metaid_0000042
type: Species
name: Protein2
constant: false
initial concentration: 0.0
is version of: C00017
has only substance units: false
is version of: CHEBI:36080
boundary condition: false
in compartment: metaid_0000003
initial amount: NaN

850789
units: metaid_0000091
value: 1.0E7
type: LocalParameter

850369
units: metaid_0000091
value: 10000.0
type: LocalParameter

847163
units: metaid_0000089
value: 1.14
type: LocalParameter

847988
units: metaid_0000089
value: 0.002
type: LocalParameter

metaid_0000062
type: Reaction
reactant: 848571
name: Lactate dehydrogenase
is: REACT 178
reversible: true
kinetic law: 848608
product: 848596
is version of: http://identifiers.org/ec-code/1.1.1.27
reactant: 848559
is: R00703
product: 848583
fast: false

847599
units: metaid_0000089
value: 0.114
type: LocalParameter

847794
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

metaid_0000041
initial concentration: 0.0
in compartment: metaid_0000003
initial amount: NaN
has part: CHEBI:18009
type: Species
has part: CHEBI:36080
name: Protein2 bound NADP
boundary condition: false
has part: C00017
constant: false
has part: C00006
has only substance units: false

849644
units: metaid_0000089
value: 2.2
type: LocalParameter

850465
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

849367
units: metaid_0000090
value: 90.0
type: LocalParameter

848860
units: metaid_0000089
value: 0.09
type: LocalParameter

847648
units: metaid_0000089
value: 0.176
type: LocalParameter

848523
units: dimensionless
value: 19.0
type: LocalParameter

849801
units: metaid_0000089
value: 0.00496
type: LocalParameter

metaid_0000061
modifier: 848450
reactant: 848402
reactant: 848390
type: Reaction
is: REACT 1911
product: 848426
reversible: true
name: Pyruvate kinase
modifier: 848438
fast: false
product: 848414
is version of: http://identifiers.org/ec-code/2.7.1.40
kinetic law: 848463
is: R00200

metaid_0000040
initial concentration: 0.024
initial amount: NaN
constant: false
in compartment: metaid_0000003
boundary condition: false
has part: CHEBI:36080
has part: C00017
name: Protein1 bound NADPH
has part: CHEBI:16474
has part: C00005
has only substance units: false
type: Species

846957
units: metaid_0000089
value: 1.7
type: LocalParameter

metaid_0000030
in compartment: metaid_0000003
initial concentration: 0.0127
name: Xylulose 5-phosphate
is: C00231
type: Species
constant: false
has only substance units: false
boundary condition: false
initial amount: NaN
is: CHEBI:16332

849657
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

849741
units: metaid_0000089
value: 0.4177
type: LocalParameter

850621
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

847976
units: metaid_0000089
value: 0.35
type: LocalParameter

BIOMD0000000070
reaction: metaid_0000062
species: metaid_0000025
species: metaid_0000038
species: metaid_0000029
species: metaid_0000011
reaction: metaid_0000049
reaction: metaid_0000058
species: metaid_0000024
species: metaid_0000035
reaction: metaid_0000073
species: metaid_0000028
species: metaid_0000039
reaction: metaid_0000085
species: metaid_0000041
species: metaid_0000036
species: metaid_0000005
reaction: metaid_0000053
reaction: metaid_0000068
reaction: metaid_0000083
reaction: metaid_0000070
species: metaid_0000022
species: metaid_0000033
species: metaid_0000043
reaction: metaid_0000079
reaction: metaid_0000066
reaction: metaid_0000051
species: metaid_0000019
reaction: metaid_0000063
species: metaid_0000046
units def: metaid_0000087
has part: REACT 1859
species: metaid_0000009
reaction: metaid_0000077
name: Holzhutter2004_Erythrocyte_Metabolism
reaction: metaid_0000061
reaction: metaid_0000057
volume units: metaid_0000323
species: metaid_0000026
species: metaid_0000037
species: metaid_0000047
reaction: metaid_0000074
has part: GO:0006096
reaction: metaid_0000055
reaction: metaid_0000067
species: metaid_0000042
area units: area
species: metaid_0000012
curated: true
species: metaid_0000006
species: metaid_0000016
length unit: length
reaction: metaid_0000072
units def: metaid_0000091
type: SBMLModel
time units: metaid_0000088
reaction: metaid_0000065
has part: hsa00010
reaction: metaid_0000052
species: metaid_0000040
species: metaid_0000044
species: metaid_0000004
compartment: metaid_0000003
reaction: metaid_0000082
species: metaid_0000010
has part: hsa00480
occurs in: http://identifiers.org/taxonomy/9606
reaction: metaid_0000078
species: metaid_0000007
reaction: metaid_0000050
species: metaid_0000034
reaction: metaid_0000059
reaction: metaid_0000080
has part: REACT 1383
notes: . . . SBML level 2 code generated for the JWS Online project by Jacky Snoep using PySCeS Run this model online at http://jjj.biochem.sun.ac.za To cite JWS Online please refer to: Olivier, B.G. and Snoep, J.L. (2004) Web-based modelling using JWS Online , Bioinformatics, 20:2143-2144 . . . . . . Biomodels Curation The model simulates the flux values as given for "kinetic model" in Table 1 of the paper. The model was successfully tested on Jarnac.
has part: hsa00030
reaction: metaid_0000076
has part: GO:0006098
reaction: metaid_0000060
species: metaid_0000013
species: metaid_0000023

