297836
value: 0.0
type: LocalParameter

301408
value: 0.0
type: LocalParameter

299570
value: -0.023758
type: LocalParameter

292181
value: -999999.0
type: LocalParameter

287125
kinetic law: 345304
product: 345292
reactant: 345280
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_Isopropylmalate_transport__diffusion
type: Reaction

359409
stoichiometry: 1.0
species: 284787
type: SpeciesReference

351053
stoichiometry: 1.0
species: 284732
type: SpeciesReference

348987
stoichiometry: 1.0
species: 283497
type: SpeciesReference

297246
value: 0.0
type: LocalParameter

292255
value: 999999.0
type: LocalParameter

301592
value: 999999.0
type: LocalParameter

285562
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octanoate__n_C80__C8H15O2
type: Species

301407
value: 0.047411
type: LocalParameter

292180
value: 0.0
type: LocalParameter

299571
value: 0.0
type: LocalParameter

407274
stoichiometry: 1.0
species: 284805
type: SpeciesReference

440512
stoichiometry: 1.0
species: 286450
type: SpeciesReference

362820
stoichiometry: 1.0
species: 284876
type: SpeciesReference

293546
value: 0.0
type: LocalParameter

302120
value: 0.0
type: LocalParameter

388945
stoichiometry: 0.655
species: 284846
type: SpeciesReference

297247
value: 0.0
type: LocalParameter

284732
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_GTP_C10H12N5O14P3
type: Species

378940
stoichiometry: 1.0
species: 285925
type: SpeciesReference

289960
name: R_NAD_nucleosidase__mitochondrial
product: 414435
product: 414423
reactant: 414411
reactant: 414399
reversible: false
product: 414447
fast: false
kinetic law: 414460
type: Reaction
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 3.2.2.5

293309
value: 0.0
type: LocalParameter

299572
value: 999999.0
type: LocalParameter

400131
stoichiometry: 1.0
species: 284808
type: SpeciesReference

297834
value: 0.0
type: LocalParameter

379772
stoichiometry: 1.0
species: 286405
type: SpeciesReference

289962
product: 414509
name: R_NADP_phosphatase
product: 414497
kinetic law: 414521
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS:
fast: false
reactant: 414472
reactant: 414485
reversible: false
type: Reaction

302278
value: -999999.0
type: LocalParameter

284945
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hexadecanal_C16H32O
type: Species

390396
stoichiometry: 1.0
species: 283836
type: SpeciesReference

295075
value: 0.0
type: LocalParameter

292253
value: 0.0
type: LocalParameter

396847
stoichiometry: 1.0
species: 284766
type: SpeciesReference

289271
fast: false
reactant: 392014
product: 392050
reactant: 392002
type: Reaction
product: 392038
kinetic law: 392062
product: 392026
name: R_glucose_6_phosphate_dehydrogenase__endoplasmic_reticulum
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS:
reversible: false

400832
stoichiometry: 1.0
species: 285399
type: SpeciesReference

427610
stoichiometry: 1.0
species: 285487
type: SpeciesReference

436202
stoichiometry: 1.0
species: 286246
type: SpeciesReference

363000
stoichiometry: 1.0
species: 284013
type: SpeciesReference

439737
stoichiometry: 1.0
species: 284624
type: SpeciesReference

297245
value: 999999.0
type: LocalParameter

302279
value: 999999.0
type: LocalParameter

290530
kinetic law: 432622
product: 432610
reactant: 432597
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_sorbitol_transport_via_passive_diffusion
type: Reaction

293544
value: 0.0
type: LocalParameter

292879
value: 0.0
type: LocalParameter

292252
value: 0.0
type: LocalParameter

285787
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Porphobilinogen_C10H13N2O4
type: Species

303777
value: 0.0
type: LocalParameter

397161
stoichiometry: 1.0
species: 286516
type: SpeciesReference

362940
stoichiometry: 1.0
species: 284802
type: SpeciesReference

349362
stoichiometry: 1.0
species: 285778
type: SpeciesReference

297832
value: 0.01612
type: LocalParameter

289385
reactant: 395747
product: 395783
product: 395795
fast: false
reversible: false
reactant: 395759
type: Reaction
notes: GENE_ASSOCIATION: YGL245W PROTEIN_ASSOCIATION: Mse2 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.17
name: R_Glutamyl_tRNA_synthetase
reactant: 395771
kinetic law: 395819
product: 395807

289964
type: Reaction
name: R_NADP_phosphatase
product: 414557
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS:
reactant: 414545
product: 414569
reactant: 414533
reversible: false
kinetic law: 414581

426799
stoichiometry: 1.0
species: 283713
type: SpeciesReference

384240
stoichiometry: 1.0
species: 285433
type: SpeciesReference

301404
value: 0.0
type: LocalParameter

299574
value: 0.0
type: LocalParameter

299575
value: 0.0
type: LocalParameter

419009
stoichiometry: 1.0
species: 283137
type: SpeciesReference

293771
value: 0.067908
type: LocalParameter

301596
value: 0.0
type: LocalParameter

285784
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M__R__Pantothenate_C9H16NO5
type: Species

388272
stoichiometry: 1.0
species: 283521
type: SpeciesReference

394190
stoichiometry: 1.0
species: 284085
type: SpeciesReference

292259
value: 0.221001
type: LocalParameter

293549
value: 0.0
type: LocalParameter

430285
stoichiometry: 1.0
species: 285961
type: SpeciesReference

395579
stoichiometry: 1.0
species: 284595
type: SpeciesReference

344275
stoichiometry: 1.0
species: 284787
type: SpeciesReference

301403
value: 999999.0
type: LocalParameter

289273
kinetic law: 392099
product: 392086
reactant: 392074
notes: GENE_ASSOCIATION: YBR196C PROTEIN_ASSOCIATION: Pgi1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.3.1.9
fast: false
reversible: true
name: R_Glucose_6_phosphate_isomerase
type: Reaction

393259
stoichiometry: 1.0
species: 283689
type: SpeciesReference

439181
stoichiometry: 1.0
species: 286372
type: SpeciesReference

284942
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

292877
value: 999999.0
type: LocalParameter

411352
stoichiometry: 1.0
species: 283611
type: SpeciesReference

290532
kinetic law: 432658
product: 432646
reactant: 432634
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_sorbitol_transport_via_passive_diffusion
type: Reaction

398203
stoichiometry: 1.0
species: 284787
type: SpeciesReference

303775
value: 0.0
type: LocalParameter

292982
value: 0.0
type: LocalParameter

297830
value: 999999.0
type: LocalParameter

396507
stoichiometry: 1.0
species: 285460
type: SpeciesReference

442872
stoichiometry: 0.655
species: 284837
type: SpeciesReference

303779
value: -999999.0
type: LocalParameter

421634
stoichiometry: 1.0
species: 286000
type: SpeciesReference

289966
kinetic law: 414617
product: 414605
reactant: 414593
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_NADP_transporter
type: Reaction

415176
stoichiometry: 1.0
species: 284787
type: SpeciesReference

435743
stoichiometry: 1.0
species: 285487
type: SpeciesReference

289387
product: 395891
product: 395867
kinetic law: 395903
reactant: 395843
product: 395879
fast: false
type: Reaction
name: R_glutamyl_tRNA_synthetase__mitochondrial
notes: GENE_ASSOCIATION: YOL033W PROTEIN_ASSOCIATION: Mse1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.17
reversible: false
reactant: 395831
reactant: 395855

364972
stoichiometry: 1.0
species: 285664
type: SpeciesReference

283578
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__Acetoin_C4H8O2
type: Species

404192
stoichiometry: 1.0
species: 285409
type: SpeciesReference

362084
stoichiometry: 1.0
species: 283908
type: SpeciesReference

292874
value: -0.115621
type: LocalParameter

287122
reactant: 345220
product: 345256
kinetic law: 345268
name: R_3__4_hydroxyphenyl_pyruvate_peroxisomal_transport_via_proton_symport
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
type: Reaction
product: 345244
fast: false
reactant: 345232
reversible: true

299577
value: -0.023758
type: LocalParameter

379097
stoichiometry: 1.0
species: 286960
type: SpeciesReference

417814
stoichiometry: 1.0
species: 284787
type: SpeciesReference

292257
value: 0.0
type: LocalParameter

365816
stoichiometry: 1.0
species: 283968
type: SpeciesReference

412598
stoichiometry: 0.01
species: 285348
type: SpeciesReference

443500
stoichiometry: 1.0E-6
species: 285396
type: SpeciesReference

297831
value: 0.0
type: LocalParameter

288202
reversible: false
notes: GENE_ASSOCIATION: ( YBR249C or YDR035W ) PROTEIN_ASSOCIATION: ( Aro4 ) or ( Aro3 ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.2.15
reactant: 368324
reactant: 368349
kinetic law: 368385
product: 368373
reactant: 368336
fast: false
product: 368361
name: R_3_deoxy_D_arabino_heptulosonate_7_phosphate_synthetase
type: Reaction

303778
value: 0.0
type: LocalParameter

410736
stoichiometry: 1.0
species: 284562
type: SpeciesReference

289275
kinetic law: 392135
product: 392123
reactant: 392111
notes: GENE_ASSOCIATION: YBR196C PROTEIN_ASSOCIATION: Pgi1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.3.1.9
fast: false
reversible: true
name: R_Glucose_6_phosphate_isomerase
type: Reaction

289389
reactant: 395915
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
reversible: true
fast: false
type: Reaction
product: 395939
name: R_glutamate_nuclear_transport_via_proton_symport
product: 395951
kinetic law: 395963
reactant: 395927

299578
value: 0.0
type: LocalParameter

301593
value: 0.0
type: LocalParameter

292875
value: -999999.0
type: LocalParameter

301400
value: 0.0
type: LocalParameter

295072
value: 999999.0
type: LocalParameter

418479
stoichiometry: 1.0
species: 285532
type: SpeciesReference

290534
name: R_serine_O_acetyltransferase__irreversible
reactant: 432670
reactant: 432682
fast: false
product: 432694
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 2.3.1.30
kinetic law: 432718
type: Reaction
reversible: false
product: 432706

368010
stoichiometry: 1.0
species: 284133
type: SpeciesReference

292980
value: 0.0
type: LocalParameter

293548
value: 0.0
type: LocalParameter

357822
stoichiometry: 1.0
species: 284787
type: SpeciesReference

297249
value: 0.0
type: LocalParameter

395350
stoichiometry: 1.0
species: 283641
type: SpeciesReference

302397
value: -999999.0
type: LocalParameter

290640
fast: false
product: 436276
name: R_Thioredoxin__nuclear__irreversible
notes: GENE_ASSOCIATION: ( ( YIL010W and YLR043C ) or ( YIL010W and YGR209C ) ) PROTEIN_ASSOCIATION: ( Dot5-n and Trx1 ) or ( Dot5-n and Trx2 ) SUBSYSTEM: S_Other PROTEIN_CLASS:
reversible: false
type: Reaction
reactant: 436251
reactant: 436263
product: 436288
kinetic law: 436300

283572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_O_Acetylcarnitine_C9H17NO4
type: Species

292872
value: 0.0
type: LocalParameter

366501
stoichiometry: 1.0
species: 284064
type: SpeciesReference

384132
stoichiometry: 8.0
species: 284778
type: SpeciesReference

292985
value: 999999.0
type: LocalParameter

401517
stoichiometry: 1.0
species: 285285
type: SpeciesReference

302272
value: 999999.0
type: LocalParameter

299579
value: 999999.0
type: LocalParameter

293303
value: 999999.0
type: LocalParameter

414764
stoichiometry: 1.0
species: 283719
type: SpeciesReference

348530
stoichiometry: 1.0
species: 283548
type: SpeciesReference

287278
product: 348097
reversible: false
reactant: 348085
name: R_acetyl_CoA_acyltransferase__tetracosanoyl_CoA___peroxisomal
kinetic law: 348121
product: 348109
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16
reactant: 348073
fast: false
type: Reaction

289381
notes: GENE_ASSOCIATION: YMR300C PROTEIN_ASSOCIATION: Ade4 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.14
name: R_glutamine_phosphoribosyldiphosphate_amidotransferase
reversible: false
product: 395615
type: Reaction
product: 395639
reactant: 395603
reactant: 395591
product: 395627
reactant: 395579
fast: false
kinetic law: 395651

415065
stoichiometry: 1.0
species: 283602
type: SpeciesReference

384770
stoichiometry: 8.0
species: 285418
type: SpeciesReference

302128
value: 0.0
type: LocalParameter

297941
value: 0.0
type: LocalParameter

372182
stoichiometry: 1.0
species: 285113
type: SpeciesReference

371663
stoichiometry: 1.0
species: 284787
type: SpeciesReference

374463
stoichiometry: 1.0
species: 283092
type: SpeciesReference

288364
kinetic law: 371869
name: R_dUTP_diphosphatase
reversible: false
reactant: 371820
fast: false
reactant: 371807
notes: GENE_ASSOCIATION: YBR252W PROTEIN_ASSOCIATION: Dut1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.6.1.23
type: Reaction
product: 371845
product: 371857
product: 371832

284526
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_D_Glucose_6_phosphate_C6H11O9P
type: Species

302398
value: 999999.0
type: LocalParameter

429473
stoichiometry: 1.0
species: 285940
type: SpeciesReference

400567
stoichiometry: 1.0
species: 283602
type: SpeciesReference

303884
value: 0.0
type: LocalParameter

439072
stoichiometry: 1.0
species: 283437
type: SpeciesReference

362192
stoichiometry: 1.0
species: 283905
type: SpeciesReference

300749
value: -0.011879
type: LocalParameter

376056
stoichiometry: 1.0
species: 284343
type: SpeciesReference

289277
kinetic law: 392173
product: 392160
reactant: 392147
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_glucose_6_phosphate_endoplasmic_reticular_transport_via_diffusion
type: Reaction

407347
stoichiometry: 1.0
species: 284787
type: SpeciesReference

357762
stoichiometry: 1.0
species: 284595
type: SpeciesReference

344384
stoichiometry: 1.0
species: 283701
type: SpeciesReference

288208
reactant: 368469
kinetic law: 368553
reactant: 368493
product: 368517
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 1.14.19.1
reversible: false
product: 368529
type: Reaction
name: R_Myristicoyl_CoA_desaturase__n_C140CoA___n_C141CoA_
fast: false
product: 368541
reactant: 368505
reactant: 368481

297942
value: 0.0
type: LocalParameter

302125
value: 999999.0
type: LocalParameter

288361
fast: false
product: 371771
kinetic law: 371795
product: 371783
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
type: Reaction
reversible: false
reactant: 371747
reactant: 371759
name: R_deoxyuridine_transport_in_via_proton_symport

292870
value: 0.0
type: LocalParameter

289670
type: Reaction
reactant: 404534
fast: false
name: R_inosine_transport_in_via_proton_symport
reversible: false
reactant: 404547
product: 404560
kinetic law: 404586
product: 404573
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:

290642
product: 436348
product: 436336
notes: GENE_ASSOCIATION: ( ( YLR109W and YLR043C ) or ( YLR109W and YGR209C ) ) PROTEIN_ASSOCIATION: ( Ahp1-p and Trx1 ) or ( Ahp1-p and Trx2 ) SUBSYSTEM: S_Other PROTEIN_CLASS:
reactant: 436312
reactant: 436324
reversible: true
type: Reaction
name: R_hydrogen_peroxide_reductase__thioredoxin___peroxisomal
kinetic law: 436361
fast: false

387852
stoichiometry: 3.0
species: 284013
type: SpeciesReference

289279
reversible: true
product: 392221
fast: false
notes: GENE_ASSOCIATION: YBR184W PROTEIN_ASSOCIATION: Mel1 SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 3.2.1.22
product: 392209
type: Reaction
reactant: 392197
name: R_1_alpha_D_Galactosyl_myo_inositol_galactohydrolase
kinetic law: 392233
reactant: 392185

302270
value: -0.056821
type: LocalParameter

292983
value: 0.0
type: LocalParameter

289383
notes: GENE_ASSOCIATION: YDL171C PROTEIN_ASSOCIATION: Glt1 SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 1.4.1.14
kinetic law: 395735
name: R_glutamate_synthase__NADH2_
reactant: 395663
type: Reaction
reversible: false
reactant: 395687
reactant: 395675
product: 395711
product: 395723
fast: false
reactant: 395699

383951
stoichiometry: 7.0
species: 284754
type: SpeciesReference

426196
stoichiometry: 1.0
species: 283830
type: SpeciesReference

395687
stoichiometry: 1.0
species: 284787
type: SpeciesReference

288205
type: Reaction
reactant: 368421
reactant: 368409
name: R_2_deoxy_D_arabino_heptulosonate_7_phosphate_synthetase__mitochondrial
product: 368433
notes: GENE_ASSOCIATION: YDR035W PROTEIN_ASSOCIATION: Aro3-m SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.2.15
fast: false
kinetic law: 368457
product: 368445
reactant: 368397
reversible: false

293301
value: -999999.0
type: LocalParameter

406632
stoichiometry: 0.02
species: 284831
type: SpeciesReference

411207
stoichiometry: 1.0
species: 283611
type: SpeciesReference

303886
value: 999999.0
type: LocalParameter

357979
stoichiometry: 1.0
species: 283716
type: SpeciesReference

283575
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_O_Acetyl_L_serine_C5H9NO4
type: Species

283422
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Arabinono_1_4_lactone_C5H8O5
type: Species

302396
value: 0.0
type: LocalParameter

302271
value: -999999.0
type: LocalParameter

356667
stoichiometry: 1.0
species: 284747
type: SpeciesReference

288509
kinetic law: 374668
product: 374655
reactant: 374643
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_Aminobenzoate_exchange
type: Reaction

302127
value: 0.0
type: LocalParameter

421524
stoichiometry: 1.0
species: 286129
type: SpeciesReference

294929
value: 999999.0
type: LocalParameter

303887
value: 0.0
type: LocalParameter

302062
value: 0.0
type: LocalParameter

302393
value: 0.0
type: LocalParameter

284523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucose_6_phosphate_C6H11O9P
type: Species

292989
value: 0.0
type: LocalParameter

384011
stoichiometry: 7.0
species: 284778
type: SpeciesReference

383382
stoichiometry: 1.0
species: 285565
type: SpeciesReference

443006
stoichiometry: 0.655
species: 284840
type: SpeciesReference

302123
value: 0.0
type: LocalParameter

297241
value: -0.079589
type: LocalParameter

381042
stoichiometry: 1.0
species: 285772
type: SpeciesReference

288506
kinetic law: 374631
product: 374619
reactant: 374607
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_Aminobutanoate_exchange
type: Reaction

400724
stoichiometry: 1.0
species: 284885
type: SpeciesReference

293307
value: 0.0
type: LocalParameter

295078
value: 0.0
type: LocalParameter

415803
stoichiometry: 1.0
species: 284133
type: SpeciesReference

302063
value: 999999.0
type: LocalParameter

404496
stoichiometry: 1.0
species: 284787
type: SpeciesReference

414908
stoichiometry: 1.0
species: 285796
type: SpeciesReference

403757
stoichiometry: 1.0
species: 285020
type: SpeciesReference

437911
stoichiometry: 1.0
species: 285751
type: SpeciesReference

298048
value: 0.0
type: LocalParameter

292250
value: 0.221001
type: LocalParameter

302394
value: 0.0
type: LocalParameter

297243
value: 0.0
type: LocalParameter

302124
value: 0.0
type: LocalParameter

363156
stoichiometry: 1.0
species: 284787
type: SpeciesReference

302277
value: 0.0
type: LocalParameter

303889
value: 0.0
type: LocalParameter

435140
stoichiometry: 1.0
species: 284493
type: SpeciesReference

356450
stoichiometry: 1.0
species: 283482
type: SpeciesReference

352802
stoichiometry: 1.0
species: 283644
type: SpeciesReference

297946
value: 0.0
type: LocalParameter

287128
kinetic law: 345340
product: 345328
reactant: 345316
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_Isopropylmalate_transport__diffusion__mitochondrial
type: Reaction

436991
stoichiometry: 1.0
species: 286204
type: SpeciesReference

292987
value: 0.0
type: LocalParameter

283425
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_2_Aminoadipate_6_semialdehyde_C6H11NO3
type: Species

442703
stoichiometry: 0.655
species: 284846
type: SpeciesReference

302391
value: 999999.0
type: LocalParameter

298047
value: 999999.0
type: LocalParameter

390287
stoichiometry: 1.0
species: 284787
type: SpeciesReference

302060
value: 0.0
type: LocalParameter

302274
value: 0.0
type: LocalParameter

302121
value: 0.0
type: LocalParameter

300746
value: 0.0
type: LocalParameter

375996
stoichiometry: 1.0
species: 286705
type: SpeciesReference

426244
stoichiometry: 2.0
species: 284787
type: SpeciesReference

297943
value: 999999.0
type: LocalParameter

296700
value: 0.0
type: LocalParameter

427149
stoichiometry: 0.01
species: 285682
type: SpeciesReference

400288
stoichiometry: 1.0
species: 284861
type: SpeciesReference

352994
stoichiometry: 3.0
species: 284757
type: SpeciesReference

362712
stoichiometry: 1.0
species: 284013
type: SpeciesReference

293305
value: 0.0
type: LocalParameter

298046
value: 0.0
type: LocalParameter

345316
stoichiometry: 1.0
species: 283125
type: SpeciesReference

284520
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_beta_D_glucose_6_phosphate_C6H11O9P
type: Species

367069
stoichiometry: 1.0
species: 284562
type: SpeciesReference

302061
value: 0.0
type: LocalParameter

284948
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indole_3_acetamide_C10H10N2O
type: Species

436639
stoichiometry: 1.0
species: 286183
type: SpeciesReference

351161
stoichiometry: 1.0
species: 283713
type: SpeciesReference

300747
value: 0.0
type: LocalParameter

302275
value: 0.0
type: LocalParameter

353236
stoichiometry: 1.0
species: 285949
type: SpeciesReference

360197
stoichiometry: 1.0
species: 284787
type: SpeciesReference

396738
stoichiometry: 1.0
species: 284669
type: SpeciesReference

352658
stoichiometry: 1.0
species: 285162
type: SpeciesReference

393839
stoichiometry: 1.0
species: 284583
type: SpeciesReference

379664
stoichiometry: 1.0
species: 286228
type: SpeciesReference

297944
value: 0.0
type: LocalParameter

298045
value: -0.009305
type: LocalParameter

297938
value: 0.0
type: LocalParameter

293849
value: 999999.0
type: LocalParameter

371505
stoichiometry: 1.0
species: 283602
type: SpeciesReference

285026
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3__Imidazol_4_yl__2_oxopropyl_phosphate_C6H7N2O5P
type: Species

440407
stoichiometry: 1.0
species: 286450
type: SpeciesReference

298055
value: 0.0
type: LocalParameter

288503
kinetic law: 374595
product: 374583
reactant: 374571
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_3mop_exchange
type: Reaction

289666
type: Reaction
reactant: 404408
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.1.73
product: 404421
name: R_insosine_kinase
reversible: false
fast: false
reactant: 404396
product: 404445
product: 404433
kinetic law: 404457

413685
stoichiometry: 1.0
species: 285427
type: SpeciesReference

371444
stoichiometry: 1.0
species: 283371
type: SpeciesReference

302055
value: 0.0
type: LocalParameter

394082
stoichiometry: 1.0
species: 285360
type: SpeciesReference

405568
stoichiometry: 1.0
species: 284757
type: SpeciesReference

406054
stoichiometry: 1.0
species: 284757
type: SpeciesReference

283947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Chitosan_C6H11NO4
type: Species

283416
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_acyl_carrier_protein_C11H21N2O7PRS
type: Species

374318
stoichiometry: 1.0
species: 283041
type: SpeciesReference

389187
stoichiometry: 0.01
species: 284439
type: SpeciesReference

353925
stoichiometry: 1.0
species: 285421
type: SpeciesReference

378397
stoichiometry: 1.0
species: 285532
type: SpeciesReference

434099
stoichiometry: 1.0
species: 286078
type: SpeciesReference

396957
stoichiometry: 1.0
species: 283713
type: SpeciesReference

298056
value: 0.0
type: LocalParameter

359953
stoichiometry: 1.0
species: 284766
type: SpeciesReference

384552
stoichiometry: 8.0
species: 285406
type: SpeciesReference

289512
kinetic law: 399711
type: Reaction
reactant: 399638
name: R_homocitrate_synthase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 4.1.3.21
reactant: 399662
reversible: false
fast: false
product: 399674
product: 399699
product: 399686
reactant: 399650

378103
stoichiometry: 1.0
species: 285366
type: SpeciesReference

300751
value: 999999.0
type: LocalParameter

290648
reactant: 436518
name: R_thiamin_phosphatase
reversible: false
type: Reaction
product: 436530
kinetic law: 436555
reactant: 436506
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS:
fast: false
product: 436543

391062
stoichiometry: 1.0
species: 284793
type: SpeciesReference

293610
value: 0.0
type: LocalParameter

302054
value: 0.0
type: LocalParameter

351721
stoichiometry: 1.0
species: 284130
type: SpeciesReference

363592
stoichiometry: 1.0
species: 283935
type: SpeciesReference

373895
stoichiometry: 1.0
species: 284352
type: SpeciesReference

392704
stoichiometry: 1.0
species: 282889
type: SpeciesReference

287281
kinetic law: 348157
product: 348145
reactant: 348133
notes: GENE_ASSOCIATION: ( YLR044C or YGR087C or YLR134W ) PROTEIN_ASSOCIATION: ( Pdc1 ) or ( Pdc6 ) or ( Pdc5 ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS:
fast: false
reversible: false
name: R_Acetaldehyde_condensation
type: Reaction

283833
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_ATP_C10H12N5O13P3
type: Species

425676
stoichiometry: 1.0
species: 285793
type: SpeciesReference

356884
stoichiometry: 1.0
species: 283755
type: SpeciesReference

299420
value: 0.0
type: LocalParameter

410627
stoichiometry: 1.0
species: 284052
type: SpeciesReference

348313
stoichiometry: 1.0
species: 285751
type: SpeciesReference

298053
value: 999999.0
type: LocalParameter

297936
value: 999999.0
type: LocalParameter

390929
stoichiometry: 1.0
species: 284787
type: SpeciesReference

435477
stoichiometry: 1.0
species: 283470
type: SpeciesReference

289668
type: Reaction
fast: false
reversible: false
name: R_inositol_transport_in_via_proton_symport
product: 404496
reactant: 404483
reactant: 404470
notes: GENE_ASSOCIATION: ( YDR497C or YOL103W ) PROTEIN_ASSOCIATION: ( Itr1 ) or ( Itr2 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 404508
kinetic law: 404521

380558
stoichiometry: 1.0
species: 285772
type: SpeciesReference

293992
value: 999999.0
type: LocalParameter

368167
stoichiometry: 1.0
species: 285454
type: SpeciesReference

302053
value: 0.0
type: LocalParameter

300755
value: 0.0
type: LocalParameter

430975
stoichiometry: 1.0
species: 283611
type: SpeciesReference

418077
stoichiometry: 1.0
species: 284618
type: SpeciesReference

429257
stoichiometry: 1.0
species: 285928
type: SpeciesReference

299421
value: 0.0
type: LocalParameter

297935
value: 0.0
type: LocalParameter

407128
stoichiometry: 1.0
species: 285146
type: SpeciesReference

415285
stoichiometry: 1.0
species: 284175
type: SpeciesReference

288500
kinetic law: 374559
product: 374547
reactant: 374535
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_Methylbutanal_exchange
type: Reaction

285023
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Isoleucyl_tRNA_Ile__C6H12NOR
type: Species

289514
type: Reaction
product: 399784
reversible: false
product: 399760
reactant: 399723
reactant: 399735
notes: GENE_ASSOCIATION: ( YDL131W or YDL182W ) PROTEIN_ASSOCIATION: ( Lys21-n ) or ( Lys20-n ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 4.1.3.21
product: 399772
reactant: 399748
fast: false
kinetic law: 399796
name: R_homocitrate_synthase

369924
stoichiometry: 1.0
species: 284229
type: SpeciesReference

383733
stoichiometry: 6.0
species: 284025
type: SpeciesReference

421307
stoichiometry: 1.0
species: 285685
type: SpeciesReference

288358
name: R_deoxyuridine_phosphorylase
kinetic law: 371735
product: 371711
type: Reaction
notes: GENE_ASSOCIATION: YLR209C PROTEIN_ASSOCIATION: Pnp1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS:
reversible: true
reactant: 371699
fast: false
product: 371723
reactant: 371687

294922
value: 0.0
type: LocalParameter

293769
value: 0.0
type: LocalParameter

284307
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Deoxyuridine_C9H12N2O5
type: Species

283356
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4__1_D_Ribitylamino__5_aminouracil_C9H16N4O6
type: Species

300754
value: 0.0
type: LocalParameter

283203
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M__S__3_Methyl_2_oxopentanoate_C6H9O3
type: Species

283944
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Chitin__monomer__C8H13NO5
type: Species

293846
value: -999999.0
type: LocalParameter

364306
stoichiometry: 1.0
species: 283968
type: SpeciesReference

383164
stoichiometry: 1.0
species: 285796
type: SpeciesReference

293312
value: 999999.0
type: LocalParameter

298342
value: 0.0
type: LocalParameter

355085
stoichiometry: 1.0
species: 284766
type: SpeciesReference

403974
stoichiometry: 1.0
species: 285017
type: SpeciesReference

298051
value: -0.008909
type: LocalParameter

302281
value: 0.0
type: LocalParameter

293998
value: 0.0
type: LocalParameter

287284
kinetic law: 348193
product: 348181
reactant: 348169
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_acetaldehyde_reversible_transport
type: Reaction

384468
stoichiometry: 6.0
species: 284808
type: SpeciesReference

293845
value: 0.0
type: LocalParameter

363229
stoichiometry: 1.0
species: 284802
type: SpeciesReference

283206
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__S__3_Methyl_2_oxopentanoate_C6H9O3
type: Species

291498
value: 999999.0
type: LocalParameter

431811
stoichiometry: 1.0
species: 284757
type: SpeciesReference

284304
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_dUMP_C9H11N2O8P
type: Species

283830
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_ATP_C10H12N5O13P3
type: Species

303880
value: 0.0
type: LocalParameter

345653
stoichiometry: 1.0
species: 284001
type: SpeciesReference

443223
stoichiometry: 1.0E-6
species: 283944
type: SpeciesReference

363374
stoichiometry: 1.0
species: 285436
type: SpeciesReference

353453
stoichiometry: 1.0
species: 284787
type: SpeciesReference

436312
stoichiometry: 1.0
species: 284754
type: SpeciesReference

289516
type: Reaction
name: R_HCO3_equilibration_reaction
kinetic law: 399862
product: 399849
product: 399835
reversible: true
reactant: 399809
reactant: 399822
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Other PROTEIN_CLASS: 4.2.1.1

298052
value: 0.0
type: LocalParameter

285029
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_IMP_C10H11N4O8P
type: Species

292033
value: -0.266906
type: LocalParameter

288650
kinetic law: 376370
product: 376358
reactant: 376345
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_FMN_exchange
type: Reaction

283419
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_acyl_carrier_protein_C11H21N2O7PRS
type: Species

290644
product: 436421
product: 436397
kinetic law: 436433
reactant: 436373
notes: GENE_ASSOCIATION: YBR092C PROTEIN_ASSOCIATION: Pho3-e SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 3.1.3.2
fast: false
type: Reaction
reversible: false
product: 436409
reactant: 436385
name: R_thiamin_diphosphatase__extracellular

344714
stoichiometry: 1.0
species: 283050
type: SpeciesReference

302058
value: 0.0
type: LocalParameter

350340
stoichiometry: 1.0
species: 283500
type: SpeciesReference

283350
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_4__Phosphopantothenate_C9H15NO8P
type: Species

298344
value: 0.0
type: LocalParameter

289660
kinetic law: 404288
product: 404276
reactant: 404264
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_Tryptophol_transport__extracellular
type: Reaction

419457
stoichiometry: 1.0
species: 285604
type: SpeciesReference

434511
stoichiometry: 1.0
species: 286090
type: SpeciesReference

300750
value: 0.0
type: LocalParameter

289664
notes: GENE_ASSOCIATION: ( YLR134W or YLR044C or YGR087C or YDR380W ) PROTEIN_ASSOCIATION: ( Pdc5 ) or ( Pdc1 ) or ( Pdc6 ) or ( Aro10 ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.1.74
reactant: 404348
name: R_Indole_3_pyruvate_decarboxylase
type: Reaction
reactant: 404336
product: 404372
fast: false
reversible: true
kinetic law: 404384
product: 404360

293310
value: 0.0
type: LocalParameter

288355
reactant: 371626
product: 371650
reversible: false
product: 371638
fast: false
type: Reaction
kinetic law: 371675
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS:
reactant: 371614
product: 371663
name: R_deoxyuridine_kinase__ATPDeoxyuridine_

410853
stoichiometry: 1.0
species: 283695
type: SpeciesReference

401097
stoichiometry: 1.0
species: 285796
type: SpeciesReference

348265
stoichiometry: 1.0
species: 284817
type: SpeciesReference

404276
stoichiometry: 1.0
species: 285044
type: SpeciesReference

303882
value: 0.0
type: LocalParameter

302057
value: 999999.0
type: LocalParameter

283353
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N___R__4_Phosphopantothenoyl__L_cysteine_C12H20N2O9PS
type: Species

294925
value: -0.013364
type: LocalParameter

433081
stoichiometry: 1.0
species: 284757
type: SpeciesReference

298341
value: 0.0
type: LocalParameter

412150
stoichiometry: 0.01
species: 282893
type: SpeciesReference

298050
value: 0.0
type: LocalParameter

297939
value: 0.0
type: LocalParameter

289518
reactant: 399888
kinetic law: 399925
reversible: true
name: R_HCO3_equilibration_reaction
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Other PROTEIN_CLASS:
product: 399913
type: Reaction
reactant: 399875
product: 399901

287287
kinetic law: 348229
product: 348217
reactant: 348205
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_acetaldehyde_mitochondrial_diffusion
type: Reaction

292031
value: 0.0
type: LocalParameter

293995
value: 0.0
type: LocalParameter

293842
value: 0.0
type: LocalParameter

289662
kinetic law: 404324
product: 404312
reactant: 404300
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_Tryptophol_transport__mitochondrial_
type: Reaction

284517
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_sn_Glycero_3_phospho_1_inositol_C9H18O11P
type: Species

303883
value: -0.023758
type: LocalParameter

290646
name: R_thymidine_transport_in_via_proton_symport
product: 436482
reactant: 436445
fast: false
type: Reaction
product: 436470
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
kinetic law: 436494
reactant: 436457
reversible: false

294926
value: -999999.0
type: LocalParameter

350799
stoichiometry: 1.0
species: 283584
type: SpeciesReference

290536
kinetic law: 432766
product: 432754
product: 432742
reactant: 432730
notes: GENE_ASSOCIATION: ( YCL064C or YIL168W ) PROTEIN_ASSOCIATION: ( Cha1 ) or ( Sdl1 ) SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 4.3.1.17
fast: false
reversible: false
name: R_L_serine_deaminase
type: Reaction

293764
value: 0.0
type: LocalParameter

298347
value: 0.0
type: LocalParameter

303771
value: 0.0
type: LocalParameter

292189
value: 0.0
type: LocalParameter

285781
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__Pantothenate_C9H16NO5
type: Species

292036
value: -999999.0
type: LocalParameter

378722
stoichiometry: 1.0
species: 285721
type: SpeciesReference

299427
value: 0.0
type: LocalParameter

391641
stoichiometry: 1.0
species: 284615
type: SpeciesReference

293203
value: 999999.0
type: LocalParameter

357065
stoichiometry: 1.0
species: 283773
type: SpeciesReference

288656
kinetic law: 376444
product: 376431
reactant: 376419
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Fructose_exchange
type: Reaction

407492
stoichiometry: 1.0
species: 284466
type: SpeciesReference

293619
value: 0.0
type: LocalParameter

291082
value: 0.0
type: LocalParameter

356389
stoichiometry: 1.0
species: 284787
type: SpeciesReference

419348
stoichiometry: 1.0
species: 285592
type: SpeciesReference

284951
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_isoamyl_acetate_C7H14O2
type: Species

303772
value: -999999.0
type: LocalParameter

284729
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_Reduced_glutathione_C10H16N3O6S
type: Species

284301
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_dUMP_C9H11N2O8P
type: Species

293763
value: 0.0
type: LocalParameter

385935
stoichiometry: 2.0
species: 285439
type: SpeciesReference

289968
reversible: false
kinetic law: 414715
type: Reaction
product: 414678
reactant: 414653
product: 414690
product: 414702
reactant: 414629
name: R_NAD_synthase__nh3_
product: 414665
fast: false
reactant: 414641
notes: GENE_ASSOCIATION: YHR074W PROTEIN_ASSOCIATION: Qns1 SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 6.3.1.5

436421
stoichiometry: 1.0
species: 286183
type: SpeciesReference

410519
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298345
value: 0.0
type: LocalParameter

298498
value: 0.0
type: LocalParameter

345885
stoichiometry: 1.0
species: 283197
type: SpeciesReference

293617
value: 0.0
type: LocalParameter

292248
value: 0.0
type: LocalParameter

394491
stoichiometry: 1.0
species: 284586
type: SpeciesReference

291085
value: -999999.0
type: LocalParameter

436748
stoichiometry: 1.0
species: 284657
type: SpeciesReference

284726
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Reduced_glutathione_C10H16N3O6S
type: Species

301597
value: 0.0
type: LocalParameter

292187
value: 0.0
type: LocalParameter

415887
stoichiometry: 1.0
species: 284103
type: SpeciesReference

290538
kinetic law: 432850
name: R_serine_C_palmitoyltransferase
reactant: 432790
reactant: 432778
notes: GENE_ASSOCIATION: ( ( YDR062W and YMR296C ) and YBR058C-A ) PROTEIN_ASSOCIATION: ( Lcb and Tsc3 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS: 2.3.1.50
type: Reaction
product: 432838
product: 432814
product: 432826
reactant: 432802
reversible: false
fast: false

369812
stoichiometry: 1.0
species: 285604
type: SpeciesReference

439519
stoichiometry: 1.0
species: 286393
type: SpeciesReference

293201
value: 0.0
type: LocalParameter

381646
stoichiometry: 1.0
species: 285568
type: SpeciesReference

298499
value: 999999.0
type: LocalParameter

298346
value: 999999.0
type: LocalParameter

434668
stoichiometry: 1.0
species: 286090
type: SpeciesReference

303774
value: 999999.0
type: LocalParameter

291084
value: -0.098793
type: LocalParameter

293761
value: 0.0
type: LocalParameter

299428
value: 0.019085
type: LocalParameter

387707
stoichiometry: 1.0
species: 285637
type: SpeciesReference

388801
stoichiometry: 1.0
species: 284787
type: SpeciesReference

292035
value: 0.0
type: LocalParameter

301598
value: 0.0
type: LocalParameter

285568
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

283839
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_ATP_C10H12N5O13P3
type: Species

288653
kinetic law: 376407
product: 376394
reactant: 376382
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Formate_exchange
type: Reaction

362603
stoichiometry: 1.0
species: 285436
type: SpeciesReference

293200
value: 0.0
type: LocalParameter

412041
stoichiometry: 0.01
species: 285321
type: SpeciesReference

400410
stoichiometry: 1.0
species: 283830
type: SpeciesReference

293554
value: 0.0
type: LocalParameter

299423
value: 0.0
type: LocalParameter

292185
value: 0.0
type: LocalParameter

283359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_amino_1__5_phospho_D_ribosyl_imidazole_4_carboxylate_C9H11N3O9P
type: Species

387429
stoichiometry: 3.0
species: 285436
type: SpeciesReference

291087
value: 0.0
type: LocalParameter

293615
value: 0.0
type: LocalParameter

426691
stoichiometry: 1.0
species: 285399
type: SpeciesReference

298495
value: 0.0
type: LocalParameter

380136
stoichiometry: 1.0
species: 286552
type: SpeciesReference

394793
stoichiometry: 1.0
species: 284598
type: SpeciesReference

359843
stoichiometry: 1.0
species: 283833
type: SpeciesReference

378287
stoichiometry: 1.0
species: 285478
type: SpeciesReference

415393
stoichiometry: 1.0
species: 285751
type: SpeciesReference

285020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Isoleucyl_tRNA_Ile__C6H12NOR
type: Species

291086
value: 999999.0
type: LocalParameter

293767
value: 999999.0
type: LocalParameter

298497
value: 0.0
type: LocalParameter

375694
stoichiometry: 1.0
species: 284082
type: SpeciesReference

297828
value: 0.0
type: LocalParameter

288659
kinetic law: 376480
product: 376468
reactant: 376456
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Fumarate_exchange
type: Reaction

283941
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Methanethiol_CH4S
type: Species

299425
value: 999999.0
type: LocalParameter

351877
stoichiometry: 2.0
species: 284787
type: SpeciesReference

292183
value: 999999.0
type: LocalParameter

293552
value: 999999.0
type: LocalParameter

373787
stoichiometry: 0.015
species: 286405
type: SpeciesReference

285565
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_octanoate__n_C80__C8H15O2
type: Species

283836
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_ATP_C10H12N5O13P3
type: Species

292038
value: 999999.0
type: LocalParameter

283200
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__S__3_Methyl_2_oxopentanoate_C6H9O3
type: Species

298349
value: 0.0
type: LocalParameter

293613
value: 999999.0
type: LocalParameter

394299
stoichiometry: 1.0
species: 284592
type: SpeciesReference

442292
stoichiometry: 1.0
species: 284790
type: SpeciesReference

299581
value: 0.0
type: LocalParameter

432222
stoichiometry: 1.0
species: 284430
type: SpeciesReference

389077
stoichiometry: 0.01
species: 284430
type: SpeciesReference

284723
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Reduced_glutathione_C10H16N3O6S
type: Species

430867
stoichiometry: 1.0
species: 284787
type: SpeciesReference

375548
stoichiometry: 1.0
species: 284037
type: SpeciesReference

299424
value: 0.0
type: LocalParameter

405351
stoichiometry: 0.01
species: 285898
type: SpeciesReference

349906
stoichiometry: 1.0
species: 285754
type: SpeciesReference

303770
value: 0.014595
type: LocalParameter

405412
stoichiometry: 1.0
species: 284244
type: SpeciesReference

435260
stoichiometry: 1.0
species: 284760
type: SpeciesReference

421416
stoichiometry: 1.0
species: 284787
type: SpeciesReference

380402
stoichiometry: 1.0
species: 285372
type: SpeciesReference

298494
value: 0.0
type: LocalParameter

289510
reversible: false
kinetic law: 399626
name: R_Hydroxybenzoate_octaprenyltransferase__mitochondrial
type: Reaction
notes: GENE_ASSOCIATION: YNR041C PROTEIN_ASSOCIATION: Coq2-m SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
reactant: 399590
fast: false
reactant: 399578
product: 399614
product: 399602

297826
value: 0.0
type: LocalParameter

425568
stoichiometry: 1.0
species: 283350
type: SpeciesReference

428700
stoichiometry: 1.0
species: 285751
type: SpeciesReference

297822
value: 999999.0
type: LocalParameter

298490
value: 0.0
type: LocalParameter

299584
value: -0.023758
type: LocalParameter

379784
stoichiometry: 1.0
species: 287017
type: SpeciesReference

289950
reversible: false
reactant: 414062
product: 414074
reactant: 414050
name: R_NADH_dehydrogenase__cytosolicmitochondrial
notes: GENE_ASSOCIATION: ( YMR145C or YDL085W ) PROTEIN_ASSOCIATION: ( Nde1-m ) or ( Nde2-m ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.99.3
product: 414086
kinetic law: 414098
reactant: 414038
fast: false
type: Reaction

301418
value: -999999.0
type: LocalParameter

292241
value: 0.028496
type: LocalParameter

393935
stoichiometry: 1.0
species: 285796
type: SpeciesReference

390384
stoichiometry: 1.0
species: 283380
type: SpeciesReference

439725
stoichiometry: 1.0
species: 283104
type: SpeciesReference

303097
value: -999999.0
type: LocalParameter

348975
stoichiometry: 1.0
species: 284757
type: SpeciesReference

427622
stoichiometry: 1.0
species: 286069
type: SpeciesReference

289283
product: 392353
product: 392341
name: R_a_galactosidase__melibiose_
notes: GENE_ASSOCIATION: YBR184W PROTEIN_ASSOCIATION: Mel1 SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 3.2.1.22
kinetic law: 392366
reactant: 392329
type: Reaction
reactant: 392317
reversible: false
fast: false

299585
value: 0.0
type: LocalParameter

293209
value: -0.011879
type: LocalParameter

368710
stoichiometry: 2.0
species: 284757
type: SpeciesReference

295065
value: 0.0
type: LocalParameter

400844
stoichiometry: 1.0
species: 284796
type: SpeciesReference

297823
value: 0.0
type: LocalParameter

301417
value: 0.0
type: LocalParameter

288794
kinetic law: 378127
product: 378115
reactant: 378103
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_S_Methyl_L_methionine_exchange
type: Reaction

292393
value: 0.0
type: LocalParameter

285775
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

299586
value: 999999.0
type: LocalParameter

421863
stoichiometry: 1.0
species: 283404
type: SpeciesReference

297257
value: -0.096219
type: LocalParameter

302267
value: 0.0
type: LocalParameter

292018
value: -999999.0
type: LocalParameter

300602
value: 0.0
type: LocalParameter

303096
value: 0.0
type: LocalParameter

293556
value: 0.0
type: LocalParameter

298492
value: 999999.0
type: LocalParameter

297824
value: 0.0
type: LocalParameter

287113
name: R_3__4_hydroxyphenyl__lactate_formation
fast: false
kinetic law: 345088
product: 345076
reversible: false
reactant: 345027
product: 345064
reactant: 345052
type: Reaction
reactant: 345039
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:

299582
value: 0.0
type: LocalParameter

292243
value: 0.0
type: LocalParameter

285550
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octadecadienoate__n_C182__C18H31O2
type: Species

351041
stoichiometry: 1.0
species: 283713
type: SpeciesReference

302268
value: 0.0
type: LocalParameter

298491
value: -999999.0
type: LocalParameter

289281
product: 392293
kinetic law: 392305
reversible: false
fast: false
reactant: 392245
notes: GENE_ASSOCIATION: YBR020W PROTEIN_ASSOCIATION: Gal1 SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 2.7.1.6
product: 392281
reactant: 392257
product: 392269
name: R_galactokinase
type: Reaction

407262
stoichiometry: 1.0
species: 285140
type: SpeciesReference

356595
stoichiometry: 1.0
species: 285378
type: SpeciesReference

426364
stoichiometry: 1.0
species: 283359
type: SpeciesReference

403853
stoichiometry: 1.0
species: 285799
type: SpeciesReference

288797
kinetic law: 378165
product: 378152
reactant: 378140
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Sodium_exchange
type: Reaction

287112
kinetic law: 345015
product: 345003
reactant: 344991
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_phenylethanol_reversible_transport__mitochondrial
type: Reaction

284744
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Guanine_C5H5N5O
type: Species

295062
value: 0.0
type: LocalParameter

284805
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_H_H
type: Species

292395
value: 0.0
type: LocalParameter

303098
value: 999999.0
type: LocalParameter

378952
stoichiometry: 1.0
species: 286948
type: SpeciesReference

293558
value: 0.0
type: LocalParameter

297259
value: -999999.0
type: LocalParameter

388957
stoichiometry: 0.01
species: 284876
type: SpeciesReference

379084
stoichiometry: 1.0
species: 286015
type: SpeciesReference

288211
reactant: 368565
product: 368613
reactant: 368589
fast: false
reversible: false
product: 368625
reactant: 368601
reactant: 368577
name: R_Palmitoyl_CoA_desaturase__n_C160CoA___n_C161CoA_
product: 368637
notes: GENE_ASSOCIATION: YGL055W PROTEIN_ASSOCIATION: Ole1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 1.14.19.1
type: Reaction
kinetic law: 368649

369689
stoichiometry: 1.0
species: 285958
type: SpeciesReference

289954
fast: false
notes: GENE_ASSOCIATION: ( YJR049C or YEL041W or YPL188W ) PROTEIN_ASSOCIATION: ( Utr1 ) or ( Utr2 ) or ( Pos5 ) SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 2.7.1.23
product: 414206
product: 414230
name: R_NAD_kinase
reactant: 414182
reversible: false
type: Reaction
kinetic law: 414242
reactant: 414194
product: 414218

284808
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_H_H
type: Species

428930
stoichiometry: 1.0
species: 284708
type: SpeciesReference

289399
kinetic law: 396218
product: 396206
reactant: 396194
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_glyoxylate_transport
type: Reaction

375007
stoichiometry: 1.0
species: 283644
type: SpeciesReference

415188
stoichiometry: 1.0
species: 285751
type: SpeciesReference

293559
value: 0.0
type: LocalParameter

417826
stoichiometry: 1.0
species: 285751
type: SpeciesReference

293406
value: 0.0
type: LocalParameter

292991
value: 0.0
type: LocalParameter

365828
stoichiometry: 1.0
species: 284016
type: SpeciesReference

412586
stoichiometry: 1.0
species: 284757
type: SpeciesReference

293781
value: 0.076083
type: LocalParameter

362096
stoichiometry: 1.0
species: 283911
type: SpeciesReference

384348
stoichiometry: 7.0
species: 284754
type: SpeciesReference

301300
value: 0.0
type: LocalParameter

299589
value: 0.0
type: LocalParameter

292886
value: 999999.0
type: LocalParameter

410748
stoichiometry: 1.0
species: 284787
type: SpeciesReference

426050
stoichiometry: 1.0
species: 285745
type: SpeciesReference

301413
value: 0.0
type: LocalParameter

293205
value: 0.0
type: LocalParameter

289287
reversible: true
reactant: 392462
kinetic law: 392510
fast: false
name: R_UTP_glucose_1_phosphate_uridylyltransferase
notes: GENE_ASSOCIATION: ( YKL035W or YHL012W ) PROTEIN_ASSOCIATION: ( Ugp1 ) or ( Ugp2 ) SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 2.7.7.9
reactant: 392450
type: Reaction
product: 392486
reactant: 392474
product: 392498

291092
value: 0.0
type: LocalParameter

288214
product: 368710
product: 368722
kinetic law: 368746
name: R_stearoyl_CoA_desaturase__n_C180CoA___n_C181CoA_
type: Reaction
reactant: 368697
reactant: 368673
reactant: 368661
reversible: false
notes: GENE_ASSOCIATION: YGL055W PROTEIN_ASSOCIATION: Ole1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 1.14.19.1
fast: false
reactant: 368685
product: 368734

292992
value: 0.0
type: LocalParameter

357810
stoichiometry: 1.0
species: 284618
type: SpeciesReference

290522
name: R_sphingoid_base_phosphate_phosphatase__phytosphingosine_1_phosphate___endoplasmic_reticulum
type: Reaction
kinetic law: 432367
reactant: 432319
reactant: 432331
notes: GENE_ASSOCIATION: ( YJL134W or YKR053C ) PROTEIN_ASSOCIATION: ( Lcb3-er ) or ( Ysr3-er ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
fast: false
product: 432355
reversible: false
product: 432343

366405
stoichiometry: 1.0
species: 285955
type: SpeciesReference

435755
stoichiometry: 1.0
species: 286135
type: SpeciesReference

292244
value: -999999.0
type: LocalParameter

289397
kinetic law: 396182
product: 396170
reactant: 396158
notes: GENE_ASSOCIATION: YPR021C PROTEIN_ASSOCIATION: Agc1-m SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_Glutamate_transport__uniporter___mitochondrial
type: Reaction

301416
value: 0.0
type: LocalParameter

358342
stoichiometry: 1.0
species: 284618
type: SpeciesReference

292391
value: 999999.0
type: LocalParameter

289952
kinetic law: 414170
reactant: 414110
name: R_NADH_dehydrogenase__mitochondrial
reactant: 414134
product: 414158
product: 414146
notes: GENE_ASSOCIATION: ( YML120C or YKL192C ) PROTEIN_ASSOCIATION: ( Ndi1-m ) or ( Acp1-m ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.99.3
reactant: 414122
fast: false
type: Reaction
reversible: false

