815455
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_4baf0e2c_52d1_4b4a_9381_66e377d44057
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0f4b4b05_f9cd_41d0_b4eb_d52b78cbc993
stoichiometry: 1.0
species: 801821
type: SpeciesReference

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stoichiometry: 1.0
species: 803411
type: SpeciesReference

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stoichiometry: 1.0
species: 803021
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_55cddeb5_9678_41eb_b44f_74781df38e50
value: 100.0
type: LocalParameter

823304
name: phosphorylation of RAF on scaffold
type: Reaction
reversible: false
is version of: GO:0000185
fast: false
is version of: http://identifiers.org/ec-code/2.7.11.1
is version of: GO:0008349

http://identifiers.org/biomodels.db/BIOMD0000000014#_7fa8e2ce_5cb3_4908_b821_205c804e9ea6
stoichiometry: 1.0
species: 802631
type: SpeciesReference

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stoichiometry: 1.0
species: 803531
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c145f423_58b4_4414_b059_2261e548aec6
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_05d1176e_6d31_438b_927e_39076846f276
value: 0.0
type: LocalParameter

818614
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_641d4e92_6f8b_4cb3_94b4_0edbe7176137
stoichiometry: 1.0
species: 802901
type: SpeciesReference

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stoichiometry: 1.0
species: 803322
type: SpeciesReference

804185
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_112bf8f8_d469_4c33_b1d8_b5250f1c99a1
stoichiometry: 1.0
species: 803261
type: SpeciesReference

819595
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#fa6f76fe_bb2e_4c68_a2f4_85a10f55076a
stoichiometry: 1.0
species: 802451
type: SpeciesReference

811885
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7bbf4bd2_b8ee_4b72_945c_1ad23a717f66
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b7c35366_147d_48c4_bfa5_06dbe374bac6
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 803621
type: SpeciesReference

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stoichiometry: 1.0
species: 801851
type: SpeciesReference

813145
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#dfc9abfe_9875_402c_99e8_9fd9e0a454c7
stoichiometry: 1.0
species: 801821
type: SpeciesReference

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stoichiometry: 1.0
species: 801641
type: SpeciesReference

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stoichiometry: 1.0
species: 801641
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 802961
type: SpeciesReference

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b6628246_14fe_4587_8cb6_413a549f4b0c
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
species: 803231
type: SpeciesReference

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stoichiometry: 1.0
species: 803441
type: SpeciesReference

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stoichiometry: 1.0
species: 802421
type: SpeciesReference

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stoichiometry: 1.0
species: 802451
type: SpeciesReference

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stoichiometry: 1.0
species: 802451
type: SpeciesReference

805445
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK_MEK-PP
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_16319d2a_605a_4856_a47f_09867cd99f0e
stoichiometry: 1.0
species: 801731
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

822464
reversible: false
is version of: GO:0008349
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.11.1
fast: false
name: phosphorylation of RAF on scaffold
is version of: GO:0000185

http://identifiers.org/biomodels.db/BIOMD0000000014#f19fd6db_d67f_46d3_80b4_622d173b1026
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_379ff860_419c_48e8_a019_9911a309026a
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#e3014a95_7397_4985_b2d7_20558fdb3854
stoichiometry: 1.0
species: 802901
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_64169fd2_1c1c_4c88_bf71_28ea51e84e63
stoichiometry: 1.0
species: 802631
type: SpeciesReference

814755
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#b9c08bdc_4db7_44ea_9e1b_a15d379ad9a5
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0a7be3c6_271f_487d_8b46_986e293d09c1
value: 100.0
type: LocalParameter

822534
is version of: GO:0031435
reversible: false
is version of: REACT 996
name: binding of RAF and RAFK
type: Reaction
fast: false

823514
type: Reaction
name: phosphorylation of RAF on scaffold
is version of: http://identifiers.org/ec-code/2.7.11.1
is version of: GO:0008349
reversible: false
fast: false
is version of: GO:0000185

http://identifiers.org/biomodels.db/BIOMD0000000014#_91dc7fc5_3e7d_4ef3_a9cf_daa385b3f8ec
value: 0.05
type: LocalParameter

805375
fast: false
reversible: false
is version of: GO:0031434
is homolog to: REACT 495
type: Reaction
is homolog to: REACT 1780
name: binding of MAPK and MEK-PP
is version of: GO:0051019

http://identifiers.org/biomodels.db/BIOMD0000000014#_8e525dd9_63ad_4921_86a8_35f8adf48400
stoichiometry: 1.0
species: 801582
type: SpeciesReference

822254
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.11.1
reversible: false
is version of: GO:0008349
name: phosphorylation of RAF on scaffold
fast: false
is version of: GO:0000185

http://identifiers.org/biomodels.db/BIOMD0000000014#_9f1737ed_2c43_4783_b4c8_49667e1fd47e
stoichiometry: 1.0
species: 802362
type: SpeciesReference

817078
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_2d195bae_1111_40bf_9717_400c5ef1e602
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#ce973f13_0ed2_43b2_95da_9f09f90096e3
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_059d6a61_81b3_4403_8e13_5447cde55c71
stoichiometry: 1.0
species: 801911
type: SpeciesReference

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stoichiometry: 1.0
species: 803201
type: SpeciesReference

801671
is version of: P26696
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: MAPK-P
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_59e1af75_acef_4cbf_8541_201e7d974538
stoichiometry: 1.0
species: 802842
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_190c557f_a57e_4915_8be6_7aea02dbd9fb
stoichiometry: 1.0
species: 803501
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c4bbc363_ed68_487d_818e_7c293e8282c0
stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_990ce321_868c_41ed_9a62_33b757ea3d5a
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#ea35e9e0_254b_4df3_931f_275afee2ae9a
stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 803861
type: SpeciesReference

808455
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_6b8e22aa_005e_4744_bf60_c7252de5de95
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#cf77fff7_990e_46bf_8c39_d91fe0c8b6d4
value: 0.0
type: LocalParameter

804071
initial amount: 0.0
has part: P09560
name: Scaffold_MAPK-PP_MEK-PP_RAF
in compartment: 801486
has only substance units: true
has part: Q05116
has part: P26696
initial concentration: NaN
boundary condition: false
type: Species
constant: false

818545
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_4cbe9ea2_bc16_4c44_af34_1d6a790e1bda
stoichiometry: 1.0
species: 802181
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_599c70c3_5f12_41aa_aee1_f044b530d26b
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_63180cb7_cb94_4b91_b698_c764859c2721
stoichiometry: 1.0
species: 802511
type: SpeciesReference

803651
name: Scaffold_MEK_RAF
constant: false
in compartment: 801486
boundary condition: false
has part: P09560
initial concentration: NaN
has only substance units: true
has part: Q05116
initial amount: 0.0
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_037e3d14_8a43_4d93_a2d5_9b3173eea55f
stoichiometry: 1.0
species: 801671
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

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stoichiometry: 1.0
species: 801641
type: SpeciesReference

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stoichiometry: 1.0
species: 801701
type: SpeciesReference

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stoichiometry: 1.0
species: 803201
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cc515283_54ad_4840_bb15_352f1b098df5
stoichiometry: 1.0
species: 802961
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_9f82639d_5ea5_47a7_b2bd_eb7331a1d83f
stoichiometry: 1.0
species: 802121
type: SpeciesReference

814338
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_37ba6a35_6e75_4008_9dac_7dfcfeecd7a9
stoichiometry: 1.0
species: 803322
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bfac15eb_8760_46ee_bf17_15a4be46225c
stoichiometry: 1.0
species: 801791
type: SpeciesReference

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stoichiometry: 1.0
species: 801552
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5e0de32a_905b_4cda_8c37_d0f3529d67a5
value: 0.05
type: LocalParameter

810135
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

BIOMD0000000014
reaction: 819804
species: 801731
reaction: 815875
reaction: 824496
reaction: 809715
species: 803501
reaction: 823934
reaction: 804118
species: 803891
reaction: 814125
reaction: 817634
reaction: 812375
is version of: GO:0000165
reaction: 818545
reaction: 808945
species: 802812
species: 802751
species: 802151
reaction: 806705
species: 802842
reaction: 811675
species: 803861
reaction: 815805
species: 802961
reaction: 808595
reaction: 818195
reaction: 822674
reaction: 819734
reaction: 815315
reaction: 812025
reaction: 819246
reaction: 815525
reaction: 810135
reaction: 821137
reaction: 812235
reaction: 818405
reaction: 819314
species: 802661
reaction: 812935
reaction: 824074
species: 803201
species: 803981
species: 802781
reaction: 804325
reaction: 824704
reaction: 807965
reaction: 812305
reaction: 808455
reaction: 806075
reaction: 806355
reaction: 814055
species: 803322
volume units: metaid_0000029
species: 801521
reaction: 809155
reaction: 818614
reaction: 818824
reaction: 807475
reaction: 810205
reaction: 821187
reaction: 807685
species: 803171
substance units: metaid_0000053
reaction: 820015
reaction: 823444
reaction: 805445
reaction: 812865
reaction: 812585
species: 802092
reaction: 814549
reaction: 821437
reaction: 818264
reaction: 806005
reaction: 808315
reaction: 823864
reaction: 815175
reaction: 806215
reaction: 823164
reaction: 811045
reaction: 813775

http://identifiers.org/biomodels.db/BIOMD0000000014#c20677eb_edeb_4461_9352_52d783b1c820
stoichiometry: 1.0
species: 801761
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#fc41d057_ccea_4068_8023_a9584c361efc
stoichiometry: 1.0
species: 802871
type: SpeciesReference

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stoichiometry: 1.0
species: 802661
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 802301
type: SpeciesReference

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stoichiometry: 1.0
species: 802931
type: SpeciesReference

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stoichiometry: 1.0
species: 802211
type: SpeciesReference

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stoichiometry: 1.0
species: 803261
type: SpeciesReference

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stoichiometry: 1.0
species: 802421
type: SpeciesReference

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stoichiometry: 1.0
species: 802602
type: SpeciesReference

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stoichiometry: 1.0
species: 802301
type: SpeciesReference

802092
has part: Q05116
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: MEK-PP_MEKPase
type: Species

802271
has part: Q05116
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_MEK
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#bda05dd8_5753_42df_8536_c9010f76c958
stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cbdce37a_2952_4f52_8184_393ae062877f
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_77322f92_6d42_4aa6_b6fc_e6a887eac66a
stoichiometry: 1.0
species: 802901
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_2b779f9d_0950_4599_8c39_471cef7b67e5
stoichiometry: 1.0
species: 801552
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 803531
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ee35cb09_c869_4ed1_abe5_deea605a5a13
value: 0.1
type: LocalParameter

811325
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

804815
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P_MEKPase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#f690f3c7_60c6_4f3e_97c2_3f5b1bf03195
stoichiometry: 1.0
species: 802812
type: SpeciesReference

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stoichiometry: 1.0
species: 801821
type: SpeciesReference

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stoichiometry: 1.0
species: 802332
type: SpeciesReference

823094
fast: false
is version of: GO:0008349
type: Reaction
is version of: GO:0000185
reversible: false
is version of: http://identifiers.org/ec-code/2.7.11.1
name: phosphorylation of RAF on scaffold

http://identifiers.org/biomodels.db/BIOMD0000000014#_0d75b9fd_d178_48fa_bc88_179283a5582e
stoichiometry: 1.0
species: 802961
type: SpeciesReference

816575
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_70bac7e1_436a_4bd1_b884_036f46597df7
stoichiometry: 1.0
species: 802392
type: SpeciesReference

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stoichiometry: 1.0
species: 803471
type: SpeciesReference

819174
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 803741
type: SpeciesReference

814265
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#ac55f8ac_8a73_4bce_8e40_86fb2055de94
stoichiometry: 1.0
species: 802931
type: SpeciesReference

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stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

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stoichiometry: 1.0
species: 802991
type: SpeciesReference

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stoichiometry: 1.0
species: 802392
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stoichiometry: 1.0
species: 801671
type: SpeciesReference

816365
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#a1ed100b_145f_449d_ae8a_0d3171259f9e
value: 0.1
type: LocalParameter

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stoichiometry: 1.0
species: 803171
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stoichiometry: 1.0
species: 801761
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stoichiometry: 1.0
species: 802541
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cc0fd572_5735_4962_a2e7_b4afd0236ae9
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_1feb9386_f617_4587_8bec_3d0f89b0ec26
stoichiometry: 1.0
species: 802481
type: SpeciesReference

803831
type: Species
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constant: false
name: Scaffold_MAPK_MEK-PP_RAF
boundary condition: false
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initial concentration: NaN
in compartment: 801486
has only substance units: true
initial amount: 0.0

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stoichiometry: 1.0
species: 801851
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stoichiometry: 1.0
species: 802332
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817145
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

807615
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#fe79eba3_d519_4244_b4a7_b75bb3b10f3b
stoichiometry: 1.0
species: 803201
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_481254b8_2888_4570_95db_0cff67b7dc1c
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
species: 802481
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stoichiometry: 1.0
species: 801582
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stoichiometry: 1.0
species: 801821
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802842
has part: P09560
boundary condition: false
in compartment: 801486
initial amount: 0.0
type: Species
name: Scaffold_MAPK_MEK-PP_RAF
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has only substance units: true
initial concentration: NaN
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constant: false

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stoichiometry: 1.0
species: 803501
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stoichiometry: 1.0
species: 802721
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stoichiometry: 1.0
species: 802931
type: SpeciesReference

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stoichiometry: 1.0
species: 802362
type: SpeciesReference

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stoichiometry: 1.0
species: 801701
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stoichiometry: 1.0
species: 801791
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stoichiometry: 1.0
species: 802511
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_8a525a57_f55c_4433_9971_05ea777f174b
value: 10.0
type: LocalParameter

811255
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

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stoichiometry: 1.0
species: 802602
type: SpeciesReference

805026
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P_RAF-P
type: Reaction

802121
has part: P09560
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: RAF_RAFK
type: Species

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stoichiometry: 1.0
species: 803021
type: SpeciesReference

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stoichiometry: 1.0
species: 802602
type: SpeciesReference

812515
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

816504
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#ffa5b305_4cd8_42d0_9556_71c50e709e86
stoichiometry: 1.0
species: 802271
type: SpeciesReference

821834
type: Reaction
is version of: GO:0000185
is version of: GO:0008349
fast: false
reversible: false
is version of: http://identifiers.org/ec-code/2.7.11.1
name: phosphorylation of RAF on scaffold

