463811
stoichiometry: 1.0
species: 801322
type: SpeciesReference

801509
constant: true
units: 462238
value: 0.144
type: Parameter

801588
constant: false
units: 462238
value: 0.0347
type: Parameter

801531
constant: true
units: 462141
value: 12.0
type: Parameter

464298
stoichiometry: 1.0
species: 801306
type: SpeciesReference

462178
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

801608
constant: true
units: 462008
value: 2.3
name: t_Apop_0.5
type: Parameter

463799
stoichiometry: 2.0
species: 801327
type: SpeciesReference

801497
constant: false
units: 462238
value: 0.0116
type: Parameter

462105
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

464833
stoichiometry: 1.0
species: 801303
type: SpeciesReference

801508
constant: true
units: 462141
value: 156.0
type: Parameter

801560
constant: true
units: 462141
value: 4.45
type: Parameter

462734
stoichiometry: 1.0
species: 801313
type: SpeciesReference

464591
stoichiometry: 1.0
species: 801324
type: SpeciesReference

801520
constant: true
units: 462141
value: 12.0
type: Parameter

801570
constant: true
units: 462141
value: 156.0
type: Parameter

801599
constant: false
units: 462238
value: 0.0058
type: Parameter

463135
stoichiometry: 1.0
species: 801313
type: SpeciesReference

801309
constant: false
name: XIAP-Casp9
has only substance units: false
type: Species
has part: P98170
initial concentration: 0.0
is: SBO:0000296
initial amount: NaN
boundary condition: false
in compartment: 801296
has part: P55211

801558
constant: true
units: 462190
value: 156.0
type: Parameter

463174
stoichiometry: 1.0
species: 801321
type: SpeciesReference

801561
constant: true
units: 462238
value: 31.9
type: Parameter

801548
constant: true
units: 462190
value: 420.0
type: Parameter

462924
stoichiometry: 1.0
species: 801319
type: SpeciesReference

462117
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

464845
stoichiometry: 1.0
species: 801328
type: SpeciesReference

464201
stoichiometry: 1.0
species: 801327
type: SpeciesReference

801499
constant: true
units: 462141
value: 6.0
type: Parameter

801572
constant: true
units: 462190
value: 420.0
type: Parameter

463546
stoichiometry: 1.0
species: 801306
type: SpeciesReference

462937
stoichiometry: 1.0
species: 801304
type: SpeciesReference

463787
stoichiometry: 1.0
species: 801300
type: SpeciesReference

801547
constant: true
units: 462238
value: 0.133
type: Parameter

801506
constant: true
units: 462238
value: 0.144
type: Parameter

801587
constant: true
units: 462238
value: 0.0347
type: Parameter

801619
constant: false
units: dimensionless
value: NaN
name: normalised Casp9-P
type: Parameter

801532
constant: true
units: 462141
value: 156.0
type: Parameter

801609
constant: true
units: 462008
value: 1.5
type: Parameter

462722
stoichiometry: 1.0
species: 801312
type: SpeciesReference

462819
stoichiometry: 1.0
species: 801300
type: SpeciesReference

801573
constant: true
units: 462238
value: 156.0
type: Parameter

463872
stoichiometry: 1.0
species: 801301
type: SpeciesReference

801409
kinetic law: 464627
reactant: 464615
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801594
constant: true
units: 462238
value: 0.0058
type: Parameter

463056
stoichiometry: 1.0
species: 801312
type: SpeciesReference

801525
constant: true
units: 462141
value: 12.0
type: Parameter

801535
constant: true
units: 462141
value: 156.0
type: Parameter

463161
stoichiometry: 1.0
species: 801316
type: SpeciesReference

801505
constant: true
units: 462141
value: 156.0
type: Parameter

464857
stoichiometry: 1.0
species: 801301
type: SpeciesReference

801564
constant: true
units: 462238
value: 14.2
type: Parameter

463835
stoichiometry: 1.0
species: 801309
type: SpeciesReference

464274
stoichiometry: 1.0
species: 801330
type: SpeciesReference

801408
kinetic law: 464603
reactant: 464591
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

464347
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801593
constant: false
units: 462238
value: 0.0347
type: Parameter

801348
is: SBO:0000526
reversible: true
product: 462686
fast: false
kinetic law: 462698
reactant: 462662
type: Reaction
is version of: GO:0006461
reactant: 462674