348651
stoichiometry: 1.0
species: 283608
type: SpeciesReference

426787
stoichiometry: 1.0
species: 286342
type: SpeciesReference

303789
value: 0.0
type: LocalParameter

443694
stoichiometry: 0.0234
species: 286258
type: SpeciesReference

297820
value: 0.0
type: LocalParameter

349374
stoichiometry: 1.0
species: 284754
type: SpeciesReference

300603
value: 0.0
type: LocalParameter

380981
stoichiometry: 1.0
species: 285775
type: SpeciesReference

293408
value: 0.0
type: LocalParameter

347396
stoichiometry: 1.0
species: 283641
type: SpeciesReference

433189
stoichiometry: 1.0
species: 286024
type: SpeciesReference

284741
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Guanine_C5H5N5O
type: Species

441494
stoichiometry: 1.0
species: 284732
type: SpeciesReference

413526
stoichiometry: 1.0
species: 284796
type: SpeciesReference

293783
value: 0.0
type: LocalParameter

292888
value: 0.0
type: LocalParameter

285772
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Phosphate_HO4P
type: Species

288791
kinetic law: 378091
product: 378078
reactant: 378066
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Methionine_exchange
type: Reaction

431919
stoichiometry: 1.0
species: 283425
type: SpeciesReference

293207
value: 0.0
type: LocalParameter

289285
name: R_galactose_1_phosphate_uridylyltransferase
product: 392414
kinetic law: 392438
reversible: true
product: 392426
reactant: 392402
type: Reaction
reactant: 392390
reactant: 392378
fast: false
notes: GENE_ASSOCIATION: YBR018C PROTEIN_ASSOCIATION: Gal7 SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 2.7.7.10

344263
stoichiometry: 1.0
species: 283074
type: SpeciesReference

430273
stoichiometry: 1.0
species: 284757
type: SpeciesReference

291090
value: 0.0
type: LocalParameter

303788
value: 999999.0
type: LocalParameter

411340
stoichiometry: 1.0
species: 285306
type: SpeciesReference

300604
value: 0.0
type: LocalParameter

290520
reactant: 432258
notes: GENE_ASSOCIATION: ( YJL134W or YKR053C ) PROTEIN_ASSOCIATION: ( Lcb3-er ) or ( Ysr3-er ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
type: Reaction
product: 432283
product: 432295
reactant: 432271
name: R_sphingoid_base_phosphate_phosphatase__sphinganine_1_phosphatase___endoplasmic_reticulum
reversible: false
fast: false
kinetic law: 432307

292246
value: 999999.0
type: LocalParameter

442860
stoichiometry: 0.02
species: 284828
type: SpeciesReference

299588
value: 0.0
type: LocalParameter

374946
stoichiometry: 1.0
species: 286618
type: SpeciesReference

298790
value: 999999.0
type: LocalParameter

292994
value: 999999.0
type: LocalParameter

301301
value: 0.0
type: LocalParameter

410531
stoichiometry: 1.0
species: 285264
type: SpeciesReference

293784
value: 0.0
type: LocalParameter

414629
stoichiometry: 1.0
species: 283830
type: SpeciesReference

284954
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isoamyl_acetate_C7H14O2
type: Species

288992
fast: false
reversible: true
product: 380654
type: Reaction
product: 380667
reactant: 380642
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 3.1.2.14
product: 380679
kinetic law: 380692
reactant: 380630
name: R_fatty_acyl_ACP_hydrolase

298793
value: 0.0
type: LocalParameter

302113
value: 0.0
type: LocalParameter

297103
value: 0.0
type: LocalParameter

289682
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reactant: 404977
fast: false
product: 404989
reactant: 404965
name: R_inositol_phosphorylceramide__ceramide_3__26C__phospholipase_C
kinetic law: 405025
product: 405013
type: Reaction
product: 405001
reversible: false

293402
value: 0.0
type: LocalParameter

288373
kinetic law: 372073
name: R_D_lactate_dehydrogenase__mitochondrial
product: 372061
product: 372049
reversible: false
reactant: 372025
notes: GENE_ASSOCIATION: ( ( YJR048W and YDL178W ) or ( YEL039C and YDL178W ) ) PROTEIN_ASSOCIATION: ( Cyc1-m and Dld2-m ) or ( Cyc7-m and Dld2-m ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 1.1.2.4
fast: false
reactant: 372037
type: Reaction

387864
stoichiometry: 3.0
species: 284757
type: SpeciesReference

290630
product: 435924
type: Reaction
reversible: false
reactant: 435876
product: 435912
kinetic law: 435960
reactant: 435900
fast: false
name: R_Taurcholate_via_ABC_system__vacuolar_
notes: GENE_ASSOCIATION: YLL048C PROTEIN_ASSOCIATION: Ybt1-v SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
product: 435948
product: 435936
reactant: 435888

288217
product: 368818
type: Reaction
product: 368830
reactant: 368758
fast: false
name: R_Oleoyl_CoA_desaturase__n_C181CoA___n_C182CoA_
reactant: 368770
reactant: 368794
kinetic law: 368842
product: 368806
reactant: 368782
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 1.14.19.1
reversible: false

395675
stoichiometry: 1.0
species: 284595
type: SpeciesReference

396628
stoichiometry: 1.0
species: 284757
type: SpeciesReference

406644
stoichiometry: 0.655
species: 284840
type: SpeciesReference

425580
stoichiometry: 1.0
species: 284052
type: SpeciesReference

386070
stoichiometry: 1.0
species: 283992
type: SpeciesReference

289395
reactant: 396109
product: 396122
reactant: 396097
reversible: false
name: R_L_glutamate_transport_out_via_proton_symport__vacuolar
kinetic law: 396146
type: Reaction
fast: false
notes: GENE_ASSOCIATION: YER119C PROTEIN_ASSOCIATION: Avt6-v SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
product: 396134

301305
value: 0.0
type: LocalParameter

428821
stoichiometry: 1.0
species: 285751
type: SpeciesReference

292996
value: 0.0
type: LocalParameter

298792
value: 0.0
type: LocalParameter

357967
stoichiometry: 1.0
species: 286282
type: SpeciesReference

302114
value: 0.0
type: LocalParameter

292883
value: 0.0
type: LocalParameter

283434
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Cystine_C6H12N2O4S2
type: Species

297104
value: 0.0
type: LocalParameter

283587
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Adenine_C5H5N5
type: Species

375115
stoichiometry: 1.0
species: 283686
type: SpeciesReference

421536
stoichiometry: 1.0
species: 283602
type: SpeciesReference

435380
stoichiometry: 3.0
species: 284757
type: SpeciesReference

424604
stoichiometry: 1.0
species: 285291
type: SpeciesReference

397041
stoichiometry: 1.0
species: 284796
type: SpeciesReference

301304
value: 999999.0
type: LocalParameter

369799
stoichiometry: 1.0
species: 284747
type: SpeciesReference

293314
value: 0.0
type: LocalParameter

366513
stoichiometry: 1.0
species: 284757
type: SpeciesReference

292884
value: -999999.0
type: LocalParameter

401505
stoichiometry: 1.0
species: 284013
type: SpeciesReference

302260
value: 0.0
type: LocalParameter

283209
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxodecanoyl_CoA_C31H48N7O18P3S
type: Species

300607
value: 999999.0
type: LocalParameter

283431
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Cystine_C6H12N2O4S2
type: Species

293404
value: 999999.0
type: LocalParameter

283584
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Adenine_C5H5N5
type: Species

303091
value: 999999.0
type: LocalParameter

289680
kinetic law: 404953
product: 404929
reactant: 404905
name: R_inositol_phosphorylceramide__ceramide_3__24C__phospholipase_C
type: Reaction
fast: false
product: 404941
reactant: 404893
product: 404917
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reversible: false

433298
stoichiometry: 1.0
species: 285436
type: SpeciesReference

303897
value: 0.0
type: LocalParameter

303898
value: 0.0
type: LocalParameter

393113
stoichiometry: 1.0
species: 284556
type: SpeciesReference

302116
value: 0.0
type: LocalParameter

293101
value: 0.0
type: LocalParameter

288995
kinetic law: 380728
product: 380716
reactant: 380704
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport
type: Reaction

348542
stoichiometry: 1.0
species: 284013
type: SpeciesReference

414776
stoichiometry: 1.0
species: 284799
type: SpeciesReference

287266
fast: false
kinetic law: 347869
reactant: 347821
reversible: false
name: R_acetyl_CoA_C_acyltransferase__decanoyl_CoA___peroxisomal
product: 347857
reactant: 347833
product: 347845
type: Reaction
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16

420496
stoichiometry: 1.0
species: 284757
type: SpeciesReference

298796
value: 0.0
type: LocalParameter

301412
value: 999999.0
type: LocalParameter

415077
stoichiometry: 1.0
species: 284757
type: SpeciesReference

289393
reactant: 396035
reversible: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
product: 396060
product: 396073
kinetic law: 396085
type: Reaction
name: R_L_glutamate_transport_into_mitochondria_via_hydroxide_ion_antiport
fast: false
reactant: 396048

375404
stoichiometry: 1.0
species: 283863
type: SpeciesReference

302261
value: 0.0
type: LocalParameter

300608
value: 0.0
type: LocalParameter

292998
value: 0.0
type: LocalParameter

288376
fast: false
reversible: true
notes: GENE_ASSOCIATION: YKL217W PROTEIN_ASSOCIATION: Jen1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reactant: 372097
kinetic law: 372134
product: 372110
type: Reaction
reactant: 372085
product: 372122
name: R_D_lactate_transport_via_proton_symport

297106
value: -0.238964
type: LocalParameter

284514
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_sn_Glycero_3_phospho_1_inositol_C9H18O11P
type: Species

429461
stoichiometry: 1.0
species: 283830
type: SpeciesReference

303896
value: -0.076169
type: LocalParameter

400579
stoichiometry: 1.0
species: 284787
type: SpeciesReference

411497
stoichiometry: 1.0
species: 284523
type: SpeciesReference

303090
value: 0.0
type: LocalParameter

344372
stoichiometry: 1.0
species: 283023
type: SpeciesReference

357750
stoichiometry: 1.0
species: 283830
type: SpeciesReference

302117
value: 0.0
type: LocalParameter

294939
value: 0.0
type: LocalParameter

293102
value: -999999.0
type: LocalParameter

371650
stoichiometry: 1.0
species: 284301
type: SpeciesReference

297930
value: 999999.0
type: LocalParameter

289289
reactant: 392534
kinetic law: 392571
fast: false
reactant: 392522
product: 392559
name: R_D_galactose_transport_in_via_proton_symport
notes: GENE_ASSOCIATION: ( YLR081W or YFL011W or YOL156W or YNL318C or YJL219W or YDR536W ) PROTEIN_ASSOCIATION: ( Gal2 ) or ( Hxt10 ) or ( Hxt11 ) or ( Hxt14 ) or ( Hxt9 ) or ( Stl1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
type: Reaction
product: 392546
reversible: false

293316
value: 6.33E-4
type: LocalParameter

439060
stoichiometry: 1.0
species: 286372
type: SpeciesReference

384120
stoichiometry: 8.0
species: 284025
type: SpeciesReference

407335
stoichiometry: 1.0
species: 285149
type: SpeciesReference

298795
value: -0.017521
type: LocalParameter

375984
stoichiometry: 1.0
species: 284310
type: SpeciesReference

285778
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

404483
stoichiometry: 1.0
species: 285056
type: SpeciesReference

303093
value: 0.0
type: LocalParameter

388371
stoichiometry: 1.0
species: 285562
type: SpeciesReference

300758
value: 0.0
type: LocalParameter

298059
value: 0.0
type: LocalParameter

283437
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Formylkynurenine_C11H12N2O4
type: Species

292398
value: 0.0
type: LocalParameter

390275
stoichiometry: 1.0
species: 284487
type: SpeciesReference

295068
value: 0.0
type: LocalParameter

396725
stoichiometry: 1.0
species: 283602
type: SpeciesReference

400276
stoichiometry: 1.0
species: 284766
type: SpeciesReference

352982
stoichiometry: 1.0
species: 283632
type: SpeciesReference

298798
value: 0.0
type: LocalParameter

427137
stoichiometry: 1.0
species: 283998
type: SpeciesReference

287119
reactant: 345160
reversible: true
kinetic law: 345208
type: Reaction
fast: false
product: 345184
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
reactant: 345172
product: 345196
name: R_3__4_hydroxyphenyl_pyruvate_mitochondrial_transport_via_proton_symport

301309
value: -0.015839
type: LocalParameter

362700
stoichiometry: 1.0
species: 283902
type: SpeciesReference

426256
stoichiometry: 1.0
species: 285751
type: SpeciesReference

297931
value: 0.0
type: LocalParameter

289391
name: R_L_glutamate_transport_via_proton_symport__reversible
reactant: 395987
notes: GENE_ASSOCIATION: ( YFL055W or YDR536W or YKR039W or YCL025C or YPL265W ) PROTEIN_ASSOCIATION: ( Agp3 ) or ( Stl1 ) or ( Gap1 ) or ( Agp1 ) or ( Dip5 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 396011
reactant: 395975
fast: false
product: 395999
type: Reaction
kinetic law: 396023
reversible: true

297251
value: 0.0
type: LocalParameter

430163
stoichiometry: 1.0
species: 285949
type: SpeciesReference

288370
product: 372001
reversible: false
kinetic law: 372013
reactant: 371977
reactant: 371965
name: R_D_lactate_dehydrogenase__cytosolicmitochondrial
fast: false
type: Reaction
product: 371989
notes: GENE_ASSOCIATION: ( ( YJR048W and YDL174C ) or ( YEL039C and YDL174C ) or ( YJR048W and YEL071W ) or ( YEL039C and YEL071W ) ) PROTEIN_ASSOCIATION: ( Cyc1-m and Dld1-m ) or ( Cyc7-m and Dld1-m ) or ( Cyc1-m and Dld3 ) or ( Cyc7-m and Dld3 ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.2.4

297100
value: 0.0
type: LocalParameter

300759
value: 999999.0
type: LocalParameter

302263
value: 0.0
type: LocalParameter

302110
value: 0.0
type: LocalParameter

298058
value: -0.009305
type: LocalParameter

380873
stoichiometry: 1.0
species: 284757
type: SpeciesReference

292397
value: -0.045734
type: LocalParameter

345328
stoichiometry: 1.0
species: 283131
type: SpeciesReference

375838
stoichiometry: 1.0
species: 284163
type: SpeciesReference

298797
value: 999999.0
type: LocalParameter

293104
value: 999999.0
type: LocalParameter

293318
value: 0.0
type: LocalParameter

293839
value: 0.0
type: LocalParameter

301308
value: 0.0
type: LocalParameter

379676
stoichiometry: 1.0
species: 287008
type: SpeciesReference

295069
value: 0.0
type: LocalParameter

380570
stoichiometry: 1.0
species: 286153
type: SpeciesReference

360185
stoichiometry: 1.0
species: 283602
type: SpeciesReference

302111
value: 999999.0
type: LocalParameter

384023
stoichiometry: 1.0
species: 284849
type: SpeciesReference

302264
value: 0.0
type: LocalParameter

383394
stoichiometry: 1.0
species: 283722
type: SpeciesReference

357209
stoichiometry: 1.0
species: 283836
type: SpeciesReference

297254
value: 0.0
type: LocalParameter

376602
stoichiometry: 1.0
species: 284538
type: SpeciesReference

302050
value: 999999.0
type: LocalParameter

284511
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_sn_Glycero_3_phosphocholine_C8H20NO6P
type: Species

284802
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_H_H
type: Species

297933
value: 0.0
type: LocalParameter

400736
stoichiometry: 1.0
species: 284888
type: SpeciesReference

293319
value: 0.0
type: LocalParameter

297253
value: 999999.0
type: LocalParameter

417932
stoichiometry: 2.0
species: 284757
type: SpeciesReference

381030
stoichiometry: 1.0
species: 284808
type: SpeciesReference

302265
value: 999999.0
type: LocalParameter

303094
value: 0.0
type: LocalParameter

293401
value: 0.0
type: LocalParameter

300757
value: -0.199368
type: LocalParameter

292881
value: 0.0
type: LocalParameter

283581
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_gamma_Amino_gamma_cyanobutanoate_C5H8N2O2
type: Species

297255
value: 0.0
type: LocalParameter

297102
value: 999999.0
type: LocalParameter

363144
stoichiometry: 1.0
species: 284013
type: SpeciesReference

302051
value: 0.0
type: LocalParameter

403745
stoichiometry: 1.0
species: 283713
type: SpeciesReference

287116
reversible: false
fast: false
name: R_4_Hydroxyphenylpyruvateoxygen_oxidoreductase
product: 345124
kinetic law: 345148
product: 345136
reactant: 345112
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.13.11.27
type: Reaction
reactant: 345100

297934
value: 0.0
type: LocalParameter

287269
product: 347906
name: R_acetyl_CoA_C_acetyltransferase__dodecanoyl___peroxisomal
fast: false
reactant: 347894
kinetic law: 347930
reactant: 347882
reversible: false
type: Reaction
product: 347918
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16

288998
kinetic law: 380825
product: 380789
product: 380777
reactant: 380752
reversible: false
type: Reaction
fast: false
reactant: 380765
reactant: 380740
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
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product: 380813
product: 380801

293106
value: 0.0
type: LocalParameter

435152
stoichiometry: 1.0
species: 286111
type: SpeciesReference

442195
stoichiometry: 1.0
species: 286513
type: SpeciesReference

410639
stoichiometry: 1.0
species: 285285
type: SpeciesReference

368890
stoichiometry: 1.0
species: 283398
type: SpeciesReference

298065
value: 0.0
type: LocalParameter

435489
stoichiometry: 1.0
species: 284766
type: SpeciesReference

390917
stoichiometry: 1.0
species: 284493
type: SpeciesReference

302041
value: 0.0
type: LocalParameter

430987
stoichiometry: 1.0
species: 286249
type: SpeciesReference

422273
stoichiometry: 1.0
species: 285745
type: SpeciesReference

399937
stoichiometry: 1.0
species: 284004
type: SpeciesReference

418065
stoichiometry: 2.0
species: 284757
type: SpeciesReference

292802
value: 0.0
type: LocalParameter

379338
stoichiometry: 1.0
species: 286096
type: SpeciesReference

303890
value: -0.029697
type: LocalParameter

300767
value: 999999.0
type: LocalParameter

429245
stoichiometry: 1.0
species: 285487
type: SpeciesReference

368155
stoichiometry: 1.0
species: 284313
type: SpeciesReference

284508
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_sn_Glycero_3_phosphocholine_C8H20NO6P
type: Species

290638
product: 436227
product: 436215
reactant: 436190
reactant: 436202
name: R_hydrogen_peroxide_reductase__thioredoxin___mitochondrial
fast: false
kinetic law: 436239
type: Reaction
notes: GENE_ASSOCIATION: ( YBL064C and YCR083W ) PROTEIN_ASSOCIATION: ( Prx1-m and Trx3-m ) SUBSYSTEM: S_Other PROTEIN_CLASS:
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369936
stoichiometry: 1.0
species: 284766
type: SpeciesReference

289526
reactant: 400107
type: Reaction
reactant: 400119
reversible: true
kinetic law: 400155
product: 400131
name: R_Homocysteine_peroxisomal_transport_via_proton_symport
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
product: 400143

425689
stoichiometry: 1.0
species: 283101
type: SpeciesReference

297923
value: 999999.0
type: LocalParameter

415297
stoichiometry: 1.0
species: 284757
type: SpeciesReference

298066
value: 999999.0
type: LocalParameter

299431
value: 0.0
type: LocalParameter

407116
stoichiometry: 1.0
species: 283836
type: SpeciesReference

285035
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Indole_3_acetate_C10H8NO2
type: Species

283215
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxohexadecanoyl_CoA_C37H60N7O18P3S
type: Species

302040
value: 0.0
type: LocalParameter

293620
value: 0.0
type: LocalParameter

293834
value: -999999.0
type: LocalParameter

299432
value: 999999.0
type: LocalParameter

283956
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Choline_phosphate_C5H13NO4P
type: Species

359855
stoichiometry: 2.0
species: 284793
type: SpeciesReference

292803
value: 0.0
type: LocalParameter

303891
value: -999999.0
type: LocalParameter

300766
value: 0.0
type: LocalParameter

283368
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_5_Amino_4_oxopentanoate_C5H9NO3
type: Species

289678
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
kinetic law: 404881
product: 404844
name: R_inositol_phosphorylceramide__ceramide_2__26C__phospholipase_C
reactant: 404819
type: Reaction
reversible: false
product: 404868
product: 404856
fast: false
reactant: 404832

413673
stoichiometry: 1.0
species: 285360
type: SpeciesReference

391050
stoichiometry: 1.0
species: 284565
type: SpeciesReference

371432
stoichiometry: 1.0
species: 284757
type: SpeciesReference

297926
value: 0.0
type: LocalParameter

285038
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indole_3_acetonitrile_C10H8N2
type: Species

299430
value: 0.0
type: LocalParameter

283959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_chorismate_C10H8O6
type: Species

346319
stoichiometry: 1.0
species: 283299
type: SpeciesReference

298068
value: 0.0
type: LocalParameter

283428
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_2_Aminoadipate_C6H10NO4
type: Species

293837
value: 999999.0
type: LocalParameter

406042
stoichiometry: 1.0
species: 283440
type: SpeciesReference

293623
value: 999999.0
type: LocalParameter

300765
value: -0.011879
type: LocalParameter

302043
value: 999999.0
type: LocalParameter

423224
stoichiometry: 0.01
species: 283893
type: SpeciesReference

293982
value: 0.0
type: LocalParameter

384540
stoichiometry: 8.0
species: 284778
type: SpeciesReference

289524
notes: GENE_ASSOCIATION: ( YPL273W or YLL062C ) PROTEIN_ASSOCIATION: ( Sam4 ) or ( Mht1 ) SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 2.1.1.10
type: Reaction
product: 400083
reversible: false
fast: false
product: 400059
kinetic law: 400095
reactant: 400047
name: R_homocysteine_S_methyltransferase
product: 400071
reactant: 400035

395459
stoichiometry: 1.0
species: 284586
type: SpeciesReference

292805
value: 999999.0
type: LocalParameter

396945
stoichiometry: 1.0
species: 286303
type: SpeciesReference

297925
value: 0.0
type: LocalParameter

298069
value: 0.0
type: LocalParameter

363580
stoichiometry: 1.0
species: 285487
type: SpeciesReference

283845
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_ATP_C10H12N5O13P3
type: Species

396206
stoichiometry: 1.0
species: 284651
type: SpeciesReference

351733
stoichiometry: 1.0
species: 283713
type: SpeciesReference

290636
fast: false
type: Reaction
reactant: 436129
product: 436154
reversible: false
notes: GENE_ASSOCIATION: ( ( YLR043C and YDR453C ) or ( YGR209C and YDR453C ) ) PROTEIN_ASSOCIATION: ( Trx1 and Tsa2 ) or ( Trx2 and Tsa2 ) SUBSYSTEM: S_Other PROTEIN_CLASS:
kinetic law: 436178
reactant: 436141
name: R_hydrogen_peroxide_reductase__thioredoxin_
product: 436166

294932
value: 0.0
type: LocalParameter

348277
stoichiometry: 1.0
species: 283602
type: SpeciesReference

298061
value: 0.0
type: LocalParameter

297928
value: 0.0
type: LocalParameter

300762
value: 0.0
type: LocalParameter

401085
stoichiometry: 1.0
species: 284915
type: SpeciesReference

288367
reactant: 371893
notes: GENE_ASSOCIATION: YHR068W PROTEIN_ASSOCIATION: Dys1 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.99.6
reversible: false
product: 371917
fast: false
name: R_deoxyhypusine_synthase__cytosolicmitochondrial
kinetic law: 371953
type: Reaction
product: 371941
reactant: 371881
reactant: 371905
product: 371929

289676
product: 404795
product: 404771
kinetic law: 404807
product: 404783
type: Reaction
reactant: 404747
reversible: false
fast: false
reactant: 404759
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
name: R_inositol_phosphorylceramide__ceramide_2__24C__phospholipase_C

344701
stoichiometry: 1.0
species: 283044
type: SpeciesReference

404264
stoichiometry: 1.0
species: 285041
type: SpeciesReference

283365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_5_Amino_4_oxopentanoate_C5H9NO3
type: Species

300763
value: 0.0
type: LocalParameter

303894
value: 0.0
type: LocalParameter

433093
stoichiometry: 1.0
species: 284466
type: SpeciesReference

436869
stoichiometry: 1.0
species: 286210
type: SpeciesReference

297108
value: 0.0
type: LocalParameter

293831
value: -0.189972
type: LocalParameter

441058
stoichiometry: 1.0
species: 286456
type: SpeciesReference

294938
value: 0.0
type: LocalParameter

302118
value: 999999.0
type: LocalParameter

293321
value: 999999.0
type: LocalParameter

289674
product: 404723
type: Reaction
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
name: R_inositol_phosphorylceramide__ceramide_1__26C__phospholipase_C
reactant: 404674
product: 404710
reactant: 404686
kinetic law: 404735
fast: false
product: 404698
reversible: false

348868
stoichiometry: 1.0
species: 284961
type: SpeciesReference

284505
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glyceraldehyde_3_phosphate_C3H5O6P
type: Species

290634
type: Reaction
fast: false
reactant: 436056
product: 436093
product: 436105
reversible: true
kinetic law: 436117
product: 436080
name: R_TetrahydrofolateL_glutamate_gamma_ligase__ADP_forming_
reactant: 436032
notes: GENE_ASSOCIATION: ( YKL132C or YOR241W or YMR113W ) PROTEIN_ASSOCIATION: ( Rma1 ) or ( Met7 ) or ( Fol3 ) SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 6.3.2.17
reactant: 436044
product: 436068

302044
value: 0.0
type: LocalParameter

287275
product: 348035
reversible: false
name: R_acetyl_CoA_acyltransferase__hexadecanoyl_CoA___peroxisomal
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16
reactant: 348009
fast: false
type: Reaction
product: 348048
kinetic law: 348061
reactant: 348022

420568
stoichiometry: 1.0
species: 284787
type: SpeciesReference

374838
stoichiometry: 1.0
species: 286609
type: SpeciesReference

423368
stoichiometry: 1.0
species: 285751
type: SpeciesReference

298063
value: 0.0
type: LocalParameter

349204
stoichiometry: 1.0
species: 284754
type: SpeciesReference

356220
stoichiometry: 1.0
species: 285973
type: SpeciesReference

355097
stoichiometry: 1.0
species: 284999
type: SpeciesReference

363217
stoichiometry: 1.0
species: 284022
type: SpeciesReference

294935
value: -0.031838
type: LocalParameter

352550
stoichiometry: 1.0
species: 286171
type: SpeciesReference

302047
value: -0.011879
type: LocalParameter

293833
value: 0.0
type: LocalParameter

292800
value: 0.0
type: LocalParameter

287272
kinetic law: 347996
product: 347969
reactant: 347956
name: R_acetyl_CoA_acyltransferase__tetradecanoyl_CoA___peroxisomal
reversible: false
product: 347983
reactant: 347943
fast: false
type: Reaction
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16

292020
value: 999999.0
type: LocalParameter

283218
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxooctadecanoyl_CoA_C39H64N7O18P3S
type: Species

283842
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_ATP_C10H12N5O13P3
type: Species

384456
stoichiometry: 9.0
species: 283530
type: SpeciesReference

403961
stoichiometry: 1.0
species: 284787
type: SpeciesReference

297929
value: -999999.0
type: LocalParameter

298064
value: -0.009305
type: LocalParameter

293323
value: 0.0
type: LocalParameter

298331
value: -0.011285
type: LocalParameter

363362
stoichiometry: 1.0
species: 284787
type: SpeciesReference

345641
stoichiometry: 1.0
species: 283020
type: SpeciesReference

443211
stoichiometry: 1.0E-6
species: 283866
type: SpeciesReference

353465
stoichiometry: 1.0
species: 285436
type: SpeciesReference

289528
kinetic law: 400191
product: 400179
reactant: 400167
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_Hexadecanoate__n_C160__transport_in_via_uniport
type: Reaction

303893
value: 999999.0
type: LocalParameter

350352
stoichiometry: 1.0
species: 284790
type: SpeciesReference

302046
value: 0.0
type: LocalParameter

289672
name: R_inositol_phosphorylceramide__ceramide_1__24C__phospholipase_C
product: 404625
notes: GENE_ASSOCIATION: YER019W PROTEIN_ASSOCIATION: Isc1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
type: Reaction
product: 404637
reversible: false
fast: false
kinetic law: 404662
reactant: 404599
product: 404649
reactant: 404612

419445
stoichiometry: 1.0
species: 285796
type: SpeciesReference

290632
kinetic law: 436020
notes: GENE_ASSOCIATION: ( YDR019C and YMR189W and YAL044C and ( YBR221C and YER178W ) ) PROTEIN_ASSOCIATION: ( Gcv1-m and Gcv2-m and Gcv3-m and PdE1-m ) SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 2.1.2.10
type: Reaction
product: 436008
reactant: 435972
product: 435996
reactant: 435984
reversible: false
fast: false
name: R_tetrahydrofolate_aminomethyltransferase__mitochondrial

298332
value: -999999.0
type: LocalParameter

283362
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_Amino_4_oxopentanoate_C5H9NO3
type: Species

293985
value: 0.0038
type: LocalParameter

391761
stoichiometry: 1.0
species: 285751
type: SpeciesReference

293988
value: 0.0
type: LocalParameter

293774
value: 0.0
type: LocalParameter

292022
value: 0.0
type: LocalParameter

284738
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Guanine_C5H5N5O
type: Species

298486
value: 999999.0
type: LocalParameter

298333
value: 999999.0
type: LocalParameter

290526
product: 432500
product: 432487
fast: false
type: Reaction
kinetic law: 432512
reactant: 432451
notes: GENE_ASSOCIATION: YJR159W PROTEIN_ASSOCIATION: Sor1 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.14
reactant: 432463
name: R_L_sorbitol_dehydrogenase__L_sorbose_producing_
product: 432475
reversible: false

303785
value: 0.0
type: LocalParameter

411909
stoichiometry: 1.0
species: 285234
type: SpeciesReference

293629
value: -0.429027
type: LocalParameter

415875
stoichiometry: 1.0
species: 283602
type: SpeciesReference

374729
stoichiometry: 1.0
species: 286600
type: SpeciesReference

420908
stoichiometry: 1.0
species: 284747
type: SpeciesReference

293773
value: 0.0
type: LocalParameter

292176
value: 0.0
type: LocalParameter

387719
stoichiometry: 1.0
species: 283419
type: SpeciesReference

285556
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

302048
value: 0.0
type: LocalParameter

348759
stoichiometry: 1.0
species: 284796
type: SpeciesReference

298334
value: 0.0
type: LocalParameter

298487
value: 0.0
type: LocalParameter

284961
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Isoamyl_alcohol_C5H12O
type: Species

303786
value: 0.0
type: LocalParameter

434656
stoichiometry: 1.0
species: 286087
type: SpeciesReference

292237
value: 999999.0
type: LocalParameter

289958
product: 414363
name: R_NAD_nucleosidase
reactant: 414339
product: 414351
product: 414375
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 3.2.2.5
kinetic law: 414387
fast: false
reversible: false
reactant: 414327
type: Reaction

293212
value: 999999.0
type: LocalParameter

400422
stoichiometry: 1.0
species: 283335
type: SpeciesReference

297818
value: -0.192438
type: LocalParameter

288641
kinetic law: 376261
product: 376249
reactant: 376236
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Fe2_exchange
type: Reaction

293562
value: 999999.0
type: LocalParameter

292024
value: 0.0
type: LocalParameter

378734
stoichiometry: 1.0
species: 286930
type: SpeciesReference

350787
stoichiometry: 1.0
species: 284790
type: SpeciesReference

299439
value: 999999.0
type: LocalParameter

282899
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_1_3_beta_D_Glucan_C6H10O5
type: Species

397149
stoichiometry: 1.0
species: 284757
type: SpeciesReference

391653
stoichiometry: 1.0
species: 282938
type: SpeciesReference

291095
value: 0.0
type: LocalParameter

290524
fast: false
product: 432403
notes: GENE_ASSOCIATION: YJR159W PROTEIN_ASSOCIATION: Sor1 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.14
type: Reaction
reactant: 432391
name: R_D_sorbitol_dehydrogenase__D_fructose_producing_
reactant: 432379
product: 432415
reversible: false
kinetic law: 432439
product: 432427

378807
stoichiometry: 1.0
species: 286936
type: SpeciesReference

284962
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Isoamyl_alcohol_C5H12O
type: Species

285559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

407480
stoichiometry: 1.0
species: 283242
type: SpeciesReference

406764
stoichiometry: 1.0
species: 284757
type: SpeciesReference

356377
stoichiometry: 1.0
species: 284618
type: SpeciesReference

288644
kinetic law: 376297
product: 376285
reactant: 376273
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_fecosterol_exchange
type: Reaction

357077
stoichiometry: 1.0
species: 284787
type: SpeciesReference

292178
value: 0.015001
type: LocalParameter

299438
value: 0.0
type: LocalParameter

293989
value: -999999.0
type: LocalParameter

298336
value: 0.221001
type: LocalParameter

283950
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Choline_C5H14NO
type: Species

291094
value: 999999.0
type: LocalParameter

303784
value: 0.0
type: LocalParameter

298489
value: 0.0
type: LocalParameter

292239
value: 0.0
type: LocalParameter

435609
stoichiometry: 0.05
species: 285529
type: SpeciesReference

284963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Isoamyl_alcohol_C5H12O
type: Species

419336
stoichiometry: 1.0
species: 284787
type: SpeciesReference

291093
value: -999999.0
type: LocalParameter

289956
fast: false
reversible: false
reactant: 414266
reactant: 414254
product: 414278
name: R_NAD_kinase__mitochondrial
kinetic law: 414315
product: 414290
product: 414303
notes: GENE_ASSOCIATION: ( YEL041W or YJR049C or YPL188W ) PROTEIN_ASSOCIATION: ( Utr2-m ) or ( Utr1-m ) or ( Pos5-m ) SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 2.7.1.23
type: Reaction

298060
value: 999999.0
type: LocalParameter

385923
stoichiometry: 1.0
species: 285204
type: SpeciesReference

293214
value: 0.0
type: LocalParameter

292026
value: 0.0
type: LocalParameter

293625
value: 0.0
type: LocalParameter

379229
stoichiometry: 1.0
species: 286060
type: SpeciesReference

303781
value: 999999.0
type: LocalParameter

283212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxododecanoyl_CoA_C33H52N7O18P3S
type: Species

298337
value: 0.0
type: LocalParameter

299437
value: 0.0
type: LocalParameter

285553
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_octadecadienoate__n_C182__C18H31O2
type: Species

283953
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Choline_C5H14NO
type: Species

351889
stoichiometry: 1.0
species: 285751
type: SpeciesReference

283848
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_But_1_ene_1_2_4_tricarboxylate_C7H5O6
type: Species

344931
stoichiometry: 1.0
species: 283080
type: SpeciesReference

293564
value: 0.0
type: LocalParameter

432210
stoichiometry: 1.0
species: 283626
type: SpeciesReference

297815
value: 0.0
type: LocalParameter

299593
value: 999999.0
type: LocalParameter

361562
stoichiometry: 1.0
species: 284334
type: SpeciesReference

345751
stoichiometry: 1.0
species: 283188
type: SpeciesReference

301409
value: -999999.0
type: LocalParameter

303782
value: 0.0
type: LocalParameter

292027
value: -999999.0
type: LocalParameter

383939
stoichiometry: 6.0
species: 284808
type: SpeciesReference

430879
stoichiometry: 1.0
species: 285979
type: SpeciesReference

404059
stoichiometry: 1.0
species: 285014
type: SpeciesReference

293777
value: 999999.0
type: LocalParameter

298338
value: -999999.0
type: LocalParameter

389065
stoichiometry: 1.0
species: 284757
type: SpeciesReference

292172
value: 0.0
type: LocalParameter

284735
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_GTP_C10H12N5O14P3
type: Species

405363
stoichiometry: 0.01
species: 282893
type: SpeciesReference

349918
stoichiometry: 1.0
species: 285988
type: SpeciesReference

299592
value: 0.0
type: LocalParameter

292807
value: 0.0
type: LocalParameter

297814
value: 999999.0
type: LocalParameter

428712
stoichiometry: 1.0
species: 283584
type: SpeciesReference

384990
stoichiometry: 4.0
species: 283530
type: SpeciesReference

292171
value: 0.0
type: LocalParameter

380414
stoichiometry: 1.0
species: 283416
type: SpeciesReference

435272
stoichiometry: 1.0
species: 286123
type: SpeciesReference

289522
kinetic law: 400023
product: 400010
reactant: 399998
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_bicarbonate_nuclear_transport_via_diffusion
type: Reaction

298482
value: 0.0
type: LocalParameter

298339
value: 999999.0
type: LocalParameter

399822
stoichiometry: 1.0
species: 284757
type: SpeciesReference

293566
value: 0.0
type: LocalParameter

293627
value: 0.0
type: LocalParameter

289520
type: Reaction
product: 399961
reactant: 399937
kinetic law: 399986
fast: false
name: R_HCO3_equilibrium_reaction__nuclear
product: 399973
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Other PROTEIN_CLASS:
reactant: 399949
reversible: true

299435
value: 0.019085
type: LocalParameter

387417
stoichiometry: 1.0
species: 285219
type: SpeciesReference

299591
value: -0.023758
type: LocalParameter

378299
stoichiometry: 1.0
species: 286894
type: SpeciesReference

298483
value: -0.057019
type: LocalParameter

290528
notes: GENE_ASSOCIATION: YHR104W PROTEIN_ASSOCIATION: Gre3 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.21
reactant: 432548
product: 432572
reactant: 432524
reversible: false
kinetic law: 432585
fast: false
reactant: 432536
type: Reaction
product: 432560
name: R_D_sorbitol_reductase

282896
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1_3_beta_D_Glucan_C6H10O5
type: Species

292029
value: 999999.0
type: LocalParameter

293779
value: 0.0
type: LocalParameter

291098
value: 0.0
type: LocalParameter

299434
value: 0.0
type: LocalParameter

418684
stoichiometry: 1.0
species: 284951
type: SpeciesReference

346427
stoichiometry: 1.0
species: 285412
type: SpeciesReference

292174
value: 999999.0
type: LocalParameter

285032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indole_3_acetate_C10H8NO2
type: Species

436530
stoichiometry: 1.0
species: 285751
type: SpeciesReference

297816
value: 0.0
type: LocalParameter

292809
value: 0.0
type: LocalParameter

348433
stoichiometry: 1.0
species: 283521
type: SpeciesReference

288647
kinetic law: 376333
product: 376321
reactant: 376309
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_fecosterol_ester__yeast_specific_exchange
type: Reaction

442001
stoichiometry: 1.0
species: 286369
type: SpeciesReference

298484
value: -999999.0
type: LocalParameter

293210
value: 0.0
type: LocalParameter

384697
stoichiometry: 8.0
species: 285406
type: SpeciesReference

372085
stoichiometry: 1.0
species: 284790
type: SpeciesReference

292852
value: 0.0
type: LocalParameter

299406
value: 0.0
type: LocalParameter

299599
value: 0.0
type: LocalParameter

409592
stoichiometry: 1.0
species: 285399
type: SpeciesReference

380993
stoichiometry: 1.0
species: 283845
type: SpeciesReference

302377
value: 999999.0
type: LocalParameter

435912
stoichiometry: 1.0
species: 283614
type: SpeciesReference

433177
stoichiometry: 1.0
species: 285436
type: SpeciesReference

297961
value: 0.0
type: LocalParameter

357630
stoichiometry: 1.0
species: 284757
type: SpeciesReference

397185
stoichiometry: 1.0
species: 284618
type: SpeciesReference

362964
stoichiometry: 1.0
species: 285883
type: SpeciesReference

349386
stoichiometry: 1.0
species: 284852
type: SpeciesReference

420375
stoichiometry: 1.0
species: 285670
type: SpeciesReference

289988
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.6
product: 415393
product: 415406
reactant: 415357
reactant: 415369
fast: false
type: Reaction
name: R_nucleoside_diphosphatase__UDP_
product: 415381
kinetic law: 415418
reversible: false

285583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_hydroxide_ion_HO
type: Species

287143
product: 345605
notes: GENE_ASSOCIATION: YJR025C PROTEIN_ASSOCIATION: Bna1 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.13.11.6
fast: false
name: R_3_hydroxyanthranilate_3_4_dioxygenase
kinetic law: 345617
reversible: false
reactant: 345581
reactant: 345569
type: Reaction
product: 345593

301571
value: 0.0
type: LocalParameter

374934
stoichiometry: 1.0
species: 283587
type: SpeciesReference

300729
value: 0.0
type: LocalParameter

401649
stoichiometry: 1.0
species: 284757
type: SpeciesReference

297227
value: -999999.0
type: LocalParameter

300616
value: 999999.0
type: LocalParameter

288497
kinetic law: 374523
product: 374511
reactant: 374499
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_Carboxy_3_hydroxy_4_methylpentanoate_exchange
type: Reaction

303751
value: -999999.0
type: LocalParameter

411376
stoichiometry: 1.0
species: 285297
type: SpeciesReference

283440
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Kynurenine_C10H12N2O3
type: Species

283971
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Citrate_C6H5O7
type: Species

299407
value: 0.015001
type: LocalParameter

293526
value: 0.0
type: LocalParameter

393235
stoichiometry: 1.0
species: 284001
type: SpeciesReference

344251
stoichiometry: 1.0
species: 285396
type: SpeciesReference

442897
stoichiometry: 0.03
species: 285529
type: SpeciesReference

297962
value: 999999.0
type: LocalParameter

293110
value: 0.0
type: LocalParameter

395555
stoichiometry: 1.0
species: 285454
type: SpeciesReference

301427
value: 0.0
type: LocalParameter

282890
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_10_Formyltetrahydrofolate_C20H21N7O7
type: Species

435128
stoichiometry: 1.0
species: 284499
type: SpeciesReference

300617
value: 0.0
type: LocalParameter

301570
value: 0.0
type: LocalParameter

384336
stoichiometry: 8.0
species: 284808
type: SpeciesReference

356799
stoichiometry: 1.0
species: 283485
type: SpeciesReference

302258
value: 999999.0
type: LocalParameter

292850
value: 999999.0
type: LocalParameter

405218
stoichiometry: 1.0
species: 283920
type: SpeciesReference

303754
value: 0.0
type: LocalParameter

359819
stoichiometry: 1.0
species: 283605
type: SpeciesReference

383709
stoichiometry: 1.0
species: 285433
type: SpeciesReference

443524
stoichiometry: 6.0E-5
species: 285670
type: SpeciesReference

288494
kinetic law: 374487
product: 374475
reactant: 374463
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_phenylethanol_exchange
type: Reaction

302375
value: 0.0
type: LocalParameter

283554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_O_Acetyl_L_homoserine_C6H11NO4
type: Species

374330
stoichiometry: 1.0
species: 286567
type: SpeciesReference

421658
stoichiometry: 1.0
species: 284541
type: SpeciesReference

386191
stoichiometry: 1.0
species: 285487
type: SpeciesReference

428942
stoichiometry: 1.0
species: 285760
type: SpeciesReference

301426
value: 0.0
type: LocalParameter

371419
stoichiometry: 1.0
species: 284787
type: SpeciesReference

396410
stoichiometry: 1.0
species: 285436
type: SpeciesReference

435767
stoichiometry: 1.0
species: 283473
type: SpeciesReference

384264
stoichiometry: 8.0
species: 284025
type: SpeciesReference

369677
stoichiometry: 1.0
species: 285604
type: SpeciesReference

303753
value: 999999.0
type: LocalParameter

299409
value: 0.0
type: LocalParameter

302376
value: -999999.0
type: LocalParameter

293419
value: 0.0
type: LocalParameter

293524
value: 0.0
type: LocalParameter

290510
kinetic law: 431907
product: 431895
reactant: 431883
notes: GENE_ASSOCIATION: YOR095C PROTEIN_ASSOCIATION: Rki1 SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 5.3.1.6
fast: false
reversible: true
name: R_ribose_5_phosphate_isomerase
type: Reaction

297225
value: -0.080183
type: LocalParameter

443681
stoichiometry: 0.1914
species: 286204
type: SpeciesReference

357233
stoichiometry: 1.0
species: 283716
type: SpeciesReference

297960
value: -0.041576
type: LocalParameter

285580
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

301425
value: 0.0
type: LocalParameter

289251
type: Reaction
notes: GENE_ASSOCIATION: YOL059W PROTEIN_ASSOCIATION: Gpd2.1-m SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS: 1.1.1.8
product: 391400
name: R_glycerol_3_phosphate_dehydrogenase__NAD___mitochondrial
fast: false
reactant: 391352
reactant: 391364
reactant: 391376
kinetic law: 391412
reversible: false
product: 391388

426062
stoichiometry: 1.0
species: 283992
type: SpeciesReference

410712
stoichiometry: 1.0
species: 285285
type: SpeciesReference

287146
kinetic law: 345665
product: 345653
product: 345641
reactant: 345629
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
fast: false
reversible: false
name: R_3_Hexaprenyl_4_hydroxy_5_methoxybenzoate_decarboxylase__mitochondrial
type: Reaction

362276
stoichiometry: 1.0
species: 284022
type: SpeciesReference

297222
value: 0.0
type: LocalParameter

300611
value: 0.0
type: LocalParameter

292279
value: 0.0
type: LocalParameter

302256
value: 0.0
type: LocalParameter

285586
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_hydroxide_ion_HO
type: Species

403889
stoichiometry: 1.0
species: 285011
type: SpeciesReference

292856
value: 0.0
type: LocalParameter

292384
value: 0.0
type: LocalParameter

297812
value: 0.0
type: LocalParameter

287149
notes: GENE_ASSOCIATION: YER175C PROTEIN_ASSOCIATION: Tmt1 SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS: 2.1.1.145
name: R_3_Isopropylmalate_3_methyltransferase
product: 345702
reactant: 345678
fast: false
kinetic law: 345727
product: 345715
type: Reaction
reversible: false
reactant: 345690

289984
fast: false
reversible: false
name: R_nucleoside_diphosphatase__GDP___Golgi
product: 415261
product: 415249
notes: GENE_ASSOCIATION: YEL042W PROTEIN_ASSOCIATION: Gda1-g SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.6
product: 415237
reactant: 415225
type: Reaction
reactant: 415213
kinetic law: 415273

303757
value: 0.0
type: LocalParameter

298480
value: 0.0
type: LocalParameter

436227
stoichiometry: 1.0
species: 286234
type: SpeciesReference

427742
stoichiometry: 1.0
species: 285859
type: SpeciesReference

394479
stoichiometry: 1.0
species: 284589
type: SpeciesReference

428520
stoichiometry: 1.0
species: 284796
type: SpeciesReference

302144
value: 0.0
type: LocalParameter

293522
value: 999999.0
type: LocalParameter

297223
value: 0.0
type: LocalParameter

300612
value: 0.0
type: LocalParameter

302257
value: 0.0
type: LocalParameter

385413
stoichiometry: 1.0
species: 284115
type: SpeciesReference

284817
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Bicarbonate_CHO3
type: Species

292857
value: 0.0
type: LocalParameter

388969
stoichiometry: 0.27
species: 285577
type: SpeciesReference

283557
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_E_3_carboxyl_2_pentenedioate_5_methyl_ester_C7H6O6
type: Species

362844
stoichiometry: 1.0
species: 283908
type: SpeciesReference

299595
value: 0.0
type: LocalParameter

356583
stoichiometry: 1.0
species: 284747
type: SpeciesReference

303756
value: -0.482664
type: LocalParameter

426376
stoichiometry: 1.0
species: 283800
type: SpeciesReference

302379
value: 0.0
type: LocalParameter

300613
value: 0.0
type: LocalParameter

302141
value: 0.0
type: LocalParameter

302254
value: 0.019085
type: LocalParameter

292382
value: 999999.0
type: LocalParameter

284921
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hydroxymethylbilane_C40H38N4O17
type: Species

292277
value: 0.0
type: LocalParameter

365913
stoichiometry: 1.0
species: 284025
type: SpeciesReference

292854
value: 0.04626
type: LocalParameter

352526
stoichiometry: 1.0
species: 283635
type: SpeciesReference

378262
stoichiometry: 1.0
species: 286891
type: SpeciesReference

299596
value: 0.0
type: LocalParameter

427016
stoichiometry: 1.0
species: 285853
type: SpeciesReference

421004
stoichiometry: 1.0
species: 283734
type: SpeciesReference

289986
product: 415309
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.6
fast: false
reversible: false
reactant: 415285
type: Reaction
product: 415333
product: 415321
kinetic law: 415345
name: R_nucleoside_diphosphatase__dGDP_
reactant: 415297

297810
value: 0.0
type: LocalParameter

348964
stoichiometry: 1.0
species: 283533
type: SpeciesReference

288491
kinetic law: 374451
product: 374439
reactant: 374427
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_methylpropanal_exchange
type: Reaction

297221
value: 999999.0
type: LocalParameter

302142
value: 0.0
type: LocalParameter

436506
stoichiometry: 1.0
species: 284757
type: SpeciesReference

282893
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

421875
stoichiometry: 1.0
species: 284757
type: SpeciesReference

295052
value: 0.001267
type: LocalParameter

299598
value: -0.023758
type: LocalParameter

440538
stoichiometry: 2.0
species: 284787
type: SpeciesReference

292380
value: 0.0
type: LocalParameter

400856
stoichiometry: 1.0
species: 285412
type: SpeciesReference

414896
stoichiometry: 1.0
species: 285469
type: SpeciesReference

366682
stoichiometry: 1.0
species: 285466
type: SpeciesReference

288638
kinetic law: 376224
product: 376212
reactant: 376200
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Ethanol_exchange
type: Reaction

303758
value: -999999.0
type: LocalParameter

353369
stoichiometry: 1.0
species: 283659
type: SpeciesReference

296722
value: -0.047516
type: LocalParameter

417944
stoichiometry: 1.0
species: 285038
type: SpeciesReference

298371
value: -999999.0
type: LocalParameter

363132
stoichiometry: 1.0
species: 283920
type: SpeciesReference

298788
value: 0.0
type: LocalParameter

297969
value: 999999.0
type: LocalParameter

400700
stoichiometry: 1.0
species: 284882
type: SpeciesReference

293117
value: 0.0
type: LocalParameter

441082
stoichiometry: 1.0
species: 284790
type: SpeciesReference

284814
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_2_Hydroxybutane_1_2_4_tricarboxylate_C7H7O7
type: Species

292388
value: -0.041576
type: LocalParameter

284927
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

292275
value: 0.0
type: LocalParameter

290660
kinetic law: 436857
product: 436845
product: 436833
reactant: 436821
notes: GENE_ASSOCIATION: ( YCL064C or YKL218C ) PROTEIN_ASSOCIATION: ( Cha1 ) or ( Sry1 ) SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.3.1.19
fast: false
reversible: false
name: R_L_threonine_deaminase
type: Reaction

289257
notes: GENE_ASSOCIATION: ( YER062C or YIL053W ) PROTEIN_ASSOCIATION: ( Hor2 ) or ( Rhr2 ) SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS:
reversible: false
name: R_glycerol_3_phosphatase
type: Reaction
product: 391557
reactant: 391533
fast: false
product: 391545
reactant: 391521
kinetic law: 391569

298025
value: 0.0
type: LocalParameter

384035
stoichiometry: 7.0
species: 285406
type: SpeciesReference

298370
value: 0.0
type: LocalParameter

396712
stoichiometry: 1.0
species: 284675
type: SpeciesReference

302149
value: 0.0
type: LocalParameter

348892
stoichiometry: 1.0
species: 284757
type: SpeciesReference

352826
stoichiometry: 1.0
species: 283641
type: SpeciesReference

403732
stoichiometry: 1.0
species: 286312
type: SpeciesReference

295055
value: 0.0
type: LocalParameter

288986
fast: false
type: Reaction
kinetic law: 380582
reversible: false
reactant: 380510
product: 380570
product: 380558
name: R_fatty_acid_peroxisomal_transport_via_ABC_system
reactant: 380498
product: 380534
reactant: 380522
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
product: 380546

287257
kinetic law: 347700
product: 347688
product: 347676
reactant: 347664
notes: GENE_ASSOCIATION: YPL028W PROTEIN_ASSOCIATION: Erg10 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.9
fast: false
reversible: false
name: R_acetyl_CoA_C_acetyltransferase
type: Reaction

297395
value: 999999.0
type: LocalParameter

298024
value: 0.0
type: LocalParameter

289980
product: 415090
kinetic law: 415127
reversible: false
fast: false
name: R_nucleoside_diphosphatase__ADP_
reactant: 415065
reactant: 415077
type: Reaction
product: 415102
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.6
product: 415115

