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is: R04560
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is version of: http://identifiers.org/ec-code/2.1.2.3

616451
value: 0.063
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is: CHEBI:18406
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617244
value: 0.03
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name: 10-formyl-dihydrofolate
is: CHEBI:15634
initial concentration: 3.32E-4
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613843
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scale: 0
multipler: 3600.0
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is: C00101
initial concentration: 0.46
has only substance units: false
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is: CHEBI:20506
initial amount: NaN

616258
stoichiometry: 1.0
species: 990795
type: SpeciesReference

W3 CDTF: Wed Jun 29 11:22:41 BST 2005

614315
value: 59.0
type: LocalParameter

616968
value: 0.42
type: LocalParameter

616764
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species: 990775
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990475
is: CHEBI:15641
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is: C00440
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initial concentration: 1.63
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boundary condition: false
name: 5-methyl-tetrahydrofolate
type: Species

616209
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species: 990674
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614267
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615716
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615005
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991456
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is version of: http://identifiers.org/ec-code/6.3.2.17
fast: false
reversible: false
type: Reaction

616161
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species: 990655
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990375
is version of: C00415
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is version of: CHEBI:15633
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constant: false
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initial concentration: 0.0024
boundary condition: true

615980
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species: 990655
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613880
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990994
is: C05330
is: CHEBI:17230
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initial concentration: 10.0
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616812
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species: 990595
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990974
is: C00005
is: CHEBI:16474
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991328
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is version of: http://identifiers.org/ec-code/6.3.4.17
is: R02238
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614594
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is version of: GO:0008517
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615017
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614279
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metaid_0000085
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notes: Default unit of substance redefined to micromole by comparison with the article. Nicolas Le Novere
name: micromole (new default)
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is version of: http://identifiers.org/ec-code/6.3.4.3
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metaid_0000086
unit: 613843
notes: Default unit of time redefined to hour by comparison with the article. Nicolas Le Novere
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614993
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species: 990435
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615378
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614170
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616221
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614873
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617160
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616632
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990915
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614607
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616511
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616294
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616572
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990714
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991798
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615089
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990795
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991635
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is version of: GO:0008517
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614533
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614461
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species: 990435
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in compartment: 990318
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616379
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BIOMD0000000018
reaction: 991516
species: 990554
reaction: 991758
reaction: 991242
compartment: 990318
reaction: 992016
reaction: 991149
name: Morrison1989_FolateCycle
notes: This is a folate model that includes folate polyglutamation. Morrison and Allegra, JBC:264,10552-10566 (1989) Folate cycle kinetics in breast cancer cells Note: two flow BCs were converted into two downstream concentration BCs, thus removing the GAR and dUMP state variables. This dropped the number of ODEs from 21 to 19. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
reaction: 991269
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reaction: 991655
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species: 990895
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reaction: 991380
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species: 990775
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is described by: http://identifiers.org/pubmed/2732237
reaction: 991698
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reaction: 991838
reaction: 991818
reaction: 991798
reaction: 991130
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is version of: GO:0046655
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occurs in: http://identifiers.org/taxonomy/9606
reaction: 991557
species: 990475
reaction: 991170

991675
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616908
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991204
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is: R04560
is version of: http://identifiers.org/ec-code/2.1.2.3
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modifier: 614909
modifier: 614957
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is: REACT 812

990775
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991017
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is: R00945
is version of: http://identifiers.org/ec-code/2.1.2.1
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614497
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614375
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614581
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991996
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type: Reaction

616560
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species: 990615
type: SpeciesReference

616547
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type: LocalParameter

615353
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type: LocalParameter

614339
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type: LocalParameter

617040
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species: 990775
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615390
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617268
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991718
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product: 616644
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fast: false
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615872
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615560
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614485
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991130
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is version of: http://identifiers.org/ec-code/2.1.1.13
reactant: 614375
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614387
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species: 990994
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614327
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617052
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614109
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991698
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fast: false
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991916
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modifier: 617220
product: 617208
fast: false
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617100
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614861
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615884
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615366
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991398
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reactant: 615872
is version of: http://identifiers.org/ec-code/6.3.2.17
fast: false
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615197
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species: 990815
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614801
value: 60.0
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615860
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type: LocalParameter

616100
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type: LocalParameter

991170
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is version of: http://identifiers.org/ec-code/2.1.2.2
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modifier: 614646
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616306
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990874
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617196
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615764
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615800
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616992
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615426
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615101
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ORG:
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n:
  given: Nicolas
  family: Le Novère

615512
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type: Species

ORG:
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n:
  given: Tomas
  family: Radivoyevitch

616728
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615776
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type: LocalParameter

615908
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type: LocalParameter

615317
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990854
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614025
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is version of: http://identifiers.org/ec-code/6.3.2.17
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616064
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615500
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616644
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616391
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615414
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615572
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615329
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615740
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616692
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615668
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614146
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615173
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991557
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617448
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613928
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615402
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615125
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614750
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615968
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614557
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990332
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614363
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616680
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616016
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991516
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is: http://identifiers.org/ec-code/3.4.19.9
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615752
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616318
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617484
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991896
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modifier: 617172
reactant: 617160
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614134
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615185
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991536
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is: http://identifiers.org/ec-code/3.4.19.9
fast: false
reversible: false
type: Reaction

616668
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614545
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type: LocalParameter

991838
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product: 617004
product: 616992
reactant: 616980
fast: false
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615113
stoichiometry: 1.0
species: 990955
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614351
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990534
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is: CHEBI:16842
constant: false
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614049
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613856
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616148
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616487
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617388
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613904
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615065
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614448
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616270
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614085
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616920
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613868
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615488
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615956
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615548
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616788
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615161
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990394
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616884
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991437
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615077
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617436
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613916
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614158
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990694
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616608
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614837
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614097
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614436
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616872
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991380
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614737
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991099
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614013
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991038
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991058
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991269
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991956
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991758
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614724
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615788
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616052
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616463
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617364
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616124
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614763
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990935
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991078
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617400
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615041
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990615
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615451
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615932
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990414
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616860
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991496
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616980
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991476
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613988
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614776
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617340
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990318
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615209
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614073
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991302
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991818
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616704
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614000
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615053
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990554
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616800
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616112
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617352
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991242
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614813
value: 43.0
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W3 CDTF: Thu Jul 05 15:40:37 BST 2012