UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
bis-molybdopterin mono-guanine dinucleotide
acyl-[acyl-carrier-protein] synthetase (n-C16:0)
Erythronate 4-phosphate (4per) dehydrogenase
phosphoribosylaminoimidazolecarboxamide formyltransferase
glutamine phosphoribosyldiphosphate amidotransferase
phosphoribosylaminoimidazole carboxylase (mutase rxn)
phosphoribosylaminoimidazole carboxylase
phosphopantothenoylcysteine decarboxylase
Dihydroneopterin triphosphate pyrophosphatase
glutamine-fructose-6-phosphate transaminase
acyl-[acyl-carrier-protein] synthetase (n-C12:0)
fatty-acid-CoA thioesterase (dodecanoate)
3-deoxy-manno-octulosonate cytidylyltransferase
3-deoxy-D-manno-octulosonic acid transferase
pyridoxine 5'-phosphate oxidase (anaerboic
acyl-[acyl-carrier-protein] synthetase (n-C16:1)
glutamate-1-semialdehyde aminotransferase
phosphatidylserine (dihexadec-9-enoyl, n-C16:1)
phosphatidylserine (dihexadecanoyl, n-C16:0)
acyl-CoA dehydrogenase (hexadecanoyl-CoA)
D-glucose transport via PEP:Pyr PTS (periplasm)
3,4-Dihydroxy-2-butanone-4-phosphate synthase
3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
3-deoxy -D-manno-octulosonic -acid 8-phosphate synthase
calcium (Ca+2) transport via diffusion (extracellular to periplasm)
two disacharide linked murein units, pentapeptide crosslinked tetrapeptide (A2pm->D-ala) (middle of chain)
iron (III) transport via diffusion (extracellular to periplasm)
bis-molybdopterin guanine dinucleotide synthase
Pimeloyl-[acyl-carrier protein] methyl ester
bis-molybdopterin guanine dinucleotide synthase (single GDP)
acyl-CoA dehydrogenase (tetradecanoyl-CoA)
ribonucleoside-triphosphate reductase (UTP) (flavodoxin)
methylenetetrahydrofolate dehydrogenase (NADP)
Sink needed to allow (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran to leave system
murein crosslinking transpeptidase 1A:(A2pm->D-ala) (periplasm)
ketol-acid reductoisomerase (2,3-dihydroxy-3-methylbutanoate)
ketol-acid reductoisomerase (2-Acetolactate)
3-Deoxy-D-manno-octulosonate 8-phosphate
phosphoribosylaminoimidazolesuccinocarboxamide synthase
phosphoribosylanthranilate isomerase (irreversible)
glyceraldehyde-3-phosphate dehydrogenase
phosphoribosylformylglycinamidine synthase
glucosamine-1-phosphate N-acetyltransferase
2,3,2'3'-Tetrakis(beta-hydroxymyristoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
1-hexadec-9-enoyl-sn-glycerol 3-phosphate
2C-methyl-D-erythritol 2,4 cyclodiphosphate dehydratase
glycerol-3-phosphate dehydrogenase (NADP)
cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)
two linked disacharide pentapeptide murein units (uncrosslinked, middle of chain)
adenosylmethionine-8-amino-7-oxononanoate transaminase
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
UDP-N-acetylmuramoyl-L-alanine synthetase
CO2 transport via diffusion (extracellular to periplasm)
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
glycine hydroxymethyltransferase, reversible
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
UDP-N-acetylenolpyruvoylglucosamine reductase
Glutaryl-[acyl-carrier protein] methyl ester
Enoylglutaryl-[acyl-carrier protein] methyl ester
purine-nucleoside phosphorylase (Adenosine)
Nicotinamide adenine dinucleotide phosphate - reduced
nickel transport via diffusion (extracellular to periplasm)
Nicotinamide adenine dinucleotide - reduced
Nicotinamide adenine dinucleotide phosphate
Sink needed to allow 5'-deoxyribose to leave system
Phosphatidylserine decarboxylase (n-C16:1)
potassium transport via diffusion (extracellular to periplasm)
Phosphatidylserine decarboxylase (n-C16:0)
UDP-3-O-(3-hydroxymyristoyl)glucosamine acyltransferase
3-dehydroquinate dehydratase, irreversible
dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylbutanoate)
cytochrome oxidase bd (menaquinol-8: 2 protons) (periplasm)
phosphoadenylyl-sulfate reductase (thioredoxin)
cytochrome oxidase bd (ubiquinol-8: 2 protons) (periplasm)
glycerol-3-phosphate acyltransferase (C16:1)
glycerol-3-phosphate acyltransferase (C16:0)
phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)
D-glucose transport via diffusion (extracellular to periplasm) irreversible
tryptophan synthase (indoleglycerol phosphate)
3-Oxotetradecanoyl-[acyl-carrier protein]
dihydoorotic acid dehydrogenase (quinone8)
uroporphyrinogen decarboxylase (uroporphyrinogen III)
2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate
2,5-Diamino-6-(ribosylamino)-4-(3H)-pyrimidinone 5'-phosphate
3-Oxo-glutaryl-[acyl-carrier protein] methyl ester
nucleoside-diphosphate kinase (ATP:dTDP)
copper (Cu+2) transport via diffusion (extracellular to periplasm)
fatty-acid-CoA thioesterase (hexadecenoate)
3-Oxo-pimeloyl-[acyl-carrier protein] methyl ester
Smallbone2013 - E.coli metabolic model with modular rate law
Enoylpimeloyl-[acyl-carrier protein] methyl ester
Dihydroxy-acid dehydratase (2,3-dihydroxy-3-methylpentanoate)
2-Dehydro-3-deoxy-D-gluconate 6-phosphate
phosphate transport via diffusion (extracellular to periplasm)
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
ribonucleoside-triphosphate reductase (GTP) (flavodoxin)
Fructose transport via PEP:Pyr PTS (f6p generating) (periplasm)
