http://identifiers.org/biomodels.db/MODEL1303260007#e95beb61_5642_4c00_8675_9350f1cbe990
value: 0.0098
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#cd9f9c02_c981_42e0_a417_0304f82804e8
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_6f477200_55ce_48db_a6e6_9a7d8e51f9a9
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#ab33e305_416c_4e3e_9bf6_f64907713445
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta ENO
type: Reaction
is: SBO:0000176
fast: false
is: R00658
name: enolase
modifier: MODEL1303260007#
is version of: http://identifiers.org/ec-code/4.2.1.11
is version of: GO:0004634
reversible: true

meta PDC1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.266952694557084
initial amount: NaN
in compartment: meta cell
name: PDC1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_780ec73b_f87a_46ad_afd5_74ae12ad4b4b
value: 0.031
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#ac3d0e21_1e0d_403e_ba50_53a9128d587b
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#_7971b594_1dd4_41ca_bf77_4610151e5643
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_5d4d1e83_ccc5_4438_9a9c_ab59e394ecd4
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

meta HXK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0041951864287446
initial amount: NaN
in compartment: meta cell
name: HXK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#e3a5a412_c3ba_4a9b_96da_511beefa31c4
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_359d319f_9a26_4c34_9532_e2f97cf15972
value: 0.195
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#a7d53107_1f3d_49f5_bc99_63fc2123032b
value: 30.0
type: LocalParameter

meta UDP
boundary condition: false
has only substance units: false
is: SBO:0000247
name: UDP
in compartment: meta cell
is: CHEBI:17659
initial amount: NaN
type: Species
initial concentration: 0.2815
constant: false

http://identifiers.org/biomodels.db/MODEL1303260007#fe3e6802_19a1_4b71_9171_16887b883630
value: 0.069
type: LocalParameter

meta EtOH
boundary condition: true
has only substance units: false
type: Species
is: SBO:0000247
name: ethanol
initial concentration: 55.472577854384
in compartment: meta cell
is: C00469
is: CHEBI:16236
constant: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260007#_1fa1f7ac_27d7_4918_8bbd_ec0787f3d1f9
constant: false
value: NaN
name: glycerate phosphates
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260007#_18b930f7_825e_44c6_99b9_a805e2242dec
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta cell
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260007#_8ec6551b_6155_4aea_a249_8b403138190f
value: 259.220125786164
type: LocalParameter

meta PGM2
is: P37012
initial amount: NaN
initial concentration: 3.1467219294138E-4
is encoded by: S000004711
constant: true
name: PGM2
boundary condition: true
has only substance units: false
in compartment: meta cell
is: SBO:0000252
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#f229eaa0_aa42_4c4f_b808_eaf214d8255b
value: 43.0833333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_74bd0d47_9848_4025_85c9_ae21744c9490
value: 7500.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_8d9e404c_71dd_4291_9014_67dca0db2bae
value: 1.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_6d97b1ba_32bf_4b23_9214_e69a6ce616ca
stoichiometry: 1.0
species: meta ACE
type: SpeciesReference

meta FBA1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0367018202831552
initial amount: NaN
in compartment: meta cell
name: FBA1
type: Species

meta GPD
type: Reaction
is: http://identifiers.org/ec-code/1.1.1.94
name: glycerol 3-phosphate dehydrogenase
is: SBO:0000176
is: R00842
fast: false
modifier: MODEL1303260007#
reversible: true

http://identifiers.org/biomodels.db/MODEL1303260007#_4f748e75_a0d2_4309_a861_c3f2b3e5d6db
value: 0.02285
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_45954ecd_6fee_4fcb_a91c_ea768418acd5
value: 3.0
type: LocalParameter

meta ENO2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.493611573294543
initial amount: NaN
in compartment: meta cell
name: ENO2
type: Species

meta GLCx
in compartment: meta extracellular
boundary condition: true
constant: true
is: CHEBI:4167
type: Species
is: C00031
initial concentration: 74.0
is: SBO:0000247
initial amount: NaN
name: glucose
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260007#afcd3398_4838_4ddd_a48b_2befff95fab0
value: 0.14
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#e420d49b_30d1_47c5_a34d_adee7733d65a
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_13223ecc_c1f6_418f_bcf2_92aab840798a
stoichiometry: 0.75
species: meta SUC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_7094c6fe_d735_4f42_8a20_32cb655295ac
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_0059b9de_32cb_40a3_997a_5aed75352001
value: 0.23
type: LocalParameter

meta RHR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0127951193429578
initial amount: NaN
in compartment: meta cell
name: RHR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_8c73dbaa_6cd0_46a1_a4ff_76896d41bb59
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_56df735c_6cdb_40da_a34e_1b3005b4609d
stoichiometry: 1.0
species: meta F16bP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_656794b2_de5a_46e7_beff_529b7de21234
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_29162b29_8530_44ef_8a60_058667d7cf6d
stoichiometry: 1.0
species: meta GLY
type: SpeciesReference

meta HXK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0153328384926289
initial amount: NaN
in compartment: meta cell
name: HXK2
type: Species

meta TPS
fast: false
name: T6P synthase
is: SBO:0000176
reversible: false
is version of: http://identifiers.org/ec-code/2.4.1.15
type: Reaction
modifier: MODEL1303260007#

