911725
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species: metaid_0000182
type: SpeciesReference

metaid_0000231
kinetic law: 911035
product: 911023
product: 911011
reactant: 910999
fast: false
reversible: false
type: Reaction

910346
stoichiometry: 1.0
species: metaid_0000157
type: SpeciesReference

metaid_0000245
kinetic law: 911713
product: 911701
reactant: 911689
reactant: 911677
fast: false
reversible: false
type: Reaction

909921
stoichiometry: 1.0
species: metaid_0000134
type: SpeciesReference

910383
stoichiometry: 1.0
species: metaid_0000120
type: SpeciesReference

909970
stoichiometry: 1.0
species: metaid_0000154
type: SpeciesReference

metaid_0000251
kinetic law: 912006
product: 911994
reactant: 911982
reactant: 911969
fast: false
reversible: false
type: Reaction

912042
stoichiometry: 1.0
species: metaid_0000187
type: SpeciesReference

909530
stoichiometry: 1.0
species: metaid_0000140
type: SpeciesReference

911459
stoichiometry: 1.0
species: metaid_0000178
type: SpeciesReference

metaid_0000265
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: AT_XIa_l
type: Species

911835
stoichiometry: 1.0
species: metaid_0000184
type: SpeciesReference

metaid_0000246
kinetic law: 911761
product: 911749
product: 911737
reactant: 911725
fast: false
reversible: false
type: Reaction

metaid_0000232
kinetic law: 911083
product: 911071
reactant: 911059
reactant: 911047
fast: false
reversible: false
type: Reaction

909131
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

metaid_0000252
kinetic law: 912054
product: 912042
reactant: 912030
reactant: 912018
fast: false
reversible: false
type: Reaction

909095
stoichiometry: 1.0
species: metaid_0000122
type: SpeciesReference

911920
stoichiometry: 1.0
species: metaid_0000173
type: SpeciesReference

909035
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

911047
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

911095
stoichiometry: 1.0
species: metaid_0000168
type: SpeciesReference

metaid_0000243
kinetic law: 911616
product: 911604
reactant: 911592
reactant: 911580
fast: false
reversible: false
type: Reaction

metaid_0000233
kinetic law: 911131
product: 911119
product: 911107
reactant: 911095
fast: false
reversible: false
type: Reaction

metaid_0000020
constant: true
value: 0.335
type: Parameter

910395
stoichiometry: 1.0
species: metaid_0000160
type: SpeciesReference

909615
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

911737
stoichiometry: 1.0
species: metaid_0000118
type: SpeciesReference

910419
stoichiometry: 1.0
species: metaid_0000160
type: SpeciesReference

metaid_0000253
kinetic law: 912102
product: 912090
product: 912078
reactant: 912066
fast: false
reversible: false
type: Reaction

911823
stoichiometry: 1.0
species: metaid_0000148
type: SpeciesReference

912030
stoichiometry: 1.0
species: metaid_0000169
type: SpeciesReference

910102
stoichiometry: 1.0
species: metaid_0000156
type: SpeciesReference

metaid_0000263
kinetic law: 912247
product: 912235
reactant: 912223
reactant: 912211
fast: false
reversible: false
name: R34
type: Reaction

metaid_0000040
constant: true
value: 0.005
type: Parameter

910758
stoichiometry: 1.0
species: metaid_0000116
type: SpeciesReference

metaid_0000234
kinetic law: 911180
product: 911168
reactant: 911156
reactant: 911143
fast: false
reversible: false
type: Reaction

metaid_0000244
kinetic law: 911664
product: 911652
product: 911640
reactant: 911628
fast: false
reversible: false
type: Reaction

metaid_0000254
unit: 908914
name: nano mole
type: SBMLUnitsDef

909603
stoichiometry: 1.0
species: metaid_0000143
type: SpeciesReference

910054
stoichiometry: 1.0
species: metaid_0000150
type: SpeciesReference

910297
stoichiometry: 1.0
species: metaid_0000159
type: SpeciesReference

909023
stoichiometry: 1.0
species: metaid_0000119
type: SpeciesReference

911156
stoichiometry: 1.0
species: metaid_0000170
type: SpeciesReference

910138
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

911435
stoichiometry: 1.0
species: metaid_0000173
type: SpeciesReference

910186
stoichiometry: 1.0
species: metaid_0000134
type: SpeciesReference

metaid_0000241
kinetic law: 911519
product: 911507
reactant: 911495
reactant: 911483
fast: false
reversible: false
type: Reaction