415827
stoichiometry: 1.0
species: 284142
type: SpeciesReference

432427
stoichiometry: 1.0
species: 285409
type: SpeciesReference

302370
value: 999999.0
type: LocalParameter

302253
value: 0.0
type: LocalParameter

293413
value: 999999.0
type: LocalParameter

300721
value: 0.0
type: LocalParameter

297114
value: -0.06969
type: LocalParameter

302148
value: 0.0
type: LocalParameter

430151
stoichiometry: 1.0
species: 284796
type: SpeciesReference

287809
product: 359554
fast: false
product: 359578
type: Reaction
product: 359566
reversible: false
reactant: 359530
name: R_ATP_diphosphohydrolase
reactant: 359542
kinetic law: 359590
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.5

297110
value: 999999.0
type: LocalParameter

407140
stoichiometry: 1.0
species: 286321
type: SpeciesReference

293329
value: 0.0
type: LocalParameter

295056
value: 0.0
type: LocalParameter

296724
value: 0.0
type: LocalParameter

298786
value: 0.0
type: LocalParameter

293115
value: 0.0
type: LocalParameter

426220
stoichiometry: 1.0
species: 283602
type: SpeciesReference

427125
stoichiometry: 0.01
species: 285862
type: SpeciesReference

298022
value: 0.0
type: LocalParameter

400264
stoichiometry: 1.0
species: 285493
type: SpeciesReference

297967
value: 0.0
type: LocalParameter

302250
value: 0.0
type: LocalParameter

283449
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_pai__Methyl_L_histidine_C7H11N3O2
type: Species

293410
value: 0.0
type: LocalParameter

292273
value: 999999.0
type: LocalParameter

289259
reactant: 391581
type: Reaction
name: R_L_glutamate_5_semialdehyde_dehydratase__reversible
product: 391617
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS:
kinetic law: 391629
product: 391593
product: 391605
fast: false
reversible: true

390263
stoichiometry: 1.0
species: 284790
type: SpeciesReference

292386
value: 0.0
type: LocalParameter

297111
value: 0.0
type: LocalParameter

302145
value: 0.0
type: LocalParameter

300722
value: 0.0
type: LocalParameter

442727
stoichiometry: 0.27
species: 285577
type: SpeciesReference

290662
kinetic law: 436906
product: 436893
product: 436881
reactant: 436869
notes: GENE_ASSOCIATION: YER086W PROTEIN_ASSOCIATION: Ilv1-m SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.3.1.19
fast: false
reversible: false
name: R_L_threonine_deaminase__mitochondrial
type: Reaction

294909
value: 0.0
type: LocalParameter

298785
value: 0.0
type: LocalParameter

381670
stoichiometry: 1.0
species: 285577
type: SpeciesReference

298021
value: 999999.0
type: LocalParameter

297968
value: 0.0
type: LocalParameter

358462
stoichiometry: 1.0
species: 283800
type: SpeciesReference

379640
stoichiometry: 1.0
species: 287005
type: SpeciesReference

293411
value: 0.0
type: LocalParameter

367045
stoichiometry: 1.0
species: 284732
type: SpeciesReference

289982
product: 415163
reactant: 415151
fast: false
product: 415188
kinetic law: 415200
reactant: 415139
type: Reaction
reversible: false
name: R_nucleoside_diphosphatase__GDP_
product: 415176
notes: GENE_ASSOCIATION: YER005W PROTEIN_ASSOCIATION: Ynd1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.6

393815
stoichiometry: 1.0
species: 284618
type: SpeciesReference

284811
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Hydroxybutane_1_2_4_tricarboxylate_C7H7O7
type: Species

297393
value: -999999.0
type: LocalParameter

285694
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_all_trans_Pentaprenyl_diphosphate_C25H41O7P2
type: Species

284924
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

439603
stoichiometry: 1.0
species: 286417
type: SpeciesReference

288382
product: 372243
reactant: 372207
type: Reaction
product: 372231
fast: false
reactant: 372219
kinetic law: 372255
reversible: true
name: R_D_lactate_transport__mitochondrial
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:

302146
value: 999999.0
type: LocalParameter

297112
value: 0.0
type: LocalParameter

291480
value: 999999.0
type: LocalParameter

351185
stoichiometry: 1.0
species: 283602
type: SpeciesReference

302251
value: 999999.0
type: LocalParameter

288983
kinetic law: 380486
product: 380474
reactant: 380462
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport
type: Reaction

414788
stoichiometry: 1.0
species: 285402
type: SpeciesReference

292270
value: 0.0
type: LocalParameter

297399
value: 0.0
type: LocalParameter

415041
stoichiometry: 1.0
species: 285384
type: SpeciesReference

410866
stoichiometry: 0.01
species: 285919
type: SpeciesReference

420484
stoichiometry: 1.0
species: 283113
type: SpeciesReference

293113
value: 999999.0
type: LocalParameter

384794
stoichiometry: 3.0
species: 284025
type: SpeciesReference

288388
kinetic law: 372328
product: 372316
reactant: 372304
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_erythro_4_hydroxyglutamate_peroxisomal_transport_via_diffusion
type: Reaction

424908
stoichiometry: 1.0
species: 284790
type: SpeciesReference

297965
value: 0.0
type: LocalParameter

290664
reversible: false
kinetic law: 436967
name: R_threonine_synthase
type: Reaction
notes: GENE_ASSOCIATION: YCR053W PROTEIN_ASSOCIATION: Thr4 SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.2.3.1
product: 436942
reactant: 436930
product: 436954
reactant: 436918
fast: false

300724
value: -0.271631
type: LocalParameter

283443
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N1_Acetylspermidine_C9H23N3O
type: Species

297117
value: 999999.0
type: LocalParameter

302373
value: 0.164049
type: LocalParameter

293529
value: -999999.0
type: LocalParameter

410651
stoichiometry: 1.0
species: 283395
type: SpeciesReference

298029
value: 0.0
type: LocalParameter

300619
value: 0.0
type: LocalParameter

292271
value: -999999.0
type: LocalParameter

295059
value: 999999.0
type: LocalParameter

289253
type: Reaction
product: 391461
reactant: 391424
name: R_glycerol_3_phosphate_dehydrogenase__FAD___mitochondrial
kinetic law: 391473
notes: GENE_ASSOCIATION: YIL155C PROTEIN_ASSOCIATION: Gut2-m SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS: 1.1.99.5
reversible: false
fast: false
product: 391449
reactant: 391437

293328
value: -0.035043
type: LocalParameter

298783
value: 999999.0
type: LocalParameter

426667
stoichiometry: 1.0
species: 285838
type: SpeciesReference

285691
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Pectin_C6H7O6
type: Species

393126
stoichiometry: 1.0
species: 284553
type: SpeciesReference

349494
stoichiometry: 1.0
species: 284754
type: SpeciesReference

284502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucose_1_phosphate_C6H11O9P
type: Species

300725
value: -999999.0
type: LocalParameter

297118
value: 0.0
type: LocalParameter

291482
value: 0.0
type: LocalParameter

293417
value: 0.0
type: LocalParameter

294903
value: 999999.0
type: LocalParameter

429497
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298782
value: -999999.0
type: LocalParameter

345629
stoichiometry: 1.0
species: 283170
type: SpeciesReference

301422
value: 0.0
type: LocalParameter

426172
stoichiometry: 1.0
species: 285751
type: SpeciesReference

297397
value: 0.0
type: LocalParameter

350087
stoichiometry: 1.0
species: 283497
type: SpeciesReference

293325
value: 0.0
type: LocalParameter

293111
value: -999999.0
type: LocalParameter

294906
value: 0.0
type: LocalParameter

296720
value: 0.0
type: LocalParameter

386082
stoichiometry: 1.0
species: 284013
type: SpeciesReference

290666
reactant: 436991
reactant: 437003
type: Reaction
product: 437015
product: 437027
kinetic law: 437051
product: 437039
name: R_Threonyl_tRNA_synthetase
reactant: 436979
reversible: false
notes: GENE_ASSOCIATION: YIL078W PROTEIN_ASSOCIATION: Ths1 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.3
fast: false

288385
kinetic law: 372292
product: 372280
reactant: 372268
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_erythro_4_hydroxyglutamate_mitochondrial_transport_via_diffusion
type: Reaction

297115
value: 0.0
type: LocalParameter

347091
stoichiometry: 1.0
species: 284747
type: SpeciesReference

300726
value: 999999.0
type: LocalParameter

288980
product: 380414
reactant: 380390
reversible: true
type: Reaction
name: R_fatty_acyl_ACP_hydrolase
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 3.1.2.14
reactant: 380402
fast: false
product: 380426
kinetic law: 380450
product: 380438

298027
value: 999999.0
type: LocalParameter

297396
value: 0.0
type: LocalParameter

301421
value: 999999.0
type: LocalParameter

298781
value: 0.0
type: LocalParameter

289255
kinetic law: 391509
product: 391497
reactant: 391485
notes: GENE_ASSOCIATION: YCR098C PROTEIN_ASSOCIATION: Git1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_glycero_3_phospho_1_inositol_transport__extracellular_to_cytosol_
type: Reaction

297964
value: 0.0
type: LocalParameter

375127
stoichiometry: 1.0
species: 286633
type: SpeciesReference

292389
value: 0.0
type: LocalParameter

291484
value: 0.0
type: LocalParameter

283551
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_N_Acetyl_L_glutamate_C7H9NO5
type: Species

293528
value: 0.0
type: LocalParameter

293415
value: 0.0
type: LocalParameter

302372
value: 0.0
type: LocalParameter

357955
stoichiometry: 1.0
species: 283836
type: SpeciesReference

395483
stoichiometry: 1.0
species: 284520
type: SpeciesReference

366526
stoichiometry: 1.0
species: 283074
type: SpeciesReference

435876
stoichiometry: 1.0
species: 286141
type: SpeciesReference

283446
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N1_Acetylspermine_C12H31N4O
type: Species

298026
value: 0.0
type: LocalParameter

287254
kinetic law: 347651
type: Reaction
name: R_4_aminobutyrate_reversible_transport_in_via_proton_symport
reactant: 347615
fast: false
reversible: true
notes: GENE_ASSOCIATION: ( YOR348C or YDL210W ) PROTEIN_ASSOCIATION: ( Put4 ) or ( Uga4 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 347627
reactant: 347602
product: 347639

298780
value: 0.0
type: LocalParameter

287260
kinetic law: 347748
product: 347736
product: 347724
reactant: 347712
notes: GENE_ASSOCIATION: YPL028W PROTEIN_ASSOCIATION: Erg10-m SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.9
fast: false
reversible: false
name: R_acetyl_CoA_C_acetyltransferase__mitochondrial
type: Reaction

292056
value: 999999.0
type: LocalParameter

293869
value: 0.0
type: LocalParameter

292169
value: 0.04626
type: LocalParameter

298367
value: 0.0
type: LocalParameter

383188
stoichiometry: 1.0
species: 283845
type: SpeciesReference

356256
stoichiometry: 1.0
species: 283713
type: SpeciesReference

355061
stoichiometry: 1.0
species: 285436
type: SpeciesReference

284708
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Guanosine_C10H13N5O5
type: Species

287812
type: Reaction
reactant: 359615
product: 359639
fast: false
name: R_ATP_maintenance_requirement
reactant: 359602
reversible: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS:
kinetic law: 359663
product: 359651
product: 359627

293630
value: 0.0
type: LocalParameter

394361
stoichiometry: 1.0
species: 284681
type: SpeciesReference

302034
value: 0.0
type: LocalParameter

291475
value: 0.0
type: LocalParameter

397029
stoichiometry: 1.0
species: 284663
type: SpeciesReference

290668
fast: false
reversible: false
notes: GENE_ASSOCIATION: YKL194C PROTEIN_ASSOCIATION: Mst1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.3
kinetic law: 437137
type: Reaction
product: 437112
reactant: 437063
reactant: 437075
product: 437125
reactant: 437087
product: 437100
name: R_threonyl_tRNA_synthetase__mitochondrial

298368
value: 0.0
type: LocalParameter

294900
value: 0.0
type: LocalParameter

350364
stoichiometry: 1.0
species: 283497
type: SpeciesReference

427899
stoichiometry: 1.0
species: 285916
type: SpeciesReference

363350
stoichiometry: 1.0
species: 283908
type: SpeciesReference

353477
stoichiometry: 1.0
species: 284675
type: SpeciesReference

293335
value: 0.0
type: LocalParameter

296718
value: 999999.0
type: LocalParameter

292054
value: -999999.0
type: LocalParameter

292167
value: 0.0
type: LocalParameter

293972
value: 0.0
type: LocalParameter

298478
value: 0.0
type: LocalParameter

298365
value: 999999.0
type: LocalParameter

434536
stoichiometry: 1.0
species: 284772
type: SpeciesReference

302033
value: -0.011879
type: LocalParameter

393972
stoichiometry: 1.0
species: 286171
type: SpeciesReference

348241
stoichiometry: 1.0
species: 283521
type: SpeciesReference

401073
stoichiometry: 1.0
species: 283713
type: SpeciesReference

396932
stoichiometry: 1.0
species: 284657
type: SpeciesReference

298364
value: -999999.0
type: LocalParameter

288379
type: Reaction
product: 372170
reactant: 372158
reversible: true
product: 372182
reactant: 372146
kinetic law: 372194
name: R_D_lactatepyruvate_antiport__mitochondrial
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:

296719
value: 0.0
type: LocalParameter

288521
kinetic law: 374814
product: 374802
reactant: 374790
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Arabinitol_exchange
type: Reaction

291477
value: 0.0
type: LocalParameter

287263
kinetic law: 347809
fast: false
product: 347785
type: Reaction
reactant: 347773
product: 347797
name: R_acetyl_CoA_C_acetyltransferase__octanoyl_CoA___peroxisomal
notes: GENE_ASSOCIATION: YIL160C PROTEIN_ASSOCIATION: Pot1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 2.3.1.16
reversible: false
reactant: 347761

293866
value: 0.0
type: LocalParameter

297119
value: 0.0
type: LocalParameter

293749
value: 0.0
type: LocalParameter

298479
value: 999999.0
type: LocalParameter

302032
value: 0.0
type: LocalParameter

356112
stoichiometry: 1.0
species: 283713
type: SpeciesReference

381778
stoichiometry: 1.0
species: 285544
type: SpeciesReference

293333
value: 0.0
type: LocalParameter

346452
stoichiometry: 1.0
species: 283308
type: SpeciesReference

405544
stoichiometry: 1.0
species: 283122
type: SpeciesReference

293635
value: 0.0
type: LocalParameter

383819
stoichiometry: 5.0
species: 284754
type: SpeciesReference

406078
stoichiometry: 1.0
species: 283725
type: SpeciesReference

346307
stoichiometry: 1.0
species: 283293
type: SpeciesReference

291478
value: -999999.0
type: LocalParameter

443802
stoichiometry: 59.305
species: 285751
type: SpeciesReference

412029
stoichiometry: 0.01
species: 282893
type: SpeciesReference

288527
kinetic law: 374886
product: 374874
reactant: 374862
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Acetaldehyde_exchange
type: Reaction

298362
value: 0.0
type: LocalParameter

289642
reactant: 403720
fast: false
reactant: 403708
type: Reaction
notes: GENE_ASSOCIATION: YBL076C PROTEIN_ASSOCIATION: Ils1 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.5
reactant: 403732
kinetic law: 403781
product: 403757
product: 403769
name: R_Isoleucyl_tRNA_synthetase
product: 403745
reversible: false

384577
stoichiometry: 7.0
species: 285499
type: SpeciesReference

289640
fast: false
product: 403671
reactant: 403647
notes: GENE_ASSOCIATION: YHR208W PROTEIN_ASSOCIATION: Bat1-m SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 2.6.1.42
reversible: true
type: Reaction
product: 403683
name: R_isoleucine_transaminase__mitochondrial
reactant: 403659
kinetic law: 403696

293747
value: 999999.0
type: LocalParameter

369521
stoichiometry: 1.0
species: 284202
type: SpeciesReference

289249
product: 391327
reversible: false
fast: false
reactant: 391303
notes: GENE_ASSOCIATION: YDL022W PROTEIN_ASSOCIATION: Gpd1 SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS: 1.1.1.8
name: R_glycerol_3_phosphate_dehydrogenase__NAD_
product: 391315
reactant: 391291
kinetic law: 391340
type: Reaction
reactant: 391279

293420
value: 0.0
type: LocalParameter

359978
stoichiometry: 3.0
species: 284787
type: SpeciesReference

422153
stoichiometry: 1.0
species: 284796
type: SpeciesReference

351745
stoichiometry: 1.0
species: 284493
type: SpeciesReference

292053
value: 0.0
type: LocalParameter

302030
value: 0.0
type: LocalParameter

353901
stoichiometry: 1.0
species: 285436
type: SpeciesReference

296714
value: -0.023758
type: LocalParameter

375561
stoichiometry: 1.0
species: 286669
type: SpeciesReference

298032
value: -0.007721
type: LocalParameter

392728
stoichiometry: 1.0
species: 284442
type: SpeciesReference

298363
value: -0.059395
type: LocalParameter

293331
value: 999999.0
type: LocalParameter

287815
name: R_ATP_phosphoribosyltransferase
type: Reaction
kinetic law: 359723
product: 359699
fast: false
reactant: 359687
product: 359711
notes: GENE_ASSOCIATION: YER055C PROTEIN_ASSOCIATION: His1 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 2.4.2.17
reactant: 359675
reversible: false

289536
name: R_hydroxyethylthiazole_kinase
reactant: 400410
product: 400447
product: 400434
reactant: 400398
reversible: false
fast: false
type: Reaction
product: 400422
notes: GENE_ASSOCIATION: YPL214C PROTEIN_ASSOCIATION: Thi6 SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.7.1.50
kinetic law: 400459

399901
stoichiometry: 1.0
species: 284796
type: SpeciesReference

293633
value: 999999.0
type: LocalParameter

430999
stoichiometry: 1.0
species: 284088
type: SpeciesReference

422261
stoichiometry: 1.0
species: 284618
type: SpeciesReference

298789
value: 0.0
type: LocalParameter

293108
value: 0.0
type: LocalParameter

380534
stoichiometry: 1.0
species: 283617
type: SpeciesReference

394166
stoichiometry: 1.0
species: 284103
type: SpeciesReference

298360
value: 0.0
type: LocalParameter

287818
notes: GENE_ASSOCIATION: ( ( YCR024C-A and YEL017C-A and YGL008C ) or ( YCR024C-A and YEL017C-A and YPL036W ) ) PROTEIN_ASSOCIATION: ( Pma1 ) or ( Pma2 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: 3.6.3.6
fast: false
product: 359771
product: 359759
reactant: 359735
name: R_ATPase__cytosolic
product: 359783
type: Reaction
reactant: 359747
kinetic law: 359795
reversible: false

289644
kinetic law: 403865
fast: false
name: R_isoleucyl_tRNA_synthetase__mitochondrial
reversible: false
notes: GENE_ASSOCIATION: YPL040C PROTEIN_ASSOCIATION: Ism1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.5
product: 403853
type: Reaction
product: 403829
reactant: 403805
product: 403841
reactant: 403793
reactant: 403817

357738
stoichiometry: 1.0
species: 283800
type: SpeciesReference

300730
value: 0.0
type: LocalParameter

283332
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_Methyl_2_oxopentanoate_C6H9O3
type: Species

283227
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_3_Hexaprenyl_4_hydroxybenzoate_C37H53O3
type: Species

292051
value: 0.0
type: LocalParameter

285697
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_all_trans_Pentaprenyl_diphosphate_C25H41O7P2
type: Species

283968
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Citrate_C6H5O7
type: Species

288524
kinetic law: 374850
product: 374838
reactant: 374826
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Acetate_exchange
type: Reaction

296716
value: 0.0
type: LocalParameter

415261
stoichiometry: 1.0
species: 285757
type: SpeciesReference

285047
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Indole_3_ethanol_C10H11NO
type: Species

288989
kinetic law: 380618
product: 380606
reactant: 380594
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport
type: Reaction

298030
value: 0.0
type: LocalParameter

297959
value: 0.0
type: LocalParameter

380002
stoichiometry: 1.0
species: 287035
type: SpeciesReference

289538
name: R_hexokinase__D_glucoseATP_
product: 400507
notes: GENE_ASSOCIATION: ( YFR053C or YGL253W or YCL040W ) PROTEIN_ASSOCIATION: ( Hxk1 ) or ( Hxk2 ) or ( Glk1 ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.1
fast: false
reactant: 400483
reactant: 400471
reversible: false
product: 400519
type: Reaction
product: 400495
kinetic law: 400531

298471
value: 0.0
type: LocalParameter

440685
stoichiometry: 1.0
species: 283839
type: SpeciesReference

364959
stoichiometry: 1.0
species: 285646
type: SpeciesReference

289646
reversible: true
reactant: 403877
reactant: 403889
product: 403913
fast: false
type: Reaction
kinetic law: 403925
notes: GENE_ASSOCIATION: ( YBR069C or YKR039W or YCL025C or YBR068C or YDR046C ) PROTEIN_ASSOCIATION: ( Tat1 ) or ( Gap1 ) or ( Agp1 ) or ( Bap2 ) or ( Bap3 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
name: R_L_isoleucine_reversible_transport_via_proton_symport
product: 403901

380112
stoichiometry: 1.0
species: 287044
type: SpeciesReference

290516
product: 432150
reactant: 432113
fast: false
reactant: 432137
reversible: false
notes: GENE_ASSOCIATION: YJR010W PROTEIN_ASSOCIATION: Met3 SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 2.7.7.4
kinetic law: 432174
name: R_sulfate_adenylyltransferase
reactant: 432125
type: Reaction
product: 432162

371638
stoichiometry: 1.0
species: 283602
type: SpeciesReference

292160
value: 0.00711
type: LocalParameter

348518
stoichiometry: 1.0
species: 284544
type: SpeciesReference

387405
stoichiometry: 1.0
species: 284828
type: SpeciesReference

421222
stoichiometry: 1.0
species: 284787
type: SpeciesReference

293744
value: 0.0
type: LocalParameter

283335
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Methyl_5__2_phosphoethyl__thiazole_C6H8NO4PS
type: Species

300620
value: 0.0
type: LocalParameter

293639
value: 0.0
type: LocalParameter

388104
stoichiometry: 3.0
species: 284766
type: SpeciesReference

298472
value: 999999.0
type: LocalParameter

384685
stoichiometry: 8.0
species: 284778
type: SpeciesReference

289532
product: 400288
fast: false
kinetic law: 400312
product: 400300
reactant: 400252
reactant: 400240
product: 400276
name: R_Heme_O_monooxygenase__mitochondrial
reversible: false
notes: GENE_ASSOCIATION: ( YDR376W and YER141W and YPL252C ) PROTEIN_ASSOCIATION: ( Arh1-m and Cox15-m and Yah1-m ) SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS:
reactant: 400264
type: Reaction

372097
stoichiometry: 1.0
species: 285110
type: SpeciesReference

348133
stoichiometry: 2.0
species: 283512
type: SpeciesReference

375670
stoichiometry: 1.0
species: 286678
type: SpeciesReference

297804
value: 0.0
type: LocalParameter

288635
kinetic law: 376188
product: 376176
reactant: 376164
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Ethanolamine_exchange
type: Reaction

349822
stoichiometry: 1.0
species: 283542
type: SpeciesReference

283548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_Acetyl_D_glucosamine_6_phosphate_C8H14NO9P
type: Species

292162
value: 0.0
type: LocalParameter

293743
value: 0.0
type: LocalParameter

433395
stoichiometry: 1.0
species: 286045
type: SpeciesReference

344106
stoichiometry: 1.0
species: 282984
type: SpeciesReference

399835
stoichiometry: 1.0
species: 284787
type: SpeciesReference

283221
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxohexacosyl_CoA_C47H80N7O18P3S
type: Species

293860
value: 999999.0
type: LocalParameter

442014
stoichiometry: 1.0
species: 286501
type: SpeciesReference

289648
reversible: false
type: Reaction
fast: false
product: 403974
product: 403961
reactant: 403949
notes: GENE_ASSOCIATION: YJR001W PROTEIN_ASSOCIATION: Avt1-v SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
kinetic law: 403986
name: R_L_isoleucine_transport_in_via_proton_antiport__vacuolar_
reactant: 403937

290518
product: 432222
name: R_S_adenosyl_methionine_delta_24_sterol_c_methyltransferase
product: 432210
kinetic law: 432246
fast: false
reactant: 432198
reversible: false
notes: GENE_ASSOCIATION: YML008C PROTEIN_ASSOCIATION: Erg6 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 2.1.1.41
type: Reaction
product: 432234
reactant: 432186

413550
stoichiometry: 1.0
species: 285357
type: SpeciesReference

361598
stoichiometry: 2.0
species: 284757
type: SpeciesReference

292859
value: 999999.0
type: LocalParameter

348446
stoichiometry: 1.0
species: 283527
type: SpeciesReference

301578
value: 0.708389
type: LocalParameter

297803
value: 0.0
type: LocalParameter

435344
stoichiometry: 1.0
species: 284787
type: SpeciesReference

285044
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Indole_3_ethanol_C10H11NO
type: Species

283812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Aspartate_C4H6NO4
type: Species

358318
stoichiometry: 1.0
species: 285751
type: SpeciesReference

283965
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Citrate_C6H5O7
type: Species

285589
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Oxo_3_hydroxy_4_phosphobutanoate_C4H4O8P
type: Species

373763
stoichiometry: 0.03
species: 285532
type: SpeciesReference

293637
value: 0.0
type: LocalParameter

351853
stoichiometry: 1.0
species: 284130
type: SpeciesReference

282885
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

300622
value: 999999.0
type: LocalParameter

283224
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Hexaprenyl_4_hydroxybenzoate_C37H53O3
type: Species

298470
value: 0.0
type: LocalParameter

371310
stoichiometry: 1.0
species: 284787
type: SpeciesReference

435284
stoichiometry: 1.0
species: 284490
type: SpeciesReference

383927
stoichiometry: 8.0
species: 283530
type: SpeciesReference

380426
stoichiometry: 1.0
species: 284787
type: SpeciesReference

289534
fast: false
name: R_Heme_O_synthase__mitochondrial
kinetic law: 400385
reactant: 400336
reversible: false
product: 400373
type: Reaction
product: 400361
reactant: 400349
notes: GENE_ASSOCIATION: YPL172C PROTEIN_ASSOCIATION: Cox10-m SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS:
reactant: 400324

301579
value: 0.0
type: LocalParameter

428724
stoichiometry: 1.0
species: 285967
type: SpeciesReference

297802
value: 0.0
type: LocalParameter

425544
stoichiometry: 1.0
species: 285973
type: SpeciesReference

384480
stoichiometry: 8.0
species: 284754
type: SpeciesReference

414303
stoichiometry: 1.0
species: 285427
type: SpeciesReference

383600
stoichiometry: 6.0
species: 284778
type: SpeciesReference

430843
stoichiometry: 1.0
species: 284790
type: SpeciesReference

293979
value: 999999.0
type: LocalParameter

389053
stoichiometry: 0.01
species: 284436
type: SpeciesReference

293741
value: 2.02E-4
type: LocalParameter

299400
value: 0.0
type: LocalParameter

429389
stoichiometry: 1.0
species: 283830
type: SpeciesReference

405436
stoichiometry: 1.0
species: 285083
type: SpeciesReference

300621
value: 0.0
type: LocalParameter

288632
kinetic law: 376152
product: 376140
reactant: 376128
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_ergosterol_ester__yeast_specific_exchange
type: Reaction

357089
stoichiometry: 1.0
species: 285796
type: SpeciesReference

283818
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Aspartate_4_semialdehyde_C4H7NO3
type: Species

428301
stoichiometry: 1.0
species: 286102
type: SpeciesReference

406776
stoichiometry: 1.0
species: 285125
type: SpeciesReference

414932
stoichiometry: 1.0
species: 284796
type: SpeciesReference

290512
reactant: 431919
product: 431979
product: 431991
type: Reaction
kinetic law: 432003
product: 431967
reversible: true
reactant: 431955
notes: GENE_ASSOCIATION: YNR050C PROTEIN_ASSOCIATION: Lys9 SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.5.1.10
reactant: 431931
fast: false
name: R_saccharopine_dehydrogenase__NADP__L_glutamate_forming_
reactant: 431943

350472
stoichiometry: 1.0
species: 283500
type: SpeciesReference

301575
value: 0.0
type: LocalParameter

292165
value: 999999.0
type: LocalParameter

299403
value: 0.0
type: LocalParameter

285041
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indole_3_ethanol_C10H11NO
type: Species

297808
value: 0.0
type: LocalParameter

362059
stoichiometry: 1.0
species: 283905
type: SpeciesReference

385959
stoichiometry: 1.0
species: 284001
type: SpeciesReference

383298
stoichiometry: 1.0
species: 284873
type: SpeciesReference

302039
value: 0.0
type: LocalParameter

353586
stoichiometry: 1.0
species: 283050
type: SpeciesReference

436445
stoichiometry: 1.0
species: 284790
type: SpeciesReference

356364
stoichiometry: 1.0
species: 283725
type: SpeciesReference

402908
stoichiometry: 1.0
species: 284978
type: SpeciesReference

283962
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Citrate_C6H5O7
type: Species

368866
stoichiometry: 1.0
species: 284178
type: SpeciesReference

282888
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

419021
stoichiometry: 1.0
species: 284796
type: SpeciesReference

431943
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298477
value: 0.0
type: LocalParameter

345787
stoichiometry: 1.0
species: 283191
type: SpeciesReference

419324
stoichiometry: 1.0
species: 285595
type: SpeciesReference

284705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Guanosine_C10H13N5O5
type: Species

299402
value: -0.011879
type: LocalParameter

287152
kinetic law: 345763
product: 345751
reactant: 345739
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_methylbutanal_transport__extracellular_
type: Reaction

283338
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_methylzymosterol_C28H46O
type: Species

297807
value: 0.0
type: LocalParameter

380849
stoichiometry: 1.0
species: 286414
type: SpeciesReference

288488
kinetic law: 374415
product: 374403
reactant: 374390
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_methyl_1_butanol_exchange
type: Reaction

302037
value: 0.0
type: LocalParameter

289530
kinetic law: 400228
product: 400216
reactant: 400203
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_hexadecenoate__n_C161__transport_in_via_uniport
type: Reaction

282889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_10_Formyltetrahydrofolate_C20H21N7O7
type: Species

290514
name: R_saccharopine_dehydrogenase__NAD__L_lysine_forming_
product: 432089
product: 432053
type: Reaction
reactant: 432028
reactant: 432015
product: 432065
reversible: true
product: 432077
reactant: 432041
notes: GENE_ASSOCIATION: YIR034C PROTEIN_ASSOCIATION: Lys1 SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.5.1.7
kinetic law: 432101
fast: false

292163
value: 0.0
type: LocalParameter

284702
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Guanosine_C10H13N5O5
type: Species

436724
stoichiometry: 1.0
species: 283827
type: SpeciesReference

289103
name: R_fatty_acid_oxidation__tetradecansoyl_CoA___peroxisomal
reactant: 384794
reactant: 384819
notes: GENE_ASSOCIATION: ( YKR009C and YIL160C and YGL205W ) PROTEIN_ASSOCIATION: ( Fox2-p and Pot1-p and Pox1-p ) SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS:
reactant: 384843
reactant: 384807
product: 384880
fast: false
product: 384867
kinetic law: 384916
product: 384904
product: 384855
type: Reaction
reactant: 384831
reversible: false
product: 384892

418491
stoichiometry: 1.0
species: 285529
type: SpeciesReference

297229
value: 999999.0
type: LocalParameter

292058
value: 0.0
type: LocalParameter

293976
value: 0.0
type: LocalParameter

293863
value: 0.0
type: LocalParameter

362627
stoichiometry: 1.0
species: 283920
type: SpeciesReference

289101
name: R_Fatty_acid_oxidation
product: 384758
reactant: 384721
product: 384745
product: 384770
reversible: false
kinetic law: 384782
fast: false
reactant: 384709
type: Reaction
reactant: 384697
reactant: 384673
notes: GENE_ASSOCIATION: ( ( YLR284C and YKR009C and YIL160C and YGL205W ) or ( YOR180C and YKR009C and YIL160C and YGL205W ) ) PROTEIN_ASSOCIATION: ( Eci1-p and Fox2-p and Pot1-p and Pox1-p ) or ( Dci1-p and Fox2-p and Pot1-p and Pox1-p ) SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS:
reactant: 384685
product: 384733

297806
value: 999999.0
type: LocalParameter

298474
value: 0.0
type: LocalParameter

303750
value: -0.168681
type: LocalParameter

348747
stoichiometry: 1.0
species: 283077
type: SpeciesReference

423392
stoichiometry: 1.0
species: 285763
type: SpeciesReference

302036
value: 999999.0
type: LocalParameter

298475
value: 0.236185
type: LocalParameter

352670
stoichiometry: 1.0
species: 284001
type: SpeciesReference

374862
stoichiometry: 1.0
species: 283515
type: SpeciesReference

353260
stoichiometry: 1.0
species: 283659
type: SpeciesReference

374717
stoichiometry: 1.0
species: 283413
type: SpeciesReference

299404
value: 999999.0
type: LocalParameter

293975
value: 0.0
type: LocalParameter

283815
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_L_Aspartate_C4H6NO4
type: Species

301574
value: 999999.0
type: LocalParameter

302387
value: 3.0E-5
type: LocalParameter

302246
value: 0.0
type: LocalParameter

443512
stoichiometry: 6.0E-6
species: 285613
type: SpeciesReference

283980
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_3_Carboxy_3__methylammonio_propyl_L_histidine_C11H18N4O4
type: Species

387731
stoichiometry: 1.0
species: 284001
type: SpeciesReference

283566
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_O_Acetylcarnitine_C9H17NO4
type: Species

365804
stoichiometry: 1.0
species: 285508
type: SpeciesReference

300629
value: 999999.0
type: LocalParameter

404180
stoichiometry: 1.0
species: 284787
type: SpeciesReference

386803
stoichiometry: 1.0
species: 285487
type: SpeciesReference

384324
stoichiometry: 9.0
species: 283530
type: SpeciesReference

428954
stoichiometry: 1.0
species: 284744
type: SpeciesReference

289978
notes: GENE_ASSOCIATION: YLR138W PROTEIN_ASSOCIATION: Nha1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
type: Reaction
reversible: true
reactant: 415004
fast: false
kinetic law: 415053
product: 415029
name: R_sodium_proton_antiporter__HNA_is_11_
reactant: 415016
product: 415041

371407
stoichiometry: 1.0
species: 282959
type: SpeciesReference

288629
kinetic law: 376116
product: 376104
reactant: 376092
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Ergosterol_exchange
type: Reaction

303767
value: 999999.0
type: LocalParameter

294809
value: 0.0
type: LocalParameter

442884
stoichiometry: 0.01
species: 284867
type: SpeciesReference

292268
value: 0.0
type: LocalParameter

303765
value: -999999.0
type: LocalParameter

302247
value: 0.028496
type: LocalParameter

293536
value: 0.0
type: LocalParameter

357834
stoichiometry: 1.0
species: 285796
type: SpeciesReference

289550
product: 400844
type: Reaction
kinetic law: 400880
notes: GENE_ASSOCIATION: YIL094C PROTEIN_ASSOCIATION: Lys12-m SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.1.1.155
reactant: 400832
product: 400856
fast: false
name: R_homoisocitrate_dehydrogenase
reactant: 400820
reversible: true
product: 400868

297237
value: 999999.0
type: LocalParameter

289107
product: 385135
reversible: false
kinetic law: 385159
name: R_fatty_acid_synthase__n_C100_
reactant: 385051
product: 385099
reactant: 385063
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
product: 385123
product: 385111
type: Reaction
reactant: 385075
fast: false
product: 385147
reactant: 385087

435779
stoichiometry: 1.0
species: 283992
type: SpeciesReference

369665
stoichiometry: 1.0
species: 285955
type: SpeciesReference

292863
value: 0.0
type: LocalParameter

362288
stoichiometry: 1.0
species: 284802
type: SpeciesReference

287134
kinetic law: 345449
product: 345437
type: Reaction
reversible: false
fast: false
reactant: 345388
product: 345425
product: 345413
name: R_S_adenosyl_L_methionine3_hexaprenyl_4_5_dihydroxylate_O_methyltransferase__mitochondrial
notes: GENE_ASSOCIATION: ( YOL096C and YDR204W and YML110C and YGR255C and YOR125C and YGL119W and YLR201C ) PROTEIN_ASSOCIATION: ( Coq3-m and Coq4-m and Coq5-m and Coq6-m and Coq7-m and Coq8-m and Coq9-m ) SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
reactant: 345401

410724
stoichiometry: 1.0
species: 283395
type: SpeciesReference

289263
type: Reaction
product: 391737
name: R_glutamate_5_semialdehyde_dehydrogenase
fast: false
product: 391761
kinetic law: 391773
reversible: false
notes: GENE_ASSOCIATION: YOR323C PROTEIN_ASSOCIATION: Pro2 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.41
product: 391749
reactant: 391701
reactant: 391713
reactant: 391725

426074
stoichiometry: 1.0
species: 285622
type: SpeciesReference

293120
value: 0.0
type: LocalParameter

357221
stoichiometry: 1.0
species: 286276
type: SpeciesReference

294808
value: 0.0
type: LocalParameter

433165
stoichiometry: 1.0
species: 284787
type: SpeciesReference

429593
stoichiometry: 2.0
species: 284757
type: SpeciesReference

300627
value: -0.011879
type: LocalParameter

297238
value: 0.0
type: LocalParameter

299418
value: 999999.0
type: LocalParameter

303764
value: 0.0
type: LocalParameter

302389
value: 0.0
type: LocalParameter

435900
stoichiometry: 1.0
species: 284775
type: SpeciesReference

285796
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Diphosphate_HO7P2
type: Species

301584
value: 0.0
type: LocalParameter

376176
stoichiometry: 1.0
species: 286720
type: SpeciesReference

362976
stoichiometry: 1.0
species: 286393
type: SpeciesReference

356691
stoichiometry: 1.0
species: 283749
type: SpeciesReference

348675
stoichiometry: 1.0
species: 283524
type: SpeciesReference

289976
product: 414968
kinetic law: 414992
reactant: 414932
notes: GENE_ASSOCIATION: YOR209C PROTEIN_ASSOCIATION: Npt1-m SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 2.4.2.11
reactant: 414956
reactant: 414944
type: Reaction
name: R_NAPRTase__mitochondrial
fast: false
product: 414980
reversible: false

420363
stoichiometry: 1.0
species: 282893
type: SpeciesReference

379350
stoichiometry: 1.0
species: 286981
type: SpeciesReference

302249
value: 0.0
type: LocalParameter

397173
stoichiometry: 1.0
species: 283713
type: SpeciesReference

284930
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Homoserine_C4H9NO3
type: Species

297239
value: 0.0
type: LocalParameter

283983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_CMP_C9H12N3O8P
type: Species

283452
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_N_bisformyl_dityrosine_C20H22N2O8
type: Species

293538
value: 0.0
type: LocalParameter

411364
stoichiometry: 1.0
species: 284799
type: SpeciesReference

303763
value: 0.0
type: LocalParameter

292865
value: -0.121561
type: LocalParameter

439193
stoichiometry: 1.0
species: 284618
type: SpeciesReference

301583
value: 999999.0
type: LocalParameter

287131
kinetic law: 345376
product: 345364
reactant: 345352
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_Carboxy_4_methyl_2_oxopentanoate_transport__diffusion__mitochondrial
type: Reaction

414605
stoichiometry: 1.0
species: 285424
type: SpeciesReference

289105
reactant: 384928
product: 384990
product: 385014
reactant: 384966
reversible: false
kinetic law: 385039
reactant: 384953
fast: false
product: 385027
notes: GENE_ASSOCIATION: ( YKR009C and YIL160C and YGL205W ) PROTEIN_ASSOCIATION: ( Fox2-p and Pot1-p and Pox1-p ) SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS:
reactant: 384940
reactant: 384978
name: R_fatty_acid_oxidation__octanoyl_CoA___peroxisomal
type: Reaction
product: 385002

373991
stoichiometry: 1.0
species: 283830
type: SpeciesReference

401637
stoichiometry: 1.0
species: 283521
type: SpeciesReference

300628
value: 0.0
type: LocalParameter

301439
value: 999999.0
type: LocalParameter

289261
type: Reaction
product: 391653
fast: false
product: 391677
kinetic law: 391689
name: R_L_glutamate_5_semialdehyde_dehydratase__reversible__mitochondrial
reactant: 391641
product: 391665
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS:
reversible: true

407468
stoichiometry: 3.0
species: 285487
type: SpeciesReference

293122
value: 999999.0
type: LocalParameter

384892
stoichiometry: 3.0
species: 285418
type: SpeciesReference

395543
stoichiometry: 1.0
species: 284618
type: SpeciesReference

399849
stoichiometry: 1.0
species: 284817
type: SpeciesReference

292866
value: 0.0
type: LocalParameter

292370
value: 0.0
type: LocalParameter

284933
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Tetrahydropteroyltri_L_glutamate_C24H34N8O12
type: Species

284828
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hexadecanoate__n_C160__C16H31O2
type: Species

375706
stoichiometry: 1.0
species: 286681
type: SpeciesReference

282882
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

365901
stoichiometry: 1.0
species: 283971
type: SpeciesReference

302242
value: 0.0
type: LocalParameter

300625
value: 0.0
type: LocalParameter

297231
value: 0.0
type: LocalParameter

363785
stoichiometry: 2.0
species: 284757
type: SpeciesReference

352538
stoichiometry: 1.0
species: 284478
type: SpeciesReference

285571
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

381790
stoichiometry: 1.0
species: 283416
type: SpeciesReference

400143
stoichiometry: 1.0
species: 284827
type: SpeciesReference

289974
reactant: 414872
fast: false
notes: GENE_ASSOCIATION: YOR209C PROTEIN_ASSOCIATION: Npt1 SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 2.4.2.11
reversible: false
type: Reaction
reactant: 414860
name: R_NAPRTase
kinetic law: 414920
product: 414896
product: 414908
reactant: 414884

346597
stoichiometry: 1.0
species: 284319
type: SpeciesReference

403949
stoichiometry: 1.0
species: 284805
type: SpeciesReference

293532
value: 999999.0
type: LocalParameter

285799
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Diphosphate_HO7P2
type: Species

421887
stoichiometry: 1.0
species: 283401
type: SpeciesReference

292264
value: 999999.0
type: LocalParameter

436518
stoichiometry: 1.0
species: 286186
type: SpeciesReference

284827
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_L_Homocysteine_C4H9NO2S
type: Species

297233
value: 0.0
type: LocalParameter

439700
stoichiometry: 1.0
species: 286417
type: SpeciesReference

344919
stoichiometry: 1.0
species: 283083
type: SpeciesReference

302243
value: 0.0
type: LocalParameter

302130
value: 0.0
type: LocalParameter

396859
stoichiometry: 1.0
species: 285159
type: SpeciesReference

400868
stoichiometry: 1.0
species: 285610
type: SpeciesReference

366694
stoichiometry: 1.0
species: 285952
type: SpeciesReference

288626
kinetic law: 376080
product: 376068
reactant: 376056
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_episterol_ester__yeast_specific_exchange
type: Reaction

301580
value: -999999.0
type: LocalParameter

285574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

403877
stoichiometry: 1.0
species: 284790
type: SpeciesReference

292868
value: 999999.0
type: LocalParameter

302131
value: 0.0
type: LocalParameter

363012
stoichiometry: 1.0
species: 284787
type: SpeciesReference

302244
value: 999999.0
type: LocalParameter

288391
kinetic law: 372364
product: 372352
reactant: 372340
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_erythrose_4_phosphate_mtiochondrial_transport_via_diffusion
type: Reaction

427754
stoichiometry: 1.0
species: 285862
type: SpeciesReference

436215
stoichiometry: 2.0
species: 284766
type: SpeciesReference

289972
kinetic law: 414848
product: 414836
reactant: 414824
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_NAD_transport__nuclear_through_pores
type: Reaction

287137
kinetic law: 345485
product: 345473
reactant: 345461
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_Hexaprenyl_4_5_dihydroxybenzoate_transport__mitochondrial
type: Reaction

292266
value: 0.0
type: LocalParameter

283569
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_O_Acetylcarnitine_C9H17NO4
type: Species

289109
reactant: 385195
product: 385244
reactant: 385208
product: 385268
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
product: 385220
reactant: 385171
product: 385232
kinetic law: 385280
fast: false
type: Reaction
reactant: 385183
name: R_fatty_acyl_ACP_synthase__n_C100ACP___mitochondrial
reversible: false
product: 385256

292371
value: 0.0
type: LocalParameter

302132
value: 999999.0
type: LocalParameter

300624
value: 0.0
type: LocalParameter

293534
value: 0.0
type: LocalParameter

297235
value: 0.0
type: LocalParameter

385425
stoichiometry: 3.0
species: 284787
type: SpeciesReference

379060
stoichiometry: 1.0
species: 286957
type: SpeciesReference

284720
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Reduced_glutathione_C10H16N3O6S
type: Species

303768
value: 0.0
type: LocalParameter

356571
stoichiometry: 1.0
species: 285487
type: SpeciesReference

297121
value: -0.06573
type: LocalParameter

426388
stoichiometry: 1.0
species: 283830
type: SpeciesReference

362832
stoichiometry: 1.0
species: 286069
type: SpeciesReference

297801
value: 0.0
type: LocalParameter

298774
value: 0.0
type: LocalParameter

296712
value: 0.0
type: LocalParameter

297955
value: 0.0
type: LocalParameter

298034
value: 999999.0
type: LocalParameter

400252
stoichiometry: 1.0
species: 285412
type: SpeciesReference

287248
kinetic law: 347505
product: 347493
reactant: 347481
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_arabinitol_transport_via_passive_diffusion
type: Reaction

427113
stoichiometry: 1.0
species: 284793
type: SpeciesReference

426232
stoichiometry: 1.0
species: 283638
type: SpeciesReference

297123
value: 0.0
type: LocalParameter

300734
value: 0.0
type: LocalParameter

442715
stoichiometry: 0.01
species: 284876
type: SpeciesReference

291493
value: 0.0
type: LocalParameter

290650
kinetic law: 436591
product: 436579
reactant: 436567
notes: GENE_ASSOCIATION: YGR096W PROTEIN_ASSOCIATION: Tpc1-m SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_Thiamine_diphosphate_transport__mitochondria
type: Reaction

292261
value: 0.0
type: LocalParameter

298035
value: 0.0
type: LocalParameter

390251
stoichiometry: 1.0
species: 284490
type: SpeciesReference

393802
stoichiometry: 1.0
species: 284544
type: SpeciesReference

284824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Homocysteine_C4H9NO2S
type: Species

298773
value: 0.0
type: LocalParameter

381682
stoichiometry: 1.0
species: 283845
type: SpeciesReference

293128
value: 0.0
type: LocalParameter

298033
value: 0.0
type: LocalParameter

297956
value: 999999.0
type: LocalParameter

296711
value: 0.0
type: LocalParameter

302134
value: 0.0
type: LocalParameter

288394
kinetic law: 372413
product: 372400
reactant: 372388
reactant: 372376
notes: GENE_ASSOCIATION: YKR009C PROTEIN_ASSOCIATION: Fox2-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 4.2.1.17
fast: false
reversible: true
name: R_3_hydroxyacyl_CoA_dehydratase__3_hydroxyhexacosyl_CoA___peroxisomal
type: Reaction

369960
stoichiometry: 1.0
species: 284226
type: SpeciesReference

351173
stoichiometry: 1.0
species: 285095
type: SpeciesReference

293423
value: 999999.0
type: LocalParameter

300735
value: 999999.0
type: LocalParameter

284823
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Bicarbonate_CHO3
type: Species

302380
value: 0.0
type: LocalParameter

380704
stoichiometry: 1.0
species: 286159
type: SpeciesReference

292373
value: 999999.0
type: LocalParameter

367057
stoichiometry: 1.0
species: 283983
type: SpeciesReference

289970
product: 414776
kinetic law: 414812
type: Reaction
reactant: 414727
fast: false
product: 414800
reversible: false
reactant: 414752
name: R_NAD_synthase__nh3___nuclear
notes: GENE_ASSOCIATION: YHR074W PROTEIN_ASSOCIATION: Qns1-n SUBSYSTEM: S_NAD_Biosynthesis PROTEIN_CLASS: 6.3.1.5
product: 414764
reactant: 414740
product: 414788

421996
stoichiometry: 1.0
species: 284766
type: SpeciesReference

284936
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hypoxanthine_C5H4N4O
type: Species

375814
stoichiometry: 1.0
species: 286690
type: SpeciesReference

285682
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
type: Species

297957
value: 0.0
type: LocalParameter

293129
value: -999999.0
type: LocalParameter

284939
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Hypoxanthine_C5H4N4O
type: Species

381054
stoichiometry: 1.0
species: 285778
type: SpeciesReference

296710
value: 999999.0
type: LocalParameter

363120
stoichiometry: 1.0
species: 285883
type: SpeciesReference

417956
stoichiometry: 1.0
species: 285032
type: SpeciesReference

288518
kinetic law: 374777
product: 374765
reactant: 374753
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_N_N_bisformyl_dityrosine_exchange
type: Reaction

302240
value: 0.019085
type: LocalParameter

291491
value: 0.0
type: LocalParameter

388397
stoichiometry: 1.0
species: 284418
type: SpeciesReference

297125
value: 999999.0
type: LocalParameter

302135
value: 0.0
type: LocalParameter

284612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Glutamate_5_semialdehyde_C5H9NO3
type: Species

301431
value: 0.0
type: LocalParameter

298037
value: 0.0
type: LocalParameter

289269
reversible: false
reactant: 391930
name: R_glucose_6_phosphate_dehydrogenase
kinetic law: 391990
type: Reaction
product: 391978
product: 391954
notes: GENE_ASSOCIATION: YNL241C PROTEIN_ASSOCIATION: Zwf1 SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 1.1.1.49
fast: false
reactant: 391942
product: 391966

288974
kinetic law: 380341
product: 380329
reactant: 380317
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport
type: Reaction

403720
stoichiometry: 1.0
species: 285008
type: SpeciesReference

425400
stoichiometry: 1.0
species: 283353
type: SpeciesReference

298775
value: 0.0
type: LocalParameter

295043
value: 0.0
type: LocalParameter

287245
type: Reaction
reversible: false
reactant: 347432
product: 347444
name: R_4_aminobutyrate_transaminase
reactant: 347420
product: 347457
fast: false
notes: GENE_ASSOCIATION: YGR019W PROTEIN_ASSOCIATION: Uga1 SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 2.6.1.19
kinetic law: 347469

396700
stoichiometry: 1.0
species: 283830
type: SpeciesReference

294919
value: 0.0
type: LocalParameter

297230
value: 0.0
type: LocalParameter

356462
stoichiometry: 1.0
species: 283992
type: SpeciesReference

293425
value: 0.0
type: LocalParameter

297126
value: 0.0
type: LocalParameter

384048
stoichiometry: 6.0
species: 285499
type: SpeciesReference

300733
value: 0.0
type: LocalParameter

292375
value: 0.0
type: LocalParameter

301430
value: 999999.0
type: LocalParameter

415815
stoichiometry: 1.0
species: 283602
type: SpeciesReference

295042
value: 0.0
type: LocalParameter

389490
stoichiometry: 1.0
species: 284448
type: SpeciesReference

292262
value: -999999.0
type: LocalParameter

432415
stoichiometry: 1.0
species: 284787
type: SpeciesReference

302382
value: 0.0
type: LocalParameter

297951
value: 0.0
type: LocalParameter

395699
stoichiometry: 1.0
species: 285409
type: SpeciesReference

386094
stoichiometry: 1.0
species: 284757
type: SpeciesReference

302138
value: -999999.0
type: LocalParameter

406620
stoichiometry: 1.0
species: 284790
type: SpeciesReference

437488
stoichiometry: 1.0
species: 283554
type: SpeciesReference

301434
value: 0.0
type: LocalParameter

350099
stoichiometry: 1.0
species: 283830
type: SpeciesReference

293337
value: -0.030885
type: LocalParameter

404071
stoichiometry: 1.0
species: 285008
type: SpeciesReference

300738
value: 0.0
type: LocalParameter

298039
value: 0.0
type: LocalParameter

293539
value: 0.0
type: LocalParameter

302137
value: -0.011879
type: LocalParameter

405339
stoichiometry: 1.0
species: 283935
type: SpeciesReference

387840
stoichiometry: 3.0
species: 283992
type: SpeciesReference

297127
value: 0.0
type: LocalParameter

290654
name: R_Thiamine_transport_in_via_proton_symport
reactant: 436676
reactant: 436663
fast: false
product: 436688
kinetic law: 436712
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: ( YLR237W or YOR071C or YOR192C ) PROTEIN_ASSOCIATION: ( Thi7 ) or ( Thm1 ) or ( Thm2 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 436700