4,5-dihydroxy-2,3-pentanedione cyclization (spontaneous)
3-phosphoshikimate 1-carboxyvinyltransferase
4-amino-2-methyl-5-phosphomethylpyrimidine synthetase
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
nicotinate-nucleotide diphosphorylase (carboxylating)
diaminohydroxyphosphoribosylaminopryrimidine deaminase (25drapp)
(R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
zinc (Zn+2) transport via diffusion (extracellular to periplasm)
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
3-oxoacyl-[acyl-carrier-protein] synthase (n-C14:0)
2-dehydro-3-deoxy-phosphogluconate aldolase
2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate
D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate
nicotinate-nucleotide adenylyltransferase
coproporphyrinogen oxidase (O2 required)
3-oxoacyl-[acyl-carrier-protein] reductase (n-C14:0)
magnesium (Mg+2) transport via diffusion (extracellular to periplasm)
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran synthesis (spontaneous)
3-Oxo-pimeloyl-[ACP] methyl ester synthase
2-Octaprenylphenol hydroxylase (anaerobic)
Sink needed to allow p-Cresol to leave system
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
molybdate transport via diffusion (extracellular to periplasm)
6-hydroxymethyl-dihydropterin pyrophosphokinase
5-amino-6-(5-phosphoribosylamino)uracil reductase
6-hydroxymethyl-dihydropterin pyrophosphate
5,10-methylenetetrahydrofolate reductase (NADH)
cyclic pyranopterin monophosphate synthase
ATP synthase (four protons for one ATP) (periplasm)
3-methyl-2-oxobutanoate hydroxymethyltransferase
3-Oxo-glutaryl-[ACP] methyl ester dehydratase
3-Hydroxypimeloyl-[acyl-carrier protein] methyl ester
3-Oxo-glutaryl-[ACP] methyl ester reductase
phosphatidylethanolamine (dihexadecanoyl, n-C16:0)
3-Oxo-glutaryl-[ACP] methyl ester synthase
3-Oxo-pimeloyl-[ACP] methyl ester dehydratase
3-Oxo-pimeloyl-[ACP] methyl ester reductase
phosphatidylethanolamine (dihexadec-9enoyl, n-C16:1)
ammonia transport via diffusion (extracellular to periplasm)
Methanol transport via diffusion (extracellular to periplasm)
ribonucleoside-triphosphate reductase (ATP) (flavodoxin)
L-glutamate 5-semialdehyde dehydratase (spontaneous)
3-Hydroxyglutaryl-[acyl-carrier protein] methyl ester
Manganese (Mn+2) transport via diffusion (extracellular to periplasm)
oxygen transport via diffusion (extracellular to periplasm)
Dihydroneopterin monophosphate dephosphorylase
fatty-acid-CoA thioesterase (hexadecanoate)
acetaldehyde dehydrogenase (acetylating)
3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA)
pantetheine-phosphate adenylyltransferase
3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)
acetyl-CoA C-acyltransferase (dodecanoyl-CoA) (r)
acetyl-CoA C-acyltransferase (hexanoyl-CoA) (r)
3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA)
acetyl-CoA C-acyltransferase (butanoyl-CoA) (r)
3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA)
acetyl-CoA C-acyltransferase (decanoyl-CoA) (r)
3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA)
1,2-dihexadecanoyl-sn-glycerol 3-phosphate
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase
1,2-dihexadec-9-enoyl-sn-glycerol 3-phosphate
Enoylpimeloyl-[ACP] methyl ester reductase
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase
Enoylglutaryl-[ACP] methyl ester reductase
chloride (Cl-1) transport via diffusion (extracellular to periplasm)
phospho-L-serine phosphatase (periplasmic)
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
acetyl-CoA C-acyltransferase (tetradecanoyl-CoA) (r)
acetyl-CoA C-acyltransferase (octanoyl-CoA) (r)
3-hydroxyacyl-CoA dehydratase (3-hydroxydodecanoyl-CoA)
2-Oxo-4-methyl-3-carboxypentanoate decarboxylation
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexadecanoyl-CoA)
2-C-methyl-D-erythritol 2,4-cyclodiphosphate
3-hydroxyacyl-CoA dehydratase (3-hydroxyhexanoyl-CoA)
Octaprenyl-hydroxybenzoate decarboxylase
2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate
3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA)
3-hydroxyacyl-CoA dehydratase (3-hydroxydecanoyl-CoA)
aconitase (half-reaction A, Citrate hydro-lyase)
sulfate transport via diffusion (extracellular to periplasm)
1-hexadec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:1)
1-hexadecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:0)
iron (II) transport via diffusion (extracellular to periplasm)
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (dmpp)
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (ipdp)
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
Sink needed to allow S-Adenosyl-4-methylthio-2-oxobutanoate to leave system
[2Fe-1S] desulfurated iron-sulfur cluster
ribonucleoside-triphosphate reductase (CTP) (flavodoxin)
cobalt (Co+2) transport via diffusion (extracellular to periplasm)
aconitase (half-reaction B, Isocitrate hydro-lyase)
3-hydroxyacyl-CoA dehydratase (3-hydroxytetradecanoyl-CoA)
3-hydroxyacyl-CoA dehydratase (3-hydroxyoctanoyl-CoA)
O-Phospho-4-hydroxy-L-threonine:2-oxoglutarate aminotransferase
3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA)
3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA)