245471
value: 1.08E-6
type: LocalParameter

549056
stoichiometry: 1.0
species: metaid Mal
type: SpeciesReference

245261
value: 5.4E-6
type: LocalParameter

245060
value: 3.0E-5
type: LocalParameter

548684
stoichiometry: 1.0
species: metaid CO2
type: SpeciesReference

549466
stoichiometry: 1.0
species: metaid H2O
type: SpeciesReference

244767
kinetic law: 548189
product: 548177
fast: false
reversible: true
type: Reaction

245120
value: 0.0016
type: LocalParameter

245574
value: 3.7E-7
type: LocalParameter

metaid FAD
is: C00016
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00101
initial amount: NaN
in compartment: metaid MATRIX
name: FAD
type: Species

549562
stoichiometry: 1.0
species: metaid OXA cyt
type: SpeciesReference

245501
value: 0.00163
type: LocalParameter

550163
stoichiometry: 1.0
species: metaid Mal
type: SpeciesReference

245498
value: 3.3211E-5
type: LocalParameter

244803
kinetic law: 548610
product: 548598
reactant: 548586
reactant: 548574
is version of: GO:0004017
fast: false
reversible: true
type: Reaction

244980
value: 2.5E-5
type: LocalParameter

549647
stoichiometry: 1.0
species: metaid Cit cyt
type: SpeciesReference

548261
stoichiometry: 1.0
species: metaid ATP cyt
type: SpeciesReference

245174
value: 1.0E-4
type: LocalParameter

244970
value: 3.0E-4
type: LocalParameter

548900
stoichiometry: 1.0
species: metaid SCoA
type: SpeciesReference

550067
stoichiometry: 1.0
species: metaid Mal cyt
type: SpeciesReference

244893
type: Reaction
product: 549526
name: oxoglutarate carrier
reactant: 549502
reversible: true
reactant: 549514
fast: false
is version of: GO:0015367
product: 549538
kinetic law: metaid kineticLaw v30

548429
stoichiometry: 1.0
species: metaid DPG
type: SpeciesReference

245573
value: 0.066
type: LocalParameter

550019
stoichiometry: 1.0
species: metaid NADPH cyt
type: SpeciesReference

245499
value: 1.1E-4
type: LocalParameter

549707
stoichiometry: 1.0
species: metaid Q
type: SpeciesReference

548622
stoichiometry: 1.0
species: metaid PYR cyt
type: SpeciesReference

548816
stoichiometry: 1.0
species: metaid OG
type: SpeciesReference

245609
value: 3.5
type: LocalParameter

245522
value: 0.0016
type: LocalParameter

549995
stoichiometry: 1.0
species: metaid NADP cyt
type: SpeciesReference

548201
stoichiometry: 1.0
species: metaid LAC
type: SpeciesReference

metaid ADP cyt
is: C0008
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.08367E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: adenine diphosphate
type: Species

245288
value: 5.0E-6
type: LocalParameter

245489
value: 8.99
type: LocalParameter

metaid Q
is: CHEBI:16389
in compartment: metaid MT IMS
initial concentration: 0.026
is: C00399
constant: false
boundary condition: false
type: Species
initial amount: NaN
name: ubiquinone
has only substance units: false

245075
value: 3.8617E-7
name: SCS
type: LocalParameter

548696
stoichiometry: 1.0
species: metaid Acetyl CoA
type: SpeciesReference

metaid NADH cyt
is: C00004
initial amount: NaN
in compartment: metaid CYTOPLASM
is: CHEBI:16908
initial concentration: 6.16118E-4
constant: false
type: Species
has only substance units: false
boundary condition: false
name: NADH

245486
value: 1.19E-5
type: LocalParameter

550175
stoichiometry: 1.0
species: metaid NADP p
type: SpeciesReference

549550
stoichiometry: 1.0
species: metaid NADH cyt
type: SpeciesReference

metaid v39
reactant: 550127
is: http://identifiers.org/ec-code/1.1.1.40
product: 550151
reversible: true
product: 550139
kinetic law: metaid kineticLaw v39
type: Reaction
reactant: 550115
name: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
fast: false

metaid Asp
is: C00049
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00114
initial amount: NaN
in compartment: metaid MATRIX
name: aspartate
type: Species

245273
value: 622.1
type: LocalParameter

549044
stoichiometry: 1.0
species: metaid Fum
type: SpeciesReference

549478
stoichiometry: 1.0
species: metaid Cit cyt
type: SpeciesReference

245172
value: 9.0E-4
type: LocalParameter

548273
stoichiometry: 1.0
species: metaid F6P
type: SpeciesReference

548912
stoichiometry: 1.0
species: metaid NADH
type: SpeciesReference

244982
value: 1.3E-5
type: LocalParameter

245162
value: 0.69
type: LocalParameter

245076
value: 3.0E-5
type: LocalParameter

548635
stoichiometry: 1.0
species: metaid Pyr
type: SpeciesReference

549659
stoichiometry: 1.0
species: metaid Mal
type: SpeciesReference

245510
value: 2.4E-4
type: LocalParameter

245585
value: 1.3E-10
type: LocalParameter

metaid Acetyl CoA
is: C00024
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.0E-5
initial amount: NaN
in compartment: metaid MATRIX
name: acetyl CoA
type: Species

549719
stoichiometry: 1.0
species: metaid ETFox
type: SpeciesReference

550055
stoichiometry: 1.0
species: metaid Mal
type: SpeciesReference

245171
value: 3.8617E-7
name: AlaTA
type: LocalParameter

245087
value: 4.1E-6
type: LocalParameter

548996
stoichiometry: 1.0
species: metaid Suc
type: SpeciesReference

244804
kinetic law: metaid kineticLaw v8
product: 548635
reactant: 548622
is version of: GO:0005477
fast: false
reversible: true
name: pyruvate carrier
type: Reaction

548828
stoichiometry: 1.0
species: metaid NADH
type: SpeciesReference

245279
value: 9.963E-9
name: Complex_III
type: LocalParameter

549623
stoichiometry: 1.0
species: metaid OXA cyt
type: SpeciesReference

metaid NAD
in compartment: metaid CYTOPLASM
boundary condition: false
is: CHEBI:15846
is: C00003
name: NAD
has only substance units: false
initial concentration: 0.00362057
initial amount: NaN
constant: false
type: Species

245150
value: 0.032
type: LocalParameter

metaid v20
reversible: true
reactant: 549117
name: alanine transaminase
product: 549153
reactant: 549129
type: Reaction
is: http://identifiers.org/ec-code/2.6.1.2
fast: false
kinetic law: metaid kineticLaw v20
product: 549141