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

813216
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_440b9c8a_ac1c_43a7_af03_4a5ecb500700
value: 0.05
type: LocalParameter

819385
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_11377573_d7e8_4668_836f_34e2167e2e06
value: 0.5
type: LocalParameter

803501
type: Species
initial concentration: NaN
in compartment: 801486
name: Scaffold_MAPK-PP_MEK-P_RAF-P
constant: false
initial amount: 0.0
has part: P09560
has only substance units: true
has part: Q05116
boundary condition: false
has part: P26696

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stoichiometry: 1.0
species: 803231
type: SpeciesReference

816155
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_1418b733_8aa5_493f_b08b_a9feb57caec6
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_58674c5b_ba87_4c2d_9354_14b21d02aaf7
value: 0.05
type: LocalParameter

809925
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_1962e683_bffd_456f_88b1_a577d3cc8f4d
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_347bf415_f174_4630_88c9_c1499301bb04
value: 0.0
type: LocalParameter

803201
name: Scaffold_MAPK-P_MEK-PP_RAF
in compartment: 801486
type: Species
initial concentration: NaN
has only substance units: true
boundary condition: false
has part: P26696
has part: Q05116
has part: P09560
constant: false
initial amount: 0.0

http://identifiers.org/biomodels.db/BIOMD0000000014#e3503a29_7eab_454a_a087_5333a851e2de
stoichiometry: 1.0
species: 801641
type: SpeciesReference

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stoichiometry: 1.0
species: 802721
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_4fd78910_731a_43a5_aeb0_39cfab7d8605
value: 1.0
type: LocalParameter

823164
fast: false
name: binding of RAF and RAFK
reversible: false
is version of: REACT 996
type: Reaction
is version of: GO:0031435

http://identifiers.org/biomodels.db/BIOMD0000000014#_69e7b415_3b43_4e69_9408_63554a66bd73
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 802211
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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

809715
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

811955
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_672e84f4_296a_4b02_8c30_341f34162703
stoichiometry: 1.0
species: 802451
type: SpeciesReference

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stoichiometry: 1.0
species: 801791
type: SpeciesReference

807545
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_5727d1a4_c3b9_46e4_bb90_5b4feba3bead
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_6f5b8be9_f05f_4b4a_afe3_21f981f9276d
stoichiometry: 1.0
species: 802602
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http://identifiers.org/biomodels.db/BIOMD0000000014#ed5cb674_48bc_47fc_bdcb_b888a2c0c803
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#e8f284f9_1b43_4201_82e3_bdd751ceb36c
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
species: 801701
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stoichiometry: 1.0
species: 802931
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stoichiometry: 1.0
species: 802001
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stoichiometry: 1.0
species: 803651
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801521
is: Q90W58
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.3
in compartment: 801486
name: MAPK phosphatase
type: Species

820154
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_09c25a52_a17d_4068_ba50_8a7fbcb30e9c
stoichiometry: 1.0
species: 801761
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stoichiometry: 1.0
species: 803771
type: SpeciesReference

815805
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

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stoichiometry: 1.0
species: 801731
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stoichiometry: 1.0
species: 802271
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805865
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P_MEK-PP
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#bcdbf392_6a4e_41f7_a077_a4b02e8c1d41
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
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802421
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initial amount: 0.0
constant: false
boundary condition: false
has only substance units: true
type: Species
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name: Scaffold_MEK-P_RAF-P
in compartment: 801486
initial concentration: NaN

803141
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type: Species
constant: false
initial concentration: NaN
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initial amount: 0.0
has only substance units: true
name: Scaffold_MAPK-P_MEK-P_RAF-P
boundary condition: false

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stoichiometry: 1.0
species: 801582
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821087
is: GO:0004709
is: http://identifiers.org/ec-code/2.7.1.37
fast: false
reversible: false
name: phosphorylation of MEK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_5fa45056_19f3_4d47_8209_6368210c764b
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#fc377dbb_3f5e_4084_92af_b52b28f68b12
value: 5.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_1f8b6418_e760_447a_90e5_ab6da70a23f1
stoichiometry: 1.0
species: 801821
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stoichiometry: 1.0
species: 803861
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803291
initial concentration: NaN
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boundary condition: false
initial amount: 0.0
has part: P26696
name: Scaffold_MAPK-PP_RAF
constant: false
type: Species
has part: P09560
in compartment: 801486

823724
is version of: http://identifiers.org/ec-code/2.7.11.1
is version of: GO:0008349
fast: false
is version of: GO:0000185
name: phosphorylation of RAF on scaffold
reversible: false
type: Reaction

802631
initial amount: 0.0
in compartment: 801486
initial concentration: NaN
has part: Q05116
constant: false
type: Species
name: Scaffold_MAPK_MEK
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boundary condition: false
has only substance units: true

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stoichiometry: 1.0
species: 803471
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_04986bce_3a72_4652_8eee_9d65e617d065
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#cff80b39_1bf3_47c2_9ef6_99f457b888d2
stoichiometry: 1.0
species: 801701
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http://identifiers.org/biomodels.db/BIOMD0000000014#_8c9318b5_c036_4e2a_b2a9_4a94c23c2cc0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#b3b63f72_2b15_485d_b6bf_c3b8dd5a753b
value: 0.0
type: LocalParameter

801701
is version of: P26696
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: MAPK-PP
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_3abe209e_3351_4be6_ae07_fa479e35ea55
stoichiometry: 1.0
species: 802332
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_64f9a5a8_5f09_403d_b26e_236ec6fcc7d8
value: 0.1
type: LocalParameter

803471
has only substance units: true
type: Species
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initial amount: 0.0
initial concentration: NaN
name: Scaffold_MAPK-PP_MEK-P_RAF
constant: false
in compartment: 801486
boundary condition: false
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 804011
type: SpeciesReference

814405
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_20ad40ea_edae_4830_8b82_dd8af9b7ae05
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#c89c3021_2aa6_47c7_a842_6ebebd715d22
stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 802451
type: SpeciesReference

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stoichiometry: 1.0
species: 802661
type: SpeciesReference

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stoichiometry: 1.0
species: 802241
type: SpeciesReference

801791
is: Q05116
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: MEK-PP
type: Species

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 801882
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b1dedcc6_35d1_4b04_98d4_8d5296d5b077
value: 0.5
type: LocalParameter

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stoichiometry: 1.0
species: 803591
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stoichiometry: 1.0
species: 802271
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#dd95ad8e_4e03_491a_9742_7a2236d038b3
value: 10.0
type: LocalParameter

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value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#a5864639_19b8_455d_9b98_42b8c016b464
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_29a535bc_0803_473b_b3d4_bdbd03c43b33
stoichiometry: 1.0
species: 802241
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c5e4b0c7_77f1_4fbe_a924_16d6e37054de
stoichiometry: 1.0
species: 803382
type: SpeciesReference

820887
is: GO:0004708
is: http://identifiers.org/ec-code/2.7.1.37
fast: false
reversible: false
name: phosphorylation of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_85ae49e0_9222_49cd_bc99_6197416c2aea
stoichiometry: 1.0
species: 803201
type: SpeciesReference

807265
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_0c7a510c_ab77_491d_9fdc_b0f2b73601d2
stoichiometry: 1.0
species: 802812
type: SpeciesReference

812445
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

822394
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

807405
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_28d6f2c7_4b95_4a2f_a6d5_d5cfa6d295a0
stoichiometry: 1.0
species: 803801
type: SpeciesReference

806845
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#c68d14e6_4f88_4b2b_9b8a_c5614fb57dcc
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_41511ab3_7ab1_4309_af3c_1075225f6735
stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6728e009_6e40_4642_9e2a_6898f81b8628
stoichiometry: 1.0
species: 803591
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b954c738_ade1_4f60_9642_a2e4b072579f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_1c5b174d_ff29_4af1_96b1_c39b544c3ce8
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#f0dfe197_da2a_4cd6_9014_523b33af0778
stoichiometry: 1.0
species: 801671
type: SpeciesReference

806775
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

808035
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_16f15beb_f52f_4390_8623_6119e2761b99
stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_4fd5263b_bf25_4fa8_b4a9_afeeef883941
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a1c912e1_e44a_43ac_b4e8_9318893ffd96
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#b8a26763_bfae_4e04_93d4_e8ffae37f89f
stoichiometry: 1.0
species: 801761
type: SpeciesReference

809575
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#c48bf010_2baa_482d_a9ff_c8393e8e424f
stoichiometry: 1.0
species: 802451
type: SpeciesReference

802392
initial concentration: NaN
name: Scaffold_MEK-P_RAF
constant: false
has part: P09560
in compartment: 801486
has only substance units: true
has part: Q05116
boundary condition: false
type: Species
initial amount: 0.0

http://identifiers.org/biomodels.db/BIOMD0000000014#_8d1fe041_b7fb_4417_87b1_d5d08976e9db
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#af704877_1794_4e58_81b6_65dfcc365332
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0693ef50_1e2f_48ae_89d8_84623360f842
stoichiometry: 1.0
species: 802092
type: SpeciesReference

805935
is version of: http://identifiers.org/ec-code/2.7.1.37
is version of: GO:0000187
name: phosphorylation of MAPK-P
is version of: GO:0004708
reversible: false
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_8e8bcf34_1375_479c_a922_330c73ba52c8
stoichiometry: 1.0
species: 803561
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_716123fd_91a6_4657_afe1_bcc7a31cb8a9
stoichiometry: 1.0
species: 803501
type: SpeciesReference

803322
boundary condition: false
name: Scaffold_MAPK-PP_RAF-P
has part: P09560
initial concentration: NaN
in compartment: 801486
constant: false
initial amount: 0.0
type: Species
has part: P26696
has only substance units: true

http://identifiers.org/biomodels.db/BIOMD0000000014#_9369fa2c_5802_41ed_b8d4_07be685bdbac
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#cc5e55b5_4564_4bf6_9145_e1338da9149f
stoichiometry: 1.0
species: 802842
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#fe778619_29b9_4bc4_804d_3cab30a5ac00
stoichiometry: 1.0
species: 801941
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6ba3b5c5_13f8_49b2_9e1a_cbcbb0f2210b
stoichiometry: 1.0
species: 803231
type: SpeciesReference

803082
has only substance units: true
type: Species
has part: P26696
in compartment: 801486
initial amount: 0.0
constant: false
has part: Q05116
initial concentration: NaN
boundary condition: false
name: Scaffold_MAPK-P_MEK-P

http://identifiers.org/biomodels.db/BIOMD0000000014#d1f69740_d730_467e_94dd_e26a38febce9
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ce139a44_b5c8_45be_8f98_18317c81b3f3
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_52361433_dea6_4914_bbad_07e5e43dbc9d
stoichiometry: 1.0
species: 801552
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cfc0a2fa_aa3c_46fb_9947_cc28bb14e810
stoichiometry: 1.0
species: 802301
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_1abe8ac2_49e5_4b33_a101_2452146f6899
stoichiometry: 1.0
species: 802481
type: SpeciesReference

801971
initial amount: 0.0
has part: P09560
name: MEK-P_RAF-P
in compartment: 801486
initial concentration: NaN
type: Species
has part: Q05116
has only substance units: true
boundary condition: false
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_7253d44e_552a_4897_abad_538b3bb8fa65
stoichiometry: 1.0
species: 803501
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3066dfc2_3a70_4d98_a776_a71e33bb115e
value: 0.05
type: LocalParameter

816994
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

822604
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

802991
type: Species
has only substance units: true
name: Scaffold_MAPK-P_MEK
has part: P26696
boundary condition: false
in compartment: 801486
constant: false
initial amount: 0.0
initial concentration: NaN
has part: Q05116

http://identifiers.org/biomodels.db/BIOMD0000000014#_9997a17d_b2e6_484f_9d48_7ee0a2e23178
stoichiometry: 1.0
species: 801641
type: SpeciesReference

808385
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_063151dc_dd38_4f37_aa60_6423016a0184
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_8bc6f010_ca44_48a9_b280_eb85a34bc94a
stoichiometry: 1.0
species: 802421
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6535cb9f_0f1e_4999_b5d5_4bac0d613b1e
stoichiometry: 1.0
species: 803681
type: SpeciesReference

803771
constant: false
initial concentration: NaN
has only substance units: true
initial amount: 0.0
name: Scaffold_MAPK_MEK_RAF
boundary condition: false
has part: Q05116
type: Species
has part: P26696
has part: P09560
in compartment: 801486

821974
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

802901
has part: P26696
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_MAPK-P
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_3d8e7cd2_4def_4a74_a715_d13cb353c7f4
stoichiometry: 1.0
species: 802961
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_8cfe5b51_f7d5_40ef_aafd_409ca23b863c
stoichiometry: 1.0
species: 801671
type: SpeciesReference

814895
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#ef1a79b7_a2e3_4a34_a720_f0232c309d06
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_869db5ef_4e06_4f16_a1a5_f8d2ed90ac8a
stoichiometry: 1.0
species: 802721
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#da663df2_ec76_4398_88ea_619fcefef994
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_769f2ca5_8117_4faf_b760_fdb977d05362
stoichiometry: 1.0
species: 803591
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_1c2337c2_1247_4329_8c77_6e524e05f389
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_633e0f8d_0a94_4063_be69_c16c52c178a2
stoichiometry: 1.0
species: 802392
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_2bdfce05_db0c_4558_9d30_84611481d650
stoichiometry: 1.0
species: 803201
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5cb0b6c7_18bc_4697_8778_f74eaafbdef6
stoichiometry: 1.0
species: 802241
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3be71f51_8bb4_4552_8f23_0c241b79ffa5
stoichiometry: 1.0
species: 802181
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_62263366_f924_4595_8b31_5cece8082296
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_40b350b5_4fc3_4d47_8968_1c40bc9e09b7
stoichiometry: 1.0
species: 802392
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f36f0219_835a_464a_ad53_7af2e55518cf
stoichiometry: 1.0
species: 801641
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7ae0e985_c77a_45de_8a5e_08f096f8c8bb
stoichiometry: 1.0
species: 801641
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ea096f98_1334_470e_ab70_a52dc129f39a
stoichiometry: 1.0
species: 803111
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_922d8eed_f077_43ce_9b61_2ada1ecb1001
stoichiometry: 1.0
species: 802241
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3d08feee_f265_49f8_963a_5ceec92a72d6
stoichiometry: 1.0
species: 802901
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6ab47ba3_e00d_44d9_aec3_2146c074891c
value: 5.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_87223da5_e7c8_46a4_b1dd_451b8d58e633
stoichiometry: 1.0
species: 801911
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c3e141fa_da75_4c6b_8f34_0287bb86e4a8
stoichiometry: 1.0
species: 801701
type: SpeciesReference

