927802
stoichiometry: 2.0
species: 891591
type: SpeciesReference

932887
stoichiometry: 1.0
species: 891483
type: SpeciesReference

929952
stoichiometry: 1.0
species: 891664
type: SpeciesReference

968871
stoichiometry: 1.0
species: 896378
type: SpeciesReference

945918
stoichiometry: 1.0
species: 896680
type: SpeciesReference

981977
stoichiometry: 1.0
species: 889851
type: SpeciesReference

007918
stoichiometry: 1.0
species: 902716
type: SpeciesReference

978482
stoichiometry: 1.0
species: 895508
type: SpeciesReference

973205
stoichiometry: 1.0
species: 893683
type: SpeciesReference

884439
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Coenzyme A_C21H32N7O16P3S
type: Species

950967
stoichiometry: 1.0
species: 885092
type: SpeciesReference

921362
stoichiometry: 1.0
species: 880486
type: SpeciesReference

959593
stoichiometry: 1.0
species: 882030
type: SpeciesReference

980596
stoichiometry: 1.0
species: 896330
type: SpeciesReference

939655
stoichiometry: 1.0
species: 897443
type: SpeciesReference

933515
stoichiometry: 1.0
species: 903644
type: SpeciesReference

911866
stoichiometry: 1.0
species: 903452
type: SpeciesReference

989521
stoichiometry: 1.0
species: 903800
type: SpeciesReference

876668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: _10-Formyltetrahydrofolate_C20H21N7O7
type: Species

954167
stoichiometry: 1.0
species: 897864
type: SpeciesReference

901233
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Sarcosine_C3H7NO2
type: Species

936988
stoichiometry: 1.0
species: 889358
type: SpeciesReference

930520
stoichiometry: 2.0
species: 887082
type: SpeciesReference

907929
stoichiometry: 1.0
species: 889190
type: SpeciesReference

908469
type: Reaction
notes: R_ICDHyrm subsystem: Citric Acid Cycle R_ICDHyrm equation: [m] : icit + nadp <==> akg + co2 + nadph
is: http://identifiers.org/ec-code/1.1.1.42
product: 978702
is: ENSPTRG00000007446.3
fast: false
reactant: 978666
product: 978690
name: Isocitrate dehydrogenase (NADP+)
product: 978714
reversible: true
reactant: 978678

952225
stoichiometry: 1.0
species: 880462
type: SpeciesReference

884000
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: chitin_C24H41N3O16
type: Species

908249
stoichiometry: 1.0
species: 900002
type: SpeciesReference

897371
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

879138
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-Methoxyindoleacetate_C11H10NO3
type: Species

994623
stoichiometry: 2.0
species: 891591
type: SpeciesReference

992316
stoichiometry: 1.0
species: 891604
type: SpeciesReference

892220
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Homoserine_C4H9NO3
type: Species

981504
stoichiometry: 1.0
species: 882102
type: SpeciesReference

909529
stoichiometry: 1.0
species: 884427
type: SpeciesReference

882937
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: (R)-3-Hydroxybutanoate_C4H7O3
type: Species

906655
fast: false
product: 960787
product: 960811
reactant: 960763
product: 960799
notes: R_F6Tg subsystem: N-Glycan Biosynthesis R_F6Tg equation: [g] : gdpfuc + n2m2masn --> fn2m2masn + gdp + h
reversible: false
name: glycoprotein 6-alpha-L-fucosyltransferase
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.68
reactant: 960775
is: ENSPTRG00000022821.3

888127
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Estrone_C18H22O2
type: Species

911867
is: ENSPTRG00000031285.1
is: ENSPTRG00000000280.2
reversible: false
product: 008646
product: 008634
is: ENSPTRG00000000279.3
notes: R_PLA2_2e subsystem: Glycerophospholipid Metabolism R_PLA2_2e equation: [e] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
reactant: 008609
is: ENSPTRG00000000276.1
is: ENSPTRG00000000278.3
product: 008658
name: phospholipase A2
is: http://identifiers.org/ec-code/3.1.1.4
is: ENSPTRG00000005530.3
reactant: 008622
is: ENSPTRG00000016362.2
type: Reaction
fast: false

982133
stoichiometry: 1.0
species: 886576
type: SpeciesReference

925031
stoichiometry: 1.0
species: 891555
type: SpeciesReference

890313
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Glutamate 5-semialdehyde_C5H9NO3
type: Species

924982
stoichiometry: 1.0
species: 891591
type: SpeciesReference

901234
is: ENSPTRG00000015024.4
reactant: 914994
reversible: true
is: ENSPTRG00000022429.5
is: http://identifiers.org/ec-code/2.2.1.1
product: 915054
reactant: 915006
is: ENSPTRG00000016563.2
product: 915042
reactant: 915018
product: 915030
fast: false
type: Reaction
notes: R_TKT2 subsystem: Pentose Phosphate Pathway R_TKT2 equation: [c] : e4p + xu5p-D <==> f6p + g3p R_TKT1 subsystem: Pentose Phosphate Pathway R_TKT1 equation: [c] : r5p + xu5p-D <==> g3p + s7p

972964
stoichiometry: 1.0
species: 893466
type: SpeciesReference

959381
stoichiometry: 1.0
species: 899287
type: SpeciesReference

898648
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2
type: Species

916405
stoichiometry: 1.0
species: 901862
type: SpeciesReference

904826
type: Reaction
name: L-glutamate secretion via secretory vesicle (ATP driven)
reactant: 943965
product: 943990
reactant: 943978
product: 944014
product: 944002
fast: false
product: 944026
reversible: false
reactant: 943952
is: ENSPTRG00000003444.4
is: ENSPTRG00000011294.3
notes: R_GLUVESSEC subsystem: Transport, Extracellular R_GLUVESSEC equation: atp[c] + glu-L[c] + h2o[c] --> adp[c] + glu-L[e] + h[c] + pi[c]
is: ENSPTRG00000005344.4

909833
stoichiometry: 1.0
species: 893394
type: SpeciesReference

892437
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 19_C43H67N2O42S2
type: Species

995720
stoichiometry: 1.0
species: 903452
type: SpeciesReference

928324
stoichiometry: 1.0
species: 885888
type: SpeciesReference

993247
stoichiometry: 1.0
species: 892317
type: SpeciesReference

889190
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein)_C70H117N2O55X
type: Species

975570
stoichiometry: 2.0
species: 891616
type: SpeciesReference

908248
reversible: false
type: Reaction
product: 975798
product: 975822
reactant: 975774
product: 975810
is: ENSPTRG00000014232.4
fast: false
reactant: 975786
reactant: 975762
notes: R_PI3PP subsystem: Inositol Phosphate Metabolism R_PI3PP equation: [c] : h2o + pail3p_hs --> pail_hs + pi R_PI35P3P subsystem: Inositol Phosphate Metabolism R_PI35P3P equation: [c] : h2o + pail35p_hs --> pail5p_hs + pi

892146
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
type: Species

890216
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Glucarate_C6H8O8
type: Species

922371
stoichiometry: 1.0
species: 896643
type: SpeciesReference

912699
stoichiometry: 1.0
species: 900739
type: SpeciesReference

980730
stoichiometry: 3.0
species: 891652
type: SpeciesReference

929263
stoichiometry: 1.0
species: 901970
type: SpeciesReference

877770
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

927163
stoichiometry: 1.0
species: 897636
type: SpeciesReference

956726
stoichiometry: 1.0
species: 884171
type: SpeciesReference

983543
stoichiometry: 1.0
species: 899166
type: SpeciesReference

931294
stoichiometry: 1.0
species: 882457
type: SpeciesReference

928685
stoichiometry: 1.0
species: 904537
type: SpeciesReference

940031
stoichiometry: 1.0
species: 877336
type: SpeciesReference

900617
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Pyridoxamine 5'-phosphate_C8H12N2O5P
type: Species

969889
stoichiometry: 1.0
species: 904320
type: SpeciesReference

976101
stoichiometry: 1.0
species: 891555
type: SpeciesReference

955544
stoichiometry: 1.0
species: 882090
type: SpeciesReference

957873
stoichiometry: 1.0
species: 882781
type: SpeciesReference

000201
stoichiometry: 1.0
species: 899396
type: SpeciesReference

969280
stoichiometry: 1.0
species: 885428
type: SpeciesReference

883386
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: cAMP_C10H11N5O6P
type: Species

904825
stoichiometry: 1.0
species: 891591
type: SpeciesReference

963506
stoichiometry: 5.0
species: 882673
type: SpeciesReference

886781
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dIDP_C10H11N4O10P2
type: Species

909215
stoichiometry: 1.0
species: 901005
type: SpeciesReference

905777
product: 952974
fast: false
is: http://identifiers.org/ec-code/3.5.4.12
product: 952962
type: Reaction
reactant: 952950
notes: R_DCMPDA subsystem: Pyrimidine Catabolism R_DCMPDA equation: [c] : dcmp + h + h2o <==> dump + nh4
is: ENSPTRG00000016624.3
name: dCMP deaminase
reactant: 952938
reactant: 952926
reversible: true

961318
stoichiometry: 3.0
species: 891483
type: SpeciesReference

955604
stoichiometry: 1.0
species: 900002
type: SpeciesReference

891700
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: hyaluronan_C28H40N2O22
type: Species

911710
stoichiometry: 2.0
species: 881198
type: SpeciesReference

895177
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Leukotriene B4_C20H31O4
type: Species

954227
stoichiometry: 1.0
species: 891531
type: SpeciesReference

900618
product: 910572
reactant: 910524
name: choline phosphotransferase
reactant: 910536
product: 910548
notes: R_CEPTC subsystem: Glycerophospholipid Metabolism R_CEPTC equation: [c] : cdpchol + dag_hs --> cmp + h + pchol_hs
is: ENSPTRG00000005354.4
product: 910560
reversible: false
type: Reaction
fast: false

976645
stoichiometry: 3.0
species: 886069
type: SpeciesReference

976934
stoichiometry: 3.0
species: 886275
type: SpeciesReference

958974
stoichiometry: 2.0
species: 891591
type: SpeciesReference

990734
stoichiometry: 2.0
species: 897552
type: SpeciesReference

908571
stoichiometry: 3.0
species: 881282
type: SpeciesReference

899021
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: _3'-Phosphoadenylyl sulfate_C10H11N5O13P2S
type: Species

999488
stoichiometry: 1.0
species: 891676
type: SpeciesReference

946230
stoichiometry: 1.0
species: 896885
type: SpeciesReference

001485
stoichiometry: 1.0
species: 893948
type: SpeciesReference

948466
stoichiometry: 1.0
species: 882853
type: SpeciesReference

967496
stoichiometry: 1.0
species: 884391
type: SpeciesReference

907605
reversible: false
reactant: 968244
product: 968316
product: 968292
product: 968256
reactant: 968232
reactant: 968208
notes: R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp R_GLCNACT1g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT1g equation: [g] : cs,hs_linkage + uacgam --> h + hs_pre1 + udp
fast: false
product: 968328
reactant: 968220
is: ENSPTRG00000020124.3
product: 968280
reactant: 968196
product: 968304
reactant: 968184
type: Reaction
product: 968268

883167
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Biotin_C10H15N2O3S
type: Species

002859
stoichiometry: 2.0
species: 897564
type: SpeciesReference

916560
stoichiometry: 1.0
species: 895338
type: SpeciesReference

004777
stoichiometry: 25.0
species: 891591
type: SpeciesReference

905380
product: 948002
product: 947978
type: Reaction
product: 947990
is: ENSPTRG00000000779.4
reactant: 947917
reactant: 947941
notes: R_DHCR243r subsystem: Cholesterol Metabolism R_DHCR243r equation: [r] : dsmsterol + fadh2 --> chsterol + fad R_DHCR242r subsystem: Cholesterol Metabolism R_DHCR242r equation: [r] : chlstol + fadh2 --> fad + lthstrl R_DHCR241r subsystem: Cholesterol Metabolism R_DHCR241r equation: [r] : fadh2 + zymst --> fad + zymstnl
fast: false
reactant: 947953
reactant: 947929
product: 947966
reversible: false

955244
stoichiometry: 12.0
species: 891483
type: SpeciesReference

911711
reversible: false
product: 007627
product: 007590
reactant: 007566
reactant: 007554
product: 007602
is: ENSPTRG00000001415.4
is: ENSPTRG00000001416.3
notes: R_GBAl subsystem: Sphingolipid Metabolism R_GBAl equation: [l] : gluside_hs + h2o --> crm_hs + glc-D R_GBA subsystem: Sphingolipid Metabolism R_GBA equation: [c] : gluside_hs + h2o --> crm_hs + glc-D
type: Reaction
reactant: 007578
fast: false
product: 007615
reactant: 007542
is: http://identifiers.org/ec-code/3.2.1.45

911442
stoichiometry: 1.0
species: 896487
type: SpeciesReference

890782
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: glycogen, structure 5 (glycogenin-2[1,4-Glc])_C12H21O11X
type: Species

922965
stoichiometry: 18.0
species: 903488
type: SpeciesReference

900328
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Prostaglandin E1_C20H33O5
type: Species

914209
stoichiometry: 1.0
species: 901886
type: SpeciesReference

919462
stoichiometry: 1.0
species: 891326
type: SpeciesReference

906652
stoichiometry: 5.0
species: 891604
type: SpeciesReference

905275
stoichiometry: 1.0
species: 878301
type: SpeciesReference

896970
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Methylamine_C1H6N
type: Species

944617
stoichiometry: 15.0
species: 896427
type: SpeciesReference

909213
notes: R_ACTNMO subsystem: Pyruvate Metabolism R_ACTNMO equation: [c] : acetone + h + nadph + o2 --> acetol + h2o + nadp R_ETOHMO subsystem: Glycolysis/Gluconeogenesis R_ETOHMO equation: [c] : etoh + h + nadph + o2 --> acald + (2) h2o + nadp R_P4502E1 subsystem: CYP Metabolism R_P4502E1 equation: [c] : 4nph + h + nadph + o2 --> 24nph + h2o + nadp R_ACTLMO subsystem: Pyruvate Metabolism R_ACTLMO equation: [c] : acetol + h + nadph + o2 --> (2) h2o + mthgxl + nadp
type: Reaction
reactant: 983675
reversible: false
reactant: 983639
product: 983784
product: 983723
is: ENSPTRG00000023919.3
reactant: 983699
reactant: 983687
reactant: 983651
product: 983747
product: 983772
fast: false
reactant: 983663
is: ENSPTRG00000003099.2
product: 983735
reactant: 983711
product: 983760

953832
stoichiometry: 1.0
species: 900316
type: SpeciesReference

972493
stoichiometry: 1.0
species: 880219
type: SpeciesReference

909525
reversible: false
product: 986603
reactant: 986579
fast: false
product: 986615
type: Reaction
is: http://identifiers.org/ec-code/1.14.14.1
notes: R_MELATNOX subsystem: Tryptophan metabolism R_MELATNOX equation: [c] : h + melatn + nadph + o2 --> 6hoxmelatn + h2o + nadp
reactant: 986555
product: 986627
name: Melatonin:NADP oxidoreductase
reactant: 986591
reactant: 986567
is: ENSPTRG00000007280.3
is: ENSPTRG00000007281.3

884222
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: CMP_C9H12N3O8P
type: Species

898370
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: octanoate (n-C8:0)_C8H15O2
type: Species

893514
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 15_C160H257N11O140S8
type: Species

893115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Isoleucine_C6H13NO2
type: Species

920843
stoichiometry: 1.0
species: 889298
type: SpeciesReference

878072
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _3-Oxooctadecanoyl-CoA_C39H64N7O18P3S
type: Species

009839
stoichiometry: 1.0
species: 880945
type: SpeciesReference

991809
stoichiometry: 1.0
species: 897347
type: SpeciesReference

899323
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2
type: Species

002631
stoichiometry: 1.0
species: 901934
type: SpeciesReference

987843
stoichiometry: 1.0
species: 896885
type: SpeciesReference

913362
stoichiometry: 1.0
species: 904091
type: SpeciesReference

910355
stoichiometry: 1.0
species: 898792
type: SpeciesReference

927584
stoichiometry: 1.0
species: 892958
type: SpeciesReference

946798
stoichiometry: 1.0
species: 878643
type: SpeciesReference

876813
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _13-cis-retinoate_C20H27O2
type: Species

901402
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Serine_C3H7NO3
type: Species

997449
stoichiometry: 1.0
species: 876886
type: SpeciesReference

991953
stoichiometry: 3.0
species: 898491
type: SpeciesReference

910632
stoichiometry: 1.0
species: 898768
type: SpeciesReference

900329
fast: false
type: Reaction
is: ENSPTRG00000014621.4
product: 908121
is: ENSPTRG00000004506.4
reactant: 908109
product: 908133
reactant: 908097
notes: R_ABUTt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_ABUTt4_LPAREN_2_RPAREN_r equation: _4abut[e] + (2) na1[e] <==> 4abut[c] + (2) na1[c]
reversible: true
is: ENSPTRG00000014622.2
name: _4-aminobutyrate reversible transport in via sodium symport (1:2)

947725
stoichiometry: 20.0
species: 903488
type: SpeciesReference

948171
stoichiometry: 1.0
species: 895556
type: SpeciesReference

972385
stoichiometry: 1.0
species: 882090
type: SpeciesReference

882188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Androstenedione_C19H26O2
type: Species

885284
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 5_C31H47NO35S3
type: Species

984808
stoichiometry: 1.0
species: 877806
type: SpeciesReference

002438
stoichiometry: 1.0
species: 890506
type: SpeciesReference

930134
stoichiometry: 1.0
species: 877613
type: SpeciesReference

956473
stoichiometry: 1.0
species: 886021
type: SpeciesReference

908573
product: 979437
is: ENSPTRG00000021451.3
is: http://identifiers.org/ec-code/3.6.1.43
notes: R_DOLDPP_Ler subsystem: N-Glycan Biosynthesis R_DOLDPP_Ler equation: [r] : (0.1) doldp_L + h2o --> (0.1) dolp_L + h + pi R_DOLDPP_Uer subsystem: N-Glycan Biosynthesis R_DOLDPP_Uer equation: [r] : (0.1) doldp_U + h2o --> (0.1) dolp_U + h + pi
product: 979413
reversible: false
type: Reaction
reactant: 979389
product: 979450
product: 979425
reactant: 979401
reactant: 979377
fast: false

943463
stoichiometry: 3.0
species: 899021
type: SpeciesReference

907281
reactant: 964400
product: 964424
product: 964448
is: ENSPTRG00000001685.3
name: phosphatidylinositol N-acetylglucosaminyltransferase
type: Reaction
is: http://identifiers.org/ec-code/2.4.1.198
fast: false
is: ENSPTRG00000021684.5
is: ENSPTRG00000013897.4
reactant: 964412
notes: R_PIACGT subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_PIACGT equation: [c] : pail_hs + uacgam --> acgpail_hs + h + udp
reversible: false
is: ENSPTRG00000007545.3
is: ENSPTRG00000006466.2
product: 964436

001881
stoichiometry: 1.0
species: 902920
type: SpeciesReference

907603
stoichiometry: 1.0
species: 881463
type: SpeciesReference

904525
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Xyl-L-Ser (protein)_C5H9O4X
type: Species

932150
stoichiometry: 4.0
species: 901549
type: SpeciesReference

957137
stoichiometry: 1.0
species: 900472
type: SpeciesReference

909837
product: 990541
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PDE4n subsystem: Nucleotides R_PDE4n equation: [n] : 35cgmp + h2o --> gmp + h
product: 990529
reactant: 990492
reactant: 990480
reversible: false
type: Reaction
fast: false
is: ENSPTRG00000013946.4
product: 990553
product: 990565
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 990517
reactant: 990505

941131
stoichiometry: 1.0
species: 899530
type: SpeciesReference

979281
stoichiometry: 1.0
species: 885888
type: SpeciesReference

995939
stoichiometry: 1.0
species: 897395
type: SpeciesReference

997728
stoichiometry: 1.0
species: 882685
type: SpeciesReference

004341
stoichiometry: 1.0
species: 884814
type: SpeciesReference

943390
stoichiometry: 3.0
species: 891664
type: SpeciesReference

904670
product: 943029
type: Reaction
product: 943017
is: http://identifiers.org/ec-code/1.8.1.7
reactant: 942957
reactant: 943005
reactant: 942981
reactant: 942993
product: 943041
is: ENSPTRG00000011165.3
reactant: 942945
reversible: false
notes: R_GTHO subsystem: Glutamate metabolism R_GTHO equation: [c] : gthox + h + nadph --> (2) gthrd + nadp R_GTHOm subsystem: Glutamate metabolism R_GTHOm equation: [m] : gthox + h + nadph --> (2) gthrd + nadp
reactant: 942969
fast: false
product: 943053

909736
stoichiometry: 3.0
species: 897419
type: SpeciesReference

989979
stoichiometry: 1.0
species: 894615
type: SpeciesReference

009815
stoichiometry: 8.0
species: 891616
type: SpeciesReference

993886
stoichiometry: 1.0
species: 884073
type: SpeciesReference

963249
stoichiometry: 3.0
species: 891640
type: SpeciesReference

903850
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.137
reactant: 935277
is: ENSPTRG00000009983.3
fast: false
product: 935301
reactant: 935265
product: 935313
product: 935325
product: 935289
reactant: 935253
notes: R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs
reversible: false

962585
stoichiometry: 2.0
species: 891483
type: SpeciesReference

952780
stoichiometry: 1.0
species: 888418
type: SpeciesReference

925644
stoichiometry: 1.0
species: 885550
type: SpeciesReference

941772
stoichiometry: 1.0
species: 887691
type: SpeciesReference

962151
stoichiometry: 1.0
species: 899795
type: SpeciesReference

990467
stoichiometry: 1.0
species: 894104
type: SpeciesReference

915766
stoichiometry: 1.0
species: 891591
type: SpeciesReference

960642
stoichiometry: 1.0
species: 898768
type: SpeciesReference

903440
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
type: Species

978738
stoichiometry: 1.0
species: 891495
type: SpeciesReference

910630
product: 995939
is: http://identifiers.org/ec-code/1.5.1.2
notes: R_PRO1x subsystem: Arginine and Proline Metabolism R_PRO1x equation: [c] : nad + pro-L --> 1pyr5c + (2) h + nadh R_PROD2 subsystem: Arginine and Proline Metabolism R_PROD2 equation: [c] : fad + pro-L --> 1pyr5c + fadh2 + h
reversible: false
reactant: 995878
type: Reaction
product: 995914
reactant: 995866
product: 995926
is: http://identifiers.org/ec-code/1.5.99.8
is: ENSPTRG00000010869.4
fast: false
reactant: 995890
product: 995902

894807
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate II biosynthesis, precursor 4_C61H99N5O43X
type: Species

937823
stoichiometry: 1.0
species: 884391
type: SpeciesReference

941540
stoichiometry: 1.0
species: 889996
type: SpeciesReference

937230
stoichiometry: 1.0
species: 890264
type: SpeciesReference

903742
product: 934505
notes: R_ADPT subsystem: Salvage Pathway R_ADPT equation: [c] : ade + prpp --> amp + ppi
reactant: 934481
reactant: 934493
name: adenine phosphoribosyltransferase
product: 934517
fast: false
is: ENSPTRG00000008466.4
is: http://identifiers.org/ec-code/2.4.2.7
type: Reaction
reversible: false

905770
stoichiometry: 1.0
species: 892146
type: SpeciesReference

905384
stoichiometry: 1.0
species: 892377
type: SpeciesReference

916827
stoichiometry: 1.0
species: 887873
type: SpeciesReference

880619
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO
type: Species

903441
product: 932271
reactant: 932259
notes: R_PGI subsystem: Glycolysis/Gluconeogenesis R_PGI equation: [c] : g6p <==> f6p
is: ENSPTRG00000010816.4
is: http://identifiers.org/ec-code/5.3.1.9
fast: false
reversible: true
name: glucose-6-phosphate isomerase
type: Reaction

893936
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 8_C194H311N13O171S10
type: Species

939235
stoichiometry: 1.0
species: 881366
type: SpeciesReference

004089
stoichiometry: 2.0
species: 884934
type: SpeciesReference

913470
stoichiometry: 1.0
species: 903403
type: SpeciesReference

968496
stoichiometry: 1.0
species: 900496
type: SpeciesReference

980354
stoichiometry: 1.0
species: 891591
type: SpeciesReference

883058
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Biliverdin_C33H32N4O6
type: Species

952890
stoichiometry: 1.0
species: 882090
type: SpeciesReference

953724
stoichiometry: 1.0
species: 902078
type: SpeciesReference

010551
stoichiometry: 3.0
species: 891676
type: SpeciesReference

003716
stoichiometry: 1.0
species: 897201
type: SpeciesReference

900991
product: 912977
reactant: 912843
product: 913037
product: 913013
product: 913025
product: 912989
reactant: 912892
reversible: false
is: http://identifiers.org/ec-code/3.1.6.2
reactant: 912880
reactant: 912905
type: Reaction
reactant: 912819
reactant: 912831
product: 912929
product: 912941
reactant: 912856
notes: R_STS2 subsystem: Steroid Metabolism R_STS2 equation: [c] : estrones + h2o --> estrone + h + so4 R_STS3 subsystem: Steroid Metabolism R_STS3 equation: [c] : chsterols + h2o --> chsterol + h + so4 R_STS4 subsystem: Steroid Metabolism R_STS4 equation: [c] : h2o + prgnlones --> h + prgnlone + so4 R_STS3r subsystem: Steroid Metabolism R_STS3r equation: [r] : chsterols + h2o --> chsterol + h + so4 R_STS4r subsystem: Steroid Metabolism R_STS4r equation: [r] : h2o + prgnlones --> h + prgnlone + so4 R_STS1r subsystem: Steroid Metabolism R_STS1r equation: [r] : dheas + h2o --> dhea + h + so4 R_STS1 subsystem: Steroid Metabolism R_STS1 equation: [c] : dheas + h2o --> dhea + h + so4 R_STS2r subsystem: Steroid Metabolism R_STS2r equation: [r] : estrones + h2o --> estrone + h + so4
product: 913061
is: ENSPTRG00000021640.3
reactant: 912868
product: 912965
product: 913001
product: 912953
reactant: 912807
reactant: 912917
product: 913049
fast: false

916103
stoichiometry: 1.0
species: 899530
type: SpeciesReference

990843
stoichiometry: 2.0
species: 897492
type: SpeciesReference

933990
stoichiometry: 1.0
species: 881282
type: SpeciesReference

911447
product: 004777
reactant: 004606
reactant: 004521
product: 004765
product: 004741
type: Reaction
modifier: 004971
is: http://identifiers.org/ec-code/1.2.1.3
is: http://identifiers.org/ec-code/1.2.1.5
product: 004704
product: 004666
product: 004801
modifier: 004838
product: 004692
reactant: 004654
notes: R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_34DHPLACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHPLACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhpac + h2o + nadp <==> 34dhpha + (2) h + nadph R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_34DHXMANDACOX subsystem: Tyrosine metabolism R_34DHXMAND…
reactant: 004630
reactant: 004509
reactant: 004569
reactant: 004594
product: 004680
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 004533
fast: false
reactant: 004618
is: http://identifiers.org/ec-code/1.2.1.39
is: http://identifiers.org/ec-code/1.2.1.4
product: 004813
modifier: 004851
modifier: 004947
modifier: 004923
product: 004728
is: ENSPTRG00000008874.4
reactant: 004557
reactant: 004582
modifier: 004875
product: 004716
modifier: 004899
product: 004789
modifier: 004935
modifier: 004911
product: 004753
modifier: 004826
reactant: 004642
modifier: 004983
reversible: false
modifier: 004863
modifier: 004959
modifier: 004887
reactant: 004545

954459
stoichiometry: 1.0
species: 878325
type: SpeciesReference

905272
modifier: 946495
modifier: 946471
modifier: 946568
modifier: 946447
notes: R_PUNP5 subsystem: Purine Catabolism R_PUNP5 equation: [c] : ins + pi <==> hxan + r1p R_PUNP3 subsystem: Purine Catabolism R_PUNP3 equation: [c] : gsn + pi <==> gua + r1p R_PUNP4 subsystem: Purine Catabolism R_PUNP4 equation: [c] : dgsn + pi <==> 2dr1p + gua R_PUNP2 subsystem: Purine Catabolism R_PUNP2 equation: [c] : dad-2 + pi <==> 2dr1p + ade R_PUNP1 subsystem: Nucleotides R_PUNP1 equation: [c] : adn + pi <==> ade + r1p R_PUNP7 subsystem: Nucleotides R_PUNP7 equation: [c] : pi + xtsn <==> r1p + xan R_PUNP6 subsystem: Purine Catabolism R_PUNP6 equation: [c] : din + pi <==> 2dr1p + hxan R_DURIPP subsystem: Nucleotides R_DURIPP equation: [c] : duri + pi <==> 2dr1p + ura R_PNP subsystem: NAD Metabolism R_PNP equation: [c] : pi + rnam <==> h + ncam + r1p R_NP1 subsystem: NAD Metabolism R_NP1 equation: [c] : h + nac + r1p --> nicrns + pi
modifier: 946434
modifier: 946531
modifier: 946362
reactant: 946302
type: Reaction
modifier: 946580
modifier: 946386
modifier: 946483
modifier: 946519
product: 946338
reactant: 946314
modifier: 946374
modifier: 946398
product: 946350
reversible: false
reactant: 946326
is: ENSPTRG00000006095.4
fast: false
modifier: 946507
modifier: 946410
modifier: 946459
is: http://identifiers.org/ec-code/2.4.2.1
modifier: 946555
modifier: 946543
modifier: 946422

901598
name: choline dehydrogenase (FAD acceptor), mitochondrial
reactant: 916284
is: http://identifiers.org/ec-code/1.1.99.1
fast: false
reactant: 916272
reversible: false
notes: R_CHOLD2m subsystem: Glycine, Serine, and Threonine Metabolism R_CHOLD2m equation: [m] : chol + fad --> betald + fadh2
type: Reaction
product: 916308
is: ENSPTRG00000015027.2
product: 916296

995296
stoichiometry: 1.0
species: 883143
type: SpeciesReference

879679
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Cystine_C6H12N2O4S2
type: Species

906302
stoichiometry: 1.0
species: 900836
type: SpeciesReference

989762
stoichiometry: 19.0
species: 903452
type: SpeciesReference

987097
stoichiometry: 1.0
species: 880921
type: SpeciesReference

961005
stoichiometry: 1.0
species: 892704
type: SpeciesReference

982686
stoichiometry: 2.0
species: 878421
type: SpeciesReference

898756
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2
type: Species

893006
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Indole-3-acetaldehyde_C10H9NO
type: Species

961739
stoichiometry: 1.0
species: 903632
type: SpeciesReference

951911
stoichiometry: 1.0
species: 888309
type: SpeciesReference

896861
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1D-myo-Inositol 1-phosphate_C6H11O9P
type: Species

884331
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: CO2_CO2
type: Species

941698
stoichiometry: 10.0
species: 882817
type: SpeciesReference

976717
stoichiometry: 3.0
species: 891339
type: SpeciesReference

937931
stoichiometry: 1.0
species: 900885
type: SpeciesReference

982025
stoichiometry: 3.0
species: 899530
type: SpeciesReference

910788
stoichiometry: 2.0
species: 891591
type: SpeciesReference

894092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 18_C163H262N11O132S5X
type: Species

997837
stoichiometry: 1.0
species: 890506
type: SpeciesReference

994419
stoichiometry: 2.0
species: 896004
type: SpeciesReference

897792
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: NMN_C11H14N2O8P
type: Species

912120
notes: R_SPRMS subsystem: Urea cycle/amino group metabolism R_SPRMS equation: [c] : ametam + spmd --> 5mta + h + sprm
is: http://identifiers.org/ec-code/2.5.1.22
reversible: false
type: Reaction
reactant: 010750
product: 010774
product: 010762
name: spermine synthase
product: 010786
reactant: 010738
is: ENSPTRG00000021736.4
fast: false

876923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _18 hydroxy arachidonic acid_C20H31O3
type: Species

962994
stoichiometry: 1.0
species: 889082
type: SpeciesReference

947617
stoichiometry: 1.0
species: 894615
type: SpeciesReference

978846
stoichiometry: 2.0
species: 882781
type: SpeciesReference

915187
stoichiometry: 1.0
species: 881258
type: SpeciesReference

910354
fast: false
type: Reaction
reactant: 993307
notes: R_GLYAMDTRc subsystem: Urea cycle/amino group metabolism R_GLYAMDTRc equation: [c] : arg-L + gly <==> gudac + orn
is: ENSPTRG00000007033.5
reversible: true
reactant: 993295
is: http://identifiers.org/ec-code/2.1.4.1
product: 993331
name: glycine amidinotransferase (c)
product: 993319

888237
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Ethanolamine_C2H8NO
type: Species

936158
stoichiometry: 1.0
species: 900764
type: SpeciesReference

893864
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 40_C40H68N2O31
type: Species

002787
stoichiometry: 1.0
species: 883783
type: SpeciesReference

920915
stoichiometry: 4.0
species: 897273
type: SpeciesReference

908353
stoichiometry: 1.0
species: 891483
type: SpeciesReference

903740
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: UMP_C9H11N2O9P
type: Species

909369
product: 984941
notes: R_SELCYSTGL subsystem: Selenoamino acid metabolism R_SELCYSTGL equation: [c] : h2o + selcyst --> 2obut + nh4 + selcys R_CYSTGL subsystem: Cysteine Metabolism R_CYSTGL equation: [c] : cyst-L + h2o --> 2obut + cys-L + nh4
reversible: false
type: Reaction
is: http://identifiers.org/ec-code/4.4.1.1
fast: false
reactant: 984905
product: 984966
reactant: 984929
product: 984978
product: 984954
reactant: 984917
is: ENSPTRG00000000854.1

994563
stoichiometry: 1.0
species: 901549
type: SpeciesReference

984917
stoichiometry: 1.0
species: 901342
type: SpeciesReference

919570
stoichiometry: 1.0
species: 903403
type: SpeciesReference

906544
stoichiometry: 1.0
species: 903476
type: SpeciesReference

900993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Ribose_C5H10O5
type: Species

965011
stoichiometry: 1.0
species: 878012
type: SpeciesReference

953400
stoichiometry: 2.0
species: 891591
type: SpeciesReference

881439
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: adrenyl coenzyme A_C43H66N7O17P3S
type: Species

895024
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Lactaldehyde_C3H6O2
type: Species

968304
stoichiometry: 1.0
species: 892765
type: SpeciesReference

932379
stoichiometry: 1.0
species: 891242
type: SpeciesReference

901513
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-sulfolactate_C3H4O6S
type: Species

937388
stoichiometry: 3.0
species: 891591
type: SpeciesReference

915875
stoichiometry: 4.0
species: 891591
type: SpeciesReference

006127
stoichiometry: 1.0
species: 893247
type: SpeciesReference

957029
stoichiometry: 1.0
species: 901970
type: SpeciesReference

916719
stoichiometry: 1.0
species: 904067
type: SpeciesReference

960799
stoichiometry: 1.0
species: 888599
type: SpeciesReference

956581
stoichiometry: 1.0
species: 892281
type: SpeciesReference

947098
stoichiometry: 1.0
species: 878373
type: SpeciesReference

941881
stoichiometry: 10.0
species: 881258
type: SpeciesReference

908352
product: 976790
product: 976850
reactant: 976645
product: 976874
reactant: 976681
reactant: 976741
product: 976862
product: 976922
product: 976898
reactant: 976778
reactant: 976619
reactant: 976580
reactant: 976765
product: 976886
product: 976910
reactant: 976669
product: 976946
reactant: 976729
product: 976934
reactant: 976657
reversible: true
reactant: 976554
reactant: 976693
fast: false
reactant: 976753
reactant: 976593
reactant: 976717
reactant: 976541
notes: R_CYTK5 subsystem: Nucleotides R_CYTK5 equation: [c] : ctp + dcmp <==> cdp + dcdp R_CYTK10n subsystem: Nucleotides R_CYTK10n equation: [n] : cmp + dgtp <==> cdp + dgdp R_CYTK6n subsystem: Nucleotides R_CYTK6n equation: [n] : cmp + ctp <==> (2) cdp R_CYTK6 subsystem: Nucleotides R_CYTK6 equation: [c] : cmp + ctp <==> (2) cdp R_UMPK5 subsystem: Nucleotides R_UMPK5 equation: [c] : datp + ump <==> dadp + udp R_CYTK11 subsystem: Nucleotides R_CYTK11 equation: [c] : dcmp + dgtp <==> dcdp + dgdp R_UMPK3n subsystem: Nucleotides R_UMPK3n equation: [n] : ump + utp <==> (2) udp R_UMPK6n subsystem: Nucleotides R_UMPK6n equation: [n] : dctp + ump <==> dcdp + udp R_CYTK14n subsystem: Nucleotides R_CYTK14n equation: [n] : dcmp + utp <==> dcdp + udp R_UMPK2 subsystem: Nucleotides R_UMPK2 equation: [c] : ctp + ump <==> cdp + udp R_CYTK2n subsystem: Nucleotides R_CYTK2n equation: [n] : atp + dcmp <==> adp + dcdp R_UMPK6 subsystem: Nucleotides R_UMPK6 equation: [c] : dctp + ump <==> dcdp + udp R_UMPK4 subsystem: Nucleotides R_UMPK4 equation: [c] : gtp + ump <==> gdp + udp R_CYTK2 subsystem: Nucleotides R_CYTK2 equation: [c] : atp + dcmp <==> adp + dcdp R_UMPK5n subsystem: Nucleotides R_UMPK5n equation: [n] : datp + ump <==> dadp + udp R_UMPK subsystem: Nucleotides R_UMPK equation: [c] : atp + ump <==> adp + udp R_CYTK13 subsystem: Nucleotides R_CYTK13 equation: [c] : datp + dcmp <==> dadp + dcdp R_CYTK13n subsystem: Nucleotides R_CYTK13n equation: [n] : datp + dcmp <==> dadp + dcdp R_UMPK2n subsystem: Nucleotides R_UMPK2n equation: [n] : ctp + ump <==> cdp + udp R_CYTK9n subsystem: Nucleotides R_CYTK9n equation: [n] : cmp + dctp <==> cdp + dcdp R_CYTK7n subsystem: Nucleotides R_CYTK7n equation: [n] : cmp + utp <==> cdp + udp R_CYTK7 subsystem: Nucleotides R_CYTK7 equation: [c] : cmp + utp <==> cdp + udp R_CYTK3n subsystem: Nucleotides R_CYTK3n equation: [n] : ctp + dcmp <==> cdp + dcdp R_CYTK1 subsystem: Nucleotides R_CYTK1 equation: [c] : atp + cmp <==> adp + cdp R_CYTK14 subsystem: …
reactant: 976705
reactant: 976632
reactant: 976567
type: Reaction
is: ENSPTRG00000000712.3
product: 976814
is: http://identifiers.org/ec-code/2.7.4.14
product: 976802
reactant: 976606
product: 976838
product: 976826

955352
stoichiometry: 1.0
species: 897492
type: SpeciesReference

918735
stoichiometry: 6.0
species: 884427
type: SpeciesReference

977092
stoichiometry: 1.0
species: 898636
type: SpeciesReference

993995
stoichiometry: 1.0
species: 891676
type: SpeciesReference

962694
stoichiometry: 1.0
species: 877118
type: SpeciesReference

923302
stoichiometry: 1.0
species: 887314
type: SpeciesReference

982241
stoichiometry: 1.0
species: 904236
type: SpeciesReference

989630
stoichiometry: 1.0
species: 894212
type: SpeciesReference

919692
stoichiometry: 1.0
species: 896403
type: SpeciesReference

902066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

963030
stoichiometry: 8.0
species: 891616
type: SpeciesReference

990577
stoichiometry: 2.0
species: 896511
type: SpeciesReference

935349
stoichiometry: 3.0
species: 881499
type: SpeciesReference

921253
stoichiometry: 1.0
species: 880511
type: SpeciesReference

934245
stoichiometry: 1.0
species: 895012
type: SpeciesReference

975786
stoichiometry: 2.0
species: 891483
type: SpeciesReference

933406
stoichiometry: 1.0
species: 891483
type: SpeciesReference

949809
stoichiometry: 1.0
species: 899626
type: SpeciesReference

950810
stoichiometry: 1.0
species: 899033
type: SpeciesReference

887193
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dolichyl beta-D-glucosyl phosphate, human uterine homolog_C1085H1780O90P10
type: Species

944327
stoichiometry: 1.0
species: 892667
type: SpeciesReference

996085
stoichiometry: 1.0
species: 891591
type: SpeciesReference

932463
stoichiometry: 1.0
species: 891591
type: SpeciesReference

906547
product: 960123
reactant: 960087
product: 960111
type: Reaction
fast: false
reversible: false
notes: R_CORE2GTg subsystem: O-Glycan Biosynthesis R_CORE2GTg equation: [g] : T_antigen + uacgam --> core2 + h + udp
product: 960136
is: ENSPTRG00000016992.3
name: Core 2 acetylglucosaminyltransferase, Golgi apparatus
is: http://identifiers.org/ec-code/2.4.1.102
reactant: 960099

908133
stoichiometry: 2.0
species: 897261
type: SpeciesReference

980487
stoichiometry: 1.0
species: 891531
type: SpeciesReference

925536
stoichiometry: 4.0
species: 896245
type: SpeciesReference

939546
stoichiometry: 1.0
species: 886588
type: SpeciesReference

888998
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)3 (Glc)1 (GlcNAc)2 (LFuc)3 (Cer)1_C76H132N3O44FULLRCO
type: Species

884548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Cortisone_C21H28O5
type: Species

906307
reversible: false
notes: R_PTE2x subsystem: Fatty Acid Metabolism R_PTE2x equation: [x] : h2o + pmtcoa --> coa + h + hdca
type: Reaction
reactant: 958236
product: 958260
name: peroxisomal acyl-CoA thioesterase
is: ENSPTRG00000013567.4
fast: false
reactant: 958224
product: 958272
product: 958248

930955
stoichiometry: 1.0
species: 900148
type: SpeciesReference

988253
stoichiometry: 1.0
species: 899372
type: SpeciesReference

880280
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Aminoacetone_C3H8NO
type: Species

955955
stoichiometry: 1.0
species: 899530
type: SpeciesReference

986119
stoichiometry: 1.0
species: 877468
type: SpeciesReference

909945
type: Reaction
reversible: false
product: 991316
reactant: 991256
product: 991292
fast: false
is: http://identifiers.org/ec-code/2.4.99.4
reactant: 991244
product: 991304
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1
is: ENSPTRG00000004461.5
reactant: 991268
product: 991280

954011
stoichiometry: 1.0
species: 881945
type: SpeciesReference

999091
stoichiometry: 1.0
species: 890819
type: SpeciesReference

890422
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO
type: Species

975111
stoichiometry: 1.0
species: 900328
type: SpeciesReference

986058
stoichiometry: 3.0
species: 891640
type: SpeciesReference

947218
stoichiometry: 1.0
species: 888454
type: SpeciesReference

940187
stoichiometry: 5.0
species: 897407
type: SpeciesReference

877203
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _2-Decaprenyl-6-methoxy-1,4-benzoquinone_C57H86O3
type: Species

981868
stoichiometry: 1.0
species: 891591
type: SpeciesReference

980620
stoichiometry: 1.0
species: 898937
type: SpeciesReference

971431
stoichiometry: 23.0
species: 891640
type: SpeciesReference

952116
stoichiometry: 2.0
species: 891591
type: SpeciesReference

947363
stoichiometry: 1.0
species: 882139
type: SpeciesReference

971154
stoichiometry: 1.0
species: 882889
type: SpeciesReference

992207
stoichiometry: 1.0
species: 900436
type: SpeciesReference

990003
stoichiometry: 1.0
species: 894383
type: SpeciesReference

997172
stoichiometry: 1.0
species: 900897
type: SpeciesReference

926428
stoichiometry: 1.0
species: 899578
type: SpeciesReference

928432
stoichiometry: 1.0
species: 888828
type: SpeciesReference

892377
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 14_C57H84N3O62S5
type: Species

965378
stoichiometry: 1.0
species: 884754
type: SpeciesReference

910077
reactant: 992497
product: 992558
reversible: true
reactant: 992533
reactant: 992473
product: 992546
type: Reaction
reactant: 992521
fast: false
reactant: 992509
notes: R_H2Ot subsystem: Transport, Extracellular R_H2Ot equation: h2o[e] <==> h2o[c] R_UREAt5 subsystem: Transport, Extracellular R_UREAt5 equation: h2o[e] + urea[e] <==> h2o[c] + urea[c] R_GLCt4_2 subsystem: Transport, Extracellular R_GLCt4_2 equation: glc-D[e] + (2) na1[e] <==> glc-D[c] + (2) na1[c] R_GLCt2_2 subsystem: Transport, Extracellular R_GLCt2_2 equation: glc-D[e] + (2) h[e] <==> glc-D[c] + (2) h[c] R_UREAt subsystem: Transport, Extracellular R_UREAt equation: urea[e] <==> urea[c] R_GALt2_2 subsystem: Transport, Extracellular R_GALt2_2 equation: gal[e] + (2) h[e] <==> gal[c] + (2) h[c] R_GALt4_2 subsystem: Transport, Extracellular R_GALt4_2 equation: gal[e] + (2) na1[e] <==> gal[c] + (2) na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
product: 992583
is: ENSPTRG00000014282.2
product: 992571
is: ENSPTRG00000008861.4
product: 992608
reactant: 992485
product: 992595

935325
stoichiometry: 2.0
species: 891591
type: SpeciesReference

901911
product: 919558
product: 919595
reversible: true
product: 919582
is: ENSPTRG00000018506.4
fast: false
reactant: 919510
reactant: 919522
reactant: 919534
type: Reaction
reactant: 919546
notes: R_PHEtec subsystem: Transport, Extracellular R_PHEtec equation: phe-L[e] <==> phe-L[c] R_TYRt subsystem: Transport, Extracellular R_TYRt equation: tyr-L[e] <==> tyr-L[c] R_TRPt subsystem: Transport, Extracellular R_TRPt equation: trp-L[e] <==> trp-L[c] R_34DHPHEt subsystem: Transport, Extracellular R_34DHPHEt equation: _34dhphe[e] <==> 34dhphe[c]
product: 919570

903150
is: http://identifiers.org/ec-code/4.99.1.1
product: 929564
fast: false
is: ENSPTRG00000002245.5
reversible: false
notes: R_FCLTm subsystem: Heme Biosynthesis R_FCLTm equation: [m] : fe2 + ppp9 --> (2) h + pheme
reactant: 929540
reactant: 929552
type: Reaction
name: Ferrochelatase, mitochondrial
product: 929576

958621
stoichiometry: 1.0
species: 897443
type: SpeciesReference

969998
stoichiometry: 1.0
species: 877118
type: SpeciesReference

925392
stoichiometry: 1.0
species: 903536
type: SpeciesReference

956617
stoichiometry: 1.0
species: 895460
type: SpeciesReference

929372
stoichiometry: 1.0
species: 898503
type: SpeciesReference

949243
stoichiometry: 3.0
species: 888418
type: SpeciesReference

983434
stoichiometry: 1.0
species: 898792
type: SpeciesReference

922854
stoichiometry: 1.0
species: 894807
type: SpeciesReference

909417
product: 985233
product: 985294
reactant: 985173
product: 985245
type: Reaction
reactant: 985221
is: ENSPTRG00000005143.4
reactant: 985197
is: http://identifiers.org/ec-code/2.4.1.92
reactant: 985185
fast: false
reversible: false
product: 985257
reactant: 985209
notes: R_GALGT3 subsystem: Sphingolipid Metabolism R_GALGT3 equation: [g] : gd3_hs + udpacgal --> gd2_hs + h + udp R_GALGT2 subsystem: Sphingolipid Metabolism R_GALGT2 equation: [g] : gm3_hs + udpacgal --> gm2_hs + h + udp R_GALGT4 subsystem: Sphingolipid Metabolism R_GALGT4 equation: [g] : gt3_hs + udpacgal --> gt2_hs + h + udp R_GALGT1 subsystem: Sphingolipid Metabolism R_GALGT1 equation: [g] : galgluside_hs + udpacgal --> ga2_hs + h + udp
product: 985282
product: 985269

965161
stoichiometry: 1.0
species: 878289
type: SpeciesReference

890107
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Geranylgeranyl diphosphate_C20H33O7P2
type: Species

941480
stoichiometry: 2.0
species: 891664
type: SpeciesReference

973651
stoichiometry: 2.0
species: 891664
type: SpeciesReference

978301
stoichiometry: 1.0
species: 900556
type: SpeciesReference

979980
stoichiometry: 1.0
species: 886444
type: SpeciesReference

878180
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3-Sulfinopyruvate_C3H2O5S
type: Species

909942
stoichiometry: 1.0
species: 899045
type: SpeciesReference

001063
stoichiometry: 2.0
species: 882781
type: SpeciesReference

902067
product: 921059
product: 921035
product: 921047
name: heparin-glucosamine 3-O-sulfotransferase
reversible: false
reactant: 921023
is: ENSPTRG00000019557.4
fast: false
is: http://identifiers.org/ec-code/2.8.2.23
notes: R_S3T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T1g equation: [g] : hs_pre13 + paps --> h + hs_pre14 + pap
type: Reaction
reactant: 921011

998248
stoichiometry: 1.0
species: 901130
type: SpeciesReference

901910
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: stearidonyl coenzyme A_C39H58N7O17P3S
type: Species

960389
stoichiometry: 4.0
species: 891604
type: SpeciesReference

986591
stoichiometry: 1.0
species: 897516
type: SpeciesReference

957584
stoichiometry: 25.0
species: 891591
type: SpeciesReference

910498
product: 994249
type: Reaction
is: ENSPTRG00000034086.1
name: _13-cis-retinoic acid isomerase
reactant: 994237
fast: false
is: ENSPTRG00000001062.3
reversible: true
is: ENSPTRG00000001060.3
notes: R_RAI3 subsystem: Vitamin A Metabolism R_RAI3 equation: [c] : retn <==> 13-cis-retn
is: ENSPTRG00000001061.4

956040
stoichiometry: 1.0
species: 879078
type: SpeciesReference

887752
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-erythro-4-Hydroxyglutamate_C5H8NO5
type: Species

008159
stoichiometry: 1.0
species: 882139
type: SpeciesReference

978594
stoichiometry: 3.0
species: 891483
type: SpeciesReference

913169
stoichiometry: 2.0
species: 891591
type: SpeciesReference

953949
stoichiometry: 1.0
species: 899795
type: SpeciesReference

924570
stoichiometry: 1.0
species: 880183
type: SpeciesReference

966975
stoichiometry: 1.0
species: 893163
type: SpeciesReference

001111
stoichiometry: 2.0
species: 882090
type: SpeciesReference

000651
stoichiometry: 1.0
species: 879258
type: SpeciesReference

903004
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: timnodonyl coenzyme A_C41H60N7O17P3S
type: Species

961198
stoichiometry: 1.0
species: 891664
type: SpeciesReference

972166
stoichiometry: 1.0
species: 894879
type: SpeciesReference

931702
stoichiometry: 1.0
species: 879763
type: SpeciesReference

936303
stoichiometry: 1.0
species: 884995
type: SpeciesReference

917237
stoichiometry: 1.0
species: 892909
type: SpeciesReference

941324
stoichiometry: 1.0
species: 883155
type: SpeciesReference

949989
stoichiometry: 1.0
species: 895326
type: SpeciesReference

954677
stoichiometry: 1.0
species: 881427
type: SpeciesReference

919354
stoichiometry: 2.0
species: 897660
type: SpeciesReference

893719
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 2_C241H384N17O210S12
type: Species

917382
stoichiometry: 1.0
species: 897321
type: SpeciesReference

922637
stoichiometry: 1.0
species: 890313
type: SpeciesReference

916260
stoichiometry: 4.0
species: 891591
type: SpeciesReference

907714
product: 969329
product: 969280
reversible: false
notes: R_S4T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T1g equation: [g] : cs_pre + (2) paps --> cs_a,b,e_pre1 + (2) h + (2) pap R_S4T6g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T6g equation: [g] : cs_b_pre4 + paps --> cs_b_pre5 + h + pap R_S4T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T3g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5a + h + pap R_S4T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S4T2g equation: [g] : cs_a,b_pre3 + paps --> cspg_a + h + pap
is: ENSPTRG00000005379.2
type: Reaction
is: http://identifiers.org/ec-code/2.8.2.5
reactant: 969268
product: 969317
reactant: 969244
product: 969293
fast: false
product: 969305
reactant: 969256
is: ENSPTRG00000006922.4
is: ENSPTRG00000015335.3
is: ENSPTRG00000018861.4
product: 969341
reactant: 969232
reactant: 969220

911591
reversible: false
modifier: 006236
type: Reaction
modifier: 006248
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
modifier: 006309
product: 006200
is: http://identifiers.org/ec-code/1.2.3.5
modifier: 006260
reactant: 006164
modifier: 006224
modifier: 006321
is: ENSPTRG00000003425.5
modifier: 006272
modifier: 006284
reactant: 006176
is: http://identifiers.org/ec-code/1.1.1.27
fast: false
modifier: 006296
reactant: 006152
product: 006212
product: 006188

969160
stoichiometry: 1.0
species: 902896
type: SpeciesReference

883276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: cervonyl coenzyme A_C43H62N7O17P3S
type: Species

904248
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _25-Hydroxycholesterol_C27H46O2
type: Species

905625
stoichiometry: 1.0
species: 897528
type: SpeciesReference

908680
stoichiometry: 3.0
species: 884270
type: SpeciesReference

963650
stoichiometry: 30.0
species: 897261
type: SpeciesReference

898973
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Pantetheine 4'-phosphate_C11H21N2O7PS
type: Species

952672
stoichiometry: 2.0
species: 888346
type: SpeciesReference

898260
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S
type: Species

909633
notes: R_FMNAT subsystem: Riboflavin Metabolism R_FMNAT equation: [c] : atp + fmn + h --> fad + ppi
is: ENSPTRG00000001399.4
reversible: false
reactant: 987566
product: 987614
name: FMN adenylyltransferase
type: Reaction
fast: false
reactant: 987578
product: 987602
is: http://identifiers.org/ec-code/2.7.7.2
reactant: 987590

886215
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: debrisoquine_C10H14N3
type: Species

003932
stoichiometry: 1.0
species: 891736
type: SpeciesReference

006831
stoichiometry: 2.0
species: 891483
type: SpeciesReference

877902
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3-Methylbut-2-enoyl-CoA_C26H38N7O17P3S
type: Species

996666
stoichiometry: 1.0
species: 881885
type: SpeciesReference

947833
stoichiometry: 1.0
species: 894603
type: SpeciesReference

905166
stoichiometry: 1.0
species: 899287
type: SpeciesReference

003198
stoichiometry: 33.0
species: 880523
type: SpeciesReference

004125
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species: 893671
type: SpeciesReference

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species: 895138
type: SpeciesReference

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species: 880837
type: SpeciesReference

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boundary condition: false
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initial amount: NaN
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type: Species

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stoichiometry: 1.0
species: 897443
type: SpeciesReference

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stoichiometry: 1.0
species: 902932
type: SpeciesReference

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stoichiometry: 1.0
species: 890856
type: SpeciesReference

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stoichiometry: 1.0
species: 897395
type: SpeciesReference

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stoichiometry: 1.0
species: 880051
type: SpeciesReference

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stoichiometry: 32.0
species: 897431
type: SpeciesReference

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stoichiometry: 1.0
species: 896088
type: SpeciesReference

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stoichiometry: 6.0
species: 891748
type: SpeciesReference

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stoichiometry: 1.0
species: 893756
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
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type: Species

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stoichiometry: 2.0
species: 891664
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Dehydroepiandrosterone sulfate_C19H27O5S
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: GMP_C10H12N5O8P
type: Species

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stoichiometry: 1.0
species: 879210
type: SpeciesReference

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stoichiometry: 1.0
species: 881897
type: SpeciesReference

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stoichiometry: 1.0
species: 900388
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3
type: Species

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stoichiometry: 3.0
species: 879090
type: SpeciesReference

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product: 938921
reversible: false
is: ENSPTRG00000013426.3
fast: false
type: Reaction
product: 938897
product: 938909
reactant: 938885
reactant: 938861
is: http://identifiers.org/ec-code/6.3.2.3
product: 938933
reactant: 938873
name: glutathione synthetase
notes: R_GTHS subsystem: Glutathione Metabolism R_GTHS equation: [c] : atp + glucys + gly --> adp + gthrd + h + pi

950689
stoichiometry: 8.0
species: 887437
type: SpeciesReference

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stoichiometry: 2.0
species: 891591
type: SpeciesReference

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stoichiometry: 16.0
species: 890167
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Ascorbate_C6H8O6
type: Species

906762
stoichiometry: 1.0
species: 897516
type: SpeciesReference

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stoichiometry: 1.0
species: 894566
type: SpeciesReference

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product: 911246
reactant: 911174
fast: false
reactant: 911198
reversible: false
product: 911258
type: Reaction
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap
reactant: 911162
reactant: 911186
product: 911210
is: ENSPTRG00000003535.4
product: 911234
product: 911222

992909
stoichiometry: 4.0
species: 891555
type: SpeciesReference

966539
stoichiometry: 1.0
species: 881258
type: SpeciesReference

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stoichiometry: 2.0
species: 885997
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Leb glycolipid_C56H99N2O30FULLRCO
type: Species

899482
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phytanic acid_C20H39O2
type: Species

949965
stoichiometry: 1.0
species: 891917
type: SpeciesReference

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stoichiometry: 1.0
species: 883711
type: SpeciesReference

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stoichiometry: 1.0
species: 888019
type: SpeciesReference

987951
stoichiometry: 2.0
species: 899819
type: SpeciesReference

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stoichiometry: 1.0
species: 879162
type: SpeciesReference

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stoichiometry: 1.0
species: 904224
type: SpeciesReference

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stoichiometry: 1.0
species: 900605
type: SpeciesReference

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stoichiometry: 1.0
species: 884319
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: acyl carrier protein_C11H21N2O7PRS
type: Species

942546
stoichiometry: 1.0
species: 878096
type: SpeciesReference

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stoichiometry: 1.0
species: 894807
type: SpeciesReference

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stoichiometry: 1.0
species: 895737
type: SpeciesReference

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stoichiometry: 1.0
species: 894627
type: SpeciesReference

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stoichiometry: 1.0
species: 891640
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: alpha-linolenyl carnitine_C25H43NO4
type: Species

905055
stoichiometry: 1.0
species: 890131
type: SpeciesReference

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stoichiometry: 1.0
species: 895907
type: SpeciesReference

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stoichiometry: 1.0
species: 882529
type: SpeciesReference

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stoichiometry: 1.0
species: 888188
type: SpeciesReference

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stoichiometry: 1.0
species: 886648
type: SpeciesReference

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product: 961571
product: 961583
is: http://identifiers.org/ec-code/1.14.19.1
fast: false
reactant: 961510
reactant: 961522
type: Reaction
reactant: 961559
product: 961595
notes: R_DESAT20_1 subsystem: Fatty acid elongation R_DESAT20_1 equation: [c] : dlnlcgcoa + h + nadh + o2 --> arachdcoa + (2) h2o + nad R_DESAT20_2 subsystem: Fatty acid elongation R_DESAT20_2 equation: [c] : eicostetcoa + h + nadh + o2 --> (2) h2o + nad + tmndnccoa
is: ENSPTRG00000003754.5
reactant: 961535
product: 961607
reactant: 961547
reversible: false

918893
stoichiometry: 1.0
species: 880486
type: SpeciesReference

908898
stoichiometry: 3.0
species: 897407
type: SpeciesReference

997619
stoichiometry: 1.0
species: 885744
type: SpeciesReference

005044
stoichiometry: 2.0
species: 888261
type: SpeciesReference

010007
stoichiometry: 1.0
species: 880401
type: SpeciesReference

957246
stoichiometry: 1.0
species: 883988
type: SpeciesReference

891290
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Reduced glutathione_C10H16N3O6S
type: Species

928974
stoichiometry: 1.0
species: 897261
type: SpeciesReference

901126
reversible: false
product: 914269
reactant: 914245
product: 914281
is: ENSPTRG00000015590.4
is: http://identifiers.org/ec-code/3.2.1.10
product: 914257
product: 914294
type: Reaction
notes: R_O16G1e subsystem: Starch and Sucrose Metabolism R_O16G1e equation: [e] : glygn4 + h2o --> glc-D + glygn5 R_SUCRe subsystem: Galactose metabolism R_SUCRe equation: [e] : h2o + sucr --> fru + glc-D R_O16G2e subsystem: Starch and Sucrose Metabolism R_O16G2e equation: [e] : h2o + strch2 --> glc-D + malt
reactant: 914233
is: http://identifiers.org/ec-code/3.2.1.26
reactant: 914221
fast: false
reactant: 914209

004666
stoichiometry: 1.0
species: 890686
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Propanoyl-CoA_C24H36N7O17P3S
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

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stoichiometry: 1.0
species: 901765
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: S-Adenosylmethioninamine_C14H24N6O3S
type: Species

943926
stoichiometry: 1.0
species: 892159
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 4_C101H165N7O72X
type: Species

994998
stoichiometry: 1.0
species: 891483
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _5alpha-Cholest-7-en-3beta-ol_C27H46O
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Acetyl-D-mannosamine 6-phosphate_C8H14NO9P
type: Species

904982
stoichiometry: 1.0
species: 897225
type: SpeciesReference

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stoichiometry: 5.0
species: 891519
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 7_C67H99N4O80S8
type: Species

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stoichiometry: 3.0
species: 890326
type: SpeciesReference

932042
stoichiometry: 1.0
species: 888659
type: SpeciesReference

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stoichiometry: 1.0
species: 878000
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: D-Glucose 6-phosphate_C6H11O9P
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Triiodothyronine sulfate_C15H11I3NO7S
type: Species

958513
stoichiometry: 1.0
species: 897007
type: SpeciesReference

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stoichiometry: 1.0
species: 883567
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: nLc8Cer_C72H125N4O42FULLRCO
type: Species

960956
stoichiometry: 1.0
species: 890155
type: SpeciesReference

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stoichiometry: 2.0
species: 884451
type: SpeciesReference

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stoichiometry: 4.0
species: 901549
type: SpeciesReference

998826
stoichiometry: 1.0
species: 894140
type: SpeciesReference

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stoichiometry: 1.0
species: 904200
type: SpeciesReference

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stoichiometry: 1.0
species: 889070
type: SpeciesReference

902607
reactant: 925380
reactant: 925368
product: 925404
product: 925392
is: ENSPTRG00000021261.3
notes: R_UGCG subsystem: Sphingolipid Metabolism R_UGCG equation: [r] : crm_hs + udpg --> gluside_hs + h + udp
is: http://identifiers.org/ec-code/2.4.1.80
product: 925416
type: Reaction
reversible: false
fast: false
name: Ceramide glucosyltransferase

971707
stoichiometry: 1.0
species: 898092
type: SpeciesReference

963360
stoichiometry: 1.0
species: 897588
type: SpeciesReference

897648
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Ammonium_H4N
type: Species

885816
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dATP_C10H12N5O12P3
type: Species

933625
stoichiometry: 1.0
species: 887278
type: SpeciesReference

944545
stoichiometry: 2.0
species: 895944
type: SpeciesReference

884766
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Corticosterone_C21H30O4
type: Species

917634
stoichiometry: 2.0
species: 897516
type: SpeciesReference

959484
stoichiometry: 1.0
species: 899807
type: SpeciesReference

992753
stoichiometry: 1.0
species: 882493
type: SpeciesReference

882334
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Apocarboxylase (Lys residue)_C6H13N2OX
type: Species

908684
product: 980246
name: Phosphoenolpyruvate carboxykinase (GTP)
product: 980234
product: 980222
notes: R_PEPCKm subsystem: Glycolysis/Gluconeogenesis R_PEPCKm equation: [m] : gtp + oaa --> co2 + gdp + pep
is: http://identifiers.org/ec-code/4.1.1.32
reactant: 980210
fast: false
is: ENSPTRG00000006191.2
type: Reaction
reactant: 980198
reversible: false

942388
stoichiometry: 35.0
species: 891567
type: SpeciesReference

952333
stoichiometry: 4.0
species: 897321
type: SpeciesReference

008851
stoichiometry: 1.0
species: 897321
type: SpeciesReference

960221
stoichiometry: 1.0
species: 884463
type: SpeciesReference

989268
stoichiometry: 1.0
species: 890155
type: SpeciesReference

003077
stoichiometry: 23.0
species: 891471
type: SpeciesReference

996230
stoichiometry: 1.0
species: 888370
type: SpeciesReference

987218
stoichiometry: 2.0
species: 899530
type: SpeciesReference

902608
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al_C27H46O4
type: Species

900776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Ubiquinol-10_C59H92O4
type: Species

910798
name: hydroxyacylglutathione hydrolase
is: ENSPTRG00000007560.4
product: 996798
reactant: 996762
product: 996786
is: http://identifiers.org/ec-code/3.1.2.6
notes: R_GLYOX subsystem: Pyruvate Metabolism R_GLYOX equation: [c] : h2o + lgt-S --> gthrd + h + lac-D
reactant: 996774
reversible: false
type: Reaction
product: 996810
fast: false

932681
stoichiometry: 2.0
species: 885744
type: SpeciesReference

877420
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3,4-Dihydroxy-trans-cinnamate_C9H7O4
type: Species

005718
stoichiometry: 1.0
species: 897347
type: SpeciesReference

879354
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _6-phospho-D-glucono-1,5-lactone_C6H9O9P
type: Species

966757
stoichiometry: 1.0
species: 901245
type: SpeciesReference

964886
stoichiometry: 1.0
species: 903378
type: SpeciesReference

957439
stoichiometry: 1.0
species: 890131
type: SpeciesReference

945290
stoichiometry: 2.0
species: 891531
type: SpeciesReference

908138
type: Reaction
is: ENSPTRG00000000398.3
notes: R_NAt5 subsystem: Transport, Extracellular R_NAt5 equation: na1[c] + nh4[e] <==> na1[e] + nh4[c] R_NAt3_1 subsystem: Transport, Extracellular R_NAt3_1 equation: h[e] + na1[c] <==> h[c] + na1[e]
fast: false
is: ENSPTRG00000016682.3
is: ENSPTRG00000012305.2
reactant: 974954
reactant: 974942
product: 975002
product: 974990
reactant: 974966
product: 974978
reversible: true

008597
stoichiometry: 2.0
species: 891519
type: SpeciesReference

988470
stoichiometry: 1.0
species: 890155
type: SpeciesReference

943752
stoichiometry: 1.0
species: 889250
type: SpeciesReference

937689
stoichiometry: 1.0
species: 904657
type: SpeciesReference

005192
stoichiometry: 1.0
species: 902872
type: SpeciesReference

996883
stoichiometry: 1.0
species: 887241
type: SpeciesReference

983651
stoichiometry: 1.0
species: 878619
type: SpeciesReference

928216
stoichiometry: 2.0
species: 890155
type: SpeciesReference

885707
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dADP_C10H12N5O9P2
type: Species

006541
stoichiometry: 5.0
species: 899530
type: SpeciesReference

888563
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide_C8H13N2O9P
type: Species

896403
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Mannose_C6H12O6
type: Species

958729
stoichiometry: 2.0
species: 898116
type: SpeciesReference

884850
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 1_C45H68N2O43S2
type: Species

905620
product: 951875
name: acylphosphatase
product: 951851
fast: false
is: ENSPTRG00000018380.2
is: ENSPTRG00000006549.3
notes: R_ACYP subsystem: Glycolysis/Gluconeogenesis R_ACYP equation: [c] : 13dpg + h2o --> 3pg + h + pi
reactant: 951827
product: 951863
is: http://identifiers.org/ec-code/3.6.1.7
reactant: 951839
type: Reaction
reversible: false
is: ENSPTRG00000011921.3

902487
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: tetracosatetraenoic acid n-6_C24H39O2
type: Species

979425
stoichiometry: 2.0
species: 899602
type: SpeciesReference

971864
stoichiometry: 1.0
species: 894236
type: SpeciesReference

980138
stoichiometry: 1.0
species: 896209
type: SpeciesReference

929528
stoichiometry: 1.0
species: 899311
type: SpeciesReference

943029
stoichiometry: 2.0
species: 891254
type: SpeciesReference

986699
stoichiometry: 4.0
species: 891591
type: SpeciesReference

985914
stoichiometry: 1.0
species: 886552
type: SpeciesReference

901597
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Sulfate_O4S
type: Species

914631
stoichiometry: 1.0
species: 889972
type: SpeciesReference

886093
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Deoxycytidine_C9H13N3O4
type: Species

954387
stoichiometry: 1.0
species: 893574
type: SpeciesReference

977506
stoichiometry: 1.0
species: 892729
type: SpeciesReference

986277
stoichiometry: 2.0
species: 898696
type: SpeciesReference

967834
stoichiometry: 1.0
species: 883807
type: SpeciesReference

996122
stoichiometry: 1.0
species: 883940
type: SpeciesReference

968654
stoichiometry: 1.0
species: 882601
type: SpeciesReference

949557
stoichiometry: 1.0
species: 891591
type: SpeciesReference

975486
stoichiometry: 1.0
species: 878433
type: SpeciesReference

909093
product: 982926
reactant: 982866
is: http://identifiers.org/ec-code/3.6.3.10
is: ENSPTRG00000006063.2
reactant: 982890
fast: false
reversible: false
name: H+/K+ gastric/non-gastric P-ATPase and ABC ATPase
is: ENSPTRG00000010850.3
reactant: 982878
type: Reaction
product: 982914
product: 982938
product: 982902
notes: R_HKt subsystem: Transport, Extracellular R_HKt equation: atp[c] + h2o[c] + k[e] --> adp[c] + h[e] + k[c] + pi[c]

007241
stoichiometry: 1.0
species: 895278
type: SpeciesReference

010332
stoichiometry: 2.0
species: 891591
type: SpeciesReference

904526
product: 941058
reactant: 941046
notes: R_H2Otm subsystem: Transport, Mitochondrial R_H2Otm equation: h2o[c] <==> h2o[m]
is: ENSPTRG00000007905.2
fast: false
reversible: true
name: H2O transport, mitochondrial
type: Reaction

970649
stoichiometry: 1.0
species: 880317
type: SpeciesReference

008743
stoichiometry: 4.0
species: 884319
type: SpeciesReference

952443
stoichiometry: 1.0
species: 887229
type: SpeciesReference

908792
reactant: 980901
modifier: 980986
modifier: 981035
modifier: 981022
modifier: 981010
modifier: 981107
modifier: 980998
notes: R_C2M26DCOAHLm subsystem: Limonene and pinene degradation R_C2M26DCOAHLm equation: [m] : c2m26dcoa + h2o <==> 3h26dm5coa R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad R_T2M26DCOAHLm subsystem: Limonene and pinene degradation R_T2M26DCOAHLm equation: [m] : h2o + t2m26dcoa <==> 3h26dm5coa R_ECOAH12m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH12m equation: [m] : 2mp2coa + h2o <==> 3hibutcoa R_PRPNCOAHYDm subsystem: beta-Alanine metabolism R_PRPNCOAHYDm equation: [m] : h2o + prpncoa --> 3hpcoa R_ECOAH9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH9m equation: [m] : 2mb2coa + h2o <==> 3hmbcoa R_ECOAH1m subsystem: Tryptophan metabolism R_ECOAH1m equation: [m] : 3hbcoa <==> b2coa + h2o R_ACACT1rm subsystem: Tryptophan metabolism R_ACACT1rm equation: [m] : (2) accoa <==> aacoa + coa
modifier: 981071
modifier: 980950
is: ENSPTRG00000008842.3
type: Reaction
modifier: 980926
is: http://identifiers.org/ec-code/4.2.1.17
modifier: 981095
modifier: 981083
modifier: 980938
product: 980913
modifier: 981059
modifier: 981047
modifier: 980962
reactant: 980889
reversible: false
is: http://identifiers.org/ec-code/2.3.1.9
is: ENSPTRG00000011733.4
modifier: 980974
is: http://identifiers.org/ec-code/1.1.1.35
fast: false

935071
stoichiometry: 1.0
species: 893199
type: SpeciesReference

899775
is: ENSPTRG00000021201.4
reversible: true
reactant: 904705
is: http://identifiers.org/ec-code/4.1.2.13
reactant: 904729
type: Reaction
reactant: 904717
product: 904753
product: 904777
reactant: 904693
product: 904765
notes: R_FBA4 subsystem: Glyoxylate and Dicarboxylate Metabolism R_FBA4 equation: [c] : xu1p-D <==> dhap + gcald R_FBA2 subsystem: Fructose and Mannose Metabolism R_FBA2 equation: [c] : f1p <==> dhap + glyald R_FBA5 subsystem: Galactose metabolism R_FBA5 equation: [c] : tag1p-D <==> dhap + glyald R_FBA subsystem: Glycolysis/Gluconeogenesis R_FBA equation: [c] : fdp <==> dhap + g3p
product: 904741
fast: false

921132
stoichiometry: 1.0
species: 897347
type: SpeciesReference

877311
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

989377
stoichiometry: 6.0
species: 897443
type: SpeciesReference

933733
stoichiometry: 1.0
species: 901681
type: SpeciesReference

958405
stoichiometry: 1.0
species: 897888
type: SpeciesReference

969124
stoichiometry: 1.0
species: 886093
type: SpeciesReference

912239
stoichiometry: 6.0
species: 885780
type: SpeciesReference

937533
stoichiometry: 1.0
species: 901233
type: SpeciesReference

988132
stoichiometry: 3.0
species: 899530
type: SpeciesReference

909094
stoichiometry: 1.0
species: 888309
type: SpeciesReference

942279
stoichiometry: 1.0
species: 885502
type: SpeciesReference

992644
stoichiometry: 1.0
species: 891604
type: SpeciesReference

894248
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 2_C87H142N6O62X
type: Species

911006
stoichiometry: 2.0
species: 882781
type: SpeciesReference

885925
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: chenodeoxycholoyl coenzyme a_C45H70N7O19P3S
type: Species

895605
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: gamma-linolenoyl-CoA_C39H60N7O17P3S
type: Species

981723
stoichiometry: 4.0
species: 891471
type: SpeciesReference

884657
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: ceramide (homo sapiens)_C18H36NO2FULLRCO
type: Species

886372
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Deoxyguanosine_C10H13N5O4
type: Species

939437
stoichiometry: 2.0
species: 891640
type: SpeciesReference

948736
stoichiometry: 1.0
species: 889526
type: SpeciesReference

963939
stoichiometry: 1.0
species: 898164
type: SpeciesReference

888672
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Formate_CH1O2
type: Species

947941
stoichiometry: 3.0
species: 888430
type: SpeciesReference

935625
stoichiometry: 1.0
species: 896740
type: SpeciesReference

902378
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S
type: Species

005453
stoichiometry: 1.0
species: 888188
type: SpeciesReference

983760
stoichiometry: 4.0
species: 897443
type: SpeciesReference

996774
stoichiometry: 1.0
species: 891483
type: SpeciesReference

900836
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: alpha-D-Ribose 5-phosphate_C5H9O8P
type: Species

927380
stoichiometry: 1.0
species: 900256
type: SpeciesReference

999916
stoichiometry: 1.0
species: 890264
type: SpeciesReference

939115
stoichiometry: 4.0
species: 891760
type: SpeciesReference

972807
stoichiometry: 1.0
species: 893538
type: SpeciesReference

000074
stoichiometry: 1.0
species: 882601
type: SpeciesReference

943643
stoichiometry: 1.0
species: 903209
type: SpeciesReference

966866
stoichiometry: 1.0
species: 890326
type: SpeciesReference

888840
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: V3Fuc-nLc6Cer_C64H112N3O36FULLRCO
type: Species

009405
stoichiometry: 3.0
species: 901426
type: SpeciesReference

005827
stoichiometry: 2.0
species: 891640
type: SpeciesReference

881595
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8
type: Species

010441
stoichiometry: 1.0
species: 900148
type: SpeciesReference

933831
stoichiometry: 1.0
species: 895012
type: SpeciesReference

935770
stoichiometry: 1.0
species: 897104
type: SpeciesReference

977615
stoichiometry: 1.0
species: 892753
type: SpeciesReference

896559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Metanephrine_C10H16NO3
type: Species

897225
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N4-Acetylaminobutanal_C6H11NO2
type: Species

902379
name: phospholipase A2
type: Reaction
product: 923847
product: 923871
reactant: 923823
reversible: false
fast: false
is: ENSPTRG00000014362.5
is: http://identifiers.org/ec-code/3.1.1.4
product: 923859
notes: R_PLA2_2 subsystem: Glycerophospholipid Metabolism R_PLA2_2 equation: [c] : h2o + pchol_hs --> Rtotal2 + h + lpchol_hs
reactant: 923835

877625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: _3'-AMP_C10H12N5O7P
type: Species

900544
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S
type: Species

928106
stoichiometry: 1.0
species: 894963
type: SpeciesReference

966118
stoichiometry: 1.96
species: 891531
type: SpeciesReference

914522
stoichiometry: 1.0
species: 892159
type: SpeciesReference

924824
stoichiometry: 1.0
species: 891616
type: SpeciesReference

900835
reversible: true
product: 911577
fast: false
is: ENSPTRG00000000109.3
is: ENSPTRG00000000217.5
product: 911589
notes: R_ENO subsystem: Glycolysis/Gluconeogenesis R_ENO equation: [c] : 2pg <==> h2o + pep
is: ENSPTRG00000008617.3
type: Reaction
reactant: 911565
is: http://identifiers.org/ec-code/4.2.1.11
name: enolase
is: ENSPTRG00000034081.1

955762
stoichiometry: 1.0
species: 890626
type: SpeciesReference

976862
stoichiometry: 3.0
species: 881258
type: SpeciesReference

997004
stoichiometry: 1.0
species: 883856
type: SpeciesReference

001269
stoichiometry: 1.0
species: 901789
type: SpeciesReference

008487
stoichiometry: 2.0
species: 897321
type: SpeciesReference

891062
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Geranyl diphosphate_C10H17O7P2
type: Species

985790
stoichiometry: 1.0
species: 884693
type: SpeciesReference

929637
stoichiometry: 2.0
species: 898080
type: SpeciesReference

993465
stoichiometry: 1.0
species: 885635
type: SpeciesReference

931076
stoichiometry: 1.0
species: 901838
type: SpeciesReference

994842
stoichiometry: 1.0
species: 891591
type: SpeciesReference

984062
stoichiometry: 5.0
species: 891628
type: SpeciesReference

887739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-erythro-4-Hydroxyglutamate_C5H8NO5
type: Species

010666
stoichiometry: 2.0
species: 891483
type: SpeciesReference

009983
stoichiometry: 1.0
species: 880389
type: SpeciesReference

979534
stoichiometry: 1.0
species: 898792
type: SpeciesReference

919245
stoichiometry: 1.0
species: 881523
type: SpeciesReference

004233
stoichiometry: 2.0
species: 885260
type: SpeciesReference

922746
stoichiometry: 1.0
species: 894116
type: SpeciesReference

896124
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X
type: Species

999782
stoichiometry: 1.0
species: 877408
type: SpeciesReference

998549
stoichiometry: 1.0
species: 894831
type: SpeciesReference

923751
stoichiometry: 1.0
species: 891495
type: SpeciesReference

936412
stoichiometry: 1.0
species: 890386
type: SpeciesReference

996558
stoichiometry: 1.0
species: 891543
type: SpeciesReference

998694
stoichiometry: 1.0
species: 894297
type: SpeciesReference

934397
stoichiometry: 1.0
species: 899021
type: SpeciesReference

895472
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: linoleic acid (all cis C18:2) n-6_C18H31O2
type: Species

