metaid_0100172
kinetic law: 390536
modifier: 390524
product: 390512
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false
type: Reaction

389801
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

389753
exponent: 1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

390476
stoichiometry: 1.0
species: metaid_0000107
type: SpeciesReference

390949
stoichiometry: 1.0
species: metaid_0000112
type: SpeciesReference

metaid_0000180
modifier: 390816
product: 390804
kinetic law: 390852
reversible: false
is version of: GO:0051091
fast: false
type: Reaction
modifier: 390828
modifier: 390840

metaid_0000168
is version of: REACT 11065.1
is: SBO:0000216
modifier: 390308
fast: false
reversible: false
product: 390284
reactant: 390272
kinetic law: 390332
modifier: 390296
is version of: GO:0006468
modifier: 390320
type: Reaction

metaid_0110172
kinetic law: 390500
modifier: 390488
product: 390476
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false
type: Reaction

metaid_0000097
type: Species
in compartment: metaid_0000095
is version of: IPR008297
has only substance units: false
name: Notch protein
constant: false
boundary condition: false
is: SBO:0000252
initial concentration: 0.5
is homolog to: P46531
initial amount: NaN

metaid_0000158
kinetic law: 389983
reactant: 389971
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
name: Na_degradation
type: Reaction

metaid_0000119
initial concentration: 2.0
is: SBO:0000252
is homolog to: O14640
in compartment: metaid_0000095
constant: false
name: Dsh protein
boundary condition: false
type: Species
is version of: IPR003351
initial amount: NaN
has only substance units: false

390284
stoichiometry: 1.0
species: metaid_0000102
type: SpeciesReference

389898
stoichiometry: 1.0
species: metaid_0000097
type: SpeciesReference

metaid_0000182
kinetic law: 390913
modifier: 390901
product: 390889
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false
type: Reaction

metaid_0000013
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.001
name: KdNa
type: Parameter

390188
stoichiometry: 1.0
species: metaid_0000104
type: SpeciesReference

metaid_0000181
kinetic law: 390877
reactant: 390865
is version of: GO:0043433
fast: false
reversible: false
type: Reaction

metaid_0000167
kinetic law: 390260
reactant: 390248
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
type: Reaction

metaid_0000139
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.0
name: VMP
type: Parameter

metaid_0000157
is: SBO:0000178
is version of: GO:0007220
kinetic law: 389959
product: 389934
reactant: 389922
type: Reaction
modifier: 389946
name: Notch_activation
fast: false
reversible: false
is version of: REACT 691.2

390224
stoichiometry: 1.0
species: metaid_0000106
type: SpeciesReference

389741
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000057
is: SBO:0000186
constant: true
units: metaid_0000006
value: 2.0
name: vdDusp
type: Parameter

390007
stoichiometry: 1.0
species: metaid_0000099
type: SpeciesReference

metaid_0000095
is: GO:0005829
constant: true
units: litre
size: 1.0
spatial dimensions: 3.0
type: Compartment

metaid_0000156
kinetic law: 389910
reactant: 389898
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
name: N_degradation
type: Reaction

metaid_0000010
is: SBO:0000048
constant: true
units: metaid_0000006
value: 0.23
name: vsN
type: Parameter

metaid_0000080
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KaErk
type: Parameter

390272
stoichiometry: 1.0
species: metaid_0000106
type: SpeciesReference

390633
stoichiometry: 1.0
species: metaid_0000108
type: SpeciesReference

metaid_0000042
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.63
name: KdAx
type: Parameter

390031
stoichiometry: 1.0
species: metaid_0000099
type: SpeciesReference

metaid_0000093
is: SBO:0000381
constant: true
units: dimensionless
value: 1.5
name: theta
type: Parameter

metaid_0000056
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.5
name: ksDusp
type: Parameter

metaid_0000155
kinetic law: 389886
product: 389874
is version of: GO:0010467
fast: false
reversible: false
name: Notch_synthesis
type: Reaction

metaid_0000169
kinetic law: 390368
product: 390356
reactant: 390344
is version of: GO:0006470
is: SBO:0000330
fast: false
reversible: false
type: Reaction

metaid_0000094
is: SBO:0000381
constant: true
units: dimensionless
value: 0.3
name: eta
type: Parameter

