
constant: true
value: 4.56E-6
type: Parameter

044780
stoichiometry: 1.0
species: 891007
type: SpeciesReference

044467
stoichiometry: 1.0
species: 890969
type: SpeciesReference

891435
is: SBO:0000337
constant: true
value: 0.001
type: Parameter

044503
stoichiometry: 1.0
species: 890969
type: SpeciesReference

042753
stoichiometry: 1.0
species: 890980
type: SpeciesReference

891429
is: SBO:0000356
constant: true
value: 0.01
type: Parameter

891399
is: SBO:0000337
constant: true
value: 0.001
type: Parameter

891199
is: SBO:0000216
kinetic law: 042946
reactant: 042898
is version of: GO:0016310
type: Reaction
reactant: 042910
product: 042922
reversible: false
fast: false
product: 042934

043958
stoichiometry: 2.0
species: 891073
type: SpeciesReference

891058
is version of: IPR015562
is: SBO:0000296
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 100.0
in compartment: 890948
type: Species

042668
stoichiometry: 1.0
species: 890982
type: SpeciesReference

041505
stoichiometry: 1.0
species: 890973
type: SpeciesReference

891244
kinetic law: 043754
product: 043742
reactant: 043730
is version of: GO:0070841
is: SBO:0000526
fast: false
reversible: false
type: Reaction

045225
stoichiometry: 1.0
species: 890984
type: SpeciesReference

891031
has part: P49841
is: SBO:0000296
has only substance units: true
in compartment: 890948
constant: false
boundary condition: false
type: Species
initial amount: 0.0
has part: P04637
initial concentration: NaN

890967
is version of: CHEBI:26523
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 10.0
in compartment: 890948
type: Species

891109
kinetic law: 041129
product: 041117
reactant: 041104
is version of: GO:0009056
is: SBO:0000279
fast: false
reversible: false
type: Reaction

043164
stoichiometry: 1.0
species: 891031
type: SpeciesReference

042004
stoichiometry: 1.0
species: 890980
type: SpeciesReference

891049
is version of: IPR002955
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

891434
is: SBO:0000337
constant: true
value: 1.0E-7
type: Parameter

041689
stoichiometry: 1.0
species: 891000
type: SpeciesReference

891428
is: SBO:0000337
constant: true
value: 1.925E-7
type: Parameter

042281
stoichiometry: 1.0
species: 890973
type: SpeciesReference

045382
stoichiometry: 1.0
species: 890955
type: SpeciesReference

040911
stoichiometry: 1.0
species: 890951
type: SpeciesReference

891295
kinetic law: 045636
product: 045624
reactant: 045612
is version of: GO:0006412
is: SBO:0000393
fast: false
reversible: false
type: Reaction

891260
reversible: false
is version of: GO:0008539
fast: false
reactant: 044141
reactant: 044128
type: Reaction
product: 044153
is: SBO:0000169
kinetic law: 044165

042101
stoichiometry: 1.0
species: 891004
type: SpeciesReference

041166
stoichiometry: 1.0
species: 890952
type: SpeciesReference

891281
reversible: false
product: 045019
is version of: GO:0016579
fast: false
reactant: 045007
is: SBO:0000526
product: 045043
kinetic law: 045055
type: Reaction
reactant: 044995
product: 045031

891274
is: SBO:0000216
product: 044696
is version of: GO:0016310
type: Reaction
reactant: 044671
fast: false
product: 044683
reversible: false
kinetic law: 044708
reactant: 044659

042850
stoichiometry: 1.0
species: 891031
type: SpeciesReference

040972
stoichiometry: 1.0
species: 890959
type: SpeciesReference

891019
in compartment: 890948
has only substance units: true
boundary condition: false
has part: P62988
is: SBO:0000296
constant: false
initial concentration: NaN
initial amount: 0.0
has part: P04637
type: Species
has part: GO:0000502

890957
is version of: Q13315
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 200.0
in compartment: 890948
type: Species

891404
is: SBO:0000282
constant: true
value: 1.0E-4
type: Parameter

044839
stoichiometry: 1.0
species: 891010
type: SpeciesReference

041785
stoichiometry: 1.0
species: 890973
type: SpeciesReference

045309
stoichiometry: 1.0
species: 891025
type: SpeciesReference

891389
is: SBO:0000356
constant: true
value: 0.005
type: Parameter

891294
product: 045588
product: 045575
reactant: 045563
is: SBO:0000176
is version of: GO:0034614
kinetic law: 045600
reversible: false
type: Reaction
fast: false

042608
stoichiometry: 1.0
species: 890980
type: SpeciesReference

041701
stoichiometry: 1.0
species: 890976
type: SpeciesReference

891261
kinetic law: 044202
product: 044190
reactant: 044178
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: false
type: Reaction