848378
units: metaid_0000089
value: 1.0
type: LocalParameter

metaid_0000050
modifier: 847079
modifier: 847067
is: REACT 1318
reversible: true
product: 847043
is: R00299
name: Hexokinase
modifier: 847055
kinetic law: 847091
is version of: http://identifiers.org/ec-code/2.7.1.2
reactant: 847007
product: 847031
reactant: 847019
type: Reaction
fast: false

metaid_0000060
is: R00658
reactant: 848305
reversible: true
type: Reaction
kinetic law: 848329
name: Enolase
is: REACT 1400
product: 848317
is version of: http://identifiers.org/ec-code/4.2.1.11
fast: false

849017
units: metaid_0000090
value: 162.0
type: LocalParameter

847151
units: metaid_0000090
value: 33.2
type: LocalParameter

850176
units: dimensionless
value: 1.2
type: LocalParameter

847612
units: metaid_0000089
value: 0.0572
type: LocalParameter

850453
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

849813
units: dimensionless
value: 48.8
type: LocalParameter

848511
units: metaid_0000089
value: 0.474
type: LocalParameter

847273
units: metaid_0000090
value: 935.0
type: LocalParameter

848872
units: metaid_0000089
value: 0.08
type: LocalParameter

846920
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

850477
stoichiometry: 1.0
species: metaid_0000035
type: SpeciesReference

848366
units: metaid_0000089
value: 1.0
type: LocalParameter

847770
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

847964
units: metaid_0000090
value: 5000.0
type: LocalParameter

metaid_0000066
is: R00835
reactant: 848908
modifier: 848956
fast: false
is version of: http://identifiers.org/ec-code/1.1.1.49
modifier: 848981
product: 848944
reactant: 848920
name: Glucose 6-phosphate dehydrogenase
has version: REACT 1125
product: 848932
modifier: 848968
has version: REACT 1868
modifier: 848993
reversible: true
type: Reaction
kinetic law: 849005

849669
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

849753
units: metaid_0000089
value: 0.3055
type: LocalParameter

metaid_0000052
type: Reaction
product: 847357
modifier: 847369
kinetic law: 847418
is: REACT 736
fast: false
modifier: 847381
name: Phosphofructokinase
is version of: http://identifiers.org/ec-code/2.7.1.11
reactant: 847333
is: R00756
reactant: 847321
modifier: 847393
reversible: true
product: 847345
modifier: 847406

850765
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

847188
units: metaid_0000089
value: 1.03
type: LocalParameter

849957
units: dimensionless
value: 0.8683
type: LocalParameter

847007
stoichiometry: 1.0
species: metaid_0000004
type: SpeciesReference

850188
units: metaid_0000089
value: 0.00184
type: LocalParameter

847709
units: dimensionless
value: 0.0407
type: LocalParameter

metaid_0000065
reversible: true
type: Reaction
name: Adenylate kinase
kinetic law: 848836
product: 848812
reactant: 848800
is: R00127
product: 848824
reactant: 848788
is version of: http://identifiers.org/ec-code/2.7.4.3
fast: false

848317
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

847624
units: metaid_0000089
value: 0.1906
type: LocalParameter

848668
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

metaid_0000051
reversible: true
is: R00771
is: REACT 1164
fast: false
kinetic law: 847261
product: 847249
reactant: 847236
is version of: http://identifiers.org/ec-code/5.3.1.9
type: Reaction
name: Glucosephosphate isomerase

849270
units: metaid_0000089
value: 0.154
type: LocalParameter

847309
units: metaid_0000089
value: 0.071
type: LocalParameter

847782
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

848354
units: dimensionless
value: 1.7
type: LocalParameter

848268
units: dimensionless
value: 0.145
type: LocalParameter

849765
units: dimensionless
value: 0.00774
type: LocalParameter

metaid_0000064
type: Reaction
kinetic law: 848764
fast: false
reactant: 848728
is version of: http://identifiers.org/ec-code/3.6.1.3
is: R00086
name: ATPase
reversible: true
product: 848740
product: 848752

metaid_0000054
is: REACT 775
name: Triosephosphate isomerase
is: R01015
is version of: http://identifiers.org/ec-code/5.3.1.1
fast: false
product: 847672
type: Reaction
reactant: 847660
kinetic law: 847685
reversible: true

850030
stoichiometry: 1.0
species: metaid_0000044
type: SpeciesReference

850429
units: metaid_0000091
value: 10000.0
type: LocalParameter

848475
units: metaid_0000090
value: 570.0
type: LocalParameter

847697
units: metaid_0000090
value: 5456.600098
type: LocalParameter

847103
units: dimensionless
value: 1.0
type: LocalParameter

849608
units: metaid_0000090
value: 730.0
type: LocalParameter

847176
units: metaid_0000089
value: 3900.0
type: LocalParameter

849969
units: metaid_0000089
value: 0.006095
type: LocalParameter

847019
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000079
kinetic law: 850489
product: 850477
product: 850465
reactant: 850453
is version of: GO:0006754
fast: false
reversible: true
name: MgATP dissociation
type: Reaction

