metaid_0000036
kinetic law: 521508
modifier: 521496
product: 521484
is version of: GO:0006412
fast: false
reversible: false
name: Mp translated into protein
type: Reaction

metaid_0000060
kinetic law: 522211
reactant: 522199
is version of: GO:0044257
fast: false
reversible: false
name: Bc nonspecific degradation
type: Reaction

521982
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

522054
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

521592
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

064003
value: 0.1
name: V4pc
type: LocalParameter

063998
value: 0.1
name: Kdp
type: LocalParameter

063980
value: 0.5
name: vdbc
type: LocalParameter

metaid_0000050
kinetic law: 521969
reactant: 521956
is version of: GO:0008233
fast: false
reversible: false
name: Mb specific degradation
type: Reaction

metaid_0000026
kinetic law: 521183
modifier: 521171
product: 521159
is version of: GO:0045892
fast: false
reversible: false
name: Mb synthesized
type: Reaction

521641
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

522487
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

521291
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

063970
value: 0.12
name: kdnc
type: LocalParameter

063960
value: 0.5
name: k7
type: LocalParameter

metaid_0000035
kinetic law: 521472
modifier: 521460
product: 521448
is: GO:0045893
fast: false
reversible: false
name: Mp synthesis
type: Reaction

522127
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

522151
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

063997
value: 0.2
name: V4b
type: LocalParameter

064002
value: 0.1
name: Kdp
type: LocalParameter

522415
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

521556
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000025
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: In
type: Species

BIOMD0000000073
is version of: GO:0007623
reaction: metaid_0000057
species: metaid_0000013
reaction: metaid_0000044
species: metaid_0000017
function def: metaid_0000006
type: SBMLModel
reaction: metaid_0000056
volume units: metaid_0011035
compartment: metaid_0000009
reaction: metaid_0000073
occurs in: http://identifiers.org/taxonomy/40674
species: metaid_0000019
reaction: metaid_0000054
length unit: length
reaction: metaid_0000050
reaction: metaid_0000069
reaction: metaid_0000029
reaction: metaid_0000041
reaction: metaid_0000042
reaction: metaid_0000049
reaction: metaid_0000045
notes: This model is according to the paper Toward a detailed computational model for the mammalian circadian clock . In this model only interlocked negative and positive regulation of Per, Cry, Bmal gene are involved. Some initial values were not provided, therefore they were chosen to fit the curve from the paper. Figure2A re-produced by Copasi 4.0.19 and roadRunner online. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
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reaction: metaid_0000037
reaction: metaid_0000033
reaction: metaid_0000043
reaction: metaid_0000058
species: metaid_0000024
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function def: metaid_0000004
species: metaid_0000016
reaction: metaid_0000071
reaction: metaid_0000031
reaction: metaid_0000070
reaction: metaid_0000030
reaction: metaid_0000051
reaction: metaid_0000066
is: MODEL1109528188
reaction: metaid_0000063
species: metaid_0000021
reaction: metaid_0000047
reaction: metaid_0000064
name: Michaelis-Menten(irreversible)
reaction: metaid_0000060
name: mRNA translated into protein
reaction: metaid_0000039
name: Leloup2003_CircClock_DD
reaction: metaid_0000026
reaction: metaid_0000035
curated: true
species: metaid_0000023
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reaction: metaid_0000059
reaction: metaid_0000034
species: metaid_0000014
reaction: metaid_0000055
species: metaid_0000011
species: metaid_0000018
function def: metaid_0000005
species: metaid_0000015
area units: area
reaction: metaid_0000072
reaction: metaid_0000032
reaction: metaid_0000053
name: Inhibition of gene
reaction: metaid_0000065
reaction: metaid_0000052
reaction: metaid_0000061
is derived from: BIOMD0000000021
species: metaid_0000022
function def: metaid_0000003
reaction: metaid_0000067
reaction: metaid_0000027
name: Activation of gene
substance units: metaid_0000008

