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886920
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592526
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kind: METRE
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886685
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type: LocalParameter

592199
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886894
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type: LocalParameter

594447
stoichiometry: 1.0
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886884
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type: LocalParameter

886699
units: metaid_0000015
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type: LocalParameter

592586
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kind: METRE
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886855
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type: LocalParameter

metaid_0000080
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reversible: true
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594567
stoichiometry: 1.0
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886644
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type: LocalParameter

metaid_0000090
kinetic law: 593320
modifier: 593308
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is version of: GO:0030163
fast: false
reversible: true
name: D28kB_d
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886900
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type: LocalParameter

886893
units: metaid_0000016
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type: LocalParameter

886845
units: metaid_0000015
value: 27.9812
type: LocalParameter

886658
units: metaid_0000012
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type: LocalParameter

metaid_0000027
constant: true
units: metaid_0000010
value: 0.00166112956810631
type: Parameter

886784
units: metaid_0000015
value: 0.1
type: LocalParameter

593092
stoichiometry: 1.0
species: metaid_0000056
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593428
stoichiometry: 1.0
species: metaid_0000073
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886933
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886854
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type: LocalParameter

metaid_0000081
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modifier: 592960
reactant: 592948
is version of: GO:0030163
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reversible: true
name: D28kB_deg
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594135
stoichiometry: 1.0
species: metaid_0000063
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886645
units: metaid_0000015
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type: LocalParameter

886717
units: metaid_0000015
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type: LocalParameter

886798
units: metaid_0000015
value: 0.1
type: LocalParameter

886683
units: metaid_0000015
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type: LocalParameter

886913
units: metaid_0000025
value: 21000.0
type: LocalParameter

593691
stoichiometry: 1.0
species: metaid_0000070
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metaid_0000091
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594459
stoichiometry: 1.0
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886922
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592574
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kind: DIMENSIONLESS
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592610
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886912
units: metaid_0000018
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886770
units: metaid_0000015
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type: LocalParameter

metaid_0000039
constant: true
value: 6.25
type: Parameter

886799
units: metaid_0000015
value: 0.66
type: LocalParameter

593955
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

metaid_0000029
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type: Parameter

886706
units: metaid_0000015
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type: LocalParameter

886780
units: metaid_0000013
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type: LocalParameter

metaid_0000092
kinetic law: 593404
product: 593392
reactant: 593380
reactant: 593368
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reversible: true
name: CGbinding
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594555
stoichiometry: 1.0
species: metaid_0000063
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886897
units: metaid_0000020
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type: LocalParameter

886686
units: metaid_0000016
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886607
units: metaid_0000012
value: 5.5
type: LocalParameter

886931
units: metaid_0000018
value: 0.0
type: LocalParameter

886883
units: metaid_0000016
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type: LocalParameter

886696
units: metaid_0000014
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type: LocalParameter

593224
stoichiometry: 1.0
species: metaid_0000061
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886695
units: metaid_0000015
value: 0.288
type: LocalParameter

886719
units: metaid_0000015
value: 0.66
type: LocalParameter

metaid_0000038
constant: false
value: 0.0
type: Parameter

metaid_0000093
kinetic law: 593452
product: 593440
reactant: 593428
reactant: 593416
is version of: GO:0005509
fast: false
reversible: true
name: CaD28k_med
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886781
units: metaid_0000014
value: 43.0
type: LocalParameter

886705
units: metaid_0000016
value: 6.98896
type: LocalParameter

metaid_0000028
constant: true
value: 1.0
type: Parameter

886657
units: metaid_0000015
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type: LocalParameter

886901
units: metaid_0000018
value: 0.0
type: LocalParameter

886792
units: metaid_0000015
value: 0.66
type: LocalParameter

metaid_0000037
constant: true
value: 0.105
type: Parameter

886924
units: metaid_0000018
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type: LocalParameter

886773
units: metaid_0000012
value: 5.5
type: LocalParameter

886689
units: metaid_0000014
value: 223.0
type: LocalParameter

886787
units: metaid_0000015
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type: LocalParameter

886608
units: metaid_0000013
value: 2.6
type: LocalParameter

886628
units: metaid_0000015
value: 0.66
type: LocalParameter

metaid_0000094
kinetic law: 593488
modifier: 593476
reactant: 593464
is version of: GO:0030163
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reversible: true
name: PABCa_deg
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592646
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kind: DIMENSIONLESS
type: SBMLUnit

metaid_0000084
kinetic law: 593104
product: 593092
reactant: 593080
reactant: 593068
is version of: GO:0005509
fast: false
reversible: true
name: PA_Ca
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886772
units: metaid_0000015
value: 0.288
type: LocalParameter

