204873
stoichiometry: 1.0
species: metaid_0000074
type: SpeciesReference

206089
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

206921
stoichiometry: 1.0
species: metaid_0000123
type: SpeciesReference

211477
persistant: true
initial value: true
type: Trigger

205546
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

206981
stoichiometry: 1.0
species: metaid_0000123
type: SpeciesReference

203429
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

202360
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

metaid_0000224
kinetic law: 210993
product: 210981
reactant: 210969
reactant: 210957
fast: false
reversible: false
name: PP2A_Ca_binding
type: Reaction

209199
stoichiometry: 1.0
species: metaid_0000183
type: SpeciesReference

204439
value: 3.0
name: kcat11
type: LocalParameter

203741
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

208366
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

210234
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

211356
value: 5.0
name: kcat56
type: LocalParameter

metaid_0000223
kinetic law: 210933
product: 210921
product: 210909
reactant: 210897
fast: false
reversible: false
name: D75_PP2APCa_unbinding
type: Reaction

205860
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

203213
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

203573
stoichiometry: 1.0
species: metaid_0000047
type: SpeciesReference

208668
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

metaid_0000249
event assignment: 211690
trigger: 211678
use values from trigger time: true
name: ca_on9
type: Event

202624
value: 12.0
name: koff2
type: LocalParameter

metaid_0000189
kinetic law: 209487
product: 209475
reactant: 209463
fast: false
reversible: false
name: Ca_destroy
type: Reaction

210585
value: 10.0
name: koff50
type: LocalParameter

209125
stoichiometry: 1.0
species: metaid_0000180
type: SpeciesReference

207222
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

211248
value: 200000.0
name: kon56
type: LocalParameter

211825
persistant: true
initial value: true
type: Trigger

metaid_0000222
kinetic law: 210873
product: 210861
product: 210849
reactant: 210837
fast: false
reversible: false
name: D75_dephospho_by_PP2APCa_on_75
type: Reaction

205462
value: 75000.0
name: kon19
type: LocalParameter

210801
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

209872
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

205378
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

204632
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

210765
value: 24.0
name: kcat53
type: LocalParameter

202576
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

metaid_0000188
kinetic law: 209451
product: 209439
reactant: 209427
fast: false
reversible: false
name: Ca_in
type: Reaction

207161
stoichiometry: 1.0
species: metaid_0000126
type: SpeciesReference

207560
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

203090
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

207825
stoichiometry: 1.0
species: metaid_0000145
type: SpeciesReference

metaid_0000221
kinetic law: 210813
product: 210801
product: 210789
reactant: 210777
fast: false
reversible: false
name: D75:137_PP2APCa_unbinding
type: Reaction

211776
persistant: true
initial value: true
type: Trigger

204415
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

205522
value: 0.03
name: kcat19
type: LocalParameter

211453
persistant: true
initial value: true
type: Trigger

209391
stoichiometry: 1.0
species: metaid_0000145
type: SpeciesReference

209175
value: 40.0
name: koff44
type: LocalParameter

metaid_0000200
has part: CHEBI:29108
boundary condition: false
initial concentration: 0.0
initial amount: NaN
constant: false
has part: IPR006186
in compartment: metaid_0000003
has only substance units: false
name: D75_PP2ACa
has part: Q9UD71
type: Species

211164
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000220
kinetic law: 210753
product: 210741
product: 210729
reactant: 210717
fast: false
reversible: false
name: D75:137_dephospho_by_PP2APCa_on_75
type: Reaction

206391
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

206065
value: 10.0
name: kcat22
type: LocalParameter

metaid_0000187
kinetic law: 209403
product: 209391
product: 209379
reactant: 209367
fast: false
reversible: false
name: cAMP_PDEP_degradation
type: Reaction

210957
stoichiometry: 1.0
species: metaid_0000154
type: SpeciesReference

205884
value: 10.0
name: kcat15
type: LocalParameter

203237
value: 12.0
name: koff5
type: LocalParameter

202384
value: 5600000.0
name: kon1
type: LocalParameter

204692
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

metaid_0000186
kinetic law: 209343
product: 209331
product: 209319
reactant: 209307
fast: false
reversible: false
name: cAMP_PDEP_unbinding
type: Reaction

206439
stoichiometry: 1.0
species: metaid_0000111
type: SpeciesReference

210561
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

211224
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

211801
persistant: true
initial value: true
type: Trigger

208644
stoichiometry: 1.0
species: metaid_0000164
type: SpeciesReference

metaid_0000185
has only substance units: false
has part: CHEBI:17489
has part: IPR000396
in compartment: metaid_0000003
initial concentration: 0.0
initial amount: NaN
constant: false
boundary condition: false
type: Species
name: cAMP_PDEP

207247
stoichiometry: 1.0
species: metaid_0000133
type: SpeciesReference

206643
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

206727
value: 24.0
name: kcat26
type: LocalParameter

202648
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

207584
value: 6.0
name: kcat29
type: LocalParameter

207185
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

211752
persistant: true
initial value: true
type: Trigger

203012
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

209065
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

203657
value: 1.7E7
name: kon10
type: LocalParameter

203959
value: 10.0
name: kcat9
type: LocalParameter

207535
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

202420
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

204343
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

209896
stoichiometry: 1.0
species: metaid_0000200
type: SpeciesReference

metaid_0000184
kinetic law: 209283
product: 209271
reactant: 209259
reactant: 209247
fast: false
reversible: false
name: cAMP_PDEP_binding
type: Reaction

204656
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

204043
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

208210
value: 3.0E15
name: kon36
type: LocalParameter

209331
stoichiometry: 1.0
species: metaid_0000145
type: SpeciesReference

210789
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

metaid_0000162
boundary condition: false
initial amount: NaN
type: Species
has part: PIRSF000548
in compartment: metaid_0000003
has only substance units: false
name: cAMP_R2C2
initial concentration: 0.0
constant: false
has part: PIRSF000582
has part: CHEBI:17489

208294
stoichiometry: 1.0
species: metaid_0000155
type: SpeciesReference

metaid_0000243
event assignment: 211542
trigger: 211529
use values from trigger time: true
name: Ca_on3
type: Event

208571
value: 7.5E7
name: kon40
type: LocalParameter

metaid_0000183
is: CHEBI:16027
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: AMP
type: Species

metaid_0000047
constant: false
initial concentration: 0.0
boundary condition: false
name: D75_PP2A
has part: IPR006186
type: Species
in compartment: metaid_0000003
has part: Q9UD71
has only substance units: false
initial amount: NaN

202950
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000204
kinetic law: 210089
product: 210077
product: 210065
reactant: 210053
fast: false
reversible: false
name: D75:137_PP2ACa_unbinding
type: Reaction

metaid_0000027
kinetic law: 202975
product: 202963
reactant: 202950
reactant: 202938
fast: false
reversible: false
name: D34_CK1_binding
type: Reaction

206571
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000142
kinetic law: 207680
product: 207668
reactant: 207656
reactant: 207644
fast: false
reversible: false
name: PDE_PKA_binding
type: Reaction

206909
value: 7500000.0
name: kon20
type: LocalParameter

202684
value: 3.0
name: kcat2
type: LocalParameter

208933
value: 60.0
name: koff41
type: LocalParameter

205679
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

metaid_0000163
kinetic law: 208438
product: 208426
reactant: 208414
reactant: 208402
fast: false
reversible: false
name: cAMP_R2C2_binding_by_cAMP
type: Reaction

211581
persistant: true
initial value: true
type: Trigger

metaid_0000244
event assignment: 211568
trigger: 211555
use values from trigger time: true
name: ca_on4
type: Event

208908
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000182
kinetic law: 209223
product: 209211
product: 209199
reactant: 209187
fast: false
reversible: false
name: cAMP_PDE_degradation
type: Reaction

metaid_0000048
kinetic law: 203645
product: 203633
reactant: 203621
reactant: 203609
fast: false
reversible: false
name: D75_PP2AP_binding
type: Reaction

205920
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000028
initial concentration: 0.0
has only substance units: false
constant: false
name: D34_CK1
type: Species
has part: Q9UD71
boundary condition: false
in compartment: metaid_0000003
has part: Q99PS2
initial amount: NaN

metaid_0000203
kinetic law: 210029
product: 210017
product: 210005
reactant: 209993
fast: false
reversible: false
name: D75:137_dephospho_by_PP2ACa_on_75
type: Reaction

metaid_0000143
has only substance units: false
has part: IPR000396
has part: PIRSF000582
name: PDE_PKA
initial concentration: 0.0
type: Species
constant: false
in compartment: metaid_0000003
initial amount: NaN
boundary condition: false

206969
value: 3.0
name: kcat20
type: LocalParameter

205618
stoichiometry: 1.0
species: metaid_0000094
type: SpeciesReference

203393
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

metaid_0000241
event assignment: 211465
trigger: 211453
use values from trigger time: true
name: ca_on1
type: Event

205042
value: 3.0
name: kcat18
type: LocalParameter

204716
stoichiometry: 1.0
species: metaid_0000074
type: SpeciesReference

202444
value: 12.0
name: koff1
type: LocalParameter

metaid_0000160
boundary condition: false
type: Species
has only substance units: false
has part: PIRSF000548
initial amount: NaN
in compartment: metaid_0000003
has part: PIRSF000582
name: R2C2
constant: false
initial concentration: 6.64E-6

metaid_0000029
initial amount: NaN
has only substance units: false
initial concentration: 0.0
in compartment: metaid_0000003
type: Species
has part: CHEBI:29108
boundary condition: false
constant: false
has part: PIRSF000911
name: PP2B