909144
stoichiometry: 1.0
species: metaid_0000124
type: SpeciesReference

metaid_0000042
constant: true
value: 0.005
type: Parameter

metaid_0000069
constant: true
value: 0.1
type: Parameter

910673
stoichiometry: 1.0
species: metaid_0000128
type: SpeciesReference

909627
stoichiometry: 1.0
species: metaid_0000144
type: SpeciesReference

metaid_0000255
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2600.0
initial amount: NaN
in compartment: metaid_0000114
name: alpha2M_l
type: Species

911701
stoichiometry: 1.0
species: metaid_0000182
type: SpeciesReference

metaid_0000059
constant: true
value: 8.3
type: Parameter

metaid_0000032
constant: true
value: 0.2
type: Parameter

910322
stoichiometry: 1.0
species: metaid_0000159
type: SpeciesReference

909945
stoichiometry: 1.0
species: metaid_0000136
type: SpeciesReference

912211
stoichiometry: 1.0
species: metaid_0000255
type: SpeciesReference

909071
stoichiometry: 1.0
species: metaid_0000121
type: SpeciesReference

911944
stoichiometry: 1.0
species: metaid_0000186
type: SpeciesReference

metaid_0000242
kinetic law: 911568
product: 911555
reactant: 911543
reactant: 911531
fast: false
reversible: false
type: Reaction

metaid_0000256
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: alpha2M_IIa_l
type: Species

metaid_0000041
constant: true
value: 0.005
type: Parameter

911119
stoichiometry: 1.0
species: metaid_0000169
type: SpeciesReference

910284
stoichiometry: 1.0
species: metaid_0000157
type: SpeciesReference

metaid_0000031
constant: true
value: 0.05
type: Parameter

911447
stoichiometry: 1.0
species: metaid_0000133
type: SpeciesReference

908914
exponent: 1.0
scale: -9
multipler: 1.0
kind: MOLE
type: SBMLUnit

911847
stoichiometry: 1.0
species: metaid_0000185
type: SpeciesReference

911240
stoichiometry: 1.0
species: metaid_0000122
type: SpeciesReference

910126
stoichiometry: 1.0
species: metaid_0000156
type: SpeciesReference

metaid_0000257
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: alpha2M_Xa_l
type: Species

910334
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

911143
stoichiometry: 1.0
species: metaid_0000130
type: SpeciesReference

910371
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

metaid_0000044
constant: true
value: 2.09
type: Parameter

metaid_0000057
constant: true
value: 0.1
type: Parameter

910685
stoichiometry: 1.0
species: metaid_0000164
type: SpeciesReference

metaid_0000030
constant: true
value: 3.5
type: Parameter

911059
stoichiometry: 1.0
species: metaid_0000167
type: SpeciesReference

911932
stoichiometry: 1.0
species: metaid_0000117
type: SpeciesReference

909047
stoichiometry: 1.0
species: metaid_0000120
type: SpeciesReference

metaid_0000230
kinetic law: 910987
product: 910975
reactant: 910963
reactant: 910951
fast: false
reversible: false
type: Reaction

metaid_0000240
kinetic law: 911471
product: 911459
reactant: 911447
reactant: 911435
fast: false
reversible: false
type: Reaction

912223
stoichiometry: 1.0
species: metaid_0000137
type: SpeciesReference

909083
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

910272
stoichiometry: 1.0
species: metaid_0000136
type: SpeciesReference

metaid_0000258
constant: true
value: 2.3E-6
type: Parameter

metaid_0000043
constant: true
value: 0.01
type: Parameter

910999
stoichiometry: 1.0
species: metaid_0000180
type: SpeciesReference

909762
stoichiometry: 1.0
species: metaid_0000149
type: SpeciesReference

910198
stoichiometry: 1.0
species: metaid_0000157
type: SpeciesReference

909337
stoichiometry: 1.0
species: metaid_0000132
type: SpeciesReference

911107
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

metaid_0000058
constant: true
value: 10.7
type: Parameter

metaid_0000112
constant: true
value: 1.417
type: Parameter

metaid_0000065
constant: true
value: 0.023
type: Parameter

909325
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

metaid_0000181
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: V_mIIa_l
type: Species

