http://identifiers.org/biomodels.db/MODEL1303260006#b6208a72_04f9_4ebd_a423_189b10b46b6c
stoichiometry: 1.0
species: meta UDP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_69435066_bb0b_4330_9cd7_c6758285a534
stoichiometry: 1.0
species: meta F6P
type: SpeciesReference

meta PGK
name: 3-phosphoglycerate kinase
is version of: http://identifiers.org/ec-code/2.7.2.3
is version of: GO:0004618
reversible: true
modifier: MODEL1303260006#
is: R01512
is: SBO:0000176
type: Reaction
fast: false

http://identifiers.org/biomodels.db/MODEL1303260006#_44c3fc5c_341f_4f52_9fc4_2a65516298cc
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#_48b37bc7_2654_4b67_8347_956fc30102c0
constant: true
units: dimensionless
value: 2000.0
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#fa2203a7_686d_4870_851c_ce1888836c99
value: 0.23
type: LocalParameter

meta PFK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0116962574765781
initial amount: NaN
in compartment: meta cell
name: PFK1
type: Species

meta UTP
is: CHEBI:46398
name: UTP
has only substance units: false
initial concentration: 0.6491
initial amount: NaN
is: SBO:0000247
type: Species
in compartment: meta cell
constant: false
boundary condition: false

http://identifiers.org/biomodels.db/MODEL1303260006#_4a23a754_9b0f_40ad_94bc_11139750ad07
value: 0.293
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_2702bb37_612e_4e4d_834c_e176f8fe0e78
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#bfbba79b_c61a_4e15_a224_2628e9487043
value: 111.334973497906
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_0f386f8e_2dc5_4e65_8e34_7995ff011b37
value: 0.53
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#e94265ca_b775_48d8_9e16_8531d9f8f07b
units: dimensionless
value: 0.45
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_1091ed5c_df95_4cff_99b4_fd3e55c1f3ae
value: 14.2966666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_8458098e_dc29_4916_b2a3_4c36f322aedc
stoichiometry: 1.0
species: meta GLY
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_886307ee_bea3_4295_88be_09bf55977078
value: 3.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_422d562c_dd9a_4ffa_8cdc_673e43b75d3a
exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#f3ca4e1f_c84e_4317_9f63_9d371c162919
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta GLC
boundary condition: false
initial concentration: 1.5700004483456
name: glucose
has only substance units: false
type: Species
initial amount: NaN
is: CHEBI:4167
is: C00031
is: SBO:0000247
constant: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260006#_8af8012b_d2dd_44be_8fd6_b03e9de9ae75
value: 0.5
type: LocalParameter

meta ATPase
reversible: false
fast: false
modifier: MODEL1303260006#
type: Reaction
is: SBO:0000176
is version of: GO:0016887
name: ATPase

http://identifiers.org/biomodels.db/MODEL1303260006#db7ed1d6_156a_4a69_b94c_a61b1e11b6b7
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#_8ed47709_1ea1_4df2_bfd9_1ef35190c0b9
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_45352faf_dd64_445c_a928_63a3f631e7b6
value: 1.13333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_243e7f4f_13ad_4929_8405_3d5ebfbd9c57
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#b944d770_3c8b_45de_bc2b_51000ddd7bf1
units: dimensionless
value: 0.0845
type: LocalParameter

meta PGI
modifier: MODEL1303260006#
type: Reaction
is version of: http://identifiers.org/ec-code/5.3.1.9
fast: false
reversible: true
is version of: GO:0004347
is: R00771
is: SBO:0000176
name: phosphoglucose isomerase

http://identifiers.org/biomodels.db/MODEL1303260006#_8cebe9e8_822d_4282_891d_c6bfebfa5d79
value: 0.11
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_60c386a7_2a2b_4f86_983e_e03db31caeb7
value: 0.32
type: LocalParameter

meta GPD
is: SBO:0000176
fast: false
reversible: true
modifier: MODEL1303260006#
name: glycerol 3-phosphate dehydrogenase
is: R00842
is: http://identifiers.org/ec-code/1.1.1.94
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260006#_693e7d85_58d4_49fd_b52e_ddd9c8d23417
value: 0.783333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_3fc6ede7_dcf1_4862_ad09_ad47964cf455
value: 259.220125786164
type: LocalParameter

meta PFK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00975915538330228
initial amount: NaN
in compartment: meta cell
name: PFK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_8bfc7b5f_6d8f_4314_ac62_840a55be69ad
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#d18d30b8_1b9a_42aa_9330_019eef0a3deb
value: 0.65
type: LocalParameter

meta AMP
initial amount: NaN
name: AMP
boundary condition: true
constant: false
has only substance units: false
is: C00020
is: SBO:0000247
initial concentration: 0.44
is: CHEBI:16027
type: Species
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260006#_816b4c6f_af4e_49e7_bb5a_5068da43f1bf
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#b78de593_244e_49b6_b415_b31119700e1a
value: 1.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#daff2f05_1e9b_4caa_a2c5_2c74b3591c71
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#f74fa7b1_178e_4e75_a905_23bb9925c1a4
value: 1.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_9e8f21f1_835f_4242_9aaa_ba79a041ea35
units: dimensionless
value: 0.29
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#fdea4393_7ac6_49b2_a2f4_288ff2cfc79c
value: 0.3
type: LocalParameter

