metaid_0000007
constant: true
units: dimensionless
value: 2.02
type: Parameter

metaid_0000003
constant: true
units: metaid_0000031
value: 0.05
type: Parameter

metaid_0000027
kinetic law: 109720
modifier: 109708
product: 109696
is part of: GO:0032957
is version of: GO:0004435
fast: false
reversible: false
name: PLC
type: Reaction

metaid_0000013
constant: true
units: metaid_0000032
value: 0.5
type: Parameter

metaid_0000017
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: Cytoplasm
type: Compartment

109660
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

109516
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000033
is: GO:0005783
constant: true
size: 1.0
spatial dimensions: 3.0
name: Endoplasmic Reticulum
type: Compartment

109576
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000023
kinetic law: 109564
reactant: 109552
is version of: GO:0051481
fast: false
reversible: false
name: Calcium export from cell
type: Reaction

metaid_0000006
constant: true
units: metaid_0000030
value: 0.15
type: Parameter

109696
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

metaid_0000012
constant: true
units: metaid_0000030
value: 0.1
type: Parameter

109492
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

109468
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000016
constant: true
units: metaid_0000032
value: 0.08
type: Parameter

metaid_0000032
unit: 109516
name: sec_1
type: SBMLUnitsDef

metaid_0000026
kinetic law: 109684
product: 109672
reactant: 109660
is version of: GO:0007204
is version of: GO:0022840
fast: false
reversible: false
name: Leak flux
type: Reaction

109624
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000022
kinetic law: 109540
product: 109528
is version of: GO:0006816
is version of: GO:0007204
fast: false
reversible: false
name: vin
type: Reaction

109444
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000011
constant: true
units: metaid_0000031
value: 15.0
type: Parameter

metaid_0000005
constant: true
units: metaid_0000032
value: 40.0
type: Parameter

metaid_0000009
constant: true
units: dimensionless
value: 2.2
type: Parameter

metaid_0000019
initial amount: NaN
is: C00076
has only substance units: false
boundary condition: false
initial concentration: 0.1
in compartment: metaid_0000017
type: Species
name: Cytoplasmic Calcium
constant: false
is: CHEBI:29108

metaid_0000015
constant: true
units: metaid_0000030
value: 0.3
type: Parameter

109588
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000030
unit: 109468
unit: 109456
name: uM
type: SBMLUnitsDef

metaid_0000025
kinetic law: 109648
product: 109636
reactant: 109624
is version of: GO:0005388
fast: false
reversible: false
name: serca
type: Reaction

BIOMD0000000184
is: MODEL9223106020
parameter: metaid_0000004
parameter: metaid_0000015
reaction: metaid_0000028
curated: true
parameter: metaid_0000009
volume units: metaid_0000004
occurs in: http://identifiers.org/taxonomy/40674
parameter: metaid_0000016
compartment: metaid_0000017
units def: metaid_0000030
parameter: metaid_0000007
modified:
  W3 CDTF: Wed Jul 11 18:45:28 BST 2012
parameter: metaid_0000006
units def: metaid_0000032
species: metaid_0000019
parameter: metaid_0000012
compartment: metaid_0000033
reaction: metaid_0000023
units def: metaid_0000029
creator:
  ORG:
    orgname: EMBL-EBI
  n:
    given: Lukas
    family: Endler
parameter: metaid_0000003
type: SBMLModel
parameter: metaid_0000008
has part: GO:0019722
is described by: http://identifiers.org/pubmed/18275973
species: metaid_0000021
parameter: metaid_0000010
reaction: metaid_0000025
reaction: metaid_0000024
area units: metaid_0000005
units def: metaid_0000031
parameter: metaid_0000013
parameter: metaid_0000014
reaction: metaid_0000022
time units: metaid_0000055
parameter: metaid_0000011
reaction: metaid_0000027
created:
  W3 CDTF: Thu Aug 21 12:36:22 BST 2008
substance units: metaid_0000029
species: metaid_0000020
parameter: metaid_0000005
notes: The model reproduces the time profile of cytoplasmic Calcium as depicted in Fig 3 of the paper. Model successfully reproduced using Jarnac and MathSBML. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
creator:
  ORG:
    orgname: California Institute of Technology
  n:
    given: Harish
    family: Dharuri
length unit: length
name: Lavrentovich2008_Ca_Oscillations
reaction: metaid_0000026

109672
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000029
unit: 109444
name: micro mole
type: SBMLUnitsDef

109732
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

109504
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000021
is: C01245
name: IP3
initial concentration: 0.1
in compartment: metaid_0000017
has only substance units: false
constant: false
is: CHEBI:16595
initial amount: NaN
type: Species
boundary condition: false

109552
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

109636
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

109480
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000010
constant: true
units: metaid_0000030
value: 0.1
type: Parameter

109456
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000031
unit: 109504
unit: 109492
unit: 109480
name: uM_sec_1
type: SBMLUnitsDef

109528
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000008
constant: true
units: metaid_0000030
value: 0.15
type: Parameter

metaid_0000014
constant: true
units: metaid_0000031
value: 0.05
type: Parameter

metaid_0000024
kinetic law: 109612
modifier: 109600
product: 109588
reactant: 109576
is version of: GO:0048763
fast: false
reversible: false
name: CICR
type: Reaction

metaid_0000028
kinetic law: 109744
reactant: 109732
fast: false
reversible: false
name: IP3 degradation
type: Reaction

metaid_0000004
constant: true
units: metaid_0000032
value: 0.5
type: Parameter

metaid_0000020
initial concentration: 1.5
in compartment: metaid_0000033
constant: false
initial amount: NaN
name: Calcium in ER
type: Species
is: C00076
boundary condition: false
has only substance units: false
is: CHEBI:29108