891175
product: 042390
reactant: 042366
is: SBO:0000526
is version of: GO:0016567
product: 042402
reversible: false
kinetic law: 042415
reactant: 042378
fast: false
type: Reaction

891275
kinetic law: 044744
product: 044732
reactant: 044720
is version of: GO:0016310
is: SBO:0000330
fast: false
reversible: false
type: Reaction

043056
stoichiometry: 1.0
species: 890978
type: SpeciesReference

891280
type: Reaction
kinetic law: 044983
fast: false
is: SBO:0000526
is version of: GO:0016567
reversible: false
reactant: 044947
product: 044971
reactant: 044935
product: 044959

891169
reactant: 042257
is version of: GO:0016567
kinetic law: 042293
reversible: false
is: SBO:0000526
type: Reaction
reactant: 042245
product: 042269
fast: false
product: 042281

043465
stoichiometry: 1.0
species: 891028
type: SpeciesReference

891405
is: SBO:0000282
constant: true
value: 1.0E-7
type: Parameter

043646
stoichiometry: 2.0
species: 891052
type: SpeciesReference

891205
reactant: 043032
product: 043068
is: SBO:0000180
fast: false
is version of: GO:0030163
reactant: 043020
type: Reaction
kinetic law: 043080
product: 043044
product: 043056
reversible: false

891241
is: SBO:0000526
fast: false
is version of: GO:0070841
type: Reaction
product: 043706
reversible: false
reactant: 043682
reactant: 043694
kinetic law: 043718

045007
stoichiometry: 1.0
species: 890984
type: SpeciesReference

891255
kinetic law: 043922
product: 043910
reactant: 043898
is version of: GO:0051787
is: SBO:0000526
fast: false
reversible: false
type: Reaction

043309
stoichiometry: 1.0
species: 891034
type: SpeciesReference

891178
reactant: 042439
reactant: 042427
is: SBO:0000526
product: 042451
is version of: GO:0016567
kinetic law: 042475
product: 042463
type: Reaction
fast: false
reversible: false

042113
stoichiometry: 1.0
species: 890978
type: SpeciesReference

891293
type: Reaction
kinetic law: 045550
reactant: 045514
product: 045538
is version of: GO:0034614
reversible: false
fast: false
product: 045526
is: SBO:0000176

891418
is: SBO:0000009
constant: true
value: 0.5
type: Parameter

045394
stoichiometry: 1.0
species: 890957
type: SpeciesReference

891283
reactant: 045153
reversible: false
product: 045177
fast: false
is: SBO:0000526
is version of: GO:0016579
type: Reaction
product: 045165
reactant: 045141
product: 045189
kinetic law: 045201

040923
stoichiometry: 1.0
species: 890951
type: SpeciesReference

891272
is version of: GO:0016310
reversible: false
product: 044599
fast: false
product: 044587
reactant: 044563
type: Reaction
is: SBO:0000216
reactant: 044575
kinetic law: 044611

890955
is version of: Q13315
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

041893
stoichiometry: 1.0
species: 890984
type: SpeciesReference

891402
is: SBO:0000337
constant: true
value: 2.0E-6
type: Parameter

043706
stoichiometry: 2.0
species: 891061
type: SpeciesReference

040984
stoichiometry: 1.0
species: 890953
type: SpeciesReference

042862
stoichiometry: 1.0
species: 890996
type: SpeciesReference

045345
stoichiometry: 1.0
species: 890978
type: SpeciesReference

891187
is version of: GO:0016567
reversible: false
reactant: 042632
fast: false
product: 042680
product: 042656
reactant: 042644
product: 042668
is: SBO:0000526
type: Reaction
kinetic law: 042692

041603
stoichiometry: 1.0
species: 890973
type: SpeciesReference

043068
stoichiometry: 1.0
species: 891079
type: SpeciesReference

891263
kinetic law: 044238
product: 044226
reactant: 044214
is version of: GO:0051787
is: SBO:0000526
fast: false
reversible: false
type: Reaction

891292
product: 045490
fast: false
type: Reaction
product: 045478
kinetic law: 045502
reactant: 045466
is: SBO:0000393
reversible: false
is version of: GO:0052064

891419
is: SBO:0000009
constant: true
value: 0.005
type: Parameter

891282
product: 045092
fast: false
is: SBO:0000526
product: 045105
reactant: 045080
reactant: 045067
kinetic law: 045129
is version of: GO:0016579
product: 045117
type: Reaction
reversible: false

044431
stoichiometry: 1.0
species: 890969
type: SpeciesReference

042934
stoichiometry: 1.0
species: 891034
type: SpeciesReference

891273
kinetic law: 044647
product: 044635
reactant: 044623
is version of: GO:0016310
is: SBO:0000330
fast: false
reversible: false
type: Reaction

metaid_0000215
constant: false
value: NaN
name: tot_mdm2
type: Parameter

891253
reversible: false
kinetic law: 043886
product: 043874
is: SBO:0000526
reactant: 043850
fast: false
reactant: 043862
type: Reaction
is version of: GO:0070841