metaid_0000046
constant: true
value: 0.1
type: Parameter

metaid_0000036
constant: true
value: 0.17
type: Parameter

metaid_0000055
constant: true
value: 1.0
type: Parameter

910927
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

910078
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

metaid_0000016
constant: true
value: 0.227
type: Parameter

912235
stoichiometry: 1.0
species: metaid_0000257
type: SpeciesReference

908999
stoichiometry: 1.0
species: metaid_0000118
type: SpeciesReference

metaid_0000190
kinetic law: 909059
product: 909047
reactant: 909035
reactant: 909023
fast: false
reversible: false
name: Factor V lipid binding
type: Reaction

metaid_0000132
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: IX_l
type: Species

metaid_0000075
constant: true
value: 66.0
type: Parameter

metaid_0000180
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: VII_Xa_l
type: Species

metaid_0000026
constant: true
value: 1.9
type: Parameter

metaid_0000085
constant: true
value: 1.6
type: Parameter

909749
stoichiometry: 1.0
species: metaid_0000126
type: SpeciesReference

metaid_0000113
constant: true
value: 0.183
type: Parameter

910527
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

metaid_0000066
constant: true
value: 0.1
type: Parameter

909775
stoichiometry: 1.0
species: metaid_0000150
type: SpeciesReference

911896
stoichiometry: 1.0
species: metaid_0000184
type: SpeciesReference

metaid_0000035
constant: true
value: 0.057
type: Parameter

metaid_0000045
constant: true
value: 0.34
type: Parameter

909119
stoichiometry: 1.0
species: metaid_0000123
type: SpeciesReference

metaid_0000056
constant: true
value: 1.0
type: Parameter

909168
stoichiometry: 1.0
species: metaid_0000125
type: SpeciesReference

metaid_0000015
constant: true
value: 0.05
type: Parameter

metaid_0000076
constant: true
value: 13.0
type: Parameter

metaid_0000133
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: IXa_f
type: Species

911969
stoichiometry: 1.0
species: metaid_0000142
type: SpeciesReference

metaid_0000086
constant: true
value: 0.4
type: Parameter

908926
stoichiometry: 1.0
species: metaid_0000115
type: SpeciesReference

metaid_0000025
constant: true
value: 0.01
type: Parameter

910722
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

metaid_0000034
constant: true
value: 0.335
type: Parameter

metaid_0000048
constant: true
value: 1.5
type: Parameter

metaid_0000067
constant: true
value: 6.94
type: Parameter

metaid_0000100
constant: true
value: 0.1
type: Parameter

911604
stoichiometry: 1.0
species: metaid_0000181
type: SpeciesReference

910915
stoichiometry: 1.0
species: metaid_0000158
type: SpeciesReference

metaid_0000110
constant: true
value: 0.5
type: Parameter

metaid_0000053
constant: true
value: 0.1
type: Parameter

909313
stoichiometry: 1.0
species: metaid_0000131
type: SpeciesReference

metaid_0000193
kinetic law: 909205
product: 909193
reactant: 909180
reactant: 909168
fast: false
reversible: false
name: Factor VIIa lipid binding
type: Reaction

metaid_0000090
constant: true
value: 0.016
type: Parameter

metaid_0000130
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: VIIIa_l
type: Species

metaid_0000073
constant: true
value: 100.0
type: Parameter

metaid_0000014
constant: true
value: 0.66
type: Parameter

metaid_0000028
constant: true
value: 3.3
type: Parameter

metaid_0000120
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: V_l
type: Species

metaid_0000087
constant: true
value: 0.1
type: Parameter

metaid_0000047
constant: true
value: 32.5
type: Parameter

metaid_0000033
constant: true
value: 0.05
type: Parameter

metaid_0000101
constant: true
value: 13.8
type: Parameter

metaid_0000054
constant: true
value: 0.2
type: Parameter

910539
stoichiometry: 1.0
species: metaid_0000130
type: SpeciesReference

metaid_0000068
constant: true
value: 0.23
type: Parameter

metaid_0000111
constant: true
value: 0.01
type: Parameter

metaid_0000192
kinetic law: 909156
product: 909144
reactant: 909131
reactant: 909119
fast: false
reversible: false
name: Factor VII lipid binding
type: Reaction

metaid_0000091
constant: true
value: 3.3E-4
type: Parameter

metaid_0000131
constant: false
boundary condition: false
has only substance units: false
initial concentration: 90.0
initial amount: NaN
in compartment: metaid_0000114
name: IX_f
type: Species

metaid_0000191
kinetic law: 909107
product: 909095
reactant: 909083
reactant: 909071
fast: false
reversible: false
name: Factor Va lipid binding
type: Reaction