898152
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Superoxide anion_O2
type: Species

928757
stoichiometry: 1.0
species: 901970
type: SpeciesReference

968172
stoichiometry: 1.0
species: 904404
type: SpeciesReference

952564
stoichiometry: 1.0
species: 882090
type: SpeciesReference

991268
stoichiometry: 1.0
species: 884488
type: SpeciesReference

995191
stoichiometry: 1.0
species: 882445
type: SpeciesReference

991400
stoichiometry: 1.0
species: 902258
type: SpeciesReference

887302
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Dolichol phosphate, human uterine homolog_C1025H1670O40P10
type: Species

898044
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: O2_O2
type: Species

889947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GD2 (homo sapiens)_C60H101N4O33FULLRCO
type: Species

879787
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Protein N6,N6,N6-trimethyl-L-lysine_C3H10X
type: Species

900546
reactant: 909760
reactant: 909797
is: ENSPTRG00000011025.4
product: 909845
is: ENSPTRG00000018372.4
type: Reaction
product: 909857
is: ENSPTRG00000001003.3
reactant: 909785
reactant: 909773
reactant: 909809
product: 909821
notes: R_OIVD2m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD2m equation: [m] : 3mob + coa + nad --> co2 + ibcoa + nadh R_OIVD3m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD3m equation: [m] : 3mop + coa + nad --> 2mbcoa + co2 + nadh R_OIVD1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_OIVD1m equation: [m] : 4mop + coa + nad --> co2 + ivcoa + nadh
fast: false
product: 909833
reversible: false
product: 909869
is: http://identifiers.org/ec-code/1.2.1.25

906870
stoichiometry: 2.0
species: 897552
type: SpeciesReference

949144
stoichiometry: 1.0
species: 894322
type: SpeciesReference

898478
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: hydroxide ion_HO
type: Species

911195
product: 000518
reactant: 000302
reactant: 000434
fast: false
reactant: 000422
product: 000578
reactant: 000506
reactant: 000470
product: 000530
reactant: 000494
type: Reaction
reactant: 000482
product: 000796
product: 000747
product: 000699
reactant: 000410
is: ENSPTRG00000017007.3
product: 000759
product: 000603
reactant: 000398
product: 000723
reversible: false
product: 000663
product: 000675
is: http://identifiers.org/ec-code/6.3.2.17
product: 000542
product: 000591
product: 000554
reactant: 000326
reactant: 000458
reactant: 000314
reactant: 000253
reactant: 000446
reactant: 000338
reactant: 000290
product: 000615
reactant: 000362
reactant: 000386
product: 000651
reactant: 000350
product: 000735
reactant: 000374
product: 000687
reactant: 000278
product: 000771
notes: R_FPGS subsystem: Folate Metabolism R_FPGS equation: [c] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS9 subsystem: Folate Metabolism R_FPGS9 equation: [c] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS3m subsystem: Folate Metabolism R_FPGS3m equation: [m] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS7 subsystem: Folate Metabolism R_FPGS7 equation: [c] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGSm subsystem: Folate Metabolism R_FPGSm equation: [m] : (4) atp + (4) glu-L + thf --> 5thf + (4) adp + (4) h + (4) pi R_FPGS4 subsystem: Folate Metabolism R_FPGS4 equation: [c] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS4m subsystem: Folate Metabolism R_FPGS4m equation: [m] : (4) atp + dhf + (4) glu-L --> 5dhf + (4) adp + (4) h + (4) pi R_FPGS6 subsystem: Folate Metabolism R_FPGS6 equation: [c] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS3 subsystem: Folate Metabolism R_FPGS3 equation: [c] : 6thf + atp + glu-L --> 7thf + adp + h + pi R_FPGS5m subsystem: Folate Metabolism R_FPGS5m equation: [m] : 5dhf + atp + glu-L --> 6dhf + adp + h + pi R_FPGS2m subsystem: Folate Metabolism R_FPGS2m equation: [m] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS8 subsystem: Folate Metabolism R_FPGS8 equation: [c] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS2 subsystem: Folate Metabolism R_FPGS2 equation: [c] : 5thf + atp + glu-L --> 6thf + adp + h + pi R_FPGS7m subsystem: Folate Metabolism R_FPGS7m equation: [m] : 10fthf + (4) atp + (4) glu-L --> 10fthf5glu + (4) adp + (4) h + (4) pi R_FPGS6m subsystem: Folate Metabolism R_FPGS6m equation: [m] : 6dhf + atp + glu-L --> 7dhf + adp + h + pi R_FPGS9m subsystem: Folate Metabolism R_FPGS9m equation: [m] : 10fthf6glu + atp + glu-L --> 10fthf7glu + adp + h + pi R_FPGS8m subsystem: Folate Metabolism R_FPGS8m equation: [m] : 10fthf5glu + atp + glu-L --> 10fthf6glu + adp + h + pi R_FPGS5 subsystem: Folate Metabolism R…
reactant: 000266
product: 000627
product: 000639
product: 000566
product: 000784
product: 000711

995598
stoichiometry: 1.0
species: 882853
type: SpeciesReference

908028
reactant: 973579
notes: R_DOLPMT3_Uer subsystem: N-Glycan Biosynthesis R_DOLPMT3_Uer equation: [r] : (0.1) dolmanp_U + (0.1) m6mpdol_U --> (0.1) dolp_U + h + (0.1) m7mpdol_U R_DOLPMT3_Ler subsystem: N-Glycan Biosynthesis R_DOLPMT3_Ler equation: [r] : (0.1) dolmanp_L + (0.1) m6mpdol_L --> (0.1) dolp_L + h + (0.1) m7mpdol_L
type: Reaction
reactant: 973567
is: ENSPTRG00000014523.4
is: http://identifiers.org/ec-code/2.4.1.130
fast: false
reversible: false
product: 973651
product: 973603
reactant: 973591
product: 973615
reactant: 973555
product: 973627
product: 973639

002218
stoichiometry: 1.0
species: 883579
type: SpeciesReference

939703
stoichiometry: 1.0
species: 897516
type: SpeciesReference

898864
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2
type: Species

948880
stoichiometry: 1.0
species: 894627
type: SpeciesReference

959230
stoichiometry: 1.0
species: 890131
type: SpeciesReference

911002
reactant: 998309
product: 998790
reactant: 998381
reactant: 998357
reactant: 998393
reactant: 998369
product: 998682
product: 998658
is: ENSPTRG00000013609.3
reactant: 998441
reactant: 998453
product: 998754
type: Reaction
reactant: 998465
product: 998585
reactant: 998477
product: 998802
reactant: 998405
notes: R_G14Tg subsystem: N-Glycan Biosynthesis R_G14Tg equation: [g] : fn2m2masn + (2) udpgal --> (2) h + l2fn2m2masn + (2) udp R_G14T7g subsystem: Keratan sulfate biosynthesis R_G14T7g equation: [g] : ksi_pre5 + udpgal --> h + ksi_pre6 + udp R_G14T21g subsystem: Keratan sulfate biosynthesis R_G14T21g equation: [g] : ksii_core4_pre9 + udpgal --> h + ksii_core4_pre10 + udp R_G14T13g subsystem: Keratan sulfate biosynthesis R_G14T13g equation: [g] : ksi_pre23 + udpgal --> h + ksi_pre24 + udp R_G14T17g subsystem: Keratan sulfate biosynthesis R_G14T17g equation: [g] : ksi_pre35 + udpgal --> h + ksi_pre36 + udp R_G14T20g subsystem: Keratan sulfate biosynthesis R_G14T20g equation: [g] : ksii_core4_pre6 + udpgal --> h + ksii_core4_pre7 + udp R_G14T16g subsystem: Keratan sulfate biosynthesis R_G14T16g equation: [g] : ksi_pre32 + udpgal --> h + ksi_pre33 + udp R_G14T3g subsystem: Keratan sulfate biosynthesis R_G14T3g equation: [g] : ksii_core2_pre3 + udpgal --> h + ksii_core2_pre4 + udp R_G14T10g subsystem: Keratan sulfate biosynthesis R_G14T10g equation: [g] : ksi_pre14 + udpgal --> h + ksi_pre15 + udp R_G14T12g subsystem: Keratan sulfate biosynthesis R_G14T12g equation: [g] : ksi_pre20 + udpgal --> h + ksi_pre21 + udp R_G14T15g subsystem: Keratan sulfate biosynthesis R_G14T15g equation: [g] : ksi_pre29 + udpgal --> h + ksi_pre30 + udp R_G14T9g subsystem: Keratan sulfate biosynthesis R_G14T9g equation: [g] : ksi_pre11 + udpgal --> h + ksi_pre12 + udp R_G14T2g subsystem: Keratan sulfate biosynthesis R_G14T2g equation: [g] : ksii_core2_pre1 + udpgal --> h + ksii_core2_pre2 + udp R_G14T6g subsystem: Keratan sulfate biosynthesis R_G14T6g equation: [g] : ksi_pre2 + udpgal --> h + ksi_pre3 + udp R_G14T19g subsystem: Keratan sulfate biosynthesis R_G14T19g equation: [g] : ksii_core4_pre3 + udpgal --> h + ksii_core4_pre4 + udp R_G14T4g subsystem: Keratan sulfate biosynthesis R_G14T4g equation: [g] : ksii_core2_pre6 + udpgal --> h + ksii_core2_pre7 + udp R_G14T8g subsystem: Keratan sulfate …
is: http://identifiers.org/ec-code/2.4.1.38
reactant: 998417
product: 998634
reactant: 998429
reactant: 998297
product: 998742
product: 998670
reactant: 998501
product: 998646
reactant: 998513
reactant: 998489
reactant: 998525
product: 998718
reversible: false
reactant: 998321
product: 998573
reactant: 998333
product: 998694
fast: false
reactant: 998345
product: 998597
is: ENSPTRG00000001575.4
product: 998826
product: 998622
product: 998766
product: 998730
product: 998706
reactant: 998537
product: 998609
product: 998814
product: 998561
product: 998778
reactant: 998549

905914
stoichiometry: 1.0
species: 886251
type: SpeciesReference

964508
stoichiometry: 1.0
species: 888273
type: SpeciesReference

976296
stoichiometry: 1.0
species: 887107
type: SpeciesReference

923194
stoichiometry: 1.0
species: 885611
type: SpeciesReference

972058
stoichiometry: 1.0
species: 894759
type: SpeciesReference

936000
stoichiometry: 4.0
species: 891616
type: SpeciesReference

005947
stoichiometry: 2.0
species: 891555
type: SpeciesReference

973000
stoichiometry: 1.0
species: 894711
type: SpeciesReference

004449
stoichiometry: 1.0
species: 884826
type: SpeciesReference

896100
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1720H2828N20O570P20
type: Species

918193
stoichiometry: 2.0
species: 882781
type: SpeciesReference

008050
stoichiometry: 1.0
species: 882781
type: SpeciesReference

889625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Gal-Gal-Gal-Gal-Gal-Glc-Cer (homo sapiens)_C54H96NO32FULLRCO
type: Species

906871
reactant: 962295
reactant: 962319
is: http://identifiers.org/ec-code/1.14.16.4
is: ENSPTRG00000003409.2
is: ENSPTRG00000005229.4
notes: R_TRPHYDRO2 subsystem: Tryptophan metabolism R_TRPHYDRO2 equation: [c] : o2 + thbpt + trp-L --> 5htrp + thbpt4acam
product: 962343
type: Reaction
product: 962331
reactant: 962307
reversible: false
fast: false
name: L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)

908025
stoichiometry: 2.0
species: 897552
type: SpeciesReference

995082
stoichiometry: 1.0
species: 901826
type: SpeciesReference

953616
stoichiometry: 2.0
species: 898539
type: SpeciesReference

942656
stoichiometry: 1.0
species: 887033
type: SpeciesReference

951199
stoichiometry: 1.0
species: 897273
type: SpeciesReference

993042
stoichiometry: 1.0
species: 887266
type: SpeciesReference

909741
reactant: 988494
fast: false
notes: R_DHFR subsystem: Folate Metabolism R_DHFR equation: [c] : dhf + h + nadph <==> nadp + thf R_FOLR2 subsystem: Folate Metabolism R_FOLR2 equation: [c] : fol + nadph --> dhf + nadp
modifier: 988568
is: ENSPTRG00000021155.5
is: http://identifiers.org/ec-code/1.5.1.3
modifier: 988530
modifier: 988543
type: Reaction
modifier: 988580
modifier: 988556
product: 988518
product: 988506
reactant: 988482
reversible: false

924148
stoichiometry: 1.0
species: 890518
type: SpeciesReference

950532
stoichiometry: 9.0
species: 885901
type: SpeciesReference

882757
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Aspartate_C4H6NO4
type: Species

907822
notes: R_TMDK1 subsystem: Nucleotides R_TMDK1 equation: [c] : atp + thymd --> adp + dtmp + h R_DURIK1 subsystem: Nucleotides R_DURIK1 equation: [c] : atp + duri --> adp + dump + h
product: 970430
product: 970467
fast: false
reactant: 970406
is: http://identifiers.org/ec-code/2.7.1.21
product: 970455
reversible: false
product: 970442
reactant: 970418
is: ENSPTRG00000009704.4
reactant: 970394
type: Reaction

944833
stoichiometry: 1.0
species: 892401
type: SpeciesReference

882224
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: androsterone glucuronide_C25H38O8
type: Species

943246
stoichiometry: 2.0
species: 891748
type: SpeciesReference

957355
stoichiometry: 1.0
species: 889827
type: SpeciesReference

960099
stoichiometry: 1.0
species: 880183
type: SpeciesReference

961763
stoichiometry: 1.0
species: 898744
type: SpeciesReference

907821
stoichiometry: 32.0
species: 880523
type: SpeciesReference

915030
stoichiometry: 2.0
species: 889334
type: SpeciesReference

979823
stoichiometry: 1.0
species: 891591
type: SpeciesReference

004557
stoichiometry: 1.0
species: 877468
type: SpeciesReference

890530
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Glycine_C2H5NO2
type: Species

987422
stoichiometry: 2.0
species: 896124
type: SpeciesReference

956907
stoichiometry: 1.0
species: 902475
type: SpeciesReference

905164
type: Reaction
product: 945520
is: ENSPTRG00000000748.4
reactant: 945496
product: 945568
reactant: 945483
product: 945544
modifier: 945616
reactant: 945471
modifier: 945604
notes: R_SCP3x subsystem: Bile Acid Biosynthesis R_SCP3x equation: [x] : coa + dhcholestancoa + o2 --> dcholcoa + h2o + ppcoa R_SCPx subsystem: Bile Acid Biosynthesis R_SCPx equation: [x] : cholcoaone + coa --> cholcoa + ppcoa R_SCP21x subsystem: Transport, Peroxisomal R_SCP21x equation: phytcoa[c] <==> phytcoa[x] R_SCP2x subsystem: Bile Acid Biosynthesis R_SCP2x equation: [x] : coa + dhocholoylcoa --> dgcholcoa + ppcoa R_SCP22x subsystem: Transport, Peroxisomal R_SCP22x equation: dmnoncoa[c] <==> dmnoncoa[x]
modifier: 945592
modifier: 945580
product: 945532
reactant: 945508
reversible: false
fast: false
product: 945556
reactant: 945459

897912
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Sulfate derivative of norepinephrine_C8H11NO6S
type: Species

883482
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Cob(II)alamin_C62H92CoN13O14P
type: Species

903005
product: 928769
fast: false
reactant: 928745
product: 928757
type: Reaction
product: 928781
reversible: true
reactant: 928733
is: ENSPTRG00000008919.5
reactant: 928721
notes: R_CITt4_2 subsystem: Transport, Extracellular R_CITt4_2 equation: cit[e] + (2) na1[e] <==> cit[c] + (2) na1[c] R_SUCCt4_2 subsystem: Transport, Extracellular R_SUCCt4_2 equation: (2) na1[e] + succ[e] <==> (2) na1[c] + succ[c]

962259
stoichiometry: 2.0
species: 877032
type: SpeciesReference

974195
stoichiometry: 1.0
species: 881499
type: SpeciesReference

950242
stoichiometry: 1.0
species: 882469
type: SpeciesReference

953083
stoichiometry: 2.0
species: 880486
type: SpeciesReference

970334
stoichiometry: 1.0
species: 899578
type: SpeciesReference

951635
stoichiometry: 8.0
species: 897273
type: SpeciesReference

881270
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: ADP_C10H12N5O10P2
type: Species

944773
stoichiometry: 1.0
species: 881608
type: SpeciesReference

960847
stoichiometry: 2.0
species: 884013
type: SpeciesReference

965486
stoichiometry: 2.0
species: 903728
type: SpeciesReference

907063
stoichiometry: 1.0
species: 883747
type: SpeciesReference

930352
stoichiometry: 1.0
species: 898236
type: SpeciesReference

993259
stoichiometry: 1.0
species: 881933
type: SpeciesReference

893102
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Isoleucine_C6H13NO2
type: Species

994636
stoichiometry: 1.0
species: 898080
type: SpeciesReference

000214
stoichiometry: 1.0
species: 882781
type: SpeciesReference

915018
stoichiometry: 2.0
species: 904585
type: SpeciesReference

972952
stoichiometry: 1.0
species: 895099
type: SpeciesReference

898636
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phosphatidic acid (homo sapiens)_C3H5O4PFULLRCO2FULLR2CO2
type: Species

904814
product: 943926
product: 943913
notes: R_HMGCOASim subsystem: Cholesterol Metabolism R_HMGCOASim equation: [m] : aacoa + accoa + h2o --> coa + h + hmgcoa
is: http://identifiers.org/ec-code/4.1.3.5
is: ENSPTRG00000001179.2
fast: false
name: Hydroxymethylglutaryl CoA synthase (ir)
reactant: 943900
reversible: false
reactant: 943887
reactant: 943874
product: 943939
type: Reaction

909845
stoichiometry: 1.0
species: 877324
type: SpeciesReference

994781
stoichiometry: 1.0
species: 897492
type: SpeciesReference

928336
stoichiometry: 4.0
species: 891483
type: SpeciesReference

892425
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 18_C43H66N2O45S3
type: Species

900605
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Pantetheine_C11H22N2O4S
type: Species

983531
stoichiometry: 1.0
species: 885562
type: SpeciesReference

927151
stoichiometry: 2.0
species: 898032
type: SpeciesReference

955556
stoichiometry: 1.0
species: 891591
type: SpeciesReference

969877
stoichiometry: 6.0
species: 891640
type: SpeciesReference

995178
stoichiometry: 1.0
species: 887873
type: SpeciesReference

976113
stoichiometry: 1.0
species: 887837
type: SpeciesReference

929275
stoichiometry: 1.0
species: 881740
type: SpeciesReference

905764
notes: R_NADS2 subsystem: NAD Metabolism R_NADS2 equation: [c] : atp + dnad + gln-L + h2o --> amp + glu-L + h + nad + ppi
is: ENSPTRG00000004014.3
reactant: 952817
product: 952890
reactant: 952854
product: 952866
is: http://identifiers.org/ec-code/6.3.5.1
product: 952878
type: Reaction
reactant: 952830
reversible: false
product: 952902
reactant: 952842
name: NAD synthase (glutamine-hydrolysing)
fast: false
product: 952914

956714
stoichiometry: 1.0
species: 892061
type: SpeciesReference

940043
stoichiometry: 1.0
species: 895012
type: SpeciesReference

929540
stoichiometry: 1.0
species: 899904
type: SpeciesReference

981516
stoichiometry: 4.0
species: 891495
type: SpeciesReference

886793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
type: Species

887897
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Eicosatetranoyl carnitine_C27H45NO4
type: Species

928529
stoichiometry: 1.0
species: 888986
type: SpeciesReference

008038
stoichiometry: 1.0
species: 882322
type: SpeciesReference

909203
stoichiometry: 2.0
species: 899807
type: SpeciesReference

957885
stoichiometry: 1.0
species: 891483
type: SpeciesReference

973868
stoichiometry: 2.0
species: 891531
type: SpeciesReference

912505
stoichiometry: 1.0
species: 880377
type: SpeciesReference

904813
stoichiometry: 1.0
species: 879859
type: SpeciesReference

883398
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: cAMP_C10H11N5O6P
type: Species

900606
product: 910512
notes: R_M16NTg subsystem: N-Glycan Biosynthesis R_M16NTg equation: [g] : nm2masn + uacgam --> h + n2m2masn + udp
is: http://identifiers.org/ec-code/2.4.1.143
fast: false
product: 910500
type: Reaction
is: ENSPTRG00000012135.3
name: alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
product: 910488
reactant: 910463
reversible: false
reactant: 910476

911722
stoichiometry: 2.0
species: 893247
type: SpeciesReference

998103
stoichiometry: 3.0
species: 884085
type: SpeciesReference

976946
stoichiometry: 9.0
species: 883531
type: SpeciesReference

976657
stoichiometry: 3.0
species: 885840
type: SpeciesReference

955616
stoichiometry: 4.0
species: 899009
type: SpeciesReference

909729
product: 988470
reactant: 988445
type: Reaction
reversible: true
is: ENSPTRG00000023465.1
product: 988457
reactant: 988433
is: ENSPTRG00000014156.4
notes: R_FRUt1r subsystem: Transport, Extracellular R_FRUt1r equation: fru[e] <==> fru[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]
fast: false

954239
stoichiometry: 1.0
species: 895350
type: SpeciesReference

005308
stoichiometry: 2.0
species: 897395
type: SpeciesReference

981965
stoichiometry: 1.0
species: 902186
type: SpeciesReference

973217
stoichiometry: 1.0
species: 890434
type: SpeciesReference

913638
stoichiometry: 1.0
species: 881258
type: SpeciesReference

932899
stoichiometry: 1.0
species: 880317
type: SpeciesReference

978470
stoichiometry: 1.0
species: 892049
type: SpeciesReference

959581
stoichiometry: 1.0
species: 897395
type: SpeciesReference

939667
stoichiometry: 1.0
species: 888406
type: SpeciesReference

950955
stoichiometry: 5.0
species: 891616
type: SpeciesReference

929940
stoichiometry: 1.0
species: 897552
type: SpeciesReference

953936
stoichiometry: 1.0
species: 889250
type: SpeciesReference

965258
stoichiometry: 1.0
species: 891640
type: SpeciesReference

968883
stoichiometry: 1.0
species: 891591
type: SpeciesReference

876656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: _10-Formyltetrahydrofolate_C20H21N7O7
type: Species

989533
stoichiometry: 1.0
species: 903680
type: SpeciesReference

911878
stoichiometry: 1.0
species: 880195
type: SpeciesReference

895164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Leukotriene A4_C20H29O3
type: Species

954179
stoichiometry: 1.0
species: 896559
type: SpeciesReference

902620
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5
type: Species

901245
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Sorbitol_C6H14O6
type: Species

921374
stoichiometry: 1.0
species: 881125
type: SpeciesReference

933527
stoichiometry: 1.0
species: 880195
type: SpeciesReference

906667
notes: R_CITtbm subsystem: Transport, Mitochondrial R_CITtbm equation: cit[c] + pep[m] <==> cit[m] + pep[c] R_CITtam subsystem: Transport, Mitochondrial R_CITtam equation: cit[c] + mal-L[m] <==> cit[m] + mal-L[c]
reactant: 960835
reactant: 960823
reversible: true
is: ENSPTRG00000014057.3
product: 960859
reactant: 960847
product: 960883
fast: false
type: Reaction
product: 960871

891808
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Hexadecanoate (n-C16:0)_C16H31O2
type: Species

952237
stoichiometry: 1.0
species: 880523
type: SpeciesReference

992304
stoichiometry: 4.0
species: 891591
type: SpeciesReference

880909
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Acetyl-D-mannosamine_C8H15NO6
type: Species

890326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Glutamate_C5H8NO4
type: Species

957342
stoichiometry: 10.0
species: 897321
type: SpeciesReference

908586
notes: R_PI45P3K subsystem: Inositol Phosphate Metabolism R_PI45P3K equation: [c] : atp + pail45p_hs --> adp + h + pail345p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs
reversible: false
is: ENSPTRG00000015452.2
type: Reaction
reactant: 979462
is: ENSPTRG00000008751.3
reactant: 979510
is: ENSPTRG00000016940.3
is: ENSPTRG00000019573.4
is: ENSPTRG00000000685.5
product: 979546
product: 979534
reactant: 979486
is: http://identifiers.org/ec-code/2.7.1.137
product: 979582
product: 979570
reactant: 979474
is: ENSPTRG00000010875.3
fast: false
is: ENSPTRG00000010694.3
is: ENSPTRG00000005858.5
product: 979522
reactant: 979498
is: ENSPTRG00000015642.2
is: http://identifiers.org/ec-code/2.7.1.153
product: 979558

911879
is: http://identifiers.org/ec-code/3.5.1.23
is: ENSPTRG00000011796.4
notes: R_ASAH1 subsystem: Sphingolipid Metabolism R_ASAH1 equation: [l] : crm_hs + h2o --> Rtotal + sphings
reactant: 008682
reactant: 008670
name: N-acylsphingosine amidohydrolase
fast: false
product: 008694
type: Reaction
product: 008707
reversible: false

982145
stoichiometry: 1.0
species: 891483
type: SpeciesReference

924994
stoichiometry: 1.0
species: 897516
type: SpeciesReference

925043
stoichiometry: 1.0
species: 897443
type: SpeciesReference

923739
stoichiometry: 1.0
species: 903113
type: SpeciesReference

901246
is: ENSPTRG00000016692.4
product: 915114
reactant: 915066
product: 915126
product: 915102
is: ENSPTRG00000006879.5
type: Reaction
notes: R_KCC2t subsystem: Transport, Extracellular R_KCC2t equation: cl[e] + nh4[e] <==> cl[c] + nh4[c] R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]
reactant: 915090
reversible: true
reactant: 915078
is: ENSPTRG00000033921.1
fast: false

909517
stoichiometry: 1.0
species: 879571
type: SpeciesReference

882949
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Bilirubin beta-diglucuronide_C45H50N4O18
type: Species

956485
stoichiometry: 1.0
species: 879979
type: SpeciesReference

001893
stoichiometry: 1.0
species: 903125
type: SpeciesReference

904537
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Xyl-L-Ser (protein)_C5H9O4X
type: Species

010345
stoichiometry: 1.0
species: 891483
type: SpeciesReference

907293
modifier: 964655
reactant: 964508
reactant: 964520
modifier: 964618
modifier: 964606
fast: false
product: 964581
product: 964557
product: 964594
reactant: 964472
reactant: 964496
reactant: 964484
modifier: 964630
reactant: 964460
product: 964545
product: 964532
is: http://identifiers.org/ec-code/1.1.1.1
product: 964569
notes: R_ALCD22_D subsystem: Pyruvate Metabolism R_ALCD22_D equation: [c] : lald-D + nad --> h + mthgxl + nadh R_ALCD1 subsystem: Miscellaneous R_ALCD1 equation: [c] : meoh + nad <==> fald + h + nadh R_ALCD2if subsystem: Glycolysis/Gluconeogenesis R_ALCD2if equation: [c] : etoh + nad --> acald + h + nadh R_ALCD21_D subsystem: Pyruvate Metabolism R_ALCD21_D equation: [c] : 12ppd-R + nad --> h + lald-D + nadh R_ALCD22_L subsystem: Pyruvate Metabolism R_ALCD22_L equation: [c] : lald-L + nad --> h + mthgxl + nadh R_ALCD21_L subsystem: Pyruvate Metabolism R_ALCD21_L equation: [c] : 12ppd-S + nad --> h + lald-L + nadh
type: Reaction
reversible: false
is: ENSPTRG00000010119.3
modifier: 964643
is: http://identifiers.org/ec-code/1.1.1.78
is: http://identifiers.org/ec-code/1.2.1.49

930122
stoichiometry: 1.0
species: 878361
type: SpeciesReference

001281
stoichiometry: 1.0
species: 899396
type: SpeciesReference

948183
stoichiometry: 1.0
species: 898430
type: SpeciesReference

885272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 4_C31H46NO38S4
type: Species

909724
stoichiometry: 3.0
species: 891664
type: SpeciesReference

993899
stoichiometry: 3.0
species: 897261
type: SpeciesReference

972373
stoichiometry: 1.0
species: 890868
type: SpeciesReference

894699
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate II (core 4-linked), degradation product 2_C78H127N6O61S2X
type: Species

002426
stoichiometry: 2.0
species: 901438
type: SpeciesReference

005502
stoichiometry: 1.0
species: 904645
type: SpeciesReference

878289
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _4,8-Dihydroxyquinoline_C9H7NO2
type: Species

909849
reactant: 990601
is: ENSPTRG00000007096.4
notes: R_BMTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_L equation: [r] : (0.1) dolmanp_L + memgacpail_hs --> (0.1) dolp_L + h + m2emgacpail_hs R_BMTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_BMTer_U equation: [r] : (0.1) dolmanp_U + memgacpail_hs --> (0.1) dolp_U + h + m2emgacpail_hs R_H3MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_L equation: [r] : (0.1) dolmanp_L + m2gacpail_hs --> (0.1) dolp_L + h + m3gacpail_hs R_H3MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H3MTer_U equation: [r] : (0.1) dolmanp_U + m2gacpail_hs --> (0.1) dolp_U + h + m3gacpail_hs
reactant: 990589
product: 990662
reversible: false
product: 990625
fast: false
reactant: 990613
type: Reaction
product: 990650
product: 990674
product: 990637
reactant: 990577

997716
stoichiometry: 1.0
species: 881897
type: SpeciesReference

932259
stoichiometry: 1.0
species: 889358
type: SpeciesReference

968208
stoichiometry: 1.0
species: 892729
type: SpeciesReference

957125
stoichiometry: 1.0
species: 899069
type: SpeciesReference

990454
stoichiometry: 1.0
species: 889742
type: SpeciesReference

004353
stoichiometry: 1.0
species: 885188
type: SpeciesReference

911589
stoichiometry: 1.0
species: 899238
type: SpeciesReference

904682
reactant: 943065
is: http://identifiers.org/ec-code/2.7.1.24
modifier: 943162
type: Reaction
is: ENSPTRG00000009207.4
product: 943089
is: http://identifiers.org/ec-code/2.7.7.3
modifier: 943137
product: 943113
reversible: false
notes: R_PTPAT subsystem: CoA Biosynthesis R_PTPAT equation: [c] : atp + h + pan4p <==> dpcoa + ppi R_DPCOAK subsystem: CoA Biosynthesis R_DPCOAK equation: [c] : atp + dpcoa --> adp + coa + h
product: 943101
reactant: 943077
fast: false
modifier: 943174
modifier: 943125
modifier: 943150

941784
stoichiometry: 1.0
species: 893382
type: SpeciesReference

922097
stoichiometry: 1.0
species: 881005
type: SpeciesReference

925632
stoichiometry: 2.0
species: 901525
type: SpeciesReference

962573
stoichiometry: 1.0
species: 881210
type: SpeciesReference

946110
stoichiometry: 1.0
species: 881656
type: SpeciesReference

009827
stoichiometry: 1.0
species: 891038
type: SpeciesReference

894819
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate II biosynthesis, precursor 5_C69H112N6O48X
type: Species

937811
stoichiometry: 1.0
species: 884439
type: SpeciesReference

987651
stoichiometry: 2.0
species: 902716
type: SpeciesReference

903862
product: 935481
product: 935469
product: 935433
reactant: 935373
type: Reaction
product: 935457
notes: R_ADRNLPVESSEC subsystem: Transport, Extracellular R_ADRNLPVESSEC equation: (3) adrnl[c] + (2) atp[c] + (2) h2o[c] --> (2) adp[c] + (3) adrnl[e] + (2) h[c] + (2) pi[c] R_5HTRPVESSEC subsystem: Transport, Extracellular R_5HTRPVESSEC equation: (3) 5htrp[c] + (2) atp[c] + (2) h2o[c] --> (3) 5htrp[e] + (2) adp[c] + (2) h[c] + (2) pi[c] R_NRPPHRVESSEC subsystem: Transport, Extracellular R_NRPPHRVESSEC equation: (2) atp[c] + (2) h2o[c] + (3) nrpphr[c] --> (2) adp[c] + (2) h[c] + (3) nrpphr[e] + (2) pi[c] R_HISTAVESSEC subsystem: Transport, Extracellular R_HISTAVESSEC equation: (2) atp[c] + (2) h2o[c] + (3) hista[c] --> (2) adp[c] + (2) h[c] + (3) hista[e] + (2) pi[c] R_DOPAVESSEC subsystem: Transport, Extracellular R_DOPAVESSEC equation: (2) atp[c] + (3) dopa[c] + (2) h2o[c] --> (2) adp[c] + (3) dopa[e] + (2) h[c] + (2) pi[c]
reactant: 935361
is: ENSPTRG00000020039.5
reactant: 935409
product: 935421
is: ENSPTRG00000002979.5
reactant: 935397
product: 935505
reactant: 935385
product: 935493
reactant: 935337
product: 935445
reactant: 935349
reversible: false
fast: false

915778
stoichiometry: 1.0
species: 897516
type: SpeciesReference

960654
stoichiometry: 5.0
species: 881258
type: SpeciesReference

995926
stoichiometry: 3.0
species: 891591
type: SpeciesReference

904681
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Zymostenol_C27H46O
type: Species

887009
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

001497
stoichiometry: 1.0
species: 893804
type: SpeciesReference

907291
stoichiometry: 8.0
species: 903488
type: SpeciesReference

883179
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Biotin_C10H15N2O3S
type: Species

958962
stoichiometry: 1.0
species: 897285
type: SpeciesReference

908583
stoichiometry: 3.0
species: 890034
type: SpeciesReference

946242
stoichiometry: 2.0
species: 899530
type: SpeciesReference

999476
stoichiometry: 1.0
species: 883203
type: SpeciesReference

922953
stoichiometry: 1.0
species: 894224
type: SpeciesReference

899033
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2
type: Species

905263
stoichiometry: 27.0
species: 891591
type: SpeciesReference

004680
stoichiometry: 2.0
species: 880317
type: SpeciesReference

917103
stoichiometry: 1.0
species: 895617
type: SpeciesReference

906664
stoichiometry: 5.0
species: 899542
type: SpeciesReference

919474
stoichiometry: 1.0
species: 882139
type: SpeciesReference

002847
stoichiometry: 1.0
species: 895629
type: SpeciesReference

911723
is: ENSPTRG00000002516.3
reactant: 007651
reactant: 007689
is: http://identifiers.org/ec-code/2.7.1.151
reactant: 007663
reactant: 007639
product: 007738
reactant: 007676
product: 007713
fast: false
is: http://identifiers.org/ec-code/2.7.1.140
product: 007701
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.127
notes: R_MI145P6Kn subsystem: Inositol Phosphate Metabolism R_MI145P6Kn equation: [n] : atp + mi145p --> adp + h + mi1456p R_MI1456PKn subsystem: Inositol Phosphate Metabolism R_MI1456PKn equation: [n] : atp + mi1456p --> adp + h + mi13456p R_MI1346PKn subsystem: Inositol Phosphate Metabolism R_MI1346PKn equation: [n] : atp + mi1346p --> adp + h + mi13456p R_MI1345PKn subsystem: Inositol Phosphate Metabolism R_MI1345PKn equation: [n] : atp + mi1345p --> adp + h + mi13456p R_MI145PKn subsystem: Inositol Phosphate Metabolism R_MI145PKn equation: [n] : atp + mi145p --> adp + h + mi1345p
product: 007726
product: 007750
reversible: false

890770
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: glycogen, structure 4 (glycogenin-1,6-{2[1,4-Glc], [1,4-Glc]})_C18H31O16X
type: Species

004789
stoichiometry: 1.0
species: 878000
type: SpeciesReference

955232
stoichiometry: 6.0
species: 897321
type: SpeciesReference

963102
stoichiometry: 1.0
species: 899578
type: SpeciesReference

920855
stoichiometry: 1.0
species: 891555
type: SpeciesReference

878060
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _3-Oxohexadecanoyl-CoA_C37H60N7O18P3S
type: Species

940901
stoichiometry: 2.0
species: 891591
type: SpeciesReference

899335
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: phosphatidylglycerol (homo sapiens)_C6H12O6PFULLRCO2FULLR2CO2
type: Species

953820
stoichiometry: 1.0
species: 900340
type: SpeciesReference

972481
stoichiometry: 7.0
species: 890155
type: SpeciesReference

944605
stoichiometry: 1.0
species: 896004
type: SpeciesReference

987855
stoichiometry: 1.0
species: 891483
type: SpeciesReference

909201
reactant: 983555
is: http://identifiers.org/ec-code/4.4.1.16
product: 983615
notes: R_SELCYSLY2 subsystem: Selenoamino acid metabolism R_SELCYSLY2 equation: [c] : pdx5p + selcys --> ala-L + h + pydx5p + seln R_SELCYSLY subsystem: Selenoamino acid metabolism R_SELCYSLY equation: [c] : dtt + selcys --> ala-L + dttOX + h + seln
product: 983591
fast: false
product: 983603
product: 983579
type: Reaction
reversible: false
reactant: 983543
product: 983627
is: ENSPTRG00000013082.4
reactant: 983567

980210
stoichiometry: 1.0
species: 891326
type: SpeciesReference

892159
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

898382
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)_C29H53N2O8PRS
type: Species

884210
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: CMP_C9H12N3O8P
type: Species

909513
is: http://identifiers.org/ec-code/1.2.1.3
product: 986350
modifier: 986411
modifier: 986435
modifier: 986374
reactant: 986106
modifier: 986459
product: 986229
modifier: 986423
modifier: 986362
modifier: 986447
modifier: 986386
product: 986338
product: 986265
reactant: 986193
reactant: 986143
product: 986313
modifier: 986507
fast: false
reactant: 986131
is: http://identifiers.org/ec-code/1.2.1.21
modifier: 986471
notes: R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhmald + h2o + nadp <==> 34dhoxmand + (2) h + nadph R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_34DHPLACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHPLACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhpac + h2o + nadp <==> 34dhpha + (2) h + nadph R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsy…
product: 986241
modifier: 986495
modifier: 986519
modifier: 986543
reversible: false
modifier: 986483
reactant: 986094
modifier: 986531
type: Reaction
reactant: 986082
product: 986217
reactant: 986070
reactant: 986180
is: http://identifiers.org/ec-code/1.2.1.4
is: http://identifiers.org/ec-code/1.2.1.5
product: 986326
reactant: 986119
is: http://identifiers.org/ec-code/1.2.1.39
product: 986277
product: 986301
product: 986289
reactant: 986205
is: ENSPTRG00000003974.3
modifier: 986399
product: 986253
reactant: 986168
reactant: 986156

893526
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 16_C160H258N11O137S7
type: Species

991941
stoichiometry: 1.0
species: 902788
type: SpeciesReference

910620
stoichiometry: 1.0
species: 896752
type: SpeciesReference

890204
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: D-Glucose_C6H12O6
type: Species

947737
stoichiometry: 20.0
species: 891616
type: SpeciesReference

990722
stoichiometry: 1.0
species: 904525
type: SpeciesReference

943450
stoichiometry: 1.0
species: 892704
type: SpeciesReference

005019
stoichiometry: 1.0
species: 891555
type: SpeciesReference

876825
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _13-cis-retinoyl glucuronide_C26H35O8
type: Species

910343
stoichiometry: 1.0
species: 898816
type: SpeciesReference

913374
stoichiometry: 17.0
species: 897273
type: SpeciesReference

927596
stoichiometry: 1.0
species: 881740
type: SpeciesReference

946786
stoichiometry: 1.0
species: 882781
type: SpeciesReference

917792
stoichiometry: 1.0
species: 882937
type: SpeciesReference

995283
stoichiometry: 1.0
species: 887021
type: SpeciesReference

997825
stoichiometry: 1.0
species: 899372
type: SpeciesReference

897780
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C54H90N3O40X
type: Species

978858
stoichiometry: 1.0
species: 898297
type: SpeciesReference

901500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-sulfolactate_C3H4O6S
type: Species

947629
stoichiometry: 1.0
species: 894383
type: SpeciesReference

910342
reactant: 993210
product: 993247
is: http://identifiers.org/ec-code/2.6.1.44
notes: R_SPTix subsystem: Glycine, Serine, and Threonine Metabolism R_SPTix equation: [x] : pyr + ser-L --> ala-L + hpyr R_AGTix subsystem: Alanine and Aspartate Metabolism R_AGTix equation: [x] : ala-L + glx --> gly + pyr
reactant: 993222
reversible: false
product: 993271
type: Reaction
product: 993259
reactant: 993234
reactant: 993198
is: ENSPTRG00000013113.4
fast: false
product: 993283

876935
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _1-alpha,25-Dihydroxyvitamin D2_C28H44O3
type: Species

888249
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Ethanolamine phosphate_C2H7NO4P
type: Species

915175
stoichiometry: 1.0
species: 900580
type: SpeciesReference

936146
stoichiometry: 2.0
species: 881620
type: SpeciesReference

941686
stoichiometry: 1.0
species: 887461
type: SpeciesReference

976729
stoichiometry: 7.0
species: 885961
type: SpeciesReference

982037
stoichiometry: 1.0
species: 889863
type: SpeciesReference

965024
stoichiometry: 1.0
species: 897225
type: SpeciesReference

910776
stoichiometry: 1.0
species: 890638
type: SpeciesReference

903752
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: UMP_C9H11N2O9P
type: Species

908365
is: ENSPTRG00000032613.2
product: 977019
is: ENSPTRG00000028809.3
reactant: 976994
is: ENSPTRG00000017688.3
type: Reaction
reactant: 976958
is: ENSPTRG00000028851.3
product: 977043
product: 977031
reactant: 976982
notes: R_OXAHCOtex subsystem: Transport, Extracellular R_OXAHCOtex equation: (2) hco3[c] + oxa[e] --> (2) hco3[e] + oxa[c] R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e]
product: 977006
is: ENSPTRG00000028840.3
reversible: false
is: ENSPTRG00000017405.3
fast: false
is: ENSPTRG00000028808.3
reactant: 976970

984905
stoichiometry: 1.0
species: 885599
type: SpeciesReference

909357
reversible: false
modifier: 984821
product: 984808
is: http://identifiers.org/ec-code/4.2.1.17
modifier: 984893
notes: R_ECOAH12m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH12m equation: [m] : 2mp2coa + h2o <==> 3hibutcoa R_PRPNCOAHYDm subsystem: beta-Alanine metabolism R_PRPNCOAHYDm equation: [m] : h2o + prpncoa --> 3hpcoa R_ECOAH9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_ECOAH9m equation: [m] : 2mb2coa + h2o <==> 3hmbcoa R_ECOAH1m subsystem: Tryptophan metabolism R_ECOAH1m equation: [m] : 3hbcoa <==> b2coa + h2o
modifier: 984881
is: ENSPTRG00000003094.3
fast: false
modifier: 984869
reactant: 984784
type: Reaction
modifier: 984857
reactant: 984796
modifier: 984845
modifier: 984833

994551
stoichiometry: 2.0
species: 896016
type: SpeciesReference

002775
stoichiometry: 1.0
species: 897552
type: SpeciesReference

893876
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 41_C34H58N2O26
type: Species

948452
stoichiometry: 11.0
species: 898260
type: SpeciesReference

901130
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57
type: Species

920927
stoichiometry: 1.0
species: 890167
type: SpeciesReference

878397
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _4-Fumarylacetoacetate_C8H6O6
type: Species

968316
stoichiometry: 1.0
species: 892789
type: SpeciesReference

915887
stoichiometry: 1.0
species: 892073
type: SpeciesReference

932367
stoichiometry: 2.0
species: 891531
type: SpeciesReference

004461
stoichiometry: 1.0
species: 889754
type: SpeciesReference

006139
stoichiometry: 1.0
species: 903909
type: SpeciesReference

895012
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: D-Lactaldehyde_C3H6O2
type: Species

957017
stoichiometry: 1.0
species: 898032
type: SpeciesReference

007639
stoichiometry: 1.0
species: 896801
type: SpeciesReference

916707
stoichiometry: 1.0
species: 895520
type: SpeciesReference

000759
stoichiometry: 1.0
species: 879510
type: SpeciesReference

919582
stoichiometry: 1.0
species: 903161
type: SpeciesReference

906556
stoichiometry: 1.0
species: 893054
type: SpeciesReference

881427
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: adrenic acid_C22H35O2
type: Species

953412
stoichiometry: 1.0
species: 883651
type: SpeciesReference

900981
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: retinoyl glucuronide_C26H35O8
type: Species

918723
stoichiometry: 1.0
species: 877963
type: SpeciesReference

962682
stoichiometry: 1.0
species: 877105
type: SpeciesReference

982470
stoichiometry: 1.0
species: 886624
type: SpeciesReference

947086
stoichiometry: 1.0
species: 877938
type: SpeciesReference

956593
stoichiometry: 1.0
species: 880099
type: SpeciesReference

941893
stoichiometry: 1.0
species: 891302
type: SpeciesReference

951779
stoichiometry: 1.0
species: 890362
type: SpeciesReference

955340
stoichiometry: 1.0
species: 891555
type: SpeciesReference

994407
stoichiometry: 1.0
species: 896052
type: SpeciesReference

946678
stoichiometry: 1.0
species: 897261
type: SpeciesReference

880607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: alpha GalNAc globoside (homo sapiens)_C52H92N3O27FULLRCO
type: Species

004077
stoichiometry: 4.0
species: 894480
type: SpeciesReference

912130
stoichiometry: 1.0
species: 887971
type: SpeciesReference

939223
stoichiometry: 1.0
species: 881342
type: SpeciesReference

893948
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 9_C188H301N13O166S10
type: Species

913482
stoichiometry: 1.0
species: 896631
type: SpeciesReference

923895
stoichiometry: 1.0
species: 887667
type: SpeciesReference

903754
fast: false
product: 934577
notes: R_TYRTAm subsystem: Tyrosine metabolism R_TYRTAm equation: [m] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1m subsystem: Phenylalanine metabolism R_PHETA1m equation: [m] : akg + phe-L <==> glu-L + phpyr
is: http://identifiers.org/ec-code/2.6.1.58
reversible: true
type: Reaction
reactant: 934529
product: 934565
is: http://identifiers.org/ec-code/2.6.1.5
is: ENSPTRG00000005135.4
product: 934589
reactant: 934553
reactant: 934541

916815
stoichiometry: 1.0
species: 901922
type: SpeciesReference

950991
stoichiometry: 1.0
species: 885356
type: SpeciesReference

905372
stoichiometry: 1.0
species: 892607
type: SpeciesReference

953712
stoichiometry: 1.0
species: 877746
type: SpeciesReference

980366
stoichiometry: 1.0
species: 889802
type: SpeciesReference

010563
stoichiometry: 1.0
species: 880523
type: SpeciesReference

932669
stoichiometry: 1.0
species: 899795
type: SpeciesReference

882661
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Ascorbate_C6H8O6
type: Species

905260
is: http://identifiers.org/ec-code/1.13.11.33
reactant: 946278
type: Reaction
product: 946290
notes: R_ALOX15 subsystem: Eicosanoid Metabolism R_ALOX15 equation: [c] : arachd + o2 --> 15HPET
reversible: false
fast: false
is: ENSPTRG00000008597.1
name: Arachidonate 15-lipoxygenase
reactant: 946266

903161
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Tryptophan_C11H12N2O2
type: Species

911435
reactant: 004461
type: Reaction
is: ENSPTRG00000017357.4
fast: false
reversible: false
notes: R_G6PDA subsystem: Aminosugar Metabolism R_G6PDA equation: [c] : gam6p + h2o --> f6p + nh4
reactant: 004473
product: 004485
name: glucosamine-6-phosphate deaminase
is: http://identifiers.org/ec-code/3.5.99.6
is: ENSPTRG00000016023.3
product: 004497

997304
stoichiometry: 3.0
species: 898080
type: SpeciesReference

989774
stoichiometry: 1.0
species: 894297
type: SpeciesReference

906314
stoichiometry: 2.0
species: 891640
type: SpeciesReference

003728
stoichiometry: 1.0
species: 885043
type: SpeciesReference

916115
stoichiometry: 1.0
species: 896897
type: SpeciesReference

937243
stoichiometry: 1.0
species: 892085
type: SpeciesReference

990831
stoichiometry: 1.0
species: 882176
type: SpeciesReference

954447
stoichiometry: 1.0
species: 890590
type: SpeciesReference

005610
stoichiometry: 1.0
species: 896487
type: SpeciesReference

961727
stoichiometry: 1.0
species: 903440
type: SpeciesReference

999368
stoichiometry: 8.0
species: 891591
type: SpeciesReference

946350
stoichiometry: 1.0
species: 897708
type: SpeciesReference

951923
stoichiometry: 1.0
species: 889827
type: SpeciesReference

908366
stoichiometry: 1.0
species: 901354
type: SpeciesReference

001341
stoichiometry: 1.0
species: 888514
type: SpeciesReference

898491
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: hydroxide ion_HO
type: Species

982698
stoichiometry: 1.0
species: 878180
type: SpeciesReference

961017
stoichiometry: 1.0
species: 898997
type: SpeciesReference

898744
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens)_C9H13O18P4FULLRCO2FULLR2CO2
type: Species

929384
stoichiometry: 1.0
species: 896475
type: SpeciesReference

901923
product: 919716
product: 919704
product: 919692
reactant: 919643
product: 919680
reversible: true
type: Reaction
reactant: 919668
fast: false
reactant: 919607
product: 919728
reactant: 919619
is: ENSPTRG00000000623.4
product: 919740
reactant: 919655
reactant: 919631
notes: R_GALt1r subsystem: Transport, Extracellular R_GALt1r equation: gal[e] <==> gal[c] R_GAMt1r subsystem: Transport, Extracellular R_GAMt1r equation: gam[e] <==> gam[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c] R_DHAAt1r subsystem: Transport, Extracellular R_DHAAt1r equation: dhdascb[e] <==> dhdascb[c] R_MANt1r subsystem: Transport, Extracellular R_MANt1r equation: man[e] <==> man[c] R_GLCtg subsystem: Transport, Golgi Apparatus R_GLCtg equation: glc-D[c] <==> glc-D[g]

956605
stoichiometry: 1.0
species: 882481
type: SpeciesReference

983422
stoichiometry: 1.0
species: 898864
type: SpeciesReference

922842
stoichiometry: 1.0
species: 894783
type: SpeciesReference

969986
stoichiometry: 1.0
species: 904332
type: SpeciesReference

976004
stoichiometry: 1.0
species: 890650
type: SpeciesReference

910089
reversible: false
is: ENSPTRG00000019514.5
reactant: 992620
product: 992644
type: Reaction
fast: false
notes: R_ACHEe subsystem: Glycerophospholipid Metabolism R_ACHEe equation: [e] : ach + h2o --> ac + chol + h
product: 992668
reactant: 992632
product: 992656
is: http://identifiers.org/ec-code/3.1.1.7
name: Acetylcholinesterase

935337
stoichiometry: 3.0
species: 897888
type: SpeciesReference

903162
reactant: 929588
fast: false
name: thymidine phosphorylase
reactant: 929601
product: 929625
is: http://identifiers.org/ec-code/2.4.2.4
product: 929613
is: ENSPTRG00000014547.3
type: Reaction
notes: R_TMDPP subsystem: Pyrimidine Catabolism R_TMDPP equation: [c] : pi + thymd <==> 2dr1p + thym
reversible: true

900004
fast: false
product: 906762
reactant: 906725
product: 906750
is: ENSPTRG00000020346.3
type: Reaction
reversible: true
notes: R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal
name: retinol dehydrogenase (all-trans,NADPH)
reactant: 906713
product: 906738
is: http://identifiers.org/ec-code/1.1.1.105

001051
stoichiometry: 1.0
species: 880317
type: SpeciesReference

979992
stoichiometry: 1.0
species: 889334
type: SpeciesReference

950109
stoichiometry: 1.0
species: 899662
type: SpeciesReference

978313
stoichiometry: 1.0
species: 887922
type: SpeciesReference

909954
stoichiometry: 1.0
species: 891591
type: SpeciesReference

909405
type: Reaction
product: 985149
reactant: 985124
product: 985161
reactant: 985136
is: http://identifiers.org/ec-code/3.2.1.20
reactant: 985112
reversible: false
notes: R_MALT subsystem: Starch and Sucrose Metabolism R_MALT equation: [c] : h2o + malt --> (2) glc-D R_MLTG1 subsystem: Starch and Sucrose Metabolism R_MLTG1 equation: [c] : h2o + malttr --> glc-D + malt
fast: false
is: ENSPTRG00000006973.3

914390
stoichiometry: 2.0
species: 884270
type: SpeciesReference

913749
stoichiometry: 2.0
species: 887339
type: SpeciesReference

892001
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: hexacosanoate (n-C26:0)_C26H51O2
type: Species

978581
stoichiometry: 1.0
species: 898864
type: SpeciesReference

957596
stoichiometry: 1.0
species: 878000
type: SpeciesReference

927368
stoichiometry: 1.0
species: 881776
type: SpeciesReference

966551
stoichiometry: 1.0
species: 878859
type: SpeciesReference

902055
fast: false
reactant: 920927
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_FRUt4 subsystem: Transport, Extracellular R_FRUt4 equation: fru[e] + na1[e] <==> fru[c] + na1[c] R_MANt4 subsystem: Transport, Extracellular R_MANt4 equation: man[e] + na1[e] <==> man[c] + na1[c] R_GALt4 subsystem: Transport, Extracellular R_GALt4 equation: gal[e] + na1[e] <==> gal[c] + na1[c]
type: Reaction
reactant: 920903
reactant: 920939
is: ENSPTRG00000008861.4
reversible: true
reactant: 920915
product: 920999
is: ENSPTRG00000000716.4
product: 920975
product: 920951
product: 920987
product: 920963
reactant: 920891

009091
stoichiometry: 1.0
species: 893151
type: SpeciesReference

902512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S
type: Species

925200
stoichiometry: 1.0
species: 889851
type: SpeciesReference

960377
stoichiometry: 4.0
species: 891591
type: SpeciesReference

906102
notes: R_P4507A1r subsystem: Bile Acid Biosynthesis R_P4507A1r equation: [r] : chsterol + h + nadph + o2 --> h2o + nadp + xol7a
reactant: 955304
reversible: false
fast: false
reactant: 955280
reactant: 955292
type: Reaction
name: cytochrome P450, family 7, subfamily A, polypeptide 1
product: 955328
is: ENSPTRG00000020275.1
product: 955340
reactant: 955316
is: http://identifiers.org/ec-code/1.14.13.17
product: 955352

901922
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: stearidonyl coenzyme A_C39H58N7O17P3S
type: Species

001701
stoichiometry: 1.0
species: 892449
type: SpeciesReference

973759
stoichiometry: 1.0
species: 895785
type: SpeciesReference

966987
stoichiometry: 1.0
species: 893006
type: SpeciesReference

883289
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cervonyl carnitine_C29H45NO4
type: Species

973109
stoichiometry: 1.0
species: 893478
type: SpeciesReference

008147
stoichiometry: 1.0
species: 882334
type: SpeciesReference

975774
stoichiometry: 1.0
species: 898816
type: SpeciesReference

934233
stoichiometry: 4.0
species: 891531
type: SpeciesReference

921265
stoichiometry: 2.0
species: 884427
type: SpeciesReference

933418
stoichiometry: 1.0
species: 899530
type: SpeciesReference

989642
stoichiometry: 1.0
species: 889651
type: SpeciesReference

900002
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Pregnenolone_C21H32O2
type: Species

955968
stoichiometry: 1.5
species: 897261
type: SpeciesReference

988265
stoichiometry: 1.0
species: 885550
type: SpeciesReference

982253
stoichiometry: 1.0
species: 897552
type: SpeciesReference

902511
reactant: 924763
is: http://identifiers.org/ec-code/2.6.1.16
is: ENSPTRG00000017635.4
product: 924788
notes: R_GF6PTA subsystem: Aminosugar Metabolism R_GF6PTA equation: [c] : f6p + gln-L --> gam6p + glu-L
product: 924776
reactant: 924751
name: glutamine-fructose-6-phosphate transaminase
fast: false
is: ENSPTRG00000024129.3
reversible: false
type: Reaction

990565
stoichiometry: 1.0
species: 891591
type: SpeciesReference

902054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Succinic semialdehyde_C4H5O3
type: Species

919680
stoichiometry: 1.0
species: 886576
type: SpeciesReference

888986
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)3 (Cer)1_C90H155N4O54FULLRCO
type: Species

963042
stoichiometry: 8.0
species: 890020
type: SpeciesReference

930967
stoichiometry: 1.0
species: 897972
type: SpeciesReference

944339
stoichiometry: 3.0
species: 891616
type: SpeciesReference

906319
product: 958357
reversible: false
name: adenylosuccinate synthase
reactant: 958309
product: 958321
is: ENSPTRG00000006773.4
reactant: 958297
reactant: 958284
notes: R_ADSS subsystem: Nucleotides R_ADSS equation: [c] : asp-L + gtp + imp --> dcamp + gdp + (2) h + pi
type: Reaction
fast: false
product: 958345
product: 958333
is: ENSPTRG00000002178.3
is: http://identifiers.org/ec-code/6.3.4.4

906559
type: Reaction
product: 960172
reversible: false
is: ENSPTRG00000016544.2
name: L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
is: http://identifiers.org/ec-code/1.13.11.11
reactant: 960148
reactant: 960160
fast: false
notes: R_TRPO2 subsystem: Tryptophan metabolism R_TRPO2 equation: [c] : o2 + trp-L --> Lfmkynr

945700
stoichiometry: 1.0
species: 901426
type: SpeciesReference

925524
stoichiometry: 4.0
species: 889154
type: SpeciesReference

981856
stoichiometry: 2.0
species: 897516
type: SpeciesReference

932451
stoichiometry: 1.0
species: 896655
type: SpeciesReference

996073
stoichiometry: 1.0
species: 884307
type: SpeciesReference

980499
stoichiometry: 1.0
species: 880486
type: SpeciesReference

939558
stoichiometry: 1.0
species: 896306
type: SpeciesReference

970070
stoichiometry: 1.0
species: 897648
type: SpeciesReference

940199
stoichiometry: 1.0
species: 887594
type: SpeciesReference

977238
stoichiometry: 1.0
species: 894579
type: SpeciesReference

935059
stoichiometry: 1.0
species: 890686
type: SpeciesReference

876548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22
type: Species

976502
stoichiometry: 1.0
species: 898164
type: SpeciesReference

923315
stoichiometry: 6.0
species: 891483
type: SpeciesReference

954023
stoichiometry: 2.0
species: 891531
type: SpeciesReference

909957
type: Reaction
product: 991376
name: Phosphoenolpyruvate carboxykinase (GTP)
fast: false
product: 991364
is: http://identifiers.org/ec-code/4.1.1.32
product: 991352
reactant: 991328
notes: R_PEPCK subsystem: Glycolysis/Gluconeogenesis R_PEPCK equation: [c] : gtp + oaa --> co2 + gdp + pep
is: ENSPTRG00000013664.2
reactant: 991340
reversible: false

890434
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO
type: Species

975123
stoichiometry: 1.0
species: 883386
type: SpeciesReference

892365
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 13_C55H83N3O61S5
type: Species

926416
stoichiometry: 1.0
species: 882805
type: SpeciesReference

923460
stoichiometry: 7.0
species: 891411
type: SpeciesReference

928444
stoichiometry: 11.0
species: 890083
type: SpeciesReference

965366
stoichiometry: 1.0
species: 884548
type: SpeciesReference

990160
stoichiometry: 32.0
species: 891616
type: SpeciesReference

919160
stoichiometry: 4.0
species: 882781
type: SpeciesReference

990015
stoichiometry: 1.0
species: 880631
type: SpeciesReference

952128
stoichiometry: 2.0
species: 891640
type: SpeciesReference

965174
stoichiometry: 2.0
species: 891591
type: SpeciesReference

947375
stoichiometry: 1.0
species: 883143
type: SpeciesReference

942981
stoichiometry: 1.0
species: 891640
type: SpeciesReference

971166
stoichiometry: 12.0
species: 891531
type: SpeciesReference

997160
stoichiometry: 1.0
species: 900885
type: SpeciesReference

881644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: S-Adenosyl-L-homocysteine_C14H20N6O5S
type: Species

908146
stoichiometry: 1.0
species: 898575
type: SpeciesReference

921482
stoichiometry: 6.0
species: 891628
type: SpeciesReference

924269
stoichiometry: 1.0
species: 897261
type: SpeciesReference

905612
stoichiometry: 3.0
species: 899542
type: SpeciesReference

951296
stoichiometry: 16.0
species: 890167
type: SpeciesReference

904237
reactant: 938825
is: ENSPTRG00000013030.3
is: ENSPTRG00000015807.4
is: ENSPTRG00000002769.5
is: ENSPTRG00000017404.3
is: ENSPTRG00000004730.1
reactant: 938813
reversible: false
name: _3',5'-cyclic-nucleotide phosphodiesterase
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h
product: 938849
type: Reaction
product: 938837
fast: false
is: http://identifiers.org/ec-code/3.1.4.17

994334
stoichiometry: 1.0
species: 895944
type: SpeciesReference

907701
stoichiometry: 3.0
species: 898272
type: SpeciesReference

978013
stoichiometry: 1.0
species: 902980
type: SpeciesReference

886648
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Dehydroepiandrosterone sulfate_C19H27O5S
type: Species

881390
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: ADPribose_C15H21N5O14P2
type: Species

880051
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S
type: Species

917938
stoichiometry: 4.0
species: 882781
type: SpeciesReference

914970
stoichiometry: 1.0
species: 887241
type: SpeciesReference

890916
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: GMP_C10H12N5O8P
type: Species

000326
stoichiometry: 18.0
species: 882781
type: SpeciesReference

935879
stoichiometry: 1.0
species: 898358
type: SpeciesReference

889058
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Lacto-N-fucopentaosyl III ceramide_C50H89N2O26FULLRCO
type: Species

963261
stoichiometry: 1.0
species: 903488
type: SpeciesReference

883699
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Choline_C5H14NO
type: Species

948306
stoichiometry: 1.0
species: 902270
type: SpeciesReference

890650
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Glycerol_C3H8O3
type: Species

916296
stoichiometry: 1.0
species: 882925
type: SpeciesReference

899494
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: phytanic acid_C20H39O2
type: Species

949977
stoichiometry: 1.0
species: 895641
type: SpeciesReference

912096
fast: false
product: 010615
name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
reactant: 010589
notes: R_PHETHPTOX2 subsystem: Tyr, Phe, Trp Biosynthesis R_PHETHPTOX2 equation: [c] : o2 + phe-L + thbpt --> thbpt4acam + tyr-L
product: 010628
reactant: 010576
is: http://identifiers.org/ec-code/1.14.16.1
reversible: false
reactant: 010602
is: ENSPTRG00000005364.3
type: Reaction

911186
stoichiometry: 3.0
species: 899021
type: SpeciesReference

906774
stoichiometry: 1.0
species: 899530
type: SpeciesReference

978750
stoichiometry: 1.0
species: 891483
type: SpeciesReference

939333
stoichiometry: 1.0
species: 878531
type: SpeciesReference

941118
stoichiometry: 1.0
species: 898852
type: SpeciesReference

933310
stoichiometry: 1.0
species: 878325
type: SpeciesReference

911291
product: 001881
reactant: 001869
reversible: true
is: ENSPTRG00000022036.3
notes: R_TRIODTHYt2 subsystem: Transport, Extracellular R_TRIODTHYt2 equation: triodthy[e] <==> triodthy[c] R_THYOXt2 subsystem: Transport, Extracellular R_THYOXt2 equation: thyox-L[e] <==> thyox-L[c]
product: 001893
reactant: 001857
type: Reaction
fast: false

900763
is: ENSPTRG00000016118.2
reversible: false
product: 911150
reactant: 911090
product: 911126
fast: false
notes: R_ESTSULT subsystem: Steroid Metabolism R_ESTSULT equation: [c] : estrone + paps --> estrones + h + pap R_DHEASULT subsystem: Steroid Metabolism R_DHEASULT equation: [c] : dhea + paps --> dheas + h + pap
product: 911114
reactant: 911078
is: http://identifiers.org/ec-code/2.8.2.4
type: Reaction
reactant: 911102
product: 911138
is: http://identifiers.org/ec-code/2.8.2.2

911429
stoichiometry: 3.0
species: 899214
type: SpeciesReference

945061
stoichiometry: 1.0
species: 884391
type: SpeciesReference

962138
stoichiometry: 1.0
species: 903596
type: SpeciesReference

943913
stoichiometry: 1.0
species: 884427
type: SpeciesReference

923025
stoichiometry: 1.0
species: 894663
type: SpeciesReference

958803
stoichiometry: 2.0
species: 891664
type: SpeciesReference

002993
stoichiometry: 1.0
species: 898442
type: SpeciesReference

972699
stoichiometry: 1.0
species: 893864
type: SpeciesReference

983856
stoichiometry: 1.0
species: 886829
type: SpeciesReference

981179
stoichiometry: 1.0
species: 898563
type: SpeciesReference

963795
stoichiometry: 1.0
species: 881282
type: SpeciesReference

879583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: protein-linked asparagine residue (N-glycosylation site)_XH
type: Species

991388
stoichiometry: 1.0
species: 886166
type: SpeciesReference

989991
stoichiometry: 1.0
species: 889742
type: SpeciesReference

942534
stoichiometry: 1.0
species: 878072
type: SpeciesReference

946894
stoichiometry: 1.0
species: 901117
type: SpeciesReference

901138
product: 914354
reactant: 914318
reactant: 914306
reversible: false
name: CTP synthase (NH3)
is: http://identifiers.org/ec-code/6.3.4.2
is: ENSPTRG00000019805.5
fast: false
product: 914342
product: 914378
product: 914366
type: Reaction
notes: R_CTPS1 subsystem: Nucleotides R_CTPS1 equation: [c] : atp + nh4 + utp --> adp + ctp + (2) h + pi
reactant: 914330

957234
stoichiometry: 1.0
species: 900472
type: SpeciesReference

005032
stoichiometry: 1.0
species: 891832
type: SpeciesReference

997607
stoichiometry: 1.0
species: 884391
type: SpeciesReference

010019
stoichiometry: 1.0
species: 880523
type: SpeciesReference

899190
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2
type: Species

928962
stoichiometry: 1.0
species: 890167
type: SpeciesReference

941468
stoichiometry: 1.0
species: 889226
type: SpeciesReference

906775
product: 961691
is: ENSPTRG00000016456.2
is: ENSPTRG00000021867.4
type: Reaction
is: ENSPTRG00000010225.4
reactant: 961643
product: 961703
is: ENSPTRG00000005598.3
reactant: 961655
product: 961667
notes: R_LYSMTF3n subsystem: Lysine Metabolism R_LYSMTF3n equation: [n] : Ndmelys + amet --> Ntmelys + ahcys R_LYSMTF1n subsystem: Lysine Metabolism R_LYSMTF1n equation: [n] : amet + peplys --> Nmelys + ahcys R_LYSMTF2n subsystem: Lysine Metabolism R_LYSMTF2n equation: [n] : Nmelys + amet --> Ndmelys + ahcys
reactant: 961631
reversible: false
is: ENSPTRG00000019892.4
is: http://identifiers.org/ec-code/2.1.1.43
product: 961679
fast: false
is: ENSPTRG00000005873.4
reactant: 961619
is: ENSPTRG00000003804.4
is: ENSPTRG00000021607.5
is: ENSPTRG00000002313.5

912807
stoichiometry: 1.0
species: 888176
type: SpeciesReference

938076
stoichiometry: 1.0
species: 898418
type: SpeciesReference

918097
stoichiometry: 1.0
species: 887253
type: SpeciesReference

905043
is: ENSPTRG00000013699.5
notes: R_PGESr subsystem: Eicosanoid Metabolism R_PGESr equation: [r] : prostgh2 <==> prostge2
name: Prostaglandin E synthase
is: ENSPTRG00000021411.5
fast: false
product: 945169
reversible: true
reactant: 945157
is: http://identifiers.org/ec-code/5.3.99.3
type: Reaction

908886
stoichiometry: 1.0
species: 890458
type: SpeciesReference

918881
stoichiometry: 2.0
species: 897660
type: SpeciesReference

895593
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: gamma-linolenic acid_C18H29O2
type: Species

972154
stoichiometry: 24.0
species: 903488
type: SpeciesReference

001123
stoichiometry: 2.0
species: 899795
type: SpeciesReference

916547
stoichiometry: 1.0
species: 902402
type: SpeciesReference

987964
stoichiometry: 1.0
species: 897359
type: SpeciesReference

896958
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _5,10-Methylenetetrahydrofolate_C20H21N7O6
type: Species

917370
stoichiometry: 2.0
species: 891591
type: SpeciesReference

919366
stoichiometry: 2.0
species: 881764
type: SpeciesReference

922625
stoichiometry: 1.0
species: 890362
type: SpeciesReference

916272
stoichiometry: 1.0
species: 888370
type: SpeciesReference

988808
stoichiometry: 1.0
species: 890216
type: SpeciesReference

880824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GlcNAc-Gal globoside (homo sapiens)_C58H102N3O32FULLRCO
type: Species

936315
stoichiometry: 3.0
species: 899021
type: SpeciesReference

917225
stoichiometry: 1.0
species: 878325
type: SpeciesReference

954665
stoichiometry: 1.0
species: 899518
type: SpeciesReference

905042
stoichiometry: 2.0
species: 880414
type: SpeciesReference

966335
stoichiometry: 1.0
species: 896619
type: SpeciesReference

941312
stoichiometry: 3.0
species: 899530
type: SpeciesReference

904236
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _24-Hydroxycholesterol_C27H46O2
type: Species

898961
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Palmitoyl-ACP (n-C16:0ACP)_C27H51N2O8PRS
type: Species

909621
reversible: false
reactant: 987398
reactant: 987338
product: 987458
product: 987542
reactant: 987374
reactant: 987422
product: 987446
product: 987530
reactant: 987386
reactant: 987326
product: 987518
product: 987494
product: 987506
product: 987482
product: 987470
reactant: 987350
fast: false
reactant: 987314
reactant: 987434
product: 987554
reactant: 987362
type: Reaction
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
is: http://identifiers.org/ec-code/3.2.1.113
reactant: 987410
is: ENSPTRG00000024134.4

952660
stoichiometry: 2.0
species: 899530
type: SpeciesReference

969172
stoichiometry: 1.0
species: 891796
type: SpeciesReference

908692
stoichiometry: 1.0
species: 894771
type: SpeciesReference

886227
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: all trans Decaprenyl diphosphate_C50H81O7P2
type: Species

003944
stoichiometry: 17.0
species: 880644
type: SpeciesReference

930628
stoichiometry: 1.0
species: 883687
type: SpeciesReference

898272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Octanoyl-CoA (n-C8:0CoA)_C29H46N7O17P3S
type: Species

907702
is: ENSPTRG00000017022.1
fast: false
notes: R_BHMT subsystem: Glycine, Serine, and Threonine Metabolism R_BHMT equation: [c] : glyb + hcys-L --> dmgly + met-L
name: betaine-homocysteine S-methyltransferase
reactant: 969184
reactant: 969172
product: 969196
product: 969208
reversible: false
is: ENSPTRG00000017023.4
type: Reaction
is: http://identifiers.org/ec-code/2.1.1.5

900401
is: http://identifiers.org/ec-code/1.1.1.37
reactant: 908595
reactant: 908619
product: 908656
product: 908668
product: 908632
reactant: 908607
reversible: true
type: Reaction
notes: R_MDHm subsystem: Citric Acid Cycle R_MDHm equation: [m] : mal-L + nad <==> h + nadh + oaa R_SLDxm subsystem: Cysteine Metabolism R_SLDxm equation: [m] : nad + sl-L <==> 3spyr + h + nadh
is: ENSPTRG00000012580.4
is: http://identifiers.org/ec-code/1.1.1.272
product: 908644
fast: false

999632
stoichiometry: 1.0
species: 904103
type: SpeciesReference

942086
stoichiometry: 1.0
species: 902572
type: SpeciesReference

939005
stoichiometry: 4.0
species: 891748
type: SpeciesReference

908888
reactant: 981868
fast: false
reversible: false
is: ENSPTRG00000004055.2
is: ENSPTRG00000018236.5
notes: R_Htm subsystem: Transport, Mitochondrial R_Htm equation: h[c] --> h[m]
is: ENSPTRG00000016463.3
type: Reaction
name: Uncoupling protein
product: 981880
is: ENSPTRG00000004056.4
is: ENSPTRG00000022268.4

905368
product: 947713
product: 947737
product: 947701
reactant: 947521
product: 947893
product: 947725
reactant: 947545
reactant: 947461
product: 947821
is: ENSPTRG00000011967.3
reactant: 947617
product: 947905
reactant: 947593
reactant: 947424
product: 947665
fast: false
product: 947773
reactant: 947533
product: 947809
product: 947689
reactant: 947557
product: 947749
product: 947653
product: 947761
product: 947677
reactant: 947473
reactant: 947437
reactant: 947605
reactant: 947497
product: 947845
reactant: 947629
product: 947869
product: 947833
is: http://identifiers.org/ec-code/2.4.1.149
product: 947857
reactant: 947399
type: Reaction
reactant: 947641
product: 947797
reactant: 947569
reactant: 947509
product: 947785
reactant: 947581
reactant: 947412
reactant: 947485
reactant: 947449
notes: R_B3GNT11g subsystem: Blood Group Biosynthesis R_B3GNT11g equation: [g] : gal14acglcgalgluside_hs + uacgam --> acglcgal14acglcgalgluside_hs + h + udp R_AG13T6g subsystem: Keratan sulfate biosynthesis R_AG13T6g equation: [g] : ksi_pre6 + uacgam --> h + ksi_pre7 + udp R_AG13T17g subsystem: Keratan sulfate biosynthesis R_AG13T17g equation: [g] : ksii_core4_pre4 + uacgam --> h + ksii_core4_pre5 + udp R_B3GNT12g subsystem: Blood Group Biosynthesis R_B3GNT12g equation: [g] : galacglcgal14acglcgalgluside_hs + uacgam --> acglc13galacglcgal14acglcgalgluside_hs + h + udp R_AG13T2g subsystem: Keratan sulfate biosynthesis R_AG13T2g equation: [g] : ksii_core2_pre4 + uacgam --> h + ksii_core2_pre5 + udp R_AG13T5g subsystem: Keratan sulfate biosynthesis R_AG13T5g equation: [g] : ksi_pre3 + uacgam --> h + ksi_pre4 + udp R_AG13T8g subsystem: Keratan sulfate biosynthesis R_AG13T8g equation: [g] : ksi_pre12 + uacgam --> h + ksi_pre13 + udp R_AG13T12g subsystem: Keratan sulfate biosynthesis R_AG13T12g equation: [g] : ksi_pre24 + uacgam --> h + ksi_pre25 + udp R_AG13T1g subsystem: Keratan sulfate biosynthesis R_AG13T1g equation: [g] : ksii_core2_pre2 + uacgam --> h + ksii_core2_pre3 + udp R_AG13T10g subsystem: Keratan sulfate biosynthesis R_AG13T10g equation: [g] : ksi_pre18 + uacgam --> h + ksi_pre19 + udp R_AG13T14g subsystem: Keratan sulfate biosynthesis R_AG13T14g equation: [g] : ksi_pre30 + uacgam --> h + ksi_pre31 + udp R_AG13T13g subsystem: Keratan sulfate biosynthesis R_AG13T13g equation: [g] : ksi_pre27 + uacgam --> h + ksi_pre28 + udp R_AG13T9g subsystem: Keratan sulfate biosynthesis R_AG13T9g equation: [g] : ksi_pre15 + uacgam --> h + ksi_pre16 + udp R_AG13T15g subsystem: Keratan sulfate biosynthesis R_AG13T15g equation: [g] : ksi_pre33 + uacgam --> h + ksi_pre34 + udp R_AG13T4g subsystem: Keratan sulfate biosynthesis R_AG13T4g equation: [g] : ksi_pre1 + uacgam --> h + ksi_pre2 + udp R_AG13T11g subsystem: Keratan sulfate biosynthesis R_AG13T11g equation: [g] : ksi_pre21 + uac…
reversible: false
product: 947881

877914
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3-Methylglutaconyl-CoA_C27H37N7O19P3S
type: Species

914826
stoichiometry: 1.0
species: 897321
type: SpeciesReference

996678
stoichiometry: 1.0
species: 881837
type: SpeciesReference

947845
stoichiometry: 1.0
species: 894032
type: SpeciesReference

004137
stoichiometry: 2.0
species: 893828
type: SpeciesReference

003186
stoichiometry: 1.0
species: 895629
type: SpeciesReference

988482
stoichiometry: 1.0
species: 888635
type: SpeciesReference

880499
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Acetyl-CoA_C23H34N7O17P3S
type: Species

008585
stoichiometry: 1.0
species: 888466
type: SpeciesReference

964898
stoichiometry: 1.0
species: 878024
type: SpeciesReference

943764
stoichiometry: 1.0
species: 896378
type: SpeciesReference

009695
stoichiometry: 2.0
species: 891483
type: SpeciesReference

937677
stoichiometry: 1.0
species: 884355
type: SpeciesReference

879366
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _6-phospho-D-glucono-1,5-lactone_C6H9O9P
type: Species

902475
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: tetracosapentaenoyl carnitine_C31H51NO4
type: Species

966769
stoichiometry: 1.0
species: 880535
type: SpeciesReference

888575
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Ferricytochrome c_C42H54FeN8O6S2
type: Species

958717
stoichiometry: 2.0
species: 891604
type: SpeciesReference

916694
stoichiometry: 1.0
species: 902548
type: SpeciesReference

928228
stoichiometry: 4.0
species: 903076
type: SpeciesReference

996895
stoichiometry: 2.0
species: 889996
type: SpeciesReference

900400
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Prostaglandin H2_C20H31O5
type: Species

884862
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 2_C37H55NO38S2
type: Species

007930
stoichiometry: 1.0
species: 888370
type: SpeciesReference

006553
stoichiometry: 1.0
species: 903233
type: SpeciesReference

986687
stoichiometry: 1.0
species: 901438
type: SpeciesReference

985902
stoichiometry: 1.5
species: 898092
type: SpeciesReference

915440
stoichiometry: 1.0
species: 895000
type: SpeciesReference

908472
stoichiometry: 3.0
species: 882805
type: SpeciesReference

943017
stoichiometry: 1.0
species: 897443
type: SpeciesReference

971876
stoichiometry: 1.0
species: 890180
type: SpeciesReference

979413
stoichiometry: 1.0
species: 887278
type: SpeciesReference

901705
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

967822
stoichiometry: 1.0
species: 903909
type: SpeciesReference

986289
stoichiometry: 1.0
species: 894963
type: SpeciesReference

975558
stoichiometry: 1.0
species: 886793
type: SpeciesReference

901585
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Sulfate_O4S
type: Species

954399
stoichiometry: 2.0
species: 888902
type: SpeciesReference

937919
stoichiometry: 1.0
species: 900872
type: SpeciesReference

886081
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Deoxycytidine_C9H13N3O4
type: Species

965584
stoichiometry: 1.0
species: 877372
type: SpeciesReference

889382
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GA1 (homo sapiens)_C44H79N2O22FULLRCO
type: Species

