513850
stoichiometry: 1.0
species: 307016
type: SpeciesReference

307123
constant: true
value: 1.0
name: Cdh1T
type: Parameter

307010
in compartment: 307002
type: Species
initial amount: NaN
has only substance units: false
is: SBO:0000252
name: securinT
boundary condition: false
initial concentration: 0.6
is version of: P40316
constant: false

514432
stoichiometry: 1.0
species: 307025
type: SpeciesReference

514079
stoichiometry: 1.0
species: 307003
type: SpeciesReference

307037
product: 513367
name: v5
fast: false
is version of: GO:0006464
modifier: 513379
is: SBO:0000181
kinetic law: 513392
reactant: 513355
type: Reaction
reversible: true

BIOMD0000000409
parameter: 307136
parameter: 307146
parameter: 307142
parameter: 307132
parameter: 307117
parameter: 307113
reaction: 307053
species: 307008
parameter: 307121
parameter: 307108
is: MODEL5951818256
species: 307030
parameter: 307112
parameter: 307122
species: 307014
area units: area
species: 307026
species: 307021
rule: 307101
species: 307018
substance units: substance
parameter: 307165
parameter: 307175
rule: 307093
parameter: 307171
species: 307020
parameter: 307156
parameter: 307166
species: 307004
compartment: 307002
parameter: 307170
reaction: 307062
parameter: 307151
rule: 307105
reaction: 307063
parameter: 307147
reaction: 307038
parameter: 307143
reaction: 307046
reaction: 307056
rule: 307096
parameter: 307150
reaction: 307064
parameter: 307138
parameter: 307148
is version of: GO:0000278
reaction: 307037
reaction: 307047
parameter: 307115
parameter: 307123
parameter: 307133
curated: true
rule: 307100
reaction: 307032
parameter: 307118
species: 307011
species: 307023
species: 307003
parameter: 307120
is version of: CCO:P0000038
reaction: 307041
parameter: 307167
parameter: 307168
species: 307006
length unit: length
species: 307013
rule: 307103
species: 307025
parameter: 307172
parameter: 307157
parameter: 307153
species: 307029
rule: 307095
parameter: 307161
volume units: volume
reaction: 307048
reaction: 307058
species: 307016
parameter: 307152
parameter: 307162

307152
constant: true
value: 0.25
name: Jpolo
type: Parameter

513452
stoichiometry: 1.0
species: 307010
type: SpeciesReference

307066
fast: false
is: SBO:0000393
reactant: 514505
modifier: 514541
name: v27
reversible: true
kinetic law: 514553
modifier: 514529
type: Reaction
is version of: GO:0006412
product: 514517

307137
constant: true
value: 2.0
name: kap
type: Parameter

513221
stoichiometry: 1.0
species: 307005
type: SpeciesReference

513173
stoichiometry: 1.0
species: 307003
type: SpeciesReference

514007
stoichiometry: 1.0
species: 307018
type: SpeciesReference

307162
constant: true
value: 0.5
name: kaacdc15
type: Parameter

513367
stoichiometry: 1.0
species: 307008
type: SpeciesReference

307026
initial amount: NaN
name: inactive Cdc15
is: SBO:0000252
type: Species
is version of: P27636
has only substance units: false
initial concentration: NaN
boundary condition: true
in compartment: 307002
constant: false

307011
has only substance units: false
is: SBO:0000252
is version of: P40316
in compartment: 307002
initial concentration: NaN
constant: false
type: Species
name: securin
initial amount: NaN
boundary condition: true

307110
constant: true
value: 0.03
name: ksclb2
type: Parameter

514200
stoichiometry: 1.0
species: 307020
type: SpeciesReference

307036
is version of: GO:0030163
type: Reaction
fast: false
reversible: true
name: v4
is: SBO:0000179
reactant: 513306
modifier: 513330
product: 513318
kinetic law: 513343

513209
stoichiometry: 1.0
species: 307004
type: SpeciesReference

307151
constant: true
value: 0.1
name: kipolo
type: Parameter

307138
constant: true
value: 0.2
name: Jnet
type: Parameter

307067
kinetic law: 514589
product: 514577
reactant: 514565
is version of: GO:0030163
is: SBO:0000179
fast: false
reversible: true
name: v28
type: Reaction

307161
constant: true
value: 0.02
name: kacdc15
type: Parameter

513404
stoichiometry: 1.0
species: 307008
type: SpeciesReference

307121
constant: true
value: 1.0
name: kapcdh
type: Parameter

307025
constant: false
initial amount: NaN
type: Species
is: SBO:0000252
name: Cdc15
boundary condition: false
in compartment: 307002
has only substance units: false
is version of: P27636
initial concentration: 0.0257

