COPASI62
reactant: 408302
product: 408314
modifier: 965599
modifier: 965587
modifier: 408326
fast: false
kinetic law: 408338
reversible: false
type: Reaction
name: Peripheral LDLR Synthesis

COPASI6
is version of: CHEBI:22868
constant: false
boundary condition: false
has only substance units: false
initial concentration: 400.0
initial amount: NaN
in compartment: 454202
name: HBS
type: Species

408158
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

408314
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

407726
value: 0.016
name: k1
type: LocalParameter

407306
value: 5.0E-4
name: k8
type: LocalParameter

408518
value: 0.1068
name: k24
type: LocalParameter

COPASI52
modifier: 407774
modifier: 965419
name: Hepatic LDLR Synthesis
product: 407750
reactant: 407738
modifier: 407762
fast: false
type: Reaction
modifier: 965407
kinetic law: 407786
reversible: false

COPASI32
is version of: Q00341
constant: false
boundary condition: false
has only substance units: false
initial concentration: 45.0
initial amount: NaN
in compartment: 454226
name: HDLC
type: Species

454226
is version of: BTO:0000131
constant: true
units: 406729
size: 1.0
spatial dimensions: 3.0
name: Plasma
type: Compartment

407990
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

407066
value: 0.856
name: k1
type: LocalParameter

406789
exponent: 1.0
scale: 0
multipler: 1.0
kind: DIMENSIONLESS
type: SBMLUnit

COPASI28
is: SBO:0000291
constant: true
boundary condition: true
has only substance units: false
initial concentration: 575.16
initial amount: NaN
in compartment: 454214
name: PLDLRsS
type: Species

COPASI14
is: SBO:0000291
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454202
name: HCS
type: Species

COPASI42
name: Bile Salt Synthesis
modifier: 965227
type: Reaction
product: 407090
reversible: false
modifier: 965239
reactant: 407078
kinetic law: 407114
fast: false
modifier: 407102
is version of: GO:0006699

406850
stoichiometry: 1.0
species: COPASI5
type: SpeciesReference

COPASI5
is: SBO:0000291
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454190
name: ICS
type: Species

COPASI63
kinetic law: 408386
modifier: 965611
product: 408374
reactant: 408362
fast: false
reversible: false
name: Peripheral LDL Receptor Degradation
type: Reaction

408098
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

COPASI53
kinetic law: 407834
modifier: 965431
product: 407822
reactant: 407810
fast: false
reversible: false
name: Hepatic LDL Receptor Degradation
type: Reaction

408242
value: 0.00675
name: k20
type: LocalParameter

407150
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

408638
value: 1.5E-5
name: k26
type: LocalParameter

COPASI29
is: SBO:0000291
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454214
name: PLDLRD
type: Species

COPASI33
type: Species
name: LCAT
has part: P04180
constant: false
initial concentration: 100.0
boundary condition: false
initial amount: NaN
has only substance units: false
has part: CHEBI:61995
in compartment: 454226

407978
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

408722
stoichiometry: 1.0
species: COPASI32
type: SpeciesReference

407810
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

COPASI71
reversible: false
name: Reverse Cholesterol Transport
kinetic law: 408878
is version of: GO:0043691
product: 408854
modifier: 408866
type: Reaction
fast: false
modifier: 965779
reactant: 408842
modifier: 965791

408410
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

COPASI15
is version of: CHEBI:17002
constant: false
boundary condition: false
has only substance units: false
initial concentration: 10000.0
initial amount: NaN
in compartment: 454202
name: HCE
type: Species

408194
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

408686
value: 500.0
name: PCSmax
type: LocalParameter

COPASI43
kinetic law: 407174
name: Cholesterol Absorption
reactant: 407138
modifier: 965263
modifier: 965251
type: Reaction
has version: GO:0030299
product: 407150
reversible: false
modifier: 407162
fast: false

408782
stoichiometry: 1.0
species: COPASI32
type: SpeciesReference

COPASI4
is version of: CHEBI:16113
constant: false
boundary condition: false
has only substance units: false
initial concentration: 3150.0
initial amount: NaN
in compartment: 454190
name: IC
type: Species

COPASI64
kinetic law: 408446
name: Peripheral Cholesterol Storage
product: 408422
modifier: 408434
modifier: 965623
fast: false
type: Reaction
reversible: false
reactant: 408410
modifier: 965635

COPASI50
name: Hepatic Nascent HDL Synthesis
kinetic law: 407666
reactant: 407630
fast: false
reversible: false
type: Reaction
modifier: 965383
modifier: 407654
is version of: GO:0042158
product: 407642