822186
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_09c9cc23_a692_4479_b50c_62d00c2f27cd
stoichiometry: 1.0
species: 802061
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_79d5cbdd_b6b9_48a9_8b68_3683dea7cfd3
stoichiometry: 1.0
species: 802751
type: SpeciesReference

805655
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P_MAPKPase
type: Reaction

808175
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7eaa4e4d_5c76_445a_acbc_d734d8aba216
stoichiometry: 1.0
species: 802991
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_38cfbb5e_23d6_4e76_9090_4d40a53316dd
stoichiometry: 1.0
species: 802211
type: SpeciesReference

819664
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#daad4d00_8347_4c61_b917_890ad1693a5e
stoichiometry: 1.0
species: 803171
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b33debd9_6d67_4aab_a079_6ccba4fde7d9
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_89045aaa_5b94_4b10_85d5_dae96dac4917
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_2f339d0a_1b61_4f9e_b4de_25dfa728479b
stoichiometry: 1.0
species: 802691
type: SpeciesReference

819734
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

821337
is: GO:0000186
name: phosphorylation of MEK-P on scaffold
is: http://identifiers.org/ec-code/2.7.1.37
type: Reaction
is: GO:0004709
fast: false
reversible: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_5c947169_0bbf_4443_befa_d97bf877bb67
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_07866f8d_887a_4c52_9aa2_d03201eea6a1
stoichiometry: 1.0
species: 802211
type: SpeciesReference

814965
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#f5ea3645_fa26_40df_a525_ffd699f847cd
stoichiometry: 1.0
species: 802421
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#fdd713fd_b42a_4b41_bf0e_7319904de042
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5fd81424_d156_4aa7_8000_b5301816701e
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a384e7a0_770b_4bd8_ba0e_3509b8ad4d9b
stoichiometry: 1.0
species: 803291
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b0063278_6ec7_4e35_9092_1a1eb7073990
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3e68905c_c28a_4636_bd86_5369d34defc5
stoichiometry: 1.0
species: 802181
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c4f982ad_46ff_4222_91e4_5e2b19b87015
value: 0.0
type: LocalParameter

814055
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

804745
is version of: GO:0031435
fast: false
reversible: false
name: binding of MEK-P and MEK phosphatase
type: Reaction

802571
has only substance units: true
name: Scaffold_MAPK_RAF
boundary condition: false
has part: P09560
initial amount: 0.0
initial concentration: NaN
in compartment: 801486
constant: false
has part: P26696
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#bd6df03b_8af9_42ca_9e73_8fed8e1dc4ce
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#be9fdd7b_752d_4ff7_a2ed_c2baa9124245
stoichiometry: 1.0
species: 802362
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_820ceeea_21b5_4eea_9aea_28108cdd2223
stoichiometry: 1.0
species: 801641
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_4e33ddf4_2960_45cf_a3c7_1d7998c4e61d
stoichiometry: 1.0
species: 803021
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_1508aa9a_79c3_4391_b2f8_bf9063547557
value: 0.6
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_9a81051c_e424_4dd9_a28e_1af2dd864830
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0a3fbc30_4d72_4b92_b790_670bb53f15fe
stoichiometry: 1.0
species: 802571
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_2ff704cb_b98c_4675_848a_6b60a7168ce7
stoichiometry: 1.0
species: 801582
type: SpeciesReference

821904
reversible: false
is version of: REACT 996
fast: false
name: binding of RAF and RAFK
type: Reaction
is version of: GO:0031435

http://identifiers.org/biomodels.db/BIOMD0000000014#ce375669_7fb6_41ab_97c0_c8e384df69a4
stoichiometry: 1.0
species: 801671
type: SpeciesReference

806495
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_02f50748_ba80_43af_974e_92c77c1d69d8
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_95df8f47_7272_489b_9808_e00bf3b244ea
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0d5fbd35_433e_4725_9be8_a4a9e1d6f29c
stoichiometry: 1.0
species: 803111
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_703dba14_db9c_475d_adb2_37e4e4e90795
stoichiometry: 1.0
species: 802392
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_489bac19_da8b_4a62_941c_e558fb567d8c
stoichiometry: 1.0
species: 803951
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5aba269a_bd24_4074_b9e7_9eda4c58d626
stoichiometry: 1.0
species: 802691
type: SpeciesReference

824774
is version of: http://identifiers.org/ec-code/2.7.11.1
type: Reaction
fast: false
reversible: false
is version of: GO:0000185
name: phosphorylation of RAF on scaffold
is version of: GO:0008349

http://identifiers.org/biomodels.db/BIOMD0000000014#_2a7855a6_6479_4b99_a669_90f511330381
stoichiometry: 1.0
species: 801521
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_4478c867_881b_465e_be10_fd730eac2699
stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f54b6d99_84bd_4548_8bfd_362a71b95260
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0ff89b51_e9b4_4dd0_8dc3_3b269c97b6d9
stoichiometry: 1.0
species: 802181
type: SpeciesReference

805515
type: Reaction
reversible: false
is version of: GO:0004708
name: phosphorylation of MAPK
fast: false
is homolog to: REACT 2247
is version of: http://identifiers.org/ec-code/2.7.12.2
is version of: GO:0006468
is homolog to: REACT 136

http://identifiers.org/biomodels.db/BIOMD0000000014#_0caa85d8_2322_4323_9f48_e7d251a51e03
stoichiometry: 1.0
species: 802271
type: SpeciesReference

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stoichiometry: 1.0
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817424
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

801641
is version of: P26696
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.4
in compartment: 801486
name: MAPK
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_1ecde70b_2846_4e1d_9854_386d51ba9b8c
value: 10.0
type: LocalParameter

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stoichiometry: 1.0
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http://identifiers.org/biomodels.db/BIOMD0000000014#_608d5261_4907_451b_8edd_207847ef65d1
value: 0.5
type: LocalParameter

817634
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

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stoichiometry: 1.0
species: 801641
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http://identifiers.org/biomodels.db/BIOMD0000000014#_4eac62b1_7df2_48da_8683_d1c7827a2f83
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 801521
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stoichiometry: 1.0
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value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 802362
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http://identifiers.org/biomodels.db/BIOMD0000000014#_15e7cacd_21e7_4f00_87a3_9bafe3468668
value: 0.05
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http://identifiers.org/biomodels.db/BIOMD0000000014#_11b859e4_338b_4b0a_bd5d_9c24e0f419fb
value: 10.0
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stoichiometry: 1.0
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802451
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constant: false
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initial concentration: NaN
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name: Scaffold_MEK-PP
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_1b75c4d7_f1d4_49e7_ac48_8ce692899ce0
value: 0.05
type: LocalParameter

803981
boundary condition: false
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initial concentration: NaN
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constant: false
in compartment: 801486
initial amount: 0.0
has part: P09560
has only substance units: true
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stoichiometry: 1.0
species: 802871
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http://identifiers.org/biomodels.db/BIOMD0000000014#_7b0d5429_db60_45d1_83d5_d66ba6fd858d
value: 0.05
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stoichiometry: 1.0
species: 802602
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 802241
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 803501
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810065
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
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value: 0.5
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 10.0
type: LocalParameter

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stoichiometry: 1.0
species: 802991
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stoichiometry: 1.0
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802721
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in compartment: 801486
initial amount: 0.0
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constant: false
initial concentration: NaN
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has part: P26696
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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821037
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is: GO:0004708
is: GO:0000187
is: http://identifiers.org/ec-code/2.7.1.37
name: phosphorylation of MAPK-P on scaffold
reversible: false

811117
is version of: GO:0051019
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reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

813775
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

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stoichiometry: 1.0
species: 802301
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804466
fast: false
is version of: GO:0006470
is version of: http://identifiers.org/ec-code/3.1.3.16
reversible: false
name: dephosphorylation of RAF-P
type: Reaction

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 0.05
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value: 0.0
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value: 0.0
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stoichiometry: 1.0
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819455
is version of: GO:0043241
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reversible: false
name: dissociation of RAF from scaffold
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812795
fast: false
reversible: false
name: binding of MEK on scaffold
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stoichiometry: 1.0
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804395
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P_RAFPase
type: Reaction

803051
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initial concentration: NaN
constant: false
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initial amount: 0.0
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stoichiometry: 1.0
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823234
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 0.05
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821555
is version of: GO:0043241
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reversible: false
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806986
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value: 0.1
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value: 0.5
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value: 0.0
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812375
fast: false
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808595
is version of: GO:0051019
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reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

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stoichiometry: 1.0
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value: 100.0
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stoichiometry: 1.0
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817565
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value: 0.0
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value: 0.1
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value: 0.0
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value: 0.5
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value: 10.0
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811185
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value: 0.0
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value: 0.0
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815105
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803382
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initial concentration: NaN
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constant: false
name: Scaffold_MAPK-PP_MEK_RAF
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value: 0.6
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value: 0.1
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809646
is version of: GO:0043241
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reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

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value: 0.4
type: LocalParameter

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value: 0.5
type: LocalParameter

821624
name: phosphorylation of RAF on scaffold
type: Reaction
fast: false
reversible: false
is version of: GO:0000185
is version of: GO:0008349
is version of: http://identifiers.org/ec-code/2.7.11.1

http://identifiers.org/biomodels.db/BIOMD0000000014#_1c2ae0bc_fe90_4886_bdf0_177989248c8e
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#b5b43fcd_81e9_4016_a772_506058332043
stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 803561
type: SpeciesReference

815525
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#fe4a51c5_25c7_4cac_9016_17cb0686b84a
stoichiometry: 1.0
species: 802901
type: SpeciesReference

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stoichiometry: 1.0
species: 802961
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bdb3b29e_9f4d_48ae_ade5_9838ab5c0cbf
stoichiometry: 1.0
species: 802571
type: SpeciesReference

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stoichiometry: 1.0
species: 803471
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#fca44226_204e_4d6d_bf4a_7e9a71297b6b
stoichiometry: 1.0
species: 802211
type: SpeciesReference

803621
has part: P09560
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_RAF
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_53b200e4_f254_41bf_a8eb_c9eeb3604bd1
stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
species: 803291
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
species: 803531
type: SpeciesReference

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stoichiometry: 1.0
species: 802241
type: SpeciesReference

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stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f50e8546_91f8_4df2_94cc_8a6bbf6cf8e8
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 803561
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c79d4022_5f44_479e_92b6_36e111b60d75
value: 0.5
type: LocalParameter

818405
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_9c7d7314_808f_4ac1_9b95_08327f4d870c
value: 0.0
type: LocalParameter

801851
is version of: P09560
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: RAF-P
type: Species

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stoichiometry: 1.0
species: 802211
type: SpeciesReference

806005
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP and MAPK phosphatase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7d1c7b9e_06b0_4bd5_88d8_ee77516ad22c
value: 0.0
type: LocalParameter

802871
has part: P26696
initial amount: 0.0
boundary condition: false
type: Species
has part: Q05116
in compartment: 801486
constant: false
has only substance units: true
name: Scaffold_MAPK_MEK-PP_RAF-P
initial concentration: NaN
has part: P09560

811536
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_28170848_1ccc_46ca_81dc_ae6bf74bbdfc
value: 0.05
type: LocalParameter

815945
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_54982ccb_63de_47e0_9afb_63128475bc3a
stoichiometry: 1.0
species: 802181
type: SpeciesReference

817845
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_0392bb20_729a_431c_b0f5_2af3457729fb
stoichiometry: 1.0
species: 801761
type: SpeciesReference

803591
name: Scaffold_MAPK-PP_MEK-PP_RAF-P
has part: P09560
has part: P26696
type: Species
has part: Q05116
in compartment: 801486
constant: false
has only substance units: true
initial amount: 0.0
boundary condition: false
initial concentration: NaN

http://identifiers.org/biomodels.db/BIOMD0000000014#_7e4abae7_9366_49d4_974a_785adeab4b69
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 803171
type: SpeciesReference

821187
is: GO:0004709
is: http://identifiers.org/ec-code/2.7.1.37
fast: false
reversible: false
name: phosphorylation of MEK on scaffold
type: Reaction

823024
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

802241
has part: P09560
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_RAF-P
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_5c52f0c8_b966_4b29_a390_ede009aeee1e
stoichiometry: 1.0
species: 801641
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_9683a867_65b5_40be_8f50_95efa3b3ab99
stoichiometry: 1.0
species: 802691
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

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stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
species: 802332
type: SpeciesReference

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stoichiometry: 1.0
species: 802181
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_12b05fae_59a8_40a9_a5a8_d92177849505
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7174f58a_7ee8_4af4_b564_0704448f9b97
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 801521
type: SpeciesReference

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stoichiometry: 1.0
species: 802602
type: SpeciesReference

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stoichiometry: 1.0
species: 802421
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bc4a5746_5f68_4443_9422_f42625f677f0
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_03030f36_047b_4262_990c_0cfeca96472f
value: 0.0
type: LocalParameter

803231
name: Scaffold_MAPK-P_MEK-PP_RAF-P
initial concentration: NaN
has only substance units: true
boundary condition: false
has part: Q05116
has part: P26696
type: Species
constant: false
in compartment: 801486
initial amount: 0.0
has part: P09560

http://identifiers.org/biomodels.db/BIOMD0000000014#_7f22ac63_bebf_41f7_b725_f08ca084c0af
value: 10.0
type: LocalParameter

812935
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_2c4fd5dc_c0b0_40e2_9bce_456dbfcd7135
stoichiometry: 1.0
species: 802481
type: SpeciesReference

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stoichiometry: 1.0
species: 802121
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f7c29069_fb8d_4825_a50d_6e150bf7e297
stoichiometry: 1.0
species: 802392
type: SpeciesReference

820364
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_21380910_754e_468c_9ebd_f06a7faf694a
stoichiometry: 1.0
species: 803051
type: SpeciesReference

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stoichiometry: 1.0
species: 801761
type: SpeciesReference