http://identifiers.org/biomodels.db/MODEL1303260007#_0c2f531f_2319_44d5_b2c3_987093c9e7d3
value: 0.75
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_06da2369_87dd_4421_8ad6_86a1fb01679f
constant: true
value: 1.39784619487425
type: Parameter

meta PDC6
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0016352160527653
initial amount: NaN
in compartment: meta cell
name: PDC6
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#d82b8a5b_1d37_4624_94b2_97857dc04449
value: 0.06
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_1eeb0b8b_da53_4a61_a0b5_0787c9a66415
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_0bc22357_9f51_44e8_821e_bf07ceb27b2f
name: mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260007#d02ff5aa_f53d_4b3a_9813_6dff39c08981
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#b3d52e26_b740_4338_ad9c_766ebee07fee
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_75d7179b_cab6_4e75_ab5b_351fc532947d
units: dimensionless
value: 3200.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_07841962_c513_4453_9364_f3c0c2c0759e
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

meta ENO1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.171592988538958
initial amount: NaN
in compartment: meta cell
name: ENO1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_01f6482a_a3b9_46db_9f0a_85f0e5713211
stoichiometry: 1.0
species: meta AMP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_3ca9f7ae_62bb_48d8_99cc_7983f694d704
value: 2.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_6b036d2d_79fc_42bd_8ecd_cb934432dcb1
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_1594e264_3b6c_450b_a1ad_bcf2c0fe38c8
value: 14.2966666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_13d70d1c_3665_456b_97dd_942da8a91fc2
constant: true
value: 6.022140000000001E20
name: Avogadro constant
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260007#_7161c970_d751_4110_87e3_f3ed589cc721
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#_048be488_a504_4d79_a33d_fd5912f99a62
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta G3P
has only substance units: false
name: glycerol 3-phosphate
constant: false
initial amount: NaN
boundary condition: false
is: CHEBI:15978
type: Species
is: SBO:0000247
in compartment: meta cell
initial concentration: 0.068500732297821
is: C00093

meta SUC
is: SBO:0000247
constant: true
initial concentration: 0.0
initial amount: NaN
is: CHEBI:30031
boundary condition: true
name: succinate
type: Species
is: C00042
has only substance units: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260007#b7769bb9_3b96_4f0d_af0d_51aa0abc90a1
units: dimensionless
value: 6.7
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#dc0bc25b_4bfd_4e12_8212_1e6fcda965c5
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_65f576bd_f600_46a3_990a_2701ad35b6e2
value: 3.36
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_9440d978_7cae_4c4a_b502_e3d315c4afdc
value: 0.0721
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_770736e7_1ec0_46f0_bf11_954663f92654
units: dimensionless
value: 0.0174
type: LocalParameter

meta PDC
name: pyruvate decarboxylase
modifier: MODEL1303260007#
is: SBO:0000176
reversible: false
is version of: http://identifiers.org/ec-code/4.1.1.1
type: Reaction
is: R00636
is version of: GO:0004737
fast: false

http://identifiers.org/biomodels.db/MODEL1303260007#_1f9eaf22_3e61_44ab_99c3_08118af2df85
value: 0.5
type: LocalParameter

meta TPP
reversible: false
is version of: http://identifiers.org/ec-code/3.1.3.12
name: T6P phosphatase
type: Reaction
fast: false
modifier: MODEL1303260007#
is: SBO:0000176

meta PDC5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00308868608169189
initial amount: NaN
in compartment: meta cell
name: PDC5
type: Species

meta F16bP
in compartment: meta cell
initial amount: NaN
is: SBO:0000247
constant: false
type: Species
initial concentration: 1.14580464751733
is: CHEBI:28013
has only substance units: false
name: fructose 1,6-bisphosphate
boundary condition: false
is: C05378

http://identifiers.org/biomodels.db/MODEL1303260007#d03b646d_4578_4392_8934_e85a2c06c12f
value: 3.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_1e44253b_3613_4df3_b85b_aa1cf25421d6
units: dimensionless
value: 0.397
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#fcc250be_bfb1_49f2_b484_6fafa3598361
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_090a8582_579c_4370_b4b5_03ec419f3c4c
value: 0.53
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_7a705ea4_aae9_4c85_84e4_6875e79b0118
stoichiometry: 3.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_14fc3566_4f8b_4e4b_b144_b228fb3b8dd5
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#a8667a30_37d3_4e48_a249_bbe6775f4bf0
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#dab957a9_df17_4610_bf32_e4c2b11da47c
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_431261b0_33aa_42ad_a6f3_b0dbf1bb141d
value: 10.2
type: LocalParameter

meta GLK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0112717406104807
initial amount: NaN
in compartment: meta cell
name: GLK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_30be9c07_2c4b_4b64_b96e_d0151bbb0ee9
units: dimensionless
value: 6500.0
type: LocalParameter

meta HOR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0013683673909939
initial amount: NaN
in compartment: meta cell
name: HOR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_80538d1e_340d_4584_95ee_eb6bcae5be36
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_530c834a_55fd_4bd5_b318_b42d209b69b0
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_7f469ae3_4b99_435d_8389_037b86285f15
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#b0c97458_5c11_4503_9acd_5b2c479f4698
stoichiometry: 1.0
species: meta TRH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_57b287ad_3583_4af4_9d59_3fffe0376041
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#c0787222_0c83_4b0a_953a_21df3eaac125
stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