899614
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Phosphate_HO4P
type: Species

891917
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
type: Species

932030
stoichiometry: 1.0
species: 891748
type: SpeciesReference

010786
stoichiometry: 1.0
species: 891591
type: SpeciesReference

894346
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 3_C93H152N6O67X
type: Species

963372
stoichiometry: 2.0
species: 903728
type: SpeciesReference

914076
stoichiometry: 1.0
species: 878884
type: SpeciesReference

895725
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Gal-Xyl-L-Ser (protein)_C11H19O9X
type: Species

892583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 6_C67H98N4O83S9
type: Species

904994
stoichiometry: 1.0
species: 889827
type: SpeciesReference

925911
stoichiometry: 1.0
species: 879535
type: SpeciesReference

969547
stoichiometry: 5.0
species: 903560
type: SpeciesReference

007786
stoichiometry: 1.0
species: 891591
type: SpeciesReference

897636
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Ammonium_H4N
type: Species

902619
reactant: 925428
is: http://identifiers.org/ec-code/3.2.1.33
notes: R_GLDBRAN subsystem: Starch and Sucrose Metabolism R_GLDBRAN equation: [c] : dxtrn + h2o --> glc-D + glygn3
reversible: false
fast: false
name: glycogen debranching enzyme
reactant: 925440
type: Reaction
is: ENSPTRG00000000997.5
product: 925464
product: 925452

909626
stoichiometry: 1.0
species: 897419
type: SpeciesReference

971719
stoichiometry: 1.0
species: 882733
type: SpeciesReference

959368
stoichiometry: 1.0
species: 894963
type: SpeciesReference

933637
stoichiometry: 1.0
species: 889286
type: SpeciesReference

901706
type: Reaction
reactant: 917454
notes: R_NNATr subsystem: NAD Metabolism R_NNATr equation: [c] : atp + h + nicrnt <==> dnad + ppi R_NMNATr subsystem: NAD Metabolism R_NMNATr equation: [c] : atp + h + nmn <==> nad + ppi
product: 917490
reversible: true
is: http://identifiers.org/ec-code/2.7.7.1
fast: false
reactant: 917478
reactant: 917466
reactant: 917442
product: 917514
is: http://identifiers.org/ec-code/2.7.7.18
product: 917502
is: ENSPTRG00000001763.3

958501
stoichiometry: 1.0
species: 890868
type: SpeciesReference

987205
stoichiometry: 2.0
species: 891483
type: SpeciesReference

960944
stoichiometry: 1.0
species: 893223
type: SpeciesReference

912953
stoichiometry: 1.0
species: 900026
type: SpeciesReference

914644
stoichiometry: 1.0
species: 890964
type: SpeciesReference

988012
stoichiometry: 2.0
species: 885490
type: SpeciesReference

889502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO
type: Species

998838
stoichiometry: 1.0
species: 876789
type: SpeciesReference

900979
name: glutathione peroxidase, mitochondria
reversible: true
fast: false
reactant: 912771
notes: R_GTHPm subsystem: Glutathione Metabolism R_GTHPm equation: [m] : (2) gthrd + h2o2 <==> gthox + (2) h2o
is: ENSPTRG00000002992.5
type: Reaction
product: 912795
reactant: 912759
is: http://identifiers.org/ec-code/1.11.1.9
product: 912783

882322
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Apocarboxylase (Lys residue)_C6H13N2OX
type: Species

992741
stoichiometry: 1.0
species: 878763
type: SpeciesReference

933977
stoichiometry: 2.0
species: 899578
type: SpeciesReference

952345
stoichiometry: 1.0
species: 898394
type: SpeciesReference

008863
stoichiometry: 2.0
species: 897443
type: SpeciesReference

908696
notes: R_ACP1_LPAREN_FMN_RPAREN_ subsystem: Riboflavin Metabolism R_ACP1_LPAREN_FMN_RPAREN_ equation: [c] : fmn + h2o --> pi + ribflv
is: ENSPTRG00000011605.4
product: 980294
type: Reaction
reversible: false
product: 980282
reactant: 980258
fast: false
is: http://identifiers.org/ec-code/3.1.3.2
reactant: 980270
name: acid phosphatase (FMN)

885804
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: dAMP_C10H12N5O6P
type: Species

944557
stoichiometry: 1.0
species: 896088
type: SpeciesReference

917646
stoichiometry: 1.0
species: 898020
type: SpeciesReference

959472
stoichiometry: 1.0
species: 891531
type: SpeciesReference

884778
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cervonic acid, C22:6 n-3_C22H31O2
type: Species

009549
stoichiometry: 1.0
species: 891519
type: SpeciesReference

934902
stoichiometry: 1.0
species: 895024
type: SpeciesReference

879210
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

900764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Ubiquinone-10_C59H90O4
type: Species

910786
type: Reaction
product: 996738
fast: false
reactant: 996690
notes: R_2OXOADPTm subsystem: Tryptophan metabolism R_2OXOADPTm equation: _2oxoadp[c] + akg[m] <==> 2oxoadp[m] + akg[c] R_2AMADPTm subsystem: Lysine Metabolism R_2AMADPTm equation: L2aadp[c] + akg[m] <==> L2aadp[m] + akg[c]
reactant: 996702
product: 996750
is: ENSPTRG00000006283.3
reversible: true
product: 996726
reactant: 996714

970746
stoichiometry: 23.0
species: 891591
type: SpeciesReference

960233
stoichiometry: 1.0
species: 880244
type: SpeciesReference

989256
stoichiometry: 1.0
species: 888273
type: SpeciesReference

922505
stoichiometry: 1.0
species: 892085
type: SpeciesReference

996339
stoichiometry: 2.0
species: 897443
type: SpeciesReference

906211
reactant: 956485
product: 956775
reactant: 956304
product: 956641
product: 956811
reactant: 956208
notes: R_RTOTALCRNt subsystem: Carnitine shuttle R_RTOTALCRNt equation: Rtotalcrn[c] --> Rtotalcrn[m] R_LNLNCGCRNt subsystem: Carnitine shuttle R_LNLNCGCRNt equation: lnlncgcrn[c] --> lnlncgcrn[m] R_ACRNtm subsystem: Transport, Mitochondrial R_ACRNtm equation: acrn[c] --> acrn[m] R_LNLNCACRNt subsystem: Carnitine shuttle R_LNLNCACRNt equation: lnlncacrn[c] --> lnlncacrn[m] R_DLNLCGCRNt subsystem: Carnitine shuttle R_DLNLCGCRNt equation: dlnlcgcrn[c] --> dlnlcgcrn[m] R_STRDNCCRNt subsystem: Carnitine shuttle R_STRDNCCRNt equation: strdnccrn[c] --> strdnccrn[m] R_CRNtim subsystem: Transport, Mitochondrial R_CRNtim equation: crn[m] --> crn[c] R_TETTET6CRNt subsystem: Carnitine shuttle R_TETTET6CRNt equation: tettet6crn[c] --> tettet6crn[m] R_RTOTAL2CRNt subsystem: Carnitine shuttle R_RTOTAL2CRNt equation: Rtotal2crn[c] --> Rtotal2crn[m] R_DCSPTN1CRNt subsystem: Carnitine shuttle R_DCSPTN1CRNt equation: dcsptn1crn[c] --> dcsptn1crn[m] R_C161CRN2t subsystem: Carnitine shuttle R_C161CRN2t equation: hdd2crn[c] --> hdd2crn[m] R_C181CRNt subsystem: Carnitine shuttle R_C181CRNt equation: odecrn[c] --> odecrn[m] R_EICOSTETCRNt subsystem: Carnitine shuttle R_EICOSTETCRNt equation: eicostetcrn[c] --> eicostetcrn[m] R_TTDCRNt subsystem: Carnitine shuttle R_TTDCRNt equation: ttdcrn[c] --> ttdcrn[m] R_TMNDNCCRNt subsystem: Carnitine shuttle R_TMNDNCCRNt equation: tmndnccrn[c] --> tmndnccrn[m] R_CLPNDCRNt subsystem: Carnitine shuttle R_CLPNDCRNt equation: clpndcrn[c] --> clpndcrn[m] R_LGNCCRNt subsystem: Carnitine shuttle R_LGNCCRNt equation: lgnccrn[c] --> lgnccrn[m] R_VACCCRNt subsystem: Carnitine shuttle R_VACCCRNt equation: vacccrn[c] --> vacccrn[m] R_ADRNCRNt subsystem: Carnitine shuttle R_ADRNCRNt equation: adrncrn[c] --> adrncrn[m] R_NRVNCCRNt subsystem: Carnitine shuttle R_NRVNCCRNt equation: nrvnccrn[c] --> nrvnccrn[m] R_TETPENT6CRNt subsystem: Carnitine shuttle R_TETPENT6CRNt equation: tetpent6crn[c] --> tetpent6crn[m] R_LNELDCCRNt subsystem: Carnitine shuttle R_LNELDCCRNt equati…
product: 956629
reactant: 956569
product: 956593
product: 956739
product: 956847
product: 956653
reactant: 956461
reactant: 956497
product: 956690
product: 956871
product: 956932
product: 956968
product: 956702
reactant: 956521
product: 956678
type: Reaction
product: 956920
reactant: 956545
product: 956714
reactant: 956533
reversible: false
reactant: 956341
reactant: 956557
reactant: 956280
product: 956763
product: 956799
is: ENSPTRG00000014900.2
reactant: 956353
reactant: 956389
reactant: 956292
product: 956835
product: 956981
product: 956859
product: 956751
product: 956823
fast: false
reactant: 956328
product: 956666
product: 956605
reactant: 956220
reactant: 956581
reactant: 956365
reactant: 956437
reactant: 956268
product: 956956
reactant: 956377
reactant: 956449
reactant: 956509
reactant: 956196
reactant: 956316
product: 956907
product: 956895
product: 956787
reactant: 956413
product: 956883
reactant: 956244
reactant: 956401
product: 956617
product: 956944
reactant: 956232
reactant: 956425
reactant: 956256
product: 956726
reactant: 956473

900824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: alpha-D-Ribose 5-phosphate_C5H9O8P
type: Species

996786
stoichiometry: 1.0
species: 891254
type: SpeciesReference

892207
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Homoserine_C4H9NO3
type: Species

005465
stoichiometry: 1.0
species: 888176
type: SpeciesReference

939103
stoichiometry: 1.0
species: 903125
type: SpeciesReference

999928
stoichiometry: 1.0
species: 881258
type: SpeciesReference

977602
stoichiometry: 8.0
species: 891616
type: SpeciesReference

888684
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Formate_CH1O2
type: Species

913181
stoichiometry: 1.0
species: 882613
type: SpeciesReference

948724
stoichiometry: 2.0
species: 884270
type: SpeciesReference

947953
stoichiometry: 1.0
species: 883663
type: SpeciesReference

935613
stoichiometry: 2.0
species: 891652
type: SpeciesReference

902366
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S
type: Species

005839
stoichiometry: 2.0
species: 888623
type: SpeciesReference

986795
stoichiometry: 1.0
species: 887181
type: SpeciesReference

966878
stoichiometry: 1.0
species: 891591
type: SpeciesReference

905909
product: 954023
type: Reaction
fast: false
is: ENSPTRG00000018164.3
is: http://identifiers.org/ec-code/1.14.15.4
product: 954035
reactant: 953999
product: 954011
reactant: 953975
reversible: false
notes: R_P45011B21m subsystem: Steroid Metabolism R_P45011B21m equation: [m] : 11docrtstrn + h + nadph + (2) o2 --> aldstrn + (2) h2o + nadp
name: Steroid 11-beta-hydroxylase
reactant: 953962
reactant: 953987

986579
stoichiometry: 1.0
species: 891591
type: SpeciesReference

010453
stoichiometry: 3.0
species: 891567
type: SpeciesReference

943655
stoichiometry: 1.0
species: 897492
type: SpeciesReference

998260
stoichiometry: 2.0
species: 891483
type: SpeciesReference

936880
stoichiometry: 1.0
species: 881608
type: SpeciesReference

881583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8
type: Species

900556
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: pendtadenoyl carnitine_C22H43NO4
type: Species

928118
stoichiometry: 1.0
species: 894927
type: SpeciesReference

877613
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-3-Amino-isobutanoate_C4H9NO2
type: Species

966106
stoichiometry: 7.92
species: 891640
type: SpeciesReference

955774
stoichiometry: 2.0
species: 897443
type: SpeciesReference

900823
notes: R_LACZe subsystem: Galactose metabolism R_LACZe equation: [e] : h2o + lcts --> gal + glc-D
reactant: 911516
reversible: false
fast: false
type: Reaction
reactant: 911529
is: http://identifiers.org/ec-code/3.2.1.23
name: b-galactosidase, extracellular
product: 911553
product: 911541
is: ENSPTRG00000012497.2

914534
stoichiometry: 1.0
species: 880486
type: SpeciesReference

991509
stoichiometry: 1.0
species: 886166
type: SpeciesReference

976874
stoichiometry: 10.0
species: 885913
type: SpeciesReference

997016
stoichiometry: 1.0
species: 881258
type: SpeciesReference

958609
stoichiometry: 1.0
species: 901633
type: SpeciesReference

896547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Methanol_CH4O1
type: Species

897213
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: ((N-acetyl-D-glucosaminyl)3-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C58H96N5O40X
type: Species

907930
reversible: false
reactant: 971647
notes: R_PMEVKx subsystem: Cholesterol Metabolism R_PMEVKx equation: [x] : 5pmev + atp --> 5dpmev + adp
is: http://identifiers.org/ec-code/2.7.4.2
type: Reaction
product: 971671
reactant: 971659
product: 971683
name: phosphomevalonate kinase
is: ENSPTRG00000001393.4
fast: false

902367
is: ENSPTRG00000029304.1
name: ADP/ATP transporter, mitochondrial
is: ENSPTRG00000016646.3
product: 923799
fast: false
type: Reaction
notes: R_ATPtm subsystem: Transport, Mitochondrial R_ATPtm equation: adp[c] + atp[m] --> adp[m] + atp[c]
reactant: 923787
product: 923811
reversible: false
reactant: 923775

924836
stoichiometry: 1.0
species: 889899
type: SpeciesReference

009995
stoichiometry: 1.0
species: 880486
type: SpeciesReference

994854
stoichiometry: 1.0
species: 897395
type: SpeciesReference

929649
stoichiometry: 1.0
species: 904272
type: SpeciesReference

993477
stoichiometry: 1.0
species: 891110
type: SpeciesReference

931088
stoichiometry: 1.0
species: 883276
type: SpeciesReference

984050
stoichiometry: 5.0
species: 901573
type: SpeciesReference

964740
stoichiometry: 3.0
species: 893418
type: SpeciesReference

887727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phosphorylase-limit dextrin (glycogenin-1,6{4[1,4-Glc], 4[1,4-Glc]})_C48H81O41X
type: Species

979522
stoichiometry: 1.0
species: 898744
type: SpeciesReference

915331
stoichiometry: 1.0
species: 879017
type: SpeciesReference

891050
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GQ1c (homo sapiens)_C88H143N6O54FULLRCO
type: Species

876971
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1-Methylnicotinamide_C7H9N2O
type: Species

888140
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: estrone glucuronide_C24H30O8
type: Species

008475
stoichiometry: 1.0
species: 891591
type: SpeciesReference

926779
stoichiometry: 1.0
species: 884693
type: SpeciesReference

975498
stoichiometry: 1.0
species: 877662
type: SpeciesReference

968666
stoichiometry: 1.0
species: 898539
type: SpeciesReference

904392
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _7alpha,12alpha-Dihydroxycholest-4-en-3-one_C27H44O3
type: Species

970636
stoichiometry: 1.0
species: 890686
type: SpeciesReference

949545
stoichiometry: 1.0
species: 881294
type: SpeciesReference

996449
stoichiometry: 1.0
species: 891616
type: SpeciesReference

960835
stoichiometry: 1.0
species: 896257
type: SpeciesReference

895617
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: gamma-linolenoyl-CoA_C39H60N7O17P3S
type: Species

969438
stoichiometry: 1.0
species: 882781
type: SpeciesReference

986131
stoichiometry: 2.0
species: 880414
type: SpeciesReference

010678
stoichiometry: 4.0
species: 891591
type: SpeciesReference

953290
stoichiometry: 2.0
species: 891591
type: SpeciesReference

903860
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Urocanate_C6H5N2O2
type: Species

904538
product: 941131
product: 941155
reactant: 941070
reactant: 941082
product: 941118
is: ENSPTRG00000002719.4
reactant: 941094
notes: R_PI345P3Pn subsystem: Inositol Phosphate Metabolism R_PI345P3Pn equation: [n] : h2o + pail345p_hs --> pail45p_hs + pi R_PI345P3P subsystem: Inositol Phosphate Metabolism R_PI345P3P equation: [c] : h2o + pail345p_hs --> pail45p_hs + pi
reactant: 941106
product: 941143
reversible: false
fast: false
type: Reaction
is: http://identifiers.org/ec-code/3.1.3.67

885128
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 3_C37H54NO41S3
type: Species

952455
stoichiometry: 2.0
species: 889418
type: SpeciesReference

008755
stoichiometry: 1.0
species: 884572
type: SpeciesReference

884109
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: clupanodonic acid_C22H33O2
type: Species

949821
stoichiometry: 1.0
species: 882433
type: SpeciesReference

989365
stoichiometry: 1.0
species: 880414
type: SpeciesReference

971419
stoichiometry: 1.0
species: 894987
type: SpeciesReference

933745
stoichiometry: 1.0
species: 901645
type: SpeciesReference

984700
stoichiometry: 1.0
species: 897636
type: SpeciesReference

937521
stoichiometry: 1.0
species: 879727
type: SpeciesReference

889612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)6 (Glc)1 (GlcNAc)3 (LFuc)2 (Cer)1_C96H165N4O60FULLRCO
type: Species

886360
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Deoxyguanosine_C10H13N5O4
type: Species

956148
stoichiometry: 1.0
species: 877866
type: SpeciesReference

904393
is: http://identifiers.org/ec-code/1.2.1.27
type: Reaction
reactant: 940079
product: 940127
product: 940103
reactant: 940091
reactant: 940019
reactant: 940007
reactant: 940067
reactant: 940055
product: 940139
product: 940151
reactant: 940043
reactant: 940031
reversible: false
product: 940115
fast: false
product: 940175
is: ENSPTRG00000006531.3
product: 940187
is: http://identifiers.org/ec-code/1.2.1.21
notes: R_MMSAD3m subsystem: Propanoate Metabolism R_MMSAD3m equation: [m] : coa + msa + nad --> accoa + co2 + nadh R_MMSAD1m subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMSAD1m equation: [m] : 2mop + coa + nad --> co2 + nadh + ppcoa R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh
product: 940163

894236
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 29_C213H340N15O179S9X
type: Species

885913
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dCDP_C9H12N3O10P2
type: Species

981735
stoichiometry: 1.0
species: 876996
type: SpeciesReference

925801
stoichiometry: 1.0
species: 903452
type: SpeciesReference

884669
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Ceramide 1-phosphate_C18H35NO5PFULLRCO
type: Species

988120
stoichiometry: 3.0
species: 881813
type: SpeciesReference

969136
stoichiometry: 1.0
species: 891110
type: SpeciesReference

992632
stoichiometry: 1.0
species: 880885
type: SpeciesReference

906883
type: Reaction
product: 962427
product: 962415
reactant: 962355
is: ENSPTRG00000015935.4
notes: R_TAURt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_TAURt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + taur[e] <==> (2) na1[c] + taur[c] R_TAURtcx subsystem: Taurine and hypotaurine metabolism R_TAURtcx equation: na1[c] + taur[c] <==> na1[x] + taur[x]
reactant: 962367
reactant: 962379
product: 962439
reactant: 962391
fast: false
product: 962403
reversible: true

905153
stoichiometry: 2.0
species: 880317
type: SpeciesReference

896112
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1665H2740N20O570P20
type: Species

003294
stoichiometry: 1.0
species: 893490
type: SpeciesReference

933201
stoichiometry: 1.0
species: 886552
type: SpeciesReference

973012
stoichiometry: 1.0
species: 894530
type: SpeciesReference

911182
is: ENSPTRG00000021402.5
is: http://identifiers.org/ec-code/2.7.4.3
is: ENSPTRG00000006703.2
reactant: 000227
type: Reaction
product: 000240
fast: false
name: adenylate kinase
reversible: true
notes: R_ADK1 subsystem: Nucleotides R_ADK1 equation: [c] : amp + atp <==> (2) adp
reactant: 000214

995708
stoichiometry: 111.0
species: 897407
type: SpeciesReference

987506
stoichiometry: 2.0
species: 896016
type: SpeciesReference

962850
stoichiometry: 1.0
species: 903668
type: SpeciesReference

005935
stoichiometry: 1.0
species: 897492
type: SpeciesReference

907810
reactant: 970298
notes: R_MTHFDm subsystem: Folate Metabolism R_MTHFDm equation: [m] : mlthf + nadp <==> methf + nadph R_FTHFLm subsystem: Folate Metabolism R_FTHFLm equation: [m] : atp + for + thf <==> 10fthf + adp + pi R_MTHFCm subsystem: Folate Metabolism R_MTHFCm equation: [m] : h2o + methf <==> 10fthf + h
reactant: 970262
reactant: 970310
is: ENSPTRG00000029254.1
reactant: 970274
is: http://identifiers.org/ec-code/1.5.1.5
product: 970358
product: 970346
product: 970370
reactant: 970250
product: 970322
fast: false
is: http://identifiers.org/ec-code/6.3.4.3
reversible: true
reactant: 970238
is: ENSPTRG00000023039.2
is: ENSPTRG00000018710.4
type: Reaction
product: 970382
reactant: 970286
product: 970334
is: http://identifiers.org/ec-code/3.5.4.9

914498
stoichiometry: 1.0
species: 897189
type: SpeciesReference

943234
stoichiometry: 1.0
species: 886636
type: SpeciesReference

944821
stoichiometry: 1.0
species: 884946
type: SpeciesReference

942644
stoichiometry: 1.0
species: 902451
type: SpeciesReference

979389
stoichiometry: 2.0
species: 891555
type: SpeciesReference

882212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: androsterone glucuronide_C25H38O8
type: Species

887461
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dTDP_C10H13N2O11P2
type: Species

881993
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: S-aminomethyldihydrolipoamide_C9H21N2OS2
type: Species

995070
stoichiometry: 1.0
species: 893175
type: SpeciesReference

921591
stoichiometry: 2.0
species: 878325
type: SpeciesReference

908037
stoichiometry: 4.0
species: 884355
type: SpeciesReference

993054
stoichiometry: 1.0
species: 887290
type: SpeciesReference

951187
stoichiometry: 1.0
species: 901426
type: SpeciesReference

972541
stoichiometry: 1.0
species: 900641
type: SpeciesReference

953604
stoichiometry: 1.0
species: 882625
type: SpeciesReference

962706
stoichiometry: 2.0
species: 897528
type: SpeciesReference

950544
stoichiometry: 6.0
species: 885888
type: SpeciesReference

987434
stoichiometry: 1.0
species: 895919
type: SpeciesReference

911294
stoichiometry: 1.0
species: 903209
type: SpeciesReference

905152
fast: false
reactant: 945423
name: GDP-L-fucose synthase
reactant: 945411
notes: R_GFUCS subsystem: Fructose and Mannose Metabolism R_GFUCS equation: [c] : gdpddman + h + nadph --> gdpfuc + nadp
product: 945447
reactant: 945398
is: http://identifiers.org/ec-code/1.1.1.271
is: ENSPTRG00000020662.3
product: 945435
reversible: false
type: Reaction

882769
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Aspartate_C4H6NO4
type: Species

897924
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: nervonic acid_C24H45O2
type: Species

948002
stoichiometry: 1.0
species: 904681
type: SpeciesReference

961751
stoichiometry: 1.0
species: 903548
type: SpeciesReference

883470
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Cob(II)alamin_C62H92CoN13O14P
type: Species

890542
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Glycine_C2H5NO2
type: Species

004569
stoichiometry: 2.0
species: 880414
type: SpeciesReference

960087
stoichiometry: 1.0
species: 903452
type: SpeciesReference

979835
stoichiometry: 1.0
species: 903560
type: SpeciesReference

922218
stoichiometry: 1.0
species: 890326
type: SpeciesReference

944761
stoichiometry: 1.0
species: 882030
type: SpeciesReference

951623
stoichiometry: 1.0
species: 893406
type: SpeciesReference

889490
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)3 (GalNAc)1 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1_C64H112N3O36FULLRCO
type: Species

978169
stoichiometry: 1.0
species: 891868
type: SpeciesReference

970491
stoichiometry: 1.0
species: 895024
type: SpeciesReference

881282
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: ADP_C10H12N5O10P2
type: Species

930340
stoichiometry: 1.0
species: 898212
type: SpeciesReference

907075
stoichiometry: 1.0
species: 902186
type: SpeciesReference

965474
stoichiometry: 2.0
species: 903752
type: SpeciesReference

953071
stoichiometry: 1.0
species: 901549
type: SpeciesReference

962247
stoichiometry: 1.0
species: 888418
type: SpeciesReference

974183
stoichiometry: 1.0
species: 897864
type: SpeciesReference

931848
stoichiometry: 2.0
species: 882781
type: SpeciesReference

950254
stoichiometry: 1.0
species: 886021
type: SpeciesReference

970346
stoichiometry: 1.0
species: 881282
type: SpeciesReference

936424
stoichiometry: 1.0
species: 879186
type: SpeciesReference

898164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Oxaloacetate_C4H2O5
type: Species

922734
stoichiometry: 1.0
species: 894020
type: SpeciesReference

998682
stoichiometry: 23.0
species: 891616
type: SpeciesReference

004245
stoichiometry: 2.0
species: 885019
type: SpeciesReference

919257
stoichiometry: 1.0
species: 878108
type: SpeciesReference

896136
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C70H117N2O55X
type: Species

998537
stoichiometry: 1.0
species: 894675
type: SpeciesReference

995393
stoichiometry: 1.0
species: 892269
type: SpeciesReference

999794
stoichiometry: 1.0
species: 890686
type: SpeciesReference

879691
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Cystine_C6H12N2O4S2
type: Species

896281
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Malonyl-CoA_C24H33N7O19P3S
type: Species

887314
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dopamine_C8H12NO2
type: Species

934385
stoichiometry: 1.0
species: 892704
type: SpeciesReference

972263
stoichiometry: 1.0
species: 894591
type: SpeciesReference

928745
stoichiometry: 1.0
species: 884025
type: SpeciesReference

895484
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: linoleic coenzyme A_C39H62N7O17P3S
type: Species

952552
stoichiometry: 2.0
species: 889154
type: SpeciesReference

968160
stoichiometry: 2.0
species: 897443
type: SpeciesReference

949132
stoichiometry: 1.0
species: 894164
type: SpeciesReference

906882
stoichiometry: 2.0
species: 891664
type: SpeciesReference

893308
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Isopentenyl diphosphate_C5H9O7P2
type: Species

000087
stoichiometry: 1.0
species: 891483
type: SpeciesReference

898056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: O2_O2
type: Species

896849
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2
type: Species

889959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: GD3 (homo sapiens)_C52H88N3O28FULLRCO
type: Species

900558
product: 909930
reversible: true
is: ENSPTRG00000024082.4
product: 909942
type: Reaction
fast: false
product: 909918
reactant: 909881
reactant: 909893
product: 909954
reactant: 909905
name: phosphatidylcholine transporter
notes: R_PCt subsystem: Transport, Extracellular R_PCt equation: atp[c] + h2o[c] + pchol_hs[c] <==> adp[c] + h[c] + pchol_hs[e] + pi[c]

879799
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Protein N6,N6,N6-trimethyl-L-lysine_C3H10X
type: Species

905902
stoichiometry: 1.0
species: 889984
type: SpeciesReference

923182
stoichiometry: 2.0
species: 899530
type: SpeciesReference

972046
stoichiometry: 1.0
species: 894261
type: SpeciesReference

898852
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2
type: Species

002206
stoichiometry: 1.0
species: 899323
type: SpeciesReference

959242
stoichiometry: 1.0
species: 895000
type: SpeciesReference

939715
stoichiometry: 1.0
species: 901487
type: SpeciesReference

004753
stoichiometry: 1.0
species: 894963
type: SpeciesReference

947809
stoichiometry: 1.0
species: 894248
type: SpeciesReference

911579
reactant: 006067
is: ENSPTRG00000007031.2
fast: false
type: Reaction
reactant: 006043
product: 006139
product: 006103
reactant: 006079
product: 006091
product: 006127
product: 006115
notes: R_ADNt4 subsystem: Transport, Extracellular R_ADNt4 equation: adn[e] + na1[e] --> adn[c] + na1[c] R_URIt4 subsystem: Transport, Extracellular R_URIt4 equation: na1[e] + uri[e] --> na1[c] + uri[c] R_INSt4 subsystem: Transport, Extracellular R_INSt4 equation: ins[e] + na1[e] --> ins[c] + na1[c] R_GSNt4 subsystem: Transport, Extracellular R_GSNt4 equation: gsn[e] + na1[e] --> gsn[c] + na1[c]
reversible: false
reactant: 006055
reactant: 006031

911466
stoichiometry: 1.0
species: 890989
type: SpeciesReference

912251
stoichiometry: 1.0
species: 896487
type: SpeciesReference

900304
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Prostaglandin D2_C20H31O5
type: Species

922989
stoichiometry: 18.0
species: 891616
type: SpeciesReference

999608
stoichiometry: 3.0
species: 881764
type: SpeciesReference

W3 CDTF: Fri Feb 03 12:32:24 GMT 2012

906676
stoichiometry: 1.0
species: 890008
type: SpeciesReference

905251
stoichiometry: 1.0
species: 894927
type: SpeciesReference

899045
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2
type: Species

917115
stoichiometry: 33.0
species: 884706
type: SpeciesReference

903281
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Thiosulfate_O3S2
type: Species

951392
stoichiometry: 1.0
species: 881258
type: SpeciesReference

004692
stoichiometry: 1.0
species: 890216
type: SpeciesReference

961607
stoichiometry: 4.0
species: 891483
type: SpeciesReference

958950
stoichiometry: 1.0
species: 893430
type: SpeciesReference

953857
stoichiometry: 3.0
species: 891760
type: SpeciesReference

941977
stoichiometry: 1.0
species: 886889
type: SpeciesReference

937218
stoichiometry: 1.0
species: 901426
type: SpeciesReference

001461
stoichiometry: 1.0
species: 893478
type: SpeciesReference

963115
stoichiometry: 1.0
species: 881282
type: SpeciesReference

907629
reversible: false
is: ENSPTRG00000010970.4
product: 968472
reactant: 968376
reactant: 968400
product: 968484
type: Reaction
notes: R_PSFLIP subsystem: Transport, Extracellular R_PSFLIP equation: atp[c] + h2o[c] + ps_hs[e] --> adp[c] + h[c] + pi[c] + ps_hs[c] R_PEFLIP subsystem: Transport, Extracellular R_PEFLIP equation: atp[c] + h2o[c] + pe_hs[e] --> adp[c] + h[c] + pe_hs[c] + pi[c] R_PSFLIPm subsystem: Transport, Mitochondrial R_PSFLIPm equation: atp[c] + h2o[c] + ps_hs[c] --> adp[c] + h[c] + pi[c] + ps_hs[m] R_PEFLIPm subsystem: Transport, Mitochondrial R_PEFLIPm equation: atp[c] + h2o[c] + pe_hs[c] --> adp[c] + h[c] + pe_hs[m] + pi[c]
fast: false
product: 968460
reactant: 968412
reactant: 968388
product: 968520
product: 968508
reactant: 968436
product: 968496
product: 968448
reactant: 968424

955220
stoichiometry: 1.0
species: 901910
type: SpeciesReference

908595
stoichiometry: 1.0
species: 901513
type: SpeciesReference

910331
stoichiometry: 3.0
species: 881306
type: SpeciesReference

005007
stoichiometry: 1.0
species: 901621
type: SpeciesReference

990441
stoichiometry: 1.0
species: 894068
type: SpeciesReference

947749
stoichiometry: 1.0
species: 893996
type: SpeciesReference

997425
stoichiometry: 1.0
species: 882188
type: SpeciesReference

988905
stoichiometry: 1.0
species: 885659
type: SpeciesReference

928890
stoichiometry: 1.0
species: 892849
type: SpeciesReference

891495
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: H2O_H2O
type: Species

910656
stoichiometry: 3.0
species: 899530
type: SpeciesReference

W3 CDTF: Fri Feb 03 12:32:24 GMT 2012

909549
reactant: 986795
is: ENSPTRG00000029678.1
product: 986879
reactant: 986783
notes: R_DOLPGT3_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT3_Ler equation: [r] : (0.1) dolglcp_L + (0.1) g2m8mpdol_L --> (0.1) dolp_L + (0.1) g3m8mpdol_L + h R_DOLPGT3_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT3_Uer equation: [r] : (0.1) dolglcp_U + (0.1) g2m8mpdol_U --> (0.1) dolp_U + (0.1) g3m8mpdol_U + h
fast: false
product: 986855
product: 986831
type: Reaction
product: 986867
reactant: 986819
product: 986843
reversible: false
reactant: 986807
is: ENSPTRG00000004822.3

916236
stoichiometry: 1.0
species: 903391
type: SpeciesReference

892789
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: heparan sulfate, precursor 7_C73H109N4O58X
type: Species

990710
stoichiometry: 1.0
species: 897636
type: SpeciesReference

000048
stoichiometry: 1.0
species: 891230
type: SpeciesReference

987867
stoichiometry: 1.0
species: 899530
type: SpeciesReference

893139
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Imidazole-4-acetate_C5H5N2O2
type: Species

980222
stoichiometry: 1.0
species: 899250
type: SpeciesReference

007229
stoichiometry: 1.0
species: 882421
type: SpeciesReference

909237
reversible: true
is: ENSPTRG00000018405.5
notes: R_CMPACNAtg subsystem: Transport, Golgi Apparatus R_CMPACNAtg equation: cmp[g] + cmpacna[c] <==> cmp[c] + cmpacna[g]
name: CMP-Sia Golgi transport via CMP antiport
product: 983930
reactant: 983905
fast: false
product: 983942
type: Reaction
reactant: 983918

979113
stoichiometry: 1.0
species: 889454
type: SpeciesReference

008305
stoichiometry: 1.0
species: 883675
type: SpeciesReference

002655
stoichiometry: 1.0
species: 904657
type: SpeciesReference

985613
stoichiometry: 12.0
species: 891760
type: SpeciesReference

899347
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phosphatidyl glycerol phosphate (homo sapiens)_C6H11O9P2FULLRCO2FULLR2CO2
type: Species

989894
stoichiometry: 1.0
species: 894591
type: SpeciesReference

879547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: heptaglutamyl folate (THF)_C49H57N13O24
type: Species

997704
stoichiometry: 1.0
species: 895125
type: SpeciesReference

932247
stoichiometry: 1.0
species: 882090
type: SpeciesReference

878277
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _4,6-Dihydroxyquinoline_C9H7NO2
type: Species

909813
notes: R_UGALNACter subsystem: Transport, Endoplasmic Reticular R_UGALNACter equation: udpacgal[c] + ump[r] <==> udpacgal[r] + ump[c] R_UDPGLCAter subsystem: Transport, Endoplasmic Reticular R_UDPGLCAter equation: udpglcur[r] + ump[c] <==> udpglcur[c] + ump[r]
product: 989570
reactant: 989545
reactant: 989509
product: 989594
is: ENSPTRG00000000838.3
product: 989557
reactant: 989533
type: Reaction
product: 989582
reactant: 989521
fast: false
reversible: true

911577
stoichiometry: 1.0
species: 891483
type: SpeciesReference

912843
stoichiometry: 1.0
species: 888200
type: SpeciesReference

910221
stoichiometry: 1.0
species: 898901
type: SpeciesReference

903728
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: UMP_C9H11N2O9P
type: Species

W3 CDTF: Fri Feb 03 12:32:24 GMT 2012

000639
stoichiometry: 1.0
species: 876500
type: SpeciesReference

885260
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 3_C37H53NO44S4
type: Species

997631
stoichiometry: 1.0
species: 891604
type: SpeciesReference

918869
stoichiometry: 1.0
species: 886721
type: SpeciesReference

881101
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: O-Acetylcarnitine_C9H17NO4
type: Species

907906
product: 971539
is: http://identifiers.org/ec-code/3.6.1.6
is: http://identifiers.org/ec-code/2.7.4.9
modifier: 971599
modifier: 971575
product: 971551
reactant: 971503
notes: R_NDP8 subsystem: Nucleotides R_NDP8 equation: [c] : dudp + h2o --> dump + h + pi R_DTMPK subsystem: Nucleotides R_DTMPK equation: [c] : atp + dtmp <==> adp + dtdp
modifier: 971563
product: 971527
fast: false
reactant: 971515
modifier: 971587
is: ENSPTRG00000013129.4
type: Reaction
reversible: false

982590
stoichiometry: 1.0
species: 903488
type: SpeciesReference

931618
stoichiometry: 1.0
species: 897443
type: SpeciesReference

002414
stoichiometry: 2.0
species: 902836
type: SpeciesReference

987939
stoichiometry: 1.0
species: 887132
type: SpeciesReference

972361
stoichiometry: 2.0
species: 891483
type: SpeciesReference

907627
stoichiometry: 1.0
species: 902451
type: SpeciesReference

904549
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: XTP_C10H11N4O15P3
type: Species

943487
stoichiometry: 1.0
species: 892679
type: SpeciesReference

893731
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 30_C90H147N6O75S3
type: Species

010357
stoichiometry: 1.0
species: 879739
type: SpeciesReference

932174
stoichiometry: 1.0
species: 884085
type: SpeciesReference

930110
stoichiometry: 1.0
species: 881825
type: SpeciesReference

948195
stoichiometry: 1.0
species: 883143
type: SpeciesReference

915741
stoichiometry: 1.0
species: 880462
type: SpeciesReference

995914
stoichiometry: 2.0
species: 877020
type: SpeciesReference

960666
stoichiometry: 5.0
species: 891591
type: SpeciesReference

966890
stoichiometry: 1.0
species: 890362
type: SpeciesReference

007518
stoichiometry: 2.0
species: 881258
type: SpeciesReference

978714
stoichiometry: 1.0
species: 897528
type: SpeciesReference

941564
stoichiometry: 1.0
species: 885707
type: SpeciesReference

964290
stoichiometry: 1.0
species: 887412
type: SpeciesReference

903874
product: 935625
reactant: 935553
product: 935661
reactant: 935517
fast: false
type: Reaction
reactant: 935577
is: http://identifiers.org/ec-code/3.6.1.52
product: 935649
product: 935613
reactant: 935565
is: ENSPTRG00000014933.2
product: 935637
reactant: 935529
product: 935673
product: 935601
reactant: 935541
reversible: false
notes: R_PMI1346PHn subsystem: Inositol Phosphate Metabolism R_PMI1346PHn equation: [n] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI1346PH subsystem: Inositol Phosphate Metabolism R_PMI1346PH equation: [c] : h2o + ppmi1346p --> h + mi13456p + pi R_PMI12346PHn subsystem: Inositol Phosphate Metabolism R_PMI12346PHn equation: [n] : h2o + ppmi12346p --> h + minohp + pi R_PMI12346PH subsystem: Inositol Phosphate Metabolism R_PMI12346PH equation: [c] : h2o + ppmi12346p --> h + minohp + pi
is: ENSPTRG00000018056.3
product: 935589

910654
type: Reaction
name: glyceraldehyde-3-phosphate dehydrogenase
is: ENSPTRG00000010848.4
reactant: 995999
product: 996035
notes: R_GAPD subsystem: Glycolysis/Gluconeogenesis R_GAPD equation: [c] : g3p + nad + pi <==> 13dpg + h + nadh
reactant: 996023
reversible: true
product: 996060
reactant: 996011
fast: false
is: http://identifiers.org/ec-code/1.2.1.12
is: ENSPTRG00000004577.4
product: 996048

W3 CDTF: Fri Feb 03 12:32:24 GMT 2012

900860
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cis-11-retinal_C20H28O
type: Species

993706
stoichiometry: 1.0
species: 899626
type: SpeciesReference

993862
stoichiometry: 1.0
species: 884085
type: SpeciesReference

925668
stoichiometry: 1.0
species: 890326
type: SpeciesReference

962561
stoichiometry: 1.0
species: 881198
type: SpeciesReference

994431
stoichiometry: 1.0
species: 901525
type: SpeciesReference

948330
stoichiometry: 1.0
species: 895617
type: SpeciesReference

922085
stoichiometry: 1.0
species: 880981
type: SpeciesReference

921386
stoichiometry: 1.0
species: 899771
type: SpeciesReference

933539
stoichiometry: 1.0
species: 903488
type: SpeciesReference

968895
stoichiometry: 1.0
species: 890095
type: SpeciesReference

929976
stoichiometry: 1.0
species: 891555
type: SpeciesReference

901257
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Se-Adenosylselenohomocysteine_C14H20N6O5Se
type: Species

902632
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5
type: Species

923726
stoichiometry: 1.0
species: 890155
type: SpeciesReference

954143
stoichiometry: 1.0
species: 881499
type: SpeciesReference

908599
modifier: 979751
modifier: 979727
modifier: 979739
product: 979654
reactant: 979630
is: http://identifiers.org/ec-code/3.1.1.31
reactant: 979618
product: 979666
notes: R_PGLer subsystem: Pentose Phosphate Pathway R_PGLer equation: [r] : 6pgl + h2o --> 6pgc + h R_G6PDH2rer subsystem: Pentose Phosphate Pathway R_G6PDH2rer equation: [r] : g6p + nadp <==> 6pgl + h + nadph R_G6PDH1rer subsystem: Pentose Phosphate Pathway R_G6PDH1rer equation: [r] : g6p + nad <==> 6pgl + h + nadh R_G6PDH1er subsystem: Pentose Phosphate Pathway R_G6PDH1er equation: [r] : g6p + nad --> 6pgl + h + nadh
modifier: 979703
product: 979642
type: Reaction
reversible: false
modifier: 979715
product: 979678
reactant: 979606
is: ENSPTRG00000021305.5
modifier: 979763
modifier: 979691
fast: false
reactant: 979594

892245
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: heptadecanoate_C17H33O2
type: Species

884560
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: coumarin_C9H6O2
type: Species

908446
stoichiometry: 2.0
species: 896619
type: SpeciesReference

955076
stoichiometry: 1.0
species: 879065
type: SpeciesReference

913626
stoichiometry: 1.0
species: 882781
type: SpeciesReference

965246
stoichiometry: 1.0
species: 899578
type: SpeciesReference

973229
stoichiometry: 1.0
species: 893731
type: SpeciesReference

884415
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Coenzyme A_C21H32N7O16P3S
type: Species

990135
stoichiometry: 1.0
species: 894395
type: SpeciesReference

939679
stoichiometry: 2.0
species: 884620
type: SpeciesReference

902908
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Thymidine_C10H14N2O5
type: Species

918410
stoichiometry: 6.0
species: 884391
type: SpeciesReference

897395
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Nicotinamide adenine dinucleotide - reduced_C21H27N7O14P2
type: Species

910894
product: 997413
product: 997400
product: 997388
reversible: false
reactant: 997376
type: Reaction
reactant: 997328
is: http://identifiers.org/ec-code/1.14.99.9
reactant: 997364
fast: false
product: 997437
reactant: 997316
reactant: 997352
product: 997449
reactant: 997304
notes: R_P45017A4r subsystem: Steroid Metabolism R_P45017A4r equation: [r] : 17ahprgstrn + h + nadph + (0.5) o2 --> acald + andrstndn + h2o + nadp R_P45017A2r subsystem: Steroid Metabolism R_P45017A2r equation: [r] : 17ahprgnlone + h + nadph + (0.5) o2 --> acald + dhea + h2o + nadp R_P45017A1r subsystem: Steroid Metabolism R_P45017A1r equation: [r] : h + nadph + o2 + prgnlone --> 17ahprgnlone + h2o + nadp R_P45017A3r subsystem: Steroid Metabolism R_P45017A3r equation: [r] : h + nadph + o2 + prgstrn --> 17ahprgstrn + h2o + nadp
reactant: 997340
product: 997461
is: ENSPTRG00000002900.4
product: 997425

965390
stoichiometry: 1.0
species: 897492
type: SpeciesReference

895151
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Leukotriene A4_C20H29O3
type: Species

888103
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _16-Glucuronide-estriol_C24H32O9
type: Species

902631
reversible: true
reactant: 925512
product: 925596
product: 925620
reactant: 925488
reactant: 925536
notes: R_SUCCt2m subsystem: Transport, Mitochondrial R_SUCCt2m equation: pi[m] + succ[c] <==> pi[c] + succ[m] R_MALSO4tm subsystem: Transport, Mitochondrial R_MALSO4tm equation: mal-L[c] + so4[m] <==> mal-L[m] + so4[c] R_FUMTSULtm subsystem: Transport, Mitochondrial R_FUMTSULtm equation: fum[c] + tsul[m] <==> fum[m] + tsul[c] R_FUMSO3tm subsystem: Transport, Mitochondrial R_FUMSO3tm equation: fum[c] + so3[m] <==> fum[m] + so3[c] R_MALSO3tm subsystem: Transport, Mitochondrial R_MALSO3tm equation: mal-L[c] + so3[m] <==> mal-L[m] + so3[c] R_MALTSULtm subsystem: Transport, Mitochondrial R_MALTSULtm equation: mal-L[c] + tsul[m] <==> mal-L[m] + tsul[c] R_FUMSO4tm subsystem: Transport, Mitochondrial R_FUMSO4tm equation: fum[c] + so4[m] <==> fum[m] + so4[c] R_FUMtm subsystem: Transport, Mitochondrial R_FUMtm equation: fum[c] + pi[m] <==> fum[m] + pi[c] R_MALtm subsystem: Transport, Mitochondrial R_MALtm equation: mal-L[c] + pi[m] <==> mal-L[m] + pi[c]
product: 925584
product: 925632
reactant: 925500
reactant: 925476
reactant: 925524
product: 925560
type: Reaction
fast: false
is: ENSPTRG00000009770.3
product: 925572
reactant: 925548
product: 925608

889346
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: sn-Glycero-3-phosphocholine_C8H20NO6P
type: Species

897660
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Ammonium_H4N
type: Species

901258
product: 915175
product: 915163
fast: false
is: ENSPTRG00000011650.4
type: Reaction
is: http://identifiers.org/ec-code/4.1.1.17
reactant: 915151
reversible: false
notes: R_ORNDC subsystem: Urea cycle/amino group metabolism R_ORNDC equation: [c] : h + orn --> co2 + ptrc
reactant: 915138
name: Ornithine Decarboxylase

003090
stoichiometry: 1.0
species: 883795
type: SpeciesReference

953923
stoichiometry: 2.0
species: 903632
type: SpeciesReference

983966
stoichiometry: 1.0
species: 885272
type: SpeciesReference

916995
stoichiometry: 1.0
species: 904043
type: SpeciesReference

906679
type: Reaction
is: ENSPTRG00000008861.4
notes: R_GLCt4 subsystem: Transport, Extracellular R_GLCt4 equation: glc-D[e] + na1[e] <==> glc-D[c] + na1[c] R_INSTt4 subsystem: Transport, Extracellular R_INSTt4 equation: inost[e] + na1[e] <==> inost[c] + na1[c] R_NAt subsystem: Transport, Extracellular R_NAt equation: na1[e] <==> na1[c]
fast: false
product: 960944
product: 960932
reversible: true
reactant: 960919
reactant: 960907
product: 960956
reactant: 960895

891616
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: H+_H
type: Species

913798
stoichiometry: 1.0
species: 887033
type: SpeciesReference

952249
stoichiometry: 1.0
species: 899626
type: SpeciesReference

879114
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-Hydroxykynurenamine_C9H13N2O2
type: Species

907905
stoichiometry: 1.0
species: 889214
type: SpeciesReference

922770
stoichiometry: 1.0
species: 894297
type: SpeciesReference

992497
stoichiometry: 5.0
species: 897273
type: SpeciesReference

971287
stoichiometry: 11.0
species: 897347
type: SpeciesReference

877794
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Hydroxypropionyl-CoA_C24H36N7O18P3S
type: Species

965149
stoichiometry: 1.0
species: 892994
type: SpeciesReference

927187
stoichiometry: 2.0
species: 900641
type: SpeciesReference

878811
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8
type: Species

940055
stoichiometry: 2.0
species: 884427
type: SpeciesReference

975594
stoichiometry: 2.0
species: 898997
type: SpeciesReference

983567
stoichiometry: 1.0
species: 887534
type: SpeciesReference

976125
stoichiometry: 1.0
species: 883239
type: SpeciesReference

969865
stoichiometry: 8.0
species: 898056
type: SpeciesReference

955520
stoichiometry: 1.0
species: 883374
type: SpeciesReference

903283
product: 930520
is: ENSPTRG00000011723.4
reactant: 930508
product: 930556
reversible: false
notes: R_DNAMTSEn subsystem: Selenoamino acid metabolism R_DNAMTSEn equation: [n] : dna + seasmet --> dna5mtc + h + seahcys R_DNAMTn subsystem: Methionine Metabolism R_DNAMTn equation: [n] : amet + dna --> ahcys + dna5mtc + h
product: 930544
type: Reaction
reactant: 930496
reactant: 930484
is: ENSPTRG00000002327.5
product: 930532
is: ENSPTRG00000013384.4
is: http://identifiers.org/ec-code/2.1.1.37
fast: false

995166
stoichiometry: 1.0
species: 901922
type: SpeciesReference

898624
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Oxalate_C2O4
type: Species

894371
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 5_C101H164N7O75SX
type: Species

972940
stoichiometry: 1.0
species: 893792
type: SpeciesReference

915006
stoichiometry: 1.0
species: 900824
type: SpeciesReference

928300
stoichiometry: 1.0
species: 887582
type: SpeciesReference

923582
stoichiometry: 1.0
species: 891483
type: SpeciesReference

886069
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dCTP_C9H12N3O13P3
type: Species

904802
is: ENSPTRG00000016851.4
reversible: true
reactant: 943801
product: 943837
reactant: 943825
type: Reaction
reactant: 943813
name: NAD(P) transhydrogenase
product: 943861
product: 943849
is: http://identifiers.org/ec-code/1.6.1.1
fast: false
notes: R_THD1m subsystem: NAD Metabolism R_THD1m equation: h[c] + nadh[m] + nadp[m] <==> h[m] + nad[m] + nadph[m]

991977
stoichiometry: 3.0
species: 898478
type: SpeciesReference

903596
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: UDPglucose_C15H22N2O17P2
type: Species

892122
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Histamine_C5H10N3
type: Species

937097
stoichiometry: 8.0
species: 897273
type: SpeciesReference

957451
stoichiometry: 1.0
species: 895000
type: SpeciesReference

955628
stoichiometry: 4.0
species: 898985
type: SpeciesReference

983627
stoichiometry: 2.0
species: 891591
type: SpeciesReference

885380
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5b_C45H64N2O51S5X
type: Species

976958
stoichiometry: 6.0
species: 891748
type: SpeciesReference

975246
stoichiometry: 1.0
species: 881692
type: SpeciesReference

998115
stoichiometry: 2.0
species: 888672
type: SpeciesReference

958753
stoichiometry: 1.0
species: 891423
type: SpeciesReference

957897
stoichiometry: 3.0
species: 891591
type: SpeciesReference

882781
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: ATP_C10H12N5O13P3
type: Species

904801
stoichiometry: 1.0
species: 891483
type: SpeciesReference

912517
stoichiometry: 1.0
species: 877275
type: SpeciesReference

890518
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Glycine_C2H5NO2
type: Species

945496
stoichiometry: 1.0
species: 886528
type: SpeciesReference

913774
stoichiometry: 2.0
species: 877420
type: SpeciesReference

909239
stoichiometry: 1.0
species: 881258
type: SpeciesReference

980755
stoichiometry: 1.0
species: 896849
type: SpeciesReference

912674
stoichiometry: 1.0
species: 894927
type: SpeciesReference

928240
stoichiometry: 1.0
species: 889996
type: SpeciesReference

887885
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Eicosatetranoyl carnitine_C27H45NO4
type: Species

008026
stoichiometry: 1.0
species: 891591
type: SpeciesReference

994649
stoichiometry: 1.0
species: 897552
type: SpeciesReference

950942
stoichiometry: 5.0
species: 903488
type: SpeciesReference

974617
stoichiometry: 1.0
species: 902872
type: SpeciesReference

932597
stoichiometry: 1.0
species: 903728
type: SpeciesReference

981844
stoichiometry: 2.0
species: 891591
type: SpeciesReference

932487
stoichiometry: 1.0
species: 897395
type: SpeciesReference

925512
stoichiometry: 3.0
species: 899578
type: SpeciesReference

944303
stoichiometry: 1.0
species: 884013
type: SpeciesReference

896692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: (R)-Mevalonate_C6H11O4
type: Species

956172
stoichiometry: 8.0
species: 884319
type: SpeciesReference

876680
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _10-Formyltetrahydrofolate_C20H21N7O7
type: Species

950834
stoichiometry: 1.0
species: 900472
type: SpeciesReference

980463
stoichiometry: 1.0
species: 891591
type: SpeciesReference

963638
stoichiometry: 5.0
species: 882685
type: SpeciesReference

930931
stoichiometry: 1.0
species: 879871
type: SpeciesReference

930652
stoichiometry: 1.0
species: 897261
type: SpeciesReference

996109
stoichiometry: 1.0
species: 882017
type: SpeciesReference

000338
stoichiometry: 1.0
species: 886660
type: SpeciesReference

982265
stoichiometry: 1.0
species: 891664
type: SpeciesReference

902042
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Sucrose_C12H22O11
type: Species

989654
stoichiometry: 1.0
species: 894346
type: SpeciesReference

987626
stoichiometry: 1.0
species: 881993
type: SpeciesReference

900014
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Pregnenolone_C21H32O2
type: Species

983216
stoichiometry: 1.0
species: 889370
type: SpeciesReference

988277
stoichiometry: 1.0
species: 904079
type: SpeciesReference

939522
stoichiometry: 1.0
species: 896318
type: SpeciesReference

909609
is: ENSPTRG00000010141.3
reactant: 987266
product: 987302
fast: false
is: ENSPTRG00000016880.4
notes: R_PPAP subsystem: Triacylglycerol Synthesis R_PPAP equation: [c] : h2o + pa_hs --> dag_hs + pi
product: 987290
reactant: 987278
is: http://identifiers.org/ec-code/3.1.3.4
is: ENSPTRG00000000787.4
name: phosphatidic acid phosphatase
type: Reaction
reversible: false

906523
product: 960014
reactant: 959930
reactant: 959966
type: Reaction
is: http://identifiers.org/ec-code/2.1.1.6
fast: false
reactant: 959942
product: 959978
product: 960026
product: 960002
notes: R_34DHPHAMT subsystem: Tyrosine metabolism R_34DHPHAMT equation: [c] : 34dhpha + amet --> ahcys + h + homoval R_DOPAMT subsystem: Tyrosine metabolism R_DOPAMT equation: [c] : amet + dopa --> 3moxtyr + ahcys + h R_SALMCOM subsystem: Tyrosine metabolism R_SALMCOM equation: [c] : amet + nrpphr --> ahcys + h + normete-L
product: 959990
reversible: false
is: ENSPTRG00000014466.4
reactant: 959954

903598
fast: false
product: 933502
is: ENSPTRG00000008792.3
product: 933478
reactant: 933382
reactant: 933346
product: 933418
reversible: false
type: Reaction
product: 933442
product: 933466
product: 933430
reactant: 933370
notes: R_S3T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T3g equation: [g] : hs_pre15 + paps --> h + hspg + pap R_PRFGS subsystem: IMP Biosynthesis R_PRFGS equation: [c] : atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi
is: http://identifiers.org/ec-code/6.3.5.3
is: http://identifiers.org/ec-code/2.8.2.23
product: 933454
product: 933490
reactant: 933394
reactant: 933358
reactant: 933406

884133
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: clupanodonyl CoA_C43H64N7O17P3S
type: Species

909541
stoichiometry: 1.0
species: 896233
type: SpeciesReference

008719
stoichiometry: 1.0
species: 903812
type: SpeciesReference

990027
stoichiometry: 1.0
species: 894140
type: SpeciesReference

996060
stoichiometry: 1.0
species: 897395
type: SpeciesReference

909069
product: 982602
type: Reaction
is: ENSPTRG00000013919.4
product: 982590
reactant: 982566
product: 982578
reversible: false
name: Beta-1,3-galactosyltransferase 5
notes: R_B3GALT5g subsystem: Sphingolipid Metabolism R_B3GALT5g equation: [g] : gbside_hs + udpgal --> galgbside_hs + h + udp
reactant: 982554
fast: false

997196
stoichiometry: 1.0
species: 900860
type: SpeciesReference

885152
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 5_C31H48NO32S2
type: Species

879005
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5 hydroxy omeprazole_C17H19N3O4S
type: Species

971178
stoichiometry: 1.0
species: 880426
type: SpeciesReference

947387
stoichiometry: 1.0
species: 899807
type: SpeciesReference

949581
stoichiometry: 1.0
species: 879955
type: SpeciesReference

925019
stoichiometry: 1.0
species: 879306
type: SpeciesReference

923472
stoichiometry: 1.0
species: 888454
type: SpeciesReference

928456
stoichiometry: 1.0
species: 889010
type: SpeciesReference

942800
stoichiometry: 1.0
species: 882553
type: SpeciesReference

892353
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 12_C55H82N3O64S6
type: Species

957221
stoichiometry: 5.0
species: 891591
type: SpeciesReference

926404
stoichiometry: 1.0
species: 877902
type: SpeciesReference

971455
stoichiometry: 11.0
species: 897407
type: SpeciesReference

935047
stoichiometry: 1.0
species: 893127
type: SpeciesReference

975135
stoichiometry: 5.0
species: 881258
type: SpeciesReference

876536
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19
type: Species

890446
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: glucocerebroside (homo sapiens)_C24H46NO7FULLRCO
type: Species

901101
reactant: 914039
is: ENSPTRG00000014991.3
reversible: false
reactant: 914063
reactant: 914051
name: _5-aminolevulinate synthase
product: 914100
product: 914076
notes: R_ALASm subsystem: Glycine, Serine, and Threonine Metabolism R_ALASm equation: [m] : gly + h + succoa --> 5aop + co2 + coa
is: http://identifiers.org/ec-code/2.3.1.37
type: Reaction
product: 914088
is: ENSPTRG00000021947.4
fast: false

923618
stoichiometry: 1.0
species: 890326
type: SpeciesReference

954035
stoichiometry: 1.0
species: 897467
type: SpeciesReference

909969
reactant: 991424
fast: false
modifier: 991641
reactant: 991484
reactant: 991448
reactant: 991412
product: 991581
product: 991545
reactant: 991436
is: http://identifiers.org/ec-code/2.3.1.38
product: 991569
modifier: 991629
reactant: 991388
product: 991617
product: 991497
product: 991533
modifier: 991689
notes: R_FAS180COA subsystem: Fatty acid elongation R_FAS180COA equation: [c] : (3) h + malcoa + (2) nadph + pmtcoa --> co2 + coa + h2o + (2) nadp + stcoa R_FAS140COA subsystem: Fatty acid elongation R_FAS140COA equation: [c] : ddcacoa + (3) h + malcoa + (2) nadph --> co2 + coa + h2o + (2) nadp + tdcoa R_FAS160COA subsystem: Fatty acid elongation R_FAS160COA equation: [c] : (3) h + malcoa + (2) nadph + tdcoa --> co2 + coa + h2o + (2) nadp + pmtcoa R_FAS100COA subsystem: Fatty acid elongation R_FAS100COA equation: [c] : (3) h + malcoa + (2) nadph + occoa --> co2 + coa + dcacoa + h2o + (2) nadp R_KAS8 subsystem: Fatty acid elongation R_KAS8 equation: [c] : accoa + (20) h + (7) malcoa + (14) nadph --> (7) co2 + (8) coa + (6) h2o + hdca + (14) nadp R_MCOATA subsystem: Fatty Acid Metabolism R_MCOATA equation: [c] : ACP + malcoa <==> coa + malACP R_FAS120COA subsystem: Fatty acid elongation R_FAS120COA equation: [c] : dcacoa + (3) h + malcoa + (2) nadph --> co2 + coa + ddcacoa + h2o + (2) nadp R_ACOATA subsystem: Fatty Acid Metabolism R_ACOATA equation: [c] : ACP + accoa <==> acACP + coa R_FAS80COA_L subsystem: Fatty acid elongation R_FAS80COA_L equation: [c] : accoa + (9) h + (3) malcoa + (6) nadph --> (3) co2 + (3) coa + (3) h2o + (6) nadp + occoa
reversible: false
modifier: 991677
product: 991521
type: Reaction
reactant: 991400
modifier: 991665
product: 991557
is: http://identifiers.org/ec-code/2.3.1.41
product: 991509
reactant: 991472
is: http://identifiers.org/ec-code/2.3.1.86
is: ENSPTRG00000009791.3
product: 991605
modifier: 991653
product: 991593
reactant: 991460
is: http://identifiers.org/ec-code/2.3.1.39

877227
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _2-Decaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone_C58H88O4
type: Species

940163
stoichiometry: 1.0
species: 894987
type: SpeciesReference

928555
stoichiometry: 11.0
species: 891616
type: SpeciesReference

996473
stoichiometry: 1.0
species: 900580
type: SpeciesReference

977226
stoichiometry: 1.0
species: 890819
type: SpeciesReference

986034
stoichiometry: 1.0
species: 891531
type: SpeciesReference

934493
stoichiometry: 1.0
species: 900460
type: SpeciesReference

947497
stoichiometry: 20.0
species: 903452
type: SpeciesReference

994757
stoichiometry: 1.0
species: 876765
type: SpeciesReference

973675
stoichiometry: 1.0
species: 887618
type: SpeciesReference

892013
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S
type: Species

972831
stoichiometry: 1.0
species: 901143
type: SpeciesReference

910053
type: Reaction
reactant: 992316
reversible: true
is: ENSPTRG00000004827.2
reactant: 992328
fast: false
product: 992341
product: 992353
name: inositol transport in via proton symport
notes: R_INSTt2r subsystem: Transport, Extracellular R_INSTt2r equation: h[e] + inost[e] <==> h[c] + inost[c]

962415
stoichiometry: 1.0
species: 897297
type: SpeciesReference

900016
type: Reaction
notes: R_MTAP subsystem: Arginine and Proline Metabolism R_MTAP equation: [c] : 5mta + pi --> 5mdr1p + ade
is: ENSPTRG00000020825.4
fast: false
reactant: 906786
product: 906810
reversible: false
reactant: 906774
product: 906798
name: _5'-methylthioadenosine phosphorylase
is: http://identifiers.org/ec-code/2.4.2.28

935301
stoichiometry: 2.0
species: 881258
type: SpeciesReference

891832
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Hexadecanoate (n-C16:0)_C16H31O2
type: Species

983410
stoichiometry: 1.0
species: 898925
type: SpeciesReference

001713
stoichiometry: 1.0
species: 893744
type: SpeciesReference

913085
stoichiometry: 1.0
species: 880909
type: SpeciesReference

984038
stoichiometry: 1.0
species: 884922
type: SpeciesReference

903174
reactant: 929686
type: Reaction
product: 929699
reactant: 929637
reactant: 929662
product: 929735
notes: R_P4507B11r subsystem: Bile Acid Biosynthesis R_P4507B11r equation: [r] : h + nadph + o2 + xol25oh --> h2o + nadp + xoltri25 R_P4507B12r subsystem: Bile Acid Biosynthesis R_P4507B12r equation: [r] : h + nadph + o2 + xol27oh --> h2o + nadp + xoltri27
product: 929723
fast: false
reversible: false
is: ENSPTRG00000020297.2
reactant: 929649
reactant: 929674
product: 929711

929396
stoichiometry: 2.0
species: 895375
type: SpeciesReference

915307
stoichiometry: 1.0
species: 897225
type: SpeciesReference

010429
stoichiometry: 2.0
species: 891591
type: SpeciesReference

977904
stoichiometry: 1.0
species: 881439
type: SpeciesReference

949267
stoichiometry: 1.0
species: 882853
type: SpeciesReference

922830
stoichiometry: 1.0
species: 894591
type: SpeciesReference

993379
stoichiometry: 1.0
species: 887764
type: SpeciesReference

888828
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Type IIH glycolipid_C50H89N2O26FULLRCO
type: Species

909348
stoichiometry: 1.0
species: 902932
type: SpeciesReference

887776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _8,9 epxoy aflatoxin B1_C17H12O7
type: Species

973747
stoichiometry: 2.0
species: 889996
type: SpeciesReference

908443
reactant: 978037
reactant: 977772
reactant: 977832
product: 978253
product: 978169
reactant: 977748
product: 978265
reactant: 978013
reactant: 977965
product: 978145
reactant: 977712
reactant: 977856
product: 978446
product: 978241
product: 978157
reactant: 977941
modifier: 978544
reactant: 977868
reactant: 977989
reactant: 977904
reactant: 978073
reactant: 977784
product: 978217
product: 978482
product: 978506
reactant: 977916
product: 978229
reactant: 977760
product: 978109
reversible: false
reactant: 977808
type: Reaction
product: 978205
product: 978385
reactant: 977953
modifier: 978531
product: 978494
reactant: 977700
fast: false
product: 978397
reactant: 978001
notes: R_LGNCCPT1 subsystem: Carnitine shuttle R_LGNCCPT1 equation: [c] : crn + lgnccoa --> coa + lgnccrn R_TETPENT3CPT1 subsystem: Carnitine shuttle R_TETPENT3CPT1 equation: [c] : crn + tetpent3coa --> coa + tetpent3crn R_ELAIDCPT1 subsystem: Carnitine shuttle R_ELAIDCPT1 equation: [c] : crn + od2coa --> coa + elaidcrn R_ADRNCPT1 subsystem: Carnitine shuttle R_ADRNCPT1 equation: [c] : adrncoa + crn --> adrncrn + coa R_DCSPTN1CPT1 subsystem: Carnitine shuttle R_DCSPTN1CPT1 equation: [c] : crn + dcsptn1coa --> coa + dcsptn1crn R_C204CPT1 subsystem: Carnitine shuttle R_C204CPT1 equation: [c] : arachdcoa + crn --> arachdcrn + coa R_DLNLCGCPT1 subsystem: Carnitine shuttle R_DLNLCGCPT1 equation: [c] : crn + dlnlcgcoa --> coa + dlnlcgcrn R_TMNDNCCPT1 subsystem: Carnitine shuttle R_TMNDNCCPT1 equation: [c] : crn + tmndnccoa --> coa + tmndnccrn R_C180CPT1 subsystem: Carnitine shuttle R_C180CPT1 equation: [c] : crn + stcoa --> coa + stcrn R_LNLNCGCPT1 subsystem: Carnitine shuttle R_LNLNCGCPT1 equation: [c] : crn + lnlncgcoa --> coa + lnlncgcrn R_TTDCPT1 subsystem: Carnitine shuttle R_TTDCPT1 equation: [c] : crn + tdcoa --> coa + ttdcrn R_NRVNCCPT1 subsystem: Carnitine shuttle R_NRVNCCPT1 equation: [c] : crn + nrvnccoa --> coa + nrvnccrn R_LNLNCACPT1 subsystem: Carnitine shuttle R_LNLNCACPT1 equation: [c] : crn + lnlncacoa --> coa + lnlncacrn R_VACCCPT1 subsystem: Carnitine shuttle R_VACCCPT1 equation: [c] : crn + vacccoa --> coa + vacccrn R_PTDCACRNCPT1 subsystem: Carnitine shuttle R_PTDCACRNCPT1 equation: [c] : crn + ptdcacoa --> coa + ptdcacrn R_CLPNDCPT1 subsystem: Carnitine shuttle R_CLPNDCPT1 equation: [c] : clpndcoa + crn --> clpndcrn + coa R_EICOSTETCPT1 subsystem: Carnitine shuttle R_EICOSTETCPT1 equation: [c] : crn + eicostetcoa --> coa + eicostetcrn R_C160CPT1 subsystem: Carnitine shuttle R_C160CPT1 equation: [c] : crn + pmtcoa --> coa + pmtcrn R_RTOTAL3CRNCPT1 subsystem: Carnitine shuttle R_RTOTAL3CRNCPT1 equation: [c] : Rtotal3coa + crn --> Rtotal3crn + coa R_LNLCCPT1 s…
product: 978121
product: 978361
product: 978277
product: 978421
product: 978181
reactant: 978049
product: 978133
reactant: 977844
product: 978373
product: 978409
product: 978289
product: 978193
reactant: 977977
reactant: 977724
reactant: 978097
reactant: 978025
reactant: 977820
is: http://identifiers.org/ec-code/4.2.1.1
reactant: 977736
product: 978349
product: 978434
reactant: 977880
product: 978458
is: http://identifiers.org/ec-code/2.3.1.21
product: 978301
product: 978325
reactant: 978085
reactant: 977892
product: 978313
reactant: 977796
reactant: 977929
product: 978337
is: ENSPTRG00000009482.3
modifier: 978519
reactant: 978061
product: 978470

924594
stoichiometry: 2.0
species: 903488
type: SpeciesReference

966951
stoichiometry: 1.0
species: 897237
type: SpeciesReference

881680
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide_C9H13N4O8P
type: Species

909967
stoichiometry: 2.0
species: 881740
type: SpeciesReference

936856
stoichiometry: 1.0
species: 882030
type: SpeciesReference

902043
is: http://identifiers.org/ec-code/3.2.1.106
type: Reaction
name: mannosyl-oligosaccharide glucosidase, endoplasmic reticulum
reactant: 920855
fast: false
product: 920867
reactant: 920843
reversible: false
is: ENSPTRG00000012089.3
product: 920879
notes: R_MG1er subsystem: N-Glycan Biosynthesis R_MG1er equation: [r] : g3m8masn + h2o --> g2m8masn + glc-D

890020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GDP_C10H12N5O11P2
type: Species

925212
stoichiometry: 1.0
species: 883747
type: SpeciesReference

998224
stoichiometry: 1.0
species: 881282
type: SpeciesReference

906114
product: 955460
reactant: 955376
product: 955412
reversible: false
product: 955424
reactant: 955388
is: http://identifiers.org/ec-code/2.4.1.41
is: ENSPTRG00000009972.2
product: 955436
is: http://identifiers.org/ec-code/3.2.1.24
fast: false
reactant: 955364
type: Reaction
product: 955448
reactant: 955400
notes: R_A_MANASE subsystem: N-Glycan Degradation R_A_MANASE equation: [c] : (2) h2o + m2mn --> (2) man + mn R_GALNTg subsystem: O-Glycan Biosynthesis R_GALNTg equation: [g] : Ser/Thr + udpacgal --> Tn_antigen + h + udp

920079
stoichiometry: 1.0
species: 882090
type: SpeciesReference

911998
stoichiometry: 1.0
species: 877492
type: SpeciesReference

955737
stoichiometry: 2.0
species: 897516
type: SpeciesReference

929662
stoichiometry: 2.0
species: 897552
type: SpeciesReference

005429
stoichiometry: 2.0
species: 891748
type: SpeciesReference

963224
stoichiometry: 1.0
species: 882805
type: SpeciesReference

968472
stoichiometry: 1.0
species: 899178
type: SpeciesReference

899457
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Phenylpyruvate_C9H7O3
type: Species

980330
stoichiometry: 1.0
species: 881258
type: SpeciesReference

883034
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Bilirubin_C33H34N4O6
type: Species

953700
stoichiometry: 1.0
species: 883326
type: SpeciesReference

990867
stoichiometry: 1.0
species: 903596
type: SpeciesReference

908379
stoichiometry: 1.0
species: 881198
type: SpeciesReference

937109
stoichiometry: 1.0
species: 900220
type: SpeciesReference

969706
stoichiometry: 1.0
species: 880680
type: SpeciesReference

905794
stoichiometry: 2.0
species: 883771
type: SpeciesReference

961715
stoichiometry: 1.0
species: 903596
type: SpeciesReference

956304
stoichiometry: 1.0
species: 880087
type: SpeciesReference

959218
stoichiometry: 16.0
species: 891483
type: SpeciesReference

970782
stoichiometry: 10.0
species: 897395
type: SpeciesReference

913494
stoichiometry: 1.0
species: 895112
type: SpeciesReference

919595
stoichiometry: 1.0
species: 899359
type: SpeciesReference

972082
stoichiometry: 1.0
species: 894346
type: SpeciesReference

939259
stoichiometry: 3.0
species: 891483
type: SpeciesReference

946666
stoichiometry: 1.0
species: 891808
type: SpeciesReference

961029
stoichiometry: 1.0
species: 897116
type: SpeciesReference

906326
stoichiometry: 1.0
species: 899033
type: SpeciesReference

001353
stoichiometry: 3.0
species: 897443
type: SpeciesReference

943595
stoichiometry: 1.0
species: 900788
type: SpeciesReference

951935
stoichiometry: 3.0
species: 886444
type: SpeciesReference

010576
stoichiometry: 1.0
species: 902572
type: SpeciesReference

958840
stoichiometry: 2.0
species: 897371
type: SpeciesReference

969571
stoichiometry: 5.0
species: 903644
type: SpeciesReference

884355
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: CO2_CO2
type: Species

999356
stoichiometry: 1.0
species: 883215
type: SpeciesReference

908378
is: http://identifiers.org/ec-code/2.3.1.51
is: ENSPTRG00000018779.5
is: ENSPTRG00000019949.3
reversible: false
is: ENSPTRG00000020196.3
type: Reaction
reactant: 977055
name: _1-acylglycerol-3-phosphate O-acyltransferase 1
is: ENSPTRG00000021564.4
product: 977080
fast: false
reactant: 977067
is: ENSPTRG00000013964.5
product: 977092
notes: R_AGPAT1 subsystem: Triacylglycerol Synthesis R_AGPAT1 equation: [c] : Rtotal2coa + alpa_hs --> coa + pa_hs

916127
stoichiometry: 1.0
species: 888792
type: SpeciesReference

009851
stoichiometry: 1.0
species: 891146
type: SpeciesReference

928781
stoichiometry: 1.0
species: 884013
type: SpeciesReference

960980
stoichiometry: 1.0
species: 892691
type: SpeciesReference

965037
stoichiometry: 1.0
species: 878469
type: SpeciesReference

000905
stoichiometry: 1.0
species: 900412
type: SpeciesReference

005622
stoichiometry: 4.0
species: 891014
type: SpeciesReference

903173
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Tryptophan_C11H12N2O2
type: Species

989786
stoichiometry: 1.0
species: 880692
type: SpeciesReference

997316
stoichiometry: 1.0
species: 900075
type: SpeciesReference

898128
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Superoxide anion_O2
type: Species

896995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: (S)-Methylmalonyl-CoA_C25H35N7O19P3S
type: Species

904658
product: 942752
reactant: 942376
is: http://identifiers.org/ec-code/2.3.1.16
product: 942836
product: 942776
product: 942668
reactant: 942582
reactant: 942534
product: 942884
product: 942740
reactant: 942620
type: Reaction
reactant: 942388
product: 942764
reactant: 942644
product: 942656
reversible: false
product: 942800
product: 942716
reactant: 942461
notes: R_FAOXC2251836x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2251836x equation: [x] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC180x equation: [x] : coa + h2o + nad + o2 + stcoa --> accoa + h + h2o2 + nadh + pmtcoa R_FAOXC241181x subsystem: Fatty acid oxidation, peroxisome R_FAOXC241181x equation: [x] : (3) coa + (3) h2o + (3) nad + nrvnccoa + (3) o2 --> (3) accoa + (3) h + (3) h2o2 + (3) nadh + odecoa R_PEROXx subsystem: Fatty acid oxidation, peroxisome R_PEROXx equation: [x] : (3) coa + (3) h2o + (3) nad + (2) o2 + pristcoa --> accoa + dmnoncoa + (3) h + (2) h2o2 + (3) nadh + (2) ppcoa R_FAOXC2452253x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2452253x equation: [x] : coa + h2o + nad + o2 + tetpent3coa --> accoa + clpndcoa + h + h2o2 + nadh R_FAOXC2252053x subsystem: Fatty acid oxidation, peroxisome R_FAOXC2252053x equation: [x] : coa + dcsptn1coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + tmndnccoa R_FAOXC183806x subsystem: Fatty acid oxidation, peroxisome R_FAOXC183806x equation: [x] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC200180x subsystem: Fatty acid oxidation, peroxisome R_FAOXC200180x equation: [x] : arachcoa + coa + h2o + nad + o2 --> accoa + h + h2o2 + nadh + stcoa R_ACACT7p subsystem: Fatty Acid Metabolism R_ACACT7p equation: [x] : 3ohdcoa + coa --> accoa + tdcoa R_ACACT8p subsystem: Fatty Acid Metabolism R_ACACT8p equation: [x] : 3ohodcoa + coa --> accoa + pmtcoa R_FAOXC246226x subsystem: Fatty acid oxidation, peroxisome R_FAOXC246226x equation: [x] : coa + h2o + nad + o2 + tethex3coa --> accoa + c226coa + h + h2o2 + nadh R_ACACT5p subsystem: Fatty Acid Metabolism R_ACACT5p equation: [x] : 3oddcoa + coa --> accoa + dcacoa R_FAOXC260240x subsystem: Fatty acid oxidation, peroxisome R_FAOXC260240x equation: [x] : coa + h2o + hexccoa + nad + o2 --> accoa + h + h2o2 +…
product: 942872
is: http://identifiers.org/ec-code/1.3.99.3
reactant: 942425
fast: false
product: 942824
reactant: 942485
product: 942896
reactant: 942449
product: 942704
reactant: 942594
reactant: 942340
reactant: 942558
product: 942812
product: 942728
reactant: 942607
reactant: 942546
reactant: 942364
product: 942921
reactant: 942328
reactant: 942412
reactant: 942570
product: 942860
reactant: 942473
product: 942788
reactant: 942437
is: ENSPTRG00000014752.4
reactant: 942521
product: 942933
product: 942909
reactant: 942497
product: 942848
reactant: 942632
reactant: 942509
reactant: 942352
reactant: 942400
product: 942692
product: 942680

002763
stoichiometry: 35.0
species: 897383
type: SpeciesReference

893840
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 39_C48H81N3O36
type: Species

962283
stoichiometry: 1.0
species: 897407
type: SpeciesReference

885731
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dADP_C10H12N5O9P2
type: Species

003390
stoichiometry: 1.0
species: 893924
type: SpeciesReference

930328
stoichiometry: 1.0
species: 880317
type: SpeciesReference

934099
stoichiometry: 2.0
species: 888623
type: SpeciesReference

909345
notes: R_URCN subsystem: Histidine Metabolism R_URCN equation: [c] : h2o + urcan --> 4izp
reversible: false
name: urocanase
fast: false
is: ENSPTRG00000015334.2
is: http://identifiers.org/ec-code/4.2.1.49
reactant: 984748
type: Reaction
reactant: 984760
product: 984772