801545
constant: true
units: 462190
value: 420.0
type: Parameter

462335
stoichiometry: 1.0
species: 801299
type: SpeciesReference

801534
constant: true
units: 462238
value: 0.144
type: Parameter

801585
constant: true
units: 462238
value: 0.0058
type: Parameter

801388
kinetic law: 464310
reactant: 464298
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

462710
stoichiometry: 1.0
species: 801304
type: SpeciesReference

462528
stoichiometry: 1.0
species: 801306
type: SpeciesReference

463860
stoichiometry: 1.0
species: 801322
type: SpeciesReference

463239
stoichiometry: 1.0
species: 801316
type: SpeciesReference

801349
reversible: true
reactant: 462722
is: SBO:0000526
reactant: 462710
fast: false
is version of: GO:0006461
product: 462734
type: Reaction
kinetic law: 462746

801417
is version of: GO:0032403
is: SBO:0000344
type: Reaction
product: 464760
product: 464773
kinetic law: 464785
fast: false
reversible: true
reactant: 464748
reactant: 464736

801554
constant: true
units: 462141
value: 156.0
type: Parameter

463908
stoichiometry: 2.0
species: 801327
type: SpeciesReference

801575
constant: true
units: 462238
value: 0.0058
type: Parameter

801544
constant: true
value: 0.0
type: Parameter

801537
constant: true
units: 462238
value: 0.144
type: Parameter

801596
constant: false
units: 462238
value: 0.0347
type: Parameter

801523
constant: true
units: 462141
value: 12.0
type: Parameter

801503
constant: true
units: 462141
value: 2.4
type: Parameter

463763
stoichiometry: 1.0
species: 801300
type: SpeciesReference

463122
stoichiometry: 1.0
species: 801304
type: SpeciesReference

464262
stoichiometry: 2.0
species: 801327
type: SpeciesReference

801581
constant: false
units: 462238
value: 0.0347
type: Parameter

463847
stoichiometry: 2.0
species: 801327
type: SpeciesReference

801406
kinetic law: 464579
reactant: 464567
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801576
constant: true
units: 462238
value: 0.0058
type: Parameter

463043
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801597
constant: true
units: 462238
value: 0.0058
type: Parameter

801522
constant: true
units: 462141
value: 12.0
type: Parameter

801502
constant: true
units: 462141
value: 48.0
type: Parameter

462383
stoichiometry: 1.0
species: 801301
type: SpeciesReference

801583
constant: false
units: 462238
value: 0.0347
type: Parameter

801419
kinetic law: 464821
product: 464809
reactant: 464797
is version of: REACT 1101
is: SBO:0000185
fast: false
reversible: true
type: Reaction

801556
constant: true
units: 462190
value: 420.0
type: Parameter

801563
constant: true
units: 462141
value: 0.33
type: Parameter

464493
stoichiometry: 1.0
species: 801330
type: SpeciesReference

462008
unit: 462020
name: min
type: SBMLUnitsDef

462859
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801405
kinetic law: 464555
reactant: 464543
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801542
constant: true
value: 0.0
type: Parameter

801578
constant: true
units: 462238
value: 0.0058
type: Parameter

801541
constant: true
units: 462238
value: 0.144
type: Parameter

464419
stoichiometry: 1.0
species: 801309
type: SpeciesReference

462190
unit: 462226
unit: 462214
unit: 462202
name: 1/(uM^2*min)
type: SBMLUnitsDef

801358
product: 463174
type: Reaction
is: SBO:0000344
is version of: GO:0032403
kinetic law: 463187
product: 463161
product: 463148
reversible: true
fast: false
reactant: 463135
reactant: 463122

463425
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801378
is version of: REACT 1090
is: SBO:0000526
reactant: 463908
fast: false
reactant: 463896
kinetic law: 463945
product: 463920
is version of: GO:0032403
product: 463933
type: Reaction
reversible: true

801614
constant: false
units: dimensionless
value: NaN
name: XIAP2*SMAC per XIAP
type: Parameter

801600
constant: false
units: 462238
value: 0.0347
type: Parameter

464881
stoichiometry: 1.0
species: 801336
type: SpeciesReference

801364
product: 463461
is version of: GO:0032403
is: SBO:0000344
type: Reaction
reactant: 463425
fast: false
reversible: true
kinetic law: 463486
reactant: 463437
product: 463449
product: 463473