886648
units: metaid_0000014
value: 28.0
type: LocalParameter

886618
units: metaid_0000015
value: 1.0
type: LocalParameter

886669
units: metaid_0000015
value: 0.1
type: LocalParameter

metaid_0000036
constant: true
value: 0.1
type: Parameter

886923
units: metaid_0000018
value: 0.0
type: LocalParameter

886688
units: metaid_0000015
value: 5.6265
type: LocalParameter

886788
units: metaid_0000014
value: 43.0
type: LocalParameter

886609
units: metaid_0000012
value: 107.0
type: LocalParameter

886629
units: metaid_0000015
value: 1.0
type: LocalParameter

886890
units: metaid_0000015
value: 1.0
type: LocalParameter

592174
exponent: 2.0
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kind: METRE
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592792
stoichiometry: 1.0
species: metaid_0000059
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593536
stoichiometry: 1.0
species: metaid_0000058
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metaid_0000085
kinetic law: 593140
modifier: 593128
reactant: 593116
is version of: GO:0030163
fast: false
reversible: true
name: PABMg_deg
type: Reaction

886713
units: metaid_0000015
value: 0.288
type: LocalParameter

metaid_0000095
kinetic law: 593524
modifier: 593512
reactant: 593500
fast: false
reversible: true
name: IP3_d
type: Reaction

886649
units: metaid_0000015
value: 0.1
type: LocalParameter

886861
units: metaid_0000015
value: 0.288
type: LocalParameter

886703
units: metaid_0000015
value: 27.9812
type: LocalParameter

886619
units: metaid_0000015
value: 27.9812
type: LocalParameter

886880
units: metaid_0000013
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type: LocalParameter

592370
exponent: 1.0
scale: -6
multipler: 1.0
kind: METRE
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592308
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

886926
units: metaid_0000025
value: 21000.0
type: LocalParameter

metaid_0000035
constant: true
value: 13.25
type: Parameter

594531
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

886794
units: metaid_0000015
value: 0.288
type: LocalParameter

593608
stoichiometry: 1.0
species: metaid_0000067
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593296
stoichiometry: 1.0
species: metaid_0000076
type: SpeciesReference

592730
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kind: MOLE
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886785
units: metaid_0000015
value: 0.66
type: LocalParameter

886872
units: metaid_0000015
value: 0.1
type: LocalParameter

592598
exponent: 1.0
scale: 0
multipler: 1.0
kind: MOLE
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886891
units: metaid_0000015
value: 27.9812
type: LocalParameter

886616
units: metaid_0000015
value: 0.66
type: LocalParameter

886795
units: metaid_0000014
value: 15.0
type: LocalParameter

886702
units: metaid_0000015
value: 1.0
type: LocalParameter

metaid_0000096
kinetic law: 593559
modifier: 593548
reactant: 593536
is version of: GO:0030163
fast: false
reversible: true
name: D28k_high_d
type: Reaction

metaid_0000130
constant: true
value: 1.0
type: Parameter

592634
exponent: 1.0
scale: 0
multipler: 1.0
kind: SECOND
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886716
units: metaid_0000014
value: 28.0
type: LocalParameter

metaid_0000082
kinetic law: 593008
modifier: 592996
reactant: 592984
is version of: GO:0030163
fast: false
reversible: true
name: D28k_deg
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metaid_0000034
constant: false
value: 0.0
type: Parameter

886776
units: metaid_0000013
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type: LocalParameter

886873
units: metaid_0000015
value: 0.66
type: LocalParameter

593080
stoichiometry: 1.0
species: metaid_0000073
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592382
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886852
units: metaid_0000013
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type: LocalParameter

metaid_0000097
kinetic law: 593595
modifier: 593583
reactant: 593571
fast: false
reversible: true
name: reaction0
type: Reaction

592186
exponent: 1.0
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kind: DIMENSIONLESS
type: SBMLUnit

metaid_0000083
kinetic law: 593056
product: 593044
reactant: 593032
reactant: 593020
is version of: GO:0000287
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reversible: true
name: PA_MgD
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592150
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multipler: 1.0
kind: ITEM
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metaid_0000098
kinetic law: 593631
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is version of: GO:0030163
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reversible: true
name: PABMg_d
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886908
units: metaid_0000024
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type: LocalParameter