307039
fast: false
product: 513452
is: SBO:0000393
type: Reaction
name: v7
kinetic law: 513476
product: 513464
reactant: 513440
is version of: GO:0006412
reversible: true

307111
constant: true
value: 0.03
name: kdclb2
type: Parameter

513862
stoichiometry: 1.0
species: 307030
type: SpeciesReference

513185
stoichiometry: 1.0
species: 307004
type: SpeciesReference

307150
constant: true
value: 0.5
name: kaapolo
type: Parameter

513464
stoichiometry: 1.0
species: 307011
type: SpeciesReference

514103
stoichiometry: 1.0
species: 307021
type: SpeciesReference

307064
kinetic law: 514493
product: 514481
reactant: 514469
is version of: GO:0006464
is: SBO:0000181
fast: false
reversible: true
name: v26
type: Reaction

307024
boundary condition: true
initial amount: NaN
name: inactive Tem1
constant: false
initial concentration: NaN
type: Species
has only substance units: false
in compartment: 307002
is: SBO:0000252
is version of: P38987

307122
constant: true
value: 0.0015
name: Jcdh
type: Parameter

307038
kinetic law: 513428
product: 513416
reactant: 513404
is version of: GO:0006464
is: SBO:0000181
fast: false
reversible: true
name: v6
type: Reaction

514152
stoichiometry: 1.0
species: 307005
type: SpeciesReference

307112
constant: true
value: 0.2
name: kadclb2
type: Parameter

514250
stoichiometry: 1.0
species: 307021
type: SpeciesReference

307163
constant: true
value: 0.0
name: kicdc15
type: Parameter

ORG:
  orgname: EMBL-EBI
n:
  given: Lukas
  family: Endler

307051
is: SBO:0000526
fast: false
name: v15
modifier: 513947
type: Reaction
kinetic law: 513959
reactant: 513923
product: 513935
is version of: GO:0006461
reversible: true

307113
constant: true
value: 2.0
name: kaadclb2
type: Parameter

513318
stoichiometry: 1.0
species: 307005
type: SpeciesReference

307127
constant: true
value: 2.0
name: kadsecurin
type: Parameter

513560
stoichiometry: 1.0
species: 307013
type: SpeciesReference

307147
constant: true
value: 0.25
name: kadpolo
type: Parameter

514649
stoichiometry: 1.0
species: 307028
type: SpeciesReference

307156
constant: true
value: 0.1
name: kitem
type: Parameter

307166
constant: true
value: 0.2
name: Jcdc15
type: Parameter

307133
constant: true
value: 0.1
name: kad
type: Parameter

514469
stoichiometry: 1.0
species: 307025
type: SpeciesReference

513935
stoichiometry: 1.0
species: 307018
type: SpeciesReference

513548
stoichiometry: 1.0
species: 307003
type: SpeciesReference

307175
constant: true
value: 0.0
name: Inh
type: Parameter

307148
constant: true
value: 0.0
name: kapolo
type: Parameter

514140
stoichiometry: 1.0
species: 307021
type: SpeciesReference

307128
constant: true
value: 0.001
name: ksseparase
type: Parameter

307155
constant: true
value: 0.5
name: kaatem
type: Parameter

307165
constant: true
value: 0.2
name: kaicdc15
type: Parameter

513572
stoichiometry: 1.0
species: 307014
type: SpeciesReference

513306
stoichiometry: 1.0
species: 307006
type: SpeciesReference

307115
constant: true
value: 0.015
name: kscdc20
type: Parameter

513608
stoichiometry: 1.0
species: 307014
type: SpeciesReference

514019
stoichiometry: 1.0
species: 307030
type: SpeciesReference

307125
constant: true
value: 0.03
name: kssecurin
type: Parameter

514091
stoichiometry: 1.0
species: 307019
type: SpeciesReference

307029
initial amount: NaN
constant: false
initial concentration: NaN
is version of: Q00362
name: PP2A
type: Species
has only substance units: false
is: SBO:0000252
boundary condition: true
in compartment: 307002

307145
constant: true
value: 0.01
name: kspolo
type: Parameter

513488
stoichiometry: 1.0
species: 307010
type: SpeciesReference

307049
is version of: GO:0016310
fast: false
type: Reaction
reactant: 513850
reversible: true
product: 513862
is: SBO:0000216
modifier: 513874
modifier: 513886
name: Net1 phosphorylation
modifier: 513898
kinetic law: 513910

