metaid_0000017
constant: true
value: 4.0
type: Parameter

metaid_0000034
event assignment: 286915
trigger: 286903
use values from trigger time: true
type: Event

286818
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000027
is version of: GO:0006816
is version of: GO:0051481
is version of: GO:0005388
reactant: 286806
type: Reaction
product: 286818
name: Pumping Ca into the InsP3-insensitive store
reversible: false
kinetic law: 286830
fast: false

286854
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

286879
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000024
is version of: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
type: Compartment

metaid_0000010
constant: true
value: 2.0
type: Parameter

metaid_0000004
is: C00076
initial concentration: 0.1
boundary condition: false
constant: false
name: Ca in the cytosol
has only substance units: false
initial amount: NaN
in compartment: metaid_0000024
type: Species
is: CHEBI:29108

metaid_0000014
constant: true
value: 10.0
type: Parameter

metaid_0000008
constant: true
value: 65.0
type: Parameter

metaid_0000033
notes: when flag=0, beta=0, flag=1, beta=beta_f*exp[-0.2*(t-tp)]
constant: false
value: 0.0
type: Parameter

metaid_0000018
constant: true
value: 4.0
name: stimulation time
type: Parameter

metaid_0000028
kinetic law: 286733
product: 286721
is version of: GO:0007204
is version of: GO:0006816
fast: false
reversible: false
name: InsP3 modulated release of Ca from the InsP3 sensitive store
type: Reaction

286903
persistant: true
initial value: true
type: Trigger

286782
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000023
is version of: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
type: Compartment

286842
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000007
constant: true
value: 7.3
type: Parameter

metaid_0000013
constant: true
value: 1.0
type: Parameter

metaid_0000015
constant: true
value: 2.0
type: Parameter

metaid_0000029
kinetic law: 286757
product: 286745
is version of: GO:0007204
is version of: GO:0006816
fast: false
reversible: false
name: Constant input of Ca from the extracellular medium
type: Reaction

metaid_0000032
kinetic law: 286891
reactant: 286879
is version of: GO:0051481
is version of: GO:0006816
fast: false
reversible: false
name: Transport of cytosolic ca into the extracellular medium
type: Reaction

metaid_0000019
notes: saturation function of the InsP3 receptor
constant: false
value: 0.0
type: Parameter

286806
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000026
kinetic law: 286794
product: 286782
reactant: 286770
is version of: GO:0007204
is version of: GO:0006816
fast: false
reversible: false
name: Leak Ca from pool to cytosol
type: Reaction

metaid_0000012
constant: true
value: 1.0
type: Parameter

metaid_0000031
kinetic law: 286867
product: 286854
reactant: 286842
is version of: GO:0007204
is version of: GO:0006816
fast: false
reversible: false
name: Release of Ca from the pool into the cytosol
type: Reaction

metaid_0000006
constant: true
value: 1.0
type: Parameter

metaid_0000016
constant: true
value: 2.0
type: Parameter

286770
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000035
unit: 286709
name: microM
type: SBMLUnitsDef

286721
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

BIOMD0000000117
parameter: metaid_0000018
is version of: GO:0048763
type: SBMLModel
reaction: metaid_0000031
parameter: metaid_0000007
parameter: metaid_0000033
parameter: metaid_0000013
parameter: metaid_0000017
parameter: metaid_0000006
volume units: metaid_0000084
compartment: metaid_0000025
substance units: metaid_0000035
name: Dupont1991_CaOscillation
compartment: metaid_0000023
modified:
  W3 CDTF: Thu Jul 05 17:48:14 BST 2012
reaction: metaid_0000029
is described by: http://identifiers.org/pubmed/1647878
reaction: metaid_0000026
reaction: metaid_0000028
rule: metaid_0000030
units def: metaid_0000035
time units: metaid_0000048
parameter: metaid_0000012
parameter: metaid_0000016
event: metaid_0000034
is version of: GO:0019722
parameter: metaid_0000009
reaction: metaid_0000032
notes: This model is according to the paper Signal-induced Ca2+ oscillations: Properties of a model based on Ca2+-induced Ca2+ release. Figure4B in the paper has been reproduced by RoadRunner and MathSBML. Damped Ca2+ oscillations elicited by a transient pulse of InsP3 applied intracellularly to a resting, non-oscillatory cell. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
length unit: length
created:
  W3 CDTF: Tue May 22 14:36:51 BST 2007
is: MODEL0466937756
area units: metaid_0000005
curated: true
species: metaid_0000004
reaction: metaid_0000027
creator:
  ORG:
    orgname: BNMC
  n:
    given: Enuo
    family: He
parameter: metaid_0000011
parameter: metaid_0000015
species: metaid_0000005
parameter: metaid_0000019
parameter: metaid_0000008
parameter: metaid_0000014
occurs in: http://identifiers.org/taxonomy/131567
compartment: metaid_0000024
parameter: metaid_0000010

metaid_0000025
is version of: GO:0044424
constant: true
size: 1.0
spatial dimensions: 3.0
type: Compartment

286709
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000009
constant: true
value: 500.0
type: Parameter

metaid_0000011
constant: true
value: 0.9
type: Parameter

metaid_0000005
has only substance units: false
is: CHEBI:29108
type: Species
is: C00076
constant: false
initial concentration: 1.4
name: Ca in the InsP3-insensitive pool
initial amount: NaN
in compartment: metaid_0000025
boundary condition: false

286745
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

metaid_0000030
notes: According to the legend of Figure4B, beta decays from the initial value beta_f=96% according to the equation beta=beta_f*exp[-0.2*(t-tp)]. and tp=4s.