390548
stoichiometry: 1.0
species: metaid_0000107
type: SpeciesReference

metaid_0000011
is: SBO:0000324
constant: true
units: metaid_0000006
value: 2.82
name: vdN
type: Parameter

metaid_0000092
is: SBO:0000381
constant: true
units: dimensionless
value: 0.3
name: epsilon
type: Parameter

metaid_0000051
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.03
name: K2
type: Parameter

389995
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

metaid_0000083
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.5
name: KID
type: Parameter

metaid_0000041
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.6
name: vdAx
type: Parameter

390707
stoichiometry: 1.0
species: metaid_0000109
type: SpeciesReference

metaid_0000102
is homolog to: P35222
has only substance units: false
is: SBO:0000252
constant: false
is version of: C00562
in compartment: metaid_0000095
initial amount: NaN
name: phosph. beta-catenin
boundary condition: false
type: Species
is version of: IPR013284
initial concentration: 0.1

metaid_0000116
initial amount: NaN
initial concentration: 2.0
in compartment: metaid_0000095
is version of: IPR001806
boundary condition: false
constant: false
name: Ras total
type: Species
is: SBO:0000252
has only substance units: false

metaid_0000141
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.41
name: VMdRas
type: Parameter

metaid_0000082
is: SBO:0000191
constant: true
units: metaid_0000007
value: 0.5
name: KIF
type: Parameter

metaid_0000016
is: SBO:0000032
constant: true
units: metaid_0000004
value: 0.1
name: kt2
type: Parameter

metaid_0000021
is: SBO:0000186
constant: false
units: metaid_0000006
value: NaN
name: vsFK
type: Parameter

metaid_0000031
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.06
name: v0
type: Parameter

metaid_0000101
boundary condition: false
type: Species
in compartment: metaid_0000095
has only substance units: false
initial amount: NaN
is: SBO:0000252
is version of: IPR017374
constant: false
is homolog to: Q8NES3
name: Lunatic Fringe protein
initial concentration: 0.001

metaid_0000091
is: SBO:0000191
constant: true
units: dimensionless
value: 2.0
name: p
type: Parameter

metaid_0000050
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.28
name: K1
type: Parameter

metaid_0000040
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.02
name: ksAx
type: Parameter

390248
stoichiometry: 1.0
species: metaid_0000106
type: SpeciesReference

metaid_0000115
is version of: IPR006715
has only substance units: false
is: SBO:0000252
boundary condition: true
initial amount: NaN
in compartment: metaid_0000095
constant: false
initial concentration: NaN
type: Species
name: inactive TF X

metaid_0000142
is: SBO:0000186
constant: true
units: metaid_0000006
value: 3.3
name: VMaErk
type: Parameter

metaid_0000020
constant: true
units: metaid_0000007
value: 2.5
name: KIG1
type: Parameter

BIOMD0000000201
species: metaid_0000100
parameter: metaid_0000011
reaction: metaid_0110172
reaction: metaid_0000169
species: metaid_0000047
reaction: metaid_0000160
parameter: metaid_0000090
rule: metaid_0000123
reaction: metaid_0000176
parameter: metaid_0000036
rule: metaid_0000134
species: metaid_0000119
species: metaid_0000101
reaction: metaid_0000172
parameter: metaid_0000048
parameter: metaid_0000039
reaction: metaid_0000168
reaction: metaid_0000167
parameter: metaid_0000028
species: metaid_0000112
units def: metaid_0000007
reaction: metaid_0000157
is: MODEL6415057828
parameter: metaid_0000034
has version: GO:0007219
units def: metaid_0010003
parameter: metaid_0000050
parameter: metaid_0000076
volume units: metaid_0000005
parameter: metaid_0000057
species: metaid_0000117
parameter: metaid_0000030
parameter: metaid_0000094
parameter: metaid_0000085
parameter: metaid_0000137
parameter: metaid_0000053
parameter: metaid_0000088
parameter: metaid_0000079
occurs in: http://identifiers.org/taxonomy/32524
parameter: metaid_0000027
has version: ko04330
parameter: metaid_0000143
parameter: metaid_0000139
reaction: metaid_0000155
parameter: metaid_0000042
parameter: metaid_0000016
parameter: metaid_0000033
species: metaid_0000107
species: metaid_0000110
has version: GO:0016055
notes: This is a model of the coupled Natch, Wnt and FGF modules as described in: A. Goldbeter and O. Pourquié , Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways. J Theor Biol. 2008 Jun 7;252(3):574-85, pubmed ID: 18308339 To uncouple the modules remove the reaction MAx_trans_Xa and set vsFK=vsF . The SBML version of the model was converted from the CellML version by Catherine Lloyd for the CellML repository . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
parameter: metaid_0000018
parameter: metaid_0000022
substance units: metaid_0010003
species: metaid_0000099
parameter: metaid_0000081
parameter: metaid_0000136
species: metaid_0000104
parameter: metaid_0000087
parameter: metaid_0000142
reaction: metaid_0000183
parameter: metaid_0000041
parameter: metaid_0000015
species: metaid_0000111
parameter: metaid_0000067
reaction: metaid_0000180
length unit: length
units def: metaid_0000005
reaction: metaid_0000163
parameter: metaid_0000093
species: metaid_0000075
parameter: metaid_0000021
species: metaid_0000105
has version: REACT 299.2
parameter: metaid_0000010
is part of: GO:0001756
parameter: metaid_0000080
has version: ko04010
reaction: metaid_0000175
reaction: metaid_0000166