245216
value: 1.0
type: LocalParameter

549369
stoichiometry: 1.0
species: metaid Cytc3p
type: SpeciesReference

548177
stoichiometry: 1.0
species: metaid GLC
type: SpeciesReference

metaid v10
product: 548744
reactant: 548720
fast: false
kinetic law: metaid kineticLaw v10
reversible: true
name: citrate synthase
product: 548756
is: http://identifiers.org/ec-code/2.3.3.1
type: Reaction
reactant: 548732
is: http://identifiers.org/ec-code/2.3.3.3

metaid v37
kinetic law: metaid kineticLaw v37
is: http://identifiers.org/ec-code/1.1.99.5
reversible: false
product: 549887
fast: false
name: glycerol-3-phosphate dehydrogenase (FAD dependent)
type: Reaction
product: 549899
reactant: 549875
reactant: 549863

245624
value: 3.3211E-4
name: CIC
type: LocalParameter

245285
value: 0.002325
name: Complex_IV
type: LocalParameter

245588
value: 9.4E-8
type: LocalParameter

244770
kinetic law: 548237
reactant: 548225
fast: false
reversible: false
type: Reaction

548924
stoichiometry: 1.0
species: metaid GDP
type: SpeciesReference

245084
value: 1.5E-6
type: LocalParameter

245525
value: 1.3E-4
type: LocalParameter

550187
stoichiometry: 1.0
species: metaid NADPH
type: SpeciesReference

550115
stoichiometry: 1.0
species: metaid Mal cyt
type: SpeciesReference

245051
value: 8.375
type: LocalParameter

metaid DPG
is: C00236
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.99109E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: 1,2-bisphospho-D-glycerate
type: Species

549971
stoichiometry: 1.0
species: metaid ADP
type: SpeciesReference

245300
value: 4.5E-6
type: LocalParameter

548225
stoichiometry: 1.0
species: metaid GAP
type: SpeciesReference

245264
value: 5.7E-6
type: LocalParameter

245207
value: 0.0028
type: LocalParameter

metaid v38
reactant: 549911
reactant: 549923
type: Reaction
reversible: false
kinetic law: metaid kineticLaw v38
fast: false
name: glycerol-3-phosphate dehydrogenase (NAD+ dependent)
is: http://identifiers.org/ec-code/1.1.1.8
product: 549947
product: 549935

550043
stoichiometry: 1.0
species: metaid IsoCitcyt
type: SpeciesReference

245625
value: 1.11667
type: LocalParameter

245597
value: 4.4E-4
type: LocalParameter

245639
value: 3.8617E-7
name: MDH
type: LocalParameter

245576
value: 2.9E-5
type: LocalParameter

metaid OXA cyt
is: C00036
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0E-6
initial amount: NaN
in compartment: metaid CYTOPLASM
name: oxaloacetate
type: Species

244769
kinetic law: 548213
reactant: 548201
fast: false
reversible: false
type: Reaction

245267
value: 2.8E-6
type: LocalParameter

metaid v35
reactant: 549743
product: 549779
name: glutathione reductase
kinetic law: metaid kineticLaw v35
is: http://identifiers.org/ec-code/1.8.1.7
fast: false
reversible: true
reactant: 549755
type: Reaction
product: 549767

549635
stoichiometry: 1.0
species: metaid Glu cyt
type: SpeciesReference

549357
stoichiometry: 1.0
species: metaid Cytc2p
type: SpeciesReference

245204
value: 1.8E-4
type: LocalParameter

549454
stoichiometry: 1.0
species: metaid ATP
type: SpeciesReference

550199
stoichiometry: 1.0
species: metaid Pyr
type: SpeciesReference

245513
value: 5.1E-5
type: LocalParameter

245297
value: 5.0E-6
type: LocalParameter

549068
stoichiometry: 1.0
species: metaid Mal
type: SpeciesReference

548936
stoichiometry: 1.0
species: metaid SCoA
type: SpeciesReference

245636
value: 0.011
type: LocalParameter

245072
value: 100.0
type: LocalParameter

metaid Glu
is: C00025
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00303
initial amount: NaN
in compartment: metaid MATRIX
name: glutamate
type: Species

549983
stoichiometry: 1.0
species: metaid IsoCitcyt
type: SpeciesReference

metaid MATRIX
is: GO:0005759
constant: true
size: 1.0
spatial dimensions: 3.0
name: mitochondrial matrix
type: Compartment

metaid v21
fast: false
kinetic law: metaid kineticLaw v21
product: 549201
type: Reaction
product: 549189
is: http://identifiers.org/ec-code/2.6.1.1
reactant: 549177
reactant: 549165
reversible: true
name: aspartate transaminase

245276
value: 426.8
type: LocalParameter

245219
value: 1.0
type: LocalParameter

245063
value: 0.07
type: LocalParameter

metaid ATP cyt
is: C0002
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00449064
initial amount: NaN
in compartment: metaid CYTOPLASM
name: adenine triphosphate
type: Species

550103
stoichiometry: 1.0
species: metaid ATP cyt
type: SpeciesReference

metaid v36
reactant: 549815
reactant: 549803
reversible: true
reactant: 549791
is: http://identifiers.org/ec-code/6.4.1.1
product: 549839
type: Reaction
product: 549851
product: 549827
name: pyruvate decarboxylase
fast: false
kinetic law: metaid kineticLaw v36

metaid NADPH cyt
is: CHEBI:16474
initial amount: NaN
is: C00005
boundary condition: false
initial concentration: 6.16118E-4
type: Species
constant: false
has only substance units: false
name: NADPH
in compartment: metaid CYTOPLASM

550007
stoichiometry: 1.0
species: metaid OG cyt
type: SpeciesReference

245627
value: 0.005
type: LocalParameter

245286
value: 0.004833
type: LocalParameter

245073
value: 100.0
type: LocalParameter

245595
value: 1.3E-4
type: LocalParameter

549441
stoichiometry: 1.0
species: metaid Pi
type: SpeciesReference

548309
stoichiometry: 1.0
species: metaid ATP cyt
type: SpeciesReference

245441
value: 3.9E-7
type: LocalParameter

245390
value: 4.0E-5
type: LocalParameter

245594
value: 3.8617E-7
name: IDHc
type: LocalParameter

metaid Mal
is: C00149
constant: false
boundary condition: false
has only substance units: false
initial concentration: 5.0E-4
initial amount: NaN
in compartment: metaid MATRIX
name: malate
type: Species

549189
stoichiometry: 1.0
species: metaid Asp
type: SpeciesReference

245640
value: 130.5
type: LocalParameter

549827
stoichiometry: 1.0
species: metaid Pi
type: SpeciesReference

549599
stoichiometry: 1.0
species: metaid Asp cyt
type: SpeciesReference

245315
value: 0.047
type: LocalParameter

244978
value: 3.3211E-4
name: PYC
type: LocalParameter

metaid v24
reactant: 549261
fast: false
reactant: 549273
is: http://identifiers.org/ec-code/2.7.4.6
type: Reaction
name: NADH:ubiquinone oxidoreductase
product: 549297
reversible: true
kinetic law: metaid kineticLaw v24
product: 549285