meta G1P
has only substance units: false
is: SBO:0000247
initial amount: NaN
in compartment: meta cell
initial concentration: 0.13481212658623
boundary condition: false
name: glucose 1-phosphate
is: CHEBI:16077
constant: false
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#ba2bde9f_97d6_40c6_9d55_c3959381b33f
value: 0.08
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#d1786acd_94b1_44c6_9dbf_f0f28988e110
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

meta F6P
name: fructose 6-phosphate
is: C05345
type: Species
initial concentration: 0.0588603054728053
in compartment: meta cell
constant: false
boundary condition: false
is: CHEBI:16084
is: SBO:0000247
has only substance units: false
initial amount: NaN

meta ADP
initial amount: NaN
in compartment: meta cell
has only substance units: false
name: ADP
is: CHEBI:16761
is: C00008
boundary condition: false
constant: false
is: SBO:0000247
type: Species
initial concentration: 1.29

http://identifiers.org/biomodels.db/MODEL1303260006#e328d5a9_71fe_4fc8_b1fd_c15b75be09d5
value: 4.8
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_1a451dca_1f24_46c2_b7d0_b3a7dae124c3
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#f3749549_c525_443c_a250_fbd395802a35
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#_813f322f_0c9b_473f_a2c6_78c58a6c44c9
constant: true
value: 6.022140000000001E20
name: Avogadro constant
type: Parameter

meta ENO1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.171592988538958
initial amount: NaN
in compartment: meta cell
name: ENO1
type: Species

meta TPI
fast: false
type: Reaction
is: SBO:0000176
is version of: GO:0004807
is: R01015
reversible: true
name: triosephosphate isomerase
modifier: MODEL1303260006#
is version of: http://identifiers.org/ec-code/5.3.1.1

http://identifiers.org/biomodels.db/MODEL1303260006#_6b34fd22_798c_4e55_bf4c_dd847f728c0b
value: 0.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_979367d1_562b_4ae1_98fe_1f02bd63cbef
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#_55d7f4f3_d58d_4252_b474_9d69e5fe0527
stoichiometry: 1.0
species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#fe68582f_b17d_4ec8_ad3d_cc571ff5d43c
stoichiometry: 1.0
species: meta UTP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_59759434_df4d_4822_ac0a_9eeb3644ca9f
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta ENO2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.493611573294543
initial amount: NaN
in compartment: meta cell
name: ENO2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_3bfba4ef_7d4a_44cd_b4ad_11d8d6f4915d
stoichiometry: 1.0
species: meta TRH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#fab1289a_f8b9_483e_8aff_bfa3438395ef
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

meta ATP
name: ATP
is: SBO:0000247
type: Species
initial amount: NaN
boundary condition: false
constant: false
is: CHEBI:15422
is: C00002
in compartment: meta cell
initial concentration: 4.29
has only substance units: false

http://identifiers.org/biomodels.db/MODEL1303260006#_1462653a_c43e_4cc8_9807_24d37ae7f153
stoichiometry: 2.0
species: meta AcAld
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_93ee7858_22b4_4b1c_815b_f6d9d44bc38b
value: 0.003
type: LocalParameter

meta CDC19
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.512097526792801
initial amount: NaN
in compartment: meta cell
name: CDC19
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#ec469ec1_354e_4eb4_8b17_b0915e040a42
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#e9fca824_0178_42c8_9592_ef047d1fc853
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#f74ebaff_7fe7_4510_885d_fce133bd68ce
stoichiometry: 1.0
species: meta EtOH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_8f8095aa_48f3_4258_8ca1_639b72f38ba6
value: 0.92
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_8ee23a5c_2fa2_4ef7_a9e9_36260dd0d00b
value: 209.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_792a7f9e_de8d_4f2b_9c41_b5e0f5c29fcb
name: mM
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260006#_47da84f6_4681_41d4_8291_6dbd760652b6
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_85823fb8_43e1_4aab_86b7_d896d241fb6a
value: 19.2
type: LocalParameter

meta PGK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0644142281647388
initial amount: NaN
in compartment: meta cell
name: PGK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_4bbab024_8b01_4ec6_af07_2bd036c0034a
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

meta UGP
is version of: http://identifiers.org/ec-code/2.7.7.9
name: UDP glucose phosphorylase
type: Reaction
reversible: false
fast: false
is: SBO:0000176
modifier: MODEL1303260006#

http://identifiers.org/biomodels.db/MODEL1303260006#_582667ad_3686_4ed0_9685_116cfedcbe6d
stoichiometry: 1.0
species: meta GLCx
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_54dcdec4_d01e_49f0_9c85_c259ef9ceaec
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_69b74db1_1af8_4600_b357_53856802c97b
value: 0.15
type: LocalParameter

meta PGI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0345726768225249
initial amount: NaN
in compartment: meta cell
name: PGI1
type: Species

meta UDP
name: UDP
initial amount: NaN
has only substance units: false
is: CHEBI:17659
is: SBO:0000247
boundary condition: false
type: Species
constant: false
initial concentration: 0.2815
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260006#_8e496418_2c92_49f5_b283_bf661fae30cd
stoichiometry: 1.0
species: meta UDG
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_3bb1da2e_f32a_4d72_9b57_8cc38efd7bed
units: dimensionless
value: 0.1667
type: LocalParameter

meta F16bP
initial amount: NaN
boundary condition: false
has only substance units: false
type: Species
is: SBO:0000247
initial concentration: 1.14580464751733
is: C05378
is: CHEBI:28013
in compartment: meta cell
name: fructose 1,6-bisphosphate
constant: false

