326433
exponent: 3.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000169
unit: 326361
unit: 326349
name: volume per time
type: SBMLUnitsDef

metaid_0000155
constant: true
units: metaid_0000165
value: 6158.0
type: Parameter

326843
stoichiometry: 1.0
species: metaid_0000094
type: SpeciesReference

326325
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

326530
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000135
kinetic law: 326602
reactant: 326590
has part: GO:0005524
has part: GO:0005388
is: http://identifiers.org/ec-code/3.6.3.8
fast: false
reversible: false
type: Reaction

metaid_0000149
kinetic law: 326939
reactant: 326927
is: GO:0005388
is: http://identifiers.org/ec-code/3.6.3.8
fast: false
reversible: false
type: Reaction

metaid_1000168
unit: 326301
unit: 326289
name: amount per time
type: SBMLUnitsDef

metaid_0000009
constant: true
units: metaid_0000163
value: 132400.0
type: Parameter

326795
stoichiometry: 1.0
species: metaid_0000094
type: SpeciesReference

metaid_0000020
constant: true
units: metaid_0000161
value: 0.0
type: Parameter

metaid_0000168
unit: 326337
unit: 326325
unit: 326313
name: concentration per time
type: SBMLUnitsDef

metaid_0000154
constant: false
units: metaid_0000161
value: -60.9
type: Parameter

metaid_0000134
kinetic law: 326578
product: 326566
is version of: GO:0005432
fast: false
reversible: false
type: Reaction

metaid_0000148
kinetic law: 326915
reactant: 326903
is: GO:0005391
is: http://identifiers.org/ec-code/3.6.3.9
fast: false
reversible: false
type: Reaction

326253
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000040
constant: true
units: metaid_0000163
value: 150400.0
type: Parameter

metaid_0000029
constant: true
units: metaid_0000172
value: 1.5E-8
type: Parameter

326445
exponent: -2.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000167
unit: 326277
unit: 326265
name: Conductance coefficient
type: SBMLUnitsDef

metaid_0000069
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

metaid_0000049
constant: true
units: metaid_0000163
value: 17.0
type: Parameter

metaid_0000147
kinetic law: 326891
modifier: 326879
product: 326867
is: GO:0006754
fast: false
reversible: false
type: Reaction

metaid_0000137
kinetic law: 326674
product: 326662
reactant: 326650
has part: GO:0005220
has part: GO:0007204
fast: false
reversible: false
type: Reaction

326337
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000166
unit: 326253
name: Time inverse
type: SBMLUnitsDef

W3 CDTF: Thu Jul 05 17:49:00 BST 2012

326927
stoichiometry: 1.0
species: metaid_0000095
type: SpeciesReference

326265
exponent: 1.0
scale: -12
multipler: 1.0
kind: SIEMENS
type: SBMLUnit

metaid_0000146
kinetic law: 326855
product: 326843
is version of: GO:0005227
fast: false
reversible: false
type: Reaction

metaid_0000136
has part: GO:0005388
reversible: false
product: 326626
type: Reaction
has part: GO:0005524
is: http://identifiers.org/ec-code/3.6.3.8
reactant: 326614
kinetic law: 326638
fast: false

326349
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

326193
exponent: 1.0
scale: -15
multipler: 1.0
kind: AMPERE
type: SBMLUnit

326686
stoichiometry: 1.0
species: metaid_0000091
type: SpeciesReference

metaid_0000159
unit: 326157
name: Micromole
type: SBMLUnitsDef

metaid_0000006
constant: true
units: metaid_0000163
value: 2600.0
type: Parameter

metaid_0000185
constant: true
units: metaid_0000166
value: 5.0E-5
name: Rate constant of ATP consumption
type: Parameter

metaid_0000071
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

326590
stoichiometry: 1.0
species: metaid_0000091
type: SpeciesReference

metaid_0000145
kinetic law: 326831
product: 326819
is version of: GO:0005248
fast: false
reversible: false
type: Reaction