944749
stoichiometry: 1.0
species: 890506
type: SpeciesReference

976515
stoichiometry: 2.0
species: 891591
type: SpeciesReference

936712
stoichiometry: 1.0
species: 885744
type: SpeciesReference

941674
stoichiometry: 1.0
species: 903464
type: SpeciesReference

910764
stoichiometry: 1.0
species: 897321
type: SpeciesReference

937955
stoichiometry: 4.0
species: 891591
type: SpeciesReference

982049
stoichiometry: 3.0
species: 881258
type: SpeciesReference

910330
product: 993174
is: http://identifiers.org/ec-code/2.3.1.42
notes: R_DHAPA subsystem: Triacylglycerol Synthesis R_DHAPA equation: [c] : Rtotalcoa + dhap --> adhap_hs + coa R_DHAPAx subsystem: Triacylglycerol Synthesis R_DHAPAx equation: [x] : Rtotalcoa + dhap --> adhap_hs + coa
reactant: 993102
is: ENSPTRG00000002107.5
reversible: false
reactant: 993126
product: 993162
fast: false
type: Reaction
reactant: 993114
reactant: 993138
product: 993186
product: 993150

876947
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _1-alpha,25-Dihydroxyvitamin D3_C27H44O3
type: Species

905608
product: 951743
product: 951791
reactant: 951671
is: http://identifiers.org/ec-code/1.5.1.8
notes: R_SACCD3m subsystem: Lysine Metabolism R_SACCD3m equation: [m] : akg + h + lys-L + nadph --> h2o + nadp + saccrp-L R_SACCD4m subsystem: Lysine Metabolism R_SACCD4m equation: [m] : h2o + nadp + saccrp-L --> L2aadp6sa + glu-L + h + nadph
product: 951767
reactant: 951683
product: 951815
product: 951755
product: 951803
reactant: 951719
is: http://identifiers.org/ec-code/1.5.1.10
type: Reaction
reversible: false
product: 951779
reactant: 951659
reactant: 951731
reactant: 951707
is: ENSPTRG00000023614.2
reactant: 951695
fast: false

947074
stoichiometry: 9.0
species: 898032
type: SpeciesReference

930000
stoichiometry: 1.0
species: 881668
type: SpeciesReference

940597
stoichiometry: 1.0
species: 899530
type: SpeciesReference

904657
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: zymosterol intermediate 2_C27H42O
type: Species

908150
product: 975099
product: 975172
is: ENSPTRG00000005971.4
product: 975123
reactant: 975038
reactant: 975087
product: 975160
reactant: 975062
reactant: 975026
product: 975148
product: 975184
fast: false
reactant: 975050
notes: R_CAMPt subsystem: Transport, Extracellular R_CAMPt equation: atp[c] + camp[c] + h2o[c] --> adp[c] + camp[e] + h[c] + pi[c] R_PROSTGE2t3 subsystem: Transport, Extracellular R_PROSTGE2t3 equation: atp[c] + h2o[c] + prostge2[c] --> adp[c] + h[c] + pi[c] + prostge2[e] R_ESTRADIOLGLCt2 subsystem: Transport, Extracellular R_ESTRADIOLGLCt2 equation: atp[c] + estradiolglc[c] + h2o[c] --> adp[c] + estradiolglc[e] + h[c] + pi[c] R_CGMPt subsystem: Transport, Extracellular R_CGMPt equation: _35cgmp[c] + atp[c] + h2o[c] --> 35cgmp[e] + adp[c] + h[c] + pi[c] R_PROSTGE1t3 subsystem: Transport, Extracellular R_PROSTGE1t3 equation: atp[c] + h2o[c] + prostge1[c] --> adp[c] + h[c] + pi[c] + prostge1[e]
reactant: 975074
product: 975111
type: Reaction
reversible: false
product: 975135
reactant: 975014

982482
stoichiometry: 1.0
species: 902186
type: SpeciesReference

002304
stoichiometry: 1.0
species: 897261
type: SpeciesReference

933104
stoichiometry: 1.0
species: 883820
type: SpeciesReference

006103
stoichiometry: 1.0
species: 891086
type: SpeciesReference

895048
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Lanosterol_C30H50O
type: Species

915899
stoichiometry: 1.0
species: 898032
type: SpeciesReference

942680
stoichiometry: 1.0
species: 895314
type: SpeciesReference

960775
stoichiometry: 1.0
species: 890083
type: SpeciesReference

957005
stoichiometry: 1.0
species: 902944
type: SpeciesReference

901537
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Sulfite_O3S
type: Species

955376
stoichiometry: 1.0
species: 880123
type: SpeciesReference

968328
stoichiometry: 1.0
species: 892741
type: SpeciesReference

920939
stoichiometry: 1.0
species: 888816
type: SpeciesReference

995805
stoichiometry: 1.0
species: 880462
type: SpeciesReference

004064
stoichiometry: 2.0
species: 893538
type: SpeciesReference

007627
stoichiometry: 1.0
species: 890155
type: SpeciesReference

004473
stoichiometry: 1.0
species: 891483
type: SpeciesReference

921892
stoichiometry: 1.0
species: 891591
type: SpeciesReference

956920
stoichiometry: 1.0
species: 898466
type: SpeciesReference

968787
stoichiometry: 2.0
species: 897636
type: SpeciesReference

998802
stoichiometry: 1.0
species: 894566
type: SpeciesReference

902788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Thiamin triphosphate_C12H16N4O10P3S
type: Species

900967
reversible: false
notes: R_SMS subsystem: Sphingolipid Metabolism R_SMS equation: [c] : crm_hs + pchol_hs --> dag_hs + sphmyln_hs
is: ENSPTRG00000002502.2
type: Reaction
reactant: 912723
reactant: 912711
fast: false
product: 912747
product: 912735
name: Sphingomyelin synthase (homo sapiens)

958537
stoichiometry: 1.0
species: 881282
type: SpeciesReference

912941
stoichiometry: 1.0
species: 888115
type: SpeciesReference

924958
stoichiometry: 1.0
species: 898032
type: SpeciesReference

967702
stoichiometry: 2.0
species: 899831
type: SpeciesReference

996255
stoichiometry: 1.0
species: 889166
type: SpeciesReference

914088
stoichiometry: 1.0
species: 884427
type: SpeciesReference

899795
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Diphosphate_HO7P2
type: Species

882054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: S-Adenosyl-L-methionine_C15H23N6O5S
type: Species

911891
is: http://identifiers.org/ec-code/4.1.1.37
fast: false
notes: R_UPPDC1 subsystem: Heme Biosynthesis R_UPPDC1 equation: [c] : (4) h + uppg3 --> (4) co2 + cpppg3
product: 008743
reactant: 008731
name: uroporphyrinogen decarboxylase (uroporphyrinogen III)
reactant: 008719
reversible: false
product: 008755
is: ENSPTRG00000000668.5
type: Reaction

925923
stoichiometry: 1.0
species: 879282
type: SpeciesReference

963384
stoichiometry: 1.0
species: 897576
type: SpeciesReference

964412
stoichiometry: 1.0
species: 903440
type: SpeciesReference

994974
stoichiometry: 1.0
species: 887473
type: SpeciesReference

944520
stoichiometry: 3.0
species: 895883
type: SpeciesReference

909614
stoichiometry: 2.0
species: 891664
type: SpeciesReference

892571
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 5_C67H97N4O86S10
type: Species

895737
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Lysine_C6H15N2O2
type: Species

927985
stoichiometry: 1.0
species: 891591
type: SpeciesReference

007374
stoichiometry: 1.0
species: 877384
type: SpeciesReference

988000
stoichiometry: 2.0
species: 891591
type: SpeciesReference

899602
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Phosphate_HO4P
type: Species

882359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _20alpha-Hydroxyprogesterone_C21H32O2
type: Species

891905
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Hexadecenoyl-CoA (n-C16:1CoA)_C37H60N7O17P3S
type: Species

989244
stoichiometry: 1.0
species: 882396
type: SpeciesReference

933600
stoichiometry: 1.0
species: 889238
type: SpeciesReference

986350
stoichiometry: 2.0
species: 897516
type: SpeciesReference

914657
stoichiometry: 1.0
species: 891134
type: SpeciesReference

996327
stoichiometry: 1.0
species: 900376
type: SpeciesReference

949689
stoichiometry: 1.0
species: 886913
type: SpeciesReference

877444
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3,4-Dihydroxymandelate_C8H7O5
type: Species

934914
stoichiometry: 1.0
species: 897225
type: SpeciesReference

008184
stoichiometry: 1.0
species: 883130
type: SpeciesReference

917610
stoichiometry: 3.0
species: 898032
type: SpeciesReference

910774
product: 996678
reactant: 996666
notes: R_ALAR subsystem: Alanine and Aspartate Metabolism R_ALAR equation: [c] : ala-L <==> ala-D
is: ENSPTRG00000020160.2
is: http://identifiers.org/ec-code/5.1.1.1
fast: false
reversible: true
name: alanine racemase
type: Reaction

911890
stoichiometry: 1.0
species: 903488
type: SpeciesReference

959355
stoichiometry: 1.0
species: 890578
type: SpeciesReference

908660
type: Reaction
product: 980052
reactant: 980004
fast: false
reversible: true
is: ENSPTRG00000008230.3
reactant: 980016
name: _11-beta-hydroxysteroid dehydrogenase type 2
notes: R_HSD11B2r subsystem: Steroid Metabolism R_HSD11B2r equation: [r] : cortsn + h + nadh <==> crtsl + nad
reactant: 980028
product: 980040

933965
stoichiometry: 1.0
species: 890698
type: SpeciesReference

879222
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

000482
stoichiometry: 1.0
species: 878932
type: SpeciesReference

009537
stoichiometry: 1.0
species: 891507
type: SpeciesReference

912106
stoichiometry: 1.0
species: 900812
type: SpeciesReference

008875
stoichiometry: 1.0
species: 903452
type: SpeciesReference

992777
stoichiometry: 1.0
species: 898032
type: SpeciesReference

903429
notes: R_SELNPS subsystem: Selenoamino acid metabolism R_SELNPS equation: [c] : atp + h2o + seln --> amp + pi + selnp
fast: false
product: 932223
type: Reaction
is: ENSPTRG00000002303.5
reversible: false
reactant: 932211
reactant: 932186
product: 932235
is: http://identifiers.org/ec-code/2.7.9.3
product: 932247
name: Selenophosphate synthase
reactant: 932198

900412
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Prostaglandin H2_C20H31O5
type: Species

916682
stoichiometry: 1.0
species: 886949
type: SpeciesReference

900969
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Retinoate_C20H27O2
type: Species

961330
stoichiometry: 1.0
species: 882090
type: SpeciesReference

006565
stoichiometry: 5.0
species: 881258
type: SpeciesReference

915609
stoichiometry: 1.0
species: 897516
type: SpeciesReference

884874
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 3_C31H48NO32S2
type: Species

948603
stoichiometry: 1.0
species: 882637
type: SpeciesReference

007942
stoichiometry: 1.0
species: 888418
type: SpeciesReference

984941
stoichiometry: 1.0
species: 885550
type: SpeciesReference

879330
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _6-Phospho-D-gluconate_C6H10O10P
type: Species

896427
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: D-Mannose_C6H12O6
type: Species

924558
stoichiometry: 2.0
species: 903452
type: SpeciesReference

973892
stoichiometry: 2.0
species: 897467
type: SpeciesReference

964862
stoichiometry: 1.0
species: 881499
type: SpeciesReference

971889
stoichiometry: 1.0
species: 894639
type: SpeciesReference

905933
is: ENSPTRG00000007292.4
notes: R_PPCDC subsystem: CoA Biosynthesis R_PPCDC equation: [c] : 4ppcys + h --> co2 + pan4p
product: 954107
reactant: 954071
type: Reaction
is: http://identifiers.org/ec-code/4.1.1.36
name: phosphopantothenoylcysteine decarboxylase
fast: false
product: 954095
reactant: 954083
reversible: false

943776
stoichiometry: 1.0
species: 889358
type: SpeciesReference

988494
stoichiometry: 1.0
species: 897516
type: SpeciesReference

966733
stoichiometry: 6.0
species: 897443
type: SpeciesReference

937665
stoichiometry: 3.0
species: 891664
type: SpeciesReference

954251
stoichiometry: 1.0
species: 891483
type: SpeciesReference

005321
stoichiometry: 6.0
species: 897516
type: SpeciesReference

922359
stoichiometry: 1.0
species: 882685
type: SpeciesReference

936182
stoichiometry: 2.0
species: 891640
type: SpeciesReference

967810
stoichiometry: 1.0
species: 886528
type: SpeciesReference

986253
stoichiometry: 1.0
species: 877480
type: SpeciesReference

935757
stoichiometry: 1.0
species: 886142
type: SpeciesReference

929504
stoichiometry: 1.0
species: 879005
type: SpeciesReference

993598
stoichiometry: 1.0
species: 881198
type: SpeciesReference

979401
stoichiometry: 1.0
species: 887156
type: SpeciesReference

915452
stoichiometry: 1.0
species: 882877
type: SpeciesReference

887606
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dUDP_C9H11N2O11P2
type: Species

980114
stoichiometry: 3.0
species: 891604
type: SpeciesReference

888261
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Ethanolamine phosphate_C2H7NO4P
type: Species

912108
is: http://identifiers.org/ec-code/3.5.1.6
reactant: 010641
type: Reaction
fast: false
product: 010702
product: 010714
notes: R_BUP2 subsystem: Pyrimidine Catabolism R_BUP2 equation: [c] : 3uib + (2) h + h2o --> 3aib-D + co2 + nh4 R_UPPN subsystem: Pyrimidine Catabolism R_UPPN equation: [c] : cala + (2) h + h2o --> ala-B + co2 + nh4
is: ENSPTRG00000014174.3
product: 010690
reversible: false
reactant: 010666
reactant: 010678
product: 010726
reactant: 010654

992341
stoichiometry: 1.0
species: 893223
type: SpeciesReference

963951
stoichiometry: 1.0
species: 880317
type: SpeciesReference

898346
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Octadecynoyl-ACP (n-C18:2ACP)_C29H51N2O8PRS
type: Species

922243
stoichiometry: 1.0
species: 891302
type: SpeciesReference

898285
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Octadecanoyl-ACP (n-C18:0ACP)_C29H55N2O8PRS
type: Species

922613
stoichiometry: 1.0
species: 881764
type: SpeciesReference

998561
stoichiometry: 1.0
species: 894261
type: SpeciesReference

941348
stoichiometry: 1.0
species: 895387
type: SpeciesReference

955400
stoichiometry: 1.0
species: 895834
type: SpeciesReference

905030
stoichiometry: 14.0
species: 891483
type: SpeciesReference

919378
stoichiometry: 1.0
species: 897528
type: SpeciesReference

896257
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Malate_C4H4O5
type: Species

880812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)3 (Glc)1 (GlcNAc)3 (Cer)1_C66H115N4O37FULLRCO
type: Species

961897
stoichiometry: 1.0
species: 897273
type: SpeciesReference

907195
stoichiometry: 4.0
species: 903452
type: SpeciesReference

883251
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cervonyl coenzyme A_C43H62N7O17P3S
type: Species

991533
stoichiometry: 1.0
species: 902258
type: SpeciesReference

885514
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: CTP_C9H12N3O14P3
type: Species

906108
stoichiometry: 1.0
species: 890470
type: SpeciesReference

944641
stoichiometry: 1.0
species: 895980
type: SpeciesReference

940804
stoichiometry: 1.0
species: 883022
type: SpeciesReference

959095
stoichiometry: 1.0
species: 900678
type: SpeciesReference

951503
stoichiometry: 1.0
species: 899166
type: SpeciesReference

970202
stoichiometry: 1.0
species: 896752
type: SpeciesReference

961174
stoichiometry: 1.0
species: 893030
type: SpeciesReference

972142
stoichiometry: 1.0
species: 894771
type: SpeciesReference

891194
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO
type: Species

003174
stoichiometry: 1.0
species: 886733
type: SpeciesReference

877926
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Methylimidazoleacetic acid_C6H7N2O2
type: Species

914838
stoichiometry: 1.0
species: 891483
type: SpeciesReference

904224
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Xanthosine 5'-phosphate_C10H11N4O9P
type: Species

004101
stoichiometry: 2.0
species: 893936
type: SpeciesReference

966407
stoichiometry: 1.0
species: 902030
type: SpeciesReference

900413
reactant: 908716
product: 908776
product: 908752
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_S23Tg subsystem: O-Glycan Biosynthesis R_S23Tg equation: [g] : T_antigen + cmpacna --> cmp + h + sT_antigen R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1
fast: false
is: ENSPTRG00000020606.5
product: 908728
reactant: 908680
reactant: 908692
type: Reaction
product: 908764
is: http://identifiers.org/ec-code/2.4.99.4
reactant: 908704
reversible: false
product: 908740

921675
stoichiometry: 2.0
species: 884270
type: SpeciesReference

906331
fast: false
notes: R_NRPPHRt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_NRPPHRt4_LPAREN_2_RPAREN_r equation: (2) na1[e] + nrpphr[e] <==> (2) na1[c] + nrpphr[c] R_DOPAt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_DOPAt4_LPAREN_2_RPAREN_r equation: dopa[e] + (2) na1[e] <==> dopa[c] + (2) na1[c]
product: 958429
reversible: true
product: 958417
is: ENSPTRG00000016699.3
reactant: 958393
reactant: 958369
type: Reaction
product: 958405
is: ENSPTRG00000008126.5
reactant: 958381

898997
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2
type: Species

935361
stoichiometry: 10.0
species: 882781
type: SpeciesReference

914221
stoichiometry: 1.0
species: 902042
type: SpeciesReference

952696
stoichiometry: 1.0
species: 891483
type: SpeciesReference

881463
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: adrenyl coenzyme A_C43H66N7O17P3S
type: Species

963006
stoichiometry: 1.0
species: 889142
type: SpeciesReference

956028
stoichiometry: 1.0
species: 903403
type: SpeciesReference

887021
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

911174
stoichiometry: 1.0
species: 894334
type: SpeciesReference

962826
stoichiometry: 1.0
species: 904416
type: SpeciesReference

900751
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Ubiquinone-10_C59H90O4
type: Species

941106
stoichiometry: 1.0
species: 891543
type: SpeciesReference

933322
stoichiometry: 1.0
species: 892909
type: SpeciesReference

921119
stoichiometry: 2.0
species: 896257
type: SpeciesReference

966515
stoichiometry: 1.0
species: 877093
type: SpeciesReference

890662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Glycerol_C3H8O3
type: Species

901103
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: de-Fuc form of PA6_C84H135N6O61X
type: Species

949941
stoichiometry: 1.0
species: 902499
type: SpeciesReference

979955
stoichiometry: 2.0
species: 903572
type: SpeciesReference

952768
stoichiometry: 1.0
species: 891640
type: SpeciesReference

978049
stoichiometry: 1.0
species: 892257
type: SpeciesReference

880087
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: R total carnitine_CO2FULLRC7H14NO2
type: Species

942099
stoichiometry: 1.0
species: 897321
type: SpeciesReference

890928
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GlcNAc-alpha-1,4-Core 1_C22H37N2O15X
type: Species

943900
stoichiometry: 1.0
species: 880486
type: SpeciesReference

940379
stoichiometry: 1.0
species: 885828
type: SpeciesReference

939835
stoichiometry: 1.0
species: 897900
type: SpeciesReference

972662
stoichiometry: 1.0
species: 893852
type: SpeciesReference

905600
stoichiometry: 3.0
species: 891604
type: SpeciesReference

887437
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dTDP_C10H13N2O11P2
type: Species

931728
stoichiometry: 1.0
species: 879775
type: SpeciesReference

950665
stoichiometry: 9.0
species: 885707
type: SpeciesReference

904225
modifier: 938416
modifier: 938331
modifier: 938620
product: 938113
modifier: 938428
modifier: 938500
modifier: 938343
modifier: 938355
modifier: 938633
modifier: 938367
modifier: 938221
product: 938076
modifier: 938645
modifier: 938379
modifier: 938233
modifier: 938657
modifier: 938729
modifier: 938245
modifier: 938440
modifier: 938801
modifier: 938669
reactant: 938003
modifier: 938584
modifier: 938319
modifier: 938257
reversible: false
modifier: 938281
reactant: 937991
modifier: 938596
modifier: 938512
modifier: 938269
modifier: 938608
modifier: 938293
modifier: 938705
modifier: 938524
modifier: 938717
modifier: 938536
notes: R_FACOAL2252 subsystem: Fatty acid activation R_FACOAL2252 equation: [c] : atp + clpnd + coa <==> amp + clpndcoa + ppi R_FACOAL226 subsystem: Fatty acid activation R_FACOAL226 equation: [c] : atp + coa + crvnc <==> amp + c226coa + ppi R_FACOAL1812 subsystem: Fatty acid activation R_FACOAL1812 equation: [c] : atp + coa + vacc <==> amp + ppi + vacccoa R_FACOAL161 subsystem: Fatty acid activation R_FACOAL161 equation: [c] : atp + coa + hdcea <==> amp + hdcoa + ppi R_FACOAL2251 subsystem: Fatty acid activation R_FACOAL2251 equation: [c] : atp + coa + dcsptn1 <==> amp + dcsptn1coa + ppi R_FACOAL180i subsystem: Fatty acid activation R_FACOAL180i equation: [c] : atp + coa + ocdca --> amp + ppi + stcoa R_FACOAL260 subsystem: Fatty acid activation R_FACOAL260 equation: [c] : atp + coa + hexc <==> amp + hexccoa + ppi R_FACOAL241 subsystem: Fatty acid activation R_FACOAL241 equation: [c] : atp + coa + nrvnc <==> amp + nrvnccoa + ppi R_FACOAL181i subsystem: Fatty acid activation R_FACOAL181i equation: [c] : atp + coa + ocdcea --> amp + odecoa + ppi R_FACOAL245_2 subsystem: Fatty acid activation R_FACOAL245_2 equation: [c] : atp + coa + tetpent3 <==> amp + ppi + tetpent3coa R_FACOAL245_1 subsystem: Fatty acid activation R_FACOAL245_1 equation: [c] : atp + coa + tetpent6 <==> amp + ppi + tetpent6coa R_FACOAL2042 subsystem: Fatty acid activation R_FACOAL2042 equation: [c] : atp + coa + eicostet <==> amp + eicostetcoa + ppi R_FACOAL224 subsystem: Fatty acid activation R_FACOAL224 equation: [c] : adrn + atp + coa <==> adrncoa + amp + ppi R_FACOAL246_1 subsystem: Fatty acid activation R_FACOAL246_1 equation: [c] : atp + coa + tethex3 <==> amp + ppi + tethex3coa R_FACOAL204 subsystem: Fatty acid activation R_FACOAL204 equation: [c] : arachd + atp + coa <==> amp + arachdcoa + ppi R_FACOAL1831 subsystem: Fatty acid activation R_FACOAL1831 equation: [c] : atp + coa + lnlncg <==> amp + lnlncgcoa + ppi R_FACOAL203 subsystem: Fatty acid activation R_FACOAL203 equation: [c] : atp + coa + dln…
modifier: 938548
modifier: 938681
is: http://identifiers.org/ec-code/6.2.1.3
modifier: 938693
reactant: 938028
product: 938064
type: Reaction
modifier: 938149
product: 938125
modifier: 938391
modifier: 938185
modifier: 938560
product: 938100
modifier: 938197
modifier: 938572
modifier: 938765
is: ENSPTRG00000016644.4
product: 938088
modifier: 938777
reactant: 938040
modifier: 938137
modifier: 938452
modifier: 938161
modifier: 938789
reactant: 938052
modifier: 938464
fast: false
modifier: 938173
modifier: 938741
modifier: 938476
modifier: 938209
modifier: 938306
modifier: 938753
modifier: 938488
modifier: 938404
reactant: 938016

004317
stoichiometry: 2.0
species: 903824
type: SpeciesReference

941456
stoichiometry: 1.0
species: 889238
type: SpeciesReference

938088
stoichiometry: 1.0
species: 899626
type: SpeciesReference

905031
product: 945145
fast: false
notes: R_S2T4g subsystem: Chondroitin / heparan sulfate biosynthesis R_S2T4g equation: [g] : hs_pre11 + (2) paps --> (2) h + hs_pre12 + (2) pap
product: 945133
reactant: 945109
is: ENSPTRG00000000927.5
reactant: 945097
reversible: false
name: uronyl 2-sulfotransferase, Golgi
product: 945121
type: Reaction

918061
stoichiometry: 4.0
species: 891591
type: SpeciesReference

902787
is: http://identifiers.org/ec-code/2.5.1.17
modifier: 927344
reactant: 927272
modifier: 927332
is: ENSPTRG00000016486.4
modifier: 927320
reversible: false
modifier: 927308
notes: R_CBLATm subsystem: Vitamin B12 Metabolism R_CBLATm equation: [m] : atp + cbl1 + h <==> adocbl + pppi R_CBL2tm subsystem: Transport, Mitochondrial R_CBL2tm equation: cbl2[c] --> cbl2[m]
product: 927284
fast: false
type: Reaction
modifier: 927296

005068
stoichiometry: 1.0
species: 891664
type: SpeciesReference

914378
stoichiometry: 1.0
species: 885490
type: SpeciesReference

007084
stoichiometry: 1.0
species: 882493
type: SpeciesReference

909760
stoichiometry: 1.0
species: 877963
type: SpeciesReference

983868
stoichiometry: 1.0
species: 893175
type: SpeciesReference

002981
stoichiometry: 35.0
species: 897431
type: SpeciesReference

903427
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Tyrosine_C9H11NO3
type: Species

928998
stoichiometry: 1.0
species: 896390
type: SpeciesReference

979269
stoichiometry: 3.0
species: 881258
type: SpeciesReference

907196
reactant: 963927
reversible: false
is: ENSPTRG00000005998.4
notes: R_CITL subsystem: Citric Acid Cycle R_CITL equation: [c] : cit --> ac + oaa
product: 963951
product: 963939
fast: false
name: Citrate lyase
is: http://identifiers.org/ec-code/4.1.3.6
type: Reaction

943378
stoichiometry: 1.0
species: 899069
type: SpeciesReference

985197
stoichiometry: 4.0
species: 903560
type: SpeciesReference

946882
stoichiometry: 1.0
species: 901066
type: SpeciesReference

001039
stoichiometry: 2.0
species: 884391
type: SpeciesReference

923037
stoichiometry: 1.0
species: 894152
type: SpeciesReference

945073
stoichiometry: 1.0
species: 880317
type: SpeciesReference

962126
stoichiometry: 1.0
species: 903970
type: SpeciesReference

994321
stoichiometry: 1.0
species: 895931
type: SpeciesReference

908159
stoichiometry: 1.0
species: 891591
type: SpeciesReference

881258
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: ADP_C10H12N5O10P2
type: Species

887326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Dopamine_C8H12NO2
type: Species

980004
stoichiometry: 1.0
species: 897419
type: SpeciesReference

905248
type: Reaction
reactant: 946218
product: 946242
is: ENSPTRG00000012742.3
product: 946254
fast: false
product: 946230
reactant: 946206
reactant: 946194
notes: R_MI134PP subsystem: Inositol Phosphate Metabolism R_MI134PP equation: [c] : h2o + mi134p --> mi34p + pi R_MI14PP subsystem: Inositol Phosphate Metabolism R_MI14PP equation: [c] : h2o + mi14p --> mi4p-D + pi
is: http://identifiers.org/ec-code/3.1.3.57
reversible: false

000784
stoichiometry: 18.0
species: 891591
type: SpeciesReference

998670
stoichiometry: 1.0
species: 894879
type: SpeciesReference

952540
stoichiometry: 1.0
species: 881680
type: SpeciesReference

954483
stoichiometry: 1.0
species: 890578
type: SpeciesReference

934373
stoichiometry: 4.0
species: 897407
type: SpeciesReference

908003
product: 972638
is: ENSPTRG00000012741.4
fast: false
product: 972650
reversible: false
is: http://identifiers.org/ec-code/3.1.2.4
product: 972626
notes: R_3HPCOAHYD subsystem: beta-Alanine metabolism R_3HPCOAHYD equation: [c] : 3hpcoa + h2o --> 3hpp + coa + h
name: _3-hydroxyisobutyryl-Coenzyme A hydrolase
type: Reaction
reactant: 972601
reactant: 972613

930508
stoichiometry: 1.0
species: 901293
type: SpeciesReference

968196
stoichiometry: 1.0
species: 892753
type: SpeciesReference

003800
stoichiometry: 1.0
species: 893731
type: SpeciesReference

942521
stoichiometry: 1.0
species: 892037
type: SpeciesReference

991244
stoichiometry: 2.0
species: 884270
type: SpeciesReference

903317
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: tetradecanoate (n-C14:0)_C14H27O2
type: Species

896837
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1D-myo-Inositol 1,4-bisphosphate_C6H10O12P2
type: Species

919221
stoichiometry: 1.0
species: 882384
type: SpeciesReference

978895
stoichiometry: 2.0
species: 882090
type: SpeciesReference

936436
stoichiometry: 1.0
species: 881885
type: SpeciesReference

928672
stoichiometry: 1.0
species: 903716
type: SpeciesReference

896148
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: (alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1780H2928N20O620P20
type: Species

004257
stoichiometry: 1.0
species: 887655
type: SpeciesReference

996534
stoichiometry: 1.0
species: 887715
type: SpeciesReference

898840
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phosphatidylinositol 4,5-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2
type: Species

904115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Vitamin D2_C28H44O
type: Species

983639
stoichiometry: 1.0
species: 880547
type: SpeciesReference

969293
stoichiometry: 5.0
species: 891616
type: SpeciesReference

882625
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Arginine_C6H15N4O2
type: Species

939727
stoichiometry: 1.0
species: 891519
type: SpeciesReference

895895
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: (alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog_C1540H2528N20O420P20
type: Species

911026
type: Reaction
reactant: 999079
product: 999151
product: 999139
product: 999115
reactant: 999103
notes: R_ST6GALNAC62 subsystem: Sphingolipid Metabolism R_ST6GALNAC62 equation: [g] : cmpacna + gt1b_hs --> cmp + gq1balpha_hs + h R_ST6GALNAC61 subsystem: Sphingolipid Metabolism R_ST6GALNAC61 equation: [g] : cmpacna + gd1a_hs --> cmp + gt1alpha_hs + h R_ST6GALNAC31 subsystem: Sphingolipid Metabolism R_ST6GALNAC31 equation: [g] : cmpacna + gm1b_hs --> cmp + gd1alpha_hs + h
reactant: 999091
product: 999127
reactant: 999067
product: 999163
reversible: false
fast: false
is: ENSPTRG00000021403.4

905938
stoichiometry: 1.0
species: 899009
type: SpeciesReference

908668
stoichiometry: 2.0
species: 897407
type: SpeciesReference

944965
stoichiometry: 1.0
species: 878691
type: SpeciesReference

976272
stoichiometry: 2.0
species: 891483
type: SpeciesReference

879763
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Protein N6,N6-dimethyl-L-lysine_C2H7X
type: Species

898068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: O2_O2
type: Species

005179
stoichiometry: 5.0
species: 899530
type: SpeciesReference

880704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Type IA glycolipid_C58H102N3O31FULLRCO
type: Species

889923
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GD1b (homo sapiens)_C66H111N4O38FULLRCO
type: Species

969148
stoichiometry: 2.0
species: 881222
type: SpeciesReference

949120
stoichiometry: 1.0
species: 894128
type: SpeciesReference

947966
stoichiometry: 1.0
species: 895713
type: SpeciesReference

906894
stoichiometry: 1.0
species: 882200
type: SpeciesReference

960209
stoichiometry: 1.0
species: 884391
type: SpeciesReference

908001
stoichiometry: 2.0
species: 897371
type: SpeciesReference

909765
product: 989061
product: 989013
fast: false
product: 989049
reactant: 988977
product: 989025
product: 989001
reactant: 988917
reactant: 988989
reactant: 988953
is: http://identifiers.org/ec-code/3.5.4.14
reactant: 988929
reactant: 988965
is: http://identifiers.org/ec-code/3.5.4.5
reactant: 988905
is: ENSPTRG00000004640.4
reactant: 988941
type: Reaction
product: 989037
notes: R_DCYTD subsystem: Pyrimidine Catabolism R_DCYTD equation: [c] : dcyt + h + h2o --> duri + nh4 R_CYTDn subsystem: Nucleotides R_CYTDn equation: [n] : cytd + h + h2o --> nh4 + uri R_DCYTDn subsystem: Nucleotides R_DCYTDn equation: [n] : dcyt + h + h2o --> duri + nh4 R_CYTD subsystem: Pyrimidine Catabolism R_CYTD equation: [c] : cytd + h + h2o --> nh4 + uri
reversible: false

962718
stoichiometry: 2.0
species: 898056
type: SpeciesReference

950556
stoichiometry: 9.0
species: 885719
type: SpeciesReference

884632
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: ceramide (homo sapiens)_C18H36NO2FULLRCO
type: Species

951175
stoichiometry: 1.0
species: 895737
type: SpeciesReference

972553
stoichiometry: 1.0
species: 900665
type: SpeciesReference

904116
reversible: true
product: 937024
product: 937012
reactant: 937000
type: Reaction
reactant: 936988
notes: R_G6PDH2r subsystem: Pentose Phosphate Pathway R_G6PDH2r equation: [c] : g6p + nadp <==> 6pgl + h + nadph
product: 937036
name: glucose 6-phosphate dehydrogenase
is: http://identifiers.org/ec-code/1.1.1.49
is: ENSPTRG00000022443.5
fast: false

924124
stoichiometry: 16.0
species: 891495
type: SpeciesReference

944857
stoichiometry: 1.0
species: 892558
type: SpeciesReference

994213
stoichiometry: 1.0
species: 881258
type: SpeciesReference

886769
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: dIDP_C10H11N4O10P2
type: Species

932391
stoichiometry: 2.0
species: 891483
type: SpeciesReference

907846
is: ENSPTRG00000004368.2
name: hydroxymethylbilane synthase
product: 970977
product: 970964
is: http://identifiers.org/ec-code/4.3.1.8
reactant: 970939
notes: R_HMBS subsystem: Heme Biosynthesis R_HMBS equation: [c] : h2o + (4) ppbng --> hmbil + (4) nh4
type: Reaction
reactant: 970951
reversible: false
fast: false

002871
stoichiometry: 1.0
species: 891664
type: SpeciesReference

882200
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Androsterone_C19H30O2
type: Species

958309
stoichiometry: 1.0
species: 882745
type: SpeciesReference

914946
stoichiometry: 1.0
species: 887266
type: SpeciesReference

005923
stoichiometry: 1.0
species: 901777
type: SpeciesReference

987518
stoichiometry: 1.0
species: 896052
type: SpeciesReference

921458
stoichiometry: 1.0
species: 881909
type: SpeciesReference

906895
reactant: 962452
type: Reaction
product: 962499
reactant: 962463
reactant: 962475
product: 962488
is: ENSPTRG00000016351.5
notes: R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad
reversible: true
name: _3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) (mitochondria)
fast: false
is: http://identifiers.org/ec-code/1.1.1.35

900642
reactant: 910740
product: 910764
product: 910788
is: ENSPTRG00000003423.4
is: ENSPTRG00000003422.5
modifier: 910849
modifier: 910897
fast: false
modifier: 910885
reactant: 910704
modifier: 910812
product: 910752
reactant: 910680
is: http://identifiers.org/ec-code/1.2.3.5
product: 910800
is: ENSPTRG00000004762.3
modifier: 910837
reactant: 910728
is: ENSPTRG00000007125.4
product: 910776
modifier: 910873
modifier: 910825
reactant: 910716
type: Reaction
reactant: 910692
is: http://identifiers.org/ec-code/1.1.1.27
modifier: 910861
reversible: false
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa
modifier: 910909

911170
product: 000201
reactant: 000188
notes: R_PHEMEt subsystem: Transport, Extracellular R_PHEMEt equation: pheme[e] --> pheme[c]
is: ENSPTRG00000008918.4
fast: false
reversible: false
name: heme transport
type: Reaction

892461
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 20_C45H68N2O43S2
type: Species

936580
stoichiometry: 1.0
species: 902728
type: SpeciesReference

881788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _2-Oxoglutarate_C5H4O5
type: Species

970310
stoichiometry: 1.0
species: 897467
type: SpeciesReference

931836
stoichiometry: 1.0
species: 890264
type: SpeciesReference

978870
stoichiometry: 1.0
species: 899626
type: SpeciesReference

954593
stoichiometry: 1.0
species: 882769
type: SpeciesReference

895302
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

978157
stoichiometry: 1.0
species: 886937
type: SpeciesReference

907845
stoichiometry: 22.0
species: 891471
type: SpeciesReference

951611
stoichiometry: 2.0
species: 883338
type: SpeciesReference

907087
stoichiometry: 1.0
species: 889851
type: SpeciesReference

995380
stoichiometry: 1.0
species: 899771
type: SpeciesReference

965462
stoichiometry: 1.0
species: 903440
type: SpeciesReference

957379
stoichiometry: 2.0
species: 880414
type: SpeciesReference

889178
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: glucosyl-(alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C64H107N2O50X
type: Species

961787
stoichiometry: 1.0
species: 896752
type: SpeciesReference

004533
stoichiometry: 10.0
species: 897321
type: SpeciesReference

960075
stoichiometry: 1.0
species: 899130
type: SpeciesReference

905188
is: http://identifiers.org/ec-code/3.2.1.1
reactant: 945712
product: 945797
reactant: 945737
is: ENSPTRG00000010796.2
product: 945761
reversible: false
reactant: 945688
reactant: 945700
fast: false
product: 945785
product: 945749
type: Reaction
notes: R_AMY1e subsystem: Starch and Sucrose Metabolism R_AMY1e equation: [e] : (8) h2o + strch1 --> (8) glc-D + strch2 R_CYSTSERex subsystem: Transport, Extracellular R_CYSTSERex equation: Lcystin[e] + ser-L[c] --> Lcystin[c] + ser-L[e] R_AMY2e subsystem: Starch and Sucrose Metabolism R_AMY2e equation: [e] : glygn2 + (8) h2o --> (8) glc-D + glygn4
reactant: 945725
product: 945773

979847
stoichiometry: 1.0
species: 880123
type: SpeciesReference

984388
stoichiometry: 1.0
species: 899069
type: SpeciesReference

891278
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Reduced glutathione_C10H16N3O6S
type: Species

918760
stoichiometry: 2.0
species: 902716
type: SpeciesReference

900641
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Pyridoxal 5'-phosphate_C8H8NO6P
type: Species

948014
stoichiometry: 1.0
species: 901826
type: SpeciesReference

970046
stoichiometry: 1.0
species: 891604
type: SpeciesReference

929808
stoichiometry: 1.0
species: 889358
type: SpeciesReference

954362
stoichiometry: 1.0
species: 893960
type: SpeciesReference

942957
stoichiometry: 1.0
species: 891242
type: SpeciesReference

952467
stoichiometry: 1.0
species: 887278
type: SpeciesReference

010641
stoichiometry: 1.0
species: 883362
type: SpeciesReference

903872
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Urea_CH4N2O
type: Species

917502
stoichiometry: 1.0
species: 887107
type: SpeciesReference

919136
stoichiometry: 1.0
species: 891640
type: SpeciesReference

944411
stoichiometry: 1.0
species: 896088
type: SpeciesReference

999079
stoichiometry: 3.0
species: 884270
type: SpeciesReference

899799
reactant: 904885
type: Reaction
is: http://identifiers.org/ec-code/3.1.6.13
product: 904921
reversible: false
fast: false
is: ENSPTRG00000022355.4
product: 904933
reactant: 904849
notes: R_S2TASE2ly subsystem: Heparan sulfate degradation R_S2TASE2ly equation: [l] : h2o + hs_deg21 --> h + hs_deg22 + so4 R_S2TASE1ly subsystem: Heparan sulfate degradation R_S2TASE1ly equation: [l] : h2o + hs_deg15 --> h + hs_deg16 + so4 R_S2TASE3ly subsystem: Chondroitin sulfate degradation R_S2TASE3ly equation: [l] : cs_b_deg2 + h2o --> cs_b_deg3 + h + so4
product: 904945
reactant: 904861
reactant: 904873
product: 904909
is: ENSPTRG00000022356.2
product: 904897

969426
stoichiometry: 2.0
species: 885961
type: SpeciesReference

986143
stoichiometry: 1.0
species: 877890
type: SpeciesReference

885949
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: dCMP_C9H12N3O7P
type: Species

001869
stoichiometry: 1.0
species: 903137
type: SpeciesReference

970624
stoichiometry: 1.0
species: 877432
type: SpeciesReference

956751
stoichiometry: 1.0
species: 881487
type: SpeciesReference

975014
stoichiometry: 1.0
species: 900340
type: SpeciesReference

960823
stoichiometry: 1.0
species: 899250
type: SpeciesReference

975462
stoichiometry: 2.0
species: 884222
type: SpeciesReference

968678
stoichiometry: 1.0
species: 895112
type: SpeciesReference

880195
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Tn antigen_C8H14NO5X
type: Species

942255
stoichiometry: 1.0
species: 881354
type: SpeciesReference

937557
stoichiometry: 1.0
species: 902812
type: SpeciesReference

992620
stoichiometry: 1.0
species: 891495
type: SpeciesReference

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stoichiometry: 1.0
species: 882805
type: SpeciesReference

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stoichiometry: 3.0
species: 882090
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 28_C213H341N15O176S8X
type: Species

886396
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dGTP_C10H12N5O13P3
type: Species

963494
stoichiometry: 30.0
species: 897273
type: SpeciesReference

980608
stoichiometry: 1.0
species: 898852
type: SpeciesReference

946218
stoichiometry: 1.0
species: 896837
type: SpeciesReference

887169
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10
type: Species

955980
stoichiometry: 1.0
species: 891579
type: SpeciesReference

933757
stoichiometry: 1.0
species: 898840
type: SpeciesReference

949833
stoichiometry: 1.0
species: 901814
type: SpeciesReference

988156
stoichiometry: 3.0
species: 881258
type: SpeciesReference

921229
stoichiometry: 1.0
species: 899783
type: SpeciesReference

984712
stoichiometry: 1.0
species: 896655
type: SpeciesReference

986567
stoichiometry: 1.0
species: 898032
type: SpeciesReference

881571
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Etiocholan-3alpha-ol-17-one 3-glucuronide_C25H38O8
type: Species

902354
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: tetracosapentaenoyl coenzyme A, n-3_C45H68N7O17P3S
type: Species

009429
stoichiometry: 3.0
species: 881897
type: SpeciesReference

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stoichiometry: 1.0
species: 882709
type: SpeciesReference

971998
stoichiometry: 1.0
species: 894407
type: SpeciesReference

986783
stoichiometry: 1.0
species: 889286
type: SpeciesReference

006819
stoichiometry: 1.0
species: 900508
type: SpeciesReference

888696
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Formate_CH1O2
type: Species

919897
stoichiometry: 1.0
species: 898032
type: SpeciesReference

948712
stoichiometry: 1.0
species: 889430
type: SpeciesReference

935649
stoichiometry: 2.0
species: 891591
type: SpeciesReference

983784
stoichiometry: 1.0
species: 880535
type: SpeciesReference

934709
stoichiometry: 1.0
species: 890386
type: SpeciesReference

945278
stoichiometry: 2.0
species: 891640
type: SpeciesReference

996750
stoichiometry: 2.0
species: 881740
type: SpeciesReference

909070
stoichiometry: 1.0
species: 902090
type: SpeciesReference

916573
stoichiometry: 1.0
species: 903353
type: SpeciesReference

884983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate B (IdoA2S-GalNAc4s), precursor 5_C45H66N2O45S3X
type: Species

900521
product: 909529
product: 909541
name: Malonyl-CoA-ACP transacylase, mitochondrial
type: Reaction
reactant: 909517
reactant: 909505
fast: false
is: http://identifiers.org/ec-code/2.3.1.39
reversible: true
notes: R_MCOATAm subsystem: Fatty Acid Metabolism R_MCOATAm equation: [m] : ACP + malcoa <==> coa + malACP
is: ENSPTRG00000014468.4

913193
stoichiometry: 1.0
species: 890518
type: SpeciesReference

925368
stoichiometry: 1.0
species: 903620
type: SpeciesReference

008463
stoichiometry: 1.0
species: 880728
type: SpeciesReference

876983
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1-Methylpyrrolinium_C5H10N
type: Species

001245
stoichiometry: 2.0
species: 893418
type: SpeciesReference

993489
stoichiometry: 1.0
species: 881222
type: SpeciesReference

979558
stoichiometry: 4.0
species: 881258
type: SpeciesReference

891086
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Guanosine_C10H13N5O5
type: Species

994866
stoichiometry: 1.0
species: 895713
type: SpeciesReference

887715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dUTP_C9H11N2O14P3
type: Species

936291
stoichiometry: 1.0
species: 897371
type: SpeciesReference

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stoichiometry: 1.0
species: 892765
type: SpeciesReference

896535
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Methanol_CH4O1
type: Species

959107
stoichiometry: 14.0
species: 897321
type: SpeciesReference

902355
fast: false
reversible: false
is: ENSPTRG00000004352.4
reactant: 923751
type: Reaction
is: http://identifiers.org/ec-code/3.2.1.28
reactant: 923739
product: 923763
name: alpha,alpha-trehalase
notes: R_TREHe subsystem: Starch and Sucrose Metabolism R_TREHe equation: [e] : h2o + tre --> (2) glc-D

877601
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-3-Amino-isobutanoate_C4H9NO2
type: Species

943041
stoichiometry: 2.0
species: 891278
type: SpeciesReference

924848
stoichiometry: 1.0
species: 884222
type: SpeciesReference

897201
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: reducing GlcNAc removed form of n2m2nmasn (w/o peptide)_C50H84N4O36
type: Species

900859
product: 911818
product: 911854
is: ENSPTRG00000010676.4
product: 911842
type: Reaction
reactant: 911782
reversible: true
reactant: 911806
fast: false
reactant: 911770
reactant: 911794
notes: R_FATP3t subsystem: Transport, Extracellular R_FATP3t equation: na1[c] + ocdca[c] <==> na1[e] + ocdca[e] R_FATP1t subsystem: Transport, Extracellular R_FATP1t equation: hdca[c] + na1[c] <==> hdca[e] + na1[e] R_FATP2t subsystem: Transport, Extracellular R_FATP2t equation: na1[c] + ocdcea[c] <==> na1[e] + ocdcea[e]
product: 911830

977796
stoichiometry: 1.0
species: 879883
type: SpeciesReference

900520
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: pentadecanoate_C15H29O2
type: Species

981191
stoichiometry: 1.0
species: 882359
type: SpeciesReference

000627
stoichiometry: 18.0
species: 881282
type: SpeciesReference

909748
stoichiometry: 1.0
species: 876911
type: SpeciesReference

903885
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Urea_CH4N2O
type: Species

881559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _3alpha-Hydroxy-5beta-androstan-17-one_C19H30O2
type: Species

890940
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GlcNAc-alpha-1,4-Core 2_C30H50N3O20X
type: Species

957149
stoichiometry: 5.0
species: 899530
type: SpeciesReference

879559
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: acyl carrier protein_C11H21N2O7PRS
type: Species

915753
stoichiometry: 1.0
species: 898032
type: SpeciesReference

909825
product: 990281
reactant: 990015
reactant: 989834
product: 990402
product: 990415
is: http://identifiers.org/ec-code/2.4.1.149
product: 990389
reactant: 989979
product: 990221
fast: false
product: 990233
product: 990111
reactant: 989678
product: 990087
type: Reaction
product: 990245
product: 990123
reactant: 989642
product: 990305
reactant: 989846
reactant: 989618
reactant: 989726
product: 990317
reactant: 989894
reactant: 989918
reactant: 989666
product: 990441
reactant: 989991
reactant: 989774
product: 990329
product: 990160
reactant: 989798
reactant: 990003
reactant: 989822
reactant: 989942
product: 990293
reactant: 989702
reactant: 989690
product: 990428
is: ENSPTRG00000010684.3
product: 990467
notes: R_B3GNT37g subsystem: Sphingolipid Metabolism R_B3GNT37g equation: [g] : gm2a_hs + udpgal --> gm1a_hs + h + udp R_B3GNT38g subsystem: Sphingolipid Metabolism R_B3GNT38g equation: [g] : galside_hs + udpgal --> digalside_hs + h + udp R_B3GNT312g subsystem: Blood Group Biosynthesis R_B3GNT312g equation: [g] : acglcgal14acglcgalgluside_hs + udpgal --> galacglcgal14acglcgalgluside_hs + h + udp R_AG13T6g subsystem: Keratan sulfate biosynthesis R_AG13T6g equation: [g] : ksi_pre6 + uacgam --> h + ksi_pre7 + udp R_B3GNT31g subsystem: Sphingolipid Metabolism R_B3GNT31g equation: [g] : thcrm_hs + udpgal --> galthcrm_hs + h + udp R_AG13T17g subsystem: Keratan sulfate biosynthesis R_AG13T17g equation: [g] : ksii_core4_pre4 + uacgam --> h + ksii_core4_pre5 + udp R_B3GNT36g subsystem: Sphingolipid Metabolism R_B3GNT36g equation: [g] : acgal + gbside_hs --> acgbgbside_hs + h2o R_AG13T2g subsystem: Keratan sulfate biosynthesis R_AG13T2g equation: [g] : ksii_core2_pre4 + uacgam --> h + ksii_core2_pre5 + udp R_AG13T5g subsystem: Keratan sulfate biosynthesis R_AG13T5g equation: [g] : ksi_pre3 + uacgam --> h + ksi_pre4 + udp R_B3GNT313g subsystem: Blood Group Biosynthesis R_B3GNT313g equation: [g] : acgalfucgalacglcgal14acglcgalgluside_hs + udpgal --> galacgalfucgalacglcgal14acglcgalgluside_hs + h + udp R_AG13T8g subsystem: Keratan sulfate biosynthesis R_AG13T8g equation: [g] : ksi_pre12 + uacgam --> h + ksi_pre13 + udp R_B3GNT310g subsystem: Blood Group Biosynthesis R_B3GNT310g equation: [g] : acglcgalgluside_hs + udpgal --> gal14acglcgalgluside_hs + h + udp R_AG13T12g subsystem: Keratan sulfate biosynthesis R_AG13T12g equation: [g] : ksi_pre24 + uacgam --> h + ksi_pre25 + udp R_B3GNT33g subsystem: Sphingolipid Metabolism R_B3GNT33g equation: [g] : galgalthcrm_hs + udpgal --> galgalgalthcrm_hs + h + udp R_AG13T1g subsystem: Keratan sulfate biosynthesis R_AG13T1g equation: [g] : ksii_core2_pre2 + uacgam --> h + ksii_core2_pre3 + udp R_B3GNT39g subsystem: Sphingolipid Metabolism R_B3GNT3…
reactant: 990027
product: 990135
product: 990172
reactant: 989882
product: 990353
product: 990039
product: 990184
reactant: 989630
product: 990365
product: 990257
product: 990196
reactant: 989606
product: 990377
reactant: 989714
reversible: false
reactant: 989654
reactant: 989762
product: 990454
reactant: 989738
product: 990341
product: 990051
reactant: 989786
reactant: 989930
reactant: 989906
product: 990063
product: 990099
reactant: 989858
reactant: 989967
product: 990075
product: 990209
reactant: 989954
product: 990269
reactant: 989810
product: 990147
reactant: 989870
reactant: 989750

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stoichiometry: 1.0
species: 877396
type: SpeciesReference

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stoichiometry: 1.0
species: 901390
type: SpeciesReference

912831
stoichiometry: 4.0
species: 891555
type: SpeciesReference

907615
stoichiometry: 1.0
species: 892037
type: SpeciesReference

936279
stoichiometry: 2.0
species: 904392
type: SpeciesReference

943475
stoichiometry: 1.0
species: 892691
type: SpeciesReference

956461
stoichiometry: 1.0
species: 902390
type: SpeciesReference

010369
stoichiometry: 1.0
species: 880317
type: SpeciesReference

907918
name: _3-hydroxybutyryl-CoA dehydratase, mitochondrial
reversible: true
product: 971635
is: http://identifiers.org/ec-code/4.2.1.55
notes: R_3HBCDm subsystem: Butanoate Metabolism R_3HBCDm equation: [m] : b2coa + h2o <==> 3hbcoa-R
type: Reaction
is: ENSPTRG00000000747.4
reactant: 971611
fast: false
reactant: 971623

994539
stoichiometry: 1.0
species: 895992
type: SpeciesReference

995902
stoichiometry: 1.0
species: 888406
type: SpeciesReference

932162
stoichiometry: 1.0
species: 891760
type: SpeciesReference

918857
stoichiometry: 1.0
species: 890458
type: SpeciesReference

881113
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: O-Acetylcarnitine_C9H17NO4
type: Species

002402
stoichiometry: 1.0
species: 890518
type: SpeciesReference

931606
stoichiometry: 1.0
species: 897516
type: SpeciesReference

941552
stoichiometry: 10.0
species: 882781
type: SpeciesReference

999940
stoichiometry: 1.0
species: 891591
type: SpeciesReference

993718
stoichiometry: 1.0
species: 890977
type: SpeciesReference

910642
product: 995975
product: 995987
notes: R_PPPGOm subsystem: Heme Biosynthesis R_PPPGOm equation: [m] : (3) o2 + (2) pppg9 --> (6) h2o + (2) ppp9
reactant: 995963
is: http://identifiers.org/ec-code/1.3.3.4
reversible: false
name: protoporphyrinogen oxidase, mitochondrial
is: ENSPTRG00000001574.5
reactant: 995951
type: Reaction
fast: false

905890
stoichiometry: 1.0
species: 902246
type: SpeciesReference

903886
reactant: 935709
reactant: 935745
product: 935891
is: ENSPTRG00000002315.5
reactant: 935697
product: 935855
product: 935794
reactant: 935770
fast: false
reactant: 935733
notes: R_FA160ACPH subsystem: Fatty Acid Metabolism R_FA160ACPH equation: [c] : h2o + palmACP <==> ACP + h + hdca R_FA181ACPH subsystem: Fatty Acid Metabolism R_FA181ACPH equation: [c] : h2o + octeACP <==> ACP + h + ocdcea R_FA120ACPH subsystem: Fatty Acid Metabolism R_FA120ACPH equation: [c] : ddcaACP + h2o <==> ACP + ddca + h R_FA182ACPH subsystem: Fatty Acid Metabolism R_FA182ACPH equation: [c] : h2o + ocdcyaACP <==> ACP + h + ocdcya R_FA140ACPH subsystem: Fatty Acid Metabolism R_FA140ACPH equation: [c] : h2o + myrsACP <==> ACP + h + ttdca R_FA141ACPH subsystem: Fatty Acid Metabolism R_FA141ACPH equation: [c] : h2o + tdeACP <==> ACP + h + ttdcea R_FA161ACPH subsystem: Fatty Acid Metabolism R_FA161ACPH equation: [c] : h2o + hdeACP <==> ACP + h + hdcea R_FA180ACPH subsystem: Fatty Acid Metabolism R_FA180ACPH equation: [c] : h2o + ocdcaACP <==> ACP + h + ocdca
product: 935879
product: 935843
reactant: 935721
reversible: true
product: 935819
type: Reaction
product: 935903
product: 935806
reactant: 935685
product: 935867
reactant: 935757
product: 935831
reactant: 935782
is: http://identifiers.org/ec-code/3.1.2.14

920297
stoichiometry: 1.0
species: 885212
type: SpeciesReference

007506
stoichiometry: 1.0
species: 889996
type: SpeciesReference

978726
stoichiometry: 1.0
species: 883615
type: SpeciesReference

960678
stoichiometry: 1.0
species: 878727
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 31_C90H148N6O72S2
type: Species

922073
stoichiometry: 1.0
species: 885514
type: SpeciesReference

941760
stoichiometry: 1.0
species: 886420
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _4,4-dimethylzymosterol_C29H48O
type: Species

009803
stoichiometry: 1.0
species: 890952
type: SpeciesReference

993874
stoichiometry: 1.0
species: 890506
type: SpeciesReference

963237
stoichiometry: 1.0
species: 898056
type: SpeciesReference

989097
stoichiometry: 3.0
species: 882781
type: SpeciesReference

925656
stoichiometry: 1.0
species: 882781
type: SpeciesReference

919450
stoichiometry: 1.0
species: 889717
type: SpeciesReference

917127
stoichiometry: 1.0
species: 902438
type: SpeciesReference

906688
stoichiometry: 1.0
species: 883928
type: SpeciesReference

877008
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-1-Pyrroline-3-hydroxy-5-carboxylate_C5H6NO3
type: Species

951380
stoichiometry: 1.0
species: 898840
type: SpeciesReference

899057
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Phosphatidylcholine (homo sapiens)_C8H18NO4PFULLRCO2FULLR2CO2
type: Species

905392
reactant: 948366
is: http://identifiers.org/ec-code/1.3.99.2
fast: false
is: http://identifiers.org/ec-code/1.3.99.3
product: 948466
reactant: 948195
reactant: 948159
reactant: 948269
reactant: 948086
product: 948492
product: 948479
reactant: 948294
reactant: 948245
reversible: false
reactant: 948062
reactant: 948318
reactant: 948219
reactant: 948354
reactant: 948026
type: Reaction
product: 948518
product: 948543
product: 948505
product: 948402
notes: R_FAOXC183806m subsystem: Fatty acid oxidation R_FAOXC183806m equation: [m] : (5) coa + (5) h2o + lnlncgcoa + (5) nad + (2) o2 --> (5) accoa + (5) h + (2) h2o2 + (5) nadh + occoa R_FAOXC161802m subsystem: Fatty acid activation R_FAOXC161802m equation: [m] : (4) coa + (3) fad + (4) h2o + hdd2coa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC160 subsystem: Fatty acid oxidation R_FAOXC160 equation: [m] : (7) coa + (7) fad + (7) h2o + (7) nad + pmtcoa --> (8) accoa + (7) fadh2 + (7) h + (7) nadh R_FAOXC2031836m subsystem: Fatty acid oxidation R_FAOXC2031836m equation: [m] : coa + dlnlcgcoa + fad + h2o + nad --> accoa + fadh2 + h + lnlncgcoa + nadh R_FAOXC80 subsystem: Fatty acid oxidation R_FAOXC80 equation: [m] : (3) coa + (3) fad + (3) h2o + (3) nad + occoa --> (4) accoa + (3) fadh2 + (3) h + (3) nadh R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_FAOXC2251836m subsystem: Fatty acid oxidation R_FAOXC2251836m equation: [m] : (2) coa + dcsptn1coa + (2) h2o + (2) nad --> (2) accoa + (2) h + lnlncgcoa + (2) nadh R_FAOXC18280m subsystem: Fatty acid oxidation R_FAOXC18280m equation: [m] : (5) coa + (3) fad + (5) h2o + lneldccoa + (5) nad --> (5) accoa + (3) fadh2 + (5) h + (5) nadh + occoa R_FAOXC16180m subsystem: Fatty acid oxidation R_FAOXC16180m equation: [m] : (4) coa + (3) fad + (4) h2o + hdcoa + (4) nad --> (4) accoa + (3) fadh2 + (4) h + (4) nadh + occoa R_FAOXC2051843m subsystem: Fatty acid oxidation R_FAOXC2051843m equation: [m] : coa + h2o + nad + tmndnccoa --> accoa + h + nadh + strdnccoa R_FAOXC183803m subsystem: Fatty acid oxidation R_FAOXC183803m equation: [m] : (5) coa + (2) fad + (5) h2o + lnlncacoa + (5) nad --> (5) accoa + (2) fadh2 + (5) h + (5) nadh + occoa R_FAOXC2242046m subsystem: Fatty acid oxidation R_FAOXC2242046m equation: [m] : adrncoa + coa + fad + h2o + nad --> accoa + arachdcoa + fadh2 + h + nadh R_FAOXC200180m subsystem: Fatty acid oxidation R_FAOXC200180m equatio…
reactant: 948171
product: 948452
reactant: 948135
product: 948426
reactant: 948330
product: 948531
product: 948414
reactant: 948074
product: 948439
reactant: 948207
product: 948555
product: 948378
reactant: 948110
reactant: 948123
product: 948390
reactant: 948038
reactant: 948183
reactant: 948050
reactant: 948306
is: ENSPTRG00000005547.3
reactant: 948147
reactant: 948342
reactant: 948257
reactant: 948014
reactant: 948282
reactant: 948098
reactant: 948232

903293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Thiosulfate_O3S2
type: Species

911567
product: 005983
product: 005995
reactant: 005959
reactant: 005947
reversible: false
type: Reaction
is: ENSPTRG00000012769.4
fast: false
product: 006007
reactant: 005971
product: 006019
notes: R_GPIDAer subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDAer equation: [r] : gpi_prot_hs + h2o --> dgpi_prot_hs + h + hdca R_GPIDA2er subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_GPIDA2er equation: [r] : em2emgacpail_prot_hs + h2o --> dem2emgacpail_prot_hs + h + hdca

004765
stoichiometry: 1.0
species: 894927
type: SpeciesReference

878607
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _4-Methylzymosterol intermediate 2_C28H44O
type: Species

950979
stoichiometry: 1.0
species: 884838
type: SpeciesReference

911454
stoichiometry: 1.0
species: 887946
type: SpeciesReference

912263
stoichiometry: 1.0
species: 887983
type: SpeciesReference

890794
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: ganglioside GM1 (homo sapiens)_C55H95N3O30FULLRCO
type: Species

900316
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Prostaglandin E1_C20H33O5
type: Species

922977
stoichiometry: 1.0
species: 894395
type: SpeciesReference

907617
product: 968364
reversible: false
is: ENSPTRG00000008721.3
type: Reaction
reactant: 968352
notes: R_ALOX12R subsystem: Eicosanoid Metabolism R_ALOX12R equation: [c] : arachd + o2 --> 12RHPET
is: http://identifiers.org/ec-code/1.13.11.31
fast: false
reactant: 968340
name: Arachidonate 12-lipoxygenase R

996690
stoichiometry: 1.0
species: 877372
type: SpeciesReference

953845
stoichiometry: 1.0
species: 900280
type: SpeciesReference

941989
stoichiometry: 1.0
species: 885490
type: SpeciesReference

963127
stoichiometry: 3.0
species: 891471
type: SpeciesReference

001473
stoichiometry: 17.0
species: 891519
type: SpeciesReference

991965
stoichiometry: 1.0
species: 902800
type: SpeciesReference

910644
stoichiometry: 1.0
species: 896789
type: SpeciesReference

892777
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: heparan sulfate, precursor 6_C65H96N3O53X
type: Species

900317
product: 908085
product: 908037
product: 908061
reactant: 908013
reactant: 907989
reactant: 908001
product: 908025
product: 908049
reactant: 907977
notes: R_C3STDH1r subsystem: Cholesterol Metabolism R_C3STDH1r equation: [r] : 4mzym_int1 + nad --> 4mzym_int2 + co2 + h + nadh R_C4STMO2Pr subsystem: Cholesterol Metabolism R_C4STMO2Pr equation: [r] : 4mzym_int2 + nadp + o2 --> co2 + h + nadph + zym_int2 R_C4STMO2r subsystem: Cholesterol Metabolism R_C4STMO2r equation: [r] : 4mzym_int2 + nad + o2 --> co2 + h + nadh + zym_int2 R_C3STDH1Pr subsystem: Cholesterol Metabolism R_C3STDH1Pr equation: [r] : 4mzym_int1 + nadp --> 4mzym_int2 + co2 + h + nadph
is: ENSPTRG00000022390.3
is: http://identifiers.org/ec-code/5.3.3.1
fast: false
reactant: 907965
reversible: false
product: 908073
type: Reaction

002001
stoichiometry: 1.0
species: 901753
type: SpeciesReference

959906
stoichiometry: 1.0
species: 901549
type: SpeciesReference

913350
stoichiometry: 1.0
species: 899372
type: SpeciesReference

876801
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _13-cis-retinoate_C20H27O2
type: Species

906120
stoichiometry: 1.0
species: 891591
type: SpeciesReference

997437
stoichiometry: 4.0
species: 897492
type: SpeciesReference

979101
stoichiometry: 1.0
species: 896403
type: SpeciesReference

985601
stoichiometry: 1.0
species: 903125
type: SpeciesReference

002643
stoichiometry: 25.0
species: 898092
type: SpeciesReference

975991
stoichiometry: 1.0
species: 882805
type: SpeciesReference

899359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Phenylalanine_C9H11NO2
type: Species

909225
reactant: 983796
reversible: false
notes: R_NTPP11 subsystem: Nucleotides R_NTPP11 equation: [c] : h2o + xtp --> h + ppi + xmp R_NTPP10 subsystem: Nucleotides R_NTPP10 equation: [c] : ditp + h2o --> dimp + h + ppi R_NTPP9 subsystem: Nucleotides R_NTPP9 equation: [c] : h2o + itp --> h + imp + ppi
type: Reaction
product: 983892
product: 983844
reactant: 983832
product: 983868
product: 983880
reactant: 983808
reactant: 983820
is: ENSPTRG00000013194.2
product: 983856
is: http://identifiers.org/ec-code/3.6.1.19
fast: false

893127
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Imidazole-4-acetate_C5H5N2O2
type: Species

905018
stoichiometry: 1.0
species: 895024
type: SpeciesReference

980234
stoichiometry: 1.0
species: 884343
type: SpeciesReference

987879
stoichiometry: 1.0
species: 896897
type: SpeciesReference

896982
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: (R)-Methylmalonyl-CoA_C25H35N7O19P3S
type: Species

909537
product: 986759
reactant: 986675
reactant: 986651
reactant: 986639
reactant: 986699
type: Reaction
product: 986771
fast: false
product: 986735
notes: R_GLNtN1 subsystem: Transport, Extracellular R_GLNtN1 equation: gln-L[e] + h[c] + (2) na1[e] <==> gln-L[c] + h[e] + (2) na1[c] R_SERtN1 subsystem: Transport, Extracellular R_SERtN1 equation: h[c] + (2) na1[e] + ser-L[e] <==> h[e] + (2) na1[c] + ser-L[c] R_ASNtN1 subsystem: Transport, Extracellular R_ASNtN1 equation: asn-L[e] + h[c] + (2) na1[e] <==> asn-L[c] + h[e] + (2) na1[c] R_ALAtN1 subsystem: Transport, Extracellular R_ALAtN1 equation: ala-L[e] + h[c] + (2) na1[e] <==> ala-L[c] + h[e] + (2) na1[c]
product: 986747
product: 986711
reactant: 986663
is: ENSPTRG00000021860.5
product: 986723
reactant: 986687
reversible: true

916248
stoichiometry: 1.0
species: 878631
type: SpeciesReference

893502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 14_C166H267N11O145S8
type: Species

007217
stoichiometry: 1.0
species: 881414
type: SpeciesReference

944629
stoichiometry: 2.0
species: 895919
type: SpeciesReference

955532
stoichiometry: 1.0
species: 891483
type: SpeciesReference

976137
stoichiometry: 1.0
species: 891664
type: SpeciesReference

995154
stoichiometry: 111.0
species: 891531
type: SpeciesReference

935204
stoichiometry: 1.0
species: 882030
type: SpeciesReference

969853
stoichiometry: 8.0
species: 897528
type: SpeciesReference

878823
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8
type: Species

976632
stoichiometry: 3.0
species: 885816
type: SpeciesReference

900629
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Pyridoxamine_C8H13N2O2
type: Species

903295
reactant: 930568
is: ENSPTRG00000013588.4
type: Reaction
fast: false
notes: R_GALt1r subsystem: Transport, Extracellular R_GALt1r equation: gal[e] <==> gal[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]
product: 930604
reversible: true
reactant: 930580
product: 930592

998128
stoichiometry: 3.0
species: 884073
type: SpeciesReference

927175
stoichiometry: 2.0
species: 891411
type: SpeciesReference

940067
stoichiometry: 1.0
species: 895036
type: SpeciesReference

877782
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3-Hydroxy-2-methylpropanoate_C4H7O3
type: Species

975582
stoichiometry: 1.0
species: 901474
type: SpeciesReference

983555
stoichiometry: 2.0
species: 901330
type: SpeciesReference

980742
stoichiometry: 1.0
species: 896873
type: SpeciesReference

890228
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: D-Glucarate_C6H8O8
type: Species

903584
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
type: Species

892134
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Hydroxymethylbilane_C40H38N4O17
type: Species

898612
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Oxalate_C2O4
type: Species

938897
stoichiometry: 1.0
species: 899530
type: SpeciesReference

928312
stoichiometry: 4.0
species: 903052
type: SpeciesReference

008318
stoichiometry: 1.0
species: 898636
type: SpeciesReference

953910
stoichiometry: 1.0
species: 903970
type: SpeciesReference

923594
stoichiometry: 1.0
species: 903970
type: SpeciesReference

886057
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: dCTP_C9H12N3O13P3
type: Species

909821
stoichiometry: 1.0
species: 892945
type: SpeciesReference

892449
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 1_C79H115N5O99S11
type: Species

958741
stoichiometry: 1.0
species: 898044
type: SpeciesReference

975258
stoichiometry: 2.0
species: 891591
type: SpeciesReference

957463
stoichiometry: 1.0
species: 877432
type: SpeciesReference

937085
stoichiometry: 1.0
species: 882685
type: SpeciesReference

885392
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate precursor (GalNAc-GlcA-(Gal)2-Xyl-L-Ser (protein))_C31H49NO25X
type: Species

983615
stoichiometry: 1.0
species: 900641
type: SpeciesReference

908235
product: 975678
modifier: 975702
notes: R_GHMT2rm subsystem: Glycine, Serine, and Threonine Metabolism R_GHMT2rm equation: [m] : ser-L + thf <==> gly + h2o + mlthf R_GHMT3m subsystem: Lysine Metabolism R_GHMT3m equation: [m] : 3htmelys + h --> 4tmeabut + gly
modifier: 975750
is: http://identifiers.org/ec-code/2.1.2.1
modifier: 975714
fast: false
reactant: 975666
is: ENSPTRG00000005124.4
reversible: false
reactant: 975654
product: 975690
modifier: 975738
type: Reaction
modifier: 975726

887873
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: eicosatetranoyl coenzyme A_C41H62N7O17P3S
type: Species

912686
stoichiometry: 6.0
species: 891591
type: SpeciesReference

909227
stoichiometry: 1.0
species: 882781
type: SpeciesReference

926609
stoichiometry: 1.0
species: 884391
type: SpeciesReference

008014
stoichiometry: 1.0
species: 889346
type: SpeciesReference

974605
stoichiometry: 1.0
species: 902884
type: SpeciesReference

932585
stoichiometry: 1.0
species: 897720
type: SpeciesReference

905789
type: Reaction
product: 953071
product: 953035
reactant: 953022
is: ENSPTRG00000019635.4
reactant: 953010
reactant: 952986
reversible: true
product: 953059
notes: R_SELt4_3 subsystem: Transport, Extracellular R_SELt4_3 equation: (3) na1[e] + sel[e] <==> (3) na1[c] + sel[c] R_SO4t4_3 subsystem: Transport, Extracellular R_SO4t4_3 equation: (3) na1[e] + so4[e] <==> (3) na1[c] + so4[c] R_TSULt4_3 subsystem: Transport, Extracellular R_TSULt4_3 equation: (3) na1[e] + tsul[e] <==> (3) na1[c] + tsul[c]
reactant: 952998
fast: false
product: 953047

950930
stoichiometry: 1.0
species: 885212
type: SpeciesReference

882793
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: ATP_C10H12N5O13P3
type: Species

963518
stoichiometry: 5.0
species: 902836
type: SpeciesReference

928252
stoichiometry: 1.0
species: 881258
type: SpeciesReference

913762
stoichiometry: 2.0
species: 879643
type: SpeciesReference

908459
stoichiometry: 6.0
species: 884427
type: SpeciesReference

912529
stoichiometry: 6.0
species: 891604
type: SpeciesReference

923714
stoichiometry: 1.0
species: 888804
type: SpeciesReference

902644
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate_C27H45O5
type: Species

901269
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Se-Adenosylselenohomocysteine_C14H20N6O5Se
type: Species

006007
stoichiometry: 1.0
species: 886348
type: SpeciesReference

954155
stoichiometry: 2.0
species: 881608
type: SpeciesReference

921398
stoichiometry: 1.0
species: 887046
type: SpeciesReference

919668
stoichiometry: 1.0
species: 890155
type: SpeciesReference

990147
stoichiometry: 32.0
species: 903488
type: SpeciesReference

986338
stoichiometry: 9.0
species: 897395
type: SpeciesReference

971551
stoichiometry: 1.0
species: 891591
type: SpeciesReference

997292
stoichiometry: 1.0
species: 891591
type: SpeciesReference

888708
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Formate_CH1O2
type: Species

884427
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Coenzyme A_C21H32N7O16P3S
type: Species

965234
stoichiometry: 1.0
species: 891591
type: SpeciesReference

929964
stoichiometry: 1.0
species: 880159
type: SpeciesReference

892233
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Homovanillate_C9H9O4
type: Species

924690
stoichiometry: 1.0
species: 881957
type: SpeciesReference

913614
stoichiometry: 1.0
species: 884620
type: SpeciesReference

884572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Coproporphyrinogen III_C36H40N4O8
type: Species

955088
stoichiometry: 1.0
species: 888611
type: SpeciesReference

982121
stoichiometry: 1.0
species: 897888
type: SpeciesReference

888115
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Estrone_C18H22O2
type: Species

889358
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Glucose 6-phosphate_C6H11O9P
type: Species

890301
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Glutamate 5-phosphate_C5H8NO7P
type: Species

902643
product: 925704
fast: false
product: 925680
notes: R_GLUCYS subsystem: Glutathione Metabolism R_GLUCYS equation: [c] : atp + cys-L + glu-L --> adp + glucys + h + pi
type: Reaction
name: gamma-glutamylcysteine synthetase
reactant: 925644
product: 925692
reactant: 925668
is: http://identifiers.org/ec-code/6.3.2.2
reversible: false
product: 925716
is: ENSPTRG00000000973.3
is: ENSPTRG00000018290.3
reactant: 925656

929250
stoichiometry: 1.0
species: 881752
type: SpeciesReference

981989
stoichiometry: 1.0
species: 883747
type: SpeciesReference

897383
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

913786
stoichiometry: 4.0
species: 891483
type: SpeciesReference

916983
stoichiometry: 1.0
species: 902512
type: SpeciesReference

891604
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: H+_H
type: Species

930208
stoichiometry: 1.0
species: 891206
type: SpeciesReference

992328
stoichiometry: 1.0
species: 893235
type: SpeciesReference

879126
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-Methylthio-5-deoxy-D-ribose 1-phosphate_C6H11O7PS
type: Species

907917
stoichiometry: 3.0
species: 896451
type: SpeciesReference

953096
stoichiometry: 1.0
species: 877299
type: SpeciesReference

971299
stoichiometry: 1.0
species: 889839
type: SpeciesReference

983978
stoichiometry: 1.0
species: 884958
type: SpeciesReference

992485
stoichiometry: 4.0
species: 891604
type: SpeciesReference

924970
stoichiometry: 1.0
species: 891664
type: SpeciesReference

984508
stoichiometry: 1.0
species: 891640
type: SpeciesReference

910065
product: 992449
reactant: 992389
type: Reaction
notes: R_CAMPt subsystem: Transport, Extracellular R_CAMPt equation: atp[c] + camp[c] + h2o[c] --> adp[c] + camp[e] + h[c] + pi[c] R_CGMPt subsystem: Transport, Extracellular R_CGMPt equation: _35cgmp[c] + atp[c] + h2o[c] --> 35cgmp[e] + adp[c] + h[c] + pi[c]
product: 992413
reversible: false
reactant: 992401
fast: false
product: 992425
product: 992437
is: ENSPTRG00000015675.5
reactant: 992365
reactant: 992377
product: 992461

908456
is: ENSPTRG00000000051.4
product: 978654
reactant: 978569
is: ENSPTRG00000009296.4
product: 978630
is: ENSPTRG00000012922.4
reactant: 978556
is: ENSPTRG00000002775.5
is: http://identifiers.org/ec-code/3.1.4.11
product: 978606
product: 978642
fast: false
is: ENSPTRG00000013500.4
is: ENSPTRG00000003828.3
product: 978618
is: ENSPTRG00000015551.4
type: Reaction
reactant: 978581
is: ENSPTRG00000013242.5
is: ENSPTRG00000015207.4
is: http://identifiers.org/ec-code/3.1.4.3
is: ENSPTRG00000008395.4
notes: R_PI4PLC subsystem: Inositol Phosphate Metabolism R_PI4PLC equation: [c] : h2o + pail4p_hs --> dag_hs + h + mi14p R_PI45PLC subsystem: Inositol Phosphate Metabolism R_PI45PLC equation: [c] : h2o + pail45p_hs --> dag_hs + h + mi145p R_PIPLC subsystem: Inositol Phosphate Metabolism R_PIPLC equation: [c] : h2o + pail_hs --> dag_hs + h + mi1p-D
is: ENSPTRG00000014751.4
is: ENSPTRG00000004742.4
reactant: 978594
is: ENSPTRG00000006916.4
reversible: false
is: ENSPTRG00000012778.4

878192
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Sulfopyruvate_C3H2O6S
type: Species

892558
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 4_C73H104N4O92S10
type: Species

962403
stoichiometry: 1.0
species: 902138
type: SpeciesReference

892025
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S
type: Species

973663
stoichiometry: 1.0
species: 896946
type: SpeciesReference

883904
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Cholesterol_C27H46O
type: Species

994769
stoichiometry: 1.0
species: 897443
type: SpeciesReference

905897
product: 953949
reactant: 953910
reactant: 953883
is: http://identifiers.org/ec-code/2.7.7.12
is: http://identifiers.org/ec-code/2.7.7.10
reversible: true
product: 953936
product: 953923
reactant: 953896
fast: false
is: ENSPTRG00000020886.3
reactant: 953870
notes: R_GALT subsystem: Galactose metabolism R_GALT equation: [c] : gal1p + h + utp <==> ppi + udpgal R_UGLT subsystem: Galactose metabolism R_UGLT equation: [c] : gal1p + udpg <==> g1p + udpgal
type: Reaction

984026
stoichiometry: 1.0
species: 884886
type: SpeciesReference

915319
stoichiometry: 1.0
species: 893151
type: SpeciesReference

957571
stoichiometry: 1.0
species: 894927
type: SpeciesReference

925380
stoichiometry: 1.0
species: 884657
type: SpeciesReference

927284
stoichiometry: 1.0
species: 883482
type: SpeciesReference

949255
stoichiometry: 1.0
species: 900436
type: SpeciesReference

964071
stoichiometry: 1.0
species: 884427
type: SpeciesReference

900028
is: ENSPTRG00000018128.2
fast: false
type: Reaction
reversible: false
name: lactoylglutathione lyase
is: http://identifiers.org/ec-code/4.4.1.5
notes: R_LGTHL subsystem: Pyruvate Metabolism R_LGTHL equation: [c] : gthrd + mthgxl --> lgt-S
reactant: 906834
product: 906846
reactant: 906822

935313
stoichiometry: 1.0
species: 898816
type: SpeciesReference

944111
stoichiometry: 1.0
species: 896511
type: SpeciesReference

891820
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Hexadecanoate (n-C16:0)_C16H31O2
type: Species

001725
stoichiometry: 1.0
species: 893526
type: SpeciesReference

903186
reactant: 929747
type: Reaction
reversible: true
notes: R_KCCt subsystem: Transport, Extracellular R_KCCt equation: cl[e] + k[e] <==> cl[c] + k[c]
reactant: 929759
fast: false
product: 929784
product: 929772
name: K+-Cl- cotransport
is: ENSPTRG00000013578.4