metaid_0000017
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.001
name: KdNan
type: Parameter

metaid_0000081
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KaX
type: Parameter

W3 CDTF: Fri Nov 07 15:03:43 GMT 2008

metaid_0000003
unit: 389753
name: minute
type: SBMLUnitsDef

390985
stoichiometry: 1.0
species: metaid_0000112
type: SpeciesReference

metaid_0000030
is: SBO:0000022
constant: true
units: metaid_0000004
value: 7.062
name: kd2
type: Parameter

metaid_0000053
is: SBO:0000032
constant: true
units: metaid_0000004
value: 1.5
name: kt4
type: Parameter

metaid_0000100
type: Species
initial concentration: 0.1
is version of: CHEBI:33699
in compartment: metaid_0000095
name: Lunatic fringe mRNA
has only substance units: false
is: SBO:0000250
encodes: Q8NES3
initial amount: NaN
encodes: IPR017374
constant: false
boundary condition: false

metaid_0000090
is: SBO:0000191
constant: true
units: dimensionless
value: 2.0
name: j
type: Parameter

390609
stoichiometry: 1.0
species: metaid_0000104
type: SpeciesReference

metaid_0000118
is: SBO:0000252
initial concentration: 2.0
in compartment: metaid_0000095
name: X total
is version of: IPR006715
constant: false
has only substance units: false
boundary condition: false
initial amount: NaN
type: Species

390440
stoichiometry: 1.0
species: metaid_0000107
type: SpeciesReference

metaid_0000085
is: SBO:0000191
constant: true
units: metaid_0000007
value: 0.5
name: KaMDusp
type: Parameter

metaid_0000014
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.01
name: VdNa
type: Parameter

metaid_0000004
unit: 389765
name: first_order_rate_constant
type: SBMLUnitsDef

metaid_0000033
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.8
name: vmd
type: Parameter

metaid_0000052
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.7
name: kt3
type: Parameter

metaid_0000117
initial amount: NaN
type: Species
is: SBO:0000252
in compartment: metaid_0000095
is version of: IPR008349
boundary condition: false
name: ERK total
constant: false
initial concentration: 2.0
has only substance units: false

390344
stoichiometry: 1.0
species: metaid_0000102
type: SpeciesReference

metaid_0000179
kinetic law: 390792
modifier: 390780
reactant: 390768
is version of: REACT 12436.1
fast: false
reversible: false
type: Reaction

metaid_0000084
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KdX
type: Parameter

metaid_0000140
is: SBO:0000186
constant: true
units: metaid_0000006
value: 4.968
name: VMaRas
type: Parameter

metaid_0000015
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.1
name: kt1
type: Parameter

metaid_0000159
reactant: 389995
kinetic law: 390019
is version of: REACT 2155.3
reversible: true
product: 390007
type: Reaction
is: SBO:0000185
fast: false
is version of: GO:0006913