302383
value: -999999.0
type: LocalParameter

284820
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Bicarbonate_CHO3
type: Species

288397
kinetic law: 372461
product: 372449
product: 372437
reactant: 372425
notes: GENE_ASSOCIATION: YKR009C PROTEIN_ASSOCIATION: Fox2-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 4.2.1.17
fast: false
reversible: true
name: R_3_hydroxyacyl_CoA_dehydratase__3_hydroxydecanoyl_CoA___peroxisomal
type: Reaction

297952
value: 0.0
type: LocalParameter

421512
stoichiometry: 1.0
species: 283830
type: SpeciesReference

302139
value: 999999.0
type: LocalParameter

293124
value: 0.0
type: LocalParameter

388248
stoichiometry: 1.0
species: 285517
type: SpeciesReference

289267
name: R_glucosamine_6_phosphate_deaminase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 3.5.99.6
reactant: 391882
kinetic law: 391918
fast: false
reversible: false
product: 391906
product: 391894
reactant: 391869
type: Reaction

293338
value: 0.0
type: LocalParameter

295049
value: 0.0
type: LocalParameter

435888
stoichiometry: 1.0
species: 283842
type: SpeciesReference

372388
stoichiometry: 1.0
species: 284942
type: SpeciesReference

300739
value: 0.0
type: LocalParameter

298038
value: 0.0
type: LocalParameter

366538
stoichiometry: 1.0
species: 284058
type: SpeciesReference

283458
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N_Formyl_L_tyrosine_C10H10NO4
type: Species

287242
reactant: 347360
type: Reaction
product: 347384
reversible: true
fast: false
kinetic law: 347408
reactant: 347372
product: 347396
name: R_2_aminoadipate_transaminase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.6.1.39

292377
value: 0.0
type: LocalParameter

291496
value: -999999.0
type: LocalParameter

293427
value: 0.0
type: LocalParameter

357943
stoichiometry: 1.0
species: 283788
type: SpeciesReference

302384
value: 999999.0
type: LocalParameter

283563
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_N2_Acetyl_L_ornithine_C7H14N2O3
type: Species

395471
stoichiometry: 1.0
species: 283602
type: SpeciesReference

372170
stoichiometry: 1.0
species: 285943
type: SpeciesReference

294916
value: 999999.0
type: LocalParameter

436881
stoichiometry: 1.0
species: 283077
type: SpeciesReference

358475
stoichiometry: 1.0
species: 283830
type: SpeciesReference

288971
product: 380281
fast: false
reactant: 380245
kinetic law: 380305
product: 380269
reactant: 380257
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 3.1.2.14
product: 380293
reversible: true
name: R_fatty_acyl_ACP_hydrolase
type: Reaction

301436
value: -999999.0
type: LocalParameter

295046
value: 999999.0
type: LocalParameter

410663
stoichiometry: 1.0
species: 283884
type: SpeciesReference

298771
value: 0.0
type: LocalParameter

293650
value: 0.0
type: LocalParameter

401529
stoichiometry: 2.0
species: 285421
type: SpeciesReference

283455
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_N_N_bisformyl_dityrosine_C20H22N2O8
type: Species

290652
reactant: 436603
product: 436627
fast: false
reactant: 436615
notes: GENE_ASSOCIATION: YBR092C PROTEIN_ASSOCIATION: Pho3-e SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 3.1.3.2
reversible: false
name: R_thiamin_phosphatase__extracellular
kinetic law: 436651
product: 436639
type: Reaction

297129
value: -0.063552
type: LocalParameter

299309
value: 0.019085
type: LocalParameter

418599
stoichiometry: 1.0
species: 284388
type: SpeciesReference

291495
value: 0.0
type: LocalParameter

283560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_trans_Aconitate_C6H3O6
type: Species

442994
stoichiometry: 0.02
species: 284831
type: SpeciesReference

297954
value: -0.005543
type: LocalParameter

344396
stoichiometry: 1.0
species: 283629
type: SpeciesReference

376068
stoichiometry: 1.0
species: 286711
type: SpeciesReference

289265
kinetic law: 391857
type: Reaction
reactant: 391797
product: 391821
product: 391845
product: 391833
reactant: 391809
name: R_glutamate_5_semialdehyde_dehydrogenase
reversible: false
notes: GENE_ASSOCIATION: YOR323C PROTEIN_ASSOCIATION: Pro2 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.41
fast: false
reactant: 391785

293126
value: 0.0
type: LocalParameter

407359
stoichiometry: 1.0
species: 285140
type: SpeciesReference

301435
value: 0.0
type: LocalParameter

426655
stoichiometry: 1.0
species: 285835
type: SpeciesReference

410879
stoichiometry: 1.0
species: 283626
type: SpeciesReference

298770
value: 999999.0
type: LocalParameter

411473
stoichiometry: 1.0
species: 285751
type: SpeciesReference

302386
value: 0.0
type: LocalParameter

429485
stoichiometry: 1.0
species: 283602
type: SpeciesReference

292379
value: -0.041576
type: LocalParameter

293429
value: 0.0
type: LocalParameter

292861
value: 0.0
type: LocalParameter

283341
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boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Methylzymosterol_intermediate_1_C29H46O3
type: Species

299308
value: 0.0
type: LocalParameter

393960
stoichiometry: 1.0
species: 286030
type: SpeciesReference

294913
value: 0.0
type: LocalParameter

292042
value: 0.0
type: LocalParameter

428809
stoichiometry: 1.0
species: 284079
type: SpeciesReference

293346
value: 0.0
type: LocalParameter

348253
stoichiometry: 1.0
species: 283830
type: SpeciesReference

401061
stoichiometry: 1.0
species: 286306
type: SpeciesReference

351017
stoichiometry: 2.0
species: 283608
type: SpeciesReference

396920
stoichiometry: 1.0
species: 283830
type: SpeciesReference

298352
value: 999999.0
type: LocalParameter

289650
product: 404022
fast: false
reversible: false
notes: GENE_ASSOCIATION: ( YKL146W or YNL101W ) PROTEIN_ASSOCIATION: ( Avt3-v ) or ( Avt4-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
kinetic law: 404047
type: Reaction
reactant: 403998
reactant: 404010
product: 404034
name: R_L_isoleucine_transport_out_via_proton_symport__vacuolar

298467
value: 0.0
type: LocalParameter

298354
value: 0.0
type: LocalParameter

434523
stoichiometry: 1.0
species: 283467
type: SpeciesReference

302020
value: 0.0
type: LocalParameter

353381
stoichiometry: 1.0
species: 284787
type: SpeciesReference

290658
kinetic law: 436809
product: 436797
product: 436785
reactant: 436772
notes: GENE_ASSOCIATION: YEL046C PROTEIN_ASSOCIATION: Gly1 SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.2.5
fast: false
reversible: false
name: R_Threonine_aldolase
type: Reaction

293640
value: 0.0
type: LocalParameter

291489
value: 999999.0
type: LocalParameter

287251
fast: false
type: Reaction
product: 347566
name: R_Aminobutyraldehyde_dehydrogenase__mitochondrial
reactant: 347517
reactant: 347529
reactant: 347542
kinetic law: 347590
reversible: false
notes: GENE_ASSOCIATION: ( YOR374W or YER073W ) PROTEIN_ASSOCIATION: ( Ald4-m ) or ( Ald5-m ) SUBSYSTEM: S_Other_Amino_Acid_Metabolism PROTEIN_CLASS: 1.2.1.19
product: 347554
product: 347578

293854
value: -0.076083
type: LocalParameter

292156
value: 999999.0
type: LocalParameter

284606
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glycylpeptide_C4H7N2O3R
type: Species

296708
value: 0.0
type: LocalParameter

356124
stoichiometry: 1.0
species: 284787
type: SpeciesReference

412162
stoichiometry: 0.01
species: 285327
type: SpeciesReference

302023
value: 0.0
type: LocalParameter

291486
value: 0.0
type: LocalParameter

298468
value: 0.0
type: LocalParameter

293643
value: 999999.0
type: LocalParameter

428508
stoichiometry: 1.0
species: 283836
type: SpeciesReference

298355
value: 0.0
type: LocalParameter

421440
stoichiometry: 1.0
species: 283830
type: SpeciesReference

282879
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

439048
stoichiometry: 1.0
species: 285487
type: SpeciesReference

292044
value: 0.0
type: LocalParameter

293962
value: 0.0
type: LocalParameter

293857
value: -999999.0
type: LocalParameter

299306
value: 999999.0
type: LocalParameter

287800
product: 359348
kinetic law: 359373
fast: false
reactant: 359312
notes: GENE_ASSOCIATION: YDR530C PROTEIN_ASSOCIATION: Apa2 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.7.53
reactant: 359324
name: R_ATP_adenylyltransferase
reversible: false
product: 359360
reactant: 359336
type: Reaction

356244
stoichiometry: 1.0
species: 283719
type: SpeciesReference

294912
value: 0.0
type: LocalParameter

290656
kinetic law: 436760
product: 436748
product: 436736
reactant: 436724
notes: GENE_ASSOCIATION: YEL046C PROTEIN_ASSOCIATION: Gly1 SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.2.5
fast: false
reversible: false
name: R_L_allo_Threonine_Aldolase
type: Reaction

397017
stoichiometry: 1.0
species: 284787
type: SpeciesReference

302022
value: 999999.0
type: LocalParameter

391785
stoichiometry: 1.0
species: 284609
type: SpeciesReference

404396
stoichiometry: 1.0
species: 283830
type: SpeciesReference

419469
stoichiometry: 1.0
species: 285853
type: SpeciesReference

350376
stoichiometry: 1.0
species: 284787
type: SpeciesReference

292158
value: 0.0
type: LocalParameter

292045
value: -999999.0
type: LocalParameter

291487
value: 0.0
type: LocalParameter

293856
value: 0.0
type: LocalParameter

299305
value: 0.0
type: LocalParameter

298040
value: 999999.0
type: LocalParameter

296706
value: -0.047516
type: LocalParameter

293347
value: 0.0
type: LocalParameter

394374
stoichiometry: 1.0
species: 285751
type: SpeciesReference

353489
stoichiometry: 1.0
species: 285421
type: SpeciesReference

299304
value: 0.0
type: LocalParameter

429269
stoichiometry: 1.0
species: 284747
type: SpeciesReference

418089
stoichiometry: 1.0
species: 285454
type: SpeciesReference

399913
stoichiometry: 1.0
species: 284820
type: SpeciesReference

293645
value: 0.0
type: LocalParameter

300743
value: 999999.0
type: LocalParameter

361695
stoichiometry: 1.0
species: 283872
type: SpeciesReference

357378
stoichiometry: 1.0
species: 284787
type: SpeciesReference

380546
stoichiometry: 1.0
species: 284808
type: SpeciesReference

287806
reactant: 359457
fast: false
product: 359494
product: 359506
reactant: 359469
notes: GENE_ASSOCIATION: YCL050C PROTEIN_ASSOCIATION: Apa1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.7.53
kinetic law: 359518
type: Reaction
name: R_ATP_adenylyltransferase
reactant: 359481
reversible: false

394178
stoichiometry: 1.0
species: 284690
type: SpeciesReference

293342
value: 0.0
type: LocalParameter

289656
reversible: false
name: R_IMP_dehydrogenase
reactant: 404168
reactant: 404144
product: 404192
product: 404204
reactant: 404156
product: 404180
notes: GENE_ASSOCIATION: ( YHR216W or YLR432W or YAR075W or YML056C or YAR073W ) PROTEIN_ASSOCIATION: ( Imd2 ) or ( Imd3 ) or ( Imd5 ) or ( Imd4 ) or ( Imd1 ) SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.1.1.205
type: Reaction
fast: false
kinetic law: 404216

442171
stoichiometry: 1.0
species: 286495
type: SpeciesReference

298777
value: 999999.0
type: LocalParameter

348301
stoichiometry: 1.0
species: 285219
type: SpeciesReference

296703
value: 0.0
type: LocalParameter

297948
value: 0.0
type: LocalParameter

284602
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
name: M_L_Glutamine_C5H10N2O3
type: Species

283239
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_5_O__1_Carboxyvinyl__3_phosphoshikimate_C10H9O10P
type: Species

285685
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

405230
stoichiometry: 0.01
species: 285898
type: SpeciesReference

293430
value: 0.0
type: LocalParameter

293757
value: 999999.0
type: LocalParameter

283344
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Methylzymosterol_intermediate_2_C28H44O
type: Species

300742
value: 0.0
type: LocalParameter

400591
stoichiometry: 1.0
species: 285237
type: SpeciesReference

298778
value: 0.0
type: LocalParameter

298042
value: 0.0
type: LocalParameter

297947
value: 0.0
type: LocalParameter

293119
value: 0.0
type: LocalParameter

285059
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Inosine_C10H12N4O5
type: Species

296704
value: 0.0
type: LocalParameter

288512
kinetic law: 374704
product: 374692
reactant: 374680
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_5_Amino_4_oxopentanoate_exchange
type: Reaction

288977
kinetic law: 380378
product: 380366
reactant: 380354
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport
type: Reaction

285688
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282888
type: Species

389199
stoichiometry: 1.0
species: 284760
type: SpeciesReference

302390
value: -999999.0
type: LocalParameter

299302
value: 0.108669
type: LocalParameter

412017
stoichiometry: 0.01
species: 285898
type: SpeciesReference

284603
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Glutaminyl_tRNA_Gln__C5H9N2O2R
type: Species

292040
value: 0.0
type: LocalParameter

378115
stoichiometry: 1.0
species: 286879
type: SpeciesReference

300741
value: -0.011879
type: LocalParameter

383807
stoichiometry: 6.0
species: 284808
type: SpeciesReference

423200
stoichiometry: 0.01
species: 285916
type: SpeciesReference

293647
value: 0.0
type: LocalParameter

405556
stoichiometry: 1.0
species: 283029
type: SpeciesReference

406066
stoichiometry: 1.0
species: 283659
type: SpeciesReference

289654
kinetic law: 404132
product: 404120
reactant: 404108
reactant: 404096
notes: GENE_ASSOCIATION: ( YLR028C or YMR120C ) PROTEIN_ASSOCIATION: ( Ade16 ) or ( Ade17 ) SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.5.4.10
fast: false
reversible: true
name: R_IMP_cyclohydrolase
type: Reaction

298350
value: -0.011285
type: LocalParameter

293344
value: 2.02E-4
type: LocalParameter

290508
kinetic law: 431871
product: 431859
reactant: 431847
notes: GENE_ASSOCIATION: YJL121C PROTEIN_ASSOCIATION: Rpe1 SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 5.1.3.1
fast: false
reversible: true
name: R_ribulose_5_phosphate_3_epimerase
type: Reaction

371517
stoichiometry: 1.0
species: 284283
type: SpeciesReference

288515
kinetic law: 374741
product: 374729
reactant: 374717
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_8_Amino_7_oxononanoate_exchange
type: Reaction

298043
value: 0.0
type: LocalParameter

392716
stoichiometry: 1.0
species: 284550
type: SpeciesReference

293432
value: 999999.0
type: LocalParameter

299301
value: 0.0
type: LocalParameter

283821
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Aspartyl_tRNA_Asp__C4H5NO3R
type: Species

422141
stoichiometry: 1.0
species: 282932
type: SpeciesReference

391074
stoichiometry: 1.0
species: 285195
type: SpeciesReference

293759
value: 0.0
type: LocalParameter

289652
kinetic law: 404084
product: 404071
reactant: 404059
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_Isoleucine_transport_from_mitochondria_to_cytosol
type: Reaction

287803
kinetic law: 359445
product: 359433
fast: false
reactant: 359385
reversible: false
name: R_ATP_adenylyltransferase
product: 359421
notes: GENE_ASSOCIATION: YCL050C PROTEIN_ASSOCIATION: Apa1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.7.53
type: Reaction
reactant: 359397
reactant: 359409

298351
value: -999999.0
type: LocalParameter

384564
stoichiometry: 1.0
species: 285445
type: SpeciesReference

289548
kinetic law: 400808
reversible: false
fast: false
product: 400784
name: R_Homogentisateoxygen_1_2_oxidoreductase__decyclizing_
reactant: 400760
type: Reaction
product: 400796
reactant: 400772
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.13.11.5

436663
stoichiometry: 1.0
species: 284790
type: SpeciesReference

353913
stoichiometry: 1.0
species: 284975
type: SpeciesReference

296702
value: 999999.0
type: LocalParameter

297949
value: 999999.0
type: LocalParameter

367490
stoichiometry: 1.0
species: 284088
type: SpeciesReference

285056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_myo_Inositol_C6H12O6
type: Species

435356
stoichiometry: 1.0
species: 286120
type: SpeciesReference

290506
fast: false
product: 431811
reversible: false
type: Reaction
reactant: 431774
product: 431823
reactant: 431787
product: 431799
name: R_ribonucleoside_triphosphate_reductase__UTP_
kinetic law: 431835
notes: GENE_ASSOCIATION: ( YLR043C or YGR209C ) PROTEIN_ASSOCIATION: ( Trx1 ) or ( Trx2 ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2

361586
stoichiometry: 2.0
species: 284747
type: SpeciesReference

293649
value: -0.438332
type: LocalParameter

379205
stoichiometry: 1.0
species: 286969
type: SpeciesReference

368288
stoichiometry: 1.0
species: 284145
type: SpeciesReference

351865
stoichiometry: 1.0
species: 284562
type: SpeciesReference

283236
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Phosphohydroxypyruvate_C3H2O7P
type: Species

293754
value: 0.0
type: LocalParameter

282873
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

283977
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

299413
value: 0.0
type: LocalParameter

373775
stoichiometry: 0.27
species: 285541
type: SpeciesReference

283824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Aspartyl_tRNA_Asp__C4H5NO3R
type: Species

285577
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

349834
stoichiometry: 1.0
species: 284624
type: SpeciesReference

396640
stoichiometry: 1.0
species: 286447
type: SpeciesReference

435296
stoichiometry: 1.0
species: 284589
type: SpeciesReference

383915
stoichiometry: 7.0
species: 285499
type: SpeciesReference

289546
kinetic law: 400748
product: 400736
reactant: 400724
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_all_trans_hexaprenyl_diphosphate_transport__mitochondrial
type: Reaction

380438
stoichiometry: 1.0
species: 286402
type: SpeciesReference

302029
value: 999999.0
type: LocalParameter

405448
stoichiometry: 1.0
species: 285086
type: SpeciesReference

300633
value: 0.0
type: LocalParameter

293753
value: 0.0
type: LocalParameter

284711
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Oxidized_glutathione_C20H30N6O12S2
type: Species

430855
stoichiometry: 1.0
species: 285982
type: SpeciesReference

371626
stoichiometry: 1.0
species: 284307
type: SpeciesReference

359831
stoichiometry: 1.0
species: 285757
type: SpeciesReference

404698
stoichiometry: 1.0
species: 283908
type: SpeciesReference

440697
stoichiometry: 1.0
species: 286462
type: SpeciesReference

380100
stoichiometry: 1.0
species: 286537
type: SpeciesReference

293340
value: 999999.0
type: LocalParameter

364947
stoichiometry: 2.0
species: 284808
type: SpeciesReference

289658
kinetic law: 404252
product: 404240
reactant: 404228
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_indole_3_acetate_mitochondrial_transport_via_diffusion
type: Reaction

300632
value: 0.0
type: LocalParameter

290504
name: R_ribonucleoside_triphosphate_reductase__CTP_
kinetic law: 431762
notes: GENE_ASSOCIATION: ( YGR209C or YLR043C ) PROTEIN_ASSOCIATION: ( Trx2 ) or ( Trx1 ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2
reversible: false
fast: false
reactant: 431714
product: 431726
type: Reaction
product: 431750
reactant: 431702
product: 431738

299411
value: 999999.0
type: LocalParameter

293542
value: 999999.0
type: LocalParameter

421210
stoichiometry: 1.0
species: 283626
type: SpeciesReference

374439
stoichiometry: 1.0
species: 286576
type: SpeciesReference

283347
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Phospho_L_aspartate_C4H6NO7P
type: Species

282871
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

348145
stoichiometry: 1.0
species: 283578
type: SpeciesReference

288623
kinetic law: 376044
product: 376032
reactant: 376020
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_episterol_exchange
type: Reaction

289544
kinetic law: 400712
product: 400700
reactant: 400688
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_fatty_acid_intracellular_transport
type: Reaction

384673
stoichiometry: 8.0
species: 284025
type: SpeciesReference

298460
value: 0.0
type: LocalParameter

395326
stoichiometry: 1.0
species: 285454
type: SpeciesReference

433383
stoichiometry: 1.0
species: 284787
type: SpeciesReference

283233
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_3_Phospho_D_glycerate_C3H4O7P
type: Species

442026
stoichiometry: 1.0
species: 283716
type: SpeciesReference

299410
value: -999999.0
type: LocalParameter

293969
value: 0.0
type: LocalParameter

434632
stoichiometry: 1.0
species: 286087
type: SpeciesReference

353599
stoichiometry: 1.0
species: 284796
type: SpeciesReference

298461
value: 10.0
type: LocalParameter

284609
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Glutamate_5_phosphate_C5H8NO7P
type: Species

285790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Propanoyl_CoA_C24H36N7O17P3S
type: Species

420580
stoichiometry: 1.0
species: 285029
type: SpeciesReference

284714
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Oxidized_glutathione_C20H30N6O12S2
type: Species

436736
stoichiometry: 1.0
species: 283512
type: SpeciesReference

289115
reactant: 385570
product: 385618
reactant: 385546
product: 385594
fast: false
kinetic law: 385642
name: R_fatty_acyl_ACP_synthase__n_C120ACP___mitochondrial
product: 385582
product: 385606
reversible: false
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
reactant: 385534
type: Reaction
product: 385630
reactant: 385558

292151
value: 0.033364
type: LocalParameter

299417
value: -999999.0
type: LocalParameter

298357
value: 0.0
type: LocalParameter

302025
value: 0.0038
type: LocalParameter

303761
value: 0.0
type: LocalParameter

289542
fast: false
product: 400651
reactant: 400615
name: R_hexokinase__D_fructoseATP_
reactant: 400627
kinetic law: 400676
type: Reaction
product: 400664
product: 400639
notes: GENE_ASSOCIATION: ( YFR053C or YGL253W ) PROTEIN_ASSOCIATION: ( Hxk1 ) or ( Hxk2 ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.1
reversible: false

290502
product: 431653
name: R_ribonucleoside_triphosphate_reductase__GTP_
product: 431666
product: 431678
kinetic law: 431690
reversible: false
fast: false
type: Reaction
notes: GENE_ASSOCIATION: ( YLR043C or YGR209C ) PROTEIN_ASSOCIATION: ( Trx1 ) or ( Trx2 ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2
reactant: 431629
reactant: 431641

362615
stoichiometry: 1.0
species: 285487
type: SpeciesReference

363567
stoichiometry: 1.0
species: 285436
type: SpeciesReference

289113
product: 385461
product: 385473
reversible: false
fast: false
reactant: 385413
product: 385509
reactant: 385425
type: Reaction
product: 385497
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reactant: 385449
kinetic law: 385522
name: R_fatty_acid_synthase__n_C120_
product: 385485
reactant: 385437

299416
value: 0.0
type: LocalParameter

292047
value: 999999.0
type: LocalParameter

285050
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indolepyruvate_C11H8NO3
type: Species

283827
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Allo_threonine_C4H9NO3
type: Species

293963
value: 0.0
type: LocalParameter

352682
stoichiometry: 1.0
species: 286027
type: SpeciesReference

423380
stoichiometry: 1.0
species: 284799
type: SpeciesReference

298358
value: 0.0
type: LocalParameter

353272
stoichiometry: 1.0
species: 283830
type: SpeciesReference

294805
value: 3.700069
type: LocalParameter

419191
stoichiometry: 1.0
species: 283641
type: SpeciesReference

298463
value: 0.0
type: LocalParameter

288620
kinetic law: 376008
product: 375996
reactant: 375984
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Deoxyuridine_exchange
type: Reaction

301588
value: 0.0
type: LocalParameter

285793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Prephenate_C10H8O6
type: Species

301587
value: 0.0
type: LocalParameter

293966
value: 999999.0
type: LocalParameter

292153
value: 0.0
type: LocalParameter

285053
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_myo_Inositol_C6H12O6
type: Species

294802
value: 0.0
type: LocalParameter

298359
value: 999999.0
type: LocalParameter

289540
fast: false
reactant: 400543
kinetic law: 400603
product: 400579
name: R_hexokinase__D_mannoseATP_
reversible: false
notes: GENE_ASSOCIATION: ( YFR053C or YGL253W ) PROTEIN_ASSOCIATION: ( Hxk1 ) or ( Hxk2 ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.7
type: Reaction
reactant: 400555
product: 400567
product: 400591

357618
stoichiometry: 1.0
species: 283782
type: SpeciesReference

290500
reactant: 431557
product: 431581
fast: false
name: R_ribonucleoside_triphosphate_reductase__ATP_
kinetic law: 431617
product: 431605
notes: GENE_ASSOCIATION: ( YLR043C or YGR209C ) PROTEIN_ASSOCIATION: ( Trx1 ) or ( Trx2 ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2
reactant: 431569
reversible: false
type: Reaction
product: 431593

283230
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_3_Oxotetradecanoyl_CoA_C35H56N7O18P3S
type: Species

298464
value: -999999.0
type: LocalParameter

350484
stoichiometry: 1.0
species: 283497
type: SpeciesReference

302027
value: 0.0
type: LocalParameter

410507
stoichiometry: 1.0
species: 285267
type: SpeciesReference

356352
stoichiometry: 1.0
species: 284595
type: SpeciesReference

385947
stoichiometry: 1.0
species: 283419
type: SpeciesReference

289111
reversible: false
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86
name: R_fatty_acyl_CoA_synthase__n_C100CoA_
product: 385341
reactant: 385317
product: 385365
fast: false
reactant: 385329
product: 385353
kinetic law: 385401
reactant: 385304
type: Reaction
reactant: 385292
product: 385377
product: 385389

301589
value: -999999.0
type: LocalParameter

292154
value: 0.0
type: LocalParameter

385208
stoichiometry: 1.0
species: 285514
type: SpeciesReference

287140
name: R_3_Dehydrosphinganine_reductase
reactant: 345509
notes: GENE_ASSOCIATION: YBR265W PROTEIN_ASSOCIATION: Tsc10 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS: 1.1.1.102
fast: false
product: 345545
product: 345533
reactant: 345497
type: Reaction
reversible: false
kinetic law: 345557
reactant: 345521

293852
value: 0.0
type: LocalParameter

419312
stoichiometry: 1.0
species: 284790
type: SpeciesReference

284717
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Oxidized_glutathione_C20H30N6O12S2
type: Species

299414
value: 0.0
type: LocalParameter

293751
value: 0.0
type: LocalParameter

283974
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Citrulline_C6H13N3O3
type: Species

431931
stoichiometry: 1.0
species: 284618
type: SpeciesReference

419033
stoichiometry: 1.0
species: 283332
type: SpeciesReference

282876
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

345775
stoichiometry: 1.0
species: 283185
type: SpeciesReference

302026
value: 0.0
type: LocalParameter

303760
value: 999999.0
type: LocalParameter

292049
value: 0.0
type: LocalParameter

298465
value: 999999.0
type: LocalParameter

405302
stoichiometry: 0.01
species: 282893
type: SpeciesReference

345605
stoichiometry: 1.0
species: 284787
type: SpeciesReference

300939
value: 0.0
type: LocalParameter

293506
value: 0.0
type: LocalParameter

299532
value: 0.0
type: LocalParameter

292832
value: 999999.0
type: LocalParameter

293663
value: 999999.0
type: LocalParameter

299685
value: 0.0
type: LocalParameter

376783
stoichiometry: 1.0
species: 284621
type: SpeciesReference

291039
value: -999999.0
type: LocalParameter

433576
stoichiometry: 1.0
species: 283830
type: SpeciesReference

293809
value: 0.0
type: LocalParameter

299470
value: 0.0
type: LocalParameter

298390
value: 0.0
type: LocalParameter

440552
stoichiometry: 1.0
species: 284757
type: SpeciesReference

379278
stoichiometry: 1.0
species: 286975
type: SpeciesReference

297877
value: 0.0
type: LocalParameter

440447
stoichiometry: 1.0
species: 286453
type: SpeciesReference

283467
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M__S__Squalene_2_3_epoxide_C30H50O
type: Species

418587
stoichiometry: 1.0
species: 283521
type: SpeciesReference

360089
stoichiometry: 1.0
species: 283836
type: SpeciesReference

442147
stoichiometry: 1.0
species: 286498
type: SpeciesReference

290688
notes: GENE_ASSOCIATION: YLR209C PROTEIN_ASSOCIATION: Pnp1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.4
product: 437947
name: R_thymidine_phosphorylase
reversible: true
reactant: 437923
product: 437935
reactant: 437911
type: Reaction
kinetic law: 437959
fast: false

344239
stoichiometry: 1.0
species: 283008
type: SpeciesReference

300700
value: 999999.0
type: LocalParameter

289007
kinetic law: 380969
product: 380957
reactant: 380945
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport
type: Reaction

419493
stoichiometry: 1.0
species: 284796
type: SpeciesReference

291038
value: 0.0
type: LocalParameter

292295
value: 0.0
type: LocalParameter

284834
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Hexadecanoate__n_C160__C16H31O2
type: Species

436893
stoichiometry: 1.0
species: 285460
type: SpeciesReference

420460
stoichiometry: 1.0
species: 284787
type: SpeciesReference

299530
value: 999999.0
type: LocalParameter

301448
value: 999999.0
type: LocalParameter

299683
value: -0.085323
type: LocalParameter

348578
stoichiometry: 1.0
species: 283548
type: SpeciesReference

422621
stoichiometry: 1.0
species: 285751
type: SpeciesReference

298391
value: 999999.0
type: LocalParameter

289778
reactant: 408458
reactant: 408446
type: Reaction
product: 408470
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
reversible: true
product: 408482
name: R_L_lactate_transport__mitochondrial
kinetic law: 408494

297876
value: 999999.0
type: LocalParameter

293504
value: 0.0
type: LocalParameter

300703
value: 0.0
type: LocalParameter

284831
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Hexadecanoate__n_C160__C16H31O2
type: Species

357149
stoichiometry: 1.0
species: 283713
type: SpeciesReference

290570
kinetic law: 433894
product: 433882
reactant: 433870
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: false
name: R_sphinganine_1_phosphate_endoplasmic_reticular_transport
type: Reaction

386707
stoichiometry: 1.0
species: 284013
type: SpeciesReference

292830
value: 0.0
type: LocalParameter

299687
value: 0.0
type: LocalParameter

372376
stoichiometry: 1.0
species: 284778
type: SpeciesReference

301444
value: 0.0
type: LocalParameter

404228
stoichiometry: 1.0
species: 285032
type: SpeciesReference

349954
stoichiometry: 1.0
species: 284766
type: SpeciesReference

437451
stoichiometry: 1.0
species: 285454
type: SpeciesReference

432331
stoichiometry: 1.0
species: 285880
type: SpeciesReference

301445
value: 0.0
type: LocalParameter

293807
value: 999999.0
type: LocalParameter

288767
kinetic law: 377797
product: 377785
reactant: 377773
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Lanosterol_exchange
type: Reaction

435851
stoichiometry: 1.0
species: 286138
type: SpeciesReference

299472
value: -0.060582
type: LocalParameter

292291
value: 999999.0
type: LocalParameter

283905
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ceramide_1__Sphinganinen_C240__C42H85NO3
type: Species

297988
value: 999999.0
type: LocalParameter

289231
kinetic law: 390759
product: 390747
reactant: 390735
reactant: 390723
notes: GENE_ASSOCIATION: YPL262W PROTEIN_ASSOCIATION: Fum1 SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 4.2.1.2
fast: false
reversible: true
name: R_fumarase
type: Reaction

297875
value: 0.0
type: LocalParameter

388236
stoichiometry: 6.0
species: 285421
type: SpeciesReference

373063
stoichiometry: 0.01
species: 284340
type: SpeciesReference

351985
stoichiometry: 0.27
species: 285775
type: SpeciesReference

430139
stoichiometry: 1.0
species: 285943
type: SpeciesReference

294480
value: 0.0
type: LocalParameter

414509
stoichiometry: 1.0
species: 285751
type: SpeciesReference

292293
value: 0.0
type: LocalParameter

293660
value: 0.0
type: LocalParameter

350062
stoichiometry: 1.0
species: 283566
type: SpeciesReference

299533
value: 0.0
type: LocalParameter

359904
stoichiometry: 1.0
species: 283608
type: SpeciesReference

435212
stoichiometry: 1.0
species: 283608
type: SpeciesReference

293349
value: 999999.0
type: LocalParameter

352105
stoichiometry: 1.0
species: 285427
type: SpeciesReference

383999
stoichiometry: 7.0
species: 284025
type: SpeciesReference

297987
value: -999999.0
type: LocalParameter

297874
value: 0.0
type: LocalParameter

388981
stoichiometry: 0.02
species: 285775
type: SpeciesReference

300935
value: 0.0
type: LocalParameter

292298
value: 0.0
type: LocalParameter

284837
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Hexadecenoate__n_C161__C16H29O2
type: Species

303272
value: 0.0
type: LocalParameter

378831
stoichiometry: 1.0
species: 285784
type: SpeciesReference

299536
value: -999999.0
type: LocalParameter

290572
kinetic law: 433942
product: 433930
product: 433918
reactant: 433906
notes: GENE_ASSOCIATION: YDR294C PROTEIN_ASSOCIATION: Dpl1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
fast: false
reversible: false
name: R_sphinganine_phosphate_lyase
type: Reaction

430711
stoichiometry: 1.0
species: 284787
type: SpeciesReference

443668
stoichiometry: 1.0E-6
species: 286201
type: SpeciesReference

421670
stoichiometry: 1.0
species: 284544
type: SpeciesReference

429910
stoichiometry: 1.0
species: 285943
type: SpeciesReference

356498
stoichiometry: 1.0
species: 284757
type: SpeciesReference

298394
value: 0.0
type: LocalParameter

436470
stoichiometry: 1.0
species: 284787
type: SpeciesReference

299680
value: 999999.0
type: LocalParameter

289233
product: 390807
product: 390795
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 3.7.1.2
type: Reaction
reactant: 390771
product: 390819
name: R_fumarylacetoacetase
reversible: false
reactant: 390783
kinetic law: 390832
fast: false

288962
kinetic law: 380160
product: 380148
reactant: 380136
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_zymosterol_exchange
type: Reaction

425412
stoichiometry: 1.0
species: 284787
type: SpeciesReference

385329
stoichiometry: 1.0
species: 285517
type: SpeciesReference

300934
value: -0.138983
type: LocalParameter

301443
value: 0.0
type: LocalParameter

293804
value: 0.0
type: LocalParameter

435706
stoichiometry: 1.0
species: 284403
type: SpeciesReference

376638
stoichiometry: 1.0
species: 284547
type: SpeciesReference

299535
value: 0.0
type: LocalParameter

290684
reversible: false
product: 437789
product: 437801
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.1.21
fast: false
reactant: 437777
reactant: 437765
kinetic law: 437826
product: 437814
type: Reaction
name: R_thymidine_kinase__ATPthymidine_

419154
stoichiometry: 1.0
species: 283992
type: SpeciesReference

297872
value: 0.0
type: LocalParameter

293509
value: -999999.0
type: LocalParameter

428435
stoichiometry: 1.0
species: 283830
type: SpeciesReference

288764
kinetic law: 377761
product: 377749
reactant: 377737
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Lactate_exchange
type: Reaction

285670
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

301440
value: 0.0
type: LocalParameter

420315
stoichiometry: 1.0
species: 284787
type: SpeciesReference

293803
value: 0.0
type: LocalParameter

399961
stoichiometry: 1.0
species: 284799
type: SpeciesReference

284568
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_GDP_C10H12N5O11P2
type: Species

369972
stoichiometry: 1.0
species: 284229
type: SpeciesReference

430939
stoichiometry: 1.0
species: 284757
type: SpeciesReference

407928
stoichiometry: 1.0
species: 282971
type: SpeciesReference

290574
type: Reaction
product: 433978
reversible: false
kinetic law: 434014
product: 433990
reactant: 433954
reactant: 433966
fast: false
name: R_Spermidine_acetyltransferase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.3.1.57
product: 434002

297871
value: 0.0
type: LocalParameter

293508
value: 0.0
type: LocalParameter

412090
stoichiometry: 0.01
species: 282893
type: SpeciesReference

352610
stoichiometry: 1.0
species: 284787
type: SpeciesReference

439628
stoichiometry: 1.0
species: 284787
type: SpeciesReference

299682
value: 0.0
type: LocalParameter

381694
stoichiometry: 1.0
species: 284778
type: SpeciesReference

380716
stoichiometry: 1.0
species: 286156
type: SpeciesReference

289235
kinetic law: 390881
product: 390869
reactant: 390857
reactant: 390845
notes: GENE_ASSOCIATION: YPL262W PROTEIN_ASSOCIATION: Fum1-m SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 4.2.1.2
fast: false
reversible: true
name: R_fumarase__mitochondrial
type: Reaction

299537
value: 999999.0
type: LocalParameter

288761
kinetic law: 377725
product: 377713
reactant: 377701
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_lactate_exchange
type: Reaction

292297
value: 0.0
type: LocalParameter

357029
stoichiometry: 1.0
species: 283830
type: SpeciesReference

303271
value: 0.0
type: LocalParameter

302169
value: 0.0
type: LocalParameter

300936
value: 999999.0
type: LocalParameter

411460
stoichiometry: 1.0
species: 285053
type: SpeciesReference

434777
stoichiometry: 1.0
species: 285436
type: SpeciesReference

290686
reversible: false
product: 437887
product: 437862
reactant: 437838
notes: GENE_ASSOCIATION: YOR143C PROTEIN_ASSOCIATION: Thi80 SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.7.6.2
fast: false
name: R_thiamine_diphosphokinase
product: 437875
reactant: 437850
type: Reaction
kinetic law: 437899

298393
value: 0.0
type: LocalParameter

346694
stoichiometry: 1.0
species: 285748
type: SpeciesReference

283908
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_1__Sphinganinen_C260__C44H89NO3
type: Species

400240
stoichiometry: 1.0
species: 284864
type: SpeciesReference

362868
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298160
value: 0.0
type: LocalParameter

383128
stoichiometry: 1.0
species: 285550
type: SpeciesReference

297982
value: 999999.0
type: LocalParameter

419264
stoichiometry: 1.0
species: 284624
type: SpeciesReference

290576
type: Reaction
product: 434050
product: 434062
kinetic law: 434074
name: R_spermidine_transport_in_via_proton_antiport
reactant: 434038
notes: GENE_ASSOCIATION: ( YOR273C or YLL028W ) PROTEIN_ASSOCIATION: ( Tpo4 ) or ( Tpo1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
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fast: false
reversible: false

421561
stoichiometry: 1.0
species: 286132
type: SpeciesReference

289770
reversible: true
type: Reaction
kinetic law: 408254
name: R_L_lysine_reversible_transport_via_proton_symport
product: 408242
fast: false
reactant: 408205
notes: GENE_ASSOCIATION: ( YNL268W or YKR039W ) PROTEIN_ASSOCIATION: ( Lyp1 ) or ( Gap1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reactant: 408218
product: 408230

385437
stoichiometry: 1.0
species: 285219
type: SpeciesReference

300709
value: 999999.0
type: LocalParameter

378988
stoichiometry: 1.0
species: 286951
type: SpeciesReference

400760
stoichiometry: 1.0
species: 284891
type: SpeciesReference

300931
value: 0.0
type: LocalParameter

430602
stoichiometry: 1.0
species: 285751
type: SpeciesReference

289341
kinetic law: 394311
product: 394299
reactant: 394286
reactant: 394274
notes: GENE_ASSOCIATION: YIL099W PROTEIN_ASSOCIATION: Sga1-v SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.3
fast: false
reversible: false
name: R_glucan_1_4_alpha_glucosidase__vacuole
type: Reaction

425304
stoichiometry: 1.0
species: 284796
type: SpeciesReference

301335
value: 0.0
type: LocalParameter

288247
name: R_dihydrofolate_reductase__mitochondrial
type: Reaction
product: 369387
reactant: 369375
reversible: false
reactant: 369363
product: 369399
fast: false
notes: GENE_ASSOCIATION: YOR236W PROTEIN_ASSOCIATION: Dfr1-m SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 1.5.1.3
reactant: 369350
kinetic law: 369411

357474
stoichiometry: 1.0
species: 284897
type: SpeciesReference

302167
value: 999999.0
type: LocalParameter

345836
stoichiometry: 1.0
species: 283065
type: SpeciesReference

372486
stoichiometry: 1.0
species: 284151
type: SpeciesReference

348009
stoichiometry: 1.0
species: 283218
type: SpeciesReference

290680
notes: GENE_ASSOCIATION: ( YBR117C or YPR074C ) PROTEIN_ASSOCIATION: ( Tkl2 ) or ( Tkl1 ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 2.2.1.1
type: Reaction
reversible: true
reactant: 437645
fast: false
kinetic law: 437693
product: 437681
name: R_transketolase
reactant: 437657
product: 437669

300708
value: 0.0
type: LocalParameter

300930
value: 0.0
type: LocalParameter

287394
reactant: 350340
fast: false
reactant: 350352
product: 350376
type: Reaction
notes: GENE_ASSOCIATION: YCR032W PROTEIN_ASSOCIATION: Bph1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
kinetic law: 350388
reversible: true
product: 350364
name: R_acetate_reversible_transport_via_proton_symport

414872
stoichiometry: 1.0
species: 285387
type: SpeciesReference

353345
stoichiometry: 1.0
species: 283662
type: SpeciesReference

427186
stoichiometry: 0.01
species: 285865
type: SpeciesReference

297980
value: 0.0
type: LocalParameter

427658
stoichiometry: 1.0
species: 285883
type: SpeciesReference

290578
kinetic law: 434111
product: 434099
reactant: 434086
notes: GENE_ASSOCIATION: YKL174C PROTEIN_ASSOCIATION: Tpo5-g SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_spermidine_excretion__cytosol_to_extracellular_
type: Reaction

289772
type: Reaction
product: 408290
name: R_L_lysine_transport_in_via_proton_antiport__vacuolar_
fast: false
product: 408302
notes: GENE_ASSOCIATION: ( YBR293W or YCL069W or YMR088C ) PROTEIN_ASSOCIATION: ( Vba2-v ) or ( Vba3-v ) or ( Vba1-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
reversible: false
kinetic law: 408314
reactant: 408266
reactant: 408278

302166
value: 0.0
type: LocalParameter

431509
stoichiometry: 1.0
species: 283602
type: SpeciesReference

289345
kinetic law: 394401
product: 394387
reactant: 394374
reactant: 394361
notes: GENE_ASSOCIATION: YPR160W PROTEIN_ASSOCIATION: Gph1 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.1
fast: false
reversible: false
name: R_glycogen_phosphorylase
type: Reaction

437415
stoichiometry: 1.0
species: 283497
type: SpeciesReference

301331
value: 999999.0
type: LocalParameter

293959
value: 0.0
type: LocalParameter

426280
stoichiometry: 1.0
species: 285826
type: SpeciesReference

346585
stoichiometry: 1.0
species: 285399
type: SpeciesReference

289343
kinetic law: 394348
product: 394336
reactant: 394324
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
fast: false
reversible: false
name: R_Glycogen_vacuolar__transport__via_autophagy
type: Reaction

288244
reversible: false
type: Reaction
fast: false
product: 369314
reactant: 369290
notes: GENE_ASSOCIATION: YOR236W PROTEIN_ASSOCIATION: Dfr1 SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 1.5.1.3
reactant: 369278
kinetic law: 369338
name: R_dihydrofolate_reductase__irreversible_
reactant: 369302
product: 369326

283461
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_S_Formylglutathione_C11H16N3O7S
type: Species

302165
value: 0.0
type: LocalParameter

369862
stoichiometry: 1.0
species: 283872
type: SpeciesReference

284565
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282876
name: M_GDP_C10H12N5O11P2
type: Species

284412
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

290682
fast: false
reversible: true
kinetic law: 437753
reactant: 437705
name: R_transketolase
notes: GENE_ASSOCIATION: ( YPR074C or YBR117C ) PROTEIN_ASSOCIATION: ( Tkl1 ) or ( Tkl2 ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 2.2.1.1
product: 437741
reactant: 437717
product: 437729
type: Reaction

282870
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

301332
value: 0.0
type: LocalParameter

393211
stoichiometry: 1.0
species: 285162
type: SpeciesReference

396230
stoichiometry: 1.0
species: 284648
type: SpeciesReference

297986
value: 0.0
type: LocalParameter

436785
stoichiometry: 1.0
species: 283512
type: SpeciesReference

298164
value: 999999.0
type: LocalParameter

284562
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_GDP_C10H12N5O11P2
type: Species

401625
stoichiometry: 1.0
species: 283476
type: SpeciesReference

406018
stoichiometry: 1.0
species: 285427
type: SpeciesReference

289117
product: 385753
reactant: 385691
product: 385716
reactant: 385654
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86
reactant: 385667
product: 385741
product: 385704
kinetic law: 385765
product: 385728
reactant: 385679
name: R_fatty_acyl_CoA_synthase__n_C120CoA_
reversible: false
fast: false
type: Reaction

299689
value: 999999.0
type: LocalParameter

293502
value: 999999.0
type: LocalParameter

374354
stoichiometry: 1.0
species: 283047
type: SpeciesReference

283464
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__S__Squalene_2_3_epoxide_C30H50O
type: Species

288473
kinetic law: 374234
product: 374222
reactant: 374210
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_ethanol_transport_to_mitochondria__diffusion_
type: Reaction

297203
value: -999999.0
type: LocalParameter

289560
reactant: 401205
reactant: 401217
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
product: 401241
type: Reaction
kinetic law: 401253
product: 401229
fast: false
reversible: true
name: R_histidine_mitochondrial_transport_via_proton_symport

379386
stoichiometry: 1.0
species: 286984
type: SpeciesReference

289774
name: R_L_Lactate_dehydrogenase__cytosolicmitochondrial
product: 408350
notes: GENE_ASSOCIATION: ( ( YML054C and YEL039C ) or ( YML054C and YJR048W ) ) PROTEIN_ASSOCIATION: ( Cyb2-m and Cyc7-m ) or ( Cyb2-m and Cyc1-m ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 1.1.2.3
reversible: false
fast: false
type: Reaction
reactant: 408326
kinetic law: 408374
reactant: 408338
product: 408362

371554
stoichiometry: 1.0
species: 284289
type: SpeciesReference

297985
value: 0.0
type: LocalParameter

376674
stoichiometry: 1.0
species: 284556
type: SpeciesReference

362988
stoichiometry: 1.0
species: 283914
type: SpeciesReference

348687
stoichiometry: 1.0
species: 284624
type: SpeciesReference

298165
value: 0.0
type: LocalParameter

419384
stoichiometry: 1.0
species: 285598
type: SpeciesReference

422020
stoichiometry: 0.01
species: 285712
type: SpeciesReference

433153
stoichiometry: 1.0
species: 285421
type: SpeciesReference

344348
stoichiometry: 1.0
species: 284787
type: SpeciesReference

300704
value: 0.0
type: LocalParameter

302163
value: 0.029362
type: LocalParameter

435936
stoichiometry: 1.0
species: 285769
type: SpeciesReference

417346
stoichiometry: 1.0
species: 284757
type: SpeciesReference

345715
stoichiometry: 1.0
species: 283626
type: SpeciesReference

442256
stoichiometry: 1.0
species: 285796
type: SpeciesReference

284418
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_1_6_bisphosphate_C6H10O12P2
type: Species

394033
stoichiometry: 1.0
species: 286036
type: SpeciesReference

357257
stoichiometry: 1.0
species: 285799
type: SpeciesReference

388345
stoichiometry: 2.0
species: 284757
type: SpeciesReference

301336
value: -0.001188
type: LocalParameter

298162
value: 0.0
type: LocalParameter

301449
value: 0.0
type: LocalParameter

297879
value: 0.0
type: LocalParameter

302162
value: 0.0
type: LocalParameter

289119
reactant: 385777
product: 385874
name: R_fatty_acid_synthase__n_C140_
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
fast: false
product: 385825
reactant: 385789
kinetic law: 385886
product: 385849
reversible: false
product: 385837
type: Reaction
reactant: 385813
product: 385862
reactant: 385801

300707
value: 0.0
type: LocalParameter

285071
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

287391
fast: false
product: 350316
reactant: 350268
kinetic law: 350328
reversible: false
product: 350304
type: Reaction
product: 350292
reactant: 350256
name: R_acetyl_CoA_synthetase
reactant: 350280
notes: GENE_ASSOCIATION: YAL054C PROTEIN_ASSOCIATION: Acs1-p SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 6.2.1.1

418431
stoichiometry: 1.0
species: 283974
type: SpeciesReference

369653
stoichiometry: 1.0
species: 284220
type: SpeciesReference

297201
value: -0.064146
type: LocalParameter

284415
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Formaldehyde_CH2O
type: Species

289562
fast: false
type: Reaction
kinetic law: 401313
product: 401289
name: R_L_histidine_reversible_transport_via_proton_symport
reversible: true
product: 401301
reactant: 401277
reactant: 401265
notes: GENE_ASSOCIATION: ( YGR191W or YKR039W or YCL025C or YBR069C ) PROTEIN_ASSOCIATION: ( Hip1 ) or ( Gap1 ) or ( Agp1 ) or ( Tat1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:

406789
stoichiometry: 1.0
species: 285396
type: SpeciesReference

289776
reversible: true
type: Reaction
fast: false
product: 408422
product: 408410
reactant: 408398
reactant: 408386
name: R_L_lactate_reversible_transport_via_proton_symport
kinetic law: 408434
notes: GENE_ASSOCIATION: YKL217W PROTEIN_ASSOCIATION: Jen1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:

297983
value: 0.0
type: LocalParameter

372799
stoichiometry: 1.0
species: 284322
type: SpeciesReference

301337
value: 0.0
type: LocalParameter

432487
stoichiometry: 1.0
species: 285409
type: SpeciesReference

428966
stoichiometry: 1.0
species: 285970
type: SpeciesReference

298163
value: -999999.0
type: LocalParameter

437561
stoichiometry: 1.0
species: 283335
type: SpeciesReference

422249
stoichiometry: 1.0
species: 285718
type: SpeciesReference

350171
stoichiometry: 1.0
species: 283503
type: SpeciesReference

386815
stoichiometry: 1.0
species: 286402
type: SpeciesReference

283308
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_hydroxybenoyl_CoA_C28H36N7O18P3S
type: Species

356775
stoichiometry: 1.0
species: 284787
type: SpeciesReference

288470
kinetic law: 374198
product: 374186
reactant: 374174
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_ethanol_reversible_transport
type: Reaction

443548
stoichiometry: 0.1339
species: 285718
type: SpeciesReference

368059
stoichiometry: 1.0
species: 284787
type: SpeciesReference

391713
stoichiometry: 1.0
species: 284787
type: SpeciesReference

288464
product: 374112
reactant: 374063
reactant: 374075
kinetic law: 374124
fast: false
product: 374088
name: R_Ethanolaminephosphotransferase__yeast_specific
product: 374100
notes: GENE_ASSOCIATION: YHR123W PROTEIN_ASSOCIATION: Ept1 SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 2.7.8.1
type: Reaction
reversible: true

419045
stoichiometry: 1.0
species: 284001
type: SpeciesReference

294591
value: 999999.0
type: LocalParameter

421959
stoichiometry: 1.0
species: 284502
type: SpeciesReference

297206
value: 0.0
type: LocalParameter

288250
fast: false
product: 369497
kinetic law: 369509
reversible: false
type: Reaction
product: 369484
reactant: 369435
name: R_dihydrofolate_synthase
reactant: 369423
product: 369459
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 6.3.2.12
product: 369471
reactant: 369447

284999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Indole_3_acetaldehyde_C10H9NO
type: Species

293953
value: 999999.0
type: LocalParameter

301552
value: 0.0
type: LocalParameter

283314
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_trans_4_Hydroxy_L_proline_C5H9NO3
type: Species