208234
stoichiometry: 1.0
species: metaid_0000128
type: SpeciesReference

metaid_0000181
kinetic law: 209162
product: 209150
product: 209137
reactant: 209125
fast: false
reversible: false
name: cAMP_PDE_unbinding
type: Reaction

209740
value: 6.0
name: koff47
type: LocalParameter

metaid_0000049
is version of: IPR006186
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: PP2AP
type: Species

206210
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

metaid_0000202
has part: Q9UD71
constant: false
in compartment: metaid_0000003
has part: CHEBI:29108
boundary condition: false
initial concentration: 0.0
type: Species
has only substance units: false
has part: IPR006186
initial amount: NaN
name: D75:137_PP2ACa

203633
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

209089
stoichiometry: 1.0
species: metaid_0000180
type: SpeciesReference

203935
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

207692
value: 6000000.0
name: kon31
type: LocalParameter

metaid_0000140
kinetic law: 207572
product: 207560
product: 207548
reactant: 207535
fast: false
reversible: false
name: CK1P_dephospho_by_PP2B
type: Reaction

metaid_0000242
event assignment: 211490
trigger: 211477
use values from trigger time: true
name: ca_on2
type: Event

208872
value: 1.8E7
name: kon41
type: LocalParameter

202756
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000161
is: CHEBI:17489
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: cAMP
type: Species

metaid_0000180
boundary condition: false
has part: IPR000396
constant: false
name: cAMP_PDE
has part: CHEBI:17489
has only substance units: false
type: Species
in compartment: metaid_0000003
initial amount: NaN
initial concentration: 0.0

208534
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

210345
value: 1.7E7
name: kon51
type: LocalParameter

metaid_0000229
kinetic law: 211236
product: 211224
reactant: 211212
reactant: 211200
fast: false
reversible: false
name: PP2AP_Ca_binding
type: Reaction

209800
value: 10.0
name: kcat46
type: LocalParameter

204451
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

207644
stoichiometry: 1.0
species: metaid_0000127
type: SpeciesReference

metaid_0000201
kinetic law: 209969
product: 209956
reactant: 209944
reactant: 209932
fast: false
reversible: false
name: D75:137_PP2ACa_binding
type: Reaction

205282
value: 1.0E7
name: kon17
type: LocalParameter

metaid_0000141
kinetic law: 207620
product: 207608
reactant: 207596
fast: false
reversible: false
name: CK1_phosphorylation
type: Reaction

metaid_0000208
has part: Q9UD71
boundary condition: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
has only substance units: false
type: Species
name: D34:75_PP2APCa
has part: CHEBI:29108
has part: IPR006186
constant: false

metaid_0000166
name: cAMP4_R2C2
in compartment: metaid_0000003
has only substance units: false
type: Species
has part: PIRSF000548
initial amount: NaN
has part: CHEBI:17489
initial concentration: 0.0
has part: PIRSF000582
boundary condition: false
constant: false

204921
value: 12.0
name: koff14
type: LocalParameter

209319
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

202660
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000247
event assignment: 211642
trigger: 211630
use values from trigger time: true
name: ca_on7
type: Event

205655
stoichiometry: 1.0
species: metaid_0000094
type: SpeciesReference

208957
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

208342
stoichiometry: 1.0
species: metaid_0000160
type: SpeciesReference

206198
stoichiometry: 1.0
species: metaid_0000107
type: SpeciesReference

210258
stoichiometry: 1.0
species: metaid_0000208
type: SpeciesReference

205956
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

206307
value: 24.0
name: koff25
type: LocalParameter

208270
value: 1.0
name: koff35
type: LocalParameter

metaid_0000228
kinetic law: 211176
product: 211164
product: 211151
reactant: 211139
fast: false
reversible: false
name: PP2ACa_phospho_by_PKA
type: Reaction

metaid_0000023
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: D34
type: Species

204560
value: 2.7
name: kcat12
type: LocalParameter

metaid_0000167
kinetic law: 208498
product: 208486
reactant: 208474
reactant: 208462
fast: false
reversible: false
name: cAMP2_R2C2_binding_by_cAMP
type: Reaction

208306
stoichiometry: 2.0
species: metaid_0000154
type: SpeciesReference

metaid_0000207
kinetic law: 210272
product: 210258
reactant: 210246
reactant: 210234
fast: false
reversible: false
name: D34:75_PP2APCa_binding
type: Reaction

211030
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

206945
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

203077
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000248
event assignment: 211666
trigger: 211654
use values from trigger time: true
name: ca_on8
type: Event

metaid_0000024
kinetic law: 202853
product: 202841
product: 202829
reactant: 202817
fast: false
reversible: false
name: D_Phospho_by_PKA_on_34
type: Reaction

209956
stoichiometry: 1.0
species: metaid_0000202
type: SpeciesReference

metaid_0000227
has part: CHEBI:29108
has only substance units: false
initial concentration: 0.0
initial amount: NaN
has part: PIRSF000582
in compartment: metaid_0000003
name: PP2ACa_PKA
type: Species
constant: false
has part: IPR006186
boundary condition: false

209632
stoichiometry: 1.0
species: metaid_0000193
type: SpeciesReference

205944
value: 24.0
name: koff15
type: LocalParameter

metaid_0000164
in compartment: metaid_0000003
constant: false
type: Species
has part: CHEBI:17489
has part: PIRSF000548
initial concentration: 0.0
has part: PIRSF000582
initial amount: NaN
name: cAMP2_R2C2
boundary condition: false
has only substance units: false

metaid_0000206
kinetic law: 210210
product: 210198
product: 210186
reactant: 210174
fast: false
reversible: false
name: D75_PP2ACa_unbinding
type: Reaction

210381
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

203681
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

207608
stoichiometry: 1.0
species: metaid_0000137
type: SpeciesReference

208510
value: 7.5E7
name: kon39
type: LocalParameter

metaid_0000226
kinetic law: 211114
product: 211102
reactant: 211090
reactant: 211078
fast: false
reversible: false
name: PP2ACa_PKA_binding
type: Reaction

203911
stoichiometry: 1.0
species: metaid_0000047
type: SpeciesReference

207053
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

metaid_0000245
event assignment: 211594
trigger: 211581
use values from trigger time: true
name: ca_on5
type: Event

210717
stoichiometry: 1.0
species: metaid_0000219
type: SpeciesReference

207113
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

210657
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

205066
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

209017
stoichiometry: 1.0
species: metaid_0000177
type: SpeciesReference

metaid_0000265
constant: true
value: 2.0
name: spike_interval
type: Parameter

202468
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

metaid_0000090
kinetic law: 205450
product: 205438
reactant: 205426
reactant: 205414
fast: false
reversible: false
name: D34:137_PP2B_binding
type: Reaction

205354
stoichiometry: 1.0
species: metaid_0000087
type: SpeciesReference

204475
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000025
type: Species
in compartment: metaid_0000003
initial amount: NaN
has only substance units: false
initial concentration: 0.0
has part: Q03114
has part: Q9UD71
name: D34_CDK5
constant: false
boundary condition: false

209764
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

207668
stoichiometry: 1.0
species: metaid_0000143
type: SpeciesReference

210369
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

metaid_0000205
kinetic law: 210150
product: 210137
product: 210125
reactant: 210113
fast: false
reversible: false
name: D75_dephospho_by_PP2ACa_on_75
type: Reaction

metaid_0000165
initial concentration: 0.0
boundary condition: false
has part: PIRSF000548
in compartment: metaid_0000003
has part: PIRSF000582
initial amount: NaN
has only substance units: false
has part: CHEBI:17489
name: cAMP3_R2C2
constant: false
type: Species

metaid_0000225
kinetic law: 211054
product: 211042
product: 211030
reactant: 211018
fast: false
reversible: false
name: PP2A_Ca_unbinding
type: Reaction

203971
stoichiometry: 1.0
species: metaid_0000047
type: SpeciesReference

206016
stoichiometry: 1.0
species: metaid_0000103
type: SpeciesReference

206379
stoichiometry: 1.0
species: metaid_0000111
type: SpeciesReference

207716
stoichiometry: 1.0
species: metaid_0000145
type: SpeciesReference

metaid_0000246
event assignment: 211618
trigger: 211606
use values from trigger time: true
name: ca_on6
type: Event

203597
value: 3800000.0
name: kon9
type: LocalParameter

metaid_0000266
constant: true
value: 2.5E-8
name: kon_low
type: Parameter

206511
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

202600
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

202408
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

205018
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

204981
value: 3.0
name: kcat14
type: LocalParameter

metaid_0000026
kinetic law: 202913
product: 202901
reactant: 202889
reactant: 202877
fast: false
reversible: false
name: D34_CDK5_binding
type: Reaction

209295
value: 5040000.0
name: kon45
type: LocalParameter

metaid_0000264
constant: true
value: 2.0
name: spike_duration
type: Parameter

metaid_0000125
kinetic law: 207017
product: 207005
product: 206993
reactant: 206981
fast: false
reversible: false
name: D34:137_PP2C_unbinding
type: Reaction

metaid_0000020
initial amount: NaN
boundary condition: false
name: D_PKA
has part: PIRSF000582
constant: false
initial concentration: 0.0
has part: Q9UD71
has only substance units: false
in compartment: metaid_0000003
type: Species

204391
stoichiometry: 1.0
species: metaid_0000061
type: SpeciesReference

210053
stoichiometry: 1.0
species: metaid_0000202
type: SpeciesReference

metaid_0000040
kinetic law: 203465
product: 203453
reactant: 203441
reactant: 203429
fast: false
reversible: false
name: D75_CK1_binding
type: Reaction