metaid_0000043
constant: true
units: metaid_0000166
value: 0.172
type: Parameter

metaid_0000047
constant: true
units: metaid_0000163
value: 0.1
type: Parameter

326747
stoichiometry: 1.0
species: metaid_0000093
type: SpeciesReference

metaid_0000057
constant: true
units: metaid_0000161
value: -75.0
type: Parameter

326494
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000081
constant: true
units: metaid_0000163
value: 0.5
type: Parameter

metaid_0000019
constant: false
units: metaid_0000161
value: 0.0
type: Parameter

metaid_0000005
constant: true
units: metaid_0000161
value: 26.73
type: Parameter

metaid_0000184
constant: true
units: metaid_0000170
value: 5.0E-5
name: Ca dependent ATP consumption
type: Parameter

metaid_0000158
is: C00008
type: Species
name: Cytosolic ADP
has only substance units: false
boundary condition: false
initial concentration: 3067.9
in compartment: metaid_0000088
is: CHEBI:16761
constant: false
initial amount: NaN

metaid_0000070
constant: true
units: metaid_0000164
value: 1200.0
type: Parameter

326771
stoichiometry: 1.0
species: metaid_0000094
type: SpeciesReference

metaid_0000044
constant: true
units: metaid_0000166
value: 11.5
type: Parameter

metaid_0000144
kinetic law: 326807
reactant: 326795
is: GO:0005391
is: http://identifiers.org/ec-code/3.6.3.9
fast: false
reversible: false
type: Reaction

metaid_0000058
constant: true
units: metaid_0000161
value: 65.0
type: Parameter

metaid_0000030
constant: false
value: 0.0
type: Parameter

metaid_0000048
constant: false
units: dimensionless
value: 0.0
type: Parameter

metaid_0000080
constant: false
units: metaid_0000168
value: 0.105
type: Parameter

metaid_0000018
constant: true
units: metaid_0000163
value: 200.0
type: Parameter

metaid_0000084
constant: true
units: metaid_0000163
value: 3.2
type: Parameter

metaid_0000183
constant: true
units: metaid_0000166
value: 3.7E-4
name: ATP production rate constant
type: Parameter

metaid_0000008
constant: true
units: metaid_0000163
value: 8000.0
type: Parameter

metaid_0000045
constant: true
units: metaid_0000166
value: 100.0
type: Parameter

metaid_0000143
kinetic law: 326783
reactant: 326771
is: GO:0005432
fast: false
reversible: false
type: Reaction

metaid_0000041
constant: false
value: 0.0
type: Parameter

metaid_0000059
constant: true
units: metaid_0000161
value: 20.0
type: Parameter

metaid_0000182
constant: true
units: metaid_0000166
value: 4.0E-5
name: IP3 degradation rate constant
type: Parameter

metaid_0000083
constant: true
units: metaid_0000163
value: 0.077
type: Parameter

metaid_0000133
kinetic law: 326554
product: 326542
is version of: GO:0005245
fast: false
reversible: false
type: Reaction

326421
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000031
constant: false
value: 0.0
type: Parameter

326409
exponent: -3.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

326241
exponent: 1.0
scale: -15
multipler: 1.0
kind: FARAD
type: SBMLUnit

metaid_0000017
constant: true
units: metaid_0000167
value: 0.7
type: Parameter

metaid_0000007
constant: false
units: metaid_0000161
value: 0.0
type: Parameter

metaid_0000046
constant: false
units: dimensionless
value: 0.0
type: Parameter

metaid_0000042
constant: true
units: metaid_0000166
value: 10.0
type: Parameter

metaid_0000181
constant: true
units: metaid_0000163
value: 0.4
name: half activation cytosolic Ca
type: Parameter

metaid_0000142
kinetic law: 326759
reactant: 326747
fast: false
reversible: false
type: Reaction

metaid_0000082
constant: false
units: dimensionless
value: 0.0
type: Parameter

metaid_0000032
constant: true
units: metaid_0000170
value: 1.0E-4
type: Parameter

