This model was created according to the paper Inhibition of Adenylate Cyclase Is Mediated by the High Affinity Conformation of the alpha2-Adrenergic Receptor published in 1988. The figure4 (steady state curve) in the paper has been simulated having the same plot with Copasi 4.0.19 (development) and roadRunner(online).Because the initial concentration of R and D were not given in the paper ,so we gave it 1e-9 Mol/L and 1e-8 Mol/L respectively. Pay attention that the simulations of steady state concentration of species in arbitrary units are shown for figure4 and figure6 in the paper.
DRG_GTP dissociates(G protein activation)