287176
kinetic law: 346114
product: 346102
reactant: 346090
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_Octaprenyl_4_hydroxybenzoate_mitochondrial_transport
type: Reaction

292142
value: 0.028496
type: LocalParameter

288542
kinetic law: 375067
product: 375055
reactant: 375043
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Alanine_exchange
type: Reaction

289123
reactant: 386045
reactant: 386058
reactant: 386032
reversible: false
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86
type: Reaction
product: 386082
fast: false
product: 386094
product: 386106
product: 386118
name: R_fatty_acyl_CoA_synthase__n_C140CoA_
reactant: 386020
product: 386070
kinetic law: 386130

356340
stoichiometry: 1.0
species: 283959
type: SpeciesReference

383274
stoichiometry: 1.0
species: 283845
type: SpeciesReference

290794
product: 441240
name: R_urea_carboxylase
reactant: 441228
kinetic law: 441288
notes: GENE_ASSOCIATION: YBR208C PROTEIN_ASSOCIATION: Dur1 SUBSYSTEM: S_Nitrogen_Metabolism PROTEIN_CLASS: 6.3.4.6
reactant: 441204
reversible: true
product: 441276
fast: false
product: 441264
product: 441252
reactant: 441216
type: Reaction

284409
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

414956
stoichiometry: 1.0
species: 285856
type: SpeciesReference

363265
stoichiometry: 1.0
species: 284787
type: SpeciesReference

289552
reactant: 400904
fast: false
kinetic law: 400964
reactant: 400916
type: Reaction
notes: GENE_ASSOCIATION: YCL030C PROTEIN_ASSOCIATION: His4 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 1.1.1.23
reactant: 400892
product: 400940
name: R_histidinol_dehydrogenase
reversible: false
product: 400952
product: 400928

302015
value: 999999.0
type: LocalParameter

285523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

297207
value: 0.0
type: LocalParameter

301551
value: 0.0
type: LocalParameter

302172
value: 0.0
type: LocalParameter

390131
stoichiometry: 1.0
species: 285083
type: SpeciesReference

298157
value: 999999.0
type: LocalParameter

285065
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

289339
kinetic law: 394262
product: 394250
reactant: 394238
reactant: 394226
notes: GENE_ASSOCIATION: YPR184W PROTEIN_ASSOCIATION: Gdb1 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.3
fast: false
reversible: false
name: R_glucan_1_4_alpha_glucosidase
type: Reaction

289125
reactant: 386179
product: 386251
product: 386203
fast: false
type: Reaction
product: 386227
kinetic law: 386263
reactant: 386191
reactant: 386155
reactant: 386167
reversible: false
name: R_fatty_acid_synthase__n_C141_
notes: GENE_ASSOCIATION: YJL196C PROTEIN_ASSOCIATION: Elo1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
product: 386239
product: 386215
reactant: 386142

298095
value: 0.0
type: LocalParameter

348723
stoichiometry: 1.0
species: 284796
type: SpeciesReference

302012
value: 0.0
type: LocalParameter

405062
stoichiometry: 0.01
species: 282893
type: SpeciesReference

285062
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Inosine_C10H12N4O5
type: Species

367177
stoichiometry: 1.0
species: 283983
type: SpeciesReference

292140
value: 0.0
type: LocalParameter

298156
value: 0.0
type: LocalParameter

285520
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

293951
value: 0.0
type: LocalParameter

287833
notes: GENE_ASSOCIATION: YPR128C PROTEIN_ASSOCIATION: Ant1-p SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
reversible: false
product: 360185
product: 360197
reactant: 360161
product: 360210
kinetic law: 360222
name: R_ADPATP_transporter__peroxisomal
reactant: 360149
type: Reaction
reactant: 360173
fast: false

295189
value: 999999.0
type: LocalParameter

293248
value: 999999.0
type: LocalParameter

414653
stoichiometry: 1.0
species: 285454
type: SpeciesReference

366441
stoichiometry: 1.0
species: 284781
type: SpeciesReference

298155
value: 0.0
type: LocalParameter

346367
stoichiometry: 1.0
species: 284766
type: SpeciesReference

363555
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298094
value: 0.0
type: LocalParameter

287179
kinetic law: 346151
product: 346139
reactant: 346126
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_aminobutanal_mitochondrial_transport_via_diffusion
type: Reaction

352958
stoichiometry: 1.0
species: 283653
type: SpeciesReference

351113
stoichiometry: 1.0
species: 284735
type: SpeciesReference

294594
value: 0.0
type: LocalParameter

287728
reactant: 357690
kinetic law: 357726
product: 357714
reactant: 357678
reversible: false
type: Reaction
fast: false
notes: GENE_ASSOCIATION: ( YLR160C or YLR158C or YLR157C or YLR155C ) PROTEIN_ASSOCIATION: ( Asp34-e ) or ( Asp33-e ) or ( Asp32-e ) or ( Asp31-e ) SUBSYSTEM: S_Asparagine_metabolism PROTEIN_CLASS: 3.5.1.1
name: R_L_asparaginase__extracellular
product: 357702

289554
product: 401000
product: 401012
fast: false
reactant: 400976
kinetic law: 401024
reactant: 400988
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: YFR025C PROTEIN_ASSOCIATION: His2 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 3.1.3.15
name: R_histidinol_phosphatase

302013
value: 0.0
type: LocalParameter

297205
value: 999999.0
type: LocalParameter

284996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Indole_3_acetaldehyde_C10H9NO
type: Species

344604
stoichiometry: 1.0
species: 283023
type: SpeciesReference

375886
stoichiometry: 1.0
species: 286696
type: SpeciesReference

390468
stoichiometry: 1.0
species: 283830
type: SpeciesReference

290796
reactant: 441300
product: 441324
name: R_uridylate_kinase__dUMP_
reactant: 441312
reversible: true
kinetic law: 441348
product: 441336
fast: false
type: Reaction
notes: GENE_ASSOCIATION: YKL024C PROTEIN_ASSOCIATION: Ura6 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS:

289127
reactant: 386323
reversible: false
reactant: 386299
product: 386371
product: 386335
reactant: 386287
type: Reaction
product: 386359
fast: false
kinetic law: 386395
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
reactant: 386311
name: R_fatty_acyl_ACP_synthase__n_C141ACP___mitochondrial
product: 386383
product: 386347
reactant: 386275

283317
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_trans_4_Hydroxy_L_proline_C5H9NO3
type: Species

302170
value: 0.038545
type: LocalParameter

293952
value: -999999.0
type: LocalParameter

375959
stoichiometry: 1.0
species: 286702
type: SpeciesReference

298154
value: 0.0
type: LocalParameter

288319
type: Reaction
product: 370852
kinetic law: 370888
reversible: false
name: R_dephospho_CoA_kinase
reactant: 370828
fast: false
reactant: 370840
product: 370864
product: 370876
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.7.1.24

366658
stoichiometry: 1.0
species: 284778
type: SpeciesReference

409689
stoichiometry: 1.0
species: 285418
type: SpeciesReference

373859
stoichiometry: 1.0
species: 286438
type: SpeciesReference

442038
stoichiometry: 1.0
species: 285799
type: SpeciesReference

289556
reactant: 401037
product: 401097
notes: GENE_ASSOCIATION: YPR033C PROTEIN_ASSOCIATION: Hts1 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.21
kinetic law: 401109
product: 401073
type: Reaction
reversible: false
product: 401085
name: R_Histidyl_tRNA_synthetase
reactant: 401061
reactant: 401049
fast: false

293246
value: 0.0
type: LocalParameter

302019
value: 0.0
type: LocalParameter

388128
stoichiometry: 1.0
species: 285514
type: SpeciesReference

443440
stoichiometry: 0.1927
species: 285008
type: SpeciesReference

298092
value: 999999.0
type: LocalParameter

288316
kinetic law: 370816
product: 370792
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reactant: 370780
reversible: true
reactant: 370768
product: 370804
type: Reaction
name: R_dolichol_phosphate_endoplasmic_reticular_transport_via_proton_symport

293351
value: 0.0
type: LocalParameter

395314
stoichiometry: 1.0
species: 285409
type: SpeciesReference

289333
reversible: true
fast: false
name: R_glycine_hydroxymethyltransferase__reversible__mitochondrial
product: 394070
product: 394082
kinetic law: 394094
reactant: 394046
type: Reaction
product: 394058
notes: GENE_ASSOCIATION: YBR263W PROTEIN_ASSOCIATION: Shm1-m SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.1.2.1
reactant: 394033

301557
value: 0.0
type: LocalParameter

294302
value: 0.0
type: LocalParameter

380606
stoichiometry: 1.0
species: 286408
type: SpeciesReference

287385
kinetic law: 350159
type: Reaction
reactant: 350111
fast: false
reversible: false
product: 350147
product: 350123
name: R_acetyl_CoA_synthetase
notes: GENE_ASSOCIATION: YLR153C PROTEIN_ASSOCIATION: Acs2 SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 6.2.1.1
reactant: 350087
product: 350135
reactant: 350099

289335
reversible: true
fast: false
product: 394142
reactant: 394118
name: R_guanylate_kinase__GMPATP_
notes: GENE_ASSOCIATION: YDR454C PROTEIN_ASSOCIATION: Guk1.1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.4.8
kinetic law: 394154
product: 394130
reactant: 394106
type: Reaction

283311
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_4_Hydroxyglutamate_semialdehyde_C5H9NO4
type: Species

290798
reversible: true
fast: false
product: 441384
notes: GENE_ASSOCIATION: YKL024C PROTEIN_ASSOCIATION: Ura6-n SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS:
kinetic law: 441408
product: 441396
reactant: 441360
reactant: 441372
type: Reaction
name: R_uridylate_kinase__dUMP___nuclear

357871
stoichiometry: 1.0
species: 283830
type: SpeciesReference

422509
stoichiometry: 1.0
species: 285718
type: SpeciesReference

440661
stoichiometry: 1.0
species: 286438
type: SpeciesReference

364935
stoichiometry: 1.0
species: 284778
type: SpeciesReference

404686
stoichiometry: 0.01
species: 285068
type: SpeciesReference

374571
stoichiometry: 1.0
species: 283203
type: SpeciesReference

298091
value: -999999.0
type: LocalParameter

288256
product: 369593
notes: GENE_ASSOCIATION: YNL256W PROTEIN_ASSOCIATION: Fol1-m SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 4.1.2.25
reactant: 369557
product: 369581
type: Reaction
fast: false
reversible: false
product: 369569
name: R_dihydroneopterin_aldolase
kinetic law: 369605

301669
value: 0.0
type: LocalParameter

301556
value: 999999.0
type: LocalParameter

294301
value: -0.039794
type: LocalParameter

418864
stoichiometry: 1.0
species: 285727
type: SpeciesReference

299311
value: 0.0
type: LocalParameter

429365
stoichiometry: 1.0
species: 285928
type: SpeciesReference

302016
value: 0.0
type: LocalParameter

284993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Indole_3_acetaldehyde_C10H9NO
type: Species

443766
stoichiometry: 0.0015
species: 286549
type: SpeciesReference

291040
value: 999999.0
type: LocalParameter

289558
reactant: 401121
product: 401157
reversible: false
type: Reaction
fast: false
notes: GENE_ASSOCIATION: YPR033C PROTEIN_ASSOCIATION: Hts1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.21
kinetic law: 401193
product: 401181
reactant: 401133
product: 401169
reactant: 401145
name: R_histidyl_tRNA_synthetase__mitochondrial

298090
value: 0.0
type: LocalParameter

413575
stoichiometry: 1.0
species: 285273
type: SpeciesReference

288467
kinetic law: 374161
product: 374149
reactant: 374137
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_ethanolamine_transport_via_diffusion__extracellular_
type: Reaction

410787
stoichiometry: 1.0
species: 286489
type: SpeciesReference

406680
stoichiometry: 0.03
species: 285532
type: SpeciesReference

407237
stoichiometry: 1.0
species: 285140
type: SpeciesReference

301668
value: 8.92488
type: LocalParameter

289121
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
reactant: 385899
kinetic law: 386008
type: Reaction
reversible: false
product: 385947
product: 385984
product: 385959
fast: false
reactant: 385911
reactant: 385923
name: R_fatty_acyl_ACP_synthase__n_C140ACP___mitochondrial
product: 385996
product: 385971
reactant: 385935

396652
stoichiometry: 1.0
species: 282908
type: SpeciesReference

401409
stoichiometry: 1.0
species: 283155
type: SpeciesReference

293956
value: 0.0
type: LocalParameter

414327
stoichiometry: 1.0
species: 284757
type: SpeciesReference

298159
value: 0.0
type: LocalParameter

369435
stoichiometry: 1.0
species: 284226
type: SpeciesReference

299312
value: -999999.0
type: LocalParameter

289337
kinetic law: 394214
reversible: true
name: R_guanylate_kinase__GMPdATP_
fast: false
reactant: 394178
product: 394202
product: 394190
reactant: 394166
type: Reaction
notes: GENE_ASSOCIATION: YDR454C PROTEIN_ASSOCIATION: Guk1.1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.4.8

301553
value: 0.0
type: LocalParameter

410892
stoichiometry: 1.0
species: 284787
type: SpeciesReference

297209
value: 0.0
type: LocalParameter

287173
kinetic law: 346078
product: 346066
reactant: 346054
reactant: 346042
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
fast: false
reversible: false
name: R_3_Hexaprenyl_4_5_dihydroxybenzoate_hydroxylase__mitochondrial
type: Reaction

289780
kinetic law: 408530
product: 408518
reactant: 408506
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 5.2.1.2
fast: false
reversible: false
name: R_maleylacetoacetate_isomerase
type: Reaction

368276
stoichiometry: 1.0
species: 284790
type: SpeciesReference

291041
value: 0.0
type: LocalParameter

390347
stoichiometry: 1.0
species: 285273
type: SpeciesReference

288253
kinetic law: 369545
product: 369533
reactant: 369521
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_dihydrofolate_reversible_mitochondrial_transport
type: Reaction

294597
value: 0.0
type: LocalParameter

302018
value: 0.001727
type: LocalParameter

428533
stoichiometry: 1.0
species: 285643
type: SpeciesReference

293245
value: 0.0
type: LocalParameter

287388
type: Reaction
product: 350232
name: R_acetyl_CoA_synthetase
reversible: false
product: 350220
reactant: 350183
notes: GENE_ASSOCIATION: YAL054C PROTEIN_ASSOCIATION: Acs1-m SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 6.2.1.1
fast: false
reactant: 350196
reactant: 350171
kinetic law: 350244
product: 350208

364342
stoichiometry: 1.0
species: 283971
type: SpeciesReference

285068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

415731
stoichiometry: 1.0
species: 283830
type: SpeciesReference

287830
reactant: 360064
product: 360101
name: R_ADPATP_transporter__mitochondrial
kinetic law: 360137
product: 360125
reactant: 360089
reactant: 360077
type: Reaction
product: 360113
reversible: false
notes: GENE_ASSOCIATION: ( YBR085W or YBL030C or YMR056C ) PROTEIN_ASSOCIATION: ( Aac3-m ) or ( Pet9-m ) or ( Aac1-m ) SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false

289010
name: R_fatty_acyl_CoA_peroxisomal_transport_via_ABC_system
product: 381054
reversible: false
reactant: 380981
type: Reaction
reactant: 381005
fast: false
product: 381042
kinetic law: 381067
reactant: 380993
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
product: 381017
product: 381030

293355
value: 0.0
type: LocalParameter

287839
notes: GENE_ASSOCIATION: YOL064C PROTEIN_ASSOCIATION: Met22 SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 3.1.3.7
reactant: 360319
name: R_3__5__bisphosphate_nucleotidase
reversible: false
product: 360343
type: Reaction
fast: false
kinetic law: 360355
product: 360331
reactant: 360307

294487
value: 999999.0
type: LocalParameter

303265
value: 0.0
type: LocalParameter

299539
value: 0.0
type: LocalParameter

298388
value: 0.0
type: LocalParameter

299466
value: 0.0
type: LocalParameter

299313
value: 999999.0
type: LocalParameter

355544
stoichiometry: 1.0
species: 286477
type: SpeciesReference

289225
reversible: false
product: 390492
name: R_5_Formyltetrahydrofolate10_Formyltetrahydrofolate_isomerase
type: Reaction
fast: false
reactant: 390480
product: 390528
product: 390504
product: 390516
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS:
kinetic law: 390540
reactant: 390456
reactant: 390468

351769
stoichiometry: 1.0
species: 282953
type: SpeciesReference

366767
stoichiometry: 1.0
species: 284070
type: SpeciesReference

301665
value: 0.0
type: LocalParameter

400300
stoichiometry: 1.0
species: 285399
type: SpeciesReference

293356
value: 0.0
type: LocalParameter

293243
value: 4.455985
type: LocalParameter

288313
name: R_Dolichyl_phosphate_D_mannosyltransferase
type: Reaction
product: 370744
reactant: 370708
kinetic law: 370756
product: 370732
notes: GENE_ASSOCIATION: YPR183W PROTEIN_ASSOCIATION: Dpm1 SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS: 2.4.1.83
reactant: 370720
fast: false
reversible: false

298386
value: 0.0
type: LocalParameter

395422
stoichiometry: 1.0
species: 285421
type: SpeciesReference

404795
stoichiometry: 1.0
species: 285309
type: SpeciesReference

284990
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Isocitrate_C6H5O7
type: Species

291196
value: 999999.0
type: LocalParameter

303264
value: 0.0
type: LocalParameter

291043
value: 0.055472
type: LocalParameter

293659
value: 0.0
type: LocalParameter

292149
value: 0.0
type: LocalParameter

299467
value: 999999.0
type: LocalParameter

285676
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Pyridoxine_5__phosphate_C8H10NO6P
type: Species

301664
value: 999999.0
type: LocalParameter

375658
stoichiometry: 1.0
species: 284076
type: SpeciesReference

293801
value: 0.0
type: LocalParameter

288695
kinetic law: 376919
product: 376907
reactant: 376895
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Glycerol_exchange
type: Reaction

292839
value: -999999.0
type: LocalParameter

288548
kinetic law: 375139
product: 375127
reactant: 375115
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Allantoate_exchange
type: Reaction

289012
kinetic law: 381103
product: 381091
reactant: 381079
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport
type: Reaction

288965
kinetic law: 380196
product: 380184
reactant: 380172
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_zymosterol_ester__yeast_specific_exchange
type: Reaction

396543
stoichiometry: 1.0
species: 284678
type: SpeciesReference

298385
value: 999999.0
type: LocalParameter

293353
value: 6.33E-4
type: LocalParameter

357714
stoichiometry: 1.0
species: 285457
type: SpeciesReference

414727
stoichiometry: 1.0
species: 283839
type: SpeciesReference

299315
value: 0.0
type: LocalParameter

282971
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Aminomalonate_semialdehyde_C3H5NO3
type: Species

285673
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
type: Species

288692
kinetic law: 376882
product: 376870
reactant: 376858
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Glycine_exchange
type: Reaction

289227
type: Reaction
notes: GENE_ASSOCIATION: YGR204W PROTEIN_ASSOCIATION: Ade3 SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 6.3.4.3
reversible: false
fast: false
kinetic law: 390626
reactant: 390565
product: 390614
product: 390602
product: 390590
name: R_formate_tetrahydrofolate_ligase
reactant: 390553
reactant: 390577

287170
kinetic law: 346030
product: 346018
reactant: 346006
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_Methyl_2_oxopentanoate_transport__diffusion__mitochondrial
type: Reaction

384396
stoichiometry: 8.0
species: 284778
type: SpeciesReference

299690
value: 0.0
type: LocalParameter

292838
value: 0.0
type: LocalParameter

435633
stoichiometry: 0.09
species: 285550
type: SpeciesReference

358402
stoichiometry: 1.0
species: 283800
type: SpeciesReference

293241
value: 0.0
type: LocalParameter

394387
stoichiometry: 1.0
species: 284502
type: SpeciesReference

357366
stoichiometry: 1.0
species: 283761
type: SpeciesReference

380510
stoichiometry: 1.0
species: 283845
type: SpeciesReference

298384
value: -999999.0
type: LocalParameter

379494
stoichiometry: 1.0
species: 286993
type: SpeciesReference

291045
value: 0.0
type: LocalParameter

291198
value: 0.0
type: LocalParameter

292147
value: 999999.0
type: LocalParameter

288310
product: 370671
kinetic law: 370696
fast: false
name: R_Dolichyl_phosphate_mannose__protein_mannosyltransferase__endoplasmic_reticular
product: 370684
notes: GENE_ASSOCIATION: ( ( YDL095W and YAL023C ) or YOR321W or YJR143C or YDL093W or YGR199W ) PROTEIN_ASSOCIATION: ( Pmt1-er and Pmt2-er ) or ( Pmt3-er ) or ( Pmt4-er ) or ( Pmt5-er ) or ( Pmt6-er ) SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS: 2.4.1.109
reactant: 370647
reversible: false
product: 370659
type: Reaction

285529
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octadecanoate__n_C180__C18H35O2
type: Species

293657
value: 0.0
type: LocalParameter

414218
stoichiometry: 1.0
species: 284787
type: SpeciesReference

303262
value: 999999.0
type: LocalParameter

299316
value: 0.0
type: LocalParameter

299469
value: 0.0
type: LocalParameter

384204
stoichiometry: 7.0
species: 284808
type: SpeciesReference

294483
value: 0.0
type: LocalParameter

352730
stoichiometry: 1.0
species: 284208
type: SpeciesReference

384940
stoichiometry: 3.0
species: 284778
type: SpeciesReference

287722
kinetic law: 357606
reactant: 357534
product: 357594
fast: false
product: 357570
reactant: 357558
product: 357582
reactant: 357546
reversible: false
notes: GENE_ASSOCIATION: YDR158W PROTEIN_ASSOCIATION: Hom2 SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 1.2.1.11
name: R_aspartate_semialdehyde_dehydrogenase__irreversible
type: Reaction

283902
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_1__Sphinganinen_C240__C42H85NO3
type: Species

295182
value: 0.0038
type: LocalParameter

421802
stoichiometry: 1.0
species: 283233
type: SpeciesReference

403125
stoichiometry: 1.0
species: 285427
type: SpeciesReference

390023
stoichiometry: 1.0
species: 286105
type: SpeciesReference

301661
value: 0.0
type: LocalParameter

289015
name: R_fatty_acyl_ACP_hydrolase
product: 381163
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 3.1.2.14
fast: false
reactant: 381115
kinetic law: 381175
product: 381139
type: Reaction
product: 381151
reversible: true
reactant: 381127

403829
stoichiometry: 1.0
species: 283716
type: SpeciesReference

289229
product: 390699
notes: GENE_ASSOCIATION: YBR084W PROTEIN_ASSOCIATION: Mis1-m SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 6.3.4.3
reactant: 390638
type: Reaction
reactant: 390650
reactant: 390662
product: 390687
fast: false
reversible: false
kinetic law: 390711
product: 390674
name: R_formate_tetrahydrofolate_ligase__mitochondrial_irreversible

285679
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

285526
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

291046
value: 0.0
type: LocalParameter

303269
value: 999999.0
type: LocalParameter

287836
reversible: false
product: 360271
name: R_biotin_acetyl_CoA_carboxylase_ligase
type: Reaction
fast: false
notes: GENE_ASSOCIATION: YDL141W PROTEIN_ASSOCIATION: Bpl1 SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 6.3.4.15
reactant: 360259
reactant: 360234
reactant: 360246
product: 360283
kinetic law: 360295

407383
stoichiometry: 1.0
species: 284720
type: SpeciesReference

291191
value: 0.0
type: LocalParameter

376092
stoichiometry: 1.0
species: 284355
type: SpeciesReference

298099
value: 999999.0
type: LocalParameter

299462
value: 0.0
type: LocalParameter

292836
value: 0.0
type: LocalParameter

292145
value: 0.0
type: LocalParameter

291047
value: 999999.0
type: LocalParameter

299318
value: 0.0
type: LocalParameter

301660
value: 0.0
type: LocalParameter

290790
notes: GENE_ASSOCIATION: YBR021W PROTEIN_ASSOCIATION: Fur4 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
type: Reaction
reactant: 441082
product: 441107
reversible: false
fast: false
name: R_uracil_transport_in_via_proton_symport
reactant: 441095
product: 441119
kinetic law: 441131

302011
value: 2.85E-4
type: LocalParameter

293655
value: 0.0
type: LocalParameter

391605
stoichiometry: 1.0
species: 284787
type: SpeciesReference

303268
value: 0.0
type: LocalParameter

384060
stoichiometry: 8.0
species: 283530
type: SpeciesReference

348831
stoichiometry: 1.0
species: 284951
type: SpeciesReference

298098
value: 0.0
type: LocalParameter

363664
stoichiometry: 1.0
species: 284787
type: SpeciesReference

412198
stoichiometry: 0.01
species: 285898
type: SpeciesReference

299463
value: 0.0
type: LocalParameter

366550
stoichiometry: 1.0
species: 285454
type: SpeciesReference

346476
stoichiometry: 1.0
species: 283305
type: SpeciesReference

400988
stoichiometry: 1.0
species: 284909
type: SpeciesReference

421137
stoichiometry: 1.0
species: 284787
type: SpeciesReference

374802
stoichiometry: 1.0
species: 286606
type: SpeciesReference

292144
value: 0.0
type: LocalParameter

375730
stoichiometry: 1.0
species: 284100
type: SpeciesReference

439785
stoichiometry: 1.0
species: 283107
type: SpeciesReference

303267
value: 0.0
type: LocalParameter

284840
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Hexadecenoate__n_C161__C16H29O2
type: Species

299319
value: 0.0
type: LocalParameter

291193
value: 0.0
type: LocalParameter

351005
stoichiometry: 1.0
species: 283836
type: SpeciesReference

288968
kinetic law: 380233
product: 380221
reactant: 380208
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport
type: Reaction

287725
reversible: false
product: 357642
kinetic law: 357666
reactant: 357618
fast: false
name: R_L_asparaginase
product: 357654
reactant: 357630
type: Reaction
notes: GENE_ASSOCIATION: YDR321W PROTEIN_ASSOCIATION: Asp1 SUBSYSTEM: S_Asparagine_metabolism PROTEIN_CLASS: 3.5.1.1

294484
value: 0.0
type: LocalParameter

293358
value: 999999.0
type: LocalParameter

298097
value: 0.0
type: LocalParameter

295186
value: 0.0
type: LocalParameter

288545
kinetic law: 375103
product: 375091
reactant: 375079
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Allantoin_exchange
type: Reaction

288698
kinetic law: 376959
product: 376946
reactant: 376933
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Guanosine_exchange
type: Reaction

387815
stoichiometry: 6.0
species: 285436
type: SpeciesReference

293653
value: 999999.0
type: LocalParameter

393996
stoichiometry: 1.0
species: 284757
type: SpeciesReference

289018
kinetic law: 381211
product: 381199
reactant: 381187
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport
type: Reaction

290792
reactant: 441143
reactant: 441155
fast: false
product: 441167
kinetic law: 441192
reversible: true
notes: GENE_ASSOCIATION: YHL016C PROTEIN_ASSOCIATION: Dur3 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
name: R_urea_reversible_transport_via_proton_symport__2_H_
product: 441179
type: Reaction

295185
value: 0.0
type: LocalParameter

299465
value: -0.069492
type: LocalParameter

292834
value: 0.0
type: LocalParameter

372037
stoichiometry: 1.0
species: 285113
type: SpeciesReference

298389
value: 0.0
type: LocalParameter

291194
value: -999999.0
type: LocalParameter

282974
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_2_Amino_3_oxobutanoate_C4H7NO3
type: Species

289990
notes: GENE_ASSOCIATION: YKL067W PROTEIN_ASSOCIATION: Ynk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6
fast: false
product: 415455
reactant: 415442
product: 415467
kinetic law: 415479
reactant: 415430
reversible: true
name: R_nucleoside_diphosphate_kinase__ATPGDP_
type: Reaction

299546
value: 0.0
type: LocalParameter

284843
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Hexadecenoate__n_C161__C16H29O2
type: Species

299699
value: 0.085323
type: LocalParameter

293673
value: 999999.0
type: LocalParameter

386719
stoichiometry: 1.0
species: 284757
type: SpeciesReference

293516
value: 0.0
type: LocalParameter

443428
stoichiometry: 0.0663
species: 284897
type: SpeciesReference

300501
value: -0.139973
type: LocalParameter

397089
stoichiometry: 1.0
species: 284657
type: SpeciesReference

297863
value: 999999.0
type: LocalParameter

298590
value: 0.0
type: LocalParameter

388224
stoichiometry: 3.0
species: 284757
type: SpeciesReference

373075
stoichiometry: 1.0
species: 284757
type: SpeciesReference

301457
value: 999999.0
type: LocalParameter

288755
kinetic law: 377653
product: 377641
reactant: 377629
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Inosine_exchange
type: Reaction

283917
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ceramide_2__Phytosphingosinen_C240__C42H85NO4
type: Species

299484
value: 0.0
type: LocalParameter

289243
product: 391147
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS: 2.4.1.132
reactant: 391110
product: 391134
type: Reaction
reversible: false
name: R_Glycolipid_1_3_alpha_D_mannosyltransferase__Golgi_apparatus
kinetic law: 391159
fast: false
product: 391122
reactant: 391098

406005
stoichiometry: 1.0
species: 282947
type: SpeciesReference

292843
value: 0.0
type: LocalParameter

349966
stoichiometry: 2.0
species: 284796
type: SpeciesReference

359916
stoichiometry: 1.0
species: 285760
type: SpeciesReference

405472
stoichiometry: 1.0
species: 283122
type: SpeciesReference

299698
value: 0.0
type: LocalParameter

290678
reactant: 437500
product: 437549
type: Reaction
reactant: 437537
reversible: false
reactant: 437512
product: 437609
product: 437621
product: 437585
fast: false
product: 437597
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS:
reactant: 437524
product: 437573
name: R_thiazole_phosphate_synthesis__ribose_5_phosphate___yeast_specifc
reactant: 437488
product: 437561
kinetic law: 437633

363990
stoichiometry: 1.0
species: 283959
type: SpeciesReference

430127
stoichiometry: 1.0
species: 284787
type: SpeciesReference

300500
value: 0.0
type: LocalParameter

351997
stoichiometry: 0.05
species: 286099
type: SpeciesReference

294493
value: 0.0019
type: LocalParameter

298591
value: -0.036231
type: LocalParameter

357137
stoichiometry: 1.0
species: 286273
type: SpeciesReference

352117
stoichiometry: 1.0
species: 285760
type: SpeciesReference

297975
value: 999999.0
type: LocalParameter

437464
stoichiometry: 1.0
species: 285943
type: SpeciesReference

297862
value: 0.0
type: LocalParameter

388993
stoichiometry: 0.03
species: 286099
type: SpeciesReference

301458
value: 0.0
type: LocalParameter

435224
stoichiometry: 1.0
species: 285760
type: SpeciesReference

299483
value: 0.0
type: LocalParameter

292280
value: -999999.0
type: LocalParameter

299544
value: 999999.0
type: LocalParameter

404096
stoichiometry: 1.0
species: 284757
type: SpeciesReference

293675
value: 0.0
type: LocalParameter

292282
value: 999999.0
type: LocalParameter

374499
stoichiometry: 1.0
species: 283128
type: SpeciesReference

300713
value: 0.0
type: LocalParameter

405314
stoichiometry: 0.01
species: 285077
type: SpeciesReference

300927
value: 999999.0
type: LocalParameter

293518
value: 0.0
type: LocalParameter

298592
value: -999999.0
type: LocalParameter

440564
stoichiometry: 1.0
species: 286474
type: SpeciesReference

379266
stoichiometry: 1.0
species: 286078
type: SpeciesReference

297978
value: 0.0
type: LocalParameter

376796
stoichiometry: 1.0
species: 286771
type: SpeciesReference

289241
product: 391074
name: R_Glycolipid_1_2_alpha_D_mannosyltransferase__Golgi_apparatus
reactant: 391038
fast: false
notes: GENE_ASSOCIATION: ( YDR483W or YOR099W or YKR061W or YBR205W or YBR199W or YNL029C or YPL053C or YJL139C ) PROTEIN_ASSOCIATION: ( Kre2-g ) or ( Ktr1-g ) or ( Ktr2-g ) or ( Ktr3-g ) or ( Ktr4-g ) or ( Ktr5-g ) or ( Ktr6-g ) or ( Yur1-g ) SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS: 2.4.1.131
kinetic law: 391086
type: Reaction
reactant: 391026
reversible: false
product: 391050
product: 391062

369751
stoichiometry: 1.0
species: 286105
type: SpeciesReference

380945
stoichiometry: 1.0
species: 285637
type: SpeciesReference

303281
value: 0.0
type: LocalParameter

299543
value: 0.0
type: LocalParameter

283479
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Acetoacetyl_CoA_C25H36N7O18P3S
type: Species

292845
value: 0.04626
type: LocalParameter

284846
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

300712
value: 0.0
type: LocalParameter

290676
reactant: 437330
product: 437451
product: 437415
reactant: 437366
reactant: 437354
fast: false
reactant: 437342
type: Reaction
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS:
product: 437391
product: 437439
reversible: false
kinetic law: 437476
product: 437464
name: R_thiazole_phosphate_synthesis__xylulose_5_phosphate___yeast_specific
product: 437403
product: 437427
reactant: 437378

294490
value: 0.0
type: LocalParameter

433250
stoichiometry: 1.0
species: 286042
type: SpeciesReference

360077
stoichiometry: 1.0
species: 284787
type: SpeciesReference

442159
stoichiometry: 1.0
species: 284787
type: SpeciesReference

300926
value: 0.0
type: LocalParameter

298593
value: 999999.0
type: LocalParameter

368119
stoichiometry: 1.0
species: 284142
type: SpeciesReference

297864
value: 0.0
type: LocalParameter

288106
reactant: 366201
reactant: 366176
product: 366237
product: 366225
reversible: false
type: Reaction
kinetic law: 366249
fast: false
product: 366213
name: R_CTPCMP_antiport
reactant: 366189
notes: GENE_ASSOCIATION: YBR192W PROTEIN_ASSOCIATION: Rim2-m SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:

297977
value: 0.0
type: LocalParameter

371699
stoichiometry: 1.0
species: 285751
type: SpeciesReference

299481
value: 999999.0
type: LocalParameter

356631
stoichiometry: 1.0
species: 283422
type: SpeciesReference

299695
value: 999999.0
type: LocalParameter

300925
value: -0.17759
type: LocalParameter

288100
reactant: 365962
reversible: false
product: 366010
fast: false
kinetic law: 366034
product: 365986
type: Reaction
notes: GENE_ASSOCIATION: ( YBL039C or YJR103W ) PROTEIN_ASSOCIATION: ( Ura7 ) or ( Ura8 ) SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.2
reactant: 365974
product: 365998
name: R_CTP_synthase__NH3_
reactant: 365949
product: 366022

302158
value: -0.004158
type: LocalParameter

399973
stoichiometry: 1.0
species: 284823
type: SpeciesReference

290562
kinetic law: 433710
product: 433698
product: 433674
reversible: false
name: R_sphingolipid_long_chain_base_kinase__phytosphingosine_
reactant: 433649
product: 433686
notes: GENE_ASSOCIATION: ( YOR171C or YLR260W ) PROTEIN_ASSOCIATION: ( Lcb4 ) or ( Lcb5 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
type: Reaction
fast: false
reactant: 433662

292284
value: 0.0
type: LocalParameter

436603
stoichiometry: 1.0
species: 284760
type: SpeciesReference

284556
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Glycolaldehyde_C2H4O2
type: Species

303282
value: 0.0
type: LocalParameter

345849
stoichiometry: 1.0
species: 283992
type: SpeciesReference

420303
stoichiometry: 1.0
species: 283602
type: SpeciesReference

301452
value: 0.0
type: LocalParameter

299480
value: 0.0
type: LocalParameter

299694
value: 0.0
type: LocalParameter

421971
stoichiometry: 1.0
species: 284523
type: SpeciesReference

355520
stoichiometry: 1.0
species: 284757
type: SpeciesReference

381079
stoichiometry: 1.0
species: 284828
type: SpeciesReference

353200
stoichiometry: 1.0
species: 283647
type: SpeciesReference

298380
value: 0.0
type: LocalParameter

439616
stoichiometry: 1.0
species: 283458
type: SpeciesReference

285508
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Oxaloacetate_C4H2O5
type: Species

298596
value: 0.0
type: LocalParameter

374983
stoichiometry: 1.0
species: 286621
type: SpeciesReference

434765
stoichiometry: 2.0
species: 284787
type: SpeciesReference

290674
product: 437294
product: 437306
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
kinetic law: 437318
reversible: true
type: Reaction
reactant: 437269
reactant: 437282
name: R_thymine_reversible_transport_via_proton_antiport

292128
value: 999999.0
type: LocalParameter

299549
value: 0.0
type: LocalParameter

378844
stoichiometry: 1.0
species: 286939
type: SpeciesReference

289247
kinetic law: 391267
product: 391255
reactant: 391243
notes: GENE_ASSOCIATION: YCR098C PROTEIN_ASSOCIATION: Git1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_glycero_3_phosphocholine_transport__extracellular_to_cytosol_
type: Reaction

303283
value: 999999.0
type: LocalParameter

301453
value: 0.0
type: LocalParameter

299693
value: -0.01663
type: LocalParameter

346682
stoichiometry: 1.0
species: 284757
type: SpeciesReference

366780
stoichiometry: 1.0
species: 285796
type: SpeciesReference

362748
stoichiometry: 1.0
species: 286072
type: SpeciesReference

289994
product: 415587
reactant: 415563
type: Reaction
fast: false
name: R_nucleoside_diphosphate_kinase__ATPCDP_
kinetic law: 415599
product: 415575
notes: GENE_ASSOCIATION: YKL067W PROTEIN_ASSOCIATION: Ynk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6
reactant: 415551
reversible: true

297979
value: -0.004158
type: LocalParameter

298595
value: 0.0
type: LocalParameter

298381
value: 0.0
type: LocalParameter

293519
value: -999999.0
type: LocalParameter

290899
value: -0.076083
type: LocalParameter

443656
stoichiometry: 1.0E-6
species: 286171
type: SpeciesReference

419167
stoichiometry: 1.0
species: 285922
type: SpeciesReference

284849
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

292286
value: 0.0
type: LocalParameter

301454
value: -999999.0
type: LocalParameter

379048
stoichiometry: 1.0
species: 285988
type: SpeciesReference

430723
stoichiometry: 1.0
species: 285973
type: SpeciesReference

290560
product: 433600
reactant: 433576
reactant: 433588
reversible: false
kinetic law: 433637
product: 433625
type: Reaction
notes: GENE_ASSOCIATION: ( YLR260W or YOR171C ) PROTEIN_ASSOCIATION: ( Lcb5 ) or ( Lcb4 ) SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 433612
fast: false
name: R_sphingolipid_long_chain_base_kinase__sphinganine_

289992
type: Reaction
notes: GENE_ASSOCIATION: YKL067W PROTEIN_ASSOCIATION: Ynk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6
name: R_nucleoside_diphosphate_kinase__ATPUDP_
fast: false
reactant: 415491
reactant: 415503
product: 415515
kinetic law: 415539
product: 415527
reversible: true

289245
product: 391207
product: 391195
name: R_Glycolipid_1_6_alpha_D_mannosyltransferase__Golgi_apparatus
reversible: false
type: Reaction
reactant: 391183
product: 391219
fast: false
reactant: 391171
kinetic law: 391231
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS:

288950
kinetic law: 380015
product: 380002
reactant: 379990
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Xanthine_exchange
type: Reaction

441095
stoichiometry: 1.0
species: 286471
type: SpeciesReference

299692
value: 0.0
type: LocalParameter

425424
stoichiometry: 1.0
species: 283992
type: SpeciesReference

352838
stoichiometry: 1.0
species: 284787
type: SpeciesReference

288103
reversible: false
notes: GENE_ASSOCIATION: ( YBL039C or YJR103W ) PROTEIN_ASSOCIATION: ( Ura7 ) or ( Ura8 ) SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.2
kinetic law: 366163
type: Reaction
name: R_CTP_synthase__glutamine_
product: 366137
fast: false
reactant: 366072
product: 366124
product: 366098
reactant: 366047
product: 366150
reactant: 366085
reactant: 366059
product: 366111

297861
value: 0.0
type: LocalParameter

356486
stoichiometry: 1.0
species: 283728
type: SpeciesReference

284559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Glycolaldehyde_C2H4O2
type: Species

298598
value: 0.0
type: LocalParameter

302159
value: 0.0
type: LocalParameter

303285
value: 0.0
type: LocalParameter

300922
value: 0.0
type: LocalParameter

292841
value: 999999.0
type: LocalParameter

290672
notes: GENE_ASSOCIATION: ( YKR039W or YBR069C or YCL025C or YDR508C ) PROTEIN_ASSOCIATION: ( Gap1 ) or ( Tat1 ) or ( Agp1 ) or ( Gnp1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reactant: 437221
kinetic law: 437257
reactant: 437209
name: R_L_threonine_reversible_transport_via_proton_symport
type: Reaction
reversible: true
fast: false
product: 437233
product: 437245

293670
value: 0.0
type: LocalParameter

299547
value: 0.0
type: LocalParameter

288752
kinetic law: 377617
product: 377605
reactant: 377592
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_myo_Inositol_exchange
type: Reaction

298383
value: 0.0
type: LocalParameter

353357
stoichiometry: 1.0
species: 284790
type: SpeciesReference

366670
stoichiometry: 1.0
species: 284827
type: SpeciesReference

293948
value: 0.0
type: LocalParameter

414884
stoichiometry: 1.0
species: 285853
type: SpeciesReference

298170
value: 999999.0
type: LocalParameter

289357
kinetic law: 394781
reactant: 394733
name: R_glutamine_nuclear_transport_via_proton_symport
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
type: Reaction
product: 394757
reversible: true
fast: false
reactant: 394745
product: 394769

292288
value: 0.0
type: LocalParameter

300921
value: 0.0
type: LocalParameter

289570
reactant: 401529
product: 401553
fast: false
reactant: 401505
reversible: true
product: 401565
product: 401541
name: R_Hydroxymethylglutaryl_CoA_reductase
type: Reaction
kinetic law: 401577
notes: GENE_ASSOCIATION: ( YLR450W or YML075C ) PROTEIN_ASSOCIATION: ( Hmg2 ) or ( Hmg1 ) SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 1.1.1.34
reactant: 401517

289784
product: 408662
type: Reaction
reactant: 408614
fast: false
reactant: 408602
name: R_malate_synthase
product: 408650
product: 408638
kinetic law: 408674
notes: GENE_ASSOCIATION: ( YIR031C or YNL117W ) PROTEIN_ASSOCIATION: ( Dal7 ) or ( Mls1 ) SUBSYSTEM: S_Anaplerotic_Reactions PROTEIN_CLASS: 4.1.3.2
reversible: false
reactant: 408626

290566
kinetic law: 433820
product: 433807
reactant: 433795
notes: GENE_ASSOCIATION: YPL092W PROTEIN_ASSOCIATION: Ssu1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_sulfite_transport__efflux__cytosol_to_extracellular_
type: Reaction

302009
value: 0.0
type: LocalParameter

352514
stoichiometry: 1.0
species: 282889
type: SpeciesReference

427173
stoichiometry: 1.0
species: 284796
type: SpeciesReference

346573
stoichiometry: 1.0
species: 284766
type: SpeciesReference

289998
type: Reaction
name: R_nucleoside_diphosphate_kinase__ATPdGDP_
reactant: 415671
reactant: 415683
fast: false
reversible: true
kinetic law: 415719
product: 415707
notes: GENE_ASSOCIATION: YKL067W PROTEIN_ASSOCIATION: Ynk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6
product: 415695

438806
stoichiometry: 1.0
species: 284787
type: SpeciesReference

427028
stoichiometry: 1.0
species: 285856
type: SpeciesReference

426292
stoichiometry: 1.0
species: 282981
type: SpeciesReference

289355
name: R_Glutaminyl_tRNA_synthetase
reversible: false
reactant: 394660
type: Reaction
product: 394697
reactant: 394648
product: 394684
reactant: 394672
product: 394709
kinetic law: 394721
fast: false
notes: GENE_ASSOCIATION: YOR168W PROTEIN_ASSOCIATION: Gln4 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.18

290670
reactant: 437161
product: 437173
reactant: 437149
product: 437185
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
type: Reaction
reversible: true
fast: false
name: R_threonine_mitochondrial_transport_via_proton_symport
kinetic law: 437197

284553
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Glycolaldehyde_C2H4O2
type: Species

284400
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_2_6_bisphosphate_C6H10O12P2
type: Species

301344
value: 0.04626
type: LocalParameter

292289
value: -999999.0
type: LocalParameter

283473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Aminoacetaldehyde_C2H6NO
type: Species

302153
value: 999999.0
type: LocalParameter

369874
stoichiometry: 1.0
species: 284787
type: SpeciesReference

297970
value: 0.0
type: LocalParameter

370720
stoichiometry: 1.0
species: 284574
type: SpeciesReference

344750
stoichiometry: 1.0
species: 283056
type: SpeciesReference

362856
stoichiometry: 1.0
species: 284013
type: SpeciesReference

298172
value: 0.0
type: LocalParameter

435116
stoichiometry: 1.0
species: 286105
type: SpeciesReference

301346
value: -999999.0
type: LocalParameter

425316
stoichiometry: 2.0
species: 285760
type: SpeciesReference

301345
value: 0.0
type: LocalParameter

400772
stoichiometry: 1.0
species: 285487
type: SpeciesReference

385449
stoichiometry: 2.0
species: 285436
type: SpeciesReference

363108
stoichiometry: 1.0
species: 284876
type: SpeciesReference

290564
name: R_sulfate_adenylyltransferase__ADP_
reversible: true
product: 433771
fast: false
notes: GENE_ASSOCIATION: YCL050C PROTEIN_ASSOCIATION: Apa1 SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 2.7.7.5
kinetic law: 433783
product: 433759
type: Reaction
reactant: 433723
reactant: 433747
reactant: 433735

289782
reversible: true
reactant: 408554
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
type: Reaction
product: 408566
reactant: 408542
product: 408578
name: R_malateoxaloacetate_shuttle
kinetic law: 408590

302156
value: 0.0
type: LocalParameter

419276
stoichiometry: 1.0
species: 283551
type: SpeciesReference

297211
value: 0.0
type: LocalParameter

288259
kinetic law: 369641
product: 369629
reactant: 369617
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_dhnpt_mitochondrial_transport
type: Reaction

283470
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_trans_4_Hydroxycinnamate_C9H7O3
type: Species

427778
stoichiometry: 1.0
species: 285859
type: SpeciesReference

357462
stoichiometry: 1.0
species: 283695
type: SpeciesReference

434693
stoichiometry: 1.0
species: 286096
type: SpeciesReference

289353
reactant: 394551
notes: GENE_ASSOCIATION: YPR035W PROTEIN_ASSOCIATION: Gln1 SUBSYSTEM: S_Glutamine_Metabolism PROTEIN_CLASS: 6.3.1.2
product: 394624
reactant: 394575
type: Reaction
product: 394587
reactant: 394563
kinetic law: 394636
fast: false
product: 394599
product: 394612
reversible: false
name: R_glutamine_synthetase

289996
reactant: 415611
fast: false
type: Reaction
name: R_nucleoside_diphosphate_kinase__ATPdTDP_
product: 415647
kinetic law: 415659
product: 415635
notes: GENE_ASSOCIATION: YKL067W PROTEIN_ASSOCIATION: Ynk1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6
reversible: true
reactant: 415623

298173
value: 0.0
type: LocalParameter

287382
kinetic law: 350074
product: 350062
reactant: 350050
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_acetylcarnitine_transport_out_of_peroxisome
type: Reaction

285080
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

302155
value: 0.0
type: LocalParameter

287158
type: Reaction
reactant: 345811
kinetic law: 345861
reactant: 345824
fast: false
notes: GENE_ASSOCIATION: ( YLR134W or YLR044C or ( YGR087C and YGR087C ) ) PROTEIN_ASSOCIATION: ( Pdc5 ) or ( Pdc1 ) or ( Pdc6 ) or ( Pdc6 ) SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS:
name: R_3_Methyl_2_oxobutanoate_decarboxylase
reversible: false
product: 345836
product: 345849

297867
value: -0.011879
type: LocalParameter

426098
stoichiometry: 1.0
species: 283830
type: SpeciesReference

288109
product: 366309
notes: GENE_ASSOCIATION: ( ( ( Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YLR038C and YLR395C and YMR256C and YNL052W ) and YEL039C ) or ( ( Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YLR038C and YLR395C and YMR256C and YNL052W ) and YJR048W ) or ( ( Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YIL111W and YLR038C and YLR395C and YMR256C ) and YJR048W ) or ( ( Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YIL111W and YLR038C and YLR395C and YMR256C ) and YEL039C ) ) PROTEIN_ASSOCIATION: ( Cco1-m and Cyc7-m ) or ( Cco1-m and Cyc1-m ) or ( Cco2-m and Cyc1-m ) or ( Cco2-m and Cyc7-m ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.9.3.1
reversible: false
type: Reaction
reactant: 366261
name: R_cytochrome_c_oxidase__mitochondrial
product: 366297
kinetic law: 366333
product: 366321
reactant: 366273
fast: false
reactant: 366285

357245
stoichiometry: 1.0
species: 283779
type: SpeciesReference

297972
value: 0.0
type: LocalParameter

297213
value: 999999.0
type: LocalParameter

388332
stoichiometry: 4.0
species: 284013
type: SpeciesReference

289574
reversible: true
product: 401721
product: 401733
reactant: 401697
reactant: 401673
fast: false
kinetic law: 401745
type: Reaction
product: 401709
reactant: 401685
name: R_Hydroxymethylglutaryl_CoA_synthase__mitochondrial
notes: GENE_ASSOCIATION: YML126C PROTEIN_ASSOCIATION: Erg13-m SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 4.1.3.5

284403
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Fructose_6_phosphate_C6H11O9P
type: Species

293512
value: 999999.0
type: LocalParameter

390480
stoichiometry: 1.0
species: 284757
type: SpeciesReference

285083
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Isopentenyl_diphosphate_C5H9O7P2
type: Species

372473
stoichiometry: 1.0
species: 283161
type: SpeciesReference

299542
value: 0.0
type: LocalParameter

298175
value: 0.0
type: LocalParameter

432475
stoichiometry: 1.0
species: 284787
type: SpeciesReference

301349
value: 999999.0
type: LocalParameter

299540
value: 0.0
type: LocalParameter

289351
kinetic law: 394539
product: 394527
reactant: 394515
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
fast: false
reversible: true
name: R_glucose_transport__vacuolar
type: Reaction

422237
stoichiometry: 1.0
species: 283641
type: SpeciesReference

414230
stoichiometry: 1.0
species: 285421
type: SpeciesReference

297866
value: 0.0
type: LocalParameter

289788
kinetic law: 408807
product: 408795
reactant: 408783
reactant: 408771
notes: GENE_ASSOCIATION: ( YBR299W or YGR292W or YJL221C or YGR287C or YIL172C or YJL216C ) PROTEIN_ASSOCIATION: ( Mal32 ) or ( Mal12 ) or ( Fsp2 ) or ( Mal33 ) or ( Mal13 ) or ( Mal14 ) SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 3.2.1.20
fast: false
reversible: false
name: R_alpha_glucosidase
type: Reaction

437573
stoichiometry: 1.0
species: 283497
type: SpeciesReference

397778
stoichiometry: 1.0
species: 284714
type: SpeciesReference

372787
stoichiometry: 1.0
species: 283653
type: SpeciesReference

443536
stoichiometry: 4.5E-5
species: 285679
type: SpeciesReference

288482
kinetic law: 374342
product: 374330
reactant: 374318
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_methylbutyl_acetate_exchange
type: Reaction

357859
stoichiometry: 1.0
species: 283782
type: SpeciesReference

368047
stoichiometry: 1.0
species: 284139
type: SpeciesReference

350183
stoichiometry: 1.0
species: 283836
type: SpeciesReference

386827
stoichiometry: 1.0
species: 283992
type: SpeciesReference

300718
value: 999999.0
type: LocalParameter

356787
stoichiometry: 1.0
species: 285436
type: SpeciesReference

359807
stoichiometry: 3.0
species: 284787
type: SpeciesReference

297869
value: 999999.0
type: LocalParameter

383831
stoichiometry: 6.0
species: 285418
type: SpeciesReference

298176
value: 0.0
type: LocalParameter

436797
stoichiometry: 1.0
species: 284657
type: SpeciesReference

393223
stoichiometry: 1.0
species: 283689
type: SpeciesReference

297974
value: 0.0
type: LocalParameter

396242
stoichiometry: 1.0
species: 284654
type: SpeciesReference

288485
kinetic law: 374378
product: 374366
reactant: 374354
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_methylbutyraldehyde_exchange
type: Reaction