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stoichiometry: 1.0
species: 802362
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bc38504d_b444_4352_a2d8_f7ba03c7de7e
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_7ecece98_f9a8_440e_8a85_b3d945b678b2
stoichiometry: 1.0
species: 803171
type: SpeciesReference

824284
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_98677388_a2c4_4f09_af11_c5d200dab46e
stoichiometry: 1.0
species: 802571
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_9e9cd862_9306_40ee_a9c3_e66738c55522
value: 0.4
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_87e46a98_b040_4ce1_b6d7_6c1a84a331e2
stoichiometry: 1.0
species: 801552
type: SpeciesReference

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stoichiometry: 1.0
species: 801612
type: SpeciesReference

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stoichiometry: 1.0
species: 803351
type: SpeciesReference

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value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_6b22c02e_54bb_4628_a307_54858a5144ee
stoichiometry: 1.0
species: 803201
type: SpeciesReference

817285
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

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stoichiometry: 1.0
species: 803261
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stoichiometry: 1.0
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value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#d89a9959_d33b_4f63_8f2a_4830b3e9283c
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 0.5
type: LocalParameter

810625
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

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value: 0.5
type: LocalParameter

814475
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

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value: 20.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#d9302fef_53c6_4667_b0ba_3cee4c389a3f
stoichiometry: 1.0
species: 801851
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stoichiometry: 1.0
species: 801851
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806215
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

802181
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.1
in compartment: 801486
name: Scaffold
type: Species

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 802812
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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type: SpeciesReference

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value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 802751
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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803441
name: Scaffold_MAPK-PP_MEK-P
boundary condition: false
initial amount: 0.0
in compartment: 801486
type: Species
has only substance units: true
initial concentration: NaN
constant: false
has part: P26696
has part: Q05116

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stoichiometry: 1.0
species: 802092
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 801731
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815315
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 803261
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816085
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

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stoichiometry: 1.0
species: 802301
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809435
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 801971
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stoichiometry: 1.0
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802931
constant: false
has only substance units: true
has part: P26696
initial amount: 0.0
boundary condition: false
in compartment: 801486
name: Scaffold_MAPK-P_RAF
initial concentration: NaN
type: Species
has part: P09560

http://identifiers.org/biomodels.db/BIOMD0000000014#_5e815645_1d01_44c3_837b_3fe98df245d1
value: 0.5
type: LocalParameter

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stoichiometry: 1.0
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value: 0.0
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 802451
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stoichiometry: 1.0
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stoichiometry: 1.0
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803111
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constant: false
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value: 0.1
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 801641
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803951
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boundary condition: false

802032
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constant: false
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stoichiometry: 1.0
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value: 0.05
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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 10.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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802301
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constant: false
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http://identifiers.org/biomodels.db/BIOMD0000000014#_3d9a6b3d_9591_4cb7_bdfd_b50524990876
value: 0.0
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stoichiometry: 1.0
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value: 0.0
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807335
is version of: GO:0051019
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name: binding of MAPK on scaffold
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value: 0.1
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value: 0.05
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stoichiometry: 1.0
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stoichiometry: 1.0
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813915
fast: false
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value: 10.0
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811745
is version of: GO:0043241
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type: Reaction

804011
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boundary condition: false
constant: false
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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810345
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value: 10.0
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809225
is version of: GO:0043241
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name: dissociation of MAPK-P from scaffold
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value: 0.5
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817355
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stoichiometry: 1.0
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value: 0.05
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value: 10.0
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value: 10.0
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stoichiometry: 1.0
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816225
is version of: GO:0043241
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805585
is version of: GO:0051019
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822044
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is version of: GO:0000185
is version of: GO:0008349
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is version of: http://identifiers.org/ec-code/2.7.11.1

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value: 0.1
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810275
is version of: GO:0051019
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802602
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809855
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value: 0.1
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820784
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815035
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822114
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is version of: GO:0031435

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811815
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814685
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name: dissociation of MEK-PP from scaffold
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809155
is version of: GO:0051019
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name: binding of MAPK-P on scaffold
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819314
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821387
is: GO:0004709
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fast: false
reversible: false
name: phosphorylation of MEK on scaffold
type: Reaction

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value: 10.0
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817705
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name: binding of RAF on scaffold
type: Reaction

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species: 802631
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stoichiometry: 1.0
species: 802991
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_25a8278a_69c0_472b_a75e_e6dbf3e7e2ae
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#dd7cfe05_af1f_43e9_b7f8_2c0e2a5a3634
stoichiometry: 1.0
species: 802631
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_008f83f8_7f41_473d_b35d_3220b2b221c2
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_21c288fd_3a0a_4c30_bad1_476948f014e0
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_84be0b46_f3f8_45d2_9a49_293312133f42
stoichiometry: 1.0
species: 802901
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ee07b275_2a6f_43d5_8c3d_afdd97908b5a
stoichiometry: 1.0
species: 803322
type: SpeciesReference

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stoichiometry: 1.0
species: 803531
type: SpeciesReference

824634
reversible: false
name: binding of RAF and RAFK
type: Reaction
is version of: REACT 996
is version of: GO:0031435
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000014#e0507907_bdcc_4f09_a74c_703fc3be7f55
stoichiometry: 1.0
species: 803621
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_84cb6cdc_f5de_4fa1_b03d_350632e86545
stoichiometry: 1.0
species: 801731
type: SpeciesReference

819945
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#f98c0588_e0fe_4e55_8746_6f365e2e128f
stoichiometry: 1.0
species: 801641
type: SpeciesReference

816785
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_72301fe2_8b82_49fd_9e4f_b7a60ccd632d
stoichiometry: 1.0
species: 801641
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_791aa060_11be_4c88_8590_0ecf81e053de
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_7c4c5f6a_6c1a_44f2_992b_ee834a358d3a
stoichiometry: 1.0
species: 802481
type: SpeciesReference

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stoichiometry: 1.0
species: 802661
type: SpeciesReference

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

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stoichiometry: 1.0
species: 801641
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802661
type: Species
constant: false
initial concentration: NaN
in compartment: 801486
has only substance units: true
has part: Q05116
has part: P09560
name: Scaffold_MAPK_MEK_RAF
initial amount: 0.0
boundary condition: false
has part: P26696

813425
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

815735
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#e4c6bbef_491a_4e56_a317_695e49ab63f8
stoichiometry: 1.0
species: 803141
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_01310d2f_062b_430c_8ed5_e3fd2b57357f
value: 0.0
type: LocalParameter

822674
type: Reaction
is version of: GO:0000185
reversible: false
is version of: http://identifiers.org/ec-code/2.7.11.1
fast: false
name: phosphorylation of RAF on scaffold

http://identifiers.org/biomodels.db/BIOMD0000000014#_8e43f9f3_6335_4895_9b63_9bde55225ac3
value: 0.1
type: LocalParameter

807125
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

804536
fast: false
name: binding of MEK and RAF-P
type: Reaction
is version of: GO:0031435
is version of: GO:0031434
reversible: false
is homolog to: REACT 143

820504
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#e331a98a_d59b_4804_b5ea_7fe65cb496bf
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_22fe2623_1dd8_4f50_a205_a7f42b6ad3d8
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ef13e07d_9f8b_476f_a326_f4e75d736dd0
stoichiometry: 1.0
species: 801671
type: SpeciesReference

813495
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_258055db_b484_4b70_8bff_a567299fc04a
stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_452fdbd8_c331_4db4_a228_7ba2106a2745
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_767e65ce_7b8a_4835_b3e5_5de05a2fd89d
stoichiometry: 1.0
species: 801851
type: SpeciesReference

803261
has part: P26696
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_MAPK-PP
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_73690fab_0eee_4df4_bb10_ac61bf81009a
stoichiometry: 1.0
species: 801761
type: SpeciesReference

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stoichiometry: 1.0
species: 803261
type: SpeciesReference

818824
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_6b7d6262_65c0_440e_b8c8_d3e8d4b5ef96
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0e60b94d_5bc7_4352_bd61_cdfa6301abb0
stoichiometry: 1.0
species: 803111
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bbedb374_7428_4b35_add6_16a3e816c540
stoichiometry: 1.0
species: 803861
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0f6d0f39_a535_47a3_ac3b_a34eb237fb01
stoichiometry: 1.0
species: 801851
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http://identifiers.org/biomodels.db/BIOMD0000000014#ab969a19_012d_4237_9807_12831313829c
stoichiometry: 1.0
species: 801821
type: SpeciesReference

814549
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

801941
has part: P09560
constant: false
name: MEK_RAF-P
initial concentration: NaN
in compartment: 801486
has only substance units: true
initial amount: 0.0
has part: Q05116
type: Species
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_0ac11cb0_e00d_4665_81c2_ab0119f660a7
stoichiometry: 1.0
species: 802211
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5070e30d_5b3e_44d5_b350_b0932d9c9dcd
stoichiometry: 1.0
species: 803322
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6f994129_834a_4c0b_8121_234b053ed799
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_145b3036_95b1_4a79_b18b_c4b43a6d137d
stoichiometry: 1.0
species: 803711
type: SpeciesReference

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stoichiometry: 1.0
species: 802901
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stoichiometry: 1.0
species: 802211
type: SpeciesReference

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stoichiometry: 1.0
species: 801821
type: SpeciesReference

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stoichiometry: 1.0
species: 803921
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_95509c6a_73c0_4ced_b497_c61a420559ee
stoichiometry: 1.0
species: 802901
type: SpeciesReference

813005
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7116701c_8faa_4861_96b8_9c743ce0da64
stoichiometry: 1.0
species: 801641
type: SpeciesReference

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stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
species: 801941
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_8fb1c6f7_e002_4706_aaba_2572c2e1f2c5
stoichiometry: 1.0
species: 802781
type: SpeciesReference

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stoichiometry: 1.0
species: 803801
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stoichiometry: 1.0
species: 801791
type: SpeciesReference

812165
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_9681866a_73c9_44bf_bff5_a4373a8e41fd
stoichiometry: 1.0
species: 802421
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stoichiometry: 1.0
species: 802781
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stoichiometry: 1.0
species: 801941
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_01f0786c_a357_4fa9_907a_509db31ea8d4
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#ad365d23_625c_4b3a_81cc_4b3c4704f591
value: 10.0
type: LocalParameter

823584
fast: false
is version of: GO:0031435
name: binding of RAF and RAFK
type: Reaction
is version of: REACT 996
reversible: false

820574
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#afac37bd_bd20_46d6_8476_157054aecfe8
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#a570909f_3393_4245_be1f_1b0c07fab1f7
stoichiometry: 1.0
species: 802991
type: SpeciesReference

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stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d22b9baa_844f_42a4_870a_be8f3a1b5851
value: 0.5
type: LocalParameter

809785
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_212f4bf4_57d6_4d28_8fda_c2286fcf2463
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#c91227ea_3a81_4519_abf7_e00f1f2d53b0
stoichiometry: 1.0
species: 801761
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_42db2c65_038f_41a7_a85e_3dd1385a4ad6
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_95c89fce_8925_4bcd_8332_1c760b4f2702
stoichiometry: 1.0
species: 803351
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d764384a_f8e9_41d7_9c34_7e5f50607518
stoichiometry: 1.0
species: 803291
type: SpeciesReference

809085
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

804118
is version of: GO:0006461
fast: false
type: Reaction
is homolog to: REACT 996
reversible: false
is version of: GO:0031435
name: binding of RAF and RAFK

http://identifiers.org/biomodels.db/BIOMD0000000014#_73d6be8a_24fd_4b09_a5b3_11080d591a93
value: 0.0
type: LocalParameter

809365
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#b9bc4c5f_148c_4b86_a069_46f5f6a8fb58
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_60119679_14f9_4709_964d_8c0e1a7c0f11
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_2a4d3cba_3411_4111_bbbf_3c446d2548de
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_620b77fc_c383_4b5b_a1f4_b1a1d7553f27
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#cc65062e_8a8c_4e33_ae00_f132b4d4af19
stoichiometry: 1.0
species: 801761
type: SpeciesReference

818195
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

812025
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#d89f9260_d394_4b68_8b5f_8485e82518ae
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_46f1bae1_9200_42f0_87cd_17e21f1b72e0
stoichiometry: 1.0
species: 802541
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f0efb26e_03c1_40bd_bcfe_a44bbb2f8d02
stoichiometry: 1.0
species: 803261
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d4b114c0_8f8a_4fe0_ba4c_1a04a7400a3a
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_35d6165e_04bb_4e3c_9da3_fe699ffdbb84
stoichiometry: 1.0
species: 802812
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_73b3742b_1c1f_4f75_a7d6_7f11b5b850f9
value: 0.5
type: LocalParameter

801731
is version of: Q05116
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.2
in compartment: 801486
name: MEK
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#ff8a80ec_7238_47b8_ae3c_76dc816bb55b
stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 802602
type: SpeciesReference

802751
boundary condition: false
name: Scaffold_MAPK_MEK-P_RAF
in compartment: 801486
type: Species
has part: P26696
initial concentration: NaN
initial amount: 0.0
has only substance units: true
constant: false
has part: P09560
has part: Q05116

http://identifiers.org/biomodels.db/BIOMD0000000014#_2cf60c2b_e922_46f6_b81e_9c64a14760ca
stoichiometry: 1.0
species: 802392
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stoichiometry: 1.0
species: 802241
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_59529a63_55fc_4328_b4da_3b461e6559bb
value: 0.0
type: LocalParameter

821237
is: GO:0000186
fast: false
type: Reaction
name: phosphorylation of MEK-P on scaffold
is: GO:0004709
reversible: false
is: http://identifiers.org/ec-code/2.7.1.37

http://identifiers.org/biomodels.db/BIOMD0000000014#_05341f52_6aa4_4b41_b1e2_f566e2b44db1
stoichiometry: 1.0
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stoichiometry: 1.0
species: 803021
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_338e9aa9_27f5_401e_957f_6de2c9159a6b
value: 0.05
type: LocalParameter

803561
initial amount: 0.0
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has part: P09560
name: Scaffold_MAPK-PP_MEK-PP_RAF
has only substance units: true
has part: P26696
in compartment: 801486
initial concentration: NaN
constant: false
type: Species
boundary condition: false