462782
stoichiometry: 1.0
species: 801316
type: SpeciesReference

W3 CDTF: Fri Jul 30 16:23:23 BST 2010

462395
stoichiometry: 1.0
species: 801299
type: SpeciesReference

801569
constant: true
units: 462141
value: 0.33
type: Parameter

801627
constant: false
units: dimensionless
value: NaN
name: percent SMAC release
type: Parameter

463002
stoichiometry: 1.0
species: 801316
type: SpeciesReference

801579
constant: false
units: 462238
value: 0.0347
type: Parameter

801345
type: Reaction
fast: false
kinetic law: 462600
is: SBO:0000344
is version of: GO:0016485
reversible: true
reactant: 462564
product: 462588
reactant: 462576

801550
constant: true
units: 462141
value: 156.0
type: Parameter

464518
stoichiometry: 1.0
species: 801322
type: SpeciesReference

464323
stoichiometry: 1.0
species: 801301
type: SpeciesReference

462911
stoichiometry: 1.0
species: 801315
type: SpeciesReference

462056
unit: 462081
unit: 462068
name: microM
type: SBMLUnitsDef

463364
stoichiometry: 1.0
species: 801310
type: SpeciesReference

801379
is version of: GO:0032403
product: 463982
reactant: 463957
is: SBO:0000526
kinetic law: 464018
product: 463994
type: Reaction
reactant: 463969
fast: false
reversible: true
product: 464006

463751
stoichiometry: 1.0
species: 801312
type: SpeciesReference

462444
stoichiometry: 1.0
species: 801301
type: SpeciesReference

801346
reversible: true
kinetic law: 462650
fast: false
reactant: 462625
is: SBO:0000526
product: 462638
is version of: GO:0006461
type: Reaction
reactant: 462612

801566
constant: true
units: 462141
value: 4.45
type: Parameter

464128
stoichiometry: 1.0
species: 801316
type: SpeciesReference

801376
type: Reaction
is version of: GO:0032403
product: 463872
reactant: 463847
kinetic law: 463884
reversible: true
reactant: 463835
is: SBO:0000526
product: 463860
is version of: REACT 1312
fast: false

801602
constant: true
units: 462238
value: 0.0058
type: Parameter

463401
stoichiometry: 1.0
species: 801313
type: SpeciesReference

464712
stoichiometry: 1.0
species: 801327
type: SpeciesReference

801612
constant: false
units: 462056
value: NaN
name: initial XIAP conc
type: Parameter

801366
kinetic law: 463558
product: 463534
is: SBO:0000344
reactant: 463510
type: Reaction
product: 463522
is version of: GO:0032403
fast: false
reactant: 463498
product: 463546
reversible: true

801629
constant: false
units: 462056
value: NaN
name: total SMAC
type: Parameter

462044
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

801552
constant: true
units: 462190
value: 420.0
type: Parameter

801567
constant: true
units: 462141
value: 156.0
type: Parameter

801357
fast: false
product: 463095
type: Reaction
kinetic law: 463108
is: SBO:0000344
reversible: true
product: 463069
is version of: GO:0032403
product: 463082
reactant: 463043
reactant: 463056

801639
constant: false
units: dimensionless
value: NaN
type: Parameter

463352
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801367
is version of: GO:0006461
reactant: 463570
reactant: 463582
type: Reaction
fast: false
reversible: true
kinetic law: 463606
is: SBO:0000344
product: 463594

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

801611
constant: false
units: dimensionless
value: NaN
name: free SMAC per XIAP
type: Parameter

801354
is: SBO:0000344
product: 462937
product: 462924
type: Reaction
fast: false
kinetic law: 462950
product: 462911
reactant: 462898
is version of: GO:0032403
reactant: 462885
reversible: true

462251
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

462758
stoichiometry: 1.0
species: 801304
type: SpeciesReference

463449
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801637
constant: false
units: dimensionless
value: NaN
type: Parameter

801355
product: 463002
is version of: GO:0032403
type: Reaction
kinetic law: 463029
product: 463016
fast: false
product: 462989
reversible: true
reactant: 462976
is: SBO:0000344
reactant: 462963

801623
constant: false
units: 462056
value: NaN
name: Caspase3 tot
type: Parameter

462468
stoichiometry: 1.0
species: 801306
type: SpeciesReference

801603
constant: true
units: 462141
value: 12.0
type: Parameter

462081
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

801340
product: 462419
kinetic law: 462431
fast: false
reactant: 462383
product: 462407
is: SBO:0000297
is version of: GO:0016485
reversible: true
reactant: 462395
type: Reaction