886727
units: metaid_0000012
value: 430.0
type: LocalParameter

metaid_0000088
kinetic law: 593248
modifier: 593236
reactant: 593224
is version of: GO:0030163
fast: false
reversible: true
name: D28kB_high_deg
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594291
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

593368
stoichiometry: 1.0
species: metaid_0000073
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886777
units: metaid_0000012
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type: LocalParameter

593871
stoichiometry: 1.0
species: metaid_0000067
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metaid_0000046
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boundary condition: false
has only substance units: false
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metaid_0000099
kinetic law: 593679
product: 593667
reactant: 593655
reactant: 593643
is version of: GO:0005509
fast: false
reversible: true
name: CD28k_high
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592454
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kind: SECOND
type: SBMLUnit

886865
units: metaid_0000015
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type: LocalParameter

886738
units: metaid_0000015
value: 0.1
type: LocalParameter

metaid_0000089
kinetic law: 593284
modifier: 593272
reactant: 593260
fast: false
reversible: true
name: CG_d
type: Reaction

593440
stoichiometry: 1.0
species: metaid_0000076
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886875
units: metaid_0000015
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type: LocalParameter

886679
units: metaid_0000014
value: 28.0
type: LocalParameter

metaid_0000047
initial amount: NaN
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has part: CHEBI:29108
has part: C00076
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substance units: metaid_0000007

886927
units: metaid_0000016
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type: LocalParameter

886665
units: metaid_0000013
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type: LocalParameter

592828
stoichiometry: 1.0
species: metaid_0000046
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886862
units: metaid_0000014
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type: LocalParameter

594027
stoichiometry: 1.0
species: metaid_0000064
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metaid_0000086
kinetic law: 593176
modifier: 593164
reactant: 593152
is version of: GO:0030163
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reversible: true
name: D28k_high_deg
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592162
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scale: 0
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kind: MOLE
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886876
units: metaid_0000012
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type: LocalParameter

592780
stoichiometry: 1.0
species: metaid_0000063
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886739
units: metaid_0000015
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type: LocalParameter

metaid_0000058
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886676
units: metaid_0000015
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type: LocalParameter

886666
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type: LocalParameter

metaid_0000048
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is: C00076
boundary condition: true
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592442
exponent: -2.0
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kind: METRE
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886726
units: metaid_0000019
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metaid_0000049
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boundary condition: false
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substance units: metaid_0000007
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886909
value: 0.27
type: LocalParameter

592430
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scale: 0
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kind: ITEM
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886919
units: metaid_0000018
value: 0.0
type: LocalParameter

metaid_0000087
kinetic law: 593212
modifier: 593200
reactant: 593188
fast: false
reversible: true
name: Ca_d
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594411
stoichiometry: 1.0
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592658
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592912
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metaid_0000059
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592840
stoichiometry: 1.0
species: metaid_0000063
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886929
units: metaid_0000016
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type: LocalParameter

886654
units: metaid_0000015
value: 27.9812
type: LocalParameter

BIOMD0000000162
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parameter: metaid_0000130
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594111
stoichiometry: 1.0
species: metaid_0000071
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886673
units: metaid_0000015
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type: LocalParameter

593895
stoichiometry: 1.0
species: metaid_0000046
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886904
units: metaid_0000024
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type: LocalParameter

886868
units: metaid_0000015
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type: LocalParameter

592706
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scale: 0
multipler: 1.0
kind: ITEM
type: SBMLUnit

886888
units: metaid_0000015
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type: LocalParameter

886898
units: metaid_0000021
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type: LocalParameter

592126
exponent: 3.0
scale: -6
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kind: METRE
type: SBMLUnit

886879
units: metaid_0000013
value: 140.0
type: LocalParameter

886655
units: metaid_0000016
value: 75.83049
type: LocalParameter

886869
units: metaid_0000014
value: 15.0
type: LocalParameter

592852
stoichiometry: 1.0
species: metaid_0000047
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886641
units: metaid_0000015
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type: LocalParameter

592502
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594195
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592478
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886675
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type: LocalParameter

594423
stoichiometry: 1.0
species: metaid_0000073
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593332
stoichiometry: 1.0
species: metaid_0000049
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886652
units: metaid_0000015
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type: LocalParameter

886916
units: metaid_0000016
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type: LocalParameter