meta TPI
is: R01015
type: Reaction
fast: false
modifier: MODEL1303260007#
reversible: true
is: SBO:0000176
is version of: GO:0004807
is version of: http://identifiers.org/ec-code/5.3.1.1
name: triosephosphate isomerase

meta PYK
fast: false
modifier: MODEL1303260007#
name: pyruvate kinase
is version of: GO:0004743
reversible: true
is: SBO:0000176
type: Reaction
is: R00200
is version of: http://identifiers.org/ec-code/2.7.1.40

http://identifiers.org/biomodels.db/MODEL1303260007#_44da00b0_9b1d_4c66_96a1_adfdf9cfadd0
name: per second
type: SBMLUnitsDef

meta PGM
fast: false
name: phosphoglucomutase
is version of: http://identifiers.org/ec-code/5.4.2.2
type: Reaction
reversible: true
is: SBO:0000176
modifier: MODEL1303260007#

http://identifiers.org/biomodels.db/MODEL1303260007#_7fde49aa_dcf8_46b6_9716_9dbe8264404f
value: 0.00549663630823988
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#dd6ab782_4911_4757_964a_8237b83759d7
constant: true
units: dimensionless
value: 2000.0
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260007#_2062b246_73cc_4a57_896e_e36097906e76
units: dimensionless
value: 800.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_1652ea13_6dbf_47d6_b3c3_51b288224506
stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_2ee45458_bd62_403c_a1c0_48c162e9d45d
value: 19.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_67fe8aad_916f_4727_85df_2460349964dc
units: dimensionless
value: 0.29
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#c8caceae_7bf4_4764_b0e8_8e054fa5bad5
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_9534a279_6b42_43f4_b5be_9b96ff7bc7af
value: 0.865
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_4d74aecb_0c49_4048_a60d_da129410ee55
value: 0.15
type: LocalParameter

meta T6P
is: CHEBI:18283
has only substance units: false
type: Species
is: SBO:0000247
initial amount: NaN
boundary condition: false
name: trehalose 6-phosphate
initial concentration: 0.02
constant: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260007#_6834d159_4ca2_4d17_9356_df86cbb8901a
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#ecac0dd5_62ad_4cf4_b34f_95bef0ee9eef
value: 0.293
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_3a8ece9e_3d39_45ec_9b8e_c5ca36c0b4c0
value: 0.00345026988011002
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#fedd8d9c_cd32_4c42_98b4_f36af08c4bd2
value: 209.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#f6da00aa_598e_4506_ba21_fc48536ea552
stoichiometry: 2.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_7ad6f9e4_124d_455a_843b_9c3b49b69350
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta PGK
is version of: GO:0004618
name: 3-phosphoglycerate kinase
modifier: MODEL1303260007#
fast: false
type: Reaction
is: R01512
reversible: true
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.7.2.3

http://identifiers.org/biomodels.db/MODEL1303260007#d09be39b_584f_4a9c_8f06_a0fe8b4cc5b3
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_06004d16_bb1d_46b7_9a47_96234d6db876
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#acdebccb_26f6_4c5d_b8f7_371671845aed
value: 63.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_8aeed64d_c2a6_4add_8aa0_ef49f8db1239
value: 0.21
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_5611a332_d5c9_41d3_8417_e41e539782e5
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#fc5c3d5c_5c05_4fec_a6ac_90fd606d1212
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_9b77f3b6_04e4_41ed_b22e_432975f5e3aa
value: 1.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_73b33202_de9d_47eb_9773_b4152dff93a1
units: dimensionless
value: 1.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#e895c444_ddbd_4696_8323_6cd97855222a
units: dimensionless
value: 3.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_80e01c05_64a7_4d77_b905_42e4f9588c38
value: 0.613666666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#c64f403e_1254_401a_b1b6_16dfb1f1b520
value: 0.3
type: LocalParameter

meta ATPase
reversible: false
is version of: GO:0016887
name: ATPase
modifier: MODEL1303260007#
type: Reaction
is: SBO:0000176
fast: false

http://identifiers.org/biomodels.db/MODEL1303260007#_55514c76_7bac_4880_b7da_c31311bfa9d1
value: 0.93
type: LocalParameter

meta FBA
is version of: GO:0004332
name: fructosebisphosphate aldolase
modifier: MODEL1303260007#
is: R01068
is: SBO:0000176
fast: false
reversible: true
type: Reaction
is version of: http://identifiers.org/ec-code/4.1.2.13

meta PGI
modifier: MODEL1303260007#
is version of: http://identifiers.org/ec-code/5.3.1.9
is version of: GO:0004347
name: phosphoglucose isomerase
type: Reaction
fast: false
reversible: true
is: SBO:0000176
is: R00771

http://identifiers.org/biomodels.db/MODEL1303260007#_118d6151_4f7b_4a6f_9661_1980993de7dc
value: 0.0995
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#ad9b448e_8623_41fa_9ad2_65b4a5c95a8a
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#dcc23350_791e_4873_b0d3_45fb0e670354
value: 21.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_4b95fd26_afd3_46ed_b773_2e8ee6fe4f0e
value: 0.0035
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#c4fe9d6b_1c02_41af_91fe_0cfb854e82d1
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#ee069b62_12d9_46db_ad4f_486f56f7ef10
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_0bb7fedf_93b6_4002_9c82_a872919a5892
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#_0597e2bb_a3ce_451b_9fed_50be250f5995
value: 0.783333333333333
type: LocalParameter