801911
initial concentration: NaN
has part: Q05116
name: MAPK-P_MEK-PP
boundary condition: false
has only substance units: true
initial amount: 0.0
in compartment: 801486
type: Species
has part: P26696
constant: false

http://identifiers.org/biomodels.db/BIOMD0000000014#f5a16eca_c4d5_47c9_a398_42fb99710d7e
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#a3f8e8b7_e98b_4a5a_aba9_230364fd0636
stoichiometry: 1.0
species: 802211
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http://identifiers.org/biomodels.db/BIOMD0000000014#_53459ff2_850d_48f5_ac48_28675f0d007d
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_54f5cc7e_7e98_44b0_9906_89d60fab0123
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_43371e9a_4d8e_4db4_bf51_436d8cd63e67
stoichiometry: 1.0
species: 803531
type: SpeciesReference

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stoichiometry: 1.0
species: 801791
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_314da964_6f68_441c_8777_b1e317bce397
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#a5925f77_742e_455f_a901_afd8ac88009d
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f7429da5_357b_4995_9796_0e93dbd06ebb
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_3a085397_088c_4585_a76a_4027f8d04aef
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_2ce1b1b1_1a1e_48aa_a2ec_8258258b3f48
stoichiometry: 1.0
species: 801851
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http://identifiers.org/biomodels.db/BIOMD0000000014#_01b39a28_f9f3_42e6_a387_1b2c33088721
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_50d6383d_97a3_4378_b970_846acf76d524
stoichiometry: 1.0
species: 802332
type: SpeciesReference

801486
is version of: GO:0005737
constant: true
size: 1.0
spatial dimensions: 3.0
type: Compartment

http://identifiers.org/biomodels.db/BIOMD0000000014#eef299d5_3f19_4da7_ac7b_a28d0b0d37c2
stoichiometry: 1.0
species: 801641
type: SpeciesReference

808805
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_47d074d6_8d13_49f8_8156_ff2ac0da78f9
stoichiometry: 1.0
species: 803141
type: SpeciesReference

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stoichiometry: 1.0
species: 802451
type: SpeciesReference

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stoichiometry: 1.0
species: 801791
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_86e73be1_3f0b_46c0_a913_63f9ccedf403
value: 0.1
type: LocalParameter

820295
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_92a028b0_3ba2_4cca_8015_400ef8d251c9
stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

818475
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_10a3f62c_b35f_4b47_bae0_6f65180ed120
stoichiometry: 1.0
species: 801761
type: SpeciesReference

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stoichiometry: 1.0
species: 802271
type: SpeciesReference

813845
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_06afe30c_fdc6_4277_b58d_098f57111221
stoichiometry: 1.0
species: 802541
type: SpeciesReference

808735
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#e74b803a_d8b9_44bc_9fb6_d7fecbfb92b9
value: 0.4
type: LocalParameter

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stoichiometry: 1.0
species: 803291
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cab9db93_badc_4d14_83a3_6febfb231e4b
value: 0.1
type: LocalParameter

821437
reversible: false
is: GO:0000186
type: Reaction
name: phosphorylation of MEK-P on scaffold
fast: false
is: http://identifiers.org/ec-code/2.7.1.37
is: GO:0004709

http://identifiers.org/biomodels.db/BIOMD0000000014#_9746080b_3f65_48b3_9fa4_729f42ac0d0c
stoichiometry: 1.0
species: 801641
type: SpeciesReference

804255
fast: false
type: Reaction
reversible: false
is version of: GO:0000185
is version of: http://identifiers.org/ec-code/2.7.11.1
name: phosphorylation of RAF
is version of: GO:0008349

http://identifiers.org/biomodels.db/BIOMD0000000014#a9d95340_5dcc_40ec_9363_592024aa146c
stoichiometry: 1.0
species: 801582
type: SpeciesReference

803411
type: Species
has part: P26696
constant: false
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has part: Q05116
in compartment: 801486
has only substance units: true
name: Scaffold_MAPK-PP_MEK_RAF-P
boundary condition: false
initial amount: 0.0
initial concentration: NaN

http://identifiers.org/biomodels.db/BIOMD0000000014#_799f8b57_4186_47bf_bf79_e53376bf8881
stoichiometry: 1.0
species: 802871
type: SpeciesReference

808665
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_8d6de291_1492_4761_8a50_5f9150887fc4
stoichiometry: 1.0
species: 801671
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_2d2309d4_d52e_4591_84e5_5118caf35606
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 802271
type: SpeciesReference

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stoichiometry: 1.0
species: 801701
type: SpeciesReference

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stoichiometry: 1.0
species: 803141
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817915
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#bc81ca28_e943_4ed3_acf6_5031abcc706a
stoichiometry: 1.0
species: 803231
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cfa9ecc3_f1d0_4f3b_8447_18d25cc6fda4
value: 10.0
type: LocalParameter

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stoichiometry: 1.0
species: 802691
type: SpeciesReference

802812
has part: Q05116
boundary condition: false
initial concentration: NaN
in compartment: 801486
constant: false
has part: P26696
name: Scaffold_MAPK_MEK-PP
initial amount: 0.0
type: Species
has only substance units: true

http://identifiers.org/biomodels.db/BIOMD0000000014#_3f5d3966_f5c0_4638_8639_d296fa7a6575
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#e3ec5b15_20a1_42b9_a54d_033de6ebeebb
stoichiometry: 1.0
species: 801761
type: SpeciesReference

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stoichiometry: 1.0
species: 803951
type: SpeciesReference

812585
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_3b7dc33a_e248_4d23_a814_574415edceb6
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#c76f4405_4ce6_44e1_8e3a_844dea4237cf
value: 3.3
type: LocalParameter

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stoichiometry: 1.0
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type: SpeciesReference

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stoichiometry: 1.0
species: 801612
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stoichiometry: 1.0
species: 802241
type: SpeciesReference

801882
has only substance units: true
initial amount: 0.0
in compartment: 801486
boundary condition: false
constant: false
initial concentration: NaN
type: Species
name: MAPK_MEK-PP
has part: Q05116
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http://identifiers.org/biomodels.db/BIOMD0000000014#_8eeba172_c127_4891_8f36_0fbbda0de051
stoichiometry: 1.0
species: 802151
type: SpeciesReference

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stoichiometry: 1.0
species: 801761
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824704
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

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stoichiometry: 1.0
species: 803981
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stoichiometry: 1.0
species: 802631
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stoichiometry: 1.0
species: 803561
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stoichiometry: 1.0
species: 802781
type: SpeciesReference

821764
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_3c8e6a2c_9cb2_41b9_a335_a7fb55aed4b9
stoichiometry: 1.0
species: 801641
type: SpeciesReference

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stoichiometry: 1.0
species: 802812
type: SpeciesReference

805801
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P and MEK-PP
type: Reaction

809505
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

807057
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#f498afae_9582_48b1_ae03_68c2150ee829
stoichiometry: 1.0
species: 801641
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 802842
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_4230c38c_b2d7_44d4_83c2_59da45786b79
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_615d37ed_8b71_4195_afcd_c745929bd3ba
stoichiometry: 1.0
species: 803141
type: SpeciesReference

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stoichiometry: 1.0
species: 803141
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817774
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

807965
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

824218
is version of: REACT 996
is version of: GO:0031435
name: binding of RAF and RAFK
reversible: false
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000014#ce9b676c_ecc7_4b8b_9a16_6d6a5fc967e3
value: 0.1
type: LocalParameter

803171
in compartment: 801486
initial amount: 0.0
constant: false
boundary condition: false
initial concentration: NaN
name: Scaffold_MAPK-P_MEK-PP
type: Species
has part: Q05116
has only substance units: true
has part: P26696

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stoichiometry: 1.0
species: 803711
type: SpeciesReference

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stoichiometry: 1.0
species: 802332
type: SpeciesReference

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stoichiometry: 1.0
species: 804071
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808876
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_493104fc_2179_4293_a7fc_84a7bd628da8
value: 0.0
type: LocalParameter

819874
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_06213661_589b_430a_b717_13b25dfeb1ad
stoichiometry: 1.0
species: 803111
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stoichiometry: 1.0
species: 802451
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stoichiometry: 1.0
species: 802241
type: SpeciesReference

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stoichiometry: 1.0
species: 803411
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802211
has part: P09560
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_RAF
type: Species

818264
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_6aa27ed5_1970_4c43_8393_f9bea69b9ef9
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_85926081_e0b5_465e_b7e8_d2d0aa676cf7
value: 0.5
type: LocalParameter

810835
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_9b7300a2_5465_4566_a9a5_4407848bedf7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#ff3c4273_5f0b_43ac_9fe7_3b9fcd4ce9d2
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#e37f04a1_4114_4166_89fa_47370b020039
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
species: 802571
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stoichiometry: 1.0
species: 802421
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

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stoichiometry: 1.0
species: 803741
type: SpeciesReference

823654
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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809295
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

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stoichiometry: 1.0
species: 803891
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stoichiometry: 1.0
species: 803561
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value: 0.42
type: LocalParameter

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value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_74363c4b_9b15_45c5_ad2c_baf4a3b22209
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 803831
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805095
name: phosphorylation of MEK-P
is version of: GO:0000186
is version of: GO:0006468
is version of: http://identifiers.org/ec-code/2.7.1.37
is version of: GO:0004709
reversible: false
fast: false
is homolog to: REACT 614
type: Reaction

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stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
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stoichiometry: 1.0
species: 803021
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 802511
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810555
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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810485
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_052002ed_b32e_4562_940e_76da21231859
value: 0.0
type: LocalParameter

804605
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK_RAF-P
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_98f57887_0e7a_42e6_825e_4cdb914e78f4
stoichiometry: 1.0
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stoichiometry: 1.0
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803801
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in compartment: 801486
name: Scaffold_MAPK_MEK-P_RAF
has part: Q05116
has only substance units: true
boundary condition: false
constant: false
has part: P26696
initial concentration: NaN
type: Species
initial amount: 0.0

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stoichiometry: 1.0
species: 802301
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
species: 802602
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stoichiometry: 1.0
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value: 0.05
type: LocalParameter

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stoichiometry: 1.0
species: 803171
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stoichiometry: 1.0
species: 801761
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806565
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_0303fa34_f5e9_42be_81c0_818d29d6748f
value: 100.0
type: LocalParameter

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stoichiometry: 1.0
species: 802842
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802332
boundary condition: false
constant: false
has only substance units: true
has part: Q05116
initial concentration: NaN
initial amount: 0.0
has part: P09560
type: Species
name: Scaffold_MEK_RAF-P
in compartment: 801486

http://identifiers.org/biomodels.db/BIOMD0000000014#_5f89a898_3e38_44bb_94c8_8cf24432909c
stoichiometry: 1.0
species: 801701
type: SpeciesReference

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stoichiometry: 1.0
species: 802931
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5710fae0_a04b_46ae_a4bb_3764f6ff6def
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_980f5607_d327_47f5_bd96_8e78ab08ca1c
stoichiometry: 1.0
species: 802332
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d0b1e414_de8a_431a_99a3_40e6e3c72874
stoichiometry: 1.0
species: 802301
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3e656fc8_60c3_4db9_99ac_57aac597a29f
stoichiometry: 1.0
species: 802301
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_16a8792a_ca7f_4b86_82ae_09a8ee49bf08
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_40fe3dc9_e8e5_4511_9366_939ba2941a39
stoichiometry: 1.0
species: 801821
type: SpeciesReference

810765
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

819104
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_96a2d9bd_4966_436f_8528_2c7cd6736210
stoichiometry: 1.0
species: 802271
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a4dd9a4e_74b0_4536_bd93_1c57f66acceb
stoichiometry: 1.0
species: 802812
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#dcbf0b94_069d_46ff_a86e_c2122714542c
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_50b5af39_37fe_47ed_9ac2_187d10925c41
stoichiometry: 1.0
species: 803351
type: SpeciesReference

824564
name: phosphorylation of RAF on scaffold
fast: false
reversible: false
is version of: GO:0000185
is version of: GO:0008349
is version of: http://identifiers.org/ec-code/2.7.11.1
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_6945bae4_ebb8_4366_8bfe_dc6b2fc52be7
stoichiometry: 1.0
species: 803291
type: SpeciesReference

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stoichiometry: 1.0
species: 803291
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_119ee771_c19f_4e32_b6fa_cd4e3413bf35
value: 3.3
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#ad73e01f_a951_4c6d_90ca_796ed2602105
value: 0.0
type: LocalParameter

817215
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_0ce756fd_fb05_480f_96a2_cd15a70bedc4
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_1bb44634_790e_4662_abb3_697a3a01e5e0
stoichiometry: 1.0
species: 804041
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bfa62de2_50d8_4b23_932b_7a45fc9d3e73
stoichiometry: 1.0
species: 803382
type: SpeciesReference

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stoichiometry: 1.0
species: 803051
type: SpeciesReference

821137
reversible: false
is: GO:0004709
is: http://identifiers.org/ec-code/2.7.1.37
type: Reaction
fast: false
name: phosphorylation of MEK-P on scaffold
is: GO:0000186

815595
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_4725d454_0e7d_4f80_be80_a9fbb960965d
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_90d7e3c6_e0b4_49ff_8c6d_588585c2dd64
stoichiometry: 1.0
species: 802362
type: SpeciesReference

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stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_86a4e98a_c0aa_4e28_aeb7_c27c4f3e058f
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_09e332ee_8e26_44d8_8b6c_0fd1dcff5595
value: 100.0
type: LocalParameter

821487
is version of: REACT 996
name: binding of RAF and RAFK
reversible: false
fast: false
type: Reaction
is version of: GO:0031435

http://identifiers.org/biomodels.db/BIOMD0000000014#_39c458f7_d30b_4b1b_a7b2_096a0e9afcca
stoichiometry: 1.0
species: 802901
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#dc394c10_9fca_40ff_8355_c71488d38415
stoichiometry: 1.0
species: 803591
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_40dca9f8_7c5c_422f_9e65_189c1e5b9828
stoichiometry: 1.0
species: 803951
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_457f4162_57cc_4c1b_a052_b8235a03889c
stoichiometry: 1.0
species: 802511
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f53e5ebf_05a7_475a_929e_57f5cbf12f80
stoichiometry: 1.0
species: 803051
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_79b40cbc_96f2_48af_8c4a_10de66bb4a1d
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_6c38a985_bf58_45be_9600_33699fac2b95
stoichiometry: 1.0
species: 801701
type: SpeciesReference