326903
stoichiometry: 1.0
species: metaid_0000095
type: SpeciesReference

metaid_0000022
constant: false
value: 0.0
type: Parameter

326481
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000094
initial amount: NaN
has only substance units: false
type: Species
initial concentration: 9858.0
in compartment: metaid_0000088
boundary condition: false
is: CHEBI:29101
constant: false
is: C01330
name: Cytosolic Sodium

metaid_0000066
constant: true
units: metaid_0000164
value: 271.0
type: Parameter

326385
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

326975
stoichiometry: 1.0
species: metaid_0000095
type: SpeciesReference

metaid_0000056
constant: true
units: metaid_0000160
value: 20.0
type: Parameter

metaid_0000171
unit: 326433
unit: 326421
unit: 326409
name: per concentration cubed per time
type: SBMLUnitsDef

metaid_0000180
constant: true
units: metaid_0000168
value: 3.0E-4
name: IP3 production rate constant
type: Parameter

metaid_0000036
constant: true
units: metaid_0000170
value: 2.0E-4
type: Parameter

metaid_0000152
kinetic law: 327023
reactant: 327011
is: GO:0006200
fast: false
reversible: false
type: Reaction

326518
exponent: 1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000172
unit: 326469
unit: 326457
unit: 326445
name: per Concentration square per time
type: SBMLUnitsDef

metaid_0000076
constant: true
units: metaid_0000164
value: 130.0
type: Parameter

metaid_0000016
constant: false
value: 0.0
type: Parameter

326710
stoichiometry: 1.0
species: metaid_0000093
type: SpeciesReference

metaid_0000086
constant: true
units: metaid_0000169
value: 1.0E-16
type: Parameter

metaid_0000095
boundary condition: false
is: C00002
initial amount: NaN
name: Cytosolic ATP
type: Species
in compartment: metaid_0000088
has only substance units: false
constant: false
initial concentration: 932.1
is: CHEBI:15422

metaid_0000065
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

metaid_0000021
constant: false
units: dimensionless
value: 0.0
type: Parameter

326819
stoichiometry: 1.0
species: metaid_0000094
type: SpeciesReference

BIOMD0000000059
parameter: metaid_0000054
compartment: metaid_0000175
reaction: metaid_0000145
rule: metaid_0000101
parameter: metaid_0000038
parameter: metaid_0000018
parameter: metaid_0000068
rule: metaid_0000128
rule: metaid_0000097
parameter: metaid_0000154
parameter: metaid_0000185
parameter: metaid_0000085
parameter: metaid_0000182
rule: metaid_0000156
reaction: metaid_0000141
parameter: metaid_0000031
rule: metaid_0000110
parameter: metaid_0000084
parameter: metaid_0000033
parameter: metaid_0000064
parameter: metaid_0000081
parameter: metaid_0000061
units def: metaid_0000164
rule: metaid_0000129
parameter: metaid_0000049
parameter: metaid_0000012
species: metaid_0000092
parameter: metaid_0000077
units def: metaid_0000168
parameter: metaid_0000179
has part: GO:0050848
reaction: metaid_0000133
reaction: metaid_0000150
parameter: metaid_0000026
parameter: metaid_0000056
parameter: metaid_0000025
parameter: metaid_0000006
rule: metaid_0000119
rule: metaid_0000106
parameter: metaid_0000059
parameter: metaid_0000058
units def: metaid_0000171
parameter: metaid_0000073
time units: metaid_0000160
rule: metaid_0000122
reaction: metaid_0000147
reaction: metaid_0000146
parameter: metaid_0000021
parameter: metaid_0000052
parameter: metaid_0000087
units def: metaid_0000159
has part: GO:0050796
rule: metaid_0000107
parameter: metaid_0000035
substance units: metaid_0000159
parameter: metaid_0000083
reaction: metaid_0000142
units def: metaid_0000162
rule: metaid_0000131
parameter: metaid_0000065
rule: metaid_0000123
compartment: metaid_0000088
species: metaid_0000094
parameter: metaid_0000013
units def: metaid_0000166
parameter: metaid_0000079
parameter: metaid_0000029
rule: metaid_0000104
rule: metaid_0000117
parameter: metaid_0000046
units def: metaid_0000169
parameter: metaid_0000028
reaction: metaid_0000152
parameter: metaid_0000008
parameter: metaid_0000042
parameter: metaid_0000177
reaction: metaid_0000134
rule: metaid_0000120
parameter: metaid_0000075
units def: metaid_0000172

metaid_0000055
constant: false
units: metaid_0000160
value: 0.0
type: Parameter

metaid_0000153
constant: false
value: 0.00123
type: Parameter

metaid_0000035
constant: false
value: 0.0
type: Parameter

326313
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

326469
exponent: 2.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000075
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

metaid_0000173
unit: 326494
unit: 326481
name: per concentration
type: SBMLUnitsDef