meta PGM1
is encoded by: S000001610
is: SBO:0000252
is: P33401
constant: true
initial concentration: 8.15573865768647E-4
name: PGM1
boundary condition: true
in compartment: meta cell
type: Species
initial amount: NaN
has only substance units: false

meta PFK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00975915538330228
initial amount: NaN
in compartment: meta cell
name: PFK2
type: Species

meta PYR
boundary condition: false
has only substance units: false
in compartment: meta cell
is: CHEBI:15361
is: SBO:0000247
type: Species
initial amount: NaN
constant: false
name: pyruvate
is: C00022
initial concentration: 0.527117851793548

http://identifiers.org/biomodels.db/MODEL1303260007#a73470db_29da_4ce8_85d5_45d3125145b4
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#_2ef8b8e9_1554_4f2c_bdf4_ff9612e53665
name: UDP to UTP pseudoreaction
fast: false
modifier: MODEL1303260007#
type: Reaction
reversible: false
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260007#_0ba37bce_8e0e_4b56_b221_2268def8ce55
value: 3.35
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#cb7efc2b_341c_4325_8448_ec44031083c7
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#cd30e1e2_ce3e_4979_a2ec_238797ad1c19
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_961bbf38_cfe9_4ea6_b5a8_beb5c41d6590
value: 1.0
type: LocalParameter

meta F6P
is: CHEBI:16084
initial amount: NaN
type: Species
constant: false
is: SBO:0000247
in compartment: meta cell
initial concentration: 0.0588603054728053
boundary condition: false
has only substance units: false
is: C05345
name: fructose 6-phosphate

http://identifiers.org/biomodels.db/MODEL1303260007#_934c7b6b_71d2_4d08_a37e_4225e57e11df
constant: true
value: 1.59
type: Parameter

meta PFK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0116962574765781
initial amount: NaN
in compartment: meta cell
name: PFK1
type: Species

meta PFK
is version of: GO:0003872
type: Reaction
is: R00756
name: phosphofructokinase
fast: false
modifier: MODEL1303260007#
is version of: http://identifiers.org/ec-code/2.7.1.11
reversible: false
is: SBO:0000176

meta P3G
constant: false
boundary condition: false
is: CHEBI:17794
has only substance units: false
initial amount: NaN
is: SBO:0000247
initial concentration: 0.117456252783611
type: Species
is: C00197
name: 3-phosphoglycerate
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260007#_59942d8f_4157_40e2_9561_336627e69361
units: dimensionless
value: 0.045
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_7d37f3e7_409f_48f0_9a45_ba990c755ff2
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_69cfe912_afb5_499b_88ff_2c07d6ee9090
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_59ec809e_61ec_4411_8df5_61d8a2bc5d66
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#abcdf63c_b47d_45df_85fa_fbcae9a93bc2
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#a7427c4a_9a3e_48f2_a9cc_a1117faf40e3
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#a878e782_b740_4e85_9aaf_ac6de0d17255
value: 0.003
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#b70685a3_8251_4f01_8155_fe7f25026c64
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#b5940779_1444_449f_ba73_d190c5ccb64b
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_2ac7b252_2228_4e69_8af2_e13ec542358f
units: dimensionless
value: 0.1667
type: LocalParameter

meta ADP
initial amount: NaN
name: ADP
is: CHEBI:16761
is: SBO:0000247
in compartment: meta cell
type: Species
is: C00008
has only substance units: false
constant: false
boundary condition: false
initial concentration: 1.29

http://identifiers.org/biomodels.db/MODEL1303260007#a45ba910_8f94_4643_8b6b_376397e11a8d
value: 0.0106
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_0c54cafc_59c9_4cb4_99ff_db6316d8c2db
stoichiometry: 1.0
species: meta P2G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_0e4c81c6_f296_4a49_916d_d35b30a33b96
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

MODEL1303260007
species: meta UGP1
species: meta F26bP
reaction: meta HXK HXK2
species: meta SUC
species: meta GLY
reaction: meta PGI
reaction: meta succinate branch
species: meta P3G
initial assignment: MODEL1303260007#
species: meta ENO1
reaction: meta HXK GLK1
species: meta FBA1
species: meta GLC
reaction: meta TPI
reaction: meta TDH
species: meta AcAld
species: meta CDC19
reaction: meta GPP
species: meta ENO2
name: reversible michaelis-menten: ordered uni-bi
species: meta ADH5
species: meta HOR2
species: meta PGI1
notes: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 07 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran Smallbone, Hanan L. Messiha, Kathleen M. Carroll, Catherine L. Winder, Naglis Malys, Warwick B. Dunn, Ettore Murabito, Neil Swainston, Joseph O. Dada, Farid Khan, Pınar Pir, Evangelos Simeonidis, Irena Spasić, Jill Wishart, Dieter Weichart, Neil W. Hayes, Daniel Jameson, David S. Broomhead, Stephen G. Oliver, Simon J. Gaskell, John E.G. McCarthy, Norman W. Paton, Hans V. Westerhoff, Douglas B. Kell, Pedro Mendes FEBS Letters (in press) Abstract: We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought. This model is hosted on BioModels Database and identified by: MODEL1303260007 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more …
reaction: meta ENO
reaction: meta FBA
species: meta AMP
area units: area
species: meta P2G
reaction: meta AK
name: facilitated diffusion: symmetrical carrier
species: meta PEP
reaction: meta PGK
is: http://identifiers.org/taxonomy/4932
species: meta ACE
name: reversible michaelis-menten: one substrate, one product
reaction: meta PFK
reaction: meta ADH
species: meta TDH2
name: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 07
type: SBMLModel
species: meta PFK2
species: meta G6P
reaction: meta PGM
reaction: meta GPM
reaction: meta GPD
length unit: length
species: meta TDH3
name: irreversible mass action
species: meta TPS2
species: meta GAP
species: meta PDC5
reaction: meta PDC
species: meta GLCx
species: meta UDP
species: meta RHR2
species: meta ADP
species: meta UDG
species: meta DHAP
species: meta PDC6
compartment: meta cell
reaction: meta UGP
species: meta NADH
species: meta PDC1
species: meta ATP
name: irreversible michaelis-menten: one substrate, no product
species: meta TDH1
name: reversible michaelis-menten: ordered bi-bi
species: meta EtOH
species: meta NAD
species: meta PYR
species: meta GPD2
reaction: meta TPS
curated: false
name: irreversible michaelis-menten: two substrates, no products
reaction: meta PYK
species: meta TPS1
species: meta HXK1
reaction: meta HXT
reaction: meta ATPase

http://identifiers.org/biomodels.db/MODEL1303260007#aacaf310_3694_47b9_b015_babff2454793
value: 0.65
type: LocalParameter

meta G6P
in compartment: meta cell
has only substance units: false
type: Species
constant: false
is: CHEBI:17665
name: glucose 6-phosphate
is: SBO:0000247
initial amount: NaN
boundary condition: false
initial concentration: 0.193120800911304
is: C00668

http://identifiers.org/biomodels.db/MODEL1303260007#_25103714_ed33_4200_bd08_137e84dbbe17
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_85562ec2_0f0a_4c61_ae68_a155b168cfc5
value: 0.023
type: LocalParameter

meta UGP1
is: SBO:0000252
is: P32861
has only substance units: false
constant: true
name: UGP1
boundary condition: true
in compartment: meta cell
type: Species
is encoded by: S000001518
initial amount: NaN
initial concentration: 0.00155052854965178

meta HXT
modifier: MODEL1303260007#
type: Reaction
fast: false
name: glucose transport
is: SBO:0000185
reversible: true
is version of: GO:0015758

meta AK
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.7.4.3
reversible: true
fast: false
is: R00127
name: adenylate kinase
type: Reaction
modifier: MODEL1303260007#
is version of: GO:0004017

meta GAP
initial amount: NaN
constant: false
is: CHEBI:29052
initial concentration: 0.0789727571926259
name: glyceraldehyde 3-phosphate
type: Species
is: C00118
boundary condition: false
is: SBO:0000247
in compartment: meta cell
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260007#_95293e3f_ecd4_46c5_88d7_81cbf87fa3ca
units: dimensionless
value: 0.0845
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_3ea77906_e60d_4930_91a4_2a26a9684f67
value: 0.08
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#a4dea6d9_f5ec_4e4f_a71f_ee1176603282
value: 16.6666666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#a17e0823_e7ff_4249_bae8_cae6594ea113
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta P2G
has only substance units: false
is: CHEBI:17835
boundary condition: false
type: Species
initial amount: NaN
name: 2-phosphoglycerate
in compartment: meta cell
is: SBO:0000247
constant: false
initial concentration: 0.0169344770274836
is: C00631

http://identifiers.org/biomodels.db/MODEL1303260007#_1f074531_e992_4d8b_ba76_c5df15e18092
value: 10.0
type: LocalParameter

meta TDH
is version of: GO:0004365
name: glyceraldehyde phosphate dehydrogenase
modifier: MODEL1303260007#
is: SBO:0000176
is: R01061
type: Reaction
is version of: http://identifiers.org/ec-code/1.2.1.12
reversible: true
fast: false

http://identifiers.org/biomodels.db/MODEL1303260007#a19ff860_1a80_44f6_bd81_0dd87a62d7ce
value: 17.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_84c8c715_e47f_4139_9fb6_3b2e6d4185b0
value: 0.54
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#a754a932_502e_4196_9d98_5b6845ffe2ef
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_1e504914_12ff_4521_973b_b296a5432efe
value: 0.1
type: LocalParameter

meta ADH5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00106249605621922
initial amount: NaN
in compartment: meta cell
name: ADH5
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_994d8e4b_d92d_464e_aa73_71e9f4bea4d2
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260007#_438fe47b_6e38_4c89_9ddb_2017faf9a568
units: dimensionless
value: 10000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_13f66817_3c3b_4d19_9783_bf32660a367c
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_2fd027d7_3cfd_4c5e_b9c9_266d64480ce6
units: dimensionless
value: 14492.7536231884
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#d514e766_6c5e_457e_8210_f5c1ea416bbd
value: 0.883333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_90bce4ef_12a1_48e7_b6e2_4fcdb03897cb
value: 0.886
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_9eea7725_f586_4c4c_81ea_bd05fe07f075
value: 17.6
type: LocalParameter