307009
initial amount: NaN
in compartment: 307002
is: SBO:0000252
name: inactive Cdh1
constant: false
is version of: P53197
type: Species
initial concentration: NaN
boundary condition: true
has only substance units: false

307135
constant: true
value: 0.45
name: kd
type: Parameter

307068
is: SBO:0000179
name: Tem1 degradation in MEN
is version of: GO:0030163
reversible: true
kinetic law: 514637
reactant: 514601
type: Reaction
modifier: 514613
modifier: 514625
fast: false

307168
constant: true
value: 0.1
name: ldmen
type: Parameter

307116
constant: true
value: 0.05
name: kdcdc20
type: Parameter

513923
stoichiometry: 1.0
species: 307016
type: SpeciesReference

307173
constant: true
value: 1.0
name: PP2AT
type: Parameter

W3 CDTF: Mon Jul 16 13:01:33 BST 2012

307028
initial concentration: 8.0E-6
name: MEN
boundary condition: false
in compartment: 307002
is: SBO:0000297
constant: false
has only substance units: false
initial amount: NaN
has part: P27636
type: Species
has part: P38987

307126
constant: true
value: 0.05
name: kdsecurin
type: Parameter

307153
constant: true
value: 0.0
name: katem
type: Parameter

513620
stoichiometry: 1.0
species: 307005
type: SpeciesReference

514481
stoichiometry: 1.0
species: 307026
type: SpeciesReference

307048
modifier: 513814
reversible: true
modifier: 513826
type: Reaction
fast: false
product: 513790
reactant: 513778
name: Net1P dephosphorylation
is: SBO:0000330
kinetic law: 513838
is version of: GO:0016311
modifier: 513802

307146
constant: true
value: 0.01
name: kdpolo
type: Parameter

307008
name: Cdh1
initial amount: NaN
is: SBO:0000252
initial concentration: 3.8E-5
in compartment: 307002
constant: false
type: Species
has only substance units: false
is version of: P53197
boundary condition: false

307136
constant: true
value: 0.4
name: kp
type: Parameter

307069
modifier: 514661
fast: false
kinetic law: 514685
reversible: true
is: SBO:0000179
modifier: 514673
reactant: 514649
type: Reaction
is version of: GO:0030163
name: Cdc15 degradation in MEN

307167
constant: true
value: 10.0
name: lamen
type: Parameter

307057
product: 514200
reactant: 514188
modifier: 514213
kinetic law: 514225
type: Reaction
is version of: GO:0006464
is: SBO:0000181
fast: false
reversible: true
name: v20

514565
stoichiometry: 1.0
species: 307028
type: SpeciesReference

307047
kinetic law: 513766
product: 513753
reactant: 513741
is version of: GO:0043241
is: SBO:0000179
fast: false
reversible: true
name: securin:separase separase degradation
type: Reaction

307018
has only substance units: false
initial concentration: 0.485
initial amount: NaN
constant: false
name: Net1Cdc14
has part: P47035
is: SBO:0000297
in compartment: 307002
type: Species
boundary condition: false
has part: Q00684

307143
constant: true
value: 0.5
name: Cdc14T
type: Parameter

513983
stoichiometry: 1.0
species: 307016
type: SpeciesReference

514384
stoichiometry: 1.0
species: 307024
type: SpeciesReference

307004
initial concentration: 0.997
type: Species
in compartment: 307002
name: Clb2
is version of: P24869
has only substance units: false
initial amount: NaN
boundary condition: false
is: SBO:0000252
constant: false

307171
constant: true
value: 0.1
name: kpp
type: Parameter

307056
name: v19
reactant: 514140
fast: false
kinetic law: 514176
is version of: GO:0030163
is: SBO:0000179
type: Reaction
reactant: 514128
modifier: 514164
product: 514152
reversible: true

307130
constant: true
value: 0.004
name: kdseparase
type: Parameter

307019
boundary condition: false
constant: false
is: SBO:0000252
type: Species
has only substance units: false
name: PoloT
in compartment: 307002
initial amount: NaN
is version of: P32562
initial concentration: 0.99

307046
fast: false
type: Reaction
reactant: 513692
name: securinseparase securindegradation
reversible: true
is version of: GO:0043241
product: 513704
modifier: 513716
kinetic law: 513729
is: SBO:0000179