912078
stoichiometry: 1.0
species: metaid_0000134
type: SpeciesReference

908938
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

metaid_0000013
constant: true
value: 0.05
type: Parameter

metaid_0000074
constant: true
value: 0.1
type: Parameter

909958
stoichiometry: 1.0
species: metaid_0000150
type: SpeciesReference

911168
stoichiometry: 1.0
species: metaid_0000171
type: SpeciesReference

metaid_0000027
constant: true
value: 0.029
type: Parameter

911350
stoichiometry: 1.0
species: metaid_0000172
type: SpeciesReference

metaid_0000088
constant: true
value: 1.6
type: Parameter

metaid_0000121
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: Va_f
type: Species

metaid_0000051
constant: true
value: 44.8
type: Parameter

metaid_0000092
constant: true
value: 0.01
type: Parameter

metaid_0000261
kinetic law: 912151
product: 912139
reactant: 912126
reactant: 912114
fast: false
reversible: false
name: R32
type: Reaction

911023
stoichiometry: 1.0
species: metaid_0000126
type: SpeciesReference

metaid_0000061
constant: true
value: 1.0
type: Parameter

metaid_0000136
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: X_l
type: Species

metaid_0000089
constant: true
value: 0.4
type: Parameter

metaid_0000122
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: Va_l
type: Species

metaid_0000079
constant: true
value: 44.8
type: Parameter

metaid_0000012
constant: true
value: 0.17
type: Parameter

metaid_0000022
constant: true
value: 0.115
type: Parameter

metaid_0000222
kinetic law: 910600
product: 910588
reactant: 910576
reactant: 910564
fast: false
reversible: false
type: Reaction

metaid_0000093
constant: true
value: 0.0011
type: Parameter

910903
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

metaid_0000052
constant: true
value: 15.2
type: Parameter

metaid_0000039
constant: true
value: 0.5
type: Parameter

metaid_0000262
kinetic law: 912199
product: 912187
reactant: 912175
reactant: 912163
fast: false
reversible: false
name: R33
type: Reaction

912066
stoichiometry: 1.0
species: metaid_0000187
type: SpeciesReference

912018
stoichiometry: 1.0
species: metaid_0000132
type: SpeciesReference

metaid_0000062
constant: true
value: 0.043
type: Parameter

910006
stoichiometry: 1.0
species: metaid_0000155
type: SpeciesReference

metaid_0000049
constant: true
value: 1.0
type: Parameter

911872
stoichiometry: 1.0
species: metaid_0000185
type: SpeciesReference

metaid_0000137
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: Xa_f
type: Species

909799
stoichiometry: 1.0
species: metaid_0000124
type: SpeciesReference

metaid_0000221
kinetic law: 910552
product: 910539
product: 910527
reactant: 910515
fast: false
reversible: false
name: Factor VIII activation
type: Reaction

909361
stoichiometry: 1.0
species: metaid_0000133
type: SpeciesReference

metaid_0000011
constant: true
value: 0.057
type: Parameter

metaid_0000021
constant: true
value: 0.05
type: Parameter

908975
stoichiometry: 1.0
species: metaid_0000117
type: SpeciesReference

metaid_0000123
constant: false
boundary condition: false
has only substance units: false
initial concentration: 10.0
initial amount: NaN
in compartment: metaid_0000114
name: VII_f
type: Species

metaid_0000094
constant: true
value: 4.9E-7
type: Parameter

911363
stoichiometry: 1.0
species: metaid_0000175
type: SpeciesReference

metaid_0000038
constant: true
value: 11.5
type: Parameter

metaid_0000063
constant: true
value: 0.1
type: Parameter

metaid_0000010
constant: true
value: 0.145
type: Parameter

metaid_0000220
kinetic law: 910503
product: 910491
reactant: 910479
reactant: 910467
fast: false
reversible: false
name: Xa_VIII binding
type: Reaction

metaid_0000024
constant: true
value: 0.115
type: Parameter

metaid_0000138
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: Xa_l
type: Species

metaid_0000134
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: IXa_l
type: Species

metaid_0000095
constant: true
value: 2.3E-6
type: Parameter

metaid_0000077
constant: true
value: 15.0
type: Parameter

metaid_0000124
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: VII_l
type: Species

metaid_0000210
kinetic law: 910018
product: 910006
reactant: 909994
fast: false
reversible: false
name: Factor X activation
type: Reaction