326662
stoichiometry: 0.01
species: metaid_0000091
type: SpeciesReference

327011
stoichiometry: 1.0
species: metaid_0000095
type: SpeciesReference

metaid_0000085
constant: false
units: metaid_1000168
value: 0.0
type: Parameter

metaid_0000015
constant: true
units: metaid_0000161
value: 9.5
type: Parameter

metaid_0000068
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

metaid_0000092
in compartment: metaid_0000175
constant: false
has only substance units: false
initial amount: NaN
name: ER Calcium
is: C00076
type: Species
is: CHEBI:29108
boundary condition: false
initial concentration: 22.8

metaid_0000024
constant: false
value: 0.0
type: Parameter

326397
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000150
kinetic law: 326963
reactant: 326951
is: GO:0005388
is: http://identifiers.org/ec-code/3.6.3.8
fast: false
reversible: false
type: Reaction

metaid_0000034
constant: true
units: metaid_0000171
value: 1.72E-17
type: Parameter

metaid_0000054
constant: true
units: metaid_0000161
value: 7.0
type: Parameter

metaid_0000074
constant: true
units: metaid_0000164
value: 3000.0
type: Parameter

metaid_0000004
constant: false
units: metaid_0000161
value: 0.0
type: Parameter

metaid_0000014
constant: true
units: metaid_0000161
value: -19.0
type: Parameter

metaid_0000088
is: GO:0005737
constant: true
size: 7.64E-13
spatial dimensions: 3.0
name: cytoplasm
type: Compartment

326506
exponent: 1.0
scale: -15
multipler: 1.0
kind: AMPERE
type: SBMLUnit

metaid_0000160
unit: 326169
name: milliseconds
type: SBMLUnitsDef

326205
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000067
constant: true
units: metaid_0000163
value: 0.75
type: Parameter

metaid_0000093
in compartment: metaid_0000088
constant: false
initial concentration: 0.33
initial amount: NaN
has only substance units: false
type: Species
boundary condition: false
is: C01245
name: Cytosolic IP3
is: CHEBI:16595

metaid_0000141
kinetic law: 326735
modifier: 326723
product: 326710
is: GO:0004435
is: http://identifiers.org/ec-code/3.1.4.11
fast: false
reversible: false
type: Reaction

metaid_0000023
constant: true
units: metaid_0000170
value: 0.002
type: Parameter

metaid_0000053
constant: true
units: metaid_0000161
value: -14.0
type: Parameter

326301
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000033
constant: false
value: 0.0
type: Parameter

metaid_0000151
kinetic law: 326999
modifier: 326987
reactant: 326975
is: GO:0030899
fast: false
reversible: false
type: Reaction

metaid_0000072
constant: true
units: metaid_0000162
value: 600.0
type: Parameter

metaid_0000170
unit: 326397
unit: 326385
unit: 326373
name: per concentration per time
type: SBMLUnitsDef

326650
stoichiometry: 0.03
species: metaid_0000092
type: SpeciesReference

metaid_0000013
constant: false
value: 0.0
type: Parameter

326181
exponent: 1.0
scale: -3
multipler: 1.0
kind: VOLT
type: SBMLUnit

metaid_0000073
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

326566
stoichiometry: 1.0
species: metaid_0000091
type: SpeciesReference

326157
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000087
constant: true
units: metaid_0000169
value: 1.2E-15
type: Parameter

metaid_0000161
unit: 326181
name: Voltage
type: SBMLUnitsDef

326457
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

326614
stoichiometry: 0.01
species: metaid_0000091
type: SpeciesReference

326289
exponent: 1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000052
constant: false
units: dimensionless
value: 0.0
type: Parameter