849282
units: metaid_0000089
value: 0.058
type: LocalParameter

metaid_0000063
fast: false
reversible: true
reactant: 848644
type: Reaction
kinetic law: 848692
is version of: http://identifiers.org/ec-code/1.1.1.27
product: 848668
reactant: 848656
product: 848680
name: Lactate dehydrogenase

850573
units: metaid_0000091
value: 1.0E7
type: LocalParameter

metaid_0000053
is: R01070
product: 847550
product: 847538
is: REACT 1602
reactant: 847526
kinetic law: 847562
name: Aldolase
reversible: true
fast: false
type: Reaction
is version of: http://identifiers.org/ec-code/4.1.2.13

847636
units: metaid_0000089
value: 0.0364
type: LocalParameter

850909
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

850585
units: metaid_0000089
value: 0.76
type: LocalParameter

849294
units: metaid_0000089
value: 0.0045
type: LocalParameter

849693
stoichiometry: 1.0
species: metaid_0000032
type: SpeciesReference

849330
stoichiometry: 2.0
species: metaid_0000029
type: SpeciesReference

849933
units: dimensionless
value: 0.4653
type: LocalParameter

848571
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

847466
units: metaid_0000089
value: 0.068
type: LocalParameter

849849
stoichiometry: 1.0
species: metaid_0000033
type: SpeciesReference

849138
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

847115
units: metaid_0000089
value: 0.1
type: LocalParameter

848908
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

850237
units: dimensionless
value: 0.0287
type: LocalParameter

848218
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

850657
units: metaid_0000089
value: 16.64
type: LocalParameter

850091
units: metaid_0000089
value: 0.57
type: LocalParameter

849234
units: metaid_0000089
value: 0.018
type: LocalParameter

848109
units: metaid_0000089
value: 0.04
type: LocalParameter

849777
units: metaid_0000089
value: 12.432
type: LocalParameter

850741
stoichiometry: 1.0
species: metaid_0000038
type: SpeciesReference

847818
units: metaid_0000090
value: 4300.0
type: LocalParameter

846872
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

847904
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

847660
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

848256
units: metaid_0000090
value: 2000.0
type: LocalParameter

848704
units: metaid_0000092
value: 243.4
type: LocalParameter

847031
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

849681
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

849342
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

850597
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

848305
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

847127
units: metaid_0000090
value: 15.8
type: LocalParameter

849945
units: metaid_0000089
value: 0.1733
type: LocalParameter

848583
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

847478
units: dimensionless
value: 0.001072
type: LocalParameter

849789
units: dimensionless
value: 0.41139
type: LocalParameter

850753
stoichiometry: 1.0
species: metaid_0000039
type: SpeciesReference

846908
stoichiometry: 1.0
species: metaid_0000047
type: SpeciesReference

850249
units: metaid_0000089
value: 3.0E-4
type: LocalParameter

850669
stoichiometry: 1.0
species: metaid_0000037
type: SpeciesReference

849391
units: metaid_0000089
value: 0.00852
type: LocalParameter

849222
units: metaid_0000089
value: 0.01
type: LocalParameter

848206
units: metaid_0000089
value: 0.2
type: LocalParameter

848716
units: dimensionless
value: 14181.8
type: LocalParameter

846860
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

847916
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

847672
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

W3 CDTF: Thu Sep 07 16:04:38 BST 2006

850549
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

848884
units: dimensionless
value: 0.25
type: LocalParameter

849114
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

849825
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

847139
units: metaid_0000089
value: 1.44
type: LocalParameter

848728
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

849427
units: dimensionless
value: 1.04
type: LocalParameter

847502
units: metaid_0000089
value: 0.44
type: LocalParameter

850441
units: dimensionless
value: 1.0
type: LocalParameter

849620
units: dimensionless
value: 3.0
type: LocalParameter

848596
stoichiometry: 1.0
species: metaid_0000013
type: SpeciesReference

847928
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

849089
units: metaid_0000089
value: 2.289
type: LocalParameter

849029
units: metaid_0000089
value: 0.0667
type: LocalParameter

849210
units: metaid_0000090
value: 1575.0
type: LocalParameter

848049
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

847321
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

849837
stoichiometry: 1.0
species: metaid_0000032
type: SpeciesReference

848896
units: metaid_0000089
value: 0.11
type: LocalParameter

849921
units: metaid_0000089
value: 0.04765
type: LocalParameter

849126
stoichiometry: 1.0
species: metaid_0000027
type: SpeciesReference

850163
units: metaid_0000090
value: 23.5
type: LocalParameter

849632
units: metaid_0000089
value: 0.78
type: LocalParameter

849439
stoichiometry: 2.0
species: metaid_0000029
type: SpeciesReference

848230
stoichiometry: 1.0
species: metaid_0000018
type: SpeciesReference

847043
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

849981
units: dimensionless
value: 2.524
type: LocalParameter

846945
units: metaid_0000090
value: 33.6
type: LocalParameter

849077
units: metaid_0000089
value: 0.00312
type: LocalParameter

850645
units: metaid_0000091
value: 1.0E7
type: LocalParameter

848182
units: metaid_0000090
value: 0.53
type: LocalParameter

847333
stoichiometry: 1.0
species: metaid_0000008
type: SpeciesReference

847249
stoichiometry: 1.0
species: metaid_0000008
type: SpeciesReference

848037
stoichiometry: 1.0
species: metaid_0000014
type: SpeciesReference

848121
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

850717
units: metaid_0000091
value: 1.0E7
type: LocalParameter

metaid_0000022
is: C00005
is: CHEBI:16474
boundary condition: false
name: NADPH
initial amount: NaN
type: Species
constant: false
initial concentration: 0.004
has only substance units: false
in compartment: metaid_0000003

850381
units: dimensionless
value: 1.0
type: LocalParameter

850200
units: metaid_0000089
value: 0.3055
type: LocalParameter

848426
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

850801
units: metaid_0000089
value: 2.0E-4
type: LocalParameter

850885
stoichiometry: 1.0
species: metaid_0000041
type: SpeciesReference

849318
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

849101
stoichiometry: 1.0
species: metaid_0000026
type: SpeciesReference

848824
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

848776
units: metaid_0000091
value: 1.68
type: LocalParameter

metaid_0000090
unit: 846848
unit: 846836
unit: 846824
name: mM_per_hour
type: SBMLUnitsDef

850513
units: metaid_0000089
value: 0.072
type: LocalParameter

metaid_0000021
is: C00256
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1.6803
initial amount: NaN
in compartment: metaid_0000003
name: Lactate
type: Species

850139
stoichiometry: 1.0
species: metaid_0000008
type: SpeciesReference

847721
units: metaid_0000089
value: 0.838
type: LocalParameter

847430
units: metaid_0000090
value: 239.0
type: LocalParameter

848280
units: metaid_0000089
value: 5.0
type: LocalParameter

848097
units: dimensionless
value: 100000.0
type: LocalParameter

metaid_0000080
kinetic law: 850561
product: 850549
product: 850537
reactant: 850525
fast: false
reversible: true
name: MgADP dissociation
type: Reaction

848932
stoichiometry: 1.0
species: metaid_0000026
type: SpeciesReference

metaid_0000070
kinetic law: 849512
name: Phosphoribulose epimerase
is: R01529
reversible: true
product: 849500
type: Reaction
reactant: 849488
is version of: http://identifiers.org/ec-code/5.1.3.1
is: REACT 1522
fast: false

850729
units: metaid_0000089
value: 1.667
type: LocalParameter

846994
units: dimensionless
value: 0.54
type: LocalParameter

metaid_0000010
in compartment: metaid_0000003
boundary condition: false
initial amount: NaN
is: C00118
is: CHEBI:29052
initial concentration: 0.0061
name: Glyceraldehyde 3-phosphate
constant: false
type: Species
has only substance units: false

847345
stoichiometry: 1.0
species: metaid_0000009
type: SpeciesReference

850393
stoichiometry: 1.0
species: metaid_0000046
type: SpeciesReference

851017
units: metaid_0000089
value: 2.0E-4
type: LocalParameter

848194
units: dimensionless
value: 100000.0
type: LocalParameter

metaid_0000020
is: CHEBI:15361
is: C00022
boundary condition: false
type: Species
has only substance units: false
initial amount: NaN
in compartment: metaid_0000003
initial concentration: 0.084
constant: false
name: Pyruvate

848025
units: metaid_0000089
value: 1.2
type: LocalParameter

848848
units: metaid_0000090
value: 1380.0
type: LocalParameter

850813
stoichiometry: 1.0
species: metaid_0000040
type: SpeciesReference

849993
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

850873
units: metaid_0000089
value: 1.0E-5
type: LocalParameter

metaid_0000081
kinetic law: 850633
product: 850621
product: 850609
reactant: 850597
fast: false
reversible: true
name: MgAMP dissociation
type: Reaction

849729
units: dimensionless
value: 1.05
type: LocalParameter

850501
units: metaid_0000091
value: 1.0E7
type: LocalParameter

850127
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

849717
units: metaid_0000090
value: 23.5
type: LocalParameter

848812
stoichiometry: 1.0
species: metaid_0000025
type: SpeciesReference

848788
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

848944
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

849560
units: metaid_0000089
value: 0.5
type: LocalParameter

metaid_0000082
kinetic law: 850705
product: 850693
product: 850681
reactant: 850669
fast: false
reversible: true
name: MgGri23P2 dissociation
type: Reaction

848402
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

849500
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

850825
stoichiometry: 1.0
species: metaid_0000039
type: SpeciesReference

846884
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

851005
units: metaid_0000091
value: 1.0E7
type: LocalParameter

metaid_0000012
is: CHEBI:35780
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.9992
initial amount: NaN
in compartment: metaid_0000003
name: Phosphate
type: Species

848013
units: metaid_0000089
value: 0.48
type: LocalParameter

metaid_0000039
name: Protein1
has only substance units: false
initial amount: NaN
type: Species
constant: false
in compartment: metaid_0000003
is version of: C00017
boundary condition: false
initial concentration: 0.0
is version of: CHEBI:36080

metaid_0000026
boundary condition: false
is: C01236
initial concentration: 0.025
is: CHEBI:16938
initial amount: NaN
name: Phospho-D-glucono-1,5-lactone
in compartment: metaid_0000003
has only substance units: false
type: Species
constant: false

846982
units: metaid_0000089
value: 6.9
type: LocalParameter

849246
units: dimensionless
value: 141.7
type: LocalParameter

847357
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

846836
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

847454
units: metaid_0000089
value: 0.1
type: LocalParameter

846799
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000011
initial concentration: 0.1492
is: C00111
initial amount: NaN
type: Species
constant: false
name: Dihydroxyacetone phosphate
has only substance units: false
boundary condition: false
is: CHEBI:16108
in compartment: metaid_0000003

848390
stoichiometry: 1.0
species: metaid_0000019
type: SpeciesReference

849415
units: metaid_0000089
value: 0.07
type: LocalParameter

849572
stoichiometry: 1.0
species: metaid_0000027
type: SpeciesReference

847879
units: metaid_0000089
value: 0.0083
type: LocalParameter

850261
units: dimensionless
value: 0.215
type: LocalParameter

848800
stoichiometry: 1.0
species: metaid_0000024
type: SpeciesReference

848752
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

metaid_0000025
type: Species
constant: false
name: ADP
initial amount: NaN
initial concentration: 0.25
boundary condition: false
is: C00008
in compartment: metaid_0000003
is: CHEBI:16761
has only substance units: false

850017
stoichiometry: 1.0
species: metaid_0000034
type: SpeciesReference

850224
units: metaid_0000089
value: 0.0548
type: LocalParameter

846824
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

850115
stoichiometry: 1.0
species: metaid_0000033
type: SpeciesReference

850537
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

846896
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

849306
stoichiometry: 1.0
species: metaid_0000028
type: SpeciesReference

848414
stoichiometry: 1.0
species: metaid_0000005
type: SpeciesReference

metaid_0000091
unit: 846860
name: hour_inverse
type: SBMLUnitsDef

848293
units: metaid_0000089
value: 1.0
type: LocalParameter

849909
units: metaid_0000089
value: 0.00823
type: LocalParameter

850837
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

850212
units: dimensionless
value: 0.122
type: LocalParameter

metaid_0000014
initial amount: NaN
initial concentration: 5.0E-4
is: CHEBI:16001
is: C00236
has only substance units: false
constant: false
in compartment: metaid_0000003
name: 1,3-Bisphospho-D-glycerate
type: Species
boundary condition: false

849258
units: metaid_0000089
value: 0.12
type: LocalParameter

847866
units: dimensionless
value: 1.92E-4
type: LocalParameter

846970
units: dimensionless
value: 1.0
type: LocalParameter

metaid_0000024
in compartment: metaid_0000003
name: AMP
has only substance units: false
initial amount: NaN
is: C00020
initial concentration: 0.0
type: Species
is: CHEBI:16027
constant: false
boundary condition: false

849403
units: metaid_0000089
value: 20.0
type: LocalParameter

849584
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

846848
exponent: -1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

847442
units: dimensionless
value: 100000.0
type: LocalParameter

metaid_0000092
unit: 846896
unit: 846884
unit: 846872
name: per_mM_hour
type: SBMLUnitsDef

846812
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

850861
units: metaid_0000091
value: 1.0E7
type: LocalParameter

metaid_0000013
boundary condition: false
name: NAD
initial amount: NaN
has only substance units: false
is: C00003
in compartment: metaid_0000003
is: CHEBI:15846
constant: false
type: Species
initial concentration: 0.0653

850525
stoichiometry: 1.0
species: metaid_0000007
type: SpeciesReference

850103
stoichiometry: 1.0
species: metaid_0000030
type: SpeciesReference

848000
units: dimensionless
value: 1455.0
type: LocalParameter

metaid_0000023
type: Species
constant: false
initial concentration: 0.0
name: NADP
boundary condition: false
in compartment: metaid_0000003
is: CHEBI:18009
has only substance units: false
is: C00006
initial amount: NaN

850285
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

metaid_0000055
product: 847782
is: R01061
product: 847794
reactant: 847770
reactant: 847757
reactant: 847745
fast: false
reversible: true
is: REACT 1847
is version of: http://identifiers.org/ec-code/1.2.1.12
type: Reaction
name: Glyceraldehyde 3-phosphate dehydrogenase
kinetic law: 847806

848656
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

metaid_0000087
unit: 846775
name: millimole
type: SBMLUnitsDef

metaid_0000035
has only substance units: false
name: ATP
boundary condition: false
is: CHEBI:15422
type: Species
constant: false
is: C00002
initial concentration: 0.25
in compartment: metaid_0000003
initial amount: NaN

847200
units: metaid_0000089
value: 0.0045
type: LocalParameter

metaid_0000077
kinetic law: 850357
product: 850345
reactant: 850333
is version of: GO:0009935
fast: false
reversible: true
name: Lactate exchange
type: Reaction

847297
units: metaid_0000089
value: 0.182
type: LocalParameter

metaid_0000016
is: CHEBI:17794
name: 3-Phospho-D-glycerate
is: C00197
boundary condition: false
initial concentration: 0.0658
has only substance units: false
constant: false
type: Species
initial amount: NaN
in compartment: metaid_0000003

metaid_0000049
kinetic law: 846933
product: 846920
reactant: 846908
is: REACT 2092
is version of: GO:0046323
fast: false
reversible: true
name: Glucose transport
type: Reaction

metaid_0000069
kinetic law: 849463
product: 849451
reactant: 849439
is: REACT 2037
is version of: http://identifiers.org/ec-code/1.8.1.7
fast: false
reversible: true
name: Glutathione oxidation
type: Reaction