913097
stoichiometry: 1.0
species: 882781
type: SpeciesReference

973735
stoichiometry: 1.0
species: 897067
type: SpeciesReference

925224
stoichiometry: 4.0
species: 891483
type: SpeciesReference

924582
stoichiometry: 1.0
species: 880195
type: SpeciesReference

889070
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Type IIIH glycolipid_C70H122N3O40FULLRCO
type: Species

966963
stoichiometry: 1.0
species: 879029
type: SpeciesReference

886660
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _7,8-Dihydrofolate_C19H19N7O6
type: Species

888816
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: D-Fructose_C6H12O6
type: Species

975690
stoichiometry: 1.0
species: 890542
type: SpeciesReference

887764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Erythrose 4-phosphate_C4H7O7P
type: Species

909336
stoichiometry: 1.0
species: 902198
type: SpeciesReference

877890
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Methoxy-4-hydroxyphenylglycolaldehyde_C9H10O4
type: Species

929674
stoichiometry: 1.0
species: 904248
type: SpeciesReference

955749
stoichiometry: 1.0
species: 890686
type: SpeciesReference

917950
stoichiometry: 1.0
species: 896403
type: SpeciesReference

936868
stoichiometry: 1.0
species: 892110
type: SpeciesReference

940391
stoichiometry: 10.0
species: 881282
type: SpeciesReference

888406
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2
type: Species

900739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Pyruvate_C3H3O3
type: Species

906126
is: ENSPTRG00000019657.4
type: Reaction
reactant: 955484
name: sodium proton antiporter (H:NA is 1:1)
reversible: true
product: 955508
is: ENSPTRG00000012304.3
notes: R_NAt3_1 subsystem: Transport, Extracellular R_NAt3_1 equation: h[e] + na1[c] <==> h[c] + na1[e]
reactant: 955472
product: 955496
fast: false

902031
product: 920587
product: 920563
modifier: 920709
fast: false
modifier: 920659
modifier: 920722
reactant: 920526
reactant: 920514
modifier: 920647
notes: R_LDH_L subsystem: Glycolysis/Gluconeogenesis R_LDH_L equation: [c] : lac-L + nad <==> h + nadh + pyr R_MCLOR subsystem: Cysteine Metabolism R_MCLOR equation: [c] : mercplac + nad <==> h + mercppyr + nadh R_HPYRR2x subsystem: Glyoxylate and Dicarboxylate Metabolism R_HPYRR2x equation: [c] : h + hpyr + nadh --> glyc-S + nad R_2HBO subsystem: Propanoate Metabolism R_2HBO equation: [c] : 2hb + nad <==> 2obut + h + nadh R_LDH_Lm subsystem: Pyruvate Metabolism R_LDH_Lm equation: [m] : lac-L + nad <==> h + nadh + pyr R_GLXO1 subsystem: Glyoxylate and Dicarboxylate Metabolism R_GLXO1 equation: [c] : glx + h2o + nad --> (2) h + nadh + oxa R_CREATt4_LPAREN_2_RPAREN_r subsystem: Transport, Extracellular R_CREATt4_LPAREN_2_RPAREN_r equation: creat[e] + (2) na1[e] <==> creat[c] + (2) na1[c]
is: ENSPTRG00000003421.3
modifier: 920635
modifier: 920819
product: 920575
reactant: 920538
modifier: 920807
modifier: 920795
modifier: 920623
modifier: 920783
modifier: 920746
modifier: 920734
modifier: 920684
is: http://identifiers.org/ec-code/1.1.1.27
modifier: 920771
modifier: 920672
reactant: 920551
modifier: 920696
product: 920599
reversible: false
type: Reaction
product: 920611
modifier: 920831
modifier: 920759
reactant: 920502
reactant: 920490
is: http://identifiers.org/ec-code/1.2.3.5

998236
stoichiometry: 1.0
species: 891640
type: SpeciesReference

963626
stoichiometry: 5.0
species: 890264
type: SpeciesReference

930943
stoichiometry: 1.0
species: 899650
type: SpeciesReference

930640
stoichiometry: 1.0
species: 883675
type: SpeciesReference

932475
stoichiometry: 1.0
species: 876644
type: SpeciesReference

906535
notes: R_CK subsystem: Urea cycle/amino group metabolism R_CK equation: [m] : atp + creat <==> adp + pcreat
reversible: true
fast: false
name: ATP Creatine kinase
type: Reaction
reactant: 960038
reactant: 960050
is: http://identifiers.org/ec-code/2.7.3.2
is: ENSPTRG00000024170.3
product: 960075
product: 960062

944315
stoichiometry: 3.0
species: 899021
type: SpeciesReference

903586
fast: false
product: 933334
type: Reaction
product: 933298
reactant: 933261
reversible: false
is: http://identifiers.org/ec-code/4.1.1.15
reactant: 933274
reactant: 933249
product: 933322
is: ENSPTRG00000002372.5
reactant: 933286
notes: R_3SALACBOXL subsystem: Taurine and hypotaurine metabolism R_3SALACBOXL equation: [c] : 3sala + h --> co2 + hyptaur R_GLUDC subsystem: Glutamate metabolism R_GLUDC equation: [c] : glu-L + h --> 4abut + co2 R_LCYSTCBOXL subsystem: Taurine and hypotaurine metabolism R_LCYSTCBOXL equation: [c] : Lcyst + h --> co2 + taur
product: 933310

925500
stoichiometry: 2.0
species: 901585
type: SpeciesReference

981832
stoichiometry: 1.0
species: 903824
type: SpeciesReference

921241
stoichiometry: 1.0
species: 881101
type: SpeciesReference

887181
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Dolichyl beta-D-glucosyl phosphate, human liver homolog_C1140H1868O90P10
type: Species

956160
stoichiometry: 1.0
species: 892110
type: SpeciesReference

980475
stoichiometry: 1.0
species: 898176
type: SpeciesReference

950822
stoichiometry: 1.0
species: 883675
type: SpeciesReference

939534
stoichiometry: 1.0
species: 890167
type: SpeciesReference

934257
stoichiometry: 1.0
species: 895036
type: SpeciesReference

978458
stoichiometry: 1.0
species: 901946
type: SpeciesReference

928542
stoichiometry: 1.0
species: 889058
type: SpeciesReference

975798
stoichiometry: 1.0
species: 898901
type: SpeciesReference

939320
stoichiometry: 6.0
species: 891591
type: SpeciesReference

894903
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: de-Fuc, reducing GlcNAc removed, de-Sia form of PA6 (w/o peptide linkage)_C54H91N3O41
type: Species

988289
stoichiometry: 1.0
species: 893090
type: SpeciesReference

975148
stoichiometry: 1.0
species: 900352
type: SpeciesReference

902030
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Succinyl-CoA_C25H35N7O19P3S
type: Species

982277
stoichiometry: 1.0
species: 891555
type: SpeciesReference

983204
stoichiometry: 1.0
species: 883518
type: SpeciesReference

900026
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Pregnenolone_C21H32O2
type: Species

990589
stoichiometry: 2.0
species: 895822
type: SpeciesReference

989666
stoichiometry: 1.0
species: 880837
type: SpeciesReference

928468
stoichiometry: 1.0
species: 889094
type: SpeciesReference

942812
stoichiometry: 23.0
species: 891471
type: SpeciesReference

923484
stoichiometry: 1.0
species: 883338
type: SpeciesReference

952104
stoichiometry: 1.0
species: 897019
type: SpeciesReference

971443
stoichiometry: 1.0
species: 890228
type: SpeciesReference

935035
stoichiometry: 1.0
species: 895000
type: SpeciesReference

990039
stoichiometry: 1.0
species: 889430
type: SpeciesReference

884121
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: clupanodonyl CoA_C43H64N7O17P3S
type: Species

897492
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3
type: Species

879017
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-Hydroxyindoleacetaldehyde_C10H9NO2
type: Species

889790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N1-(5-Phospho-D-ribosyl)glycinamide_C7H14N2O8P
type: Species

885140
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), degradation product 4_C31H47NO35S3
type: Species

997184
stoichiometry: 3.0
species: 891591
type: SpeciesReference

892341
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 11_C55H81N3O67S7
type: Species

947399
stoichiometry: 1.0
species: 894261
type: SpeciesReference

995501
stoichiometry: 1.0
species: 901826
type: SpeciesReference

947206
stoichiometry: 1.0
species: 892994
type: SpeciesReference

877215
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _2-Decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone_C58H88O3
type: Species

996461
stoichiometry: 1.0
species: 880462
type: SpeciesReference

940175
stoichiometry: 6.0
species: 891640
type: SpeciesReference

956739
stoichiometry: 1.0
species: 897996
type: SpeciesReference

977214
stoichiometry: 1.0
species: 881065
type: SpeciesReference

986046
stoichiometry: 1.0
species: 882805
type: SpeciesReference

904550
name: ecgonine methyl esterase (ER)
type: Reaction
is: ENSPTRG00000015540.3
reactant: 941179
product: 941191
fast: false
reversible: false
reactant: 941167
notes: R_EGMESTr subsystem: Alkaloid biosynthesis II R_EGMESTr equation: [r] : egme + h2o --> ecgon + h + meoh
product: 941203
product: 941216

876524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: _10-formyltetrahydrofolate-[Glu](5)_C40H45N11O19
type: Species

923606
stoichiometry: 1.0
species: 899530
type: SpeciesReference

901113
reversible: false
reactant: 914112
product: 914149
is: ENSPTRG00000020038.5
reactant: 914125
product: 914185
is: http://identifiers.org/ec-code/3.1.1.3
product: 914173
product: 914161
fast: false
type: Reaction
reactant: 914137
notes: R_LPS2 subsystem: Triacylglycerol Synthesis R_LPS2 equation: [c] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS subsystem: Triacylglycerol Synthesis R_LPS equation: [c] : h2o + tag_hs --> Rtotal3 + dag_hs + h
product: 914197

924861
stoichiometry: 1.0
species: 894963
type: SpeciesReference

954047
stoichiometry: 1.0
species: 896982
type: SpeciesReference

918748
stoichiometry: 1.0
species: 881764
type: SpeciesReference

930316
stoichiometry: 1.0
species: 898200
type: SpeciesReference

909333
product: 984724
product: 984700
is: http://identifiers.org/ec-code/2.1.2.5
type: Reaction
notes: R_GluForTx subsystem: Histidine Metabolism R_GluForTx equation: [c] : forglu + h + thf --> 5forthf + glu-L R_FTCD subsystem: Folate Metabolism R_FTCD equation: [c] : 5forthf + (2) h --> methf + nh4
reactant: 984652
product: 984736
product: 984712
reactant: 984676
reactant: 984664
is: http://identifiers.org/ec-code/4.3.1.4
reversible: false
is: ENSPTRG00000014015.4
reactant: 984688
fast: false

010589
stoichiometry: 1.0
species: 899359
type: SpeciesReference

984929
stoichiometry: 2.0
species: 891483
type: SpeciesReference

004995
stoichiometry: 1.0
species: 901741
type: SpeciesReference

879991
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: R total 3 carnitine_CO2FULLR3C7H14NO2
type: Species

002751
stoichiometry: 1.0
species: 892037
type: SpeciesReference

890458
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Glutaryl-CoA_C26H37N7O19P3S
type: Species

893852
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 3_C233H371N16O205S12
type: Species

962271
stoichiometry: 3.0
species: 891640
type: SpeciesReference

915199
stoichiometry: 1.0
species: 899238
type: SpeciesReference

997849
stoichiometry: 1.0
species: 901426
type: SpeciesReference

876959
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: _1 acyl phosphoglycerol_C6H13O7PFULLRCO2
type: Species

937943
stoichiometry: 1.0
species: 900897
type: SpeciesReference

941662
stoichiometry: 1.0
species: 893042
type: SpeciesReference

947605
stoichiometry: 1.0
species: 889526
type: SpeciesReference

894080
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 17_C157H252N11O127S5X
type: Species

936700
stoichiometry: 1.0
species: 879955
type: SpeciesReference

910752
stoichiometry: 1.0
species: 898600
type: SpeciesReference

982494
stoichiometry: 1.0
species: 902920
type: SpeciesReference

908162
modifier: 975366
modifier: 975342
product: 975233
modifier: 975306
type: Reaction
fast: false
modifier: 975378
modifier: 975270
reactant: 975196
is: ENSPTRG00000013871.4
modifier: 975354
product: 975220
reactant: 975208
is: http://identifiers.org/ec-code/2.1.2.2
modifier: 975294
modifier: 975318
notes: R_GARFT subsystem: IMP Biosynthesis R_GARFT equation: [c] : 10fthf + gar <==> fgam + h + thf R_PRAGSr subsystem: IMP Biosynthesis R_PRAGSr equation: [c] : atp + gly + pram <==> adp + gar + h + pi R_PRAIS subsystem: IMP Biosynthesis R_PRAIS equation: [c] : atp + fpram --> adp + air + (2) h + pi
is: http://identifiers.org/ec-code/6.3.4.13
modifier: 975330
is: http://identifiers.org/ec-code/6.3.3.1
modifier: 975282
product: 975258
product: 975246
reversible: false

904669
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: zymosterol_C27H44O
type: Species

947062
stoichiometry: 1.0
species: 876837
type: SpeciesReference

880293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Arabinitol_C5H12O5
type: Species

986903
stoichiometry: 1.0
species: 888768
type: SpeciesReference

977080
stoichiometry: 1.0
species: 884391
type: SpeciesReference

960787
stoichiometry: 1.0
species: 891616
type: SpeciesReference

895036
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Lactaldehyde_C3H6O2
type: Species

007615
stoichiometry: 1.0
species: 884620
type: SpeciesReference

955364
stoichiometry: 1.0
species: 903560
type: SpeciesReference

901525
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Sulfite_O3S
type: Species

004485
stoichiometry: 1.0
species: 897636
type: SpeciesReference

004052
stoichiometry: 2.0
species: 893634
type: SpeciesReference

976528
stoichiometry: 2.0
species: 897395
type: SpeciesReference

906532
stoichiometry: 1.0
species: 903982
type: SpeciesReference

959568
stoichiometry: 1.0
species: 891591
type: SpeciesReference

006115
stoichiometry: 1.0
species: 881198
type: SpeciesReference

920502
stoichiometry: 1.0
species: 892305
type: SpeciesReference

990855
stoichiometry: 1.0
species: 878799
type: SpeciesReference

980342
stoichiometry: 1.0
species: 897443
type: SpeciesReference

949108
stoichiometry: 15.0
species: 898997
type: SpeciesReference

968484
stoichiometry: 4.0
species: 881258
type: SpeciesReference

883046
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Bilirubin_C33H34N4O6
type: Species

972070
stoichiometry: 1.0
species: 894212
type: SpeciesReference

916839
stoichiometry: 1.0
species: 882445
type: SpeciesReference

000918
stoichiometry: 1.0
species: 900400
type: SpeciesReference

883191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Biotin_C10H15N2O3S
type: Species

939247
stoichiometry: 1.0
species: 881330
type: SpeciesReference

946654
stoichiometry: 1.0
species: 897407
type: SpeciesReference

903730
product: 934469
reactant: 934445
name: Tetrahydrobiopterin-4a-carbinolamine dehydratase
is: ENSPTRG00000002599.3
notes: R_THBPT4ACAMDASE subsystem: Tetrahydrobiopterin R_THBPT4ACAMDASE equation: [c] : thbpt4acam --> dhbpt + h2o
fast: false
product: 934457
type: Reaction
is: http://identifiers.org/ec-code/4.2.1.96
reversible: false

905782
stoichiometry: 1.0
species: 891591
type: SpeciesReference

984592
stoichiometry: 2.0
species: 891591
type: SpeciesReference

933117
stoichiometry: 1.0
species: 898080
type: SpeciesReference

961703
stoichiometry: 3.0
species: 881632
type: SpeciesReference

970770
stoichiometry: 1.0
species: 897516
type: SpeciesReference

956316
stoichiometry: 1.0
species: 895568
type: SpeciesReference

905396
stoichiometry: 1.0
species: 892619
type: SpeciesReference

009863
stoichiometry: 1.0
species: 880933
type: SpeciesReference

951947
stoichiometry: 1.0
species: 889334
type: SpeciesReference

942692
stoichiometry: 1.0
species: 901934
type: SpeciesReference

916139
stoichiometry: 1.0
species: 903378
type: SpeciesReference

999344
stoichiometry: 1.0
species: 894927
type: SpeciesReference

884343
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: CO2_CO2
type: Species

906338
stoichiometry: 1.0
species: 891483
type: SpeciesReference

001365
stoichiometry: 3.0
species: 891483
type: SpeciesReference

898768
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phosphatidylinositol-3,4-bisphosphate (Homo sapiens)_C9H14O15P3FULLRCO2FULLR2CO2
type: Species

967098
stoichiometry: 1.0
species: 877008
type: SpeciesReference

943583
stoichiometry: 1.0
species: 888212
type: SpeciesReference

903185
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Tryptamine_C10H13N2
type: Species

911459
product: 005068
product: 005044
notes: R_SGPL12r subsystem: Sphingolipid Metabolism R_SGPL12r equation: [r] : h2o + sphs1p --> ethamp + h + hdca R_SGPL11r subsystem: Sphingolipid Metabolism R_SGPL11r equation: [r] : sph1p --> ethamp + hxdcal
reactant: 004995
reactant: 005007
product: 005056
product: 005032
is: ENSPTRG00000002598.3
is: http://identifiers.org/ec-code/4.1.2.27
type: Reaction
fast: false
reactant: 005019
reversible: false

989798
stoichiometry: 1.0
species: 889802
type: SpeciesReference

997328
stoichiometry: 1.0
species: 900026
type: SpeciesReference

003704
stoichiometry: 1.0
species: 893816
type: SpeciesReference

900208
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Proline_C5H9NO2
type: Species

005634
stoichiometry: 1.0
species: 891002
type: SpeciesReference

007954
stoichiometry: 1.0
species: 890542
type: SpeciesReference

896415
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: D-Mannose_C6H12O6
type: Species

888551
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Fe3+_Fe
type: Species

886492
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4
type: Species

902499
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S
type: Species

879342
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _6-Phospho-D-gluconate_C6H10O10P
type: Species

885719
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: dADP_C10H12N5O9P2
type: Species

937653
stoichiometry: 1.0
species: 897371
type: SpeciesReference

916670
stoichiometry: 1.0
species: 898466
type: SpeciesReference

955640
stoichiometry: 1.0
species: 878847
type: SpeciesReference

961342
stoichiometry: 1.0
species: 885937
type: SpeciesReference

900424
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Prostaglandin I2_C20H31O5
type: Species

900957
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Retinoate_C20H27O2
type: Species

006577
stoichiometry: 1.0
species: 882224
type: SpeciesReference

972928
stoichiometry: 1.0
species: 894554
type: SpeciesReference

884886
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate A (GalNAc4S-GlcA), degradation product 4_C31H49NO29S
type: Species

905921
product: 954059
reactant: 954047
notes: R_MMEm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMEm equation: [m] : mmcoa-R <==> mmcoa-S
is: ENSPTRG00000012044.3
is: http://identifiers.org/ec-code/5.1.99.1
fast: false
reversible: true
name: methylmalonyl-CoA epimerase/racemase
type: Reaction

966745
stoichiometry: 1.0
species: 895000
type: SpeciesReference

954263
stoichiometry: 1.0
species: 895363
type: SpeciesReference

005706
stoichiometry: 2.0
species: 896958
type: SpeciesReference

973880
stoichiometry: 1.0
species: 884766
type: SpeciesReference

964874
stoichiometry: 1.0
species: 903185
type: SpeciesReference

951791
stoichiometry: 1.0
species: 897467
type: SpeciesReference

915465
stoichiometry: 1.0
species: 893127
type: SpeciesReference

986265
stoichiometry: 1.0
species: 877926
type: SpeciesReference

936170
stoichiometry: 1.0
species: 877650
type: SpeciesReference

922347
stoichiometry: 1.0
species: 881897
type: SpeciesReference

897768
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C42H70N3O30X
type: Species

935745
stoichiometry: 1.0
species: 891977
type: SpeciesReference

954375
stoichiometry: 1.0
species: 901041
type: SpeciesReference

005333
stoichiometry: 1.0
species: 876789
type: SpeciesReference

976741
stoichiometry: 3.0
species: 886045
type: SpeciesReference

888273
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Ethanol_C2H6O
type: Species

927998
stoichiometry: 1.0
species: 880559
type: SpeciesReference

963963
stoichiometry: 1.0
species: 881620
type: SpeciesReference

899895
notes: R_BAAT1x subsystem: Bile Acid Biosynthesis R_BAAT1x equation: [x] : cholcoa + gly --> coa + gchola R_BAAT4x subsystem: Bile Acid Biosynthesis R_BAAT4x equation: [x] : dcholcoa + gly --> coa + gdchola R_BAAT2x subsystem: Bile Acid Biosynthesis R_BAAT2x equation: [x] : cholcoa + taur --> coa + tchola R_BAAT3x subsystem: Bile Acid Biosynthesis R_BAAT3x equation: [x] : dgcholcoa + gly --> coa + dgchol R_BAAT5x subsystem: Bile Acid Biosynthesis R_BAAT5x equation: [x] : dcholcoa + taur --> coa + tdchola
product: 905914
reactant: 905806
reactant: 905818
product: 905902
is: ENSPTRG00000021198.4
fast: false
is: http://identifiers.org/ec-code/2.3.1.65
reactant: 905842
reversible: false
product: 905890
product: 905866
product: 905854
type: Reaction
reactant: 905794
product: 905878
reactant: 905830

980126
stoichiometry: 1.0
species: 879943
type: SpeciesReference

929516
stoichiometry: 5.0
species: 891483
type: SpeciesReference

943789
stoichiometry: 1.0
species: 896390
type: SpeciesReference

998814
stoichiometry: 1.0
species: 894383
type: SpeciesReference

933613
stoichiometry: 1.0
species: 889226
type: SpeciesReference

900955
product: 912686
product: 912674
type: Reaction
reactant: 912541
is: ENSPTRG00000003786.3
reactant: 912517
product: 912613
reactant: 912565
reversible: true
reactant: 912553
reactant: 912505
reactant: 912493
reactant: 912589
notes: R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_ACACt2 subsystem: Transport, Extracellular R_ACACt2 equation: acac[e] + h[e] <==> acac[c] + h[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_PYRt2p subsystem: D-alanine metabolism R_PYRt2p equation: h[c] + pyr[c] <==> h[x] + pyr[x] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c]
product: 912662
product: 912699
fast: false
product: 912638
product: 912650
product: 912601
product: 912626
reactant: 912577
reactant: 912529

958525
stoichiometry: 1.0
species: 899578
type: SpeciesReference

968799
stoichiometry: 1.0
species: 903909
type: SpeciesReference

007362
stoichiometry: 2.0
species: 904428
type: SpeciesReference

986999
stoichiometry: 1.0
species: 897249
type: SpeciesReference

882347
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: (+)-alpha-Pinene_C10H16
type: Species

882066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: S-Adenosyl-L-methionine_C15H23N6O5S
type: Species

899783
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Propanoyl-CoA_C24H36N7O17P3S
type: Species

981601
stoichiometry: 1.0
species: 896378
type: SpeciesReference

994986
stoichiometry: 1.0
species: 887425
type: SpeciesReference

909602
stoichiometry: 1.0
species: 886612
type: SpeciesReference

925935
stoichiometry: 1.0
species: 879222
type: SpeciesReference

904970
stoichiometry: 12.0
species: 897321
type: SpeciesReference

964400
stoichiometry: 1.0
species: 898925
type: SpeciesReference

963396
stoichiometry: 1.0
species: 889358
type: SpeciesReference

910762
product: 996654
reactant: 996642
notes: R_ACGAM2E subsystem: Aminosugar Metabolism R_ACGAM2E equation: [c] : acgam <==> acmana
is: ENSPTRG00000022420.3
is: http://identifiers.org/ec-code/5.1.3.8
fast: false
reversible: true
name: N-acetylglucosamine 2-epimerase
type: Reaction

934926
stoichiometry: 1.0
species: 893151
type: SpeciesReference

989509
stoichiometry: 1.0
species: 903728
type: SpeciesReference

996242
stoichiometry: 1.0
species: 888418
type: SpeciesReference

917622
stoichiometry: 1.0
species: 891591
type: SpeciesReference

877432
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3,4-Dihydroxymandelaldehyde_C8H8O4
type: Species

914669
stoichiometry: 1.0
species: 880957
type: SpeciesReference

996315
stoichiometry: 1.0
species: 900316
type: SpeciesReference

969003
stoichiometry: 1.0
species: 884415
type: SpeciesReference

949677
stoichiometry: 1.0
species: 891892
type: SpeciesReference

912118
stoichiometry: 1.0
species: 903824
type: SpeciesReference

009525
stoichiometry: 1.0
species: 901717
type: SpeciesReference

952321
stoichiometry: 1.0
species: 891892
type: SpeciesReference

903417
reactant: 932030
reactant: 932066
notes: R_CLOXAtex2 subsystem: Transport, Extracellular R_CLOXAtex2 equation: (2) cl[e] + oxa[c] --> (2) cl[c] + oxa[e] R_SO4CLtex2 subsystem: Transport, Extracellular R_SO4CLtex2 equation: cl[c] + (2) so4[e] --> cl[e] + (2) so4[c] R_SO4OXAtex2 subsystem: Transport, Extracellular R_SO4OXAtex2 equation: oxa[c] + (2) so4[e] --> oxa[e] + (2) so4[c] R_CLFORtex2 subsystem: Transport, Extracellular R_CLFORtex2 equation: (2) cl[e] + for[c] --> (2) cl[c] + for[e] R_CLOHtex2 subsystem: Transport, Extracellular R_CLOHtex2 equation: (2) cl[e] + oh1[c] --> (2) cl[c] + oh1[e] R_CLHCO3tex2 subsystem: Transport, Extracellular R_CLHCO3tex2 equation: (2) cl[e] + hco3[c] --> (2) cl[c] + hco3[e]
product: 932138
product: 932126
product: 932102
reactant: 932042
reactant: 932018
type: Reaction
product: 932174
product: 932162
fast: false
reactant: 932078
is: ENSPTRG00000018320.3
product: 932114
reversible: false
is: ENSPTRG00000014895.5
is: ENSPTRG00000001194.4
product: 932150
reactant: 932054
reactant: 932090

992765
stoichiometry: 1.0
species: 882781
type: SpeciesReference

908672
reactant: 980065
notes: R_LPSe subsystem: Triacylglycerol Synthesis R_LPSe equation: [e] : h2o + tag_hs --> Rtotal3 + dag_hs + h R_LPS2e subsystem: Fatty Acid Metabolism R_LPS2e equation: [e] : dag_hs + h2o --> Rtotal + h + mag_hs R_LPS3e subsystem: Fatty Acid Metabolism R_LPS3e equation: [e] : h2o + mag_hs --> Rtotal2 + glyc + h
product: 980186
is: ENSPTRG00000007115.2
product: 980114
product: 980174
fast: false
product: 980162
reactant: 980077
is: http://identifiers.org/ec-code/3.1.1.23
product: 980150
reactant: 980102
type: Reaction
is: http://identifiers.org/ec-code/3.1.1.3
product: 980138
reactant: 980089
product: 980126
reversible: false

008887
stoichiometry: 1.0
species: 889678
type: SpeciesReference

989232
stoichiometry: 1.0
species: 897443
type: SpeciesReference

959496
stoichiometry: 2.0
species: 899578
type: SpeciesReference

944533
stoichiometry: 1.0
species: 895931
type: SpeciesReference

894505
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate II (core 2-linked), degradation product 7_C44H73N4O30X
type: Species

932693
stoichiometry: 1.0
species: 883567
type: SpeciesReference

933953
stoichiometry: 1.0
species: 880595
type: SpeciesReference

879234
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

000494
stoichiometry: 1.0
species: 879246
type: SpeciesReference

882961
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Bilirubin beta-diglucuronide_C45H50N4O18
type: Species

966527
stoichiometry: 1.0
species: 899530
type: SpeciesReference

890674
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Glycerol_C3H8O3
type: Species

921107
stoichiometry: 1.0
species: 897261
type: SpeciesReference

987639
stoichiometry: 1.0
species: 882005
type: SpeciesReference

949953
stoichiometry: 1.0
species: 895605
type: SpeciesReference

899470
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _2-Hydroxyphytanoyl-CoA_C41H70N7O18P3S
type: Species

887033
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _4,8 dimethylnonanoyl-CoA_C32H54N7O17P3S
type: Species

904213
reactant: 937883
notes: R_RDH3 subsystem: Vitamin A Metabolism R_RDH3 equation: [c] : nad + retinol-cis-11 <==> h + nadh + retinal-11-cis R_RDH2 subsystem: Vitamin A Metabolism R_RDH2 equation: [c] : nad + retinol-9-cis <==> h + nadh + retinal-cis-9 R_RDH1 subsystem: Vitamin A Metabolism R_RDH1 equation: [c] : nad + retinol <==> h + nadh + retinal R_RDH4 subsystem: Vitamin A Metabolism R_RDH4 equation: [c] : nad + retinol-cis-13 <==> h + nadh + retinal-cis-13
product: 937979
reactant: 937859
product: 937943
product: 937955
is: ENSPTRG00000005061.2
type: Reaction
reactant: 937907
reversible: true
product: 937919
product: 937967
fast: false
reactant: 937895
product: 937931
is: http://identifiers.org/ec-code/1.1.1.105
reactant: 937871

882637
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N(omega)-(L-Arginino)succinate_C10H17N4O6
type: Species

911162
stoichiometry: 1.0
species: 894759
type: SpeciesReference

008171
stoichiometry: 1.0
species: 882298
type: SpeciesReference

906750
stoichiometry: 1.0
species: 900897
type: SpeciesReference

956016
stoichiometry: 1.0
species: 879102
type: SpeciesReference

933334
stoichiometry: 3.0
species: 884319
type: SpeciesReference

881668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: _2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate_C9H12N5O13P3
type: Species

939847
stoichiometry: 1.0
species: 883687
type: SpeciesReference

950677
stoichiometry: 9.0
species: 887582
type: SpeciesReference

972674
stoichiometry: 1.0
species: 888297
type: SpeciesReference

935481
stoichiometry: 3.0
species: 897900
type: SpeciesReference

001593
stoichiometry: 1.0
species: 893912
type: SpeciesReference

887449
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: dTDP_C10H13N2O11P2
type: Species

952756
stoichiometry: 1.0
species: 888370
type: SpeciesReference

978037
stoichiometry: 1.0
species: 895290
type: SpeciesReference

880075
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: R total Coenzyme A_CO2FULLRC21H31N7O15P3S
type: Species

007096
stoichiometry: 1.0
species: 895266
type: SpeciesReference

005056
stoichiometry: 1.0
species: 892897
type: SpeciesReference

902799
reactant: 927356
is: ENSPTRG00000002619.4
type: Reaction
notes: R_PROAKGOX1r subsystem: Arginine and Proline Metabolism R_PROAKGOX1r equation: [r] : akg + o2 + pro-L --> 4hpro-LT + co2 + succ
product: 927416
product: 927404
name: L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) (ER)
reactant: 927380
fast: false
is: ENSPTRG00000009772.3
is: ENSPTRG00000017213.5
reversible: false
product: 927392
is: http://identifiers.org/ec-code/1.14.11.2
reactant: 927368

941444
stoichiometry: 1.0
species: 887302
type: SpeciesReference

918073
stoichiometry: 1.0
species: 895895
type: SpeciesReference

892994
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Indole-3-acetaldehyde_C10H9NO
type: Species

910209
stoichiometry: 1.0
species: 898864
type: SpeciesReference

906751
modifier: 961426
is: ENSPTRG00000011681.5
reversible: false
product: 961366
fast: false
modifier: 961438
product: 961390
is: http://identifiers.org/ec-code/1.1.1.105
modifier: 961450
modifier: 961462
reactant: 961306
modifier: 961474
is: http://identifiers.org/ec-code/3.1.3.5
type: Reaction
product: 961354
modifier: 961486
reactant: 961330
modifier: 961402
product: 961378
modifier: 961498
reactant: 961342
modifier: 961414
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal R_NTD11 subsystem: Purine Catabolism R_NTD11 equation: [c] : h2o + imp --> ins + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD7 subsystem: Nucleotides R_NTD7 equation: [c] : amp + h2o --> adn + pi
reactant: 961318

979968
stoichiometry: 1.0
species: 889815
type: SpeciesReference

004329
stoichiometry: 1.0
species: 884995
type: SpeciesReference

895190
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Leukotriene B4_C20H31O4
type: Species

895749
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Lysine_C6H15N2O2
type: Species

001027
stoichiometry: 1.0
species: 897395
type: SpeciesReference

923049
stoichiometry: 1.0
species: 894248
type: SpeciesReference

945085
stoichiometry: 1.0
species: 891591
type: SpeciesReference

972288
stoichiometry: 1.0
species: 894615
type: SpeciesReference

922230
stoichiometry: 1.0
species: 899795
type: SpeciesReference

931715
stoichiometry: 1.0
species: 899263
type: SpeciesReference

950121
stoichiometry: 1.0
species: 895568
type: SpeciesReference

962838
stoichiometry: 1.0
species: 894915
type: SpeciesReference

958827
stoichiometry: 1.0
species: 903209
type: SpeciesReference

914366
stoichiometry: 2.0
species: 891591
type: SpeciesReference

928986
stoichiometry: 1.0
species: 890155
type: SpeciesReference

943366
stoichiometry: 3.0
species: 881644
type: SpeciesReference

903415
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Tyrosine_C9H11NO3
type: Species

985185
stoichiometry: 1.0
species: 889678
type: SpeciesReference

960968
stoichiometry: 1.0
species: 899021
type: SpeciesReference

962114
stoichiometry: 1.0
species: 891591
type: SpeciesReference

946870
stoichiometry: 2.0
species: 891519
type: SpeciesReference

979257
stoichiometry: 2.0
species: 885707
type: SpeciesReference

941336
stoichiometry: 6.0
species: 897261
type: SpeciesReference

878048
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _3-Oxododecanoyl-CoA_C33H52N7O18P3S
type: Species

961885
stoichiometry: 1.0
species: 884073
type: SpeciesReference

955412
stoichiometry: 1.0
species: 903488
type: SpeciesReference

880800
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: nLc5Cer_C52H92N3O27FULLRCO
type: Species

901117
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: de-Fuc form of PA6_C84H135N6O61X
type: Species

898358
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: octadecadienoate (n-C18:2)_C18H31O2
type: Species

922601
stoichiometry: 1.0
species: 898563
type: SpeciesReference

896269
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Malonyl-CoA_C24H33N7O19P3S
type: Species

898297
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: octadecanoate (n-C18:0)_C18H35O2
type: Species

987302
stoichiometry: 1.0
species: 899530
type: SpeciesReference

954689
stoichiometry: 1.0
species: 899494
type: SpeciesReference

996048
stoichiometry: 1.0
species: 891591
type: SpeciesReference

891182
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GT2 (homo sapiens)_C71H117N5O41FULLRCO
type: Species

970214
stoichiometry: 1.0
species: 881258
type: SpeciesReference

946592
stoichiometry: 1.0
species: 884427
type: SpeciesReference

972130
stoichiometry: 1.0
species: 895086
type: SpeciesReference

961186
stoichiometry: 1.0
species: 897552
type: SpeciesReference

917249
stoichiometry: 4.0
species: 884319
type: SpeciesReference

928878
stoichiometry: 1.0
species: 891351
type: SpeciesReference

913906
stoichiometry: 1.0
species: 900909
type: SpeciesReference

885502
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: CTP_C9H12N3O14P3
type: Species

991521
stoichiometry: 16.0
species: 884391
type: SpeciesReference

959083
stoichiometry: 1.0
species: 893151
type: SpeciesReference

004113
stoichiometry: 2.0
species: 893502
type: SpeciesReference

940816
stoichiometry: 1.0
species: 897443
type: SpeciesReference

005851
stoichiometry: 1.0
species: 900764
type: SpeciesReference

921687
stoichiometry: 1.0
species: 881065
type: SpeciesReference

966419
stoichiometry: 1.0
species: 896607
type: SpeciesReference

906343
fast: false
reversible: false
is: http://identifiers.org/ec-code/3.1.4.17
reactant: 958489
product: 958549
reactant: 958453
reactant: 958441
is: ENSPTRG00000015431.3
reactant: 958477
product: 958537
product: 958513
notes: R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PPCOACm subsystem: Valine, Leucine, and Isoleucine Metabolism R_PPCOACm equation: [m] : atp + hco3 + ppcoa --> adp + h + mmcoa-S + pi
product: 958561
type: Reaction
product: 958525
product: 958501
reactant: 958465
is: http://identifiers.org/ec-code/6.4.1.3

900425
product: 908874
product: 908850
type: Reaction
notes: R_PDHm subsystem: Glycolysis/Gluconeogenesis R_PDHm equation: [m] : coa + nad + pyr --> accoa + co2 + nadh R_2OXOADOXm subsystem: Lysine Metabolism R_2OXOADOXm equation: [m] : 2oxoadp + coa + nad --> co2 + glutcoa + nadh R_AKGDm subsystem: Citric Acid Cycle R_AKGDm equation: [m] : akg + coa + nad --> co2 + nadh + succoa
reactant: 908838
reversible: false
product: 908886
is: http://identifiers.org/ec-code/1.2.4.2
fast: false
reactant: 908825
reactant: 908813
product: 908862
product: 908898
is: http://identifiers.org/ec-code/1.2.4.1
reactant: 908789
reactant: 908801
is: ENSPTRG00000003500.3

003162
stoichiometry: 1.0
species: 897492
type: SpeciesReference

955208
stoichiometry: 1.0
species: 902318
type: SpeciesReference

905178
stoichiometry: 1.0
species: 890216
type: SpeciesReference

947821
stoichiometry: 1.0
species: 880788
type: SpeciesReference

877938
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Methylimidazole acetaldehyde_C6H8N2O
type: Species

904212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Xanthine_C5H4N4O2
type: Species

898985
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Adenosine 3',5'-bisphosphate_C10H11N5O10P2
type: Species

952684
stoichiometry: 1.0
species: 902788
type: SpeciesReference

935373
stoichiometry: 3.0
species: 892110
type: SpeciesReference

003920
stoichiometry: 2.0
species: 893756
type: SpeciesReference

963018
stoichiometry: 1.0
species: 889118
type: SpeciesReference

939029
stoichiometry: 1.0
species: 903137
type: SpeciesReference

881451
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: adrenyl coenzyme A_C43H66N7O17P3S
type: Species

886203
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: debrisoquine_C10H14N3
type: Species

883264
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: cervonyl coenzyme A_C43H62N7O17P3S
type: Species

935891
stoichiometry: 8.0
species: 891591
type: SpeciesReference

907834
product: 970697
is: http://identifiers.org/ec-code/1.2.1.5
reactant: 970503
type: Reaction
modifier: 970830
reactant: 970600
modifier: 970926
reactant: 970515
modifier: 970842
fast: false
product: 970758
modifier: 970854
reactant: 970527
modifier: 970866
reactant: 970539
modifier: 970794
product: 970782
is: ENSPTRG00000007508.4
reactant: 970576
product: 970685
is: http://identifiers.org/ec-code/1.2.1.3
reactant: 970588
modifier: 970902
product: 970733
reactant: 970612
product: 970649
modifier: 970914
is: http://identifiers.org/ec-code/1.2.1.39
reactant: 970624
modifier: 970890
modifier: 970806
product: 970746
product: 970770
modifier: 970818
product: 970636
modifier: 970878
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_34DHXMANDACOX subsystem: Tyrosine metabolism R_34DHXMANDACOX equation: [c] : 34dhmald + h2o + nad --> 34dhoxmand + (2) h + nadh
product: 970673
product: 970661
reactant: 970491
reactant: 970479
product: 970721
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 970552
reversible: false
reactant: 970564
product: 970709

972565
stoichiometry: 1.0
species: 900653
type: SpeciesReference

903307
reactant: 930628
reactant: 930616
type: Reaction
fast: false
notes: R_CHOLt4 subsystem: Transport, Extracellular R_CHOLt4 equation: chol[e] + na1[e] <==> chol[c] + na1[c]
reversible: true
is: ENSPTRG00000012325.3
name: choline, sodium cotransport
product: 930640
product: 930652

945905
stoichiometry: 1.0
species: 884451
type: SpeciesReference

943258
stoichiometry: 1.0
species: 888188
type: SpeciesReference

995094
stoichiometry: 1.0
species: 882541
type: SpeciesReference

908013
stoichiometry: 2.0
species: 878595
type: SpeciesReference

953628
stoichiometry: 1.0
species: 884061
type: SpeciesReference

942668
stoichiometry: 2.0
species: 899650
type: SpeciesReference

909753
reactant: 988700
reactant: 988736
product: 988796
reactant: 988712
is: http://identifiers.org/ec-code/1.2.1.3
product: 988833
product: 988893
product: 988869
product: 988857
product: 988784
product: 988772
fast: false
product: 988821
product: 988748
reactant: 988676
type: Reaction
reactant: 988592
product: 988760
product: 988881
product: 988845
reactant: 988652
reactant: 988688
is: ENSPTRG00000021023.4
reactant: 988664
reactant: 988616
product: 988808
reactant: 988640
reactant: 988628
notes: R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
is: http://identifiers.org/ec-code/1.2.1.21
reactant: 988724
reversible: false
reactant: 988604

993030
stoichiometry: 2.0
species: 903596
type: SpeciesReference

950568
stoichiometry: 5.0
species: 886275
type: SpeciesReference

924136
stoichiometry: 1.0
species: 882613
type: SpeciesReference

944845
stoichiometry: 4.0
species: 891519
type: SpeciesReference

904104
is: http://identifiers.org/ec-code/1.3.99.3
fast: false
notes: R_PPCOAOm subsystem: Propanoate Metabolism R_PPCOAOm equation: [m] : fad + ppcoa --> fadh2 + prpncoa R_ACOAD1fm subsystem: Butanoate Metabolism R_ACOAD1fm equation: [m] : btcoa + fad --> b2coa + fadh2
is: ENSPTRG00000015362.3
reversible: false
reactant: 936940
is: ENSPTRG00000005462.3
reactant: 936928
is: http://identifiers.org/ec-code/1.3.99.2
type: Reaction
product: 936964
reactant: 936916
product: 936976
product: 936952

994201
stoichiometry: 1.0
species: 884584
type: SpeciesReference

914958
stoichiometry: 1.0
species: 887217
type: SpeciesReference

978883
stoichiometry: 1.0
species: 901814
type: SpeciesReference

900630
reversible: false
reactant: 910620
is: ENSPTRG00000003079.4
is: ENSPTRG00000013050.4
is: ENSPTRG00000004031.5
product: 910644
is: http://identifiers.org/ec-code/3.1.3.56
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_MI145PP subsystem: Inositol Phosphate Metabolism R_MI145PP equation: [c] : h2o + mi145p --> mi14p + pi R_MI1345PP subsystem: Inositol Phosphate Metabolism R_MI1345PP equation: [c] : h2o + mi1345p --> mi134p + pi
product: 910668
fast: false
reactant: 910608
is: ENSPTRG00000014262.4
type: Reaction
reactant: 910596
product: 910632
reactant: 910584
product: 910656

924281
stoichiometry: 1.0
species: 895749
type: SpeciesReference

948439
stoichiometry: 1.0
species: 900436
type: SpeciesReference

005911
stoichiometry: 2.0
species: 899831
type: SpeciesReference

907833
stoichiometry: 1.0
species: 881463
type: SpeciesReference

895314
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: lignocericyl coenzyme A_C45H78N7O17P3S
type: Species

978145
stoichiometry: 1.0
species: 902463
type: SpeciesReference

993271
stoichiometry: 1.0
species: 890554
type: SpeciesReference

950230
stoichiometry: 1.0
species: 884158
type: SpeciesReference

931824
stoichiometry: 1.0
species: 891748
type: SpeciesReference

936592
stoichiometry: 1.0
species: 902776
type: SpeciesReference

881776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _2-Oxoglutarate_C5H4O5
type: Species

907099
stoichiometry: 8.0
species: 897261
type: SpeciesReference

000771
stoichiometry: 18.0
species: 891640
type: SpeciesReference

970322
stoichiometry: 1.0
species: 896667
type: SpeciesReference

954581
stoichiometry: 1.0
species: 882745
type: SpeciesReference

984376
stoichiometry: 1.0
species: 891555
type: SpeciesReference

905176
name: phosphatidyl-CMP: glycerophosphate phosphatidyltransferase
is: ENSPTRG00000009710.4
product: 945676
reactant: 945640
reversible: false
is: http://identifiers.org/ec-code/2.7.8.11
product: 945664
notes: R_PGPPT subsystem: Glycerophospholipid Metabolism R_PGPPT equation: [c] : cdpdag_hs + glyc3p --> cmp + h + pgp_hs
type: Reaction
fast: false
reactant: 945628
product: 945652

883494
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Carbamoyl phosphate_CH2NO5P
type: Species

979859
stoichiometry: 1.0
species: 903488
type: SpeciesReference

897900
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Norepinephrine_C8H12NO3
type: Species

966203
stoichiometry: 1.0
species: 897732
type: SpeciesReference

910318
is: ENSPTRG00000005789.1
reactant: 993042
product: 993078
is: http://identifiers.org/ec-code/2.4.1.117
reversible: false
product: 993090
notes: R_UDPDOLPT_L subsystem: N-Glycan Biosynthesis R_UDPDOLPT_L equation: [c] : (0.1) dolp_L + udpg --> (0.1) dolglcp_L + udp R_UDPDOLPT_U subsystem: N-Glycan Biosynthesis R_UDPDOLPT_U equation: [c] : (0.1) dolp_U + udpg --> (0.1) dolglcp_U + udp
product: 993066
type: Reaction
reactant: 993054
reactant: 993030
fast: false

948026
stoichiometry: 1.0
species: 882541
type: SpeciesReference

889638
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Gal-Gal-Gal-Gal-Glc-Cer (homo sapiens)_C48H86NO27FULLRCO
type: Species

987410
stoichiometry: 2.0
species: 896004
type: SpeciesReference

965450
stoichiometry: 1.0
species: 903596
type: SpeciesReference

961775
stoichiometry: 1.0
species: 898840
type: SpeciesReference

957367
stoichiometry: 1.0
species: 877468
type: SpeciesReference

004545
stoichiometry: 1.0
species: 889827
type: SpeciesReference

991256
stoichiometry: 1.0
species: 894771
type: SpeciesReference

893960
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: keratan sulfate I_C247H393N17O213S12X
type: Species

903305
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: tetracosanoyl-CoA (n-C24:0CoA)_C45H78N7O17P3S
type: Species

896825
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3
type: Species

895460
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Linoelaidyl carnitine_C25H45NO4
type: Species

934361
stoichiometry: 8.0
species: 891640
type: SpeciesReference

954471
stoichiometry: 4.0
species: 897261
type: SpeciesReference

968184
stoichiometry: 5.0
species: 903452
type: SpeciesReference

898140
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Superoxide anion_O2
type: Species

908015
modifier: 973459
product: 973169
modifier: 973386
product: 973266
reactant: 972903
modifier: 973350
product: 973181
product: 972976
is: ENSPTRG00000020587.4
is: ENSPTRG00000008467.3
modifier: 973435
reactant: 972819
reactant: 972952
reactant: 972662
reactant: 972723
product: 973085
product: 972988
reactant: 972928
reactant: 972686
reactant: 972771
modifier: 973326
product: 973097
reactant: 972867
product: 973133
product: 973061
modifier: 973495
product: 973241
reactant: 972891
product: 973145
product: 973073
modifier: 973302
modifier: 973531
product: 973253
modifier: 973507
modifier: 973471
product: 973012
is: http://identifiers.org/ec-code/3.2.1.18
modifier: 973362
product: 973025
reactant: 972759
reactant: 972843
is: http://identifiers.org/ec-code/3.2.1.23
modifier: 973447
product: 973037
is: http://identifiers.org/ec-code/3.1.6.4
reactant: 972783
modifier: 973411
type: Reaction
reactant: 972879
product: 973205
product: 973109
modifier: 973423
modifier: 973338
product: 973217
fast: false
notes: R_SIAASE3ly subsystem: Keratan sulfate degradation R_SIAASE3ly equation: [l] : h2o + ksii_core2 --> acnam + ksii_core2_deg1 R_LACZly subsystem: Galactose metabolism R_LACZly equation: [l] : h2o + lcts --> gal + glc-D R_GALASE5ly subsystem: Keratan sulfate degradation R_GALASE5ly equation: [l] : h2o + ksi_deg11 --> gal + ksi_deg12 R_GALASE1ly subsystem: N-Glycan Degradation R_GALASE1ly equation: [l] : (2) h2o + l2n2m2mn --> (2) gal + n2m2mn R_S6TASE9ly subsystem: Chondroitin sulfate degradation R_S6TASE9ly equation: [l] : cs_e_deg5 + h2o <==> cs_e_deg6 + h + so4 R_S6TASE25ly subsystem: Keratan sulfate degradation R_S6TASE25ly equation: [l] : h2o + ksii_core4_deg1 <==> h + ksii_core4_deg2 + so4 R_GLB1 subsystem: Sphingolipid Metabolism R_GLB1 equation: [l] : galgluside_hs + h2o --> gal + gluside_hs R_GALASE13ly subsystem: Keratan sulfate degradation R_GALASE13ly equation: [l] : h2o + ksi_deg35 --> gal + ksi_deg36 R_S6TASE10ly subsystem: Keratan sulfate degradation R_S6TASE10ly equation: [l] : h2o + ksi_deg4 <==> h + ksi_deg5 + so4 R_GALASE17ly subsystem: Keratan sulfate degradation R_GALASE17ly equation: [l] : h2o + ksii_core2_deg5 --> gal + ksii_core2_deg6 R_GALASE6ly subsystem: Keratan sulfate degradation R_GALASE6ly equation: [l] : h2o + ksi_deg14 --> gal + ksi_deg15 R_GALASE11ly subsystem: Keratan sulfate degradation R_GALASE11ly equation: [l] : h2o + ksi_deg29 --> gal + ksi_deg30 R_GALASE3ly subsystem: Keratan sulfate degradation R_GALASE3ly equation: [l] : (2) h2o + ksi_deg5 --> (2) gal + ksi_deg6 R_S6TASE5ly subsystem: Chondroitin sulfate degradation R_S6TASE5ly equation: [l] : cs_c_deg3 + h2o <==> cs_c_deg4 + h + so4 R_GALASE19ly subsystem: Keratan sulfate degradation R_GALASE19ly equation: [l] : f1a + h2o --> core6 + gal R_SIAASE2ly subsystem: Keratan sulfate degradation R_SIAASE2ly equation: [l] : h2o + ksi_deg3 --> acnam + ksi_deg4 R_S6TASE22ly subsystem: Keratan sulfate degradation R_S6TASE22ly equation: [l] : h2o + ksii_core2_deg1 <==> h + ksii_core2_deg2…
reversible: false
reactant: 972735
modifier: 973483
is: ENSPTRG00000016090.3
modifier: 973398
reactant: 972916
reactant: 972855
modifier: 973519
reactant: 972964
reactant: 972674
modifier: 973374
reactant: 972699
product: 973049
product: 973278
product: 973193
reactant: 972711
product: 973290
product: 973121
modifier: 973314
modifier: 973543
product: 973229
reactant: 972747
reactant: 972831
reactant: 972807

003812
stoichiometry: 1.0
species: 891688
type: SpeciesReference

928769
stoichiometry: 4.0
species: 897261
type: SpeciesReference

980016
stoichiometry: 1.0
species: 891664
type: SpeciesReference

928660
stoichiometry: 1.0
species: 880111
type: SpeciesReference

917358
stoichiometry: 3.0
species: 881885
type: SpeciesReference

004269
stoichiometry: 2.0
species: 899530
type: SpeciesReference

936448
stoichiometry: 1.0
species: 877191
type: SpeciesReference

905236
product: 946182
reactant: 946158
is: http://identifiers.org/ec-code/4.1.1.19
notes: R_ARGDCm subsystem: Arginine and Proline Metabolism R_ARGDCm equation: [m] : arg-L + h --> agm + co2
name: arginine decarboxylase (m)
fast: false
reversible: false
type: Reaction
reactant: 946146
product: 946170
is: ENSPTRG00000000501.3

996546
stoichiometry: 1.0
species: 887703
type: SpeciesReference

933552
stoichiometry: 1.0
species: 891616
type: SpeciesReference

906691
is: http://identifiers.org/ec-code/2.8.2.23
type: Reaction
product: 961017
product: 961005
fast: false
is: ENSPTRG00000007881.3
reactant: 960980
notes: R_S3T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T2g equation: [g] : hs_pre14 + paps --> h + hs_pre15 + pap
reversible: false
product: 960992
name: heparin-glucosamine 3-O-sulfotransferase
reactant: 960968

919233
stoichiometry: 1.0
species: 899009
type: SpeciesReference

918290
stoichiometry: 1.0
species: 877770
type: SpeciesReference

952261
stoichiometry: 3.0
species: 901814
type: SpeciesReference

999500
stoichiometry: 1.0
species: 894963
type: SpeciesReference

922758
stoichiometry: 18.0
species: 903452
type: SpeciesReference

905926
stoichiometry: 1.0
species: 898985
type: SpeciesReference

944953
stoichiometry: 1.0
species: 890506
type: SpeciesReference

976284
stoichiometry: 1.0
species: 891591
type: SpeciesReference

887339
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dopaquinone_C9H9NO4
type: Species

951162
stoichiometry: 1.0
species: 879691
type: SpeciesReference

948892
stoichiometry: 1.0
species: 894663
type: SpeciesReference

911014
modifier: 999055
notes: R_ALCD22_D subsystem: Pyruvate Metabolism R_ALCD22_D equation: [c] : lald-D + nad --> h + mthgxl + nadh R_34DHOXPEGOX subsystem: Tyrosine metabolism R_34DHOXPEGOX equation: [c] : 34dhmald + h + nadh <==> 34dhoxpeg + nad R_ALCD1 subsystem: Miscellaneous R_ALCD1 equation: [c] : meoh + nad <==> fald + h + nadh R_ALCD2if subsystem: Glycolysis/Gluconeogenesis R_ALCD2if equation: [c] : etoh + nad --> acald + h + nadh R_ALCD21_D subsystem: Pyruvate Metabolism R_ALCD21_D equation: [c] : 12ppd-R + nad --> h + lald-D + nadh R_ALCD22_L subsystem: Pyruvate Metabolism R_ALCD22_L equation: [c] : lald-L + nad --> h + mthgxl + nadh R_ALCD21_L subsystem: Pyruvate Metabolism R_ALCD21_L equation: [c] : 12ppd-S + nad --> h + lald-L + nadh
is: ENSPTRG00000023060.3
is: ENSPTRG00000023494.3
reactant: 998874
is: ENSPTRG00000020307.2
modifier: 999031
product: 998922
reactant: 998898
is: ENSPTRG00000002729.5
is: http://identifiers.org/ec-code/1.1.1.1
product: 998910
reactant: 998862
modifier: 998983
is: http://identifiers.org/ec-code/1.1.1.78
reversible: false
product: 998946
reactant: 998838
modifier: 998995
modifier: 999007
product: 998959
product: 998934
is: ENSPTRG00000024240.2
reactant: 998886
is: ENSPTRG00000009762.4
fast: false
product: 998971
modifier: 999043
type: Reaction
reactant: 998850
is: http://identifiers.org/ec-code/1.2.1.49
modifier: 999019

939739
stoichiometry: 1.0
species: 901573
type: SpeciesReference

947978
stoichiometry: 3.0
species: 888382
type: SpeciesReference

904103
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Valine_C5H11NO2
type: Species

005167
stoichiometry: 1.0
species: 886841
type: SpeciesReference

879775
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Histone N6-methyl-L-lysine_CXH4
type: Species

889935
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GD1c (homo sapiens)_C66H111N4O38FULLRCO
type: Species

939691
stoichiometry: 1.0
species: 891591
type: SpeciesReference

902342
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: tetracosapentaenoic acid, n-3_C24H37O2
type: Species

009417
stoichiometry: 3.0
species: 885550
type: SpeciesReference

964765
stoichiometry: 9.0
species: 897261
type: SpeciesReference

986771
stoichiometry: 1.0
species: 881885
type: SpeciesReference

006807
stoichiometry: 1.0
species: 883374
type: SpeciesReference

959342
stoichiometry: 1.0
species: 879041
type: SpeciesReference

876996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _1-Pyrroline-2-carboxylate_C5H6NO2
type: Species

943631
stoichiometry: 1.0
species: 891664
type: SpeciesReference

986555
stoichiometry: 1.0
species: 896475
type: SpeciesReference

996762
stoichiometry: 1.0
species: 895350
type: SpeciesReference

005441
stoichiometry: 1.0
species: 900352
type: SpeciesReference

983772
stoichiometry: 6.0
species: 891483
type: SpeciesReference

972819
stoichiometry: 1.0
species: 894480
type: SpeciesReference

900848
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: fatty acid retinol_C20H29OFULLR2CO
type: Species

900533
product: 909675
reversible: false
product: 909736
is: ENSPTRG00000015718.4
product: 909651
reactant: 909590
product: 909699
fast: false
reactant: 909578
product: 909748
product: 909724
reactant: 909639
reactant: 909602
product: 909663
notes: R_HSD3B3r subsystem: Steroid Metabolism R_HSD3B3r equation: [r] : eandrstrn + h + nadph --> andrstandn + h2o + nadp R_HSD3B2r subsystem: Steroid Metabolism R_HSD3B2r equation: [r] : eandrstrn + h + nadh --> andrstandn + h2o + nad R_HSD3B11r subsystem: Steroid Metabolism R_HSD3B11r equation: [r] : nad + prgnlone --> h + nadh + prgstrn R_HSD3B12r subsystem: Steroid Metabolism R_HSD3B12r equation: [r] : dhea + nad --> andrstndn + h + nadh R_HSD3B13r subsystem: Steroid Metabolism R_HSD3B13r equation: [r] : 17ahprgnlone + nad --> 17ahprgstrn + h + nadh
reactant: 909554
reactant: 909614
type: Reaction
product: 909687
reactant: 909566
reactant: 909626
product: 909712

884995
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate C (GalNAc6S-GlcA) and D (GlcNAc6S-GlcA2S), precursor 1_C31H47NO31S2X
type: Species

927392
stoichiometry: 1.0
species: 878505
type: SpeciesReference

935637
stoichiometry: 1.0
species: 896728
type: SpeciesReference

948700
stoichiometry: 1.0
species: 897528
type: SpeciesReference

949400
stoichiometry: 1.0
species: 881258
type: SpeciesReference

979546
stoichiometry: 1.0
species: 898768
type: SpeciesReference

887703
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: dUTP_C9H11N2O14P3
type: Species

891074
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Geranyl diphosphate_C10H17O7P2
type: Species

902343
product: 923714
reversible: true
notes: R_FRUt1r subsystem: Transport, Extracellular R_FRUt1r equation: fru[e] <==> fru[c] R_GALt1r subsystem: Transport, Extracellular R_GALt1r equation: gal[e] <==> gal[c] R_GLCt1r subsystem: Transport, Extracellular R_GLCt1r equation: glc-D[e] <==> glc-D[c]
fast: false
product: 923726
reactant: 923690
product: 923702
type: Reaction
reactant: 923666
is: ENSPTRG00000021387.5
reactant: 923678

010654
stoichiometry: 1.0
species: 878216
type: SpeciesReference

994878
stoichiometry: 2.0
species: 898080
type: SpeciesReference

979811
stoichiometry: 1.0
species: 896631
type: SpeciesReference

009971
stoichiometry: 1.0
species: 892183
type: SpeciesReference

008451
stoichiometry: 1.0
species: 884391
type: SpeciesReference

001257
stoichiometry: 2.0
species: 897261
type: SpeciesReference

914510
stoichiometry: 1.0
species: 901130
type: SpeciesReference

900847
reactant: 911637
reactant: 911613
product: 911734
reactant: 911661
type: Reaction
is: ENSPTRG00000023914.2
reactant: 911601
reactant: 911625
product: 911746
product: 911685
reactant: 911673
reversible: false
notes: R_THMDt5 subsystem: Transport, Extracellular R_THMDt5 equation: (2) na1[e] + thymd[e] --> (2) na1[c] + thymd[c] R_CYTDt4 subsystem: Transport, Extracellular R_CYTDt4 equation: cytd[e] + na1[e] --> cytd[c] + na1[c] R_URIt5 subsystem: Transport, Extracellular R_URIt5 equation: (2) na1[e] + uri[e] --> (2) na1[c] + uri[c] R_GSNt5 subsystem: Transport, Extracellular R_GSNt5 equation: gsn[e] + (2) na1[e] --> gsn[c] + (2) na1[c] R_CYTDt5 subsystem: Transport, Extracellular R_CYTDt5 equation: cytd[e] + (2) na1[e] --> cytd[c] + (2) na1[c] R_INSt5 subsystem: Transport, Extracellular R_INSt5 equation: ins[e] + (2) na1[e] --> ins[c] + (2) na1[c] R_ADNt4 subsystem: Transport, Extracellular R_ADNt4 equation: adn[e] + na1[e] --> adn[c] + na1[c] R_URIt4 subsystem: Transport, Extracellular R_URIt4 equation: na1[e] + uri[e] --> na1[c] + uri[c] R_THMDt4 subsystem: Transport, Extracellular R_THMDt4 equation: na1[e] + thymd[e] --> na1[c] + thymd[c] R_INSt4 subsystem: Transport, Extracellular R_INSt4 equation: ins[e] + na1[e] --> ins[c] + na1[c] R_GSNt4 subsystem: Transport, Extracellular R_GSNt4 equation: gsn[e] + na1[e] --> gsn[c] + na1[c] R_ADNt5 subsystem: Transport, Extracellular R_ADNt5 equation: adn[e] + (2) na1[e] --> adn[c] + (2) na1[c]
reactant: 911649
product: 911758
product: 911722
product: 911710
product: 911697
fast: false

000061
stoichiometry: 2.0
species: 891495
type: SpeciesReference

976850
stoichiometry: 3.0
species: 885731
type: SpeciesReference

929106
stoichiometry: 1.0
species: 903897
type: SpeciesReference

977784
stoichiometry: 1.0
species: 883251
type: SpeciesReference

900532
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: pentadecanoyl Coenzyme A_C36H60N7O17P3S
type: Species

977627
stoichiometry: 1.0
species: 892729
type: SpeciesReference

896523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Methanol_CH4O1
type: Species

954799
stoichiometry: 2.0
species: 897261
type: SpeciesReference

986156
stoichiometry: 2.0
species: 897443
type: SpeciesReference

959119
stoichiometry: 1.0
species: 889827
type: SpeciesReference

919884
stoichiometry: 1.0
species: 878715
type: SpeciesReference

899892
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6
type: Species

917514
stoichiometry: 2.0
species: 899795
type: SpeciesReference

952479
stoichiometry: 1.0
species: 887302
type: SpeciesReference

919148
stoichiometry: 1.0
species: 882384
type: SpeciesReference

899787
type: Reaction
name: lipase
reversible: false
notes: R_LPS3 subsystem: Triacylglycerol Synthesis R_LPS3 equation: [c] : h2o + mag_hs --> Rtotal2 + glyc + h
reactant: 904801
product: 904837
is: ENSPTRG00000015348.3
is: http://identifiers.org/ec-code/3.1.1.23
product: 904825
product: 904813
fast: false
reactant: 904789

909981
reactant: 991701
product: 991785
product: 991749
notes: R_NKCCt subsystem: Transport, Extracellular R_NKCCt equation: (2) cl[e] + k[e] + na1[e] <==> (2) cl[c] + k[c] + na1[c] R_NKCC2t subsystem: Transport, Extracellular R_NKCC2t equation: (2) cl[e] + na1[e] + nh4[e] <==> (2) cl[c] + na1[c] + nh4[c]
reversible: true
reactant: 991713
reactant: 991737
reactant: 991725
is: ENSPTRG00000017199.4
is: ENSPTRG00000007043.5
product: 991773
fast: false
type: Reaction
product: 991761

970058
stoichiometry: 1.0
species: 897636
type: SpeciesReference

008731
stoichiometry: 4.0
species: 891591
type: SpeciesReference

942969
stoichiometry: 1.0
species: 897528
type: SpeciesReference

960062
stoichiometry: 1.0
species: 881282
type: SpeciesReference

970612
stoichiometry: 1.0
species: 895000
type: SpeciesReference

975002
stoichiometry: 1.0
species: 891591
type: SpeciesReference

949569
stoichiometry: 1.0
species: 885985
type: SpeciesReference

960811
stoichiometry: 1.0
species: 890020
type: SpeciesReference

932018
stoichiometry: 2.0
species: 898600
type: SpeciesReference

975474
stoichiometry: 1.0
species: 886227
type: SpeciesReference

971190
stoichiometry: 1.0
species: 897237
type: SpeciesReference

910319
stoichiometry: 1.0
species: 898804
type: SpeciesReference

885937
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dCMP_C9H12N3O7P
type: Species

944424
stoichiometry: 15.0
species: 891507
type: SpeciesReference

890008
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: GDP_C10H12N5O11P2
type: Species

884645
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: ceramide (homo sapiens)_C18H36NO2FULLRCO
type: Species

905239
stoichiometry: 1.0
species: 893199
type: SpeciesReference

911018
stoichiometry: 1.0
species: 901366
type: SpeciesReference

933844
stoichiometry: 1.0
species: 890362
type: SpeciesReference

894212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 27_C205H328N14O171S8X
type: Species

909980
stoichiometry: 1.0
species: 887739
type: SpeciesReference

981711
stoichiometry: 1.0
species: 878993
type: SpeciesReference

886384
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Deoxyguanosine_C10H13N5O4
type: Species

930797
stoichiometry: 1.0
species: 883167
type: SpeciesReference

937545
stoichiometry: 1.0
species: 888490
type: SpeciesReference

909082
stoichiometry: 3.0
species: 881258
type: SpeciesReference

884790
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: cervonic acid, C22:6 n-3_C22H31O2
type: Species

880183
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: T antigen (core 1)_C14H24NO10X
type: Species

942267
stoichiometry: 1.0
species: 898660
type: SpeciesReference

958938
stoichiometry: 1.0
species: 897261
type: SpeciesReference

882493
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: arachidonic acid_C20H31O2
type: Species

984724
stoichiometry: 1.0
species: 890326
type: SpeciesReference

989389
stoichiometry: 1.0
species: 895000
type: SpeciesReference

949845
stoichiometry: 1.0
species: 900532
type: SpeciesReference

998706
stoichiometry: 1.0
species: 894092
type: SpeciesReference

909081
modifier: 982794
reactant: 982662
product: 982698
modifier: 982746
modifier: 982770
reactant: 982614
is: http://identifiers.org/ec-code/2.6.1.21
is: ENSPTRG00000008185.3
modifier: 982806
modifier: 982758
modifier: 982722
is: http://identifiers.org/ec-code/2.6.1.1
notes: R_EHGLAT2m subsystem: Arginine and Proline Metabolism R_EHGLAT2m equation: [m] : e4hglu + oaa --> 4h2oglt + asp-L R_TYRTAm subsystem: Tyrosine metabolism R_TYRTAm equation: [m] : akg + tyr-L <==> 34hpp + glu-L R_PHETA1m subsystem: Phenylalanine metabolism R_PHETA1m equation: [m] : akg + phe-L <==> glu-L + phpyr R_LCYSTATm subsystem: Cysteine Metabolism R_LCYSTATm equation: [m] : Lcyst + akg <==> 3spyr + glu-L R_CYSTAm subsystem: Cysteine Metabolism R_CYSTAm equation: [m] : akg + cys-L <==> glu-L + mercppyr R_ASPTAm subsystem: Alanine and Aspartate Metabolism R_ASPTAm equation: [m] : akg + asp-L <==> glu-L + oaa R_EHGLATm subsystem: Arginine and Proline Metabolism R_EHGLATm equation: [m] : akg + e4hglu --> 4h2oglt + glu-L R_3SALATAim subsystem: Cysteine Metabolism R_3SALATAim equation: [m] : 3sala + akg + h --> 3snpyr + glu-L
modifier: 982830
modifier: 982782
reactant: 982626
product: 982710
modifier: 982734
reversible: false
modifier: 982842
fast: false
is: http://identifiers.org/ec-code/2.6.1.5
product: 982674
product: 982686
modifier: 982818
reactant: 982638
is: http://identifiers.org/ec-code/2.6.1.58
reactant: 982650
modifier: 982854
is: http://identifiers.org/ec-code/2.6.1.3
type: Reaction

988144
stoichiometry: 3.0
species: 890518
type: SpeciesReference

969112
stoichiometry: 1.0
species: 885635
type: SpeciesReference

969413
stoichiometry: 1.0
species: 881294
type: SpeciesReference

933769
stoichiometry: 1.0
species: 891483
type: SpeciesReference

955992
stoichiometry: 1.0
species: 892085
type: SpeciesReference

898104
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Superoxide anion_O2
type: Species

893406
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: potassium_K
type: Species

890252
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: D-Glucuronate_C6H9O7
type: Species

902223
reactant: 922383
reactant: 922335
type: Reaction
product: 922469
reactant: 922371
product: 922529
product: 922577
notes: R_THRt4 subsystem: Transport, Extracellular R_THRt4 equation: na1[e] + thr-L[e] --> na1[c] + thr-L[c] R_HISt4 subsystem: Transport, Extracellular R_HISt4 equation: his-L[e] + na1[e] --> his-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_METt4 subsystem: Transport, Extracellular R_METt4 equation: met-L[e] + na1[e] --> met-L[c] + na1[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
product: 922553
reactant: 922419
product: 922589
reactant: 922407
is: ENSPTRG00000004856.5
product: 922565
product: 922505
product: 922481
reversible: false
reactant: 922431
product: 922517
reactant: 922456
product: 922493
reactant: 922359
product: 922541
fast: false
reactant: 922444
reactant: 922395
reactant: 922347

968136
stoichiometry: 2.0
species: 897516
type: SpeciesReference

954411
stoichiometry: 1.0
species: 901103
type: SpeciesReference

903197
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Testosterone_C19H28O2
type: Species

933673
stoichiometry: 2.0
species: 891664
type: SpeciesReference

879631
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-2-Aminoadipate_C6H10NO4
type: Species

927693
stoichiometry: 1.0
species: 876740
type: SpeciesReference

901169
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: sialyl-T antigen_C25H40N2O18X
type: Species

895761
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Lysine_C6H15N2O2
type: Species

927548
stoichiometry: 1.0
species: 897504
type: SpeciesReference

892183
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
type: Species

908534
is: http://identifiers.org/ec-code/2.7.4.3
product: 979245
reactant: 979221
fast: false
product: 979281
type: Reaction
product: 979257
product: 979293
reactant: 979209
reactant: 979185
reactant: 979197
reactant: 979161
reactant: 979233
is: ENSPTRG00000000880.4
notes: R_ADK1 subsystem: Nucleotides R_ADK1 equation: [c] : amp + atp <==> (2) adp R_ADK3 subsystem: Nucleotides R_ADK3 equation: [c] : amp + gtp <==> adp + gdp R_CYTK4 subsystem: Nucleotides R_CYTK4 equation: [c] : dcmp + gtp <==> dcdp + gdp R_CYTK3 subsystem: Nucleotides R_CYTK3 equation: [c] : cmp + gtp <==> cdp + gdp R_ADKd subsystem: Nucleotides R_ADKd equation: [c] : damp + datp <==> (2) dadp
reactant: 979173
product: 979269
reversible: true

001377
stoichiometry: 1.0
species: 883058
type: SpeciesReference

007314
stoichiometry: 1.0
species: 879811
type: SpeciesReference

972239
stoichiometry: 1.0
species: 894056
type: SpeciesReference

885756
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2
type: Species

899432
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: O-Phospho-L-homoserine_C4H8NO6P
type: Species

884379
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Carbon monoxide_CO
type: Species

952528
stoichiometry: 1.0
species: 885876
type: SpeciesReference

985528
stoichiometry: 1.0
species: 886624
type: SpeciesReference

895436
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: linoelaidyl coenzyme A_C39H62N7O17P3S
type: Species

978289
stoichiometry: 1.0
species: 883289
type: SpeciesReference

967086
stoichiometry: 1.0
species: 889839
type: SpeciesReference

003571
stoichiometry: 1.0
species: 894468
type: SpeciesReference

896704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: mannosyl-glucosaminyl-acylphosphatidylinositiol (H2)_C37H68NO19PFULLRCO2FULLR2CO2
type: Species

894164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 23_C185H296N13O153S7X
type: Species

009875
stoichiometry: 1.0
species: 891050
type: SpeciesReference

881017
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Acetylneuraminate 9-phosphate_C11H17NO12P
type: Species

942509
stoichiometry: 1.0
species: 881463
type: SpeciesReference

999332
stoichiometry: 1.0
species: 900715
type: SpeciesReference

915693
stoichiometry: 1.0
species: 882781
type: SpeciesReference

952381
stoichiometry: 1.0
species: 896245
type: SpeciesReference

961571
stoichiometry: 1.0
species: 882529
type: SpeciesReference

905950
stoichiometry: 2.0
species: 891483
type: SpeciesReference

946642
stoichiometry: 1.0
species: 880486
type: SpeciesReference

987266
stoichiometry: 1.0
species: 898636
type: SpeciesReference

908535
stoichiometry: 2.0
species: 902030
type: SpeciesReference

886528
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
type: Species

883010
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Bilirubin monoglucuronide_C39H44N4O12
type: Species

880450
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Acetaldehyde_C2H4O
type: Species

009199
stoichiometry: 1.0
species: 878751
type: SpeciesReference

906616
stoichiometry: 1.0
species: 903476
type: SpeciesReference

009331
stoichiometry: 3.0
species: 885562
type: SpeciesReference

928647
stoichiometry: 1.0
species: 888974
type: SpeciesReference

007530
stoichiometry: 1.0
species: 886275
type: SpeciesReference

921325
stoichiometry: 1.0
species: 884451
type: SpeciesReference

921759
stoichiometry: 2.0
species: 891748
type: SpeciesReference

903814
is: ENSPTRG00000018739.5
reversible: false
is: http://identifiers.org/ec-code/3.1.3.36
type: Reaction
product: 934878
reactant: 934829
fast: false
notes: R_PI345P5P subsystem: Inositol Phosphate Metabolism R_PI345P5P equation: [c] : h2o + pail345p_hs --> pail34p_hs + pi R_PI45P5P subsystem: Inositol Phosphate Metabolism R_PI45P5P equation: [c] : h2o + pail45p_hs --> pail4p_hs + pi
reactant: 934841
reactant: 934853
product: 934866
product: 934890

950291
stoichiometry: 1.0
species: 904055
type: SpeciesReference

987530
stoichiometry: 1.0
species: 896004
type: SpeciesReference

920514
stoichiometry: 1.0
species: 890470
type: SpeciesReference

879390
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: _6-Pyruvoyl-5,6,7,8-tetrahydropterin_C9H11N5O3
type: Species

993090
stoichiometry: 1.0
species: 887193
type: SpeciesReference

953448
stoichiometry: 2.0
species: 889996
type: SpeciesReference

995829
stoichiometry: 1.0
species: 896269
type: SpeciesReference

907870
fast: false
product: 971118
product: 971106
notes: R_GLGNS1 subsystem: Starch and Sucrose Metabolism R_GLGNS1 equation: [c] : ggn + (3) udpg --> glygn1 + (3) h + (3) udp R_GGNG subsystem: Starch and Sucrose Metabolism R_GGNG equation: [c] : Tyr-ggn + (8) udpg --> ggn + (8) h + (8) udp
product: 971130
is: ENSPTRG00000015509.4
reactant: 971069
is: ENSPTRG00000004761.4
is: http://identifiers.org/ec-code/2.4.1.11
reactant: 971094
is: ENSPTRG00000011269.4
type: Reaction
reactant: 971082
reversible: false
product: 971142
is: ENSPTRG00000021625.4

884802
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate/heparan sulfate linkage region (GlcA-(Gal)2-Xyl-L-Ser (protein))_C23H36O20X
type: Species

004497
stoichiometry: 1.0
species: 888346
type: SpeciesReference

004040
stoichiometry: 2.0
species: 885164
type: SpeciesReference

951743
stoichiometry: 1.0
species: 891531
type: SpeciesReference

944881
stoichiometry: 1.0
species: 892413
type: SpeciesReference

920394
stoichiometry: 1.0
species: 884995
type: SpeciesReference

911158
product: 000163
is: http://identifiers.org/ec-code/3.2.1.21
is: ENSPTRG00000015953.3
reactant: 000138
name: beta-D-Glucosyl-2-coumarinate glucohydrolase
reactant: 000126
product: 000151
reversible: false
notes: R_BDG2HCGHD subsystem: Stilbene, coumarine and lignin biosynthesis R_BDG2HCGHD equation: [c] : bdg2hc + h2o --> 2coum + glc-D + h
type: Reaction
product: 000175
fast: false

947050
stoichiometry: 1.0
species: 900580
type: SpeciesReference

002328
stoichiometry: 2.0
species: 901414
type: SpeciesReference

964278
stoichiometry: 2.0
species: 891664
type: SpeciesReference

958321
stoichiometry: 1.0
species: 899530
type: SpeciesReference

970442
stoichiometry: 2.0
species: 881258
type: SpeciesReference

951959
stoichiometry: 1.0
species: 890566
type: SpeciesReference

918374
stoichiometry: 1.0
species: 897407
type: SpeciesReference

910740
stoichiometry: 1.0
species: 897395
type: SpeciesReference

953047
stoichiometry: 1.0
species: 901306
type: SpeciesReference

936568
stoichiometry: 1.0
species: 882781
type: SpeciesReference

937979
stoichiometry: 4.0
species: 897395
type: SpeciesReference

960750
stoichiometry: 1.0
species: 891640
type: SpeciesReference

006384
stoichiometry: 1.0
species: 891579
type: SpeciesReference

999731
stoichiometry: 1.0
species: 888502
type: SpeciesReference

881969
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: lysophosphatidic acid (homo sapiens)_C3H6O5PFULLRCO2
type: Species

883446
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Carbamoyl-L-aspartate_C5H6N2O5
type: Species

941022
stoichiometry: 1.0
species: 892110
type: SpeciesReference

904561
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Xanthosine_C10H12N4O6
type: Species

886889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dITP_C10H11N4O13P3
type: Species

885248
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 2_C45H66N2O49S4
type: Species

970370
stoichiometry: 1.0
species: 897528
type: SpeciesReference

979027
stoichiometry: 1.0
species: 891676
type: SpeciesReference

957391
stoichiometry: 1.0
species: 877890
type: SpeciesReference

950351
stoichiometry: 1.0
species: 895508
type: SpeciesReference

989195
stoichiometry: 1.0
species: 879643
type: SpeciesReference

913810
stoichiometry: 1.0
species: 884730
type: SpeciesReference

909321
fast: false
notes: R_GTHP subsystem: Glutathione Metabolism R_GTHP equation: [c] : (2) gthrd + h2o2 <==> gthox + (2) h2o
name: glutathione peridoxase
is: ENSPTRG00000010541.4
is: http://identifiers.org/ec-code/1.11.1.9
reactant: 984616
reversible: true
is: ENSPTRG00000000675.4
product: 984640
product: 984628
reactant: 984604
type: Reaction