548333
stoichiometry: 1.0
species: metaid ADP cyt
type: SpeciesReference

metaid v4
product: 548405
kinetic law: metaid kineticLaw v4
type: Reaction
reversible: false
reactant: 548381
reactant: 548393
name: glyceraldehyde 3-phosphate dehydrogenase
product: 548417
is: http://identifiers.org/ec-code/1.2.1.12
fast: false

550139
stoichiometry: 1.0
species: metaid NADPH cyt
type: SpeciesReference

245480
value: 2.4E-7
type: LocalParameter

245556
value: 0.1667
type: LocalParameter

549514
stoichiometry: 1.0
species: metaid OG
type: SpeciesReference

548249
stoichiometry: 1.0
species: metaid GLC
type: SpeciesReference

244960
value: 0.05
type: LocalParameter

metaid v14
is: http://identifiers.org/ec-code/1.2.4.2
product: 548888
reversible: false
name: oxoglutarate dehydrogenase complex
kinetic law: metaid kineticLaw v14
reactant: 548876
product: 548912
product: 548900
type: Reaction
reactant: 548864
reactant: 548852
fast: false

244988
value: 3.0E-4
type: LocalParameter

548960
stoichiometry: 1.0
species: metaid Suc
type: SpeciesReference

548562
stoichiometry: 1.0
species: metaid NAD
type: SpeciesReference

245180
value: 0.004
type: LocalParameter

245468
value: 1.2E-7
type: LocalParameter

245549
value: 0.001
name: Glycerol-3-phosphate dehydrogenase
type: LocalParameter

245393
value: 0.004
type: LocalParameter

245450
value: 3.1E-7
type: LocalParameter

245621
value: 1.0
type: LocalParameter

245081
value: 3.0E-7
type: LocalParameter

245516
value: 9.0
type: LocalParameter

245117
value: 1.1E-4
type: LocalParameter

metaid v3
kinetic law: metaid kineticLaw v3
product: 548369
reactant: 548357
is: http://identifiers.org/ec-code/4.1.2.13
fast: false
reversible: true
name: fructose-bisphosphate aldolase
type: Reaction

metaid Asp cyt
is: C00049
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00114
initial amount: NaN
in compartment: metaid CYTOPLASM
name: aspartate
type: Species

548393
stoichiometry: 1.0
species: metaid NAD
type: SpeciesReference

metaid OG
is: C00026
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.1E-5
initial amount: NaN
in compartment: metaid MATRIX
name: oxoglutarate
type: Species

metaid v44
kinetic law: metaid kineticLaw v44
type: Reaction
reversible: true
reactant: 550163
name: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
product: 550187
is: http://identifiers.org/ec-code/1.1.1.40
product: 550199
fast: false
reactant: 550175

245555
value: 0.001
name: Glycerol-3-phosphate dehydrogenase
type: LocalParameter

metaid v34
product: 549731
product: 549719
is: http://identifiers.org/ec-code/1.5.5.1
fast: false
name: ETF:Q oxidoreductase
type: Reaction
reactant: 549707
reactant: 549695
reversible: true
kinetic law: metaid kineticLaw v34

244987
value: 5.5E-4
type: LocalParameter

245040
value: 5.0E-6
type: LocalParameter

245102
value: 9.9211E-5
name: SDH
type: LocalParameter

549177
stoichiometry: 1.0
species: metaid Glu
type: SpeciesReference

244962
value: 0.01
type: LocalParameter

549839
stoichiometry: 1.0
species: metaid ADP
type: SpeciesReference

metaid ADP
is: C0008
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.5E-4
initial amount: NaN
in compartment: metaid MATRIX
name: adenine diphosphate
type: Species

245453
value: 3.0E-7
type: LocalParameter

245642
value: 0.01295
type: LocalParameter

245396
value: 0.002
type: LocalParameter

metaid LAC
is: C00186
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.3981E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: lactate
type: Species

metaid v12
modifier: 548840
kinetic law: metaid kineticLaw v12
product: 548828
name: isocitrate dehydrogenase (NAD+) (alpha/beta/gamma)
fast: false
reactant: 548792
reversible: false
product: 548816
is: http://identifiers.org/ec-code/1.1.1.41
reactant: 548804
type: Reaction

metaid v26
kinetic law: metaid kineticLaw v26
product: 549369
reactant: 549357
is: http://identifiers.org/ec-code/1.9.3.1
fast: false
reversible: false
name: cytochrome c oxidase
type: Reaction

549526
stoichiometry: 1.0
species: metaid OG cyt
type: SpeciesReference

244976
value: 1.5E-7
type: LocalParameter

metaid v2
product: 548333
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.11
name: 6-phosphofructokinase
reversible: false
fast: false
reactant: 548297
kinetic law: metaid kineticLaw v2
modifier: 548345
product: 548321
reactant: 548309

245229
value: 9.2E-6
type: LocalParameter

245327
value: 31.44
type: LocalParameter

245507
value: 0.016
type: LocalParameter

245558
value: 0.012
type: LocalParameter

metaid H2O
is: C00001
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.001
initial amount: NaN
in compartment: metaid MATRIX
name: water
type: Species

550127
stoichiometry: 1.0
species: metaid NADP cyt
type: SpeciesReference

245492
value: 2.18
type: LocalParameter

metaid v31
reversible: false
reactant: 549550
product: 549587
fast: false
name: malate dehydrogenase (cytosol)
product: 549574
is: http://identifiers.org/ec-code/1.1.1.37
reactant: 549562
kinetic law: metaid kineticLaw v31
type: Reaction

245537
value: 200.0
type: LocalParameter

245591
value: 4.6E-14
type: LocalParameter

245633
value: 1.25E-4
type: LocalParameter

245129
value: 1.0E-4
type: LocalParameter

245528
value: 0.0079
type: LocalParameter

548550
stoichiometry: 1.0
species: metaid LAC
type: SpeciesReference

245192
value: 300.0
type: LocalParameter

245115
value: 7.2E-5
type: LocalParameter

549490
stoichiometry: 1.0
species: metaid IsoCitcyt
type: SpeciesReference

245567
value: 9.6E-7
type: LocalParameter

548501
stoichiometry: 1.0
species: metaid PYR cyt
type: SpeciesReference

244975
value: 1.0E-8
type: LocalParameter

metaid v25
is: http://identifiers.org/ec-code/1.10.2.2
product: 549345
type: Reaction
product: 549333
kinetic law: metaid kineticLaw v25
reactant: 549309
fast: false
reactant: 549321
name: ubiquinol:cytochrome c oxidoreductase
reversible: false

metaid v1
product: 548285
reactant: 548249
product: 548273
type: Reaction
name: glucokinase
reversible: false
kinetic law: metaid kineticLaw v1
reactant: 548261
fast: false
is: http://identifiers.org/ec-code/2.7.1.2

