311705
units: metaid_0000043
value: 55.0
name: r4
type: LocalParameter

440148
is: P18754
is encoded by: ENSG00000180198
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.7
initial amount: NaN
in compartment: 440048
type: Species

311828
stoichiometry: 1.0
species: 440348
type: SpeciesReference

311790
stoichiometry: 1.0
species: 440408
type: SpeciesReference

440488
kinetic law: 311546
product: 311534
product: 311522
reactant: 311510
is version of: GO:0005087
fast: false
reversible: true
type: Reaction

311558
units: metaid_0000043
value: 21.0
name: r2
type: LocalParameter

311582
stoichiometry: 1.0
species: 440188
type: SpeciesReference

311414
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

311378
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

311912
stoichiometry: 1.0
species: 440408
type: SpeciesReference

311330
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000043
unit: 311402
name: psec
type: SBMLUnitsDef

metaid_0000042
unit: 311390
unit: 311378
unit: 311366
name: pmicroMpsec
type: SBMLUnitsDef

311972
units: metaid_0000037
value: 0.1
name: Km
type: LocalParameter

metaid_0000037
unit: 311426
unit: 311414
name: microM
type: SBMLUnitsDef

440208
is: C00044
is: CHEBI:15996
constant: false
boundary condition: true
has only substance units: false
initial concentration: 500.0
initial amount: NaN
in compartment: 440048
type: Species

440088
has part: C00035
has part: P62826
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 440048
type: Species

440108
initial concentration: 0.0
has part: CHEBI:17552
has only substance units: false
constant: false
has part: C00035
boundary condition: false
has part: P62826
type: Species
in compartment: 440048
has part: P18754
initial amount: NaN

440128
is: C00035
is: CHEBI:17552
constant: false
boundary condition: true
has only substance units: false
initial concentration: 1.6
initial amount: NaN
in compartment: 440048
type: Species

440068
is: GO:0005737
constant: true
size: 1.8E-11
spatial dimensions: 3.0
type: Compartment

311840
stoichiometry: 1.0
species: 440328
type: SpeciesReference

311766
units: metaid_0000043
value: 0.03
name: kpermRanGTP
type: LocalParameter

311498
units: metaid_0000043
value: 55.0
name: r8
type: LocalParameter

440048
is: GO:0005634
constant: true
size: 1.2E-11
spatial dimensions: 3.0
type: Compartment

312034
units: metaid_0000043
value: 10.6
name: kcat
type: LocalParameter

311426
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

311669
stoichiometry: 1.0
species: 440228
type: SpeciesReference

metaid_0000041
unit: 311354
unit: 311342
unit: 311330
name: microMpsec
type: SBMLUnitsDef

311900
stoichiometry: 1.0
species: 440368
type: SpeciesReference

311632
units: metaid_0000042
value: 0.6
name: r3
type: LocalParameter

311462
stoichiometry: 1.0
species: 440108
type: SpeciesReference

440508
kinetic law: 311620
product: 311607
reactant: 311594
reactant: 311582
is version of: GO:0005525
fast: false
reversible: true
type: Reaction

440328
is: P43487
is version of: IPR000156
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.0
initial amount: NaN
in compartment: 440068
type: Species

311402
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

440528
kinetic law: 311693
product: 311681
product: 311669
reactant: 311657
is version of: GO:0043241
fast: false
reversible: true
type: Reaction

311888
units: metaid_0000043
value: 4.0E-4
name: koff
type: LocalParameter

311594
stoichiometry: 1.0
species: 440208
type: SpeciesReference

311366
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

440548
kinetic law: 311754
product: 311742
reactant: 311730
is version of: GO:0006913
fast: false
reversible: true
type: Reaction

311390
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

311984
stoichiometry: 1.0
species: 440348
type: SpeciesReference

311924
stoichiometry: 1.0
species: 440328
type: SpeciesReference

311852
stoichiometry: 1.0
species: 440368
type: SpeciesReference

440168
has only substance units: false
initial amount: NaN
in compartment: 440048
constant: false
has part: C00044
has part: P18754
initial concentration: 0.0
has part: P62826
boundary condition: false
has part: CHEBI:15996
type: Species

440188
has part: P62826
has part: P18754
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 440048
type: Species

311450
stoichiometry: 1.0
species: 440148
type: SpeciesReference

311607
stoichiometry: 1.0
species: 440168
type: SpeciesReference

311534
stoichiometry: 1.0
species: 440128
type: SpeciesReference

311438
stoichiometry: 1.0
species: 440088
type: SpeciesReference

312046
units: metaid_0000037
value: 0.7
name: Km
type: LocalParameter

440568
kinetic law: 311803
product: 311790
reactant: 311778
is version of: GO:0006913
fast: false
reversible: true
type: Reaction