464213
stoichiometry: 1.0
species: 801325
type: SpeciesReference

801369
is version of: GO:0006461
kinetic law: 463654
reactant: 463618
type: Reaction
product: 463642
fast: false
reactant: 463630
reversible: true
is: SBO:0000344

462129
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

801617
constant: false
units: 462056
value: NaN
name: Caspase9 tot
type: Parameter

463690
stoichiometry: 1.0
species: 801319
type: SpeciesReference

801352
product: 462832
fast: false
type: Reaction
reactant: 462806
is: SBO:0000526
is version of: GO:0032403
kinetic law: 462872
product: 462845
reversible: true
product: 462859
reactant: 462819

801636
constant: false
units: dimensionless
value: NaN
type: Parameter

463896
stoichiometry: 1.0
species: 801307
type: SpeciesReference

463618
stoichiometry: 1.0
species: 801301
type: SpeciesReference

463082
stoichiometry: 1.0
species: 801315
type: SpeciesReference

801342
fast: false
reactant: 462456
is: SBO:0000231
kinetic law: 462492
reversible: true
product: 462480
is version of: GO:0016485
product: 462468
reactant: 462444
type: Reaction

801606
constant: false
units: 462056
value: NaN
name: limiting factor for apoptosome formation
type: Parameter

464736
stoichiometry: 1.0
species: 801304
type: SpeciesReference

462832
stoichiometry: 1.0
species: 801315
type: SpeciesReference

463437
stoichiometry: 1.0
species: 801309
type: SpeciesReference

464395
stoichiometry: 1.0
species: 801310
type: SpeciesReference

464226
stoichiometry: 1.0
species: 801301
type: SpeciesReference

801351
type: Reaction
product: 462782
kinetic law: 462794
is version of: GO:0006461
reactant: 462770
reactant: 462758
reversible: true
fast: false
is: SBO:0000526

462456
stoichiometry: 1.0
species: 801304
type: SpeciesReference

464543
stoichiometry: 1.0
species: 801315
type: SpeciesReference

801343
product: 462540
is version of: GO:0006461
reactant: 462504
is: SBO:0000231
fast: false
reversible: true
product: 462528
type: Reaction
kinetic law: 462552
reactant: 462516

464894
stoichiometry: 1.0
species: 801337
type: SpeciesReference

801625
constant: false
units: dimensionless
value: NaN
name: normalised Procasp-3
type: Parameter

463715
stoichiometry: 1.0
species: 801321
type: SpeciesReference

801605
constant: true
units: 462008
value: 7.0
name: t_SMAC_0.5
type: Parameter

462068
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

801615
constant: false
units: dimensionless
value: NaN
name: normalised Casp-9
type: Parameter

462845
stoichiometry: 1.0
species: 801318
type: SpeciesReference

462093
unit: 462129
unit: 462117
unit: 462105
name: uM/min
type: SBMLUnitsDef

464663
stoichiometry: 1.0
species: 801319
type: SpeciesReference

464567
stoichiometry: 1.0
species: 801318
type: SpeciesReference

801645
constant: false
units: dimensionless
value: NaN
type: Parameter

801631
constant: false
units: dimensionless
value: NaN
name: percent Apoptosome formation
type: Parameter

801370
reactant: 463678
fast: false
reversible: true
is version of: GO:0006461
is: SBO:0000344
product: 463690
kinetic law: 463702
type: Reaction
reactant: 463666

801649
constant: false
units: 462056
value: NaN
type: Parameter

801333
is: SBO:0000252
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 801296
name: Clevage Products
type: Species

463498
stoichiometry: 1.0
species: 801304
type: SpeciesReference

462612
stoichiometry: 1.0
species: 801304
type: SpeciesReference

462564
stoichiometry: 1.0
species: 801299
type: SpeciesReference

463582
stoichiometry: 1.0
species: 801300
type: SpeciesReference

463522
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801390
kinetic law: 464335
reactant: 464323
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801322
has only substance units: false
initial amount: NaN
initial concentration: 0.0
type: Species
boundary condition: false
in compartment: 801296
constant: false
has part: P98170
name: XIAP-2*SMAC
is: SBO:0000296