886866
units: metaid_0000015
value: 0.66
type: LocalParameter

886642
units: metaid_0000015
value: 27.9812
type: LocalParameter

886661
units: metaid_0000013
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type: LocalParameter

886749
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type: LocalParameter

592804
stoichiometry: 1.0
species: metaid_0000061
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592114
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593416
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886651
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type: LocalParameter

592718
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kind: METRE
type: SBMLUnit

886672
units: metaid_0000015
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type: LocalParameter

886915
units: metaid_0000016
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type: LocalParameter

886709
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type: LocalParameter

886905
units: metaid_0000018
value: 0.0
type: LocalParameter

886662
units: metaid_0000012
value: 107.0
type: LocalParameter

886887
units: metaid_0000015
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type: LocalParameter

592514
exponent: 1.0
scale: 0
multipler: 1.0
kind: ITEM
type: SBMLUnit

592466
exponent: 1.0
scale: 0
multipler: 1.0
kind: DIMENSIONLESS
type: SBMLUnit

metaid_0000053
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constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 2510.04502
initial amount: NaN
in compartment: metaid_0000041
type: Species

metaid_0000117
is version of: GO:0051924
reversible: true
fast: false
modifier: 594327
product: 594303
modifier: 594315
modifier: 594339
type: Reaction
kinetic law: 594351
reactant: 594291
name: IP3R_fluxD

metaid_0000127
constant: true
value: 1.0
type: Parameter

594087
stoichiometry: 1.0
species: metaid_0000062
type: SpeciesReference

886808
units: metaid_0000012
value: 0.8
type: LocalParameter

metaid_0000139
constant: true
value: 1.0
type: Parameter

592321
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000107
constant: false
value: 0.0
type: Parameter

592235
exponent: -3.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

metaid_0000067
has part: CHEBI:25107
constant: false
type: Species
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial amount: NaN
in compartment: metaid_0000041
has part: P20472
initial concentration: 36404.27644
has part: C00305

593500
stoichiometry: 1.0
species: metaid_0000068
type: SpeciesReference

886742
units: metaid_0000015
value: 27.9812
type: LocalParameter

886670
units: metaid_0000015
value: 0.66
type: LocalParameter

592283
exponent: 3.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

592138
exponent: 2.0
scale: -6
multipler: 1.0
kind: METRE
type: SBMLUnit

metaid_0000118
kinetic law: 594399
modifier: 594387
product: 594375
reactant: 594363
is version of: GO:0051924
fast: false
reversible: true
name: SERCA_flux
type: Reaction

metaid_0000052
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 84566.35334
initial amount: NaN
in compartment: metaid_0000041
type: Species

886769
units: metaid_0000015
value: 0.1
type: LocalParameter

metaid_0000128
constant: true
value: 1.0
type: Parameter

886759
units: metaid_0000015
value: 0.288
type: LocalParameter

886809
units: metaid_0000013
value: 25.0
type: LocalParameter

metaid_0000066
is version of: P05937
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 4207.35392
initial amount: NaN
in compartment: metaid_0000041
type: Species

593715
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

593116
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

592550
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000108
kinetic law: 593979
modifier: 593967
reactant: 593955
is version of: GO:0030163
fast: false
reversible: true
name: D28kB_high_d
type: Reaction

886741
units: metaid_0000015
value: 1.0
type: LocalParameter

886731
units: metaid_0000012
value: 43.5
type: LocalParameter

593380
stoichiometry: 1.0
species: metaid_0000055
type: SpeciesReference

594171
stoichiometry: 1.0
species: metaid_0000068
type: SpeciesReference

metaid_0000115
kinetic law: 594231
modifier: 594219
product: 594207
reactant: 594195
is version of: GO:0051924
fast: false
reversible: true
name: ER_leak_flux
type: Reaction

886758
units: metaid_0000015
value: 0.66
type: LocalParameter

metaid_0000041
is: GO:0005829
constant: true
size: 14169.5000044198
spatial dimensions: 3.0
name: Cytosol
type: Compartment

metaid_0000129
constant: true
value: 1.0
type: Parameter

metaid_0000051
constant: false
boundary condition: true
has only substance units: false
substance units: metaid_0000007
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000044
type: Species

metaid_0000109
kinetic law: 594015
modifier: 594003
reactant: 593991
is version of: GO:0030163
fast: false
reversible: true
name: D28k_d
type: Reaction