905116
stoichiometry: 1.0
species: 892994
type: SpeciesReference

949701
stoichiometry: 1.0
species: 895484
type: SpeciesReference

929226
stoichiometry: 6.0
species: 897273
type: SpeciesReference

891206
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GT3 (homo sapiens)_C63H104N4O36FULLRCO
type: Species

904562
product: 941300
reactant: 941288
product: 941336
product: 941312
reversible: false
product: 941348
product: 941324
reactant: 941252
type: Reaction
product: 941372
reactant: 941240
notes: R_BTNt3i subsystem: Transport, Extracellular R_BTNt3i equation: atp[c] + btn[e] + h2o[c] + (2) na1[e] --> adp[c] + btn[c] + h[c] + (2) na1[c] + pi[c] R_LIPOti subsystem: Transport, Extracellular R_LIPOti equation: atp[c] + h2o[c] + lipoate[e] + (2) na1[e] --> adp[c] + h[c] + lipoate[c] + (2) na1[c] + pi[c] R_PNTOt5 subsystem: Transport, Extracellular R_PNTOt5 equation: atp[c] + h2o[c] + (2) na1[e] + pnto-R[e] --> adp[c] + h[c] + (2) na1[c] + pi[c] + pnto-R[c]
reactant: 941228
fast: false
reactant: 941276
product: 941360
is: ENSPTRG00000011754.2
reactant: 941264

995513
stoichiometry: 1.0
species: 882541
type: SpeciesReference

977202
stoichiometry: 6.0
species: 891616
type: SpeciesReference

986010
stoichiometry: 1.0
species: 881282
type: SpeciesReference

996497
stoichiometry: 1.0
species: 891591
type: SpeciesReference

903812
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Uroporphyrinogen III_C40H36N4O16
type: Species

897480
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3
type: Species

935180
stoichiometry: 10.0
species: 897395
type: SpeciesReference

894285
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 32_C227H362N16O192S10X
type: Species

965330
stoichiometry: 1.0
species: 896245
type: SpeciesReference

002182
stoichiometry: 1.0
species: 903464
type: SpeciesReference

932995
stoichiometry: 4.0
species: 898997
type: SpeciesReference

942824
stoichiometry: 2.0
species: 899783
type: SpeciesReference

961909
stoichiometry: 1.0
species: 891760
type: SpeciesReference

901270
product: 915235
reversible: false
name: pyruvate kinase
fast: false
notes: R_PYK subsystem: Glycolysis/Gluconeogenesis R_PYK equation: [c] : adp + h + pep --> atp + pyr
is: ENSPTRG00000001421.4
is: ENSPTRG00000000495.5
type: Reaction
reactant: 915211
is: http://identifiers.org/ec-code/2.7.1.40
reactant: 915199
reactant: 915187
product: 915223
is: ENSPTRG00000007246.4

930232
stoichiometry: 1.0
species: 891194
type: SpeciesReference

916443
stoichiometry: 1.0
species: 892293
type: SpeciesReference

902547
product: 925006
fast: false
reactant: 924958
reactant: 924946
reactant: 924910
reactant: 924982
product: 925031
reactant: 924934
notes: R_P4501B1r subsystem: Steroid Metabolism R_P4501B1r equation: [r] : estradiol + h + nadph + o2 --> h2o + hestratriol + nadp R_MELATNOX subsystem: Tryptophan metabolism R_MELATNOX equation: [c] : h + melatn + nadph + o2 --> 6hoxmelatn + h2o + nadp
reversible: false
product: 925043
is: ENSPTRG00000011843.2
is: http://identifiers.org/ec-code/1.14.14.1
reactant: 924922
type: Reaction
reactant: 924994
product: 925068
product: 925019
product: 925055
reactant: 924970

935517
stoichiometry: 1.0
species: 899856
type: SpeciesReference

904296
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3alpha,7alpha-Dihydroxy-5beta-cholestane_C27H48O2
type: Species

894915
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)2-Xyl-L-Ser (protein)_C17H29O14X
type: Species

988772
stoichiometry: 1.0
species: 893199
type: SpeciesReference

982289
stoichiometry: 1.0
species: 897492
type: SpeciesReference

992692
stoichiometry: 1.0
species: 901017
type: SpeciesReference

884500
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Core 3_C16H27N2O10X
type: Species

956196
stoichiometry: 1.0
species: 895641
type: SpeciesReference

000240
stoichiometry: 2.0
species: 881258
type: SpeciesReference

937424
stoichiometry: 1.0
species: 904152
type: SpeciesReference

930676
stoichiometry: 1.0
species: 892958
type: SpeciesReference

888950
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
type: Species

963614
stoichiometry: 5.0
species: 885562
type: SpeciesReference

945809
stoichiometry: 1.0
species: 892171
type: SpeciesReference

924714
stoichiometry: 1.0
species: 881728
type: SpeciesReference

888418
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2
type: Species

900727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Pyruvate_C3H3O3
type: Species

889202
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: glucosyl-(alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform C (protein)_C70H117N2O55X
type: Species

902548
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Tetracosatetraenoyl carnitine_C31H53NO4
type: Species

881801
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: beta-Alanine_C3H7NO2
type: Species

919764
stoichiometry: 1.0
species: 900764
type: SpeciesReference

901958
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: stearidonyl carnitine_C25H41NO4
type: Species

929686
stoichiometry: 2.0
species: 891664
type: SpeciesReference

904297
type: Reaction
product: 939284
is: http://identifiers.org/ec-code/3.6.1.13
reactant: 939259
product: 939320
is: http://identifiers.org/ec-code/3.6.1.21
reactant: 939247
reactant: 939235
product: 939296
reactant: 939223
reversible: false
notes: R_ADPGLC subsystem: Nucleotides R_ADPGLC equation: [c] : adpglc + h2o --> amp + g1p + (2) h R_ADPMAN subsystem: Nucleotides R_ADPMAN equation: [c] : adpman + h2o --> amp + (2) h + man1p R_ADPRDP subsystem: Nucleotides R_ADPRDP equation: [c] : adprib + h2o --> amp + (2) h + r5p
is: ENSPTRG00000002294.5
product: 939308
fast: false
product: 939272

939163
stoichiometry: 1.0
species: 893102
type: SpeciesReference

005405
stoichiometry: 1.0
species: 901245
type: SpeciesReference

966587
stoichiometry: 1.0
species: 897443
type: SpeciesReference

877081
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _2,4 dihydroxy nitrophenol_C6H5NO4
type: Species

993355
stoichiometry: 1.0
species: 889334
type: SpeciesReference

909324
stoichiometry: 1.0
species: 891640
type: SpeciesReference

984170
stoichiometry: 2.0
species: 891483
type: SpeciesReference

948772
stoichiometry: 1.0
species: 881041
type: SpeciesReference

956088
stoichiometry: 1.0
species: 903185
type: SpeciesReference

885368
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 5a_C45H64N2O51S5X
type: Species

880873
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Acetylcholine_C7H16NO2
type: Species

925236
stoichiometry: 1.0
species: 902198
type: SpeciesReference

009441
stoichiometry: 3.0
species: 885562
type: SpeciesReference

889082
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)4 (GalNAc)1 (Glc)1 (GlcNAc)2 (LFuc)2 (Cer)1_C84H145N4O50FULLRCO
type: Species

990428
stoichiometry: 1.0
species: 886805
type: SpeciesReference

877734
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

958669
stoichiometry: 1.0
species: 897407
type: SpeciesReference

969950
stoichiometry: 1.0
species: 886480
type: SpeciesReference

903198
reactant: 929796
reversible: true
notes: R_PIter subsystem: Transport, Endoplasmic Reticular R_PIter equation: pi[r] <==> pi[c] R_G6Pter subsystem: Transport, Endoplasmic Reticular R_G6Pter equation: g6p[c] <==> g6p[r]
product: 929832
reactant: 929808
product: 929820
type: Reaction
is: ENSPTRG00000004363.4
fast: false

944123
stoichiometry: 1.0
species: 887946
type: SpeciesReference

977663
stoichiometry: 1.0
species: 892789
type: SpeciesReference

913061
stoichiometry: 4.0
species: 891591
type: SpeciesReference

927272
stoichiometry: 1.0
species: 883470
type: SpeciesReference

001737
stoichiometry: 1.0
species: 894468
type: SpeciesReference

957981
stoichiometry: 5.0
species: 897321
type: SpeciesReference

905885
reactant: 953796
is: ENSPTRG00000015418.4
fast: false
product: 953820
product: 953857
product: 953832
reactant: 953808
notes: R_PROSTGD2t subsystem: Transport, Extracellular R_PROSTGD2t equation: hco3[c] + prostgd2[e] <==> hco3[e] + prostgd2[c] R_PROSTGE2t subsystem: Transport, Extracellular R_PROSTGE2t equation: hco3[c] + prostge2[e] <==> hco3[e] + prostge2[c] R_PROSTGE1t subsystem: Transport, Extracellular R_PROSTGE1t equation: hco3[c] + prostge1[e] <==> hco3[e] + prostge1[c]
type: Reaction
reactant: 953772
reactant: 953784
reversible: true
product: 953845

901959
product: 919933
reactant: 919884
reactant: 919897
reactant: 919872
name: _4-Trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
fast: false
notes: R_BBHOX subsystem: Lysine Metabolism R_BBHOX equation: [c] : 4tmeabutn + akg + o2 --> co2 + crn + succ
is: ENSPTRG00000003453.3
product: 919921
reversible: false
product: 919909
type: Reaction

979570
stoichiometry: 1.0
species: 898816
type: SpeciesReference

010405
stoichiometry: 1.0
species: 898032
type: SpeciesReference

897334
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

990771
stoichiometry: 1.0
species: 903644
type: SpeciesReference

947473
stoichiometry: 1.0
species: 894020
type: SpeciesReference

994733
stoichiometry: 1.0
species: 898515
type: SpeciesReference

902222
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Thiocyanate_CNS
type: Species

892037
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Hexacosanoyl-CoA (n-C26:0CoA)_C47H82N7O17P3S
type: Species

962439
stoichiometry: 1.0
species: 902162
type: SpeciesReference

913713
stoichiometry: 2.0
species: 903403
type: SpeciesReference

928938
stoichiometry: 2.0
species: 899795
type: SpeciesReference

900580
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Putrescine_C4H14N2
type: Species

992583
stoichiometry: 2.0
species: 890155
type: SpeciesReference

992473
stoichiometry: 2.0
species: 889466
type: SpeciesReference

899735
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Propionate (n-C3:0)_C3H5O2
type: Species

983942
stoichiometry: 1.0
species: 884270
type: SpeciesReference

993610
stoichiometry: 1.0
species: 893247
type: SpeciesReference

916971
stoichiometry: 1.0
species: 902992
type: SpeciesReference

899662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Palmitoylcarnitine_C23H45NO4
type: Species

964545
stoichiometry: 1.0
species: 895024
type: SpeciesReference

930568
stoichiometry: 1.0
species: 889466
type: SpeciesReference

876596
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _10-formyltetrahydrofolate-[Glu](7)_C50H57N13O25
type: Species

901803
reactant: 918193
product: 918229
reactant: 918181
is: ENSPTRG00000012043.4
notes: R_ACGAMK subsystem: Aminosugar Metabolism R_ACGAMK equation: [c] : acgam + atp --> acgam6p + adp + h R_AMANK subsystem: Aminosugar Metabolism R_AMANK equation: [c] : acmana + atp --> acmanap + adp + h
reactant: 918205
is: http://identifiers.org/ec-code/2.7.1.60
fast: false
product: 918241
reversible: false
product: 918217
product: 918253
type: Reaction
is: http://identifiers.org/ec-code/2.7.1.59

910870
product: 997196
reactant: 997124
product: 997184
reactant: 997136
product: 997208
product: 997172
is: ENSPTRG00000011484.4
is: ENSPTRG00000006470.3
is: ENSPTRG00000020268.4
reversible: true
product: 997160
fast: false
reactant: 997112
type: Reaction
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH3a subsystem: Vitamin A Metabolism R_RDH3a equation: [c] : nadp + retinol-cis-11 <==> h + nadph + retinal-11-cis R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal
is: http://identifiers.org/ec-code/1.1.1.105
reactant: 997148
is: ENSPTRG00000006469.4

909909
notes: R_FUMAC subsystem: Tyrosine metabolism R_FUMAC equation: [c] : 4fumacac + h2o --> acac + fum + h
is: ENSPTRG00000007362.3
reactant: 991015
product: 991039
reversible: false
product: 991051
type: Reaction
name: fumarylacetoacetase
is: http://identifiers.org/ec-code/3.7.1.2
fast: false
reactant: 991027
product: 991063

996388
stoichiometry: 1.0
species: 891591
type: SpeciesReference

897684
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Ammonium_H4N
type: Species

995256
stoichiometry: 1.0
species: 895556
type: SpeciesReference

934208
stoichiometry: 1.0
species: 900304
type: SpeciesReference

975220
stoichiometry: 1.0
species: 899530
type: SpeciesReference

929335
stoichiometry: 16.0
species: 890167
type: SpeciesReference

007689
stoichiometry: 5.0
species: 882817
type: SpeciesReference

902655
product: 926043
product: 926007
product: 925995
product: 926151
product: 926055
product: 926019
product: 926115
reactant: 925983
reactant: 925825
product: 926163
reactant: 925728
reactant: 925753
reactant: 925849
is: ENSPTRG00000020293.3
reactant: 925740
notes: R_GGH_DASH_7DHFl subsystem: Folate Metabolism R_GGH_DASH_7DHFl equation: [l] : 7dhf + h2o --> 6dhf + glu-L R_GGH_DASH_6DHFe subsystem: Folate Metabolism R_GGH_DASH_6DHFe equation: [e] : 6dhf + h2o --> 5dhf + glu-L R_GGH_DASH_6DHFl subsystem: Folate Metabolism R_GGH_DASH_6DHFl equation: [l] : 6dhf + h2o --> 5dhf + glu-L R_GGH_DASH_7THFe subsystem: Folate Metabolism R_GGH_DASH_7THFe equation: [e] : 7thf + h2o --> 6thf + glu-L R_GGH_DASH_7DHFe subsystem: Folate Metabolism R_GGH_DASH_7DHFe equation: [e] : 7dhf + h2o --> 6dhf + glu-L R_GGH_DASH_5THFl subsystem: Folate Metabolism R_GGH_DASH_5THFl equation: [l] : 5thf + (4) h2o --> (4) glu-L + thf R_GGH_DASH_10FTHF5GLUl subsystem: Folate Metabolism R_GGH_DASH_10FTHF5GLUl equation: [l] : 10fthf5glu + (4) h2o --> 10fthf + (4) glu-L R_GGH_DASH_5DHFl subsystem: Folate Metabolism R_GGH_DASH_5DHFl equation: [l] : 5dhf + (4) h2o --> dhf + (4) glu-L R_GGH_DASH_5DHFe subsystem: Folate Metabolism R_GGH_DASH_5DHFe equation: [e] : 5dhf + (4) h2o --> dhf + (4) glu-L R_GGH_DASH_10FTHF5GLUe subsystem: Folate Metabolism R_GGH_DASH_10FTHF5GLUe equation: [e] : 10fthf5glu + (4) h2o --> 10fthf + (4) glu-L R_GGH_DASH_10FTHF6GLUe subsystem: Folate Metabolism R_GGH_DASH_10FTHF6GLUe equation: [e] : 10fthf6glu + h2o --> 10fthf5glu + glu-L R_GGH_DASH_7THFl subsystem: Folate Metabolism R_GGH_DASH_7THFl equation: [l] : 7thf + h2o --> 6thf + glu-L R_GGH_DASH_10FTHF7GLUl subsystem: Folate Metabolism R_GGH_DASH_10FTHF7GLUl equation: [l] : 10fthf7glu + h2o --> 10fthf6glu + glu-L R_GGH_DASH_5THFe subsystem: Folate Metabolism R_GGH_DASH_5THFe equation: [e] : 5thf + (4) h2o --> (4) glu-L + thf R_GGH_DASH_10FTHF6GLUl subsystem: Folate Metabolism R_GGH_DASH_10FTHF6GLUl equation: [l] : 10fthf6glu + h2o --> 10fthf5glu + glu-L R_GGH_DASH_6THFl subsystem: Folate Metabolism R_GGH_DASH_6THFl equation: [l] : 6thf + h2o --> 5thf + glu-L R_M14NTg subsystem: N-Glycan Biosynthesis R_M14NTg equation: [g] : n2m2masn + uacgam --> h + n2m2nmasn + udp R_GGH_DASH_6THFe subsys…
reversible: false
product: 926091
reactant: 925959
reactant: 925923
reactant: 925874
is: http://identifiers.org/ec-code/2.4.1.144
reactant: 925971
product: 926127
product: 926103
product: 926175
product: 926139
type: Reaction
product: 926187
reactant: 925777
fast: false
reactant: 925813
product: 926067
product: 926247
product: 926079
reactant: 925837
reactant: 925947
product: 926031
reactant: 925801
product: 926211
product: 926223
product: 926259
reactant: 925765
reactant: 925911
reactant: 925862
product: 926235
product: 926199
reactant: 925789
reactant: 925935
reactant: 925886
reactant: 925899

009597
stoichiometry: 1.0
species: 883868
type: SpeciesReference

965222
stoichiometry: 1.0
species: 899530
type: SpeciesReference

965913
stoichiometry: 1.0
species: 901801
type: SpeciesReference

991099
stoichiometry: 1.0
species: 893090
type: SpeciesReference

951899
stoichiometry: 1.0
species: 888502
type: SpeciesReference

913602
stoichiometry: 17.0
species: 897261
type: SpeciesReference

986326
stoichiometry: 1.0
species: 878000
type: SpeciesReference

990111
stoichiometry: 1.0
species: 894224
type: SpeciesReference

008803
stoichiometry: 2.0
species: 900751
type: SpeciesReference

877191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _2-Decaprenyl-6-methoxyphenol_C57H88O2
type: Species

948844
stoichiometry: 1.0
species: 894395
type: SpeciesReference

971815
stoichiometry: 1.0
species: 894080
type: SpeciesReference

900885
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cis-9-retinal_C20H28O
type: Species

995405
stoichiometry: 111.0
species: 884427
type: SpeciesReference

945508
stoichiometry: 1.0
species: 886733
type: SpeciesReference

908804
is: http://identifiers.org/ec-code/3.5.3.1
reactant: 981119
reactant: 981167
product: 981179
fast: false
notes: R_AKR1C1 subsystem: Steroid Metabolism R_AKR1C1 equation: [c] : h + nadph + prgstrn --> aprgstrn + nadp R_ARGNm subsystem: Urea cycle/amino group metabolism R_ARGNm equation: [m] : arg-L + h2o --> orn + urea
reversible: false
is: ENSPTRG00000002248.5
type: Reaction
is: ENSPTRG00000032653.1
product: 981215
reactant: 981155
product: 981203
is: ENSPTRG00000023281.3
reactant: 981143
product: 981191
reactant: 981131

902656
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO
type: Species

006019
stoichiometry: 2.0
species: 891664
type: SpeciesReference

988361
stoichiometry: 1.0
species: 891604
type: SpeciesReference

926500
stoichiometry: 1.0
species: 880183
type: SpeciesReference

981491
stoichiometry: 1.0
species: 884210
type: SpeciesReference

901052
is: http://identifiers.org/ec-code/2.3.1.7
fast: false
product: 913834
is: ENSPTRG00000019367.3
product: 913822
reactant: 913810
reversible: true
reactant: 913798
type: Reaction
name: carnitine dimethyl nonanoyl transferase, revsible, peroxisomal
notes: R_CSNAT2x subsystem: Fatty Acid Metabolism R_CSNAT2x equation: [x] : crn + dmnoncoa <==> coa + dmnoncrn

981772
stoichiometry: 1.0
species: 900739
type: SpeciesReference

979799
stoichiometry: 1.0
species: 902680
type: SpeciesReference

965051
stoichiometry: 1.0
species: 877468
type: SpeciesReference

932573
stoichiometry: 1.0
species: 887107
type: SpeciesReference

885477
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate E (GalNAc4,6diS-GlcA) proteoglycan_C45H63N2O54S6X
type: Species

904140
product: 937424
is: ENSPTRG00000000705.3
reversible: false
reactant: 937400
product: 937436
type: Reaction
product: 937461
reactant: 937388
product: 937412
fast: false
notes: R_FAH3 subsystem: CYP Metabolism R_FAH3 equation: [c] : h + hdca + nadph + o2 --> h2o + nadp + whhdca R_FAH1 subsystem: CYP Metabolism R_FAH1 equation: [c] : ddca + h + nadph + o2 --> h2o + nadp + whddca R_FAH2 subsystem: CYP Metabolism R_FAH2 equation: [c] : h + nadph + o2 + ttdca --> h2o + nadp + whttdca
reactant: 937376
product: 937449
reactant: 937352
reactant: 937364
reactant: 937340

009043
stoichiometry: 1.0
species: 876837
type: SpeciesReference

939272
stoichiometry: 1.0
species: 900824
type: SpeciesReference

919655
stoichiometry: 1.0
species: 889778
type: SpeciesReference

912650
stoichiometry: 1.0
species: 894963
type: SpeciesReference

967532
stoichiometry: 1.0
species: 886492
type: SpeciesReference

001629
stoichiometry: 1.0
species: 893695
type: SpeciesReference

888309
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Fructose 1-phosphate_C6H11O9P
type: Species

908801
stoichiometry: 3.0
species: 884427
type: SpeciesReference

901801
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Serotonin_C10H13N2O
type: Species

979871
stoichiometry: 1.0
species: 891616
type: SpeciesReference

986879
stoichiometry: 2.0
species: 891664
type: SpeciesReference

894395
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 7_C115H187N8O85SX
type: Species

919197
stoichiometry: 1.0
species: 901549
type: SpeciesReference

994177
stoichiometry: 1.0
species: 901549
type: SpeciesReference

907027
stoichiometry: 1.0
species: 888188
type: SpeciesReference

985962
stoichiometry: 2.0
species: 891567
type: SpeciesReference

915585
stoichiometry: 25.0
species: 891591
type: SpeciesReference

951671
stoichiometry: 1.0
species: 901195
type: SpeciesReference

898600
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Oxalate_C2O4
type: Species

971755
stoichiometry: 1.0
species: 897696
type: SpeciesReference

010514
stoichiometry: 3.0
species: 897431
type: SpeciesReference

929576
stoichiometry: 2.0
species: 891640
type: SpeciesReference

974147
stoichiometry: 1.0
species: 903970
type: SpeciesReference

940079
stoichiometry: 5.0
species: 897347
type: SpeciesReference

944014
stoichiometry: 1.0
species: 890338
type: SpeciesReference

969841
stoichiometry: 1.0
species: 904127
type: SpeciesReference

958778
stoichiometry: 2.0
species: 897419
type: SpeciesReference

976149
stoichiometry: 2.0
species: 882030
type: SpeciesReference

995142
stoichiometry: 1.0
species: 891905
type: SpeciesReference

878835
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _5alpha-Dihydrotestosterone glucuronide_C25H38O8
type: Species

977554
stoichiometry: 1.0
species: 892741
type: SpeciesReference

961041
stoichiometry: 1.0
species: 903452
type: SpeciesReference

980246
stoichiometry: 1.0
species: 890034
type: SpeciesReference

905006
stoichiometry: 1.0
species: 900111
type: SpeciesReference

901054
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: PA6_C90H145N6O65X
type: Species

877360
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _2-Oxobutanoate_C4H5O3
type: Species

007205
stoichiometry: 6.0
species: 897273
type: SpeciesReference

946750
stoichiometry: 1.0
species: 897443
type: SpeciesReference

979137
stoichiometry: 1.0
species: 889766
type: SpeciesReference

985637
stoichiometry: 1.0
species: 889322
type: SpeciesReference

886997
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _2,6 dimethylheptanoyl-CoA_C30H52N7O17P3S
type: Species

885647
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Cytidine_C9H13N3O5
type: Species

884958
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), free chain_C45H66N2O49S4
type: Species

958381
stoichiometry: 4.0
species: 897273
type: SpeciesReference

985816
stoichiometry: 1.0
species: 884693
type: SpeciesReference

940938
stoichiometry: 1.0
species: 900703
type: SpeciesReference

911902
stoichiometry: 1.0
species: 891616
type: SpeciesReference

952491
stoichiometry: 2.0
species: 896704
type: SpeciesReference

002013
stoichiometry: 1.0
species: 891591
type: SpeciesReference

909905
stoichiometry: 1.0
species: 882781
type: SpeciesReference

915295
stoichiometry: 1.0
species: 895024
type: SpeciesReference

988929
stoichiometry: 2.0
species: 891652
type: SpeciesReference

948207
stoichiometry: 1.0
species: 891929
type: SpeciesReference

892765
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: heparan sulfate, precursor 5_C59H89N3O47X
type: Species

890143
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: D-glucurono-6,3-lactone_C6H8O6
type: Species

916212
stoichiometry: 1.0
species: 897912
type: SpeciesReference

000024
stoichiometry: 2.0
species: 891266
type: SpeciesReference

902114
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2
type: Species

904356
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _7alpha-Hydroxycholest-4-en-3-one_C27H44O2
type: Species

954568
stoichiometry: 2.0
species: 890362
type: SpeciesReference

904357
is: ENSPTRG00000014550.4
product: 939763
product: 939751
reactant: 939715
product: 939739
type: Reaction
reactant: 939727
fast: false
reversible: false
is: http://identifiers.org/ec-code/3.1.6.8
notes: R_ARSA subsystem: Sphingolipid Metabolism R_ARSA equation: [l] : h2o + sgalside_hs --> galside_hs + h + so4
name: Arylsulfatase A

964388
stoichiometry: 1.0
species: 893321
type: SpeciesReference

931898
stoichiometry: 2.0
species: 881258
type: SpeciesReference

921929
stoichiometry: 1.0
species: 882781
type: SpeciesReference

917139
stoichiometry: 1.0
species: 884133
type: SpeciesReference

895653
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: gamma-linolenyl carnitine_C25H43NO4
type: Species

906507
stoichiometry: 2.0
species: 881258
type: SpeciesReference

963139
stoichiometry: 2.0
species: 891447
type: SpeciesReference

884097
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cardiolipin (homo sapiens)_C9H16O9P2FULLRCO2FULLR2CO2FULLRCO2FULLR2CO2
type: Species

936340
stoichiometry: 1.0
species: 884983
type: SpeciesReference

967194
stoichiometry: 1.0
species: 899299
type: SpeciesReference

951259
stoichiometry: 1.0
species: 901426
type: SpeciesReference

933781
stoichiometry: 1.0
species: 899530
type: SpeciesReference

925128
stoichiometry: 1.0
species: 891591
type: SpeciesReference

952636
stoichiometry: 1.0
species: 888502
type: SpeciesReference

907762
reactant: 969853
reactant: 969779
product: 970022
reactant: 969828
reactant: 969816
fast: false
reactant: 969792
reactant: 969841
reactant: 969767
product: 969986
product: 969974
reactant: 969804
product: 969901
reversible: false
reactant: 969742
reactant: 969754
product: 969950
product: 969913
product: 969889
is: http://identifiers.org/ec-code/1.14.13.15
reactant: 969730
product: 969962
product: 969998
product: 970034
product: 970010
product: 969938
product: 969925
type: Reaction
reactant: 969877
reactant: 969865
notes: R_P45027A11m subsystem: Bile Acid Biosynthesis R_P45027A11m equation: [m] : h + nadph + o2 + xoltriol --> h2o + nadp + xoltetrol R_P45027A16m subsystem: Bile Acid Biosynthesis R_P45027A16m equation: [m] : nadph + o2 + xol7ah2al --> dhcholestanate + h2o + nadp R_VITD3Hm subsystem: Vitamin D R_VITD3Hm equation: [m] : h + nadph + o2 + vitd3 --> 25hvitd3 + h2o + nadp R_P45027A14m subsystem: Bile Acid Biosynthesis R_P45027A14m equation: [m] : h + nadph + o2 + xol7ah2 --> h2o + nadp + xol7ah3 R_P45027A15m subsystem: Bile Acid Biosynthesis R_P45027A15m equation: [m] : h + nadph + o2 + xol7ah3 --> (2) h2o + nadp + xol7ah2al R_P45027A13m subsystem: Bile Acid Biosynthesis R_P45027A13m equation: [m] : nadph + o2 + thcholst --> h2o + nadp + thcholstoic R_P45027A1m subsystem: Bile Acid Biosynthesis R_P45027A1m equation: [m] : chsterol + h + nadph + o2 --> h2o + nadp + xol27oh R_VITD2Hm subsystem: Vitamin D R_VITD2Hm equation: [m] : h + nadph + o2 + vitd2 --> 25hvitd2 + h2o + nadp R_P45027A12m subsystem: Bile Acid Biosynthesis R_P45027A12m equation: [m] : nadp + xoltetrol --> h + nadph + thcholst
is: ENSPTRG00000012928.3

917490
stoichiometry: 1.0
species: 897321
type: SpeciesReference

903706
reactant: 934245
product: 934361
reversible: false
notes: R_LCADim subsystem: Pyruvate Metabolism R_LCADim equation: [m] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDDm subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDDm equation: [m] : gcald + h2o + nad --> glyclt + (2) h + nadh R_SSALxm subsystem: Glutamate metabolism R_SSALxm equation: [m] : h2o + nad + sucsal --> (2) h + nadh + succ R_LCADi_Dm subsystem: Pyruvate Metabolism R_LCADi_Dm equation: [m] : h2o + lald-D + nad --> (2) h + lac-D + nadh
product: 934309
reactant: 934270
reactant: 934283
product: 934323
type: Reaction
reactant: 934233
is: http://identifiers.org/ec-code/1.2.1.24
is: ENSPTRG00000017776.5
reactant: 934257
product: 934336
is: http://identifiers.org/ec-code/1.2.1.21
product: 934373
product: 934349
reactant: 934296
fast: false

970697
stoichiometry: 1.0
species: 877926
type: SpeciesReference

876488
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

898212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: _9-O-Acetylated GD3 (homo sapiens)_C54H90N3O29FULLRCO
type: Species

902115
reactant: 921519
reactant: 921543
reversible: true
reactant: 921446
type: Reaction
product: 921591
reactant: 921531
product: 921603
reactant: 921434
notes: R_DALAt2r subsystem: Transport, Extracellular R_DALAt2r equation: ala-D[e] + h[e] <==> ala-D[c] + h[c] R_ALAt2rL subsystem: Transport, Lysosomal R_ALAt2rL equation: ala-L[l] + h[l] <==> ala-L[c] + h[c] R_DALAt2rL subsystem: Transport, Lysosomal R_DALAt2rL equation: ala-D[l] + h[l] <==> ala-D[c] + h[c] R_ABUTt2r subsystem: Transport, Extracellular R_ABUTt2r equation: _4abut[e] + h[e] <==> 4abut[c] + h[c] R_PROt2r subsystem: Transport, Extracellular R_PROt2r equation: h[e] + pro-L[e] <==> h[c] + pro-L[c] R_ALAt2r subsystem: Transport, Extracellular R_ALAt2r equation: ala-L[e] + h[e] <==> ala-L[c] + h[c] R_GLYt2r subsystem: Transport, Extracellular R_GLYt2r equation: gly[e] + h[e] <==> gly[c] + h[c] R_PRODt2rL subsystem: Transport, Lysosomal R_PRODt2rL equation: h[l] + pro-D[l] <==> h[c] + pro-D[c] R_PROt2rL subsystem: Transport, Lysosomal R_PROt2rL equation: h[l] + pro-L[l] <==> h[c] + pro-L[c] R_PRODt2r subsystem: Transport, Extracellular R_PRODt2r equation: h[e] + pro-D[e] <==> h[c] + pro-D[c] R_ABUTt2rL subsystem: Transport, Lysosomal R_ABUTt2rL equation: _4abut[l] + h[l] <==> 4abut[c] + h[c] R_GLYt2rL subsystem: Transport, Lysosomal R_GLYt2rL equation: gly[l] + h[l] <==> gly[c] + h[c]
product: 921663
reactant: 921422
product: 921639
reactant: 921494
product: 921627
is: ENSPTRG00000017434.2
reactant: 921458
reactant: 921482
reactant: 921579
product: 921651
product: 921615
reactant: 921567
reactant: 921470
fast: false
reactant: 921506
reactant: 921555

997400
stoichiometry: 1.0
species: 886612
type: SpeciesReference

966431
stoichiometry: 3.0
species: 899578
type: SpeciesReference

999440
stoichiometry: 1.0
species: 883179
type: SpeciesReference

911042
stoichiometry: 1.0
species: 901281
type: SpeciesReference

968605
stoichiometry: 1.0
species: 892220
type: SpeciesReference

880015
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: R total_CO2FULLR
type: Species

939968
stoichiometry: 1.0
species: 884319
type: SpeciesReference

989085
stoichiometry: 1.0
species: 880317
type: SpeciesReference

000350
stoichiometry: 1.0
species: 876500
type: SpeciesReference

931330
stoichiometry: 1.0
species: 881463
type: SpeciesReference

881547
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Agmatine_C5H16N4
type: Species

911267
product: 001629
reactant: 001497
product: 001677
product: 001737
notes: R_S6TASE23ly subsystem: Keratan sulfate degradation R_S6TASE23ly equation: [l] : h2o + ksii_core2_deg3 <==> h + ksii_core2_deg4 + so4 R_S6TASE15ly subsystem: Keratan sulfate degradation R_S6TASE15ly equation: [l] : h2o + ksi_deg18 <==> h + ksi_deg19 + so4 R_S6TASE13ly subsystem: Keratan sulfate degradation R_S6TASE13ly equation: [l] : h2o + ksi_deg12 <==> h + ksi_deg13 + so4 R_S6TASE26ly subsystem: Keratan sulfate degradation R_S6TASE26ly equation: [l] : h2o + ksii_core4_deg3 <==> h + ksii_core4_deg4 + so4 R_S6TASE12ly subsystem: Keratan sulfate degradation R_S6TASE12ly equation: [l] : h2o + ksi_deg9 <==> h + ksi_deg10 + so4 R_S6TASE20ly subsystem: Keratan sulfate degradation R_S6TASE20ly equation: [l] : h2o + ksi_deg33 <==> h + ksi_deg34 + so4 R_S6TASE17ly subsystem: Keratan sulfate degradation R_S6TASE17ly equation: [l] : h2o + ksi_deg24 <==> h + ksi_deg25 + so4 R_S6TASE21ly subsystem: Keratan sulfate degradation R_S6TASE21ly equation: [l] : h2o + ksi_deg36 <==> h + ksi_deg37 + so4 R_S6TASE11ly subsystem: Keratan sulfate degradation R_S6TASE11ly equation: [l] : h2o + ksi_deg6 <==> h + ksi_deg7 + so4 R_S6TASE3ly subsystem: Heparan sulfate degradation R_S6TASE3ly equation: [l] : h2o + hs_deg11 <==> h + hs_deg12 + so4 R_S6TASE1ly subsystem: Heparan sulfate degradation R_S6TASE1ly equation: [l] : h2o + hs <==> h + hs_deg1 + so4 R_S6TASE24ly subsystem: Keratan sulfate degradation R_S6TASE24ly equation: [l] : h2o + ksii_core2_deg6 <==> h + ksii_core2_deg7 + so4 R_S6TASE2ly subsystem: Heparan sulfate degradation R_S6TASE2ly equation: [l] : h2o + hs_deg5 <==> h + hs_deg6 + so4 R_S6TASE16ly subsystem: Keratan sulfate degradation R_S6TASE16ly equation: [l] : h2o + ksi_deg21 <==> h + ksi_deg22 + so4 R_S6TASE14ly subsystem: Keratan sulfate degradation R_S6TASE14ly equation: [l] : h2o + ksi_deg15 <==> h + ksi_deg16 + so4 R_S6TASE19ly subsystem: Keratan sulfate degradation R_S6TASE19ly equation: [l] : h2o + ksi_deg30 <==> h + ksi_deg31 + so4 R_S6TASE18ly subsystem: Keratan sulf…
reactant: 001425
reactant: 001461
reactant: 001437
is: http://identifiers.org/ec-code/3.1.6.14
product: 001617
reactant: 001473
product: 001821
reversible: true
reactant: 001521
reactant: 001533
product: 001725
product: 001701
reactant: 001545
reactant: 001581
product: 001773
reactant: 001593
product: 001665
product: 001809
reactant: 001449
fast: false
product: 001605
product: 001653
reactant: 001557
product: 001761
product: 001749
reactant: 001569
product: 001713
reactant: 001401
type: Reaction
product: 001689
reactant: 001413
reactant: 001509
reactant: 001389
product: 001797
is: ENSPTRG00000005176.3
product: 001641
product: 001785
reactant: 001485

905733
stoichiometry: 1.0
species: 891483
type: SpeciesReference

972795
stoichiometry: 1.0
species: 894747
type: SpeciesReference

931740
stoichiometry: 3.0
species: 882054
type: SpeciesReference

922061
stoichiometry: 1.0
species: 891640
type: SpeciesReference

994455
stoichiometry: 1.0
species: 895919
type: SpeciesReference

930098
stoichiometry: 2.0
species: 881764
type: SpeciesReference

917817
stoichiometry: 1.0
species: 880389
type: SpeciesReference

985063
stoichiometry: 1.0
species: 903644
type: SpeciesReference

920285
stoichiometry: 1.0
species: 894759
type: SpeciesReference

978061
stoichiometry: 1.0
species: 895423
type: SpeciesReference

907761
stoichiometry: 32.0
species: 891676
type: SpeciesReference

907317
is: http://identifiers.org/ec-code/1.4.3.6
reactant: 964961
product: 965051
product: 965037
product: 965210
reactant: 964985
reactant: 964826
reactant: 964862
product: 965024
reactant: 964910
product: 965125
notes: R_3MOXTYROX subsystem: Tyrosine metabolism R_3MOXTYROX equation: [c] : 3moxtyr + h2o + o2 --> 3mox4hpac + h2o2 + nh4 R_MAOLNOR subsystem: Tyrosine metabolism R_MAOLNOR equation: [c] : h2o + normete-L + o2 --> 3m4hpga + h2o2 + nh4 R_APRTO2 subsystem: Arginine and Proline Metabolism R_APRTO2 equation: [c] : aprut + h2o + o2 --> h2o2 + n4abutn + nh4 R_42A12BOOX subsystem: Tyrosine metabolism R_42A12BOOX equation: [c] : dopa + h2o + o2 --> 34dhpac + h2o2 + nh4 R_PEAMNO subsystem: Phenylalanine metabolism R_PEAMNO equation: [c] : h2o + o2 + peamn --> h2o2 + nh4 + pacald R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_3HXKYNOXDA subsystem: Tryptophan metabolism R_3HXKYNOXDA equation: [c] : 3hxkynam + o2 --> 48dhoxquin + h2o2 + nh4 R_41R2A1H12BOOX subsystem: Tyrosine metabolism R_41R2A1H12BOOX equation: [c] : h2o + nrpphr + o2 --> 34dhmald + h2o2 + nh4 R_TRYPTAOX subsystem: Tryptophan metabolism R_TRYPTAOX equation: [c] : h2o + o2 + trypta --> h2o2 + id3acald + nh4 R_5HXKYNOXDA subsystem: Tryptophan metabolism R_5HXKYNOXDA equation: [c] : 5hxkynam + o2 --> 46dhoxquin + h2o2 + nh4 R_TYROXDAc subsystem: Tyrosine metabolism R_TYROXDAc equation: [c] : h2o + o2 + tym --> 4hoxpacd + h2o2 + nh4 R_5HOXINOXDA subsystem: Tryptophan metabolism R_5HOXINOXDA equation: [c] : h2o + o2 + srtn --> 5hoxindact + h2o2 + nh4 R_41R1H2MAE12BOOX subsystem: Tyrosine metabolism R_41R1H2MAE12BOOX equation: [c] : adrnl + h2o + o2 --> 34dhmald + h2o2 + mma
product: 965174
product: 965137
reactant: 964886
reactant: 964948
product: 965064
type: Reaction
reactant: 964814
product: 965198
is: http://identifiers.org/ec-code/1.2.1.5
reactant: 964850
reactant: 964973
product: 965186
product: 965149
fast: false
reactant: 964935
reactant: 964898
product: 965077
is: http://identifiers.org/ec-code/1.4.3.4
product: 965089
reactant: 964838
product: 965101
is: ENSPTRG00000021817.4
product: 965161
reactant: 964874
product: 965113
reactant: 964922
product: 965011
reactant: 964998
reversible: false

941588
stoichiometry: 1.0
species: 887437
type: SpeciesReference

999952
stoichiometry: 3.0
species: 897273
type: SpeciesReference

987687
stoichiometry: 1.0
species: 886708
type: SpeciesReference

936676
stoichiometry: 1.0
species: 901342
type: SpeciesReference

939895
stoichiometry: 1.0
species: 886203
type: SpeciesReference

881125
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: O-Acetylcarnitine_C9H17NO4
type: Species

894056
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 15_C149H240N10O119S4X
type: Species

950797
stoichiometry: 1.0
species: 901426
type: SpeciesReference

894663
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate II biosynthesis, precursor 8_C75H121N6O56SX
type: Species

003992
stoichiometry: 2.0
species: 893707
type: SpeciesReference

943607
stoichiometry: 1.0
species: 897552
type: SpeciesReference

964998
stoichiometry: 1.0
species: 882372
type: SpeciesReference

895544
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: alpha-Linolenoyl-CoA_C39H60N7O17P3S
type: Species

901162
is: http://identifiers.org/ec-code/3.2.1.96
notes: R_ENGASE2 subsystem: N-Glycan Degradation R_ENGASE2 equation: [c] : h2o + n2m2nm --> acgam + n2m2nmn R_ENGASE subsystem: N-Glycan Degradation R_ENGASE equation: [c] : h2o + s2l2n2m2m --> acgam + s2l2n2m2mn
product: 914486
reactant: 914474
reversible: false
fast: false
product: 914510
reactant: 914462
is: ENSPTRG00000009725.5
reactant: 914450
product: 914498
type: Reaction

942716
stoichiometry: 35.0
species: 897431
type: SpeciesReference

957282
stoichiometry: 1.0
species: 884000
type: SpeciesReference

989870
stoichiometry: 1.0
species: 894651
type: SpeciesReference

883711
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Choline_C5H14NO
type: Species

879523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: heptaglutamyl folate (THF)_C49H57N13O24
type: Species

943692
stoichiometry: 1.0
species: 897395
type: SpeciesReference

941179
stoichiometry: 1.0
species: 891555
type: SpeciesReference

936267
stoichiometry: 1.0
species: 897492
type: SpeciesReference

911903
is: ENSPTRG00000005378.4
type: Reaction
product: 008863
product: 008827
reversible: false
notes: R_TRDR subsystem: Nucleotides R_TRDR equation: [c] : h + nadph + trdox --> nadp + trdrd R_TRDR2 subsystem: Miscellaneous R_TRDR2 equation: [c] : h + nadph + q10 --> nadp + q10h2 R_TRDR3 subsystem: Miscellaneous R_TRDR3 equation: [c] : h + nadh + q10 --> nad + q10h2
fast: false
reactant: 008779
product: 008851
reactant: 008815
reactant: 008767
reactant: 008803
reactant: 008791
product: 008839
is: http://identifiers.org/ec-code/1.8.1.9

962958
stoichiometry: 1.0
species: 889490
type: SpeciesReference

004389
stoichiometry: 1.0
species: 885200
type: SpeciesReference

903704
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: UDP-D-xylose_C14H20N2O16P2
type: Species

938016
stoichiometry: 1.0
species: 882493
type: SpeciesReference

918265
stoichiometry: 1.0
species: 880256
type: SpeciesReference

892873
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Hypoxanthine_C5H4N4O
type: Species

967678
stoichiometry: 2.0
species: 882829
type: SpeciesReference

920406
stoichiometry: 1.0
species: 885452
type: SpeciesReference

900883
is: ENSPTRG00000008389.3
name: beta-Carotene dioxygenase
fast: false
reactant: 911926
reversible: false
type: Reaction
reactant: 911938
product: 911950
notes: R_BCDO subsystem: Vitamin A Metabolism R_BCDO equation: [c] : caro + o2 --> (2) retinal
is: http://identifiers.org/ec-code/1.14.99.36

921205
stoichiometry: 1.0
species: 887033
type: SpeciesReference

987109
stoichiometry: 2.0
species: 899238
type: SpeciesReference

944581
stoichiometry: 2.0
species: 896016
type: SpeciesReference

983096
stoichiometry: 1.0
species: 891591
type: SpeciesReference

929796
stoichiometry: 1.0
species: 899602
type: SpeciesReference

969401
stoichiometry: 1.0
species: 903524
type: SpeciesReference

976606
stoichiometry: 3.0
species: 882781
type: SpeciesReference

923411
stoichiometry: 1.0
species: 876983
type: SpeciesReference

984736
stoichiometry: 1.0
species: 878956
type: SpeciesReference

988205
stoichiometry: 1.0
species: 885562
type: SpeciesReference

001509
stoichiometry: 1.0
species: 893514
type: SpeciesReference

930785
stoichiometry: 1.0
species: 895737
type: SpeciesReference

899518
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: phytanyl coa_C41H70N7O17P3S
type: Species

877020
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1-Pyrroline-5-carboxylate_C5H6NO2
type: Species

880171
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: trans-4-Hydroxycinnamate_C9H7O3
type: Species

890806
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GM1alpha (homo sapiens)_C55H95N3O30FULLRCO
type: Species

940500
stoichiometry: 1.0
species: 877360
type: SpeciesReference

008099
stoichiometry: 1.0
species: 882805
type: SpeciesReference

905512
reversible: true
fast: false
product: 950822
reactant: 950810
name: Phosphatidylserine synthase homo sapiens
notes: R_PSSA1_hs subsystem: Glycerophospholipid Metabolism R_PSSA1_hs equation: [c] : pchol_hs + ser-L <==> chol + ps_hs
reactant: 950797
type: Reaction
is: http://identifiers.org/ec-code/2.7.8.8
product: 950834
is: ENSPTRG00000020442.3

944436
stoichiometry: 1.0
species: 895992
type: SpeciesReference

950701
stoichiometry: 5.0
species: 886287
type: SpeciesReference

907327
stoichiometry: 1.0
species: 885200
type: SpeciesReference

934135
stoichiometry: 1.0
species: 903596
type: SpeciesReference

887144
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Dolichol diphosphate, human liver homolog_C1080H1758O70P20
type: Species

947327
stoichiometry: 1.0
species: 883227
type: SpeciesReference

910307
stoichiometry: 3.0
species: 881258
type: SpeciesReference

907591
stoichiometry: 1.0
species: 895629
type: SpeciesReference

001845
stoichiometry: 1.0
species: 895061
type: SpeciesReference

908417
type: Reaction
reactant: 977397
reactant: 977409
product: 977446
notes: R_GALK subsystem: Galactose metabolism R_GALK equation: [c] : atp + gal --> adp + gal1p + h
is: http://identifiers.org/ec-code/2.7.1.6
product: 977421
is: ENSPTRG00000009654.3
is: ENSPTRG00000007052.4
product: 977433
name: galactokinase
fast: false
reversible: false

926464
stoichiometry: 1.0
species: 891640
type: SpeciesReference

912856
stoichiometry: 1.0
species: 900050
type: SpeciesReference

893562
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 19_C146H236N10O124S6
type: Species

990317
stoichiometry: 1.0
species: 890806
type: SpeciesReference

995987
stoichiometry: 2.0
species: 899904
type: SpeciesReference

891965
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: trans-Hexadec-2-enoyl carnitine_C23H43NO4
type: Species

942933
stoichiometry: 1.0
species: 885864
type: SpeciesReference

938921
stoichiometry: 1.0
species: 891254
type: SpeciesReference

958925
stoichiometry: 2.0
species: 891616
type: SpeciesReference

899880
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Diphosphoinositol tetrakisphosphate_C6H7O24P6
type: Species

958066
stoichiometry: 5.0
species: 891591
type: SpeciesReference

928480
stoichiometry: 2.0
species: 889526
type: SpeciesReference

970022
stoichiometry: 1.0
species: 897528
type: SpeciesReference

895138
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: L-Leucine_C6H13NO2
type: Species

934613
stoichiometry: 1.0
species: 888418
type: SpeciesReference

896511
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: (mannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (B)_C45H84N2O27P2FULLRCO2FULLR2CO2
type: Species

943065
stoichiometry: 1.0
species: 887363
type: SpeciesReference

986168
stoichiometry: 2.0
species: 898708
type: SpeciesReference

927840
stoichiometry: 2.0
species: 897480
type: SpeciesReference

888526
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Fe2+_Fe
type: Species

998297
stoichiometry: 1.0
species: 894795
type: SpeciesReference

910978
product: 998224
product: 998212
reactant: 998176
name: pyruvate carboxylase
is: ENSPTRG00000023133.2
reactant: 998164
product: 998200
notes: R_PCm subsystem: Pyruvate Metabolism R_PCm equation: [m] : atp + hco3 + pyr --> adp + h + oaa + pi
fast: false
type: Reaction
reactant: 998188
reversible: false
product: 998236
is: http://identifiers.org/ec-code/6.4.1.1

925344
stoichiometry: 1.0
species: 900703
type: SpeciesReference

977772
stoichiometry: 1.0
species: 901910
type: SpeciesReference

971323
stoichiometry: 1.0
species: 890698
type: SpeciesReference

962548
stoichiometry: 2.0
species: 891495
type: SpeciesReference

973615
stoichiometry: 1.0
species: 896100
type: SpeciesReference

001221
stoichiometry: 1.0
species: 901801
type: SpeciesReference

929118
stoichiometry: 1.0
species: 902114
type: SpeciesReference

992256
stoichiometry: 2.0
species: 903656
type: SpeciesReference

912433
stoichiometry: 1.0
species: 884121
type: SpeciesReference

902331
product: 923618
product: 923654
reactant: 923582
notes: R_CTPS2 subsystem: Pyrimidine Biosynthesis R_CTPS2 equation: [c] : atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi
is: ENSPTRG00000021698.4
reactant: 923557
product: 923630
reactant: 923594
name: CTP synthase (glutamine)
type: Reaction
reversible: false
fast: false
product: 923606
product: 923642
is: http://identifiers.org/ec-code/6.3.4.2
reactant: 923569

957547
stoichiometry: 2.0
species: 898696
type: SpeciesReference

915367
stoichiometry: 1.0
species: 900678
type: SpeciesReference

908288
stoichiometry: 1.0
species: 876898
type: SpeciesReference

907593
fast: false
product: 968160
product: 968148
notes: R_AKR1D2 subsystem: Bile Acid Biosynthesis R_AKR1D2 equation: [c] : h + nadph + xoldiolone --> nadp + xoldioloneh R_AKR1D subsystem: Bile Acid Biosynthesis R_AKR1D equation: [c] : h + nadph + xol7aone --> nadp + xol7ah
type: Reaction
is: ENSPTRG00000004572.3
product: 968172
reactant: 968124
reversible: false
reactant: 968100
reactant: 968136
reactant: 968112

994019
stoichiometry: 4.0
species: 891519
type: SpeciesReference

949292
stoichiometry: 1.0
species: 888659
type: SpeciesReference

975678
stoichiometry: 1.0
species: 878703
type: SpeciesReference

906247
is: ENSPTRG00000001094.5
reactant: 957282
reversible: false
notes: R_CHTNASEe subsystem: Aminosugar Metabolism R_CHTNASEe equation: [e] : chtn + (2) h2o --> (3) acgam R_CHTNASE subsystem: Aminosugar Metabolism R_CHTNASE equation: [c] : chtn + (2) h2o --> (3) acgam
product: 957306
product: 957294
fast: false
reactant: 957246
type: Reaction
is: ENSPTRG00000030438.2
reactant: 957258
reactant: 957270
is: http://identifiers.org/ec-code/3.2.1.14

908419
stoichiometry: 1.0
species: 889754
type: SpeciesReference

974425
stoichiometry: 1.0
species: 879017
type: SpeciesReference

998357
stoichiometry: 1.0
species: 894044
type: SpeciesReference

964777
stoichiometry: 1.0
species: 890326
type: SpeciesReference

912759
stoichiometry: 1.0
species: 891447
type: SpeciesReference

953496
stoichiometry: 2.0
species: 898563
type: SpeciesReference

945254
stoichiometry: 2.0
species: 897528
type: SpeciesReference

945688
stoichiometry: 1.0
species: 879691
type: SpeciesReference

926839
stoichiometry: 3.0
species: 897261
type: SpeciesReference

971974
stoichiometry: 1.0
species: 894322
type: SpeciesReference

902330
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S
type: Species

908287
name: Carboxylesterase (cocaine) (er)
reversible: false
product: 976125
fast: false
type: Reaction
reactant: 976101
is: ENSPTRG00000008209.2
is: http://identifiers.org/ec-code/3.1.1.1
product: 976137
product: 976113
notes: R_COKECBESr subsystem: Alkaloid biosynthesis II R_COKECBESr equation: [r] : coke + h2o --> bz + egme + h
reactant: 976089

948426
stoichiometry: 2.0
species: 901922
type: SpeciesReference

880728
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Acetyl-D-glucosamine 6-phosphate_C8H14NO9P
type: Species

905661
stoichiometry: 1.0
species: 903088
type: SpeciesReference

993947
stoichiometry: 1.0
species: 890494
type: SpeciesReference

951150
stoichiometry: 2.0
species: 891591
type: SpeciesReference

882601
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Arginine_C6H15N4O2
type: Species

904139
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: w-hydroxyl arachidonic acid_C20H31O3
type: Species

941735
stoichiometry: 1.0
species: 886275
type: SpeciesReference

905516
stoichiometry: 1.0
species: 891483
type: SpeciesReference

919317
stoichiometry: 2.0
species: 890362
type: SpeciesReference

904789
stoichiometry: 1.0
species: 896196
type: SpeciesReference

908391
product: 977202
product: 977275
product: 977226
reactant: 977178
reversible: false
is: ENSPTRG00000008302.3
is: http://identifiers.org/ec-code/2.4.99.4
reactant: 977166
reactant: 977117
type: Reaction
reactant: 977153
reactant: 977105
product: 977263
fast: false
reactant: 977141
product: 977214
product: 977238
notes: R_S23T4g subsystem: Keratan sulfate biosynthesis R_S23T4g equation: [g] : cmpacna + ksii_core4_pre1 --> cmp + h + ksii_core4_pre2 R_ST3GAL21g subsystem: Sphingolipid Metabolism R_ST3GAL21g equation: [g] : cmpacna + ga1_hs --> cmp + gm1b_hs + h R_ST3GAL22g subsystem: Sphingolipid Metabolism R_ST3GAL22g equation: [g] : cmpacna + gm1_hs --> cmp + gd1a_hs + h R_SIAT4Bg subsystem: Sphingolipid Metabolism R_SIAT4Bg equation: [g] : cmpacna + galgbside_hs --> acngalgbside_hs + cmp + h R_S23T2g subsystem: Keratan sulfate biosynthesis R_S23T2g equation: [g] : cmpacna + core2 --> cmp + h + ksii_core2_pre1 R_ST3GAL23g subsystem: Sphingolipid Metabolism R_ST3GAL23g equation: [g] : cmpacna + gd1b_hs --> cmp + gt1b_hs + h
product: 977190
product: 977251
reactant: 977129

895871
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: trimannosyl-glucosaminyl-acylphosphatidylinositol (H4)_C49H88NO29PFULLRCO2FULLR2CO2
type: Species

980390
stoichiometry: 1.0
species: 880607
type: SpeciesReference

953760
stoichiometry: 2.0
species: 877698
type: SpeciesReference

893828
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 38_C54H91N3O41
type: Species

917273
stoichiometry: 1.0
species: 891579
type: SpeciesReference

008911
stoichiometry: 1.0
species: 903488
type: SpeciesReference

999512
stoichiometry: 1.0
species: 880571
type: SpeciesReference

994309
stoichiometry: 2.0
species: 896064
type: SpeciesReference

906350
stoichiometry: 1.0
species: 899045
type: SpeciesReference

984472
stoichiometry: 1.0
species: 883711
type: SpeciesReference

989714
stoichiometry: 1.0
species: 894020
type: SpeciesReference

923799
stoichiometry: 1.0
species: 882781
type: SpeciesReference

979462
stoichiometry: 1.0
species: 898901
type: SpeciesReference

005755
stoichiometry: 1.0
species: 876680
type: SpeciesReference

985380
stoichiometry: 1.0
species: 883759
type: SpeciesReference

003824
stoichiometry: 1.0
species: 893610
type: SpeciesReference

005081
stoichiometry: 1.0
species: 886312
type: SpeciesReference

893972
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I_C247H393N17O213S12X
type: Species

896813
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1D-myo-Inositol 1,4,5-trisphosphate_C6H9O15P3
type: Species

911483
product: 005381
is: ENSPTRG00000000264.2
is: http://identifiers.org/ec-code/1.1.1.21
fast: false
reactant: 005243
type: Reaction
reversible: false
is: ENSPTRG00000000265.2
reactant: 005256
product: 005393
reactant: 005282
reactant: 005308
product: 005345
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_LALDO2x subsystem: Pyruvate Metabolism R_LALDO2x equation: [c] : h + mthgxl + nadh --> lald-D + nad R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_PPDOx subsystem: Pyruvate Metabolism R_PPDOx equation: [c] : h + lald-D + nadh --> 12ppd-R + nad R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
reactant: 005295
is: ENSPTRG00000000263.4
reactant: 005269
product: 005369
product: 005405
reactant: 005321
reactant: 005230
product: 005417
product: 005357
product: 005333

915078
stoichiometry: 1.0
species: 897648
type: SpeciesReference

973049
stoichiometry: 1.0
species: 893647
type: SpeciesReference

890578
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Glycine betaine_C5H11NO2
type: Species

902872
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Thymidine_C10H14N2O5
type: Species

879979
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: R total 3 carnitine_CO2FULLR3C7H14NO2
type: Species

883880
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Choline phosphate_C5H13NO4P
type: Species

984364
stoichiometry: 1.0
species: 891507
type: SpeciesReference

910306
reversible: false
fast: false
reactant: 992946
reactant: 992970
name: Ubiquinone biosynthesis COQ7
type: Reaction
product: 993018
product: 993006
notes: R_COQ7m subsystem: Ubiquinone Biosynthesis R_COQ7m equation: [m] : 2dp6mobq_me + h + nadph + o2 --> 2dpmhobq + h2o + nadp
is: ENSPTRG00000007828.1
reactant: 992982
product: 992994
reactant: 992958

959446
stoichiometry: 1.0
species: 897516
type: SpeciesReference

997873
stoichiometry: 10.0
species: 897261
type: SpeciesReference

918784
stoichiometry: 1.0
species: 877988
type: SpeciesReference

891254
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Reduced glutathione_C10H16N3O6S
type: Species

991917
stoichiometry: 2.0
species: 897492
type: SpeciesReference

999224
stoichiometry: 1.0
species: 883167
type: SpeciesReference

010260
stoichiometry: 1.0
species: 900993
type: SpeciesReference

909675
stoichiometry: 1.0
species: 900075
type: SpeciesReference

907869
stoichiometry: 1.0
species: 896136
type: SpeciesReference

887498
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: dTMP_C10H13N2O8P
type: Species

913205
stoichiometry: 1.0
species: 895749
type: SpeciesReference

895326
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: lignoceryl carnitine_C31H61NO4
type: Species

892485
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 22_C37H56NO35S
type: Species

962211
stoichiometry: 2.0
species: 900244
type: SpeciesReference

955304
stoichiometry: 1.0
species: 897552
type: SpeciesReference

979353
stoichiometry: 1.0
species: 892909
type: SpeciesReference

914922
stoichiometry: 1.0
species: 887290
type: SpeciesReference

933237
stoichiometry: 1.0
species: 883832
type: SpeciesReference

983120
stoichiometry: 1.0
species: 882805
type: SpeciesReference

916755
stoichiometry: 1.0
species: 882541
type: SpeciesReference

924293
stoichiometry: 1.0
species: 882601
type: SpeciesReference

934589
stoichiometry: 2.0
species: 890362
type: SpeciesReference

949929
stoichiometry: 1.0
species: 895423
type: SpeciesReference

962886
stoichiometry: 1.0
species: 884802
type: SpeciesReference

880426
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Acetaldehyde_C2H4O
type: Species

909789
product: 989207
reactant: 989195
notes: R_DCT subsystem: Tyrosine metabolism R_DCT equation: [c] : L-dpchrm <==> 56dihindlcrbxlt
is: ENSPTRG00000001501.5
is: http://identifiers.org/ec-code/5.3.3.12
fast: false
reversible: true
name: Dopachrome tautomerase
type: Reaction

881342
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: ADPmannose_C16H23N5O15P2
type: Species

957825
stoichiometry: 1.0
species: 891531
type: SpeciesReference

002895
stoichiometry: 1.0
species: 887033
type: SpeciesReference

972577
stoichiometry: 3.0
species: 899530
type: SpeciesReference

960919
stoichiometry: 1.0
species: 893235
type: SpeciesReference

936048
stoichiometry: 1.0
species: 899686
type: SpeciesReference

893283
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Inosine_C10H12N4O5
type: Species

982422
stoichiometry: 1.0
species: 888188
type: SpeciesReference

968340
stoichiometry: 1.0
species: 882493
type: SpeciesReference

886745
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: (S)-Dihydroorotate_C5H5N2O4
type: Species

967231
stoichiometry: 1.0
species: 894987
type: SpeciesReference

902871
product: 927852
is: ENSPTRG00000012054.2
reactant: 927778
reactant: 927802
reactant: 927765
product: 927865
is: http://identifiers.org/ec-code/1.1.1.153
fast: false
type: Reaction
reactant: 927753
reversible: false
reactant: 927814
product: 927827
product: 927840
reactant: 927790
notes: R_SPRn subsystem: Tetrahydrobiopterin R_SPRn equation: [n] : 6pthp + (2) h + (2) nadph --> (2) nadp + thbpt R_SPR subsystem: Tetrahydrobiopterin R_SPR equation: [c] : 6pthp + (2) h + (2) nadph --> (2) nadp + thbpt

940464
stoichiometry: 1.0
species: 901426
type: SpeciesReference

896921
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: myo-Inositol hexakisphosphate_C6H6O24P6
type: Species

895980
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

898080
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: O2_O2
type: Species

900582
type: Reaction
product: 910379
product: 910319
is: ENSPTRG00000001888.4
product: 910343
reactant: 910209
fast: false
reactant: 910197
product: 910355
reactant: 910257
notes: R_PI4P3K subsystem: Inositol Phosphate Metabolism R_PI4P3K equation: [c] : atp + pail4p_hs --> adp + h + pail34p_hs R_PIK3er subsystem: Inositol Phosphate Metabolism R_PIK3er equation: [r] : atp + pail_hs --> adp + h + pail3p_hs R_PIK3 subsystem: Inositol Phosphate Metabolism R_PIK3 equation: [c] : atp + pail_hs --> adp + h + pail3p_hs R_PI5P3Ker subsystem: Inositol Phosphate Metabolism R_PI5P3Ker equation: [r] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI5P3K subsystem: Inositol Phosphate Metabolism R_PI5P3K equation: [c] : atp + pail5p_hs --> adp + h + pail35p_hs R_PI4P3Ker subsystem: Inositol Phosphate Metabolism R_PI4P3Ker equation: [r] : atp + pail4p_hs --> adp + h + pail34p_hs
product: 910331
reversible: false
reactant: 910233
product: 910307
product: 910294
reactant: 910269
product: 910403
reactant: 910282
reactant: 910221
product: 910367
reactant: 910245
is: http://identifiers.org/ec-code/2.7.1.137
product: 910391

932415
stoichiometry: 1.0
species: 897321
type: SpeciesReference

909105
notes: R_AGTim subsystem: Alanine and Aspartate Metabolism R_AGTim equation: [m] : ala-L + glx --> gly + pyr
is: ENSPTRG00000016355.1
is: ENSPTRG00000016786.3
fast: false
product: 982974
is: http://identifiers.org/ec-code/2.6.1.44
reactant: 982962
name: alanine-glyoxylate transaminase (irreversible), mitochondrial
product: 982986
reactant: 982950
type: Reaction
reversible: false

930991
stoichiometry: 36.0
species: 891567
type: SpeciesReference

935385
stoichiometry: 3.0
species: 879078
type: SpeciesReference

993838
stoichiometry: 3.0
species: 897273
type: SpeciesReference

925572
stoichiometry: 3.0
species: 899530
type: SpeciesReference

003150
stoichiometry: 35.0
species: 891676
type: SpeciesReference

908852
product: 981614
fast: false
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p
reversible: true
is: http://identifiers.org/ec-code/5.4.2.8
is: ENSPTRG00000007748.3
reactant: 981601
type: Reaction
name: phosphomannomutase
is: ENSPTRG00000014432.2

006164
stoichiometry: 1.0
species: 890470
type: SpeciesReference

910524
stoichiometry: 1.0
species: 885744
type: SpeciesReference

005863
stoichiometry: 4.0
species: 891591
type: SpeciesReference

907485
reactant: 966371
notes: R_SUCOASm subsystem: Citric Acid Cycle R_SUCOASm equation: [m] : atp + coa + succ <==> adp + pi + succoa R_MECOALm subsystem: C5-Branched dibasic acid metabolism R_MECOALm equation: [m] : atp + coa + mescon <==> adp + mescoa + pi R_ITCOALm subsystem: C5-Branched dibasic acid metabolism R_ITCOALm equation: [m] : atp + coa + itacon <==> adp + itaccoa + pi
type: Reaction
reactant: 966383
product: 966419
product: 966407
is: ENSPTRG00000005859.4
reactant: 966359
fast: false
is: http://identifiers.org/ec-code/6.2.1.5
reversible: true
reactant: 966347
product: 966443
product: 966431
product: 966395
reactant: 966335

906355
reactant: 958597
type: Reaction
is: ENSPTRG00000010080.3
fast: false
product: 958609
product: 958621
reactant: 958573
reactant: 958585
notes: R_3DSPHR subsystem: Sphingolipid Metabolism R_3DSPHR equation: [c] : 3dsphgn + h + nadph --> nadp + sphgn
is: http://identifiers.org/ec-code/1.1.1.102
reversible: false
name: _3-Dehydrosphinganine reductase

921651
stoichiometry: 2.0
species: 881837
type: SpeciesReference

924076
stoichiometry: 1.0
species: 885550
type: SpeciesReference

968569
stoichiometry: 1.0
species: 882613
type: SpeciesReference

900437
is: http://identifiers.org/ec-code/4.2.3.1
reactant: 908922
reversible: false
fast: false
type: Reaction
notes: R_THRS subsystem: Glycine, Serine, and Threonine Metabolism R_THRS equation: [c] : h2o + phom --> pi + thr-L
is: ENSPTRG00000002368.3
product: 908946
name: threonine synthase
product: 908934
reactant: 908910

960534
stoichiometry: 5.0
species: 882781
type: SpeciesReference

951527
stoichiometry: 1.0
species: 900617
type: SpeciesReference

913918
stoichiometry: 1.0
species: 900945
type: SpeciesReference

999891
stoichiometry: 1.0
species: 890326
type: SpeciesReference

919209
stoichiometry: 2.0
species: 891591
type: SpeciesReference

899214
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: phosphatidylethanolamine (homo sapiens)_C5H12NO4PFULLRCO2FULLR2CO2
type: Species

896160
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: (alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog_C1725H2840N20O620P20
type: Species

907171
stoichiometry: 1.0
species: 885188
type: SpeciesReference

000699
stoichiometry: 1.0
species: 876632
type: SpeciesReference

970226
stoichiometry: 1.0
species: 891591
type: SpeciesReference

991845
stoichiometry: 1.0
species: 897407
type: SpeciesReference

999669
stoichiometry: 1.0
species: 877963
type: SpeciesReference

923642
stoichiometry: 2.0
species: 891591
type: SpeciesReference

998585
stoichiometry: 1.0
species: 894212
type: SpeciesReference

877662
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3-Decaprenyl-4-hydroxybenzoate_C57H85O3
type: Species

956895
stoichiometry: 1.0
species: 895580
type: SpeciesReference

878036
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _3-Oxodecanoyl-CoA_C31H48N7O18P3S
type: Species

949181
stoichiometry: 1.0
species: 894831
type: SpeciesReference

878727
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5,6-Dihydroxyindole-2-carboxylate_C9H6NO4
type: Species

943354
stoichiometry: 3.0
species: 881620
type: SpeciesReference

908393
stoichiometry: 1.0
species: 891483
type: SpeciesReference

955919
stoichiometry: 1.0
species: 896933
type: SpeciesReference

895217
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Leukotriene C4_C30H45N3O9S
type: Species

962102
stoichiometry: 1.0
species: 889250
type: SpeciesReference

974593
stoichiometry: 3.0
species: 899578
type: SpeciesReference

968232
stoichiometry: 1.0
species: 892801
type: SpeciesReference

982578
stoichiometry: 1.0
species: 889651
type: SpeciesReference

903403
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Tyrosine_C9H11NO3
type: Species

907172
reactant: 963771
fast: false
reactant: 963759
product: 963831
product: 963819
reversible: false
product: 963843
type: Reaction
is: ENSPTRG00000013211.4
product: 963783
notes: R_PNTK subsystem: CoA Biosynthesis R_PNTK equation: [c] : atp + pnto-R --> 4ppan + adp + h R_PNTKm subsystem: CoA Biosynthesis R_PNTKm equation: [m] : atp + pnto-R --> 4ppan + adp + h
is: http://identifiers.org/ec-code/2.7.1.33
reactant: 963735
product: 963795
product: 963807
reactant: 963747

979245
stoichiometry: 3.0
species: 889996
type: SpeciesReference

953192
stoichiometry: 1.0
species: 880256
type: SpeciesReference

881234
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Adenosine_C10H13N5O4
type: Species

993730
stoichiometry: 1.0
species: 884391
type: SpeciesReference

945097
stoichiometry: 1.0
species: 892655
type: SpeciesReference

002486
stoichiometry: 5.0
species: 890518
type: SpeciesReference

999115
stoichiometry: 3.0
species: 891616
type: SpeciesReference

950133
stoichiometry: 1.0
species: 903341
type: SpeciesReference

908850
stoichiometry: 1.0
species: 880486
type: SpeciesReference

887046
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _4,8 dimethylnonanoyl carnitine_C18H37NO4
type: Species

941432
stoichiometry: 1.0
species: 887278
type: SpeciesReference

985492
stoichiometry: 1.0
species: 882986
type: SpeciesReference

910522
reactant: 994455
reversible: false
reactant: 994346
product: 994623
product: 994587
reactant: 994321
product: 994563
type: Reaction
product: 994551
reactant: 994443
product: 994539
reactant: 994394
product: 994611
product: 994491
reactant: 994419
reactant: 994358
is: http://identifiers.org/ec-code/1.8.3.1
reactant: 994407
product: 994479
reactant: 994467
product: 994527
product: 994515
fast: false
reactant: 994370
reactant: 994334
reactant: 994383
is: http://identifiers.org/ec-code/3.2.1.113
reactant: 994431
reactant: 994309
product: 994503
product: 994599
is: ENSPTRG00000018558.2
notes: R_MM5bg subsystem: N-Glycan Biosynthesis R_MM5bg equation: [g] : h2o + m5masnB1 --> m4masn + man R_MM7Cbg subsystem: N-Glycan Biosynthesis R_MM7Cbg equation: [g] : h2o + m7masnC --> m6masnC + man R_MM6B2g subsystem: N-Glycan Biosynthesis R_MM6B2g equation: [g] : h2o + m6masnB2 --> m5masnB2 + man R_MM6bg subsystem: N-Glycan Biosynthesis R_MM6bg equation: [g] : h2o + m6masnC --> m5masnC + man R_MM8Ag subsystem: N-Glycan Biosynthesis R_MM8Ag equation: [g] : h2o + m8masn --> m7masnA + man R_SULFOX subsystem: Cysteine Metabolism R_SULFOX equation: (2) ficytC[m] + h2o[c] + so3[c] --> (2) focytC[m] + (2) h[c] + so4[c] R_MM8Cg subsystem: N-Glycan Biosynthesis R_MM8Cg equation: [g] : h2o + m8masn --> m7masnC + man R_MM7Cag subsystem: N-Glycan Biosynthesis R_MM7Cag equation: [g] : h2o + m7masnA --> m6masnC + man R_MM6B1ag subsystem: N-Glycan Biosynthesis R_MM6B1ag equation: [g] : h2o + m6masnB1 --> m5masnB1 + man R_MM7B2g subsystem: N-Glycan Biosynthesis R_MM7B2g equation: [g] : h2o + m7masnB --> m6masnB2 + man R_MM6B1bg subsystem: N-Glycan Biosynthesis R_MM6B1bg equation: [g] : h2o + m6masnB2 --> m5masnB1 + man R_MM5ag subsystem: N-Glycan Biosynthesis R_MM5ag equation: [g] : h2o + m5masnC --> m4masn + man R_MM5cg subsystem: N-Glycan Biosynthesis R_MM5cg equation: [g] : h2o + m5masnB2 --> m4masn + man R_MM7B1g subsystem: N-Glycan Biosynthesis R_MM7B1g equation: [g] : h2o + m7masnB --> m6masnB1 + man
product: 994575

883591
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2
type: Species

891363
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Guanine_C5H5N5O
type: Species

910970
stoichiometry: 1.0
species: 898636
type: SpeciesReference

997764
stoichiometry: 1.0
species: 900220
type: SpeciesReference

902763
fast: false
reactant: 927139
is: http://identifiers.org/ec-code/1.4.3.5
type: Reaction
reactant: 927115
is: ENSPTRG00000009343.3
reactant: 927127
product: 927163
product: 927187
notes: R_PDX5PO subsystem: Vitamin B6 Metabolism R_PDX5PO equation: [c] : o2 + pdx5p <==> h2o2 + pydx5p R_PYAM5POr subsystem: Vitamin B6 Metabolism R_PYAM5POr equation: [c] : h2o + o2 + pyam5p <==> h2o2 + nh4 + pydx5p
reactant: 927151
reversible: true
product: 927175

932114
stoichiometry: 2.0
species: 898612
type: SpeciesReference

878144
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Sulfino-L-alanine_C3H5NO4S
type: Species

953870
stoichiometry: 1.0
species: 903596
type: SpeciesReference

964204
stoichiometry: 1.0
species: 878132
type: SpeciesReference

940355
stoichiometry: 1.0
species: 887558
type: SpeciesReference

963297
stoichiometry: 1.0
species: 899554
type: SpeciesReference

909785
stoichiometry: 1.0
species: 878557
type: SpeciesReference

933346
stoichiometry: 1.0
species: 890264
type: SpeciesReference

925680
stoichiometry: 1.0
species: 899530
type: SpeciesReference

911150
stoichiometry: 2.0
species: 891591
type: SpeciesReference

924184
stoichiometry: 1.0
species: 901874
type: SpeciesReference

967388
stoichiometry: 1.0
species: 888249
type: SpeciesReference

935843
stoichiometry: 1.0
species: 898297
type: SpeciesReference

890686
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Glycolate_C2H3O3
type: Species

933941
stoichiometry: 1.0
species: 890301
type: SpeciesReference

916863
stoichiometry: 1.0
species: 902366
type: SpeciesReference

945954
stoichiometry: 1.0
species: 899445
type: SpeciesReference

981614
stoichiometry: 1.0
species: 896390
type: SpeciesReference

879246
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: pentaglutamyl folate (THF)_C39H45N11O18
type: Species

888732
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Formyl-CoA_C22H36N7O17P3S
type: Species

919909
stoichiometry: 1.0
species: 901970
type: SpeciesReference

930894
stoichiometry: 1.0
species: 891495
type: SpeciesReference

884693
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Carnitine_C7H15NO3
type: Species

900172
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: D-Proline_C5H9NO2
type: Species

903405
modifier: 931994
reactant: 931848
is: ENSPTRG00000011327.2
product: 931910
modifier: 931946
is: http://identifiers.org/ec-code/6.3.5.5
modifier: 931934
reactant: 931836
reactant: 931824
reversible: false
product: 931922
is: http://identifiers.org/ec-code/3.5.2.3
fast: false
modifier: 931958
product: 931872
is: http://identifiers.org/ec-code/2.1.3.2
notes: R_CBPS subsystem: Pyrimidine Biosynthesis R_CBPS equation: [c] : (2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi R_ASPCTr subsystem: Pyrimidine Biosynthesis R_ASPCTr equation: [c] : asp-L + cbp <==> cbasp + h + pi R_DHORTS subsystem: Pyrimidine Biosynthesis R_DHORTS equation: [c] : dhor-S + h2o <==> cbasp + h
modifier: 931982
modifier: 931970
product: 931885
product: 931898
modifier: 932006
type: Reaction
reactant: 931860

969730
stoichiometry: 1.0
species: 904320
type: SpeciesReference

962730
stoichiometry: 2.0
species: 891640
type: SpeciesReference

954276
stoichiometry: 1.0
species: 894951
type: SpeciesReference

923859
stoichiometry: 1.0
species: 879859
type: SpeciesReference

959701
stoichiometry: 2.0
species: 882781
type: SpeciesReference

910750
reactant: 996546
product: 996594
notes: R_DUTPDPn subsystem: Nucleotides R_DUTPDPn equation: [n] : dutp + h2o --> dump + h + ppi R_DUTPDPm subsystem: Nucleotides R_DUTPDPm equation: [m] : dutp + h2o --> dump + h + ppi
is: http://identifiers.org/ec-code/3.6.1.23
product: 996582
reactant: 996558
product: 996570
reversible: false
product: 996618
reactant: 996521
type: Reaction
reactant: 996534
product: 996606
is: ENSPTRG00000007044.4
product: 996630
fast: false

877468
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3,4-Dihydroxyphenylacetaldehyde_C8H8O3
type: Species

954119
stoichiometry: 1.0
species: 897888
type: SpeciesReference

925080
stoichiometry: 1.0
species: 900824
type: SpeciesReference

965792
stoichiometry: 1.0
species: 888866
type: SpeciesReference

922481
stoichiometry: 1.0
species: 901426
type: SpeciesReference

906619
type: Reaction
product: 960642
is: http://identifiers.org/ec-code/2.7.1.68
reversible: false
product: 960654
fast: false
reactant: 960558
reactant: 960546
reactant: 960534
notes: R_PI3P5K subsystem: Inositol Phosphate Metabolism R_PI3P5K equation: [c] : atp + pail3p_hs --> adp + h + pail35p_hs R_PI34P5K subsystem: Inositol Phosphate Metabolism R_PI34P5K equation: [c] : atp + pail34p_hs --> adp + h + pail345p_hs R_PIK5 subsystem: Inositol Phosphate Metabolism R_PIK5 equation: [c] : atp + pail_hs --> adp + h + pail5p_hs R_PI4P5K subsystem: Glycerophospholipid Metabolism R_PI4P5K equation: [c] : atp + pail4p_hs --> adp + h + pail45p_hs R_PI3P4K subsystem: Inositol Phosphate Metabolism R_PI3P4K equation: [c] : atp + pail3p_hs --> adp + h + pail34p_hs
is: ENSPTRG00000021001.4
product: 960606
product: 960594
is: ENSPTRG00000001282.5
is: ENSPTRG00000010273.2
product: 960666
product: 960630
product: 960618
reactant: 960582
reactant: 960570