464031
stoichiometry: 1.0
species: 801315
type: SpeciesReference

801632
constant: false
units: dimensionless
value: NaN
type: Parameter

464104
stoichiometry: 1.0
species: 801325
type: SpeciesReference

801646
constant: true
units: 462056
value: 0.01
type: Parameter

462963
stoichiometry: 1.0
species: 801304
type: SpeciesReference

463148
stoichiometry: 1.0
species: 801304
type: SpeciesReference

463727
stoichiometry: 1.0
species: 801318
type: SpeciesReference

801643
constant: false
units: dimensionless
value: NaN
type: Parameter

801321
name: BIR3R-p2frag
initial concentration: 0.0
has only substance units: false
in compartment: 801296
is: SBO:0000296
boundary condition: false
is part of: P55211
is part of: P98170
initial amount: NaN
type: Species
constant: false

463095
stoichiometry: 1.0
species: 801321
type: SpeciesReference

BIOMD0000000256
reaction: 801420
species: 801333
area units: metaid_0000005
units def: 462238
name: Rehm2006_Caspase
reaction: 801409
reaction: 801400
reaction: 801375
parameter: 801645
parameter: 801503
parameter: 801541
reaction: 801417
compartment: 801296
rule: 801469
reaction: 801363
species: 801322
reaction: 801405
parameter: 801579
reaction: 801388
parameter: 801594
rule: 801485
parameter: 801606
parameter: 801621
species: 801327
parameter: 801614
parameter: 801526
occurs in: BTO:0000567
parameter: 801567
parameter: 801499
reaction: 801376
rule: 801480
rule: 801466
parameter: 801632
reaction: 801348
parameter: 801640
parameter: 801649
species: 801336
parameter: 801514
parameter: 801602
species: 801318
parameter: 801494
parameter: 801509
rule: 801478
reaction: 801364
parameter: 801570
parameter: 801512
reaction: 801352
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reaction: 801419
species: 801328
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parameter: 801493
species: 801312
rule: 801472
parameter: 801500
reaction: 801340
parameter: 801588
parameter: 801596
parameter: 801511
parameter: 801646
parameter: 801558
parameter: 801599
parameter: 801528
parameter: 801576
parameter: 801591
parameter: 801569
reaction: 801378
reaction: 801395
parameter: 801634
reaction: 801406
parameter: 801642
parameter: 801539
parameter: 801587
parameter: 801554
reaction: 801358
parameter: 801516
parameter: 801564
rule: 801471
reaction: 801366
parameter: 801572

463570
stoichiometry: 1.0
species: 801301
type: SpeciesReference

462576
stoichiometry: 1.0
species: 801304
type: SpeciesReference

463534
stoichiometry: 1.0
species: 801321
type: SpeciesReference

462662
stoichiometry: 1.0
species: 801304
type: SpeciesReference

462638
stoichiometry: 1.0
species: 801307
type: SpeciesReference

801420
has version: REACT 89
reactant: 464833
kinetic law: 464869
is version of: GO:0006461
product: 464857
type: Reaction
fast: false
reversible: true
is: SBO:0000526
reactant: 464845

801648
constant: false
units: 462056
value: NaN
type: Parameter

801634
constant: false
units: dimensionless
value: NaN
type: Parameter

464639
stoichiometry: 1.0
species: 801316
type: SpeciesReference

462989
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801334
name: SMAC in mitochondrium
type: Species
is version of: Q9NR28
initial concentration: 0.126
in compartment: 801298
has only substance units: false
is: SBO:0000245
constant: false
initial amount: NaN
boundary condition: false

801621
constant: false
units: dimensionless
value: NaN
name: normalised Casp-3
type: Parameter

462976
stoichiometry: 1.0
species: 801307
type: SpeciesReference

801375
reversible: true
kinetic law: 463823
fast: false
reactant: 463799
type: Reaction
is: SBO:0000526
is version of: GO:0006461
product: 463811
reactant: 463787

463376
stoichiometry: 1.0
species: 801304
type: SpeciesReference

464188
stoichiometry: 1.0
species: 801319
type: SpeciesReference

462625
stoichiometry: 1.0
species: 801300
type: SpeciesReference

463303
stoichiometry: 1.0
species: 801304
type: SpeciesReference

462020
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

801360
is: SBO:0000344
type: Reaction
product: 463226
reactant: 463213
product: 463252
product: 463239
reactant: 463200
fast: false
is version of: GO:0032403
kinetic law: 463265
reversible: true

463473
stoichiometry: 1.0
species: 801312
type: SpeciesReference

464773
stoichiometry: 1.0
species: 801333
type: SpeciesReference

462770
stoichiometry: 1.0
species: 801315
type: SpeciesReference

463933
stoichiometry: 1.0
species: 801304
type: SpeciesReference

464371
stoichiometry: 1.0
species: 801307
type: SpeciesReference

464688
stoichiometry: 1.0
species: 801321
type: SpeciesReference

801373
kinetic law: 463775
product: 463763
reactant: 463751
is version of: GO:0043241
is: SBO:0000180
fast: false
reversible: true
type: Reaction