886631
units: metaid_0000015
value: 27.9812
type: LocalParameter

metaid_0000069
type: Species
in compartment: metaid_0000040
is: CHEBI:29108
is: C00076
initial amount: NaN
substance units: metaid_0000007
has only substance units: false
boundary condition: true
initial concentration: 602000.0
constant: false

886744
units: metaid_0000016
value: 16.32481
type: LocalParameter

886859
units: metaid_0000015
value: 0.66
type: LocalParameter

metaid_0000079
kinetic law: 592900
modifier: 592888
reactant: 592876
fast: false
reversible: true
name: CG_deg
type: Reaction

886730
units: metaid_0000013
value: 140.0
type: LocalParameter

592223
exponent: 1.0
scale: 0
multipler: 0.001
kind: DIMENSIONLESS
type: SBMLUnit

592876
stoichiometry: 1.0
species: metaid_0000052
type: SpeciesReference

metaid_0000040
is: GO:0005576
constant: true
size: 1.0
spatial dimensions: 3.0
name: Extracellular
type: Compartment

metaid_0000116
kinetic law: 594279
modifier: 594267
product: 594255
reactant: 594243
is version of: GO:0051924
fast: false
reversible: true
name: SERCA_fluxD
type: Reaction

593152
stoichiometry: 1.0
species: metaid_0000059
type: SpeciesReference

593068
stoichiometry: 1.0
species: metaid_0000054
type: SpeciesReference

metaid_0000050
has part: C00305
boundary condition: false
initial concentration: 36404.27644
type: Species
has part: CHEBI:25107
substance units: metaid_0000007
has only substance units: false
constant: false
in compartment: metaid_0000041
initial amount: NaN
has part: P20472

metaid_0000068
type: Species
has only substance units: false
initial amount: NaN
boundary condition: false
initial concentration: 96.32
substance units: metaid_0000007
in compartment: metaid_0000041
is: C01245
constant: false
is: CHEBI:16595

592296
exponent: -1.0
scale: 0
multipler: 1.0
kind: MOLE
type: SBMLUnit

886858
units: metaid_0000015
value: 0.1
type: LocalParameter

593703
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

592984
stoichiometry: 1.0
species: metaid_0000070
type: SpeciesReference

592562
exponent: -1.0
scale: -6
multipler: 1.0
kind: METRE
type: SBMLUnit

metaid_0000078
kinetic law: 592864
product: 592852
reactant: 592840
reactant: 592828
is version of: GO:0005509
fast: false
reversible: true
name: PA_Dbinding
type: Reaction

886766
units: metaid_0000014
value: 43.0
type: LocalParameter

metaid_0000043
is: GO:0005886
constant: true
units: metaid_0000009
size: 16669.5000051998
spatial dimensions: 2.0
name: PM
type: Compartment

592259
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000103
kinetic law: 593835
modifier: 593823
reactant: 593811
fast: false
reversible: true
name: CGB_deg
type: Reaction

metaid_0000057
substance units: metaid_0000007
in compartment: metaid_0000041
is: C00305
is: CHEBI:18420
boundary condition: true
type: Species
initial concentration: 355180.0
has only substance units: false
initial amount: NaN
constant: false

592358
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

886756
units: metaid_0000015
value: 0.1
type: LocalParameter

592345
exponent: 2.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

metaid_0000077
kinetic law: 592816
product: 592804
reactant: 592792
reactant: 592780
is version of: GO:0005509
fast: false
reversible: true
name: CD28k_highDbinding
type: Reaction

metaid_0000063
constant: false
type: Species
initial concentration: 27.09
substance units: metaid_0000007
is: C00076
boundary condition: false
is: CHEBI:29108
has only substance units: false
initial amount: NaN
in compartment: metaid_0000041

593775
stoichiometry: 1.0
species: metaid_0000054
type: SpeciesReference

metaid_0000042
is: GO:0005783
constant: true
size: 2500.0
spatial dimensions: 3.0
name: ER
type: Compartment

886765
units: metaid_0000019
value: 2.7
type: LocalParameter

metaid_0000056
has only substance units: false
initial amount: NaN
constant: false
has part: P20472
initial concentration: 9827.53562
has part: CHEBI:29108
boundary condition: false
substance units: metaid_0000007
type: Species
has part: C00076
in compartment: metaid_0000041