514287
stoichiometry: 1.0
species: 307005
type: SpeciesReference

514420
stoichiometry: 1.0
species: 307026
type: SpeciesReference

513971
stoichiometry: 1.0
species: 307018
type: SpeciesReference

307172
constant: true
value: 20.0
name: ki
type: Parameter

307005
is: SBO:0000291
constant: true
boundary condition: true
has only substance units: false
initial concentration: 1.0
initial amount: NaN
in compartment: 307002
name: degr
type: Species

513355
stoichiometry: 1.0
species: 307009
type: SpeciesReference

513644
stoichiometry: 1.0
species: 307011
type: SpeciesReference

307059
fast: false
type: Reaction
reversible: true
is version of: GO:0030163
is: SBO:0000179
modifier: 514299
name: v22
reactant: 514274
product: 514287
kinetic law: 514311

307108
constant: false
value: NaN
name: Cdk activity
type: Parameter

307141
constant: true
value: 1.0
name: ldnet
type: Parameter

307131
constant: true
value: 500.0
name: lasecurin
type: Parameter

307158
constant: true
value: 0.005
name: Jtem1
type: Parameter

307118
constant: true
value: 0.01
name: kdcdh
type: Parameter

307031
is: SBO:0000252
is version of: Q00684
constant: false
has only substance units: false
type: Species
initial amount: NaN
boundary condition: true
name: Cdc14
initial concentration: NaN
in compartment: 307002

514577
stoichiometry: 1.0
species: 307005
type: SpeciesReference

307016
name: Net1
initial amount: NaN
initial concentration: 0.098
is: SBO:0000252
constant: false
type: Species
has only substance units: false
boundary condition: false
is version of: P47035
in compartment: 307002

307006
type: Species
in compartment: 307002
name: Cdc20
initial amount: NaN
is: SBO:0000252
constant: false
is version of: P26309
initial concentration: 0.0
boundary condition: false
has only substance units: false

514128
stoichiometry: 1.0
species: 307019
type: SpeciesReference

514372
stoichiometry: 1.0
species: 307023
type: SpeciesReference

307058
kinetic law: 514262
product: 514250
reactant: 514238
is version of: GO:0006464
is: SBO:0000181
fast: false
reversible: true
name: v21
type: Reaction

307132
constant: true
value: 1.0
name: ldsecurin
type: Parameter

307044
fast: false
reactant: 513656
kinetic law: 513680
type: Reaction
is: SBO:0000526
is version of: GO:0006461
reversible: true
product: 513668
name: v11
reactant: 513644

307142
constant: true
value: 1.0
name: Net1T
type: Parameter

307157
constant: true
value: 1.0
name: kaitem
type: Parameter

307117
constant: true
value: 2.0
name: kadcdc20
type: Parameter

513596
stoichiometry: 1.0
species: 307013
type: SpeciesReference

307030
is: SBO:0000297
name: Net1P
is version of: C00562
constant: false
initial concentration: NaN
in compartment: 307002
has only substance units: false
is version of: P47035
type: Species
initial amount: NaN
boundary condition: true

513692
stoichiometry: 1.0
species: 307015
type: SpeciesReference

307170
constant: true
value: 1.0
name: Cdc15T
type: Parameter

513512
stoichiometry: 1.0
species: 307005
type: SpeciesReference

307053
reversible: true
modifier: 514055
product: 514019
fast: false
reactant: 514007
is: SBO:0000216
name: Net1Cdc14 phosphorylation
kinetic law: 514067
type: Reaction
modifier: 514043
modifier: 514031
is version of: GO:0016310

513416
stoichiometry: 1.0
species: 307009
type: SpeciesReference

307043
type: Reaction
reactant: 513608
product: 513620
is: SBO:0000179
kinetic law: 513632
name: v10
reversible: true
fast: false
reactant: 513596
is version of: GO:0030163

307063
is: SBO:0000181
fast: false
reversible: true
modifier: 514444
product: 514432
kinetic law: 514456
name: v25
reactant: 514420
is version of: GO:0006464
type: Reaction

514274
stoichiometry: 1.0
species: 307020
type: SpeciesReference

307033
is: SBO:0000179
fast: false
modifier: 513245
reversible: true
name: v2
reactant: 513209
kinetic law: 513257
is version of: GO:0030163
product: 513221
modifier: 513233
type: Reaction

514238
stoichiometry: 1.0
species: 307020
type: SpeciesReference

514188
stoichiometry: 1.0
species: 307021
type: SpeciesReference

513778
stoichiometry: 1.0
species: 307030
type: SpeciesReference

307014
boundary condition: true
has only substance units: false
name: separase
initial amount: NaN
in compartment: 307002
is: SBO:0000252
constant: false
initial concentration: NaN
type: Species
is version of: Q03018