283476
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetoacetyl_CoA_C25H36N7O18P3S
type: Species

293514
value: 0.0
type: LocalParameter

297215
value: 0.0
type: LocalParameter

302152
value: 0.0
type: LocalParameter

289572
reactant: 401601
product: 401649
name: R_Hydroxymethylglutaryl_CoA_synthase
product: 401625
reactant: 401613
fast: false
kinetic law: 401661
type: Reaction
product: 401637
reversible: true
notes: GENE_ASSOCIATION: YML126C PROTEIN_ASSOCIATION: Erg13 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 4.1.3.5
reactant: 401589

345702
stoichiometry: 1.0
species: 283182
type: SpeciesReference

290568
kinetic law: 433858
product: 433846
reactant: 433833
notes: GENE_ASSOCIATION: ( YBR294W or YLR092W or YGR125W ) PROTEIN_ASSOCIATION: ( Sul1 ) or ( Sul2 ) or ( Sul3 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_sulfate_irreversible_uniport
type: Reaction

390119
stoichiometry: 1.0
species: 284481
type: SpeciesReference

400688
stoichiometry: 1.0
species: 284876
type: SpeciesReference

401613
stoichiometry: 1.0
species: 284924
type: SpeciesReference

287155
kinetic law: 345799
product: 345787
reactant: 345775
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_methylbutanal_transport__mitochondrial_
type: Reaction

284550
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_N1__5_Phospho_D_ribosyl_glycinamide_C7H14N2O8P
type: Species

300717
value: 0.0
type: LocalParameter

289129
reversible: false
product: 386491
reactant: 386443
type: Reaction
kinetic law: 386515
name: R_fatty_acid_synthase__n_C160_
reactant: 386419
product: 386503
fast: false
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reactant: 386407
product: 386455
reactant: 386431
product: 386479
product: 386467

409580
stoichiometry: 1.0
species: 285213
type: SpeciesReference

283809
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_L_Aspartate_C4H6NO4
type: Species

376686
stoichiometry: 1.0
species: 286762
type: SpeciesReference

297868
value: 0.0
type: LocalParameter

437427
stoichiometry: 1.0
species: 283992
type: SpeciesReference

375440
stoichiometry: 1.0
species: 283953
type: SpeciesReference

384504
stoichiometry: 2.0
species: 285433
type: SpeciesReference

348699
stoichiometry: 1.0
species: 283551
type: SpeciesReference

298177
value: 999999.0
type: LocalParameter

413783
stoichiometry: 1.0
species: 285421
type: SpeciesReference

379374
stoichiometry: 1.0
species: 286108
type: SpeciesReference

289786
reversible: false
fast: false
name: R_malate_synthase
reactant: 408710
type: Reaction
notes: GENE_ASSOCIATION: ( YIR031C or YNL117W ) PROTEIN_ASSOCIATION: ( Dal7-p ) or ( Mls1-p ) SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.3.2
product: 408747
reactant: 408686
product: 408735
product: 408723
reactant: 408698
kinetic law: 408759

397197
stoichiometry: 1.0
species: 284690
type: SpeciesReference

394046
stoichiometry: 1.0
species: 286174
type: SpeciesReference

371542
stoichiometry: 1.0
species: 284292
type: SpeciesReference

297973
value: 0.0
type: LocalParameter

284406
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

417334
stoichiometry: 1.0
species: 284139
type: SpeciesReference

435924
stoichiometry: 1.0
species: 284805
type: SpeciesReference

297214
value: 0.0
type: LocalParameter

344336
stoichiometry: 1.0
species: 283008
type: SpeciesReference

433141
stoichiometry: 1.0
species: 284277
type: SpeciesReference

442268
stoichiometry: 1.0
species: 286516
type: SpeciesReference

298178
value: 0.0
type: LocalParameter

419372
stoichiometry: 1.0
species: 284787
type: SpeciesReference

301560
value: 0.0
type: LocalParameter

302151
value: -0.377156
type: LocalParameter

300716
value: -0.268661
type: LocalParameter

367189
stoichiometry: 1.0
species: 283602
type: SpeciesReference

285074
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

405074
stoichiometry: 0.01
species: 285065
type: SpeciesReference

298168
value: 0.0
type: LocalParameter

283803
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Aspartate_C4H6NO4
type: Species

301562
value: 0.0
type: LocalParameter

352946
stoichiometry: 1.0
species: 283641
type: SpeciesReference

351101
stoichiometry: 1.0
species: 283716
type: SpeciesReference

289566
kinetic law: 401433
reactant: 401397
reactant: 401385
product: 401409
reversible: false
type: Reaction
product: 401421
notes: GENE_ASSOCIATION: YLR231C PROTEIN_ASSOCIATION: Bna5 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 3.7.1.3
name: R_3_Hydroxy_L_kynurenine_hydrolase
fast: false

287716
name: R_L_arginine_transport_in_via_proton_antiport__vacuolar_
product: 357438
reactant: 357414
type: Reaction
reactant: 357402
kinetic law: 357450
reversible: false
product: 357426
fast: false
notes: GENE_ASSOCIATION: YBR293W PROTEIN_ASSOCIATION: Vba2-v SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:

288689
kinetic law: 376845
product: 376832
reactant: 376820
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Glyoxylate_exchange
type: Reaction

363543
stoichiometry: 1.0
species: 283920
type: SpeciesReference

412077
stoichiometry: 0.01
species: 285898
type: SpeciesReference

287821
product: 359855
notes: GENE_ASSOCIATION: ( YBR127C and YDL185W and YEL027W and YEL051W and YGR020C and YHR026W and YHR039C-A and YKL080W and YLR447C and YMR054W and YOR332W and YPL234C and YPR036W ) PROTEIN_ASSOCIATION: Hatp-g SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS:
product: 359843
type: Reaction
reactant: 359807
name: R_ATP_synthase__Golgi_Apparatus
reversible: false
kinetic law: 359880
fast: false
product: 359868
reactant: 359831
reactant: 359819

414665
stoichiometry: 1.0
species: 283713
type: SpeciesReference

287167
kinetic law: 345994
product: 345981
reactant: 345969
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_3mop_reversible_trasport
type: Reaction

366453
stoichiometry: 1.0
species: 283497
type: SpeciesReference

346355
stoichiometry: 1.0
species: 284028
type: SpeciesReference

289139
product: 387115
reactant: 387055
product: 387079
fast: false
name: R_fatty_acid_synthase__n_C180_
reactant: 387043
type: Reaction
kinetic law: 387139
reactant: 387067
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
product: 387103
reactant: 387031
product: 387127
product: 387091
reversible: false

298167
value: 0.047411
type: LocalParameter

393875
stoichiometry: 1.0
species: 284675
type: SpeciesReference

301561
value: 0.0
type: LocalParameter

283329
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Methyl_2_oxopentanoate_C6H9O3
type: Species

375947
stoichiometry: 1.0
species: 284292
type: SpeciesReference

297217
value: -0.102159
type: LocalParameter

375874
stoichiometry: 1.0
species: 284187
type: SpeciesReference

290784
kinetic law: 440950
product: 440938
product: 440926
reactant: 440914
notes: GENE_ASSOCIATION: YOR278W PROTEIN_ASSOCIATION: Hem4 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS: 4.2.1.75
fast: false
reversible: false
name: R_uroporphyrinogen_III_synthase
type: Reaction

302001
value: 999999.0
type: LocalParameter

288476
kinetic law: 374270
product: 374258
reactant: 374246
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_1_3_beta_D_Glucan_exchange
type: Reaction

380837
stoichiometry: 1.0
species: 286411
type: SpeciesReference

283326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Maleylacetoacetate_C8H6O6
type: Species

403708
stoichiometry: 1.0
species: 283830
type: SpeciesReference

287164
kinetic law: 345957
product: 345945
reversible: false
fast: false
reactant: 345921
product: 345933
name: R_3_Methyl_2_oxopentanoate_decarboxylase
reactant: 345909
notes: GENE_ASSOCIATION: ( YLR044C or YDL080C or YLR134W or YGR087C or YDR380W ) PROTEIN_ASSOCIATION: ( Pdc1 ) or ( Thi3 ) or ( Pdc5 ) or ( Pdc6 ) or ( Aro10 ) SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS:
type: Reaction

282965
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Amino_4_hydroxy_6_hydroxymethyl_7_8_dihydropteridine_diphosphate_C7H8N5O8P2
type: Species

443103
stoichiometry: 1.0
species: 286549
type: SpeciesReference

288262
fast: false
product: 369677
reactant: 369653
kinetic law: 369702
reversible: false
name: R_dihydoorotic_acid__ubiquinone_6___irreversible
type: Reaction
notes: GENE_ASSOCIATION: YKL216W PROTEIN_ASSOCIATION: Ura1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.3.3.1
product: 369689
reactant: 369665

302002
value: 0.0
type: LocalParameter

391725
stoichiometry: 1.0
species: 285436
type: SpeciesReference

363253
stoichiometry: 1.0
species: 283902
type: SpeciesReference

383286
stoichiometry: 1.0
species: 284025
type: SpeciesReference

436457
stoichiometry: 1.0
species: 286228
type: SpeciesReference

285077
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

289135
name: R_fatty_acid_synthase__n_C161_
notes: GENE_ASSOCIATION: YJL196C PROTEIN_ASSOCIATION: Elo1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reversible: false
fast: false
kinetic law: 386887
product: 386851
type: Reaction
product: 386827
reactant: 386767
product: 386863
product: 386839
product: 386875
reactant: 386791
reactant: 386779
reactant: 386803
reactant: 386815

362047
stoichiometry: 1.0
species: 283902
type: SpeciesReference

287379
kinetic law: 350038
product: 350026
reactant: 350014
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_O_acetylcarnintine_transport_into_mitochondria_via_diffusion
type: Reaction

302160
value: 999999.0
type: LocalParameter

297219
value: 0.0
type: LocalParameter

365865
stoichiometry: 1.0
species: 283530
type: SpeciesReference

293942
value: 0.0
type: LocalParameter

285511
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Oxaloacetate_C4H2O5
type: Species

289137
product: 386995
reactant: 386947
name: R_fatty_acyl_ACP_synthase__n_C161ACP___mitochondrial
fast: false
reactant: 386911
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
type: Reaction
product: 386959
product: 386983
reactant: 386899
product: 387007
kinetic law: 387019
reactant: 386935
reversible: false
product: 386971
reactant: 386923

298169
value: -999999.0
type: LocalParameter

290782
fast: false
reversible: false
product: 440878
type: Reaction
name: R_uroporphyrinogen_methyltransferase
reactant: 440854
reactant: 440842
product: 440866
kinetic law: 440902
product: 440890
notes: GENE_ASSOCIATION: YKR069W PROTEIN_ASSOCIATION: Met1 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS: 2.1.1.107

288530
kinetic law: 374922
product: 374910
reactant: 374898
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Acetic_ester_exchange
type: Reaction

414944
stoichiometry: 1.0
species: 285393
type: SpeciesReference

289564
reactant: 401325
notes: GENE_ASSOCIATION: ( YBR293W or YMR088C or YCL069W ) PROTEIN_ASSOCIATION: ( Vba2-v ) or ( Vba1-v ) or ( Vba3-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
type: Reaction
reactant: 401337
kinetic law: 401373
product: 401361
reversible: false
name: R_L_histidine_transport_in_via_proton_antiport__vacuolar_
product: 401349
fast: false

348820
stoichiometry: 1.0
species: 284757
type: SpeciesReference

293360
value: 0.0
type: LocalParameter

295176
value: 999999.0
type: LocalParameter

283806
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_L_Aspartate_C4H6NO4
type: Species

302004
value: -0.232567
type: LocalParameter

429353
stoichiometry: 1.0
species: 284787
type: SpeciesReference

291052
value: 0.082387
type: LocalParameter

443754
stoichiometry: 0.2646
species: 286495
type: SpeciesReference

364209
stoichiometry: 1.0
species: 283965
type: SpeciesReference

429208
stoichiometry: 1.0
species: 286510
type: SpeciesReference

299323
value: 0.0
type: LocalParameter

432319
stoichiometry: 1.0
species: 284772
type: SpeciesReference

293943
value: -999999.0
type: LocalParameter

375512
stoichiometry: 1.0
species: 283995
type: SpeciesReference

301340
value: 999999.0
type: LocalParameter

364354
stoichiometry: 1.0
species: 283962
type: SpeciesReference

289020
reactant: 381235
product: 381271
product: 381283
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
reversible: false
product: 381259
kinetic law: 381307
name: R_fatty_acyl_CoA_peroxisomal_transport_via_ABC_system
product: 381295
reactant: 381247
reactant: 381223
fast: false
type: Reaction

407225
stoichiometry: 1.0
species: 284787
type: SpeciesReference

425532
stoichiometry: 1.0
species: 285967
type: SpeciesReference

384492
stoichiometry: 8.0
species: 285418
type: SpeciesReference

289133
product: 386731
product: 386707
product: 386695
reactant: 386659
product: 386743
product: 386719
reversible: false
reactant: 386671
type: Reaction
fast: false
name: R_fatty_acyl_CoA_synthase__n_C160CoA_
reactant: 386647
reactant: 386683
kinetic law: 386755
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86

406692
stoichiometry: 0.27
species: 285541
type: SpeciesReference

396664
stoichiometry: 1.0
species: 284787
type: SpeciesReference

411304
stoichiometry: 1.0
species: 285300
type: SpeciesReference

413563
stoichiometry: 1.0
species: 285421
type: SpeciesReference

288479
kinetic law: 374306
product: 374294
reactant: 374282
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_Hydroxybutyrate_exchange
type: Reaction

290788
kinetic law: 441070
notes: GENE_ASSOCIATION: YHR128W PROTEIN_ASSOCIATION: Fur1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.9
type: Reaction
reactant: 441034
name: R_uracil_phosphoribosyltransferase
product: 441046
reactant: 441022
reversible: false
product: 441058
fast: false

368264
stoichiometry: 1.0
species: 284148
type: SpeciesReference

302005
value: 0.0
type: LocalParameter

288265
fast: false
notes: GENE_ASSOCIATION: YKL216W PROTEIN_ASSOCIATION: Ura1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS:
name: R_Fumarate_dependent_DHORD
reactant: 369714
reactant: 369726
type: Reaction
reversible: false
product: 369738
product: 369751
kinetic law: 369763

390335
stoichiometry: 1.0
species: 283602
type: SpeciesReference

289792
product: 408916
name: R_L_malate_reversible_transport_via_proton_symport
reactant: 408892
reactant: 408880
product: 408904
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
type: Reaction
reversible: true
fast: false
kinetic law: 408928

283800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Aspartate_C4H6NO4
type: Species

293944
value: 999999.0
type: LocalParameter

414339
stoichiometry: 1.0
species: 285396
type: SpeciesReference

373751
stoichiometry: 0.01
species: 284870
type: SpeciesReference

289349
kinetic law: 394503
product: 394491
reactant: 394479
notes: GENE_ASSOCIATION: ( YHR092C or YLR081W or YOL156W or YDR536W or YHR094C or YEL069C or YDL245C or YJR158W or YFL011W or YNR072W or YMR011W or YDR345C or YHR096C or YDR343C or YDR342C or YJL214W or YJL219W ) PROTEIN_ASSOCIATION: ( Hxt4 ) or ( Gal2 ) or ( Hxt11 ) or ( Stl1 ) or ( Hxt1 ) or ( Hxt13 ) or ( Hxt15 ) or ( Hxt16 ) or ( Hxt10 ) or ( Hxt17 ) or ( Hxt2 ) or ( Hxt3 ) or ( Hxt5 ) or ( Hxt6 ) or ( Hxt7 ) or ( Hxt8 ) or ( Hxt9 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_glucose_transport__uniport_
type: Reaction

358306
stoichiometry: 1.0
species: 284787
type: SpeciesReference

369423
stoichiometry: 1.0
species: 283830
type: SpeciesReference

287161
kinetic law: 345897
product: 345885
reactant: 345873
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_3_methyl_2_oxobutanoate_transport__diffusion__mitochondrial
type: Reaction

301565
value: 999999.0
type: LocalParameter

379591
stoichiometry: 1.0
species: 286207
type: SpeciesReference

301566
value: 0.0
type: LocalParameter

287376
product: 349978
name: R_acyl_carrier_protein_synthase__mitochondrial
kinetic law: 350002
reversible: false
product: 349990
notes: GENE_ASSOCIATION: YPL148C PROTEIN_ASSOCIATION: Ppt2-m SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS:
product: 349966
fast: false
reactant: 349942
reactant: 349954
type: Reaction

293362
value: 6.33E-4
type: LocalParameter

302006
value: 0.0
type: LocalParameter

291050
value: 0.0
type: LocalParameter

344118
stoichiometry: 1.0
species: 282987
type: SpeciesReference

293945
value: 0.0
type: LocalParameter

295179
value: 0.0
type: LocalParameter

301569
value: 0.0
type: LocalParameter

299320
value: 999999.0
type: LocalParameter

419590
stoichiometry: 1.0
species: 285610
type: SpeciesReference

293258
value: 999999.0
type: LocalParameter

289131
fast: false
product: 386587
reactant: 386527
kinetic law: 386635
product: 386575
reactant: 386563
product: 386623
reactant: 386551
name: R_fatty_acyl_ACP_synthase__n_C160ACP___mitochondrial
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
product: 386599
product: 386611
reactant: 386539

388116
stoichiometry: 6.0
species: 285427
type: SpeciesReference

289568
product: 401469
name: R_hydroxymethylbilane_synthase
reversible: false
reactant: 401445
type: Reaction
product: 401481
notes: GENE_ASSOCIATION: YDL205C PROTEIN_ASSOCIATION: Hem3 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS: 4.3.1.8
kinetic law: 401493
reactant: 401457
fast: false

415029
stoichiometry: 1.0
species: 284787
type: SpeciesReference

395302
stoichiometry: 1.0
species: 284787
type: SpeciesReference

288328
notes: GENE_ASSOCIATION: YNR043W PROTEIN_ASSOCIATION: Mvd1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 4.1.1.33
product: 371081
product: 371045
type: Reaction
reactant: 371021
product: 371057
kinetic law: 371094
reversible: false
fast: false
name: R_diphosphomevalonate_decarboxylase
product: 371069
reactant: 371033

396981
stoichiometry: 1.0
species: 285796
type: SpeciesReference

283323
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Methyl_5__2_hydroxyethyl__thiazole_C6H9NOS
type: Species

290786
product: 440986
type: Reaction
fast: false
reactant: 440962
product: 440998
notes: GENE_ASSOCIATION: YDR047W PROTEIN_ASSOCIATION: Hem12 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS: 4.1.1.37
reactant: 440974
reversible: false
kinetic law: 441010
name: R_uroporphyrinogen_decarboxylase__uroporphyrinogen_III_

289790
reactant: 408819
notes: GENE_ASSOCIATION: ( YGR289C or YBR298C or YDL247W or YJR160C ) PROTEIN_ASSOCIATION: ( Mal11 ) or ( Mal31 ) or ( Mph2 ) or ( Mph3 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 408855
fast: false
product: 408843
reactant: 408831
kinetic law: 408868
type: Reaction
reversible: false
name: R_maltose_transport_in_via_proton_symport

282968
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Amino_4_hydroxy_6_hydroxymethyl_7_8_dihydropteridine_C7H9N5O2
type: Species

301341
value: 0.0
type: LocalParameter

287373
name: R_acid_phosphatase__extracellular__secreted_
product: 349906
notes: GENE_ASSOCIATION: ( YBR093C or YAR071W ) PROTEIN_ASSOCIATION: ( Pho5-e ) or ( Pho11-e ) SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS: 3.1.3.2
type: Reaction
kinetic law: 349930
reactant: 349882
reversible: false
product: 349918
reactant: 349894
fast: false

299322
value: 0.0
type: LocalParameter

289347
kinetic law: 394466
product: 394453
reversible: false
notes: GENE_ASSOCIATION: ( ( YKR058W and YLR258W ) or ( YKR058W and YFR015C ) or ( YJL137C and YFR015C ) or ( YJL137C and YLR258W ) ) PROTEIN_ASSOCIATION: ( Glg1 and Gsy2 ) or ( Glg1 and Gsy1 ) or ( Glg2 and Gsy1 ) or ( Glg2 and Gsy2 ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.11
type: Reaction
product: 394427
fast: false
name: R_glycogen_synthase__UDPGlc_
product: 394440
reactant: 394414

421234
stoichiometry: 0.01
species: 285919
type: SpeciesReference

393005
stoichiometry: 0.05
species: 286099
type: SpeciesReference

293364
value: 0.0
type: LocalParameter

428870
stoichiometry: 1.0
species: 284702
type: SpeciesReference

302008
value: 999999.0
type: LocalParameter

364923
stoichiometry: 1.0
species: 284025
type: SpeciesReference

288268
product: 369799
fast: false
product: 369812
type: Reaction
notes: GENE_ASSOCIATION: YKL216W PROTEIN_ASSOCIATION: Ura1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.3.3.1
kinetic law: 369824
reversible: false
reactant: 369787
name: R_dihydoorotic_acid_dehydrogenase__irreversible_
reactant: 369775

287719
notes: GENE_ASSOCIATION: YBR034C PROTEIN_ASSOCIATION: Hmt1 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS:
product: 357510
reactant: 357462
type: Reaction
fast: false
reversible: false
product: 357486
reactant: 357474
product: 357498
kinetic law: 357522
name: R_hnRNP_arginine_N_methyltransferase

404674
stoichiometry: 1.0
species: 284757
type: SpeciesReference

293252
value: 0.0
type: LocalParameter

293365
value: 0.0
type: LocalParameter

298373
value: 0.0
type: LocalParameter

288322
reactant: 370912
product: 370948
product: 370936
product: 370924
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.7.1.24
reactant: 370900
name: R_dephospho_CoA_kinase__mitochondrial
reversible: false
fast: false
type: Reaction
kinetic law: 370961

288536
kinetic law: 374995
product: 374983
reactant: 374971
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Adenosine_exchange
type: Reaction

382188
stoichiometry: 1.0
species: 284166
type: SpeciesReference

288953
kinetic law: 380051
product: 380039
reactant: 380027
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Xanthosine_exchange
type: Reaction

285661
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

358414
stoichiometry: 1.0
species: 284633
type: SpeciesReference

299327
value: 999999.0
type: LocalParameter

289239
reactant: 390965
product: 391001
reversible: false
product: 390977
type: Reaction
name: R_Glycolipid_1_2_alpha_D_mannosyltransferase__Golgi_apparatus
notes: GENE_ASSOCIATION: ( YDR483W or YOR099W or YKR061W or YBR205W or YBR199W or YNL029C or YPL053C or YJL139C ) PROTEIN_ASSOCIATION: ( Kre2-g ) or ( Ktr1-g ) or ( Ktr2-g ) or ( Ktr3-g ) or ( Ktr4-g ) or ( Ktr5-g ) or ( Ktr6-g ) or ( Yur1-g ) SUBSYSTEM: S_Glycoprotein_Metabolism PROTEIN_CLASS: 2.4.1.131
product: 390989
kinetic law: 391014
reactant: 390953
fast: false

288680
kinetic law: 376734
product: 376722
reactant: 376710
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Glucose_exchange
type: Reaction

428118
stoichiometry: 1.0
species: 286390
type: SpeciesReference

283320
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Hydroxy_L_threonine_C4H9NO4
type: Species

390227
stoichiometry: 1.0
species: 284787
type: SpeciesReference

292136
value: -999999.0
type: LocalParameter

291056
value: 999999.0
type: LocalParameter

303275
value: -999999.0
type: LocalParameter

357702
stoichiometry: 1.0
species: 283803
type: SpeciesReference

380522
stoichiometry: 1.0
species: 284778
type: SpeciesReference

357354
stoichiometry: 1.0
species: 284790
type: SpeciesReference

298372
value: 999999.0
type: LocalParameter

379482
stoichiometry: 1.0
species: 286183
type: SpeciesReference

384384
stoichiometry: 8.0
species: 284025
type: SpeciesReference

289025
product: 381403
kinetic law: 381415
fast: false
type: Reaction
reactant: 381367
product: 381391
reactant: 381355
reversible: true
name: R_fatty_acyl_ACP_hydrolase
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 3.1.2.14
product: 381379

425640
stoichiometry: 1.0
species: 285796
type: SpeciesReference

435646
stoichiometry: 0.1
species: 286402
type: SpeciesReference

301674
value: 0.0
type: LocalParameter

292135
value: 0.0
type: LocalParameter

291057
value: 0.0
type: LocalParameter

290897
value: 0.0
type: LocalParameter

293669
value: -0.46209
type: LocalParameter

285517
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

303274
value: 0.0
type: LocalParameter

293367
value: 999999.0
type: LocalParameter

293254
value: 0.0
type: LocalParameter

298375
value: 0.0
type: LocalParameter

287827
fast: false
notes: GENE_ASSOCIATION: ( YBR127C and YDL185W and YEL027W and YEL051W and YGR020C and YHR026W and YHR039C-A and YKL080W and YLR447C and YOR270C and YOR332W and YPL234C and YPR036W ) PROTEIN_ASSOCIATION: Hatp-v SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 3.6.3.14
reactant: 359978
product: 360015
type: Reaction
name: R_ATP_synthase__vacuole
kinetic law: 360052
reactant: 359990
product: 360040
reversible: false
reactant: 360003
product: 360027

301678
value: -0.011879
type: LocalParameter

355532
stoichiometry: 1.0
species: 286474
type: SpeciesReference

299325
value: -0.011879
type: LocalParameter

289237
reactant: 390905
reactant: 390893
product: 390929
product: 390917
reversible: true
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
kinetic law: 390941
type: Reaction
name: R_fumarate_reversible_transport_via_symport

369533
stoichiometry: 1.0
species: 284205
type: SpeciesReference

391098
stoichiometry: 1.0
species: 284577
type: SpeciesReference

411232
stoichiometry: 1.0
species: 285294
type: SpeciesReference

291054
value: 0.0
type: LocalParameter

292138
value: 999999.0
type: LocalParameter

344009
stoichiometry: 1.0
species: 284787
type: SpeciesReference

418418
stoichiometry: 1.0
species: 285592
type: SpeciesReference

298376
value: 0.0
type: LocalParameter

415139
stoichiometry: 1.0
species: 284562
type: SpeciesReference

395410
stoichiometry: 1.0
species: 284757
type: SpeciesReference

288325
kinetic law: 371009
product: 370997
product: 370985
reactant: 370973
notes: GENE_ASSOCIATION: YKL152C PROTEIN_ASSOCIATION: Gpm1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS:
fast: false
reversible: true
name: R_Diphosphoglyceromutase
type: Reaction

288539
kinetic law: 375031
product: 375019
reactant: 375007
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_Oxoglutarate_exchange
type: Reaction

293255
value: 0.0
type: LocalParameter

388008
stoichiometry: 2.0
species: 285421
type: SpeciesReference

404783
stoichiometry: 1.0
species: 284787
type: SpeciesReference

289023
kinetic law: 381343
product: 381331
reactant: 381319
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport
type: Reaction

301677
value: 0.0
type: LocalParameter

299479
value: 0.0
type: LocalParameter

285664
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

299326
value: 0.0
type: LocalParameter

283911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ceramide_1__Sphinganinen_C260__C44H89NO3
type: Species

288683
kinetic law: 376771
product: 376759
reactant: 376747
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Glutamine_exchange
type: Reaction

303276
value: 999999.0
type: LocalParameter

290895
value: 999999.0
type: LocalParameter

440781
stoichiometry: 1.0
species: 283032
type: SpeciesReference

291055
value: -999999.0
type: LocalParameter

363652
stoichiometry: 1.0
species: 284052
type: SpeciesReference

412186
stoichiometry: 0.01
species: 285348
type: SpeciesReference

293369
value: 0.0
type: LocalParameter

288758
kinetic law: 377689
product: 377677
reactant: 377665
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_K_exchange
type: Reaction

400010
stoichiometry: 1.0
species: 284823
type: SpeciesReference

421125
stoichiometry: 1.0
species: 284385
type: SpeciesReference

346464
stoichiometry: 1.0
species: 284766
type: SpeciesReference

294497
value: -999999.0
type: LocalParameter

384072
stoichiometry: 7.0
species: 284808
type: SpeciesReference

427998
stoichiometry: 1.0
species: 284172
type: SpeciesReference

298378
value: 999999.0
type: LocalParameter

303279
value: 0.0
type: LocalParameter

284852
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

397609
stoichiometry: 1.0
species: 284702
type: SpeciesReference

387828
stoichiometry: 1.0
species: 285529
type: SpeciesReference

290892
value: 0.0
type: LocalParameter

289029
kinetic law: 381547
reactant: 381487
product: 381523
reactant: 381475
reversible: false
fast: false
notes: GENE_ASSOCIATION: ( YPL147W and YKL188C ) PROTEIN_ASSOCIATION: ( Pxa1-p and Pxa2-p ) SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
name: R_fatty_acyl_CoA_transport_via_ABC_system
product: 381511
type: Reaction
product: 381535
reactant: 381463
product: 381499

299476
value: 0.0
type: LocalParameter

295172
value: 0.0
type: LocalParameter

292847
value: 0.0
type: LocalParameter

287713
name: R_L_arganine_reversible_transport_via_proton_symport
kinetic law: 357390
product: 357366
notes: GENE_ASSOCIATION: ( YKR039W or YEL063C or YNL270C ) PROTEIN_ASSOCIATION: ( Gap1 ) or ( Can1 ) or ( Alp1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
product: 357378
reversible: true
type: Reaction
fast: false
reactant: 357354
reactant: 357342

288533
kinetic law: 374958
product: 374946
reactant: 374934
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Adenine_exchange
type: Reaction

288686
kinetic law: 376808
product: 376796
reactant: 376783
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Glutamate_exchange
type: Reaction

288956
kinetic law: 380088
product: 380075
reactant: 380063
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Xylose_exchange
type: Reaction

294496
value: 0.0
type: LocalParameter

298377
value: 0.0
type: LocalParameter

417490
stoichiometry: 1.0
species: 286225
type: SpeciesReference

303278
value: 0.0
type: LocalParameter

372049
stoichiometry: 2.0
species: 284463
type: SpeciesReference

290893
value: -999999.0
type: LocalParameter

434548
stoichiometry: 1.0
species: 285405
type: SpeciesReference

282962
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__S__2_Aceto_2_hydroxybutanoate_C6H9O4
type: Species

393984
stoichiometry: 1.0
species: 284657
type: SpeciesReference

293665
value: 0.0
type: LocalParameter

290780
reactant: 440793
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS:
name: R_2_keto_4_methylthiobutyrate_transamination
product: 440805
type: Reaction
kinetic law: 440830
product: 440817
reactant: 440781
reversible: false

292131
value: 0.0
type: LocalParameter

301670
value: 0.0
type: LocalParameter

295173
value: 0.0
type: LocalParameter

299477
value: 0.0
type: LocalParameter

299473
value: -999999.0
type: LocalParameter

287710
fast: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
reversible: true
reactant: 357281
product: 357306
product: 357318
kinetic law: 357330
reactant: 357294
name: R_arginine_mitochondrial_transport_via_proton_symport
type: Reaction

362156
stoichiometry: 1.0
species: 283920
type: SpeciesReference

427887
stoichiometry: 1.0
species: 285913
type: SpeciesReference

422609
stoichiometry: 0.01
species: 285892
type: SpeciesReference

436348
stoichiometry: 1.0
species: 286240
type: SpeciesReference

293250
value: 0.0
type: LocalParameter

288959
kinetic law: 380124
product: 380112
reactant: 380100
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Xylitol_exchange
type: Reaction

285514
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Octanoyl_ACP__n_C80ACP__C19H35N2O8PRS
type: Species

404372
stoichiometry: 1.0
species: 284993
type: SpeciesReference

390011
stoichiometry: 1.0
species: 284412
type: SpeciesReference

301673
value: 999999.0
type: LocalParameter

421814
stoichiometry: 1.0
species: 283830
type: SpeciesReference

285667
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

403137
stoichiometry: 1.0
species: 283647
type: SpeciesReference

283914
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_2__Phytosphingosinen_C240__C42H85NO4
type: Species

299329
value: 0.0
type: LocalParameter

289027
kinetic law: 381451
product: 381439
reactant: 381427
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acyl_ACP_mitochondrial_transport
type: Reaction

403817
stoichiometry: 1.0
species: 286315
type: SpeciesReference

290890
value: 0.0
type: LocalParameter

384953
stoichiometry: 3.0
species: 285406
type: SpeciesReference

299474
value: 999999.0
type: LocalParameter

352406
stoichiometry: 1.0
species: 284787
type: SpeciesReference

292848
value: -999999.0
type: LocalParameter

348711
stoichiometry: 1.0
species: 284016
type: SpeciesReference

391617
stoichiometry: 1.0
species: 284757
type: SpeciesReference

287824
product: 359941
reversible: false
product: 359929
type: Reaction
notes: GENE_ASSOCIATION: ( ( Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDL181W and YDR298C and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W ) or ( Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDL181W and YDR298C and YDR322C-A and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YOL077W-A and YPL078C and YPL271W and YPR020W ) ) PROTEIN_ASSOCIATION: ( Atps1-m ) or ( Atps2-m ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 3.6.3.14
reactant: 359892
kinetic law: 359966
name: R_ATP_synthase__mitochondrial
fast: false
product: 359953
reactant: 359904
reactant: 359916

293667
value: 0.0
type: LocalParameter

443259
stoichiometry: 0.0066
species: 284058
type: SpeciesReference

292133
value: 0.033364
type: LocalParameter

429934
stoichiometry: 1.0
species: 283992
type: SpeciesReference

288115
product: 366465
fast: false
product: 366477
product: 366453
reversible: false
kinetic law: 366489
reactant: 366429
name: R_cysteine_synthase
type: Reaction
notes: GENE_ASSOCIATION: YGR012W PROTEIN_ASSOCIATION: Csy1 SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS:
reactant: 366441

419070
stoichiometry: 1.0
species: 284787
type: SpeciesReference

406885
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298180
value: 0.0
type: LocalParameter

298293
value: 0.0
type: LocalParameter

293829
value: 0.0
type: LocalParameter

301467
value: 0.0
type: LocalParameter

425436
stoichiometry: 1.0
species: 285640
type: SpeciesReference

293683
value: 999999.0
type: LocalParameter

301466
value: 999999.0
type: LocalParameter

284433
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_fecosterol_C28H46O
type: Species

288893
kinetic law: 379326
product: 379314
reactant: 379302
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Spermine_exchange
type: Reaction

292117
value: 0.0
type: LocalParameter

283593
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Adenosine_C10H13N5O4
type: Species

359929
stoichiometry: 1.0
species: 283836
type: SpeciesReference

385304
stoichiometry: 1.0
species: 285219
type: SpeciesReference

443644
stoichiometry: 0.02
species: 286057
type: SpeciesReference

421694
stoichiometry: 1.0
species: 283233
type: SpeciesReference

303296
value: 0.0
type: LocalParameter

292893
value: 0.0
type: LocalParameter

434572
stoichiometry: 2.0
species: 284481
type: SpeciesReference

428411
stoichiometry: 1.0
species: 285565
type: SpeciesReference

298294
value: 999999.0
type: LocalParameter

298181
value: -0.004158
type: LocalParameter

288788
kinetic law: 378054
product: 378042
reactant: 378030
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Melibiose_exchange
type: Reaction

400892
stoichiometry: 1.0
species: 284757
type: SpeciesReference

286180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Thiamin_C12H17N4OS
type: Species

419130
stoichiometry: 1.0
species: 284787
type: SpeciesReference

351781
stoichiometry: 1.0
species: 283635
type: SpeciesReference

284547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Glucosamine_6_phosphate_C6H13NO8P
type: Species

376614
stoichiometry: 1.0
species: 286756
type: SpeciesReference

345969
stoichiometry: 1.0
species: 283203
type: SpeciesReference

303297
value: 999999.0
type: LocalParameter

292892
value: 0.0
type: LocalParameter

353212
stoichiometry: 1.0
species: 283665
type: SpeciesReference

352634
stoichiometry: 1.0
species: 283647
type: SpeciesReference

363290
stoichiometry: 1.0
species: 285487
type: SpeciesReference

293827
value: 999999.0
type: LocalParameter

283707
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_S_Adenosyl_4_methylthio_2_oxobutanoate_C15H19N5O6S
type: Species

289211
fast: false
reversible: false
reactant: 389999
notes: GENE_ASSOCIATION: YEL047C PROTEIN_ASSOCIATION: Frds1 SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS: 1.3.99.1
kinetic law: 390047
product: 390035
type: Reaction
reactant: 390011
product: 390023
name: R_fumarate_reductase__cytosolicmitochondrial

436615
stoichiometry: 1.0
species: 286189
type: SpeciesReference

420339
stoichiometry: 1.0
species: 285751
type: SpeciesReference

290550
kinetic law: 433262
product: 433238
reversible: false
type: Reaction
reactant: 433213
fast: false
name: R_sirohydrochlorin_ferrochetalase
reactant: 433226
notes: GENE_ASSOCIATION: YBR213W PROTEIN_ASSOCIATION: Met8 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS:
product: 433250

284544
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucosamine_6_phosphate_C6H13NO8P
type: Species

300800
value: 0.0
type: LocalParameter

300913
value: 0.0
type: LocalParameter

302299
value: 0.0
type: LocalParameter

288112
reactant: 366357
kinetic law: 366417
reversible: false
notes: GENE_ASSOCIATION: ( ( ( Q0105 and YBL045C and YDR529C and YEL024W and YFR033C and YGR183C and YHR001W-A and YJL166W and YOR065W and YPR191W ) and YEL039C ) or ( ( Q0105 and YBL045C and YDR529C and YEL024W and YFR033C and YGR183C and YHR001W-A and YJL166W and YOR065W and YPR191W ) and YJR048W ) ) PROTEIN_ASSOCIATION: ( Cbc1-m and Cyc7-m ) or ( Cbc1-m and Cyc1-m ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.10.2.2
name: R_ubiquinol_6_cytochrome_c_reductase
reactant: 366369
fast: false
reactant: 366345
type: Reaction
product: 366393
product: 366405
product: 366381

407904
stoichiometry: 1.0
species: 285421
type: SpeciesReference

369996
stoichiometry: 1.0
species: 282984
type: SpeciesReference

430199
stoichiometry: 1.0
species: 285943
type: SpeciesReference

427052
stoichiometry: 1.0
species: 285700
type: SpeciesReference

400543
stoichiometry: 1.0
species: 283830
type: SpeciesReference

298292
value: 0.0
type: LocalParameter

288890
kinetic law: 379290
product: 379278
reactant: 379266
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Spermidine_exchange
type: Reaction

293680
value: 0.0
type: LocalParameter

303295
value: 0.0
type: LocalParameter

300912
value: 0.0
type: LocalParameter

361091
stoichiometry: 1.0
species: 286546
type: SpeciesReference

289690
name: R_Inositol_phosphoryceramide_synthase__ceramide_2__26C___yeast_specific
product: 405254
fast: false
reactant: 405218
reactant: 405230
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reversible: false
type: Reaction
product: 405242
kinetic law: 405266

292890
value: 0.0
type: LocalParameter

374971
stoichiometry: 1.0
species: 283596
type: SpeciesReference

292116
value: -0.011879
type: LocalParameter

302298
value: 0.0
type: LocalParameter

301318
value: 0.0
type: LocalParameter

440649
stoichiometry: 1.0
species: 283602
type: SpeciesReference

298297
value: 0.0
type: LocalParameter

440576
stoichiometry: 1.0
species: 283992
type: SpeciesReference

297853
value: 0.0
type: LocalParameter

288340
reactant: 371346
product: 371382
kinetic law: 371394
name: R_2_5_diamino_6_ribosylamino_4_3H__pyrimidinone_5__phosphate_reductase__nadph_
fast: false
reactant: 371334
reactant: 371358
product: 371370
type: Reaction
notes: GENE_ASSOCIATION: YBR153W PROTEIN_ASSOCIATION: Rib7 SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS:
reversible: false

293687
value: 0.0
type: LocalParameter

303292
value: 0.0
type: LocalParameter

286183
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thiamin_C12H17N4OS
type: Species

292897
value: 0.0
type: LocalParameter

375416
stoichiometry: 1.0
species: 286657
type: SpeciesReference

348409
stoichiometry: 1.0
species: 285760
type: SpeciesReference

439096
stoichiometry: 1.0
species: 283179
type: SpeciesReference

299556
value: 0.0
type: LocalParameter

301319
value: 0.0
type: LocalParameter

348554
stoichiometry: 1.0
species: 284787
type: SpeciesReference

414740
stoichiometry: 1.0
species: 284253
type: SpeciesReference

359711
stoichiometry: 1.0
species: 285832
type: SpeciesReference

298298
value: -0.004158
type: LocalParameter

384649
stoichiometry: 1.0
species: 285433
type: SpeciesReference

371687
stoichiometry: 1.0
species: 284307
type: SpeciesReference

288118
reactant: 366501
notes: GENE_ASSOCIATION: YAL012W PROTEIN_ASSOCIATION: Cys3 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.4.1.1
reversible: false
reactant: 366513
name: R_cystathionine_g_lyase
product: 366550
product: 366526
type: Reaction
product: 366538
fast: false
kinetic law: 366562

297852
value: 0.0
type: LocalParameter

302296
value: 0.0
type: LocalParameter

344215
stoichiometry: 1.0
species: 285751
type: SpeciesReference

433286
stoichiometry: 1.0
species: 284787
type: SpeciesReference

283596
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Adenosine_C10H13N5O4
type: Species

388212
stoichiometry: 3.0
species: 284013
type: SpeciesReference

289692
product: 405302
reactant: 405290
fast: false
kinetic law: 405327
name: R_Inositol_phosphorylceramide_synthase__ceramide_3__24C___yeast_specific
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reversible: false
product: 405314
type: Reaction
reactant: 405278

380957
stoichiometry: 1.0
species: 285634
type: SpeciesReference

298299
value: 0.0
type: LocalParameter

284858
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

283704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_S_Adenosylmethioninamine_C14H24N6O3S
type: Species

284430
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_fecosterol_C28H46O
type: Species

369787
stoichiometry: 1.0
species: 285487
type: SpeciesReference

303293
value: 0.0
type: LocalParameter

418563
stoichiometry: 1.0
species: 285550
type: SpeciesReference

299662
value: 0.0
type: LocalParameter

432355
stoichiometry: 1.0
species: 285886
type: SpeciesReference

298295
value: 0.0
type: LocalParameter

422117
stoichiometry: 1.0
species: 285412
type: SpeciesReference

283929
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_2___Sphinganinen_C260OH__C44H89NO4
type: Species

397077
stoichiometry: 1.0
species: 284790
type: SpeciesReference

443790
stoichiometry: 58.70001
species: 284787
type: SpeciesReference

421548
stoichiometry: 1.0
species: 284787
type: SpeciesReference

435392
stoichiometry: 1.0
species: 284781
type: SpeciesReference

373087
stoichiometry: 0.01
species: 284334
type: SpeciesReference

360064
stoichiometry: 1.0
species: 283602
type: SpeciesReference

443416
stoichiometry: 59.276
species: 284757
type: SpeciesReference

292119
value: 999999.0
type: LocalParameter

300917
value: 0.0
type: LocalParameter

302295
value: 0.0
type: LocalParameter

417212
stoichiometry: 1.0
species: 284757
type: SpeciesReference

283599
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Adenosine_C10H13N5O4
type: Species

299558
value: 999999.0
type: LocalParameter

303290
value: 999999.0
type: LocalParameter

284855
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

372352
stoichiometry: 1.0
species: 284328
type: SpeciesReference

358209
stoichiometry: 1.0
species: 283791
type: SpeciesReference

292895
value: 999999.0
type: LocalParameter

293685
value: 0.0
type: LocalParameter

356643
stoichiometry: 1.0
species: 285487
type: SpeciesReference

428833
stoichiometry: 1.0
species: 283002
type: SpeciesReference

299661
value: 0.0
type: LocalParameter

301317
value: 0.031838
type: LocalParameter

435236
stoichiometry: 1.0
species: 286114
type: SpeciesReference

414351
stoichiometry: 1.0
species: 283620
type: SpeciesReference

383975
stoichiometry: 1.0
species: 285433
type: SpeciesReference

288229
kinetic law: 369059
reversible: false
product: 369034
product: 369047
name: R_deoxyguanosine_transport_in_via_proton_symport
reactant: 369022
fast: false
type: Reaction
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reactant: 369010

406656
stoichiometry: 0.01
species: 284870
type: SpeciesReference

357125
stoichiometry: 1.0
species: 283830
type: SpeciesReference

297850
value: 999999.0
type: LocalParameter

300916
value: 0.0
type: LocalParameter

289694
name: R_Inositol_phosphorylceramide_synthase__ceramide_3__26C___yeast_specific
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reversible: false
product: 405363
kinetic law: 405388
product: 405376
type: Reaction
fast: false
reactant: 405339
reactant: 405351

299557
value: 0.0
type: LocalParameter

286186
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Thiamin_monophosphate_C12H16N4O4PS
type: Species

405484
stoichiometry: 1.0
species: 285396
type: SpeciesReference

299665
value: 0.0
type: LocalParameter

401601
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298189
value: 0.0
type: LocalParameter

295094
value: -0.059395
type: LocalParameter

284966
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Iminoaspartate_C4H3NO4
type: Species

376650
stoichiometry: 1.0
species: 286759
type: SpeciesReference

283701
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_S_Adenosyl_L_methionine_C15H23N6O5S
type: Species

302188
value: 999999.0
type: LocalParameter

289584
reactant: 402012
product: 402048
reactant: 402036
product: 402060
reactant: 402024
notes: GENE_ASSOCIATION: YER023W PROTEIN_ASSOCIATION: Pro3 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.2
reversible: false
kinetic law: 402072
fast: false
name: R_L_hydroxyproline_reductase__NADP_
type: Reaction

283488
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_L_Arabinitol_C5H12O5
type: Species

290556
reactant: 433431
kinetic law: 433479
product: 433467
reactant: 433419
fast: false
type: Reaction
product: 433455
name: R_O_succinylhomoserine_lyase__L_cysteine_
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.2.99.9
reversible: false
product: 433443

300806
value: 0.0
type: LocalParameter

400651
stoichiometry: 1.0
species: 284403
type: SpeciesReference

383867
stoichiometry: 7.0
species: 284778
type: SpeciesReference

297857
value: 999999.0
type: LocalParameter

403283
stoichiometry: 1.0
species: 286105
type: SpeciesReference

298188
value: 0.0
type: LocalParameter

299551
value: 999999.0
type: LocalParameter

301314
value: 0.0
type: LocalParameter

293219
value: 0.0
type: LocalParameter

415151
stoichiometry: 1.0
species: 284757
type: SpeciesReference

345739
stoichiometry: 1.0
species: 283185
type: SpeciesReference

299664
value: 0.0
type: LocalParameter

391195
stoichiometry: 1.0
species: 284565
type: SpeciesReference

302187
value: 0.0
type: LocalParameter

375308
stoichiometry: 1.0
species: 286648
type: SpeciesReference

300805
value: 0.0
type: LocalParameter

289798
kinetic law: 409097
product: 409085
reactant: 409073
notes: GENE_ASSOCIATION: YER003C PROTEIN_ASSOCIATION: Pmi40 SUBSYSTEM: S_Fructose_and_Mannose_Metabolism PROTEIN_CLASS: 5.3.1.8
fast: false
reversible: true
name: R_mannose_6_phosphate_isomerase
type: Reaction

373195
stoichiometry: 0.01
species: 284343
type: SpeciesReference

394058
stoichiometry: 1.0
species: 284663
type: SpeciesReference

287992
kinetic law: 363966
product: 363954
reactant: 363942
notes: GENE_ASSOCIATION: YPR060C PROTEIN_ASSOCIATION: Aro7 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 5.4.99.5
fast: false
reversible: false
name: R_chorismate_mutase
type: Reaction

371578
stoichiometry: 1.0
species: 284301
type: SpeciesReference

299550
value: 0.0
type: LocalParameter

293218
value: 0.0
type: LocalParameter

289361
fast: false
product: 394877
reactant: 394865
name: R_L_glutamine_transport_in_via_proton_antiport__vacuolar_
product: 394890
notes: GENE_ASSOCIATION: YJR001W PROTEIN_ASSOCIATION: Avt1-v SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
kinetic law: 394902
reversible: false
reactant: 394853
type: Reaction

390492
stoichiometry: 1.0
species: 282889
type: SpeciesReference

292899
value: 0.0
type: LocalParameter

293794
value: 0.0
type: LocalParameter

285095
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_ITP_C10H11N4O14P3
type: Species

299554
value: 0.0
type: LocalParameter

418455
stoichiometry: 1.0
species: 285751
type: SpeciesReference

290558
product: 433515
product: 433540
product: 433552
type: Reaction
kinetic law: 433564
fast: false
name: R_O_succinylhomoserine_lyase__elimination___reversible
product: 433527
reactant: 433491
reactant: 433503
notes: GENE_ASSOCIATION: YML082W PROTEIN_ASSOCIATION: Cgs1 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.2.99.9
reversible: true

289586
notes: GENE_ASSOCIATION: YHR037W PROTEIN_ASSOCIATION: Put2-m SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12
product: 402121
reactant: 402097
name: R_L_hydroxyproline_dehydrogenase__NAD___mitochondrial
product: 402133
product: 402109
fast: false
reactant: 402084
type: Reaction
kinetic law: 402146
reversible: false

430007
stoichiometry: 1.0
species: 283992
type: SpeciesReference

302186
value: -0.093249
type: LocalParameter

284439
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
type: Species

297855
value: -999999.0
type: LocalParameter

287995
kinetic law: 364014
product: 364002
product: 363990
reactant: 363978
notes: GENE_ASSOCIATION: YGL148W PROTEIN_ASSOCIATION: Aro2 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.3.5
fast: false
reversible: false
name: R_chorismate_synthase
type: Reaction

345521
stoichiometry: 1.0
species: 285436
type: SpeciesReference

288226
notes: GENE_ASSOCIATION: YDR454C PROTEIN_ASSOCIATION: Guk1.1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.7.4.8
reactant: 368950
name: R_deoxyguanylate_kinase__dGMPATP_
kinetic law: 368998
fast: false
product: 368986
type: Reaction
reversible: true
product: 368974
reactant: 368962

442050
stoichiometry: 1.0
species: 286507
type: SpeciesReference

298186
value: 0.047411
type: LocalParameter

295095
value: 0.0
type: LocalParameter

405593
stoichiometry: 1.0
species: 283029
type: SpeciesReference

299666
value: 999999.0
type: LocalParameter

299553
value: 0.0
type: LocalParameter

293793
value: 0.0
type: LocalParameter

386839
stoichiometry: 1.0
species: 284013
type: SpeciesReference

297854
value: 0.0
type: LocalParameter

437585
stoichiometry: 1.0
species: 283992
type: SpeciesReference

288899
kinetic law: 379398
product: 379386
reactant: 379374
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Succinate_exchange
type: Reaction

432463
stoichiometry: 1.0
species: 286018
type: SpeciesReference

293939
value: 0.0
type: LocalParameter

301313
value: 999999.0
type: LocalParameter

289363
notes: GENE_ASSOCIATION: ( YKL146W or YNL101W ) PROTEIN_ASSOCIATION: ( Avt3-v ) or ( Avt4-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
product: 394938
name: R_L_glutamine_transport_out_via_proton_symport__vacuolar
fast: false
reversible: false
kinetic law: 394962
product: 394950
reactant: 394914
type: Reaction
reactant: 394926

293216
value: 0.0
type: LocalParameter

290778
kinetic law: 440769
product: 440757
reactant: 440745
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_UMP_nuclear_transport
type: Reaction

290552
fast: false
product: 433310
reversible: false
notes: GENE_ASSOCIATION: YDR127W PROTEIN_ASSOCIATION: Aro1 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.1.1.25
product: 433322
kinetic law: 433335
type: Reaction
reactant: 433298
reactant: 433286
reactant: 433274
name: R_shikimate_dehydrogenase

292008
value: 0.0
type: LocalParameter

289794
product: 408976
kinetic law: 408988
reversible: true
reactant: 408952
notes: GENE_ASSOCIATION: YLR348C PROTEIN_ASSOCIATION: Dic1-m SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
product: 408964
type: Reaction
name: R_malate_transport__mitochondrial
reactant: 408940
fast: false