408770
value: 0.01
name: k27
type: LocalParameter

407450
value: 500.0
name: HCSmax
type: LocalParameter

407366
value: 2000.0
name: BCRmax
type: LocalParameter

COPASI26
is version of: Q05469
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454226
name: HSL
type: Species

454190
is version of: BTO:0000648
constant: true
units: 406729
size: 1.0
spatial dimensions: 3.0
name: Intestine
type: Compartment

COPASI30
is version of: CHEBI:17002
constant: false
boundary condition: false
has only substance units: false
initial concentration: 9363.0
initial amount: NaN
in compartment: 454214
name: PCE
type: Species

406814
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

407090
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

COPASI44
reactant: 407198
modifier: 407222
modifier: 965275
fast: false
name: Cholesterol Excretion
modifier: 965287
is version of: GO:0033344
product: 407210
kinetic law: 407234
type: Reaction
reversible: false

454214
is version of: FMA:9637
constant: true
units: 406729
size: 1.0
spatial dimensions: 3.0
name: PeripheralTissue
type: Compartment

408830
value: 0.001
name: k28
type: LocalParameter

406777
unit: 406789
name: substance
type: SBMLUnitsDef

408482
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

407078
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

COPASI70
type: Reaction
is version of: GO:0030301
name: CETP Mediated TransferTo LDL
kinetic law: 408818
modifier: 965755
product: 408794
fast: false
modifier: 408806
reversible: false
modifier: 965767
reactant: 408782

COPASI16
constant: false
initial concentration: 100.0
has part: CHEBI:17984
has part: P04180
has only substance units: false
in compartment: 454202
initial amount: NaN
boundary condition: false
type: Species
name: ACAT

COPASI65
name: Release of Stored Peripheral Cholesterol
modifier: 408494
reversible: false
fast: false
modifier: 965647
modifier: 965659
type: Reaction
reactant: 408470
kinetic law: 408506
product: 408482

COPASI3
is version of: CHEBI:16113
constant: true
boundary condition: true
has only substance units: false
initial concentration: 304.0
initial amount: NaN
in compartment: 454178
name: DC
type: Species

408398
value: 0.01
name: k1
type: LocalParameter

COPASI51
kinetic law: 407714
modifier: 965395
product: 407702
reactant: 407690
fast: false
reversible: false
name: VLDL Cholesterol Formation
type: Reaction

408470
stoichiometry: 1.0
species: COPASI30
type: SpeciesReference

COPASI31
is: SBO:0000291
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454214
name: PSS
type: Species

407678
value: 0.005
name: k11
type: LocalParameter

COPASI27
is version of: P01130
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454214
name: PLDLRs
type: Species

407558
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

408182
value: 0.005
name: k1
type: LocalParameter

408698
value: 80342.0
name: PPCt
type: LocalParameter

COPASI45
type: Reaction
product: 407270
modifier: 407282
reactant: 407258
name: Intestinal Nascent HDL Synthesis
kinetic law: 407294
reversible: false
modifier: 965299
fast: false
is version of: GO:0042158

COPASI17
is version of: Q6PIU2
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454202
name: CEH
type: Species

408710
value: 5.0
name: PCSS
type: LocalParameter

408578
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

COPASI56
kinetic law: 408002
modifier: 965479
product: 407990
reactant: 407978
fast: false
reversible: false
name: IDL Cholesterol ReUptake
type: Reaction

454202
is version of: FMA:15815
constant: true
units: 406729
size: 1.0
spatial dimensions: 3.0
name: HepaticTissue
type: Compartment

406729
unit: 406741
name: volume
type: SBMLUnitsDef

408254
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

406765
exponent: 1.0
scale: 0
multipler: 86400.0
kind: SECOND
type: SBMLUnit

407690
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

406802
stoichiometry: 1.0
species: COPASI3
type: SpeciesReference

COPASI66
kinetic law: 408554
modifier: 965671
product: 408542
reactant: 408530
fast: false
reversible: false
name: Peripheral Steroid Production
type: Reaction

COPASI24
is version of: P06858
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454226
name: LPL
type: Species

408134
value: 0.068
name: k18
type: LocalParameter

407330
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

407618
value: 5.998
name: k10
type: LocalParameter

407702
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

407246
value: 5.286E-4
name: k7
type: LocalParameter

COPASI10
is version of: CHEBI:16113
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454238
name: EC
type: Species