886755
units: metaid_0000014
value: 28.0
type: LocalParameter

886735
units: metaid_0000014
value: 43.0
type: LocalParameter

metaid_0000076
is version of: P05937
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 2510.04502
initial amount: NaN
in compartment: metaid_0000041
type: Species

metaid_0000062
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 11753.6286
initial amount: NaN
in compartment: metaid_0000041
type: Species

594243
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

593188
stoichiometry: 1.0
species: metaid_0000073
type: SpeciesReference

metaid_0000104
kinetic law: 593883
product: 593871
reactant: 593859
reactant: 593847
is version of: GO:0000287
fast: false
reversible: true
name: PA_Mg
type: Reaction

886745
units: metaid_0000015
value: 5.6265
type: LocalParameter

594519
stoichiometry: 1.0
species: metaid_0000075
type: SpeciesReference

592271
exponent: 1.0
scale: 0
multipler: 1000.0
kind: DIMENSIONLESS
type: SBMLUnit

metaid_0000045
constant: false
boundary condition: true
has only substance units: false
substance units: metaid_0000007
initial concentration: 1.0
initial amount: NaN
in compartment: metaid_0000044
type: Species

592333
exponent: 1.0
scale: 0
multipler: 1.0E-12
kind: DIMENSIONLESS
type: SBMLUnit

metaid_0000055
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 84566.35334
initial amount: NaN
in compartment: metaid_0000041
type: Species

metaid_0000119
kinetic law: 594435
product: 594423
reactant: 594411
is version of: GO:0051924
fast: false
reversible: true
name: flux0
type: Reaction

592247
exponent: 1.0
scale: 0
multipler: 1.0
kind: MOLE
type: SBMLUnit

886748
units: metaid_0000014
value: 283.0
type: LocalParameter

886734
units: metaid_0000013
value: 35.8
type: LocalParameter

metaid_0000075
constant: false
is: C00076
is: CHEBI:29108
substance units: metaid_0000007
has only substance units: false
in compartment: metaid_0000040
initial concentration: 602000.0
boundary condition: true
initial amount: NaN
type: Species

metaid_0000105
kinetic law: 593919
modifier: 593907
reactant: 593895
is version of: GO:0030163
fast: false
reversible: true
name: PA_deg
type: Reaction

592948
stoichiometry: 1.0
species: metaid_0000053
type: SpeciesReference

593464
stoichiometry: 1.0
species: metaid_0000047
type: SpeciesReference

metaid_0000065
is version of: P05937
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 45649.95498
initial amount: NaN
in compartment: metaid_0000041
type: Species

593392
stoichiometry: 1.0
species: metaid_0000064
type: SpeciesReference

metaid_0000044
is: GO:0005789
constant: true
units: metaid_0000009
size: 50000.0
spatial dimensions: 2.0
name: ERM
type: Compartment

metaid_0000054
is version of: P20472
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 1928.19396
initial amount: NaN
in compartment: metaid_0000041
type: Species

594207
stoichiometry: 1.0
species: metaid_0000060
type: SpeciesReference

594303
stoichiometry: 1.0
species: metaid_0000048
type: SpeciesReference

594255
stoichiometry: 1.0
species: metaid_0000048
type: SpeciesReference

metaid_0000074
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 0.8
initial amount: NaN
in compartment: metaid_0000044
type: Species

593859
stoichiometry: 1.0
species: metaid_0000057
type: SpeciesReference

metaid_0000106
kinetic law: 593943
reactant: 593931
fast: false
reversible: true
name: IP3_degr
type: Reaction

metaid_0000064
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 11753.6286
initial amount: NaN
in compartment: metaid_0000041
type: Species

metaid_0000073
boundary condition: false
substance units: metaid_0000007
constant: false
type: Species
is: C00076
is: CHEBI:29108
initial concentration: 27.09
initial amount: NaN
has only substance units: false
in compartment: metaid_0000041

metaid_0000131
constant: true
value: 1.0
type: Parameter

593032
stoichiometry: 1.0
species: metaid_0000046
type: SpeciesReference

594363
stoichiometry: 1.0
species: metaid_0000073
type: SpeciesReference

592694
exponent: 1.0
scale: 0
multipler: 1.0E-57
kind: DIMENSIONLESS
type: SBMLUnit