824074
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_1a49f771_f4c5_46b8_9909_26ecd8e3aacc
stoichiometry: 1.0
species: 802241
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5a8358db_b35b_4835_925c_2c85ef0cbb93
stoichiometry: 1.0
species: 803291
type: SpeciesReference

802061
has part: Q05116
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: MEK-P_MEKPase
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#dfb8cc81_176c_4dc2_85ff_af6a95e89836
stoichiometry: 1.0
species: 802961
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#daca19e8_1d05_4159_b93c_2d1df72c6f2a
stoichiometry: 1.0
species: 802631
type: SpeciesReference

805165
is version of: GO:0031434
fast: false
reversible: false
name: binding of MEK-PP and MEK phosphatase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_4b4d737c_9b65_401d_a024_bac5e96348c8
stoichiometry: 1.0
species: 802901
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7312be0c_a4f5_44e9_8c7d_0a83c0be5fde
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b6c40349_18cb_4129_ac71_ddd1751d5c64
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_283870b2_51e7_4912_a180_0f99724b9e72
stoichiometry: 1.0
species: 803891
type: SpeciesReference

812235
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

807895
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#e8e2bfac_0e5b_4f26_b593_39026fb9d45b
stoichiometry: 1.0
species: 801582
type: SpeciesReference

822814
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

815245
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

820644
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#bb6b5d2b_a7da_453c_af6c_aa17d93d20cf
value: 100.0
type: LocalParameter

821287
is: GO:0004709
is: http://identifiers.org/ec-code/2.7.1.37
fast: false
reversible: false
name: phosphorylation of MEK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#f7a12826_3cf9_4359_a15b_3bea743057eb
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_4130f069_f9ae_4343_8b86_0c330e0f43eb
stoichiometry: 1.0
species: 802211
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a2854bfb_ba61_4b4a_99ee_bf03c87c593f
stoichiometry: 1.0
species: 802931
type: SpeciesReference

815665
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_09a2208f_c609_4d75_ae04_fed088fec173
stoichiometry: 1.0
species: 802181
type: SpeciesReference

820937
reversible: false
type: Reaction
name: phosphorylation of MAPK-P on scaffold
fast: false
is: GO:0004708
is: http://identifiers.org/ec-code/2.7.1.37
is: GO:0000187

http://identifiers.org/biomodels.db/BIOMD0000000014#_81156d22_1685_4e8a_b97b_c49b95ddc009
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a9744921_1ea5_49fe_be40_6a23f36aa930
stoichiometry: 1.0
species: 802842
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d1042ddb_887f_4d2a_9a05_8f521176e476
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#f1d4c0bb_6a6a_42af_941b_fb2fc2f6e050
stoichiometry: 1.0
species: 802181
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_47f9fac3_011e_46f6_9b8a_ca0faef933b1
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ddc87532_20a4_4b04_914b_1d8fcef60c29
stoichiometry: 1.0
species: 802362
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f3533a5b_9f3b_451d_bbc7_dcf13291c9a3
stoichiometry: 1.0
species: 803382
type: SpeciesReference

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stoichiometry: 1.0
species: 801701
type: SpeciesReference

802481
constant: false
has part: P09560
type: Species
name: Scaffold_MEK-PP_RAF
initial concentration: NaN
has part: Q05116
in compartment: 801486
has only substance units: true
initial amount: 0.0
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_94761f4e_a913_48c0_9aa2_4b53345513e0
stoichiometry: 1.0
species: 802961
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ddb2f875_a499_41bb_98fa_99434b265ff6
stoichiometry: 1.0
species: 803201
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a0b8c9cc_0570_4f5d_a0f6_fb1539166724
stoichiometry: 1.0
species: 803021
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cf7260c7_c650_4930_83eb_3122e01e971e
stoichiometry: 1.0
species: 801582
type: SpeciesReference

812655
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_31bc2bfa_6832_498c_8782_f02b282ef490
stoichiometry: 1.0
species: 802571
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0bfb90ce_ea00_4853_947c_6b22d7d80125
stoichiometry: 1.0
species: 804011
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_2f5cda82_ec93_41d2_8457_d908ead71175
stoichiometry: 1.0
species: 803921
type: SpeciesReference

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stoichiometry: 1.0
species: 801582
type: SpeciesReference

820015
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

819034
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7447ad90_3e42_4236_81ca_b9685d55b994
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#e75182a0_8440_480a_8b4b_dc73676bea78
stoichiometry: 1.0
species: 802871
type: SpeciesReference

803861
initial amount: 0.0
has only substance units: true
type: Species
boundary condition: false
in compartment: 801486
name: Scaffold_MAPK-P_RAF
has part: P26696
initial concentration: NaN
has part: P09560
constant: false

816855
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#d9215240_a7f5_44ce_8d11_cea9c22e96f8
value: 0.0
type: LocalParameter

806355
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

813635
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#fd45760c_a592_44a8_aedf_e4561e4b57de
stoichiometry: 1.0
species: 803561
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5d8451ff_6bd5_48ea_b8ea_d904255a9c32
value: 20.0
type: LocalParameter

817495
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#c29cacb6_da39_468b_b84d_dbe231561fae
stoichiometry: 1.0
species: 802421
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3ce03063_0ae4_40e3_98bc_36b1b18c05e0
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_804ddae5_478c_49cd_9fd0_9622bf2700dc
stoichiometry: 1.0
species: 802451
type: SpeciesReference

816017
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_985d4a2d_f011_4fe3_b136_8a7dd88a66d8
stoichiometry: 1.0
species: 802392
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_1e278601_b4e8_4024_bb5b_5f4852dcddcb
stoichiometry: 1.0
species: 802931
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f804bee4_eb8c_4803_855c_89554ac9ed94
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_9908dffc_436c_4054_a7ad_d6675de4d3ab
stoichiometry: 1.0
species: 801761
type: SpeciesReference

804325
is version of: GO:0031435
fast: false
reversible: false
name: binding of RAF-P and RAF phosphatase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_07483a6a_0363_4652_b5c9_ba6064130fdd
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#b05c35b8_d314_4912_a624_5da535ad52db
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#cd23beca_50ae_4190_a463_72bfcdde284a
stoichiometry: 1.0
species: 802812
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ad5f783d_3f36_4565_9626_49545fbbe91d
stoichiometry: 1.0
species: 802511
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d42cd4c6_dbd3_4a5c_8214_7afed8226ba0
stoichiometry: 1.0
species: 802392
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bf871c39_c9e3_43ee_80c7_8c863f0cca59
stoichiometry: 1.0
species: 802421
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7e98ca2c_2959_4af2_87d1_cd47a11a6e1c
stoichiometry: 1.0
species: 802481
type: SpeciesReference

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stoichiometry: 1.0
species: 803051
type: SpeciesReference

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stoichiometry: 1.0
species: 802751
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_58dafeb0_db38_4911_8338_e7b9480e61c7
stoichiometry: 1.0
species: 802421
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_78e54b0d_9beb_41bf_893e_31d538105f38
value: 0.0
type: LocalParameter

824144
is version of: http://identifiers.org/ec-code/2.7.11.1
reversible: false
type: Reaction
is version of: GO:0000185
fast: false
name: phosphorylation of RAF on scaffold
is version of: GO:0008349

802781
has part: P26696
initial concentration: NaN
boundary condition: false
has part: Q05116
in compartment: 801486
has part: P09560
name: Scaffold_MAPK_MEK-P_RAF-P
has only substance units: true
initial amount: 0.0
constant: false
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_5c7e2361_6ac3_42eb_974f_7a150cdb96b7
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_58cc39be_57ae_4182_a37f_a225cbc56baf
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_81b2e5cd_e779_4185_90a6_866e1f799fca
stoichiometry: 1.0
species: 801821
type: SpeciesReference

824354
is version of: GO:0000185
name: phosphorylation of RAF on scaffold
type: Reaction
is version of: GO:0008349
reversible: false
fast: false
is version of: http://identifiers.org/ec-code/2.7.11.1

http://identifiers.org/biomodels.db/BIOMD0000000014#_21f59a08_f6a4_4aee_9c87_4c953563bea7
value: 0.05
type: LocalParameter

819526
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#beeba18d_a070_4347_a37e_4b7d54b32e4d
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0bebdb49_cc8f_4380_9f06_6af15bfa466f
stoichiometry: 1.0
species: 803201
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f71329f1_fef0_40d2_8988_c6f3a740a97d
stoichiometry: 1.0
species: 802241
type: SpeciesReference

812865
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

811605
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

803921
initial amount: 0.0
constant: false
has only substance units: true
in compartment: 801486
has part: P09560
type: Species
has part: Q05116
initial concentration: NaN
has part: P26696
name: Scaffold_MAPK-P_MEK-P_RAF
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_3de57e90_7e3d_476c_9a74_00ec08a1ec23
stoichiometry: 1.0
species: 803051
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b017813c_4c3c_4258_aa7c_d0a5fadbd23a
value: 0.5
type: LocalParameter

803711
name: Scaffold_MEK-PP_RAF
type: Species
has part: P09560
initial concentration: NaN
in compartment: 801486
boundary condition: false
has only substance units: true
initial amount: 0.0
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constant: false

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stoichiometry: 1.0
species: 802151
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d614eae0_8689_40be_a42b_51de462e9104
value: 10.0
type: LocalParameter

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

818334
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_6fdeb866_e301_40e3_9941_fd84701e15cd
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_329dbddd_bbbe_456a_a150_80c35fc482aa
stoichiometry: 1.0
species: 802991
type: SpeciesReference

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

820837
is: GO:0004708
is: http://identifiers.org/ec-code/2.7.1.37
fast: false
reversible: false
name: phosphorylation of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#a233ee9a_8953_4105_b2fd_9fac9043fbdb
stoichiometry: 1.0
species: 803831
type: SpeciesReference

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stoichiometry: 1.0
species: 801791
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stoichiometry: 1.0
species: 803351
type: SpeciesReference

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stoichiometry: 1.0
species: 801821
type: SpeciesReference

802151
has part: P09560
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: RAF-P_RAFPase
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#fda9c177_d23d_40df_8ad3_859669faa90f
stoichiometry: 1.0
species: 801851
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809015
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#d663a74e_6bdf_4145_ae36_6f5001242343
stoichiometry: 1.0
species: 802691
type: SpeciesReference

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value: 10.0
type: LocalParameter

803681
constant: false
has only substance units: true
boundary condition: false
name: Scaffold_MEK-P_RAF
has part: Q05116
has part: P09560
initial amount: 0.0
initial concentration: NaN
in compartment: 801486
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_4b46e09b_1c37_4c83_a74e_b550e6698cde
value: 0.1
type: LocalParameter

818894
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7150bd9c_06bc_40df_9c84_57aca0e1c0ca
stoichiometry: 1.0
species: 802181
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_1afecfb4_21b6_46f5_8a6e_703970273cc0
value: 0.8
type: LocalParameter

806075
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP_MAPKPase
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_0e31247c_d0f9_4f20_9e00_5d9ed08e2d1b
stoichiometry: 1.0
species: 803141
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stoichiometry: 1.0
species: 803051
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_064d6461_2590_4e6e_9cb5_6ba1505474dc
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_1c925536_8d71_4ff9_86e0_300fc51daa71
stoichiometry: 1.0
species: 801701
type: SpeciesReference

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stoichiometry: 1.0
species: 801761
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stoichiometry: 1.0
species: 802211
type: SpeciesReference

816715
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_8fba0b64_cd76_4ece_85b0_58b865a21e44
value: 10.0
type: LocalParameter

820226
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_54b6e67c_d3fc_4206_ad36_29ae15e5103c
stoichiometry: 1.0
species: 801821
type: SpeciesReference

808105
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

821694
name: binding of RAF and RAFK
type: Reaction
is version of: REACT 996
fast: false
reversible: false
is version of: GO:0031435

http://identifiers.org/biomodels.db/BIOMD0000000014#fc7ddf92_b2e0_4e47_a67b_495e29bb0b18
stoichiometry: 1.0
species: 802631
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0193843c_55e7_428c_a8dd_baf911fed19b
value: 0.1
type: LocalParameter

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stoichiometry: 1.0
species: 802392
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stoichiometry: 1.0
species: 802301
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stoichiometry: 1.0
species: 801701
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813705
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_45e61e4f_0b0a_4828_a38b_207cb3ce8f14
stoichiometry: 1.0
species: 803111
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stoichiometry: 1.0
species: 802511
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812095
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_98bc7de3_c114_43ae_a877_4516b049fb92
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#c093c5be_2cf6_43bc_ac69_4ce573ba4482
stoichiometry: 1.0
species: 801791
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stoichiometry: 1.0
species: 803891
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_44065a05_b5b5_48ec_bb68_bbc6040116ba
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_5f9fb942_4fb8_4a60_aae8_9324f3d0bd66
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_2bbea285_0b56_4590_915b_6ded96fe3b58
stoichiometry: 1.0
species: 802781
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 0.1
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http://identifiers.org/biomodels.db/BIOMD0000000014#_25958b9e_8e6b_485b_9eb7_fecdeb4c45ab
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#adae9e6d_217a_4321_888f_d7523402f6a7
value: 0.05
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http://identifiers.org/biomodels.db/BIOMD0000000014#_01f0869c_3025_4d62_8032_4c7217fb6752
stoichiometry: 1.0
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http://identifiers.org/biomodels.db/BIOMD0000000014#ac517b37_85af_4b4b_9036_8ab4ee68418d
value: 0.0
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801612
constant: false
boundary condition: false
has only substance units: true
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name: RAF phosphatase
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_797fddcf_ae8e_4182_bc83_837ba03298f8
value: 0.05
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stoichiometry: 1.0
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stoichiometry: 1.0
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http://identifiers.org/biomodels.db/BIOMD0000000014#_04b5ee9e_c07e_4ad8_8139_067ed5ad4264
value: 0.1
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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818125
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_2fcf83dc_2193_4fd2_a53b_f2f493e35ea0
value: 0.05
type: LocalParameter

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stoichiometry: 1.0
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value: 0.05
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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811466
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

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stoichiometry: 1.0
species: 803322
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stoichiometry: 1.0
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stoichiometry: 1.0
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814125
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

822884
fast: false
name: phosphorylation of RAF on scaffold
is version of: GO:0008349
reversible: false
type: Reaction
is version of: GO:0000185
is version of: http://identifiers.org/ec-code/2.7.11.1