549249
stoichiometry: 1.0
species: metaid Glu
type: SpeciesReference

metaid v11
kinetic law: metaid kineticLaw v11
product: 548780
reactant: 548768
is: http://identifiers.org/ec-code/4.2.1.3
fast: false
reversible: true
name: aconitase
type: Reaction

549611
stoichiometry: 1.0
species: metaid OG cyt
type: SpeciesReference

metaid v32
kinetic law: metaid kineticLaw v32
is: http://identifiers.org/ec-code/2.6.1.1
reactant: 549611
fast: false
type: Reaction
reversible: true
product: 549635
product: 549623
name: aspartate transaminase
reactant: 549599

245228
value: 3.3211E-4
name: AGC
type: LocalParameter

245466
value: 3.9E-5
type: LocalParameter

548357
stoichiometry: 1.0
species: metaid FBP
type: SpeciesReference

244954
value: 0.0015
type: LocalParameter

549803
stoichiometry: 1.0
species: metaid CO2
type: SpeciesReference

245546
value: 3.99E-8
type: LocalParameter

245339
value: 1.7E-4
type: LocalParameter

548405
stoichiometry: 1.0
species: metaid DPG
type: SpeciesReference

244964
value: 0.001
type: LocalParameter

548708
stoichiometry: 1.0
species: metaid NADH
type: SpeciesReference

245519
value: 1.5E-4
type: LocalParameter

metaid GTP
is: C00044
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0045
initial amount: NaN
in compartment: metaid MATRIX
name: guanosine triphosphate
type: Species

245183
value: 0.002
type: LocalParameter

548984
stoichiometry: 1.0
species: metaid CoA
type: SpeciesReference

245432
value: 1.0
type: LocalParameter

245465
value: 3.3211E-5
type: LocalParameter

245630
value: 3.3211E-4
name: AAC
type: LocalParameter

244984
value: 5.9E-7
type: LocalParameter

metaid v18
kinetic law: metaid kineticLaw v18
fast: false
reactant: 549068
reactant: 549080
product: 549105
name: malate dehydrogenase (mitochondrion)
type: Reaction
product: 549092
reversible: true
is: http://identifiers.org/ec-code/1.1.1.37

245570
value: 9.0E-8
type: LocalParameter

244862
kinetic law: metaid kineticLaw v22
product: 549249
product: 549237
reactant: 549225
reactant: 549213
fast: false
reversible: true
name: aspartate/glutamate carrier
type: Reaction

metaid ATP
is: C0002
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0045
initial amount: NaN
in compartment: metaid MATRIX
name: adenine triphosphate
type: Species

metaid NADP p
is: C00006
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0101
initial amount: NaN
in compartment: metaid MATRIX
name: NADP+
type: Species

245114
value: 3.8617E-7
name: FM
type: LocalParameter

244974
value: 10000.0
type: LocalParameter

245319
value: 5.0E-4
type: LocalParameter

metaid v28
name: ATPase complex
is: http://identifiers.org/ec-code/3.6.1.5
type: Reaction
reactant: 549429
reversible: true
product: 549466
reactant: 549441
fast: false
product: 549454
kinetic law: metaid kineticLaw v28
is: http://identifiers.org/ec-code/3.6.1.3

245397
value: 0.0083
type: LocalParameter

244953
value: 6.3E-5
type: LocalParameter

245198
value: 3.8617E-7
name: AspTA
type: LocalParameter

245444
value: 3.2E-7
type: LocalParameter

245103
value: 2.5E-5
type: LocalParameter

549237
stoichiometry: 1.0
species: metaid Asp cyt
type: SpeciesReference

metaid v17
kinetic law: metaid kineticLaw v17
product: 549056
reactant: 549044
is: http://identifiers.org/ec-code/4.2.1.2
fast: false
reversible: true
name: fumarase
type: Reaction

244983
value: 5.0E-5
type: LocalParameter

245631
value: 0.333
type: LocalParameter

245495
value: 0.3
type: LocalParameter

metaid PYR cyt
is: C00022
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.22702E-6
initial amount: NaN
in compartment: metaid CYTOPLASM
name: pyruvate
type: Species

metaid GLC
is: C00267
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.12817E-5
initial amount: NaN
in compartment: metaid CYTOPLASM
name: glucose
type: Species

245123
value: 1.7E-4
type: LocalParameter

245531
value: 1.9E-4
type: LocalParameter

245645
value: 3.8617E-7
name: MDH
type: LocalParameter

metaid v27
type: Reaction
reactant: 549393
is: http://identifiers.org/ec-code/2.3.3.1
is: http://identifiers.org/ec-code/2.3.3.3
kinetic law: metaid kineticLaw v27
fast: false
reversible: true
product: 549405
product: 549417
name: citrate synthase
reactant: 549381

244973
value: 10000.0
type: LocalParameter

548586
stoichiometry: 1.0
species: metaid ATP cyt
type: SpeciesReference

245474
value: 2.42E-5
type: LocalParameter

244952
value: 1.0E-4
type: LocalParameter

548417
stoichiometry: 1.0
species: metaid NADH cyt
type: SpeciesReference

245544
value: 3.4E-5
type: LocalParameter

549502
stoichiometry: 1.0
species: metaid Mal cyt
type: SpeciesReference

550079
stoichiometry: 1.0
species: metaid IsoCit
type: SpeciesReference

245420
value: 5.6
type: LocalParameter

548972
stoichiometry: 1.0
species: metaid GTP
type: SpeciesReference

548369
stoichiometry: 2.0
species: metaid GAP
type: SpeciesReference

244966
value: 1000.0
type: LocalParameter

245126
value: 1.1E-5
type: LocalParameter

245195
value: 1000.0
type: LocalParameter

245534
value: 2.4E-4
type: LocalParameter

metaid v16
product: 549032
product: 549020
reactant: 549008
kinetic law: metaid kineticLaw v16
is: http://identifiers.org/ec-code/1.3.5.1
reactant: 548996
reversible: true
name: succinate dehydrogenase
fast: false
type: Reaction

549815
stoichiometry: 1.0
species: metaid Pyr
type: SpeciesReference

244986
value: 6.9E-7
type: LocalParameter

549587
stoichiometry: 1.0
species: metaid NAD
type: SpeciesReference

245477
value: 7.6E-5
type: LocalParameter

244972
value: 0.143
type: LocalParameter

metaid v41
reactant: 549983
modifier: 550031
product: 550007
reversible: true
product: 550019
fast: false
kinetic law: metaid kineticLaw v41
name: cytosolic isocitrate dehydrogenase
is: http://identifiers.org/ec-code/1.1.1.42
reactant: 549995
type: Reaction