513656
stoichiometry: 1.0
species: 307014
type: SpeciesReference

307023
initial amount: NaN
has only substance units: false
is: SBO:0000252
name: Tem1
boundary condition: false
constant: false
in compartment: 307002
initial concentration: 0.00389
type: Species
is version of: P38987

514323
stoichiometry: 1.0
species: 307024
type: SpeciesReference

307062
kinetic law: 514408
modifier: 514396
product: 514384
name: v24
is: SBO:0000181
fast: false
is version of: GO:0006464
type: Reaction
reversible: true
reactant: 514372

307052
kinetic law: 513995
product: 513983
reactant: 513971
is version of: GO:0043241
is: SBO:0000180
fast: false
reversible: true
name: v16
type: Reaction

514517
stoichiometry: 1.0
species: 307028
type: SpeciesReference

307140
constant: true
value: 500.0
name: lanet
type: Parameter

307042
type: Reaction
product: 513572
reactant: 513548
fast: false
is version of: GO:0006412
kinetic law: 513584
is: SBO:0000393
reversible: true
name: v9
product: 513560

307032
kinetic law: 513197
product: 513185
reactant: 513173
is version of: GO:0006412
is: SBO:0000393
fast: false
reversible: true
name: v1
type: Reaction

513741
stoichiometry: 1.0
species: 307015
type: SpeciesReference

513790
stoichiometry: 1.0
species: 307016
type: SpeciesReference

307015
name: securin:separase
initial amount: NaN
has part: Q03018
has part: P40316
constant: false
initial concentration: 0.248
type: Species
is: SBO:0000297
boundary condition: false
in compartment: 307002
has only substance units: false

513281
stoichiometry: 1.0
species: 307006
type: SpeciesReference

307120
constant: true
value: 1.0
name: kadcdh
type: Parameter

307061
type: Reaction
reversible: true
fast: false
product: 514335
reactant: 514323
is: SBO:0000181
name: v23
is version of: GO:0006464
kinetic law: 514360
modifier: 514347

513500
stoichiometry: 1.0
species: 307011
type: SpeciesReference

307041
reactant: 513500
modifier: 513524
reversible: true
fast: false
name: v8
type: Reaction
product: 513512
kinetic law: 513536
is version of: GO:0030163
reactant: 513488
is: SBO:0000179

513704
stoichiometry: 1.0
species: 307014
type: SpeciesReference

513668
stoichiometry: 1.0
species: 307015
type: SpeciesReference

307002
is version of: GO:0005623
is: SBO:0000290
constant: true
size: 1.0
spatial dimensions: 3.0
name: compartment
type: Compartment

307021
is version of: P32562
boundary condition: true
initial amount: NaN
initial concentration: NaN
is: SBO:0000252
in compartment: 307002
name: inactive Polo
constant: false
type: Species
has only substance units: false

514505
stoichiometry: 1.0
species: 307003
type: SpeciesReference

307160
constant: true
value: 1.0
name: Tem1T
type: Parameter

513440
stoichiometry: 1.0
species: 307003
type: SpeciesReference

307054
reactant: 514079
product: 514103
product: 514091
is version of: GO:0006412
fast: false
type: Reaction
name: v18
kinetic law: 514115
is: SBO:0000393
reversible: true

513269
stoichiometry: 1.0
species: 307003
type: SpeciesReference

307003
is: SBO:0000291
type: Species
name: AA
constant: true
is version of: CHEBI:33704
in compartment: 307002
boundary condition: true
has only substance units: false
initial concentration: 1.0
initial amount: NaN

514601
stoichiometry: 1.0
species: 307028
type: SpeciesReference

307034
kinetic law: 513294
product: 513281
reactant: 513269
is version of: GO:0006412
is: SBO:0000393
fast: false
reversible: true
name: v3
type: Reaction

514335
stoichiometry: 1.0
species: 307023
type: SpeciesReference

307020
has only substance units: false
initial amount: NaN
name: Polo
type: Species
initial concentration: 0.945
in compartment: 307002
is version of: P32562
is: SBO:0000252
boundary condition: false
constant: false

307013
has only substance units: false
initial amount: NaN
initial concentration: 0.25
in compartment: 307002
name: separaseT
is version of: Q03018
boundary condition: false
is: SBO:0000252
constant: false
type: Species

513753
stoichiometry: 1.0
species: 307011
type: SpeciesReference

W3 CDTF: Thu Aug 20 17:15:09 BST 2009

orgname: EMBL-EBI

given: Vijayalakshmi
family: Chelliah