http://identifiers.org/biomodels.db/MODEL1303260006#aa062c8c_a203_4a7d_877f_31e1eb3a9732
value: 0.93
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#c7d70b95_e77f_42e9_af15_8fe50475a12b
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_2e3c5727_2790_4931_8848_81916a3108cb
value: 3.5
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_1ee64b3e_7dfa_495d_ac11_d8886c1ec4f1
value: 0.14
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#e6339a1a_c536_4bd7_8863_c353638181da
value: 0.00345026988011002
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_289c6a51_33b1_43cf_8607_8b99af5f2e09
stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_94403e6c_bbd1_4565_b2d8_f8655efc263e
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_6b37afcd_5dcc_483a_af42_81813e452d95
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

meta HXT
name: glucose transport
modifier: MODEL1303260006#
is: SBO:0000185
type: Reaction
reversible: true
is version of: GO:0015758
fast: false

meta FBA
is: R01068
name: fructosebisphosphate aldolase
is version of: http://identifiers.org/ec-code/4.1.2.13
type: Reaction
modifier: MODEL1303260006#
is: SBO:0000176
fast: false
is version of: GO:0004332
reversible: true

http://identifiers.org/biomodels.db/MODEL1303260006#_94b19caa_b5d9_4968_a526_3262ec6a7663
value: 0.9
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_4861c26f_3d7d_4809_a1c2_b800e272f8ab
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_54dcac4b_c5d2_48d4_a0c4_9a40cf45f2a8
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_47419fae_9cdd_4f03_a68f_592cb09664a3
value: 21.0
type: LocalParameter

meta GPM
is: SBO:0000176
type: Reaction
modifier: MODEL1303260006#
is: R01518
is version of: GO:0004619
is version of: http://identifiers.org/ec-code/5.4.2.1
name: phosphoglyceromutase
fast: false
reversible: true

http://identifiers.org/biomodels.db/MODEL1303260006#_71d33291_c125_4ad4_b77c_fbfa0283ea6a
exponent: 1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#_377afd28_4b3f_4a14_a050_9e89784ee5c7
value: 17.0
type: LocalParameter

meta AcAld
is: SBO:0000247
has only substance units: false
is: C00084
type: Species
boundary condition: false
in compartment: meta cell
constant: false
initial concentration: 0.178140579850657
name: acetaldehyde
is: CHEBI:15343
initial amount: NaN

http://identifiers.org/biomodels.db/MODEL1303260006#f6269bdb_e929_4e13_b6ea_23758e51ddde
reversible: false
type: Reaction
modifier: MODEL1303260006#
fast: false
name: UDP to UTP pseudoreaction
is: SBO:0000176

http://identifiers.org/biomodels.db/MODEL1303260006#bd7e8f15_f775_457c_9602_ed9f2d5bc93e
value: 0.04
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_419d1bca_cfc8_4a15_8dfc_7607be573cf4
value: 2.4
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_7aef3337_ac7a_41ea_a9f5_42f153a17142
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta HOR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0013683673909939
initial amount: NaN
in compartment: meta cell
name: HOR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_41c30526_05fd_478f_a744_c4ec159204ec
stoichiometry: 1.0
species: meta NAD
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_966b166d_9732_4778_8db0_3f6a4a2f6b8a
value: 0.031
type: LocalParameter

meta RHR2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0127951193429578
initial amount: NaN
in compartment: meta cell
name: RHR2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#f32992cf_ca98_4449_819b_6d466cca3f8a
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

meta PFK
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.7.1.11
type: Reaction
modifier: MODEL1303260006#
fast: false
is: R00756
name: phosphofructokinase
is version of: GO:0003872
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260006#c7282995_3f67_4e56_b43c_de6e02c7cccf
name: per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260006#_83a81f4b_88c8_4843_8c9c_3b0f6b589342
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#ddd73c34_84be_4199_a42d_a04da909008d
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_866fc156_845b_4821_b48c_80bd6f16d9e3
value: 0.71
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_1020a2ee_2b57_43cb_8450_3d216d64ecff
stoichiometry: 1.0
species: meta DHAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#afcef751_5f74_4dfd_96e5_f9d07a6f687d
value: 10.0
type: LocalParameter

meta SUC
is: SBO:0000247
type: Species
name: succinate
initial concentration: 0.0
boundary condition: true
initial amount: NaN
in compartment: meta cell
constant: true
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http://identifiers.org/biomodels.db/MODEL1303260006#ceedb689_8dda_4dc2_88c4_cf623ad8298f
stoichiometry: 1.0
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type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_28d9e193_f4f3_48a7_a561_b42d1a6e575f
value: 16.6666666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_113cf19b_1c0d_4527_81b4_a50f76adb281
stoichiometry: 1.0
species: meta AcAld
type: SpeciesReference

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stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

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constant: true
value: 1.59
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#_5126d36b_28f2_4d8a_a05d_d69698a268b5
exponent: -1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#fea08840_bd58_4f6b_bfe4_7a7abb1f37b8
value: 30.0
type: LocalParameter