245582
value: 6.0E-12
type: LocalParameter

245186
value: 0.0083
type: LocalParameter

245399
value: 6.2
type: LocalParameter

metaid QH2
in compartment: metaid MT IMS
initial amount: NaN
name: ubiquinol
boundary condition: false
has only substance units: false
type: Species
is: CHEBI:17976
initial concentration: 0.028
constant: false
is: C00390

549225
stoichiometry: 1.0
species: metaid Asp
type: SpeciesReference

metaid NADP cyt
initial concentration: 0.00362057
is: CHEBI:18009
initial amount: NaN
constant: false
has only substance units: false
type: Species
boundary condition: false
is: C00006
in compartment: metaid CYTOPLASM
name: NADP

244971
value: 1000.0
type: LocalParameter

metaid AMP
is: C00020
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.61149E-6
initial amount: NaN
in compartment: metaid CYTOPLASM
name: adenine monophosphate
type: Species

244965
value: 0.001
type: LocalParameter

548381
stoichiometry: 1.0
species: metaid GAP
type: SpeciesReference

metaid v15
type: Reaction
product: 548984
product: 548972
reactant: 548936
product: 548960
is: http://identifiers.org/ec-code/6.2.1.4
fast: false
reversible: true
name: succinyl-CoA synthetase
kinetic law: metaid kineticLaw v15
reactant: 548924
reactant: 548948

549309
stoichiometry: 1.0
species: metaid QH2
type: SpeciesReference

245462
value: 101.0
type: LocalParameter

245504
value: 3.7E-4
type: LocalParameter

245105
value: 5.0E-6
type: LocalParameter

549574
stoichiometry: 1.0
species: metaid Mal cyt
type: SpeciesReference

245318
value: 0.0033211
name: Complex_V
type: LocalParameter

metaid v29
kinetic law: metaid kineticLaw v29
product: 549490
reactant: 549478
is: http://identifiers.org/ec-code/4.2.1.3
fast: false
reversible: true
name: aconitase
type: Reaction

245483
value: 7.53E-5
type: LocalParameter

245647
constant: true
value: 0.011
type: Parameter

548574
stoichiometry: 1.0
species: metaid AMP
type: SpeciesReference

245456
value: 0.66
type: LocalParameter

metaid Pyr
is: C00022
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.001025
initial amount: NaN
in compartment: metaid MATRIX
name: pyruvate
type: Species

metaid CoA
is: C00010
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.72E-4
initial amount: NaN
in compartment: metaid MATRIX
name: coenzyme A
type: Species

548672
stoichiometry: 1.0
species: metaid NAD p
type: SpeciesReference

245543
value: 3.8617E-7
name: PC
type: LocalParameter

245111
value: 900.0
type: LocalParameter

549947
stoichiometry: 1.0
species: metaid NAD
type: SpeciesReference

245036
value: 2.5E-5
type: LocalParameter

245423
value: 3.5
type: LocalParameter

549080
stoichiometry: 1.0
species: metaid NAD p
type: SpeciesReference

245022
value: 2.5E-5
type: LocalParameter

metaid MT IMS
is: GO:0005758
constant: true
size: 1.0
spatial dimensions: 3.0
name: mitochondrial intermembrane space
type: Compartment

metaid GAP
is: C00118
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.90919E-6
initial amount: NaN
in compartment: metaid CYTOPLASM
name: glyceraldehyde 3-phosphate
type: Species

549731
stoichiometry: 1.0
species: metaid QH2
type: SpeciesReference

548441
stoichiometry: 1.0
species: metaid ADP cyt
type: SpeciesReference

245135
value: 0.0019
type: LocalParameter

548780
stoichiometry: 1.0
species: metaid IsoCit
type: SpeciesReference

549899
stoichiometry: 1.0
species: metaid DHAP
type: SpeciesReference

548489
stoichiometry: 1.0
species: metaid ADP cyt
type: SpeciesReference

245222
value: 1.0
type: LocalParameter

245093
value: 0.037
type: LocalParameter

244955
value: 1.6E-9
type: LocalParameter

245375
value: 1400.0
type: LocalParameter

245417
value: 4.18E-5
type: LocalParameter

245385
value: 9.0E-4
type: LocalParameter

245561
value: 3.3211E-4
name: AAC
type: LocalParameter

549201
stoichiometry: 1.0
species: metaid OG
type: SpeciesReference

metaid FADH2
is: C01352
constant: false
boundary condition: false
has only substance units: false
initial concentration: 7.2E-5
initial amount: NaN
in compartment: metaid MATRIX
name: FADH2
type: Species

245336
value: 0.0014
type: LocalParameter

549417
stoichiometry: 1.0
species: metaid Acetyl CoA cyt
type: SpeciesReference

245037
value: 177.0
type: LocalParameter

548888
stoichiometry: 1.0
species: metaid CO2
type: SpeciesReference

245459
value: 78.0
type: LocalParameter

metaid GDP
is: C00035
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.5E-4
initial amount: NaN
in compartment: metaid MATRIX
name: guanosine diphosphate
type: Species

549285
stoichiometry: 1.0
species: metaid NAD p
type: SpeciesReference

245108
value: 800.0
type: LocalParameter

245345
value: 4.83
type: LocalParameter

BIOMD0000000239
compartment: metaid MATRIX
reaction: metaid v29
reaction: 244769
reaction: metaid v37
species: metaid Cit cyt
reaction: metaid v17
compartment: metaid CYTOPLASM
species: metaid Mal cyt
species: metaid OXA cyt
reaction: metaid v10
reaction: metaid v1
reaction: 244770
parameter: 245647
species: metaid Glu cyt
species: metaid IsoCit
reaction: 244927
compartment: metaid MT IM
reaction: metaid v4
reaction: metaid v7
species: metaid Glu
species: metaid NAD
species: metaid FBP
species: metaid FAD
reaction: metaid v25
species: metaid G3P
species: metaid NADP cyt
reaction: metaid v28
species: metaid Pyr
reaction: metaid v36
reaction: metaid v16
species: metaid CO2
species: metaid IsoCitcyt
species: metaid DHAP
species: metaid OXA
reaction: 244935
species: metaid Q
species: metaid Ala
compartment: metaid MT IMS
species: metaid NAD p
species: metaid ADP cyt
species: metaid ETFox
substance units: metaid_0000028
species: metaid OG cyt
species: metaid ADP
species: metaid NADPH
species: metaid CoA cyt
is version of: GO:0061178
reaction: 244903
species: metaid Acetyl CoA
species: metaid ATP
species: metaid Suc
reaction: metaid v41
species: metaid H2O
reaction: metaid v21
volume units: metaid_0000004
reaction: metaid v39
species: metaid Cit
species: metaid Acetyl CoA cyt
occurs in: http://identifiers.org/taxonomy/9606
reaction: metaid v6
reaction: metaid v44
species: metaid GAP
reaction: metaid v24
species: metaid OG
species: metaid ETFred
species: metaid LAC
species: metaid CoA
reaction: metaid v32
reaction: metaid v12
length unit: length
reaction: metaid v3
species: metaid Asp
species: metaid NADPH cyt
species: metaid SCoA
reaction: 244804
reaction: metaid v9
curated: true
reaction: metaid v27
time units: metaid_0000029
reaction: 244767

245189
value: 6.2
type: LocalParameter

549153
stoichiometry: 1.0
species: metaid Pyr
type: SpeciesReference

244956
value: 0.017
type: LocalParameter

metaid SCoA
is: C00091
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.941E-4
initial amount: NaN
in compartment: metaid MATRIX
name: succinyl-CoA
type: Species

metaid CO2
is: C00011
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00163
initial amount: NaN
in compartment: metaid MATRIX
name: carbon dioxide
type: Species

245402
value: 300.0
type: LocalParameter

metaid ETFred
is: C04570
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.1E-4
initial amount: NaN
in compartment: metaid MATRIX
name: electron transfer flavoprotein (reduced form)
type: Species

245562
value: 0.051
type: LocalParameter

549008
stoichiometry: 1.0
species: metaid Q
type: SpeciesReference

244946
value: 64.941
type: LocalParameter

549743
stoichiometry: 1.0
species: metaid FADH2
type: SpeciesReference

548453
stoichiometry: 1.0
species: metaid PEP
type: SpeciesReference

245034
value: 8.1E-5
type: LocalParameter

245147
value: 4.0E-4
type: LocalParameter

245435
value: 1.0
type: LocalParameter

245024
value: 5.0E-5
type: LocalParameter

245348
value: 1.0
type: LocalParameter

549935
stoichiometry: 1.0
species: metaid G3P
type: SpeciesReference

549105
stoichiometry: 1.0
species: metaid OXA
type: SpeciesReference

245405
value: 1000.0
type: LocalParameter

245387
value: 1.0E-4
type: LocalParameter

245234
value: 9.9E-6
type: LocalParameter

549213
stoichiometry: 1.0
species: metaid Glu cyt
type: SpeciesReference

549887
stoichiometry: 1.0
species: metaid FADH2
type: SpeciesReference

245540
value: 20.0
type: LocalParameter

548720
stoichiometry: 1.0
species: metaid OXA
type: SpeciesReference

metaid OG cyt
is: C00026
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.1E-5
initial amount: NaN
in compartment: metaid CYTOPLASM
name: oxoglutarate
type: Species

549273
stoichiometry: 1.0
species: metaid Q
type: SpeciesReference

244903
reactant: 549647
fast: false
is version of: GO:0015137
name: citrate carrier
product: 549683
type: Reaction
product: 549671
kinetic law: metaid kineticLaw v33
reversible: true
reactant: 549659

245360
value: 3.3211E-4
name: OGC
type: LocalParameter

245333
value: 7.0E-4
type: LocalParameter

549405
stoichiometry: 1.0
species: metaid OXA cyt
type: SpeciesReference

245025
value: 3.0E-4
type: LocalParameter

245447
value: 4.2E-9
type: LocalParameter

245249
value: 498.0
type: LocalParameter

245414
value: 3.3E-4
type: LocalParameter

245550
value: 34.0
type: LocalParameter

245090
value: 5.6E-6
type: LocalParameter

245309
value: 3.8617E-7
name: CS
type: LocalParameter

245138
value: 0.39
type: LocalParameter

244958
value: 1.0E-5
type: LocalParameter

metaid Fum
is: C00122
constant: false
boundary condition: false
has only substance units: false
initial concentration: 6.5E-5
initial amount: NaN
in compartment: metaid MATRIX
name: fumarate
type: Species

metaid NADPH
is: C00005
constant: false
boundary condition: false
has only substance units: false
initial concentration: 7.2E-5
initial amount: NaN
in compartment: metaid MATRIX
name: NADPH
type: Species

245177
value: 4.0E-5
type: LocalParameter

549165
stoichiometry: 1.0
species: metaid OXA
type: SpeciesReference

548538
stoichiometry: 1.0
species: metaid NADH cyt
type: SpeciesReference

549117
stoichiometry: 1.0
species: metaid Ala
type: SpeciesReference

245159
value: 0.012
type: LocalParameter

245246
value: 407.9
type: LocalParameter

244969
value: 2.0E-4
type: LocalParameter

548465
stoichiometry: 1.0
species: metaid ATP cyt
type: SpeciesReference

245351
value: 1.0
type: LocalParameter

245342
value: 3.675
type: LocalParameter

245361
value: 3.4E7
type: LocalParameter

245256
value: 2.8E-5
type: LocalParameter

244995
value: 856.0
type: LocalParameter

245312
value: 0.0045
type: LocalParameter

245012
value: 105.0
type: LocalParameter

244959
value: 1.0
type: LocalParameter

244949
value: 5.0E-4
type: LocalParameter

245381
value: 260000.0
type: LocalParameter

548526
stoichiometry: 1.0
species: metaid PYR cyt
type: SpeciesReference

metaid Ala
is: C00041
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00344
initial amount: NaN
in compartment: metaid MATRIX
name: slanine
type: Species

245331
value: 3.0E-4
type: LocalParameter

245237
value: 5.9E-5
type: LocalParameter

245426
value: 1.0
type: LocalParameter

244996
value: 3.8617E-7
name: PDC
type: LocalParameter

245199
value: 8.0E-5
type: LocalParameter

245033
value: 1.1E-6
type: LocalParameter

548864
stoichiometry: 1.0
species: metaid CoA
type: SpeciesReference

549393
stoichiometry: 1.0
species: metaid CoA cyt
type: SpeciesReference

W3 CDTF: Tue Nov 29 12:14:22 GMT 2011

metaid IsoCit
is: C00311
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.2E-4
initial amount: NaN
in compartment: metaid MATRIX
name: isocitrate
type: Species

245552
value: 0.0399
type: LocalParameter

245321
value: 1.1E-4
type: LocalParameter

245372
value: 26.0
type: LocalParameter

metaid Cit
is: C00158
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.2E-4
initial amount: NaN
in compartment: metaid MATRIX
name: citrate
type: Species

metaid NAD p
is: C00003
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0101
initial amount: NaN
in compartment: metaid MATRIX
name: NAD+
type: Species

metaid DHAP
is: C00111
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0076925
initial amount: NaN
in compartment: metaid CYTOPLASM
name: dihydrohxyacetone-phosphate
type: Species