203489
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

209572
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

203995
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

202987
value: 4400000.0
name: kon5
type: LocalParameter

metaid_0000080
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: D34:75:137
type: Species

204524
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

metaid_0000263
constant: true
value: 6.6E-6
name: kon_high
type: Parameter

206259
stoichiometry: 1.0
species: metaid_0000107
type: SpeciesReference

metaid_0000124
kinetic law: 206957
product: 206945
product: 206933
reactant: 206921
fast: false
reversible: false
name: D34:137_dephospho_by_PP2C_on_137
type: Reaction

203417
value: 16.0
name: koff6
type: LocalParameter

210137
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

204885
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

metaid_0000060
kinetic law: 204187
product: 204175
reactant: 204163
reactant: 204151
fast: false
reversible: false
name: D137_CDK5_binding
type: Reaction

208450
value: 5.4E7
name: kon38
type: LocalParameter

203815
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

206271
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

205848
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

203729
stoichiometry: 1.0
species: metaid_0000041
type: SpeciesReference

metaid_0000262
constant: true
value: 50.0
name: cAMP_Ca_delay
type: Parameter

metaid_0000149
has only substance units: false
has part: PIRSF000582
in compartment: metaid_0000003
has part: IPR006186
boundary condition: false
type: Species
name: PP2A_PKA
initial amount: NaN
initial concentration: 0.0
constant: false

metaid_0000022
kinetic law: 202792
product: 202780
product: 202768
reactant: 202756
fast: false
reversible: false
name: D_PKA_unbinding
type: Reaction

207789
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000081
kinetic law: 205029
product: 205018
product: 205005
reactant: 204993
fast: false
reversible: false
name: D34:137_phospho_by_CDK5_on_75
type: Reaction

209932
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

208716
stoichiometry: 1.0
species: metaid_0000164
type: SpeciesReference

207873
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

211102
stoichiometry: 1.0
species: metaid_0000227
type: SpeciesReference

metaid_0000127
is version of: IPR000396
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.0E-6
initial amount: NaN
in compartment: metaid_0000003
name: PDE
type: Species

202925
value: 5600000.0
name: kon4
type: LocalParameter

208402
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

204584
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000042
kinetic law: 203525
product: 203513
reactant: 203501
reactant: 203489
fast: false
reversible: false
name: D75_PKA_binding
type: Reaction

205775
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

205126
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

metaid_0000169
kinetic law: 208620
product: 208608
product: 208596
reactant: 208584
fast: false
reversible: false
name: cAMP_R2C2_unbinding
type: Reaction

metaid_0000061
initial concentration: 0.0
has only substance units: false
has part: Q9UD71
has part: Q03114
initial amount: NaN
in compartment: metaid_0000003
boundary condition: false
type: Species
constant: false
name: D137_CDK5

203189
stoichiometry: 1.0
species: metaid_0000028
type: SpeciesReference

211392
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

210429
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

metaid_0000148
kinetic law: 207909
product: 207897
reactant: 207885
reactant: 207873
fast: false
reversible: false
name: PP2A_PKA_binding
type: Reaction

metaid_0000261
constant: true
value: 400.0
name: cAMP_delay
type: Parameter

208005
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000082
kinetic law: 205090
product: 205078
reactant: 205066
reactant: 205054
fast: false
reversible: false
name: D75:137_PKA_binding
type: Reaction

metaid_0000021
kinetic law: 202732
product: 202720
reactant: 202708
reactant: 202696
fast: false
reversible: false
name: D_PKA_binding
type: Reaction

metaid_0000126
type: Species
has part: IPR015655
constant: false
has only substance units: false
has part: Q9UD71
name: D75:137_PP2C
initial amount: NaN
boundary condition: false
initial concentration: 0.0
in compartment: metaid_0000003

203501
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

203273
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000041
initial amount: NaN
boundary condition: false
name: D75_CK1
has only substance units: false
initial concentration: 0.0
in compartment: metaid_0000003
type: Species
has part: Q9UD71
has part: Q99PS2
constant: false

204945
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

203129
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

metaid_0000168
kinetic law: 208558
product: 208546
reactant: 208534
reactant: 208522
fast: false
reversible: false
name: cAMP3_R2C2_binding_by_cAMP
type: Reaction

metaid_0000062
kinetic law: 204247
product: 204235
reactant: 204223
reactant: 204211
fast: false
reversible: false
name: D137_PKA_binding
type: Reaction

204199
value: 5600000.0
name: kon11
type: LocalParameter

metaid_0000121
kinetic law: 206836
product: 206824
product: 206812
reactant: 206800
fast: false
reversible: false
name: D34:75:137_PP2AP_unbinding
type: Reaction

208041
value: 4.0
name: kcat33
type: LocalParameter

210477
stoichiometry: 1.0
species: metaid_0000208
type: SpeciesReference

209824
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

203064
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

205739
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

202348
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

205234
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

209596
stoichiometry: 1.0
species: metaid_0000193
type: SpeciesReference

metaid_0000147
kinetic law: 207849
product: 207837
reactant: 207825
fast: false
reversible: false
name: PDEP_dephospho
type: Reaction

metaid_0000083
constant: false
initial amount: NaN
type: Species
has part: PIRSF000582
in compartment: metaid_0000003
has part: Q9UD71
has only substance units: false
initial concentration: 0.0
name: D75:137_PKA
boundary condition: false

metaid_0000260
event assignment: 211933
trigger: 211921
use values from trigger time: true
name: ca_off10
type: Event

210321
stoichiometry: 1.0
species: metaid_0000211
type: SpeciesReference

metaid_0000044
kinetic law: 203585
product: 203573
reactant: 203561
reactant: 203549
fast: false
reversible: false
name: D75_PP2A_binding
type: Reaction

207283
stoichiometry: 1.0
species: metaid_0000133
type: SpeciesReference

208824
stoichiometry: 1.0
species: metaid_0000174
type: SpeciesReference

metaid_0000240
event assignment: 211441
trigger: 211429
use values from trigger time: true
name: cAMP_pulse
type: Event

204223
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000101
kinetic law: 205932
product: 205920
product: 205908
reactant: 205896
fast: false
reversible: false
name: D34:75_PP2A_unbinding
type: Reaction

BIOMD0000000153
reaction: metaid_0000090
reaction: metaid_0000201
reaction: metaid_0000057
species: metaid_0000174
parameter: metaid_0000266
reaction: metaid_0000073
reaction: metaid_0000199
reaction: metaid_0000158
species: metaid_0000091
reaction: metaid_0000099
species: metaid_0000164
reaction: metaid_0000122
reaction: metaid_0000136
reaction: metaid_0000153
event: metaid_0000250
species: metaid_0000019
event: metaid_0000245
reaction: metaid_0000190
reaction: metaid_0000017
reaction: metaid_0000058
species: metaid_0000066
reaction: metaid_0000033
reaction: metaid_0000159
reaction: metaid_0000229
reaction: metaid_0000059
event: metaid_0000241
reaction: metaid_0000189
reaction: metaid_0000175
species: metaid_0000137
species: metaid_0000098
reaction: metaid_0000075
reaction: metaid_0000212
reaction: metaid_0000112
reaction: metaid_0000150
event: metaid_0000256
event: metaid_0000251
reaction: metaid_0000109
species: metaid_0000177
reaction: metaid_0000213
species: metaid_0000211
species: metaid_0000162
is version of: GO:0007212
species: metaid_0000133
species: metaid_0000217
reaction: metaid_0000205
reaction: metaid_0000035
reaction: metaid_0000113
reaction: metaid_0000151
reaction: metaid_0000092
reaction: metaid_0000051
event: metaid_0000257
event: metaid_0000249
reaction: metaid_0000214
reaction: metaid_0000181
species: metaid_0000119
is version of: GO:0035235
species: metaid_0000080
reaction: metaid_0000230
reaction: metaid_0000086
parameter: metaid_0000262
reaction: metaid_0000036
reaction: metaid_0000135
event: metaid_0000253
reaction: metaid_0000187
reaction: metaid_0000224
species: metaid_0000034
species: metaid_0000209
reaction: metaid_0000011
reaction: metaid_0000052
reaction: metaid_0000110
species: metaid_0000149
reaction: metaid_0000182
reaction: metaid_0000141
species: metaid_0000191
species: metaid_0000165
species: metaid_0000004
species: metaid_0000014
species: metaid_0000087
parameter: metaid_0000263
event: metaid_0000248

209536
stoichiometry: 1.0
species: metaid_0000192
type: SpeciesReference

205438
stoichiometry: 1.0
species: metaid_0000091
type: SpeciesReference

metaid_0000120
kinetic law: 206776
product: 206763
reactant: 206751
reactant: 206739
fast: false
reversible: false
name: D34:75:137_PP2AP_binding
type: Reaction

210113
stoichiometry: 1.0
species: metaid_0000200
type: SpeciesReference

205824
value: 3800000.0
name: kon15
type: LocalParameter

208474
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

203839
value: 0.0
name: kcat8
type: LocalParameter

metaid_0000084
kinetic law: 205150
product: 205138
product: 205126
reactant: 205114
fast: false
reversible: false
name: D75:137_phospho_by_PKA_on_34
type: Reaction

metaid_0000146
kinetic law: 207801
product: 207789
product: 207777
reactant: 207765
fast: false
reversible: false
name: PDE_PKA_unbinding
type: Reaction

metaid_0000043
type: Species
in compartment: metaid_0000003
constant: false
has part: Q9UD71
name: D75_PKA
initial amount: NaN
initial concentration: 0.0
boundary condition: false
has part: PIRSF000582
has only substance units: false