521701
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

063992
value: 0.01
name: kdn
type: LocalParameter

064001
value: 0.3
name: V2p
type: LocalParameter

521580
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000024
constant: false
initial concentration: 0.0
boundary condition: false
type: Species
has part: O15534
in compartment: metaid_0000009
name: PCnp
has only substance units: false
has part: Q16526
has part: Q8IV71
has part: P56645
initial amount: NaN

metaid_0000062
kinetic law: 522271
product: 522259
reactant: 522247
is version of: GO:0006468
fast: false
reversible: false
name: Bn phosphorylation
type: Reaction

521135
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

063972
value: 0.01
name: kdn
type: LocalParameter

metaid_0000038
kinetic law: 521568
product: 521556
reactant: 521544
is version of: GO:0006468
fast: false
reversible: false
name: Pc phosphorylation
type: Reaction

metaid_0000010
has only substance units: false
boundary condition: false
notes: The initial concentration of Mb got from the curve in the paper at time=0
initial amount: NaN
type: Species
constant: false
name: Mb
in compartment: metaid_0000009
initial concentration: 9.0
is version of: CHEBI:33699

063940
value: 0.3
name: Kd
type: LocalParameter

521195
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

522560
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

064000
value: 0.1
name: Kdp
type: LocalParameter

063991
value: 0.3
name: Kd
type: LocalParameter

063999
value: 0.1
name: V2c
type: LocalParameter

metaid_0000061
kinetic law: 522235
reactant: 522223
is version of: GO:0008233
fast: false
reversible: false
name: Bcp specific degradation
type: Reaction

521544
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

521904
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

metaid_0000023
has version: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: Bnp
type: Species

522427
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

063971
value: 0.01
name: kdn
type: LocalParameter

521629
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000037
kinetic law: 521532
reactant: 521520
is version of: GO:0008233
fast: false
reversible: false
name: Pcp specific degradation
type: Reaction

metaid_0000064
kinetic law: 522319
reactant: 522307
is version of: GO:0044257
fast: false
reversible: false
name: In nonspecific degration
type: Reaction

063994
value: 0.1
name: V2b
type: LocalParameter

metaid_0000022
initial amount: NaN
boundary condition: false
has part: O15534
initial concentration: 1.0
constant: false
in compartment: metaid_0000009
has part: Q16526
has part: P56645
has only substance units: false
has part: Q8IV71
type: Species
name: PCn

522596
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

521665
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

063959
value: 0.01
name: kdmp
type: LocalParameter

metaid_0000054
kinetic law: 522067
reactant: 522054
is version of: GO:0044257
fast: false
reversible: false
name: Cc nonspecific degradation
type: Reaction

063984
value: 0.1
name: Kp
type: LocalParameter

metaid_0000032
kinetic law: 521376
reactant: 521364
is version of: GO:0044257
fast: false
reversible: false
name: Mc nonspecific degradation
type: Reaction

063942
value: 0.1
name: Kp
type: LocalParameter

metaid_0000012
has version: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
name: Bcp
type: Species

521839
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

063932
value: 0.3
name: Kd
type: LocalParameter

521267
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

metaid_0000063
kinetic law: 522295
reactant: 522283
is version of: GO:0008233
fast: false
reversible: false
name: Bnp specific degradation
type: Reaction

metaid_0000021
has part: Q8IV71
type: Species
has part: P56645
has only substance units: false
boundary condition: false
constant: false
has part: O15534
name: PCcp
has part: Q16526
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000009
has part: O15055

521364
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

521303
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

521800
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

063983
value: 0.5
name: V3b
type: LocalParameter

metaid_0000031
kinetic law: 521352
modifier: 521340
product: 521327
is version of: GO:0006412
fast: false
reversible: false
name: Mc translated into protein
type: Reaction

metaid_0000053
kinetic law: 522042
reactant: 522030
is version of: GO:0044257
fast: false
reversible: false
name: Pc nonspecific degradation
type: Reaction

metaid_0000011
type: Species
has only substance units: false
in compartment: metaid_0000009
constant: false
notes: In order to get the similar shape of the plot,we assigned 2nM as initial concentration for Bc
initial amount: NaN
boundary condition: false
initial concentration: 2.0
name: Bc
has version: O00327

metaid_0000073
kinetic law: 522608
product: 522596
reactant: 522584
is version of: GO:0016311
is version of: GO:0006470
fast: false
reversible: false
name: PCcp dephosphorylation
type: Reaction

522331
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

063941
value: 0.4
name: V1p
type: LocalParameter

521956
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

063931
value: 0.7
name: vdcc
type: LocalParameter

metaid_0000066
kinetic law: 522367
reactant: 522355
is version of: GO:0044257
fast: false
reversible: false
name: Bn nonspecific degradation
type: Reaction

063996
value: 0.1
name: Kdp
type: LocalParameter

metaid_0000020
in compartment: metaid_0000009
initial amount: NaN
has part: O15055
has part: P56645
type: Species
boundary condition: false
has part: O15534
name: PCc
has only substance units: false
has part: Q16526
initial concentration: 0.0
constant: false

521604
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000052
kinetic law: 522018
reactant: 522006
is version of: GO:0008233
fast: false
reversible: false
name: Mp specific degradation
type: Reaction

063982
value: 0.3
name: Kd
type: LocalParameter

metaid_0000034
kinetic law: 521436
reactant: 521424
is version of: GO:0008233
fast: false
reversible: false
name: Ccp specific degradation
type: Reaction

522499
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

063957
value: 0.4
name: V3pc
type: LocalParameter

522584
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

521917
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

063944
value: 0.2
name: k4
type: LocalParameter

522259
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000014
has only substance units: false
boundary condition: false
in compartment: metaid_0000009
initial concentration: 0.0
initial amount: NaN
has version: Q8IV71
type: Species
has version: Q16526
constant: false
name: Cc

metaid_0000072
kinetic law: 522572
reactant: 522560
is version of: GO:0044257
fast: false
reversible: false
name: PCn nonspecific degradation
type: Reaction

063930
value: 0.1
name: Kp
type: LocalParameter

metaid_0000065
kinetic law: 522343
reactant: 522331
is part of: GO:0008233
fast: false
reversible: false
name: In specific degradation
type: Reaction

metaid_0000051
kinetic law: 521994
reactant: 521982
is version of: GO:0008233
fast: false
reversible: false
name: Mc specific degradation
type: Reaction

521255
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

521327
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

063958
value: 0.1
name: Kp
type: LocalParameter

521878
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000033
kinetic law: 521412
product: 521400
reactant: 521388
is version of: GO:0006468
fast: false
reversible: false
name: Cc phosphorylation
type: Reaction

521400
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

522079
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000013
is: O00327
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.9
initial amount: NaN
in compartment: metaid_0000009
name: Bn
type: Species

063943
value: 0.4
name: k3
type: LocalParameter

522307
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

063918
value: 0.5
name: V1b
type: LocalParameter

metaid_0000071
kinetic law: 522548
product: 522535
reactant: 522523
is version of: GO:0006470
fast: false
reversible: false
name: PCnp dephosphorylation
type: Reaction

063916
value: 0.01
name: kdmb
type: LocalParameter

metaid_0000070
kinetic law: 522511
product: 522499
reactant: 522487
is version of: GO:0006470
fast: false
reversible: false
name: Pcp dephosphorylation
type: Reaction

063965
value: 0.4
name: Kmc
type: LocalParameter

063955
value: 4.0
type: LocalParameter

521930
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

522283
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

064010
value: 0.1
name: Kdp
type: LocalParameter

521749
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

063975
value: 0.01
name: kdn
type: LocalParameter

063946
value: 0.1
name: Kp
type: LocalParameter

metaid_0000016
has version: Q16526
boundary condition: false
constant: false
type: Species
in compartment: metaid_0000009
has only substance units: false
initial amount: NaN
has version: Q8IV71
initial concentration: 0.0
name: Ccp

metaid_0000045
kinetic law: 521787
reactant: 521774
is version of: GO:0044257
fast: false
reversible: false
name: Bnp nonspecific degradation
type: Reaction

metaid_0000055
kinetic law: 522091
reactant: 522079
is version of: GO:0044257
fast: false
reversible: false
name: Pcp nonspecific degradation
type: Reaction

063985
value: 0.6
name: vdbn
type: LocalParameter

521774
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

063966
value: 1.1
name: vmp
type: LocalParameter

063915
value: 0.12
name: ksb
type: LocalParameter

063945
value: 0.4
name: V1pc
type: LocalParameter

063925
value: 0.01
name: kdmc
type: LocalParameter

063956
value: 0.6
name: Kac
type: LocalParameter

522247
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

521689
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

metaid_0000040
kinetic law: 521653
product: 521641
reactant: 521629
is version of: GO:0006468
fast: false
reversible: false
name: PCc phosphorylation
type: Reaction

metaid_0000015
is version of: CHEBI:33699
name: Mc
notes: Initial concentration for Mc got from the value of the curve at time=0 in the paper.
initial concentration: 1.4
constant: false
type: Species
in compartment: metaid_0000009
boundary condition: false
has only substance units: false
initial amount: NaN

063976
value: 0.7
name: vdpcn
type: LocalParameter

metaid_0000046
kinetic law: 521826
modifier: 521813
product: 521800
is version of: GO:0045893
fast: false
reversible: false
name: Mc synthesis
type: Reaction

063986
value: 0.3
name: Kd
type: LocalParameter

metaid_0000056
kinetic law: 522115
reactant: 522103
is version of: GO:0044257
fast: false
reversible: false
name: Ccp nonspecific degradation
type: Reaction

metaid_0000030
kinetic law: 521315
product: 521303
reactant: 521291
is version of: GO:0000060
fast: false
reversible: true
name: Bc transfered from cytosolic to nuclear
type: Reaction

063934
value: 4.0
type: LocalParameter

063967
value: 0.31
name: Kmp
type: LocalParameter

063914
value: 2.0
type: LocalParameter

521424
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

063953
value: 0.01
name: kdn
type: LocalParameter

063948
value: 0.3
name: Kd
type: LocalParameter

metaid_0000018
constant: false
boundary condition: false
type: Species
initial amount: NaN
in compartment: metaid_0000009
has version: P56645
has version: O15534
has only substance units: false
initial concentration: 0.0
name: Pc
has version: O15055

522175
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

metaid_0000041
kinetic law: 521677
reactant: 521665
is version of: GO:0008233
fast: false
reversible: false
name: PCcp specific degradation
type: Reaction

metaid_0000043
kinetic law: 521737
reactant: 521725
is version of: GO:0044257
fast: false
reversible: false
name: PCnp nonspecific degradation
type: Reaction

metaid_0000057
kinetic law: 522139
reactant: 522127
is version of: GO:0044257
fast: false
reversible: false
name: PCcp nonspecific degradation
type: Reaction

063987
value: 0.01
name: kdn
type: LocalParameter

063933
value: 1.5
name: vsp
type: LocalParameter

063913
value: 2.2
name: Kib
type: LocalParameter

063954
value: 1.1
name: vsc
type: LocalParameter

063927
value: 0.6
name: V1c
type: LocalParameter

metaid_0000044
kinetic law: 521761
reactant: 521749
is version of: GO:0044257
fast: false
reversible: false
name: Bcp nonspecific degradation
type: Reaction

063947
value: 0.7
name: vdpcc
type: LocalParameter

metaid_0000017
has only substance units: false
is version of: CHEBI:33699
constant: false
name: Mp
type: Species
notes: Initial concentration for Mp got from the value of curve at time=0 in the paper.
initial amount: NaN
initial concentration: 1.6
boundary condition: false
in compartment: metaid_0000009

522006
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

522030
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

metaid_0000042
kinetic law: 521713
product: 521701
reactant: 521689
is version of: GO:0000060
fast: false
reversible: true
name: PCc transfered into nuclear
type: Reaction

063974
value: 0.01
name: kdn
type: LocalParameter

063968
value: 0.01
name: kdn
type: LocalParameter

522355
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

metaid_0000058
kinetic law: 522163
reactant: 522151
is version of: GO:0044257
fast: false
reversible: false
name: PCc nonspecific degradation
type: Reaction