407018
value: 4.29
name: k1
type: LocalParameter

COPASI57
name: LDL Cholesterol Formation
fast: false
type: Reaction
product: 408038
kinetic law: 408062
reactant: 408026
modifier: 965503
reversible: false
modifier: 965491
modifier: 408050

408290
value: 5.0E-6
name: k1
type: LocalParameter

407642
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

COPASI67
reversible: false
product: 408602
reactant: 408578
modifier: 965707
modifier: 965695
name: HDL Cholesterol Formation
modifier: 965683
modifier: 408614
reactant: 408590
fast: false
type: Reaction
kinetic law: 408626

407414
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

408662
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

BIOMD0000000434
name: Rate Law for Bile Salt Synthesis
species: COPASI22
species: COPASI8
species: COPASI23
species: COPASI9
function def: COPASI74
reaction: COPASI61
species: COPASI14
units def: 406753
name: Rate Law for LDL Cholesterol Formation
function def: COPASI83
reaction: COPASI52
function def: COPASI76
species: COPASI10
function def: COPASI93
reaction: COPASI64
name: Rate Law for Peripheral Cholesterol Synthesis
name: Rate Law for Cholesterol Absorption
reaction: COPASI55
name: Rate Law for Receptor Dependent Peripheral Uptake
substance units: 406777
compartment: 454178
name: Rate Law for Billary Cholesterol Release
function def: COPASI73
reaction: COPASI67
name: Rate Law for IDL Cholesterol Formation
reaction: COPASI70
name: Rate Law for Release of Stored Cholesterol
compartment: 454238
is version of: GO:0007571
name: McAuley2012 - Whole-body Cholesterol Metabolism
reaction: COPASI46
reaction: COPASI37
function def: COPASI94
name: Rate Law for CETP Mediated Transfer To VLDL
reaction: COPASI41
species: COPASI36
name: Rate Law for Hepatic Cholesterol Storage_1
function def: COPASI78
function def: COPASI87
reaction: COPASI49
name: Rate Law for Reverse Cholesterol Transport
name: Rate Law for Peripheral Cholesterol Storage
compartment: 454202
reaction: COPASI44
species: COPASI7
name: Rate Law for Receptor Dependent Hepatic Uptake
species: COPASI19
function def: COPASI75
reaction: COPASI50
function def: COPASI77
species: COPASI33
species: COPASI6
name: Rate Law for Hepatic LDLR Synthesis
name: Rate Law for HDL Cholesterol Formation
reaction: COPASI58
reaction: COPASI62
reaction: COPASI53
is version of: GO:0008203
name: Rate Law for Hepatic Nascent HDL Synthesis
function def: COPASI85
name: Rate Law for Intestinal Cholesterol Synthesis
species: COPASI17
volume units: 406729
reaction: COPASI65
function def: COPASI84
compartment: 454214
reaction: COPASI56
species: COPASI13
species: COPASI35
function def: COPASI90
name: Rate Law for Cholesterol Excretion
species: COPASI25
compartment: 454226
reaction: COPASI68
reaction: COPASI71
is described by: http://identifiers.org/pubmed/23046614
time units: 406753
name: Rate Law for Release of Stored Peripheral Cholesterol
name: Rate Law for Intestinal Nascent HDL Synthesis

COPASI25
is version of: P01130
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454226
name: LDLC
type: Species

COPASI11
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454226
name: INHDLS
type: Species

406753
unit: 406765
name: time
type: SBMLUnitsDef

406862
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

COPASI54
kinetic law: 407882
modifier: 965443
product: 407870
reactant: 407858
fast: false
reversible: false
name: VLDL Cholesterol ReUptake
type: Reaction

COPASI68
kinetic law: 408674
modifier: 965719
product: 408662
reactant: 408650
fast: false
reversible: false
name: Peripheral Cholesterol Synthesis
type: Reaction

407258
stoichiometry: 1.0
species: COPASI11
type: SpeciesReference

407318
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

454178
constant: true
units: 406729
size: 1.0
spatial dimensions: 3.0
name: Intake
type: Compartment

COPASI40
kinetic law: 407006
modifier: 965203
product: 406994
reactant: 406982
is version of: GO:0015721
fast: false
reversible: false
name: Bile Salt Return
type: Reaction

COPASI22
is: SBO:0000291
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454202
name: HLDLRD
type: Species

COPASI12
is version of: Q00341
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454226
name: NHDL
type: Species