204283
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

207933
stoichiometry: 1.0
species: metaid_0000149
type: SpeciesReference

209247
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

metaid_0000100
kinetic law: 205872
product: 205860
product: 205848
reactant: 205836
fast: false
reversible: false
name: D34:75_dephospho_by_PP2A_on_75
type: Reaction

204500
value: 10.8
name: koff12
type: LocalParameter

206812
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

211078
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

210537
stoichiometry: 1.0
species: metaid_0000208
type: SpeciesReference

metaid_0000123
boundary condition: false
name: D34:137_PP2C
has only substance units: false
in compartment: metaid_0000003
has part: Q9UD71
has part: IPR015655
initial amount: NaN
type: Species
constant: false
initial concentration: 0.0

metaid_0000085
kinetic law: 205210
product: 205198
product: 205186
reactant: 205174
fast: false
reversible: false
name: D75:137_PKA_unbinding
type: Reaction

206547
value: 1.7E7
name: kon23
type: LocalParameter

metaid_0000145
is version of: IPR000396
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: PDEP
type: Species

209981
value: 3800000.0
name: kon49
type: LocalParameter

211090
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000103
name: D75:137_PP2A
type: Species
has only substance units: false
initial concentration: 0.0
in compartment: metaid_0000003
boundary condition: false
constant: false
initial amount: NaN
has part: Q9UD71
has part: IPR006186

207897
stoichiometry: 1.0
species: metaid_0000149
type: SpeciesReference

metaid_0000122
kinetic law: 206897
product: 206885
reactant: 206873
reactant: 206861
fast: false
reversible: false
name: D34:137_PP2C_binding
type: Reaction

metaid_0000086
kinetic law: 205270
product: 205258
reactant: 205246
reactant: 205234
fast: false
reversible: false
name: D34:75_PP2B_binding
type: Reaction

metaid_0000144
kinetic law: 207740
product: 207728
product: 207716
reactant: 207704
fast: false
reversible: false
name: PDE_phospho_by_PKA
type: Reaction

208896
stoichiometry: 1.0
species: metaid_0000174
type: SpeciesReference

206149
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

206331
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000045
is version of: IPR006186
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.0E-7
initial amount: NaN
in compartment: metaid_0000003
name: PP2A
type: Species

metaid_0000102
kinetic law: 205992
product: 205980
reactant: 205968
reactant: 205956
fast: false
reversible: false
name: D75:137_PP2A_binding
type: Reaction

204019
value: 24.0
name: koff9
type: LocalParameter

metaid_0000067
kinetic law: 204367
product: 204355
product: 204343
reactant: 204331
fast: false
reversible: false
name: D137_CDK5_unbinding
type: Reaction

203141
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

209680
value: 10.0
name: kcat47
type: LocalParameter

metaid_0000105
kinetic law: 206113
product: 206101
product: 206089
reactant: 206077
fast: false
reversible: false
name: D75:137_PP2A_unbinding
type: Reaction

209427
stoichiometry: 1.0
species: metaid_0000232
type: SpeciesReference

207497
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

207957
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

207457
value: 3.0E7
name: kon29
type: LocalParameter

205498
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

207392
value: 12.0
name: koff28
type: LocalParameter

209355
value: 80.0
name: koff45
type: LocalParameter

207149
value: 3.0
name: kcat24
type: LocalParameter

208788
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

204813
stoichiometry: 1.0
species: metaid_0000076
type: SpeciesReference

208584
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

210186
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

210005
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

204753
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

metaid_0000087
initial concentration: 0.0
initial amount: NaN
boundary condition: false
name: D34:75_PP2B
has only substance units: false
in compartment: metaid_0000003
has part: PIRSF000911
has part: Q9UD71
type: Species
constant: false
has part: CHEBI:29108

210849
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

210861
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

metaid_0000068
kinetic law: 204427
product: 204415
product: 204403
reactant: 204391
fast: false
reversible: false
name: D137_Phospho_by_CDK5_on_75
type: Reaction

207343
stoichiometry: 1.0
species: metaid_0000133
type: SpeciesReference

204115
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

206703
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

208848
stoichiometry: 1.0
species: metaid_0000166
type: SpeciesReference

metaid_0000104
kinetic law: 206053
product: 206041
product: 206029
reactant: 206016
fast: false
reversible: false
name: D75:137_dephospho_by_PP2A_on_75
type: Reaction

202516
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

211127
value: 1.0E7
name: kon55
type: LocalParameter

205414
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

203357
value: 4.0
name: kcat6
type: LocalParameter

205198
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

205715
stoichiometry: 1.0
species: metaid_0000094
type: SpeciesReference

206487
value: 40.0
name: koff16
type: LocalParameter

208065
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000088
kinetic law: 205330
product: 205318
product: 205306
reactant: 205294
fast: false
reversible: false
name: D34:75_PP2B_unbinding
type: Reaction

205258
stoichiometry: 1.0
species: metaid_0000087
type: SpeciesReference

203441
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

203549
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

206125
value: 24.0
name: koff22
type: LocalParameter

metaid_0000069
kinetic law: 204487
product: 204475
product: 204463
reactant: 204451
fast: false
reversible: false
name: D137_PKA_unbinding
type: Reaction

211703
persistant: true
initial value: true
type: Trigger

204151
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

207405
stoichiometry: 1.0
species: metaid_0000137
type: SpeciesReference

metaid_0000089
kinetic law: 205390
product: 205378
product: 205366
reactant: 205354
fast: false
reversible: false
name: D34:75_dephopsho_by_PP2B_on_34
type: Reaction

206607
value: 24.0
name: kcat23
type: LocalParameter

206763
stoichiometry: 1.0
species: metaid_0000119
type: SpeciesReference

metaid_0000107
initial concentration: 0.0
in compartment: metaid_0000003
initial amount: NaN
constant: false
has part: Q9UD71
has only substance units: false
name: D34:75:137_PP2A
boundary condition: false
type: Species
has part: IPR006186

203609
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

210284
value: 1.7E7
name: kon50
type: LocalParameter

211260
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

205306
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

209716
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

211188
value: 4.0
name: kcat55
type: LocalParameter

metaid_0000106
kinetic law: 206174
product: 206162
reactant: 206149
reactant: 206137
fast: false
reversible: false
name: D34:75:137_PP2A_binding
type: Reaction

207125
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

206873
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

208764
stoichiometry: 1.0
species: metaid_0000166
type: SpeciesReference

metaid_0000063
constant: false
has only substance units: false
initial concentration: 0.0
in compartment: metaid_0000003
boundary condition: false
name: D137_PKA
initial amount: NaN
type: Species
has part: Q9UD71
has part: PIRSF000582

209463
stoichiometry: 1.0
species: metaid_0000154
type: SpeciesReference

204837
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

210162
value: 10.0
name: kcat48
type: LocalParameter

204777
stoichiometry: 1.0
species: metaid_0000076
type: SpeciesReference

metaid_0000129
kinetic law: 207077
product: 207065
reactant: 207053
reactant: 207041
fast: false
reversible: false
name: D75:137_PP2C_binding
type: Reaction

metaid_0000109
kinetic law: 206295
product: 206283
product: 206271
reactant: 206259
fast: false
reversible: false
name: D34:75:137_PP2A_unbinding
type: Reaction

211429
persistant: true
initial value: true
type: Trigger

211018
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

210825
value: 10.0
name: koff53
type: LocalParameter

210897
stoichiometry: 1.0
species: metaid_0000217
type: SpeciesReference

206463
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

209379
stoichiometry: 1.0
species: metaid_0000183
type: SpeciesReference

211320
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

208089
value: 5.0
name: kcat34
type: LocalParameter

205594
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

203333
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

202877
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

206162
stoichiometry: 1.0
species: metaid_0000107
type: SpeciesReference

210077
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

205174
stoichiometry: 1.0
species: metaid_0000083
type: SpeciesReference

metaid_0000064
kinetic law: 204307
product: 204295
reactant: 204283
reactant: 204271
fast: false
reversible: false
name: D137_PP2C_binding
type: Reaction

metaid_0000128
is version of: PIRSF000911
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3.32E-7
initial amount: NaN
in compartment: metaid_0000003
name: PP2Binactive
type: Species

206101
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

206788
value: 1.7E7
name: kon26
type: LocalParameter

208173
stoichiometry: 2.0
species: metaid_0000154
type: SpeciesReference

202817
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000108
kinetic law: 206235
product: 206223
product: 206210
reactant: 206198
fast: false
reversible: false
name: D34:75:137_dephospho_by_PP2A_on_75
type: Reaction

210885
value: 24.0
name: kcat52
type: LocalParameter

204175
stoichiometry: 1.0
species: metaid_0000061
type: SpeciesReference

207367
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

metaid_0000065
boundary condition: false
type: Species
has part: IPR015655
initial concentration: 0.0
initial amount: NaN
has part: Q9UD71
constant: false
has only substance units: false
in compartment: metaid_0000003
name: D137_PP2C