390889
stoichiometry: 1.0
species: metaid_0000111
type: SpeciesReference

metaid_0000005
unit: 389801
unit: 389789
unit: 389777
name: second_order_rate_constant
type: SBMLUnitsDef

metaid_0000032
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.64
name: vMB
type: Parameter

metaid_0000025
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.37
name: KdF
type: Parameter

metaid_0000007
unit: 389862
unit: 389850
name: nanomolar
type: SBMLUnitsDef

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

metaid_0000035
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KaXa
type: Parameter

389826
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

390092
stoichiometry: 1.0
species: metaid_0000100
type: SpeciesReference

390682
stoichiometry: 1.0
species: metaid_0000108
type: SpeciesReference

389934
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

metaid_0000160
kinetic law: 390043
reactant: 390031
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
type: Reaction

metaid_0000105
initial concentration: 3.0
in compartment: metaid_0000095
has only substance units: false
constant: false
boundary condition: false
initial amount: NaN
is homolog to: P49841
is: SBO:0000252
type: Species
name: Gsk3

390356
stoichiometry: 1.0
species: metaid_0000106
type: SpeciesReference

metaid_0000178
type: Reaction
fast: false
modifier: 390719
is version of: REACT 1482.4
product: 390707
modifier: 390744
reversible: false
kinetic law: 390756
modifier: 390731

metaid_0010003
unit: 389741
name: nanomole
type: SBMLUnitsDef

metaid_0000111
name: Dusp6 mRNA
is: SBO:0000250
type: Species
initial amount: NaN
has only substance units: false
in compartment: metaid_0000095
encodes: Q16828
boundary condition: false
is homolog to: ENSG00000139318
constant: false
initial concentration: 0.1

metaid_0000034
constant: true
units: metaid_0000007
value: 0.7
name: KaB
type: Parameter

metaid_0000006
unit: 389838
unit: 389826
unit: 389813
name: flux
type: SBMLUnitsDef

metaid_0000024
constant: true
units: metaid_0000007
value: 0.05
name: KA
type: Parameter

390380
stoichiometry: 1.0
species: metaid_0000103
type: SpeciesReference

metaid_0000075
boundary condition: false
in compartment: metaid_0000095
name: Fgf
is: SBO:0000252
is version of: IPR017338
type: Species
initial concentration: 1.0
initial amount: NaN
constant: true
has only substance units: false

metaid_0000106
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.1
is: SBO:0000252
type: Species
in compartment: metaid_0000095
name: beta-catenin
initial amount: NaN
is version of: IPR013284

389765
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

390116
stoichiometry: 1.0
species: metaid_0000101
type: SpeciesReference

389971
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

metaid_0000112
constant: false
initial concentration: 0.1
is: SBO:0000252
boundary condition: false
is homolog to: Q16828
type: Species
initial amount: NaN
has only substance units: false
name: Dusp6 protein
in compartment: metaid_0000095

metaid_0000177
kinetic law: 390694
reactant: 390682
is version of: GO:0034261
fast: false
reversible: false
type: Reaction

389922
stoichiometry: 1.0
species: metaid_0000097
type: SpeciesReference

metaid_0000009
is: SBO:0000027
constant: true
units: metaid_0000007
value: 1.4
name: KdN
type: Parameter

390152
stoichiometry: 1.0
species: metaid_0000101
type: SpeciesReference

metaid_0000019
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.768
name: KdMF
type: Parameter

metaid_0000037
is: SBO:0000190
constant: true
units: dimensionless
value: 2.0
name: n
type: Parameter

metaid_0000162
kinetic law: 390104
reactant: 390092
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: false
type: Reaction

metaid_0000023
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.92
name: vmF
type: Parameter

390804
stoichiometry: 1.0
species: metaid_0000110
type: SpeciesReference

metaid_0000143
is: SBO:0000186
constant: true
units: metaid_0000006
value: 1.6
name: VMaX
type: Parameter

metaid_0000113
boundary condition: true
constant: false
name: inactive Ras
in compartment: metaid_0000095
is: SBO:0000252
initial concentration: NaN
type: Species
has only substance units: false
has version: IPR001806
initial amount: NaN
has version: CHEBI:17552

metaid_0000076
is: SBO:0000191
constant: true
units: metaid_0000007
value: 0.5
name: KaFgf
type: Parameter

metaid_0000103
has only substance units: false
in compartment: metaid_0000095
initial concentration: 0.001
boundary condition: false
constant: false
name: nuclear beta-catenin
is homolog to: P35222
initial amount: NaN
type: Species
is version of: IPR013284
is: SBO:0000252

