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W3 CDTF: Thu Jul 05 15:50:40 BST 2012

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ORG:
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n:
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metaid_0000092
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225501
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224279
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225597
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metaid_0000072
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metaid_0000093
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BIOMD0000000165
type: SBMLModel
species: metaid_0000031
rule: metaid_0000101
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notes: The model reproduces Fig 2B of the paper. Model successfully tested on MathSBML To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
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225236
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metaid_0000080
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225393
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225585
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metaid_0000070
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225080
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224801
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metaid_0000091
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metaid_0000081
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225573
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224473
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type: Parameter

224219
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

metaid_0000096
kinetic law: 225429
product: 225417
product: 225405
reactant: 225393
fast: false
reversible: true
name: AKARp_dephosph
type: Reaction

metaid_0000057
is version of: Q5T5Y4
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: b1AR_p
type: Species

metaid_0000043
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: Propranolol
type: Species

223491
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

223647
exponent: 1.0
scale: 0
multipler: 1000.0
kind: DIMENSIONLESS
type: SBMLUnit

metaid_0000059
constant: false
boundary condition: false
has only substance units: false
initial concentration: 10.0
initial amount: NaN
in compartment: metaid_0000026
name: AKAR
type: Species

225525
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

225356
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

225621
units: metaid_0000011
value: 5.0
type: LocalParameter

224255
units: metaid_0000012
value: 1000.0
type: LocalParameter

metaid_0000083
kinetic law: 224569
product: 224557
reactant: 224545
reactant: 224533
fast: false
reversible: true
name: bind_AKARp_PP
type: Reaction

224704
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

metaid_0000105
constant: false
value: 0.0
type: Parameter

224557
stoichiometry: 1.0
species: metaid_0000062
type: SpeciesReference

metaid_0000097
kinetic law: 225489
product: 225477
product: 225465
reactant: 225453
fast: false
reversible: true
name: AKAR_phosph
type: Reaction

225284
stoichiometry: 1.0
species: metaid_0000040
type: SpeciesReference

metaid_0000058
has part: Q5T5Y4
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: L_b1AR
type: Species

metaid_0000056
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: FskAC
type: Species

metaid_0000042
has part: P17612
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: PKAC_AKAR
type: Species

224594
units: metaid_0000011
value: 7000.0
type: LocalParameter

223575
exponent: 1.0
scale: 0
multipler: 1.0
kind: MOLE
type: SBMLUnit

224024
stoichiometry: 1.0
species: metaid_0000064
type: SpeciesReference

metaid_0000019
constant: true
units: metaid_0000013
value: 0.0
type: Parameter

224618
stoichiometry: 1.0
species: metaid_0000057
type: SpeciesReference

224207
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

224995
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000084
modifier: 224642
modifier: 224655
product: 224618
name: desens_pka
fast: false
modifier: 224630
type: Reaction
reversible: true
reactant: 224606
kinetic law: 224668

223479
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

223539
exponent: 2.0
scale: -6
multipler: 1.0
kind: METRE
type: SBMLUnit

223707
stoichiometry: 1.0
species: metaid_0000035
type: SpeciesReference

metaid_0000094
kinetic law: 225308
product: 225296
reactant: 225284
reactant: 225272
fast: false
reversible: true
name: bind_PKAC_AKAR
type: Reaction

metaid_0000104
constant: true
value: 1.0
type: Parameter

223938
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

224060
units: metaid_0000011
value: 62.0
type: LocalParameter

metaid_0000055
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: Fsk
type: Species

224267
units: metaid_0000011
value: 33000.0
type: LocalParameter

metaid_0000045
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: light_spot
type: Species

225344
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

223659
exponent: 3.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

225537
stoichiometry: 1.0
species: metaid_0000028
type: SpeciesReference

224545
stoichiometry: 1.0
species: metaid_0000060
type: SpeciesReference

224851
stoichiometry: 1.0
species: metaid_0000038
type: SpeciesReference

225007
stoichiometry: 1.0
species: metaid_0000051
type: SpeciesReference

metaid_0000085
kinetic law: 224741
product: 224729
reactant: 224716
reactant: 224704
is version of: GO:0004939
fast: false
reversible: true
name: bind_L_b1ARGs
type: Reaction

225272
stoichiometry: 1.0
species: metaid_0000059
type: SpeciesReference

metaid_0000095
kinetic law: 225381
product: 225369
reactant: 225356
reactant: 225344
fast: false
reversible: true
name: inhibit_PDE
type: Reaction

metaid_0000103
constant: true
value: 1.0
type: Parameter

224606
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

224231
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

224012
stoichiometry: 1.0
species: metaid_0000058
type: SpeciesReference

metaid_0000044
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: b1ARinhib
type: Species

metaid_0000054
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000026
name: PDE_IBMX
type: Species

223563
exponent: -3.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

224582
units: metaid_0000012
value: 1000.0
type: LocalParameter

224680
units: metaid_0000012
value: 0.0036
type: LocalParameter

W3 CDTF: Wed Oct 03 11:05:51 BST 2007