metaid_0000032
constant: false
value: 0.92
type: Parameter

metaid_0000003
constant: true
value: 2.55
type: Parameter

665012
persistant: true
initial value: true
type: Trigger

metaid_0000022
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: precursor Mdm2
type: Species

metaid_0000007
constant: true
value: 0.85
type: Parameter

metaid_0000013
kinetic law: 664795
product: 664783
is version of: GO:0006412
fast: false
reversible: false
name: p53 production
type: Reaction

664783
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

metaid_0000023
constant: true
value: 55.0
type: Parameter

664867
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

metaid_0000035
event assignment: 665049
event assignment: 665037
event assignment: 665025
trigger: 665012
use values from trigger time: true
type: Event

metaid_0000031
constant: true
value: 34.0
type: Parameter

664904
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

metaid_0000004
constant: true
value: 1.0
type: Parameter

664771
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

metaid_0000014
kinetic law: 664819
reactant: 664807
is version of: GO:0042176
fast: false
reversible: false
name: Mdm2 independent p53 degradation
type: Reaction

metaid_0000018
kinetic law: 664928
product: 664915
reactant: 664904
is version of: GO:0006412
fast: false
reversible: false
name: Mdm2 synthesis from precursor
type: Reaction

metaid_0000008
constant: true
value: 0.6
type: Parameter

metaid_0000028
constant: false
value: 0.0
type: Parameter

metaid_0000024
kinetic law: 664952
reactant: 664939
is version of: GO:0044257
fast: false
reversible: true
name: Mdm2 degradation
type: Reaction

BIOMD0000000158
reaction: metaid_0000014
parameter: metaid_0000005
reaction: metaid_0000024
length unit: length
units def: metaid_0000020
name: Zatorsky2006_p53_Model2
parameter: metaid_0000025
is part of: GO:0042771
type: SBMLModel
parameter: metaid_0000008
parameter: metaid_0000032
reaction: metaid_0000018
units def: metaid_0000019
species: metaid_0000011
parameter: metaid_0000029
modified:
  W3 CDTF: Thu Jul 05 15:41:12 BST 2012
occurs in: http://identifiers.org/taxonomy/9606
reaction: metaid_0000015
compartment: metaid_0000009
event: metaid_0000034
parameter: metaid_0000006
rule: metaid_0000027
parameter: metaid_0000030
created:
  W3 CDTF: Thu Jan 10 17:38:04 GMT 2008
is part of: hsa04115
is: MODEL0076306022
parameter: metaid_0000023
parameter: metaid_0000033
reaction: metaid_0000016
substance units: metaid_0000019
parameter: metaid_0000003
creator:
  ORG:
    orgname: California Institute of Technology
  n:
    given: Harish
    family: Dharuri
is described by: http://identifiers.org/pubmed/16773083
reaction: metaid_0000013
parameter: metaid_0000004
curated: true
event: metaid_0000035
volume units: metaid_0000084
notes: The model reproduces time profile of p53 and Mdm2 as depicted in Fig 6B of the paper for Model 2. Results obtained using MathSBML. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
parameter: metaid_0000007
time units: metaid_0000020
area units: metaid_0000005
species: metaid_0000012
parameter: metaid_0000031
parameter: metaid_0000028
species: metaid_0000022

664760
exponent: 1.0
scale: 0
multipler: 1.0
kind: ITEM
type: SBMLUnit

metaid_0000034
event assignment: 664999
event assignment: 664988
event assignment: 664975
trigger: 664963
use values from trigger time: true
type: Event

664807
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

664831
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

metaid_0000030
constant: false
value: 1.0
type: Parameter

metaid_0000005
constant: true
value: 0.0
type: Parameter

metaid_0000019
unit: 664760
name: dimensionless
type: SBMLUnitsDef

metaid_0000020
unit: 664771
name: hours
type: SBMLUnitsDef

metaid_0000015
kinetic law: 664856
modifier: 664843
reactant: 664831
is version of: GO:0042176
fast: false
reversible: false
name: Mdm2 dependent p53 degradation
type: Reaction

metaid_0000009
is: GO:0005623
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

metaid_0000011
is version of: P04637
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.28
initial amount: NaN
in compartment: metaid_0000009
name: p53
type: Species

metaid_0000025
constant: false
value: 0.0
type: Parameter

metaid_0000029
constant: false
value: 0.0
type: Parameter

664963
persistant: true
initial value: true
type: Trigger

metaid_0000033
constant: false
value: 0.12
type: Parameter

664939
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

metaid_0000006
constant: true
value: 3.15
type: Parameter

metaid_0000016
kinetic law: 664891
modifier: 664880
product: 664867
is version of: GO:0006351
fast: false
reversible: false
name: p53 dependent Mdm2 precursor production
type: Reaction

metaid_0000012
is version of: Q00987
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.73
initial amount: NaN
in compartment: metaid_0000009
name: Mdm2
type: Species

664915
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference