metaid_0000007
constant: true
units: dimensionless
value: 2.0
type: Parameter

431266
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000033
unit: 431109
name: sec_inv
type: SBMLUnitsDef

metaid_0000003
constant: true
units: metaid_0000032
value: 1.0
type: Parameter

metaid_0000023
kinetic law: 431254
product: 431242
reactant: 431230
is: GO:0048763
is: GO:0007204
fast: false
reversible: false
name: ATP driven pumping into cytosol
type: Reaction

metaid_0000013
constant: true
units: metaid_0000034
value: 0.9
type: Parameter

431170
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000008
constant: true
units: metaid_0000034
value: 1.0
type: Parameter

metaid_0000010
constant: true
units: dimensionless
value: 2.0
type: Parameter

431134
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000018
is: C00076
is: CHEBI:29108
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.15
initial amount: NaN
in compartment: metaid_0000016
type: Species

metaid_0000009
constant: true
units: metaid_0000032
value: 500.0
type: Parameter

metaid_0000030
is: GO:0005783
constant: true
size: 1.0
spatial dimensions: 3.0
name: store
type: Compartment

431194
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

431097
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

431242
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000034
unit: 431134
unit: 431121
name: uM
type: SBMLUnitsDef

metaid_0000004
constant: true
units: metaid_0000032
value: 7.3
type: Parameter

metaid_0000024
kinetic law: 431290
product: 431278
reactant: 431266
is: GO:0007204
fast: false
reversible: false
name: Ca leak
type: Reaction

metaid_0000014
constant: true
units: metaid_0000033
value: 1.0
type: Parameter

metaid_0000020
kinetic law: 431158
product: 431146
is: GO:0006816
fast: false
reversible: false
name: Ca influx
type: Reaction

431073
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

431109
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

431121
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000025
kinetic law: 431314
reactant: 431302
is: GO:0006816
fast: false
reversible: false
name: Ca efflux
type: Reaction

431061
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

431302
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000019
is: C00076
is: CHEBI:29108
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.6
initial amount: NaN
in compartment: metaid_0000030
type: Species

BIOMD0000000098
compartment: metaid_0000030
parameter: metaid_0000013
parameter: metaid_0000012
units def: metaid_0000032
is version of: GO:0005220
reaction: metaid_0000022
compartment: metaid_0000016
is described by: http://identifiers.org/pubmed/2304911
substance units: metaid_0000031
parameter: metaid_0000008
reaction: metaid_0000023
created:
  W3 CDTF: Wed Mar 21 15:41:17 GMT 2007
length unit: length
notes: The model reproduces the time profile of cytosolic and intracellular calcium as depicted in the upper panel of Fig 2 in the paper. The model was successfully tested on MathSBML and Jarnac. This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2009 The BioModels Team. For more information see theterms of use . To cite BioModels Database, please useLe Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.
parameter: metaid_0000003
species: metaid_0000018
parameter: metaid_0000010
parameter: metaid_0000035
units def: metaid_0000031
name: Goldbeter1990_CalciumSpike_CICR
parameter: metaid_0000006
reaction: metaid_0000021
is: MODEL4519937652
creator:
  ORG:
    orgname: California Institute of Technology
  n:
    given: Harish
    family: Dharuri
parameter: metaid_0000007
units def: metaid_0000034
is version of: GO:0006816
modified:
  W3 CDTF: Fri Apr 20 20:24:28 BST 2012
reaction: metaid_0000020
curated: true
occurs in: http://identifiers.org/taxonomy/131567
type: SBMLModel
reaction: metaid_0000025
parameter: metaid_0000015
species: metaid_0000019
area units: metaid_0000005
volume units: metaid_0000004
parameter: metaid_0000005
reaction: metaid_0000024
parameter: metaid_0000009
units def: metaid_0000033
time units: metaid_0000173
parameter: metaid_0000014
parameter: metaid_0000004

metaid_0000035
constant: true
units: dimensionless
value: 4.0
type: Parameter

metaid_0000031
unit: 431061
name: micromole
type: SBMLUnitsDef

metaid_0000005
constant: true
units: dimensionless
value: 0.301
type: Parameter

metaid_0000021
kinetic law: 431182
product: 431170
is: GO:0005220
fast: false
reversible: false
name: InsP3 dependent Ca influx
type: Reaction

metaid_0000015
constant: true
units: metaid_0000033
value: 10.0
type: Parameter

431278
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000012
constant: true
units: metaid_0000034
value: 2.0
type: Parameter

431206
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

431146
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000006
constant: true
units: metaid_0000032
value: 65.0
type: Parameter

431230
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

431085
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000032
unit: 431097
unit: 431085
unit: 431073
name: uM_per_sec
type: SBMLUnitsDef

metaid_0000016
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
name: cytosol
type: Compartment

metaid_0000022
kinetic law: 431218
product: 431206
reactant: 431194
is: GO:0032470
fast: false
reversible: false
name: ATP driven Ca pumping into store
type: Reaction