462674
stoichiometry: 1.0
species: 801309
type: SpeciesReference

801642
constant: false
units: dimensionless
value: NaN
type: Parameter

462588
stoichiometry: 2.0
species: 801304
type: SpeciesReference

801363
is: SBO:0000344
product: 463376
reactant: 463364
reversible: true
product: 463389
fast: false
reactant: 463352
type: Reaction
is version of: GO:0032403
product: 463401
kinetic law: 463413

462359
stoichiometry: 1.0
species: 801300
type: SpeciesReference

801331
constant: false
boundary condition: false
has only substance units: false
is part of: P42574
initial concentration: 1.0
is: SBO:0000252
initial amount: NaN
type: Species
name: Casp3 Substrate
in compartment: 801296

463920
stoichiometry: 1.0
species: 801322
type: SpeciesReference

801372
kinetic law: 463739
product: 463727
reactant: 463715
is version of: GO:0043241
is: SBO:0000180
fast: false
reversible: true
type: Reaction

463461
stoichiometry: 1.0
species: 801306
type: SpeciesReference

463315
stoichiometry: 1.0
species: 801324
type: SpeciesReference

462032
unit: 462044
name: micromole
type: SBMLUnitsDef

463389
stoichiometry: 1.0
species: 801306
type: SpeciesReference

801310
initial concentration: 0.0
type: Species
is: SBO:0000296
has part: P42574
name: XIAP-Casp9-Casp3
has part: P55211
in compartment: 801296
boundary condition: false
constant: false
has part: P98170
has only substance units: false
initial amount: NaN

464615
stoichiometry: 1.0
species: 801325
type: SpeciesReference

801330
type: Species
has part: Q9NR28
name: XIAP-p2frag-2*SMAC
constant: false
has only substance units: false
initial concentration: 0.0
in compartment: 801296
is part of: P55211
is: SBO:0000296
boundary condition: false
initial amount: NaN
has part: P98170

463510
stoichiometry: 1.0
species: 801319
type: SpeciesReference

464760
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801361
product: 463303
reactant: 463291
reactant: 463278
reversible: true
kinetic law: 463340
fast: false
is: SBO:0000344
type: Reaction
product: 463315
is version of: GO:0032403
product: 463327

801640
constant: false
units: dimensionless
value: NaN
type: Parameter

462686
stoichiometry: 1.0
species: 801310
type: SpeciesReference

801590
constant: false
units: 462238
value: 0.0347
type: Parameter

463213
stoichiometry: 1.0
species: 801310
type: SpeciesReference

463666
stoichiometry: 1.0
species: 801301
type: SpeciesReference

464918
persistant: true
initial value: true
type: Trigger

801313
initial amount: NaN
name: XIAP-p2frag-Casp3
is: SBO:0000296
constant: false
is part of: P55211
has only substance units: false
boundary condition: false
type: Species
initial concentration: 0.0
has part: P98170
has part: P42574
in compartment: 801296

464444
stoichiometry: 1.0
species: 801312
type: SpeciesReference

462238
unit: 462251
name: 1/min
type: SBMLUnitsDef

464079
stoichiometry: 1.0
species: 801318
type: SpeciesReference

462898
stoichiometry: 1.0
species: 801309
type: SpeciesReference

801516
constant: true
units: 462238
value: 0.144
type: Parameter

463957
stoichiometry: 1.0
species: 801310
type: SpeciesReference

462516
stoichiometry: 1.0
species: 801299
type: SpeciesReference

801398
kinetic law: 464457
reactant: 464444
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801526
constant: true
units: 462141
value: 12.0
type: Parameter

801303
is version of: P55211
name: ProCasp9
in compartment: 801296
boundary condition: false
type: Species
has only substance units: false
is: SBO:0000245
initial concentration: 0.03
initial amount: NaN
constant: false

801512
constant: true
units: 462238
value: 0.144
type: Parameter

801416
kinetic law: 464724
reactant: 464712
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

462806
stoichiometry: 1.0
species: 801304
type: SpeciesReference

464797
stoichiometry: 1.0
species: 801334
type: SpeciesReference

801384
reversible: true
product: 464152
product: 464164
has version: REACT 1090
reactant: 464128
kinetic law: 464176
fast: false
type: Reaction
reactant: 464140
is: SBO:0000526
is version of: GO:0032403

