metaid_0000072
kinetic law: 871733
reactant: 871721
has version: GO:0051261
fast: false
reversible: false
name: PCn nonspecific degradation
type: Reaction

416605
value: 0.1
name: Kdp
type: LocalParameter

871082
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

871757
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

871469
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

871745
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

metaid_0000032
kinetic law: 870535
reactant: 870523
is version of: GO:0051261
fast: false
reversible: false
name: Mc nonspecific degradation
type: Reaction

metaid_0000046
kinetic law: 870998
modifier: 870986
product: 870973
is version of: GO:0045893
fast: false
reversible: false
name: Mc synthesis
type: Reaction

metaid_0000027
kinetic law: 870379
modifier: 870367
product: 870355
is version of: GO:0006412
fast: false
reversible: false
name: Mb translated into protein
type: Reaction

870427
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

metaid_0000017
initial amount: NaN
type: Species
is version of: CHEBI:33699
has only substance units: false
name: Mp
notes: Initial concentration for Mp got from the value of curve at time=0 in the paper.
initial concentration: 2.5
constant: false
in compartment: metaid_0000009
boundary condition: false

870415
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

metaid_0000071
kinetic law: 871709
product: 871697
reactant: 871685
is version of: GO:0006470
fast: false
reversible: false
name: PCnp dephosphorylation
type: Reaction

870643
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

416604
value: 0.1
name: V2c
type: LocalParameter

metaid_0000059
kinetic law: 871349
reactant: 871337
is version of: GO:0008233
fast: false
reversible: false
name: PCnp specific degradation
type: Reaction

870824
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

metaid_0000031
kinetic law: 870511
modifier: 870499
product: 870487
is version of: GO:0006412
fast: false
reversible: false
name: Mc translated into protein
type: Reaction

metaid_0000045
kinetic law: 870961
reactant: 870949
is version of: GO:0051261
fast: false
reversible: false
name: Bnp nonspecific degradation
type: Reaction

metaid_0000028
kinetic law: 870403
reactant: 870391
is version of: GO:0051261
fast: false
reversible: false
name: Mb nonspecific degradation
type: Reaction

870487
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000018
has version: O15534
initial concentration: 0.0
initial amount: NaN
type: Species
name: Pc
boundary condition: false
has only substance units: false
constant: false
has version: O15055
in compartment: metaid_0000009
has version: P56645

870295
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

871070
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

870391
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

416517
value: 0.12
name: ksb
type: LocalParameter

871264
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

416603
value: 0.1
name: Kdp
type: LocalParameter

871553
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

metaid_0000029
kinetic law: 870439
product: 870427
reactant: 870415
is version of: GO:0006468
fast: false
reversible: false
name: Bc phosphorylation
type: Reaction

871118
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

metaid_0000009
is version of: GO:0005623
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

metaid_0000044
kinetic law: 870937
reactant: 870925
is version of: GO:0051261
fast: false
reversible: false
name: Bcp nonspecific degradation
type: Reaction

metaid_0000034
kinetic law: 870595
reactant: 870583
is version of: GO:0008233
fast: false
reversible: false
name: Ccp specific degradation
type: Reaction

metaid_0000015
boundary condition: false
initial amount: NaN
constant: false
has only substance units: false
initial concentration: 1.7
name: Mc
type: Species
in compartment: metaid_0000009
is part of: CHEBI:33699
notes: Initial concentration for Mc got from the value of the curve at time=0 in the paper.

870583
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

metaid_0000073
kinetic law: 871769
product: 871757
reactant: 871745
is version of: GO:0016311
is version of: GO:0006470
fast: false
reversible: false
name: PCcp dephosphorylation
type: Reaction

416569
value: 0.1
name: k8
type: LocalParameter

416549
value: 0.3
name: Kd
type: LocalParameter

416518
value: 0.01
name: kdmb
type: LocalParameter

416602
value: 0.2
name: V4b
type: LocalParameter

metaid_0000033
kinetic law: 870571
product: 870559
reactant: 870547
is version of: GO:0006468
fast: false
reversible: false
name: Cc phosphorylation
type: Reaction

871409
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

870884
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

metaid_0000043
kinetic law: 870896
reactant: 870884
is version of: GO:0051261
fast: false
reversible: false
name: PCnp nonspecific degradation
type: Reaction

416529
value: 0.1
name: Kp
type: LocalParameter

871143
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

416589
value: 0.5
name: V3b
type: LocalParameter

metaid_0000016
initial concentration: 0.0
type: Species
has version: Q16526
name: Ccp
initial amount: NaN
has only substance units: false
boundary condition: false
has version: Q8IV71
in compartment: metaid_0000009
constant: false

870715
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

416601
value: 0.1
name: Kdp
type: LocalParameter

871541
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

416568
value: 0.5
name: k7
type: LocalParameter

416515
value: 2.2
name: Kib
type: LocalParameter

416590
value: 0.1
name: Kp
type: LocalParameter

metaid_0000056
kinetic law: 871277
reactant: 871264
is version of: GO:0051261
fast: false
reversible: false
name: Ccp nonspecific degradation
type: Reaction

416528
value: 0.6
name: V1c
type: LocalParameter

metaid_0000036
kinetic law: 870667
modifier: 870655
product: 870643
is version of: GO:0006412
fast: false
reversible: false
name: Mp translated into protein
type: Reaction

870973
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

871445
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

871721
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

416600
value: 0.1
name: V2b
type: LocalParameter

metaid_0000055
kinetic law: 871252
reactant: 871240
is version of: GO:0051261
fast: false
reversible: false
name: Pcp nonspecific degradation
type: Reaction

416577
value: 0.12
name: kdnc
type: LocalParameter

metaid_0000069
kinetic law: 871637
product: 871625
reactant: 871613
is version of: GO:0006470
fast: false
reversible: false
name: Ccp dephosphorylation
type: Reaction

870607
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

870463
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

870703
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

416516
value: 2.0
type: LocalParameter

416591
value: 0.6
name: vdbn
type: LocalParameter

416567
value: 0.01
name: kdmp
type: LocalParameter

metaid_0000075
constant: false
value: NaN
name: LD
type: Parameter

416527
value: 0.01
name: kdmc
type: LocalParameter

metaid_0000035
kinetic law: 870631
modifier: 870619
product: 870607
is: GO:0045893
fast: false
reversible: false
name: Mp synthesis
type: Reaction

870751
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000049
kinetic law: 871106
product: 871094
reactant: 871082
reactant: 871070
is version of: GO:0043623
fast: false
reversible: true
name: Per_Cry and Clock_Bmal form inactive complex
type: Reaction

870848
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000068
kinetic law: 871601
product: 871589
reactant: 871577
is version of: GO:0006470
fast: false
reversible: false
name: Bnp dephosphorylation
type: Reaction

416566
value: 0.1
name: Kp
type: LocalParameter

metaid_0000058
kinetic law: 871325
reactant: 871313
is version of: GO:0051261
fast: false
reversible: false
name: PCc nonspecific degradation
type: Reaction

416550
value: 0.4
name: k1
type: LocalParameter

metaid_0000038
kinetic law: 870727
product: 870715
reactant: 870703
is version of: GO:0006468
fast: false
reversible: false
name: Pc phosphorylation
type: Reaction

metaid_0000019
has version: O15534
constant: false
has only substance units: false
has version: O15055
initial concentration: 0.0
in compartment: metaid_0000009
name: Pcp
type: Species
boundary condition: false
initial amount: NaN
has version: P56645

416526
value: 1.6
name: ksc
type: LocalParameter

871240
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000048
kinetic law: 871058
reactant: 871046
is version of: GO:0051261
fast: false
reversible: false
name: Mp nonspecific degradation
type: Reaction

871216
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

416579
value: 0.01
name: kdn
type: LocalParameter

metaid_0000067
kinetic law: 871565
product: 871553
reactant: 871541
is version of: GO:0006470
fast: false
reversible: false
name: Bcp dephosphorylation
type: Reaction

870860
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

metaid_0000077
constant: false
value: NaN
name: vsp
type: Parameter

metaid_0000057
kinetic law: 871301
reactant: 871289
is version of: GO:0051261
fast: false
reversible: false
name: PCcp nonspecific degradation
type: Reaction