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_20b1584f_96e1_4672_9e8c_db904743f443
stoichiometry: 1.0
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stoichiometry: 1.0
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811045
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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value: 0.5
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809995
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
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http://identifiers.org/biomodels.db/BIOMD0000000014#bde0e00e_e02b_4724_82ef_9bb16870f89a
value: 0.0
type: LocalParameter

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stoichiometry: 1.0
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stoichiometry: 1.0
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stoichiometry: 1.0
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W3 CDTF: Fri Feb 25 23:43:21 GMT 2005

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stoichiometry: 1.0
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value: 10.0
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value: 10.0
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value: 0.0
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804041
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has part: P26696
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807755
is version of: GO:0051019
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805235
is version of: GO:0043241
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reversible: false
name: dissociation of MEK-PP_MEKPase
type: Reaction

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stoichiometry: 1.0
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806705
is version of: GO:0043241
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name: dissociation of MAPK from scaffold
type: Reaction

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stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7c881e18_a15f_43c6_8c32_94bbcd8052c7
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#dd4f8ae3_fd74_47f1_aeb2_aaf0be10a1c7
stoichiometry: 1.0
species: 804071
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#beee9f19_eb1b_4731_ae7f_9fcc41af2594
stoichiometry: 1.0
species: 803411
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7dcd2fec_4237_4a9d_b3bb_c0b9313dcc59
stoichiometry: 1.0
species: 802661
type: SpeciesReference

810695
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#d8981b4b_58bf_4f35_bc41_4f74223e711b
stoichiometry: 1.0
species: 801671
type: SpeciesReference

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stoichiometry: 1.0
species: 801671
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_410f6938_54cb_4a15_8d64_82aeefd2426d
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#f844b073_c023_4e11_a1a5_20d8394a3c2d
stoichiometry: 1.0
species: 802541
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_24097238_35ad_421e_8dc7_0fd4ce66ea15
stoichiometry: 1.0
species: 803082
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3968ccf4_b449_495a_a5bc_e050098c3542
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_42b000fc_b27b_4152_93dc_d801c349853a
stoichiometry: 1.0
species: 803082
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5dcd8547_7a98_4a08_b296_476c608f60fb
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_09acdddd_c108_4dfe_94cf_537fc24a7b8f
stoichiometry: 1.0
species: 803351
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_431d7c91_82b0_4dae_90e5_e0fc647caadc
stoichiometry: 1.0
species: 801821
type: SpeciesReference

807685
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#ddd6275f_d870_432c_ac22_f8af215471d6
value: 0.05
type: LocalParameter

824424
name: binding of RAF and RAFK
reversible: false
is version of: REACT 996
is version of: GO:0031435
fast: false
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#acbc9760_9d3a_4e93_a249_99d9856e2e98
stoichiometry: 1.0
species: 802001
type: SpeciesReference

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stoichiometry: 1.0
species: 803441
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bc1ee302_b303_4872_9ba6_fd102f2489a4
stoichiometry: 1.0
species: 802362
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0f3bd9d4_27f4_4124_8768_d4212564f196
stoichiometry: 1.0
species: 802541
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7dac58a6_356a_42aa_a156_354fd4b7660e
stoichiometry: 1.0
species: 802871
type: SpeciesReference

815175
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_9882ea54_0a52_4e8e_becf_a9cd8fe42123
stoichiometry: 1.0
species: 803141
type: SpeciesReference

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stoichiometry: 1.0
species: 801552
type: SpeciesReference

817985
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_82787690_1cbd_4383_bd76_a42e7d8f2174
value: 0.1
type: LocalParameter

819246
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

824496
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

803891
constant: false
name: Scaffold_MAPK-P_MEK_RAF
initial concentration: NaN
has part: Q05116
has only substance units: true
boundary condition: false
has part: P09560
has part: P26696
type: Species
initial amount: 0.0
in compartment: 801486

http://identifiers.org/biomodels.db/BIOMD0000000014#_0029c124_ef1d_477e_adf9_685d65940a42
stoichiometry: 1.0
species: 801851
type: SpeciesReference

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stoichiometry: 1.0
species: 802842
type: SpeciesReference

806285
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

803531
in compartment: 801486
has part: Q05116
initial concentration: NaN
type: Species
boundary condition: false
initial amount: 0.0
has only substance units: true
constant: false
has part: P26696
name: Scaffold_MAPK-PP_MEK-PP

http://identifiers.org/biomodels.db/BIOMD0000000014#_9bfa8406_ad80_4927_b53d_12360a90f236
stoichiometry: 1.0
species: 801552
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0ac8c512_4abf_4a4e_814d_9958df596d6b
stoichiometry: 1.0
species: 801882
type: SpeciesReference

808525
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

802541
has part: P26696
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_MAPK
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_804ce694_4355_4eca_b066_b0ea94af9282
stoichiometry: 1.0
species: 802451
type: SpeciesReference

801552
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.2
in compartment: 801486
name: MEK phosphatase
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_0f28f920_9fb1_44d5_9aff_ec77c6416c82
stoichiometry: 1.0
species: 802481
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_49cbe681_e283_4e38_a95e_b6505c6da2c9
value: 0.05
type: LocalParameter

823444
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_0ac7a6a2_5d5e_4f51_a961_6b9427147fa3
stoichiometry: 1.0
species: 802481
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_36fcaba9_809d_4815_a8de_61a59e0eb2a3
stoichiometry: 1.0
species: 801731
type: SpeciesReference

813985
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_988d6bcf_513c_4ba8_ac44_e80fa63939d1
stoichiometry: 1.0
species: 804041
type: SpeciesReference

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stoichiometry: 1.0
species: 803531
type: SpeciesReference

806915
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_6d9f2705_48c6_403c_8354_72e7dabda86f
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#f73a2364_67e6_4f5c_9e91_3e5eda919638
value: 0.05
type: LocalParameter

815875
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#f6b322a3_3b34_410b_bdd6_a28722e9b095
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_9851be0a_3e30_4926_9f06_5a3e55bba426
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_007e9cd6_a0e3_4f55_b6e4_088ac0bc0801
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_52499450_3c00_452e_81e0_0978f20a3a77
value: 0.05
type: LocalParameter

818755
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_6702de02_7a96_470f_ad51_cc599710dd55
stoichiometry: 1.0
species: 803382
type: SpeciesReference

822324
reversible: false
is version of: GO:0031435
name: binding of RAF and RAFK
fast: false
is version of: REACT 996
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_8972fe27_c4fa_451f_b174_dab7598ac71a
stoichiometry: 1.0
species: 802721
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_9b44d5b7_f027_425f_bd09_9ac5eafa8bcd
stoichiometry: 1.0
species: 803382
type: SpeciesReference

820434
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#dc95af44_7661_412d_b6ab_d2ba83cd5126
stoichiometry: 1.0
species: 802842
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b7f3d980_8b8a_4a23_9c54_284e66ad0696
stoichiometry: 1.0
species: 801761
type: SpeciesReference

813285
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7e9dd3e1_a71e_4abc_b45c_5a733102c3c8
stoichiometry: 1.0
species: 801821
type: SpeciesReference

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_42b4eca6_6ae5_47a5_9183_f70937b558e3
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#c9de9140_4cb5_47ed_91cd_78362f751be9
stoichiometry: 1.0
species: 801761
type: SpeciesReference

816435
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#c1f08ff8_4206_44d4_b97f_8980aa8e732a
stoichiometry: 1.0
species: 803111
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0a805426_7b81_4977_9982_e2bcd57da779
stoichiometry: 1.0
species: 802362
type: SpeciesReference

813565
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#e71b5628_07da_4fa9_9b8e_cf466574a885
value: 0.4
type: LocalParameter

818965
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#cfe59013_0419_4e27_83fb_39ce60e095e0
stoichiometry: 1.0
species: 802301
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ace0c328_ea69_4498_b63e_72eef76a4be6
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#f6cf914b_b146_45e1_ac0f_b0ddb5243d42
stoichiometry: 1.0
species: 801761
type: SpeciesReference

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stoichiometry: 1.0
species: 802721
type: SpeciesReference

814199
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#a22c50b2_4dfb_44e3_aa13_7f85b7b1b37d
stoichiometry: 1.0
species: 803411
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_917db875_10cf_440a_9e19_965fbff4ab2c
stoichiometry: 1.0
species: 803561
type: SpeciesReference

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stoichiometry: 1.0
species: 801731
type: SpeciesReference

802961
has part: P09560
name: Scaffold_MAPK-P_RAF-P
in compartment: 801486
boundary condition: false
has part: P26696
type: Species
initial amount: 0.0
has only substance units: true
constant: false
initial concentration: NaN

http://identifiers.org/biomodels.db/BIOMD0000000014#_23e4755a_d00d_47ac_9159_c7a3b089a34c
stoichiometry: 1.0
species: 802271
type: SpeciesReference

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stoichiometry: 1.0
species: 801641
type: SpeciesReference

823794
is version of: REACT 996
reversible: false
fast: false
name: binding of RAF and RAFK
is version of: GO:0031435
type: Reaction

804677
fast: false
reversible: false
is version of: http://identifiers.org/ec-code/2.7.11.25
is version of: GO:0006468
name: phosphorylation of MEK
is version of: GO:0004709
type: Reaction

813355
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#a61d0ba3_39d9_4b70_a713_47553aeaabe4
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_3abaefd8_6f09_4fcc_95a0_0004359170a9
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#cefc8d21_41b9_459e_8caf_90b11049402a
stoichiometry: 1.0
species: 803771
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_492397ef_1286_4248_948d_c7f9a40a3810
value: 0.0
type: LocalParameter

816295
fast: false
reversible: false
name: binding of RAF on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_98f33489_086b_4ab8_b754_0576d15c6655
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7c8dd651_8a2e_42f3_a87d_6ca6a20fd1da
stoichiometry: 1.0
species: 802121
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b96d5c21_8664_4e06_a576_772b890b5bc7
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#f63ae2c4_3f22_481a_a140_b8ba6dcc5b09
value: 0.8
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_10a35343_b518_4c7f_9ba9_d95b3362088e
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_21ad5993_5784_45ff_9e77_b573fab659f9
stoichiometry: 1.0
species: 802541
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6e45d4bc_24ef_4771_9bda_fc6ff40afd2d
stoichiometry: 1.0
species: 803261
type: SpeciesReference

804885
is version of: GO:0006470
reversible: false
name: dephosphorylation of MEK-P
type: Reaction
fast: false
is version of: http://identifiers.org/ec-code/3.1.3.16

http://identifiers.org/biomodels.db/BIOMD0000000014#_1ec63fb1_a3b2_4d5a_8f8a_954b8b3f4a3a
stoichiometry: 1.0
species: 802181
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a8ad46bc_006a_4e68_83fc_9aecdf346b16
stoichiometry: 1.0
species: 801641
type: SpeciesReference

811395
fast: false
reversible: false
name: binding of MEK on scaffold
type: Reaction

819804
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_20405a7c_5d8d_4e65_b2f7_c0050da49d97
stoichiometry: 1.0
species: 803441
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c86fa500_170e_4d9f_89df_a452a0fb2831
stoichiometry: 1.0
species: 802991
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7c6aedb9_86eb_4202_8a5f_c9ddd37b2413
stoichiometry: 1.0
species: 803441
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5ad9d891_41c3_4a67_b1f4_0ba0449b7442
stoichiometry: 1.0
species: 803921
type: SpeciesReference

810975
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#c2049281_d2bb_4b5c_a29c_d82638b79ec3
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0d44602e_bac5_412f_845d_ef01dc171b3a
stoichiometry: 1.0
species: 801641
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3ec00879_e07c_4709_ac0f_d0710a4e98ca
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_34893fe8_1632_4873_bd41_d2e661322e2a
stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_356471a5_8c81_498e_8d84_eed18ff78a70
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_953a4c1d_82e5_47a9_8332_19ba2d89e3f1
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_7b71834f_00aa_4d58_aeb9_0a93509fcfe9
stoichiometry: 1.0
species: 802181
type: SpeciesReference

803741
has only substance units: true
initial amount: 0.0
type: Species
name: Scaffold_MAPK_RAF
constant: false
boundary condition: false
initial concentration: NaN
has part: P26696
has part: P09560
in compartment: 801486

http://identifiers.org/biomodels.db/BIOMD0000000014#_9417f559_46c3_40f7_8fc7_d0bf8dcae925
stoichiometry: 1.0
species: 803291
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_14493653_300a_477a_b014_482daac67e1b
stoichiometry: 1.0
species: 802541
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5763f635_17fe_4e83_836a_3cbe2e27415b
stoichiometry: 1.0
species: 802721
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#c0ae9308_1be7_4574_81ae_1f18ffb81529
stoichiometry: 1.0
species: 802271
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_57781d12_f985_4322_a1df_970f27beefbd
stoichiometry: 1.0
species: 803831
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_97bff562_8eaf_44b5_8e5d_440410550084
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3e0d985f_1f4f_4b97_b36b_ef9a24e9e4c4
stoichiometry: 1.0
species: 803651
type: SpeciesReference

820987
fast: false
is: GO:0000187
reversible: false
name: phosphorylation of MAPK-P on scaffold
is: GO:0004708
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.37

http://identifiers.org/biomodels.db/BIOMD0000000014#_16852a75_911b_4a8d_b424_996be48550a2
stoichiometry: 1.0
species: 803141
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_4a2bc093_a36a_4b75_9f20_7531890f7ec3
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_6c53983f_6885_4755_8a93_8448bd8f48b6
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#f6c2a0a7_1a2e_441e_9b05_ade461bc7195
stoichiometry: 1.0
species: 802211
type: SpeciesReference

823864
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF_RAFK
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#fd50501e_815a_4627_87e2_849b94be6fc0
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_0450a33b_d75e_4093_9bda_5229fd68ae51
stoichiometry: 1.0
species: 803261
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_39c968e3_db67_42c9_bca0_e23526797103
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_20aff140_ddba_47a0_92a0_bb7095f518cd
stoichiometry: 1.0
species: 801761
type: SpeciesReference

820084
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

807475
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_926d44b5_d2a9_45f8_b257_1a7270b0e3be
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6d781497_3fa3_4033_ac8f_0aff4d0c19bc
stoichiometry: 1.0
species: 801761
type: SpeciesReference