886812
units: metaid_0000014
value: 43.0
type: LocalParameter

886752
units: metaid_0000015
value: 0.288
type: LocalParameter

metaid_0000032
constant: true
value: 1.0
type: Parameter

593847
stoichiometry: 1.0
species: metaid_0000054
type: SpeciesReference

886762
units: metaid_0000018
value: 0.0
type: LocalParameter

592755
exponent: 1.0
scale: -6
multipler: 1.0
kind: METRE
type: SBMLUnit

metaid_0000120
fast: false
reversible: true
type: Reaction
product: 594459
modifier: 594495
kinetic law: 594507
modifier: 594471
reactant: 594447
is version of: GO:0051924
modifier: 594483
name: IP3R_flux

metaid_0000072
initial concentration: 355180.0
initial amount: NaN
is: C00305
has only substance units: false
boundary condition: true
is: CHEBI:18420
constant: false
in compartment: metaid_0000041
type: Species
substance units: metaid_0000007

886712
units: metaid_0000015
value: 0.66
type: LocalParameter

W3 CDTF: Mon Jan 28 11:44:38 GMT 2008

metaid_0000132
constant: true
value: 1.0
type: Parameter

886626
units: metaid_0000015
value: 0.1
type: LocalParameter

metaid_0000110
kinetic law: 594051
modifier: 594039
reactant: 594027
fast: false
reversible: true
name: CGB_d
type: Reaction

886751
units: metaid_0000015
value: 0.66
type: LocalParameter

886813
units: metaid_0000015
value: 0.1
type: LocalParameter

886801
units: metaid_0000015
value: 1.0
type: LocalParameter

metaid_0000100
kinetic law: 593727
product: 593715
reactant: 593703
reactant: 593691
is version of: GO:0005509
fast: false
reversible: true
name: D28kBDbinding
type: Reaction

metaid_0000033
constant: true
value: 2.0
type: Parameter

metaid_0000121
kinetic law: 594543
product: 594531
reactant: 594519
is version of: GO:0051924
fast: false
reversible: true
name: flux1
type: Reaction

metaid_0000133
constant: true
value: 1.0
type: Parameter

metaid_0000071
substance units: metaid_0000007
is: C01245
type: Species
constant: false
has only substance units: false
is: CHEBI:16595
in compartment: metaid_0000041
initial concentration: 96.32
initial amount: NaN
boundary condition: false

metaid_0000061
is version of: P05937
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 4207.35392
initial amount: NaN
in compartment: metaid_0000041
type: Species

886639
units: metaid_0000015
value: 0.66
type: LocalParameter

886625
units: metaid_0000014
value: 283.0
type: LocalParameter

886723
units: metaid_0000018
value: 0.0
type: LocalParameter

592394
exponent: -3.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

593020
stoichiometry: 1.0
species: metaid_0000072
type: SpeciesReference

592743
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

592406
exponent: 1.0
scale: 0
multipler: 1.0
kind: MOLE
type: SBMLUnit

886611
units: metaid_0000013
value: 0.95
type: LocalParameter

metaid_0000030
constant: true
value: 0.012
type: Parameter

886791
units: metaid_0000015
value: 0.1
type: LocalParameter

metaid_0000101
kinetic law: 593763
modifier: 593751
reactant: 593739
is version of: GO:0030163
fast: false
reversible: true
name: PABCa_d
type: Reaction

592682
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000122
kinetic law: 594591
modifier: 594579
product: 594567
reactant: 594555
is version of: GO:0051924
fast: false
reversible: true
name: ER_leak_fluxD
type: Reaction

metaid_0000134
constant: true
value: 1.0
type: Parameter

metaid_0000070
is version of: P05937
constant: false
boundary condition: false
has only substance units: false
substance units: metaid_0000007
initial concentration: 45649.95498
initial amount: NaN
in compartment: metaid_0000041
type: Species

886710
units: metaid_0000015
value: 0.1
type: LocalParameter

593667
stoichiometry: 1.0
species: metaid_0000066
type: SpeciesReference

metaid_0000060
constant: false
initial concentration: 240800.0
in compartment: metaid_0000042
substance units: metaid_0000007
type: Species
is: C00076
has only substance units: false
is: CHEBI:29108
initial amount: NaN
boundary condition: true

886638
units: metaid_0000015
value: 0.1
type: LocalParameter

886724
units: metaid_0000016
value: 0.2
type: LocalParameter

metaid_0000031
constant: true
value: 1.188
type: Parameter

886763
units: metaid_0000016
value: 0.2
type: LocalParameter

metaid_0000102
kinetic law: 593799
modifier: 593787
reactant: 593775
is version of: GO:0030163
fast: false
reversible: true
name: PA_d
type: Reaction

metaid_0000113
kinetic law: 594159
modifier: 594147
reactant: 594135
fast: false
reversible: true
name: Ca_deg
type: Reaction