408146
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

408422
stoichiometry: 1.0
species: COPASI30
type: SpeciesReference

407402
stoichiometry: 1.0
species: COPASI14
type: SpeciesReference

COPASI69
fast: false
modifier: 965743
reactant: 408722
is version of: GO:0030301
product: 408734
modifier: 408746
name: CETP Mediated Transfer To VLDL
type: Reaction
reversible: false
kinetic law: 408758
modifier: 965731

COPASI55
modifier: 965455
fast: false
type: Reaction
kinetic law: 407954
reactant: 407906
modifier: 407930
reversible: false
modifier: 407942
name: IDL Cholesterol Formation
modifier: 965467
product: 407918

407186
value: 5.286E-4
name: k6
type: LocalParameter

407966
value: 0.43
name: k15
type: LocalParameter

408734
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

407750
stoichiometry: 1.0
species: COPASI20
type: SpeciesReference

COPASI23
is version of: P01130
constant: false
boundary condition: false
has only substance units: false
initial concentration: 20.0
initial amount: NaN
in compartment: 454226
name: IDLC
type: Species

COPASI41
kinetic law: 407054
modifier: 965215
product: 407042
reactant: 407030
is version of: GO:0015721
fast: false
reversible: false
name: Bile Salt Excretion
type: Reaction

COPASI13
is version of: CHEBI:16113
constant: false
boundary condition: false
has only substance units: false
initial concentration: 57516.0
initial amount: NaN
in compartment: 454214
name: PFC
type: Species

407030
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

COPASI21
is: SBO:0000291
constant: true
boundary condition: true
has only substance units: false
initial concentration: 600.0
initial amount: NaN
in compartment: 454202
name: HLDLRsS
type: Species

407798
value: 100.0
name: khrs
type: LocalParameter

408542
stoichiometry: 1.0
species: COPASI31
type: SpeciesReference

408650
stoichiometry: 1.0
species: COPASI34
type: SpeciesReference

408458
value: 0.017386
name: k23
type: LocalParameter

407486
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

407846
value: 0.01
name: k1
type: LocalParameter

407126
value: 2.66
name: k5
type: LocalParameter

COPASI20
is version of: P01130
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454202
name: HLDLRs
type: Species

407270
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

407198
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

408854
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

406982
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

407918
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

408362
stoichiometry: 1.0
species: COPASI27
type: SpeciesReference

408026
stoichiometry: 1.0
species: COPASI23
type: SpeciesReference

408590
stoichiometry: 1.0
species: COPASI12
type: SpeciesReference

COPASI39
kinetic law: 406958
modifier: 965191
product: 406946
reactant: 406934
is version of: GO:0015721
fast: false
reversible: false
name: Bile Salt Release
type: Reaction

COPASI59
kinetic law: 408170
modifier: 965539
product: 408158
reactant: 408146
fast: false
reversible: false
name: Receptor Independent Hepatic Uptake
type: Reaction

407498
stoichiometry: 1.0
species: COPASI15
type: SpeciesReference

407858
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

408530
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

408842
stoichiometry: 1.0
species: COPASI32
type: SpeciesReference

407570
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

407390
value: 5.0
name: BS
type: LocalParameter

COPASI38
reactant: 406850
modifier: 406874
product: 406862
modifier: 965179
name: Intestinal Cholesterol Synthesis
is version of: GO:0006695
fast: false
kinetic law: 406886
type: Reaction
reversible: false

407906
stoichiometry: 1.0
species: COPASI19
type: SpeciesReference

408038
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

408266
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

406898
value: 100.0
name: ICSmax
type: LocalParameter

408350
value: 100.0
name: kprs
type: LocalParameter

407870
stoichiometry: 1.0
species: COPASI9
type: SpeciesReference

COPASI58
modifier: 965527
kinetic law: 408122
reversible: false
reactant: 408086
modifier: 965515
fast: false
type: Reaction
name: Receptor Dependent Hepatic Uptake
product: 408098
modifier: 408110

406970
value: 6.0
name: k1
type: LocalParameter

406946
stoichiometry: 1.0
species: COPASI7
type: SpeciesReference

406741
exponent: 1.0
scale: 0
multipler: 1.0
kind: DIMENSIONLESS
type: SBMLUnit

COPASI37
kinetic law: 406826
modifier: 965167
product: 406814
reactant: 406802
is version of: GO:0070508
fast: false
reversible: false
name: Ingestion
type: Reaction

408794
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

408566
value: 5.0E-4
name: k1
type: LocalParameter

COPASI18
is: SBO:0000291
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454202
name: HNHDLS
type: Species