044828
stoichiometry: 1.0
species: 890976
type: SpeciesReference

891403
is: SBO:0000282
constant: true
value: 1.0E-7
type: Parameter

042318
stoichiometry: 1.0
species: 890976
type: SpeciesReference

044178
stoichiometry: 1.0
species: 891037
type: SpeciesReference

042500
stoichiometry: 1.0
species: 890982
type: SpeciesReference

043369
stoichiometry: 1.0
species: 891034
type: SpeciesReference

891157
type: Reaction
is: SBO:0000526
kinetic law: 042089
product: 042065
is version of: GO:0016567
reactant: 042041
product: 042077
fast: false
product: 042053
reversible: false
reactant: 042029

045297
stoichiometry: 1.0
species: 890978
type: SpeciesReference

metaid_0000216
constant: false
value: NaN
name: tot_p53
type: Parameter

043995
stoichiometry: 1.0
species: 890978
type: SpeciesReference

044407
stoichiometry: 1.0
species: 891037
type: SpeciesReference

045696
stoichiometry: 1.0
species: 891067
type: SpeciesReference

042874
stoichiometry: 1.0
species: 891031
type: SpeciesReference

043682
stoichiometry: 1.0
species: 891052
type: SpeciesReference

044575
stoichiometry: 1.0
species: 890955
type: SpeciesReference

043621
stoichiometry: 1.0
species: 891070
type: SpeciesReference

891079
is version of: CHEBI:16761
constant: true
boundary condition: true
has only substance units: true
initial concentration: NaN
initial amount: 1000.0
in compartment: 890948
type: Species

891291
is version of: GO:0052064
kinetic law: 045454
type: Reaction
product: 045442
is: SBO:0000393
reactant: 045418
reversible: false
fast: false
product: 045430

041881
stoichiometry: 1.0
species: 891002
type: SpeciesReference

045514
stoichiometry: 1.0
species: 890965
type: SpeciesReference

891264
reactant: 044250
is: SBO:0000526
product: 044274
type: Reaction
reactant: 044262
fast: false
reversible: false
kinetic law: 044286
is version of: GO:0051787

041202
stoichiometry: 1.0
species: 890951
type: SpeciesReference

044153
stoichiometry: 1.0
species: 891040
type: SpeciesReference

891208
is version of: GO:0048156
reversible: false
kinetic law: 043116
product: 043104
is version of: GO:0008017
fast: false
type: Reaction
is: SBO:0000526
reactant: 043092

041529
stoichiometry: 1.0
species: 890976
type: SpeciesReference

891166
reversible: false
type: Reaction
is version of: GO:0006412
reactant: 042197
kinetic law: 042233
product: 042209
fast: false
product: 042221
is: SBO:0000393

891290
kinetic law: 045406
product: 045394
reactant: 045382
is version of: GO:0006464
is: SBO:0000176
fast: false
reversible: false
type: Reaction

041481
stoichiometry: 1.0
species: 891082
type: SpeciesReference

891400
is: SBO:0000337
constant: true
value: 5.0E-5
type: Parameter

891250
kinetic law: 043838
product: 043826
reactant: 043814
is version of: GO:0070841
is: SBO:0000526
fast: false
reversible: false
type: Reaction

042125
stoichiometry: 1.0
species: 891022
type: SpeciesReference

042596
stoichiometry: 1.0
species: 890982
type: SpeciesReference

043441
stoichiometry: 1.0
species: 891052
type: SpeciesReference

045418
stoichiometry: 1.0
species: 891043
type: SpeciesReference

891265
kinetic law: 044322
product: 044310
reactant: 044298
is version of: GO:0005914
is: SBO:0000526
fast: false
reversible: false
type: Reaction

891279
kinetic law: 044923
is: SBO:0000526
is version of: GO:0016567
reversible: false
type: Reaction
reactant: 044887
fast: false
product: 044911
reactant: 044875
product: 044899

891229
product: 043489
fast: false
reactant: 043465
is version of: GO:0016310
product: 043501
reactant: 043477
reversible: false
type: Reaction
is: SBO:0000216
kinetic law: 043513

044899
stoichiometry: 1.0
species: 891013
type: SpeciesReference

042512
stoichiometry: 1.0
species: 890992
type: SpeciesReference

044816
stoichiometry: 1.0
species: 891007
type: SpeciesReference

043357
stoichiometry: 1.0
species: 891052
type: SpeciesReference

891028
is version of: P49841
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 500.0
in compartment: 890948
type: Species