meta AMP
initial concentration: 0.44
is: SBO:0000247
is: CHEBI:16027
is: C00020
constant: false
initial amount: NaN
has only substance units: false
type: Species
boundary condition: true
name: AMP
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260007#_6c57c57d_6d7d_4a85_a502_104f3e10daa7
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#cde336e0_4cef_4d48_ab1c_9591012d4f85
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#a61dd466_e545_4366_ab05_cd09a76b63d8
value: 6.82E-4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_7b6e6507_7726_4f72_8979_77a48fdbb4bd
value: 0.2
type: LocalParameter

meta GPD2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.98351416606057E-4
initial amount: NaN
in compartment: meta cell
name: GPD2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#c7bdf90d_d788_45aa_a9cd_eb98e4bbe291
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

meta F26bP
initial concentration: 0.003
constant: true
initial amount: NaN
has only substance units: false
name: fructose 2,6-bisphosphate
boundary condition: true
is: SBO:0000247
in compartment: meta cell
is: C00665
type: Species
is: CHEBI:28602

http://identifiers.org/biomodels.db/MODEL1303260007#_52561bc8_fa04_4557_8604_804726d302d0
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#c4ac8c69_bf8e_4fec_8b20_93bf6e2be236
value: 4.33
type: LocalParameter

meta CDC19
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.512097526792801
initial amount: NaN
in compartment: meta cell
name: CDC19
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_50666a83_c80a_4b8b_a69f_05dead056390
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#_5ace23e2_3994_4273_811a_ac4c9ceec09c
value: 30.0
type: LocalParameter

meta acetate branch
fast: false
type: Reaction
modifier: MODEL1303260007#
is: SBO:0000176
is version of: GO:0006105
name: acetate branch
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260007#_3cf2be32_7e15_4dd4_8b92_b21954be1efa
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#e97cccd4_b917_42fa_9cb0_b6c81403c833
units: dimensionless
value: 0.91
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_1c16b816_0a1d_456a_9b9a_00ff933dac63
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_247c8185_0b72_49d6_b671_9f7127c25926
stoichiometry: 3.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#cae1fa57_d7a7_4166_be52_757d22227fce
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#e6c69bbf_3ac9_458a_9246_cfa6c65afd4d
value: 2.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#d981d589_0fd7_4164_bc1b_461d111fe780
stoichiometry: 1.0
species: meta GLCx
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_406f7768_75a5_4b3f_9998_5faeb184e88f
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#b9a53b49_a1af_4d89_a558_fd196d5a0645
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta PYK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00151748381804475
initial amount: NaN
in compartment: meta cell
name: PYK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_4693c189_a705_4586_8d70_4fb6894e5ba4
name: per mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260007#_5f6a1750_d936_4d50_9dd6_78f1933549b9
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_71a5f1b2_6010_4c17_a371_df14ca3d7d20
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

meta ADH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0409771277320022
initial amount: NaN
in compartment: meta cell
name: ADH1
type: Species

meta DHAP
initial amount: NaN
in compartment: meta cell
initial concentration: 0.290344213186674
is: C00111
constant: false
name: dihydroxyacetone phosphate
is: SBO:0000247
boundary condition: false
is: CHEBI:16108
type: Species
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260007#_66d07921_b9f0_4311_aa01_7631bc2216c7
value: 2.0
type: LocalParameter

meta ATP
is: C00002
has only substance units: false
constant: false
boundary condition: false
type: Species
initial amount: NaN
is: CHEBI:15422
in compartment: meta cell
initial concentration: 4.29
is: SBO:0000247
name: ATP

http://identifiers.org/biomodels.db/MODEL1303260007#_14f681cd_1015_4eb7_80b3_5b1d551c89e0
value: 0.00554339592436782
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_54283e6c_c534_42a1_9025_3b2aa1649aba
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

meta GLY
type: Species
is: C00116
in compartment: meta cell
boundary condition: true
constant: true
has only substance units: false
is: CHEBI:17754
is: SBO:0000247
initial concentration: 0.15
initial amount: NaN
name: glycerol

meta PEP
initial concentration: 0.152501353339511
in compartment: meta cell
initial amount: NaN
boundary condition: false
constant: false
is: SBO:0000247
has only substance units: false
name: phosphoenolpyruvate
is: C00074
is: CHEBI:18021
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#d980a108_b1d8_4e87_abe1_5334a1c4b296
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_1decd09d_e354_4085_9790_e3a50b24c71a
stoichiometry: 1.0
species: meta BPG
type: SpeciesReference

meta succinate branch
is: SBO:0000176
reversible: false
modifier: MODEL1303260007#
name: succinate branch
type: Reaction
is version of: GO:0006105
fast: false

http://identifiers.org/biomodels.db/MODEL1303260007#_62fe3457_7468_45e8_8be1_e5e37e780a96
value: 0.05
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_7ba41632_e312_44a4_b824_4665c538ab68
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260007#_8c040923_5a1d_4801_839a_c4971ae07667
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_5643c57c_dc9d_4867_9be6_e748f1b87728
constant: true
units: dimensionless
value: 38.8857
type: Parameter

meta HXK HXK2
name: hexokinase [HXK2]
reversible: true
fast: false
is: SBO:0000176
modifier: MODEL1303260007#
is: R02848
is version of: http://identifiers.org/ec-code/2.7.1.1
type: Reaction
is version of: GO:0004396