440630
product: 311924
kinetic law: 311948
type: Reaction
reactant: 311900
name: RanBP1_RanGDP
product: 311912
is version of: GO:0043241
modifier: 311936
reversible: true
fast: false

BIOMD0000000192
volume units: metaid_0000004
reaction: 440668
species: 440368
species: 440168
name: Görlich2003_RanGTP_gradient
reaction: 440548
compartment: 440068
length unit: length
is: MODEL4969417017
reaction: 440528
units def: metaid_0000041
type: SBMLModel
curated: true
species: 440188
creator:
  ORG:
    orgname: EMBL-EBI
  n:
    given: Vijayalakshmi
    family: Chelliah
substance units: metaid_0000040
created:
  W3 CDTF: Tue Sep 09 15:04:34 BST 2008
species: 440408
notes: This model represents a concentration gradient of RanGTP across the nuclear envelope. This gradient is generated by distribution of regulators of RanGTPase. We have taken a log linear plot of graphs generated by GENESIS and compared with the experimental graphs. This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2008 The BioModels Team. For more information see the terms of use .
area units: metaid_0000005
species: 440228
species: 440108
is part of: REACT 9507
reaction: 440488
units def: metaid_0000037
species: 440208
modified:
  W3 CDTF: Wed Dec 01 22:10:54 GMT 2010
reaction: 440628
species: 440128
reaction: 440508
time units: metaid_0000008
species: 440088
creator:
  ORG:
    orgname: ZMBH, INF 282, Heidelberg
  n:
    given: Dirk
    family: Gorlich
species: 440328
units def: metaid_0000040
reaction: 440568
creator:
  ORG:
    orgname: EMBL-EBI
  n:
    given: Lukas
    family: Endler
compartment: 440048
species: 440268
is version of: GO:0008536
reaction: 440630
reaction: 440468
species: 440148
units def: metaid_0000042
units def: metaid_0000043
occurs in: http://identifiers.org/taxonomy/9606
species: 440348
is described by: http://identifiers.org/pubmed/12606574

311486
units: metaid_0000042
value: 74.0
name: r1
type: LocalParameter

440668
kinetic law: 312021
modifier: 312009
product: 311996
reactant: 311984
is version of: GO:0032860
fast: false
reversible: true
name: RanGAP_RanGDP
type: Reaction

311876
units: metaid_0000042
value: 0.3
name: kon
type: LocalParameter

311645
units: metaid_0000043
value: 19.0
name: r6
type: LocalParameter

311354
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

311522
stoichiometry: 1.0
species: 440188
type: SpeciesReference

311742
stoichiometry: 1.0
species: 440348
type: SpeciesReference

311718
units: metaid_0000042
value: 100.0
name: r5
type: LocalParameter

311960
units: metaid_0000043
value: 10.8
name: kcat
type: LocalParameter

440468
kinetic law: 311474
product: 311462
reactant: 311450
reactant: 311438
is version of: GO:0006461
fast: false
reversible: true
type: Reaction

311318
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

311570
units: metaid_0000042
value: 11.0
name: r7
type: LocalParameter

440348
has part: C00044
has part: P62826
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 440068
type: Species

311778
stoichiometry: 1.0
species: 440088
type: SpeciesReference

311815
units: metaid_0000043
value: 0.12
name: kpermRanGDP
type: LocalParameter

311657
stoichiometry: 1.0
species: 440168
type: SpeciesReference

311510
stoichiometry: 1.0
species: 440108
type: SpeciesReference

311996
stoichiometry: 1.0
species: 440408
type: SpeciesReference

311342
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

440408
has part: C00035
has part: P62826
constant: false
boundary condition: false
has only substance units: false
initial concentration: 5.0
initial amount: NaN
in compartment: 440068
type: Species

440228
has part: C00044
has part: P62826
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 440048
type: Species

311681
stoichiometry: 1.0
species: 440148
type: SpeciesReference

440268
is: P46060
is version of: IPR000331
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.7
initial amount: NaN
in compartment: 440068
type: Species

311730
stoichiometry: 1.0
species: 440228
type: SpeciesReference

440368
has part: P43487
initial concentration: 0.0
has only substance units: false
has part: P62826
constant: false
initial amount: NaN
type: Species
has part: C00044
in compartment: 440068
boundary condition: false

440628
kinetic law: 311864
product: 311852
reactant: 311840
reactant: 311828
is version of: GO:0006461
fast: false
reversible: true
type: Reaction