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exponent: -1.0
scale: -3
multipler: 1.0
kind: MOLE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#_06912549_5b97_4f1c_9d12_9dca5a3718e8
value: 0.09
type: LocalParameter

meta GAP
constant: false
type: Species
initial amount: NaN
boundary condition: false
has only substance units: false
initial concentration: 0.0789727571926259
is: SBO:0000247
is: C00118
in compartment: meta cell
name: glyceraldehyde 3-phosphate
is: CHEBI:29052

http://identifiers.org/biomodels.db/MODEL1303260006#_48407f6a_0edf_4a09_a6f9_488ae76dbf87
stoichiometry: 1.0
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type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_6beb5056_45dd_400f_a119_aef94dee1f37
value: 0.54
type: LocalParameter

meta HXK HXK2
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fast: false
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.7.1.1
reversible: true
modifier: MODEL1303260006#
is version of: GO:0004396
is: R02848
name: hexokinase [HXK2]

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stoichiometry: 1.0
species: meta UTP
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value: 0.23
type: LocalParameter

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value: 0.11
type: LocalParameter

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stoichiometry: 1.0
species: meta P2G
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meta PGM
type: Reaction
modifier: MODEL1303260006#
reversible: true
is version of: http://identifiers.org/ec-code/5.4.2.2
name: phosphoglucomutase
is: SBO:0000176
fast: false

http://identifiers.org/biomodels.db/MODEL1303260006#e063840d_5159_4b82_9427_1361ec4f026a
stoichiometry: 1.0
species: meta GAP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_05ddc8f4_4003_4617_965e_45d28468690a
value: 0.73
type: LocalParameter

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stoichiometry: 1.0
species: meta F6P
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stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

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value: 0.886
type: LocalParameter

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stoichiometry: 1.0
species: meta SUC
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http://identifiers.org/biomodels.db/MODEL1303260006#_6d0ca0e1_edb4_4ced_94e5_188c558c139b
units: dimensionless
value: 6500.0
type: LocalParameter

meta NAD
boundary condition: false
is: CHEBI:15846
type: Species
is: C00003
constant: false
is: SBO:0000247
in compartment: meta cell
name: NAD
has only substance units: false
initial concentration: 1.50329030201531
initial amount: NaN

meta HXK HXK1
name: hexokinase [HXK1]
type: Reaction
is: SBO:0000176
is version of: http://identifiers.org/ec-code/2.7.1.1
reversible: true
modifier: MODEL1303260006#
is version of: GO:0004396
is: R02848
fast: false

meta UDG
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boundary condition: true
is: CHEBI:18066
name: UDP glucose
has only substance units: false
initial amount: NaN
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is: SBO:0000247
initial concentration: 0.467246194874247

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stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta GPP
fast: false
reversible: false
name: glycerol 3-phosphatase
is: R00841
modifier: MODEL1303260006#
is: http://identifiers.org/ec-code/3.1.3.21
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260006#_0dbf971c_a71d_432e_82f7_6709836e339a
value: 0.75
type: LocalParameter

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units: dimensionless
value: 3200.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#d946c87c_bb3e_4890_b7b8_16ad069ed9c3
value: 17.6
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#c88a8dc1_e015_43e2_9931_37ad0a17a432
value: 0.02285
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_29f49ca7_f14b_4524_aef7_965e54c3353d
units: dimensionless
value: 3.0
type: LocalParameter

meta TDH2
is: SBO:0000252
constant: true
boundary condition: true
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initial concentration: 0.0
initial amount: NaN
in compartment: meta cell
name: TDH2
type: Species

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stoichiometry: 1.0
species: meta G3P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#b0309d46_883f_458a_b91d_86067e93eef1
value: 3.35
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_8ac52ef3_cb41_43bb_a39a_ad5faf7f6965
value: 30.0
type: LocalParameter

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value: 3.36
type: LocalParameter

meta DHAP
is: C00111
in compartment: meta cell
name: dihydroxyacetone phosphate
is: SBO:0000247
initial amount: NaN
boundary condition: false
constant: false
is: CHEBI:16108
type: Species
initial concentration: 0.290344213186674
has only substance units: false

MODEL1303260006
reaction: meta GPD
reaction: meta UGP
species: meta G6P
species: meta UGP1
name: min
reaction: meta PFK
species: meta HOR2
species: meta PYR
species: meta TDH2
reaction: meta PGM
species: meta PGI1
species: meta PDC5
name: reversible michaelis-menten: two noncompeting couples
name: reversible michaelis-menten: ordered bi-bi
species: meta SUC
species: meta DHAP
curated: false
species: meta HXK1
name: irreversible mass action
reaction: meta succinate branch
reaction: meta ENO
species: meta AMP
species: meta GPD2
species: meta PGM2
reaction: meta FBA
species: meta ADP
species: meta GLY
species: meta F26bP
species: meta TPI1
name: phosphofructokinase kinetics with Keq
species: meta F16bP
species: meta F6P
name: reversible michaelis-menten: one substrate, one product
species: meta PGM1
name: reversible michaelis-menten: ordered uni-bi
species: meta AcAld
species: meta G1P
reaction: meta PGI
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length unit: length
name: reversible mass action
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reaction: meta GPM
reaction: meta PYK
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notes: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 06 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran Smallbone, Hanan L. Messiha, Kathleen M. Carroll, Catherine L. Winder, Naglis Malys, Warwick B. Dunn, Ettore Murabito, Neil Swainston, Joseph O. Dada, Farid Khan, Pınar Pir, Evangelos Simeonidis, Irena Spasić, Jill Wishart, Dieter Weichart, Neil W. Hayes, Daniel Jameson, David S. Broomhead, Stephen G. Oliver, Simon J. Gaskell, John E.G. McCarthy, Norman W. Paton, Hans V. Westerhoff, Douglas B. Kell, Pedro Mendes FEBS Letters (in press) Abstract: We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought. This model is hosted on BioModels Database and identified by: MODEL1303260006 . To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models . To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more …
name: irreversible michaelis-menten: two substrates, no products
species: meta PGK1
species: meta TRH
species: meta ENO2
name: max
species: meta UDG
species: meta ATP
type: SBMLModel
species: meta TPS2
reaction: meta TPI
species: meta RHR2
species: meta ENO1
reaction: meta TPP
species: meta EtOH
reaction: meta HXT
name: Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 06
species: meta TDH1
species: meta UDP
species: meta PDC1
name: UGP kinetics
species: meta G3P
reaction: meta ADH
species: meta TPS1
species: meta T6P
reaction: meta AK
species: meta GPD1
compartment: meta extracellular
species: meta PFK2
species: meta GLCx
species: meta ADH5
species: meta TDH3
reaction: meta HXK HXK2
species: meta PYK2
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constant: true
units: dimensionless
value: 38.8857
type: Parameter