000578
stoichiometry: 1.0
species: 878896
type: SpeciesReference

001953
stoichiometry: 1.0
species: 899795
type: SpeciesReference

915138
stoichiometry: 1.0
species: 898539
type: SpeciesReference

984628
stoichiometry: 1.0
species: 891218
type: SpeciesReference

925452
stoichiometry: 1.0
species: 890758
type: SpeciesReference

968763
stoichiometry: 2.0
species: 891591
type: SpeciesReference

926175
stoichiometry: 1.0
species: 879282
type: SpeciesReference

902764
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Thiamin monophosphate_C12H16N4O4PS
type: Species

924934
stoichiometry: 1.0
species: 888019
type: SpeciesReference

923569
stoichiometry: 1.0
species: 882781
type: SpeciesReference

887253
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Dolichyl phosphate D-mannose, human uterine homolog_C1085H1780O90P10
type: Species

969511
stoichiometry: 2.0
species: 889118
type: SpeciesReference

946302
stoichiometry: 1.0
species: 900812
type: SpeciesReference

007750
stoichiometry: 5.0
species: 881294
type: SpeciesReference

949060
stoichiometry: 1.0
species: 894236
type: SpeciesReference

920951
stoichiometry: 1.0
species: 896403
type: SpeciesReference

992365
stoichiometry: 1.0
species: 883374
type: SpeciesReference

928372
stoichiometry: 1.0
species: 888840
type: SpeciesReference

897261
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Sodium_Na
type: Species

899883
fast: false
is: ENSPTRG00000016845.4
reactant: 905721
type: Reaction
product: 905770
reactant: 905745
product: 905757
product: 905782
name: Hydroxymethylglutaryl CoA synthase (ir)
is: http://identifiers.org/ec-code/4.1.3.5
reversible: false
reactant: 905733
notes: R_HMGCOASi subsystem: Cholesterol Metabolism R_HMGCOASi equation: [c] : aacoa + accoa + h2o --> coa + h + hmgcoa

998140
stoichiometry: 2.0
species: 892933
type: SpeciesReference

982710
stoichiometry: 1.0
species: 882769
type: SpeciesReference

966154
stoichiometry: 4.0
species: 891591
type: SpeciesReference

942111
stoichiometry: 1.0
species: 893394
type: SpeciesReference

990209
stoichiometry: 1.0
species: 889551
type: SpeciesReference

933080
stoichiometry: 1.0
species: 884184
type: SpeciesReference

945362
stoichiometry: 1.0
species: 890240
type: SpeciesReference

892329
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 10_C55H80N3O70S8
type: Species

877516
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-(4-Hydroxyphenyl)pyruvate_C9H7O4
type: Species

888635
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Folate_C19H18N7O6
type: Species

897116
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: ((N-acetyl-D-glucosaminyl)2-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)_C50H83N4O35X
type: Species

976753
stoichiometry: 6.0
species: 885937
type: SpeciesReference

984796
stoichiometry: 1.0
species: 900436
type: SpeciesReference

927115
stoichiometry: 1.0
species: 899166
type: SpeciesReference

926031
stoichiometry: 18.0
species: 890350
type: SpeciesReference

918542
stoichiometry: 1.0
species: 898248
type: SpeciesReference

996035
stoichiometry: 1.0
species: 876849
type: SpeciesReference

907483
stoichiometry: 22.0
species: 898092
type: SpeciesReference

931185
stoichiometry: 1.0
species: 895629
type: SpeciesReference

950918
stoichiometry: 1.0
species: 884826
type: SpeciesReference

975522
stoichiometry: 1.0
species: 889704
type: SpeciesReference

935733
stoichiometry: 1.0
species: 898285
type: SpeciesReference

912541
stoichiometry: 1.0
species: 894975
type: SpeciesReference

941845
stoichiometry: 1.0
species: 887570
type: SpeciesReference

909106
stoichiometry: 3.0
species: 891591
type: SpeciesReference

950013
stoichiometry: 1.0
species: 902463
type: SpeciesReference

915477
stoichiometry: 1.0
species: 890216
type: SpeciesReference

905668
product: 952321
product: 952345
fast: false
reactant: 952285
reactant: 952261
reactant: 952273
reactant: 952249
reactant: 952297
notes: R_DESAT18_3 subsystem: Fatty acid elongation R_DESAT18_3 equation: [c] : h + nadh + o2 + stcoa --> (2) h2o + nad + odecoa R_DESAT18_5 subsystem: Fatty acid elongation R_DESAT18_5 equation: [c] : h + nadh + o2 + stcoa --> (2) h2o + nad + od2coa R_DESAT16_2 subsystem: Fatty acid elongation R_DESAT16_2 equation: [c] : h + nadh + o2 + pmtcoa --> (2) h2o + hdcoa + nad R_DESAT18_4 subsystem: Fatty acid elongation R_DESAT18_4 equation: [c] : h + nadh + o2 + stcoa --> (2) h2o + nad + vacccoa
product: 952369
product: 952333
type: Reaction
product: 952357
is: http://identifiers.org/ec-code/1.14.19.1
reversible: false
product: 952309
is: ENSPTRG00000002847.2

982866
stoichiometry: 1.0
species: 893418
type: SpeciesReference

977880
stoichiometry: 1.0
species: 895544
type: SpeciesReference

932826
stoichiometry: 1.0
species: 902740
type: SpeciesReference

962658
stoichiometry: 1.0
species: 893247
type: SpeciesReference

905957
product: 954215
reactant: 954203
notes: R_DCIm subsystem: Fatty Acid Metabolism R_DCIm equation: [m] : dd2coa <==> dd3coa
is: ENSPTRG00000007644.4
is: http://identifiers.org/ec-code/5.3.3.8
fast: false
reversible: true
name: dodecenoyl-Coenzyme A delta isomerase
type: Reaction

937641
stoichiometry: 1.0
species: 878607
type: SpeciesReference

961354
stoichiometry: 3.0
species: 899530
type: SpeciesReference

955652
stoichiometry: 1.0
species: 886624
type: SpeciesReference

900436
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Propenoyl-CoA_C24H34N7O17P3S
type: Species

969620
stoichiometry: 1.0
species: 889612
type: SpeciesReference

976259
stoichiometry: 1.0
species: 882781
type: SpeciesReference

972916
stoichiometry: 1.0
species: 894444
type: SpeciesReference

954823
stoichiometry: 1.0
species: 904224
type: SpeciesReference

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stoichiometry: 1.0
species: 902042
type: SpeciesReference

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stoichiometry: 1.0
species: 896958
type: SpeciesReference

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stoichiometry: 1.0
species: 891591
type: SpeciesReference

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stoichiometry: 1.0
species: 889454
type: SpeciesReference

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stoichiometry: 4.0
species: 891591
type: SpeciesReference

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stoichiometry: 1.0
species: 887618
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: dTTP_C10H13N2O14P3
type: Species

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stoichiometry: 1.0
species: 881258
type: SpeciesReference

960197
stoichiometry: 2.0
species: 880523
type: SpeciesReference

995817
stoichiometry: 1.0
species: 899530
type: SpeciesReference

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stoichiometry: 1.0
species: 897116
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate A (GalNAc4S-GlcA), B (IdoA2S-GalNAc4S), and E (GalNAc4,6diS-GlcA), precursor 1_C31H47NO31S2X
type: Species

903826
reactant: 934998
reversible: false
notes: R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh
reactant: 934938
product: 935144
reactant: 934962
reactant: 934902
product: 935108
product: 935071
fast: false
reactant: 934986
reactant: 935022
product: 935047
product: 935168
reactant: 934926
reactant: 935035
reactant: 934974
reactant: 934950
is: http://identifiers.org/ec-code/1.2.1.21
is: http://identifiers.org/ec-code/1.2.1.3
product: 935132
product: 935095
product: 935059
type: Reaction
reactant: 935010
product: 935120
product: 935083
reactant: 934914
product: 935156
product: 935180
is: ENSPTRG00000017185.3

921337
stoichiometry: 1.0
species: 881113
type: SpeciesReference

987542
stoichiometry: 13.0
species: 896427
type: SpeciesReference

920526
stoichiometry: 1.0
species: 891483
type: SpeciesReference

902439
fast: false
product: 924714
product: 924726
reactant: 924702
is: http://identifiers.org/ec-code/2.5.1.26
reversible: false
type: Reaction
reactant: 924690
product: 924739
is: ENSPTRG00000012680.2
notes: R_AGPSx subsystem: Glycerophospholipid Metabolism R_AGPSx equation: [x] : adhap_hs + alkylR1oh --> Rtotal + akdhap_hs + h
name: alkylglycerone phosphate synthase

904007
product: 936436
name: gamma-glutamylcyclotransferase
notes: R_GGLUCT subsystem: Glutathione Metabolism R_GGLUCT equation: gluala[e] --> 5oxpro[c] + ala-L[c]
is: ENSPTRG00000019041.3
is: http://identifiers.org/ec-code/2.3.2.4
reactant: 936412
fast: false
type: Reaction
product: 936424
reversible: false

911146
is: http://identifiers.org/ec-code/3.5.3.1
reactant: 000087
fast: false
notes: R_ARGN subsystem: Urea cycle/amino group metabolism R_ARGN equation: [c] : arg-L + h2o --> orn + urea
reactant: 000074
product: 000100
name: arginase
is: ENSPTRG00000018600.5
type: Reaction
product: 000113
reversible: false

002316
stoichiometry: 2.0
species: 881849
type: SpeciesReference

905878
stoichiometry: 1.0
species: 889875
type: SpeciesReference

958333
stoichiometry: 1.0
species: 889996
type: SpeciesReference

951731
stoichiometry: 1.0
species: 891640
type: SpeciesReference

931885
stoichiometry: 1.0
species: 890326
type: SpeciesReference

950580
stoichiometry: 6.0
species: 886045
type: SpeciesReference

920382
stoichiometry: 1.0
species: 893972
type: SpeciesReference

000253
stoichiometry: 1.0
species: 879402
type: SpeciesReference

941010
stoichiometry: 1.0
species: 897888
type: SpeciesReference

881957
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: hydroxy alkyl chain_C2H5OFULLR
type: Species

904573
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Xylulose 1-phosphate_C5H9O8P
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: (E)-carveol_C10H16O
type: Species

987278
stoichiometry: 1.0
species: 891483
type: SpeciesReference

978810
stoichiometry: 1.0
species: 890518
type: SpeciesReference

905104
is: ENSPTRG00000005149.3
type: Reaction
product: 945302
reactant: 945266
product: 945326
product: 945314
fast: false
notes: R_25VITD3Hm subsystem: Vitamin D R_25VITD3Hm equation: [m] : 25hvitd3 + h + nadph + o2 --> 1a25dhvitd3 + h2o + nadp R_25VITD2Hm subsystem: Vitamin D R_25VITD2Hm equation: [m] : 25hvitd2 + h + nadph + o2 --> 1a25dhvitd2 + h2o + nadp
reactant: 945278
reactant: 945254
product: 945290
reversible: false
reactant: 945241
reactant: 945229

918386
stoichiometry: 1.0
species: 891808
type: SpeciesReference

006396
stoichiometry: 1.0
species: 897443
type: SpeciesReference

953035
stoichiometry: 1.0
species: 903269
type: SpeciesReference

928633
stoichiometry: 1.0
species: 888998
type: SpeciesReference

890590
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Glycine betaine_C5H11NO2
type: Species

937967
stoichiometry: 1.0
species: 900860
type: SpeciesReference

989183
stoichiometry: 2.0
species: 899795
type: SpeciesReference

913822
stoichiometry: 1.0
species: 884463
type: SpeciesReference

927404
stoichiometry: 1.0
species: 884355
type: SpeciesReference

970455
stoichiometry: 1.0
species: 887485
type: SpeciesReference

950363
stoichiometry: 1.0
species: 902536
type: SpeciesReference

886877
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: dITP_C10H11N4O13P3
type: Species

885236
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), degradation product 1_C45H65N2O52S5
type: Species

994599
stoichiometry: 13.0
species: 896427
type: SpeciesReference

970382
stoichiometry: 1.0
species: 891640
type: SpeciesReference

979015
stoichiometry: 1.0
species: 904212
type: SpeciesReference

879643
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Dopachrome_C9H6NO4
type: Species

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stoichiometry: 1.0
species: 901741
type: SpeciesReference

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Glucuronate_C6H9O7
type: Species

893418
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: potassium_K
type: Species

898116
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Superoxide anion_O2
type: Species

928793
stoichiometry: 1.0
species: 886203
type: SpeciesReference

968124
stoichiometry: 2.0
species: 891591
type: SpeciesReference

934349
stoichiometry: 1.0
species: 894987
type: SpeciesReference

905103
stoichiometry: 1.0
species: 897443
type: SpeciesReference

894176
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 24_C191H306N13O158S7X
type: Species

881029
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
type: Species

009887
stoichiometry: 8.0
species: 884222
type: SpeciesReference

902211
reactant: 922283
is: ENSPTRG00000009446.3
notes: R_PRDX subsystem: Miscellaneous R_PRDX equation: [c] : h2o2 + meoh --> fald + (2) h2o
product: 922323
is: http://identifiers.org/ec-code/1.11.1.7
reversible: false
reactant: 922296
name: Peroxidase (multiple substrates)
type: Reaction
fast: false
product: 922309

936460
stoichiometry: 1.0
species: 898056
type: SpeciesReference

999320
stoichiometry: 1.0
species: 880365
type: SpeciesReference

001389
stoichiometry: 1.0
species: 892571
type: SpeciesReference

007302
stoichiometry: 1.0
species: 879835
type: SpeciesReference

895773
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: L-Lysine_C6H15N2O2
type: Species

895448
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Linoelaidyl carnitine_C25H45NO4
type: Species

952516
stoichiometry: 1.0
species: 877093
type: SpeciesReference

884367
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: CO2_CO2
type: Species

885744
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: diacylglycerol (homo sapiens)_C3H6OFULLRCO2FULLR2CO2
type: Species

985516
stoichiometry: 1.0
species: 888031
type: SpeciesReference

978277
stoichiometry: 1.0
species: 903016
type: SpeciesReference

896390
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Mannose 6-phosphate_C6H11O9P
type: Species

972227
stoichiometry: 1.0
species: 894651
type: SpeciesReference

892195
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: hydroxy nifedipine_C17H18N2O7
type: Species

952393
stoichiometry: 1.0
species: 881764
type: SpeciesReference

972094
stoichiometry: 1.0
species: 894843
type: SpeciesReference

961583
stoichiometry: 2.0
species: 897321
type: SpeciesReference

987254
stoichiometry: 2.0
species: 891591
type: SpeciesReference

889802
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: globoside (homo sapiens)_C44H79N2O22FULLRCO
type: Species

902438
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: tetracosapentaenoyl coenzyme A, n-6_C45H68N7O17P3S
type: Species

939751
stoichiometry: 1.0
species: 891628
type: SpeciesReference

969718
stoichiometry: 1.0
species: 880704
type: SpeciesReference

959206
stoichiometry: 1.0
species: 892994
type: SpeciesReference

953302
stoichiometry: 1.0
species: 877878
type: SpeciesReference

882505
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: arachidonic acid_C20H31O2
type: Species

990879
stoichiometry: 1.0
species: 903692
type: SpeciesReference

904006
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: UTP_C9H11N2O15P3
type: Species

906628
stoichiometry: 1.0
species: 893187
type: SpeciesReference

908547
stoichiometry: 2.0
species: 896607
type: SpeciesReference

967073
stoichiometry: 13.0
species: 897347
type: SpeciesReference

951138
stoichiometry: 1.0
species: 882090
type: SpeciesReference

968460
stoichiometry: 1.0
species: 899202
type: SpeciesReference

883022
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Bilirubin_C33H34N4O6
type: Species

006590
stoichiometry: 5.0
species: 891591
type: SpeciesReference

880462
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Acetyl-CoA_C23H34N7O17P3S
type: Species

916508
stoichiometry: 1.0
species: 887897
type: SpeciesReference

989292
stoichiometry: 1.0
species: 880535
type: SpeciesReference

899445
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Phenylpyruvate_C9H7O3
type: Species

881813
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: beta-Alanine_C3H7NO2
type: Species

966599
stoichiometry: 1.0
species: 882396
type: SpeciesReference

904285
fast: false
product: 939175
is: ENSPTRG00000003658.3
reversible: true
reactant: 939139
reactant: 939163
product: 939187
reactant: 939151
product: 939211
type: Reaction
product: 939199
notes: R_METtec subsystem: Transport, Extracellular R_METtec equation: met-L[e] <==> met-L[c] R_ILEtec subsystem: Transport, Extracellular R_ILEtec equation: ile-L[e] <==> ile-L[c] R_LEUtec subsystem: Transport, Extracellular R_LEUtec equation: leu-L[e] <==> leu-L[c] R_VALtec subsystem: Transport, Extracellular R_VALtec equation: val-L[e] <==> val-L[c]
reactant: 939127

939151
stoichiometry: 1.0
species: 904091
type: SpeciesReference

005417
stoichiometry: 1.0
species: 880535
type: SpeciesReference

897321
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

919752
stoichiometry: 1.0
species: 886745
type: SpeciesReference

924726
stoichiometry: 1.0
species: 880039
type: SpeciesReference

912771
stoichiometry: 2.0
species: 891278
type: SpeciesReference

900715
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Pyruvate_C3H3O3
type: Species

925248
stoichiometry: 4.0
species: 899530
type: SpeciesReference

957994
stoichiometry: 1.0
species: 888273
type: SpeciesReference

926621
stoichiometry: 1.0
species: 882493
type: SpeciesReference

881692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole_C8H12N3O7P
type: Species

880861
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
type: Species

887788
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: epiandrosterone_C19H28O3
type: Species

986759
stoichiometry: 1.0
species: 882673
type: SpeciesReference

889094
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (Gal)4 (Glc)1 (GlcNAc)3 (LFuc)1 (Cer)1_C78H135N4O46FULLRCO
type: Species

993367
stoichiometry: 1.0
species: 888346
type: SpeciesReference

971611
stoichiometry: 1.0
species: 891531
type: SpeciesReference

979678
stoichiometry: 2.0
species: 891664
type: SpeciesReference

877093
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate_C13H15N4O12P
type: Species

948760
stoichiometry: 2.0
species: 891616
type: SpeciesReference

909312
stoichiometry: 1.0
species: 884061
type: SpeciesReference

956076
stoichiometry: 8.0
species: 891591
type: SpeciesReference

959329
stoichiometry: 1.0
species: 890216
type: SpeciesReference

905873
notes: R_ECOAH1x subsystem: Tryptophan metabolism R_ECOAH1x equation: [x] : 3hbcoa <==> b2coa + h2o R_C2M26DCOAHLx subsystem: Limonene and pinene degradation R_C2M26DCOAHLx equation: [x] : c2m26dcoa + h2o <==> 3h26dm5coa R_T2M26DCOAHLx subsystem: Limonene and pinene degradation R_T2M26DCOAHLx equation: [x] : h2o + t2m26dcoa <==> 3h26dm5coa
reversible: true
product: 953748
reactant: 953724
fast: false
product: 953760
type: Reaction
is: ENSPTRG00000010940.3
reactant: 953700
reactant: 953688
product: 953736
reactant: 953712
is: http://identifiers.org/ec-code/4.2.1.17

910990
type: Reaction
reactant: 998260
is: http://identifiers.org/ec-code/3.2.1.18
is: ENSPTRG00000013049.2
product: 998272
reactant: 998248
product: 998285
fast: false
notes: R_SIAASE subsystem: N-Glycan Degradation R_SIAASE equation: [c] : (2) h2o + s2l2n2m2mn --> (2) acnam + l2n2m2mn
name: sialidase
reversible: false

010417
stoichiometry: 1.0
species: 878144
type: SpeciesReference

005204
stoichiometry: 1.0
species: 886081
type: SpeciesReference

949279
stoichiometry: 1.0
species: 877348
type: SpeciesReference

877722
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

944135
stoichiometry: 1.0
species: 890989
type: SpeciesReference

958657
stoichiometry: 4.0
species: 891640
type: SpeciesReference

913073
stoichiometry: 1.0
species: 903440
type: SpeciesReference

927260
stoichiometry: 1.0
species: 883675
type: SpeciesReference

001749
stoichiometry: 1.0
species: 894723
type: SpeciesReference

977651
stoichiometry: 1.0
species: 892801
type: SpeciesReference

909809
stoichiometry: 3.0
species: 897347
type: SpeciesReference

962427
stoichiometry: 2.0
species: 897261
type: SpeciesReference

928926
stoichiometry: 1.0
species: 893175
type: SpeciesReference

965888
stoichiometry: 1.0
species: 901970
type: SpeciesReference

913701
stoichiometry: 2.0
species: 877166
type: SpeciesReference

900592
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Putrescine_C4H14N2
type: Species

992571
stoichiometry: 2.0
species: 891483
type: SpeciesReference

929239
stoichiometry: 1.0
species: 901982
type: SpeciesReference

001099
stoichiometry: 1.0
species: 880462
type: SpeciesReference

990415
stoichiometry: 1.0
species: 894310
type: SpeciesReference

892909
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Hypotaurine_C2H6NO2S
type: Species

947485
stoichiometry: 1.0
species: 894116
type: SpeciesReference

902210
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: taurocholic acid_C26H45NO7S
type: Species

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constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: hexacosanoyl carnitine_C33H65NO4
type: Species

994745
stoichiometry: 1.0
species: 891555
type: SpeciesReference

934481
stoichiometry: 1.0
species: 881137
type: SpeciesReference

996485
stoichiometry: 1.0
species: 884391
type: SpeciesReference

995525
stoichiometry: 1.0
species: 899638
type: SpeciesReference

986022
stoichiometry: 4.0
species: 891591
type: SpeciesReference

903824
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Uracil_C4H4N2O2
type: Species

948988
stoichiometry: 1.0
species: 894867
type: SpeciesReference

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stoichiometry: 1.0
species: 902258
type: SpeciesReference

891218
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Oxidized glutathione_C20H30N6O12S2
type: Species

888200
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Estrone 3-sulfate_C18H21O5S
type: Species

904574
reactant: 941384
reversible: false
notes: R_DOLPGT1_Ler subsystem: N-Glycan Biosynthesis R_DOLPGT1_Ler equation: [r] : (0.1) dolglcp_L + (0.1) m8mpdol_L --> (0.1) dolp_L + (0.1) g1m8mpdol_L + h R_DOLPGT1_Uer subsystem: N-Glycan Biosynthesis R_DOLPGT1_Uer equation: [r] : (0.1) dolglcp_U + (0.1) m8mpdol_U --> (0.1) dolp_U + (0.1) g1m8mpdol_U + h
product: 941432
is: ENSPTRG00000000815.4
product: 941468
product: 941444
product: 941480
reactant: 941396
product: 941456
reactant: 941420
fast: false
type: Reaction
reactant: 941408

916430
stoichiometry: 1.0
species: 891880
type: SpeciesReference

005295
stoichiometry: 8.0
species: 891591
type: SpeciesReference

949593
stoichiometry: 1.0
species: 882529
type: SpeciesReference

982181
stoichiometry: 1.0
species: 896909
type: SpeciesReference

999681
stoichiometry: 3.0
species: 890362
type: SpeciesReference

002194
stoichiometry: 1.0
species: 891591
type: SpeciesReference

885019
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 2_C37H55NO38S2
type: Species

901282
type: Reaction
notes: R_CYSTGLUex subsystem: Transport, Extracellular R_CYSTGLUex equation: Lcystin[e] + glu-L[c] --> Lcystin[c] + glu-L[e]
product: 915283
is: ENSPTRG00000016446.4
name: L-cystine/L-glutamate exchanger
reversible: false
reactant: 915259
product: 915271
fast: false
reactant: 915247

942836
stoichiometry: 1.0
species: 884145
type: SpeciesReference

930220
stoichiometry: 1.0
species: 881077
type: SpeciesReference

894273
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 31_C227H363N16O189S9X
type: Species

008707
stoichiometry: 1.0
species: 880027
type: SpeciesReference

891519
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: H2O_H2O
type: Species

935505
stoichiometry: 10.0
species: 891591
type: SpeciesReference

876692
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _11-Deoxycortisol_C21H30O4
type: Species

988784
stoichiometry: 1.0
species: 880317
type: SpeciesReference

906511
is: ENSPTRG00000033891.1
type: Reaction
reversible: false
reactant: 959857
is: ENSPTRG00000001908.4
reactant: 959869
reactant: 959881
product: 959893
notes: R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c] R_CLHCOtex subsystem: Transport, Extracellular R_CLHCOtex equation: cl[e] + (2) hco3[c] --> cl[c] + (2) hco3[e]
is: ENSPTRG00000018095.5
product: 959918
product: 959906
fast: false

894927
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Lactate_C3H5O3
type: Species

904284
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _7 alpha-Hydroxycholesterol_C27H46O2
type: Species

929699
stoichiometry: 1.0
species: 904489
type: SpeciesReference

902559
is: ENSPTRG00000021665.3
reactant: 925080
product: 925116
product: 925104
reversible: true
product: 925128
fast: false
reactant: 925092
notes: R_PRPPS subsystem: Pentose Phosphate Pathway R_PRPPS equation: [c] : atp + r5p <==> amp + h + prpp
is: http://identifiers.org/ec-code/2.7.6.1
name: phosphoribosylpyrophosphate synthetase
is: ENSPTRG00000022163.4
type: Reaction

983228
stoichiometry: 2.0
species: 891555
type: SpeciesReference

930664
stoichiometry: 1.0
species: 884013
type: SpeciesReference

937412
stoichiometry: 1.0
species: 904188
type: SpeciesReference

991196
stoichiometry: 1.0
species: 884085
type: SpeciesReference

908430
product: 977688
product: 977578
is: ENSPTRG00000020526.3
notes: R_GLCAT9g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT9g equation: [g] : hs_pre7 + udpglcur --> h + hs_pre8 + udp R_GLCAT6g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT6g equation: [g] : hs_pre1 + udpglcur --> h + hs_pre2 + udp R_GLCNACT2g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT2g equation: [g] : hs_pre2 + uacgam --> h + hs_pre3 + udp R_GLCAT8g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT8g equation: [g] : hs_pre5 + udpglcur --> h + hs_pre6 + udp R_GLCNACT5g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT5g equation: [g] : hs_pre8 + uacgam --> h + hs_pre9 + udp R_GLCNACT3g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT3g equation: [g] : hs_pre4 + uacgam --> h + hs_pre5 + udp R_GLCAT7g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCAT7g equation: [g] : hs_pre3 + udpglcur --> h + hs_pre4 + udp R_GLCNACT4g subsystem: Chondroitin / heparan sulfate biosynthesis R_GLCNACT4g equation: [g] : hs_pre6 + uacgam --> h + hs_pre7 + udp
reversible: false
reactant: 977482
product: 977675
fast: false
type: Reaction
product: 977639
product: 977663
product: 977651
product: 977627
product: 977590
product: 977615
reactant: 977494
reactant: 977554
reactant: 977470
reactant: 977506
reactant: 977530
is: ENSPTRG00000003528.5
product: 977602
reactant: 977518
reactant: 977566
reactant: 977542
reactant: 977458

901281
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Se-Adenosylselenomethionine_C15H23N6O5Se
type: Species

963602
stoichiometry: 5.0
species: 881897
type: SpeciesReference

884512
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Core 4_C24H40N3O15X
type: Species

992680
stoichiometry: 1.0
species: 882781
type: SpeciesReference

946098
stoichiometry: 1.0
species: 891652
type: SpeciesReference

940792
stoichiometry: 1.0
species: 883058
type: SpeciesReference

956184
stoichiometry: 1.0
species: 887314
type: SpeciesReference

009659
stoichiometry: 2.0
species: 891591
type: SpeciesReference

912662
stoichiometry: 1.0
species: 880365
type: SpeciesReference

981784
stoichiometry: 1.0
species: 878751
type: SpeciesReference

932561
stoichiometry: 1.0
species: 891591
type: SpeciesReference

979787
stoichiometry: 1.0
species: 879162
type: SpeciesReference

901064
fast: false
type: Reaction
is: http://identifiers.org/ec-code/1.15.1.1
reactant: 913846
reversible: false
product: 913870
reactant: 913858
name: superoxide dismutase
is: ENSPTRG00000018757.5
product: 913882
notes: R_SPODMm subsystem: ROS Detoxification R_SPODMm equation: [m] : (2) h + (2) o2s --> h2o2 + o2

962319
stoichiometry: 1.0
species: 898032
type: SpeciesReference

992897
stoichiometry: 1.0
species: 888708
type: SpeciesReference

988373
stoichiometry: 1.0
species: 883155
type: SpeciesReference

926512
stoichiometry: 2.0
species: 903488
type: SpeciesReference

986313
stoichiometry: 23.0
species: 891591
type: SpeciesReference

902019
product: 920418
product: 920382
product: 920466
fast: false
product: 920430
reactant: 920333
reactant: 920321
product: 920406
product: 920394
reactant: 920357
type: Reaction
reactant: 920345
reactant: 920369
is: ENSPTRG00000002607.3
is: http://identifiers.org/ec-code/2.8.2.17
product: 920454
product: 920442
reactant: 920285
reversible: false
product: 920478
notes: R_S6T3g subsystem: Keratan sulfate biosynthesis R_S6T3g equation: [g] : ksii_core2_pre10 + paps --> h + ksii_core2 + pap R_S6T24g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T24g equation: [g] : cs_e_pre4 + paps --> cs_e_pre5b + h + pap R_S6T20g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T20g equation: [g] : cs_c_pre3 + paps --> cspg_c + h + pap R_S6T19g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T19g equation: [g] : cs_pre + (2) paps --> cs_c,d,e_pre1 + (2) h + (2) pap R_S6T18g subsystem: Keratan sulfate biosynthesis R_S6T18g equation: [g] : ksii_core4_pre10 + paps --> h + ksii_core4 + pap R_S6T15g subsystem: Keratan sulfate biosynthesis R_S6T15g equation: [g] : ksi_pre36 + paps --> h + ksi + pap R_S6T21g subsystem: Chondroitin / heparan sulfate biosynthesis R_S6T21g equation: [g] : cs_d_pre4 + paps --> cs_d_pre5 + h + pap
reactant: 920309
reactant: 920297

993210
stoichiometry: 1.0
species: 890494
type: SpeciesReference

967520
stoichiometry: 1.0
species: 902632
type: SpeciesReference

877878
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Iodo-L-tyrosine_C9H10INO3
type: Species

958765
stoichiometry: 1.0
species: 888127
type: SpeciesReference

886191
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _7-Dehydrodesmosterol_C27H42O
type: Species

977868
stoichiometry: 1.0
species: 902426
type: SpeciesReference

919643
stoichiometry: 1.0
species: 886588
type: SpeciesReference

009055
stoichiometry: 9.0
species: 898032
type: SpeciesReference

969608
stoichiometry: 10.0
species: 903488
type: SpeciesReference

942607
stoichiometry: 1.0
species: 902524
type: SpeciesReference

973061
stoichiometry: 1.0
species: 894493
type: SpeciesReference

985950
stoichiometry: 2.0
species: 888394
type: SpeciesReference

965064
stoichiometry: 11.0
species: 897636
type: SpeciesReference

994189
stoichiometry: 1.0
species: 882781
type: SpeciesReference

907039
stoichiometry: 1.0
species: 883759
type: SpeciesReference

915597
stoichiometry: 1.0
species: 878301
type: SpeciesReference

911258
stoichiometry: 3.0
species: 891616
type: SpeciesReference

971767
stoichiometry: 1.0
species: 894795
type: SpeciesReference

926019
stoichiometry: 1.0
species: 876512
type: SpeciesReference

894383
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 6_C107H174N7O80SX
type: Species

976040
stoichiometry: 1.0
species: 881258
type: SpeciesReference

986867
stoichiometry: 1.0
species: 889310
type: SpeciesReference

965779
stoichiometry: 1.0
species: 888950
type: SpeciesReference

995130
stoichiometry: 1.0
species: 886925
type: SpeciesReference

944026
stoichiometry: 1.0
species: 891591
type: SpeciesReference

929348
stoichiometry: 1.0
species: 901886
type: SpeciesReference

977542
stoichiometry: 1.0
species: 892789
type: SpeciesReference

979883
stoichiometry: 1.0
species: 880195
type: SpeciesReference

909918
stoichiometry: 1.0
species: 881258
type: SpeciesReference

995243
stoichiometry: 2.0
species: 883264
type: SpeciesReference

878847
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5alpha-Dihydrotestosterone sulfate_C19H29O5S
type: Species

929588
stoichiometry: 1.0
species: 899530
type: SpeciesReference

883868
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Choline phosphate_C5H13NO4P
type: Species

974135
stoichiometry: 1.0
species: 885490
type: SpeciesReference

901814
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S
type: Species

010526
stoichiometry: 2.0
species: 891471
type: SpeciesReference

901549
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Sulfate_O4S
type: Species

993622
stoichiometry: 1.0
species: 903909
type: SpeciesReference

899650
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Palmitoyl-CoA (n-C16:0CoA)_C37H62N7O17P3S
type: Species

930556
stoichiometry: 1.0
species: 881632
type: SpeciesReference

879102
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-Hydroxykynurenine_C10H12N2O4
type: Species

891628
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: H+_H
type: Species

926307
stoichiometry: 1.0
species: 886588
type: SpeciesReference

992461
stoichiometry: 1.0
species: 877553
type: SpeciesReference

983954
stoichiometry: 1.0
species: 884910
type: SpeciesReference

932850
stoichiometry: 1.0
species: 891604
type: SpeciesReference

899723
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Propionate (n-C3:0)_C3H5O2
type: Species

908433
stoichiometry: 1.0
species: 880317
type: SpeciesReference

902667
reversible: false
product: 926307
name: Fe(III) reduction (ascorbate)
fast: false
reactant: 926283
is: ENSPTRG00000012634.3
notes: R_FE3R2e subsystem: Heme Biosynthesis R_FE3R2e equation: [e] : ascb-L + (2) fe3 --> dhdascb + (2) fe2 + (2) h
reactant: 926271
type: Reaction
product: 926320
product: 926295

923206
stoichiometry: 1.0
species: 903909
type: SpeciesReference

007738
stoichiometry: 3.0
species: 896740
type: SpeciesReference

897672
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Ammonium_H4N
type: Species

876584
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22
type: Species

971828
stoichiometry: 1.0
species: 894044
type: SpeciesReference

882901
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cis-beta-D-Glucosyl-2-hydroxycinnamate_C15H18O8
type: Species

910882
reactant: 997244
type: Reaction
notes: R_OPAHir subsystem: Glutathione Metabolism R_OPAHir equation: [c] : 5oxpro + atp + (2) h2o --> adp + glu-L + h + pi
product: 997268
reactant: 997220
product: 997256
reversible: false
product: 997292
is: http://identifiers.org/ec-code/3.5.2.9
name: _5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)
product: 997280
fast: false
is: ENSPTRG00000020676.5
reactant: 997232

996376
stoichiometry: 2.0
species: 891483
type: SpeciesReference

901815
reactant: 918314
product: 918326
product: 918362
type: Reaction
product: 918374
reactant: 918290
product: 918338
is: ENSPTRG00000021929.5
reactant: 918302
fast: false
product: 918350
reactant: 918265
reactant: 918277
reversible: true
notes: R_HACD1m subsystem: Tryptophan metabolism R_HACD1m equation: [m] : aacoa + h + nadh <==> 3hbcoa + nad R_HACD9m subsystem: Valine, Leucine, and Isoleucine Metabolism R_HACD9m equation: [m] : 3hmbcoa + nad <==> 2maacoa + h + nadh
is: http://identifiers.org/ec-code/1.1.1.35

884403
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Coenzyme A_C21H32N7O16P3S
type: Species

008815
stoichiometry: 2.0
species: 897516
type: SpeciesReference

964532
stoichiometry: 2.0
species: 897091
type: SpeciesReference

990123
stoichiometry: 1.0
species: 889514
type: SpeciesReference

975390
stoichiometry: 2.0
species: 884270
type: SpeciesReference

954131
stoichiometry: 2.0
species: 882030
type: SpeciesReference

991087
stoichiometry: 1.0
species: 904079
type: SpeciesReference

965210
stoichiometry: 1.0
species: 897395
type: SpeciesReference

009585
stoichiometry: 1.0
species: 884645
type: SpeciesReference

951887
stoichiometry: 1.0
species: 904573
type: SpeciesReference

902018
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Succinate_C4H4O4
type: Species

965925
stoichiometry: 1.0
species: 900352
type: SpeciesReference

910738
is: ENSPTRG00000021741.5
reactant: 996473
name: Putrescine acetyltransferase
product: 996497
is: ENSPTRG00000008699.2
notes: R_PTRCAT1 subsystem: Arginine and Proline Metabolism R_PTRCAT1 equation: [c] : accoa + ptrc --> aprut + coa + h
is: http://identifiers.org/ec-code/2.3.1.57
type: Reaction
reversible: false
fast: false
product: 996509
product: 996485
reactant: 996461

902668
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: trihexosyl ceramide (homo sapiens)_C36H66NO17FULLRCO
type: Species

929988
stoichiometry: 1.0
species: 897492
type: SpeciesReference

975233
stoichiometry: 1.0
species: 881258
type: SpeciesReference

977300
stoichiometry: 1.0
species: 891483
type: SpeciesReference

948832
stoichiometry: 1.0
species: 894224
type: SpeciesReference

995417
stoichiometry: 1.0
species: 892945
type: SpeciesReference

990529
stoichiometry: 1.0
species: 890868
type: SpeciesReference

959893
stoichiometry: 1.0
species: 884073
type: SpeciesReference

920273
stoichiometry: 2.0
species: 898997
type: SpeciesReference

911255
is: ENSPTRG00000007720.4
product: 001353
reactant: 001281
name: Heme oxygenase 1
reactant: 001305
is: http://identifiers.org/ec-code/1.14.99.3
type: Reaction
product: 001377
fast: false
reactant: 001317
is: ENSPTRG00000014298.4
product: 001341
reversible: false
product: 001329
reactant: 001293
notes: R_HOXG subsystem: Heme Degradation R_HOXG equation: [c] : (5) h + (3) nadph + (3) o2 + pheme --> biliverd + co + fe2 + (3) h2o + (3) nadp
product: 001365

993850
stoichiometry: 1.0
species: 890518
type: SpeciesReference

917829
stoichiometry: 1.0
species: 891640
type: SpeciesReference

881535
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: aflatoxin B1_C17H12O6
type: Species

000362
stoichiometry: 1.0
species: 886696
type: SpeciesReference

989073
stoichiometry: 3.0
species: 884391
type: SpeciesReference

905721
stoichiometry: 1.0
species: 880462
type: SpeciesReference

994443
stoichiometry: 2.0
species: 896124
type: SpeciesReference

880003
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: R total_CO2FULLR
type: Species

999964
stoichiometry: 1.0
species: 899542
type: SpeciesReference

987699
stoichiometry: 2.0
species: 896958
type: SpeciesReference

978702
stoichiometry: 1.0
species: 881764
type: SpeciesReference

958224
stoichiometry: 1.0
species: 899650
type: SpeciesReference

907305
fast: false
reactant: 964692
is: ENSPTRG00000003502.4
is: ENSPTRG00000016800.3
reactant: 964680
reactant: 964667
product: 964753
reactant: 964704
is: ENSPTRG00000020739.4
reversible: false
reactant: 964728
notes: R_GLUt6 subsystem: Transport, Extracellular R_GLUt6 equation: glu-L[e] + h[e] + k[c] + (3) na1[e] --> glu-L[c] + h[c] + k[e] + (3) na1[c] R_ASPDt6 subsystem: Transport, Extracellular R_ASPDt6 equation: asp-D[e] + h[e] + k[c] + (3) na1[e] --> asp-D[c] + h[c] + k[e] + (3) na1[c] R_ASPt6 subsystem: Transport, Extracellular R_ASPt6 equation: asp-L[e] + h[e] + k[c] + (3) na1[e] --> asp-L[c] + h[c] + k[e] + (3) na1[c]
reactant: 964716
product: 964740
is: ENSPTRG00000000750.5
product: 964777
product: 964765
is: ENSPTRG00000014294.4
product: 964790
type: Reaction
product: 964802

941576
stoichiometry: 1.0
species: 887582
type: SpeciesReference

900872
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: cis-13-retinal_C20H28O
type: Species

937859
stoichiometry: 4.0
species: 897321
type: SpeciesReference

936688
stoichiometry: 2.0
species: 891483
type: SpeciesReference

983808
stoichiometry: 1.0
species: 886865
type: SpeciesReference

936254
stoichiometry: 2.0
species: 891555
type: SpeciesReference

942728
stoichiometry: 1.0
species: 898442
type: SpeciesReference

894651
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate II biosynthesis, precursor 7_C67H108N5O51SX
type: Species

895556
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: alpha-Linolenoyl-CoA_C39H60N7O17P3S
type: Species

909801
product: 989353
modifier: 989461
product: 989329
reactant: 989244
product: 989437
reactant: 989304
reactant: 989256
reversible: false
modifier: 989497
fast: false
product: 989365
reactant: 989268
notes: R_ARABR subsystem: Pentose and Glucuronate Interconversions R_ARABR equation: [c] : arab-L + h + nadph --> abt + nadp R_LALDO2 subsystem: Pyruvate Metabolism R_LALDO2 equation: [c] : h + mthgxl + nadph --> lald-D + nadp R_ALCD2yf subsystem: Glycolysis/Gluconeogenesis R_ALCD2yf equation: [c] : etoh + nadp --> acald + h + nadph R_ALR3 subsystem: Pyruvate Metabolism R_ALR3 equation: [c] : acetol + h + nadph --> 12ppd-S + nadp R_SBTR subsystem: Fructose and Mannose Metabolism R_SBTR equation: [c] : glc-D + h + nadph --> nadp + sbt-D R_GALOR subsystem: Galactose metabolism R_GALOR equation: [c] : gal + h + nadph <==> galt + nadp R_ALR2 subsystem: Pyruvate Metabolism R_ALR2 equation: [c] : h + mthgxl + nadph --> acetol + nadp R_PPDOy subsystem: Pyruvate Metabolism R_PPDOy equation: [c] : h + lald-D + nadph --> 12ppd-R + nadp
reactant: 989316
is: ENSPTRG00000008742.4
product: 989341
reactant: 989232
reactant: 989220
type: Reaction
product: 989389
is: http://identifiers.org/ec-code/1.1.1.21
product: 989425
product: 989401
modifier: 989473
reactant: 989280
product: 989377
is: http://identifiers.org/ec-code/1.1.1.2
modifier: 989449
product: 989413
modifier: 989485
reactant: 989292

943499
stoichiometry: 3.0
species: 891616
type: SpeciesReference

901174
notes: R_HMGLm subsystem: Cholesterol Metabolism R_HMGLm equation: [m] : hmgcoa --> acac + accoa
reactant: 914522
fast: false
product: 914546
name: hydroxymethylglutaryl-CoA lyase
type: Reaction
reversible: false
is: ENSPTRG00000018299.4
is: http://identifiers.org/ec-code/4.1.3.4
product: 914534

957270
stoichiometry: 2.0
species: 891483
type: SpeciesReference

908838
stoichiometry: 3.0
species: 897347
type: SpeciesReference

943619
stoichiometry: 1.0
species: 882188
type: SpeciesReference

894068
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 16_C157H253N11O124S4X
type: Species

938028
stoichiometry: 4.0
species: 882781
type: SpeciesReference

881137
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Adenine_C5H5N5
type: Species

918277
stoichiometry: 1.0
species: 897347
type: SpeciesReference

892861
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Hypoxanthine_C5H4N4O
type: Species

920418
stoichiometry: 8.0
species: 891616
type: SpeciesReference

900871
is: ENSPTRG00000023606.3
type: Reaction
product: 911902
product: 911890
notes: R_CORE3GTg subsystem: O-Glycan Biosynthesis R_CORE3GTg equation: [g] : Tn_antigen + uacgam --> core3 + h + udp
name: Core 3 beta-GlcNAc-transferase, Golgi apparatus
is: http://identifiers.org/ec-code/2.4.1.147
reactant: 911878
product: 911914
reactant: 911866
reversible: false
fast: false

007676
stoichiometry: 2.0
species: 896825
type: SpeciesReference

989882
stoichiometry: 1.0
species: 894056
type: SpeciesReference

879535
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heptaglutamyl folate (THF)_C49H57N13O24
type: Species

883723
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Choline_C5H14NO
type: Species

941167
stoichiometry: 1.0
species: 887837
type: SpeciesReference

903716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: UDP-D-xylose_C14H20N2O16P2
type: Species

979125
stoichiometry: 1.0
species: 888804
type: SpeciesReference

883130
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Biotinyl-5'-AMP_C20H27N7O9PS
type: Species

972118
stoichiometry: 1.0
species: 894020
type: SpeciesReference

885635
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Cytidine_C9H13N3O5
type: Species

884258
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: CMP-N-acetylneuraminate_C20H29N4O16P
type: Species

985625
stoichiometry: 2.0
species: 879595
type: SpeciesReference

886985
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: N,N-Dimethylglycine_C4H9NO2
type: Species

958393
stoichiometry: 1.0
species: 897900
type: SpeciesReference

901066
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: PA6_C90H145N6O65X
type: Species

961053
stoichiometry: 1.0
species: 903488
type: SpeciesReference

913930
stoichiometry: 1.0
species: 900897
type: SpeciesReference

963831
stoichiometry: 1.0
species: 891640
type: SpeciesReference

980258
stoichiometry: 1.0
species: 888587
type: SpeciesReference

892753
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: heparan sulfate, precursor 4_C51H76N2O42X
type: Species

890131
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-glucurono-6,3-lactone_C6H8O6
type: Species

997413
stoichiometry: 4.0
species: 891555
type: SpeciesReference

902102
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: triacylglycerol (homo sapiens)_C3H5FULLRCO2FULLR2CO2FULLR3CO2
type: Species

000036
stoichiometry: 1.0
species: 891423
type: SpeciesReference

916224
stoichiometry: 1.0
species: 887351
type: SpeciesReference

988628
stoichiometry: 1.0
species: 900678
type: SpeciesReference

904344
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _7alpha-Hydroxy-5beta-cholestan-3-one_C27H46O2
type: Species

954556
stoichiometry: 1.0
species: 878144
type: SpeciesReference

878595
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _4-Methylzymosterol intermediate 1_C29H46O3
type: Species

921917
stoichiometry: 1.0
species: 891748
type: SpeciesReference

933794
stoichiometry: 1.0
species: 898864
type: SpeciesReference

915283
stoichiometry: 1.0
species: 879679
type: SpeciesReference

002025
stoichiometry: 1.0
species: 893223
type: SpeciesReference

917031
stoichiometry: 1.0
species: 895496
type: SpeciesReference

988917
stoichiometry: 1.0
species: 886106
type: SpeciesReference

003980
stoichiometry: 2.0
species: 894518
type: SpeciesReference

967182
stoichiometry: 1.0
species: 893211
type: SpeciesReference

951247
stoichiometry: 1.0
species: 890746
type: SpeciesReference

952624
stoichiometry: 1.0
species: 888321
type: SpeciesReference

985803
stoichiometry: 1.0
species: 884681
type: SpeciesReference

936352
stoichiometry: 3.0
species: 891616
type: SpeciesReference

937206
stoichiometry: 1.0
species: 890506
type: SpeciesReference

895665
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Lipoamide_C8H15NOS2
type: Species

906519
stoichiometry: 2.0
species: 891591
type: SpeciesReference

966443
stoichiometry: 3.0
species: 881282
type: SpeciesReference

898224
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO
type: Species

902103
product: 921398
reactant: 921301
reactant: 921205
reactant: 921241
is: http://identifiers.org/ec-code/2.3.1.7
product: 921313
notes: R_CSNATp subsystem: Fatty Acid Metabolism R_CSNATp equation: [x] : accoa + crn <==> acrn + coa R_CSNATer subsystem: Fatty Acid Metabolism R_CSNATer equation: [r] : accoa + crn <==> acrn + coa R_CSNAT3x subsystem: Carnitine shuttle R_CSNAT3x equation: [x] : crn + ppcoa <==> coa + pcrn R_CSNAT2m subsystem: Carnitine shuttle R_CSNAT2m equation: [m] : coa + pcrn <==> crn + ppcoa R_CSNAT2x subsystem: Fatty Acid Metabolism R_CSNAT2x equation: [x] : crn + dmnoncoa <==> coa + dmnoncrn R_CSNATm subsystem: Fatty Acid Metabolism R_CSNATm equation: [m] : acrn + coa <==> accoa + crn
product: 921374
product: 921337
reactant: 921265
fast: false
reactant: 921229
product: 921350
product: 921386
reversible: true
reactant: 921253
is: ENSPTRG00000021452.4
reactant: 921217
product: 921410
product: 921362
type: Reaction
product: 921325
reactant: 921289
reactant: 921277

911030
stoichiometry: 2.0
species: 899530
type: SpeciesReference

904345
type: Reaction
reactant: 939631
product: 939667
notes: R_DHCRD1 subsystem: Sphingolipid Metabolism R_DHCRD1 equation: [c] : dhcrm_hs + nadp --> crm_hs + h + nadph R_DHCRD2 subsystem: Sphingolipid Metabolism R_DHCRD2 equation: [c] : dhcrm_hs + fad --> crm_hs + fadh2
is: ENSPTRG00000002023.2
reactant: 939643
reactant: 939655
product: 939703
product: 939679
reversible: false
product: 939691
fast: false

968617
stoichiometry: 1.0
species: 899372
type: SpeciesReference

970685
stoichiometry: 1.0
species: 877480
type: SpeciesReference

877950
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Methyl-2-oxobutanoate_C5H7O3
type: Species

907750
product: 969706
product: 969657
fast: false
product: 969718
reactant: 969559
product: 969608
product: 969644
reversible: false
reactant: 969547
reactant: 969499
reactant: 969583
product: 969682
is: ENSPTRG00000021513.5
reactant: 969535
product: 969694
product: 969632
product: 969620
product: 969669
reactant: 969571
reactant: 969511
reactant: 969523
type: Reaction
product: 969596
notes: R_ABO7g subsystem: Blood Group Biosynthesis R_ABO7g equation: [g] : fucgalacgalfucgalacglcgal14acglcgalgluside_hs + udpacgal --> acgalfucgalacgalfucgalacglcgal14acglcgalgluside_hs + h + udp R_ABO5g subsystem: Blood Group Biosynthesis R_ABO5g equation: [g] : fucgalacgalfuc12gal14acglcgalgluside_hs + udpacgal --> acgalfucgalacgalfuc12gal14acglcgalgluside_hs + h + udp R_ABO4g subsystem: Blood Group Biosynthesis R_ABO4g equation: [g] : fuc12gal14acglcgalgluside_hs + udpacgal --> acgalfuc12gal14acglcgalgluside_hs + h + udp R_ABO2g subsystem: Blood Group Biosynthesis R_ABO2g equation: [g] : fucgalacglcgalgluside_hs + udpgal --> galfucgalacglcgalgluside_hs + h + udp R_ABO8g subsystem: Blood Group Biosynthesis R_ABO8g equation: [g] : fucgalacglcgal14acglcgalgluside_hs + udpgal --> galfucgalacglcgal14acglcgalgluside_hs + h + udp R_ABO6g subsystem: Blood Group Biosynthesis R_ABO6g equation: [g] : fucgalacglcgal14acglcgalgluside_hs + udpacgal --> acgalfucgalacglcgal14acglcgalgluside_hs + h + udp R_ABO9g subsystem: Blood Group Biosynthesis R_ABO9g equation: [g] : fucfucgalacglcgalacglcgal14acglcgalgluside_hs + (2) udpgal --> galgalfucfucgalacglcgalacglcgal14acglcgalgluside_hs + (2) h + (2) udp R_ABO3g subsystem: Blood Group Biosynthesis R_ABO3g equation: [g] : fuc12gal14acglcgalgluside_hs + udpgal --> galfuc12gal14acglcgalgluside_hs + h + udp R_ABO1g subsystem: Blood Group Biosynthesis R_ABO1g equation: [g] : fucgalacglcgalgluside_hs + udpacgal --> acgalfucgalacglcgalgluside_hs + h + udp

911478
stoichiometry: 3.0
species: 885780
type: SpeciesReference

976369
stoichiometry: 1.0
species: 887107
type: SpeciesReference

903718
product: 934421
reactant: 934385
fast: false
is: http://identifiers.org/ec-code/2.8.2.23
name: heparin-glucosamine 3-O-sulfotransferase
product: 934409
is: ENSPTRG00000007616.2
product: 934433
reversible: false
reactant: 934397
is: ENSPTRG00000008789.1
type: Reaction
notes: R_S3T3g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T3g equation: [g] : hs_pre15 + paps --> h + hspg + pap

985050
stoichiometry: 1.0
species: 895725
type: SpeciesReference

898708
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Phenylacetaldehyde_C8H8O
type: Species

876476
constant: true
size: NaN
spatial dimensions: 3.0
type: Compartment

891953
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: trans-Hexadec-2-enoyl carnitine_C23H43NO4
type: Species

977760
stoichiometry: 1.0
species: 898418
type: SpeciesReference

884970
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate B (IdoA2S-GalNAc4S), precursor 4_C45H67N2O42S2X
type: Species

984098
stoichiometry: 1.0
species: 884850
type: SpeciesReference

915379
stoichiometry: 11.0
species: 897321
type: SpeciesReference

914607
stoichiometry: 1.0
species: 891050
type: SpeciesReference

934601
stoichiometry: 1.0
species: 888212
type: SpeciesReference

943053
stoichiometry: 1.0
species: 897467
type: SpeciesReference

931040
stoichiometry: 2.0
species: 886009
type: SpeciesReference

912445
stoichiometry: 4.0
species: 884319
type: SpeciesReference

947110
stoichiometry: 1.0
species: 893151
type: SpeciesReference

992244
stoichiometry: 2.0
species: 903440
type: SpeciesReference

891098
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Guanosine_C10H13N5O5
type: Species

973796
stoichiometry: 1.0
species: 876716
type: SpeciesReference

963903
stoichiometry: 1.0
species: 884632
type: SpeciesReference

957559
stoichiometry: 1.0
species: 894963
type: SpeciesReference

925356
stoichiometry: 1.0
species: 890326
type: SpeciesReference

971311
stoichiometry: 1.0
species: 878313
type: SpeciesReference

973603
stoichiometry: 1.0
species: 887278
type: SpeciesReference

001233
stoichiometry: 2.0
species: 897273
type: SpeciesReference

972505
stoichiometry: 1.0
species: 899166
type: SpeciesReference

901694
reversible: true
product: 917418
is: http://identifiers.org/ec-code/1.1.1.94
reactant: 917382
is: ENSPTRG00000004925.3
reactant: 917394
product: 917406
product: 917430
name: glycerol-3-phosphate dehydrogenase (NAD)
notes: R_G3PD1 subsystem: Glycerophospholipid Metabolism R_G3PD1 equation: [c] : glyc3p + nad <==> dhap + h + nadh
type: Reaction
fast: false

960606
stoichiometry: 1.0
species: 898744
type: SpeciesReference

945266
stoichiometry: 2.0
species: 898056
type: SpeciesReference

888539
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Fe2+_Fe
type: Species

975810
stoichiometry: 2.0
species: 899530
type: SpeciesReference

998369
stoichiometry: 1.0
species: 894008
type: SpeciesReference

906259
product: 957596
modifier: 957729
modifier: 957813
modifier: 957717
reactant: 957379
modifier: 957644
modifier: 957801
product: 957559
reactant: 957367
modifier: 957632
fast: false
is: http://identifiers.org/ec-code/1.2.1.3
product: 957511
product: 957608
reactant: 957330
reactant: 957318
modifier: 957777
reactant: 957355
product: 957523
modifier: 957765
reactant: 957391
product: 957535
modifier: 957753
product: 957499
modifier: 957704
modifier: 957741
is: http://identifiers.org/ec-code/1.2.1.39
modifier: 957668
is: http://identifiers.org/ec-code/1.2.1.5
reactant: 957427
modifier: 957656
is: http://identifiers.org/ec-code/1.2.1.4
is: ENSPTRG00000003977.4
reactant: 957463
product: 957571
reactant: 957415
product: 957620
reactant: 957451
reactant: 957439
product: 957584
product: 957547
type: Reaction
modifier: 957789
reactant: 957403
notes: R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHXMANDACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhmald + h2o + nadp <==> 34dhoxmand + (2) h + nadph R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD19x_LPAREN_P_RPAREN_ subsystem: Phenylalanine metabolism R_ALDD19x_LPAREN_P_RPAREN_ equation: [c] : h2o + nadp + pacald --> (2) h + nadph + pac R_34DHPLACOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_34DHPLACOX_LPAREN_NADP_RPAREN_ equation: [c] : 34dhpac + h2o + nadp <==> 34dhpha + (2) h + nadph R_3MOX4HOXPGALDOX subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX equation: [c] : 3m4hpga + h2o + nad --> 3mox4hoxm + (2) h + nadh R_MACOXO subsystem: Histidine Metabolism R_MACOXO equation: [c] : 3mldz + h2o + nad --> 3mlda + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh R_4HOXPACDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_4HOXPACDOX_LPAREN_NADP_RPAREN_ equation: [c] : 4hoxpacd + h2o + nadp <==> 4hphac + (2) h + nadph R_3M4HDXPAC subsystem: Tyrosine metabolism R_3M4HDXPAC equation: [c] : 3mox4hpac + h2o + nad <==> (2) h + homoval + nadh R_34DHPLACOX subsystem: Tyrosine metabolism R_34DHPLACOX equation: [c] : 34dhpac + h2o + nad --> 34dhpha + (2) h + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ subsystem: Tyrosine metabolism R_3MOX4HOXPGALDOX_LPAREN_NADP_RPAREN_ equation: [c] : 3m4hpga + h2o + nadp <==> 3mox4hoxm + (2) h + nadph R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_ALDD19x subsystem: Phenylalanine metabolism R_ALDD19x equation: [c] : h2o + nad + pacald --> (2) h + nadh + pac R_GCALDD subsy…
modifier: 957692
reversible: false
modifier: 957680
reactant: 957342
product: 957475
product: 957487
is: http://identifiers.org/ec-code/1.2.1.21

974437
stoichiometry: 1.0
species: 898708
type: SpeciesReference

895125
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Leucine_C6H13NO2
type: Species

994007
stoichiometry: 1.0
species: 892449
type: SpeciesReference

984158
stoichiometry: 1.0
species: 883988
type: SpeciesReference

929010
stoichiometry: 1.0
species: 888346
type: SpeciesReference

975666
stoichiometry: 1.0
species: 891640
type: SpeciesReference

983796
stoichiometry: 1.0
species: 904549
type: SpeciesReference

940609
stoichiometry: 1.0
species: 881258
type: SpeciesReference

941748
stoichiometry: 1.0
species: 883531
type: SpeciesReference

971986
stoichiometry: 1.0
species: 894164
type: SpeciesReference

945676
stoichiometry: 1.0
species: 891591
type: SpeciesReference

930881
stoichiometry: 1.0
species: 899335
type: SpeciesReference

916658
stoichiometry: 1.0
species: 902475
type: SpeciesReference

901693
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: sphingomyelin (homo sapiens)_C23H48N2O5PFULLRCO
type: Species

910197
stoichiometry: 1.0
species: 898925
type: SpeciesReference

972903
stoichiometry: 1.0
species: 893828
type: SpeciesReference

988217
stoichiometry: 1.0
species: 896643
type: SpeciesReference

984748
stoichiometry: 1.0
species: 903860
type: SpeciesReference

921217
stoichiometry: 1.0
species: 899142
type: SpeciesReference

944593
stoichiometry: 1.0
species: 896052
type: SpeciesReference

946206
stoichiometry: 2.0
species: 891483
type: SpeciesReference

905500
product: 950725
reactant: 950412
product: 950641
reactant: 950400
product: 950653
fast: false
is: ENSPTRG00000009641.2
reactant: 950580
reactant: 950568
product: 950761
reactant: 950556
product: 950689
product: 950701
reactant: 950496
reactant: 950520
reactant: 950544
reactant: 950484
product: 950737
reactant: 950532
product: 950617
product: 950665
notes: R_DNDPt49m subsystem: Transport, Mitochondrial R_DNDPt49m equation: dadp[m] + dttp[c] --> dadp[c] + dttp[m] R_DNDPt22m subsystem: Transport, Mitochondrial R_DNDPt22m equation: dtdp[c] + dudp[m] --> dtdp[m] + dudp[c] R_DNDPt17m subsystem: Transport, Mitochondrial R_DNDPt17m equation: dcdp[m] + dudp[c] --> dcdp[c] + dudp[m] R_DNDPt11m subsystem: Transport, Mitochondrial R_DNDPt11m equation: dadp[c] + dgdp[m] --> dadp[m] + dgdp[c] R_DNDPt52m subsystem: Transport, Mitochondrial R_DNDPt52m equation: dctp[c] + dudp[m] --> dctp[m] + dudp[c] R_DNDPt2m subsystem: Transport, Mitochondrial R_DNDPt2m equation: atp[m] + datp[c] --> atp[c] + datp[m] R_DNDPt63m subsystem: Transport, Mitochondrial R_DNDPt63m equation: dcdp[m] + dgtp[c] --> dcdp[c] + dgtp[m] R_DNDPt47m subsystem: Transport, Mitochondrial R_DNDPt47m equation: dtdp[m] + dttp[c] --> dtdp[c] + dttp[m] R_DNDPt13m subsystem: Transport, Mitochondrial R_DNDPt13m equation: atp[m] + dadp[c] --> atp[c] + dadp[m] R_DNDPt32m subsystem: Transport, Mitochondrial R_DNDPt32m equation: atp[m] + dgdp[c] --> atp[c] + dgdp[m] R_DNDPt12m subsystem: Transport, Mitochondrial R_DNDPt12m equation: adp[m] + dadp[c] --> adp[c] + dadp[m] R_DNDPt46m subsystem: Transport, Mitochondrial R_DNDPt46m equation: dttp[c] + dudp[m] --> dttp[m] + dudp[c] R_DNDPt28m subsystem: Transport, Mitochondrial R_DNDPt28m equation: dcdp[c] + dgdp[m] --> dcdp[m] + dgdp[c] R_DNDPt60m subsystem: Transport, Mitochondrial R_DNDPt60m equation: dgtp[c] + dudp[m] --> dgtp[m] + dudp[c] R_DNDPt24m subsystem: Transport, Mitochondrial R_DNDPt24m equation: dadp[m] + dtdp[c] --> dadp[c] + dtdp[m] R_DNDPt30m subsystem: Transport, Mitochondrial R_DNDPt30m equation: adp[m] + dcdp[c] --> adp[c] + dcdp[m] R_DNDPt54m subsystem: Transport, Mitochondrial R_DNDPt54m equation: dadp[m] + dctp[c] --> dadp[c] + dctp[m] R_DNDPt29m subsystem: Transport, Mitochondrial R_DNDPt29m equation: dadp[m] + dcdp[c] --> dadp[c] + dcdp[m] R_DNDPt8m subsystem: Transport, Mitochondrial R_DNDPt8m equation: da…
product: 950773
reactant: 950472
product: 950785
reactant: 950460
product: 950713
reactant: 950388
reactant: 950448
product: 950593
type: Reaction
reversible: false
reactant: 950436
product: 950629
reactant: 950424
product: 950677
product: 950605
product: 950749
reactant: 950508

008087
stoichiometry: 1.0
species: 883155
type: SpeciesReference

908109
stoichiometry: 2.0
species: 897273
type: SpeciesReference

944448
stoichiometry: 1.0
species: 896016
type: SpeciesReference

925899
stoichiometry: 18.0
species: 891519
type: SpeciesReference

930773
stoichiometry: 1.0
species: 883082
type: SpeciesReference

954991
stoichiometry: 1.0
species: 881282
type: SpeciesReference

912203
stoichiometry: 1.0
species: 887946
type: SpeciesReference

899506
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: phytanyl coa_C41H70N7O17P3S
type: Species

877032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _1-Pyrroline-5-carboxylate_C5H6NO2
type: Species

901390
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Selenophosphate_H2O3PSe
type: Species

935168
stoichiometry: 20.0
species: 891591
type: SpeciesReference

001857
stoichiometry: 1.0
species: 902932
type: SpeciesReference

923424
stoichiometry: 1.0
species: 877468
type: SpeciesReference

926452
stoichiometry: 1.0
species: 877914
type: SpeciesReference

947339
stoichiometry: 1.0
species: 884427
type: SpeciesReference

934123
stoichiometry: 2.0
species: 891591
type: SpeciesReference

887156
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Dolichol diphosphate, human uterine homolog_C1025H1670O70P20
type: Species

877348
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

976619
stoichiometry: 3.0
species: 904006
type: SpeciesReference

959605
stoichiometry: 1.0
species: 901789
type: SpeciesReference

958913
stoichiometry: 1.0
species: 893406
type: SpeciesReference

958054
stoichiometry: 1.0
species: 895000
type: SpeciesReference

928492
stoichiometry: 1.0
species: 888840
type: SpeciesReference

956292
stoichiometry: 1.0
species: 899662
type: SpeciesReference

975979
stoichiometry: 1.0
species: 890674
type: SpeciesReference

888878
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Fucose 1-phosphate_C6H11O8P
type: Species

893574
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: keratan sulfate I, degradation product 1_C241H383N17O209S12X
type: Species

907315
stoichiometry: 1.0
species: 885356
type: SpeciesReference

970034
stoichiometry: 1.0
species: 891640
type: SpeciesReference

965318
stoichiometry: 1.0
species: 896257
type: SpeciesReference

923351
stoichiometry: 1.0
species: 876837
type: SpeciesReference

942945
stoichiometry: 1.0
species: 891218
type: SpeciesReference

995975
stoichiometry: 6.0
species: 891531
type: SpeciesReference

990305
stoichiometry: 1.0
species: 894032
type: SpeciesReference

938933
stoichiometry: 1.0
species: 891591
type: SpeciesReference

961270
stoichiometry: 1.0
species: 888878
type: SpeciesReference

918772
stoichiometry: 1.0
species: 900727
type: SpeciesReference

891266
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Reduced glutathione_C10H16N3O6S
type: Species

007894
stoichiometry: 1.0
species: 897492
type: SpeciesReference

997861
stoichiometry: 1.0
species: 890264
type: SpeciesReference

984352
stoichiometry: 1.0
species: 891531
type: SpeciesReference

961799
stoichiometry: 1.0
species: 896813
type: SpeciesReference

902884
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Thymidine_C10H14N2O5
type: Species

004521
stoichiometry: 1.0
species: 895024
type: SpeciesReference

879967
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: R total 3 Coenzyme A_CO2FULLR3C21H31N7O15P3S
type: Species

915066
stoichiometry: 1.0
species: 893418
type: SpeciesReference

907857
stoichiometry: 1.0
species: 882553
type: SpeciesReference

MODEL1008120000
species: 878457
species: 899178
species: 887375
species: 903149
species: 892437
species: 885007
reaction: 909405
species: 888780
species: 897552
species: 887205
reaction: 911363
species: 885490
species: 890228
species: 892595
species: 887181
species: 900848
species: 898563
species: 883928
species: 895653
reaction: 908126
reaction: 899871
species: 882745
species: 904645
species: 892220
reaction: 903526
reaction: 903441
species: 881885
species: 893671
species: 894056
species: 882998
species: 881813
reaction: 900413
species: 894140
species: 881378
species: 901886
species: 890083
reaction: 905560
species: 897285
species: 891796
species: 891411
species: 891724
species: 901970
species: 887983
species: 901354
reaction: 905921
species: 904368
species: 899638
species: 880511
species: 891880
reaction: 909069
species: 878655
species: 879583
species: 884355
species: 893394
reaction: 900112
species: 879535
reaction: 911423
species: 877674
reaction: 910630
reaction: 909993
species: 893018
species: 888115
species: 900099
reaction: 905536
reaction: 910894
species: 891495
reaction: 909429
reaction: 908852
species: 880595
species: 887788
reaction: 911963
reaction: 902969
reaction: 903490
species: 901169
species: 879234
species: 902463
species: 880219
species: 899372
reaction: 909969
reaction: 910246

895338
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: lignoceryl carnitine_C31H61NO4
type: Species

892473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: heparan sulfate, degradation product 21_C37H55NO38S2
type: Species

010272
stoichiometry: 2.0
species: 882781
type: SpeciesReference

991905
stoichiometry: 1.0
species: 882176
type: SpeciesReference

999212
stoichiometry: 1.0
species: 894939
type: SpeciesReference

905728
product: 952672
is: http://identifiers.org/ec-code/3.1.3.11
is: ENSPTRG00000021136.2
fast: false
reactant: 952624
product: 952660
reactant: 952648
reactant: 952636
notes: R_FBP26 subsystem: Fructose and Mannose Metabolism R_FBP26 equation: [c] : f26bp + h2o --> f6p + pi R_FBP subsystem: Glycolysis/Gluconeogenesis R_FBP equation: [c] : fdp + h2o --> f6p + pi
is: ENSPTRG00000021138.2
is: http://identifiers.org/ec-code/3.1.3.46
type: Reaction
reversible: false

909663
stoichiometry: 2.0
species: 882176
type: SpeciesReference

916743
stoichiometry: 1.0
species: 901826
type: SpeciesReference

933249
stoichiometry: 1.0
species: 879655
type: SpeciesReference

962898
stoichiometry: 1.0
species: 889430
type: SpeciesReference

880438
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Acetaldehyde_C2H4O
type: Species

935988
stoichiometry: 4.0
species: 903488
type: SpeciesReference

902883
is: ENSPTRG00000006584.2
reactant: 927901
is: http://identifiers.org/ec-code/2.3.1.50
notes: R_SERPT subsystem: Sphingolipid Metabolism R_SERPT equation: [c] : h + pmtcoa + ser-L --> 3dsphgn + co2 + coa
fast: false
is: ENSPTRG00000021103.4
reactant: 927877
reversible: false
product: 927913
type: Reaction
name: serine C-palmitoyltransferase
product: 927937
product: 927925
reactant: 927889

979341
stoichiometry: 1.0
species: 902138
type: SpeciesReference

936036
stoichiometry: 1.0
species: 892741
type: SpeciesReference

914934
stoichiometry: 2.0
species: 890095
type: SpeciesReference

947038
stoichiometry: 8.0
species: 891483
type: SpeciesReference

921771
stoichiometry: 1.0
species: 901561
type: SpeciesReference

960907
stoichiometry: 1.0
species: 890167
type: SpeciesReference

972589
stoichiometry: 1.0
species: 900629
type: SpeciesReference

936109
stoichiometry: 2.0
species: 882042
type: SpeciesReference

907858
reactant: 971003
product: 971030
reactant: 970990
reactant: 971016
product: 971056
reversible: true
fast: false
notes: R_UDPGALtg subsystem: Transport, Golgi Apparatus R_UDPGALtg equation: udpgal[c] + ump[g] <==> udpgal[g] + ump[c] R_UGALNACtg subsystem: Transport, Golgi Apparatus R_UGALNACtg equation: udpacgal[c] + ump[g] <==> udpacgal[g] + ump[c]
type: Reaction
is: ENSPTRG00000021874.3
product: 971043

002883
stoichiometry: 1.0
species: 902451
type: SpeciesReference

968352
stoichiometry: 1.0
species: 898032
type: SpeciesReference

940476
stoichiometry: 1.0
species: 902824
type: SpeciesReference

893271
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Inosine_C10H12N4O5
type: Species

982434
stoichiometry: 1.0
species: 888176
type: SpeciesReference

967243
stoichiometry: 25.0
species: 891640
type: SpeciesReference

886757
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dIDP_C10H11N4O10P2
type: Species

963152
stoichiometry: 1.0
species: 888285
type: SpeciesReference

881354
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: ADPribose 2'-phosphate_C15H20N5O17P3
type: Species

953460
stoichiometry: 1.0
species: 897055
type: SpeciesReference

909777
reactant: 989073
is: ENSPTRG00000013424.5
product: 989183
notes: R_ACS2 subsystem: Propanoate Metabolism R_ACS2 equation: [c] : atp + coa + ppa --> amp + ppcoa + ppi R_ACCOAL subsystem: Propanoate Metabolism R_ACCOAL equation: [c] : atp + coa + ppa --> adp + pi + ppcoa R_ACS subsystem: Glycolysis/Gluconeogenesis R_ACS equation: [c] : ac + atp + coa --> accoa + amp + ppi
product: 989170
product: 989122
product: 989146
reactant: 989085
is: http://identifiers.org/ec-code/6.2.1.13
product: 989158
reactant: 989109
fast: false
reversible: false
is: http://identifiers.org/ec-code/6.2.1.1
product: 989134
reactant: 989097
type: Reaction

904128
product: 937328
product: 937292
product: 937218
product: 937304
reactant: 937073
reactant: 937169
product: 937268
type: Reaction
reactant: 937061
reactant: 937109
product: 937230
reactant: 937157
reversible: false
is: ENSPTRG00000004858.4
product: 937280
product: 937243
reactant: 937145
reactant: 937182
product: 937256
product: 937316
product: 937194
reactant: 937097
reactant: 937133
product: 937206
reactant: 937048
reactant: 937085
notes: R_LEUt4 subsystem: Transport, Extracellular R_LEUt4 equation: leu-L[e] + na1[e] --> leu-L[c] + na1[c] R_SERt4 subsystem: Transport, Extracellular R_SERt4 equation: na1[e] + ser-L[e] --> na1[c] + ser-L[c] R_ALAt4 subsystem: Transport, Extracellular R_ALAt4 equation: ala-L[e] + na1[e] --> ala-L[c] + na1[c] R_PROt4 subsystem: Transport, Extracellular R_PROt4 equation: na1[e] + pro-L[e] --> na1[c] + pro-L[c] R_ASNt4 subsystem: Transport, Extracellular R_ASNt4 equation: asn-L[e] + na1[e] --> asn-L[c] + na1[c] R_ARGtiDF subsystem: Transport, Extracellular R_ARGtiDF equation: arg-L[e] --> arg-L[c] R_LYStiDF subsystem: Transport, Extracellular R_LYStiDF equation: lys-L[e] --> lys-L[c] R_HIStiDF subsystem: Transport, Extracellular R_HIStiDF equation: his-L[e] --> his-L[c] R_GLYt4 subsystem: Transport, Extracellular R_GLYt4 equation: gly[e] + na1[e] --> gly[c] + na1[c] R_PHEt4 subsystem: Transport, Extracellular R_PHEt4 equation: na1[e] + phe-L[e] --> na1[c] + phe-L[c] R_GLNt4 subsystem: Transport, Extracellular R_GLNt4 equation: gln-L[e] + na1[e] --> gln-L[c] + na1[c]
reactant: 937121
fast: false

944869
stoichiometry: 1.0
species: 892571
type: SpeciesReference

957837
stoichiometry: 1.0
species: 882697
type: SpeciesReference

882721
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: D-Aspartate_C4H6NO4
type: Species

908997
stoichiometry: 3.0
species: 897261
type: SpeciesReference

993959
stoichiometry: 2.0
species: 891471
type: SpeciesReference

003836
stoichiometry: 1.0
species: 893768
type: SpeciesReference

948414
stoichiometry: 69.0
species: 888418
type: SpeciesReference

880716
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Acetyl-D-glucosamine 1-phosphate_C8H14NO9P
type: Species

996521
stoichiometry: 1.0
species: 891531
type: SpeciesReference

889911
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: GD1beta (homo sapiens)_C66H111N4O38FULLRCO
type: Species

919329
stoichiometry: 1.0
species: 897347
type: SpeciesReference

895883
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C46H77N2O35X
type: Species

905504
stoichiometry: 1.0
species: 897516
type: SpeciesReference

904127
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Vitamin D3_C27H44O
type: Species

882613
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Arginine_C6H15N4O2
type: Species

911038
reactant: 999248
product: 999428
product: 999596
reactant: 999236
product: 999404
reactant: 999175
product: 999488
reactant: 999332
reversible: true
reactant: 999320
fast: false
product: 999512
product: 999392
reactant: 999308
reactant: 999296
product: 999536
product: 999452
product: 999416
product: 999560
reactant: 999356
reactant: 999344
product: 999440
reactant: 999368
product: 999500
is: ENSPTRG00000001116.3
product: 999584
product: 999548
reactant: 999199
product: 999476
product: 999464
product: 999572
reactant: 999260
product: 999380
type: Reaction
reactant: 999187
notes: R_L_DASH_LACtm subsystem: Transport, Mitochondrial R_L_DASH_LACtm equation: h[c] + lac-L[c] <==> h[m] + lac-L[m] R_D_DASH_LACt2 subsystem: Transport, Extracellular R_D_DASH_LACt2 equation: h[e] + lac-D[e] <==> h[c] + lac-D[c] R_PYRt2m subsystem: Transport, Mitochondrial R_PYRt2m equation: h[c] + pyr[c] <==> h[m] + pyr[m] R_ACACt2m subsystem: Transport, Mitochondrial R_ACACt2m equation: acac[c] + h[c] <==> acac[m] + h[m] R_L_DASH_LACt2r subsystem: Transport, Extracellular R_L_DASH_LACt2r equation: h[e] + lac-L[e] <==> h[c] + lac-L[c] R_ACETONEt2m subsystem: Transport, Mitochondrial R_ACETONEt2m equation: acetone[c] + h[c] <==> acetone[m] + h[m] R_ACACt2 subsystem: Transport, Extracellular R_ACACt2 equation: acac[e] + h[e] <==> acac[c] + h[c] R_PYRt2r subsystem: Transport, Extracellular R_PYRt2r equation: h[e] + pyr[e] <==> h[c] + pyr[c] R_ACETONEt2 subsystem: Transport, Extracellular R_ACETONEt2 equation: acetone[e] + h[e] <==> acetone[c] + h[c] R_BUTt2m subsystem: Transport, Mitochondrial R_BUTt2m equation: but[c] + h[c] <==> but[m] + h[m] R_PYRt2p subsystem: D-alanine metabolism R_PYRt2p equation: h[c] + pyr[c] <==> h[x] + pyr[x] R_2HBt2 subsystem: Transport, Extracellular R_2HBt2 equation: _2hb[e] + h[e] <==> 2hb[c] + h[c] R_BTNt2m subsystem: Transport, Mitochondrial R_BTNt2m equation: btn[c] + h[c] <==> btn[m] + h[m] R_BUTt2r subsystem: Transport, Extracellular R_BUTt2r equation: but[e] + h[e] <==> but[c] + h[c] R_BTNt2 subsystem: Transport, Extracellular R_BTNt2 equation: btn[e] + h[e] <==> btn[c] + h[c] R_D_DASH_LACtm subsystem: Transport, Mitochondrial R_D_DASH_LACtm equation: h[c] + lac-D[c] <==> h[m] + lac-D[m]
reactant: 999284
reactant: 999224
product: 999524
reactant: 999272
reactant: 999212

947881
stoichiometry: 1.0
species: 894310
type: SpeciesReference

916007
stoichiometry: 1.0
species: 899530
type: SpeciesReference

984460
stoichiometry: 1.0
species: 891616
type: SpeciesReference

946629
stoichiometry: 1.0
species: 884343
type: SpeciesReference

989726
stoichiometry: 1.0
species: 894116
type: SpeciesReference

969828
stoichiometry: 1.0
species: 897467
type: SpeciesReference

923787
stoichiometry: 1.0
species: 882805
type: SpeciesReference

005767
stoichiometry: 1.0
species: 897528
type: SpeciesReference

979450
stoichiometry: 2.0
species: 891664
type: SpeciesReference

985392
stoichiometry: 1.0
species: 883034
type: SpeciesReference

917261
stoichiometry: 1.0
species: 881801
type: SpeciesReference

906362
stoichiometry: 1.0
species: 891495
type: SpeciesReference

999524
stoichiometry: 1.0
species: 880365
type: SpeciesReference

911697
stoichiometry: 2.0
species: 891086
type: SpeciesReference

962535
stoichiometry: 1.0
species: 885683
type: SpeciesReference

893984
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I_C247H393N17O213S12X
type: Species