416514
value: 1.0
type: LocalParameter

416552
value: 0.01
name: kdn
type: LocalParameter

871167
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

870763
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

871517
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

metaid_0000037
kinetic law: 870691
reactant: 870679
is version of: GO:0008233
fast: false
reversible: false
name: Pcp specific degradation
type: Reaction

416551
value: 0.2
name: k2
type: LocalParameter

416525
value: 0.2
name: k6
type: LocalParameter

416539
value: 0.3
name: Kd
type: LocalParameter

870679
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000047
kinetic law: 871034
product: 871022
reactant: 871010
is version of: GO:0006468
fast: false
reversible: false
name: PCn phosphorylation
type: Reaction

416523
value: 0.1
name: Kp
type: LocalParameter

416573
value: 0.4
name: Kmc
type: LocalParameter

870547
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

416533
value: 0.7
name: Kap
type: LocalParameter

metaid_0000065
kinetic law: 871505
reactant: 871493
is version of: GO:0008233
fast: false
reversible: false
name: In specific degradation
type: Reaction

416553
value: 0.01
name: kdn
type: LocalParameter

871289
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

416583
value: 0.01
name: kdn
type: LocalParameter

871625
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

416574
value: 1.1
name: vmp
type: LocalParameter

metaid_0000051
kinetic law: 871155
reactant: 871143
is version of: GO:0008233
fast: false
reversible: false
name: Mc specific degradation
type: Reaction

416610
value: 0.01
name: kdn
type: LocalParameter

416593
value: 0.01
name: kdn
type: LocalParameter

871493
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

416543
value: 0.2
name: k4
type: LocalParameter

416524
value: 0.4
name: k5
type: LocalParameter

metaid_0000010
initial concentration: 9.5
notes: The initial concentration of Mb got from the curve in the paper at time=0
boundary condition: false
in compartment: metaid_0000009
is version of: CHEBI:33699
initial amount: NaN
type: Species
name: Mb
constant: false
has only substance units: false

416572
value: 1.0
name: vmc
type: LocalParameter

871613
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

416562
value: 0.6
name: Kac
type: LocalParameter

metaid_0000039
kinetic law: 870775
product: 870763
reactant: 870751
reactant: 870739
is version of: GO:0043623
fast: false
reversible: true
name: Cc and Pc produce complex Per_Cry
type: Reaction

871022
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

870307
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000020
in compartment: metaid_0000009
has part: P56645
constant: false
has part: Q8IV71
boundary condition: false
initial concentration: 0.0
has part: Q16526
type: Species
name: PCc
has part: O15534
initial amount: NaN
has only substance units: false

416534
value: 0.6
name: ksp
type: LocalParameter

870559
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

metaid_0000066
kinetic law: 871529
reactant: 871517
is part of: GO:0051261
fast: false
reversible: false
name: Bn nonspecific degradation
type: Reaction

416563
value: 0.4
name: V3pc
type: LocalParameter

metaid_0000052
kinetic law: 871180
reactant: 871167
is part of: GO:0008233
fast: false
reversible: false
name: Mp specific degradation
type: Reaction

416544
value: 0.4
name: V1pc
type: LocalParameter

416592
value: 0.3
name: Kd
type: LocalParameter

871685
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

416611
value: 0.1
name: V2pc
type: LocalParameter

870949
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

870787
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

416540
value: 0.4
name: V1p
type: LocalParameter

metaid_0000021
initial concentration: 0.0
has part: Q16526
constant: false
has only substance units: false
in compartment: metaid_0000009
has part: O15534
has part: Q8IV71
type: Species
has part: P56645
initial amount: NaN
name: PCcp
boundary condition: false

BIOMD0000000078
reaction: metaid_0000046
reaction: metaid_0000066
has version: hsa04710
species: metaid_0000010
occurs in: http://identifiers.org/taxonomy/40674
is version of: GO:0009649
name: Inhibition of gene
is: MODEL4108701438
function def: metaid_0000004
rule: metaid_0000076
function def: metaid_0000006
reaction: metaid_0000040
reaction: metaid_0000060
reaction: metaid_0000041
reaction: metaid_0000061
substance units: metaid_0000008
reaction: metaid_0000055
reaction: metaid_0000035
species: metaid_0000024
reaction: metaid_0000036
reaction: metaid_0000056
curated: true
name: ceiling
reaction: metaid_0000070
species: metaid_0000015
type: SBMLModel
is described by: http://identifiers.org/pubmed/12775757
species: metaid_0000014
species: metaid_0000018
reaction: metaid_0000028
is derived from: BIOMD0000000021
reaction: metaid_0000029
parameter: metaid_0000077
reaction: metaid_0000044
species: metaid_0000021
reaction: metaid_0000064
reaction: metaid_0000045
reaction: metaid_0000065
volume units: metaid_0000004
reaction: metaid_0000039
reaction: metaid_0000059
notes: This model is described in the paper Toward a detailed computational model for the mammalian circadian clock . In this model only interlocked negative and positive regulation of Per, Cry, Bmal gene are involved. Some initial values were not provided, therefore they were chosen to fit the curves from the paper. Figure2C is re-produced by odeSolver. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
reaction: metaid_0000073
species: metaid_0000011
reaction: metaid_0000030
reaction: metaid_0000050
function def: metaid_0000003
name: Michaelis-Menten(irreversible)
function def: metaid_0000005
rule: metaid_0000078
compartment: metaid_0000009
time units: metaid_0000007
species: metaid_0000025
name: Activation of gene
area units: metaid_0000005
name: Leloup2003_CircClock_LD
species: metaid_0000012
reaction: metaid_0000048
reaction: metaid_0000068
reaction: metaid_0000049
reaction: metaid_0000069
species: metaid_0000016
reaction: metaid_0000027
parameter: metaid_0000075
species: metaid_0000019
reaction: metaid_0000063
reaction: metaid_0000043
reaction: metaid_0000033
reaction: metaid_0000053
reaction: metaid_0000034
reaction: metaid_0000054
units def: metaid_0000008
species: metaid_0000022
function def: metaid_0000074
reaction: metaid_0000071
reaction: metaid_0000072
reaction: metaid_0000026
length unit: length
species: metaid_0000023
reaction: metaid_0000042

416581
value: 0.01
name: kdn
type: LocalParameter

metaid_0000063
kinetic law: 871457
reactant: 871445
is version of: GO:0008233
fast: false
reversible: false
name: Bnp specific degradation
type: Reaction

870355
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

416555
value: 0.01
name: kdn
type: LocalParameter

416612
value: 0.1
name: Kdp
type: LocalParameter

416541
value: 0.1
name: Kp
type: LocalParameter

416595
value: 0.8
name: vdin
type: LocalParameter

metaid_0000053
kinetic law: 871204
reactant: 871192
is version of: GO:0051261
fast: false
reversible: false
name: Pc nonspecific degradation
type: Reaction

416576
value: 0.01
name: kdn
type: LocalParameter

870451
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

871010
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

416536
value: 0.7
name: vdpc
type: LocalParameter

871421
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000022
initial concentration: 1.0
has part: P56645
in compartment: metaid_0000009
has part: Q8IV71
boundary condition: false
has part: Q16526
name: PCn
type: Species
initial amount: NaN
has part: O15534
constant: false
has only substance units: false

416580
value: 0.01
name: kdn
type: LocalParameter

416556
value: 1.1
name: vsc
type: LocalParameter

metaid_0000064
kinetic law: 871481
reactant: 871469
is version of: GO:0051261
fast: false
reversible: false
name: In nonspecific degration
type: Reaction

871697
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

metaid_0000054
kinetic law: 871228
reactant: 871216
is version of: GO:0051261
fast: false
reversible: false
name: Cc nonspecific degradation
type: Reaction

416542
value: 0.4
name: k3
type: LocalParameter

871313
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

871385
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

416575
value: 0.31
name: Kmp
type: LocalParameter

metaid_0000041
kinetic law: 870836
reactant: 870824
is part of: GO:0008233
fast: false
reversible: false
name: PCcp specific degradation
type: Reaction

metaid_0000013
has version: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.9
initial amount: NaN
in compartment: metaid_0000009
name: Bn
type: Species

416588
value: 0.3
name: Kd
type: LocalParameter

416598
value: 0.3
name: Kd
type: LocalParameter

metaid_0000023
is version of: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: Bnp
type: Species

870739
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

871094
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

416547
value: 0.1
name: Kp
type: LocalParameter

416609
value: 0.1
name: Kdp
type: LocalParameter

870523
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

W3 CDTF: Tue Oct 17 16:43:58 BST 2006

871649
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000061
kinetic law: 871397
reactant: 871385
is version of: GO:0008233
fast: false
reversible: false
name: Bcp specific degradation
type: Reaction

870799
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

871577
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000042
kinetic law: 870872
product: 870860
reactant: 870848
is version of: GO:0000060
fast: false
reversible: true
name: PCc transfered into nuclear
type: Reaction

871661
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

416530
value: 0.7
name: vdcc
type: LocalParameter

416587
value: 0.5
name: vdbc
type: LocalParameter

metaid_0000014
in compartment: metaid_0000009
constant: false
initial amount: NaN
boundary condition: false
has version: Q16526
has version: Q8IV71
name: Cc
has only substance units: false
type: Species
initial concentration: 0.0

metaid_0000024
boundary condition: false
has part: Q16526
initial amount: NaN
constant: false
has part: P56645
has part: O15055
has only substance units: false
has part: Q8IV71
name: PCnp
has part: O15534
type: Species
initial concentration: 0.0
in compartment: metaid_0000009

416520
value: 0.5
name: V1b
type: LocalParameter

416548
value: 0.7
name: vdpcc
type: LocalParameter

416608
value: 0.1
name: V4pc
type: LocalParameter

871046
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000062
kinetic law: 871433
product: 871421
reactant: 871409
is version of: GO:0006468
fast: false
reversible: false
name: Bn phosphorylation
type: Reaction

416586
value: 0.01
name: kdn
type: LocalParameter

416531
value: 0.3
name: Kd
type: LocalParameter

416571
value: 0.4
name: Kmb
type: LocalParameter

metaid_0000011
in compartment: metaid_0000009
name: Bc
notes: In order to get the similar shape of the plot,we assigned 2nM as initial concentration for Bc
type: Species
initial amount: NaN
constant: false
boundary condition: false
has version: O00327
has only substance units: false
initial concentration: 2.0

metaid_0000025
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: In
type: Species

870925
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

416559
value: 4.0
type: LocalParameter

416607
value: 0.1
name: Kdp
type: LocalParameter

metaid_0000070
kinetic law: 871673
product: 871661
reactant: 871649
is version of: GO:0006470
fast: false
reversible: false
name: Pcp dephosphorylation
type: Reaction

metaid_0000012
has version: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: Bcp
type: Species

416585
value: 0.3
name: Kd
type: LocalParameter

metaid_0000040
kinetic law: 870812
product: 870799
reactant: 870787
is version of: GO:0006468
fast: false
reversible: false
name: PCc phosphorylation
type: Reaction

416532
value: 4.0
type: LocalParameter

871192
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000030
kinetic law: 870475
product: 870463
reactant: 870451
is version of: GO:0000060
fast: false
reversible: true
name: Bc transfered from cytosolic to nuclear
type: Reaction

871589
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

416570
value: 0.8
name: vmb
type: LocalParameter

871337
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

871361
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

416599
value: 0.01
name: kdn
type: LocalParameter

metaid_0000026
kinetic law: 870343
modifier: 870331
product: 870319
is version of: GO:0045892
fast: false
reversible: false
name: Mb synthesized
type: Reaction

870319
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

metaid_0000050
kinetic law: 871131
reactant: 871118
is version of: GO:0008233
fast: false
reversible: false
name: Mb specific degradation
type: Reaction

metaid_0000060
kinetic law: 871373
reactant: 871361
is version of: GO:0051261
fast: false
reversible: false
name: Bc nonspecific degradation
type: Reaction

416606
value: 0.3
name: V2p
type: LocalParameter

416584
value: 0.7
name: vdpcn
type: LocalParameter

ORG:
  orgname: University of Oxford
n:
  given: Enuo
  family: He

W3 CDTF: Wed Jul 11 19:31:48 BST 2012