846775
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

848559
stoichiometry: 1.0
species: metaid_0000015
type: SpeciesReference

847550
stoichiometry: 1.0
species: metaid_0000011
type: SpeciesReference

850067
units: dimensionless
value: 100000.0
type: LocalParameter

850333
stoichiometry: 1.0
species: metaid_0000045
type: SpeciesReference

847854
units: metaid_0000089
value: 3.9
type: LocalParameter

metaid_0000088
unit: 846787
name: hour
type: SBMLUnitsDef

metaid_0000036
initial amount: NaN
in compartment: metaid_0000003
boundary condition: false
has only substance units: false
type: Species
constant: false
is: C00305
name: Mg
initial concentration: 0.8
is: CHEBI:25107

metaid_0000029
boundary condition: false
is: C00051
is: CHEBI:16856
in compartment: metaid_0000003
type: Species
constant: false
name: Reduced Glutathione
initial amount: NaN
has only substance units: false
initial concentration: 3.1136

metaid_0000015
in compartment: metaid_0000003
name: NADH
is: CHEBI:16908
has only substance units: false
is: C00004
initial concentration: 2.0E-4
initial amount: NaN
constant: false
boundary condition: false
type: Species

metaid_0000009
type: Species
is: CHEBI:28013
initial concentration: 0.0097
is: C05378
in compartment: metaid_0000003
constant: false
boundary condition: false
name: Fructose 1,6-phosphate
initial amount: NaN
has only substance units: false

850933
units: metaid_0000091
value: 1.0E7
type: LocalParameter

metaid_0000078
kinetic law: 850417
product: 850405
reactant: 850393
is version of: GO:0009935
fast: false
reversible: true
name: Pyruvate exchange
type: Reaction

847538
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

849524
units: metaid_0000090
value: 4634.0
type: LocalParameter

metaid_0000056
is version of: http://identifiers.org/ec-code/2.7.2.3
reactant: 847916
kinetic law: 847952
reactant: 847904
product: 847940
reversible: true
product: 847928
is: R01512
is: REACT 1186
name: Phosphoglycerate kinase
type: Reaction
fast: false

850005
stoichiometry: 1.0
species: metaid_0000031
type: SpeciesReference

848740
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

metaid_0000037
in compartment: metaid_0000003
name: MgGri23P2
has only substance units: false
constant: false
boundary condition: false
type: Species
has part: C00305
initial concentration: 0.5
initial amount: NaN
has part: C01159
has part: CHEBI:25107
has part: CHEBI:17720

847212
units: metaid_0000089
value: 2.7
type: LocalParameter

metaid_0000028
initial concentration: 4.0E-4
is: CHEBI:17858
name: Oxidized Glutathione
type: Species
boundary condition: false
has only substance units: false
constant: false
initial amount: NaN
in compartment: metaid_0000003
is: C00127

847757
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

847285
units: dimensionless
value: 0.3925
type: LocalParameter

850309
units: metaid_0000091
value: 100.0
type: LocalParameter

848644
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

850273
stoichiometry: 1.0
species: metaid_0000048
type: SpeciesReference

metaid_0000018
initial concentration: 0.0084
in compartment: metaid_0000003
constant: false
name: 2-Phospho-D-glycerate
type: Species
boundary condition: false
initial amount: NaN
has only substance units: false
is: C00631
is: CHEBI:17835

metaid_0000047
constant: false
name: Glucose outside
is: C00293
initial amount: NaN
in compartment: metaid_0000003
is: CHEBI:17234
boundary condition: true
has only substance units: false
initial concentration: 5.0
type: Species

metaid_0000075
is: REACT 1811
is version of: http://identifiers.org/ec-code/2.2.1.1
product: 850127
name: Transketolase 2
is: R01830
type: Reaction
kinetic law: 850151
product: 850139
fast: false
reactant: 850103
reactant: 850115
reversible: true

849041
units: metaid_0000089
value: 0.00367
type: LocalParameter

metaid_0000067
has part: REACT 611
reactant: 849114
has part: R01528
type: Reaction
is version of: http://identifiers.org/ec-code/1.1.1.44
modifier: 849186
modifier: 849150
has part: R02035
has part: REACT 2072
modifier: 849174
name: Phosphogluconate dehydrogenase
kinetic law: 849198
product: 849126
reversible: true
fast: false
reactant: 849101
product: 849138
modifier: 849162

850321
units: dimensionless
value: 1.0
type: LocalParameter

846787
exponent: 1.0
scale: 0
multipler: 3600.0
kind: SECOND
type: SBMLUnit

metaid_0000008
is: C05345
name: Fructose 6-phosphate
boundary condition: false
in compartment: metaid_0000003
type: Species
initial concentration: 0.0153
is: CHEBI:16084
initial amount: NaN
constant: false
has only substance units: false

metaid_0000057
reversible: true
fast: false
kinetic law: 848073
name: Bisphosphoglycerate mutase
reactant: 848037
product: 848049
is: R01662
type: Reaction
is version of: http://identifiers.org/ec-code/5.4.2.4
modifier: 848061

metaid_0000089
unit: 846812
unit: 846799
name: mM
type: SBMLUnitsDef

850055
units: metaid_0000090
value: 1.1
type: LocalParameter

metaid_0000027
initial amount: NaN
boundary condition: false
in compartment: metaid_0000003
is: C00199
name: Ribulose 5-phosphate
is: CHEBI:17363
type: Species
has only substance units: false
constant: false
initial concentration: 0.0047

metaid_0000038
constant: false
in compartment: metaid_0000003
has part: C00006
type: Species
has only substance units: false
has part: C00017
name: Protein1 bound NADP
initial concentration: 0.0
has part: CHEBI:36080
has part: CHEBI:18009
initial amount: NaN
boundary condition: false

metaid_0000017
constant: false
has only substance units: false
type: Species
is: C01159
initial amount: NaN
name: 2,3-Bisphospho-D-glycerate
boundary condition: false
is: CHEBI:17720
initial concentration: 2.0601
in compartment: metaid_0000003