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value: 4.33
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meta TDH3
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constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.05110118662137
initial amount: NaN
in compartment: meta cell
name: TDH3
type: Species

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stoichiometry: 3.0
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stoichiometry: 2.0
species: meta ADP
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meta TPS
type: Reaction
name: T6P synthase
reversible: false
is: SBO:0000176
fast: false
is version of: http://identifiers.org/ec-code/2.4.1.15
modifier: MODEL1303260006#

meta P2G
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is: SBO:0000247
is: C00631
initial concentration: 0.0169344770274836
name: 2-phosphoglycerate
boundary condition: false
initial amount: NaN
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constant: false
type: Species
is: CHEBI:17835

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units: dimensionless
value: 0.00533412710224736
type: LocalParameter

meta AK
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modifier: MODEL1303260006#
is: R00127
fast: false
reversible: true
is version of: GO:0004017
is: SBO:0000176
type: Reaction

http://identifiers.org/biomodels.db/MODEL1303260006#_03d3c050_4fa9_4204_abd5_193a7c128f99
name: mmol
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260006#da316135_99b0_4243_8e0e_f4840c9164d7
units: dimensionless
value: 0.0174
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stoichiometry: 1.0
species: meta ATP
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meta TPS2
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is: P31688
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is: SBO:0000252
boundary condition: true
name: TPS2
initial concentration: 6.64962953368736E-4
has only substance units: false
in compartment: meta cell
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_708529f2_bdf4_4af4_8813_543c8c2067f5
value: 0.23
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#b250faeb_d0cf_40de_ace4_01a482c8cb0a
stoichiometry: 1.0
species: meta AcAld
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species: meta PYR
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#a5aa7902_b3ef_4726_96e3_d400f55ef814
value: 0.0721
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_0613d91d_ad44_40c4_94ae_b07fd29f2127
value: 0.237257345562943
type: LocalParameter

meta TDH
is: R01061
name: glyceraldehyde phosphate dehydrogenase
type: Reaction
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fast: false
is version of: GO:0004365
is version of: http://identifiers.org/ec-code/1.2.1.12
modifier: MODEL1303260006#
is: SBO:0000176

meta GLCx
is: C00031
type: Species
in compartment: meta extracellular
name: glucose
is: SBO:0000247
is: CHEBI:4167
has only substance units: false
constant: true
initial amount: NaN
initial concentration: 74.0
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1303260006#df4b9c72_2bf6_48ec_9d00_136571552ae3
units: dimensionless
value: 100.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_9f720ca9_a993_476b_b2d7_ce3f1844a761
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type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_91eba091_1bbe_4c1e_a9cb_e01b290d7526
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species: meta F16bP
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value: 1.4
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meta TDH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.087716160700349
initial amount: NaN
in compartment: meta cell
name: TDH1
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http://identifiers.org/biomodels.db/MODEL1303260006#_3aae5e82_0d8d_4a12_af28_d4fd240af5d3
value: 0.0035
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stoichiometry: 1.0
species: meta P3G
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http://identifiers.org/biomodels.db/MODEL1303260006#a22855b0_9e84_4268_8edc_7a7234bfc2d2
value: 0.17
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#e266bbd1_2e22_48cc_bd2f_f96801a7d322
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http://identifiers.org/biomodels.db/MODEL1303260006#_0444a7a1_adc7_44b9_bb2a_15f5b14cb802
value: 0.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_58414923_b530_496f_a265_3df2118e93a6
stoichiometry: 1.0
species: meta GLC
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stoichiometry: 1.0
species: meta ADP
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meta FBA1
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constant: true
boundary condition: true
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initial concentration: 0.0367018202831552
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http://identifiers.org/biomodels.db/MODEL1303260006#_9a5d18fc_8591_4a60_8158_4e8fbbb47d3a
value: 3.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#c180fff0_219d_42c1_a029_9eb59e8f3dc2
stoichiometry: 1.0
species: meta UDG
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stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#c5458cd7_fe2c_48bd_87f3_7ecf8ad1c7c8
value: 0.21
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#a4f9ba46_f86b_4000_b3a9_9997b76573fc
value: 0.00590833333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_515c3f7e_baf6_4198_9001_23a5a228cd8c
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_878f37e3_4906_4694_987c_f969b43ff663
stoichiometry: 1.0
species: meta T6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_91b30ef0_fd14_41fe_bcdd_da4ee5442c2b
value: 0.3
type: LocalParameter

meta PYR
has only substance units: false
boundary condition: false
is: SBO:0000247
is: CHEBI:15361
initial amount: NaN
in compartment: meta cell
type: Species
name: pyruvate
initial concentration: 0.527117851793548
is: C00022
constant: false

http://identifiers.org/biomodels.db/MODEL1303260006#_1d1b3e03_e55a_4fc1_8e4a_1db021538ced
constant: false
value: NaN
name: glycerate phosphates
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#_457eadf0_b73f_4404_9bc7_1043de81ae34
name: mM per second
type: SBMLUnitsDef

meta UGP1
has only substance units: false
initial amount: NaN
is: P32861
boundary condition: true
name: UGP1
initial concentration: 0.00155052854965178
is encoded by: S000001518
type: Species
is: SBO:0000252
in compartment: meta cell
constant: true

meta TPS1
has only substance units: false
is encoded by: S000000330
type: Species
initial concentration: 8.48120435592663E-4
initial amount: NaN
is: SBO:0000252
in compartment: meta cell
name: TPS1
boundary condition: true
is: Q00764
constant: true

http://identifiers.org/biomodels.db/MODEL1303260006#_9dcb0b5a_c90b_4f4c_b698_f6c6ee1b2d44
units: dimensionless
value: 10000.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#d5e69e6d_0138_4f91_bd37_b6c3236554d2
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

meta PEP
type: Species
name: phosphoenolpyruvate
is: SBO:0000247
constant: false
initial amount: NaN
is: CHEBI:18021
is: C00074
in compartment: meta cell
initial concentration: 0.152501353339511
boundary condition: false
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meta GLY
constant: true
has only substance units: false
type: Species
boundary condition: true
initial amount: NaN
is: SBO:0000247
is: CHEBI:17754
name: glycerol
is: C00116
initial concentration: 0.15
in compartment: meta cell

meta G6P
is: CHEBI:17665
has only substance units: false
initial amount: NaN
in compartment: meta cell
is: C00668
boundary condition: false
constant: false
initial concentration: 0.193120800911304
is: SBO:0000247
name: glucose 6-phosphate
type: Species

meta P3G
is: C00197
in compartment: meta cell
constant: false
initial amount: NaN
name: 3-phosphoglycerate
has only substance units: false
boundary condition: false
type: Species
initial concentration: 0.117456252783611
is: SBO:0000247
is: CHEBI:17794

http://identifiers.org/biomodels.db/MODEL1303260006#aa4150e0_d347_4c8f_aaeb_6901800c54d7
stoichiometry: 1.0
species: meta BPG
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meta PDC6
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constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0016352160527653
initial amount: NaN
in compartment: meta cell
name: PDC6
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_95a5bad3_e0f1_4ee6_8908_aab0c388ed18
value: 0.3
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#ae18eb4c_3245_42e8_b22f_e52548657c55
stoichiometry: 1.0
species: meta ADP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_30ea3807_61de_44c0_9e22_92f3e918a47f
stoichiometry: 1.0
species: meta GLC
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_99a1c0ba_0858_4210_a113_4c3ca0636724
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_940f2133_1d9a_4ca1_95fa_6145cba07fee
value: 0.111
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#dec0ad83_f0c3_4fca_ae81_55feb07705e1
value: 0.11
type: LocalParameter

meta PDC5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00308868608169189
initial amount: NaN
in compartment: meta cell
name: PDC5
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_61f9df45_7a39_42a8_81cf_d26d733645d3
stoichiometry: 1.0
species: meta P3G
type: SpeciesReference

meta HXK GLK1
is version of: http://identifiers.org/ec-code/2.7.1.1
is: SBO:0000176
is version of: GO:0004396
reversible: true
is: R02848
name: hexokinase [GLK1]
type: Reaction
fast: false
modifier: MODEL1303260006#

http://identifiers.org/biomodels.db/MODEL1303260006#bbbdeb1f_3cdc_47a4_9cfc_6ba07e486a0e
value: 0.195
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_395717d2_d005_4de0_8f94_c2aafdd58489
units: dimensionless
value: 6.7
type: LocalParameter

meta TPI1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.073589454911377
initial amount: NaN
in compartment: meta cell
name: TPI1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_115b933c_baf6_43a2_a367_8a6987f7ce19
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#cb3d7f7d_c2c7_4e29_b006_2aed9dedbe3f
stoichiometry: 3.0
species: meta NADH
type: SpeciesReference

meta PGM1
boundary condition: true
initial amount: NaN
in compartment: meta cell
is: SBO:0000252
is: P33401
type: Species
has only substance units: false
name: PGM1
constant: true
initial concentration: 8.15573865768647E-4
is encoded by: S000001610

http://identifiers.org/biomodels.db/MODEL1303260006#_9446cd26_b986_4983_bc4d_441695bfc2b2
value: 2.0
type: LocalParameter

W3 CDTF: Sun Nov 09 00:00:00 GMT 2008

meta ADH1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0409771277320022
initial amount: NaN
in compartment: meta cell
name: ADH1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_4da2157f_4528_487c_b898_ad003b48d7c2
value: 1.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_74a68be7_4146_4f6b_841b_9988878ad81c
value: 0.06
type: LocalParameter

meta T6P
is: CHEBI:18283
name: trehalose 6-phosphate
initial amount: NaN
type: Species
has only substance units: false
initial concentration: 0.02
is: SBO:0000247
in compartment: meta cell
boundary condition: false
constant: false

meta F26bP
has only substance units: false
is: C00665
in compartment: meta cell
name: fructose 2,6-bisphosphate
is: SBO:0000247
initial amount: NaN
is: CHEBI:28602
constant: true
type: Species
boundary condition: true
initial concentration: 0.003

http://identifiers.org/biomodels.db/MODEL1303260006#b079532b_82bb_4cc8_bdf5_a86339d0f840
constant: false
units: dimensionless
value: NaN
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#_0d65f19c_41a9_40bb_83ff_1fa59bc8333f
units: dimensionless
value: 800.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_896c065f_0b0c_414c_ae7d_1ff09b8567aa
stoichiometry: 1.0
species: meta NADH
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_9e78a261_b715_47e2_a1fb_970652832a09
value: 0.05
type: LocalParameter

meta PGM2
initial amount: NaN
is: SBO:0000252
boundary condition: true
constant: true
type: Species
name: PGM2
is encoded by: S000004711
initial concentration: 3.1467219294138E-4
is: P37012
has only substance units: false
in compartment: meta cell

http://identifiers.org/biomodels.db/MODEL1303260006#bd93a89a_fd4b_4023_a790_68ca2d615aaa
value: 0.613666666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#f4aa5cba_fe65_4e69_9ae1_88ecaf9003b4
exponent: 1.0
scale: 0
multipler: 1.0
kind: LITRE
type: SBMLUnit

http://identifiers.org/biomodels.db/MODEL1303260006#_15f202f8_666d_4325_95ec_e0191fe1e180
constant: true
value: 6.02
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#cf214ab3_ef82_4af9_b424_5fa0e474f9c2
value: 1.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_912f9d35_bde9_45a8_a8ec_0a1ab9146d73
value: 0.0098
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_47989b57_80dc_4520_b468_3f55d98d6c9a
value: 0.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_5de99da9_615f_437d_8ac0_19814166be4c
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

meta GPM1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.182500074724267
initial amount: NaN
in compartment: meta cell
name: GPM1
type: Species

meta HXK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0041951864287446
initial amount: NaN
in compartment: meta cell
name: HXK1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#c3de736a_0d50_4e78_8504_ac13cb11ad52
value: 1.11
type: LocalParameter

meta PDC1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.266952694557084
initial amount: NaN
in compartment: meta cell
name: PDC1
type: Species

meta GPD2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.98351416606057E-4
initial amount: NaN
in compartment: meta cell
name: GPD2
type: Species

meta GLK1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0112717406104807
initial amount: NaN
in compartment: meta cell
name: GLK1
type: Species

meta NADH
in compartment: meta cell
is: SBO:0000247
name: NADH
has only substance units: false
type: Species
initial concentration: 0.0867096979846952
constant: false
initial amount: NaN
is: C00004
is: CHEBI:16908
boundary condition: true

http://identifiers.org/biomodels.db/MODEL1303260006#_621b8781_80bd_4de7_a4c0_d07c0478079b
units: dimensionless
value: 0.397
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#ca801fdf_1b49_4c76_8185_1c65273b40f0
value: 0.53
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_7e965f92_6988_40b5_bba7_29e615beb1de
value: 0.0995
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#e8b4d563_3e50_48ba_9fa1_f2dd5bd5c0e6
value: 10.2
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_6e264a41_8072_4201_b776_7f059aa6de8b
value: 6.82E-4
type: LocalParameter

meta G3P
boundary condition: false
in compartment: meta cell
name: glycerol 3-phosphate
is: CHEBI:15978
is: SBO:0000247
type: Species
is: C00093
constant: false
has only substance units: false
initial amount: NaN
initial concentration: 0.068500732297821

meta EtOH
is: CHEBI:16236
name: ethanol
in compartment: meta cell
is: C00469
boundary condition: true
is: SBO:0000247
initial concentration: 55.472577854384
has only substance units: false
initial amount: NaN
type: Species
constant: true

meta HXK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0153328384926289
initial amount: NaN
in compartment: meta cell
name: HXK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#a83ba25f_eb07_40d3_a146_8264a9f6d11a
value: 0.883333333333333
type: LocalParameter

meta GPD1
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00170877794272468
initial amount: NaN
in compartment: meta cell
name: GPD1
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_22d7dac5_a649_4cf6_91b3_57ff74a02528
stoichiometry: 1.0
species: meta G6P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_9adcf04e_43b6_4f22_bd68_262afb0841a0
stoichiometry: 1.0
species: meta ATP
type: SpeciesReference

meta cell
is: GO:0005829
constant: true
size: 1.0
spatial dimensions: 3.0
name: cell
type: Compartment

http://identifiers.org/biomodels.db/MODEL1303260006#d9bbae23_d833_43a6_9f19_ea0a027e5c91
constant: true
value: 1.39784619487425
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#_0f547816_8dfe_4f74_985c_8c97aa742913
value: 43.0833333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_309fedb1_a9e4_490d_a752_fa75498e9af4
units: dimensionless
value: 0.045
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#bb7b6945_1ad6_4c56_a5d5_9f9b458407da
value: 0.108333333333333
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_8287ceac_2a5f_42ba_ad7f_a886ea9437b1
units: dimensionless
value: 1.9
type: LocalParameter