419288
stoichiometry: 1.0
species: 285598
type: SpeciesReference

289580
reversible: false
reactant: 401879
type: Reaction
product: 401903
product: 401891
name: R_2_amino_4_hydroxy_6_hydroxymethyldihydropteridine_diphosphokinase__mitochondrial
reactant: 401867
kinetic law: 401928
fast: false
product: 401916
notes: GENE_ASSOCIATION: YNL256W PROTEIN_ASSOCIATION: Fol1-m SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 2.7.6.3

300802
value: 999999.0
type: LocalParameter

289367
reversible: false
reactant: 395047
kinetic law: 395083
fast: false
notes: GENE_ASSOCIATION: YDR300C PROTEIN_ASSOCIATION: Pro1 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.7.2.11
reactant: 395035
product: 395071
name: R_glutamate_5_kinase
product: 395059
type: Reaction

299669
value: 0.085323
type: LocalParameter

288785
kinetic law: 378018
product: 378006
reactant: 377993
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Mannose_exchange
type: Reaction

403841
stoichiometry: 1.0
species: 285023
type: SpeciesReference

437439
stoichiometry: 3.0
species: 284757
type: SpeciesReference

292009
value: -999999.0
type: LocalParameter

301310
value: 0.0
type: LocalParameter

300801
value: -999999.0
type: LocalParameter

435839
stoichiometry: 1.0
species: 286135
type: SpeciesReference

293791
value: 0.0
type: LocalParameter

299668
value: 0.0
type: LocalParameter

285092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Itaconate_C5H4O4
type: Species

289365
product: 394998
notes: GENE_ASSOCIATION: YLR195C PROTEIN_ASSOCIATION: Nmt1 SUBSYSTEM: S_Other_Amino_Acid_Metabolism PROTEIN_CLASS: 2.3.1.97
fast: false
reversible: false
product: 395010
kinetic law: 395022
reactant: 394986
type: Reaction
name: R_glycylpeptide_N_tetradecanoyltransferase
reactant: 394974

298185
value: 0.0
type: LocalParameter

295098
value: 999999.0
type: LocalParameter

412285
stoichiometry: 0.01
species: 285333
type: SpeciesReference

288223
reversible: false
fast: false
name: R_alpha_D_glucoside_glucohydrase
product: 368914
kinetic law: 368938
reactant: 368902
product: 368926
reactant: 368890
type: Reaction
notes: GENE_ASSOCIATION: YJL221C PROTEIN_ASSOCIATION: Fsp2 SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS:

294318
value: 999999.0
type: LocalParameter

352718
stoichiometry: 1.0
species: 286027
type: SpeciesReference

357498
stoichiometry: 1.0
species: 283626
type: SpeciesReference

298290
value: 0.00711
type: LocalParameter

367081
stoichiometry: 1.0
species: 284787
type: SpeciesReference

289582
reactant: 401940
reactant: 401964
reversible: false
reactant: 401952
fast: false
name: R_L_hydroxyproline_reductase__NAD_
product: 401988
kinetic law: 402000
notes: GENE_ASSOCIATION: YER023W PROTEIN_ASSOCIATION: Pro3 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.2
product: 401976
type: Reaction

376504
stoichiometry: 1.0
species: 286747
type: SpeciesReference

292006
value: 0.0
type: LocalParameter

353320
stoichiometry: 1.0
species: 285796
type: SpeciesReference

290554
kinetic law: 433407
product: 433371
reactant: 433347
reactant: 433359
name: R_shikimate_kinase
type: Reaction
reversible: false
product: 433395
notes: GENE_ASSOCIATION: YDR127W PROTEIN_ASSOCIATION: Aro1 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.7.1.71
product: 433383
fast: false

289369
product: 395144
notes: GENE_ASSOCIATION: YJL101C PROTEIN_ASSOCIATION: Gsh1 SUBSYSTEM: S_Other_Amino_Acid_Metabolism PROTEIN_CLASS: 6.3.2.2
reactant: 395108
reversible: false
fast: false
reactant: 395096
product: 395132
reactant: 395120
type: Reaction
kinetic law: 395181
product: 395156
name: R_gamma_glutamylcysteine_synthetase
product: 395169

288782
kinetic law: 377981
product: 377968
reactant: 377956
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Maltose_exchange
type: Reaction

420448
stoichiometry: 1.0
species: 283713
type: SpeciesReference

293936
value: 0.0
type: LocalParameter

425508
stoichiometry: 1.0
species: 285700
type: SpeciesReference

297859
value: 0.0
type: LocalParameter

288896
kinetic law: 379362
product: 379350
reactant: 379338
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Sorbose_exchange
type: Reaction

298182
value: 0.0
type: LocalParameter

409085
stoichiometry: 1.0
species: 284403
type: SpeciesReference

415004
stoichiometry: 1.0
species: 285381
type: SpeciesReference

427634
stoichiometry: 1.0
species: 284757
type: SpeciesReference

283485
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_L_Arabinitol_C5H12O5
type: Species

288220
kinetic law: 368878
product: 368866
reactant: 368854
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_dGDP_nuclear_transport
type: Reaction

430807
stoichiometry: 1.0
species: 285985
type: SpeciesReference

284436
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

284969
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_isobutyl_acetate_C6H12O2
type: Species

284541
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Glucosamine_1_phosphate_C6H13NO8P
type: Species

346561
stoichiometry: 1.0
species: 283311
type: SpeciesReference

298183
value: 999999.0
type: LocalParameter

297858
value: 0.0
type: LocalParameter

396822
stoichiometry: 1.0
species: 285107
type: SpeciesReference

289796
reactant: 409024
notes: GENE_ASSOCIATION: YDL055C PROTEIN_ASSOCIATION: Psa1 SUBSYSTEM: S_Fructose_and_Mannose_Metabolism PROTEIN_CLASS: 2.7.7.13
reactant: 409000
kinetic law: 409061
reversible: false
product: 409048
name: R_mannose_1_phosphate_guanylyltransferase
product: 409036
type: Reaction
fast: false
reactant: 409012

288445
product: 373643
kinetic law: 373667
product: 373631
fast: false
product: 373595
type: Reaction
reactant: 373546
product: 373583
name: R_ergosterol_ester_hydrolase__yeast_specific
product: 373570
product: 373619
product: 373607
reactant: 373558
product: 373655
reversible: false
notes: GENE_ASSOCIATION: ( YKL140W or YLL012W ) PROTEIN_ASSOCIATION: ( Tgl1 ) or ( Yeh1 ) SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:

294467
value: 0.0
type: LocalParameter

289143
product: 387345
type: Reaction
name: R_fatty_acyl_CoA_synthase__n_C180CoA_
product: 387357
fast: false
product: 387320
product: 387369
reactant: 387308
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86
kinetic law: 387381
reactant: 387284
reversible: false
reactant: 387296
reactant: 387272
product: 387333

287851
notes: GENE_ASSOCIATION: YGR286C PROTEIN_ASSOCIATION: Bio2 SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 2.8.1.6
fast: false
product: 360574
kinetic law: 360587
type: Reaction
reversible: true
product: 360562
reactant: 360550
name: R_biotin_synthase
reactant: 360538

427790
stoichiometry: 1.0
species: 285865
type: SpeciesReference

292708
value: 0.0
type: LocalParameter

301533
value: 0.0
type: LocalParameter

299332
value: -0.011879
type: LocalParameter

299446
value: 999999.0
type: LocalParameter

299333
value: 0.0
type: LocalParameter

302191
value: 0.0
type: LocalParameter

293933
value: 999999.0
type: LocalParameter

396109
stoichiometry: 1.0
species: 284805
type: SpeciesReference

303398
value: 0.0
type: LocalParameter

291062
value: 0.0
type: LocalParameter

292017
value: 0.0
type: LocalParameter

291175
value: 0.0
type: LocalParameter

303792
value: 0.0
type: LocalParameter

357895
stoichiometry: 1.0
species: 283713
type: SpeciesReference

293223
value: 0.0
type: LocalParameter

293376
value: 999999.0
type: LocalParameter

428559
stoichiometry: 1.0
species: 285799
type: SpeciesReference

287707
notes: GENE_ASSOCIATION: YHR091C PROTEIN_ASSOCIATION: Msr1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.19
reactant: 357209
fast: false
product: 357245
type: Reaction
product: 357257
name: R_Arginyl_tRNA_synthetase__mitochondrial
reactant: 357221
reversible: false
reactant: 357197
product: 357233
kinetic law: 357269

289359
name: R_L_glutamine_reversible_transport_via_proton_symport
reactant: 394793
kinetic law: 394841
reversible: true
type: Reaction
product: 394829
product: 394817
fast: false
reactant: 394805
notes: GENE_ASSOCIATION: ( YKR039W or YCL025C or YDR508C or YPL265W ) PROTEIN_ASSOCIATION: ( Gap1 ) or ( Agp1 ) or ( Gnp1 ) or ( Dip5 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:

299334
value: 999999.0
type: LocalParameter

303397
value: 0.0
type: LocalParameter

291063
value: -999999.0
type: LocalParameter

290774
reversible: true
fast: false
reactant: 440625
type: Reaction
name: R_UMP_kinase
product: 440661
reactant: 440637
product: 440649
kinetic law: 440673
notes: GENE_ASSOCIATION: YKL024C PROTEIN_ASSOCIATION: Ura6 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.14

303791
value: 0.0
type: LocalParameter

291176
value: 0.0
type: LocalParameter

400434
stoichiometry: 1.0
species: 283602
type: SpeciesReference

293373
value: 0.0
type: LocalParameter

294328
value: -999999.0
type: LocalParameter

407213
stoichiometry: 1.0
species: 285143
type: SpeciesReference

396676
stoichiometry: 1.0
species: 286438
type: SpeciesReference

292706
value: 999999.0
type: LocalParameter

289145
fast: false
product: 387465
kinetic law: 387514
name: R_fatty_acid_synthase__n_C181_
product: 387477
product: 387453
notes: GENE_ASSOCIATION: YJL196C PROTEIN_ASSOCIATION: Elo1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reactant: 387393
product: 387489
reactant: 387441
reversible: false
reactant: 387417
product: 387502
type: Reaction
reactant: 387405
reactant: 387429

299448
value: 0.0
type: LocalParameter

293931
value: 0.0
type: LocalParameter

301530
value: 0.0
type: LocalParameter

418888
stoichiometry: 1.0
species: 284618
type: SpeciesReference

375524
stoichiometry: 1.0
species: 286666
type: SpeciesReference

288442
reactant: 373436
type: Reaction
reversible: false
reactant: 373424
name: R_Acyl_CoAergosterol_acyltransferase__yeast_specific
product: 373510
notes: GENE_ASSOCIATION: ( YCR048W or YNR019W ) PROTEIN_ASSOCIATION: ( Are1 ) or ( Are2 ) SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
kinetic law: 373534
fast: false
reactant: 373473
reactant: 373461
reactant: 373497
reactant: 373485
product: 373522
reactant: 373448

429341
stoichiometry: 1.0
species: 283602
type: SpeciesReference

292015
value: 0.715712
type: LocalParameter

291064
value: 999999.0
type: LocalParameter

293789
value: 0.0
type: LocalParameter

293374
value: 0.0
type: LocalParameter

293221
value: 999999.0
type: LocalParameter

294327
value: 0.0
type: LocalParameter

287854
name: R_C_14_sterol_reductase
type: Reaction
product: 360650
notes: GENE_ASSOCIATION: YNL280C PROTEIN_ASSOCIATION: Erg24 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
reactant: 360600
reactant: 360613
reactant: 360625
kinetic law: 360663
product: 360637
reversible: false
fast: false

292818
value: 0.0
type: LocalParameter

422008
stoichiometry: 0.01
species: 285715
type: SpeciesReference

287197
reactant: 346367
reactant: 346343
kinetic law: 346439
product: 346403
product: 346427
reactant: 346379
product: 346415
name: R_4_hydroxybenzoyl_CoA_formation
reversible: false
reactant: 346355
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
fast: false
type: Reaction
product: 346391

288560
kinetic law: 375284
product: 375272
reactant: 375259
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Arginine_exchange
type: Reaction

285541
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_octadecenoate__n_C181__C18H33O2
type: Species

299449
value: -0.055472
type: LocalParameter

302190
value: 0.0
type: LocalParameter

289147
name: R_fatty_acyl_ACP_synthase__n_C181ACP___mitochondrial
fast: false
reactant: 387575
product: 387623
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
reactant: 387538
reactant: 387551
reversible: false
reactant: 387526
reactant: 387563
product: 387599
product: 387611
product: 387635
kinetic law: 387647
product: 387587
type: Reaction

299336
value: 0.0
type: LocalParameter

293932
value: -999999.0
type: LocalParameter

291178
value: 999999.0
type: LocalParameter

291065
value: 0.0
type: LocalParameter

290776
type: Reaction
notes: GENE_ASSOCIATION: YKL024C PROTEIN_ASSOCIATION: Ura6-n SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS:
name: R_UMP_kinase__nuclear
product: 440721
fast: false
reactant: 440685
product: 440709
reversible: true
reactant: 440697
kinetic law: 440733

303793
value: 0.0
type: LocalParameter

303395
value: 999999.0
type: LocalParameter

283482
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Aminoacetone_C3H8NO
type: Species

285089
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Itaconyl_CoA_C26H35N7O19P3S
type: Species

288566
kinetic law: 375356
product: 375344
reactant: 375332
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Aspartate_exchange
type: Reaction

385911
stoichiometry: 3.0
species: 284796
type: SpeciesReference

298072
value: -999999.0
type: LocalParameter

362011
stoichiometry: 1.0
species: 283884
type: SpeciesReference

289576
kinetic law: 401782
product: 401770
reactant: 401757
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_Hydroxymethylglutaryl_CoA_reversible_mitochondrial_transport
type: Reaction

293371
value: 6.33E-4
type: LocalParameter

293787
value: 999999.0
type: LocalParameter

303796
value: 0.0
type: LocalParameter

300809
value: 0.0
type: LocalParameter

443139
stoichiometry: 0.4588
species: 283659
type: SpeciesReference

391737
stoichiometry: 1.0
species: 284612
type: SpeciesReference

292013
value: 0.0
type: LocalParameter

302195
value: 999999.0
type: LocalParameter

284975
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_isobutyl_alcohol_C4H10O
type: Species

292704
value: 0.0
type: LocalParameter

421935
stoichiometry: 1.0
species: 283233
type: SpeciesReference

289209
kinetic law: 389986
product: 389974
reactant: 389962
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_farnesyl_diphosphate_transport__mitochondrial_
type: Reaction

298071
value: -0.003366
type: LocalParameter

352862
stoichiometry: 1.0
species: 284799
type: SpeciesReference

294321
value: 0.0
type: LocalParameter

293227
value: 0.0
type: LocalParameter

357041
stoichiometry: 1.0
species: 283974
type: SpeciesReference

303795
value: 999999.0
type: LocalParameter

285547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

292703
value: 0.0
type: LocalParameter

390155
stoichiometry: 1.0
species: 285796
type: SpeciesReference

400119
stoichiometry: 1.0
species: 284824
type: SpeciesReference

289149
fast: false
type: Reaction
product: 387719
reactant: 387659
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
kinetic law: 387779
reversible: false
name: R_fatty_acyl_ACP_synthase__n_C182ACP___mitochondrial
product: 387743
product: 387767
reactant: 387683
product: 387731
reactant: 387695
reactant: 387671
product: 387755
reactant: 387707

290770
product: 440499
notes: GENE_ASSOCIATION: YBR018C PROTEIN_ASSOCIATION: Gal7 SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 2.7.7.12
reversible: true
type: Reaction
product: 440512
name: R_UDPglucose__hexose_1_phosphate_uridylyltransferase
fast: false
reactant: 440473
kinetic law: 440525
reactant: 440486

299330
value: 0.0
type: LocalParameter

412065
stoichiometry: 0.01
species: 285342
type: SpeciesReference

294324
value: 0.0019
type: LocalParameter

288677
kinetic law: 376698
product: 376686
reactant: 376674
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Glycolaldehyde_exchange
type: Reaction

346343
stoichiometry: 1.0
species: 284016
type: SpeciesReference

287998
kinetic law: 364063
product: 364051
product: 364039
reactant: 364026
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Quinone_Biosynthesis PROTEIN_CLASS:
fast: false
reversible: false
name: R_Chorismate_pyruvate_lyase
type: Reaction

351137
stoichiometry: 1.0
species: 284568
type: SpeciesReference

303799
value: -0.08434
type: LocalParameter

287704
product: 357173
fast: false
type: Reaction
reactant: 357113
reactant: 357125
reversible: false
name: R_Arginyl_tRNA_synthetase
reactant: 357137
product: 357161
kinetic law: 357185
notes: GENE_ASSOCIATION: YDR341C PROTEIN_ASSOCIATION: Msr2 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.19
product: 357149

289578
product: 401843
reactant: 401794
name: R_hydroxymethylpyrimidine_kinase__ATP_
reactant: 401806
product: 401831
product: 401819
kinetic law: 401855
fast: false
notes: GENE_ASSOCIATION: ( YOL055C or YPL258C or YPR121W ) PROTEIN_ASSOCIATION: ( Thi20 ) or ( Thi21 ) or ( Thi22 ) SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.7.1.49
reversible: false
type: Reaction

287857
fast: false
product: 360754
reactant: 360702
notes: GENE_ASSOCIATION: ( YMR015C and YHR042W ) PROTEIN_ASSOCIATION: ( Erg5 and Ncp1 ) SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
reactant: 360689
product: 360741
reactant: 360715
type: Reaction
product: 360728
name: R_C_22_sterol_desaturase__NADP_
kinetic law: 360766
reversible: false
reactant: 360676

303798
value: 0.0
type: LocalParameter

288563
kinetic law: 375320
product: 375308
reactant: 375296
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Asparagine_exchange
type: Reaction

285086
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Isopentenyl_diphosphate_C5H9O7P2
type: Species

285544
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

292011
value: 999999.0
type: LocalParameter

302193
value: 0.0
type: LocalParameter

293225
value: 4.281244
type: LocalParameter

348205
stoichiometry: 1.0
species: 283518
type: SpeciesReference

369836
stoichiometry: 1.0
species: 284220
type: SpeciesReference

291060
value: 0.0
type: LocalParameter

285658
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
type: Species

284972
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isobutyl_acetate_C6H12O2
type: Species

369302
stoichiometry: 1.0
species: 285436
type: SpeciesReference

290772
kinetic law: 440613
reversible: true
reactant: 440564
fast: false
type: Reaction
product: 440589
product: 440576
reactant: 440552
name: R_Ureidoglycolate_hydrolase
notes: GENE_ASSOCIATION: YIR032C PROTEIN_ASSOCIATION: Dal3 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 3.5.3.19
reactant: 440538
product: 440601

393863
stoichiometry: 1.0
species: 284532
type: SpeciesReference

380801
stoichiometry: 1.0
species: 285772
type: SpeciesReference

344628
stoichiometry: 1.0
species: 283038
type: SpeciesReference

292701
value: 0.0
type: LocalParameter

302194
value: 0.0
type: LocalParameter

289205
kinetic law: 389913
product: 389901
reactant: 389889
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_formate_transport_via_diffusion
type: Reaction

283926
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_2___Sphinganinen_C240OH__C42H85NO4
type: Species

285655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

344738
stoichiometry: 1.0
species: 283053
type: SpeciesReference

403998
stoichiometry: 1.0
species: 284805
type: SpeciesReference

421826
stoichiometry: 1.0
species: 282905
type: SpeciesReference

289684
kinetic law: 405086
reactant: 405037
name: R_Inositol_phosphorylceramide_synthase__ceramide_1__24C___yeast_specific
fast: false
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
type: Reaction
reversible: false
product: 405062
reactant: 405049
product: 405074

383140
stoichiometry: 1.0
species: 283713
type: SpeciesReference

288331
kinetic law: 371167
product: 371143
fast: false
reactant: 371130
type: Reaction
name: R_2_dehydropantoate_2_reductase
reversible: false
reactant: 371106
product: 371155
reactant: 371118
notes: GENE_ASSOCIATION: YHR063C PROTEIN_ASSOCIATION: Pan5 SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 1.1.1.169

300918
value: 999999.0
type: LocalParameter

409411
stoichiometry: 1.0
species: 284013
type: SpeciesReference

404360
stoichiometry: 1.0
species: 283992
type: SpeciesReference

436336
stoichiometry: 2.0
species: 284778
type: SpeciesReference

288947
kinetic law: 379978
product: 379966
reactant: 379954
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Valine_exchange
type: Reaction

298076
value: 0.12312
type: LocalParameter

286177
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Tetrahydrofolyl_Glu_2__C24H27N8O9
type: Species

362168
stoichiometry: 1.0
species: 283923
type: SpeciesReference

292121
value: 0.0
type: LocalParameter

293821
value: 0.0
type: LocalParameter

292812
value: -999999.0
type: LocalParameter

365720
stoichiometry: 1.0
species: 284049
type: SpeciesReference

293679
value: 0.0
type: LocalParameter

282996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Dehydropantoate_C6H9O4
type: Species

443247
stoichiometry: 1.0E-6
species: 284013
type: SpeciesReference

363398
stoichiometry: 1.0
species: 283929
type: SpeciesReference

289686
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 405134
kinetic law: 405146
reversible: false
name: R_Inositol_phosphorylceramide_synthase__ceramide_1__26C___yeast_specific
product: 405122
reactant: 405098
fast: false
reactant: 405110
type: Reaction

427850
stoichiometry: 1.0
species: 285898
type: SpeciesReference

426485
stoichiometry: 1.0
species: 284787
type: SpeciesReference

352418
stoichiometry: 1.0
species: 285264
type: SpeciesReference

298289
value: 0.0
type: LocalParameter

289207
kinetic law: 389950
product: 389937
reactant: 389925
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_formate_mitochondrial_transport
type: Reaction

292811
value: -0.00198
type: LocalParameter

374826
stoichiometry: 1.0
species: 283500
type: SpeciesReference

439761
stoichiometry: 1.0
species: 286423
type: SpeciesReference

282999
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Deoxy_D_glucose_6_phosphate_C6H11O8P
type: Species

284864
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Heme_O_C49H56FeN4O5
type: Species

348856
stoichiometry: 1.0
species: 284787
type: SpeciesReference

384084
stoichiometry: 6.0
species: 284754
type: SpeciesReference

440793
stoichiometry: 1.0
species: 284618
type: SpeciesReference

294461
value: 999999.0
type: LocalParameter

366574
stoichiometry: 1.0
species: 284064
type: SpeciesReference

301539
value: 0.0
type: LocalParameter

298074
value: 0.0
type: LocalParameter

363688
stoichiometry: 1.0
species: 285796
type: SpeciesReference

402607
stoichiometry: 1.0
species: 284936
type: SpeciesReference

293677
value: 0.0
type: LocalParameter

289688
reactant: 405170
kinetic law: 405206
reactant: 405158
notes: GENE_ASSOCIATION: YKL004W PROTEIN_ASSOCIATION: Aur1 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
product: 405182
fast: false
reversible: false
type: Reaction
name: R_Inositol_phosphorylceramide_synthase__ceramide_2__24C___yeast_specific
product: 405194

285505
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Oxaloacetate_C4H2O5
type: Species

287701
reactant: 357017
product: 357077
product: 357065
fast: false
type: Reaction
product: 357089
reversible: true
kinetic law: 357101
reactant: 357041
name: R_argininosuccinate_synthase__reversible
notes: GENE_ASSOCIATION: YOL058W PROTEIN_ASSOCIATION: Arg1 SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 6.3.4.5
reactant: 357029
product: 357053

288569
kinetic law: 375392
product: 375380
reactant: 375368
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R__R_R__2_3_Butanediol_exchange
type: Reaction

298073
value: 999999.0
type: LocalParameter

288944
kinetic law: 379942
product: 379930
reactant: 379918
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Uridine_exchange
type: Reaction

288674
kinetic law: 376662
product: 376650
reactant: 376638
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Glucosamine_6_phosphate_exchange
type: Reaction

301538
value: 999999.0
type: LocalParameter

298287
value: 999999.0
type: LocalParameter

395591
stoichiometry: 1.0
species: 284757
type: SpeciesReference

288121
kinetic law: 366634
name: R_cystathionine_b_lyase
fast: false
reactant: 366574
notes: GENE_ASSOCIATION: YFR055W PROTEIN_ASSOCIATION: Cys1 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.4.1.8
reversible: false
reactant: 366586
type: Reaction
product: 366610
product: 366598
product: 366622

291171
value: 0.0
type: LocalParameter

409556
stoichiometry: 1.0
species: 285502
type: SpeciesReference

400324
stoichiometry: 1.0
species: 284484
type: SpeciesReference

303289
value: -999999.0
type: LocalParameter

291066
value: 0.0
type: LocalParameter

292126
value: -999999.0
type: LocalParameter

301463
value: 0.0
type: LocalParameter

299337
value: 0.0
type: LocalParameter

293824
value: -999999.0
type: LocalParameter

282993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Dehydropantoate_C6H9O4
type: Species

299441
value: 0.0
type: LocalParameter

285502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Oxaloacetate_C4H2O5
type: Species

288449
reversible: false
reactant: 373811
product: 373859
product: 373835
reactant: 373823
kinetic law: 373871
type: Reaction
product: 373847
notes: GENE_ASSOCIATION: YLR189C PROTEIN_ASSOCIATION: Ugt51 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
fast: false
name: R_UDP_glucoseergosterol_glucosyltransferase

395447
stoichiometry: 1.0
species: 283830
type: SpeciesReference

303288
value: -0.017521
type: LocalParameter

287191
kinetic law: 346295
product: 346283
reactant: 346271
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_hydroxy_2_oxoglutarate_mitochondrial_transport_via_diffusion
type: Reaction

284861
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Heme_A_C49H55FeN4O6
type: Species

292125
value: 0.0
type: LocalParameter

301462
value: 0.0
type: LocalParameter

283923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282873
name: M_Ceramide_2__Phytosphingosinen_C260__C44H89NO4
type: Species

288671
kinetic law: 376626
product: 376614
reactant: 376602
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Galacturonate_exchange
type: Reaction

285652
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M__R__Pantoate_C6H11O4
type: Species

421113
stoichiometry: 1.0
species: 284052
type: SpeciesReference

299442
value: 0.008175
type: LocalParameter

292816
value: 0.0
type: LocalParameter

289201
reversible: false
notes: GENE_ASSOCIATION: YLR011W PROTEIN_ASSOCIATION: Lot6 SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS:
type: Reaction
kinetic law: 389815
name: R_FMN_reductase
fast: false
reactant: 389755
reactant: 389779
product: 389803
product: 389791
reactant: 389767

301689
value: 0.0
type: LocalParameter

344142
stoichiometry: 1.0
species: 282993
type: SpeciesReference

288337
notes: GENE_ASSOCIATION: YCR036W PROTEIN_ASSOCIATION: Rbk1 SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 2.7.1.15
product: 371310
product: 371285
product: 371298
name: R_Deoxyribokinase
reactant: 371259
reactant: 371272
type: Reaction
kinetic law: 371322
fast: false
reversible: false

291173
value: 0.0
type: LocalParameter

390215
stoichiometry: 1.0
species: 284418
type: SpeciesReference

299339
value: -0.023956
type: LocalParameter

283920
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_2__Phytosphingosinen_C260__C44H89NO4
type: Species

358426
stoichiometry: 1.0
species: 284618
type: SpeciesReference

298079
value: 999999.0
type: LocalParameter

299444
value: 0.0
type: LocalParameter

301461
value: 0.0
type: LocalParameter

428106
stoichiometry: 1.0
species: 284808
type: SpeciesReference

289203
reactant: 389839
kinetic law: 389877
type: Reaction
name: R_dihydropteroate_synthase__mitochondrial
notes: GENE_ASSOCIATION: YNL256W PROTEIN_ASSOCIATION: Fol1-m SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 2.5.1.15
fast: false
reversible: false
product: 389864
reactant: 389827
product: 389852

375633
stoichiometry: 1.0
species: 286675
type: SpeciesReference

287194
kinetic law: 346331
product: 346319
reactant: 346307
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_hydroxy_2_oxoglutarate_peroxisomal_transport_via_diffusion
type: Reaction

289141
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:
reactant: 387163
product: 387248
reactant: 387151
reactant: 387187
product: 387199
name: R_fatty_acyl_ACP_synthase__n_C180ACP___mitochondrial
reactant: 387175
reversible: false
fast: false
kinetic law: 387260
product: 387211
product: 387223
product: 387236
type: Reaction

298078
value: 0.0
type: LocalParameter

369629
stoichiometry: 1.0
species: 284217
type: SpeciesReference

301535
value: 0.0
type: LocalParameter

288941
kinetic law: 379906
product: 379894
reactant: 379881
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Urea_exchange
type: Reaction

415863
stoichiometry: 1.0
species: 284085
type: SpeciesReference

384966
stoichiometry: 3.0
species: 285499
type: SpeciesReference

288334
notes: GENE_ASSOCIATION: YLR355C PROTEIN_ASSOCIATION: Ilv5-m SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 1.1.1.169
reversible: false
reactant: 371206
name: R_2_dehydropantoate_2_reductase__mitochondrial
reactant: 371180
type: Reaction
fast: false
product: 371220
product: 371233
kinetic law: 371246
reactant: 371193

428990
stoichiometry: 1.0
species: 284184
type: SpeciesReference

384228
stoichiometry: 8.0
species: 285418
type: SpeciesReference

429233
stoichiometry: 1.0
species: 284757
type: SpeciesReference

417908
stoichiometry: 1.0
species: 285751
type: SpeciesReference

368143
stoichiometry: 1.0
species: 284757
type: SpeciesReference

373727
stoichiometry: 0.02
species: 284831
type: SpeciesReference

303286
value: 0.0
type: LocalParameter

293823
value: 0.0
type: LocalParameter

399949
stoichiometry: 1.0
species: 284769
type: SpeciesReference

292814
value: 999999.0
type: LocalParameter

430951
stoichiometry: 1.0
species: 286231
type: SpeciesReference

299445
value: -999999.0
type: LocalParameter

292123
value: 0.016495
type: LocalParameter

291069
value: 0.0
type: LocalParameter

298077
value: 0.0
type: LocalParameter

369569
stoichiometry: 1.0
species: 282968
type: SpeciesReference

410603
stoichiometry: 1.0
species: 284787
type: SpeciesReference

390905
stoichiometry: 1.0
species: 284790
type: SpeciesReference

301534
value: 0.0
type: LocalParameter

294464
value: 0.0
type: LocalParameter

283590
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Adenine_C5H5N5
type: Species

411448
stoichiometry: 1.0
species: 285309
type: SpeciesReference

288448
fast: false
product: 373715
product: 373751
reversible: false
product: 373763
notes: GENE_ASSOCIATION: YLR020C PROTEIN_ASSOCIATION: Yeh2-e SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
type: Reaction
name: R_ergosterol_ester_hydrolase__yeast_specific__extracellular_
kinetic law: 373799
reactant: 373691
product: 373727
reactant: 373679
product: 373775
product: 373703
product: 373787
product: 373739

357342
stoichiometry: 1.0
species: 283764
type: SpeciesReference

443572
stoichiometry: 0.1647
species: 285841
type: SpeciesReference

293378
value: 0.0
type: LocalParameter

283719
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_AMP_C10H12N5O7P
type: Species

289223
product: 390432
reactant: 390384
fast: false
name: R_5_formethyltetrahydrofolate_cyclo_ligase__mitochondrial
reversible: false
reactant: 390396
product: 390408
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 6.3.3.2
kinetic law: 390444
product: 390420
type: Reaction

353224
stoichiometry: 1.0
species: 284624
type: SpeciesReference

298190
value: 999999.0
type: LocalParameter

352646
stoichiometry: 1.0
species: 284796
type: SpeciesReference

289590
kinetic law: 402292
reactant: 402231
reactant: 402243
reversible: false
product: 402280
type: Reaction
notes: GENE_ASSOCIATION: YJR139C PROTEIN_ASSOCIATION: Hom6 SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.1.1.3
reactant: 402256
name: R_homoserine_dehydrogenase__NADH___irreversible
fast: false
product: 402268

292103
value: 0.0
type: LocalParameter

407916
stoichiometry: 1.0
species: 286030
type: SpeciesReference

436627
stoichiometry: 1.0
species: 285754
type: SpeciesReference

284532
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_D_Galactose_C6H12O6
type: Species

293693
value: 999999.0
type: LocalParameter

420327
stoichiometry: 1.0
species: 285502
type: SpeciesReference

282990
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Deoxy_D_glucose_C6H12O5
type: Species

301476
value: 0.0
type: LocalParameter

362724
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298191
value: 0.0
type: LocalParameter

430187
stoichiometry: 1.0
species: 284787
type: SpeciesReference

288124
product: 366694
reversible: false
kinetic law: 366706
type: Reaction
notes: GENE_ASSOCIATION: YGL184C PROTEIN_ASSOCIATION: Str3-p SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.4.1.8
product: 366682
product: 366670
reactant: 366658
fast: false
reactant: 366646
name: R_cystathione_b_lyase__peroxisomal

290698
product: 438264
reversible: false
reactant: 438227
kinetic law: 438288
name: R_thiamine_phosphate_diphosphorylase
notes: GENE_ASSOCIATION: YPL214C PROTEIN_ASSOCIATION: Thi6 SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.5.1.3
product: 438276
reactant: 438252
fast: false
type: Reaction
reactant: 438240

302286
value: 999999.0
type: LocalParameter

434789
stoichiometry: 1.0
species: 286105
type: SpeciesReference

433588
stoichiometry: 1.0
species: 286069
type: SpeciesReference

378868
stoichiometry: 1.0
species: 285844
type: SpeciesReference

300900
value: 999999.0
type: LocalParameter

293814
value: -999999.0
type: LocalParameter

289221
reactant: 390311
reversible: false
fast: false
reactant: 390323
kinetic law: 390372
product: 390335
notes: GENE_ASSOCIATION: YER183C PROTEIN_ASSOCIATION: Fau1 SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 6.3.3.2
product: 390359
product: 390347
name: R_5_formethyltetrahydrofolate_cyclo_ligase
type: Reaction

436482
stoichiometry: 1.0
species: 286225
type: SpeciesReference

301479
value: 0.0
type: LocalParameter

293817
value: 999999.0
type: LocalParameter

419082
stoichiometry: 1.0
species: 285601
type: SpeciesReference

288127
fast: false
notes: GENE_ASSOCIATION: YNL247W PROTEIN_ASSOCIATION: Cyt1 SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.16
reactant: 366742
product: 366780
reactant: 366718
name: R_Cysteinyl_tRNA_synthetase
reactant: 366730
reversible: false
product: 366767
product: 366755
kinetic law: 366792
type: Reaction

429922
stoichiometry: 1.0
species: 283512
type: SpeciesReference

292105
value: 0.0
type: LocalParameter

370708
stoichiometry: 1.0
species: 284262
type: SpeciesReference

430747
stoichiometry: 1.0
species: 284790
type: SpeciesReference

443632
stoichiometry: 0.1854
species: 286030
type: SpeciesReference

302289
value: 0.087595
type: LocalParameter

293695
value: 0.0
type: LocalParameter

288881
kinetic law: 379181
product: 379169
reactant: 379157
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Serine_exchange
type: Reaction

379024
stoichiometry: 1.0
species: 286954
type: SpeciesReference

284421
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Fe2_Fe
type: Species

298193
value: 0.0
type: LocalParameter

288776
kinetic law: 377907
product: 377895
reactant: 377883
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Lysine_exchange
type: Reaction

419142
stoichiometry: 1.0
species: 285592
type: SpeciesReference

284535
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Galactose_C6H12O6
type: Species

351793
stoichiometry: 1.0
species: 284493
type: SpeciesReference

290696
type: Reaction
name: R_thiamine_phosphate_kinase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.7.4.16
product: 438203
reactant: 438179
kinetic law: 438215
product: 438191
reactant: 438167
reversible: true
fast: false

397791
stoichiometry: 1.0
species: 284711
type: SpeciesReference

302288
value: 0.0
type: LocalParameter

286192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Thiamine_diphosphate_C12H16N4O7P2S
type: Species

385317
stoichiometry: 2.0
species: 285436
type: SpeciesReference

397065
stoichiometry: 1.0
species: 284660
type: SpeciesReference

293819
value: 0.0
type: LocalParameter

349942
stoichiometry: 1.0
species: 284016
type: SpeciesReference

288779
kinetic law: 377943
product: 377931
reactant: 377919
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Malate_exchange
type: Reaction

432343
stoichiometry: 1.0
species: 285766
type: SpeciesReference

299460
value: 999999.0
type: LocalParameter

301328
value: 0.0
type: LocalParameter

284867
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_hexacosanoate__n_C260__C26H51O2
type: Species

372340
stoichiometry: 1.0
species: 284325
type: SpeciesReference

299675
value: 0.0
type: LocalParameter

301690
value: 999999.0
type: LocalParameter

356655
stoichiometry: 1.0
species: 284376
type: SpeciesReference

293697
value: 0.0
type: LocalParameter

443404
stoichiometry: 1.0E-6
species: 284720
type: SpeciesReference

292107
value: 0.0
type: LocalParameter

357113
stoichiometry: 1.0
species: 283761
type: SpeciesReference

406668
stoichiometry: 0.01
species: 285131
type: SpeciesReference

370900
stoichiometry: 1.0
species: 283836
type: SpeciesReference

411219
stoichiometry: 1.0
species: 284799
type: SpeciesReference

428845
stoichiometry: 1.0
species: 283584
type: SpeciesReference

289371
notes: GENE_ASSOCIATION: YMR250W PROTEIN_ASSOCIATION: Gad1 SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 4.1.1.15
reversible: false
product: 395230
reactant: 395206
reactant: 395194
name: R_Glutamate_Decarboxylase
product: 395218
kinetic law: 395242
type: Reaction
fast: false

299673
value: 999999.0
type: LocalParameter

297999
value: 0.0
type: LocalParameter

422104
stoichiometry: 1.0
species: 284796
type: SpeciesReference

414363
stoichiometry: 1.0
species: 284787
type: SpeciesReference

383963
stoichiometry: 7.0
species: 285418
type: SpeciesReference

350050
stoichiometry: 1.0
species: 283572
type: SpeciesReference

286198
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Thiamine_diphosphate_C12H16N4O7P2S
type: Species

302282
value: 0.0
type: LocalParameter

301691
value: 0.0
type: LocalParameter

405496
stoichiometry: 1.0
species: 283134
type: SpeciesReference

399809
stoichiometry: 1.0
species: 283992
type: SpeciesReference

292108
value: 0.0
type: LocalParameter

430103
stoichiometry: 1.0
species: 285943
type: SpeciesReference

300904
value: 0.0
type: LocalParameter

391521
stoichiometry: 1.0
species: 284669
type: SpeciesReference

299672
value: -999999.0
type: LocalParameter

292820
value: 0.0
type: LocalParameter

299568
value: 0.0
type: LocalParameter

286195
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thiamine_diphosphate_C12H16N4O7P2S
type: Species

374475
stoichiometry: 1.0
species: 286579
type: SpeciesReference

284538
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_D_Galacturonate_C6H9O7
type: Species

302285
value: -999999.0
type: LocalParameter

288352
kinetic law: 371602
product: 371590
reactant: 371578
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_dUMP_nuclear_transport
type: Reaction

300903
value: 0.0
type: LocalParameter

293699
value: -0.033063
type: LocalParameter

400555
stoichiometry: 1.0
species: 285240
type: SpeciesReference

379241
stoichiometry: 1.0
species: 286972
type: SpeciesReference

297840
value: 0.0
type: LocalParameter

442134
stoichiometry: 1.0
species: 284790
type: SpeciesReference

440589
stoichiometry: 1.0
species: 284648
type: SpeciesReference

414752
stoichiometry: 1.0
species: 285463
type: SpeciesReference

299671
value: 0.0
type: LocalParameter

422633
stoichiometry: 0.01
species: 285910
type: SpeciesReference

384637
stoichiometry: 8.0
species: 285418
type: SpeciesReference

418551
stoichiometry: 1.0
species: 285553
type: SpeciesReference

292821
value: -999999.0
type: LocalParameter

299567
value: 0.0
type: LocalParameter

283716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_AMP_C10H12N5O7P
type: Species

369775
stoichiometry: 1.0
species: 284220
type: SpeciesReference

301693
value: 0.0
type: LocalParameter

433274
stoichiometry: 1.0
species: 283149
type: SpeciesReference

302284
value: 0.0
type: LocalParameter

344203
stoichiometry: 1.0
species: 282990
type: SpeciesReference

373099
stoichiometry: 1.0
species: 284787
type: SpeciesReference

388200
stoichiometry: 3.0
species: 283992
type: SpeciesReference

290546
product: 433105
name: R_S_Formylglutathione_hydralase
reversible: true
product: 433117
reactant: 433069
type: Reaction
product: 433093
notes: GENE_ASSOCIATION: YJL068C PROTEIN_ASSOCIATION: Sfgh SUBSYSTEM: S_Methane_Metabolism PROTEIN_CLASS: 3.1.2.12
reactant: 433081
kinetic law: 433129
fast: false

368022
stoichiometry: 1.0
species: 284136
type: SpeciesReference

284427
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Fe2_Fe
type: Species

302174
value: 999999.0
type: LocalParameter

422213
stoichiometry: 1.0
species: 285730
type: SpeciesReference

299679
value: -999999.0
type: LocalParameter

366429
stoichiometry: 1.0
species: 283575
type: SpeciesReference

418443
stoichiometry: 1.0
species: 284787
type: SpeciesReference

301323
value: 0.0
type: LocalParameter

293928
value: -1.494988
type: LocalParameter

298198
value: 0.0
type: LocalParameter

356763
stoichiometry: 1.0
species: 283755
type: SpeciesReference

435730
stoichiometry: 1.0
species: 283641
type: SpeciesReference

299351
value: 0.0
type: LocalParameter

297843
value: -999999.0
type: LocalParameter

297996
value: 0.0
type: LocalParameter

288238
product: 369217
kinetic law: 369229
fast: false
notes: GENE_ASSOCIATION: ( YML070W or YFL053W ) PROTEIN_ASSOCIATION: ( Dak1 ) or ( Dak2 ) SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS: 2.7.1.29
reversible: false
reactant: 369169
product: 369193
reactant: 369181
name: R_dihydroxyacetone_kinase
product: 369205
type: Reaction

411109
stoichiometry: 1.0
species: 283839
type: SpeciesReference

299678
value: 0.0
type: LocalParameter

302173
value: -999999.0
type: LocalParameter

283710
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Adenosine_2__phosphate_C10H14N5O7P
type: Species

299565
value: 999999.0
type: LocalParameter

292710
value: 0.0
type: LocalParameter

418199
stoichiometry: 1.0
species: 285493
type: SpeciesReference

290690
reactant: 437971
type: Reaction
reactant: 437984
name: R_thiamine_diphosphate_kinase
notes: GENE_ASSOCIATION: YOR143C PROTEIN_ASSOCIATION: Thi80 SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 2.7.4.15
reversible: false
kinetic law: 438020
product: 437996
product: 438008
fast: false

299350
value: 0.0
type: LocalParameter

288887
kinetic law: 379254
product: 379241
reactant: 379229
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Sulfate_exchange
type: Reaction

432451
stoichiometry: 1.0
species: 285396
type: SpeciesReference

298199
value: 0.801635
type: LocalParameter

289375
reactant: 395374
notes: GENE_ASSOCIATION: ( YOR375C or YAL062W ) PROTEIN_ASSOCIATION: ( Gdh1 ) or ( Gdh3 ) SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 1.4.1.4
reactant: 395386
fast: false
kinetic law: 395435
reversible: false
reactant: 395350
product: 395410
reactant: 395362
product: 395398
type: Reaction
product: 395422
name: R_glutamate_dehydrogenase__NADP_

293228
value: 0.0
type: LocalParameter

440434
stoichiometry: 1.0
species: 286450
type: SpeciesReference

289598
fast: false
reactant: 402522
type: Reaction
kinetic law: 402558
reactant: 402510
name: R_histidinol_phosphate_transaminase
product: 402534
product: 402546
reversible: false
notes: GENE_ASSOCIATION: YIL116W PROTEIN_ASSOCIATION: His5 SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 2.6.1.9

297842
value: 0.0
type: LocalParameter

297995
value: 999999.0
type: LocalParameter

437597
stoichiometry: 3.0
species: 284757
type: SpeciesReference

289596
fast: false
name: R_homoserine_kinase
product: 402474
reversible: false
product: 402486
type: Reaction
notes: GENE_ASSOCIATION: YHR025W PROTEIN_ASSOCIATION: Thr1 SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.7.1.39
kinetic law: 402498
product: 402462
reactant: 402438
reactant: 402450

302176
value: 0.0
type: LocalParameter

290544
product: 433045
notes: GENE_ASSOCIATION: ( YFL055W or YCL025C or YDR508C or YKR039W or YPL265W ) PROTEIN_ASSOCIATION: ( Agp3 ) or ( Agp1 ) or ( Gnp1 ) or ( Gap1 ) or ( Dip5 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
name: R_L_serine_reversible_transport_via_proton_symport
product: 433033
fast: false
reactant: 433021
kinetic law: 433057
reversible: true
reactant: 433009
type: Reaction

288461
product: 374039
reversible: false
product: 374015
reactant: 374003
reactant: 373991
name: R_Ethanolamine_kinase
product: 374027
kinetic law: 374051
notes: GENE_ASSOCIATION: YDR147W PROTEIN_ASSOCIATION: Eki1 SUBSYSTEM: S_Phospholipid_Biosynthesis PROTEIN_CLASS: 2.7.1.82
fast: false
type: Reaction

374366
stoichiometry: 1.0
species: 286570
type: SpeciesReference

299564
value: 0.0
type: LocalParameter

295082
value: 0.0
type: LocalParameter

284978
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_isobutyl_alcohol_C4H10O
type: Species

283713
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_AMP_C10H12N5O7P
type: Species

433698
stoichiometry: 1.0
species: 285877
type: SpeciesReference

297845
value: 0.0
type: LocalParameter

299563
value: 0.0
type: LocalParameter

301326
value: 0.0
type: LocalParameter

415163
stoichiometry: 1.0
species: 284690
type: SpeciesReference

297998
value: 0.0
type: LocalParameter

383855
stoichiometry: 7.0
species: 284025
type: SpeciesReference

391183
stoichiometry: 1.0
species: 285186
type: SpeciesReference

435948
stoichiometry: 1.0
species: 286144
type: SpeciesReference

355508
stoichiometry: 1.0
species: 283683
type: SpeciesReference

299676
value: -0.085323
type: LocalParameter

417310
stoichiometry: 1.0
species: 286483
type: SpeciesReference

292712
value: 0.0
type: LocalParameter

295081
value: -0.214216
type: LocalParameter

436772
stoichiometry: 1.0
species: 286204
type: SpeciesReference

353804
stoichiometry: 1.0
species: 283071
type: SpeciesReference

301327
value: 0.0
type: LocalParameter

384528
stoichiometry: 8.0
species: 284025
type: SpeciesReference

289373
type: Reaction
notes: GENE_ASSOCIATION: YDL215C PROTEIN_ASSOCIATION: Gdh2 SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 1.4.1.2
reactant: 395266
product: 395326
product: 395290
kinetic law: 395338
reactant: 395254
reversible: false
product: 395314
product: 395302
reactant: 395278
fast: false
name: R_glutamate_dehydrogenase__NAD_

388358
stoichiometry: 6.0
species: 285421
type: SpeciesReference

297844
value: 999999.0
type: LocalParameter

288770
kinetic law: 377835
product: 377822
reactant: 377810
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_lanosterol_ester__yeast_specific_exchange
type: Reaction

437403
stoichiometry: 1.0
species: 283335
type: SpeciesReference

420436
stoichiometry: 1.0
species: 284757
type: SpeciesReference

293924
value: 999999.0
type: LocalParameter

290768
kinetic law: 440460
product: 440447
reactant: 440434
notes: GENE_ASSOCIATION: YPL244C PROTEIN_ASSOCIATION: Hut1-g SUBSYSTEM: S_Transport__Golgi_Apparatus PROTEIN_CLASS:
fast: false
reversible: false
name: R_UDPgalactose_transport__Golgi_apparatus_
type: Reaction

290542
product: 432972
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
name: R_serine_mitochondrial_transport_via_proton_symport
reactant: 432948
product: 432985
fast: false
reversible: true
type: Reaction
kinetic law: 432997
reactant: 432960

407807
stoichiometry: 0.01
species: 285670
type: SpeciesReference

289594
fast: false
reversible: true
type: Reaction
notes: GENE_ASSOCIATION: YNL277W PROTEIN_ASSOCIATION: Met2 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 2.3.1.31
reactant: 402376
product: 402413
kinetic law: 402426
reactant: 402389
name: R_homoserine_O_trans_acetylase
product: 402401

415016
stoichiometry: 1.0
species: 284790
type: SpeciesReference

409073
stoichiometry: 1.0
species: 285237
type: SpeciesReference

427646
stoichiometry: 1.0
species: 285421
type: SpeciesReference

297992
value: 0.0
type: LocalParameter

412272
stoichiometry: 0.01
species: 282893
type: SpeciesReference

439749
stoichiometry: 1.0
species: 283647
type: SpeciesReference

414860
stoichiometry: 1.0
species: 284787
type: SpeciesReference

299561
value: 0.0
type: LocalParameter

298194
value: -0.011879
type: LocalParameter

297847
value: 8.92488
type: LocalParameter

288884
kinetic law: 379217
product: 379205
reactant: 379193
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Sulfite_exchange
type: Reaction

415707
stoichiometry: 1.0
species: 284190
type: SpeciesReference

284424
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Fe2_Fe
type: Species

290694
reactant: 438106
reactant: 438093
product: 438118
product: 438143
product: 438131
reversible: false
fast: false
kinetic law: 438155
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Thiamine_Metabolism PROTEIN_CLASS: 3.5.99.2
name: R_thiaminase
type: Reaction

397621
stoichiometry: 1.0
species: 284787
type: SpeciesReference

293923
value: -999999.0
type: LocalParameter

297990
value: 0.0
type: LocalParameter

288232
kinetic law: 369109
product: 369097
product: 369084
reactant: 369071
notes: GENE_ASSOCIATION: YJR016C PROTEIN_ASSOCIATION: Ilv3-m SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 4.2.1.9
fast: false
reversible: false
name: R_dihydroxy_acid_dehydratase__2_3_dihydroxy_3_methylbutanoate___mitochondrial
type: Reaction

434898
stoichiometry: 1.0
species: 285751
type: SpeciesReference

430819
stoichiometry: 1.0
species: 285991
type: SpeciesReference

381091
stoichiometry: 1.0
species: 284834
type: SpeciesReference

283497
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetate_C2H3O2
type: Species

302177
value: 0.0
type: LocalParameter

297991
value: -0.001488
type: LocalParameter

400664
stoichiometry: 1.0
species: 284787
type: SpeciesReference

396810
stoichiometry: 1.0
species: 284787
type: SpeciesReference

294308
value: 0.0
type: LocalParameter

295088
value: 0.0
type: LocalParameter

299560
value: 0.0
type: LocalParameter

298195
value: 0.0
type: LocalParameter

378976
stoichiometry: 1.0
species: 285946
type: SpeciesReference

289379
type: Reaction
product: 395543
fast: false
name: R_glutaminase
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Glutamine_Metabolism PROTEIN_CLASS: 3.5.1.2
reactant: 395519
reactant: 395531
kinetic law: 395567
product: 395555
reversible: false

290540
type: Reaction
fast: false
product: 432900
reversible: false
name: R_Seryl_tRNA_synthetase
reactant: 432888
notes: GENE_ASSOCIATION: ( YHR011W or YDR023W ) PROTEIN_ASSOCIATION: ( Dia4 ) or ( Ses1 ) SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.11
product: 432912
reactant: 432863
reactant: 432876
product: 432924
kinetic law: 432936

290766
kinetic law: 440421
product: 440407
reactant: 440394
notes: GENE_ASSOCIATION: YBR019C PROTEIN_ASSOCIATION: Gal10 SUBSYSTEM: S_Galactose_metabolism PROTEIN_CLASS: 5.1.3.2
fast: false
reversible: true
name: R_UDPglucose_4_epimerase
type: Reaction