896801
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: _1D-myo-Inositol 1,4,5,6-tetrakisphosphate_C6H8O18P4
type: Species

911471
is: ENSPTRG00000009632.1
reactant: 005093
product: 005155
product: 005167
product: 005179
reactant: 005130
reactant: 005106
is: http://identifiers.org/ec-code/3.1.3.5
reactant: 005081
product: 005217
product: 005204
reversible: false
type: Reaction
reactant: 005143
fast: false
product: 005192
reactant: 005118
notes: R_NTD5 subsystem: Pyrimidine Catabolism R_NTD5 equation: [c] : dtmp + h2o --> pi + thymd R_NTD1 subsystem: Pyrimidine Catabolism R_NTD1 equation: [c] : dump + h2o --> duri + pi R_NTD3 subsystem: Pyrimidine Catabolism R_NTD3 equation: [c] : dcmp + h2o --> dcyt + pi R_NTD8 subsystem: Nucleotides R_NTD8 equation: [c] : dgmp + h2o --> dgsn + pi R_NTD12 subsystem: Nucleotides R_NTD12 equation: [c] : dimp + h2o --> din + pi

990989
stoichiometry: 1.0
species: 894927
type: SpeciesReference

959433
stoichiometry: 31.0
species: 891591
type: SpeciesReference

995561
stoichiometry: 2.0
species: 901922
type: SpeciesReference

000796
stoichiometry: 1.0
species: 879246
type: SpeciesReference

993742
stoichiometry: 1.0
species: 889406
type: SpeciesReference

953180
stoichiometry: 1.0
species: 880389
type: SpeciesReference

881246
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Adenosylcobalamin_C72H100CoN18O17P
type: Species

010381
stoichiometry: 1.0
species: 882745
type: SpeciesReference

999103
stoichiometry: 1.0
species: 891158
type: SpeciesReference

950145
stoichiometry: 1.0
species: 903016
type: SpeciesReference

974292
stoichiometry: 1.0
species: 887314
type: SpeciesReference

943342
stoichiometry: 3.0
species: 882066
type: SpeciesReference

002474
stoichiometry: 1.0
species: 885562
type: SpeciesReference

968244
stoichiometry: 1.0
species: 892777
type: SpeciesReference

932295
stoichiometry: 1.0
species: 892655
type: SpeciesReference

878132
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Phosphohydroxypyruvate_C3H2O7P
type: Species

907184
product: 963915
reactant: 963855
product: 963903
reactant: 963867
notes: R_CERT2rt subsystem: Transport, Endoplasmic Reticular R_CERT2rt equation: gluside_hs[c] <==> gluside_hs[r] R_CERT1gt subsystem: Transport, Golgi Apparatus R_CERT1gt equation: crm_hs[c] <==> crm_hs[g] R_CERT2gt subsystem: Transport, Golgi Apparatus R_CERT2gt equation: gluside_hs[c] <==> gluside_hs[g] R_CERT1rt subsystem: Transport, Endoplasmic Reticular R_CERT1rt equation: crm_hs[c] <==> crm_hs[r]
type: Reaction
reversible: true
product: 963879
fast: false
product: 963891
is: ENSPTRG00000016996.4

902775
reversible: false
reactant: 927224
fast: false
product: 927260
reactant: 927212
reactant: 927199
is: ENSPTRG00000009372.4
notes: R_CHLP subsystem: Glycerophospholipid Metabolism R_CHLP equation: [c] : cholp + h2o --> chol + pi R_ETHP subsystem: Glycerophospholipid Metabolism R_ETHP equation: [c] : ethamp + h2o --> etha + pi
type: Reaction
product: 927236
is: http://identifiers.org/ec-code/2.7.7.15
product: 927248

979233
stoichiometry: 1.0
species: 885937
type: SpeciesReference

932102
stoichiometry: 1.0
species: 888672
type: SpeciesReference

901971
reactant: 919982
fast: false
reactant: 919970
reactant: 919957
is: ENSPTRG00000016618.1
reactant: 919945
reversible: false
product: 920018
product: 919994
is: http://identifiers.org/ec-code/3.5.1.26
notes: R_GASNASE2ly subsystem: N-Glycan Degradation R_GASNASE2ly equation: [l] : h2o + n2m2nmasn --> Asn-X-Ser/Thr + n2m2nm R_GASNASE3ly subsystem: Keratan sulfate degradation R_GASNASE3ly equation: [l] : h2o + ksi_deg1 --> Asn-X-Ser/Thr + ksi_deg2 R_GASNASEly subsystem: N-Glycan Degradation R_GASNASEly equation: [l] : h2o + s2l2n2m2masn --> Asn-X-Ser/Thr + s2l2n2m2m
type: Reaction
product: 920006
product: 920030

004630
stoichiometry: 1.0
species: 890131
type: SpeciesReference

941420
stoichiometry: 1.0
species: 896160
type: SpeciesReference

997752
stoichiometry: 10.0
species: 897273
type: SpeciesReference

978919
stoichiometry: 3.0
species: 891567
type: SpeciesReference

910510
product: 994285
name: Phosphatidylserine synthase homo sapiens
reactant: 994273
type: Reaction
product: 994297
is: http://identifiers.org/ec-code/2.7.8.8
is: ENSPTRG00000003117.3
reversible: true
fast: false
reactant: 994261
notes: R_PSSA2_hs subsystem: Glycerophospholipid Metabolism R_PSSA2_hs equation: [c] : pe_hs + ser-L <==> etha + ps_hs

969938
stoichiometry: 1.0
species: 877105
type: SpeciesReference

891375
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Guanidinoacetate_C3H7N3O2
type: Species

910982
stoichiometry: 1.0
species: 896631
type: SpeciesReference

887058
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dimethylallyl diphosphate_C5H9O7P2
type: Species

925789
stoichiometry: 1.0
species: 879414
type: SpeciesReference

964216
stoichiometry: 1.0
species: 891591
type: SpeciesReference

909773
stoichiometry: 3.0
species: 884427
type: SpeciesReference

886600
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dehydroepiandrosterone_C19H28O2
type: Species

931318
stoichiometry: 1.0
species: 883276
type: SpeciesReference

940367
stoichiometry: 1.0
species: 885502
type: SpeciesReference

907749
stoichiometry: 2.0
species: 903004
type: SpeciesReference

890698
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Glycolate_C2H3O3
type: Species

935831
stoichiometry: 1.0
species: 891856
type: SpeciesReference

903608
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: UDPglucose_C15H22N2O17P2
type: Species

911699
reactant: 007470
notes: R_GK1 subsystem: Nucleotides R_GK1 equation: [c] : atp + gmp <==> adp + gdp R_DGK1 subsystem: Nucleotides R_DGK1 equation: [c] : atp + dgmp <==> adp + dgdp
reactant: 007482
reactant: 007494
product: 007506
is: ENSPTRG00000002069.4
type: Reaction
product: 007530
reversible: true
product: 007518
is: http://identifiers.org/ec-code/2.7.4.8
fast: false

901970
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Succinate_C4H4O4
type: Species

904790
product: 943789
product: 943776
reactant: 943752
reversible: true
type: Reaction
fast: false
is: http://identifiers.org/ec-code/5.4.2.2
is: http://identifiers.org/ec-code/5.4.2.8
is: ENSPTRG00000015979.3
reactant: 943764
notes: R_PMANM subsystem: Fructose and Mannose Metabolism R_PMANM equation: [c] : man1p <==> man6p R_PGMT subsystem: Glycolysis/Gluconeogenesis R_PGMT equation: [c] : g1p <==> g6p

933358
stoichiometry: 1.0
species: 882781
type: SpeciesReference

924196
stoichiometry: 1.0
species: 890746
type: SpeciesReference

932403
stoichiometry: 1.0
species: 896946
type: SpeciesReference

935397
stoichiometry: 3.0
species: 887314
type: SpeciesReference

909669
notes: R_NNATn subsystem: NAD Metabolism R_NNATn equation: [n] : atp + h + nicrnt --> dnad + ppi R_NMNATn subsystem: NAD Metabolism R_NMNATn equation: [n] : atp + h + nmn --> nad + ppi
type: Reaction
reversible: false
reactant: 987915
reactant: 987891
product: 987939
is: http://identifiers.org/ec-code/2.7.7.1
fast: false
is: http://identifiers.org/ec-code/2.7.7.18
reactant: 987927
is: ENSPTRG00000000124.3
product: 987964
reactant: 987903
product: 987951

947990
stoichiometry: 1.0
species: 883952
type: SpeciesReference

887351
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dopamine 3-O-sulfate_C8H11NO5S
type: Species

999428
stoichiometry: 1.0
species: 883227
type: SpeciesReference

898092
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: O2_O2
type: Species

895992
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: (alpha-D-mannosyl)6-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)_C58H97N2O45X
type: Species

900594
reactant: 910415
type: Reaction
fast: false
product: 910451
reversible: false
reactant: 910427
product: 910439
notes: R_PPA subsystem: Oxidative Phosphorylation R_PPA equation: [c] : h2o + ppi --> h + (2) pi
name: inorganic diphosphatase
is: ENSPTRG00000002585.5
is: http://identifiers.org/ec-code/3.6.1.1

996630
stoichiometry: 1.0
species: 891640
type: SpeciesReference

960546
stoichiometry: 1.0
species: 898925
type: SpeciesReference

906367
is: ENSPTRG00000009777.3
is: http://identifiers.org/ec-code/1.5.1.2
product: 958705
reactant: 958633
notes: R_P5CRxm subsystem: Arginine and Proline Metabolism R_P5CRxm equation: [m] : 1pyr5c + (2) h + nadh --> nad + pro-L R_P5CRm subsystem: Arginine and Proline Metabolism R_P5CRm equation: [m] : 1pyr5c + (2) h + nadph --> nadp + pro-L
type: Reaction
fast: false
reactant: 958657
product: 958693
reactant: 958645
product: 958681
reversible: false
reactant: 958669

907497
is: http://identifiers.org/ec-code/6.3.2.6
product: 966563
product: 966551
reversible: true
notes: R_AIRCr subsystem: IMP Biosynthesis R_AIRCr equation: [c] : air + co2 <==> 5aizc + h R_PRASCS subsystem: IMP Biosynthesis R_PRASCS equation: [c] : 5aizc + asp-L + atp <==> 25aics + adp + h + pi
product: 966539
product: 966527
reactant: 966479
product: 966515
type: Reaction
reactant: 966467
is: ENSPTRG00000016081.5
reactant: 966491
is: http://identifiers.org/ec-code/4.1.1.21
reactant: 966503
fast: false
reactant: 966455

921663
stoichiometry: 12.0
species: 891591
type: SpeciesReference

924088
stoichiometry: 1.0
species: 895125
type: SpeciesReference

006176
stoichiometry: 1.0
species: 891483
type: SpeciesReference

900449
reversible: false
is: ENSPTRG00000017791.2
name: phosphate transport in/out via three Na+ symporter (irreversible)
is: ENSPTRG00000000445.2
is: ENSPTRG00000017792.3
product: 908985
reactant: 908972
type: Reaction
reactant: 908959
is: ENSPTRG00000017794.4
notes: R_PIt7ir subsystem: Transport, Extracellular R_PIt7ir equation: (3) na1[e] + pi[e] --> (3) na1[c] + pi[c]
fast: false
product: 908997

910512
stoichiometry: 1.0
species: 891616
type: SpeciesReference

991833
stoichiometry: 1.0
species: 891640
type: SpeciesReference

922256
stoichiometry: 1.0
species: 877541
type: SpeciesReference

005875
stoichiometry: 2.0
species: 888780
type: SpeciesReference

908840
reversible: false
product: 981540
product: 981565
type: Reaction
product: 981589
fast: false
reactant: 981516
is: ENSPTRG00000018391.4
reactant: 981479
reactant: 981491
product: 981577
reactant: 981528
product: 981552
reactant: 981504
is: http://identifiers.org/ec-code/3.1.3.5
notes: R_NTD7e subsystem: Nucleotides R_NTD7e equation: [e] : amp + h2o --> adn + pi R_NTD2e subsystem: Nucleotides R_NTD2e equation: [e] : h2o + ump --> pi + uri R_NTD9e subsystem: Nucleotides R_NTD9e equation: [e] : gmp + h2o --> gsn + pi R_NTD4e subsystem: Nucleotides R_NTD4e equation: [e] : cmp + h2o --> cytd + pi

925560
stoichiometry: 2.0
species: 903269
type: SpeciesReference

961162
stoichiometry: 1.0
species: 890252
type: SpeciesReference

970238
stoichiometry: 1.0
species: 896667
type: SpeciesReference

908100
product: 974581
reactant: 974545
reversible: false
reactant: 974509
notes: R_NTD1m subsystem: Nucleotides R_NTD1m equation: [m] : dump + h2o --> duri + pi R_NTD5m subsystem: Nucleotides R_NTD5m equation: [m] : dtmp + h2o --> pi + thymd R_NTD2m subsystem: Nucleotides R_NTD2m equation: [m] : h2o + ump --> pi + uri
type: Reaction
product: 974593
reactant: 974521
is: http://identifiers.org/ec-code/3.1.3.5
fast: false
product: 974569
product: 974557
reactant: 974533
is: ENSPTRG00000030856.2

000687
stoichiometry: 1.0
species: 879294
type: SpeciesReference

907183
stoichiometry: 1.0
species: 885200
type: SpeciesReference

951515
stoichiometry: 3.0
species: 881258
type: SpeciesReference

887910
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: elaidic acid_C18H33O2
type: Species

899226
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Phenethylamine_C8H12N
type: Species

952902
stoichiometry: 1.0
species: 891591
type: SpeciesReference

896172
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: mannosyl-3-(phosphoethanolaminyl-mannosyl)-glucosaminyl-acylphosphatidylinositol (M4A)_C61H116N4O43P4FULLRCO2FULLR2CO2
type: Species

878739
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5,6-Dihydrothymine_C5H8N2O2
type: Species

878024
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Methoxytyramine_C9H14NO2
type: Species

923630
stoichiometry: 1.0
species: 881258
type: SpeciesReference

946738
stoichiometry: 1.0
species: 897516
type: SpeciesReference

944291
stoichiometry: 4.0
species: 897261
type: SpeciesReference

877650
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3-Decaprenyl-4-hydroxy-5-methoxybenzoate_C58H87O4
type: Species

998573
stoichiometry: 1.0
species: 894759
type: SpeciesReference

994890
stoichiometry: 1.0
species: 883663
type: SpeciesReference

966142
stoichiometry: 4.0
species: 888575
type: SpeciesReference

998152
stoichiometry: 2.0
species: 891760
type: SpeciesReference

945374
stoichiometry: 1.0
species: 891483
type: SpeciesReference

928384
stoichiometry: 1.0
species: 889514
type: SpeciesReference

992353
stoichiometry: 1.0
species: 891591
type: SpeciesReference

920963
stoichiometry: 1.0
species: 889454
type: SpeciesReference

931197
stoichiometry: 1.0
species: 902451
type: SpeciesReference

899871
reversible: false
is: http://identifiers.org/ec-code/3.3.2.6
fast: false
reactant: 905697
type: Reaction
product: 905709
reactant: 905685
name: Leukotriene A-4 hydrolase
is: ENSPTRG00000005321.3
notes: R_LTA4H subsystem: Eicosanoid Metabolism R_LTA4H equation: [c] : h2o + leuktrA4 --> leuktrB4

980102
stoichiometry: 3.0
species: 891495
type: SpeciesReference

935721
stoichiometry: 1.0
species: 898346
type: SpeciesReference

950906
stoichiometry: 1.0
species: 884802
type: SpeciesReference

927103
stoichiometry: 1.0
species: 891688
type: SpeciesReference

878409
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _4-Hydroxy-2-oxoglutarate_C5H4O6
type: Species

955508
stoichiometry: 1.0
species: 891591
type: SpeciesReference

918530
stoichiometry: 1.0
species: 901814
type: SpeciesReference

996023
stoichiometry: 1.0
species: 889334
type: SpeciesReference

949497
stoichiometry: 1.0
species: 898672
type: SpeciesReference

897104
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Myristoyl-ACP (n-C14:0ACP)_C25H47N2O8PRS
type: Species

975510
stoichiometry: 1.0
species: 899807
type: SpeciesReference

892317
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Hydroxypyruvate_C3H3O4
type: Species

877504
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4
type: Species

888647
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Folate_C19H18N7O6
type: Species

955665
stoichiometry: 1.0
species: 900038
type: SpeciesReference

907495
stoichiometry: 2.0
species: 886009
type: SpeciesReference

976765
stoichiometry: 3.0
species: 903970
type: SpeciesReference

894493
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate II (core 2-linked), degradation product 6_C44H72N4O33SX
type: Species

932838
stoichiometry: 1.0
species: 891591
type: SpeciesReference

962646
stoichiometry: 1.0
species: 886853
type: SpeciesReference

905945
reactant: 954143
reactant: 954119
fast: false
reactant: 954131
product: 954167
product: 954179
product: 954191
reversible: false
is: ENSPTRG00000002658.2
is: http://identifiers.org/ec-code/2.1.1.6
product: 954155
type: Reaction
notes: R_SALMCOM2 subsystem: Tyrosine metabolism R_SALMCOM2 equation: [c] : adrnl + amet --> ahcys + h + mepi R_SALMCOM subsystem: Tyrosine metabolism R_SALMCOM equation: [c] : amet + nrpphr --> ahcys + h + normete-L

966721
stoichiometry: 1.0
species: 900703
type: SpeciesReference

912553
stoichiometry: 1.0
species: 894939
type: SpeciesReference

905656
product: 952153
notes: R_MMCDm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDm equation: [m] : h + mmcoa-S --> co2 + ppcoa R_MMCDp subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCDp equation: [x] : h + mmcoa-S --> co2 + ppcoa R_MMCD subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMCD equation: [c] : h + mmcoa-S --> co2 + ppcoa R_MCDp subsystem: Fatty Acid Metabolism R_MCDp equation: [x] : h + malcoa --> accoa + co2 R_MCD subsystem: Fatty Acid Metabolism R_MCD equation: [c] : h + malcoa --> accoa + co2 R_MCDm subsystem: Fatty Acid Metabolism R_MCDm equation: [m] : h + malcoa --> accoa + co2
product: 952225
type: Reaction
reactant: 952043
product: 952177
reactant: 952092
product: 952140
reactant: 952031
is: http://identifiers.org/ec-code/4.1.1.9
is: http://identifiers.org/ec-code/4.1.1.41
reactant: 952128
reversible: false
product: 952213
reactant: 952116
reactant: 952080
product: 952165
reactant: 952104
reactant: 952068
fast: false
product: 952237
product: 952201
reactant: 952056
is: ENSPTRG00000008403.3
product: 952189

941857
stoichiometry: 1.0
species: 886069
type: SpeciesReference

950001
stoichiometry: 33.0
species: 884391
type: SpeciesReference

957403
stoichiometry: 2.0
species: 897443
type: SpeciesReference

915489
stoichiometry: 1.0
species: 890686
type: SpeciesReference

948615
stoichiometry: 1.0
species: 882090
type: SpeciesReference

007978
stoichiometry: 1.0
species: 891483
type: SpeciesReference

983687
stoichiometry: 4.0
species: 898032
type: SpeciesReference

900448
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Propenoyl-CoA_C24H34N7O17P3S
type: Species

961366
stoichiometry: 1.0
species: 881198
type: SpeciesReference

954835
stoichiometry: 1.0
species: 890264
type: SpeciesReference

002739
stoichiometry: 1.0
species: 881463
type: SpeciesReference

976490
stoichiometry: 1.0
species: 878192
type: SpeciesReference

888720
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Formimidoyl-L-glutamate_C6H8N2O4
type: Species

900160
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Proline_C5H9NO2
type: Species

992789
stoichiometry: 1.0
species: 878763
type: SpeciesReference

971527
stoichiometry: 1.0
species: 899530
type: SpeciesReference

945966
stoichiometry: 1.0
species: 877516
type: SpeciesReference

916851
stoichiometry: 1.0
species: 881451
type: SpeciesReference

000470
stoichiometry: 1.0
species: 876680
type: SpeciesReference

879258
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: haxglutamyl folate (DHF)_C44H49N12O21
type: Species

877456
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3,4-Dihydroxyphenylethyleneglycol_C8H10O4
type: Species

962742
stoichiometry: 2.0
species: 891531
type: SpeciesReference

887266
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Dolichol phosphate, human liver homolog_C1080H1758O40P10
type: Species

925092
stoichiometry: 1.0
species: 882781
type: SpeciesReference

008196
stoichiometry: 1.0
species: 882310
type: SpeciesReference

959713
stoichiometry: 1.0
species: 883892
type: SpeciesReference

923847
stoichiometry: 1.0
species: 895677
type: SpeciesReference

915126
stoichiometry: 1.0
species: 897636
type: SpeciesReference

001965
stoichiometry: 1.0
species: 900580
type: SpeciesReference

003559
stoichiometry: 1.0
species: 893526
type: SpeciesReference

922891
stoichiometry: 1.0
species: 894140
type: SpeciesReference

981626
stoichiometry: 3.0
species: 891567
type: SpeciesReference

924946
stoichiometry: 1.0
species: 897552
type: SpeciesReference

946314
stoichiometry: 1.0
species: 897309
type: SpeciesReference

949072
stoichiometry: 1.0
species: 894639
type: SpeciesReference

968775
stoichiometry: 1.0
species: 887655
type: SpeciesReference

925464
stoichiometry: 1.0
species: 890155
type: SpeciesReference

926187
stoichiometry: 1.0
species: 879222
type: SpeciesReference

954289
stoichiometry: 1.0
species: 891254
type: SpeciesReference

902776
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Thiamine diphosphate_C12H16N4O7P2S
type: Species

965186
stoichiometry: 2.0
species: 877432
type: SpeciesReference

907159
stoichiometry: 1.0
species: 884814
type: SpeciesReference

934220
stoichiometry: 1.0
species: 900280
type: SpeciesReference

891507
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: H2O_H2O
type: Species

930256
stoichiometry: 2.0
species: 880462
type: SpeciesReference

912880
stoichiometry: 1.0
species: 886624
type: SpeciesReference

885007
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate C (GalNAc6S-GlcA), degradation product 1_C45H68N2O43S2
type: Species

909921
product: 991124
fast: false
reactant: 991075
product: 991160
notes: R_ILETA subsystem: Valine, Leucine, and Isoleucine Metabolism R_ILETA equation: [c] : akg + ile-L <==> 3mop + glu-L R_VALTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_VALTA equation: [c] : akg + val-L <==> 3mob + glu-L R_LEUTA subsystem: Valine, Leucine, and Isoleucine Metabolism R_LEUTA equation: [c] : akg + leu-L <==> 4mop + glu-L
reactant: 991087
is: ENSPTRG00000004772.5
reactant: 991099
is: http://identifiers.org/ec-code/2.6.1.42
is: http://identifiers.org/ec-code/2.6.1.6
reactant: 991112
type: Reaction
product: 991136
reversible: true
product: 991148

965354
stoichiometry: 1.0
species: 891664
type: SpeciesReference

901294
reactant: 915440
product: 915597
is: http://identifiers.org/ec-code/1.2.1.21
is: ENSPTRG00000007113.4
product: 915489
product: 915477
type: Reaction
product: 915537
product: 915573
product: 915549
is: http://identifiers.org/ec-code/1.2.1.4
product: 915585
reversible: false
product: 915513
notes: R_IMACTD subsystem: Histidine Metabolism R_IMACTD equation: [c] : h2o + im4act + nad --> (2) h + im4ac + nadh R_ALDD2y subsystem: Glycolysis/Gluconeogenesis R_ALDD2y equation: [c] : acald + h2o + nadp --> ac + (2) h + nadph R_GLACO subsystem: Ascorbate and Aldarate Metabolism R_GLACO equation: [c] : glac + (2) h2o + nad --> glcr + (3) h + nadh R_ALDD20x subsystem: Tryptophan metabolism R_ALDD20x equation: [c] : h2o + id3acald + nad --> (2) h + ind3ac + nadh R_ALDD2x subsystem: Glycolysis/Gluconeogenesis R_ALDD2x equation: [c] : acald + h2o + nad --> ac + (2) h + nadh R_PYLALDOX subsystem: Limonene and pinene degradation R_PYLALDOX equation: [c] : h2o + nad + pylald --> (2) h + nadh + peracd R_NABTNO subsystem: Arginine and Proline Metabolism R_NABTNO equation: [c] : h2o + n4abutn + nad --> 4aabutn + (2) h + nadh R_5HOXINDACTOX subsystem: Tryptophan metabolism R_5HOXINDACTOX equation: [c] : 5hoxindact + h2o + nad --> 5hoxindoa + (2) h + nadh R_BAMPPALDOX subsystem: beta-Alanine metabolism R_BAMPPALDOX equation: [c] : bamppald + h2o + nad --> ala-B + (2) h + nadh R_LCADi subsystem: Pyruvate Metabolism R_LCADi equation: [c] : h2o + lald-L + nad --> (2) h + lac-L + nadh R_GCALDD subsystem: Glyoxylate and Dicarboxylate Metabolism R_GCALDD equation: [c] : gcald + h2o + nad --> glyclt + (2) h + nadh R_LCADi_D subsystem: Pyruvate Metabolism R_LCADi_D equation: [c] : h2o + lald-D + nad --> (2) h + lac-D + nadh
reactant: 915428
is: http://identifiers.org/ec-code/1.2.1.3
product: 915609
reactant: 915403
reactant: 915379
reactant: 915367
reactant: 915416
product: 915525
product: 915561
reactant: 915391
product: 915621
reactant: 915355
reactant: 915295
reactant: 915343
product: 915501
reactant: 915319
reactant: 915307
product: 915465
reactant: 915452
reactant: 915331
fast: false

942848
stoichiometry: 4.0
species: 898272
type: SpeciesReference

932971
stoichiometry: 4.0
species: 880341
type: SpeciesReference

894261
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 30_C219H350N15O184S9X
type: Species

899868
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: _5-Diphosphoinositol pentakisphosphate_C6H6O27P7
type: Species

919172
stoichiometry: 1.0
species: 901306
type: SpeciesReference

897359
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Nicotinamide adenine dinucleotide_C21H26N7O14P2
type: Species

888212
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Electron transfer flavoprotein oxidized_R
type: Species

904586
product: 942013
reactant: 941686
product: 941929
fast: false
reactant: 941564
notes: R_NDPK9 subsystem: Nucleotides R_NDPK9 equation: [c] : atp + idp <==> adp + itp R_NDPK6n subsystem: Nucleotides R_NDPK6n equation: [n] : atp + dudp <==> adp + dutp R_NDPK8n subsystem: Nucleotides R_NDPK8n equation: [n] : atp + dadp <==> adp + datp R_NDPK3n subsystem: Nucleotides R_NDPK3n equation: [n] : atp + cdp <==> adp + ctp R_NDPK7n subsystem: Nucleotides R_NDPK7n equation: [n] : atp + dcdp <==> adp + dctp R_NDPK8 subsystem: Nucleotides R_NDPK8 equation: [c] : atp + dadp <==> adp + datp R_NDPK2 subsystem: Nucleotides R_NDPK2 equation: [c] : atp + udp <==> adp + utp R_NDPK6 subsystem: Nucleotides R_NDPK6 equation: [c] : atp + dudp <==> adp + dutp R_NDPK2n subsystem: Nucleotides R_NDPK2n equation: [n] : atp + udp <==> adp + utp R_NDPK5 subsystem: Nucleotides R_NDPK5 equation: [c] : atp + dgdp <==> adp + dgtp R_NDPK3 subsystem: Nucleotides R_NDPK3 equation: [c] : atp + cdp <==> adp + ctp R_NDPK4 subsystem: Nucleotides R_NDPK4 equation: [c] : atp + dtdp <==> adp + dttp R_NDPK10n subsystem: Nucleotides R_NDPK10n equation: [n] : atp + didp <==> adp + ditp R_NDPK1 subsystem: Nucleotides R_NDPK1 equation: [c] : atp + gdp <==> adp + gtp R_NDPK7 subsystem: Nucleotides R_NDPK7 equation: [c] : atp + dcdp <==> adp + dctp R_NDPK10 subsystem: Nucleotides R_NDPK10 equation: [c] : atp + didp <==> adp + ditp R_NDPK4n subsystem: Nucleotides R_NDPK4n equation: [n] : atp + dtdp <==> adp + dttp R_NDPK9n subsystem: Nucleotides R_NDPK9n equation: [n] : atp + idp <==> adp + itp R_NDPK5n subsystem: Nucleotides R_NDPK5n equation: [n] : atp + dgdp <==> adp + dgtp R_NDPK1n subsystem: Nucleotides R_NDPK1n equation: [n] : atp + gdp <==> adp + gtp
reactant: 941528
reactant: 941552
product: 941881
product: 941893
reactant: 941612
product: 941796
reactant: 941516
reactant: 941674
reactant: 941600
is: ENSPTRG00000009415.3
product: 941965
reactant: 941638
reactant: 941662
product: 941905
product: 941808
reactant: 941748
reactant: 941540
reactant: 941504
product: 941760
reactant: 941492
product: 941772
product: 941869
reactant: 941650
product: 941941
type: Reaction
reactant: 941735
product: 941833
reactant: 941625
product: 942001
product: 941977
product: 941989
product: 941917
product: 941820
reactant: 941723
product: 941784
reactant: 941711
product: 941953
reactant: 941588
reversible: true
reactant: 941576
is: http://identifiers.org/ec-code/2.7.4.6
reactant: 941698
product: 941845
product: 941857

923327
stoichiometry: 1.0
species: 880280
type: SpeciesReference

929202
stoichiometry: 1.0
species: 880317
type: SpeciesReference

959316
stoichiometry: 1.0
species: 878301
type: SpeciesReference

948976
stoichiometry: 1.0
species: 894104
type: SpeciesReference

969317
stoichiometry: 1.0
species: 885368
type: SpeciesReference

971949
stoichiometry: 1.0
species: 894579
type: SpeciesReference

975208
stoichiometry: 1.0
species: 888744
type: SpeciesReference

995537
stoichiometry: 78.0
species: 888418
type: SpeciesReference

955931
stoichiometry: 1.5
species: 897273
type: SpeciesReference

903836
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Uracil_C4H4N2O2
type: Species

899530
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Phosphate_HO4P
type: Species

884524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Core 6_C16H27N2O10X
type: Species

946086
stoichiometry: 1.0
species: 881668
type: SpeciesReference

940780
stoichiometry: 1.0
species: 897516
type: SpeciesReference

927717
stoichiometry: 1.0
species: 895112
type: SpeciesReference

888974
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
type: Species

930979
stoichiometry: 1.0
species: 895314
type: SpeciesReference

901293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: Se-Adenosylselenomethionine_C15H23N6O5Se
type: Species

990553
stoichiometry: 1.0
species: 890916
type: SpeciesReference

902523
notes: R_ST6GALNAC31 subsystem: Sphingolipid Metabolism R_ST6GALNAC31 equation: [g] : cmpacna + gm1b_hs --> cmp + gd1alpha_hs + h
product: 924824
is: ENSPTRG00000000877.3
fast: false
reversible: false
product: 924848
is: ENSPTRG00000000875.5
reactant: 924812
name: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
type: Reaction
product: 924836
reactant: 924800

937400
stoichiometry: 3.0
species: 897516
type: SpeciesReference

894939
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: D-Lactate_C3H5O3
type: Species

988108
stoichiometry: 3.0
species: 881801
type: SpeciesReference

988796
stoichiometry: 1.0
species: 878301
type: SpeciesReference

904272
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _27-Hydroxycholesterol_C27H46O2
type: Species

912783
stoichiometry: 2.0
species: 891531
type: SpeciesReference

979666
stoichiometry: 1.0
species: 897419
type: SpeciesReference

911138
stoichiometry: 1.0
species: 886624
type: SpeciesReference

971623
stoichiometry: 1.0
species: 882853
type: SpeciesReference

885344
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3_C37H52NO43S4X
type: Species

956064
stoichiometry: 1.0
species: 899359
type: SpeciesReference

933819
stoichiometry: 3.0
species: 891531
type: SpeciesReference

986747
stoichiometry: 8.0
species: 897261
type: SpeciesReference

926633
stoichiometry: 1.0
species: 882781
type: SpeciesReference

998381
stoichiometry: 1.0
species: 888599
type: SpeciesReference

927827
stoichiometry: 1.0
species: 902572
type: SpeciesReference

009465
stoichiometry: 3.0
species: 902836
type: SpeciesReference

993331
stoichiometry: 1.0
species: 898539
type: SpeciesReference

900703
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Pyruvate_C3H3O3
type: Species

889815
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: globoside (homo sapiens)_C44H79N2O22FULLRCO
type: Species

902524
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: tetracosatetraenoyl coenzyme A_C45H70N7O17P3S
type: Species

994031
stoichiometry: 1.0
species: 892353
type: SpeciesReference

919788
stoichiometry: 1.0
species: 898587
type: SpeciesReference

904273
reactant: 939005
product: 939078
product: 939103
reactant: 939053
fast: false
product: 939065
reactant: 939041
type: Reaction
reactant: 939029
product: 939091
is: ENSPTRG00000004749.2
product: 939115
reactant: 939017
reversible: true
notes: R_THYOXt subsystem: Transport, Extracellular R_THYOXt equation: hco3[c] + thyox-L[e] <==> hco3[e] + thyox-L[c] R_ESTRONESt subsystem: Transport, Extracellular R_ESTRONESt equation: estrones[e] + hco3[c] <==> estrones[c] + hco3[e] R_TRIODTHYt subsystem: Transport, Extracellular R_TRIODTHYt equation: hco3[c] + triodthy[e] <==> hco3[e] + triodthy[c] R_ESTRADIOLGLCt subsystem: Transport, Extracellular R_ESTRADIOLGLCt equation: estradiolglc[e] + hco3[c] <==> estradiolglc[c] + hco3[e]

901934
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: stearidonyl coenzyme A_C39H58N7O17P3S
type: Species

966563
stoichiometry: 2.0
species: 891591
type: SpeciesReference

913737
stoichiometry: 2.0
species: 877492
type: SpeciesReference

940091
stoichiometry: 1.0
species: 889839
type: SpeciesReference

976161
stoichiometry: 1.0
species: 879751
type: SpeciesReference

001087
stoichiometry: 1.0
species: 899759
type: SpeciesReference

912409
stoichiometry: 4.0
species: 884391
type: SpeciesReference

944147
stoichiometry: 5.0
species: 885780
type: SpeciesReference

990341
stoichiometry: 1.0
species: 889490
type: SpeciesReference

969974
stoichiometry: 1.0
species: 904452
type: SpeciesReference

976016
stoichiometry: 1.0
species: 890614
type: SpeciesReference

877758
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
type: Species

990402
stoichiometry: 1.0
species: 889526
type: SpeciesReference

967400
stoichiometry: 1.0
species: 883856
type: SpeciesReference

958645
stoichiometry: 1.0
species: 897528
type: SpeciesReference

977748
stoichiometry: 1.0
species: 897948
type: SpeciesReference

905861
product: 953676
reactant: 953664
notes: R_MMMm subsystem: Valine, Leucine, and Isoleucine Metabolism R_MMMm equation: [m] : mmcoa-R <==> succoa
is: ENSPTRG00000018256.4
is: http://identifiers.org/ec-code/5.4.99.2
fast: false
reversible: true
name: methylmalonyl-CoA mutase
type: Reaction

963807
stoichiometry: 1.0
species: 881258
type: SpeciesReference

901935
is: ENSPTRG00000008333.5
reactant: 919752
notes: R_DHORD9 subsystem: Pyrimidine Biosynthesis R_DHORD9 equation: dhor-S[c] + q10[m] --> orot[c] + q10h2[m]
reversible: false
type: Reaction
product: 919788
reactant: 919764
name: dihydoorotic acid dehydrogenase (quinone10)
fast: false
product: 919776

984195
stoichiometry: 2.0
species: 898140
type: SpeciesReference

902246
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: taurochenodeoxycholate_C26H45NO6S
type: Species

979594
stoichiometry: 1.0
species: 879366
type: SpeciesReference

885490
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: CTP_C9H12N3O14P3
type: Species

905975
stoichiometry: 1.0
species: 882384
type: SpeciesReference

942412
stoichiometry: 1.0
species: 901934
type: SpeciesReference

985504
stoichiometry: 1.0
species: 882949
type: SpeciesReference

981304
stoichiometry: 1.0
species: 904501
type: SpeciesReference

952504
stoichiometry: 2.0
species: 891664
type: SpeciesReference

003595
stoichiometry: 1.0
species: 893478
type: SpeciesReference

898732
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: _1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens)_C11H23O4NPFULLRCO2
type: Species

922283
stoichiometry: 1.0
species: 896523
type: SpeciesReference

000893
stoichiometry: 1.0
species: 897516
type: SpeciesReference

951125
stoichiometry: 1.0
species: 890892
type: SpeciesReference

917007
stoichiometry: 1.0
species: 900544
type: SpeciesReference

904489
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _7-alpha,27-Dihydroxycholesterol_C27H46O3
type: Species

009899
stoichiometry: 1.0
species: 890844
type: SpeciesReference

894188
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 25_C199H319N14O163S7X
type: Species

936472
stoichiometry: 1.0
species: 891531
type: SpeciesReference

895785
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol, human liver homolog_C1360H2228N20O270P20
type: Species

991280
stoichiometry: 2.0
species: 891616
type: SpeciesReference

007338
stoichiometry: 2.0
species: 884391
type: SpeciesReference

902247
product: 922662
reactant: 922650
notes: R_TXASr subsystem: Eicosanoid Metabolism R_TXASr equation: [r] : prostgh2 --> txa2
is: ENSPTRG00000019760.4
is: http://identifiers.org/ec-code/5.3.99.5
fast: false
reversible: false
name: Thromboxane-A synthase
type: Reaction

890276
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: L-Glutamine_C5H10N2O3
type: Species

905296
name: fatty acid electroneutral transport
product: 946690
fast: false
notes: R_FATP1t subsystem: Transport, Extracellular R_FATP1t equation: hdca[c] + na1[c] <==> hdca[e] + na1[e]
reactant: 946666
product: 946702
is: ENSPTRG00000021425.5
is: ENSPTRG00000001362.3
reversible: true
type: Reaction
reactant: 946678

974279
stoichiometry: 1.0
species: 877866
type: SpeciesReference

954435
stoichiometry: 1.0
species: 878337
type: SpeciesReference

901574
product: 916260
is: http://identifiers.org/ec-code/2.8.2.1
reactant: 916175
is: ENSPTRG00000023667.3
reversible: false
fast: false
product: 916200
product: 916224
reactant: 916163
product: 916248
reactant: 916139
product: 916212
reactant: 916188
notes: R_DOPASULT subsystem: Tyrosine metabolism R_DOPASULT equation: [c] : dopa + paps --> dopasf + h + pap R_4NPHSULT subsystem: CYP Metabolism R_4NPHSULT equation: [c] : 4nph + paps --> 4nphsf + h + pap R_TYMSULT subsystem: Tyrosine metabolism R_TYMSULT equation: [c] : paps + tym --> h + pap + tymsf R_NRPPHRSULT subsystem: Tyrosine metabolism R_NRPPHRSULT equation: [c] : nrpphr + paps --> h + nrpphrsf + pap
reactant: 916151
product: 916236
type: Reaction

917152
stoichiometry: 1.0
species: 879655
type: SpeciesReference

922879
stoichiometry: 1.0
species: 894383
type: SpeciesReference

879655
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: L-Cysteate_C3H6NO5S
type: Species

958369
stoichiometry: 1.0
species: 887326
type: SpeciesReference

967061
stoichiometry: 1.0
species: 895036
type: SpeciesReference

886504
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: _3alpha,7alpha-Dihydroxy-5beta-cholestanate_C27H45O4
type: Species

880474
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: Acetyl-CoA_C23H34N7O17P3S
type: Species

989280
stoichiometry: 1.0
species: 895000
type: SpeciesReference

980378
stoichiometry: 1.0
species: 903560
type: SpeciesReference

953748
stoichiometry: 1.0
species: 882865
type: SpeciesReference

877492
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3,4-Dihydroxy-L-phenylalanine_C9H11NO4
type: Species

904018
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: vaccenic acid_C18H33O2
type: Species

999757
stoichiometry: 1.0
species: 891591
type: SpeciesReference

911062
notes: R_PFK subsystem: Glycolysis/Gluconeogenesis R_PFK equation: [c] : atp + f6p --> adp + fdp + h
fast: false
is: ENSPTRG00000022972.3
is: ENSPTRG00000002243.5
product: 999757
type: Reaction
product: 999731
reactant: 999706
product: 999744
is: ENSPTRG00000004874.4
is: http://identifiers.org/ec-code/2.7.1.11
reactant: 999719
name: phosphofructokinase
reversible: false

939763
stoichiometry: 1.0
species: 889717
type: SpeciesReference

953314
stoichiometry: 2.0
species: 877130
type: SpeciesReference

923883
stoichiometry: 1.0
species: 887655
type: SpeciesReference

882517
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: arachidonic acid_C20H31O2
type: Species

009175
stoichiometry: 1.0
species: 892994
type: SpeciesReference

988506
stoichiometry: 1.0
species: 886660
type: SpeciesReference

968738
stoichiometry: 1.0
species: 886081
type: SpeciesReference

896728
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _1D-myo-Inositol 1,3,4,5,6-pentakisphosphate_C6H7O21P5
type: Species

961595
stoichiometry: 1.0
species: 902980
type: SpeciesReference

987242
stoichiometry: 3.0
species: 880885
type: SpeciesReference

908559
stoichiometry: 6.0
species: 899578
type: SpeciesReference

951767
stoichiometry: 1.0
species: 879607
type: SpeciesReference

995270
stoichiometry: 1.0
species: 898430
type: SpeciesReference

887582
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dUDP_C9H11N2O11P2
type: Species

901143
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: de-Fuc, reducing GlcNAc removed form of PA6 (w/o peptide linkage)_C76H123N5O57
type: Species

993971
stoichiometry: 1.0
species: 890494
type: SpeciesReference

911134
is: ENSPTRG00000017878.4
type: Reaction
notes: R_GTHPe subsystem: Glutathione Metabolism R_GTHPe equation: [e] : (2) gthrd + h2o2 <==> gthox + (2) h2o
is: ENSPTRG00000017427.4
reactant: 000036
fast: false
is: http://identifiers.org/ec-code/1.11.1.9
name: glutathione peroxidase (e)
product: 000048
product: 000061
reactant: 000024
reversible: true

923991
stoichiometry: 2.0
species: 881258
type: SpeciesReference

962670
stoichiometry: 1.0
species: 893259
type: SpeciesReference

881414
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: adrenic acid_C22H35O2
type: Species

894795
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate II biosynthesis, precursor 3_C55H89N5O38X
type: Species

950376
stoichiometry: 1.0
species: 892281
type: SpeciesReference

905866
stoichiometry: 5.0
species: 884463
type: SpeciesReference

958345
stoichiometry: 2.0
species: 891591
type: SpeciesReference

987554
stoichiometry: 2.0
species: 895919
type: SpeciesReference

007554
stoichiometry: 1.0
species: 891519
type: SpeciesReference

953424
stoichiometry: 2.0
species: 890095
type: SpeciesReference

920538
stoichiometry: 1.0
species: 891591
type: SpeciesReference

895000
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Lactaldehyde_C3H6O2
type: Species

910618
product: 995817
reactant: 995780
fast: false
product: 995841
reactant: 995793
is: ENSPTRG00000009052.4
product: 995829
name: acetyl-CoA carboxylase
notes: R_ACCOAC subsystem: Fatty Acid Metabolism R_ACCOAC equation: [c] : accoa + atp + hco3 --> adp + h + malcoa + pi
reversible: false
type: Reaction
product: 995853
reactant: 995805
is: http://identifiers.org/ec-code/6.4.1.2

903838
is: ENSPTRG00000009098.4
is: http://identifiers.org/ec-code/2.1.1.28
product: 935228
product: 935241
product: 935216
fast: false
notes: R_NORANMT subsystem: Tyrosine metabolism R_NORANMT equation: [c] : amet + nrpphr --> adrnl + ahcys + h
reactant: 935204
name: noradrenaline N-methyltransferase
reactant: 935192
type: Reaction
reversible: false

907894
notes: R_GMAND subsystem: Fructose and Mannose Metabolism R_GMAND equation: [c] : gdpmann --> gdpddman + h2o
reactant: 971467
reversible: false
is: http://identifiers.org/ec-code/4.2.1.47
type: Reaction
is: ENSPTRG00000032578.1
is: ENSPTRG00000031042.1
product: 971479
is: ENSPTRG00000019953.3
fast: false
product: 971491
is: ENSPTRG00000031043.3
name: GDP-D-mannose dehydratase

895411
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: linoelaidic acid (all trans C18:2)_C18H31O2
type: Species

884826
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2_C37H54NO37S2X
type: Species

886865
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dITP_C10H11N4O13P3
type: Species

931872
stoichiometry: 1.0
species: 899530
type: SpeciesReference

994587
stoichiometry: 1.0
species: 896004
type: SpeciesReference

979003
stoichiometry: 2.0
species: 891471
type: SpeciesReference

967690
stoichiometry: 1.0
species: 883820
type: SpeciesReference

964253
stoichiometry: 1.0
species: 886191
type: SpeciesReference

885224
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 5_C45H65N2O48S4X
type: Species

970467
stoichiometry: 2.0
species: 891591
type: SpeciesReference

918398
stoichiometry: 1.0
species: 903317
type: SpeciesReference

978822
stoichiometry: 1.0
species: 891808
type: SpeciesReference

936544
stoichiometry: 1.0
species: 897261
type: SpeciesReference

962970
stoichiometry: 1.0
species: 889538
type: SpeciesReference

904585
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: D-Xylulose 5-phosphate_C5H9O8P
type: Species

982001
stoichiometry: 3.0
species: 891483
type: SpeciesReference

941046
stoichiometry: 1.0
species: 891483
type: SpeciesReference

915163
stoichiometry: 1.0
species: 884319
type: SpeciesReference

907893
stoichiometry: 3.0
species: 891555
type: SpeciesReference

936134
stoichiometry: 1.0
species: 877227
type: SpeciesReference

978193
stoichiometry: 1.0
species: 891953
type: SpeciesReference

927560
stoichiometry: 1.0
species: 897443
type: SpeciesReference

913386
stoichiometry: 1.0
species: 893102
type: SpeciesReference

002037
stoichiometry: 1.0
species: 883579
type: SpeciesReference

946774
stoichiometry: 1.0
species: 885550
type: SpeciesReference

000000
stoichiometry: 1.0
species: 900824
type: SpeciesReference

928620
stoichiometry: 1.0
species: 889094
type: SpeciesReference

999867
stoichiometry: 1.0
species: 882781
type: SpeciesReference

996920
stoichiometry: 1.0
species: 903464
type: SpeciesReference

949387
stoichiometry: 1.0
species: 896655
type: SpeciesReference

915271
stoichiometry: 1.0
species: 890338
type: SpeciesReference

988616
stoichiometry: 1.0
species: 893151
type: SpeciesReference

892741
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: heparan sulfate, precursor 3_C45H69N2O36X
type: Species

947701
stoichiometry: 1.0
species: 894224
type: SpeciesReference

878583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _4 hydroxy tolbutamide_C12H18N2O4S
type: Species

901078
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: de-Fuc form of PA6 (w/o peptide linkage)_C84H136N6O62
type: Species

961065
stoichiometry: 1.0
species: 891616
type: SpeciesReference

913942
stoichiometry: 1.0
species: 900885
type: SpeciesReference

898394
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
type: Species

909501
is: ENSPTRG00000015809.2
is: ENSPTRG00000005107.2
is: ENSPTRG00000009628.3
is: ENSPTRG00000010190.2
is: http://identifiers.org/ec-code/3.6.3.14
is: ENSPTRG00000004342.2
fast: false
is: ENSPTRG00000001099.5
is: ENSPTRG00000009364.4
product: 986034
is: ENSPTRG00000009991.3
notes: R_ATPS4m subsystem: Oxidative Phosphorylation R_ATPS4m equation: adp[m] + (4) h[c] + pi[m] --> atp[m] + (3) h[m] + h2o[m]
reactant: 985998
type: Reaction
is: ENSPTRG00000009320.2
is: ENSPTRG00000005023.4
reactant: 986010
is: ENSPTRG00000012661.3
name: ATP synthase (four protons for one ATP)
product: 986046
reversible: false
reactant: 986022
is: ENSPTRG00000002277.4
product: 986058

884246
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876476
name: CMP_C9H12N3O8P
type: Species

951971
stoichiometry: 1.0
species: 888237
type: SpeciesReference

885623
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Cytidine_C9H13N3O5
type: Species

972106
stoichiometry: 1.0
species: 894176
type: SpeciesReference

940913
stoichiometry: 1.0
species: 885526
type: SpeciesReference

970673
stoichiometry: 1.0
species: 877444
type: SpeciesReference

919486
stoichiometry: 1.0
species: 881282
type: SpeciesReference

987133
stoichiometry: 1.0
species: 896390
type: SpeciesReference

966455
stoichiometry: 1.0
species: 882781
type: SpeciesReference

898236
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: _9-O-Acetylated GT3 (homo sapiens)_C65H106N4O37FULLRCO
type: Species

893538
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 17_C152H245N10O132S7
type: Species

968629
stoichiometry: 1.0
species: 895737
type: SpeciesReference

921627
stoichiometry: 2.0
species: 881885
type: SpeciesReference

954543
stoichiometry: 2.0
species: 891591
type: SpeciesReference

921904
stoichiometry: 1.0
species: 891772
type: SpeciesReference

911066
stoichiometry: 2.0
species: 899795
type: SpeciesReference

990758
stoichiometry: 1.0
species: 882188
type: SpeciesReference

999464
stoichiometry: 1.0
species: 894951
type: SpeciesReference

968581
stoichiometry: 1.0
species: 895749
type: SpeciesReference

950593
stoichiometry: 6.0
species: 887594
type: SpeciesReference

925104
stoichiometry: 1.0
species: 900460
type: SpeciesReference

880583
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: N-Acetyl-L-glutamyl 5-phosphate_C7H9NO8P
type: Species

883143
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Butanoyl-CoA_C25H38N7O17P3S
type: Species

887691
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dUTP_C9H11N2O14P3
type: Species

877963
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: _3-Methyl-2-oxobutanoate_C5H7O3
type: Species

904693
stoichiometry: 1.0
species: 888309
type: SpeciesReference

936242
stoichiometry: 2.0
species: 891664
type: SpeciesReference

978085
stoichiometry: 1.0
species: 895605
type: SpeciesReference

939871
stoichiometry: 1.0
species: 897888
type: SpeciesReference

999976
stoichiometry: 1.0
species: 899530
type: SpeciesReference

937847
stoichiometry: 1.0
species: 880873
type: SpeciesReference

987663
stoichiometry: 1.0
species: 886721
type: SpeciesReference

007663
stoichiometry: 1.0
species: 896764
type: SpeciesReference

902318
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: tetracosahexaenoyl coenzyme A_C45H66N7O17P3S
type: Species

989061
stoichiometry: 1.0
species: 903909
type: SpeciesReference

881523
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Adenylylselenate_C10H12N5O10PSe
type: Species

880039
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: R total_CO2FULLR
type: Species

905757
stoichiometry: 1.0
species: 884391
type: SpeciesReference

931764
stoichiometry: 1.0
species: 879775
type: SpeciesReference

994479
stoichiometry: 3.0
species: 895883
type: SpeciesReference

000374
stoichiometry: 1.0
species: 879258
type: SpeciesReference

920261
stoichiometry: 1.0
species: 892691
type: SpeciesReference

959881
stoichiometry: 1.0
species: 884085
type: SpeciesReference

951404
stoichiometry: 1.0
species: 891591
type: SpeciesReference

904694
notes: R_GALC subsystem: Sphingolipid Metabolism R_GALC equation: [l] : galside_hs + h2o --> crm_hs + gal
name: Galactocerebrosidase
fast: false
reactant: 943186
reversible: false
is: http://identifiers.org/ec-code/3.2.1.46
type: Reaction
reactant: 943198
is: ENSPTRG00000006602.2
product: 943210
product: 943222

941155
stoichiometry: 1.0
species: 899590
type: SpeciesReference

902319
product: 923544
reactant: 923532
notes: R_ACGAMPM subsystem: Aminosugar Metabolism R_ACGAMPM equation: [c] : acgam6p <==> acgam1p
is: ENSPTRG00000018379.4
is: http://identifiers.org/ec-code/5.4.2.3
fast: false
reversible: true
name: phosphoacetylglucosamine mutase
type: Reaction

957113
stoichiometry: 1.0
species: 900484
type: SpeciesReference

883579
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: CDP diacylglycerol (homo sapiens)_C12H17N3O11P2FULLRCO2FULLR2CO2
type: Species

898515
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: naphthalene epoxide_C10H8O
type: Species

918241
stoichiometry: 2.0
species: 881258
type: SpeciesReference

910728
stoichiometry: 1.0
species: 891591
type: SpeciesReference

956497
stoichiometry: 1.0
species: 897984
type: SpeciesReference

004365
stoichiometry: 4.0
species: 903668
type: SpeciesReference

884934
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: chondroitin sulfate B / dermatan sulfate (IdoA2S-GalNAc4S), degradation product 2_C37H54NO41S3
type: Species

006999
stoichiometry: 1.0
species: 904561
type: SpeciesReference

934336
stoichiometry: 1.0
species: 894951
type: SpeciesReference

909309
product: 984592
reactant: 984532
product: 984568
reactant: 984544
reversible: false
product: 984556
is: ENSPTRG00000011241.4
notes: R_PRGNLONESULT subsystem: Steroid Metabolism R_PRGNLONESULT equation: [c] : paps + prgnlone --> h + pap + prgnlones R_CHSTEROLSULT subsystem: Steroid Metabolism R_CHSTEROLSULT equation: [c] : chsterol + paps --> chsterols + h + pap
is: http://identifiers.org/ec-code/2.8.2.2
product: 984580
fast: false
reactant: 984520
type: Reaction

892897
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Hexadecanal_C16H32O
type: Species

962017
stoichiometry: 3.0
species: 884427
type: SpeciesReference

894032
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 13_C143H231N10O111S3X
type: Species

950484
stoichiometry: 6.0
species: 887437
type: SpeciesReference

894687
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate II (core 4-linked), degradation product 1_C78H126N6O64S3X
type: Species

881149
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Adenine_C5H5N5
type: Species

985355
stoichiometry: 1.0
species: 902932
type: SpeciesReference

970576
stoichiometry: 2.0
species: 898708
type: SpeciesReference

895568
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: alpha-linolenyl carnitine_C25H43NO4
type: Species

908404
is: ENSPTRG00000019135.2
reactant: 977287
notes: R_DPGase subsystem: Glycolysis/Gluconeogenesis R_DPGase equation: [c] : 23dpg + h2o --> 3pg + pi R_DPGM subsystem: Glycolysis/Gluconeogenesis R_DPGM equation: [c] : 13dpg <==> 23dpg + h R_PGM subsystem: Glycolysis/Gluconeogenesis R_PGM equation: [c] : 2pg <==> 3pg
modifier: 977361
product: 977313
reactant: 977300
modifier: 977385
modifier: 977373
fast: false
is: ENSPTRG00000019720.2
reversible: false
is: http://identifiers.org/ec-code/3.1.3.13
product: 977325
type: Reaction
modifier: 977337
is: ENSPTRG00000002807.3
is: http://identifiers.org/ec-code/5.4.2.1
modifier: 977349

985088
stoichiometry: 1.0
species: 891616
type: SpeciesReference

876572
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: _10-formyltetrahydrofolate-[Glu](6)_C45H51N12O22
type: Species

996364
stoichiometry: 1.0
species: 899747
type: SpeciesReference

965077
stoichiometry: 1.0
species: 896970
type: SpeciesReference

882913
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Betaine aldehyde_C5H12NO
type: Species

909505
stoichiometry: 1.0
species: 896281
type: SpeciesReference

004209
stoichiometry: 41.0
species: 880764
type: SpeciesReference

982157
stoichiometry: 1.0
species: 896861
type: SpeciesReference

906631
product: 960690
reactant: 960678
notes: R_TYRASE subsystem: Tyrosine metabolism R_TYRASE equation: [c] : 56dihindlcrbxlt --> melanin
is: ENSPTRG00000020774.5
fast: false
reversible: false
name: Tyrosinase
type: Reaction

901827
is: http://identifiers.org/ec-code/6.2.1.3
product: 918494
product: 918566
modifier: 918590
modifier: 918626
modifier: 918614
reactant: 918434
reactant: 918410
modifier: 918602
modifier: 918578
reactant: 918422
reactant: 918398
notes: R_FACOAL180i subsystem: Fatty acid activation R_FACOAL180i equation: [c] : atp + coa + ocdca --> amp + ppi + stcoa R_FACOAL181i subsystem: Fatty acid activation R_FACOAL181i equation: [c] : atp + coa + ocdcea --> amp + odecoa + ppi R_FACOAL150 subsystem: Fatty acid activation R_FACOAL150 equation: [c] : atp + coa + ptdca <==> amp + ppi + ptdcacoa R_FACOAL160i subsystem: Fatty acid activation R_FACOAL160i equation: [c] : atp + coa + hdca --> amp + pmtcoa + ppi R_FACOAL204i subsystem: Fatty acid activation R_FACOAL204i equation: [c] : arachd + atp + coa --> amp + arachdcoa + ppi R_FACOAL170 subsystem: Fatty acid activation R_FACOAL170 equation: [c] : atp + coa + hpdca <==> amp + hpdcacoa + ppi R_FACOAL80i subsystem: Fatty acid activation R_FACOAL80i equation: [c] : atp + coa + octa --> amp + occoa + ppi R_FACOAL140i subsystem: Fatty acid activation R_FACOAL140i equation: [c] : atp + coa + ttdca --> amp + ppi + tdcoa
modifier: 918662
type: Reaction
modifier: 918650
product: 918542
reactant: 918458
product: 918482
product: 918554
reactant: 918470
product: 918518
reactant: 918446
is: ENSPTRG00000012976.3
modifier: 918638
reversible: false
is: http://identifiers.org/ec-code/6.2.1.2
fast: false
product: 918506
product: 918530
reactant: 918386

902679
is: http://identifiers.org/ec-code/2.4.1.101
reactant: 926344
product: 926380
reversible: false
name: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
product: 926368
is: ENSPTRG00000017642.4
notes: R_M13N2Tg subsystem: N-Glycan Biosynthesis R_M13N2Tg equation: [g] : m4masn + uacgam --> h + nm4masn + udp
product: 926356
fast: false
reactant: 926332
type: Reaction

925055
stoichiometry: 1.0
species: 897492
type: SpeciesReference

923218
stoichiometry: 1.0
species: 878132
type: SpeciesReference

932862
stoichiometry: 1.0
species: 902728
type: SpeciesReference

930544
stoichiometry: 1.0
species: 901269
type: SpeciesReference

943887
stoichiometry: 1.0
species: 880256
type: SpeciesReference

000227
stoichiometry: 1.0
species: 882090
type: SpeciesReference

952201
stoichiometry: 1.0
species: 899759
type: SpeciesReference

899759
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Propanoyl-CoA_C24H36N7O17P3S
type: Species

895846
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine_C26H45NO21
type: Species

914197
stoichiometry: 2.0
species: 891591
type: SpeciesReference

948868
stoichiometry: 15.0
species: 899021
type: SpeciesReference

008293
stoichiometry: 1.0
species: 891483
type: SpeciesReference

997594
stoichiometry: 1.0
species: 880051
type: SpeciesReference

910726
name: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
notes: R_GCNTg subsystem: Blood Group Biosynthesis R_GCNTg equation: [g] : galacglcgal14acglcgalgluside_hs + uacgam --> acglcgalacglcgal14acglcgalgluside_hs + h + udp
type: Reaction
reactant: 996400
is: ENSPTRG00000017717.4
reactant: 996413
reversible: false
fast: false
product: 996449
is: http://identifiers.org/ec-code/2.4.1.150
product: 996437
product: 996425

996218
stoichiometry: 1.0
species: 901994
type: SpeciesReference

908828
type: Reaction
product: 981467
fast: false
reversible: false
is: ENSPTRG00000015818.4
product: 981455
product: 981443
reactant: 981431
notes: R_OXAHCOtex subsystem: Transport, Extracellular R_OXAHCOtex equation: (2) hco3[c] + oxa[e] --> (2) hco3[e] + oxa[c] R_SO4HCOtex subsystem: Transport, Extracellular R_SO4HCOtex equation: (2) hco3[c] + so4[e] --> (2) hco3[e] + so4[c]
reactant: 981419
reactant: 981406

991075
stoichiometry: 3.0
species: 881740
type: SpeciesReference

009573
stoichiometry: 1.0
species: 891628
type: SpeciesReference

902006
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Succinate_C4H4O4
type: Species

933929
stoichiometry: 1.0
species: 889839
type: SpeciesReference

951875
stoichiometry: 1.0
species: 891591
type: SpeciesReference

008827
stoichiometry: 2.0
species: 900776
type: SpeciesReference

964520
stoichiometry: 1.0
species: 895000
type: SpeciesReference

888430
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: Flavin adenine dinucleotide reduced_C27H33N9O15P2
type: Species

904164
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: omega hydroxy hexadecanoate (n-C16:0)_C16H31O3
type: Species

919631
stoichiometry: 1.0
species: 890167
type: SpeciesReference

010539
stoichiometry: 2.0
species: 899783
type: SpeciesReference

877866
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _3-Hydroxykynurenamine_C9H13N2O2
type: Species

983108
stoichiometry: 1.0
species: 882139
type: SpeciesReference

001605
stoichiometry: 1.0
species: 893490
type: SpeciesReference

939296
stoichiometry: 1.0
species: 896378
type: SpeciesReference

976910
stoichiometry: 9.0
species: 885888
type: SpeciesReference

908825
stoichiometry: 1.0
species: 900727
type: SpeciesReference

986301
stoichiometry: 1.0
species: 894927
type: SpeciesReference

902007
reversible: false
fast: false
product: 920249
product: 920273
reactant: 920201
product: 920261
reactant: 920213
type: Reaction
reactant: 920225
notes: R_S3T1g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T1g equation: [g] : hs_pre13 + paps --> h + hs_pre14 + pap R_S3T2g subsystem: Chondroitin / heparan sulfate biosynthesis R_S3T2g equation: [g] : hs_pre14 + paps --> h + hs_pre15 + pap
is: ENSPTRG00000018520.2
is: http://identifiers.org/ec-code/2.8.2.23
product: 920237

962307
stoichiometry: 1.0
species: 903161
type: SpeciesReference

982890
stoichiometry: 1.0
species: 891483
type: SpeciesReference

880740
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: N-Acetyl-D-glucosamine_C8H15NO6
type: Species

992885
stoichiometry: 2.0
species: 891664
type: SpeciesReference

993222
stoichiometry: 1.0
species: 901462
type: SpeciesReference

937629
stoichiometry: 3.0
species: 897552
type: SpeciesReference

928517
stoichiometry: 1.0
species: 888938
type: SpeciesReference

009067
stoichiometry: 1.0
species: 877938
type: SpeciesReference

901076
reactant: 913894
product: 913966
notes: R_RDH2a subsystem: Vitamin A Metabolism R_RDH2a equation: [c] : nadp + retinol-9-cis <==> h + nadph + retinal-cis-9 R_RDH1a subsystem: Vitamin A Metabolism R_RDH1a equation: [c] : nadp + retinol <==> h + nadph + retinal
fast: false
type: Reaction
product: 913942
reversible: true
reactant: 913906
is: http://identifiers.org/ec-code/1.1.1.105
is: ENSPTRG00000010455.3
product: 913954
product: 913930
reactant: 913918

901826
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Stearoyl-CoA (n-C18:0CoA)_C39H66N7O17P3S
type: Species

905752
reversible: false
notes: R_GLUTCOADHm subsystem: Tryptophan metabolism R_GLUTCOADHm equation: [m] : fad + glutcoa + h --> b2coa + co2 + fadh2
product: 952780
reactant: 952756
fast: false
reactant: 952768
reactant: 952744
type: Reaction
name: glutaryl-CoA dehydrogenase (mitochondria)
product: 952793
product: 952805
is: http://identifiers.org/ec-code/1.3.99.7
is: ENSPTRG00000010548.3

904165
product: 937485
reactant: 937473
notes: R_5MTHFt subsystem: Transport, Extracellular R_5MTHFt equation: _5mthf[e] <==> 5mthf[c]
is: ENSPTRG00000004027.2
is: ENSPTRG00000004029.3
fast: false
reversible: true
name: _5-Methyltetrahydrofolate transport via receptor binding and protolysis
type: Reaction

897467
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Nicotinamide adenine dinucleotide phosphate_C21H25N7O17P3
type: Species

929552
stoichiometry: 1.0
species: 888539
type: SpeciesReference

928348
stoichiometry: 1.0
species: 886275
type: SpeciesReference

935709
stoichiometry: 1.0
species: 902294
type: SpeciesReference

956702
stoichiometry: 1.0
species: 892293
type: SpeciesReference

979895
stoichiometry: 2.0
species: 891628
type: SpeciesReference

878859
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: _5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate_C9H11N3O9P
type: Species

977530
stoichiometry: 1.0
species: 892801
type: SpeciesReference

965767
stoichiometry: 1.0
species: 888926
type: SpeciesReference

915561
stoichiometry: 1.0
species: 881801
type: SpeciesReference

918518
stoichiometry: 1.0
species: 899626
type: SpeciesReference

899980
reversible: false
product: 906604
type: Reaction
reactant: 906580
product: 906664
product: 906628
reactant: 906568
reactant: 906532
product: 906652
product: 906616
reactant: 906556
product: 906676
product: 906640
reactant: 906592
is: http://identifiers.org/ec-code/3.6.1.15
fast: false
is: http://identifiers.org/ec-code/3.6.1.6
notes: R_NTP3e subsystem: Nucleotides R_NTP3e equation: [e] : gtp + h2o --> gdp + h + pi R_NDP7ex subsystem: Nucleotides R_NDP7ex equation: [e] : h2o + udp --> h + pi + ump R_NDP10ex subsystem: Nucleotides R_NDP10ex equation: [e] : h2o + idp --> h + imp + pi R_NDP3ex subsystem: Nucleotides R_NDP3ex equation: [e] : gdp + h2o --> gmp + h + pi R_NDP8ex subsystem: Nucleotides R_NDP8ex equation: [e] : h2o + utp --> h + pi + udp
reactant: 906544
is: ENSPTRG00000009723.4

921095
stoichiometry: 1.0
species: 884073
type: SpeciesReference

971731
stoichiometry: 1.0
species: 898188
type: SpeciesReference

922395
stoichiometry: 1.0
species: 900220
type: SpeciesReference

948640
stoichiometry: 1.0
species: 899795
type: SpeciesReference

926007
stoichiometry: 1.0
species: 876668
type: SpeciesReference

991713
stoichiometry: 1.0
species: 897648
type: SpeciesReference

965608
stoichiometry: 1.0
species: 878228
type: SpeciesReference

941711
stoichiometry: 1.0
species: 885888
type: SpeciesReference

009319
stoichiometry: 3.0
species: 881897
type: SpeciesReference

932548
stoichiometry: 3.0
species: 891483
type: SpeciesReference

908262
stoichiometry: 1.0
species: 876874
type: SpeciesReference

945532
stoichiometry: 1.0
species: 885925
type: SpeciesReference

948402
stoichiometry: 1.0
species: 899638
type: SpeciesReference

005730
stoichiometry: 1.0
species: 897467
type: SpeciesReference

003138
stoichiometry: 2.0
species: 903004
type: SpeciesReference

960401
stoichiometry: 1.0
species: 890264
type: SpeciesReference

968436
stoichiometry: 1.0
species: 900472
type: SpeciesReference

006031
stoichiometry: 4.0
species: 897273
type: SpeciesReference

906090
notes: R_DESAT24_1 subsystem: Fatty acid elongation R_DESAT24_1 equation: [c] : h + nadh + o2 + tetpent3coa --> (2) h2o + nad + tethex3coa R_DESAT18_8 subsystem: Fatty acid elongation R_DESAT18_8 equation: [c] : h + nadh + o2 + od2coa --> (2) h2o + lneldccoa + nad R_DESAT18_9 subsystem: Fatty acid elongation R_DESAT18_9 equation: [c] : h + lnlccoa + nadh + o2 --> (2) h2o + lnlncgcoa + nad R_DESAT18_6 subsystem: Fatty acid elongation R_DESAT18_6 equation: [c] : h + nadh + o2 + odecoa --> (2) h2o + lneldccoa + nad R_DESAT18_10 subsystem: Fatty acid elongation R_DESAT18_10 equation: [c] : h + lnlncacoa + nadh + o2 --> (2) h2o + nad + strdnccoa R_DESAT18_7 subsystem: Fatty acid elongation R_DESAT18_7 equation: [c] : h + nadh + o2 + vacccoa --> (2) h2o + lneldccoa + nad
reactant: 955112
product: 955256
reactant: 955136
is: http://identifiers.org/ec-code/1.14.19.1
product: 955244
type: Reaction
reactant: 955196
reactant: 955160
product: 955232
product: 955208
reactant: 955100
reversible: false
product: 955220
reactant: 955124
reactant: 955184
reactant: 955172
fast: false
is: ENSPTRG00000003753.4
product: 955268
reactant: 955148

908985
stoichiometry: 1.0
species: 899530
type: SpeciesReference

003848
stoichiometry: 1.0
species: 893562
type: SpeciesReference

995573
stoichiometry: 1.0
species: 900436
type: SpeciesReference

972251
stoichiometry: 1.0
species: 894334
type: SpeciesReference

990977
stoichiometry: 1.0
species: 894963
type: SpeciesReference

999308
stoichiometry: 1.0
species: 894963
type: SpeciesReference

962523
stoichiometry: 2.0
species: 891604
type: SpeciesReference

953896
stoichiometry: 1.0
species: 891591
type: SpeciesReference

898889
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876416
name: _1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens)_C9H15O12P2FULLRCO2FULLR2CO2
type: Species

908261
product: 975906
product: 975930
product: 975918
reactant: 975858
reversible: false
fast: false
notes: R_H6MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_L equation: [r] : (0.1) dolmanp_L + m2emgacpail_hs --> (0.1) dolp_L + h + m3emgacpail_hs R_H8MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_L equation: [r] : (0.1) dolmanp_L + gpi_hs --> (0.1) dolp_L + h + m(em)3gacpail_hs R_H6MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H6MTer_U equation: [r] : (0.1) dolmanp_U + m2emgacpail_hs --> (0.1) dolp_U + h + m3emgacpail_hs R_H7MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_U equation: [r] : (0.1) dolmanp_U + em2emgacpail_hs --> (0.1) dolp_U + h + mem2emgacpail_hs R_H7MTer_L subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H7MTer_L equation: [r] : (0.1) dolmanp_L + em2emgacpail_hs --> (0.1) dolp_L + h + mem2emgacpail_hs R_H8MTer_U subsystem: Glycosylphosphatidylinositol (GPI)-anchor biosynthesis R_H8MTer_U equation: [r] : (0.1) dolmanp_U + gpi_hs --> (0.1) dolp_U + h + m(em)3gacpail_hs
reactant: 975882
reactant: 975846
reactant: 975870
reactant: 975834
product: 975955
product: 975943
product: 975894
type: Reaction
is: ENSPTRG00000015791.2

893996
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876440
name: keratan sulfate I biosynthesis, precursor 10_C129H209N9O98S2X
type: Species

896293
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Malonyl-CoA_C24H33N7O19P3S
type: Species

008935
stoichiometry: 1.0
species: 896716
type: SpeciesReference

906374
stoichiometry: 1.0
species: 895689
type: SpeciesReference

999536
stoichiometry: 1.0
species: 900727
type: SpeciesReference

997898
stoichiometry: 1.0
species: 896631
type: SpeciesReference

893804
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: keratan sulfate I, degradation product 36_C62H103N4O49S1
type: Species

969816
stoichiometry: 1.0
species: 904308
type: SpeciesReference

884391
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: Coenzyme A_C21H32N7O16P3S
type: Species

989738
stoichiometry: 1.0
species: 880656
type: SpeciesReference

903610
type: Reaction
notes: R_N3Tg subsystem: O-Glycan Biosynthesis R_N3Tg equation: [g] : Tn_antigen + udpgal --> T_antigen + h + udp
product: 933539
is: http://identifiers.org/ec-code/2.4.1.122
product: 933552
reactant: 933527
reactant: 933515
name: N-acetylgalactosamine 3-beta-galactosyltransferase, Golgi apparatus
fast: false
is: ENSPTRG00000018925.1
reversible: false
product: 933564

946617
stoichiometry: 1.0
species: 897347
type: SpeciesReference

922722
stoichiometry: 1.0
species: 894176
type: SpeciesReference

923775
stoichiometry: 1.0
species: 881258
type: SpeciesReference

984496
stoichiometry: 1.0
species: 891664
type: SpeciesReference

916959
stoichiometry: 1.0
species: 895436
type: SpeciesReference

949169
stoichiometry: 1.0
species: 894675
type: SpeciesReference

937991
stoichiometry: 1.0
species: 891808
type: SpeciesReference

970358
stoichiometry: 2.0
species: 876680
type: SpeciesReference

999248
stoichiometry: 2.0
species: 900703
type: SpeciesReference

909651
stoichiometry: 2.0
species: 891555
type: SpeciesReference

974171
stoichiometry: 1.0
species: 897888
type: SpeciesReference

961282
stoichiometry: 1.0
species: 881258
type: SpeciesReference

930376
stoichiometry: 1.0
species: 898224
type: SpeciesReference

002353
stoichiometry: 1.0
species: 885550
type: SpeciesReference

961137
stoichiometry: 1.0
species: 880993
type: SpeciesReference

962235
stoichiometry: 1.0
species: 888370
type: SpeciesReference

951659
stoichiometry: 1.0
species: 891531
type: SpeciesReference

890554
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Glycine_C2H5NO2
type: Species

891230
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876428
name: Oxidized glutathione_C20H30N6O12S2
type: Species

902896
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876452
name: Thymidine_C10H14N2O5
type: Species

905140
stoichiometry: 1.0
species: 893127
type: SpeciesReference

915054
stoichiometry: 1.0
species: 901156
type: SpeciesReference

879955
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: R total 3 Coenzyme A_CO2FULLR3C21H31N7O15P3S
type: Species

007882
stoichiometry: 1.0
species: 891555
type: SpeciesReference

984340
stoichiometry: 1.0
species: 899057
type: SpeciesReference

911282
stoichiometry: 2.0
species: 897552
type: SpeciesReference

973025
stoichiometry: 1.0
species: 893876
type: SpeciesReference

881366
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: ADPribose_C15H21N5O14P2
type: Species

993066
stoichiometry: 1.0
species: 887169
type: SpeciesReference

880401
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: Acetoacetate_C4H5O3
type: Species

882733
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876488
name: D-Aspartate_C4H6NO4
type: Species

916731
stoichiometry: 1.0
species: 891965
type: SpeciesReference

957849
stoichiometry: 1.0
species: 897660
type: SpeciesReference

950267
stoichiometry: 1.0
species: 902390
type: SpeciesReference

943222
stoichiometry: 1.0
species: 889478
type: SpeciesReference

886721
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: Dihydrolipolprotein_H2S2X
type: Species

940488
stoichiometry: 1.0
species: 877130
type: SpeciesReference

942632
stoichiometry: 1.0
species: 878060
type: SpeciesReference

979377
stoichiometry: 1.0
species: 887144
type: SpeciesReference

881981
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: lysophosphatidic acid (homo sapiens)_C3H6O5PFULLRCO2
type: Species

963164
stoichiometry: 4.0
species: 891591
type: SpeciesReference

982446
stoichiometry: 1.0
species: 900340
type: SpeciesReference

887473
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876404
name: dTDPglucose_C16H24N2O16P2
type: Species

968364
stoichiometry: 1.0
species: 876752
type: SpeciesReference

902895
product: 927985
reactant: 927949
reversible: false
is: http://identifiers.org/ec-code/3.1.1.31
notes: R_PGL subsystem: Pentose Phosphate Pathway R_PGL equation: [c] : 6pgl + h2o --> 6pgc + h
reactant: 927961
fast: false
is: ENSPTRG00000010677.2
type: Reaction
name: _6-phosphogluconolactonase
product: 927973

967255
stoichiometry: 1.0
species: 890228
type: SpeciesReference

962862
stoichiometry: 1.0
species: 903488
type: SpeciesReference

935976
stoichiometry: 1.0
species: 892813
type: SpeciesReference

921783
stoichiometry: 1.0
species: 901549
type: SpeciesReference

936024
stoichiometry: 1.0
species: 892789
type: SpeciesReference

947026
stoichiometry: 1.0
species: 887314
type: SpeciesReference

004028
stoichiometry: 2.0
species: 893598
type: SpeciesReference

008074
stoichiometry: 1.0
species: 883130
type: SpeciesReference

949905
stoichiometry: 1.0
species: 895290
type: SpeciesReference

003282
stoichiometry: 1.0
species: 885031
type: SpeciesReference

933213
stoichiometry: 1.0
species: 891555
type: SpeciesReference

977325
stoichiometry: 1.0
species: 878120
type: SpeciesReference

955328
stoichiometry: 1.0
species: 904284
type: SpeciesReference

930761
stoichiometry: 1.0
species: 883094
type: SpeciesReference

912215
stoichiometry: 1.0
species: 887971
type: SpeciesReference

992668
stoichiometry: 1.0
species: 883687
type: SpeciesReference

000446
stoichiometry: 1.0
species: 876584
type: SpeciesReference

905536
reversible: false
product: 951138
type: Reaction
product: 951113
product: 951089
reactant: 951077
reactant: 951040
is: http://identifiers.org/ec-code/3.1.4.17
is: ENSPTRG00000018787.4
reactant: 951016
reactant: 951064
product: 951101
fast: false
reactant: 951028
reactant: 951052
product: 951125
notes: R_PDE4g subsystem: Nucleotides R_PDE4g equation: [g] : 35cgmp + h2o --> gmp + h R_PDE1 subsystem: Nucleotides R_PDE1 equation: [c] : camp + h2o --> amp + h R_PDE4 subsystem: Nucleotides R_PDE4 equation: [c] : 35cgmp + h2o --> gmp + h R_PDE1g subsystem: Nucleotides R_PDE1g equation: [g] : camp + h2o --> amp + h
product: 951150

945821
stoichiometry: 2.0
species: 897552
type: SpeciesReference

885901
constant: false
boundary condition: false
has only substance units: false
initial concentration: NaN
initial amount: NaN
in compartment: 876464
name: dCDP_C9H12N3O10P2
type: Species

008609
stoichiometry: 1.0
species: 899045
type: SpeciesReference

985650
stoichiometry: 1.0
species: 889310
type: SpeciesReference

000591
stoichiometry: 1.0
species: 879547
type: SpeciesReference

929772
stoichiometry: 1.0
species: 893406
type: SpeciesReference