210681
stoichiometry: 1.0
species: metaid_0000219
type: SpeciesReference

211284
stoichiometry: 1.0
species: metaid_0000154
type: SpeciesReference

202708
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

206679
stoichiometry: 1.0
species: metaid_0000119
type: SpeciesReference

203297
value: 3.0
name: kcat5
type: LocalParameter

207431
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

208426
stoichiometry: 1.0
species: metaid_0000164
type: SpeciesReference

208113
stoichiometry: 2.0
species: metaid_0000154
type: SpeciesReference

205102
value: 5600000.0
name: kon21
type: LocalParameter

211728
persistant: true
initial value: true
type: Trigger

metaid_0000066
is version of: IPR015655
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.33E-7
initial amount: NaN
in compartment: metaid_0000003
name: PP2C
type: Species

210405
value: 24.0
name: kcat51
type: LocalParameter

207765
stoichiometry: 1.0
species: metaid_0000143
type: SpeciesReference

207470
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

211212
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species: metaid_0000154
type: SpeciesReference

202901
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

203863
stoichiometry: 1.0
species: metaid_0000007
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206739
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

202720
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

206631
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

208752
value: 110.0
name: koff39
type: LocalParameter

202636
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

208656
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

206004
value: 3800000.0
name: kon22
type: LocalParameter

metaid_0000210
kinetic law: 210333
product: 210321
reactant: 210308
reactant: 210296
fast: false
reversible: false
name: D34:75:137_PP2APCa_binding
type: Reaction

205474
stoichiometry: 1.0
species: metaid_0000091
type: SpeciesReference

207210
value: 12.0
name: koff24
type: LocalParameter

209137
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

202588
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

204620
value: 3.0
name: kcat13
type: LocalParameter

210777
stoichiometry: 1.0
species: metaid_0000219
type: SpeciesReference

205078
stoichiometry: 1.0
species: metaid_0000083
type: SpeciesReference

211849
persistant: true
initial value: true
type: Trigger

209884
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

203669
stoichiometry: 1.0
species: metaid_0000041
type: SpeciesReference

210729
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

207523
value: 24.0
name: koff29
type: LocalParameter

209475
stoichiometry: 1.0
species: metaid_0000232
type: SpeciesReference

207173
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

207837
stoichiometry: 1.0
species: metaid_0000127
type: SpeciesReference

203851
stoichiometry: 1.0
species: metaid_0000043
type: SpeciesReference

206077
stoichiometry: 1.0
species: metaid_0000103
type: SpeciesReference

208692
value: 33.0
name: koff38
type: LocalParameter

204861
value: 12.0
name: koff18
type: LocalParameter

207548
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

204139
value: 40.0
name: koff10
type: LocalParameter

metaid_0000212
kinetic law: 210393
product: 210381
product: 210369
reactant: 210357
fast: false
reversible: false
name: D34:75:137_dephospho_by_PP2APCa_on_75
type: Reaction

210981
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

209187
stoichiometry: 1.0
species: metaid_0000180
type: SpeciesReference

205534
stoichiometry: 1.0
species: metaid_0000091
type: SpeciesReference

206319
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

210222
value: 6.0
name: koff48
type: LocalParameter

206403
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

210969
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

203201
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

211368
stoichiometry: 1.0
species: metaid_0000227
type: SpeciesReference

metaid_0000211
initial concentration: 0.0
has only substance units: false
has part: IPR006186
type: Species
constant: false
boundary condition: false
in compartment: metaid_0000003
initial amount: NaN
has part: Q9UD71
name: D34:75:137_PP2APCa
has part: CHEBI:29108

206499
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

207632
value: 1.0
name: kcat30
type: LocalParameter

207234
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

208546
stoichiometry: 1.0
species: metaid_0000166
type: SpeciesReference

metaid_0000197
kinetic law: 209788
product: 209776
product: 209764
reactant: 209752
fast: false
reversible: false
name: D34:75_dephospho_by_PP2ACa_on_75
type: Reaction

208632
value: 33.0
name: koff37
type: LocalParameter

203561
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

202744
value: 5600000.0
name: kon3
type: LocalParameter

209053
value: 60.0
name: kon43
type: LocalParameter

metaid_0000099
kinetic law: 205812
product: 205800
reactant: 205787
reactant: 205775
fast: false
reversible: false
name: D34:75_PP2A_binding
type: Reaction

209499
value: 1.7
name: k58
type: LocalParameter

207596
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

204031
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

204644
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

208222
stoichiometry: 1.0
species: metaid_0000155
type: SpeciesReference

206993
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

208149
value: 1.0E15
name: kon35
type: LocalParameter

204331
stoichiometry: 1.0
species: metaid_0000061
type: SpeciesReference

206691
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

204704
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000196
kinetic law: 209728
product: 209716
product: 209704
reactant: 209692
fast: false
reversible: false
name: D34:75:137_PP2ACa_unbinding
type: Reaction

204403
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

metaid_0000199
kinetic law: 209908
product: 209896
reactant: 209884
reactant: 209872
fast: false
reversible: false
name: D75_PP2ACa_binding
type: Reaction

metaid_0000170
kinetic law: 208680
product: 208668
product: 208656
reactant: 208644
fast: false
reversible: false
name: cAMP2_R2C2_unbinding
type: Reaction

205800
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

metaid_0000019
is version of: PIRSF000582
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: PKA
type: Species

205896
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

210945
value: 10.0
name: koff52
type: LocalParameter

211151
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

206583
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000059
kinetic law: 204127
product: 204115
product: 204103
reactant: 204091
fast: false
reversible: false
name: D75_PP2AP_unbinding
type: Reaction

metaid_0000171
kinetic law: 208740
product: 208728
product: 208716
reactant: 208704
fast: false
reversible: false
name: cAMP3_R2C2_unbinding
type: Reaction

206427
value: 24.0
name: kcat16
type: LocalParameter

206041
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000198
kinetic law: 209848
product: 209836
product: 209824
reactant: 209812
fast: false
reversible: false
name: D34:75_PP2ACa_unbinding
type: Reaction

203753
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

209511
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

204680
value: 12.0
name: koff13
type: LocalParameter

208246
stoichiometry: 2.0
species: metaid_0000154
type: SpeciesReference

202540
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

204055
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000193
in compartment: metaid_0000003
has part: CHEBI:29108
has part: IPR006186
name: D34:75:137_PP2ACa
has only substance units: false
boundary condition: false
initial concentration: 0.0
has part: Q9UD71
constant: false
initial amount: NaN
type: Species

metaid_0000037
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: D34:137
type: Species

206223
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

207993
stoichiometry: 1.0
species: metaid_0000149
type: SpeciesReference

209644
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

209752
stoichiometry: 1.0
species: metaid_0000192
type: SpeciesReference

204355
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000172
kinetic law: 208800
product: 208788
product: 208776
reactant: 208764
fast: false
reversible: false
name: cAMP4_R2C2_unbinding
type: Reaction

202456
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

211555
persistant: true
initial value: true
type: Trigger

210645
value: 1.7E7
name: kon52
type: LocalParameter

207041
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

209077
stoichiometry: 1.0
species: metaid_0000127
type: SpeciesReference

metaid_0000257
event assignment: 211861
trigger: 211849
use values from trigger time: true
name: ca_off7
type: Event

metaid_0000152
kinetic law: 208077
product: 208065
reactant: 208053
fast: false
reversible: false
name: PP2AP_dephospho
type: Reaction

metaid_0000096
kinetic law: 205691
product: 205679
product: 205667
reactant: 205655
fast: false
reversible: false
name: D34:75:137_PP2B_unbinding
type: Reaction

metaid_0000218
kinetic law: 210693
product: 210681
reactant: 210669
reactant: 210657
fast: false
reversible: false
name: D75:137_PP2APCa_binding
type: Reaction

203621
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000017
kinetic law: 202612
product: 202600
product: 202588
reactant: 202576
fast: false
reversible: false
name: D_CDK1_unbinding
type: Reaction

211654
persistant: true
initial value: true
type: Trigger

metaid_0000130
kinetic law: 207137
product: 207125
product: 207113
reactant: 207101
fast: false
reversible: false
name: D75:137_dephospho_by_PP2C_137
type: Reaction

metaid_0000192
boundary condition: false
has part: CHEBI:29108
constant: false
type: Species
has only substance units: false
name: D34:75_PP2ACa
in compartment: metaid_0000003
initial concentration: 0.0
initial amount: NaN
has part: Q9UD71
has part: IPR006186

208522
stoichiometry: 1.0
species: metaid_0000165
type: SpeciesReference

metaid_0000018
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: D137
type: Species

metaid_0000038
kinetic law: 203345
product: 203333
product: 203321
reactant: 203309
fast: false
reversible: false
name: D34_Dephospho_by_PP2B
type: Reaction

204993
stoichiometry: 1.0
species: metaid_0000076
type: SpeciesReference

metaid_0000230
kinetic law: 211296
product: 211284
product: 211272
reactant: 211260
fast: false
reversible: false
name: PP2APCa_unbinding
type: Reaction

208884
stoichiometry: 1.0
species: metaid_0000166
type: SpeciesReference

202768
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000173
kinetic law: 208860
product: 208848
reactant: 208836
reactant: 208824
fast: false
reversible: false
name: cAMP4_R2C_PKA_binding
type: Reaction

210441
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

metaid_0000131
kinetic law: 207198
product: 207185
product: 207173
reactant: 207161
fast: false
reversible: false
name: D75:137_PP2C_unbinding
type: Reaction

209005
stoichiometry: 1.0
species: metaid_0000174
type: SpeciesReference

metaid_0000258
event assignment: 211885
trigger: 211873
use values from trigger time: true
name: ca_off8
type: Event

metaid_0000095
kinetic law: 205630
product: 205618
reactant: 205606
reactant: 205594
fast: false
reversible: false
name: D34:75:137_PP2B_binding
type: Reaction