804955
reversible: false
type: Reaction
is version of: GO:0031435
is version of: GO:0031434
is homolog to: REACT 143
name: binding of MEK-P and RAF-P
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_7cc9c105_8060_4192_9e07_7eaf10e7e624
stoichiometry: 1.0
species: 802751
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bfa47bae_c508_4a1a_99af_dab7484cfd2d
stoichiometry: 1.0
species: 803322
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#a63035f7_72f4_4ab3_bf9d_d20f33a08931
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#b99b1c9a_be4d_479c_bf9d_53faf1f4b9be
value: 0.0
type: LocalParameter

808245
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

802362
has part: Q05116
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: Scaffold_MEK-P
type: Species

812725
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_320f1d40_d4e4_4d17_9139_fbd86c13f396
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#b131d30d_4425_4d36_8bc0_42d52a194c09
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_589d1cce_b308_499e_afa2_7c3bf71a03f9
stoichiometry: 1.0
species: 802511
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_83a98ff1_334b_4815_94c5_cf947f2dbe60
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_84a2402a_b5fb_4da0_8070_3d06f188eb4f
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_68d9c2a6_df30_47ca_af15_f2820bc4e1e0
stoichiometry: 1.0
species: 802631
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#e8fb1fc2_f086_4d8c_af28_3138f80d4464
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_68dcf62c_af49_4316_8605_ecb418e92250
stoichiometry: 1.0
species: 803082
type: SpeciesReference

802001
name: MAPK-P_MAPKPase
initial concentration: NaN
has only substance units: true
boundary condition: false
constant: false
in compartment: 801486
has part: Q90W58
initial amount: 0.0
has part: P26696
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#a569cc4d_2782_4644_a240_92b3f0d3c253
stoichiometry: 1.0
species: 802481
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_79d01386_96fe_4460_9c75_7eec093bfb87
stoichiometry: 1.0
species: 802151
type: SpeciesReference

802691
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
has part: P09560
has only substance units: true
name: Scaffold_MAPK_MEK_RAF-P
has part: Q05116
boundary condition: false
has part: P26696
constant: false
type: Species

801582
is version of: IPR003577
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.1
in compartment: 801486
name: RAF kinase
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#_1d6d00c5_3d05_47f3_97d3_9f5147831111
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_95c149e2_0f74_4e46_907e_c1a200fead60
stoichiometry: 1.0
species: 801582
type: SpeciesReference

803351
name: Scaffold_MAPK-PP_MEK
has part: Q05116
boundary condition: false
has part: P26696
in compartment: 801486
initial concentration: NaN
constant: false
initial amount: 0.0
type: Species
has only substance units: true

http://identifiers.org/biomodels.db/BIOMD0000000014#ec825d48_6d26_465c_be7c_e2e550b5dabf
value: 0.0
type: LocalParameter

806635
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_8683fd4a_f563_4116_b04a_d14ba725b54d
stoichiometry: 1.0
species: 802332
type: SpeciesReference

810908
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#d5680dde_1228_44ed_b809_9140bdc65e62
stoichiometry: 1.0
species: 803322
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_73eaff4d_adc0_4c2b_8f1c_06a8dd20e4eb
stoichiometry: 1.0
species: 804011
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0aac00dc_d471_442c_9437_eaa102fd31a2
stoichiometry: 1.0
species: 802392
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_162ce5a1_f015_4241_9ffd_76abcbf83362
value: 0.0
type: LocalParameter

818685
fast: false
reversible: false
name: binding of RAF-P on scaffold
type: Reaction

812305
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

814825
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_169e3df1_706d_4b40_8f1e_3dae7fb095ba
stoichiometry: 1.0
species: 802541
type: SpeciesReference

810415
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_7ffe0563_5691_474d_a082_5a0c68d64200
stoichiometry: 1.0
species: 802691
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0d0b525f_7219_4bb2_b3ed_adf7ed2a949c
value: 0.1
type: LocalParameter

801761
is version of: Q05116
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.0
in compartment: 801486
name: MEK-P
type: Species

http://identifiers.org/biomodels.db/BIOMD0000000014#f1dda9c7_44b9_47da_aa98_f0abd9f338f3
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_8e4cef4e_a241_4c78_8061_4af06989963e
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_278400c3_11a9_498e_862e_82b66934bca5
stoichiometry: 1.0
species: 802332
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d6c44c31_3cf8_44df_b86c_b3b9ae528401
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3ba3c2a7_d930_403d_8e2d_3f19a9c6b33c
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#a4fcea54_05c0_414d_994c_bc15f1fcd24c
stoichiometry: 1.0
species: 802901
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_224485ae_dbae_43f9_8af1_e36ba34d6831
stoichiometry: 1.0
species: 803082
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_85c3bed8_f300_4825_9a2c_d0fc7ffd491d
stoichiometry: 1.0
species: 802481
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_05025b9c_447f_4737_bb36_333e6d850c1a
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_23f6f086_202c_4dac_b383_d523449ea865
stoichiometry: 1.0
species: 802511
type: SpeciesReference

806145
is version of: GO:0000188
is version of: http://identifiers.org/ec-code/3.1.3.16
fast: false
type: Reaction
name: dephosphorylation of MAPK-PP
reversible: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_69389020_1b15_45d0_9d6a_2704573e5dcb
stoichiometry: 1.0
species: 802451
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#e3076b87_20ef_4902_8ca7_1c280946c84a
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7c1bc48a_6050_43e6_b728_e0b0d6410c30
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_83739d7d_2f94_48cd_8140_69d4c375a1fa
stoichiometry: 1.0
species: 802751
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5c736fc6_71ea_47de_b72e_0e3888b62ba6
stoichiometry: 1.0
species: 803471
type: SpeciesReference

802511
initial concentration: NaN
constant: false
boundary condition: false
has only substance units: true
initial amount: 0.0
in compartment: 801486
has part: P09560
name: Scaffold_MEK-PP_RAF-P
has part: Q05116
type: Species

818056
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

816645
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

801821
is version of: P09560
constant: false
boundary condition: false
has only substance units: true
initial concentration: NaN
initial amount: 0.3
in compartment: 801486
name: RAF
type: Species

823374
fast: false
is version of: GO:0031435
reversible: false
is version of: REACT 996
name: binding of RAF and RAFK
type: Reaction

815385
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MEK from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#f5a13564_7066_4b46_854d_e385349ba94f
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_0d6f48ec_4430_43b0_9185_179e2262a84f
stoichiometry: 1.0
species: 802871
type: SpeciesReference

823934
is version of: GO:0008349
reversible: false
is version of: http://identifiers.org/ec-code/2.7.11.1
fast: false
type: Reaction
is version of: GO:0000185
name: phosphorylation of RAF on scaffold

http://identifiers.org/biomodels.db/BIOMD0000000014#_9499c04f_f46c_4e5b_978a_bda23f2a718f
stoichiometry: 1.0
species: 802362
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_75b98a9d_7144_48bc_8fc0_1c93d3abfabc
stoichiometry: 1.0
species: 802961
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b669806f_f2f4_4ddc_b758_822b2fff232f
value: 0.05
type: LocalParameter

813075
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

811675
fast: false
reversible: false
name: binding of MEK-P on scaffold
type: Reaction

807825
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

822954
is version of: REACT 996
name: binding of RAF and RAFK
reversible: false
is version of: GO:0031435
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_053e8867_aff2_45b3_a12a_f9395726cb14
stoichiometry: 1.0
species: 801971
type: SpeciesReference

816924
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF from scaffold
type: Reaction

803021
has part: P26696
in compartment: 801486
constant: false
name: Scaffold_MAPK-P_MEK_RAF
has part: P09560
has part: Q05116
initial concentration: NaN
initial amount: 0.0
type: Species
has only substance units: true
boundary condition: false

http://identifiers.org/biomodels.db/BIOMD0000000014#f398c2df_083f_477e_9455_913de16d61da
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ebfe7c59_09ff_48ec_aa18_c78d51df339a
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d8b31d27_20bd_445b_8210_705d8c77c3a9
stoichiometry: 1.0
species: 803111
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7191a928_f1e5_417f_a69b_946c8cd0042c
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_427dccbd_c72e_4388_a5c2_e53833c0a20b
stoichiometry: 1.0
species: 801641
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_6985cf4c_2e18_4fde_a95d_2efd7ab464c4
stoichiometry: 1.0
species: 803231
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_5aba0010_8faa_4cc1_b660_f7853eee17e6
stoichiometry: 1.0
species: 803382
type: SpeciesReference

808315
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK-P on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#afd9224d_811e_4d3a_8062_094df4294904
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#cae48680_319c_4cf7_ad3f_5626eb4d6ad1
stoichiometry: 1.0
species: 802781
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ae0be53e_e03e_4b9f_883c_f7bbd8e147aa
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#bd781f28_1591_4204_8c01_1e81b88e40d1
stoichiometry: 1.0
species: 801761
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f194c216_cedc_4396_a673_e84e10faa776
stoichiometry: 1.0
species: 802271
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d92abcf1_f9cf_4a3a_8d4f_d1920a6acba6
value: 0.1
type: LocalParameter

824004
reversible: false
type: Reaction
name: binding of RAF and RAFK
is version of: REACT 996
fast: false
is version of: GO:0031435

http://identifiers.org/biomodels.db/BIOMD0000000014#_4c867a3c_e1fa_48f1_ba14_aba9510cf0ca
value: 0.05
type: LocalParameter

814615
fast: false
reversible: false
name: binding of MEK-PP on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#d70faf00_f07d_4303_bceb_7002af068cad
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_35f16be1_c9d1_4054_9189_ffe0cc0d33c0
stoichiometry: 1.0
species: 803531
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bc23dbd8_3d6a_4649_9b85_faba3ac688c3
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_01235356_3a08_4c8b_9776_a2efefd1d0bf
stoichiometry: 1.0
species: 802332
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#faa0a5db_6eff_43c4_af9c_84d1c3544179
stoichiometry: 1.0
species: 801701
type: SpeciesReference

805305
is version of: GO:0006470
is version of: http://identifiers.org/ec-code/3.1.3.16
name: dephosphorylation of MEK-PP
reversible: false
type: Reaction
fast: false

http://identifiers.org/biomodels.db/BIOMD0000000014#_21197a34_2886_40c1_84de_0c82aa69203d
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#b9b3f34b_b936_4bce_b4ef_18977875f818
stoichiometry: 1.0
species: 801761
type: SpeciesReference

810205
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-PP from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_65313d43_86f5_4229_b5d5_f1d83a5e085a
stoichiometry: 1.0
species: 803082
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_7793b9c4_d8d7_44f5_b337_e71d2cee0d96
stoichiometry: 1.0
species: 801851
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f621e872_7820_464e_9879_6f024d8fb13b
stoichiometry: 1.0
species: 802241
type: SpeciesReference

808945
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#c66133fb_e082_4f44_a178_8168f3fab8e2
stoichiometry: 1.0
species: 801791
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#ccb56eac_cc29_44a7_b600_f8c18ad4acfe
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_3de6c807_2176_45d1_980e_85a53dc3670d
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_1a42dbf0_1cbd_4829_a429_c5f91e894151
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#cdf50dab_10dd_439d_8fb6_5115b34c9224
stoichiometry: 1.0
species: 802541
type: SpeciesReference

820714
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of RAF-P from scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_3228da01_63bd_4aeb_b858_b2341bac6c3a
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_1130d5e6_6cbd_4aa3_8576_53c3150098a6
stoichiometry: 1.0
species: 803621
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_836a3b64_60fe_4d24_bf45_e5a1d9105c93
stoichiometry: 1.0
species: 801582
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_91249bd8_699d_480b_bbf1_0949e86e5d78
stoichiometry: 1.0
species: 801821
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_9e9bea29_0f87_478f_b24e_5bd4e8298f68
stoichiometry: 1.0
species: 802301
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_2bf69d64_e119_44e5_8ecc_8900dc54d661
stoichiometry: 1.0
species: 801701
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#fc2f3e1f_178b_4906_9153_215906e9f7e8
stoichiometry: 1.0
species: 802931
type: SpeciesReference

806425
is version of: GO:0043241
fast: false
reversible: false
name: dissociation of MAPK from scaffold
type: Reaction

807195
is version of: GO:0051019
fast: false
reversible: false
name: binding of MAPK on scaffold
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#dd323536_9f22_460f_8c67_e1a5d200f9e2
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_83440eed_901a_405c_8490_3551e6aaf5b9
stoichiometry: 1.0
species: 802092
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_3ba4d06a_69b0_4f8b_a318_d1490c3f85c6
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_3dca561e_fabd_4b8f_a87f_2695730c7dad
value: 0.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#ddfe3613_1bbb_4755_a6f7_ee5a8cdc466d
stoichiometry: 1.0
species: 801671
type: SpeciesReference

822744
is version of: REACT 996
fast: false
is version of: GO:0031435
type: Reaction
reversible: false
name: binding of RAF and RAFK

http://identifiers.org/biomodels.db/BIOMD0000000014#_447aef08_edd5_4b8b_9abd_8b2466791975
stoichiometry: 1.0
species: 801731
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#bf6ece91_77a8_4f29_a5d9_e2bfa0832be7
stoichiometry: 1.0
species: 802691
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#f1613fe7_e09a_40f9_8506_e929f72c9a10
stoichiometry: 1.0
species: 803051
type: SpeciesReference

805725
is version of: http://identifiers.org/ec-code/3.1.3.16
fast: false
reversible: false
name: dephosphorylation of MAPK-P
type: Reaction

http://identifiers.org/biomodels.db/BIOMD0000000014#_8d5d0f55_b615_4f1f_b457_0aaad84af4fc
stoichiometry: 1.0
species: 802332
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#_36ed5356_8205_4efe_b1ba_385eaecd9613
value: 10.0
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#_7977a005_3b6b_4a2b_81cf_0a77081fa9e3
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/BIOMD0000000014#c07f8f7a_957a_4b5e_aa61_824c15021de5
stoichiometry: 1.0
species: 802661
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#d11f90cd_0091_4b6c_bc6d_eee399406078
stoichiometry: 1.0
species: 802721
type: SpeciesReference

http://identifiers.org/biomodels.db/BIOMD0000000014#b199b6b7_92ce_473f_88f3_4bacb5aba42d
stoichiometry: 1.0
species: 801851
type: SpeciesReference

W3 CDTF: Mon Jun 03 14:36:47 BST 2013

given: Bruce
family: Shapiro

orgname: NASA Jet Propulsion Laboratory