389874
stoichiometry: 1.0
species: metaid_0000097
type: SpeciesReference

metaid_0000176
is version of: GO:0032856
kinetic law: 390670
type: Reaction
modifier: 390646
fast: false
product: 390633
is version of: REACT 2010.5
reversible: false
modifier: 390658

390416
stoichiometry: 1.0
species: metaid_0000102
type: SpeciesReference

metaid_0000161
kinetic law: 390080
modifier: 390068
product: 390055
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false
type: Reaction

metaid_0000036
constant: true
units: metaid_0000007
value: 0.48
name: Kmd
type: Parameter

metaid_0000022
is: SBO:0000186
constant: true
units: metaid_0000006
value: 3.0
name: vsF
type: Parameter

metaid_0000018
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.1
name: VdNan
type: Parameter

metaid_0000144
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.5
name: VMdX
type: Parameter

metaid_0000077
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.103
name: KaRas
type: Parameter

metaid_0000114
in compartment: metaid_0000095
is: SBO:0000252
is version of: IPR008349
type: Species
has only substance units: false
name: inactive ERK
initial amount: NaN
initial concentration: NaN
boundary condition: true
constant: false

metaid_0000104
is: SBO:0000252
name: Axin2 protein
is homolog to: Q9Y2T1
has only substance units: false
boundary condition: false
in compartment: metaid_0000095
initial concentration: 0.1
constant: false
initial amount: NaN
type: Species

metaid_0000175
kinetic law: 390621
reactant: 390609
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
type: Reaction

389777
exponent: -1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

390392
stoichiometry: 1.0
species: metaid_0000106
type: SpeciesReference

390512
stoichiometry: 1.0
species: metaid_0000107
type: SpeciesReference

metaid_0000098
in compartment: metaid_0000095
is: SBO:0000252
has only substance units: false
name: cytosolic NicD
initial amount: NaN
constant: false
is part of: IPR008297
boundary condition: false
type: Species
initial concentration: 0.2

metaid_0000164
kinetic law: 390164
reactant: 390152
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
type: Reaction

389862
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

390865
stoichiometry: 1.0
species: metaid_0000110
type: SpeciesReference

metaid_0000039
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.5
name: vMXa
type: Parameter

metaid_0000088
is: SBO:0000191
constant: true
units: dimensionless
value: 2.0
name: r
type: Parameter

metaid_0000029
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.087
name: vsB
type: Parameter

390200
stoichiometry: 1.0
species: metaid_0000105
type: SpeciesReference

metaid_0000174
kinetic law: 390597
modifier: 390584
product: 390572
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: false
type: Reaction

metaid_0000049
is: SBO:0000023
constant: true
units: metaid_0000005
value: 1.8
name: a1
type: Parameter

metaid_0000078
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.1
name: KdRas
type: Parameter

metaid_0000184
kinetic law: 390973
modifier: 390961
product: 390949
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: false
type: Reaction

metaid_0000109
has only substance units: false
is version of: IPR008349
initial amount: NaN
in compartment: metaid_0000095
boundary condition: false
initial concentration: 0.2
constant: false
type: Species
is: SBO:0000252
name: active ERK

389789
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000099
initial concentration: 0.0
name: nuclear NicD
in compartment: metaid_0000095
boundary condition: false
is: SBO:0000252
has only substance units: false
initial amount: NaN
constant: false
type: Species
is part of: IPR008297

metaid_0000136
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.9
name: VMsMDusp
type: Parameter

metaid_0000038
is: SBO:0000190
constant: true
units: dimensionless
value: 2.0
name: m
type: Parameter

metaid_0000163
kinetic law: 390140
modifier: 390128
product: 390116
is version of: GO:0006412
is: SBO:0000184
fast: false
reversible: false
type: Reaction

metaid_0000028
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.0
name: kd1
type: Parameter

390768
stoichiometry: 1.0
species: metaid_0000109
type: SpeciesReference

metaid_0000089
is: SBO:0000022
constant: true
units: metaid_0000004
value: 3.45
name: kc
type: Parameter

metaid_0000048
is: SBO:0000338
constant: true
units: metaid_0000004
value: 0.1
name: d1
type: Parameter

metaid_0000173
kinetic law: 390560
reactant: 390548
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: false
type: Reaction

metaid_0000079
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.05
name: KdErk
type: Parameter