210909
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

metaid_0000217
in compartment: metaid_0000003
initial concentration: 0.0
constant: false
type: Species
has part: IPR006186
boundary condition: false
has part: CHEBI:29108
has only substance units: false
name: D75_PP2APCa
initial amount: NaN
has part: Q9UD71

209812
stoichiometry: 1.0
species: metaid_0000192
type: SpeciesReference

207704
stoichiometry: 1.0
species: metaid_0000143
type: SpeciesReference

metaid_0000153
kinetic law: 208137
product: 208125
reactant: 208113
reactant: 208101
fast: false
reversible: false
name: PP2Binactive_Ca_binding
type: Reaction

205342
value: 1600.0
name: koff17
type: LocalParameter

207656
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

210621
stoichiometry: 1.0
species: metaid_0000217
type: SpeciesReference

metaid_0000195
kinetic law: 209668
product: 209656
product: 209644
reactant: 209632
fast: false
reversible: false
name: D34:75:137_dephospho_by_PP2ACa_on_75
type: Reaction

metaid_0000035
kinetic law: 203225
product: 203213
product: 203201
reactant: 203189
fast: false
reversible: false
name: D34_CK1_unbinding
type: Reaction

metaid_0000174
type: Species
boundary condition: false
initial amount: NaN
has part: PIRSF000548
initial concentration: 0.0
in compartment: metaid_0000003
has only substance units: false
name: cAMP4_R2C
has part: PIRSF000582
has part: CHEBI:17489
constant: false

208330
value: 1.0
name: koff36
type: LocalParameter

202396
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

metaid_0000231
kinetic law: 211344
product: 211332
reactant: 211320
fast: false
reversible: false
name: PP2APCa_dephospho
type: Reaction

metaid_0000259
event assignment: 211909
trigger: 211897
use values from trigger time: true
name: ca_off9
type: Event

208945
stoichiometry: 1.0
species: metaid_0000177
type: SpeciesReference

205667
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

202696
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000015
constant: false
has part: Q9UD71
initial concentration: 0.0
has part: Q99PS2
type: Species
boundary condition: false
initial amount: NaN
in compartment: metaid_0000003
name: D_CK1
has only substance units: false

211503
persistant: true
initial value: true
type: Trigger

metaid_0000098
constant: false
boundary condition: false
has part: IPR006186
type: Species
in compartment: metaid_0000003
initial amount: NaN
has part: Q9UD71
name: D34:75_PP2A
initial concentration: 0.0
has only substance units: false

metaid_0000154
is: CHEBI:29108
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: Ca
type: Species

metaid_0000036
kinetic law: 203285
product: 203273
product: 203261
reactant: 203249
fast: false
reversible: false
name: D34_Phospho_by_CK1_on_137
type: Reaction

metaid_0000194
kinetic law: 209608
product: 209596
reactant: 209584
reactant: 209572
fast: false
reversible: false
name: D34:75:137_PP2ACa_binding
type: Reaction

209620
value: 3800000.0
name: kon47
type: LocalParameter

metaid_0000175
kinetic law: 208921
product: 208908
product: 208896
reactant: 208884
fast: false
reversible: false
name: cAMP4_R2C2_PKA_unbinding
type: Reaction

202963
stoichiometry: 1.0
species: metaid_0000028
type: SpeciesReference

metaid_0000232
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: Empty
type: Species

metaid_0000097
kinetic law: 205751
product: 205739
product: 205727
reactant: 205715
fast: false
reversible: false
name: D34:75:137_dephospho_by_PP2B_on_34
type: Reaction

211308
value: 1.0
name: koff56
type: LocalParameter

205606
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

203025
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

202480
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000016
kinetic law: 202672
product: 202660
product: 202648
reactant: 202636
fast: false
reversible: false
name: D_Phospho_by_CK1_on_137
type: Reaction

209271
stoichiometry: 1.0
species: metaid_0000185
type: SpeciesReference

metaid_0000155
name: PP2BinactiveCa2
initial amount: NaN
in compartment: metaid_0000003
has part: CHEBI:29108
boundary condition: false
type: Species
has only substance units: false
initial concentration: 0.0
has part: PIRSF000911
constant: false

metaid_0000219
type: Species
has part: Q9UD71
initial concentration: 0.0
in compartment: metaid_0000003
has part: IPR006186
boundary condition: false
initial amount: NaN
has part: CHEBI:29108
has only substance units: false
name: D75:137_PP2APCa
constant: false

203309
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

211630
persistant: true
initial value: true
type: Trigger

metaid_0000233
kinetic law: 211404
product: 211392
product: 211380
reactant: 211368
fast: false
reversible: false
name: PP2ACa_PKA_unbinding
type: Reaction

207813
value: 36.0
name: koff31
type: LocalParameter

207065
stoichiometry: 1.0
species: metaid_0000126
type: SpeciesReference

203923
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

210705
value: 1.7E7
name: kon53
type: LocalParameter

207101
stoichiometry: 1.0
species: metaid_0000126
type: SpeciesReference

metaid_0000176
kinetic law: 208981
product: 208969
reactant: 208957
reactant: 208945
fast: false
reversible: false
name: cAMP4_R2_PKA_binding
type: Reaction

207307
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

W3 CDTF: Thu Jul 05 17:47:35 BST 2012

metaid_0000214
kinetic law: 210513
product: 210501
product: 210489
reactant: 210477
fast: false
reversible: false
name: D34:75_dephospho_by_PP2APCa_on_75
type: Reaction

205366
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

204463
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000013
kinetic law: 202492
product: 202480
product: 202468
reactant: 202456
fast: false
reversible: false
name: DPhospho_by_CDK5_on_75
type: Reaction

205005
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

202564
value: 4400000.0
name: kon2
type: LocalParameter

209029
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000253
event assignment: 211764
trigger: 211752
use values from trigger time: true
name: ca_off3
type: Event

210669
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

metaid_0000092
kinetic law: 205510
product: 205498
product: 205486
reactant: 205474
fast: false
reversible: false
name: D34:137_dephospho_by_PP2B_on_34
type: Reaction

205054
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

206848
value: 40.0
name: koff26
type: LocalParameter

210308
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

209860
value: 6.0
name: koff46
type: LocalParameter

204379
value: 12.0
name: koff11
type: LocalParameter

205642
value: 75000.0
name: kon27
type: LocalParameter

207728
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

206367
value: 1.7E7
name: kon16
type: LocalParameter

203983
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

metaid_0000177
initial amount: NaN
in compartment: metaid_0000003
has part: CHEBI:17489
type: Species
constant: false
has only substance units: false
name: cAMP4_R2
initial concentration: 0.0
has part: PIRSF000548
boundary condition: false

210357
stoichiometry: 1.0
species: metaid_0000211
type: SpeciesReference

203778
value: 3.0
name: kcat7
type: LocalParameter

209776
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

209113
value: 2520000.0
name: kon44
type: LocalParameter

metaid_0000213
kinetic law: 210453
product: 210441
product: 210429
reactant: 210417
fast: false
reversible: false
name: D34:75:137_PP2APCa_unbinding
type: Reaction

204079
value: 24.0
name: kcat10
type: LocalParameter

203693
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000014
is version of: Q99PS2
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.66E-7
initial amount: NaN
in compartment: metaid_0000003
name: CK1
type: Species

metaid_0000254
event assignment: 211789
trigger: 211776
use values from trigger time: true
name: ca_off4
type: Event

206523
stoichiometry: 1.0
species: metaid_0000115
type: SpeciesReference

metaid_0000091
in compartment: metaid_0000003
has only substance units: false
initial amount: NaN
has part: CHEBI:29108
constant: false
has part: PIRSF000911
type: Species
initial concentration: 0.0
name: D34:137_PP2B
boundary condition: false
has part: Q9UD71

209307
stoichiometry: 1.0
species: metaid_0000185
type: SpeciesReference

206029
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

208969
stoichiometry: 1.0
species: metaid_0000174
type: SpeciesReference

metaid_0000039
kinetic law: 203405
product: 203393
product: 203381
reactant: 203369
fast: false
reversible: false
name: D34_PP2B_unbinding
type: Reaction

metaid_0000191
is version of: IPR006186
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: PP2ACa
type: Species

metaid_0000178
kinetic law: 209041
product: 209029
product: 209017
reactant: 209005
fast: false
reversible: false
name: cAMP4_R2C_PKA_unbinding
type: Reaction

208608
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

metaid_0000216
kinetic law: 210633
product: 210621
reactant: 210609
reactant: 210597
fast: false
reversible: false
name: D75_PP2APCa_binding
type: Reaction

208282
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

metaid_0000011
kinetic law: 202552
product: 202540
reactant: 202528
reactant: 202516
fast: false
reversible: false
name: DCDK1_binding
type: Reaction

metaid_0000150
kinetic law: 207969
product: 207957
product: 207945
reactant: 207933
fast: false
reversible: false
name: PP2A_PKA_unbinding
type: Reaction

metaid_0000094
has part: Q9UD71
initial amount: NaN
type: Species
has only substance units: false
boundary condition: false
name: D34:75:137_PP2B
has part: CHEBI:29108
in compartment: metaid_0000003
initial concentration: 0.0
constant: false
has part: PIRSF000911

208017
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

206186
value: 3800000.0
name: kon25
type: LocalParameter

210246
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

208354
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

metaid_0000255
event assignment: 211813
trigger: 211801
use values from trigger time: true
name: ca_off5
type: Event

205968
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000236
constant: false
value: 2.5E-8
name: ca_in
type: Parameter

203381
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

W3 CDTF: Tue Mar 28 16:55:39 BST 2006

metaid_0000215
kinetic law: 210573
product: 210561
product: 210549
reactant: 210537
fast: false
reversible: false
name: D34:75_PP2APCa_unbinding
type: Reaction

205763
value: 0.03
name: kcat27
type: LocalParameter

metaid_0000179
kinetic law: 209101
product: 209089
reactant: 209077
reactant: 209065
fast: false
reversible: false
name: cAMP_PDE_binding
type: Reaction

206933
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000190
kinetic law: 209548
product: 209536
reactant: 209523
reactant: 209511
fast: false
reversible: false
name: D34:75_PP2ACa_binding
type: Reaction

205558
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

metaid_0000012
kinetic law: 202432
product: 202420
product: 202408
reactant: 202396
fast: false
reversible: false
name: D_CDK5_unbinding
type: Reaction

metaid_0000151
kinetic law: 208029
product: 208017
product: 208005
reactant: 207993
fast: false
reversible: false
name: PP2A_phospho_by_PKA
type: Reaction

metaid_0000256
event assignment: 211837
trigger: 211825
use values from trigger time: true
name: ca_off6
type: Event

metaid_0000093
kinetic law: 205570
product: 205558
product: 205546
reactant: 205534
fast: false
reversible: false
name: D34:137_PP2B_unbinding
type: Reaction

209944
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

211873
persistant: true
initial value: true
type: Trigger

207777
stoichiometry: 1.0
species: metaid_0000127
type: SpeciesReference

209150
stoichiometry: 1.0
species: metaid_0000127
type: SpeciesReference

203717
value: 12.0
name: koff7
type: LocalParameter

metaid_0000250
event assignment: 211716
trigger: 211703
use values from trigger time: true
name: ca_on10
type: Event

208728
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

206559
stoichiometry: 1.0
species: metaid_0000115
type: SpeciesReference

203177
value: 3.0
name: kcat4
type: LocalParameter

210741
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

210417
stoichiometry: 1.0
species: metaid_0000211
type: SpeciesReference

metaid_0000030
boundary condition: false
has part: Q9UD71
constant: false
initial amount: NaN
type: Species
has part: PIRSF000911
has part: CHEBI:29108
in compartment: metaid_0000003
name: D34_PP2B
initial concentration: 0.0
has only substance units: false

210501
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

211042
stoichiometry: 1.0
species: metaid_0000154
type: SpeciesReference

205787
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

metaid_0000139
kinetic law: 207510
product: 207497
product: 207484
reactant: 207470
fast: false
reversible: false
name: CK1P_PP2B_unbinding
type: Reaction

205114
stoichiometry: 1.0
species: metaid_0000083
type: SpeciesReference

203116
value: 12.0
name: koff4
type: LocalParameter

metaid_0000111
constant: false
has only substance units: false
in compartment: metaid_0000003
has part: IPR006186
boundary condition: false
type: Species
initial amount: NaN
initial concentration: 0.0
has part: Q9UD71
name: D34:75_PP2AP

metaid_0000138
type: Species
in compartment: metaid_0000003
name: CK1P_PP2B
constant: false
has part: PIRSF000911
has only substance units: false
has part: Q99PS2
initial amount: NaN
initial concentration: 0.0
boundary condition: false

204572
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

203261
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

206343
stoichiometry: 1.0
species: metaid_0000111
type: SpeciesReference

metaid_0000070
kinetic law: 204548
product: 204536
product: 204524
reactant: 204512
fast: false
reversible: false
name: D137_phospho_by_PKA_on_34
type: Reaction

metaid_0000050
initial amount: NaN
has part: IPR006186
initial concentration: 0.0
type: Species
constant: false
name: D75_PP2AP
has only substance units: false
in compartment: metaid_0000003
boundary condition: false
has part: Q9UD71

204933
stoichiometry: 1.0
species: metaid_0000074
type: SpeciesReference

207029
value: 12.0
name: koff20
type: LocalParameter

209523
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

207981
value: 16.0
name: koff33
type: LocalParameter

207861
value: 0.1
name: kcat32
type: LocalParameter

metaid_0000110
kinetic law: 206355
product: 206343
reactant: 206331
reactant: 206319
fast: false
reversible: false
name: D34:75_PP2AP_binding
type: Reaction

metaid_0000252
event assignment: 211740
trigger: 211728
use values from trigger time: true
name: ca_off2
type: Event

metaid_0000137
is version of: Q99PS2
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: CK1P
type: Species

204259
value: 5600000.0
name: kon12
type: LocalParameter

208812
value: 32.5
name: koff40
type: LocalParameter

209560
value: 3800000.0
name: kon46
type: LocalParameter

210041
value: 10.0
name: kcat49
type: LocalParameter

203321
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

202889
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

210489
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

202938
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

204512
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

206824
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000136
kinetic law: 207444
product: 207431
reactant: 207418
reactant: 207405
fast: false
reversible: false
name: CK1P_PP2B_binding
type: Reaction

metaid_0000251
event assignment: 211516
trigger: 211503
use values from trigger time: true
name: ca_off
type: Event

209211
stoichiometry: 1.0
species: metaid_0000127
type: SpeciesReference

204295
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

207921
value: 1.0E7
name: kon33
type: LocalParameter

208462
stoichiometry: 1.0
species: metaid_0000164
type: SpeciesReference

206283
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

207089
value: 7500000.0
name: kon24
type: LocalParameter

208186
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

206885
stoichiometry: 1.0
species: metaid_0000123
type: SpeciesReference

204897
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000209
has part: CHEBI:29108
has part: IPR006186
in compartment: metaid_0000003
initial concentration: 0.0
has only substance units: false
constant: false
type: Species
name: PP2APCa
boundary condition: false
initial amount: NaN

metaid_0000073
kinetic law: 204729
product: 204716
reactant: 204704
reactant: 204692
fast: false
reversible: false
name: D34:75_CK1_binding
type: Reaction

metaid_0000157
kinetic law: 208258
product: 208246
product: 208234
reactant: 208222
fast: false
reversible: false
name: PP2BinactiveCa2_Ca_unbinding
type: Reaction

209993
stoichiometry: 1.0
species: metaid_0000202
type: SpeciesReference

204596
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

metaid_0000135
kinetic law: 207379
product: 207367
product: 207355
reactant: 207343
fast: false
reversible: false
name: D34:75:137_PP2C_unbinding
type: Reaction

205138
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

204319
value: 7500000.0
name: kon13
type: LocalParameter

210525
value: 24.0
name: kcat50
type: LocalParameter

211066
value: 1.0
name: koff54
type: LocalParameter

207885
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000115
has only substance units: false
in compartment: metaid_0000003
constant: false
initial amount: NaN
boundary condition: false
has part: IPR006186
has part: Q9UD71
type: Species
name: D75:137_PP2AP
initial concentration: 0.0

209920
value: 3800000.0
name: kon48
type: LocalParameter

211606
persistant: true
initial value: true
type: Trigger

metaid_0000034
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: D34:75
type: Species

metaid_0000074
initial concentration: 0.0
boundary condition: false
has part: Q9UD71
has only substance units: false
has part: Q99PS2
in compartment: metaid_0000003
constant: false
initial amount: NaN
name: D34:75_CK1
type: Species

204957
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000156
kinetic law: 208198
product: 208186
reactant: 208173
reactant: 208161
fast: false
reversible: false
name: PP2B_activation
type: Reaction

208993
value: 1.8E7
name: kon42
type: LocalParameter

207005
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

203051
value: 1.0E7
name: kon6
type: LocalParameter

metaid_0000114
kinetic law: 206535
product: 206523
reactant: 206511
reactant: 206499
fast: false
reversible: false
name: D75:137_PP2AP_binding
type: Reaction

209656
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

metaid_0000033
kinetic law: 203165
product: 203153
product: 203141
reactant: 203129
fast: false
reversible: false
name: D34_Phospho_by_CDK5_on_75
type: Reaction

205222
value: 10.8
name: koff21
type: LocalParameter

203477
value: 4400000.0
name: kon7
type: LocalParameter

210465
value: 10.0
name: koff51
type: LocalParameter

metaid_0000071
kinetic law: 204608
product: 204596
product: 204584
reactant: 204572
fast: false
reversible: false
name: D137_dephospho_by_PP2C
type: Reaction

205294
stoichiometry: 1.0
species: metaid_0000087
type: SpeciesReference

205980
stoichiometry: 1.0
species: metaid_0000103
type: SpeciesReference

209584
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

202999
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000159
kinetic law: 208378
product: 208366
reactant: 208354
reactant: 208342
fast: false
reversible: false
name: R2C2_cAMP_binding
type: Reaction

metaid_0000008
kinetic law: 202372
product: 202360
reactant: 202348
reactant: 202336
fast: false
reversible: false
name: D_CDK5_binding
type: Reaction

metaid_0000133
has part: IPR015655
type: Species
initial amount: NaN
initial concentration: 0.0
constant: false
boundary condition: false
has only substance units: false
has part: Q9UD71
name: D34:75:137_PP2C
in compartment: metaid_0000003

202336
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

209836
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

204235
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

211139
stoichiometry: 1.0
species: metaid_0000227
type: SpeciesReference

205426
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

metaid_0000113
kinetic law: 206475
product: 206463
product: 206451
reactant: 206439
fast: false
reversible: false
name: D34:75_PP2AP_unbinding
type: Reaction

203791
stoichiometry: 1.0
species: metaid_0000043
type: SpeciesReference

metaid_0000032
kinetic law: 203103
product: 203090
product: 203077
reactant: 203064
fast: false
reversible: false
name: D34_CDK5_unbinding
type: Reaction

207271
value: 7500000.0
name: kon28
type: LocalParameter

208836
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

207331
value: 3.0
name: kcat28
type: LocalParameter

205836
stoichiometry: 1.0
species: metaid_0000098
type: SpeciesReference

208486
stoichiometry: 1.0
species: metaid_0000165
type: SpeciesReference

metaid_0000158
kinetic law: 208318
product: 208306
product: 208294
reactant: 208282
fast: false
reversible: false
name: PP2B_inactivation
type: Reaction

210198
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

metaid_0000072
kinetic law: 204668
product: 204656
product: 204644
reactant: 204632
fast: false
reversible: false
name: D137_PP2C_unbinding
type: Reaction

metaid_0000007
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: D75
type: Species

metaid_0000132
kinetic law: 207259
product: 207247
reactant: 207234
reactant: 207222
fast: false
reversible: false
name: D34:75:137_PP2C_binding
type: Reaction

211529
persistant: true
initial value: true
type: Trigger

210125
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

211678
persistant: true
initial value: true
type: Trigger

metaid_0000112
kinetic law: 206415
product: 206403
product: 206391
reactant: 206379
fast: false
reversible: false
name: D34:75_dephospho_by_PP2AP_on_75
type: Reaction

metaid_0000031
kinetic law: 203038
product: 203025
reactant: 203012
reactant: 202999
fast: false
reversible: false
name: D34_PP2B_binding
type: Reaction

206800
stoichiometry: 1.0
species: metaid_0000119
type: SpeciesReference

206247
value: 10.0
name: kcat25
type: LocalParameter

203153
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

209692
stoichiometry: 1.0
species: metaid_0000193
type: SpeciesReference

209439
stoichiometry: 1.0
species: metaid_0000154
type: SpeciesReference

204271
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

207945
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

209235
value: 10.0
name: kcat44
type: LocalParameter

211272
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

206137
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

metaid_0000006
has only substance units: false
in compartment: metaid_0000003
has part: Q03114
has part: Q9UD71
type: Species
initial amount: NaN
name: D_CDK5
constant: false
initial concentration: 0.0
boundary condition: false

203537
value: 5600000.0
name: kon8
type: LocalParameter

metaid_0000057
kinetic law: 204007
product: 203995
product: 203983
reactant: 203971
fast: false
reversible: false
name: D75_PP2A_unbinding
type: Reaction

202804
value: 10.8
name: koff3
type: LocalParameter

210921
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

206619
stoichiometry: 1.0
species: metaid_0000115
type: SpeciesReference

metaid_0000119
type: Species
boundary condition: false
has part: IPR006186
initial amount: NaN
initial concentration: 0.0
constant: false
in compartment: metaid_0000003
name: D34:75:137_PP2AP
has part: Q9UD71
has only substance units: false

206751
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

metaid_0000077
kinetic law: 204849
product: 204837
product: 204825
reactant: 204813
fast: false
reversible: false
name: D34:137_CDK5_unbinding
type: Reaction

203249
stoichiometry: 1.0
species: metaid_0000028
type: SpeciesReference

202780
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

204741
value: 4400000.0
name: kon14
type: LocalParameter

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

metaid_0000005
is: Q03114
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.0E-7
initial amount: NaN
in compartment: metaid_0000003
name: CDK5
type: Species

metaid_0000058
kinetic law: 204067
product: 204055
product: 204043
reactant: 204031
fast: false
reversible: false
name: D75_dephospho_by_PP2AP
type: Reaction

210296
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

203899
value: 10.8
name: koff8
type: LocalParameter

207418
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

metaid_0000118
kinetic law: 206715
product: 206703
product: 206691
reactant: 206679
fast: false
reversible: false
name: D34:75:137_dephospho_by_PP2AP_on 75
type: Reaction

metaid_0000078
kinetic law: 204909
product: 204897
product: 204885
reactant: 204873
fast: false
reversible: false
name: D34:75_CK1_unbinding
type: Reaction

208125
stoichiometry: 1.0
species: metaid_0000155
type: SpeciesReference

210549
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

211332
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

metaid_0000055
kinetic law: 203887
product: 203875
product: 203863
reactant: 203851
fast: false
reversible: false
name: D75_PKA_unbinding
type: Reaction

208390
value: 5.4E7
name: kon37
type: LocalParameter

metaid_0000004
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 4.98E-6
initial amount: NaN
in compartment: metaid_0000003
name: D
type: Species

209415
value: 20.0
name: kcat45
type: LocalParameter

210174
stoichiometry: 1.0
species: metaid_0000200
type: SpeciesReference

204765
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000117
kinetic law: 206655
product: 206643
product: 206631
reactant: 206619
fast: false
reversible: false
name: D75:137_PP2AP_unbinding
type: Reaction

210017
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

210101
value: 6.0
name: koff49
type: LocalParameter

210837
stoichiometry: 1.0
species: metaid_0000217
type: SpeciesReference

metaid_0000075
kinetic law: 204789
product: 204777
reactant: 204765
reactant: 204753
fast: false
reversible: false
name: D34:137_CDK5_binding
type: Reaction

208596
stoichiometry: 1.0
species: metaid_0000160
type: SpeciesReference

204801
value: 5600000.0
name: kon18
type: LocalParameter

204211
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

210609
stoichiometry: 1.0
species: metaid_0000209
type: SpeciesReference

205402
value: 4.0
name: kcat17
type: LocalParameter

202528
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

207295
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

metaid_0000056
kinetic law: 203947
product: 203935
product: 203923
reactant: 203911
fast: false
reversible: false
name: D75_dephospho_by_PP2A
type: Reaction

207355
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

metaid_0000116
kinetic law: 206595
product: 206583
product: 206571
reactant: 206559
fast: false
reversible: false
name: D75:137_dephospho_by_PP2AP_on_75
type: Reaction

metaid_0000003
is version of: GO:0043197
constant: true
size: 1.0E-15
spatial dimensions: 3.0
name: Spine
type: Compartment

metaid_0000076
has only substance units: false
name: D34:137_CDK5
has part: Q9UD71
initial concentration: 0.0
constant: false
boundary condition: false
type: Species
has part: Q03114
in compartment: metaid_0000003
initial amount: NaN

209259
stoichiometry: 1.0
species: metaid_0000145
type: SpeciesReference

205246
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

202841
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

203453
stoichiometry: 1.0
species: metaid_0000041
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203369
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

208053
stoichiometry: 1.0
species: metaid_0000049
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205727
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

205186
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

metaid_0000300
kinetic law: 207319
product: 207307
product: 207295
reactant: 207283
fast: false
reversible: false
name: D34:75:137_dephospho_by_PP2C_on_137
type: Reaction

metaid_0000053
is version of: Q9UD71
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
name: D75:137
type: Species

204163
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

203513
stoichiometry: 1.0
species: metaid_0000043
type: SpeciesReference

207752
value: 9.0
name: kcat31
type: LocalParameter

209704
stoichiometry: 1.0
species: metaid_0000080
type: SpeciesReference

211380
stoichiometry: 1.0
species: metaid_0000191
type: SpeciesReference

metaid_0000054
kinetic law: 203827
product: 203815
product: 203803
reactant: 203791
fast: false
reversible: false
name: D75_Phospho_by_PKA_on_34
type: Reaction

206667
value: 40.0
name: koff23
type: LocalParameter

208414
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

205318
stoichiometry: 1.0
species: metaid_0000029
type: SpeciesReference

208101
stoichiometry: 1.0
species: metaid_0000128
type: SpeciesReference

208704
stoichiometry: 1.0
species: metaid_0000165
type: SpeciesReference

203875
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

211200
stoichiometry: 1.0
species: metaid_0000049
type: SpeciesReference

211897
persistant: true
initial value: true
type: Trigger

211921
persistant: true
initial value: true
type: Trigger

205908
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

203803
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

208776
stoichiometry: 1.0
species: metaid_0000165
type: SpeciesReference

206861
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

metaid_0000051
kinetic law: 203705
product: 203693
product: 203681
reactant: 203669
fast: false
reversible: false
name: D75_CK1_unbinding
type: Reaction

204825
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

205486
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

206451
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

204536
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

209367
stoichiometry: 1.0
species: metaid_0000185
type: SpeciesReference

metaid_0000079
kinetic law: 204969
product: 204957
product: 204945
reactant: 204933
fast: false
reversible: false
name: D34:75_phospho_by_CK1_on_137
type: Reaction

211006
value: 200000.0
name: kon54
type: LocalParameter

202829
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

208161
stoichiometry: 1.0
species: metaid_0000155
type: SpeciesReference

210065
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

205162
value: 0.0
name: kcat21
type: LocalParameter

205582
value: 0.12
name: koff19
type: LocalParameter

210597
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

205703
value: 120.0
name: koff27
type: LocalParameter

202865
value: 2.7
name: kcat3
type: LocalParameter

metaid_0000052
kinetic law: 203766
product: 203753
product: 203741
reactant: 203729
fast: false
reversible: false
name: D75_Phospho_by_CK1_on_137
type: Reaction

202504
value: 3.0
name: kcat1
type: LocalParameter

204091
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

211416
value: 16.0
name: koff55
type: LocalParameter

204103
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

207484
stoichiometry: 1.0
species: metaid_0000137
type: SpeciesReference

ORG:
  orgname: EMBL-EBI
n:
  given: Nicolas
  family: Le Novère