meta ADH5
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00106249605621922
initial amount: NaN
in compartment: meta cell
name: ADH5
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#_560f88bf_945b_4902_afd6_c0887cfa209b
units: dimensionless
value: 5.12
type: LocalParameter

meta ADH
name: alcohol dehydrogenase
is: SBO:0000176
is version of: http://identifiers.org/ec-code/1.1.1.1
type: Reaction
modifier: MODEL1303260006#
fast: false
reversible: true
is version of: GO:0004022
is: R00754

meta TRH
type: Species
is: C01083
initial amount: NaN
is: SBO:0000247
boundary condition: true
in compartment: meta cell
initial concentration: 0.00384697134241316
is: CHEBI:16551
has only substance units: false
constant: true
name: trehalose

http://identifiers.org/biomodels.db/MODEL1303260006#_200e6693_254b_4815_984c_b14c048809b8
value: 0.023
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_9b2799f1_9125_401e_ab94_bfb79319aff5
units: dimensionless
value: 0.91
type: LocalParameter

meta PYK2
is: SBO:0000252
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.00151748381804475
initial amount: NaN
in compartment: meta cell
name: PYK2
type: Species

http://identifiers.org/biomodels.db/MODEL1303260006#ecf84178_1cb4_44ad_857f_c4e9012ed143
value: 63.1
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_843a67e5_af21_4864_9856_c6d09d709e36
name: per mmol
type: SBMLUnitsDef

meta BPG
is: SBO:0000247
type: Species
boundary condition: false
is: CHEBI:16001
is: C00236
has only substance units: false
in compartment: meta cell
constant: false
initial concentration: 7.36873499865602E-4
initial amount: NaN
name: 1,3-bisphosphoglycerate

meta extracellular
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: extracellular
type: Compartment

meta ENO
is: R00658
is: SBO:0000176
modifier: MODEL1303260006#
type: Reaction
reversible: true
is version of: http://identifiers.org/ec-code/4.2.1.11
is version of: GO:0004634
fast: false
name: enolase

http://identifiers.org/biomodels.db/MODEL1303260006#_0cd9f343_0d6a_49db_8b3a_d4a159cb0b10
units: dimensionless
value: 14492.7536231884
type: LocalParameter

meta succinate branch
is: SBO:0000176
type: Reaction
modifier: MODEL1303260006#
fast: false
name: succinate branch
is version of: GO:0006105
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260006#_0c1b9fe9_962a_40b2_a0e9_f82e5f86eaf3
value: 7500.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_0c47c758_454d_4f8e_8983_a5d35383389c
stoichiometry: 1.0
species: meta G1P
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#_73463f74_e179_4c71_b354_bc566318d968
value: 1.57816666666667
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#d58e8573_6d2e_4663_a99d_f9502b77e9a3
value: 0.865
type: LocalParameter

meta PYK
fast: false
is: SBO:0000176
reversible: true
modifier: MODEL1303260006#
name: pyruvate kinase
is: R00200
type: Reaction
is version of: http://identifiers.org/ec-code/2.7.1.40
is version of: GO:0004743

http://identifiers.org/biomodels.db/MODEL1303260006#_4bfaaecf_c51a_4246_9bd5_a80adbb6599e
value: 0.069
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#c6c1a5e5_4d54_4a35_8448_f6f06f5f71ae
units: dimensionless
value: 0.66
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_01bd3f58_6662_40c0_8b67_3ad073c31173
constant: true
units: litre
value: 2.0E-14
name: volume
type: Parameter

http://identifiers.org/biomodels.db/MODEL1303260006#_8a488735_400a_4a8e_8ea0_25facdd96558
value: 0.0106
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_7b6594f3_cf0c_44fd_82fe_8c9e247cf302
value: 30.0
type: LocalParameter

http://identifiers.org/biomodels.db/MODEL1303260006#_5f0f9355_88c3_4d04_b89e_09a5d11e1810
stoichiometry: 1.0
species: meta PEP
type: SpeciesReference

http://identifiers.org/biomodels.db/MODEL1303260006#a7a0af63_45b2_4c2f_a010_edd5acd4e7e4
value: 90.0
type: LocalParameter

meta PDC
type: Reaction
is version of: GO:0004737
is: R00636
reversible: false
modifier: MODEL1303260006#
is version of: http://identifiers.org/ec-code/4.1.1.1
is: SBO:0000176
fast: false
name: pyruvate decarboxylase

http://identifiers.org/biomodels.db/MODEL1303260006#_7cbc5489_a69c_432d_b4c3_7d576974b9db
units: dimensionless
value: 0.19
type: LocalParameter

meta TPP
name: T6P phosphatase
type: Reaction
modifier: MODEL1303260006#
is version of: http://identifiers.org/ec-code/3.1.3.12
is: SBO:0000176
fast: false
reversible: false

http://identifiers.org/biomodels.db/MODEL1303260006#_19887bfb_deca_42d3_a303_4b47287e5905
name: per mM per second
type: SBMLUnitsDef

http://identifiers.org/biomodels.db/MODEL1303260006#_22d03be5_e6d4_4ba2_ba92_083f08fc3a61
value: 0.04
type: LocalParameter

W3 CDTF: Wed Nov 14 14:34:55 GMT 2012

orgname: University of Manchester

given: Kieran
family: Smallbone