389813
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000183
kinetic law: 390937
reactant: 390925
is version of: GO:0006402
is: SBO:0000179
fast: false
reversible: false
type: Reaction

metaid_0000058
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.5
name: KdDusp
type: Parameter

metaid_0000166
kinetic law: 390236
product: 390224
is version of: GO:0010467
fast: false
reversible: false
type: Reaction

metaid_0000137
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.5
name: VMdMDusp
type: Parameter

389850
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000086
is: SBO:0000027
constant: true
units: metaid_0000007
value: 0.5
name: KdMDusp
type: Parameter

metaid_0000027
is: SBO:0000022
constant: true
units: metaid_0000004
value: 0.3
name: ksF
type: Parameter

metaid_0000047
is homolog to: P49841
has only substance units: false
type: Species
initial concentration: 3.0
is: SBO:0000252
in compartment: metaid_0000095
initial amount: NaN
name: Kt
boundary condition: false
constant: true

390176
stoichiometry: 1.0
species: metaid_0000120
type: SpeciesReference

metaid_0000172
kinetic law: 390464
modifier: 390452
product: 390440
is version of: GO:0009299
is: SBO:0000183
fast: false
reversible: false
type: Reaction

390055
stoichiometry: 1.0
species: metaid_0000100
type: SpeciesReference

metaid_0000107
encodes: Q9Y2T1
initial concentration: 0.1
is version of: CHEBI:33699
in compartment: metaid_0000095
boundary condition: false
initial amount: NaN
is homolog to: ENSG00000168646
is: SBO:0000250
constant: false
name: Axin2 mRNA
type: Species
has only substance units: false

389838
exponent: -1.0
scale: 0
multipler: 60.0
kind: SECOND
type: SBMLUnit

390572
stoichiometry: 1.0
species: metaid_0000104
type: SpeciesReference

metaid_0000138
is: SBO:0000186
constant: true
units: metaid_0000006
value: 5.08
name: VMK
type: Parameter

metaid_0000165
reactant: 390176
fast: false
kinetic law: 390212
product: 390200
is: SBO:0000180
reversible: true
product: 390188
type: Reaction
is version of: GO:0043241

metaid_0000087
is: SBO:0000190
constant: true
units: dimensionless
value: 2.0
name: q
type: Parameter

metaid_0000170
kinetic law: 390404
product: 390392
reactant: 390380
is version of: GO:0006913
is: SBO:0000185
fast: false
reversible: true
type: Reaction

metaid_0000026
is: SBO:0000186
constant: true
units: metaid_0000006
value: 0.39
name: vdF
type: Parameter

metaid_0000067
is: SBO:0000022
constant: true
units: metaid_0000004
value: 1.35
name: kcDusp
type: Parameter

metaid_0000110
initial amount: NaN
type: Species
is version of: IPR006715
initial concentration: 0.1
boundary condition: false
constant: false
has only substance units: false
is: SBO:0000252
in compartment: metaid_0000095
name: active TF X

metaid_0000171
kinetic law: 390428
reactant: 390416
is version of: GO:0030163
is version of: REACT 11063.1
is: SBO:0000179
fast: false
reversible: false
type: Reaction

390925
stoichiometry: 1.0
species: metaid_0000111
type: SpeciesReference

metaid_0000108
type: Species
has version: IPR001806
is: SBO:0000252
initial concentration: 0.5
has version: CHEBI:15996
has only substance units: false
boundary condition: false
initial amount: NaN
in compartment: metaid_0000095
constant: false
name: active Ras

metaid_0000185
kinetic law: 390997
reactant: 390985
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: false
type: Reaction

metaid_0000120
constant: false
has only substance units: false
has part: Q9Y2T1
is: SBO:0000297
in compartment: metaid_0000095
type: Species
name: Axin2/Gsk3 destruction complex
boundary condition: true
initial amount: NaN
has part: P49841
initial concentration: NaN

ORG:
  orgname: University of Auckland
n:
  given: Catherine
  family: Lloyd

W3 CDTF: Wed Jun 05 18:17:15 BST 2013