metaid_0000260
constant: true
value: 1.4E-6
type: Parameter

910891
stoichiometry: 1.0
species: metaid_0000166
type: SpeciesReference

910222
stoichiometry: 1.0
species: metaid_0000122
type: SpeciesReference

metaid_0000050
constant: true
value: 0.05
type: Parameter

metaid_0000037
constant: true
value: 0.05
type: Parameter

910734
stoichiometry: 1.0
species: metaid_0000130
type: SpeciesReference

metaid_0000250
kinetic law: 911956
product: 911944
reactant: 911932
reactant: 911920
fast: false
reversible: false
type: Reaction

metaid_0000064
constant: true
value: 2.1
type: Parameter

908987
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

metaid_0000135
constant: false
boundary condition: false
has only substance units: false
initial concentration: 170.0
initial amount: NaN
in compartment: metaid_0000114
name: X_f
type: Species

metaid_0000139
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: APC_f
type: Species

911884
stoichiometry: 1.0
species: metaid_0000140
type: SpeciesReference

metaid_0000078
constant: true
value: 0.05
type: Parameter

metaid_0000125
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.1
initial amount: NaN
in compartment: metaid_0000114
name: VIIa_f
type: Species

910515
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

metaid_0000096
constant: true
value: 6.83E-6
type: Parameter

911011
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

metaid_0000023
constant: true
value: 0.05
type: Parameter

metaid_0000115
constant: false
boundary condition: false
has only substance units: false
initial concentration: 1400.0
initial amount: NaN
in compartment: metaid_0000114
name: II_f
type: Species

910090
stoichiometry: 1.0
species: metaid_0000151
type: SpeciesReference

911399
stoichiometry: 1.0
species: metaid_0000175
type: SpeciesReference

metaid_0000159
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: IXa_VIIIa_X_l
type: Species

metaid_0000213
kinetic law: 910162
product: 910150
product: 910138
reactant: 910126
fast: false
reversible: false
name: TF_VII activation
type: Reaction

metaid_0000098
constant: true
value: 6.94
type: Parameter

metaid_0000129
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
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notes: This model is from the article: Modelling thrombin generation in human ovarian follicular fluid Bungay Sharene D., Gentry Patricia A., Gentry Rodney D. Bulletin of Mathematical Biology Volume 68, Issue 8, 12 July 2006, Pages 2283-302 16838084 , Abstract: A mathematical model is constructed to study thrombin production in human ovarian follicular fluid. The model results show that the amount of thrombin that can be produced in ovarian follicular fluid is much lower than that in blood plasma, failing to reach the level required for fibrin formation, and thereby supporting the hypothesis that in follicular fluid thrombin functions to initiate cellular activities via intracellular signalling receptors. It is also concluded that the absence of the amplification pathway to thrombin production in follicular fluid is a major factor in restricting the amount of thrombin that can be produced. Titration of the initial concentrations of the various reactants in the model lead to predictions for the amount of tissue factor and phospholipid that is required to maintain thrombin production in the follicle, as well as to the conclusion that tissue factor pathway inhibitor has little effect on the time that thrombin generation is sustained. Numerical experiments to determine the effect of factor V, which is at a much reduced level in follicular fluid compared to plasma, and thrombomodulin, illustrate the importance for further experimental work to determine values for several parameters that have yet to be reported in the literature.
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reversible: false
name: Factor V activation
type: Reaction

911216
stoichiometry: 1.0
species: metaid_0000170
type: SpeciesReference

910819
stoichiometry: 1.0
species: metaid_0000158
type: SpeciesReference

909872
stoichiometry: 1.0
species: metaid_0000152
type: SpeciesReference

metaid_0000153
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: TF_VIIa_IXa_l
type: Species

909725
stoichiometry: 1.0
species: metaid_0000148
type: SpeciesReference

metaid_0000172
constant: false
boundary condition: false
has only substance units: false
initial concentration: 2.5
initial amount: NaN
in compartment: metaid_0000114
name: TFPI_f
type: Species

metaid_0000259
constant: true
value: 2.5E-6
type: Parameter

911994
stoichiometry: 1.0
species: metaid_0000170
type: SpeciesReference

912175
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

metaid_0000249
kinetic law: 911908
product: 911896
product: 911884
reactant: 911872
fast: false
reversible: false
type: Reaction

909241
stoichiometry: 1.0
species: metaid_0000128
type: SpeciesReference

910576
stoichiometry: 1.0
species: metaid_0000120
type: SpeciesReference

910624
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

metaid_0000229
kinetic law: 910939
product: 910927
product: 910915
product: 910903
reactant: 910891
fast: false
reversible: false
type: Reaction