463678
stoichiometry: 1.0
species: 801318
type: SpeciesReference

801312
name: XIAP-p2 fragment
boundary condition: false
has part: P98170
initial amount: NaN
initial concentration: 0.0
is: SBO:0000296
constant: false
is part of: P55211
has only substance units: false
in compartment: 801296
type: Species

464164
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801385
kinetic law: 464238
product: 464226
reactant: 464201
product: 464213
reversible: true
fast: false
type: Reaction
has version: REACT 1312
reactant: 464188
is: SBO:0000526
is version of: GO:0032403

801517
constant: true
units: 462141
value: 12.0
type: Parameter

463200
stoichiometry: 1.0
species: 801304
type: SpeciesReference

463327
stoichiometry: 1.0
species: 801325
type: SpeciesReference

463278
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801395
kinetic law: 464407
reactant: 464395
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

462419
stoichiometry: 1.0
species: 801301
type: SpeciesReference

462141
unit: 462178
unit: 462166
unit: 462154
name: 1/(uM*min)
type: SBMLUnitsDef

462480
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801514
constant: true
units: 462141
value: 156.0
type: Parameter

801500
constant: true
units: 462141
value: 12.0
type: Parameter

801315
is part of: P98170
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 801296
type: Species

801301
is version of: P55211
in compartment: 801296
constant: false
boundary condition: false
has only substance units: false
type: Species
is: SBO:0000245
initial concentration: 0.0
name: Casp9(p35-p12)
initial amount: NaN

801528
constant: true
units: 462141
value: 12.0
type: Parameter

462504
stoichiometry: 1.0
species: 801306
type: SpeciesReference

801591
constant: true
units: 462238
value: 0.0058
type: Parameter

801414
kinetic law: 464700
reactant: 464688
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801328
is version of: O14727
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.372
initial amount: NaN
in compartment: 801296
type: Species

801299
initial concentration: 0.12
boundary condition: false
type: Species
name: ProCasp3
in compartment: 801296
is version of: P42574
has only substance units: false
initial amount: NaN
constant: false
is: SBO:0000245

463226
stoichiometry: 1.0
species: 801304
type: SpeciesReference

463016
stoichiometry: 1.0
species: 801318
type: SpeciesReference

463252
stoichiometry: 1.0
species: 801319
type: SpeciesReference

464092
stoichiometry: 1.0
species: 801327
type: SpeciesReference

801387
type: Reaction
product: 464274
fast: false
reversible: true
has version: REACT 1090
kinetic law: 464286
reactant: 464262
is version of: GO:0006461
reactant: 464250
is: SBO:0000526

464152
stoichiometry: 1.0
species: 801324
type: SpeciesReference

801511
constant: true
units: 462141
value: 156.0
type: Parameter

463291
stoichiometry: 1.0
species: 801322
type: SpeciesReference

801529
constant: true
units: 462141
value: 12.0
type: Parameter

801397
kinetic law: 464431
reactant: 464419
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801300
is version of: P98170
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.063
initial amount: NaN
in compartment: 801296
type: Species

801400
kinetic law: 464481
reactant: 464469
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801337
type: Species
is: SBO:0000245
has only substance units: false
initial concentration: 0.0
in compartment: 801296
constant: false
initial amount: NaN
boundary condition: false
is version of: P08574
name: cytosolic Cytochrome C

801298
is version of: GO:0005739
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0
name: mitochondrium
type: Compartment

801327
is version of: Q9NR28
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 801296
type: Species

801411
kinetic law: 464651
reactant: 464639
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

464055
stoichiometry: 1.0
species: 801324
type: SpeciesReference

801393
kinetic law: 464383
reactant: 464371
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801493
constant: false
units: 462093
value: 4.68E-4
type: Parameter

801307
initial concentration: 0.0
is: SBO:0000296
constant: false
has part: P42574
has only substance units: false
boundary condition: false
initial amount: NaN
name: XIAP-Casp3
type: Species
in compartment: 801296
has part: P98170

463642
stoichiometry: 1.0
species: 801310
type: SpeciesReference

462540
stoichiometry: 1.0
species: 801304
type: SpeciesReference

462214
exponent: 2.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

462407
stoichiometry: 1.0
species: 801304
type: SpeciesReference

464006
stoichiometry: 1.0
species: 801301
type: SpeciesReference

464140
stoichiometry: 1.0
species: 801327
type: SpeciesReference

801336
initial concentration: 10.0
type: Species
is: SBO:0000245
has only substance units: false
boundary condition: false
is version of: P08574
constant: false
name: Cytochrome C in mitochondrium
in compartment: 801298
initial amount: NaN