043032
stoichiometry: 1.0
species: 891076
type: SpeciesReference

041020
stoichiometry: 1.0
species: 891031
type: SpeciesReference

041725
stoichiometry: 1.0
species: 890973
type: SpeciesReference

890948
is version of: GO:0005623
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0
type: Compartment

891401
is: SBO:0000337
constant: true
value: 0.01
type: Parameter

041639
stoichiometry: 1.0
species: 890976
type: SpeciesReference

891151
reactant: 041881
kinetic law: 041943
type: Reaction
reactant: 041893
is: SBO:0000526
reversible: false
product: 041930
fast: false
product: 041918
is version of: GO:0016567
product: 041905

891067
initial concentration: NaN
constant: false
has only substance units: true
boundary condition: false
has part: GO:0000502
in compartment: 890948
type: Species
initial amount: 0.0
has part: IPR002955
is: SBO:0000296

891266
fast: false
is version of: GO:0005914
type: Reaction
kinetic law: 044371
reactant: 044334
reversible: false
is: SBO:0000526
reactant: 044346
product: 044358

891276
is: SBO:0000526
product: 044780
reactant: 044768
reactant: 044756
type: Reaction
fast: false
product: 044792
is version of: GO:0016567
reversible: false
kinetic law: 044804

044141
stoichiometry: 1.0
species: 890978
type: SpeciesReference

044623
stoichiometry: 1.0
species: 890959
type: SpeciesReference

043983
stoichiometry: 1.0
species: 891061
type: SpeciesReference

044563
stoichiometry: 1.0
species: 890951
type: SpeciesReference

042584
stoichiometry: 1.0
species: 890990
type: SpeciesReference

041517
stoichiometry: 1.0
species: 890975
type: SpeciesReference

890959
is version of: P04637
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 890948
type: Species

891154
reversible: false
type: Reaction
product: 041979
reactant: 041967
is version of: GO:0016567
kinetic law: 042016
is: SBO:0000526
product: 042004
product: 041992
fast: false
reactant: 041955

043345
stoichiometry: 1.0
species: 891034
type: SpeciesReference

891267
is: SBO:0000183
fast: false
product: 044407
product: 044395
reactant: 044383
reversible: false
kinetic law: 044419
is part of: GO:0006351
type: Reaction

891217
product: 043249
is version of: GO:0016310
fast: false
reactant: 043237
type: Reaction
is: SBO:0000216
kinetic law: 043273
reversible: false
reactant: 043224
product: 043261

045019
stoichiometry: 1.0
species: 891013
type: SpeciesReference

042524
stoichiometry: 1.0
species: 890982
type: SpeciesReference

891277
reversible: false
is: SBO:0000526
reactant: 044828
kinetic law: 044863
product: 044839
type: Reaction
reactant: 044816
product: 044851
fast: false
is version of: GO:0016567

891163
is version of: GO:0009056
fast: false
is: SBO:0000179
reversible: false
reactant: 042149
kinetic law: 042185
product: 042161
type: Reaction
product: 042173

041627
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045092
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891214
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891121
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is version of: GO:0043241
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044935
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891142
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043381
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species: 891055
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044310
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042149
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891181
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891288
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type: Reaction
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044128
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species: 890994
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044214
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species: 891061
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045672
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species: 891067
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891064
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initial concentration: NaN
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type: Species
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890950
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891002
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species: 891019
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891160
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891097
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044732
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043321
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045080
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891226
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type: Reaction
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045478
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species: 891040
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043766
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042390
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species: 890992
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045165
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042801
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891082
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042245
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044947
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042560
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891130
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is version of: GO:0006461
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type: Reaction
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044226
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species: 891043
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042994
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species: 890950
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891076
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constant: true
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043128
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045612
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044671
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891145
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is version of: GO:0016567
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891070
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is: SBO:0000245
constant: false
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species: 891061
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species: 890996
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891061
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constant: false
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initial concentration: NaN
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890953
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constant: false
boundary condition: false
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891285
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891220
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is version of: GO:0016310
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042463
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891172
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type: Reaction
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reactant: 042306
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042716
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is: SBO:0000014
constant: false
boundary condition: false
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initial concentration: NaN
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891088
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041008
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044959
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891284
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is: SBO:0000526
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type: Reaction

042197
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891211
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type: Reaction

041930
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890954
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constant: false
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891271
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043092
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891298
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type: Reaction

044756
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891202
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045575
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045189
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891133
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reversible: false
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is version of: GO:0006461
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kinetic law: 041553
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044696
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043742
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043477
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type: SpeciesReference

040779
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scale: 0
multipler: 1.0
kind: ITEM
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044274
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043658
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boundary condition: false
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040875
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891184
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type: Reaction
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890994
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045660
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044768
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044395
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891007
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890952
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045588
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891296
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891223
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type: Reaction
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kinetic law: 043393

042269
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orgname: EMBL-EBI

n:
  given: Vijayalakshmi
  family: Chelliah

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler