metaid_0000048
constant: false
value: NaN
type: Parameter

metaid_0000034
constant: true
value: 5.0
type: Parameter

metaid_0000068
constant: false
value: NaN
type: Parameter

metaid_0000075
notes: Ca ionic currents

metaid_0000013
constant: true
value: 1400.0
name: k current conductance
type: Parameter

metaid_0000023
constant: true
value: 0.3
type: Parameter

metaid_0000089
constant: false
value: NaN
type: Parameter

metaid_0000040
notes: gkatp = 500 if t < than tstim 530 otherwise
constant: false
value: 500.0
type: Parameter

metaid_0000061
constant: false
value: NaN
name: calcium current
type: Parameter

metaid_0000035
constant: true
value: 0.0
type: Parameter

metaid_0000049
constant: false
value: NaN
type: Parameter

026669
exponent: 1.0
scale: -3
multipler: 1.0
kind: VOLT
type: SBMLUnit

metaid_0000094
kinetic law: 026730
product: 026718
is version of: GO:0051924
fast: false
reversible: false
name: ER Ca2+ concentration
type: Reaction

metaid_0000012
constant: true
value: 900.0
name: ca activated k conductance
type: Parameter

metaid_0000093
kinetic law: 026706
product: 026694
is version of: GO:0051924
fast: false
reversible: false
name: cytosolic free Ca2+ concentration
type: Reaction

metaid_0000003
is version of: GO:0005623
constant: true
size: 1.0
spatial dimensions: 3.0
name: GH3 cell
type: Compartment

metaid_0000022
constant: true
value: 0.2
type: Parameter

metaid_0000088
notes: Ca2+ efflux through the IP3R
is version of: GO:0005220
is version of: GO:0006816

metaid_0000069
notes: activation function

026681
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000018
constant: true
value: 5300.0
name: membrane capacitance
type: Parameter

metaid_0000036
constant: true
value: 0.1
type: Parameter

metaid_0000046
constant: false
value: NaN
type: Parameter

026742
persistant: true
initial value: true
type: Trigger

metaid_0000097
unit: 026655
name: millisecond
type: SBMLUnitsDef

metaid_0000025
constant: true
value: -20.0
type: Parameter

metaid_0000077
notes: activation function

metaid_0000011
constant: true
value: 1000.0
name: ca current conductance
type: Parameter

metaid_0000103
constant: false
value: 0.008
type: Parameter

026718
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

metaid_0000066
constant: false
value: NaN
type: Parameter

BIOMD0000000124
rule: metaid_0000108
parameter: metaid_0000064
parameter: metaid_0000024
units def: metaid_0000099
rule: metaid_0000084
parameter: metaid_0000068
rule: metaid_0000107
parameter: metaid_0000035
rule: metaid_0000057
parameter: metaid_0000036
rule: metaid_0000090
parameter: metaid_0000079
parameter: metaid_0000017
parameter: metaid_0000048
parameter: metaid_0000025
rule: metaid_0000051
parameter: metaid_0000100
parameter: metaid_0000014
parameter: metaid_0000029
length unit: length
parameter: metaid_0000026
rule: metaid_0000052
species: metaid_0000006
species: metaid_0000007
rule: metaid_0000075
rule: metaid_0000110
rule: metaid_0000088
parameter: metaid_0000033
is version of: GO:0019228
rule: metaid_0000076
parameter: metaid_0000030
parameter: metaid_0000045
parameter: metaid_0000085
parameter: metaid_0000104
rule: metaid_0000069
reaction: metaid_0000093
parameter: metaid_0000013
parameter: metaid_0000042
substance units: metaid_0000099
rule: metaid_0000055
is: MODEL2981976537
parameter: metaid_0000065
parameter: metaid_0000101
rule: metaid_0000056
parameter: metaid_0000062
parameter: metaid_0000022
parameter: metaid_0000037
event: metaid_0000096
parameter: metaid_0000066
time units: metaid_0000097
volume units: metaid_0000084
occurs in: http://identifiers.org/taxonomy/10114
parameter: metaid_0000049
parameter: metaid_0000038
rule: metaid_0000106
rule: metaid_0000087
parameter: metaid_0000015
rule: metaid_0000080
parameter: metaid_0000102
compartment: metaid_0000003
rule: metaid_0000105
parameter: metaid_0000027
parameter: metaid_0000018
area units: metaid_0000005
rule: metaid_0000071
parameter: metaid_0000020
parameter: metaid_0000031
name: Wu2006_K+Channel
is version of: GO:0015272
parameter: metaid_0000043
parameter: metaid_0000034
parameter: metaid_0000083
rule: metaid_0000054
parameter: metaid_0000089
units def: metaid_0000098
parameter: metaid_0000011
rule: metaid_0000073
is version of: GO:0016570
parameter: metaid_0000046
rule: metaid_0000109

metaid_0000087
notes: fraction of open channels
is version of: GO:0005262

metaid_0000047
constant: false
value: NaN
type: Parameter

026694
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

metaid_0000096
event assignment: 026754
trigger: 026742
notes: Increase of maximal conductance of K_ATP channels from 500 to 530 at time=30000 ms
use values from trigger time: true
type: Event

metaid_0000037
constant: true
value: 0.14
type: Parameter

metaid_0000019
constant: true
value: 16.0
type: Parameter

metaid_0000104
constant: false
value: 0.282
type: Parameter

metaid_0000076
notes: activation function

metaid_0000090
notes: net Ca2+ efflux from the ER
is version of: GO:0006816

metaid_0000067
constant: false
value: NaN
type: Parameter

metaid_0000086
constant: false
value: NaN
type: Parameter

metaid_0000024
constant: true
value: -16.0
type: Parameter

metaid_0000080
notes: Flux of Ca2+ through the membrane
is version of: GO:0006816

metaid_0000044
constant: false
value: NaN
type: Parameter

metaid_0000099
unit: 026681
name: micromole
type: SBMLUnitsDef

metaid_0000070
notes: delayed rectifier K+ current
is version of: GO:0005251

metaid_0000016
constant: true
value: -75.0
name: k reversal potential
type: Parameter

metaid_0000026
constant: true
value: 5.0
type: Parameter

metaid_0000030
constant: true
value: 0.4
type: Parameter

metaid_0000064
constant: false
value: NaN
name: nucleotide sensitive k current
type: Parameter

metaid_0000079
constant: false
value: NaN
type: Parameter

metaid_0000101
constant: false
value: 0.01
type: Parameter

metaid_0000006
is: C00076
initial concentration: 0.1
constant: false
is: CHEBI:29108
has only substance units: false
name: cytosolic free ca concentration
type: Species
initial amount: NaN
in compartment: metaid_0000003
boundary condition: false

W3 CDTF: Thu Jul 05 17:44:08 BST 2012

metaid_0000085
constant: false
value: NaN
type: Parameter

metaid_0000045
constant: false
value: NaN
type: Parameter

metaid_0000017
constant: true
value: -75.0
type: Parameter

metaid_0000098
unit: 026669
name: millivolt
type: SBMLUnitsDef

metaid_0000031
constant: true
value: 0.01
type: Parameter

metaid_0000065
constant: false
value: NaN
name: erg like k current
type: Parameter

metaid_0000027
constant: true
value: 12.0
type: Parameter

026655
exponent: 1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000078
notes: Ca2+ dependent K+ current
is version of: GO:0015269

metaid_0000038
constant: true
value: 300000.0
type: Parameter

metaid_0000084
notes: Ca2+ leak is proportional to gradient between Ca2+ and ER
is version of: GO:0006816

metaid_0000007
type: Species
in compartment: metaid_0000003
has only substance units: false
boundary condition: false
name: ER ca concentration
is: C00076
initial concentration: 100.0
constant: false
initial amount: NaN
is: CHEBI:29108

metaid_0000102
constant: false
value: 0.46
type: Parameter

metaid_0000014
constant: true
value: 5.0
name: erg k current conductance
type: Parameter

metaid_0000042
constant: false
value: NaN
type: Parameter

metaid_0000032
constant: true
value: 5.0E-4
type: Parameter

metaid_0000062
constant: false
value: NaN
name: delayed rectifier k current
type: Parameter

metaid_0000028
constant: true
value: 0.4
type: Parameter

metaid_0000082
notes: Ca2+ flux into the ER via SERCA
is version of: GO:0015085
is version of: GO:0005388
is version of: GO:0005262

metaid_0000083
constant: false
value: NaN
type: Parameter

metaid_0000021
constant: true
value: 0.01
type: Parameter

metaid_0000073
notes: nucleotide-sensitive K+ current
is version of: GO:0015272

metaid_0000071
notes: Fraction of K(ca) channels activated by cytosolic Ca2+
is version of: GO:0015269

metaid_0000015
constant: true
value: 50.0
name: ca reversal potential
type: Parameter

metaid_0000043
constant: false
value: NaN
type: Parameter

metaid_0000033
constant: true
value: 0.5
type: Parameter

metaid_0000029
constant: true
value: 0.35
type: Parameter

metaid_0000063
constant: false
value: NaN
name: ca dependent k current
type: Parameter

metaid_0000081
constant: false
value: NaN
type: Parameter

metaid_0000020
constant: true
value: 4.5E-6
type: Parameter

metaid_0000100
constant: false
value: -60.0
type: Parameter

metaid_0000072
constant: false
value: NaN
type: Parameter

ORG:
  orgname: BNMC
n:
  given: Enuo
  family: He

W3 CDTF: Mon Jun 25 17:36:46 BST 2007