245411
value: 4.4E-4
type: LocalParameter

245324
value: 20.47
type: LocalParameter

245020
value: 3.8617E-7
name: IDHa
type: LocalParameter

245439
value: 3.1E-7
type: LocalParameter

245330
value: 3.8617E-7
name: ACO
type: LocalParameter

245429
value: 1.0
type: LocalParameter

244967
value: 500.0
type: LocalParameter

548792
stoichiometry: 1.0
species: metaid IsoCit
type: SpeciesReference

244997
value: 0.005267
type: LocalParameter

548477
stoichiometry: 1.0
species: metaid PEP
type: SpeciesReference

245030
value: 7.4E-4
type: LocalParameter

245363
value: 3.5E7
type: LocalParameter

549129
stoichiometry: 1.0
species: metaid OG
type: SpeciesReference

245010
value: 3.8617E-7
name: ACO
type: LocalParameter

245258
value: 3.0E-6
type: LocalParameter

245310
value: 0.075
type: LocalParameter

549959
stoichiometry: 1.0
species: metaid ADP cyt
type: SpeciesReference

245000
value: 4.8E-6
type: LocalParameter

549791
stoichiometry: 1.0
species: metaid ATP
type: SpeciesReference

245225
value: 1.0
type: LocalParameter

245438
value: 3.3211E-4
name: CIC
type: LocalParameter

245021
value: 2.2E-4
type: LocalParameter

245031
value: 1.0E-4
type: LocalParameter

244968
value: 0.01
type: LocalParameter

549141
stoichiometry: 1.0
species: metaid Glu
type: SpeciesReference

244998
value: 1.18E-5
type: LocalParameter

548514
stoichiometry: 1.0
species: metaid ATP cyt
type: SpeciesReference

245564
value: 9.5E-8
type: LocalParameter

549297
stoichiometry: 1.0
species: metaid QH2
type: SpeciesReference

244927
kinetic law: metaid kineticLaw v40
product: 549971
reactant: 549959
is version of: GO:0015217
fast: false
reversible: false
name: ATP/ADP carrier
type: Reaction

245384
value: 3.8617E-7
name: MDH
type: LocalParameter

549429
stoichiometry: 1.0
species: metaid ADP
type: SpeciesReference

245001
value: 1.0E-5
type: LocalParameter

549381
stoichiometry: 1.0
species: metaid Cit cyt
type: SpeciesReference

548876
stoichiometry: 1.0
species: metaid NAD p
type: SpeciesReference

metaid G3P
is: C00093
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0076925
initial amount: NaN
in compartment: metaid CYTOPLASM
name: glycerol-3-phosphate
type: Species

245603
value: 4.18E-5
type: LocalParameter

metaid PEP
is: C00074
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.1125E-6
initial amount: NaN
in compartment: metaid CYTOPLASM
name: phosphoenolpyruvate
type: Species

245002
value: 4.0E-6
type: LocalParameter

245213
value: 10.0
type: LocalParameter

244991
value: 6.0E-5
type: LocalParameter

548804
stoichiometry: 1.0
species: metaid NAD p
type: SpeciesReference

548756
stoichiometry: 1.0
species: metaid CoA
type: SpeciesReference

245252
value: 229.0
type: LocalParameter

245043
value: 4.5E-4
type: LocalParameter

metaid F6P
is: C00085
constant: false
boundary condition: false
has only substance units: false
initial concentration: 6.5939E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: fructose-6-phosphate
type: Species

metaid v6
reactant: 548489
reactant: 548477
type: Reaction
product: 548501
reversible: false
name: pyruvate kinase
fast: false
kinetic law: metaid kineticLaw v6
product: 548514
is: http://identifiers.org/ec-code/2.7.1.40

245016
value: 7.8E-5
type: LocalParameter

549695
stoichiometry: 1.0
species: metaid ETFred
type: SpeciesReference

245141
value: 0.04
type: LocalParameter

245057
value: 2.0E-5
type: LocalParameter

metaid Suc
is: C00042
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00295
initial amount: NaN
in compartment: metaid MATRIX
name: succinate
type: Species

245156
value: 0.0087
type: LocalParameter

metaid NADH
is: C00004
constant: false
boundary condition: false
has only substance units: false
initial concentration: 7.2E-4
initial amount: NaN
in compartment: metaid MATRIX
name: NADH
type: Species

245303
value: 0.0043
type: LocalParameter

244935
kinetic law: metaid kineticLaw v43
product: 550103
reactant: 550091
is version of: GO:0005347
fast: false
reversible: false
name: ATP/ADP carrier
type: Reaction

244992
value: 3.5E-5
type: LocalParameter

245612
value: 1.0
type: LocalParameter

548321
stoichiometry: 1.0
species: metaid FBP
type: SpeciesReference

549779
stoichiometry: 1.0
species: metaid FAD
type: SpeciesReference

metaid Pi
is: C00009
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.004
initial amount: NaN
in compartment: metaid MATRIX
name: phosphate
type: Species

245042
value: 3.5E-5
type: LocalParameter

549333
stoichiometry: 1.0
species: metaid Q
type: SpeciesReference

245366
value: 4650.0
type: LocalParameter

metaid v5
is: http://identifiers.org/ec-code/5.4.2.4
reactant: 548441
type: Reaction
product: 548465
name: bisphosphoglycerate phosphotase (1/2)
reversible: true
product: 548453
is: http://identifiers.org/ec-code/5.4.2.1
fast: false
reactant: 548429
kinetic law: metaid kineticLaw v5

550151
stoichiometry: 1.0
species: metaid PYR cyt
type: SpeciesReference

549851
stoichiometry: 1.0
species: metaid OXA
type: SpeciesReference

metaid Glu cyt
is: C00025
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.00303
initial amount: NaN
in compartment: metaid CYTOPLASM
name: glutamate
type: Species

550091
stoichiometry: 1.0
species: metaid ATP
type: SpeciesReference

245243
value: 9.8E-8
type: LocalParameter

549020
stoichiometry: 1.0
species: metaid Fum
type: SpeciesReference

245004
value: 3.8617E-7
name: CS
type: LocalParameter

548768
stoichiometry: 1.0
species: metaid Cit
type: SpeciesReference

245579
value: 2.5E-4
type: LocalParameter

metaid ETFox
is: C04253
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.2E-4
initial amount: NaN
in compartment: metaid MATRIX
name: electron transfer flavoprotein (oxidised form)
type: Species

metaid CYTOPLASM
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: cytoplasm
type: Compartment

metaid IsoCitcyt
is: C00311
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.2E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: isocitrate
type: Species

245099
value: 1.73
type: LocalParameter

245294
value: 3.9E-5
type: LocalParameter

245615
value: 1.0
type: LocalParameter

548852
stoichiometry: 1.0
species: metaid OG
type: SpeciesReference

245201
value: 0.0032
type: LocalParameter

245014
value: 29.6
type: LocalParameter

245045
value: 6.0E-4
type: LocalParameter

245240
value: 2.1E-8
type: LocalParameter

549683
stoichiometry: 1.0
species: metaid Cit
type: SpeciesReference

549538
stoichiometry: 1.0
species: metaid Mal
type: SpeciesReference

245600
value: 3.3E-4
type: LocalParameter

metaid CoA cyt
is: C00010
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.72E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: coenzyme A
type: Species

metaid Cit cyt
is: C00158
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.2E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: citrate
type: Species