847842
units: metaid_0000089
value: 0.005
type: LocalParameter

metaid_0000048
is: CHEBI:35780
constant: false
boundary condition: true
has only substance units: false
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000003
name: Phosphate external
type: Species

metaid_0000076
kinetic law: 850297
product: 850285
reactant: 850273
is version of: GO:0009935
fast: false
reversible: true
name: Phosphate exchange
type: Reaction

847490
units: metaid_0000089
value: 0.01
type: LocalParameter

metaid_0000068
is: REACT 2220
kinetic law: 849354
is version of: http://identifiers.org/ec-code/1.8.1.7
reversible: true
is: R00094
name: Glutathione reductase
product: 849342
reactant: 849306
type: Reaction
fast: false
product: 849330
reactant: 849318

850681
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

849861
stoichiometry: 1.0
species: metaid_0000008
type: SpeciesReference

metaid_0000058
product: 848145
kinetic law: 848170
reversible: true
modifier: 848158
product: 848133
type: Reaction
reactant: 848121
name: Bisphosphoglycerate phosphatase
is: R01516
is version of: http://identifiers.org/ec-code/3.1.3.13
fast: false

metaid_0000007
boundary condition: false
has part: CHEBI:25107
initial concentration: 0.1
initial amount: NaN
constant: false
has only substance units: false
has part: C00305
in compartment: metaid_0000003
type: Species
has part: CHEBI:16761
name: MgADP
has part: C00008

850945
units: metaid_0000089
value: 1.0E-5
type: LocalParameter

849488
stoichiometry: 1.0
species: metaid_0000027
type: SpeciesReference

847940
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

metaid_0000045
is: C00256
constant: false
boundary condition: true
has only substance units: false
initial concentration: 1.68
initial amount: NaN
in compartment: metaid_0000003
name: External Lactate
type: Species

848535
units: metaid_0000089
value: 3.39
type: LocalParameter

847574
units: metaid_0000090
value: 98.91000366
type: LocalParameter

metaid_0000073
reversible: true
fast: false
is version of: http://identifiers.org/ec-code/2.2.1.2
product: 849861
is: R01827
type: Reaction
reactant: 849837
name: Transaldolase
is: REACT 479
reactant: 849825
kinetic law: 849873
product: 849849

metaid_0000083
kinetic law: 850777
product: 850765
product: 850753
reactant: 850741
fast: false
reversible: true
name: P1NADP dissociation
type: Reaction

848632
units: dimensionless
value: 9090.0
type: LocalParameter

metaid_0000031
name: Ribose 5-phosphate
is: C00117
is: CHEBI:17797
initial amount: NaN
initial concentration: 0.014
in compartment: metaid_0000003
has only substance units: false
type: Species
constant: false
boundary condition: false

metaid_0000059
reversible: true
fast: false
product: 848230
type: Reaction
reactant: 848218
name: Phosphoglycerate mutase
kinetic law: 848243
is version of: http://identifiers.org/ec-code/5.4.2.1
is: REACT 576
is: R01518

848499
units: metaid_0000089
value: 0.225
type: LocalParameter

850405
stoichiometry: 1.0
species: metaid_0000020
type: SpeciesReference

849379
units: metaid_0000089
value: 0.0652
type: LocalParameter

metaid_0000006
initial amount: NaN
boundary condition: false
constant: false
initial concentration: 0.0394
is: CHEBI:17665
in compartment: metaid_0000003
is: C00668
type: Species
has only substance units: false
name: Glucose 6-phosphate

847224
units: metaid_0000089
value: 3.44
type: LocalParameter

849053
units: dimensionless
value: 2000.0
type: LocalParameter

847745
stoichiometry: 1.0
species: metaid_0000010
type: SpeciesReference

848680
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000074
kinetic law: 850043
is: R01049
fast: false
product: 850030
name: Phosphoribosylpyrophosphate synthetase
type: Reaction
reactant: 850005
reactant: 849993
is version of: http://identifiers.org/ec-code/2.7.6.1
product: 850017
is: REACT 2023
reversible: true

metaid_0000046
in compartment: metaid_0000003
boundary condition: true
is: CHEBI:32816
initial amount: NaN
has only substance units: false
name: External Pyruvate
initial concentration: 0.084
type: Species
is: C00022
constant: false

metaid_0000019
is: C00074
initial amount: NaN
is: CHEBI:18021
has only substance units: false
name: Phosphoenolpyruvate
boundary condition: false
constant: false
initial concentration: 0.0109
in compartment: metaid_0000003
type: Species