289592
product: 402340
notes: GENE_ASSOCIATION: YJR139C PROTEIN_ASSOCIATION: Hom6 SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.1.1.3
reactant: 402316
reactant: 402328
kinetic law: 402364
reactant: 402304
type: Reaction
reversible: false
product: 402352
name: R_homoserine_dehydrogenase__NADP___irreversible
fast: false

294305
value: 999999.0
type: LocalParameter

288773
kinetic law: 377871
product: 377859
reactant: 377847
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Leucine_exchange
type: Reaction

298196
value: 999999.0
type: LocalParameter

297849
value: -999999.0
type: LocalParameter

404348
stoichiometry: 1.0
species: 285050
type: SpeciesReference

301322
value: 999999.0
type: LocalParameter

293925
value: 0.0
type: LocalParameter

295085
value: 999999.0
type: LocalParameter

290692
reversible: false
reactant: 438032
type: Reaction
product: 438069
name: R_thymidylate_synthase
reactant: 438044
fast: false
kinetic law: 438081
notes: GENE_ASSOCIATION: YOR074C PROTEIN_ASSOCIATION: Cdc21 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.1.45
product: 438057

293690
value: 0.0
type: LocalParameter

372498
stoichiometry: 1.0
species: 284778
type: SpeciesReference

302179
value: 0.0
type: LocalParameter

419578
stoichiometry: 1.0
species: 283641
type: SpeciesReference

297993
value: 0.0
type: LocalParameter

357486
stoichiometry: 1.0
species: 283449
type: SpeciesReference

352706
stoichiometry: 1.0
species: 284016
type: SpeciesReference

288235
kinetic law: 369157
product: 369145
product: 369133
reactant: 369121
notes: GENE_ASSOCIATION: YJR016C PROTEIN_ASSOCIATION: Ilv3-m SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS:
fast: false
reversible: false
name: R_dihydroxy_acid_dehydratase__2_3_dihydroxy_3_methylpentanoate___mitochondrial
type: Reaction

297848
value: 0.0
type: LocalParameter

289377
fast: false
reversible: false
product: 395483
name: R_Glucokinase
product: 395495
kinetic law: 395507
notes: GENE_ASSOCIATION: YCL040W PROTEIN_ASSOCIATION: Glk1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.2
reactant: 395447
product: 395471
reactant: 395459
type: Reaction

297838
value: 999999.0
type: LocalParameter

289157
fast: false
product: 388224
reactant: 388152
reactant: 388176
product: 388236
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.86
product: 388200
product: 388212
name: R_fatty_acyl_CoA_synthase__n_C80CoA___lumped_reaction
product: 388248
reactant: 388164
reactant: 388188
reversible: false
kinetic law: 388260
type: Reaction

421404
stoichiometry: 1.0
species: 284418
type: SpeciesReference

428546
stoichiometry: 1.0
species: 284271
type: SpeciesReference

357991
stoichiometry: 1.0
species: 283797
type: SpeciesReference

413587
stoichiometry: 1.0
species: 285436
type: SpeciesReference

288455
kinetic law: 373943
product: 373931
reactant: 373919
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_ergosterol_endoplasmic_reticular_transport
type: Reaction

407201
stoichiometry: 1.0
species: 284790
type: SpeciesReference

293232
value: 0.0
type: LocalParameter

411328
stoichiometry: 1.0
species: 283839
type: SpeciesReference

285649
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M__R__Pantoate_C6H11O4
type: Species

291189
value: 0.0
type: LocalParameter

291076
value: 0.0
type: LocalParameter

443778
stoichiometry: 59.276
species: 283602
type: SpeciesReference

284981
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_isobutyl_alcohol_C4H10O
type: Species

301542
value: 0.0
type: LocalParameter

389089
stoichiometry: 1.0
species: 284787
type: SpeciesReference

299347
value: -999999.0
type: LocalParameter

287842
type: Reaction
reversible: true
kinetic law: 360427
name: R__R_R__butanediol_dehydrogenase
reactant: 360367
product: 360403
reactant: 360379
product: 360415
notes: GENE_ASSOCIATION: YAL060W PROTEIN_ASSOCIATION: Bdh1 SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.4
product: 360391
fast: false

364330
stoichiometry: 1.0
species: 285207
type: SpeciesReference

292717
value: 0.0
type: LocalParameter

297839
value: 0.0
type: LocalParameter

294315
value: 0.0
type: LocalParameter

293386
value: 999999.0
type: LocalParameter

390359
stoichiometry: 1.0
species: 285751
type: SpeciesReference

287290
fast: false
product: 348301
reactant: 348265
product: 348289
type: Reaction
product: 348277
reactant: 348241
kinetic law: 348325
reversible: true
name: R_acetyl_CoA_carboxylase__reversible_reaction
reactant: 348253
product: 348313
notes: GENE_ASSOCIATION: YNR016C PROTEIN_ASSOCIATION: Acc1 SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.4.1.2

368240
stoichiometry: 1.0
species: 285454
type: SpeciesReference

291077
value: 0.0
type: LocalParameter

288241
kinetic law: 369266
product: 369253
reactant: 369241
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: false
name: R_dihydroxyacetone_phosphate_transport__mitochondrial
type: Reaction

290764
reactant: 440344
reactant: 440332
product: 440369
kinetic law: 440381
notes: GENE_ASSOCIATION: YDL103C PROTEIN_ASSOCIATION: Qri1 SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 2.7.7.23
reversible: true
product: 440357
type: Reaction
reactant: 440320
name: R_UDP_N_acetylglucosamine_diphosphorylase
fast: false

283494
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Acetyl_ACP_C13H23N2O8PRS
type: Species

435513
stoichiometry: 1.0
species: 284757
type: SpeciesReference

287185
kinetic law: 346223
product: 346211
reactant: 346199
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_Aminobenzoate_mitochondrial_transport_via_diffusion
type: Reaction

289159
type: Reaction
name: R_fatty_acid_synthase__n_C80___lumped_reaction
product: 388371
reactant: 388272
reversible: false
product: 388358
product: 388332
kinetic law: 388384
reactant: 388308
product: 388345
reactant: 388296
product: 388320
notes: GENE_ASSOCIATION: ( YGR037C and YNR016C and ( YKL182W and YPL231W ) ) PROTEIN_ASSOCIATION: ( Acb1 and Acc1 and Fas ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reactant: 388284
fast: false

299348
value: 999999.0
type: LocalParameter

292002
value: 999999.0
type: LocalParameter

289155
kinetic law: 388140
fast: false
reactant: 388044
type: Reaction
product: 388116
product: 388128
reactant: 388068
reactant: 388032
reactant: 388056
name: R_fatty_acyl_ACP_synthase__n_C80ACP___mitochondrial__lumped_reaction
reversible: false
product: 388080
product: 388092
product: 388104
notes: GENE_ASSOCIATION: ( YKL192C and YER061C and YHR067W and YOR221C and YBR026C and YKL055C ) PROTEIN_ASSOCIATION: ( Acp1-m and Cem1-m and Htd2-m and Mct1-m and Mrf1-m and Oar1-m ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS:

294314
value: -0.085528
type: LocalParameter

293234
value: 0.0
type: LocalParameter

372061
stoichiometry: 1.0
species: 285949
type: SpeciesReference

284870
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_hexacosanoate__n_C260__C26H51O2
type: Species

291187
value: 999999.0
type: LocalParameter

345509
stoichiometry: 1.0
species: 284787
type: SpeciesReference

366646
stoichiometry: 1.0
species: 284067
type: SpeciesReference

299458
value: 0.0
type: LocalParameter

421259
stoichiometry: 1.0
species: 285679
type: SpeciesReference

410774
stoichiometry: 1.0
species: 285285
type: SpeciesReference

292719
value: 0.0
type: LocalParameter

301544
value: 0.0
type: LocalParameter

293388
value: 0.0
type: LocalParameter

357883
stoichiometry: 1.0
species: 286279
type: SpeciesReference

288458
kinetic law: 373979
product: 373967
reactant: 373955
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Endoplasmic_Reticular PROTEIN_CLASS:
fast: false
reversible: true
name: R_Ergosta_5_6_22_24__28__tetraen_3beta_ol_endoplamic_reticular_transport
type: Reaction

283491
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Acetyl_ACP_C13H23N2O8PRS
type: Species

374583
stoichiometry: 1.0
species: 286588
type: SpeciesReference

290762
notes: GENE_ASSOCIATION: ( YKL146W or YNL101W ) PROTEIN_ASSOCIATION: ( Avt3-v ) or ( Avt4-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
reactant: 440272
name: R_L_tyrosine_transport_out_via_proton_symport__vacuolar
reversible: false
kinetic law: 440308
product: 440296
product: 440284
reactant: 440260
type: Reaction
fast: false

292004
value: 0.0
type: LocalParameter

299346
value: 0.0
type: LocalParameter

287397
kinetic law: 350424
product: 350412
reactant: 350400
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_acetate_transport__mitochondrial
type: Reaction

301543
value: 0.0
type: LocalParameter

293922
value: 0.0
type: LocalParameter

299459
value: 0.0
type: LocalParameter

302180
value: 0.0
type: LocalParameter

291071
value: 999999.0
type: LocalParameter

352922
stoichiometry: 1.0
species: 284787
type: SpeciesReference

351125
stoichiometry: 1.0
species: 283608
type: SpeciesReference

345873
stoichiometry: 1.0
species: 283194
type: SpeciesReference

287845
kinetic law: 360463
product: 360451
reactant: 360439
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R__R_R__butanediol_transport
type: Reaction

293236
value: 0.0
type: LocalParameter

414641
stoichiometry: 1.0
species: 284247
type: SpeciesReference

288665
kinetic law: 376552
product: 376540
reactant: 376528
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_sn_Glycero_3_phospho_1_inositol_exchange
type: Reaction

298082
value: 0.0
type: LocalParameter

288551
kinetic law: 375175
product: 375163
reactant: 375151
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_S_Adenosyl_L_methionine_exchange
type: Reaction

285098
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_ITP_C10H11N4O14P3
type: Species

285532
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_octadecanoate__n_C180__C18H35O2
type: Species

302181
value: 999999.0
type: LocalParameter

295091
value: 0.0
type: LocalParameter

439640
stoichiometry: 1.0
species: 286171
type: SpeciesReference

405098
stoichiometry: 1.0
species: 283908
type: SpeciesReference

348217
stoichiometry: 1.0
species: 283512
type: SpeciesReference

400447
stoichiometry: 1.0
species: 284787
type: SpeciesReference

293797
value: 999999.0
type: LocalParameter

293380
value: 6.33E-4
type: LocalParameter

291072
value: 0.0
type: LocalParameter

298081
value: 0.0
type: LocalParameter

293382
value: 0.0
type: LocalParameter

299343
value: 0.0
type: LocalParameter

293237
value: 0.0
type: LocalParameter

294311
value: 0.0
type: LocalParameter

283305
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_4_Hydroxybenzoate_C7H5O3
type: Species

380813
stoichiometry: 1.0
species: 286165
type: SpeciesReference

290760
reactant: 440212
reactant: 440200
reversible: false
kinetic law: 440248
name: R_L_tyrosine_transport_in_via_proton_antiport__vacuolar_
fast: false
notes: GENE_ASSOCIATION: ( YBR293W or YJR001W ) PROTEIN_ASSOCIATION: ( Vba2-v ) or ( Avt1-v ) SUBSYSTEM: S_Transport__Vacuolar PROTEIN_CLASS:
product: 440224
type: Reaction
product: 440236

299344
value: 0.0
type: LocalParameter

292713
value: 0.0
type: LocalParameter

375850
stoichiometry: 1.0
species: 286693
type: SpeciesReference

285646
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_Pantetheine_4__phosphate_C11H21N2O7PS
type: Species

284984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Isocitrate_C6H5O7
type: Species

291073
value: 0.0
type: LocalParameter

380740
stoichiometry: 1.0
species: 286162
type: SpeciesReference

393851
stoichiometry: 1.0
species: 284757
type: SpeciesReference

391749
stoichiometry: 1.0
species: 285421
type: SpeciesReference

289588
reactant: 402158
product: 402207
product: 402182
type: Reaction
product: 402194
name: R_L_hydroxyproline_dehydrogenase__NADP___mitochondrial
reactant: 402170
fast: false
notes: GENE_ASSOCIATION: YHR037W PROTEIN_ASSOCIATION: Put2-m SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12
kinetic law: 402219
reversible: false

293383
value: 0.0
type: LocalParameter

369849
stoichiometry: 1.0
species: 284757
type: SpeciesReference

298084
value: 0.0
type: LocalParameter

288554
kinetic law: 375211
product: 375199
reactant: 375187
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Arabinose_exchange
type: Reaction

295199
value: 0.0
type: LocalParameter

362023
stoichiometry: 1.0
species: 283887
type: SpeciesReference

299340
value: -999999.0
type: LocalParameter

302183
value: 0.0
type: LocalParameter

403004
stoichiometry: 1.0
species: 284001
type: SpeciesReference

284987
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Isocitrate_C6H5O7
type: Species

287188
kinetic law: 346259
product: 346247
reactant: 346235
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_Aminobenzoate_mitochondrial_transport_via_diffusion
type: Reaction

293799
value: 0.0
type: LocalParameter

283302
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_4_Hydroxybenzoate_C7H5O3
type: Species

356208
stoichiometry: 1.0
species: 283584
type: SpeciesReference

288452
kinetic law: 373907
product: 373895
reactant: 373883
notes: GENE_ASSOCIATION: ( YIL013C or YOR011W ) PROTEIN_ASSOCIATION: ( Pdr11 ) or ( Aus1 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_ergosterol_reversible_transport
type: Reaction

363278
stoichiometry: 1.0
species: 285436
type: SpeciesReference

443127
stoichiometry: 1.1348
species: 282896
type: SpeciesReference

291070
value: 0.0
type: LocalParameter

288938
kinetic law: 379869
product: 379856
reactant: 379844
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Uracil_exchange
type: Reaction

352850
stoichiometry: 1.0
species: 283650
type: SpeciesReference

357053
stoichiometry: 1.0
species: 283713
type: SpeciesReference

299341
value: 999999.0
type: LocalParameter

293239
value: 999999.0
type: LocalParameter

288668
kinetic law: 376590
product: 376578
reactant: 376565
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_D_Galactose_exchange
type: Reaction

292000
value: 0.0
type: LocalParameter

285535
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_octadecanoate__n_C180__C18H35O2
type: Species

292715
value: 999999.0
type: LocalParameter

390143
stoichiometry: 1.0
species: 284580
type: SpeciesReference

350196
stoichiometry: 1.0
species: 284016
type: SpeciesReference

302184
value: 0.0
type: LocalParameter

365841
stoichiometry: 1.0
species: 284796
type: SpeciesReference

400107
stoichiometry: 1.0
species: 284787
type: SpeciesReference

290548
fast: false
reactant: 433153
product: 433189
notes: GENE_ASSOCIATION: YBR213W PROTEIN_ASSOCIATION: Met8 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS:
product: 433177
product: 433165
name: R_sirohydrochlorin_dehydrogenase
reactant: 433141
reversible: false
type: Reaction
kinetic law: 433201

414968
stoichiometry: 1.0
species: 285472
type: SpeciesReference

300908
value: -999999.0
type: LocalParameter

375742
stoichiometry: 1.0
species: 286684
type: SpeciesReference

284529
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_alpha_D_Galactose_1_phosphate_C6H11O9P
type: Species

282987
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_2_Dehydro_3_deoxy_D_arabino_heptonate_7_phosphate_C7H10O10P
type: Species

289219
kinetic law: 390299
name: R_D_fructose_transport_in_via_proton_symport
reactant: 390251
product: 390275
fast: false
notes: GENE_ASSOCIATION: ( YHR094C or YFL011W or YOL156W or YEL069C or YDL245C or YJR158W or YNR072W or YMR011W or YDR345C or YHR092C or YHR096C or YDR343C or YDR342C or YJL214W or YJL219W ) PROTEIN_ASSOCIATION: ( Hxt1 ) or ( Hxt10 ) or ( Hxt11 ) or ( Hxt13 ) or ( Hxt15 ) or ( Hxt16 ) or ( Hxt17 ) or ( Hxt2 ) or ( Hxt3 ) or ( Hxt4 ) or ( Hxt5 ) or ( Hxt6 ) or ( Hxt7 ) or ( Hxt8 ) or ( Hxt9 ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
reactant: 390263
product: 390287
type: Reaction
reversible: false

292823
value: 999999.0
type: LocalParameter

301695
value: 0.0
type: LocalParameter

284876
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

400976
stoichiometry: 1.0
species: 284757
type: SpeciesReference

299451
value: 0.0
type: LocalParameter

298086
value: 999999.0
type: LocalParameter

346488
stoichiometry: 1.0
species: 284016
type: SpeciesReference

363676
stoichiometry: 1.0
species: 283890
type: SpeciesReference

366586
stoichiometry: 1.0
species: 284757
type: SpeciesReference

291180
value: 0.0
type: LocalParameter

348843
stoichiometry: 1.0
species: 283497
type: SpeciesReference

384096
stoichiometry: 7.0
species: 285418
type: SpeciesReference

300909
value: 999999.0
type: LocalParameter

404240
stoichiometry: 1.0
species: 285035
type: SpeciesReference

356316
stoichiometry: 1.0
species: 285826
type: SpeciesReference

293689
value: -0.033063
type: LocalParameter

291182
value: 0.0
type: LocalParameter

387803
stoichiometry: 3.0
species: 285219
type: SpeciesReference

302291
value: 0.0
type: LocalParameter

301694
value: -0.011879
type: LocalParameter

348109
stoichiometry: 1.0
species: 286399
type: SpeciesReference

299452
value: -999999.0
type: LocalParameter

295198
value: -0.015839
type: LocalParameter

288557
kinetic law: 375247
product: 375235
reactant: 375223
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Arabinose_exchange
type: Reaction

287299
kinetic law: 348494
product: 348482
reactant: 348470
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: false
name: R_acetic_ester_transport__extracellular_
type: Reaction

298085
value: -999999.0
type: LocalParameter

288932
kinetic law: 379796
product: 379784
reactant: 379772
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_tetradecanoate__n_C140__exchange
type: Reaction

363978
stoichiometry: 1.0
species: 283239
type: SpeciesReference

414533
stoichiometry: 1.0
species: 284766
type: SpeciesReference

345981
stoichiometry: 1.0
species: 283200
type: SpeciesReference

383152
stoichiometry: 1.0
species: 285556
type: SpeciesReference

288343
product: 371444
product: 371456
fast: false
reactant: 371432
kinetic law: 371469
notes: GENE_ASSOCIATION: YOL066C PROTEIN_ASSOCIATION: Rib2 SUBSYSTEM: S_Riboflavin_Metabolism PROTEIN_CLASS:
reversible: false
reactant: 371407
type: Reaction
name: R_2_5_diamino_6_ribitylamino_4_3H__pyrimidinone_5__phosphate_deaminase
reactant: 371419

294470
value: 0.0
type: LocalParameter

285538
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_octadecenoate__n_C181__C18H33O2
type: Species

289696
kinetic law: 405424
product: 405412
reactant: 405400
notes: GENE_ASSOCIATION: YPL117C PROTEIN_ASSOCIATION: Idi1.1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 5.3.3.2
fast: false
reversible: true
name: R_isopentenyl_diphosphate_D_isomerase
type: Reaction

421838
stoichiometry: 1.0
species: 283602
type: SpeciesReference

301471
value: 0.0
type: LocalParameter

285643
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Pantetheine_4__phosphate_C11H21N2O7PS
type: Species

292110
value: 999999.0
type: LocalParameter

292825
value: 0.0
type: LocalParameter

302292
value: -999999.0
type: LocalParameter

403113
stoichiometry: 1.0
species: 284987
type: SpeciesReference

288662
kinetic law: 376516
product: 376504
reactant: 376492
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_sn_Glycero_3_phosphocholine_exchange
type: Reaction

289217
product: 390215
fast: false
reactant: 390179
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Fructose_and_Mannose_Metabolism PROTEIN_CLASS: 2.7.1.56
reactant: 390191
kinetic law: 390239
name: R_fructose_1_phosphate_kinase
product: 390203
reversible: false
product: 390227
type: Reaction

283938
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Cys_Gly_C5H10N2O3S
type: Species

301698
value: 999999.0
type: LocalParameter

286189
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Thiamin_monophosphate_C12H16N4O4PS
type: Species

294471
value: 0.0
type: LocalParameter

385461
stoichiometry: 1.0
species: 283992
type: SpeciesReference

427863
stoichiometry: 1.0
species: 285904
type: SpeciesReference

288935
kinetic law: 379832
product: 379820
reactant: 379808
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Tyrosine_exchange
type: Reaction

436324
stoichiometry: 1.0
species: 286252
type: SpeciesReference

282984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_2_Dehydro_3_deoxy_D_arabino_heptonate_7_phosphate_C7H10O10P
type: Species

288130
product: 366840
type: Reaction
reactant: 366816
kinetic law: 366852
name: R_cystathionine_beta_synthase
reactant: 366804
reversible: false
fast: false
notes: GENE_ASSOCIATION: YGR155W PROTEIN_ASSOCIATION: Cys4 SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 4.2.1.22
product: 366828

363386
stoichiometry: 1.0
species: 285487
type: SpeciesReference

300907
value: 0.0
type: LocalParameter

443235
stoichiometry: 0.0447
species: 283983
type: SpeciesReference

295195
value: 0.0
type: LocalParameter

302293
value: 999999.0
type: LocalParameter

301470
value: 0.016495
type: LocalParameter

287296
kinetic law: 348458
product: 348446
reactant: 348433
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Nuclear PROTEIN_CLASS:
fast: false
reversible: true
name: R_acetyl_CoA_transport__nuclear
type: Reaction

400216
stoichiometry: 1.0
species: 284837
type: SpeciesReference

365732
stoichiometry: 1.0
species: 284790
type: SpeciesReference

289004
reactant: 380873
reactant: 380885
product: 380909
type: Reaction
fast: false
kinetic law: 380933
name: R_fatty_acyl_ACP_hydrolase
reversible: true
product: 380921
notes: GENE_ASSOCIATION: ( YKL182W and YPL231W ) PROTEIN_ASSOCIATION: Fas SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 3.1.2.14
product: 380897

298087
value: 0.0
type: LocalParameter

289698
kinetic law: 405460
product: 405448
reactant: 405436
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_Isopentenyl_diphosphate_transport__mitochondrial
type: Reaction

287848
kinetic law: 360525
reactant: 360489
type: Reaction
product: 360513
notes: GENE_ASSOCIATION: YGR065C PROTEIN_ASSOCIATION: Vht1 SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
name: R_Biotin_uptake
reactant: 360476
product: 360501
reversible: false

407395
stoichiometry: 1.0
species: 285369
type: SpeciesReference

426497
stoichiometry: 1.0
species: 285796
type: SpeciesReference

358438
stoichiometry: 1.0
species: 283815
type: SpeciesReference

295192
value: 0.0
type: LocalParameter

283932
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_3__Phytosphingosinen_C240OH__C42H85NO5
type: Species

287182
kinetic law: 346187
product: 346175
reactant: 346163
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_4_aminobutanoate_mitochondrial_transport_via_diffusion
type: Reaction

289215
product: 390155
reversible: false
product: 390143
reactant: 390119
reactant: 390131
name: R_farnesyltranstransferase
notes: GENE_ASSOCIATION: YPL069C PROTEIN_ASSOCIATION: Bts1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS: 2.5.1.29
type: Reaction
kinetic law: 390167
fast: false

292112
value: 0.0
type: LocalParameter

299456
value: 0.0
type: LocalParameter

298398
value: 999999.0
type: LocalParameter

390203
stoichiometry: 1.0
species: 283602
type: SpeciesReference

291185
value: -999999.0
type: LocalParameter

303299
value: 0.0
type: LocalParameter

294477
value: 0.0
type: LocalParameter

384978
stoichiometry: 1.0
species: 285520
type: SpeciesReference

298397
value: -999999.0
type: LocalParameter

288346
fast: false
type: Reaction
product: 371517
kinetic law: 371530
product: 371505
notes: GENE_ASSOCIATION: YJR057W PROTEIN_ASSOCIATION: Cdc8 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.9
reactant: 371481
name: R_dTMP_kinase
reversible: true
reactant: 371493

415851
stoichiometry: 1.0
species: 283830
type: SpeciesReference

289153
type: Reaction
reactant: 387912
product: 387972
product: 388008
name: R_fatty_acid_synthase__n_C260_
product: 387996
product: 387960
reversible: false
reactant: 387936
fast: false
notes: GENE_ASSOCIATION: ( YCR034W and YLR372W and YDL015C ) PROTEIN_ASSOCIATION: ( Fen1 and Sur4 and Tsc13 ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
reactant: 387924
product: 387984
kinetic law: 388020
reactant: 387948

369617
stoichiometry: 1.0
species: 284214
type: SpeciesReference

408181
stoichiometry: 1.0
species: 285174
type: SpeciesReference

292827
value: 0.0
type: LocalParameter

301547
value: 999999.0
type: LocalParameter

396531
stoichiometry: 1.0
species: 284675
type: SpeciesReference

414206
stoichiometry: 1.0
species: 283602
type: SpeciesReference

301472
value: -999999.0
type: LocalParameter

384216
stoichiometry: 8.0
species: 284754
type: SpeciesReference

293811
value: 0.0
type: LocalParameter

368131
stoichiometry: 1.0
species: 284787
type: SpeciesReference

373739
stoichiometry: 0.655
species: 284840
type: SpeciesReference

443560
stoichiometry: 1.0E-6
species: 285733
type: SpeciesReference

411436
stoichiometry: 1.0
species: 284757
type: SpeciesReference

361079
stoichiometry: 1.0
species: 285409
type: SpeciesReference

298396
value: 0.0
type: LocalParameter

298089
value: 0.221001
type: LocalParameter

425664
stoichiometry: 1.0
species: 285396
type: SpeciesReference

301699
value: 0.0
type: LocalParameter

384360
stoichiometry: 8.0
species: 285418
type: SpeciesReference

364221
stoichiometry: 1.0
species: 284790
type: SpeciesReference

369557
stoichiometry: 1.0
species: 284217
type: SpeciesReference

289001
kinetic law: 380861
product: 380849
reactant: 380837
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: false
name: R_fatty_acid_peroxisomal_transport
type: Reaction

435621
stoichiometry: 0.24
species: 285538
type: SpeciesReference

287293
product: 348373
notes: GENE_ASSOCIATION: YMR207C PROTEIN_ASSOCIATION: Hfa1-m SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.4.1.2
product: 348409
fast: false
name: R_Acetyl_Coa_carboxylase__mitochondrial
kinetic law: 348421
reactant: 348349
reversible: true
reactant: 348361
type: Reaction
reactant: 348337
product: 348385
product: 348397

289213
fast: false
reversible: false
type: Reaction
reactant: 390059
product: 390095
name: R_fumarate_reductase
reactant: 390071
notes: GENE_ASSOCIATION: YJR051W PROTEIN_ASSOCIATION: Osm1-m SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.3.99.1
kinetic law: 390107
product: 390083

282981
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_1__2_Carboxyphenylamino__1_deoxy_D_ribulose_5_phosphate_C12H13NO9P
type: Species

301475
value: 999999.0
type: LocalParameter

373883
stoichiometry: 1.0
species: 284355
type: SpeciesReference

288133
kinetic law: 366888
product: 366876
reactant: 366864
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Peroxisomal PROTEIN_CLASS:
fast: false
reversible: true
name: R_cystathione_peroxisomal_transport
type: Reaction

400336
stoichiometry: 1.0
species: 284766
type: SpeciesReference

292114
value: 0.0
type: LocalParameter

291078
value: 999999.0
type: LocalParameter

293230
value: 999999.0
type: LocalParameter

289151
product: 387852
product: 387888
reactant: 387828
type: Reaction
product: 387840
reversible: false
kinetic law: 387900
product: 387876
reactant: 387803
notes: GENE_ASSOCIATION: ( YCR034W and YLR372W and YDL015C ) PROTEIN_ASSOCIATION: ( Fen1 and Sur4 and Tsc13 ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 2.3.1.85
name: R_fatty_acid_synthase__n_C240___lumped_reaction
product: 387864
fast: false
reactant: 387791
reactant: 387815

299453
value: 999999.0
type: LocalParameter

396969
stoichiometry: 1.0
species: 284687
type: SpeciesReference

359941
stoichiometry: 2.0
species: 284796
type: SpeciesReference

292829
value: 0.0
type: LocalParameter

299455
value: 0.0
type: LocalParameter

283935
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Ceramide_3__Phytosphingosinen_C260OH__C44H89NO5
type: Species

285640
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_Pantetheine_4__phosphate_C11H21N2O7PS
type: Species

293813
value: -0.08335
type: LocalParameter

291184
value: -0.058801
type: LocalParameter

394070
stoichiometry: 1.0
species: 284766
type: SpeciesReference

298399
value: 0.0
type: LocalParameter

291079
value: 0.0
type: LocalParameter

284873
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
name: M_hexacosanoate__n_C260__C26H51O2
type: Species

294474
value: 999999.0
type: LocalParameter

288349
kinetic law: 371566
product: 371554
reactant: 371542
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS:
fast: false
reversible: true
name: R_dTTP_reversible_uniport
type: Reaction

413697
stoichiometry: 1.0
species: 285276
type: SpeciesReference

374692
stoichiometry: 1.0
species: 286597
type: SpeciesReference

301548
value: 0.0
type: LocalParameter

287497
type: Reaction
product: 352550
notes: GENE_ASSOCIATION: ( YLR028C or YMR120C ) PROTEIN_ASSOCIATION: ( Ade16 ) or ( Ade17 ) SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.2.3
product: 352538
reversible: true
reactant: 352526
reactant: 352514
name: R_phosphoribosylaminoimidazolecarboxamide_formyltransferase
fast: false
kinetic law: 352562

364172
stoichiometry: 1.0
species: 284787
type: SpeciesReference

290308
reactant: 425400
kinetic law: 425448
product: 425424
reversible: false
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pantothenate_and_CoA_Biosynthesis PROTEIN_CLASS: 4.1.1.36
name: R_phosphopantothenoylcysteine_decarboxylase
fast: false
product: 425436
reactant: 425412
type: Reaction

284019
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282882
name: M_Coenzyme_A_C21H32N7O16P3S
type: Species

378880
stoichiometry: 1.0
species: 286942
type: SpeciesReference

440998
stoichiometry: 1.0
species: 284031
type: SpeciesReference

363845
stoichiometry: 1.0
species: 284787
type: SpeciesReference

441567
stoichiometry: 1.0
species: 284790
type: SpeciesReference

288424
kinetic law: 372931
product: 372919
reactant: 372907
reactant: 372895
notes: GENE_ASSOCIATION: YJR153W PROTEIN_ASSOCIATION: Pgu1-e SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS:
fast: false
reversible: false
name: R_Endopolygalacturonase__extracellular_
type: Reaction

293289
value: 0.0
type: LocalParameter

373703
stoichiometry: 0.01
species: 284355
type: SpeciesReference

293062
value: 0.0
type: LocalParameter

404649
stoichiometry: 1.0
species: 285309
type: SpeciesReference

302421
value: 0.0
type: LocalParameter

290861
value: 0.0
type: LocalParameter

303169
value: 999999.0
type: LocalParameter

298268
value: 999999.0
type: LocalParameter

303016
value: 0.0
type: LocalParameter

372219
stoichiometry: 1.0
species: 285107
type: SpeciesReference

298115
value: 0.0
type: LocalParameter

381439
stoichiometry: 1.0
species: 285523
type: SpeciesReference

301511
value: 999999.0
type: LocalParameter

287542
name: R_alcohol_dehydrogenase__glycerol__NADP_
reactant: 353465
fast: false
reversible: false
reactant: 353453
type: Reaction
product: 353489
reactant: 353441
product: 353477
kinetic law: 353501
notes: GENE_ASSOCIATION: ( YHR104W or YDR368W ) PROTEIN_ASSOCIATION: ( Gre3 ) or ( Ypr1 ) SUBSYSTEM: S_Glycerolipid_Metabolism PROTEIN_CLASS:

289165
kinetic law: 388534
product: 388522
product: 388510
reactant: 388497
notes: GENE_ASSOCIATION: YKL060C PROTEIN_ASSOCIATION: Fba1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 4.1.2.13
fast: false
reversible: true
name: R_Sedoheptulose_1_7_bisphosphate_D_glyceraldehyde_3_phosphate_lyase
type: Reaction

294340
value: 0.0
type: LocalParameter

286159
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
type: Species

357294
stoichiometry: 1.0
species: 284787
type: SpeciesReference

298839
value: 0.0
type: LocalParameter

296671
value: 0.0
type: LocalParameter

294441
value: -0.001036
type: LocalParameter

367526
stoichiometry: 1.0
species: 283890
type: SpeciesReference

296670
value: 999999.0
type: LocalParameter

439882
stoichiometry: 1.0
species: 283713
type: SpeciesReference

294857
value: 0.0
type: LocalParameter

429329
stoichiometry: 1.0
species: 285931
type: SpeciesReference

291522
value: 0.0
type: LocalParameter

298269
value: 0.0
type: LocalParameter

303017
value: 0.0
type: LocalParameter

300240
value: 0.0
type: LocalParameter

364233
stoichiometry: 1.0
species: 283962
type: SpeciesReference

434438
stoichiometry: 1.0
species: 284772
type: SpeciesReference

406150
stoichiometry: 1.0
species: 285487
type: SpeciesReference

298116
value: 0.0
type: LocalParameter

303019
value: -0.044942
type: LocalParameter

301512
value: 0.0
type: LocalParameter

287767
notes: GENE_ASSOCIATION: YKL106W PROTEIN_ASSOCIATION: Aat1-m SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 2.6.1.1
reactant: 358583
type: Reaction
name: R_aspartate_transaminase
reversible: true
product: 358607
fast: false
kinetic law: 358631
reactant: 358595
product: 358619

439290
stoichiometry: 1.0
species: 286381
type: SpeciesReference

286156
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

293065
value: 0.0
type: LocalParameter

302424
value: -0.011879
type: LocalParameter

374680
stoichiometry: 1.0
species: 283365
type: SpeciesReference

428010
stoichiometry: 1.0
species: 284778
type: SpeciesReference

284885
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
name: M_all_trans_Hexaprenyl_diphosphate_C30H49O7P2
type: Species

400349
stoichiometry: 1.0
species: 285733
type: SpeciesReference

294854
value: 0.0
type: LocalParameter

287494
kinetic law: 352502
fast: false
reactant: 352454
name: R_O_acetylhomoserine__thiol__lyase
reversible: false
reactant: 352442
product: 352466
product: 352478
type: Reaction
notes: GENE_ASSOCIATION: YLR303W PROTEIN_ASSOCIATION: Met17 SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.2.99.8
product: 352490

298117
value: 0.0
type: LocalParameter

290306
reversible: false
fast: false
product: 425364
type: Reaction
reactant: 425340
name: R_porphobilinogen_synthase
product: 425376
kinetic law: 425388
product: 425352
notes: GENE_ASSOCIATION: YGL040C PROTEIN_ASSOCIATION: Hem2 SUBSYSTEM: S_Porphyrin_and_Chlorophyll_Metabolism PROTEIN_CLASS: 4.2.1.24

409531
stoichiometry: 1.0
species: 284787
type: SpeciesReference

358221
stoichiometry: 1.0
species: 284805
type: SpeciesReference

385594
stoichiometry: 1.0
species: 284001
type: SpeciesReference

298720
value: 0.0
type: LocalParameter

294766
value: 0.161493
type: LocalParameter

289738
reactant: 406983
type: Reaction
kinetic law: 407019
fast: false
notes: GENE_ASSOCIATION: YHR208W PROTEIN_ASSOCIATION: Bat1-m SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 2.6.1.6
name: R_leucine_transaminase__mitochondrial
reactant: 406971
product: 406995
product: 407007
reversible: true

289163
kinetic law: 388485
product: 388473
product: 388461
reactant: 388449
notes: GENE_ASSOCIATION: YKL060C PROTEIN_ASSOCIATION: Fba1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 4.1.2.13
fast: false
reversible: true
name: R_D_Fructose_1_phosphate_D_glyceraldehyde_3_phosphate_lyase
type: Reaction

357690
stoichiometry: 1.0
species: 284760
type: SpeciesReference

384843
stoichiometry: 1.0
species: 286399
type: SpeciesReference

293064
value: 0.0
type: LocalParameter

294552
value: 999999.0
type: LocalParameter

344859
stoichiometry: 1.0
species: 283071
type: SpeciesReference

302422
value: 0.0
type: LocalParameter

298118
value: 999999.0
type: LocalParameter

291520
value: 0.0038
type: LocalParameter

411981
stoichiometry: 1.0
species: 285234
type: SpeciesReference

289059
reactant: 382522
fast: false
notes: GENE_ASSOCIATION: YER015W PROTEIN_ASSOCIATION: Faa2-p SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.2.1.3
reactant: 382509
reversible: true
product: 382572
reactant: 382535
product: 382560
product: 382547
name: R_fatty_acid__CoA_ligase__tetradecenoate___peroxisomal
kinetic law: 382584
type: Reaction

302426
value: 999999.0
type: LocalParameter

293285
value: 999999.0
type: LocalParameter

349990
stoichiometry: 1.0
species: 285661
type: SpeciesReference

295299
value: 0.0
type: LocalParameter

288920
kinetic law: 379652
product: 379640
reactant: 379628
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Thymine_exchange
type: Reaction

382572
stoichiometry: 1.0
species: 286165
type: SpeciesReference

298263
value: 0.0
type: LocalParameter

303165
value: -3.700069
type: LocalParameter

286153
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282885
type: Species

291525
value: 999999.0
type: LocalParameter

356304
stoichiometry: 1.0
species: 285796
type: SpeciesReference

288427
reactant: 372979
reactant: 372967
reactant: 373015
reactant: 373003
notes: GENE_ASSOCIATION: YCR048W PROTEIN_ASSOCIATION: Are1 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
kinetic law: 373051
reactant: 372991
reactant: 372955
fast: false
reversible: false
product: 373039
product: 373027
name: R_Acyl_CoAepisterol_acyltransferase__yeast_specific
type: Reaction
reactant: 372943

302425
value: 0.0
type: LocalParameter

284016
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_Coenzyme_A_C21H32N7O16P3S
type: Species

298835
value: 0.0
type: LocalParameter

393187
stoichiometry: 1.0
species: 284663
type: SpeciesReference

298722
value: -0.037419
type: LocalParameter

400940
stoichiometry: 1.0
species: 284897
type: SpeciesReference

429850
stoichiometry: 1.0
species: 284624
type: SpeciesReference

289161
kinetic law: 388436
product: 388423
product: 388410
reactant: 388397
notes: GENE_ASSOCIATION: YKL060C PROTEIN_ASSOCIATION: Fba1 SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 4.1.2.13
fast: false
reversible: true
name: R_fructose_bisphosphate_aldolase
type: Reaction

294344
value: 999999.0
type: LocalParameter

392221
stoichiometry: 1.0
species: 285053
type: SpeciesReference

294558
value: 0.0
type: LocalParameter

301515
value: 1.9E-5
type: LocalParameter

287349
product: 349494
kinetic law: 349518
reactant: 349470
notes: GENE_ASSOCIATION: YGL205W PROTEIN_ASSOCIATION: Pox1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 1.3.3.6
name: R_acyl_CoA_oxidase__hexacanoyl_CoA___peroxisomal
reversible: false
type: Reaction
reactant: 349482
product: 349506
fast: false

298264
value: 0.0
type: LocalParameter

303166
value: 0.0
type: LocalParameter

284888
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282879
name: M_all_trans_Hexaprenyl_diphosphate_C30H49O7P2
type: Species

373607
stoichiometry: 0.655
species: 284837
type: SpeciesReference

375199
stoichiometry: 1.0
species: 286639
type: SpeciesReference

375778
stoichiometry: 1.0
species: 286687
type: SpeciesReference

293287
value: 0.0
type: LocalParameter

353525
stoichiometry: 1.0
species: 284787
type: SpeciesReference

394563
stoichiometry: 1.0
species: 284618
type: SpeciesReference

298836
value: 0.0
type: LocalParameter

302428
value: 0.0
type: LocalParameter

382078
stoichiometry: 1.0
species: 283845
type: SpeciesReference

294555
value: 0.0
type: LocalParameter

294341
value: -999999.0
type: LocalParameter

426461
stoichiometry: 1.0
species: 284757
type: SpeciesReference

301516
value: 0.0
type: LocalParameter

287545
reactant: 353537
fast: false
reactant: 353513
name: R_aldehyde_dehydrogenase__2_methylbutanol__NAD_
type: Reaction
reactant: 353525
reversible: false
notes: GENE_ASSOCIATION: ( YBR145W or YMR303C or YDL168W or YGL256W or YOL086C ) PROTEIN_ASSOCIATION: ( Adh5 ) or ( Adh2 ) or ( Sfa1 ) or ( Adh4 ) or ( Adh1 ) SUBSYSTEM: S_Complex_Alcohol_Metabolism PROTEIN_CLASS:
product: 353562
product: 353549
kinetic law: 353574

294769
value: 0.0
type: LocalParameter

287346
reactant: 349422
notes: GENE_ASSOCIATION: YGL205W PROTEIN_ASSOCIATION: Pox1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 1.3.3.6
kinetic law: 349458
reversible: false
product: 349434
reactant: 349410
type: Reaction
fast: false
product: 349446
name: R_acyl_CoA_oxidase__octadecanoyl_CoA___peroxisomal

298723
value: -999999.0
type: LocalParameter

294236
value: 0.0
type: LocalParameter

303167
value: -999999.0
type: LocalParameter

422334
stoichiometry: 1.0
species: 283713
type: SpeciesReference

386971
stoichiometry: 1.0
species: 284001
type: SpeciesReference

291523
value: 0.0
type: LocalParameter

298266
value: 0.0
type: LocalParameter

364026
stoichiometry: 1.0
species: 283959
type: SpeciesReference

392800
stoichiometry: 1.0
species: 284669
type: SpeciesReference

387635
stoichiometry: 1.0
species: 285571
type: SpeciesReference

293060
value: 0.0
type: LocalParameter

298837
value: 999999.0
type: LocalParameter

385473
stoichiometry: 1.0
species: 284013
type: SpeciesReference

294237
value: 0.0
type: LocalParameter

422984
stoichiometry: 0.01
species: 285895
type: SpeciesReference

301517
value: 0.0
type: LocalParameter

288923
kinetic law: 379688
product: 379676
reactant: 379664
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Thymidine_exchange
type: Reaction

295296
value: 0.0
type: LocalParameter

298724
value: 999999.0
type: LocalParameter

352778
stoichiometry: 1.0
species: 285210
type: SpeciesReference

294851
value: 999999.0
type: LocalParameter

298267
value: -999999.0
type: LocalParameter

400203
stoichiometry: 1.0
species: 284840
type: SpeciesReference

287052
kinetic law: 343864
product: 343852
reactant: 343840
reactant: 343828
notes: GENE_ASSOCIATION: YGR282C PROTEIN_ASSOCIATION: Bgl2-e SUBSYSTEM: S_Starch_and_Sucrose_Metabolism PROTEIN_CLASS: 3.2.1.58
fast: false
reversible: false
name: R_Endo_1_3_beta_glucan_glucohydrase
type: Reaction

364464
stoichiometry: 1.0
species: 284987
type: SpeciesReference

359336
stoichiometry: 1.0
species: 284787
type: SpeciesReference

368373
stoichiometry: 1.0
species: 285751
type: SpeciesReference

300985
value: 0.0
type: LocalParameter

423440
stoichiometry: 1.0
species: 284808
type: SpeciesReference

359481
stoichiometry: 1.0
species: 284787
type: SpeciesReference

289053
reactant: 382260
reactant: 382272
notes: GENE_ASSOCIATION: ( YOR317W or YIL009W or YMR246W ) PROTEIN_ASSOCIATION: ( Faa1 ) or ( Faa3 ) or ( Faa4 ) SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.2.1.3
reactant: 382248
product: 382296
product: 382284
product: 382308
reversible: true
fast: false
type: Reaction
name: R_fatty_acid__CoA_ligase__tetradecanoate_
kinetic law: 382320

301623
value: 0.0
type: LocalParameter

298830
value: 999999.0
type: LocalParameter

287656
reactant: 356136
name: R_Adenosine_monophosphate_deaminase
product: 356148
product: 356160
kinetic law: 356172
fast: false
reactant: 356112
reversible: false
notes: GENE_ASSOCIATION: YML035C PROTEIN_ASSOCIATION: Amd1 SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS:
reactant: 356124
type: Reaction

382681
stoichiometry: 1.0
species: 283845
type: SpeciesReference

294448
value: 999999.0
type: LocalParameter

302317
value: 0.003023
type: LocalParameter

360113
stoichiometry: 1.0
species: 283608
type: SpeciesReference

298725
value: 0.0
type: LocalParameter

294347
value: 0.0
type: LocalParameter

287053
kinetic law: 343912
product: 343900
reactant: 343888
reactant: 343876
notes: GENE_ASSOCIATION: ( YOR190W or YDR261C or YLR300W ) PROTEIN_ASSOCIATION: ( Spr1-e ) or ( Exg2-e ) or ( Exg1-e ) SUBSYSTEM: S_Starch_and_Sucrose_Metabolism PROTEIN_CLASS: 3.2.1.58
fast: false
reversible: false
name: R_Exo_1_3_beta_glucan_glucohydrase
type: Reaction

439676
stoichiometry: 1.0
species: 284618
type: SpeciesReference

293392
value: 0.0
type: LocalParameter

381718
stoichiometry: 1.0
species: 284808
type: SpeciesReference

434729
stoichiometry: 1.0
species: 284757
type: SpeciesReference

300984
value: 0.0
type: LocalParameter

291417
value: 999999.0
type: LocalParameter

295293
value: 999999.0
type: LocalParameter

295140
value: 0.0
type: LocalParameter

299355
value: 999999.0
type: LocalParameter

413454
stoichiometry: 1.0
species: 282889
type: SpeciesReference

392378
stoichiometry: 1.0
species: 284529
type: SpeciesReference

299354
value: 0.0
type: LocalParameter

301624
value: 0.0
type: LocalParameter

402401
stoichiometry: 1.0
species: 283554
type: SpeciesReference

287974
kinetic law: 363531
product: 363519
product: 363507
product: 363495
reactant: 363458
reactant: 363483
reactant: 363470
reactant: 363446
name: R_Ceramide_3_synthase__24C_
fast: false
type: Reaction
notes: GENE_ASSOCIATION: YMR272C PROTEIN_ASSOCIATION: Scs7 SUBSYSTEM: S_Sphingolipid_Metabolism PROTEIN_CLASS:
reversible: false

293393
value: 0.0
type: LocalParameter

297705
value: 999999.0
type: LocalParameter

399662
stoichiometry: 1.0
species: 284766
type: SpeciesReference

302316
value: 0.0
type: LocalParameter

302429
value: 0.0
type: LocalParameter

413759
stoichiometry: 1.0
species: 285436
type: SpeciesReference

287050
constant: false
boundary condition: true
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
type: Species

390179
stoichiometry: 1.0
species: 283830
type: SpeciesReference

358679
stoichiometry: 1.0
species: 285511
type: SpeciesReference

303010
value: 0.0
type: LocalParameter

409325
stoichiometry: 1.0
species: 285790
type: SpeciesReference

291414
value: 0.0
type: LocalParameter

301625
value: 0.0
type: LocalParameter

426570
stoichiometry: 1.0
species: 284757
type: SpeciesReference

299353
value: 0.0
type: LocalParameter

298832
value: 0.0
type: LocalParameter

289051
product: 382224
product: 382212
reactant: 382175
reactant: 382188
product: 382200
reactant: 382163
kinetic law: 382236
reversible: true
name: R_fatty_acid__CoA_ligase__dodecanoate___peroxisomal
fast: false
notes: GENE_ASSOCIATION: YER015W PROTEIN_ASSOCIATION: Faa2-p SUBSYSTEM: S_Fatty_Acid__Biosynthesis PROTEIN_CLASS: 6.2.1.3
type: Reaction

352886
stoichiometry: 1.0
species: 283644
type: SpeciesReference

297708
value: 0.0
type: LocalParameter

302319
value: 0.0
type: LocalParameter

298727
value: 0.0
type: LocalParameter

419904
stoichiometry: 1.0
species: 285640
type: SpeciesReference

288926
kinetic law: 379724
product: 379712
reactant: 379700
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_Trehalose_exchange
type: Reaction

370538
stoichiometry: 1.0
species: 284787
type: SpeciesReference

385365
stoichiometry: 1.0
species: 284124
type: SpeciesReference

286261
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282870
name: M_Trehalose_C12H22O11
type: Species

291415
value: -999999.0
type: LocalParameter

422442
stoichiometry: 1.0
species: 285799
type: SpeciesReference

395927
stoichiometry: 1.0
species: 284787
type: SpeciesReference

294233
value: 1.983954
type: LocalParameter

287653
name: R_amidase
kinetic law: 356100
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: YDR242W PROTEIN_ASSOCIATION: Amd2 SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 3.5.1.4
product: 356076
fast: false
product: 356088
reactant: 356064
reactant: 356051

300981
value: 999999.0
type: LocalParameter

290418
reversible: true
product: 428906
reactant: 428870
reactant: 428882
product: 428894
kinetic law: 428918
notes: GENE_ASSOCIATION: YLR209C PROTEIN_ASSOCIATION: Pnp1 SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1
fast: false
name: R_purine_nucleoside_phosphorylase__Guanosine_
type: Reaction

287343
kinetic law: 349398
type: Reaction
product: 349374
reactant: 349350
product: 349386
notes: GENE_ASSOCIATION: YGL205W PROTEIN_ASSOCIATION: Pox1-p SUBSYSTEM: S_Fatty_Acid_Degradation PROTEIN_CLASS: 1.3.3.6
reversible: false
reactant: 349362
fast: false
name: R_acyl_CoA_oxidase__hexadecanoyl_CoA___peroxisomal

298833
value: 0.0
type: LocalParameter

297707
value: 0.0
type: LocalParameter

298728
value: 0.0
type: LocalParameter

293395
value: 999999.0
type: LocalParameter

291412
value: -8.35E-4
type: LocalParameter

288584
kinetic law: 375573
product: 375561
reactant: 375548
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS:
fast: false
reversible: true
name: R_L_Carnitine_exchange
type: Reaction

295290
value: 0.0
type: LocalParameter

303012
value: -0.011879
type: LocalParameter

300132
value: 999999.0
type: LocalParameter

293171
value: 0.0
type: LocalParameter

287056
fast: false
notes: GENE_ASSOCIATION: YGR247W PROTEIN_ASSOCIATION: Cpd1 SUBSYSTEM: S_Other PROTEIN_CLASS:
name: R_ADP_ribose_2_3_cyclic_phosphodiesterase
kinetic law: 344094
reversible: false
reactant: 344070
reactant: 344046
type: Reaction
product: 344082
reactant: 344058

367418
stoichiometry: 1.0
species: 284082
type: SpeciesReference

290752
reversible: false
kinetic law: 440005
notes: GENE_ASSOCIATION: YPL097W PROTEIN_ASSOCIATION: Msy1-m SUBSYSTEM: S_tRNA_charging PROTEIN_CLASS: 6.1.1.1
name: R_tyrosyl_tRNA_synthetase__mitochondrial
fast: false
product: 439980
reactant: 439932
type: Reaction
product: 439968
reactant: 439956
reactant: 439944
product: 439992

302312
value: -0.00297
type: LocalParameter

371590
stoichiometry: 1.0
species: 284304
type: SpeciesReference

298729
value: -999999.0
type: LocalParameter

294444
value: 0.0
type: LocalParameter

363736
stoichiometry: 1.0
species: 286549
type: SpeciesReference

287057
kinetic law: 344130
product: 344118
reactant: 344106
notes: GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Mitochondrial PROTEIN_CLASS:
fast: false
reversible: true
name: R_2_Dehydro_3_deoxy_D_arabino_heptonate7_phohsphate_mitochondrial_transport_via_diffusion
type: Reaction

286267
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 282871
type: Species

351259
stoichiometry: 1.0
species: 285005
type: SpeciesReference

287878
name: R_C_4_sterol_methyl_oxidase__4_4_dimethylzymosterol_
reactant: 361274
reactant: 361286
product: 361334
product: 361310
reactant: 361261
kinetic law: 361346
fast: false
type: Reaction
reversible: false
notes: GENE_ASSOCIATION: YGR060W PROTEIN_ASSOCIATION: Erg25 SUBSYSTEM: S_Sterol_Metabolism PROTEIN_CLASS:
product: 361322
reactant: 361298