063951
value: 0.01
name: kdn
type: LocalParameter

metaid_0000049
kinetic law: 521943
product: 521930
reactant: 521917
reactant: 521904
is version of: GO:0043623
fast: false
reversible: true
name: Per_Cry and Clock_Bmal form inactive complex
type: Reaction

metaid_0000069
kinetic law: 522475
product: 522463
reactant: 522451
is version of: GO:0006470
fast: false
reversible: false
name: Ccp dephosphorylation
type: Reaction

521725
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

522523
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

metaid_0000059
kinetic law: 522187
reactant: 522175
is version of: GO:0008233
fast: false
reversible: false
name: PCnp specific degradation
type: Reaction

063961
value: 0.1
name: k8
type: LocalParameter

063989
value: 0.8
name: vdin
type: LocalParameter

522103
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

063912
value: 1.0
type: LocalParameter

522391
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

063922
value: 0.4
name: k5
type: LocalParameter

521231
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

522463
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

063952
value: 0.01
name: kdn
type: LocalParameter

521159
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

521852
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

metaid_0000039
kinetic law: 521617
product: 521604
reactant: 521592
reactant: 521580
is version of: GO:0043623
fast: false
reversible: true
name: Cc and Pc produce complex Per_Cry
type: Reaction

metaid_0000029
kinetic law: 521279
product: 521267
reactant: 521255
is version of: GO:0006468
fast: false
reversible: false
name: Bc phosphorylation
type: Reaction

521484
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

063962
value: 0.8
name: vmb
type: LocalParameter

metaid_0000009
is version of: GO:0005622
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

063939
value: 0.7
name: vdpc
type: LocalParameter

064007
value: 0.1
name: V2pc
type: LocalParameter

063921
value: 0.1
name: Kp
type: LocalParameter

metaid_0000019
name: Pcp
in compartment: metaid_0000009
has version: O15534
has version: P56645
initial amount: NaN
constant: false
type: Species
boundary condition: false
has only substance units: false
initial concentration: 0.0
has version: O15055

522223
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

063949
value: 0.4
name: k1
type: LocalParameter

063924
value: 1.6
name: ksc
type: LocalParameter

metaid_0000067
kinetic law: 522403
product: 522391
reactant: 522379
is version of: GO:0006470
fast: false
reversible: false
name: Bcp dephosphorylation
type: Reaction

522535
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

522199
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

063963
value: 0.4
name: Kmb
type: LocalParameter

metaid_0000028
kinetic law: 521243
reactant: 521231
is version of: GO:0044257
fast: false
reversible: false
name: Mb nonspecific degradation
type: Reaction

064004
value: 0.1
name: Kdp
type: LocalParameter

521388
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

063938
value: 0.6
name: ksp
type: LocalParameter

521448
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

522451
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

521520
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

metaid_0000047
kinetic law: 521865
product: 521852
reactant: 521839
is version of: GO:0006468
fast: false
reversible: false
name: PCn phosphorylation
type: Reaction

063977
value: 0.3
name: Kd
type: LocalParameter

metaid_0000068
kinetic law: 522439
product: 522427
reactant: 522415
is version of: GO:0006470
fast: false
reversible: false
name: Bnp dephosphorylation
type: Reaction

metaid_0000048
kinetic law: 521891
reactant: 521878
is version of: GO:0044257
fast: false
reversible: false
name: Mp nonspecific degradation
type: Reaction

063950
value: 0.2
name: k2
type: LocalParameter

522379
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

063964
value: 1.0
name: vmc
type: LocalParameter

metaid_0000027
kinetic law: 521219
modifier: 521207
product: 521195
is version of: GO:0006412
fast: false
reversible: false
name: Mb translated into protein
type: Reaction

521147
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

064005
value: 0.01
name: kdn
type: LocalParameter

063937
value: 0.7
name: Kap
type: LocalParameter

063978
value: 0.01
name: kdn
type: LocalParameter

063923
value: 0.2
name: k6
type: LocalParameter

W3 CDTF: Tue Oct 17 16:43:58 BST 2006

orgname: University of Oxford

given: Enuo
family: He

W3 CDTF: Wed Jul 11 19:26:59 BST 2012