592670
exponent: 1.0
scale: 0
multipler: 1.0
kind: MOLE
type: SBMLUnit

886693
units: metaid_0000015
value: 0.66
type: LocalParameter

metaid_0000135
constant: true
value: 1.0
type: Parameter

886846
units: metaid_0000016
value: 3.20298
type: LocalParameter

metaid_0000123
constant: false
value: 0.0
type: Parameter

886804
units: metaid_0000016
value: 19.5243
type: LocalParameter

886816
units: metaid_0000015
value: 1.0
type: LocalParameter

593991
stoichiometry: 1.0
species: metaid_0000065
type: SpeciesReference

592418
exponent: 1.0
scale: 0
multipler: 1.0E12
kind: DIMENSIONLESS
type: SBMLUnit

593739
stoichiometry: 1.0
species: metaid_0000056
type: SpeciesReference

886622
units: metaid_0000015
value: 5.6265
type: LocalParameter

886680
units: metaid_0000015
value: 0.1
type: LocalParameter

metaid_0000114
kinetic law: 594183
product: 594171
fast: false
reversible: true
name: pulses
type: Reaction

metaid_0000136
constant: true
value: 1.0
type: Parameter

592211
exponent: 1.0
scale: 0
multipler: 1.0
kind: MOLE
type: SBMLUnit

886632
units: metaid_0000016
value: 0.16
type: LocalParameter

593931
stoichiometry: 1.0
species: metaid_0000068
type: SpeciesReference

886612
units: metaid_0000014
value: 15.0
type: LocalParameter

886805
units: metaid_0000015
value: 5.6265
type: LocalParameter

592490
exponent: -2.0
scale: 0
multipler: 1.0
kind: METRE
type: SBMLUnit

594063
stoichiometry: 1.0
species: metaid_0000063
type: SpeciesReference

593655
stoichiometry: 1.0
species: metaid_0000058
type: SpeciesReference

593811
stoichiometry: 1.0
species: metaid_0000062
type: SpeciesReference

592767
exponent: -1.0
scale: 0
multipler: 1.0
kind: SECOND
type: SBMLUnit

metaid_0000111
kinetic law: 594099
product: 594087
reactant: 594075
reactant: 594063
is version of: GO:0005509
fast: false
reversible: true
name: CG_Dbinding
type: Reaction

886621
units: metaid_0000016
value: 140.47567
type: LocalParameter

886635
units: metaid_0000014
value: 28.0
type: LocalParameter

metaid_0000137
constant: true
value: 1.0
type: Parameter

594375
stoichiometry: 1.0
species: metaid_0000060
type: SpeciesReference

886615
units: metaid_0000015
value: 0.1
type: LocalParameter

593571
stoichiometry: 1.0
species: metaid_0000074
type: SpeciesReference

886802
units: metaid_0000015
value: 27.9812
type: LocalParameter

593044
stoichiometry: 1.0
species: metaid_0000050
type: SpeciesReference

886720
units: metaid_0000015
value: 0.288
type: LocalParameter

886682
units: metaid_0000015
value: 0.66
type: LocalParameter

metaid_0000112
kinetic law: 594123
reactant: 594111
fast: false
reversible: true
name: IP3_degr1
type: Reaction

886849
units: metaid_0000015
value: 5.6265
type: LocalParameter

886634
units: metaid_0000015
value: 5.6265
type: LocalParameter

886692
units: metaid_0000015
value: 0.1
type: LocalParameter

metaid_0000138
constant: true
value: 1.0
type: Parameter

886815
units: metaid_0000015
value: 0.66
type: LocalParameter

594075
stoichiometry: 1.0
species: metaid_0000052
type: SpeciesReference

593260
stoichiometry: 1.0
species: metaid_0000055
type: SpeciesReference

593643
stoichiometry: 1.0
species: metaid_0000073
type: SpeciesReference

886700
units: metaid_0000015
value: 0.66
type: LocalParameter

886930
units: metaid_0000018
value: 0.0
type: LocalParameter

W3 CDTF: Fri Apr 20 23:35:25 BST 2012

ORG:
  orgname: California Institute of Technology
n:
  given: Harish
  family: Dharuri