245015
value: 2.3E-4
type: LocalParameter

245168
value: 0.15
type: LocalParameter

245255
value: 3.3211E-4
name: Complex_I
type: LocalParameter

metaid OXA
is: C00036
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.0E-6
initial amount: NaN
in compartment: metaid MATRIX
name: oxaloacetate
type: Species

549032
stoichiometry: 1.0
species: metaid QH2
type: SpeciesReference

metaid v7
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.27
product: 548550
product: 548562
name: lactate dehydrogenase
reactant: 548538
kinetic law: metaid kineticLaw v7
reactant: 548526
reversible: true
fast: false

244994
value: 3.6E-5
type: LocalParameter

549345
stoichiometry: 2.0
species: metaid Cytc2p
type: SpeciesReference

245054
value: 4.0E-4
type: LocalParameter

metaid MT IM
is: GO:0005743
constant: true
size: 1.0
spatial dimensions: 3.0
name: mitochondrial inner membrane
type: Compartment

245005
value: 5.0E-4
type: LocalParameter

245354
value: 1.0
type: LocalParameter

245369
value: 214.0
type: LocalParameter

549671
stoichiometry: 1.0
species: metaid Mal cyt
type: SpeciesReference

245165
value: 337.0
type: LocalParameter

548598
stoichiometry: 2.0
species: metaid ADP cyt
type: SpeciesReference

245006
value: 1.1E-4
type: LocalParameter

metaid FBP
is: C00354
constant: false
boundary condition: false
has only substance units: false
initial concentration: 7.70135E-6
initial amount: NaN
in compartment: metaid CYTOPLASM
name: fructose-1,6-bisphosphate
type: Species

549261
stoichiometry: 1.0
species: metaid NADH
type: SpeciesReference

548732
stoichiometry: 1.0
species: metaid Acetyl CoA
type: SpeciesReference

245145
value: 0.002
type: LocalParameter

245282
value: 9.35E-4
type: LocalParameter

245066
value: 5.0E-6
type: LocalParameter

metaid v9
reversible: false
name: pyruvate dehydrogenase complex
reactant: 548672
fast: false
product: 548684
product: 548708
reactant: 548659
reactant: 548647
product: 548696
is: http://identifiers.org/ec-code/1.2.4.1
kinetic law: metaid kineticLaw v9
type: Reaction

548297
stoichiometry: 1.0
species: metaid F6P
type: SpeciesReference

245096
value: 69.3
type: LocalParameter

549875
stoichiometry: 1.0
species: metaid FAD
type: SpeciesReference

245606
value: 5.6
type: LocalParameter

245027
value: 6.0E-4
type: LocalParameter

549923
stoichiometry: 1.0
species: metaid DHAP
type: SpeciesReference

548659
stoichiometry: 1.0
species: metaid CoA
type: SpeciesReference

245007
value: 20.47
type: LocalParameter

245132
value: 0.0071
type: LocalParameter

549755
stoichiometry: 1.0
species: metaid ETFox
type: SpeciesReference

245046
value: 7.5E-6
type: LocalParameter

245069
value: 6.7E-6
type: LocalParameter

245049
value: 6.0E-4
type: LocalParameter

245357
value: 1.0
type: LocalParameter

245028
value: 7.2E-4
type: LocalParameter

245153
value: 4.0E-4
type: LocalParameter

245409
value: 1.3E-4
type: LocalParameter

245306
value: 1.8E7
type: LocalParameter

245270
value: 1.9E-6
type: LocalParameter

548744
stoichiometry: 1.0
species: metaid Cit
type: SpeciesReference

245008
value: 31.44
type: LocalParameter

245018
value: 6.4E-4
type: LocalParameter

245280
value: 1.1E-4
type: LocalParameter

245408
value: 3.8617E-7
name: AspTA
type: LocalParameter

548948
stoichiometry: 1.0
species: metaid Pi
type: SpeciesReference

245039
value: 3.8617E-7
name: OGDC
type: LocalParameter

metaid Acetyl CoA cyt
is: C00024
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.0E-5
initial amount: NaN
in compartment: metaid CYTOPLASM
name: acetyl CoA
type: Species

549911
stoichiometry: 1.0
species: metaid NADH cyt
type: SpeciesReference

245231
value: 2.6E-4
type: LocalParameter

548647
stoichiometry: 1.0
species: metaid Pyr
type: SpeciesReference

244990
value: 1.8E-4
type: LocalParameter

244933
name: citrate carrier
kinetic law: metaid kineticLaw v42
product: 550067
type: Reaction
fast: false
reactant: 550043
product: 550079
reversible: true
is version of: GO:0006843
reactant: 550055

metaid Mal cyt
is: C00149
constant: false
boundary condition: false
has only substance units: false
initial concentration: 5.0E-4
initial amount: NaN
in compartment: metaid CYTOPLASM
name: malate
type: Species

245210
value: 10.0
type: LocalParameter

549321
stoichiometry: 2.0
species: metaid Cytc3p
type: SpeciesReference

549863
stoichiometry: 1.0
species: metaid G3P
type: SpeciesReference

245291
value: 4.5E-6
type: LocalParameter

548285
stoichiometry: 1.0
species: metaid ADP cyt
type: SpeciesReference

245618
value: 1.0
type: LocalParameter

245378
value: 570000.0
type: LocalParameter

245078
value: 6.9E-5
type: LocalParameter

metaid Cytc3p
constant: false
name: ferrocytochrome c
is: C00126
has only substance units: false
boundary condition: false
initial amount: NaN
in compartment: metaid MT IMS
type: Species
initial concentration: 0.003
is: CHEBI:16928

549767
stoichiometry: 1.0
species: metaid ETFred
type: SpeciesReference

245048
value: 4.5E-4
type: LocalParameter

245019
value: 3.6E-4
type: LocalParameter

metaid Cytc2p
boundary condition: false
initial amount: NaN
has only substance units: false
constant: false
in compartment: metaid MT IMS
is: CHEBI:15991
type: Species
is: C00125
initial concentration: 1.1E-4
name: ferricytochrome c

549092
stoichiometry: 1.0
species: metaid NADH
type: SpeciesReference

245144
value: 3.8617E-7
name: MDH
type: LocalParameter

orgname: EMBL-EBI

given: Vijayalakshmi
family: Chelliah

ORG:
  orgname: University of Manchester
n:
  given: Kieran
  family: Smallbone

W3 CDTF: Wed Jun 05 22:07:22 BST 2013