metaid_0000026
constant: false
value: 0.0
type: Parameter

metaid_0000062
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

metaid_0000162
unit: 326193
name: Current
type: SBMLUnitsDef

326361
exponent: -1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000061
constant: true
units: metaid_0000164
value: 770.0
type: Parameter

metaid_0000176
constant: true
units: dimensionless
value: 0.01
type: Parameter

326951
stoichiometry: 1.0
species: metaid_0000095
type: SpeciesReference

metaid_0000012
constant: false
units: metaid_0000161
value: 0.0
type: Parameter

metaid_0000138
kinetic law: 326698
reactant: 326686
is: GO:0051208
fast: false
reversible: false
type: Reaction

metaid_0000051
constant: true
units: metaid_0000163
value: 1.0
type: Parameter

326867
stoichiometry: 1.0
species: metaid_0000095
type: SpeciesReference

metaid_0000025
constant: true
units: metaid_0000166
value: 0.03
type: Parameter

metaid_0000039
constant: true
units: metaid_0000170
value: 6.0E-7
type: Parameter

metaid_0000091
type: Species
name: Cytosolic Calcium
is: CHEBI:29108
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.085
initial amount: NaN
in compartment: metaid_0000088
is: C00076

326169
exponent: 1.0
scale: -3
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000163
unit: 326217
unit: 326205
name: Concentration
type: SBMLUnitsDef

metaid_0000060
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

metaid_0000079
constant: false
units: metaid_0000168
value: 0.0
type: Parameter

326217
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

metaid_0000050
constant: true
units: metaid_0000163
value: 26.0
type: Parameter

metaid_0000177
constant: true
units: metaid_0000174
value: 9.6485E16
name: Faraday's constant
type: Parameter

metaid_0000011
constant: true
units: metaid_0000163
value: 140000.0
type: Parameter

metaid_0000028
constant: false
value: 0.0
type: Parameter

326626
stoichiometry: 0.03
species: metaid_0000092
type: SpeciesReference

326277
exponent: -1.0
scale: -3
multipler: 1.0
kind: VOLT
type: SBMLUnit

metaid_0000038
constant: false
value: 0.0
type: Parameter

metaid_0000064
constant: true
units: metaid_0000163
value: 0.1
type: Parameter

metaid_0000164
unit: 326229
name: Conductance
type: SBMLUnitsDef

metaid_0000174
unit: 326530
unit: 326518
unit: 326506
name: Faraday constant
type: SBMLUnitsDef

metaid_0000178
constant: true
units: metaid_0000166
value: 1.0E-4
type: Parameter

metaid_0000078
constant: true
units: metaid_0000164
value: 24000.0
type: Parameter

326373
exponent: -1.0
scale: -6
multipler: 1.0
kind: MOLE
type: SBMLUnit

metaid_0000010
constant: false
units: metaid_0000161
value: 0.0
type: Parameter

metaid_0000027
constant: true
units: metaid_0000171
value: 2.5E-10
type: Parameter

326542
stoichiometry: 1.0
species: metaid_0000091
type: SpeciesReference

metaid_0000063
constant: true
units: metaid_0000162
value: 2000.0
type: Parameter

metaid_0000037
constant: true
units: metaid_0000163
value: 4950.0
type: Parameter

metaid_0000165
unit: 326241
name: Capacitance
type: SBMLUnitsDef

326229
exponent: 1.0
scale: -12
multipler: 1.0
kind: SIEMENS
type: SBMLUnit

metaid_0000179
constant: true
units: dimensionless
value: 0.03
type: Parameter

metaid_0000175
is: GO:0005783
constant: true
size: 2.8E-13
spatial dimensions: 3.0
name: endoplasmic reticulum
type: Compartment

metaid_0000077
constant: false
units: metaid_0000162
value: 0.0
type: Parameter

given: Harish
family: Dharuri

orgname: California Institute of Technology

W3 CDTF: Tue Jun 20 14:12:19 BST 2006