801412
kinetic law: 464675
reactant: 464663
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801422
kinetic law: 464906
product: 464894
reactant: 464881
is version of: REACT 535
is: SBO:0000185
fast: false
reversible: true
type: Reaction

801402
kinetic law: 464506
reactant: 464493
is part of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

462166
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

463994
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801316
boundary condition: false
in compartment: 801296
has only substance units: false
name: BIR12-Casp3
initial concentration: 0.0
is: SBO:0000296
constant: false
has part: P42574
initial amount: NaN
type: Species
is part of: P98170

801306
constant: false
initial concentration: 0.0
initial amount: NaN
has part: P55211
boundary condition: false
type: Species
name: Casp9(p35-p10)
in compartment: 801296
is: SBO:0000245
has only substance units: false

462202
exponent: -2.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

801296
is: GO:0005623
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0
type: Compartment

464043
stoichiometry: 1.0
species: 801327
type: SpeciesReference

801381
type: Reaction
reversible: true
is version of: GO:0006461
product: 464055
fast: false
reactant: 464043
reactant: 464031
is: SBO:0000526
kinetic law: 464067

463969
stoichiometry: 2.0
species: 801327
type: SpeciesReference

801496
constant: false
units: 462093
value: 7.308E-4
type: Parameter

801325
type: Species
has only substance units: false
is part of: P98170
is: SBO:0000296
constant: false
initial concentration: 0.0
initial amount: NaN
name: BIR3R-SMAC
in compartment: 801296
boundary condition: false
has part: Q9NR28

801339
kinetic law: 462371
product: 462359
is: SBO:0000393
fast: false
reversible: true
name: XIAP Production
type: Reaction

464809
stoichiometry: 1.0
species: 801327
type: SpeciesReference

801391
kinetic law: 464359
reactant: 464347
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

801319
has part: P55211
is part of: P98170
is: SBO:0000296
constant: false
has only substance units: false
boundary condition: false
initial amount: NaN
type: Species
in compartment: 801296
initial concentration: 0.0
name: BIR3R-Casp9

463630
stoichiometry: 1.0
species: 801307
type: SpeciesReference

462226
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

801403
kinetic law: 464530
reactant: 464518
is version of: GO:0009056
is: SBO:0000179
fast: false
reversible: true
type: Reaction

463594
stoichiometry: 1.0
species: 801309
type: SpeciesReference

463069
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801539
constant: true
units: 462141
value: 156.0
type: Parameter

464469
stoichiometry: 1.0
species: 801313
type: SpeciesReference

464748
stoichiometry: 1.0
species: 801331
type: SpeciesReference

801382
reactant: 464079
product: 464104
kinetic law: 464116
is version of: GO:0006461
fast: false
type: Reaction
reactant: 464092
is: SBO:0000526
reversible: true

801324
has part: Q9NR28
is: SBO:0000296
constant: false
initial amount: NaN
is part of: P98170
initial concentration: 0.0
in compartment: 801296
name: BIR12-SMAC
has only substance units: false
boundary condition: false
type: Species

801338
kinetic law: 462347
product: 462335
is: SBO:0000393
fast: false
reversible: true
name: ProCaspase3 Production
type: Reaction

464250
stoichiometry: 1.0
species: 801312
type: SpeciesReference

462885
stoichiometry: 1.0
species: 801304
type: SpeciesReference

801318
is part of: P98170
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 801296
type: Species

801304
is version of: P42574
is: SBO:0000245
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 801296
type: Species

801494
constant: false
units: 462238
value: 0.0039
type: Parameter

462154
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

801463
event assignment: 464966
event assignment: 464942
event assignment: 465028
event assignment: 465015
event assignment: 465064
event assignment: 465052
type: Event
event assignment: 464930
event assignment: 465003
event assignment: 464979
event assignment: 464954
event assignment: 464991
event assignment: 465076
event assignment: 465040
use values from trigger time: true
trigger: 464918

463982
stoichiometry: 1.0
species: 801322
type: SpeciesReference

801519
constant: true
units: 462141
value: 12.0
type: Parameter

W3 CDTF: Wed May 16 15:44:17 BST 2012