911301
stoichiometry: 1.0
species: metaid_0000146
type: SpeciesReference

911192
stoichiometry: 1.0
species: metaid_0000171
type: SpeciesReference

metaid_0000239
kinetic law: 911423
product: 911411
reactant: 911399
reactant: 911387
fast: false
reversible: false
type: Reaction

911252
stoichiometry: 1.0
species: metaid_0000170
type: SpeciesReference

909578
stoichiometry: 1.0
species: metaid_0000142
type: SpeciesReference

metaid_0000152
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: TF_VIIa_IX_l
type: Species

metaid_0000165
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: Xa_Va_II_l
type: Species

metaid_0000175
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: TFPI_Xa_l
type: Species

910030
stoichiometry: 1.0
species: metaid_0000155
type: SpeciesReference

metaid_0000238
kinetic law: 911375
product: 911363
reactant: 911350
reactant: 911338
fast: false
reversible: false
type: Reaction

metaid_0000224
kinetic law: 910697
product: 910685
reactant: 910673
reactant: 910660
fast: false
reversible: false
type: Reaction

909652
stoichiometry: 1.0
species: metaid_0000145
type: SpeciesReference

912090
stoichiometry: 1.0
species: metaid_0000169
type: SpeciesReference

909566
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

910150
stoichiometry: 1.0
species: metaid_0000150
type: SpeciesReference

909506
stoichiometry: 1.0
species: metaid_0000139
type: SpeciesReference

909897
stoichiometry: 1.0
species: metaid_0000152
type: SpeciesReference

909811
stoichiometry: 1.0
species: metaid_0000149
type: SpeciesReference

metaid_0000164
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: VIII_IIa_l
type: Species

W3 CDTF: Thu May 12 13:58:49 BST 2011

metaid_0000174
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: IIa_AT_f
type: Species

911786
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

metaid_0000237
kinetic law: 911326
product: 911314
product: 911301
reactant: 911289
fast: false
reversible: false
type: Reaction

911640
stoichiometry: 1.0
species: metaid_0000118
type: SpeciesReference

metaid_0000223
kinetic law: 910648
product: 910636
product: 910624
reactant: 910612
fast: false
reversible: false
type: Reaction

909277
stoichiometry: 100.0
species: metaid_0000004
type: SpeciesReference

911289
stoichiometry: 1.0
species: metaid_0000177
type: SpeciesReference

metaid_0000163
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: V_IIa_l
type: Species

909409
stoichiometry: 1.0
species: metaid_0000135
type: SpeciesReference

910660
stoichiometry: 1.0
species: metaid_0000162
type: SpeciesReference

910042
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

910467
stoichiometry: 1.0
species: metaid_0000138
type: SpeciesReference

metaid_0000177
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: APC_PS_Va_l
type: Species

metaid_0000236
kinetic law: 911277
product: 911264
reactant: 911252
reactant: 911240
fast: false
reversible: false
type: Reaction

911314
stoichiometry: 1.0
species: metaid_0000170
type: SpeciesReference

metaid_0000226
kinetic law: 910795
product: 910783
reactant: 910770
reactant: 910758
fast: false
reversible: false
type: Reaction

910491
stoichiometry: 1.0
species: metaid_0000161
type: SpeciesReference

911798
stoichiometry: 1.0
species: metaid_0000184
type: SpeciesReference

metaid_0000162
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: IIa_f
type: Species

909554
stoichiometry: 1.0
species: metaid_0000141
type: SpeciesReference

metaid_0000176
constant: false
boundary condition: false
has only substance units: false
initial concentration: 0.0
initial amount: NaN
in compartment: metaid_0000114
name: TFPI_Xa_TF_VIIa_l
type: Species

909701
stoichiometry: 1.0
species: metaid_0000147
type: SpeciesReference

metaid_0000235
kinetic law: 911228
product: 911216
product: 911204
reactant: 911192
fast: false
reversible: false
type: Reaction

911749
stoichiometry: 1.0
species: metaid_0000130
type: SpeciesReference

911411
stoichiometry: 1.0
species: metaid_0000176
type: SpeciesReference

909265
stoichiometry: 1.0
species: metaid_0000129
type: SpeciesReference

metaid_0000225
kinetic law: 910746
product: 910734
product: 910722
reactant: 910709
fast: false
reversible: false
type: Reaction

ORG:
  orgname: EBI
n:
  given: Michael
  family: Schubert

W3 CDTF: Fri Apr 20 22:55:14 BST 2012