850957
stoichiometry: 1.0
species: metaid_0000043
type: SpeciesReference

847514
units: metaid_0000089
value: 0.033
type: LocalParameter

849548
units: metaid_0000089
value: 0.19
type: LocalParameter

849476
units: metaid_0000091
value: 0.03
type: LocalParameter

850693
stoichiometry: 1.0
species: metaid_0000017
type: SpeciesReference

metaid_0000084
kinetic law: 850849
product: 850837
product: 850825
reactant: 850813
is version of: GO:0006740
fast: false
reversible: true
name: P1NADPH dissociation
type: Reaction

849897
units: dimensionless
value: 1.05
type: LocalParameter

847891
units: metaid_0000089
value: 0.0035
type: LocalParameter

850609
stoichiometry: 1.0
species: metaid_0000036
type: SpeciesReference

metaid_0000032
is: C05382
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0154
initial amount: NaN
in compartment: metaid_0000003
name: Sedoheptulose 7-phosphate
type: Species

metaid_0000005
type: Species
has only substance units: false
has part: C00305
initial amount: NaN
constant: false
has part: CHEBI:15422
in compartment: metaid_0000003
initial concentration: 1.4
boundary condition: false
has part: CHEBI:25107
name: MgATP
has part: C00002

847830
units: metaid_0000089
value: 0.05
type: LocalParameter

848145
stoichiometry: 1.0
species: metaid_0000012
type: SpeciesReference

metaid_0000071
reversible: true
is: R01056
name: Ribose phosphate isomerase
fast: false
product: 849584
is: http://identifiers.org/ec-code/5.3.1.6
type: Reaction
is: REACT 2033
kinetic law: 849596
reactant: 849572

848920
stoichiometry: 1.0
species: metaid_0000023
type: SpeciesReference

metaid_0000085
kinetic law: 850921
product: 850909
product: 850897
reactant: 850885
fast: false
reversible: true
name: P2NADP dissociation
type: Reaction

848547
units: metaid_0000089
value: 0.005
type: LocalParameter

850079
units: metaid_0000089
value: 0.03
type: LocalParameter

847586
units: metaid_0000089
value: 0.0071
type: LocalParameter

848085
units: metaid_0000091
value: 76000.0
type: LocalParameter

metaid_0000033
initial amount: NaN
initial concentration: 0.0063
is: C00279
is: CHEBI:16897
type: Species
constant: false
in compartment: metaid_0000003
has only substance units: false
name: Erythrose 4-phosphate
boundary condition: false

metaid_0000004
has only substance units: false
initial amount: NaN
type: Species
is: C00293
boundary condition: false
initial concentration: 4.5663
in compartment: metaid_0000003
constant: false
name: Glucose in
is: CHEBI:17234

847733
units: metaid_0000089
value: 0.428
type: LocalParameter

850981
stoichiometry: 1.0
species: metaid_0000022
type: SpeciesReference

848620
units: metaid_0000092
value: 2800000.0
type: LocalParameter

metaid_0000043
constant: false
has only substance units: false
has part: C00017
initial concentration: 0.024
boundary condition: false
has part: CHEBI:36080
name: Protein2 bound NADPH
has part: CHEBI:16474
initial amount: NaN
has part: C00005
type: Species
in compartment: metaid_0000003

848487
units: dimensionless
value: 13790.0
type: LocalParameter

849065
units: metaid_0000089
value: 0.749
type: LocalParameter

847236
stoichiometry: 1.0
species: metaid_0000006
type: SpeciesReference

850897
stoichiometry: 1.0
species: metaid_0000042
type: SpeciesReference

metaid_0000072
is version of: http://identifiers.org/ec-code/2.2.1.1
reactant: 849657
product: 849693
product: 849681
reactant: 849669
kinetic law: 849705
name: Transketolase 1
reversible: true
is: R01641
type: Reaction
fast: false
is: REACT 1629

850969
stoichiometry: 1.0
species: metaid_0000042
type: SpeciesReference

metaid_0000034
type: Species
boundary condition: false
in compartment: metaid_0000003
initial concentration: 0.0
initial amount: NaN
name: MgAMP
has only substance units: false
has part: C00020
has part: C00305
has part: CHEBI:16027
constant: false
has part: CHEBI:25107

metaid_0000086
kinetic law: 850993
product: 850981
product: 850969
reactant: 850957
is version of: GO:0006735
fast: false
reversible: true
name: P2NADPH dissociation
type: Reaction

849885
units: metaid_0000090
value: 27.2
type: LocalParameter

849536
units: dimensionless
value: 2.7
type: LocalParameter

847526
stoichiometry: 1.0
species: metaid_0000009
type: SpeciesReference

849451
stoichiometry: 1.0
species: metaid_0000028
type: SpeciesReference

848133
stoichiometry: 1.0
species: metaid_0000016
type: SpeciesReference

metaid_0000003
is: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
name: cytoplasm
type: Compartment

848342
units: metaid_0000090
value: 1500.0
type: LocalParameter

850345
stoichiometry: 1.0
species: metaid_0000021
type: SpeciesReference

metaid_0000044
is: CHEBI:17111
initial amount: NaN
type: Species
in compartment: metaid_0000003
boundary condition: true
initial concentration: 1.0
is: C00119
name: PRPP
constant: false
has only substance units: false

orgname: Stellenbosh University

ORG:
  orgname: California Institute of Technology
n:
  given: Harish
  family: Dharuri

n:
  given: Jacky L
  family: Snoep

W3 CDTF: Wed May 16 11:20:02 BST 2012