407546
value: 1.0
name: k9
type: LocalParameter

407822
stoichiometry: 1.0
species: COPASI22
type: SpeciesReference

COPASI47
kinetic law: 407438
modifier: 965323
modifier: 407426
product: 407414
reactant: 407402
fast: false
reversible: false
name: Hepatic Cholesterol Synthesis
type: Reaction

407462
value: 93925.0
name: HCSt
type: LocalParameter

407630
stoichiometry: 1.0
species: COPASI18
type: SpeciesReference

408074
value: 0.38
name: k17
type: LocalParameter

COPASI46
kinetic law: 407354
modifier: 965311
modifier: 407342
product: 407330
reactant: 407318
fast: false
reversible: false
name: Billary Cholesterol Release
type: Reaction

COPASI36
is version of: Q8WTV0
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454202
name: SRB1
type: Species

COPASI19
is version of: P98155
constant: false
boundary condition: false
has only substance units: false
initial concentration: 20.0
initial amount: NaN
in compartment: 454226
name: VLDLC
type: Species

406934
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

COPASI9
is version of: CHEBI:16113
constant: false
boundary condition: false
has only substance units: false
initial concentration: 60000.0
initial amount: NaN
in compartment: 454202
name: HFC
type: Species

454238
constant: true
units: 406729
size: 1.0
spatial dimensions: 3.0
name: Excreted
type: Compartment

408206
stoichiometry: 1.0
species: COPASI13
type: SpeciesReference

407378
value: 55326.0
name: BCRt
type: LocalParameter

COPASI8
is version of: CHEBI:22868
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454238
name: EBS
type: Species

408602
stoichiometry: 1.0
species: COPASI32
type: SpeciesReference

407474
value: 5.0
name: HS
type: LocalParameter

COPASI35
is version of: P11597
constant: false
boundary condition: false
has only substance units: false
initial concentration: 100.0
initial amount: NaN
in compartment: 454226
name: CETP
type: Species

COPASI49
type: Reaction
product: 407570
modifier: 965371
fast: false
modifier: 965359
modifier: 407594
modifier: 407582
reactant: 407558
kinetic law: 407606
reversible: false
name: Release of Stored Cholesterol

408890
value: 0.05
name: k29
type: LocalParameter

408086
stoichiometry: 1.0
species: COPASI25
type: SpeciesReference

406910
value: 3120.0
name: ICt
type: LocalParameter

407042
stoichiometry: 1.0
species: COPASI8
type: SpeciesReference

W3 CDTF: Tue Feb 12 15:37:44 GMT 2013

ORG:
  orgname: EMBL-EBI
n:
  given: Vijayalakshmi
  family: Chelliah

406838
value: 1.0
name: k1
type: LocalParameter

COPASI7
is version of: CHEBI:22868
constant: false
boundary condition: false
has only substance units: false
initial concentration: 467.0
initial amount: NaN
in compartment: 454190
name: IBS
type: Species

COPASI60
product: 408206
reactant: 408194
modifier: 408218
modifier: 965563
kinetic law: 408230
modifier: 965551
type: Reaction
fast: false
reversible: false
name: Receptor Dependent Peripheral Uptake

408374
stoichiometry: 1.0
species: COPASI29
type: SpeciesReference

407894
value: 0.0496
name: k1
type: LocalParameter

408014
value: 0.054
name: k1
type: LocalParameter

COPASI34
is: SBO:0000291
constant: true
boundary condition: true
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: 454214
name: PCS
type: Species

COPASI48
product: 407498
reactant: 407486
modifier: 965347
modifier: 965335
modifier: 407522
kinetic law: 407534
fast: false
modifier: 407510
reversible: false
type: Reaction
name: Hepatic Cholesterol Storage

406994
stoichiometry: 1.0
species: COPASI6
type: SpeciesReference

406922
value: 5.0
name: IS
type: LocalParameter

408302
stoichiometry: 1.0
species: COPASI28
type: SpeciesReference

407738
stoichiometry: 1.0
species: COPASI21
type: SpeciesReference

407210
stoichiometry: 1.0
species: COPASI10
type: SpeciesReference

W3 CDTF: Tue Nov 27 16:32:48 GMT 2012

COPASI61
kinetic law: 408278
modifier: 965575
product: 408266
reactant: 408254
fast: false
reversible: false
name: Receptor Independent Peripheral Uptake
type: Reaction

407138
stoichiometry: 1.0
species: COPASI4
type: SpeciesReference

given: Mark
family: Mc Auley

orgname: Liverpool Hope University