http://identifiers.org/biomodels.db/MODEL1303260007#_2917c798_8609_4598_86c3_1bda71120b6f
value: 1.13333333333333
type: LocalParameter

meta BPG
initial concentration: 7.36873499865602E-4
initial amount: NaN
boundary condition: false
has only substance units: false
is: C00236
constant: false
type: Species
name: 1,3-bisphosphoglycerate
in compartment: meta cell
is: SBO:0000247
is: CHEBI:16001

http://identifiers.org/biomodels.db/MODEL1303260007#_0cb3913c_d6b8_4a4a_bfde_bb983f6b764b
value: 0.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_91c18281_034e_42dd_bd75_d63eec40507f
value: 0.108333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#ad5542a1_82d2_4a1e_9bdf_aed340e91ba3
constant: true
units: litre
value: 2.0E-14
name: volume
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260007#_95b1c685_3abf_4a57_ada0_5edad8f24728
value: 1.57816666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_4571035e_bdf3_4a0a_b4cc_bac4a99ef548
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

meta ACE
initial amount: NaN
has only substance units: false
type: Species
initial concentration: 55.7500633495734
boundary condition: true
constant: true
is: SBO:0000247
in compartment: meta cell
is: CHEBI:30089
name: acetate

http://identifiers.org/biomodels.db/MODEL1303260007#e138838f_3180_416d_937b_4fadbf414125
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#_6e455fb8_5afc_4336_8d6f_3ac1438fcdd9
value: 0.09
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#e2777064_81ac_42e7_86f3_407dbde591c1
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#cb94681a_9bdf_4185_b379_29dbfbd5f3d1
value: 0.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#affa1255_0814_4e54_b5ad_c4779c6ae937
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

meta GPM
is: SBO:0000176
reversible: true
is: R01518
is version of: http://identifiers.org/ec-code/5.4.2.1
is version of: GO:0004619
modifier: MODEL1303260007#
name: phosphoglyceromutase
fast: false
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260007#_842941b2_ff0e_43fb_bccd_b170171641f7
value: 1.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#af4557ea_8093_4f79_ae91_96bd30f76581
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#d05cb9a9_2f50_40b2_9672_bd6f517c5a7a
value: 0.32
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_0f3b1d7e_5019_4a5b_a198_ee20e6d2b527
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#ae46dcca_35e5_4991_912b_a31795ac646a
value: 0.73
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#caeece8c_3b9f_4914_808a_9882cb39fa61
value: 4.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_65af0ec8_abb8_40a7_98cc_8439bf3849d2
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

meta ADH
is version of: GO:0004022
modifier: MODEL1303260007#
reversible: true
fast: false
name: alcohol dehydrogenase
is: SBO:0000176
type: Reaction
is version of: http://identifiers.org/ec-code/1.1.1.1
is: R00754

meta G1P
boundary condition: false
has only substance units: false
in compartment: meta cell
is: SBO:0000247
is: CHEBI:16077
constant: false
name: glucose 1-phosphate
initial amount: NaN
initial concentration: 0.13481212658623
type: Species

meta UDG
initial concentration: 0.467246194874247
has only substance units: false
is: SBO:0000247
type: Species
constant: false
initial amount: NaN
in compartment: meta cell
boundary condition: true
name: UDP glucose
is: CHEBI:18066

http://identifiers.org/biomodels.db/MODEL1303260007#b029cb44_ac52_4fad_bb00_da28f2e05d55
name: mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260007#c68356ba_e242_49bd_9099_7a6387ce3d15
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_99cd0b8c_609b_4955_98f8_945f47a74c69
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260007#_6bb7abfe_1fea_4211_8ed7_4f45bdd5660e
name: per mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260007#_16feb4ee_33a2_466c_b15e_dc99f953a74c
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#b484c4f5_4b76_4aee_8b71_c2e076d71e85
value: 0.111
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#b7a4a94a_e2b5_43ea_a297_13d58e78ead1
value: 111.334973497906
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_8919e935_f430_45f9_98f6_6275772aa497
units: dimensionless
value: 0.66
type: LocalParameter

meta GPD1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00170877794272468
initial amount: NaN
in compartment: meta cell
name: GPD1
type: Species

meta UTP
has only substance units: false
is: CHEBI:46398
initial concentration: 0.6491
is: SBO:0000247
boundary condition: false
name: UTP
in compartment: meta cell
initial amount: NaN
constant: false
type: Species

meta HXK HXK1
is: SBO:0000176
modifier: MODEL1303260007#
is: R02848
is version of: GO:0004396
fast: false
name: hexokinase [HXK1]
type: Reaction
reversible: true
is version of: http://identifiers.org/ec-code/2.7.1.1

meta NAD
name: NAD
in compartment: meta cell
initial concentration: 1.50329030201531
constant: false
is: CHEBI:15846
is: C00003
type: Species
boundary condition: false
has only substance units: false
initial amount: NaN
is: SBO:0000247

meta GPM1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.182500074724267
initial amount: NaN
in compartment: meta cell
name: GPM1
type: Species

meta NADH
in compartment: meta cell
is: CHEBI:16908
type: Species
initial concentration: 0.0867096979846952
boundary condition: true
name: NADH
has only substance units: false
initial amount: NaN
is: SBO:0000247
is: C00004
constant: false

meta GPP
name: glycerol 3-phosphatase
type: Reaction
fast: false
is: R00841
is: SBO:0000176
modifier: MODEL1303260007#
is: http://identifiers.org/ec-code/3.1.3.21
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260007#_6c4c06b5_6851_4c94_8387_5c3de35898af
value: 0.5
type: LocalParameter

meta TRH
is: C01083
type: Species
is: SBO:0000247
initial concentration: 0.00384697134241316
in compartment: meta cell
boundary condition: true
has only substance units: false
is: CHEBI:16551
constant: true
name: trehalose
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260007#_0fd7f121_7d86_4203_a2a2_2fa029ac0437
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_046f7752_b1c0_4c70_9a4a_964ac87a7d33
value: 0.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_8bac45a0_a8e6_4cc5_8079_28c5314ad3b2
units: dimensionless
value: 0.45
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#e82c4803_2d2b_41e1_9616_9e530a29e530
value: 90.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#e88d9ba5_d8c7_4910_a1c1_eab41b9b428d
name: mM
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260007#_2839d9de_1fb7_465e_a27e_a2508f4aff2d
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#d1835d5d_ba05_48c2_b6a1_f21b0b26d5ce
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta TPS2
has only substance units: false
initial concentration: 6.64962953368736E-4
is: SBO:0000252
name: TPS2
type: Species
is encoded by: S000002481
in compartment: meta cell
boundary condition: true
is: P31688
constant: true
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260007#_6a8b61e9_ace7_4dfd_ad18_0ca5a7394daa
value: 0.11
type: LocalParameter

meta HXK GLK1
reversible: true
type: Reaction
is: R02848
modifier: MODEL1303260007#
is version of: http://identifiers.org/ec-code/2.7.1.1
is: SBO:0000176
name: hexokinase [GLK1]
fast: false
is version of: GO:0004396

meta PGK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0644142281647388
initial amount: NaN
in compartment: meta cell
name: PGK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_3b744ab4_1efe_454d_8fc4_5340dfa3db8c
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

meta TDH3
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.05110118662137
initial amount: NaN
in compartment: meta cell
name: TDH3
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_9b2f4058_3e6f_43e2_960a_2ba1f506f764
value: 3.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#f001d0aa_03de_41f8_9d80_559741b3b79e
units: dimensionless
value: 5.12
type: LocalParameter

meta AcAld
is: C00084
has only substance units: false
initial concentration: 0.178140579850657
name: acetaldehyde
type: Species
constant: false
in compartment: meta cell
is: SBO:0000247
is: CHEBI:15343
initial amount: NaN
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1303260007#_9a458db7_75d1_4935_ae54_8da9028cb0fd
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#b0ab0a61_1b99_494b_9576_43b1e78285d4
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#a00e1244_321c_4a7c_83ac_344f4381fd89
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_5a6e3a10_0a88_48d8_a25b_30c94c0f8a26
constant: true
value: 6.02
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260007#_323ab58e_adf7_4d5d_a943_4203cee15259
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_070226cf_9884_424c_b19f_1a2cef92f80a
value: 1.4
type: LocalParameter

meta PGI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0345726768225249
initial amount: NaN
in compartment: meta cell
name: PGI1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_797b4f75_aaa6_487d_85a3_1d161ba6dd41
units: dimensionless
value: 0.00533412710224736
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_504f5fe8_fd80_4fa2_9734_d5b9bfe5f8cf
value: 0.00590833333333333
type: LocalParameter

meta TPS1
is: SBO:0000252
constant: true
is encoded by: S000000330
type: Species
name: TPS1
boundary condition: true
has only substance units: false
initial concentration: 8.48120435592663E-4
is: Q00764
initial amount: NaN
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260007#_24e25602_21e2_4078_8548_76362e78e674
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

meta TDH2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: meta cell
name: TDH2
type: Species

meta UGP
is: SBO:0000176
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.7.9
name: UDP glucose phosphorylase
modifier: MODEL1303260007#
fast: false
reversible: false

meta extracellular
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260007#d88402a6_0f0e_46a1_9fbf_d1618ef3d1b8
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_06c0a80e_5382_4433_910b_8dd6dac0d4b9
units: dimensionless
value: 0.19
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#c1f400e3_42a7_4fe5_8159_b383b98a9a21
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta TDH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.087716160700349
initial amount: NaN
in compartment: meta cell
name: TDH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#c40aca33_f683_465e_9d9d_f594dca81dbe
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260007#_57e41bab_d22c_4162_9512_408d72f22a99
value: 0.53
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#_261b1add_12ac_4f72_bf4c_54e91957f7bc
value: 0.71
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260007#b5eb1be7_8113_4b37_b3f3_d94ac63a6969
value: 0.23
type: LocalParameter

meta GLC
has only substance units: false
initial amount: NaN
boundary condition: false
is: CHEBI:4167
is: C00031
constant: false
type: Species
in compartment: meta cell
is: SBO:0000247
initial concentration: 1.5700004483456
name: glucose

meta TPI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.073589454911377
initial amount: NaN
in compartment: meta cell
name: TPI1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260007#_30e53c76_ae84_4277_a35d_ef2fa2377c91
value: 0.3
type: LocalParameter

orgname: University of Manchester

W3 CDTF: Sun Nov 09 00:00:00 GMT 2008

W3 CDTF: Wed Nov 14 14:34:55 GMT 2012

n:
  given: Kieran
  family: Smallbone