metaid_0000023
kinetic law: 274002
reactant: 273990
is version of: GO:0006469
fast: false
reversible: false
name: x1 deactivation
type: Reaction

metaid_0000008
constant: true
value: 2.0
type: Parameter

metaid_0000004
has version: IPR003527
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
type: Species

metaid_0000013
constant: true
value: 1.0
type: Parameter

metaid_0000018
kinetic law: 273942
modifier: 273930
product: 273918
is version of: GO:0045860
is version of: GO:0032147
fast: false
reversible: false
name: x1 activates x2
type: Reaction

metaid_0000009
constant: true
value: 1.0
type: Parameter

metaid_0000022
kinetic law: 273978
modifier: 273966
product: 273954
is version of: GO:0045860
is version of: GO:0032147
fast: false
reversible: false
name: x1 activates y2
type: Reaction

274014
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000005
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
type: Species

273918
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000012
constant: true
value: 1.0
type: Parameter

274062
persistant: true
initial value: true
type: Trigger

metaid_0000019
event assignment: 274074
trigger: 274062
notes: x0 signaling applied as square pulses of magnitude 1 and duration 1.
is version of: GO:0051716
use values from trigger time: true
type: Event

273846
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

BIOMD0000000125
species: metaid_0000021
reaction: metaid_0000025
reaction: metaid_0000018
reaction: metaid_0000022
substance units: metaid_0000099
time units: metaid_0000097
parameter: metaid_0000009
is: MODEL2451230486
parameter: metaid_0000011
name: Komarova2005_TheoreticalFramework_BasicArchitecture
species: metaid_0000006
compartment: metaid_0000003
reaction: metaid_0000016
species: metaid_0000005
length unit: length
species: metaid_0000020
parameter: metaid_0000012
type: SBMLModel
is version of: GO:0051716
reaction: metaid_0000023
is described by: http://identifiers.org/pubmed/16729058
creator:
  ORG:
    orgname: BNMC
  n:
    given: Enuo
    family: He
is version of: GO:0007166
event: metaid_0000019
area units: metaid_0000005
parameter: metaid_0000007
is version of: GO:0030159
curated: true
species: metaid_0000004
reaction: metaid_0000017
modified:
  W3 CDTF: Thu Jul 05 17:31:20 BST 2012
volume units: metaid_0000084
reaction: metaid_0000024
occurs in: http://identifiers.org/taxonomy/33154
has version: GO:0000165
parameter: metaid_0000013
parameter: metaid_0000008
created:
  W3 CDTF: Mon Jun 04 16:33:08 BST 2007
parameter: metaid_0000010
notes: This model according to the paper A Theoretical Framework for Specificity in Cell Signalling The model is "basic architecture" of Figure2A. Figure2B, Figure2C have been reproduced by MathSBML. The reproduced figures are slightly different from the original ones in the paper, the peak of [x2] is higher than 1 and is not decreasing dramatically when [x0]=0. And I think maybe the author shift the or scale the curves. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
has version: map04010

metaid_0000025
kinetic law: 274050
reactant: 274038
is version of: GO:0006469
fast: false
reversible: false
name: y2 deactivation
type: Reaction

273990
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000006
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
type: Species

274038
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

metaid_0000021
notes: x0(t) and y0(t) are the signal functions. The authors assume the network only receives one of the two signals at a time. Thus, if y0(t) is postive for some duration of time, then x0(t) is identically zero, and visa versa.
has version: IPR002072
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000003
type: Species

metaid_0000016
kinetic law: 273870
modifier: 273858
product: 273846
is version of: GO:0045860
is version of: GO:0032147
fast: false
reversible: false
name: x0 activates x1
type: Reaction

metaid_0000011
constant: true
value: 1.0
type: Parameter

273882
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000003
is version of: GO:0005623
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

metaid_0000024
kinetic law: 274026
reactant: 274014
is version of: GO:0006469
fast: false
reversible: false
name: x2 deactivation
type: Reaction

273954
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

metaid_0000007
constant: true
value: 2.0
type: Parameter

metaid_0000020
notes: x0(t) and y0(t) are the signal functions. The authors assume the network only receives one of the two signals at a time. Thus, if x0(t) is postive for some duration of time, then y0(t) is identically zero, and visa versa.
has version: IPR006210
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000003
type: Species

metaid_0000017
kinetic law: 273906
modifier: 273894
product: 273882
is version of: GO:0045860
is version of: GO:0032147
fast: false
reversible: false
name: y0 activates x1
type: Reaction

metaid_0000010
constant: true
value: 1.0
type: Parameter